LOCUS       DAVFER010000001        87284 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1105170250
            SAMEA2167659-rid19724873.denovo.001, whole genome shotgun sequence.
ACCESSION   DAVFER010000001 DAVFER010000000
VERSION     DAVFER010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2167659
            Sequence Read Archive: ERR388902
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 87284)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 87284)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928716.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928716.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 04:07:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,118
            CDSs (total)                      :: 2,073
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 120
            CDSs (without protein)            :: 120
            Pseudo Genes (ambiguous residues) :: 0 of 120
            Pseudo Genes (frameshifted)       :: 67 of 120
            Pseudo Genes (incomplete)         :: 47 of 120
            Pseudo Genes (internal stop)      :: 34 of 120
            Pseudo Genes (multiple problems)  :: 23 of 120
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..87284
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2167659-rid19724873.denovo.001"
                     /strain="1105170250"
                     /db_xref="taxon:1313"
     gene            497..1540
                     /locus_tag="VU534_000001"
     CDS             497..1540
                     /locus_tag="VU534_000001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00341 family protein"
                     /protein_id="HEU1512667.1"
                     /translation="MTNNKLYSLIEFRNKIYEELELSRSDLAILLCAMLIASIGLNMD
                     STPVIIGAMLISPLMTPILGVGLSLAIFDFKLLRKSFKILAIQILASLIASTLYFYLS
                     PISYASSEIVARTSPTIWDVLIAFVGGIAGIIGARKKETNNIVPGVAIATALMPPLCT
                     VGYAIASANLKFIIGSSYLFLINCSFIVIATYIGVRLMMVKKHYFKDNEEDSKMRRIL
                     LLVAVLLMIPSFISATTLVRETLKKESLKKFISEQFQGYNILKKTYSKKTHTLKLTIS
                     GNYLTEEELDMISSKRGDYGLSDVSVQVSQLSDSEQLSKEELVEYFFQYIKDKEAKEK
                     EKANKFDTESEEQ"
     gene            1707..3794
                     /gene="topA"
                     /locus_tag="VU534_000002"
     CDS             1707..3794
                     /gene="topA"
                     /locus_tag="VU534_000002"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HEU1512668.1"
                     /translation="MATATKKKKSTVKKNLVIVESPAKAKTIEKYLGRNYKVLASVGH
                     IRDLKKSSMSVDIENNYEPQYINIRGKGPLINDLKKEAKKANKVFLASDPDREGEAIS
                     WHLAHILNLDENDANRVVFNEITKDAVKNAFKEPRKIDMDLVDAQQARRILDRLVGYS
                     ISPILWKKVKKGLSAGRVQSIALKLIIDRENEINAFQPEEYWTVDAVFKKGTKQFHAS
                     FYGVDGKKMKLTSNNEVKEVLSRLTSKDFSVDQVDKKERKRNAPLPYTTSSMQMDAAN
                     KINFRTRKTMMVAQQLYEGINIGSGVQGLITYMRTDSTRISPVAQNEAASFITDRFGS
                     KYSKHGSKVKNASGAQDAHEAIRPSSVFNTPESIAKYLDKDQLKLYTLIWNRFVASQM
                     TAAVFDTMAVKLSQKGVQFAANGSQVKFDGYLAIYNDSDKNKMLPDMVVGDVVKQVNS
                     KPEQHFTQPPARYSEATLIKTLEENGVGRPSTYAPTIETIQKRYYVRLAAKRFEPTEL
                     GEIVNKLIVEYFPDIVNVTFTAEMEGKLDDVEVGKEQWRRVIDAFYKPFSKEVAKAEE
                     EMEKIQIKDEPAGFDCEVCGSPMVIKLGRFGKFYACSNFPDCRHTQAIVKEIGVECPS
                     CHQGQIIERKTKRNRLFYGCNRYPECEFTSWDKPVGRDCPKCGNFLMEKKVRGGGKQV
                     VCSKGDYEEEKIK"
     gene            4015..4374
                     /locus_tag="VU534_000003"
     CDS             4015..4374
                     /locus_tag="VU534_000003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaN family protein"
                     /protein_id="HEU1512669.1"
                     /translation="MRIIYLIIGFLSLTLAIVGVVLPLLPTTPFLLLSIACFSRSSKR
                     FEDWLYHTKLYQAYVADFRETKSIARERKKKIIVSIYVLMGISIYFAPLLPVKIGLGA
                     LTIFITYYLFKVIPDKE"
     gene            4467..5099
                     /locus_tag="VU534_000004"
     CDS             4467..5099
                     /locus_tag="VU534_000004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000638771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HEU1512670.1"
                     /translation="MIYEFCAENVTLLEKAMQAGARRIELCDNLAVGGTTPSYGVTKA
                     AVELAANYDTTIMTMIRPRGGDFVYNDLEIAIMLEDIRLTAQAGSQGVVFGALTADKK
                     LDKPNLEKLIAASKGMEIVFHMAFDELSDEDQAEAIDWLSQAGVTRILTRAGVSGDSL
                     EKRFVHYHRILEYAKGKIEILPGGGIDLENRQTFIDQVGVTQLHGTKVVF"
     gene            5143..5799
                     /locus_tag="VU534_000005"
     CDS             5143..5799
                     /locus_tag="VU534_000005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MmcQ/YjbR family DNA-binding protein"
                     /protein_id="HEU1512671.1"
                     /translation="MFEIFKSYQFNQEKAHDYGFIENSEVWTYSCQILQGDFVMTVSI
                     TADNVNFQVFDQETGDLYPHVYMESMRGSFVGNVREACLEILYQIRKACFDVQDFICH
                     QTKRIMTQVQEKYGNQLEYLWEKSPDTAVLRHEGNQKWYAVLMKISWNKLEKGREGQV
                     EAVNLKHDQVANLLSQKGIYPAFHMSKRYWISVSLDDTLSDEEVLELIEKSWNLTSKK
                     "
     gene            5818..6912
                     /locus_tag="VU534_000006"
     CDS             5818..6912
                     /locus_tag="VU534_000006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001010962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-isopropylmalate synthase"
                     /protein_id="HEU1512672.1"
                     /translation="MNFQLAKYSLLKRFLENIGFTTLEEYGAIFKYLIENVKTDRQII
                     YSPHCHDDLGMAVANSLAAVKNGAGRVEGTINGIRERAENAALEEIAVALNIRQDYYQ
                     VETSIVLNETINTSEMVSRFSGIPVPKNKAVVGGNTFSHESGIHQDGVLKNPLTYEII
                     TPELVGVKILLGKLSGRHAFVEKLRELALDFTEEDIKPLFAKFKALVDKKQEITDADI
                     RALVAGTMVENPEGFHFDDLQLQTHADNDIEALVSLANMDGEKVEFNATGQGSVEAIF
                     NAIDKFFNQSVRLVSYTIDAVTDGIDTQDRVLVTVENRDTETIFNAAGLDFDVLKASA
                     IVYINANTFVQKENAGEMGRSVSYHDMPSV"
     gene            6924..7961
                     /gene="leuB"
                     /locus_tag="VU534_000007"
                     /pseudo
     CDS             6924..7961
                     /gene="leuB"
                     /locus_tag="VU534_000007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399454.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydrogenase"
     gene            7958..8227
                     /locus_tag="VU534_000008"
     CDS             7958..8227
                     /locus_tag="VU534_000008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HEU1512673.1"
                     /translation="MKLDEKITLVLLIWNVIIFLIYGIDKSKARRRVWRIPEKILLIL
                     AFTFGGFGAWLAGIIFHHKTRKWYFKIVWFLGMVTTLVALYFIWR"
     gene            8231..8590
                     /gene="leuD"
                     /locus_tag="VU534_000009"
     CDS             8231..8590
                     /gene="leuD"
                     /locus_tag="VU534_000009"
                     /EC_number="4.2.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase small subunit"
                     /protein_id="HEU1512674.1"
                     /translation="MAGSSREYAAWALADYGFKVVIAGSFGDIHYNNELNNGMLPIVQ
                     PREVREKLAQLKPTDQVTVDLEQQKIISPVEEFTFEIDSEWKHKLLNSLDDIGITLQY
                     EELIAAYEKQRPAYWQD"
     gene            8809..8952
                     /locus_tag="VU534_000010"
     CDS             8809..8952
                     /locus_tag="VU534_000010"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1512675.1"
                     /translation="MTSDKAGLERKFAAKERKRNKPGVVLCGSMDELCALAQLNPEIE
                     AFY"
     gene            9213..9374
                     /locus_tag="VU534_000011"
     CDS             9213..9374
                     /locus_tag="VU534_000011"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1512676.1"
                     /translation="MVDKDGKLIPEQGGARSTSPAPVVIRKGLDIDKIMMHLSDTFNS
                     WDYRQVEYY"
     gene            9538..11469
                     /locus_tag="VU534_000012"
     CDS             9538..11469
                     /locus_tag="VU534_000012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="McrB family protein"
                     /protein_id="HEU1512677.1"
                     /translation="MNKRKVSLEDFYKWYSLNKEELLNKATVGEKFNDKLKEEFLQEW
                     PLDRILTMSIDEYVIGKGQQNKSLCYALEKGKYKNLFLGISGGSASKFGIYWNKKTNK
                     YKDQANNEISELDQRFSKLKSDLYEIIKEGIRFNFENPIFDMKRSTNEFIGRSAMVTK
                     LLCIYTEGDPFFGVNINSQKEFWNHFVSQTNQGGPYLQNHKIIELVSKTYPELEPSKL
                     GTMLFEYSKLFMENKEDNSTMDSSNNFRHQLTQSLLKSPNLILRGAPGTGKTYLAKEI
                     AKELTDGNEDQIGFVQFHPSYDYTDFVEGLRPVSNGDGAIEFRLQDGIFKDFCQKAKE
                     TQLIGGQDNFDEAWDSYLEYINVAEEKEYITKTSYLSVNSRQNLSVNYDSGVPGWSLP
                     SKYVYELYKDKNYNKQEYYKSGGKTVLETLRKRFGLKDYVSPTEIDTDKNFVFIIDEI
                     NRGEISKIFGELFFSIDPGYRGEKGSVSTQYANLHETDEKFYIPENVYIIGTMNDIDR
                     SVDTFDFAMRRRFRFVEVTVEGQAGMLDKELNIHAEEAKIRLRNLNAAIENIQELNSH
                     YHIGPSYFLKLKDVDFDYELLWSDYIKPLLEDYLRGSYDEVETLETLKKAFDLTNNEQ
                     KDQTVADDNEGDENDDADY"
     gene            11456..12772
                     /locus_tag="VU534_000013"
     CDS             11456..12772
                     /locus_tag="VU534_000013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001223073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="McrC family protein"
                     /protein_id="HEU1512678.1"
                     /translation="MRITDNQHKIIKEKFVEEYPKLSNPLLDRTLESLSQDERIFIFP
                     NDLTHTPDLDKDQKIFETVNQKIKTGNVIGFLGYGQERLTISSRFSDESNDHFLHYLL
                     NKVLHINLTSLDVALSREERLYQLLVYLFPKYLQAAIRKGLYKEYHRFSHNDSHVKGV
                     IDVRNHLKKNLPFTGNIAYATREFTYDNPLMQLVRHTIEYIKNQKSIGQGVLDNLSTS
                     RENVSEIVRVTPSYKLADRAKIIRGNQSKPIRHAYFHEYRNLQELCLMILNQEKHGLG
                     YQDQKIYGILFDVAWLWEEYVYTLLPKGFVHPRNKDKTDGISVFSVGKRKVYPDFYDR
                     ERKIVLDAKYKKLELTEKGINREDLFQLISYSYILKAEKAGLIFPSMEQSVNSEIGKV
                     AGYGAQLKKWSIRIPQNASFYSTFCKMMENSEENFKAIIDEEVGRK"
     gene            12947..13933
                     /locus_tag="VU534_000014"
     CDS             12947..13933
                     /locus_tag="VU534_000014"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007516839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HEU1512679.1"
                     /translation="MLNEFPIFDYEDIQLIPNKCVIKSRAEADTSVTLGNHTFKLPVV
                     PANMQTILDENVAEQLAKGGYFYIMHRFDEAGRIPFIKRMHNQGLIASISVGVKDYEY
                     DFVSQLKADTPEYITIDIAHGHADSVISMIQHIKKELPDTFVIAGNVGTPEAVRELEN
                     AGADATKVGIGPGKVCITKVKTGFGTGGWQLAALRWCAKAARKPIIADGGIRTHGDIA
                     KSIRFGASMIMIGSLFAGHIESPGKTIEVDGEQFKEYYGSASQYQKGAYKNVEGKRIL
                     LPAKGHLQDTLTEMEQDLQSAISYAGGRQVADLKHVDYVIVKNSIWNGDASH"
     gene            13997..14068
                     /locus_tag="VU534_000015"
     tRNA            13997..14068
                     /locus_tag="VU534_000015"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:14030..14032,aa:Arg,seq:ccg)
     gene            14251..14949
                     /locus_tag="VU534_000016"
     CDS             14251..14949
                     /locus_tag="VU534_000016"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HEU1512680.1"
                     /translation="MKELQTVLKNHFAIEFADKKLLETAFTHTSYANEHRLLKISHNE
                     RLEFLGDAVLQLLISEYLYKKYPKKPEGDLSKLRAMIVREESLAGFARDCQFDQFIKL
                     GKGEEKSGGRNRDTILGDAFEAFLGALLLDKDVAKVKEFIYQVMIPKVEAGEFEMITD
                     YKTHLQELLQINGDVAIRYQVISETGPAHDKVFDVEVLVEGKSIGQGQGRSKKLAEQE
                     AAKNAVEKGLDSCI"
     gene            14940..18479
                     /gene="smc"
                     /locus_tag="VU534_000017"
     CDS             14940..18479
                     /gene="smc"
                     /locus_tag="VU534_000017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000280891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HEU1512681.1"
                     /translation="MYLKEIEIQGFKSFADKTKVVFDQGVTAVVGPNGSGKSNITESL
                     RWALGESSVKSLRGGKMPDVIFAGTESRKPLNYASVVVTLDNHDGFIKDAGQEIRVER
                     HVYRSGDSEYKIDGKKVRLRDIHDLFLDTGLGRDSFSIISQGKVEEIFNSKPEERRAI
                     FEEAAGVLKYKTRRKETESKLQQTQDNLDRLEDIIYELDNQIKPLEKQAENARKFLDL
                     EGQRKAIYLDVLVAQIKENKAELESTEEELTQVQELLMSYYQKREKLEEENQTLKKQR
                     QDLQAEMAKDQGSLMDLTSLISDLERKLALSKLESEQVALNQQEAQARLAALEDKRNS
                     LSKEKSDKESSLALLEGNLVQNNQKLNRLEAELLAFSDDPDQMIELLRERFVALLQEE
                     ADVSNQLTRIENELENSRQLSQKQADQLEKLKEQLAIAKEKASQQKEELETAKEQVQK
                     LLADYQAIAKEQEEQKTSYQAQQSQLFDRLDNLKNKQARAQSLENILRNHSNFYAGVK
                     SVLQEKDRLGGIIGAVSEHLTFDVYYQTALEIALGASSQHIIVEDEESATKAIDFLKR
                     NRAGRATFLPLTTIKARTISSQNQDAIAVSPGFLGMADELVTFDTRLEAIFKNLLATT
                     AIFDTVEHARAAARQVRYQVRMVTLDGTELRTGGSYAGGANRQNNSIFIKPELEQLQK
                     EIAEEEASLGSEEATLKTLQDEMARLTESLEAIKSQGEQARIQEQGLFLAYQQTSQQV
                     EELETLWKLQEEEIDRLSEGDWQADKENCQERLAAISSDKQNLEAEIEEIKSNKNAIQ
                     ERYQNLQEELAQARLLKTELQGQKRYEVADIERLGKELDNLDFEQEEIQRLLQEKIDN
                     LEKVDTELLSQQAEESKTQKTNLQQGLIRKQFELDDIEGQLDDIASHLDQARQQNEEW
                     IRKQTRAEAKKEKVSERLRHLQSQLTDQYQISYTEALEKAHELENLNLAEQEVKDLEK
                     AIRSLGPVNLDAIEQYEEVHNRLDFLNSQRDDILSAKNLLLETITEMNDEVKERFKST
                     FEVIRESFKVTFKQMFGGGQADLILTEGDLLTAGVEISVQPPGKKIQSLNLMSGGEKA
                     LSALALLFSIIRVKTIPFVILDEVEAALDEANVKRFGDYLNRFDKDSQFIVVTHRKGT
                     MAAADSIYGVTMQESGVSKIVSVKLKDLESIEG"
     gene            18476..19270
                     /locus_tag="VU534_000018"
     CDS             18476..19270
                     /locus_tag="VU534_000018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000153012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEU1512682.1"
                     /translation="MTIKLVATDMDGTFLDGNGRFDMDRLKSLLVSYKEKGIYFAVAS
                     GRGFLSLEKLFAGVRDDIIFIAENGSLVEYQGQDLYEATMSRDFYLATFEKLKTSPYV
                     DINKLLLTGKKGSYVLDTVDETYLKVSQHYNENIQKVASLEDITDDIFKFTTNFTEET
                     LEDGEAWVNENVPGVKAMTTGFESIDIVLDYVDKGVAIVELVKKLGITMDQVMAFGDN
                     LNDLHMMQVVGHPVAPENARPEILELAKTVIGHHKERSVIAYMEGL"
     gene            19270..20088
                     /locus_tag="VU534_000019"
     CDS             19270..20088
                     /locus_tag="VU534_000019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEU1512683.1"
                     /translation="MADIKLIALDLDGTLLTTDKRLTDRTKETLQAARDRGIKVVLTT
                     GRPLKAMDFFLHELGTDGQEDEYTITFNGGLVQKNTGEILDKTVFSYDDVARLYEETE
                     KLSLPLDAISEGTVYQIQSDQESLYAKFNPALTFVPVDFEDLSSQMTYNKCVTAFAQE
                     PLDAAIQKISPELFDQYEIFKSREMLLEWSPKNVHKATGLAKLISHLGIDQSQVMACG
                     DEANDLSMIEWAGLGVAMQNAVPEVKAAANVVTPMTNDEEAVAWAIEEYVLKEN"
     gene            20092..21381
                     /gene="ftsY"
                     /locus_tag="VU534_000020"
     CDS             20092..21381
                     /gene="ftsY"
                     /locus_tag="VU534_000020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HEU1512684.1"
                     /translation="MGLFDRLFGKKEEPKIEEVVKEALENLDLSEDVDPTFTEVEEVS
                     QEEAEVEIVEQAVFQEEEIQDTVEESQDSEPAVGVSQEEIEELPNSEELPEEEKLEHE
                     GTVEENNSEVLEPEAPQTEETVQEKYDRSLKKTRTGFGARLNAFFANFRSVDEEFFEE
                     LEELLIMSDVGVQVASNLTEELRYEAKLENAKKPDVLRRVIIEKLVELYEKDGSYDES
                     IHFQDNLTVMLFVGVNGVGKTTSIGKLAHRYKQAGKKVMLVAADTFRAGAVAQLAEWG
                     RRVDVPVVTGPEKADPASVVFDGMERAVTEGIDILMIDTAGRLQNKDNLMAELEKIGR
                     IIKRVVPEAPHETFLALDASTGQNALVQAKEFSKITPLTGIVLTKIDGTARGGVVLAI
                     REELNIPVKLIGFGEKIDDIGEFNSENFMKGLLEGLI"
     gene            complement(21427..22914)
                     /locus_tag="VU534_000021"
     CDS             complement(21427..22914)
                     /locus_tag="VU534_000021"
                     /EC_number="1.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000096131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate dehydrogenase"
                     /protein_id="HEU1512685.1"
                     /translation="MSSKVIVTIFGASGDLAKRKLYPSLFRLYQSGNLSKHFAVIGTA
                     RRPWSKEYFESVVVESILDLADSTEQAQEFASHFYYQSHDVNDSEHYIALRQLQAELN
                     EKYQAEHNKLFFLSMAPQFFGTIAKHLKSENIVDGKGFERLIVEKPFGTDYATASKLN
                     DELLATFDEEQIFRIDHYLGKEMIQSIFAVRFANLIFENVWNKDFIDNVQITFAERLG
                     VEERGGYYDQSGALRDMVQNHTLQLLSLLAMDKPASFTKDEIRAEKIKVFKNLYHPTD
                     EELKEHFIRGQYRSGKIDGMKYISYRSEPNVNPESTTETFTSGAFFVDSDRFRGVPFF
                     FRTGKRLTEKGTHVNIVFKQMDSIFGEPLAPNILTIYIQPTEGFSLSLNGKQVGEEFN
                     LAPNSLDYRTDATATGASPEPYEKLIYDVLNNNSTNFSHWDEVCASWKLIDRIEKLWA
                     ENGAPLHDYKAGSMGPQASFDLLEKFGAKWTWQPDITYRQDGRLE"
     gene            complement(23063..23803)
                     /locus_tag="VU534_000022"
     CDS             complement(23063..23803)
                     /locus_tag="VU534_000022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEU1512686.1"
                     /translation="MAKLKIDVNDLHKHYGKNEVLKGITTKFYEGDVVCIIGPSGSGK
                     STFLRSLNLLEEVTSGHITVNGYDLTEKTTNVDHVRENIGMVFQHFNLFPHMSVLDNI
                     TFAPIEHKLMTKEEAEELGMELLEKVGLADKANANPDSLSGGQKQRVAIARGLAMNPD
                     IMLFDEPTSALDPEMVGDVLNVMKELAEQGMTMIIVTHEMGFARQVANRVIFTADGEF
                     LEDGTPDQIFDNPQHPRLKEFLDKVLNV"
     gene            complement(23803..25968)
                     /locus_tag="VU534_000023"
     CDS             complement(23803..25968)
                     /locus_tag="VU534_000023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HEU1512687.1"
                     /translation="MKKKFLAFLLILFPIFSLGIAKAETIKIVSDTAYAPFEFKDSDQ
                     TYKGIDVDIINKVAEIKGWNIQMSYPGFDAAVNAVQAGQADAIMAGMTKTKEREKVFT
                     MSDTYYDTKVVIATTKSHKISKYDQLTGKTVGVKNGTAAQRFLETIKDKYGFTIKTFD
                     TGDLMNNSLSAGAIDAMMDDKPVIEYAINQGQDLHIEMDGEAVGSFAFGVKKGSKYEH
                     LVTEFNQALSEMKKDGSLDKIIKKWTASSSSAVPTTTTLAGLKAIPVKAKYIIASDSS
                     FAPFVFQNSSNQYTGIDMELIKAIAKDQGFEIEITNPGFDAAISAVQAGQADGIIAGM
                     SVTDARKATFDFSESYYTANTILGVKESSNIASYEDLKGKTVGVKNGTASQTFLTENQ
                     SKYGYKIKTFADGSSMYDSLNTGAIDAVMDDEPVLKYSISQGQKLKTPISGTPIGETA
                     FAVKKGANPELIEMFNNGLANLKANGEFQKILDKYLASESSTASTSTVDETTLWGLLQ
                     NNYKQLLSGLGITLALALISFAIAIVIGIIFGMFSVSPYKSLRVISEIFVDVIRGIPL
                     MILAAFIFWGIPNFIESITGQQSPINDFVAGTIALSLNAAAYIAEIVRGGIQAVPVGQ
                     MEASRSLGISYGKTMRKIILPQATKLMLPNFVNQFVIALKDTTIVSAIGLVELFQTGK
                     IIIARNYQSFKMYAILAIFYLVIITLLTRLAKRLEKRIR"
     gene            26138..27091
                     /locus_tag="VU534_000024"
     CDS             26138..27091
                     /locus_tag="VU534_000024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000792120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU1512688.1"
                     /translation="MKNKRIFKDFQASKMSLNIYTSPLLAFVFVFIGEFVAFTLYGIG
                     LLALIGLARNFGEAGQNLASYLQTLHQSLTDKTSDFRLILGLLAFGFILNTVFRWTRK
                     VEKRPIRTLGFYRENFLSNLLKGFSLGLALFLLTLLGLVVLGQYRLESIHLNPYSLAF
                     VVFTIPFWILQGTAEEVVARAWLLPQLASRTNLKLAILISSLFFTLLHMGNSGLTPLS
                     LVNLFLFGVAMALYLLKTDTVWGVAGIHGAWNFAQGNLFGILVSGQPSGTSLMTFLPQ
                     GNQDWLSGGSFGIEGSIMTSLVLLLLIVYLANKLKKENERM"
     gene            27168..29156
                     /gene="uvrB"
                     /locus_tag="VU534_000025"
     CDS             27168..29156
                     /gene="uvrB"
                     /locus_tag="VU534_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit B"
                     /protein_id="HEU1512689.1"
                     /translation="MINHITDNQFKLVSKYQPSGDQPQAIEQLVDNIEGGEKAQILMG
                     ATGTGKTYTMSQVISKVNKPTLVIAHNKTLAGQLYGEFKEFFPENAVEYFVSYYDYYQ
                     PEAYVPSSDTYIEKDSSVNDEIDKLRHSATSALLERNDVIVVASVSCIYGLGSPKEYA
                     DSVVSLRPGLEISRDKLLNDLVDIQFERNDIDFQRGRFRVRGDVVEIFPASRDEHAFR
                     VEFFGDEIDRIREVEALTGQVLGEVDHLAIFPATHFVTNDDHMEVAIAKIQAELEEQL
                     AVFEKEGKLLEAQRLKQRTEYDIEMLREMGYTNGVENYSRHMDGRSEGEPPYTLLDFF
                     PDDFLIMIDESHMTIGQIKGMYNGDRSRKEMLVNYGFRLPSALDNRPLRREEFESHVH
                     QIVYVSATPGDYENEQTETVIEQIIRPTGLLDPEVEVRPTMGQIDDLLGEINARVEKN
                     ERTFITTLTKKMAEDLTDYFKEMGIKVKYMHSDIKTLERTEIIRDLRLGVFDVLVGIN
                     LLREGIDVPEVSLVAILDADKEGFLRNERGLIQTIGRAARNSEGHVIMYADTVTQSMQ
                     RAIDETARRRKIQMAYNEEHGIVPQTIKKEIRDLIAVTKAVAKEEDKEVDINSLNKQE
                     RKELVKKLEKQMQEAVEVLDFELAAQIRDMMLEVKALD"
     gene            29166..29729
                     /locus_tag="VU534_000026"
     CDS             29166..29729
                     /locus_tag="VU534_000026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU1512690.1"
                     /translation="MIYLRKLKKEDLMSLWEMAYSQLNPVWKQYDAPYYDDYQYFSNF
                     KEFELQKSESILSNSNRLGIFVDDKLVGTVSRYWVCKETRWMELGIGIYDKKFWNTGI
                     GKVAMLQWIDRTFQDYLELEHLGLTTWSGNIGMMKLAEKLRMKKEAHIPKVRYYQGKY
                     FDSIKYGILREDWEKINDGYYQINGNS"
     gene            29695..30183
                     /locus_tag="VU534_000027"
     CDS             29695..30183
                     /locus_tag="VU534_000027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU1512691.1"
                     /translation="MTVIIKSMETPEEIEGKSFVHWQTWREAYDDLLPAEFQETMTLE
                     RCRLFSQKYPENTLIAMDGVKIVGFISYGNCRDETIQAGEIIALYVLKDYYGKGIAQK
                     LVKAALTDLNHFSEIFLWVLKDNKRAIAFYQKMGFTFDGQEKILELGKPIKEKRMVFY
                     SK"
     gene            30252..30719
                     /locus_tag="VU534_000028"
     CDS             30252..30719
                     /locus_tag="VU534_000028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000085289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HEU1512692.1"
                     /translation="MSRSQLTILTNICLIEDLETQRVVMQYRAPENNRWSGYAFPGGH
                     VENDEAFAESVIREIYEETGLTIQNPQLVGIKNWPLDTGGRYIVICYKATEFSGTLQS
                     SEEGEVSWVQKDQIPNLNLAYDMLPLMEMMEAPDKSEFFYPRRTEDDWEKKIF"
     gene            complement(30716..31231)
                     /locus_tag="VU534_000029"
     CDS             complement(30716..31231)
                     /locus_tag="VU534_000029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HEU1512693.1"
                     /translation="MTKDRKQALLQLLKEAPKALNGQRLAEHFHVTRQVIVQDIAILR
                     ADGSPILSTNRGYIYKDANANTYHHKLFKVKHEVEEIGRELLAIVDNGGRVQNILIDH
                     PVYGEIETLLKLTCRRDVQHFLEQVERSDFKPISELTDGIHYHLVEAETQQDLHYIEE
                     ALDQLGYLVKD"
     gene            complement(31243..31770)
                     /locus_tag="VU534_000030"
     CDS             complement(31243..31770)
                     /locus_tag="VU534_000030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEU1512694.1"
                     /translation="MNTRKKTQFMTMTALLTAIAILIPIVMPFKIVIPPASYTLGSHI
                     AIFIAMFLSPLMAVFVILASSFGFLMAGYPMVIVFRAFSHISFGALGALYLQKFPDTL
                     DKPKSSWIFNFVLAVVHALAEVLACVVFYATSGTNVENMFYVLFVLVGFGTIIHSMVD
                     YTLALAVYKVLRKRR"
     gene            complement(32052..32615)
                     /locus_tag="VU534_000031"
     CDS             complement(32052..32615)
                     /locus_tag="VU534_000031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEU1512695.1"
                     /translation="MKKRSNIAPIAIFFATMLVIHFLSSLIFNLFPFPIKPTIVHIPV
                     IIASIIYGPRVGVTLGFLMGLLSLTVNTITILPTSYLFSPFVPNGNIYSAIIAIVPRI
                     LIGLTPYLVYKLMKNKTGLILAGALGSLTNTIFVLGGIFFLFGNVYNGNIQLLLATVI
                     STNSIAELVISAILTLAIVPRLQTLKK"
     gene            complement(32599..33150)
                     /gene="coaC"
                     /locus_tag="VU534_000032"
     CDS             complement(32599..33150)
                     /gene="coaC"
                     /locus_tag="VU534_000032"
                     /EC_number="4.1.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenoylcysteine decarboxylase"
                     /protein_id="HEU1512696.1"
                     /translation="MANILLAVTGSIASYKSADLVSSLKKQGHQVTVLMTQAATEFIQ
                     PLTLQVLSQNPVHLDVMKEPYPDQVNHIELGKKADLFIVVPATANTIAKLAHGFADNM
                     VTSTALALPSHIPKLIAPAMNTKMYDHPVTQNNLKTLETYGYQLIAPKESLLACGDHG
                     RGALADLTIILERIKETIDEKTL"
     gene            complement(33162..33851)
                     /gene="coaB"
                     /locus_tag="VU534_000033"
     CDS             complement(33162..33851)
                     /gene="coaB"
                     /locus_tag="VU534_000033"
                     /EC_number="6.3.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000699493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase"
                     /protein_id="HEU1512697.1"
                     /translation="MKILVTSGGTSEAIDSVRSITNHSTGHLGKIITETLLSAGYEVC
                     LITTKRALKPEPHPNLSIREITNTKDLLIEMQERVQDYQVLIHSMAVSDYTPVYMTGL
                     EEVQASSNLKEFLSKQNHQAKISSTDEVQVLFLKKTPKIISLVKEWNPTIHLIGFKLL
                     VDVTEDHLVDIARKSLIKNQADLIIANDLTQISADQHRAIFVEKNQLQTVQTKEEIAE
                     LLLEKIQAYHS"
     gene            34081..35751
                     /locus_tag="VU534_000034"
     CDS             34081..35751
                     /locus_tag="VU534_000034"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HEU1512698.1"
                     /translation="MKTDIEIAQSIELKPIVDVVEKLGISYDDLELYGKYKAKLSFDK
                     IRAVESNPVGKLILVTAINPTPAGEGKSTLTIGLADALNKIGKKTMIAIREPSLGPVM
                     GIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALIDNHLHQGNELGIDQRR
                     ILWKRVVDLNDRTLRHVTVGLGGPLNGIPREDGFDITVASEIMAILCLATDIEDLKRR
                     LANIVIGYRYDRTPVSVGDLQVEGALALILKDAIKPNLVQTIYGTPAFVHGGPFANIA
                     HGCNSVLATTTALHLADYTVTEAGFGADLGAEKFLDIKTPNLPTSPDAVVIVATLRAL
                     KMNGGVAKDALTEENVEAVRAGFANLKRHVENIRKFGIPAVVAINEFVSDTEAEIAAL
                     KELCASIDVPVELASVWADGAEGGVALAETVVKTIAENPANYKRLYDNDLSVQEKIEK
                     IVTEIYRGSKVNFEKKAQTQIAQIVQNGWDKLPICMAKTQYSFSDNPNALGAPENFEI
                     TIRELVPKLGAGFIVALTGDVMTMPGLPKRPAALNMDVESDGTVLGLF"
     gene            36079..37254
                     /gene="mutY"
                     /locus_tag="VU534_000035"
     CDS             36079..37254
                     /gene="mutY"
                     /locus_tag="VU534_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HEU1512699.1"
                     /translation="MLDLKEYGIVMWPEEKVISFREKLLAWYDENKRDLPWRRSKNPY
                     HIWVSEIMLQQTRVDTVIPYYERFLDWFPTVESLATAPEESLLKAWEGLGYYSRVRNM
                     QAAAQQIMTDFGGQFPNTYEGISSLKGIGPYTAGAISSIAFNLPEPAVDGNVMRVLAR
                     LFEVNHDIGIPSNRKIFQAMMEILINPDRPGDFNQALMDLGSDIESPVNPRPEESPVK
                     DFSAAYQNGTMDRYPIKSPKKKPVPIYLKALVVKNSQGQFLLEKNESEKLLAGFWHFP
                     FIEVDNFSQEEQFDLFHQVAEESVNFGPSPEESFQQDYDLDVDWLDVCFDTVQHVFSH
                     RKWHVQIVAGQVSDFHDFSDREVRWLSPEEFKNYPLAKPQQKIWQVYAQANLDSSQD"
     gene            37310..38014
                     /locus_tag="VU534_000036"
     CDS             37310..38014
                     /locus_tag="VU534_000036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000722069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU1512700.1"
                     /translation="MKKILIVDDEKPISDIIKFNMTKEGYEVVTAFNGREALEQFEAE
                     QPDIIILDLMLPEIDGLEVAKTIRKTSSVPILMLSAKDSEFDKVIGLELGADDYVTKP
                     FSNRELQARVKALLRRSQPMPVDGQEADSKPQPIQIGDLEIVPDAYVAKKYGEELDLT
                     HREFELLYHLASHTGQVITREHLLETVWGYDYFGDVRTVDVTVRRLREKIEDTPSRPE
                     YILTRRGVGYYMRNNA"
     gene            38007..39356
                     /gene="vicK"
                     /locus_tag="VU534_000037"
     CDS             38007..39356
                     /gene="vicK"
                     /locus_tag="VU534_000037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     VicK"
                     /protein_id="HEU1512701.1"
                     /translation="MLDLLKQTIFTRDFIFILILLGFILVVTLLLLENRRDNIQLKQV
                     NQKVKDLIAGDYSKVLDMQGGSEITNITNNLNDLSEVIRLTQENLEQESKRLNSILFY
                     MTDGVLATNRRGQIIMINDTAKKQLGLVKEDVLNRSILELLKIEENYELRDLITQSPE
                     LLLDSQDINGEYLNLRVRFALIRRESGFISGLVAVLHDTTEQEKEERERRLFVSNVSH
                     ELRTPLTSVKSYLEALDEGALCETVAPDFIKVSLDETNRMMRMVTDLLHLSRIDNATS
                     HLDVELINFTAFITFILNRFDKMKGQEKEKKYELVRDYPINSIWMEIDTDKMTQVVDN
                     ILNNAIKYSPDGGKITVRMKTTEDQMILSISDHGLGIPKQDLPRIFDRFYRVDRARSR
                     AQGGTGLGLSIAKEIIKQHKGFIWAKSEYGKGSTFTIVLPYDKDAVKEEVWEDEVED"
     gene            39358..40167
                     /locus_tag="VU534_000038"
     CDS             39358..40167
                     /locus_tag="VU534_000038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HEU1512702.1"
                     /translation="MSEIGFKYSILASGSSGNSFYLETSKKKLLVDAGLSGKKITSLL
                     AEINRKPEDLDAILITHEHSDHIHGVGVLARKYGMDLYANEKTWQAMENSKYLGKVDS
                     SQKHIFEMGKTKTFGDIDIESFGVSHDAVAPQFYRFMKDDKSFVLLTDTGYVSDRMAG
                     IVENADGYLIEANHDVEILRSGSYAWRLKQRILSDLGHLSNEDGAEAMIRTLGNRTKK
                     IYLGHLSKENNIKELAHMTMVNQLAQADLGVGVDFKVYDTSPDTATPLTEI"
     gene            40258..40500
                     /locus_tag="VU534_000039"
     CDS             40258..40500
                     /locus_tag="VU534_000039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001853822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HEU1512703.1"
                     /translation="MTTITLKVSEADKTFMKAMAKFEGVSLSELIRTKTLEALEDEYD
                     ARVADLAYQEYLEDLEKGVEPITWEEMMHDLGLKDE"
     gene            40502..40756
                     /locus_tag="VU534_000040"
     CDS             40502..40756
                     /locus_tag="VU534_000040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HEU1512704.1"
                     /translation="MYKLVPTRRFIKQLKKLDRYTQKLITNYLQTNVLEDPRRHGKAL
                     VGNRVGQWRYRIGNYRVIVQIVDDELVVATLEVGHRRDIY"
     gene            40831..42702
                     /locus_tag="VU534_000041"
     CDS             40831..42702
                     /locus_tag="VU534_000041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000150981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Eco57I restriction-modification methylase
                     domain-containing protein"
                     /protein_id="HEU1512705.1"
                     /translation="MTIDISEESLAKESADLLKILLKDRTTKKSIVWATHSYELLGKG
                     FAPSDRINPSKVTGNFANLIQPRSEKSKYEQKDRTKIRAEVFTPTWLVAKQNGYVESK
                     LGSLSLEEYVDLRWLEVTCGEAPYMVTRYDTVTGEEIPLSERVGFVDRKLQRISREVS
                     DEVTFYKLVKDAYHASYGYEYQGDSLLLARENLLATFEDYYLAKTGNQPTLEQKKEIA
                     TIISYNVFQMDGLKKSSPYSAKQKQSQQLSLFADELEVQEVEESKTHIKDWKKNRMIG
                     FERLSSEESEMKFDVVIGNPPYQETGEARDEPIYHYFIDEAYKIADKSILITPARFLF
                     KAGQTPKNWMEKMLEDKHLKVQFYELKSGKVFTGTDIKGGVAITYRDVDKDLGPIGVF
                     TIFETLNGIVKKIEKHPEFETFSDLVYPQGIYRFSNKLFSDYPNAEKLQGKGTKNKIV
                     SKSLTQLDFVFKNNEEKDHVALLGRIGSERVYRYINKKYLDLPETFENYNVFVPEANG
                     SGALGEVLSTPLIGEPLIGHTDTFLSIGNFKTKFEADACIKFIKTKFARVLLGVLKVT
                     QHNSRKTWYYVPLQDFTVNSDIDWTQSVTDIDRQLDQKYDLSPEEIAFIENHVREMD"
     gene            42867..46121
                     /locus_tag="VU534_000042"
     CDS             42867..46121
                     /locus_tag="VU534_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001143847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HEU1512706.1"
                     /translation="MPVEIKTTKEIHPKIYAYTTPTVTSNEGWIKIGYTERDVTQRIK
                     EQTHTAHIATDVLWTGDAAYTEEPDKGKTFKDHDFHHFLSFHDVERRPKTEWFYFNGT
                     PEKSKNLFDKFVQHDLSGYQPGKGQDYTLRQEQEEAVAKTLAYFQEHAGGKFLWNAKP
                     RFGKTLSTYDLARRMEAVNVLIVTNRPAIANSWYDDFETFIAGQTTYKFVSESDSLKS
                     RPILSRQEFLGILADDVRQLAFISLQDLKGSVYLGGEHDKLKWVTDLHWDLLVIDEAH
                     EGVDTFKTDQAFNKIRRNFTLHLSGTSFKALAKGDFTEEQIYNWSYADEQAAKYSWSL
                     EQEEENPYESLPQLNLFTYQMSQMIGEKLEKGAQIDGENIDYVFDLSEFFATDDKGKF
                     IHEHDVRNWLDTLSSNEKYPFSTKELRNELKHTFWLLERVASAKALKALLEEHPIYEN
                     YEIVLAAGDGRMSEEDDKVKLKSLDLVRKAIAENDKTITLSVGQLTTGVTIPEWTGVL
                     MLSNLKSPALYMQAAFRAQNPYSWSDNKGNHFRKERAYVFDFAPERTLILFDEFANNL
                     LLVTAAGRGTSATREENIRELLNFFPIIAEDRAGKMVEIDAKAVLTTPRQIKAREVLK
                     RGFMSNLLFDNISGIFQASQTVLDILNELPVEKEGKVQDSSDLLDFSDVTVDDEGNAV
                     VDHEIVVNQQMRLFGEKVYGLGESVAELVTKDEERTQKQLVNDLSKTVSSVIVEELKA
                     DYSLKTRETEQIKKQITATLENEIRKNDIERKISEAHIKQELQQQLKEANDKAQKDKI
                     QEDLEKRLEENKLIHKEKLEQTLKKEVEKMPEKFIEQVEIKRVEQLKQSAQDEIRDHL
                     RGFARTIPSFIMAYGDQTLTLDNFDAFVPEHVFYEVTGITIDQFRYLRDGGQDFAGHL
                     FDKATFDEAIQEFLRKKKELADYFKDQKEDIFDYIPPQKTNQIFTPKRVVKRMVDDLE
                     KENPGIFDDPSKTFIDLYMKSGLYIAELVKRLYNSNGLKEAFPNPEERLKHILEKQVY
                     GFAPSEIIYNISTNFIFGNLSKDISRKNFVLADTIPAAKEGSIQKLVDSYFENN"
     gene            complement(46431..47417)
                     /locus_tag="VU534_000043"
     CDS             complement(46431..47417)
                     /locus_tag="VU534_000043"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019768616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HEU1512707.1"
                     /translation="MTSTKQHKKVILVGDGAVGSSYAFALVNQGIAQELGIIEIPQLH
                     EKAVGDALDLSHALAFTSPKKIYAAQYSDCADADLVVITAGAPQKPGETRLDLVGKNL
                     AINKSIVTQVVESGFKGIFLVAANPVDVLTYSTWKFSGFPKERVIGSGTSLDSARFRQ
                     ALAEKLDVDARSVHAYIMGEHGDSEFAVWSHANIAGVNLEEFLKDTQNVQEAELIELF
                     EGVRDAAYTIINKKGATYYGIAVALARITKAILDDENAVLPLSVFQEGQYGVENVFIG
                     QPAVVGAHGIVRPVNIPLNDAETQKMQASAKELQAIIDEAWKNPEFQEASKN"
     gene            47611..50079
                     /gene="gyrA"
                     /locus_tag="VU534_000044"
     CDS             47611..50079
                     /gene="gyrA"
                     /locus_tag="VU534_000044"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001152996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HEU1512708.1"
                     /translation="MQDKNLVNVNLTKEMKASFIDYAMSVIVARALPDVRDGLKPVHR
                     RILYGMNELGVTPDKPHKKSARITGDVMGKYHPHGDSSIYEAMVRMAQWWSYRYMLVD
                     GHGNFGSMDGDSAAAQRYTEARMSKIALEMLRDINKNTVDFVDNYDANEREPLVLPAR
                     FPNLLVNGATGIAVGMATNIPPHNLGETIDAVKLVMDNPEVTTKDLMEVLPGPDFPTG
                     ALVMGKSGIHKAYETGKGSIVLRSRTEIETTKTGRERIVVTEFPYMVNKTKVHEHIVR
                     LVQEKRIEGITAVRDESNREGVRFVIEVKRDASANVILNNLFKMTQMQTNFGFNMLAI
                     QNGIPKILSLRQILDAYIEHQKEVVVRRTRFDKEKAEARAHILEGLLIALDHIDEVIR
                     IIRASETDAEAQAELMSKFKLSERQSQAILDMRLRRLTGLERDKIQSEYDDLLALIAD
                     LADILAKPERVSQIIKDELDEVKRKFSDKRRTELMIGQVLSLEDEDLIEESDVLITLS
                     NRGYIKRLDQDEFTAQKRGGRGVQGTGVKDDDFVRELVSTSTHDHLLFFTNKGRVYRL
                     KGYEIPEYGRTAKGLPVVNLLKLDEDESIQTVINVESDRSDDAYLFFTTRHGIVKRTS
                     VKEFANIRQNGLKALNLKDEDELINVLLAEGDMDIIIGTKFGYAVRFNQSAVRGMSRI
                     ATGVKGVNLREGDTVVGASLITDQDEVLIITEKGYGKRTVATEYPTKGRGGKGMQTAK
                     ITEKNGLLAGLMTVQGDEDLMIITDTGVMIRTNLANISQTGRATMGVKVMRLDQDAQI
                     VTFTTVAVAEKEEVGTENETEGEA"
     gene            50079..50822
                     /gene="srtA"
                     /locus_tag="VU534_000045"
     CDS             50079..50822
                     /gene="srtA"
                     /locus_tag="VU534_000045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sortase SrtA"
                     /protein_id="HEU1512709.1"
                     /translation="MSQKNNKKKNKRKNLLTNILAGFLILLSLALIFNTQIRNIFIVW
                     NTNKYQVSQVSKEKLEENQDTEGNFDFDSVKAISSEAVLTSQWDAQKLPVIGGIAIPE
                     LEMNLPIFKGLDNVNLFYGAGTMKREQVMGEGNYSLASHHIFGVDNANKMLFSPLDNA
                     KNGMKIYLTDKNKVYTYEIREVKRVTPDRVDEVDDRDGVNEITLVTCEDLAATERIIV
                     KGDLKETKDYSQTSNEILTAFNQPYKQFY"
     gene            51066..51863
                     /locus_tag="VU534_000046"
     CDS             51066..51863
                     /locus_tag="VU534_000046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000254803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HEU1512710.1"
                     /translation="MVSSEFISKIEFACNKKESLYSQSKFKYAIRSMFAGAFLTFSTA
                     AGAVGADLINKIAPGSGRFLFPFVFAWGLAYIVFLNAELVTSNMMFLTAGSFLKKISW
                     RKTAEILLYCTLFNLIGALIAGWGFAHSAAYANLTHDSFISGVVEMKLGRSNELVLLE
                     AILANIFVNIAILSFILVKDGGAKLWLVLSAIYMFVFLTNEHIAANFASFAIVKFSVA
                     ADSIANFGVGNMLRHWGVTFIGNFIGGGLLMGLPYAFLNKNEDTYVD"
     gene            52011..52133
                     /locus_tag="VU534_000047"
     CDS             52011..52133
                     /locus_tag="VU534_000047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-acetylhomoserine sulfhydrylase"
                     /protein_id="HEU1512711.1"
                     /translation="MTCDFKFETLQLHAGQVVAPATKSRAVPIYQTTFFVFDDT"
     gene            52155..53195
                     /locus_tag="VU534_000048"
     CDS             52155..53195
                     /locus_tag="VU534_000048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001231001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-acetylhomoserine
                     aminocarboxypropyltransferase/cysteine synthase"
                     /protein_id="HEU1512712.1"
                     /translation="MRKPGNIYTRITNPTTAALEGGVEALATASGMTAVTYTILAIAH
                     AGDHVVAASTIYGGTFNLLKEPLPRYGITTTFFDIDNLEEVEAAIKDNTKLVLIETLG
                     NPLINIPDLEKLAEIAHKHQIPLVSDNTFATPYLINVFSHGVDIAIHSVTKFIGGHGT
                     TIGGIIVDSGRFDWTASGKFPQFVDEGPSCHNLSYTRDVGAAAFIIAVRVQLLRDTGA
                     ALSPFNAFLLLQRLETSSLRVERHVQNAETIVDFLVNHPKVEKVNYPKLADSPYHALA
                     EKYLPKGVGSIFTFHVKGGEEEARKVIDNLEIFSDLANAADAKSLVVHPATTTHGQLS
                     EKDLEAAGVTPN"
     gene            53366..54640
                     /locus_tag="VU534_000049"
     CDS             53366..54640
                     /locus_tag="VU534_000049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2130 domain-containing protein"
                     /protein_id="HEU1512713.1"
                     /translation="MNEIKCPNCGEVFTVNESQYAELLSQVRTAEFDKELHDRMKQEL
                     ALTEQKAMNEQQTKLAQKDQEIAQLQSQIQNFDTEKELAKKEVEQTSHEALLAKDKEV
                     QLLENQLATLRLEHENQLQKTLSDLEKERDQVKNQLLLQEKENELSLASVKQNYEAQL
                     KAASEQVEFYKNFKAQQSTKAIGESLEQYAESEFNKVRSFAFPNAYFEKDNKVSSRGS
                     KGDFIFRECDENGVEIISIMFEMKNEADGTEKKHKNADFYKELDKDRREKNCEYAVLV
                     TMLEADNDYFNTGIVDVSHEYEKMYVVRPQFFIQLIGLLRNAALNSLKYKQELALVRE
                     QNIDITHFEEDLDAFKLAFAKNYNSASTNFGKAIDEIDKAIKRMEEVKKFLTTSENQL
                     RLANNKLEDVSVKKLTRKNPTMKAKFEALKGE"
     gene            54650..55528
                     /gene="truB"
                     /locus_tag="VU534_000050"
     CDS             54650..55528
                     /gene="truB"
                     /locus_tag="VU534_000050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001013269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HEU1512714.1"
                     /translation="MNGIINLKKEAGMTSHDAVFKLRKILGTKKIGHGGTLDPDVVGV
                     LPIAVGKATRMVEFMQDEGKIYEGEITLGYSTKTEDASGEVVAETPVLSLLDEKLVDE
                     AIASLTGPITQIPPMYSAVKVNGRKLYEYARAGQEVERPERQVTIYQFERTSPISYDG
                     QLARFTFRVKCSKGTYIRTLSVDLGEKLGYAAHMSHLTRTSAAGLQLEDALALEEIAE
                     KVEAGQLDFLHPLEIGTGDLVKVFLSPEEATEVRFGRFIELDQTDKELAAFEDDKLLA
                     ILEKRGNLYKPRKVFS"
     gene            55769..56071
                     /locus_tag="VU534_000051"
     CDS             55769..56071
                     /locus_tag="VU534_000051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000985087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HEU1512715.1"
                     /translation="MMRNEFRERVEQLLQQKEINENSELSHLFRLAIQNLDRNEKYQS
                     VMANLSQGLSLYLMTHHYQAPKSVIDFGLWIAKAPSQERGRLAFLQMLAQTLQGFR"
     gene            56179..56817
                     /gene="udk"
                     /locus_tag="VU534_000052"
     CDS             56179..56817
                     /gene="udk"
                     /locus_tag="VU534_000052"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HEU1512716.1"
                     /translation="MQNRPIIIGVTGGSGGGKTSVSRAILSHFPDEKISMIEHDSYYK
                     DQSHLTFEERVKTNYDHPFAFDTDLMIEQIKELLAGRPVDIPTYDYTEHTRSSKTYRQ
                     EPQDVFIVEGILVLEDKRLRDLMDIKIFVDTDDDVRIIRRIKRDMEERGRSLDSVINQ
                     YLGVVKPMYHQFIESTKRYADIVIPEGVSNTVAIDLLTTKIAKILEEARNSK"
     gene            56945..58285
                     /locus_tag="VU534_000053"
     CDS             56945..58285
                     /locus_tag="VU534_000053"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000417449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HEU1512717.1"
                     /translation="MEKYLSVTTLTKYLKMKFDKDPYLERVYLTGQVSNFRKRPTHQY
                     FSLKDDHAVIQATIWSGIYQKLGFDLEEGMKINVIGRVQVYEPSGSYSIIIEKAEPDG
                     VGALAIQFEQLKKKLTEEGLFQERFKQALPQFSKRIGVVTSRSGAVIRDIITTVSRRF
                     PGVDILLYPTKVQGEGAAEEIARNIARANQRDDLDLLIIGRGGGSIEDLWAFNEEIVV
                     RAIFESRLPVISSVGHETDVTLADFVADRRAATPTAAAELATPVTKLDVLAHLQNQEK
                     RMVTAVRNVLSKKQEALKKCSQSVIFRQPERLYDGYLQRLDQLQLRLKQSLRTRISDN
                     KQLVQARTHQLVQLSPVTKIQRYQDRLGQLDKLLGSQMALVYDAKVAEAKRLSEALLM
                     LDTSRIVARGYAIVKKEESVVDSVESLKKKDQVTLLMRDGQVELEVKDVKTKEI"
     gene            58263..58475
                     /locus_tag="VU534_000054"
     CDS             58263..58475
                     /locus_tag="VU534_000054"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HEU1512718.1"
                     /translation="MSKQKKFEENLAELETIVQSLENGEIALEDAITAFQKGMVLSKE
                     LQATLDKAEKTLVKVMQEDGTESDFE"
     gene            58472..59347
                     /locus_tag="VU534_000055"
     CDS             58472..59347
                     /locus_tag="VU534_000055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HEU1512719.1"
                     /translation="MKKQEKLALVESALEDFYGDQQFASSLRESVLYSIHAGGKRIRP
                     FLLLEVLEALQVTIKPAHAQVATALEMIHTGSLIHDDLPAMDDDDYRRGRLTNHKKFG
                     EAMAILAGDALFLDSYALIAQADLPSQIKVDLIANLSLASGSLGMVAGQVLDMEGEHQ
                     HLSLEELQTIHANKTGKLLAYPFQAAAIIAELSPEMQVKLKTVGELIGLAFQVRDDVL
                     DVTASFEEIGKTPQKDLQAEKSTYPALLGLEESIAFCNQTLDQANEKLEEIAQQLPFE
                     TESIVSVVESLRING"
     gene            59340..60155
                     /locus_tag="VU534_000056"
     CDS             59340..60155
                     /locus_tag="VU534_000056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HEU1512720.1"
                     /translation="MAKERVDVLAYKQGLFETREQAKRGVMAGLVVAVLNGERFDKPG
                     EKIPDDTELKLKGEKLKYVSRGGLKLEKALQVFDLSVDGATTIDIGASTGGFTDVMLQ
                     NSAKLVFAVDVGTNQLAWKLRQDPRVVSMEQFNFRYAEKTDFEQEPSFASIDVSFISL
                     SLILPALHRVLADQGQVVALVKPQFEAGREQIGKNGIIRDAKVHQNVLESVTAMAVEV
                     GFSVLGLDFSPIQGGHGNIEFLAYLKKEKSASNQILAEIKEAVERAHSQFKNE"
     gene            60148..60579
                     /locus_tag="VU534_000057"
     CDS             60148..60579
                     /locus_tag="VU534_000057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001034407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEU1512721.1"
                     /translation="MNKKERLEKIRRLVTDYQIGTQEEIVEHLKEAGITATQATVSRD
                     IKELGIVKIPLRDNTYVYELPKSIVKSLQLAEDNIESAELMDKMINLQVIPGNTAFVK
                     AQLIETFADKIFSCLTDDSSILVIARSGSLAEEIFEQVKNW"
     gene            60586..62253
                     /gene="recN"
                     /locus_tag="VU534_000058"
     CDS             60586..62253
                     /gene="recN"
                     /locus_tag="VU534_000058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HEU1512722.1"
                     /translation="MLLEISIKNFAIIEAISLNFEKGMTVLTGETGAGKSIIIDAMNM
                     MLGARATTDVIRHGAPKAEIEGLFSVENSRLLQEIFDEQGLELGDEIIIRREILQNGR
                     SISRVNGQMVNLSVLRAIGQHLVDIHGQHDHEELMRPQLHIQMLDEFGDAAFWDLKET
                     YQTSFDAYRKMRKQVLEVKKNQQEHKARIEMLEFQMAEIEAANLQAGEDLALNQERDK
                     LLNHKNIADTLTNAYSMLDNEDFSSLANVRSAMNDMESVEEYDPEYREISSYLSETYY
                     VLEDISKRLEAIIEDLDFDGNRLMQVENRLDLLHTITRKYGGTVDDVLLYFAKITEEY
                     NLLTGNNLSSEDMEAELKKLEVNLVNLAGQLASARHNLAQQLEAEIKQELQDLYMEKA
                     QFQVRFSKGKFSREGNKMVEFYISTNPGEDFKPLVKVASGGELSRLMLAIKSAFSRKE
                     GKTSIVFDEVDTGVSGRVAQAIAQKIHKIGQHGQVLAISHLPQVIAIADYQFFIEKIS
                     NDHSTVSTVRLLTVEERVEEVAKMLAGDDVTEAALTQARELLRNREK"
     gene            62255..62983
                     /locus_tag="VU534_000059"
     CDS             62255..62983
                     /locus_tag="VU534_000059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000133310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine protein phosphatase"
                     /protein_id="HEU1512723.1"
                     /translation="MTDYYVIGDVHGKAGMLEDLLKTWDGQPQLLFLGDLIDRGEDSH
                     RVLEMVKDLVDNQGAICLSGNHEYMFLTWLDDPEESYDHYSRNGGDTTINSILGRPLD
                     APVDGVEDAKRVAAEAADLVEFIRQMPFVVETDKYIFVHAGIDLTLDDWHETTDYKKV
                     WLRKPFHGAENHTGKTIVFGHTPVYGLLQQERGTSELWTTEDGKIGMDGGAVYGGVLH
                     GIVFTDQGMTEHHFIENDGFVAED"
     gene            63062..64885
                     /gene="lepA"
                     /locus_tag="VU534_000060"
     CDS             63062..64885
                     /gene="lepA"
                     /locus_tag="VU534_000060"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001047203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor 4"
                     /protein_id="HEU1512724.1"
                     /translation="MNLEELKKRQEKIRNFSIIAHIDHGKSTLADRILEKTETVSSRE
                     MQAQLLDSMELERERGITIKLNAIELNYTAKDGETYIFHLIDTPGHVDFTYEVSRSLA
                     ACEGAILVVDAAQGIEAQTLANVYLALDNDLEIMPIINKIDLPAADPERVRTEIEDVI
                     GLDASEAVLASAKAGIGIEEILEQIVEKVPAPTGDVTAPLKALIFDSVYDAYRGVILQ
                     VRVMDGVVKPGDKIQLMSNSKTFDVAEVGIFTPKAVGRDFLATGDVGYIAASIKTVQD
                     TRVGDTVTLATNPAAEPLHGYKQMNPMVFAGLYPIESNKYNDLREALEKLQLNDASLQ
                     FEPETSQALGFGFRCGFLGLLHMDVIQERLEREFNIDLIMTAPSVIYKVNLTDGESMD
                     VSNPSEFPDPTKIATIEEPYVKAQIMVPQEFVGAVMELAQRKRGDFVTMDYIDDNRVN
                     VIYQIPLAEIVFDFFDKLKSSTRGYASFDYELSEYRPSKLVKMDILLNGDKVDALSFI
                     VHKDFAYERGKLIVDKLKKIIPRQQFEVPIQAAIGHKIVARTDIKALRKNVLAKCYGG
                     DVSRKRKLLEKQKAGKKRMKSIGSVEVPQEAFLSVLSMDEE"
     gene            complement(65089..65169)
                     /locus_tag="VU534_000061"
                     /pseudo
     CDS             complement(65089..65169)
                     /locus_tag="VU534_000061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            65343..65818
                     /locus_tag="VU534_000062"
                     /pseudo
     CDS             65343..65818
                     /locus_tag="VU534_000062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242196.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
     gene            65856..66158
                     /locus_tag="VU534_000063"
     CDS             65856..66158
                     /locus_tag="VU534_000063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000590570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEU1512725.1"
                     /translation="MIKILAACGAGVNSSHQIKSALEEELSNRGYDVHCDAVMVKDVN
                     EDLMKGYDIFTPIAATDLGFEPGIPVIEAGPILFRIPAMSVPVFDNIRLPAKQNMV"
     gene            66166..66971
                     /locus_tag="VU534_000064"
                     /pseudo
     CDS             66166..66971
                     /locus_tag="VU534_000064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
     gene            67020..67484
                     /locus_tag="VU534_000065"
     CDS             67020..67484
                     /locus_tag="VU534_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001146193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose epimerase"
                     /protein_id="HEU1512726.1"
                     /translation="MGGHPGFNCPLLDDEVYEDYYLEFEKEEICSVPRPFPETGMLDF
                     QDRSPWLEGQKEIDLSYDLFSTDAVTLDELQSRTIALRSLKHDKGLKVHFAEFPNLII
                     WSTLNKGPFITFEPWSGLSTSLEEGDHLEDKKNVCLLEANQVEELGFEIEVL"
     gene            67641..68066
                     /gene="lacA"
                     /locus_tag="VU534_000066"
     CDS             67641..68066
                     /gene="lacA"
                     /locus_tag="VU534_000066"
                     /EC_number="5.3.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacA"
                     /protein_id="HEU1512727.1"
                     /translation="MSIVIGADAAGLRLKEVVKDFLEKENFHLVDVTAEGQDFVDVTL
                     AVAAEVNKEEQNLGIVIDAYGAGPFIVATKIKGMVAAEVSDERSAYMTRGHNNSRMIT
                     MGAQLVGDELAKNIAKGFVNGKYDGGRHQIRVDMLNKMG"
     gene            68097..68612
                     /gene="lacB"
                     /locus_tag="VU534_000067"
     CDS             68097..68612
                     /gene="lacB"
                     /locus_tag="VU534_000067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacB"
                     /protein_id="HEU1512728.1"
                     /translation="MRIAIGCDHIVTDEKMAVSEFLKSKGYEVIDFGTYDHTRTHYPI
                     FGKKVGEAVTSGQADLGVCICGTGVGINNAVNKVPGVRSALVRDMTTALYAKEQLNAN
                     VIGFGGKITGELLMCDIIEAFIHAEYKPTEENKKLIAKIEHVESHNAQQTDANFFTEF
                     LEKWDRGEYHD"
     gene            68623..69552
                     /locus_tag="VU534_000068"
     CDS             68623..69552
                     /locus_tag="VU534_000068"
                     /EC_number="2.7.1.144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000604270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-6-phosphate kinase"
                     /protein_id="HEU1512729.1"
                     /translation="MILTVTMNPSIDISYPLDELKIDTVNRVVDVTKTAGGKGLNVTR
                     VLSEFGDSVLATGLVGGKLGEFLVEHIDNQVKKDFFSIKGETRNCIAILHGDNQTEVL
                     EKGPEVLEQEGQEFLEHFKKLLESVEVVAISGSLPAGLPVDYYASLVELANQAGKHVV
                     LDCSGAALQAVLESPHKPTVIKPNNEELSQLLGREVSEDLDELKEVLQEPLFAGIEWI
                     IVSLGANGTFAKHGDTFYKVDIPRIQVVNPVGSGDSTVAGISSGLLHKESDAELLIKA
                     NVLGMLNAQEKMTGHVNMANYQALYDQLIVKEV"
     gene            69554..70534
                     /gene="lacD"
                     /locus_tag="VU534_000069"
     CDS             69554..70534
                     /gene="lacD"
                     /locus_tag="VU534_000069"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001229146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HEU1512730.1"
                     /translation="MALTEQKRVRLEKLSDENGIISALAFDQRGALKRLMVKHQTEEP
                     TVAQMEELKVLVADELTKYASSMLLDPEYGLPATKALDEKAGLLLAYEKTGYDTTSTK
                     RLPDCLDVWSAKRIKEEGADAVKFLLYYDVDSSDELNQEKQAYIERIGSECVAEDIPF
                     FLEILAYDEKIADAGSVEYAKVKPHKVIGAMKVFSDPRFNIDVLKVEVPVNIKYVEGF
                     AEGEVVYTREEAAAFFKAQDEATNLPYIYLSAGVSAKLFQDTLVFAHESGANFNGVLC
                     GRATWAGSVEAYIKDGEAAAREWLRTTGFENIDELNKVLQRTATSWKERV"
     gene            70837..71409
                     /locus_tag="VU534_000070"
     CDS             70837..71409
                     /locus_tag="VU534_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1512731.1"
                     /translation="MVSIFLSALPMVSGSVFADSALTTVDKANDIVLNVDGNKFYNVS
                     VSEDIVNAGQILEDYFYVDKFGNINLKGTPEELAKNIGISVQEASLMYGAVKELPNVY
                     ERGPVGFRFNLGPQVRGMGGWAAGAFATGYAGWHLKQFAVNPVTSGFVAVISGAIGWA
                     VKTAVENYWTVAVATVEVPFVNLVYTIDLP"
     gene            71807..72643
                     /locus_tag="VU534_000071"
     CDS             71807..72643
                     /locus_tag="VU534_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HEU1512732.1"
                     /translation="MYRILNPMNHNVSLVRNDKGEEVIVIGKGIAFGKKKGDLIAENQ
                     VEKIFRMKTEESRENFMALLKDVPLDFITVTYEIIDKLSKKYHYPIQEYLYVTLTDHI
                     YCSYQALTQGRYKDSNLPDISAKYPVAFQIANEAFEIYRQKLADHFPEDEIIRIAYHF
                     INAEGENEVELVESIDKRKEILRNVEEVLTDYAIQRTKKNNHFYDRFMIHLNYFLDYL
                     DRSRDDNQSLLDMEDHIKQSYPKAFEIGSKIYDVITQHTGLDLYKSERVYLVLHIQRL
                     LS"
     gene            72679..72996
                     /locus_tag="VU534_000072"
     CDS             72679..72996
                     /locus_tag="VU534_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEU1512733.1"
                     /translation="MNREEVTLLGFEILAYAGDARSKLLEALKAAEAGDFEKADALVE
                     EAGSCIAEAHHAQTSLLTKEASGEDLAYSVTMMHGQDHLMTTILLKDLMHHLIELYKR
                     GVQ"
     gene            72996..74660
                     /locus_tag="VU534_000073"
     CDS             72996..74660
                     /locus_tag="VU534_000073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001037357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEU1512734.1"
                     /translation="MNKLIAFIEKGKPFFEKLSRNIYLRAIRDGFIAGMPVILFSSIF
                     ILIAFVPNSWGFKWSDEVVAFLMKPYSYSMGILALLVAGTTAKSLTDSVNRSMEKTNQ
                     INYMSTLLAADPIESGLATGFLGTKGLLSAFLAAFVTVAIYKVCVKNNVTIRMPDEVP
                     PNISQVFKDVIPFTLSVVSLYALDLLARYFVGSSVAESIGKFFAPLFSAADGYLGITI
                     IFGAFAFFWFVGIHGPSIVEPAIAAITYANAEVNLNLLQQGMHADKILTSGTQMFIVT
                     MGGTGATLVVPFMFMWLTKSKRNRAIGRASVVPTFFGVNEPILFGAPLVLNPIFFIPF
                     IFAPIANVWIFKFFIETLGMNSFTANLPWTTPAPLGLVLGTNFQVLSFILAALLIVVD
                     VVIYYPFLKVYDEQILEEERSGKSNDELKEKVAANFNTAKADAILEKAGVDAAQNTIT
                     EETNVLVLCAGGGTSGLLANALNKAAAEYNVPVKAAAGGYGAHREMLPEFDLVILAPQ
                     VASNFEDMKAETDKLGIKLAKTEGAQYIKLTRDGKGALAFVQAQFD"
     gene            74869..76275
                     /gene="lacG"
                     /locus_tag="VU534_000074"
     CDS             74869..76275
                     /gene="lacG"
                     /locus_tag="VU534_000074"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HEU1512735.1"
                     /translation="MTKTLPKDFIFGGATAAYQAEGATHTDGKGPVAWDKYLEDNYWY
                     TAEPASDFYNRYPVDLKLAEEYGVNGIRISIAWSRIFPTGYGQVNAKGVEFYHNLFAE
                     CHKRHVEPFVTLHHFDTPEALHSNGDFLNRENIEHFVDYAAFCFEEFPEVNYWTTFNE
                     IGPIGDGQYLVGKFPPGIQYDLAKVFQSHHNMMVSHARAVKLYKEKGYKGEIGVVHAL
                     PTKYPLDPENPADVRAAELEDIIHNKFILDATYLGRYSAETMEGVNHILLVNGGSLDL
                     REEDFTALEAAKDLNDFLGINYYMSDWMEAFDGETEIIHNGKGEKGSSKYQIKGVGRR
                     VAPDYVPRTDWDWIIYPQGLYDQIMRVKKDYPNYKKIYITENGLGYKDEFVDNTVYDD
                     GRIDYVKQHLEVLSDAIADGANVKGYFIWSLMDVFSWSNGYEKRYGLFYVDFETQERY
                     PKKSAHWYKKVAETQIID"
     gene            76365..76577
                     /locus_tag="VU534_000075"
     CDS             76365..76577
                     /locus_tag="VU534_000075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3884 family protein"
                     /protein_id="HEU1512736.1"
                     /translation="MNFEKCSQIPCLTSEELKSLGKWYVSTGKEWICHSDDELEEFKN
                     LFLNFINPEEWDTISFDSDFMPFQQS"
     gene            complement(76856..77617)
                     /locus_tag="VU534_000076"
     CDS             complement(76856..77617)
                     /locus_tag="VU534_000076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000917571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEU1512737.1"
                     /translation="MLKQEKLTKILEIVNSKGTITVKQIMDEIAVSDMTARRYLQELA
                     DKDLLIRVHGGAEKLRTNSLLTNERSNIEKQALQTAEKQEIAHFAGSLVEERETIFIG
                     PGTTLEFFARELPIDNIRVVTNSLPVFLILSERKLTDLILIGGNYRDITGAFVGTLTL
                     QNLSNLQFSKAFVSCNGIQNGALATFSEEEGEAQRIALNNSNKKYLLADHSKFNKFDF
                     YTFYNVSNLDTIVSDSKLSDSILFKLSKHIKVIKP"
     gene            complement(77905..78867)
                     /gene="nrdF"
                     /locus_tag="VU534_000077"
     CDS             complement(77905..78867)
                     /gene="nrdF"
                     /locus_tag="VU534_000077"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HEU1512738.1"
                     /translation="METYYKAINWNAIEDVIDKSTWEKLTEQFWLDTRIPLSNDLDDW
                     RKLSNKEKDLVGKVFGGLTLLDTMQSETGVQALRADIRTPHEEAVFNNIQFMESVHAK
                     SYSSIFSTLNTKAEIEEIFEWTNTNPYLQKKAEIVNEIYLNGSPLEKKVASVFLETFL
                     FYSGFFTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELPEEEQEKLK
                     EWMYDLLYTLYENEEGYTESLYDGVGWTEEVKTFLRYNANKALMNMGQDPLFPDSAED
                     VNPIVMNGISTGTSNHDFFSQVGNGYLLGEVEAMQDDDYNYGLH"
     gene            complement(79055..81214)
                     /gene="nrdE"
                     /locus_tag="VU534_000078"
     CDS             complement(79055..81214)
                     /gene="nrdE"
                     /locus_tag="VU534_000078"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000523276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HEU1512739.1"
                     /translation="MGLKHLEDVTYFRLNNEINRPVNGQIMLHKDKEALDAFFKENVV
                     PNTMVFDSIKDKINYLIEHNYIETAFIKKYRPEFLEELAQFIKDQNFQFKSFMAAYKF
                     YNQYALKTNDGEYYLENMEDRVFFNALYFADGNEAVAIDIANEIIHQRYQPATPSFLN
                     AGRARRGELVSCFLIQVTDDMNSIGRSINSALQLSRIGGGVGITLSNLREAGAPIKGY
                     EGAASGVVPVMKLFEDSFSYSNQLGQRQGAGVVYLNVFHPDIIAFLSTKKENADEKVR
                     VKTLSLGVVVPDKFYELARKNEEMYLFSPYSVEKEYGVPFNYIDITEKYDELVANPNI
                     RKTKIKARDLETEISKLQQESGYPYVVNIDTANRANPVDGKIIMSNLCSEILQVQEPS
                     LINDAQEFLQMGTDVSCNLGSTNVVNMMTSPDFGRSIRAMVRALTFVTDSSHIVAVPT
                     IDHGNSQAHTFGLGAMGLHSYLAQQLIEYGSPESVEFTSIYFMLMNYWTLVESNNIAR
                     ERGITFHNFEKSDYANGSYFDKYVTGEFVPTSDRVKELFKNVFIPGVADWAELRDKVQ
                     EDGLYHQNRLAVAPNGSISYINDVSASIHPITQRIEERQEKKIGKIYYPAAGLSTETI
                     PYYTSAYDMDMRKVIDVYAAATEHVDQGLSLTLFMRSDIPKGLYEWKRENKQTTRDLS
                     ILRNYAFNKGIKSIYYVRTFTDDGGEVGANQCESCVI"
     gene            complement(81295..81513)
                     /gene="nrdH"
                     /locus_tag="VU534_000079"
     CDS             complement(81295..81513)
                     /gene="nrdH"
                     /locus_tag="VU534_000079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000259243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-like protein NrdH"
                     /protein_id="HEU1512740.1"
                     /translation="MVTVYSKNNCVQCKMTKRFLDSNNVSYREINLDEQPEYVDQVKE
                     LGFSAAPVIQTPTEVFSGFQPGKLKQLA"
     gene            81864..82127
                     /locus_tag="VU534_000080"
     CDS             81864..82127
                     /locus_tag="VU534_000080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019775469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="HEU1512741.1"
                     /translation="MASKDFHVVAETGIHARPATLLVQTASKFASDITLEYKGKSVNL
                     KSIMGVMSLGVGQGADVTISAEGADADDAIAAISETMEKEGLA"
     gene            82133..83866
                     /gene="ptsP"
                     /locus_tag="VU534_000081"
     CDS             82133..83866
                     /gene="ptsP"
                     /locus_tag="VU534_000081"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HEU1512742.1"
                     /translation="MTEMLKGIAASDGVAVAKAYLLVQPDLSFETITVEDTNAEEARL
                     DAALQASQDELSVIREKAVGTLGEEAAQVFDAHLMVLADPEMISQIKETIRAKKVNAE
                     AGLKEVTDMFITIFEGMEDNPYMQERAADIRDVTKRVLANLLGKKLPNPASINEEVIV
                     IAHDLTPSDTAQLDKNFVKAFVTNIGGRTSHSAIMARTLEIAAVLGTNNITEIVKDGD
                     ILAVNGITGEVIINPTDEQAAEFKAAGEAYAKQKAEWALLKDAQTVTADGKHFELAAN
                     IGTPKDVEGVNNNGAEAVGLYRTEFLYMDSQDFPTEDEQYEAYKAVLEGMNGKPVVVR
                     TMDIGGDKELPYFDMPHEMNPFLGFRALRISISETGDAMFRTQIRALLRASVHGQLRI
                     MFPMVALLKEFRAAKAVFDEEKANLLAEGVAVADNIQVGIMIEIPAAAMLADQFAKEV
                     DFFSIGTNDLIQYTMAADRMNEQVSYLYQPYNPSILRLINNVIKAAHAEGKWAGMCGE
                     MAGDQQAVPLLVGMGLDEFSMSATSVLRTRSLMKKLDTAKMEEYANRALTECSTMEEV
                     LELQKEYVNFD"
     gene            84120..86570
                     /gene="phtA"
                     /locus_tag="VU534_000082"
     CDS             84120..86570
                     /gene="phtA"
                     /locus_tag="VU534_000082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtA"
                     /protein_id="HEU1512743.1"
                     /translation="MKINKKYLVGSAAALILSVCSYELGLYQARTVKENNRVSYIDGK
                     QATQKTENLTPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIISEE
                     LLMKDPNYKLKDEDIVNEVKGGYVIKVDGKYYVYLKDAAHADNVRTKEEINRQKQEHS
                     QHREGGTPRNDGAVALARSQGRYTTDDGYIFNASDIIEDTGDAYIVPHGDHYHYIPKN
                     ELSASELAAAEAFLSGRGNLSNSRTYRRQNSDNTSRTNWVPSVSNPGTTNTNTSNNSN
                     TNSQASQSNDIDSLLKQLYKLPLSQRHVESDGLVFDPAQITSRTARGVAVPHGDHYHF
                     IPYSQMSELEERIARIIPLRYRSNHWVPDSRPEQPSPQPTPEPSPGPQPAPNLKIDSN
                     SSLVSQLVRKVGEGYVFEEKGISRYVFAKDLPSETVKNLESKLSKQESVSHTLTAKKE
                     NVAPRDQEFYDKAYNLLTEAHKALFENKGRNSDFQALDKLLERLNDESTNKEKLVDDL
                     LAFLAPITHPERLGKPNSQIEYTEDEVRIAQLADKYTTSDGYIFDEHDIISDEGDAYV
                     TPHMGHSHWIGKDSLSDKEKVAAQAYTKEKGILPPSPDADVKANPTGDSAAAIYNRVK
                     GEKRIPLVRLPYMVEHTVEVKNGNLIIPHKDHYHNIKFAWFDDHTYKAPNGYTLEDLF
                     ATIKYYVEHPDERPHSNDGWGNASEHVLGKKDHSEDPNKNFKADEEPVEETPAEPEVP
                     QVETEKVEAQLKEAEVLLAKVTDSSLKANATETLAGLRNNLTLQIMDNNSIMAEAEKL
                     LALLKGSNPSSVSKEKIN"
     gene            86728..>87284
                     /locus_tag="VU534_000083"
     CDS             86728..>87284
                     /locus_tag="VU534_000083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HEU1512744.1"
                     /translation="MKINKKYLAGSVAVLALSVCSYELGRYQAGQDKKESNRVAYIDG
                     DQAGQKAENLTPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIISE
                     ELLMKDPNYQLKDSDIVNEIKGGYVIKVNGKYYVYLKDAAHADNIRTKEEIKRQKQER
                     SHNHNSRADNAVAAARAQGRYTTDDG"
BASE COUNT        27185 a        15408 c        19172 g        25519 t
ORIGIN      
        1 agccaaggtg tactgttata gattcaatta cactataatt tagtgtaatt gagaaaggag
       61 aaatgattgt gattgatgtt ggctaggtta tgttcaatga ttcctaccgt ctcaaatctt
      121 gtcagtaagg aaaaataaat tcttcaaaag tagagattac aaggcttgtt taagaaagaa
      181 ttcaaagacc ttgacaaata aaaataaaat ggttattata aaaaatggtc tgaaatagat
      241 gatgatactt ttcgaaaatc tcttcaaact acgtcagctc agctttgcct tgctgtgttt
      301 tgagcaagct acggttagct tccgagtttg attttcattt actagaaatg aaactgatga
      361 gagatatcag tagacatttg agtcaggata ttatggaaaa tgataaaaag agctcgtgag
      421 attggcatat cagactacta aagtattgag tttgttagga ttttagcgac tagttagctg
      481 ggaaaggaag atatttgtga caaataataa actgtattcg ttgatagaat ttagaaataa
      541 aatatatgaa gaattagaac tttccagaag tgatttagcg attttactat gtgccatgct
      601 tatcgcctct atcggattaa atatggattc gactcccgtg attattggag ccatgttaat
      661 ctctcctttg atgacaccta ttctgggagt ggggctctct ctagctatat ttgattttaa
      721 attgttaaga aaatctttta aaatattagc tattcaaatt cttgccagtc taatagcttc
      781 aacactttat ttttatcttt ctcccatttc gtatgctagt tcggagattg ttgctagaac
      841 ctctccgact atttgggatg ttctcattgc ttttgtagga gggatagcag gtatcattgg
      901 tgctaggaaa aaagagacca ataatattgt tcctggtgtt gctattgcaa ccgccttgat
      961 gcctcctctt tgtacagtag gttatgctat tgcttctgct aatctaaaat ttatcatagg
     1021 ctcctcttac ctattcctca tcaattgtag ctttattgtc attgcgactt atataggtgt
     1081 taggttgatg atggttaaga aacattattt taaagataat gaagaagact ctaaaatgcg
     1141 taggattttg cttctagttg ctgttttgct gatgattccg agtttcatct ctgcaacgac
     1201 tttagtgaga gaaacgttga aaaaagagtc ccttaagaaa tttatatcag agcagtttca
     1261 ggggtataat attttgaaaa aaacctattc taaaaagact cataccctaa agctaaccat
     1321 ttcaggaaat tatttgacag aagaagaact cgatatgatt tcaagtaaga gaggtgacta
     1381 tggtttaagt gatgtttctg ttcaagtttc acaattgtct gattcagaac aacttagtaa
     1441 ggaagagctg gtggagtatt tcttccagta tatcaaggat aaggaagcaa aagaaaagga
     1501 gaaagccaat aaatttgata cagagtctga ggagcaataa tttcttgaga atagctggtt
     1561 tctctcgtga gtcttctatg tatatcaaag gaagactgag gttttaagta taaaactttt
     1621 cttctattat agtagctaag tcttgacagg gttcaaaaaa tggtttacac tttataaagt
     1681 ttattacttt gaaaaggtgt gatactgtgg ctacggcaac aaaaaagaaa aaatcaacag
     1741 ttaaaaaaaa tctagtcatc gtggagtcgc ctgctaaggc caagacgatt gaaaaatatc
     1801 taggcagaaa ctacaaggtt ttagccagtg tcgggcatat ccgtgatttg aagaaatcca
     1861 gtatgtccgt cgatattgaa aataattatg aaccgcaata tattaatatc cgaggaaaag
     1921 gccctcttat caatgacttg aaaaaagaag ctaaaaaagc taataaagtt tttctcgcga
     1981 gtgacccgga ccgtgaagga gaagcgattt cttggcattt ggcccatatt ctcaacttgg
     2041 atgaaaatga tgccaaccgt gtggtcttca atgaaatcac caaggatgca gtcaaaaatg
     2101 cttttaaaga acctcgtaag atcgatatgg acttggtcga tgcccaacaa gctcgtcgga
     2161 tcttggatcg cttggtaggg tattcgattt cgcctatttt gtggaagaag gtcaagaagg
     2221 gcttgtcagc aggtcgcgtt cagtccattg cccttaaact catcattgac cgtgaaaatg
     2281 aaatcaatgc cttccagcca gaagaatact ggacagttga tgctgtcttt aaaaagggaa
     2341 ccaaacaatt tcatgcttcc ttctatggag tagatggtaa aaagatgaaa ctgaccagca
     2401 ataacgaagt caaggaagtc ttgtctcgtc tgacgagtaa agacttttca gtagatcagg
     2461 tggataagaa agagcgcaag cgcaatgctc ctttacccta taccacttca tctatgcaga
     2521 tggatgctgc caataaaatc aatttccgta ctcgaaaaac catgatggtt gcccaacagc
     2581 tctatgaagg aattaatatc ggttctggtg ttcaaggttt gattacctat atgcgtaccg
     2641 attcgactcg tatcagtcct gtagcgcaaa atgaggcggc aagcttcatt acggatcgtt
     2701 ttggtagcaa gtattctaag cacggtagca aggtcaaaaa cgcatcaggt gctcaggatg
     2761 cccatgaggc tattcgtccg tcaagtgtct ttaatacacc agaaagcatc gctaagtatc
     2821 tggacaagga tcagcttaag ctatataccc ttatctggaa tcgttttgtg gctagccaga
     2881 tgacagcggc cgtttttgat accatggctg ttaaattgtc tcaaaaaggg gttcaatttg
     2941 ctgccaatgg tagtcaggtt aagtttgatg gttatcttgc catttataat gattctgaca
     3001 agaataagat gttaccggac atggttgttg gagatgtggt caaacaggtc aatagcaaac
     3061 cagagcaaca tttcacccaa ccgcctgccc gttattctga agcaacactg attaaaacct
     3121 tagaggaaaa tggggttgga cgtccatcaa cctacgcgcc aaccattgaa accattcaga
     3181 aacgttatta tgttcgcctg gcagccaaac gttttgaacc gacagagttg ggagaaattg
     3241 tcaataagct catcgttgaa tatttcccag atatcgtaaa cgtgaccttc acagctgaaa
     3301 tggaaggtaa actggatgat gtcgaagttg gaaaagagca gtggcgacgg gtcattgatg
     3361 ccttttacaa accattctct aaagaagttg ccaaggctga agaagaaatg gaaaaaatcc
     3421 agattaagga tgaaccagct ggatttgact gtgaagtgtg tggcagtcca atggtcatta
     3481 aacttggtcg ttttggtaaa ttctacgctt gtagcaattt cccagattgc cgtcataccc
     3541 aagcaatcgt gaaagagatt ggtgttgagt gtccaagctg tcatcaggga caaattattg
     3601 agcgaaaaac caagcgtaat cgcctattct atggttgcaa tcgctatcca gaatgtgaat
     3661 ttacctcttg ggacaagcct gttggtcgtg actgtccaaa atgtggcaac ttcctcatgg
     3721 agaaaaaagt ccgtggtggt ggcaagcagg ttgtttgtag caaaggcgac tacgaggaag
     3781 aaaagattaa ataagaggag gggcccgaaa gtaaatttca ggctcctttt ggttagaact
     3841 tgacaaaaaa catcatttta tgcgaaacta gaagaagatt attttatact caatgagaat
     3901 caaagagcaa attagaaagc tagtcgcagg ttgctcaaag cactactttg aggttgaaga
     3961 tggaagctga cctggtttga agagattttc gaagagtatt aactaggaga agttatgcgt
     4021 attatctatc taattattgg ttttttatcg ctgaccttgg ctattgttgg ggttgtttta
     4081 cccttgttgc ctacaacacc tttccttttg ttgtctattg cttgtttctc cagaagttcc
     4141 aagcgattcg aagattggct ttatcatacc aagctctatc aagcatatgt agctgatttt
     4201 cgtgagacca agtctattgc gcgtgaacga aagaaaaaaa tcatcgtctc tatctacgtc
     4261 ttgatgggaa tttctattta ttttgcacct cttttaccag tcaaaatcgg tctgggtgct
     4321 ttgaccatct ttattactta ttatctcttc aaggtcattc cagacaaaga atagttaaaa
     4381 cagtagttat ttgccttgat aaaattgaaa gcatattcat aacaatatga tataataaaa
     4441 ttgaagtaat attcaaggag aatcaaatga tttacgaatt ttgtgctgaa aatgtgactt
     4501 tacttgaaaa agcgatgcag gctggagctc gtcggattga actctgtgat aatctagcag
     4561 ttggtgggac aacacccagc tatggagtga ctaaggcagc ggttgaactg gcagctaact
     4621 acgatacaac catcatgacc atgattcggc cacgtggtgg tgactttgtc tataatgacc
     4681 tagaaattgc tatcatgcta gaagacattc gtttgactgc tcaggctgga agtcaagggg
     4741 ttgtatttgg agctttaact gctgataaaa agttggataa gcctaatctg gaaaagttaa
     4801 ttgctgcatc aaaaggaatg gaaattgtct ttcacatggc ctttgatgaa ctaagtgatg
     4861 aagatcaagc ggaagctatt gactggctca gtcaagccgg tgtcactcgt atcctaactc
     4921 gtgctggtgt gtctggcgac tccttagaaa aacgttttgt tcactatcac agaattttgg
     4981 agtacgctaa aggtaaaatt gaaattctac caggtggggg gattgacctt gaaaaccgtc
     5041 aaacctttat cgaccaggtg ggggtaacac aattgcatgg tactaaggtt gttttttaaa
     5101 aaatagaaag gaactgctag ctttgggtag cagttttcac ttatgtttga aatttttaaa
     5161 tcctatcaat ttaatcaaga aaaggctcat gattatggtt ttatagaaaa tagcgaagtc
     5221 tggacatata gttgccagat tttgcaaggt gactttgtca tgactgtgtc catcactgct
     5281 gataatgtga actttcaagt ctttgaccaa gagactggtg acctctatcc tcacgtttat
     5341 atggaaagca tgaggggaag ttttgtcgga aatgtccgtg aggcttgtct ggagattctt
     5401 taccagattc ggaaggcttg ttttgatgtg caagatttta tctgtcatca gactaagcgt
     5461 atcatgactc aagttcagga aaagtatgga aaccagttgg agtatctgtg ggaaaaatcg
     5521 cctgatacag ctgtattgcg ccatgaaggc aatcaaaagt ggtatgccgt cttgatgaaa
     5581 atctcttgga ataagctgga aaagggcaga gaaggacaag tggaagcagt caacctcaag
     5641 catgaccaag tagctaattt gctttcacaa aaggggattt atccagcctt ccatatgagc
     5701 aagcgctact ggattagtgt gtcccttgat gatactttat cagatgaaga agtactggaa
     5761 ttgatagaaa aaagttggaa cttaacctct aaaaaatgaa atattttaat aattttcatg
     5821 aactttcaat tagctaaata ttctttactg aagagatttt tagaaaatat aggatttacc
     5881 acactagagg aatatggtgc catcttcaaa tacctgattg agaatgtcaa gacggatcgt
     5941 cagatcatct attcgcctca ctgtcatgat gacctcggaa tggcagtggc aaatagcctt
     6001 gctgctgtca agaatggtgc aggacgtgtt gaagggacta tcaatggtat tagggagcga
     6061 gctgaaaatg ctgctttgga agaaattgca gtggctctca atattcgcca agattactac
     6121 caagtagaaa ccagtattgt cctaaatgag accatcaata cgtcagaaat ggtttctcgc
     6181 ttctctggta ttccagttcc taaaaacaaa gccgtcgttg gtggcaatac cttctcccac
     6241 gaatctggta ttcaccaaga tggagtcctt aaaaatcctc tcacttatga gatcatcaca
     6301 cctgaattgg ttggtgttaa gattctgctt ggaaaattat ctggtcgcca tgcttttgtt
     6361 gagaaactga gagaattggc cctagatttt acagaagagg atatcaaacc actctttgct
     6421 aagttcaagg cactggtcga taagaagcaa gaaatcacag atgcagatat tcgagctttg
     6481 gtagctggaa ccatggttga aaatccagaa ggcttccact ttgatgattt acaacttcaa
     6541 actcatgcag ataatgacat tgaagcgctc gttagcctag ccaatatgga tggtgagaaa
     6601 gtcgaattta atgcgacagg gcaaggttcc gttgaagcaa tctttaatgc tatcgataag
     6661 ttctttaacc aatctgttcg tttggtgtcc tacactatcg atgcggtaac agatggaatc
     6721 gatacccagg atcgggtttt ggtcactgtt gaaaacagag atacagaaac catctttaat
     6781 gcagcagggc ttgattttga tgtgttgaag gcttctgcta ttgtctatat aaacgctaat
     6841 acctttgttc aaaaagagaa tgcaggtgag atgggacgca gtgtttctta ccacgatatg
     6901 cctagtgtgt aaaggagaag gctatggcaa agaaaatagt agctctagca ggagacggaa
     6961 ttggcccaga aatcatggag gttggtttag aagttctgga ggctctagct gaaaaaacag
     7021 gttttgacta tgagattgac agacgaccgt tcggaggtgc agatattgat gcagcatgac
     7081 ctcccttacc tgatgaaacc cttaaggcaa gtagggaagc agatgctatc ctactagtag
     7141 ctatcggtag tcctcagtat gatggagcag tggttcgccc tgaacaaggc ctgatggctc
     7201 tccgtaagga actcaatctt tacgctaata ttcgtcctgt aaaaatcttt gacagtctca
     7261 agcatttgtc accactcaaa ctggaacgaa ttgctggtgt agactttgtc gtggtgcgtg
     7321 aattgacagg cgggatttac tttggatatc atattcttga agagcgcaat gcgcgtgata
     7381 tcaacgacta tagctatgag gaagtggagc ggattattcg caaagccttt gaaattgcaa
     7441 gaaatcgcag aaaaatcgtt actagtatcg ataagcaaaa tgttctagcg acctcaaaac
     7501 tctggcggaa agtagctgag gaagtcgcac aggatttccc agatgtaacc ttggaacatc
     7561 agctggtaga ctcagctgct atgcttatga ttaccaatcc tgctaagttt gatgttattg
     7621 taacggagaa tctttttgga gatattttat ctgatgaatc aagcgtctta tctggtacac
     7681 ttggggttat gccatcagcc agtcattctg aaaatggacc aagtctctat gaacctattc
     7741 acggttcagc acctgatatt gcaggtcaag gaattgccaa tcctatttcc atgattttat
     7801 cagtttccat gatgttgaga gatagtttcg gacgttatga ggatgcagag cgtatcaaac
     7861 gtgctgttga gacaagtctg gcggcaggaa ttttaacgag agatatagga ggtcaggctt
     7921 caacaaagga aatgacggaa gctattattg caaggttatg aagttagacg aaaaaattac
     7981 tctagtcctt ttgatttgga atgtcatcat tttcttgatt tatggtattg acaaatctaa
     8041 ggcaaggaga agagtttggc gcatccctga gaaaatctta cttattttag cctttacttt
     8101 tggtggtttt ggtgcctggc tagcaggaat catctttcac cacaagactc gaaaatggta
     8161 ctttaaaata gtttggtttc ttgggatggt gaccacacta gtagccttat attttatttg
     8221 gaggtaatgg atggcagggt cttcgaggga atacgctgct tgggctctag cggactatgg
     8281 ttttaaggtc gtgattgcag gatctttcgg tgacattcat tacaataatg aactcaataa
     8341 tggcatgttg ccaatcgttc agcctagaga ggttagagag aaactagccc agctaaaacc
     8401 aaccgaccag gtaactgtgg acttggaaca acaaaaaatc atctcaccag ttgaagaatt
     8461 caccttcgag atagatagcg agtggaaaca taaactccta aatagtttgg atgatatcgg
     8521 tattaccttg cagtatgaag agttgattgc tgcttatgaa aaacaacgac cagcctactg
     8581 gcaggattag aaaaaataga aaaggagata tagtaaactg aaataagatg taaacaaatg
     8641 aattggagct taacatccat ttccagcaat tttttagaaa ctacagtgga ctattctgga
     8701 ttcaacacat tataaaatta tgacaaaaca cattcacaag aaggctacga cattttaaaa
     8761 ggtgagggcg gatgtatcgt ttgccctact aaagttggtt acattatcat gaccagtgac
     8821 aaggcaggac ttgagcgtaa gttcgcagcc aaagaacgta agcgtaacaa accaggtgtt
     8881 gttctctgcg gtagcatgga tgaactttgc gctttagcgc aactcaaccc agaaattgaa
     8941 gcattctact aaaaacattg ggatgaagat attcttcttg gttgtatcct tccttggaaa
     9001 ccagaagcct ttgaaaaact caaagcatac ggggatggcc gtgaagaact tattactgat
     9061 gtacgtggta ctagctgttt tgttatcaag tttggaaaag caggtgaaca attggctgcc
     9121 aagctttggg aagaaggtaa aatggtctac gcctcatctg cttcaatgac aaaacgattg
     9181 aaactcgcta tgagcaaggt gtaatggtgt ctatggtcga taaggacggc aaactcatcc
     9241 cagaacaagg aggagcacgt tcaacttcac cagctccagt tgtgatccgt aaagggcttg
     9301 acattgataa aatcatgatg cacctgtcag atacttttaa ctcatgggac taccgtcagg
     9361 ttgagtatta ttaggataga gaagaagtct agtgttatga gatattaaag ctcctaacac
     9421 tgggcttttg tttagaattt cttttctttt tctataggat atggtattct atgtagaaaa
     9481 tatatgttaa taagtaatgc caatatttaa acatcattag taaaaggagt tagattgatg
     9541 aataaaagaa aagttagttt agaagatttt tataaatggt atagtctaaa taaagaagag
     9601 ttattaaata aggcaactgt tggtgaaaag tttaatgata aattaaaaga agagtttctc
     9661 caggaatggc ctttggatag gattttaaca atgtcaatcg atgaatatgt aataggaaag
     9721 ggacagcaaa ataagtcttt atgctacgct cttgagaagg gaaaatacaa aaatctattt
     9781 cttggaattt ctggtggctc agcttcaaaa tttggtattt attggaataa aaaaacaaac
     9841 aaatataaag atcaagctaa taatgagatt tcagagttgg atcagcgatt ttcaaaatta
     9901 aaatcagatt tgtatgaaat tatcaaagaa ggtattcgtt ttaactttga aaatcctatt
     9961 tttgatatga aaagatcaac aaatgaattt attggtcgtt ctgctatggt gacaaaatta
    10021 ctttgtatct atactgaggg agatcctttc tttggtgtaa atattaatag tcagaaagaa
    10081 ttttggaacc actttgtttc tcagacaaat caaggtggac cttatctgca aaatcataaa
    10141 ataattgaac tggtgtccaa aacttatcct gagttggagc catcgaaatt aggaactatg
    10201 ctttttgagt attctaagct ttttatggaa aataaggaag acaatagtac aatggattca
    10261 tcaaacaatt ttcgtcatca attaactcaa tctctattaa agtctccaaa cctcatcctc
    10321 cgcggtgctc ctggcacggg aaaaacttat cttgctaaag aaattgctaa agaattaacg
    10381 gatggcaacg aagatcaaat cggatttgta caatttcacc catcatatga ttatacggat
    10441 tttgtagaag gtttaagacc agtatcaaat ggggatggag ctattgagtt taggctacag
    10501 gacggtattt ttaaagattt ttgtcagaaa gcaaaagaaa cccaattgat tggaggacaa
    10561 gataattttg atgaggcttg ggattcttac ttagaatata taaatgttgc tgaagaaaaa
    10621 gaatatataa caaaaacatc ttacttatct gttaatagta gacaaaattt gtcagtaaat
    10681 tatgatagtg gtgttccagg atggtcacta cctagcaaat atgtttacga gttgtataaa
    10741 gataaaaatt ataataagca agaatactac aaaagtggtg gaaaaactgt cctagaaaca
    10801 ttgagaaaga gatttggttt gaaagactat gtttccccaa cagaaattga tactgataag
    10861 aattttgtct tcatcatcga tgagatcaat cgtggggaga tttctaagat ttttggcgaa
    10921 ctctttttct ctatcgaccc cggctatcgt ggtgaaaaag gaagtgtttc tacccaatat
    10981 gcaaatctac acgaaactga tgaaaagttc tatatccccg aaaatgttta catcatcgga
    11041 actatgaatg atattgatcg ttcagtggat acctttgatt ttgctatgcg tcgtcgtttt
    11101 cgttttgttg aagttactgt cgagggtcaa gctggcatgt tggataaaga gttgaatatc
    11161 catgcagaag aagcaaaaat tcgtctaaga aacttgaacg ctgctatcga aaatattcag
    11221 gaattaaaca gtcattatca tattggacca agttattttc ttaagttgaa ggatgtagat
    11281 tttgactatg aattactctg gtctgattat attaagcctc tcctagaaga ctacttgcga
    11341 ggttcttatg atgaggttga aactttggaa actttgaaaa aagcatttga tctgacaaat
    11401 aatgagcaaa aagatcagac agtagctgat gacaatgaag gcgatgaaaa cgatgatgcg
    11461 gattactgat aatcaacaca agattattaa agaaaaattt gttgaagaat atcctaaact
    11521 aagcaatcct cttttagaca gaaccttgga aagtctatcc caagatgaac gtattttcat
    11581 ttttccaaat gatttgactc atactcctga tttggataag gaccaaaaga tttttgaaac
    11641 agtcaatcag aaaatcaaga cagggaacgt gattggtttt cttggatatg gtcaggaaag
    11701 attaacgatt tcctcacgat tttctgatga gagtaatgac cactttttgc attatctctt
    11761 aaacaaggtt cttcatatca atctcactag tttagatgtt gctttgtctc gtgaagagag
    11821 gctttatcaa cttttggtgt atctctttcc caagtatcta caagctgcta ttcgaaaagg
    11881 tctttataag gaatatcatc gattttctca taacgacagt catgttaagg gagtgattga
    11941 tgtaagaaac catctcaaga aaaatcttcc tttcacggga aatattgcct acgcaacgag
    12001 agagttcacc tatgataatc ccctcatgca gttggtccgt cacactattg aatacattaa
    12061 gaatcagaaa agcattggtc aaggggtact agataatctc tcaactagtc gtgaaaacgt
    12121 atctgaaatc gtgcgtgtaa cgccctctta taaactagct gatcgtgcta agattattcg
    12181 gggaaatcaa tctaaaccta tacgtcatgc atactttcac gagtacagaa acttacaaga
    12241 actttgtctg atgatcctaa accaagaaaa gcacggttta gggtatcaag atcaaaaaat
    12301 ctatggtatt ctctttgatg ttgcctggct ttgggaagag tatgtttaca ccttgttgcc
    12361 aaaaggtttt gtacatccca gaaataagga taagacggat ggaatttcag tattttctgt
    12421 tgggaaacga aaagtatatc cagattttta tgacagagaa cgaaagattg ttctagatgc
    12481 aaaatataaa aaactggaat tgactgaaaa aggaatcaac cgtgaggact tattccagct
    12541 gatttcctat tcttatattt taaaagctga gaaggctgga ctgatttttc ctagtatgga
    12601 gcagtcagta aatagtgaaa taggaaaagt agctggctat ggagctcaat tgaagaagtg
    12661 gtctattcga atccctcaga atgcctcatt ctatagtaca ttttgtaaaa tgatggaaaa
    12721 ttcagaagaa aattttaaag cgattattga tgaagaagtg gggagaaaat aatttcccct
    12781 ctttctttta tttttaacac aagtaaaacc cgaacgatat attttaattc ataaaataat
    12841 ttgacaaaaa ctgtactttg atttataata aattaaggaa acgtcggaaa aggcgtagtg
    12901 atgcaagagc ataggtaggt cattacaaaa gaaacgagac atcgatatgt taaatgaatt
    12961 tccaattttt gattacgaag atattcaatt gattccaaat aaatgtgtca ttaaaagccg
    13021 tgcagaagcg gatacaagtg tcactttagg aaatcacacc tttaaactac ctgttgtgcc
    13081 agcgaatatg cagacgattt tggatgaaaa tgtagcagag caactggcta aaggtggtta
    13141 cttctacatt atgcaccgtt ttgatgaggc aggacgcatt ccttttatta aacgaatgca
    13201 caatcaaggg ctcattgctt ctatctctgt cggtgttaag gattatgagt atgattttgt
    13261 tagccagctc aaggctgata ctcctgagta tatcactatt gatattgctc atggtcatgc
    13321 ggatagcgtg atttctatga ttcaacacat caagaaagaa ttgccagata cctttgtcat
    13381 tgctggaaat gtgggaacac cagaagctgt gcgtgaattg gaaaatgctg gtgcggatgc
    13441 tactaaggtc ggaatcggtc ctggtaaggt ttgtatcacc aaggttaaga ctggttttgg
    13501 tacaggtggt tggcagttgg ctgctctacg ctggtgtgcc aaggctgcgc gtaaaccgat
    13561 tatcgctgat ggaggaattc gtactcacgg tgatattgct aagtctatcc gcttcggtgc
    13621 tagcatgatc atgattggtt ccctctttgc aggacacatt gaaagtccag ggaaaacgat
    13681 tgaagtcgat ggtgaacagt tcaaagaata ttatggttca gcctcacaat atcaaaaagg
    13741 tgcttacaaa aatgtggaag gcaaacgtat cttgcttcct gctaaaggtc atctgcaaga
    13801 cactttaact gagatggaac aagaccttca aagtgctatt tcttatgcag gtggacgtca
    13861 ggttgctgac cttaaacacg ttgattatgt gatcgtgaaa aactccatct ggaatgggga
    13921 tgcttcccac taagacgggg tctttgacca aaaaacttgt tattagagca aatttctgtt
    13981 ataataaaac aagtttccac ccttagtgta atggatatca cgtaagattc cggttcttga
    14041 gatgggggtt cgattccctc agggtggatg taaacatcct aaaaagcctt taatagggct
    14101 tttttcttta tcctgaccca aatttgccgc taaaactgag aatctctgtc taaagaattc
    14161 ccaaatgctt tccagtcccg ttttagagtg actcaggggg ctttttttga tataataaaa
    14221 aggactatta tcagttagaa agaggttggt atgaaagaat tacaaactgt actaaagaat
    14281 cattttgcaa tcgaatttgc agacaaaaag ttactggaaa ctgcctttac tcatacgagt
    14341 tatgccaatg agcaccgcct cttaaaaatt tcacacaatg aacgcttgga atttttagga
    14401 gacgctgttc tacagttatt gatttcagaa tatctatata aaaaatatcc taaaaagcct
    14461 gaaggtgacc tatcaaaact ccgtgctatg attgtccgtg aggagagttt agctggtttt
    14521 gcgcgtgatt gccagtttga ccagtttatc aagttgggta aaggggaaga aaaatcaggt
    14581 ggtcgcaatc gtgacaccat tcttggtgat gcctttgaag cctttcttgg tgcccttctt
    14641 ttggataagg atgtggccaa ggtcaaggaa tttatctatc aagtcatgat tcctaaggtt
    14701 gaagcaggcg agtttgagat gattacagac tataaaaccc atctccaaga gttgcttcag
    14761 atcaatggtg atgtggctat tcgttatcag gtgatttctg aaacagggcc tgctcacgat
    14821 aaggtttttg atgtagaagt tcttgttgaa ggtaagagca tcggtcaagg ccaaggtcgt
    14881 tctaagaaat tagcagagca ggaagctgcc aaaaatgccg ttgagaaggg gctggattca
    14941 tgtatttaaa ggaaatcgaa attcaggggt tcaagtcttt tgctgataag accaaggtcg
    15001 tttttgacca aggtgtgacg gcagttgttg gacccaatgg atctggaaag tccaatatta
    15061 cagaaagtct gcgttgggct ttgggggagt ctagtgtcaa gagtctccgt gggggcaaga
    15121 tgccggatgt catctttgct ggaaccgaaa gtcgcaaacc gctcaattat gcttctgtag
    15181 ttgtgactct ggataatcat gacggattta tcaaggatgc aggtcaagaa atcagggtgg
    15241 aacgccatgt ctatcgtagt ggagatagcg aatacaagat tgacggcaag aaagtccgtc
    15301 tgcgtgatat tcatgacctc ttcttggata ctggattggg acgagattcc ttctctatta
    15361 tttcccaagg gaaggttgag gagattttta attccaagcc tgaggaacga cgagctattt
    15421 ttgaagaagc tgctggagtt ttaaaataca agactcgcag aaaagaaacc gagagtaaac
    15481 tgcagcaaac tcaggataat ctggaccgct tagaggacat tatctacgag ttggataatc
    15541 aaatcaagcc tcttgagaag caagctgaga atgcccgtaa gtttttagac ttggaaggac
    15601 aacgtaaggc tatttattta gatgttctgg ttgctcaaat caaggaaaat aaggctgaac
    15661 tagagtcgac agaagaagag ttgactcagg ttcaagaact cttgatgagt tattaccaaa
    15721 agcgtgaaaa attagaagaa gaaaatcaaa ctcttaaaaa gcaacgccaa gatttacagg
    15781 ctgaaatggc caaagaccaa ggcagtttga tggacttgac tagtctgatt agtgatttag
    15841 aaagaaaatt agccctatcg aaactggagt ccgagcaagt ggccttgaat caacaggagg
    15901 cacaagcccg tttggctgct ttggaggata agagaaattc actcagcaaa gaaaagtctg
    15961 ataaagaaag ctctttagct ctgttagagg gaaatctagt ccaaaataat caaaaactca
    16021 atcgtttaga agctgaattg ctggctttct cagacgatcc tgatcagatg attgagctct
    16081 tacgtgaacg ctttgtagct cttttacaag aagaagcgga tgtctcaaac cagttgaccc
    16141 gtattgagaa tgagttggaa aatagtcgtc agctttctca aaaacaagca gatcaactag
    16201 aaaagctgaa agagcaatta gctatagcta aagagaaggc tagtcagcaa aaggaagagc
    16261 ttgaaactgc caaggagcag gttcagaaat tattggctga ctaccaagct attgccaagg
    16321 agcaagagga gcagaaaact tcctatcaag ctcaacaaag ccaactcttt gaccgtctgg
    16381 ataatctcaa aaacaagcag gccagagctc aaagtttgga aaatatcctg agaaatcata
    16441 gtaactttta tgcaggtgtt aagagtgttc tccaagaaaa agatcgccta ggtgggatta
    16501 ttggtgcagt cagtgagcat ctgacctttg atgtttatta tcaaactgcc ctagagattg
    16561 ccttaggggc aagtagccag catatcatcg tagaagatga agagtcggca accaaggcta
    16621 ttgacttcct taaacggaac agagccggtc gtgcaacctt tcttcctttg accactatca
    16681 aggcgcgtac gatttctagt cagaaccaag atgctatcgc tgtaagccca ggtttccttg
    16741 ggatggcaga tgagttggtg acttttgata ctagactgga agccattttc aagaacttgc
    16801 tagctacgac ggctatcttt gataccgtag aacatgcgcg tgcagcagct cgccaagttc
    16861 gttatcaggt tcgtatggtg acattggatg ggacagagtt gcgcacaggt ggttcttatg
    16921 caggtggtgc caatcgccag aataacagca tttttatcaa gccagaactg gagcaattac
    16981 aaaaagaaat tgctgaagaa gaagcaagct tgggttcaga agaggcgact ttgaagacct
    17041 tgcaagatga gatggccaga ttgaccgagt cattagaagc tattaaatct caaggagagc
    17101 aggcacgtat tcaggagcaa ggcttgttcc tcgcttatca gcaaactagt cagcaagttg
    17161 aagaactgga aactctttgg aaactccaag aagaggaaat agatcgtctt tccgagggag
    17221 attggcaagc ggataaggaa aactgccaag agcgtcttgc tgcaatctcc agtgacaagc
    17281 aaaatctgga agctgagatt gaagagatta agtctaacaa aaatgccatc caagaacgct
    17341 atcaaaactt gcaggaagag ctagcgcaag ctcgtttgct taagacagaa ctgcaagggc
    17401 aaaaacgtta tgaagttgct gatattgaac gcttaggcaa ggaattggac aatcttgatt
    17461 ttgaacaaga ggaaatccag cgccttcttc aagaaaagat tgataatctt gagaaggttg
    17521 atacagaatt gctcagtcaa caggcggaag aatccaaaac tcaaaaaaca aatctccaac
    17581 aaggtttgat tcgcaagcag tttgagttgg atgatattga gggtcaactg gatgatattg
    17641 ctagtcattt ggatcaggct cgccagcaga atgaagagtg gattcgcaag caaactcgtg
    17701 ctgaagccaa gaaagaaaag gttagcgagc gcttgcgcca tctacaaagt caattaacag
    17761 accagtacca gatcagctac acagaagctt tagaaaaggc gcatgagttg gaaaatctca
    17821 atctggcaga gcaagaagtt aaggatttag agaaggctat acgctcactg ggtcctgtca
    17881 atttagacgc tattgaacag tacgaagaag ttcacaaccg tctggatttc ctaaatagcc
    17941 aacgtgatga tattttgtct gcgaaaaacc tgctccttga gaccattaca gagatgaatg
    18001 atgaggtcaa ggaacgcttt aaatcaacct ttgaggtcat tcgtgagtcc tttaaagtga
    18061 ccttcaagca gatgtttggt ggaggtcagg ctgacctcat tttgactgaa ggagacttgc
    18121 tgacagctgg ggttgaaatt tctgtccaac caccaggcaa gaaaatccag tctcttaatc
    18181 tcatgagtgg tggtgaaaaa gccctatcgg ctcttgcctt gctcttctcc attattcgtg
    18241 tcaagactat tccatttgtt atcttggatg aggtggaagc tgcgctggat gaagccaatg
    18301 ttaaacgttt tggggattac ctcaaccgct ttgacaagga cagccagttc atcgtcgtaa
    18361 cccaccgtaa gggaaccatg gcagcggctg attccatcta tggagtgacc atgcaagaat
    18421 cgggtgtttc aaagattgtt tcagttaagt taaaagattt agaaagtatt gaaggatgac
    18481 aattaaacta gtagcaacgg atatggacgg aaccttccta gatgggaatg gacgctttga
    18541 tatggatcgt ctcaagtctc tcttggtttc ctacaaggaa aaagggattt actttgcggt
    18601 agcttcgggt cggggatttc tgtctctaga aaaattattt gctggtgttc gtgatgacat
    18661 tattttcatc gcggaaaatg gcagtttggt agagtatcaa ggtcaggact tgtatgaagc
    18721 gactatgtct cgtgactttt atctggcaac ttttgaaaag ctgaaaactt caccttatgt
    18781 agatatcaat aaactgctct tgacgggtaa gaagggttca tatgttctag atacggttga
    18841 tgagacctat ttgaaagtga gtcagcacta taatgaaaat atccaaaaag tagcgagttt
    18901 ggaagatatc acagatgaca ttttcaaatt tacaaccaac ttcacagaag aaacgctgga
    18961 agatggggag gcttgggtaa acgaaaacgt tcctggtgtt aaggccatga caactggctt
    19021 tgaatccatt gatattgttc tggactatgt cgataaggga gtggccattg ttgaattagt
    19081 taaaaaactt ggtatcacaa tggatcaggt catggctttt ggagacaatc ttaatgactt
    19141 acatatgatg caggttgtgg gacatcctgt agctcctgaa aatgcacgac ctgaaatttt
    19201 agaattagca aagactgtga ttggtcacca taaggaacgg tcggttatag cttatatgga
    19261 gggcttataa tggcagatat aaaattgatt gcattggact tggacgggac cttgctgact
    19321 actgataaaa ggctgacgga tcgtaccaag gaaaccttgc aagctgcgcg tgatcgtggt
    19381 atcaaggtcg tattgacaac tggtcgtccc ttaaaagcca tggatttctt tctccatgag
    19441 ttagggactg acggtcagga agatgagtat accattactt ttaatggtgg attagttcag
    19501 aaaaatacag gagaaatcct tgataaaaca gtcttttcat atgatgatgt ggcacgtttg
    19561 tatgaagaaa cagagaaatt atcactgcct cttgatgcca tctcagaagg aacagtttat
    19621 caaatccaat cggaccaaga aagtctttat gccaaattca atccagcttt gacctttgtt
    19681 ccagtggact ttgaagactt atctagtcaa atgacctaca acaaatgcgt gactgccttt
    19741 gctcaagaac ccttggatgc agccattcag aagatttctc cagaattgtt tgaccaatat
    19801 gaaatcttta aatcacgtga aatgttgcta gaatggtcac caaagaatgt tcataaagca
    19861 acaggtttgg caaaactaat cagccatctt ggaatcgacc aaagtcaagt gatggcttgt
    19921 ggtgacgagg ccaatgacct ctctatgatt gaatgggcag gtcttggtgt tgctatgcaa
    19981 aacgctgttc ctgaagtaaa ggcagccgca aatgtagtga cgccgatgac caacgatgag
    20041 gaagctgtcg cctgggctat cgaagaatat gtgctaaagg agaactaaga tatgggattg
    20101 tttgaccgtc tattcggaaa aaaagaagaa cctaaaatcg aagaagttgt aaaagaagct
    20161 ctggaaaatc ttgatttgtc tgaagatgtt gatcctacct tcacagaagt tgaggaagtt
    20221 tctcaggaag aagcagaggt tgaaattgtt gaacaagctg tgttccaaga agaggaaatc
    20281 caagacacag ttgaagaaag tcaggattca gagccagctg taggggtttc tcaagaagaa
    20341 atagaagaat taccaaactc agaagaatta ccagaggaag agaagcttga gcacgaagga
    20401 actgtagaag aaaataattc tgaagtgctt gaaccagaag ctcctcaaac agaagaaact
    20461 gttcaggaaa aatatgaccg cagtcttaag aaaactcgca caggtttcgg tgcccgcttg
    20521 aatgccttct ttgctaactt ccgctctgtt gacgaagaat ttttcgagga actggaagaa
    20581 ctgctgatta tgagtgatgt tggtgtccaa gtcgcttcta acttaacgga ggaactacgt
    20641 tacgaagcca agcttgaaaa tgccaagaaa cctgatgtac ttcgtcgtgt catcattgag
    20701 aaattggttg agctttatga aaaggatggt agctacgatg aaagcatcca cttccaagat
    20761 aacttgacag ttatgctctt tgttggtgtg aatggtgttg ggaaaacaac ttctatcgga
    20821 aaactagccc accgctacaa acaagctggt aagaaggtca tgctggttgc agcagatacc
    20881 ttccgtgcgg gtgcagtagc tcagctagct gaatggggcc gacgagtaga tgttccagta
    20941 gtaactggac ctgaaaaagc tgatccagcc agcgtggtct ttgatggtat ggaacgtgcc
    21001 gtgactgaag gtatcgatat tctcatgatt gatactgctg gtcgtctgca aaataaggat
    21061 aaccttatgg ctgagttgga aaagattggt cgtattatca aacgtgttgt gccagaagca
    21121 ccacatgaaa ccttcttggc acttgatgca tcaacaggtc aaaatgccct agtacaggcc
    21181 aaagaatttt cgaaaatcac acctttaacg ggaattgttt tgactaagat tgatggaact
    21241 gctcgaggag gtgtggttct agccattcgt gaagaactca atattcctgt aaaattgatt
    21301 ggttttggtg aaaaaatcga tgatattgga gagtttaact cagaaaactt tatgaaaggt
    21361 ctcttggaag gtttaatcta atcagaagca aaaatcctgc aaggcataaa cttgcaggaa
    21421 atttttttat tctaagcgac catcttgacg ataggtgata tctggttgcc aagtccattt
    21481 ggcaccgaat ttttcaagta ggtcaaagct ggcttgaggt cccatgcttc cagctttata
    21541 gtcatgaagt ggggcaccat tttcagccca gagcttttca atacggtcaa tcaacttcca
    21601 tgacgcacaa acttcatccc agtggctaaa gttagttgag ttgttattta ggacatcata
    21661 aatcaatttt tcgtatggtt ctggagaagc accagttgca gtcgcatctg tacggtaatc
    21721 aagtgagtta ggagccaagt taaattcttc tcctacttgc ttcccattta ggctaagaga
    21781 gaagccttct gttggttgaa tatagatggt caaaatattt ggagcaagtg gttctccaaa
    21841 gatagaatcc atttgtttaa agacgatgtt gacatgagtt cctttttcag tcagtcgttt
    21901 acctgtacgg aaaaagaaag gaacaccacg gaatcgatcg ctgtctacaa agaaggcacc
    21961 agatgtaaag gtttcagttg ttgattctgg attcacattt ggctcgctac gataagagat
    22021 gtatttcatg ccatcaatct taccagagcg gtattgccca cggataaagt gttctttgag
    22081 ttcttcatca gttggatgat agaggttttt aaagacctta atcttttcag cacgaatctc
    22141 gtcttttgtg aagcttgctg gtttgtccat ggcgaggagc gaaagaagtt gtagagtgtg
    22201 gttttggacc atgtcacgga gggcaccgga ttggtcatag tagccaccac gttcttctac
    22261 acccaagcgc tccgcaaagg taatttgaac attgtcgata aaatccttgt tccaaacgtt
    22321 ttcaaaaatc aagtttgcaa agcgaactgc aaagatgctt tggatcattt ccttaccaag
    22381 ataatggtcg atacggaaaa tttgttcttc gtcaaatgtt gctaggagtt cgtcattcaa
    22441 cttgcttgca gttgcgtaat ctgtaccaaa tggtttttca acgatcaagc gctcaaaacc
    22501 tttgccatcg acaatgtttt cagatttgag gtgtttggca atggttccaa agaactgagg
    22561 tgccatagac aagaagaaga gcttattgtg ttcagcttgg tatttttcat taagctcagc
    22621 ttgtaattga cgcaaagcaa tataatgttc cgaatcattg acatcatggc tttgatagta
    22681 gaagtggcta gcaaattctt gggcttgctc ggtactatct gccaaatcaa ggatggactc
    22741 gacaactaca gattcaaaat attccttact ccaaggtcta cgggcagttc caataacggc
    22801 aaagtgcttg gaaagattgc cggattgata tagtctaaaa agggaagggt agagcttgcg
    22861 tttagccagg tctccactcg caccgaaaat tgtaacaata accttagatg acatctagct
    22921 acctaatttc tatttttatt cctagtcttg ctaggtatga ggaaacctca tttcataaac
    22981 ttaattctaa cataattttc cgaaaaatca aaaattccaa tacgaggtag aaaaactgca
    23041 aggaaatcct tacagtttga gtttagacgt ttaagacctt atctaagaac tctttcagac
    23101 gagggtgttg tgggttatca aagatttggt caggtgttcc gtcttcaagg aactcgccat
    23161 ctgcagtaaa gataacgcgg ttggcaacct gacgagcaaa tcccatctca tgggttacga
    23221 taatcatggt catgccttgc tcagccaatt ccttcataac gttaagtacg tctccaacca
    23281 tctcagggtc aagggcagaa gttggttcat cgaagagcat gatgtctgga ttcattgcta
    23341 ggccacgagc gatggccaca cgttgttttt gaccacctga taggctatct ggattggcat
    23401 tagctttatc tgctagtcca accttttcaa gcaactccat tcccaattcc tcagcttctt
    23461 ccttagtcat caacttgtgc tcaataggag caaaggtgat gttgtccaat acagacatat
    23521 gagggaagag gttgaagtgt tggaatacca tgccgatatt ttcacggacg tggtcaacat
    23581 tggttgtttt ttcagttaaa tcatagccgt tcacagtgat gtgaccgcta gtgacttctt
    23641 ctaaaagatt gaggctacgg aggaaagttg acttaccaga acctgaagga ccgatgatac
    23701 aaacaacatc tccttcatag aacttagtcg taattccttt taggacttca ttttttccat
    23761 agtgcttgtg taaatcattt acatcaattt ttaattttgc cattaacgaa tcctcttttc
    23821 taagcgtttc gctagtctag tcaaaagtgt gataattaca agatagaaga tagcaaggat
    23881 tgcatacatc ttgaaacttt ggtagttacg agcaatgata atcttaccag tttggaagag
    23941 ttcaaccaaa ccgatagcag atacgatagt tgtatcttta agagcgataa cgaattggtt
    24001 gacaaagttt ggcaacatca atttagttgc ttgtggcaag ataatcttac gcatggtttt
    24061 tccataagag atacccaagc ttcggctggc ttccatttgg ccaactggaa cggcctgaat
    24121 accaccacga acgatttcag cgatataagc agccgcattg agtgagaggg caatggttcc
    24181 agctacaaag tcgttaattg ggctttgttg gcctgtgata gactcgatga agtttggaat
    24241 tccccagaag atgaaggctg caagaatcat caatggaata ccacgaataa cgtcaacgaa
    24301 aatctcagag atgacgcgaa gagatttgta tgggctaacg ctaaacatac cgaagataat
    24361 tccgatgaca atggcaatag caaatgagat aagagctaga gcaagagtga taccaagacc
    24421 gctaaggagt tgtttgtagt tgttttgaag caagccccag agcgttgttt cgtcaacagt
    24481 acttgttgaa gcagttgaag attcgctagc taggtatttg tcaagaatct tttggaattc
    24541 accgtttgct ttaaggtttg caagtccgtt gttgaacatt tcaatcagtt ctggatttgc
    24601 tcctttttta acggcaaagg ctgtttcacc gattggagtt ccagagattg gagttttcaa
    24661 tttttgacct tggctgatag aatatttgag aacaggttca tcatccataa cggcatcaat
    24721 ggcaccagtg tttaaactgt catacattga agaaccatca gcaaaggttt tgattttgta
    24781 gccgtatttg ctttgatttt ctgttaggaa ggtttgagaa gcagttccgt ttttaacacc
    24841 gactgtcttt ccttttagat cttcataaga agcaatattg cttgattctt tgacaccaag
    24901 aatggtatta gcagtgtagt atgattctga gaagtcaaaa gttgccttac gagcatctgt
    24961 gacagacata ccagcgatga taccatcggc ttgaccagct tggacagcac tgatagcagc
    25021 atcaaaacca gggttggtga tttcaatttc aaaaccttgg tctttagcga ttgccttaat
    25081 caattccata tcaataccag tgtattggtt gcttgaattt tggaaaacaa aaggggcaaa
    25141 agaagaatcg ctggcaatga tatatttagc cttaacagga atagctttta atcctgcgag
    25201 agtagttgta gttggcactg ctgaagatga tgaagcagtc catttcttga taattttatc
    25261 aagactacca tcttttttca tttcagacaa ggcttggtta aattcagtaa ccaggtgctc
    25321 gtatttactt ccttttttca caccgaaagc aaaacttcct acagcttcac catccatttc
    25381 aatatggagg tcttgacctt ggttaatggc atattcgata acaggtttgt catccatcat
    25441 ggcatcgatg gcaccagcac tcaagctgtt gttcattaaa tcaccagtgt caaatgtttt
    25501 aatagtaaag ccgtatttat ctttgattgt ttcaaggaaa cgttgagcgg cagttccgtt
    25561 tttaacacca acggttttgc cagttaattg gtcgtacttg ctaattttgt gtgactttgt
    25621 agtagcaatg acaacttttg tatcatagta agtatcagac atggtgaaga ctttttcacg
    25681 ttctttagtc tttgtcatcc ctgccatgat agcgtcggct tgcccagctt gaaccgcatt
    25741 gactgctgcg tcaaatccag gataggacat ctgaatgttc cagcctttaa tctcagcgac
    25801 tttgttaata atgtcaacat caattccttt ataagtttga tctgaatctt taaactcaaa
    25861 aggtgcatag gcggtatcag aaacaatctt aatcgtttct gctttggcaa tacctaatga
    25921 gaaaattggg aataaaatta gcaaaaatgc tagaaatttt ttcttcattt ttagtctcct
    25981 tttccgaata ttctctcatt atatcagaaa aagtaaaaaa aggcaaattt ttatattttt
    26041 tgtgtcagaa aatataacat cgattttttc ctttccttga attgctatta aaaagtgcta
    26101 taataatagt atatatagaa gaaaagagga cggggatatg aagaacaaaa gaatatttaa
    26161 agacttccaa gcttcaaaaa tgagtttaaa catttacaca agccccttgt tagcctttgt
    26221 ttttgtcttc ataggagagt ttgtggcttt tactttgtat ggtattggct tgttagctct
    26281 catcggactt gctagaaatt ttggagaggc tggtcaaaat cttgcaagct acttgcagac
    26341 cttgcatcag agcttgacgg ataaaacaag tgactttcgt ttaattttag gattactggc
    26401 ctttggtttt attcttaaca ctgtgttcag atggacaaga aaagttgaga aaagacctat
    26461 tcgaaccttg ggattttata gagagaattt cctcagcaat cttctgaaag gatttagtct
    26521 aggcctggca ctttttcttc tgaccttgtt aggtttagtg gtcttaggtc aatatcgttt
    26581 ggaatccatt cacttgaatc cttattctct tgcctttgtc gtctttacta tcccattttg
    26641 gattttacag gggacagcag aagaagtggt ggcccgtgct tggctacttc ctcaattggc
    26701 ctcaagaacc aatctaaaac tagctattct tatatctagc ctgttcttta ccctgcttca
    26761 tatgggcaat tctggtctca cccctctatc tctagtaaat ctctttttat tcggagttgc
    26821 catggctctt taccttctca aaactgatac agtttggggt gttgcaggta ttcatggtgc
    26881 ttggaatttt gctcagggta atctctttgg gattttagtt agtggtcaac cgtcaggaac
    26941 gtctctgatg acctttttac cacaaggcaa tcaagattgg ctatcaggtg gttcttttgg
    27001 catagaaggt tccattatga caagtctggt attactactg ctgattgtct atcttgctaa
    27061 taaattaaag aaagaaaatg aaaggatgtg acttcggtcc gtccttttct tcgtgaaaat
    27121 actataagta tgctaaaata ggaatagcac atggagagag gattcttatg atcaatcaca
    27181 ttacagataa tcaatttaaa ctagtatcaa aatatcaacc atcaggagat caaccccaag
    27241 ctatcgagca gttggtggat aacattgagg ggggagaaaa agctcagatt ctgatggggg
    27301 cgactggaac agggaagacc tatactatga gtcaggtcat ttctaaagtc aataaaccaa
    27361 ctctggttat tgcccacaat aaaactctgg ctggtcagct ctatggggag tttaaggaat
    27421 ttttccctga aaatgcagtt gagtatttcg tatcctacta tgattattac cagccagagg
    27481 cctatgtccc ttctagcgat acctatattg agaaggatag ttctgtcaat gacgagattg
    27541 acaagcttcg ccactcagct acctcagccc ttttggagcg taatgatgtt attgtcgtgg
    27601 cctcagtctc ttgtatctat ggtttgggtt cgcccaagga atacgctgat agtgtcgtta
    27661 gtctccgtcc tggtctagag atttctcgtg ataaactctt gaatgacttg gtcgatattc
    27721 agtttgaacg taatgatatt gatttccaac gcggaagatt tcgcgttcgt ggggatgtgg
    27781 tagagatttt cccagcttcc cgagatgaac atgcctttcg agtagaattt tttggagacg
    27841 aaattgaccg tattcgtgaa gttgaggctc tgacaggtca ggtgttggga gaagtggatc
    27901 atttagcgat tttcccagcg acacactttg tgaccaatga cgaccacatg gaagttgcca
    27961 ttgcaaagat tcaggccgag ttggaagaac aattagctgt ctttgaaaag gaaggtaaac
    28021 tgcttgaagc ccagcgtttg aaacagcgga cagagtatga tatcgaaatg ttgcgtgaga
    28081 tgggctatac caatggggtt gaaaattatt ctcgccacat ggatggacgg agcgaaggag
    28141 agcctcctta tacgcttctc gacttcttcc cagatgattt cttgattatg attgacgaga
    28201 gtcatatgac catagggcaa atcaagggca tgtacaatgg agaccgttcg cgtaaagaaa
    28261 tgctggttaa ttatggtttc cgtttgccgt ctgctttgga caatcgtcct ctccgtcggg
    28321 aggagtttga gagtcacgtt catcagattg tttacgtttc agcgacacct ggtgactatg
    28381 aaaatgaaca gaccgagaca gtgattgagc aaatcattcg tccaacggga ctcttggatc
    28441 cagaggtgga agtccgtccg actatgggac agattgatga cctcttgggt gaaatcaatg
    28501 cccgcgttga aaaaaatgag cgtaccttta tcacaacttt gaccaagaaa atggcagagg
    28561 atttgaccga ctacttcaag gaaatgggta tcaaggtcaa gtacatgcac tcggatatca
    28621 agaccttgga acggacggag attatccgtg acctgcgctt gggtgtcttt gatgtcttgg
    28681 tcggaattaa cctgctccgt gaaggaattg acgttcctga agtgagcctc gtagctattc
    28741 tcgatgctga caaggaaggt ttccttcgca acgaacgtgg actcatccag accattggac
    28801 gtgctgcacg taatagcgaa ggtcatgtta tcatgtatgc ggacacggtt acccagtcta
    28861 tgcaacgtgc tatcgatgaa actgcccgcc gtcgcaaaat ccagatggcc tataatgaag
    28921 aacatggtat cgttccacaa accatcaaga aagaaatccg tgacttgatt gctgtgacca
    28981 aggcagttgc taaggaagaa gacaaggaag tcgatatcaa tagcctcaac aaacaagagc
    29041 gcaaagaact agtcaaaaag cttgagaaac aaatgcaaga agcagttgaa gtgcttgact
    29101 ttgaactagc agctcagatt cgtgatatga tgctggaagt caaggccttg gattagggga
    29161 atagtatgat ttatttaaga aagttaaaga aagaagattt gatgtcttta tgggaaatgg
    29221 cttattcaca gcttaatcca gtttggaaac agtatgatgc tccctattat gatgattatc
    29281 agtatttttc aaattttaaa gaattcgaac tacaaaaatc agaatccatt ttaagcaact
    29341 caaatcgcct tggtattttt gttgatgata aactagttgg gactgtttcg cgttattggg
    29401 tatgtaaaga aacaagatgg atggaattgg gaattggtat ttatgataaa aaattctgga
    29461 acactggtat tgggaaagtt gctatgttgc agtggataga taggacgttt caggattact
    29521 tggagttgga gcatctgggt ttgacaactt ggtcaggaaa tattggtatg atgaaacttg
    29581 ctgaaaaatt aagaatgaaa aaagaagctc atattccaaa agttcgttat tatcaaggta
    29641 aatattttga cagtattaaa tatggtattt tgagagaaga ctgggagaaa ataaatgacg
    29701 gttattatca aatcaatgga aactcctgaa gagatagaag gtaaatcctt cgttcactgg
    29761 caaacgtgga gagaggctta tgatgacctt ttgcctgcgg aatttcagga gacaatgaca
    29821 ttagaaagat gtcgactctt tagtcaaaag tatccagaaa atacattgat tgcgatggat
    29881 ggtgtgaaga tagttggttt tataagttat ggcaactgtc gtgatgagac tattcaagct
    29941 ggtgaaatta ttgctttata tgttttaaaa gactattatg gaaaaggaat cgcacaaaag
    30001 ttagtgaaag cagctttgac tgatcttaat catttttctg aaattttctt atgggtattg
    30061 aaagataaca agcgcgccat tgctttctat caaaaaatgg gttttacttt tgatggacaa
    30121 gaaaaaatac ttgaacttgg aaagcctata aaggaaaaac ggatggtatt ctattctaaa
    30181 taattctcaa aagtaaaagc taatatggta ccaagtctga aaatttaata aattagaaag
    30241 cgagtaaatt tatgtcccgt tcccaattaa caattttaac aaatatctgt ctgattgaag
    30301 acctcgaaac tcagcgcgtg gtgatgcagt atcgcgcccc tgaaaacaat cgctggtctg
    30361 gttatgcctt tcctggaggt catgtagaaa atgatgaggc ttttgcggag tctgtcattc
    30421 gtgaaatcta cgaagaaaca gggttgacta tccaaaatcc tcaacttgtc ggcattaaaa
    30481 attggccact agatacaggt gggcgctata ttgtcatttg ttataaggcg actgagttct
    30541 ctggtaccct tcaatcttca gaagagggag aagtttcttg ggtgcaaaaa gaccagattc
    30601 caaacttaaa tctggcctat gatatgctac cattgatgga aatgatggaa gctcccgaca
    30661 agtcagagtt tttctaccct cgccgtacag aagacgattg ggaaaagaaa atcttctagt
    30721 cttttactaa ataacctagc tgatccaagg cctcctcgat atagtggagg tcttgttgtg
    30781 tctcggcttc aactaggtga taatgaatac catctgttaa ctcagaaatt ggcttaaagt
    30841 cagaacgttc aacttgttct agaaaatgtt gcacgtcgcg gcgacaggtc agttttagta
    30901 aggtttcaat ctctccataa acaggatgat caatcaagat attttgaacg cgaccaccat
    30961 tatctacgat agcaagtaat tctcgtccaa tttcttcaac ttcatgcttg accttaaata
    31021 atttgtgatg ataagtattt gcattagcat ctttatagat ataaccacga ttggtagata
    31081 gaattggaga tccatcagct cttaaaattg caatatcttg aacaataact tgtcgagtga
    31141 catgaaagtg ctcagctaat ctttggccat tgagggcttt aggagcttct ttcaagagtt
    31201 ggagcagggc ttgtttgcga tcttttgtca tagttcttcc ttttaacggc gttttcgaag
    31261 cactttatag acagctagtg ctaatgtata gtctaccata ctatggataa ttgtaccaaa
    31321 tccaactagt acaaatagaa cataaaacat attttctaca ttggtaccag aagttgcgta
    31381 aaaaacgaca caggccaata cttcagcaag ggcatgaaca acagccaaaa caaagttgaa
    31441 aatccaggaa gattttggtt tatctagggt atcggggaat ttttgtaggt aaagagctcc
    31501 taaagcacca aaagatatat gggaaaaagc ccgaaaaacg ataaccatgg gatagccagc
    31561 catcaaaaat ccaaaactag aggctaggat gacaaaaact gccatcaagg gcgacaagaa
    31621 catggctata aaaatagcga tgtggctccc caaagtatag gaagcaggtg gaatgacaat
    31681 cttgaaaggc ataacaattg gaatcaaaat cgcaatagcc gttaaaaggg ctgtcattgt
    31741 cataaattgt gtctttttcc gtgtattcac aagaatctcc tttttaactg catatacact
    31801 agtatggtac aataaaccag acaataaagc aagaatttac ttgggtttat agatcatttt
    31861 ttagttaaaa gttatagtag attgaaacta gaatagtcca cctctacttc taaaacattg
    31921 ttagaaatcg atttggctgt cctgatcgat ttgtcctgtt cttatttcgt tttactatag
    31981 taaagatttc attaaaaaga aactgtatag agcaaaatct tcaccttcag gtttgaaagc
    32041 ggagattgtt tttatttttt caaggtttgt agtcgtggaa caatggctag ggttagaatt
    32101 gcagaaatga ccaattcagc aattgaattt gttgagataa cggttgccag aagaagttgg
    32161 atatttccat tataaacatt tccaaatagg aagaagattc ctccaaggac aaagatagta
    32221 tttgtcaagg aaccaagggc tccagctaaa atcagaccag tcttgttttt catcagttta
    32281 tagactaagt aaggagttaa accaatcaaa atacgtggga cgatggcaat gatagctgag
    32341 tagatgtttc cgtttggtac gaagggagag aagaggtagc ttgtcggtag aatcgtaatc
    32401 gtgttaaccg tcaagctaag taatcccatc aaaaatccaa gtgtaacccc aactcgtgga
    32461 ccataaataa tgctggcaat aatgacagga atatgaacaa tggtcggttt gattggaaat
    32521 ggaaaaaggt taaagataag tgagctcaga aagtgtatca cgagcatggt agcaaaaaag
    32581 atagcaatgg gtgcaatatt agagcgtttt ttcatcgata gtttccttta ttctttctaa
    32641 aataattgtg aggtcagcta aagctcctcg tccgtggtct ccacaagcta gtagggattc
    32701 cttaggagca atcagctgat agccgtaggt ttctaatgtt ttcagattat tctgagttac
    32761 tggatggtca tacatttttg tattcatagc aggagctatt agtttgggaa tatgacttgg
    32821 tagggctaga gctgtactgg ttaccatgtt gtccgcaaat ccgtgagcta gttttgcaat
    32881 agtgttagca gttgcaggta ccacgataaa taaatctgct ttttttccaa gttcgatatg
    32941 attgacctga tcaggatagg gttccttcat gacatccaag tggacaggat tctgtgagag
    33001 tacctgtagt gtcaaaggtt ggataaactc tgtagcagcc tgagtcatta agacagtgac
    33061 ttgatggcct tgttttttta gagaactgac taaatctgcc gacttataag aggcgattga
    33121 acccgttaca gccaagagaa tgtttgccat agttttcctt tctaagaatg ataggcttga
    33181 attttttcaa ggaggagttc tgcaatttct tctttagtct ggactgtttg aagctgattt
    33241 ttctcaacaa atatagctcg gtgctgatct gctgaaattt gagtcaggtc attcgcgatg
    33301 attaaatctg cttgattctt gataagactt tttcgtgcaa tgtcaaccag atgatcttcg
    33361 gtaacatcaa ccagcagttt gaaaccaatc agatgaatag taggattcca ttccttgact
    33421 agggatatga ttttgggtgt ctttttaagg aacaaaacct gaacctcatc agttgaagaa
    33481 atcttggcct gatgattttg cttgcttaaa aattctttta gattggagct agcctgaact
    33541 tcctcaagcc ctgtcatata aacaggagtg tagtcagaaa cagccattga gtggatcaag
    33601 acctgataat cctgaacacg ttcttgcatt tctattagaa ggtccttggt attggtaatt
    33661 tctcgaatac ttaggttagg atgaggctct ggcttcagag ctcgttttgt cgtaattaaa
    33721 caaacttcat accctgcaga aagcaaagtc tctgtgataa ttttccccaa gtgacctgta
    33781 gaatggttag tgatagagcg gacgctatcg atagcttcac tggtaccgcc cgatgtaact
    33841 aaaattttca tagcactatt gtacacaaaa ataagcggta agtaaaatga aagtgataaa
    33901 tttttggtaa aaacgaagat ttattatagt ttcaaactat aaagccatat aaaatttaag
    33961 aaaggactct aaaagtctta aaaacagaga tatttacgaa cgtttagaga gttttaggat
    34021 gttaaaaatc ttgttttgtg atataatgaa ttatcatata agaggttaga ggaattttga
    34081 atgaaaacag atattgaaat cgcacagagt attgagttga agccaattgt tgatgttgta
    34141 gagaaacttg gtatttctta tgacgatttg gagttgtacg gaaagtacaa ggctaaactc
    34201 agctttgata aaattcgtgc agttgagagc aatccagtcg gtaaattgat cttggttact
    34261 gccatcaacc caacacctgc aggtgaagga aagtcgacgc ttaccattgg tcttgcggat
    34321 gccttgaaca agattggcaa gaaaaccatg attgctatcc gcgaaccgtc tcttggtcca
    34381 gtcatgggga tcaagggtgg tgctgctggt ggtgggtatg cacaagttct gccaatggaa
    34441 gacatcaacc tccactttac tggagatatg catgctatta caactgccaa caatgccctt
    34501 tctgccttga ttgacaacca cttgcaccaa gggaatgagc tgggaattga tcaacgtcgt
    34561 atcctctgga aacgcgttgt ggacttgaac gaccgtacgc tccgccatgt gactgttggt
    34621 cttggtggtc ctctaaacgg tattccacgt gaggatggtt ttgatattac agttgcttca
    34681 gaaatcatgg caattctttg cttggcaacg gacatcgagg acttgaaacg tcgtttggcg
    34741 aatatcgtta ttggttatcg ctatgaccgt acgcctgttt ctgtaggtga tttgcaggtt
    34801 gagggtgcct tggctttgat tttgaaggat gctattaagc caaacttggt tcagacaatt
    34861 tacggtacac ctgcctttgt acacggtggt ccatttgcca atatcgctca tggctgtaac
    34921 tctgttttgg cgacgacaac agcccttcac ttggctgatt acactgttac tgaagctggt
    34981 tttggtgcgg accttggtgc tgagaaattc cttgatatca agacaccaaa cttgccaaca
    35041 tctccagatg cagttgttat tgtcgcaacc cttcgtgccc ttaagatgaa tggtggtgtg
    35101 gctaaagacg ctctgactga agaaaatgta gaggcagttc gtgcaggttt tgctaacttg
    35161 aaacgccacg ttgaaaatat ccgtaagttc ggtattccag cagttgtagc tattaacgaa
    35221 tttgtatctg atacagaagc tgaaattgca gccttaaaag aactctgtgc ctcaatcgat
    35281 gtaccagttg aattggctag tgtctgggct gatggagcag aaggtggagt agcacttgcc
    35341 gaaacagttg ttaagacaat tgctgaaaat ccagctaact ataaacgttt gtatgataat
    35401 gacctttctg tccaagaaaa gattgaaaaa attgtcactg aaatctatcg tggtagcaaa
    35461 gtgaactttg agaagaaagc tcaaacacaa attgctcaaa tcgttcaaaa cggttgggac
    35521 aaattgccaa tctgtatggc taaaactcaa tacagtttct cagacaatcc aaatgcgctt
    35581 ggagcaccag aaaactttga aattaccatt cgtgaattgg taccaaaatt aggtgcaggc
    35641 ttcatcgttg ccttaactgg tgatgttatg accatgccag gtcttccaaa acgtccagca
    35701 gctctcaaca tggatgttga aagcgatgga actgtactag gcttgttcta gtggattgaa
    35761 attgacttta agtgagtttg gaaataatat ccaagctcat tttttctcag actgcaagca
    35821 gttcatcaat aagatttata ctcttcgaaa atctcttcaa actacgtcag cttcaccttg
    35881 ccgtaggtat atgatactga ctctgtcagt tctatccaca acctcaaaac agtgttttga
    35941 gcaacctgcg gctagcttcc tagtttgctc tttgattttc attgagtata agtagataga
    36001 aaagttatat actatctatt gaaaatatta taaatcagat acaaagacag gtgaaacctt
    36061 ctgtgttata ctagagatat gttagatttg aaagaatacg gtatcgtcat gtggccggag
    36121 gagaaagtca tttctttccg tgagaaactt ctcgcttggt atgatgaaaa caaaagagat
    36181 ttgccttgga ggagaagtaa aaatccttat cacatctggg tatctgaaat catgcttcag
    36241 cagaccaggg tggatacagt tatcccttac tacgaaagat ttttggactg gtttccaact
    36301 gtcgaaagtc tggcaactgc gcctgaggag agtttactga aagcttggga gggcttgggc
    36361 tattattctc gagttcgcaa tatgcaggct gcagcccagc agattatgac tgactttggt
    36421 ggccaatttc caaataccta tgaaggaatt tccagcttga aagggattgg accttacaca
    36481 gcaggagcca tttccagtat tgcttttaac ttgcctgagc cagctgtaga tggtaatgtc
    36541 atgcgggtct tggcgcgtct gtttgaagtc aaccacgata ttgggattcc aagtaatcga
    36601 aaaatttttc aggcaatgat ggagatcttg attaatccgg atcgtccggg tgattttaat
    36661 caagccttga tggacttagg gtctgatatt gagtctcctg taaatcccag acctgaagaa
    36721 agcccagtca aggactttag tgcggcatat cagaatggaa ccatggaccg ttatccaatt
    36781 aaatctccta agaaaaagcc ggttcctatt tatcttaaag ccttagttgt gaaaaattct
    36841 caaggacaat ttttacttga aaaaaatgaa agcgaaaagc tcttggcagg tttttggcat
    36901 ttccccttta tagaagttga taacttttcg caagaagagc agtttgacct ctttcatcag
    36961 gttgcggaag aaagtgtgaa ctttggtccc agtccagaag agagtttcca gcaggactat
    37021 gacctagatg ttgattggct tgatgtttgt tttgatacag tccagcatgt ttttagtcat
    37081 cgaaaatggc atgtacagat tgtagcaggt caggtgagtg acttccatga tttttcagat
    37141 agggaagttc gctggctttc accagaagaa ttcaagaatt acccacttgc caaaccccaa
    37201 caaaaaatct ggcaggttta tgcacaagcc aacttagaca gtagccaaga ctagctattg
    37261 tgtcttctga ctattttttt ggtataatag tagagaaaaa ggtgaacata tgaaaaaaat
    37321 actaattgta gatgatgaga aaccaatctc ggatattatc aagtttaata tgaccaagga
    37381 aggttacgaa gttgtaactg cttttaatgg tcgtgaagcg ctagagcaat ttgaagcaga
    37441 gcaaccagat attattattc tggatttgat gcttccagaa attgatggtt tagaagttgc
    37501 taagaccatt cgtaagacaa gcagtgtgcc cattcttatg ctttcagcca aagatagtga
    37561 atttgataag gttatcggtt tggaacttgg ggcagatgac tatgtaacaa aacccttctc
    37621 caatcgtgag ttgcaggcgc gtgttaaagc tcttctgcgt cgttctcaac ctatgccagt
    37681 agatggtcag gaagcagata gtaaacctca acctatccaa attggggatt tagaaattgt
    37741 tccagacgcc tacgtggcta aaaaatatgg cgaagaacta gacttaaccc atcgtgaatt
    37801 tgagcttttg tatcatttag catcgcatac aggtcaagtc atcacgcgcg aacacttgct
    37861 tgagactgtc tggggttatg actattttgg tgatgtccgt acagttgatg tgactgtacg
    37921 acgtctgcgt gagaagattg aagatacgcc cagccgacca gagtatatct tgacgcgccg
    37981 tggtgtaggg tattacatga gaaataatgc ttgatttact gaaacaaacc atttttacca
    38041 gagattttat ctttatcctg attttgttag gtttcatcct tgttgtgacc ctcttattac
    38101 tggaaaatag acgtgataat attcagttga agcaagtcaa tcaaaaggtt aaagatttga
    38161 ttgcaggaga ttattccaag gttcttgata tgcaaggtgg gtctgaaatc accaatatta
    38221 ccaataattt gaatgacttg tcggaggtta ttcgtctcac tcaggaaaat ctagaacaag
    38281 agagtaagag gctaaatagt attctgtttt atatgacaga tggggttctt gcgactaacc
    38341 gtcggggtca gattatcatg attaacgata cagccaagaa gcaactgggg ttggttaagg
    38401 aagatgttct gaatagaagc attttggaat tgctcaagat agaagaaaac tatgaattgc
    38461 gtgatttgat tacccaaagt ccagaattgt tgctagattc ccaagatatc aatggcgaat
    38521 atttgaacct tcgagttcgc tttgccttga tacgtcgaga gtctggcttt atttcaggtt
    38581 tggtggctgt tttgcatgat acgacggagc aggagaagga agaacgcgaa cgaagactct
    38641 ttgtttccaa tgttagccat gagttacgga ctcctctgac tagcgtaaaa tcctatcttg
    38701 aagccttgga tgagggggct ttgtgtgaaa ctgtagcacc agactttatc aaggtttctc
    38761 ttgatgagac caaccgtatg atgcgcatgg tgacggatct cctccatctt tcacgtattg
    38821 ataatgctac cagtcaccta gatgtggaac tgattaactt cactgctttt attaccttta
    38881 tcctcaatcg ttttgacaag atgaaaggac aggaaaagga gaaaaaatat gagttggtga
    38941 gagattatcc catcaattct atctggatgg aaattgatac agataagatg acgcaggttg
    39001 tcgacaatat tttaaataat gctattaagt attcgccaga tgggggtaaa atcactgtca
    39061 gaatgaagac aactgaagac cagatgattt tatccatttc tgaccacggt ttggggattc
    39121 ctaagcagga tttaccacgt atctttgacc gtttctatcg tgtggatcgt gctagaagtc
    39181 gtgcacaagg tggtacaggt ctaggactgt ctatcgctaa agaaattatc aaacaacata
    39241 agggctttat ttgggccaag agtgaatacg gcaagggttc aacctttacc attgtactcc
    39301 cttatgataa ggatgcagtg aaagaagaag tatgggagga tgaagtagaa gactagaatg
    39361 agtgaaatag gctttaaata cagtatttta gcgtcgggtt ccagtggaaa ttctttttat
    39421 ctggaaacct caaaaaagaa gcttttagta gatgcaggct tgtctggcaa gaaaattacc
    39481 agtctgctag ctgaaattaa ccgtaagcca gaagacctgg atgccatctt gattacccat
    39541 gagcattcag atcatatcca tggagtaggc gttttggctc gcaagtatgg tatggatctt
    39601 tatgccaatg aaaagacctg gcaagctatg gaaaatagta aatatcttgg caaggtggat
    39661 tcttcgcaaa agcatatttt tgaaatgggt aaaaccaaaa cctttggaga tatcgacatc
    39721 gagagttttg gtgtaagcca tgatgcagtc gcaccgcagt tctatcgctt tatgaaggat
    39781 gataagagtt ttgtcctctt gacagataca ggttatgtca gtgaccgtat ggcgggcatt
    39841 gtcgaaaatg cggatggtta tcttatcgag gccaaccatg atgtagagat tttgcgatca
    39901 ggttcttacg cttggcgact caaacaacga atcctatctg accttggtca cctttctaac
    39961 gaggacggtg ctgaagctat gattcggacg ctaggaaatc gtactaagaa gatttacctt
    40021 gggcatttat ctaaggaaaa caatatcaag gaactggctc atatgaccat ggtcaatcag
    40081 ctggctcaag ctgatctggg agtcggagta gactttaagg tttatgatac ctcaccagat
    40141 accgcaacac cattgacaga gatatagaaa gaacgctgag aaggtgttct ttttatattg
    40201 actgaacacc taaaaagtaa tacaatggtg ttaccattaa aaaagggagc acaaaagatg
    40261 actactatta cattaaaagt ttctgaagct gataaaacat ttatgaaagc aatggctaag
    40321 tttgaaggag tttccctttc ggaacttatt cgcaccaaaa ctcttgaagc cctagaagat
    40381 gaatacgatg ctcgtgtggc agatttagcc tatcaagagt atttagaaga cttggaaaaa
    40441 ggagttgaac ccattacttg ggaagaaatg atgcatgatt taggcttgaa ggatgaataa
    40501 tttgtataaa ttagttccaa caagacgttt tatcaagcaa ttgaaaaaat tggaccgtta
    40561 tacgcagaag ctaattacaa actatttaca aaccaatgtt ttggaagacc caagacgaca
    40621 cggaaaggct ttggttggta atcgcgttgg tcaatggcgc tatagaattg gtaattatcg
    40681 agttatcgta caaattgtag atgatgaatt agtcgttgct actctagaag ttggtcatcg
    40741 gagagatatt tattgaatta cttttttcaa gtaaattttc attctttaaa atatgatata
    40801 atagggctta caatataaga gaggttgctg atgacaatag atattagtga agaaagtttg
    40861 gctaaagaat cggctgactt attaaaaatt cttttaaaag atcgaacgac aaagaaatca
    40921 attgtttggg ctacgcattc ttatgaattg ttaggaaagg gatttgctcc aagtgatcgc
    40981 atcaatccaa gtaaggttac tggaaacttt gccaacttga ttcagcccag atctgaaaaa
    41041 tccaaatatg aacaaaaaga tcggacaaaa ataagggcag aagtgtttac accaacgtgg
    41101 ttggtcgcaa agcaaaatgg atatgtagaa tcgaaattag gctcgttaag tcttgaggag
    41161 tatgtggact tacgatggtt agaggtaact tgtggtgaag caccttatat ggtaacgaga
    41221 tatgataccg taactggtga ggaaattcca ttatctgagc gagttggttt tgttgataga
    41281 aaactgcaac ggattagtcg tgaggtttca gatgaagtca cattttataa acttgtaaaa
    41341 gatgcttatc atgcttcgta tggttatgag tatcaaggag attctctcct tttggcgcgt
    41401 gagaatcttt tggcaacttt tgaggactat tatctagcta agactggaaa tcaaccaaca
    41461 ttagagcaaa agaaagaaat tgcgactatt atctcttaca atgtctttca gatggatgga
    41521 ttgaaaaaaa gtagtcctta ttcagctaaa caaaagcaat ctcaacaatt gagtttgttt
    41581 gcggatgagc tagaagtcca agaagtagaa gaatctaaaa cccatatcaa agactggaaa
    41641 aagaatagaa tgataggttt tgagcgccta tctagcgagg aaagtgaaat gaaatttgat
    41701 gtcgtgatag gaaatcctcc gtatcaggaa acaggagaag ccagagatga gccgatatat
    41761 cactatttta ttgatgaagc ttataaaatc gcagataaat ctatactaat caccccagca
    41821 aggtttttat ttaaagctgg tcaaactcct aaaaattgga tggaaaagat gcttgaagac
    41881 aagcatttaa aagttcaatt ctatgaactt aaaagcggta aagtatttac aggaacggat
    41941 attaagggtg gagtagcaat aacttatcgt gatgttgata aagatttggg accaatcgga
    42001 gtatttacta tttttgaaac tttgaatggt attgtaaaaa aaatcgaaaa acatccagaa
    42061 tttgaaactt tttctgattt agtttatcct caaggtattt atagattttc aaataaactt
    42121 ttttctgatt atccaaatgc tgaaaagctg caaggaaaag ggacaaaaaa taaaattgtt
    42181 tcgaaatcac taactcagtt agattttgtt ttcaaaaaca acgaagaaaa agaccatgtt
    42241 gctctacttg gaagaattgg ctccgaacgt gtttatcgat atattaataa aaaatattta
    42301 gatttaccgg aaacattcga aaattataat gtttttgtac cagaagctaa tggaagtggt
    42361 gccttaggtg aagtcttatc aacaccccta atcggggaac ccctaatcgg gcatacagat
    42421 acttttttat ctattggtaa ttttaaaaca aaatttgaag ccgatgcttg tattaaattt
    42481 attaaaacta aattcgctag agtattatta ggtgttttga aagttactca gcataattca
    42541 cgcaaaactt ggtattacgt ccccctccaa gactttacgg tcaattcgga cattgattgg
    42601 acacaatcag tgactgatat tgaccgccag cttgatcaaa aatatgacct ttcccctgaa
    42661 gaaattgcct ttattgagaa tcatgtaagg gagatggatt agaaaagtat ttttatttga
    42721 caaatagtgc tcaatgatct aaaatgacta tataggatta ggtcaggaag catacgatgc
    42781 cctgaccctt tttgtactta tgagatgaga aagtcatttg ttagataaat tgacttcgtt
    42841 agcaaacgtt caaaaaagga aaacttatgc cagtagaaat taaaaccact aaagaaattc
    42901 atcctaaaat ctatgcctac accacaccga cagtaaccag taatgaaggc tggattaaga
    42961 ttgggtatac agaacgtgat gtcacacaac gtatcaagga gcaaacgcat acagctcata
    43021 tagctacaga tgtcttatgg actggtgatg cagcttatac agaagagcct gataagggga
    43081 aaactttcaa ggaccatgat ttccaccatt tcctttcttt ccatgatgta gaacgtcgtc
    43141 ccaagacgga atggttctat tttaatggaa ctcctgaaaa atcaaaaaat ctttttgata
    43201 agtttgttca gcatgatttg tctggttatc agcctggaaa aggacaggac tatactctgc
    43261 gacaagagca agaagaagca gttgctaaga cattagctta tttccaagaa catgctggag
    43321 gcaagtttct ctggaatgcc aagccacgct ttggtaaaac cttgtctacc tatgacctag
    43381 ctcgacggat ggaagctgtc aatgtcctaa ttgtaacaaa ccgccctgcc attgctaact
    43441 catggtatga tgattttgaa acattcatag caggtcaaac gacttacaag tttgtttctg
    43501 aatcagatag ccttaagagt cgtccaatct tgtcacgaca agaatttctt ggtattttag
    43561 ctgacgatgt aagacaactt gcttttatca gtctccaaga cttgaaagga tctgtttatt
    43621 taggtggaga gcacgataaa ctcaaatggg taactgatct gcattgggac ttgttggtta
    43681 ttgacgaggc tcatgaagga gttgatacct tcaagactga ccaagccttt aataagattc
    43741 gacgaaattt tactctgcat ttgtcaggta catcatttaa agcattggct aaaggagatt
    43801 ttacagagga acaaatctac aactggtctt atgctgatga gcaggctgct aagtattcgt
    43861 ggtctcttga gcaagaagag gaaaatcctt atgaaagctt gcctcagttg aatctcttta
    43921 cctatcaaat gtctcagatg attggcgaaa agttagaaaa aggcgctcag atcgatggtg
    43981 aaaatattga ctatgttttt gacttaagtg aatttttcgc tacagatgat aaagggaaat
    44041 ttattcatga gcatgatgtc agaaattggt tagatactct atcaagcaat gaaaaatatc
    44101 cattttcaac caaagaactc cgtaatgaac tcaagcatac tttttggctt ttagaacgtg
    44161 tcgcttcggc caaagcatta aaagccctac tagaagaaca cccaatctat gaaaactatg
    44221 agatcgttct agctgctggt gacggacgta tgtccgaaga agacgataaa gtcaaactca
    44281 aatccttgga cttggttaga aaagcgatag cagagaatga caaaaccatt accctatccg
    44341 ttggtcagct gacgacaggt gtcactatcc ctgaatggac aggtgtattg atgttatcaa
    44401 atttgaaatc accagctctt tatatgcagg ccgccttccg tgctcaaaat ccttactcat
    44461 ggagcgataa caaaggaaat cactttcgca aagaaagagc ctatgtattt gactttgcgc
    44521 cggaaagaac cttgattctc tttgatgagt ttgccaacaa cttattgctt gtaactgcag
    44581 ctggtagagg aacttcagct acacgcgaag aaaatattag agaattatta aacttctttc
    44641 caattattgc cgaagaccgt gctggtaaga tggttgaaat tgatgcaaag gcagttctaa
    44701 ccactcctcg ccagataaaa gctagagaag ttcttaaacg aggttttatg tccaatctct
    44761 tatttgataa tattagtggt attttccaag caagtcaaac agttttagat attttaaatg
    44821 agctgccagt tgaaaaggaa gggaaggtac aagatagttc tgatttatta gatttttcag
    44881 atgttacagt cgatgatgag ggaaatgcag tagtagacca tgaaattgta gttaatcagc
    44941 aaatgcgact ttttggtgaa aaagtttatg gacttggtga atctgttgct gagttagtca
    45001 caaaagatga ggaacgaact caaaaacagc tggtcaatga cttgagtaag accgtttctt
    45061 cagtgattgt agaggaattg aaagcagatt attctctaaa aacaagggaa actgagcaaa
    45121 ttaagaaaca aattacagca acacttgaga atgaaattcg aaaaaatgat atcgaaagaa
    45181 aaatttctga agctcatatc aagcaagagt tgcaacagca gctcaaagaa gcaaatgata
    45241 aagcgcaaaa agataagatt caagaagatt tggaaaaacg tttagaagaa aataaactca
    45301 ttcataaaga aaaactagaa caaacactca aaaaagaagt ggaaaaaatg cctgagaaat
    45361 ttatcgaaca ggttgagata aaacgtgtgg aacagttgaa acaatcagct caagatgaaa
    45421 ttcgtgacca tttacgaggg tttgcaagaa caattccaag ttttattatg gcttacggtg
    45481 atcaaactct aacacttgat aattttgatg cctttgttcc tgaacatgtt ttttatgaag
    45541 taacagggat tacgattgat cagtttagat atttgcgaga tggtgggcag gattttgcag
    45601 ggcatctctt tgataaagca acatttgacg aagctattca agaatttctt cgcaagaaaa
    45661 aggagttggc ggattatttt aaagatcaaa aagaagacat ttttgactat attccaccgc
    45721 agaagaccaa ccaaattttc actcctaaac gagtggtgaa aaggatggta gatgatttgg
    45781 aaaaggaaaa tccagggatt tttgatgatc catctaagac ttttattgat ttatatatga
    45841 agtcaggcct ctatattgca gaacttgtga agcggttata taatagcaat ggcttgaaag
    45901 aggcctttcc aaatcctgaa gaacgcttaa aacatatttt ggaaaagcaa gtttatggat
    45961 ttgctccgtc tgagattatc tataacattt ccactaattt tatatttggc aatctttcta
    46021 aagatatcag taggaagaat tttgttttag cagataccat tccagcggct aaagaaggga
    46081 gcattcaaaa gttggttgat tcctattttg aaaataatta aaaagaaggc cgagtcaaaa
    46141 ttctttgaaa tcagaaaaaa cgcataatat tgagtgcttt tgtactgccc cccaaaagtt
    46201 agacagaaaa aatctaactt ttggggggca gttcagacaa tccttggtat tatgcgtttt
    46261 attgtgggaa gatgtataat ggattgaaat aagatatgaa caaatcaatt aggaatttaa
    46321 agcattttat aacaacgttt tagagtaatg gggggctatt tcaacttcaa cctactataa
    46381 tacagaaaaa aacaactccc tgataattca aggagttgtc tatagttaaa ttagttttta
    46441 gaagcttctt ggaattctgg gtttttccat gcttcgtcaa tgatagcttg taattcttta
    46501 gcagatgctt gcattttttg agtttctgcg tcgttcaatg ggatatttac tggacgaacg
    46561 ataccatgtg caccaacaac agctggttga ccgataaaga cattctcaac tccgtattga
    46621 ccttcttgga atactgaaag tggaagtact gcgttttcat cgtcaaggat tgctttagtg
    46681 atacgagcaa gggctactgc gataccgtag tatgttgcac cttttttgtt gatgattgtg
    46741 taggctgcat cacgaacacc ttcgaacaat tcaatcaatt cagcttcttg aacattttga
    46801 gtgtctttaa ggaattcttc aaggtttaca ccagcgatgt tagcgtgtga ccaaacagcg
    46861 aactcagagt caccgtgttc acccatgatg taggcgtgca ctgaacgagc atccacatcc
    46921 aatttttcag caagtgcttg acggaaacga gctgagtcaa gtgaagtacc tgaaccgata
    46981 acgcgttctt tagggaaacc agagaatttc caagttgagt aagtcaaaac gtcaactggg
    47041 ttagcagcaa caaggaagat acctttgaaa ccagattcaa caacttgagt tacgattgat
    47101 ttgttgatag caaggttttt acctacaagg tcaagacgag tttcacctgg tttttgaggt
    47161 gcacctgcag tgatcacaac aaggtcagcg tctgcacagt cagagtattg agctgcatag
    47221 atttttttag gtgaagtgaa ggcaagggcg tgactaaggt caagcgcatc accaacagct
    47281 ttttcatgca attgtggaat ttcgataatt ccaagctctt gtgcaattcc ttggttaaca
    47341 agtgcaaaag cgtaagatga acctacagca ccatcaccga caaggataac ttttttgtgt
    47401 tgtttagttg aagtcattgt tttaaacatc tccttaattt tattagggga ttttccctag
    47461 acaacttcat tctatcactt ttaaaaaact ttgtcacgaa tatgccttat agttctcgat
    47521 gtaaacgttt tagtggttta gaggctgaaa tagatgggaa tttatggtat aatgttgtta
    47581 cttactaatt gtgaaatgag gcatttatta atgcaggata aaaatttagt gaatgtcaat
    47641 ctgacaaagg agatgaaggc aagttttatc gactacgcca tgagtgttat cgtagcgcga
    47701 gctcttcctg atgttcgaga tggcttaaaa cctgttcacc gtcgcattct ctacggaatg
    47761 aatgaattgg gtgtgacccc agacaaaccc cataaaaaat ctgctcgtat tacaggggat
    47821 gtcatgggta aatatcaccc acacggggat tcctctattt atgaagccat ggtccgtatg
    47881 gctcaatggt ggagctaccg ttacatgctt gtagatggtc atgggaattt tggttccatg
    47941 gatggagata gtgctgccgc tcaacgttat accgaggcac gtatgagcaa gattgctctg
    48001 gaaatgcttc gtgatatcaa caaaaataca gttgatttcg ttgataacta tgatgccaat
    48061 gaacgggaac ccttggtctt gccagcgcgt tttccaaacc ttttggttaa tggagcaact
    48121 ggtatcgcgg ttgggatggc aaccaatatt ccacctcata atctgggtga aaccattgat
    48181 gcagtgaagt tggtcatgga taatcctgaa gtgactacca aggacttgat ggaagtcttg
    48241 cctggaccag attttccaac tggtgctctt gtcatgggga aatcaggtat ccataaggct
    48301 tatgaaacag gtaaaggttc gattgtccta cgttctcgta cagagattga aacgactaag
    48361 actggtcgtg agcgtatcgt tgtaacagaa tttccttaca tggtcaataa aaccaaggtg
    48421 catgagcata ttgttcgctt ggttcaggaa aaacgcattg agggtatcac agcagtacgt
    48481 gatgagtcaa accgtgaagg tgttcgattt gttattgaag tcaagcgcga cgcctcagcc
    48541 aatgttattc tcaataacct cttcaaaatg acccaaatgc aaaccaattt tggtttcaat
    48601 atgctcgcta tccaaaatgg tataccgaaa attttgtctc ttcgtcagat tttggatgct
    48661 tatatcgagc accaaaaaga agtggttgtt cgtcgtacac gttttgataa ggaaaaagcg
    48721 gaagcgcgcg ctcatatctt agaaggtctc ttgattgcgc tagaccatat cgacgaagtg
    48781 attcgtatca tccgtgctag tgaaacggat gcggaagctc aagctgagtt gatgagcaag
    48841 tttaagcttt ctgaacgtca aagtcaagct atccttgata tgcgtcttcg tcgtttgaca
    48901 ggtttggaac gcgataagat tcaatctgag tatgatgacc tcttggctct gattgcggat
    48961 ttagcagata ttcttgctaa gcctgaacgt gtttctcaaa ttatcaaaga cgaattggat
    49021 gaagttaaac gtaaattttc tgataagcgc cgtacagagt tgatgattgg acaggtcttg
    49081 agtctcgagg atgaggactt gattgaagaa tcggatgtct tgattaccct ttctaacaga
    49141 ggctacatta agcgtttgga tcaggacgag ttcactgctc aaaaacgtgg gggtcgtggt
    49201 gtccaaggaa cgggagtgaa agatgatgac tttgttcgtg agttagtgtc aactagcacc
    49261 catgatcatc tgctcttctt cacaaacaag ggacgtgtct atcgtcttaa aggttatgaa
    49321 attcctgagt atggtcggac tgccaaaggg ctaccagtag tcaatctctt gaaattggat
    49381 gaagacgaaa gtattcagac ggttatcaat gttgagtctg atcgcagtga tgatgcttat
    49441 ctcttcttta caacccgtca cggtattgtg aagagaacca gtgttaagga gtttgccaat
    49501 attcgtcaaa atggtctcaa agcgctgaat ttaaaggatg aagatgagtt aatcaatgtc
    49561 ttgttggcag aaggagatat ggatattatc attggtacca agtttggtta tgcagttcgc
    49621 tttaatcaat cagccgttcg tggtatgagc cgtatcgcca ctggtgtgaa aggtgttaac
    49681 cttcgtgaag gagacacagt tgttggtgcc agcttgatta ctgatcaaga tgaggttctt
    49741 attatcacag aaaaaggata tggtaagcgt acagtcgcta ctgaataccc aacaaaaggt
    49801 cgtggtggta agggaatgca gacagctaaa attaccgaaa aaaatggctt gctggccggt
    49861 cttatgactg ttcaagggga tgaggatttg atgattatca ctgatacagg tgtcatgatt
    49921 cgaaccaatc ttgccaatat ttcacaaaca ggacgtgcaa ctatgggagt taaagtaatg
    49981 cgcctggatc aagatgctca gatagtgact ttcacaacgg ttgcggtggc agaaaaagaa
    50041 gaagttggga cagaaaacga aacagaaggt gaagcataat gtctcaaaaa aataataaaa
    50101 agaaaaacaa gcgaaaaaat ctgctgacaa atatcctagc aggatttctg atattactgt
    50161 cactggcttt gatttttaat actcaaattc gaaatatttt catagtctgg aataccaata
    50221 agtatcaagt tagccaggta tcaaaagaaa aattagaaga aaatcaggat acagaaggca
    50281 attttgactt tgattctgtc aaagctatct cttcggaagc tgttctaact tctcaatggg
    50341 atgctcaaaa attaccagtt attgggggaa ttgcaattcc tgaattggaa atgaatttgc
    50401 cgatttttaa aggacttgat aatgttaatc tcttctacgg agctggtaca atgaaacgcg
    50461 agcaagtaat gggagaagga aattatagtc tagctagtca ccatatcttt ggtgttgata
    50521 atgctaataa aatgttattt tctcctttag ataatgctaa aaatggcatg aagatttatc
    50581 taaccgataa aaataaagtt tatacttatg aaatacgtga agtcaaacgt gtgacaccgg
    50641 atcgtgttga tgaagttgat gatagagatg gggtcaatga aatcacatta gtaacctgtg
    50701 aagaccttgc tgctacagaa cgtattattg tcaaaggtga tttgaaagaa acaaaagatt
    50761 attcacaaac atctaatgaa atcctaacag ctttcaatca accatataaa caattttatt
    50821 aatacaaatc agtgaaatcc atgatttcac tgatttttta agattttcat aaaaatatag
    50881 taaaatgaaa taagaatagg acaaatcgat caggacagtc aaatcgattt ctaacaatgt
    50941 tttagaagta gaggtgtact attctagttt caatctacta taaactttta tgaaatacag
    51001 aaaacgcttc ctaaaaccta aagtttgtga tataattatc aagaaaaaag atttaggagt
    51061 ttattatggt ttcttcggaa tttatctcaa agattgaatt tgcttgcaat aagaaagaaa
    51121 gtctttatag tcaaagcaaa tttaagtatg cgattcgttc gatgttcgca ggtgcatttt
    51181 taaccttcag tactgctgca ggtgcagttg gggctgactt gattaataaa attgcaccag
    51241 gtagtggacg cttcctcttt ccattcgttt ttgcttgggg cttggcctac attgtttttt
    51301 tgaatgccga gttggtcact tcaaacatga tgttcttgac tgctggtagt ttcttaaaaa
    51361 aaatctcttg gagaaaaaca gctgagattt tactatactg taccttgttc aaccttatcg
    51421 gagccttgat agcagggtgg ggctttgctc attcggcagc ctatgcgaat ctgacacacg
    51481 atagtttcat ctcaggtgtt gttgagatga agttaggccg ctcaaatgaa ttggtcttgc
    51541 ttgaggcgat tttggcaaat atttttgtaa atattgcgat tctgtcattt attttggtca
    51601 aagatggtgg tgccaaactt tggcttgtgt tgtcagctat ttacatgttt gtattcttaa
    51661 caaacgagca cattgcggcg aactttgctt ctttcgcgat tgtgaaattc agtgttgctg
    51721 cggattcaat tgccaacttc ggtgttggaa atatgcttcg ccactggggt gtgactttca
    51781 tcggaaactt tatcggagga ggcctcttga tgggtcttcc atatgccttc ctcaataaaa
    51841 acgaagatac ttatgtagat taagaaaatg agcacgattg agtcgtgctt ttttcatttt
    51901 caaaataagg taatagctat ttcttatatc aaaatataga aaactgatat ttgtaaacta
    51961 taactcaagg tgctacaata tccttaataa aataatatgg aggtcacctt atgacttgtg
    52021 attttaaatt tgaaactcta caactacatg ctggtcaagt tgtggctcca gctactaagt
    52081 ctcgtgcagt gccgatttat caaacaacat tttttgtttt tgatgacacg taggaaggtg
    52141 ccgatctgtt tgccttgagg aaaccaggga acatttatac tcgtatcacc aatcctacaa
    52201 cagctgccct tgaaggtggt gttgaagcgc tagcaacagc atcaggtatg actgcagtga
    52261 cttatacgat tttggcgatt gcccatgctg gtgaccatgt agtggctgct tcgactattt
    52321 acggtggaac cttcaatctt ttgaaagaac cccttcctcg ttatggtatc acaacaacct
    52381 ttttcgatat tgataatttg gaggaagtag aagcagctat caaagacaat accaagcttg
    52441 tcttgattga aaccttgggt aaccccttga ttaatattcc agacctggaa aaactggcag
    52501 agattgctca taaacatcaa atcccacttg tgtcagacaa tacttttgca acaccttatt
    52561 tgattaacgt cttctctcat ggcgttgaca ttgccattca ctctgtgact aagtttatcg
    52621 gtgggcatgg tacaactatt ggaggaataa ttgtcgatag tggtcgtttt gactggacgg
    52681 cttcagggaa attccctcaa tttgttgacg agggtccaag ctgccacaat ttgagctata
    52741 ctcgtgatgt gggtgcagca gcctttatta tagctgttcg agttcaattg cttcgtgata
    52801 caggtgcagc cttgtcacca ttcaatgctt tcctcttgct acaaagactt gaaacctctt
    52861 cacttcgtgt ggaacgccat gtacaaaatg ctgagacaat tgttgatttt cttgtcaacc
    52921 atcctaaggt agaaaaggta aattatccaa aacttgcaga tagtccttat catgccttgg
    52981 ctgagaaata cttgccaaaa ggtgtcggtt caatctttac cttccacgtc aaaggtggcg
    53041 aggaagaagc acgcaaggtc attgataatt tagaaatctt ttctgacctt gcaaacgcgg
    53101 cagatgctaa atcgcttgtt gtccatccag caacaaccac tcacggtcaa ttgtcagaaa
    53161 aagacctaga agcagcaggt gtcacaccaa actaaattcg tttgtcaatc ggtcttgaaa
    53221 atgtagaaga tttgattgaa gacttgcgct tggccttgga aaaaatttaa agtaaaagaa
    53281 gataaacagt gggcttcgac tcactgtttt tgattttccc tcaggcatga tataatggtt
    53341 acagaagtct agaaagagga acgatatgaa cgaaatcaaa tgtcccaact gtggggaagt
    53401 ctttacagta aatgagagtc agtatgccga actcttgtcc caagtgagaa cggcagagtt
    53461 tgataaggaa ctacacgata ggatgaagca ggaactggcc ttgactgagc aaaaggccat
    53521 gaatgagcaa cagactaaac tggctcagaa ggatcaagaa attgcgcaat tacagagtca
    53581 gatccaaaac tttgatacag aaaaagaatt ggccaagaaa gaggttgaac agacaagcca
    53641 tgaggctctc ttggctaagg acaaggaagt acagctctta gaaaatcagt tggctacctt
    53701 gcgtttggag catgaaaatc aactacaaaa gaccctttct gacctagaaa aagaacggga
    53761 tcaggttaaa aaccaactac ttttgcagga aaaggaaaat gaattatctt tggcttctgt
    53821 taagcaaaac tacgaagccc agctcaaggc agctagtgaa caagtcgagt tttataagaa
    53881 ttttaaggct caacaatcta caaaagcgat tggggaaagc ctagaacagt atgcagagag
    53941 tgagtttaac aaggttcgta gtttcgcctt tccaaatgct tactttgaga aggataacaa
    54001 ggtctcttcg cgtgggtcta aaggggactt tatcttccgt gagtgtgatg aaaatggagt
    54061 tgaaatcatt tctatcatgt ttgagatgaa aaacgaagcg gacggaacag agaagaagca
    54121 caagaatgca gatttttaca aggaattgga caaggaccgt cgggagaaga actgtgagta
    54181 tgccgttttg gtgaccatgc ttgaggctga taatgactac tttaacacag ggattgttga
    54241 cgtcagtcac gagtatgaaa aaatgtatgt tgttcgtcct caattcttta tccaattgat
    54301 tggtctctta cgtaatgcgg cgctaaattc cctaaaatac aagcaggagt tggccttggt
    54361 tcgcgagcaa aatattgaca ttacgcattt tgaggaagat ttggatgcct ttaagctagc
    54421 ttttgctaag aactataatt cagcttcgac taactttgga aaagctattg atgaaatcga
    54481 caaggccatc aaacgcatgg aagaggttaa gaaattcctg accacatctg aaaaccaact
    54541 ccgtttagct aacaacaaat tggaagatgt ctctgttaaa aaattgaccc ggaaaaatcc
    54601 aacaatgaaa gcgaagttcg aagcactgaa gggggagtag aaagcaaaaa tgaacggtat
    54661 tattaactta aaaaaggaag caggaatgac ctcgcatgat gcggttttta aactgcgtaa
    54721 gattttggga accaagaaaa ttggtcatgg tggaaccttg gatccggatg tggtgggtgt
    54781 tttgccgatt gcggttggca aggcgacacg catggtcgag tttatgcagg acgagggtaa
    54841 gatctatgag ggggaaatca ctctgggcta ttccacgaag actgaggatg ctagtgggga
    54901 agtggtcgca gaaacccctg ttttgtctct cttggatgaa aagcttgttg atgaagcgat
    54961 tgctagcttg actgggccta ttactcagat tccccctatg tattcggcag ttaaggttaa
    55021 tggtcgcaag ctctatgagt atgcgcgtgc tggtcaggaa gtggagcgtc cagaacgtca
    55081 ggtgaccatt tatcaatttg agcgaacaag tccgatttct tatgatggcc aacttgcccg
    55141 attcactttt cgtgtaaaat gcagtaaagg gacgtacatc cgtactttgt cagttgattt
    55201 gggtgaaaag cttggttatg cggctcatat gtcccatttg actcgtacta gtgctgctgg
    55261 cttacaatta gaagacgctc ttgccttgga ggaaattgct gaaaaagtag aggctgggca
    55321 attagatttt ctccatcctt tagagattgg gacaggtgac cttgtcaaag ttttcctaag
    55381 tccagaagag gctacagaag ttcgctttgg tcgttttatt gagctagacc aaacggacaa
    55441 agaactggct gcctttgaag atgataaatt gttagccatt ctagaaaaac ggggcaatct
    55501 ctataagcca aggaaggttt ttagctagat cgtttaggaa taaaaatcgg gtgatagata
    55561 acaattgctt gataaaaccc catactaata gtagaatggt tttgggaatt ataatattcc
    55621 aattgttgcg agttgtaggt actcaaataa tctatataga aatttagagg tgtgaaatga
    55681 agcaatttaa aattctttca gataaatatt tagagtccat tacaggttct gatgggaact
    55741 taggcccagg atttggtgtg ataattccat gatgcgaaat gagtttcgag aaagggtgga
    55801 gcaacttctt caacaaaaag aaataaatga aaatagtgag ttgagtcacc tgtttcgtct
    55861 tgctatacaa aatttagaca gaaatgaaaa ataccaatcg gtcatggcca atttgagtca
    55921 agggttgtca ctttacctca tgacgcatca ttaccaggca cctaagtctg tcattgattt
    55981 tggtttatgg attgccaaag ctcctagcca ggaaagaggg agactggctt tcttgcagat
    56041 gcttgctcaa accctacagg gctttcgtta aaactgtcga acatcagagg gaagactctg
    56101 gtgttttttg ctgatgagac tataaatttt gtaaaaaatg tgatagaata gacgacggat
    56161 aaaataacgg aggatagcat gcaaaataga ccaatcatta ttggagtgac aggtggttct
    56221 ggtggtggta aaaccagtgt ttcaagagcc attttatcgc attttcctga tgaaaagatt
    56281 tccatgattg agcatgattc atactacaag gatcagtctc atttgacctt tgaagagcgt
    56341 gtcaaaacca actatgacca tccttttgcc tttgatacag acttgatgat cgagcagatt
    56401 aaggaattgt tggcagggcg tccggtggac atcccgacct acgactatac agagcataca
    56461 cggagtagca agacctatcg tcaggaacct caagatgtct ttatcgttga gggtattttg
    56521 gtcttggagg acaagcgtct gcgcgatttg atggatatca agatttttgt ggatacggat
    56581 gacgatgtgc gcattattcg tcgtatcaag cgtgatatgg aggagcgtgg ccgtagcctt
    56641 gatagcgtta ttaaccagta cttaggtgtg gtcaaaccaa tgtaccacca gtttatcgag
    56701 tcaactaagc gttatgctga tatcgtcatt cctgaagggg ttagcaatac cgtggctatc
    56761 gacctgttga cgaccaagat tgcaaagatt ttggaagaag ctcgaaacag caaataatca
    56821 catgtggagg ccttgcctcc tttttctatt tttccctcat aatggtacat aaatggagat
    56881 ttttaggcat atttttggta taataatacc catgaaagag caagtaaatg aatagtaggt
    56941 ggagatggaa aagtatttat cggtaacaac tttgaccaag tatctgaaaa tgaaattcga
    57001 taaagaccca tacttggaac gggtctattt aactggtcaa gtttccaact ttcgtaaacg
    57061 acctactcac caatatttct ccctaaagga tgaccatgca gttattcaag cgaccatctg
    57121 gtctgggatt tatcagaaat tagggtttga cctggaagaa ggaatgaaga tcaatgtgat
    57181 tgggcgtgta caggtctatg aaccaagtgg tagctactcc atcatcattg aaaaagctga
    57241 gcctgatggg gttggggcgc ttgcgattca gtttgaacaa cttaagaaaa aattgacaga
    57301 agaaggcctg tttcaagaac gcttcaagca agctctgccc caattttcta agagaattgg
    57361 tgtagtaacc agccgtagtg gagccgttat tcgagatatt atcacgaccg tcagcaggcg
    57421 attcccaggt gttgacatcc ttctttatcc gaccaaggtt caaggtgaag gggctgcgga
    57481 ggaaattgct agaaatattg cgcgtgctaa tcaacgggac gatttggatt tgctcattat
    57541 tggtcgtgga ggtggttcta ttgaggatct ctgggccttt aacgaagaaa ttgtggtacg
    57601 agctattttt gaatctcgtt tgccagttat ctctagtgtg gggcatgaga cggatgtgac
    57661 cttggcagat tttgtggcag atcgacgcgc tgcaacgcca acagcggcgg ctgaactggc
    57721 aacacctgtg accaagttgg atgtattagc tcatttgcaa aatcaggaaa aacggatggt
    57781 aacggcagtc cgaaatgttc tatctaagaa acaagaggct ttgaaaaaat gcagtcagtc
    57841 tgttatcttt agacaacctg agcgcttgta tgacggttat ttgcaacgct tggaccaact
    57901 gcaactgcgt ttgaaacaaa gtttgcgaac tcggatttct gataacaaac aattagttca
    57961 agcaagaact catcaattag tacaattatc acctgttacc aaaatccaac gctatcaaga
    58021 ccgtttagga cagttggaca agctcttagg tagccaaatg gcgttagttt atgacgccaa
    58081 ggttgctgag gccaagcgac tttcggaagc tttgctcatg ttggatacta gccgaatcgt
    58141 ggcgcgtggt tatgctattg tcaaaaaaga agagtccgtt gtagattcgg ttgagagttt
    58201 gaagaaaaaa gaccaagtaa cgcttttgat gcgagatggt caagtagaat tagaggttaa
    58261 agatgtcaaa acaaaagaaa tttgaggaaa atctagcaga actggaaacc attgtccaaa
    58321 gtttggaaaa tggtgaaatt gctctggaag atgcgattac tgcctttcaa aagggcatgg
    58381 tcttgtcaaa agagctccaa gctacgctgg acaaggctga aaagaccttg gtcaaggtca
    58441 tgcaagaaga cggaacagaa agtgattttg aatgaaaaag caagaaaaat tagctcttgt
    58501 cgagtcggct ttggaagatt tttatggaga ccagcagttt gcctctagtt tacgggagtc
    58561 tgttctctat tctattcatg ctggtggcaa gcgtattcgg ccttttctct tgttagaagt
    58621 tctggaagcc ttgcaggtta ccatcaaacc tgctcacgcg caggtagcta ctgccttaga
    58681 gatgattcat acagggagct tgattcacga tgaccttcct gctatggatg atgacgatta
    58741 tcgaagaggg cggttaacca atcacaagaa attcggtgaa gctatggcca ttttggctgg
    58801 agatgcctta ttcttagact catatgcctt gattgcgcag gcagatttgc caagtcagat
    58861 taaggtggac ttgattgcca acttatccct tgcttcaggt agtctgggta tggtagcagg
    58921 gcaagttttg gatatggagg gcgaacacca gcacttgtct ttggaagaac ttcagactat
    58981 tcatgccaat aagactggga agttactagc ctatcccttc caagcggcag ctattatagc
    59041 tgaattgtca cctgaaatgc aggtgaagct gaaaactgtg ggtgaattga ttggacttgc
    59101 ttttcaagtc agagatgatg tactggatgt gacagctagt tttgaggaaa tcggcaagac
    59161 acctcaaaag gatctgcagg cagaaaaatc aacctatcct gccctgttgg gcttggaaga
    59221 gtccattgcc ttttgtaacc aaaccctgga tcaagctaat gaaaaattag aagaaattgc
    59281 ccagcagctt ccctttgaaa cagaatcgat tgtaagtgta gtagaaagtt tgagaatcaa
    59341 tggctaagga aagagtggat gtactagctt ataaacaggg gttgtttgaa acgagagagc
    59401 aggccaagcg aggtgtgatg gctggcctag tcgtagcagt ccttaatgga gaacggtttg
    59461 acaagccagg agagaaaatt ccagatgaca ccgaattaaa actcaagggg gagaaactca
    59521 agtatgtcag ccgtggtggt ttgaaactgg aaaaggcctt gcaggtcttt gatttgtcgg
    59581 tggatggcgc gactacgatt gatatcgggg cctctactgg aggttttacc gatgtcatgc
    59641 tacagaatag tgccaagttg gtctttgcag tcgatgttgg taccaatcag ttggcttgga
    59701 aattacgcca agacccacga gttgtcagca tggagcagtt caatttccgc tatgctgaaa
    59761 agactgattt cgagcaggag ccgagctttg ccagtattga tgtgagtttc atttccctta
    59821 gtctgatttt gccagccttg caccgtgtct tggctgatca aggtcaggtg gtagcacttg
    59881 tcaaacctca gtttgaggca ggacgtgagc agattgggaa aaatggaatt attcgagatg
    59941 ctaaggttca tcagaatgtc cttgaatctg taacagctat ggcagtagag gtaggttttt
    60001 cagtccttgg cttggacttt tctcccatcc aaggtggaca tggaaatatt gaatttttag
    60061 cgtatttgaa aaaagaaaag tcagcaagca atcagattct tgctgagatt aaagaagcag
    60121 tagagagggc gcatagtcaa tttaaaaatg aataaaaaag agagacttga aaaaattaga
    60181 agattggtga cagattatca aatcggcacg caagaagaaa ttgtagaaca tttgaaagaa
    60241 gcaggtatca ctgccactca ggcgacggta tcccgagata tcaaagagtt aggtattgtc
    60301 aaaattcctt tgagagacaa cacctatgtc tacgaattgc caaaatcaat cgtaaaaagt
    60361 ctgcaactgg ctgaagacaa tatcgaatcg gctgaattga tggataagat gatcaatctc
    60421 caagttattc caggaaatac ggcttttgta aaagctcagt taatcgagac ttttgcagac
    60481 aagattttta gctgtttgac tgatgatagc tcgattttag tcattgccag aagtggaagt
    60541 ctagcagagg aaatctttga acaagtaaaa aattggtagg tctatatgtt acttgaaatt
    60601 tcgataaaaa actttgccat tattgaggct atttccctca attttgaaaa ggggatgact
    60661 gtcctgactg gtgaaacggg tgcagggaag tcgattatca ttgatgccat gaatatgatg
    60721 ttgggagctc gtgcgacgac agatgttatt cgtcatggtg caccaaaggc agagattgag
    60781 gggcttttct cagttgagaa tagtcgtctt ttacaggaaa tttttgatga gcaaggttta
    60841 gaattaggtg atgaaattat catccgtcgg gaaatcttgc aaaatggtcg tagtatcagc
    60901 cgtgtaaatg gtcagatggt taatctgtct gttttgcgag ctattgggca acatcttgta
    60961 gatattcatg gtcagcatga ccatgaggag ttaatgcgtc cccaactgca tatccagatg
    61021 ttggatgaat ttggtgatgc cgctttttgg gacttgaaag aaacctatca aacgagtttt
    61081 gatgcctatc ggaaaatgcg caagcaggtt ctggaagtca agaaaaacca acaggaacac
    61141 aaggcacgta tcgaaatgtt ggaatttcaa atggcagaga ttgaggcagc aaacttgcag
    61201 gctggagaag acttggctct caatcaagag cgagataaac tcctcaacca caaaaatatt
    61261 gcggatacac tgaccaatgc ctacagtatg ttggacaatg aagatttttc aagtctggcc
    61321 aatgttcgtt cagctatgaa tgacatggaa agtgtcgaag agtatgatcc tgaataccgt
    61381 gaaatttcaa gctatctgtc tgagacctac tatgttttag aagacattag caaacgtttg
    61441 gaagctatca ttgaggacct tgattttgat ggcaatcgcc tgatgcaggt tgagaatcgt
    61501 ttggacctcc ttcatactat tactcgtaag tatggtggga ctgttgatga tgttttgctt
    61561 tattttgcca agattacgga agaatacaat ctcttgacag gcaataatct ttcgtctgag
    61621 gacatggaag cagagcttaa gaagttggaa gtcaatcttg tcaatttggc aggtcaactt
    61681 gcttctgctc gtcataattt ggctcagcaa ctcgaagctg agattaaaca agaactgcaa
    61741 gatctttata tggaaaaagc ccagtttcag gttcgtttta gtaagggaaa attcagtcgt
    61801 gagggaaata aaatggttga gttttatatt tcaaccaacc ctggagaaga ctttaaaccc
    61861 ttggttaagg ttgcttctgg aggggaatta tctcgtctca tgttagccat taagtctgcc
    61921 ttttcacgta aagaaggcaa gactagcatt gtctttgatg aggtggatac gggagtttca
    61981 ggtcgtgttg ctcaagctat tgctcagaaa attcataaaa ttggtcagca tggtcaggtt
    62041 ttggctatct cccatttgcc acaagtaatt gcgattgcag attatcaatt ctttattgag
    62101 aagattagta atgaccattc aacggtttcg actgttcgtc tcttgacggt cgaagagcga
    62161 gtggaggaag ttgccaagat gttggcaggt gatgatgtga cagaagcagc cctgacgcaa
    62221 gcaagagaat tgttgagaaa cagggagaaa taagatgaca gattattatg taattggaga
    62281 tgttcacgga aaagctggga tgctggaaga ccttctcaaa acctgggatg gtcagcccca
    62341 gttgctcttt ctaggtgatt tgattgacag aggtgaggat agtcaccgtg ttcttgaaat
    62401 ggtcaaggac ttggtggaca atcaaggggc tatctgtttg tccggaaacc acgagtatat
    62461 gtttttgact tggctagatg acccagaaga aagttatgac cattatagtc gcaatggtgg
    62521 agatacaacc attaactcta tcctaggtcg tcccttggat gcaccagttg atggagtaga
    62581 agatgccaag cgggttgccg ctgaagcggc agacttggtc gaattcattc gtcaaatgcc
    62641 atttgtagta gagacagaca agtatatctt tgttcacgca ggtattgatt tgaccttgga
    62701 cgactggcat gaaacaacag attataaaaa agtatggctt agaaaaccat tccacggagc
    62761 tgaaaatcat actggaaaaa ccattgtctt cggtcataca ccggtctatg gtttgttaca
    62821 gcaagaacgc ggtacatctg agctttggac tacagaagat ggcaagattg gaatggatgg
    62881 aggagctgtt tatggtggtg tccttcacgg gattgtcttt acagaccaag gaatgacaga
    62941 acaccacttt atcgaaaatg acggctttgt cgctgaagat tagtactcct agcagggtat
    63001 ggtcttgtca aaatatcaaa aacaatttat aataaataga taccctgaaa ggaagagaat
    63061 catgaactta gaagaattga aaaaacgaca ggagaagatc cgtaacttct ctattatcgc
    63121 ccatattgac cacggaaaat caactctagc agaccgcatt ttggaaaaaa cagagacggt
    63181 ttcaagtcgt gaaatgcagg cccagctttt ggatagcatg gagctagagc gggaacgtgg
    63241 aattactatt aagttgaatg ccatcgagtt gaattacact gcaaaagatg gggaaactta
    63301 tattttccac ttgattgaca caccagggca cgttgacttt acctatgaag tttcacgttc
    63361 gctagctgcc tgtgagggtg ctattttggt ggtcgatgcg gctcaaggaa ttgaggctca
    63421 aactcttgcc aacgtttatc tggctttgga taatgatttg gaaatcatgc ctatcattaa
    63481 taaaattgac ctgccggctg cagatccgga gcgcgtgcgt acagagattg aagatgtgat
    63541 tggtttggat gccagtgaag cagttttggc ttctgccaag gctggtattg ggattgaaga
    63601 aatcctcgag caaattgtag aaaaagtacc agcaccaacg ggtgatgtga cggcgccact
    63661 taaggccttg attttcgact ctgtttacga tgcttaccgt ggggttatcc tccaagtgcg
    63721 tgtcatggac ggagtggtca aacctggtga taagattcag ctcatgagca atagtaagac
    63781 ctttgatgtg gccgaagtcg gtatttttac accaaaagcg gttggtcgtg atttccttgc
    63841 gactggtgat gttggttaca ttgcggcgtc tatcaagacg gttcaggata ctcgtgtggg
    63901 tgataccgtt accttggcaa ccaatcctgc ggcagaacca ttacatggtt ataagcagat
    63961 gaatcctatg gtctttgcgg gtctctaccc aatcgaatca aacaagtaca atgacctgcg
    64021 tgaagcgctt gaaaaattgc aactgaatga tgctagtctt cagtttgaac cagaaacatc
    64081 tcaggcactt ggatttggtt tccgttgtgg atttcttgga cttctccata tggatgttat
    64141 ccaggaacgt ttagagcgtg agttcaatat tgacctcatc atgacagctc cgtctgttat
    64201 ttacaaagtt aatttgaccg acggtgagtc tatggatgtg tctaacccat ctgagtttcc
    64261 agacccaact aagattgcga ccattgaaga gccttatgtc aaggcgcaaa tcatggtacc
    64321 acaggagttc gtcggagcag taatggagct agctcagcgt aagcgtgggg actttgtgac
    64381 tatggactat attgatgata accgtgtcaa tgttatctat caaattcctc ttgctgaaat
    64441 tgtctttgac ttctttgata aacttaagtc ttcgacacgt ggttatgcaa gctttgacta
    64501 cgaattgtca gaatatcgcc catctaagct ggtgaaaatg gatattcttc tcaatggaga
    64561 taaggtggat gccctcagct ttatcgttca caaggacttt gcctacgaac gtgggaaact
    64621 catcgttgat aaactcaaga aaatcatccc tcgccaacaa tttgaagttc caatccaagc
    64681 ggctattgga cacaagattg tcgctcgtac tgatatcaag gcccttcgta agaacgtact
    64741 tgctaaatgt tatggtggtg acgtttctcg taagcgtaaa ctccttgaaa aacaaaaagc
    64801 tggtaagaaa cgcatgaaat ccatcggatc agttgaagtt ccgcaagaag ccttcctcag
    64861 cgtcttgagt atggatgaag aataagttat cagaaatgcc tttccttgtt cacaggaaat
    64921 ttatataaga atcaatagta aagcaggctt agatggtctg cttttttagt ttttatactc
    64981 ttcgaaaatc tcttcaaacc acgtcagcgt cgccttaccg tatgtatggt tactgacttc
    65041 gtcagtttca tctacaacct caaaaccatg ttttgagctg acttcgtcag tttcatctac
    65101 aacctcaaaa ctgtgttttg aacaacctgc ggctagcttc ctagtttgct ctttgatttt
    65161 cattgagtat tagaacagaa aaatgcttgg agtatttgtt tgtgtgttta tttttatata
    65221 acaaactata aacaaaacaa aaatataaaa aaagagacaa aaaagaatag aaagtaatta
    65281 acaacgattt catatagtgt tatacttata gcataaagtt aatggaaaga agggaaaacc
    65341 ttatggtatt agattatttc tttgacaaaa accttgtgtt ttgcttagaa gcggataatc
    65401 aagaataact ttttgatcag gtagcaagct tgttggaaga acgagaaatt gtcactccaa
    65461 cttatcgtga agccttgatc acgcgtgaaa agtcatttcc aactggttta tatatggaat
    65521 ttctaggaaa ggacttgcaa atgtaatgat tcctcacaca gatattgttc ataatctagc
    65581 tgagaaagtg gtggttgttc gattagagaa accggtgact ttccataata tgattgcgcc
    65641 aggtaaggaa gtagaagtat ccttgctctt ctttatcatc aataattcaa gttcaagtca
    65701 aacgaacatt cttgctcagt taatggactt cttcacagga aatggtcatc ttgaagacct
    65761 atcaaaaatt tctgaaccag aagcccttta tgcttacatt gctgaagcaa ccgcttaatc
    65821 ttgtctatta aaaaataaaa tcggaggaaa tccaaatgat taaaattctt gctgcctgcg
    65881 gtgcaggtgt taactcaagt caccaaatta aaagtgctct agaagaagaa ctttcaaacc
    65941 gtggttacga tgttcactgt gatgcagtta tggtgaaaga tgtaaacgaa gaccttatga
    66001 aaggttacga tatctttaca ccaatcgctg caacagacct tggttttgaa ccaggtatcc
    66061 cagttatcga agctgggcca atcttattcc gtatcccagc aatgagcgtt ccagtatttg
    66121 acaatattag acttcctgcg aaacaaaaca tggtatagta gttctatgaa tgatgaagca
    66181 agtaaacaac taactgatac acgatttaaa tgtcttgttg gtgttcagcg cacgactttt
    66241 gaagagatgt tagctgtgtt aaaaacagct tatcaactta aacacgcaaa aggtggacga
    66301 aaacctaaat taagcctaga agaccttctt atggccactc ttcactatgt gcgagaatac
    66361 cgcacttatg aagaaattgc ggctgatttt ggtatccacg aaagcaactt actccgtcgg
    66421 agccaatggg ttgaagtaac tcttgttcaa aggtggtgtt acgatttcaa gaactcctct
    66481 cagttctgaa gacacggtaa tgattgatgc gacggaagta aaaatcaatc gacctaaaaa
    66541 aagaattagc gaattattct ggtaaaaaga aatttcacgc tatgaaggct caagcgattg
    66601 tcacaagtca agggagaatt gtttctttgg atatcactgt gaactattgt catgatatga
    66661 agttgttcaa aatgagtcgc agaaatatcg gacaagctgg taaaatcttg gctgacagtg
    66721 gttatcaagg acccatgaag atatatcctc aagcacaaac tccacgtaaa tccagcaaac
    66781 tcaagccgct aacagttgaa gataaagcct ataaccatgc gctatctaag gagagaagca
    66841 aggttgagaa catctttgcc aaagtaaaaa cgtttaaaat gttttcaaca acctatcgaa
    66901 atcatcgtaa acgcttcgga ttacgaatga atttgattgc tggtattatc aatcatgaac
    66961 taggattcta gtttttcagg aagtctaata aagaaactag caaggtcagg ccttacttta
    67021 ttggtggaca tccaggattt aattgtcctc tacttgatga tgaagtctat gaagattatt
    67081 atctagagtt tgagaaagaa gagatttgct ctgttccacg tcctttccca gaaacaggta
    67141 tgttggattt ccaagataga agtccatggc tagagggaca aaaagaaata gatcttagtt
    67201 atgatctttt cagcacagat gcagtgactt tggatgaatt gcaatctcga acaattgccc
    67261 ttcgttctct taaacatgat aagggattga aagtgcattt tgcagaattt ccaaacctca
    67321 tcatctggtc aactttgaac aagggacctt tcattacctt tgaaccatgg tctggcttgt
    67381 caacatccct tgaagaagga gatcatttag aagataagaa gaatgtttgt ctcttagaag
    67441 ccaatcaggt tgaagaatta gggtttgaga tagaagtttt ataaaaaagt aaaaaataaa
    67501 taacaaaaac aaacaaaagc tgttgacttc ttcaaacaat agtagtatat taggtttgtg
    67561 aggactaatt gactgttttt taaagacagt caatacactg ctggaatcca gcatagaaaa
    67621 aataaaaagg agtatacaat atgtctattg ttatcggtgc agatgctgca ggtttgagat
    67681 tgaaagaagt tgtgaaagac ttcttagaaa aagaaaactt ccaccttgtg gatgttacag
    67741 ctgaaggtca agactttgtt gatgtgactc tcgctgttgc tgcagaagta aacaaagaag
    67801 aacaaaacct tggtatcgtg attgatgctt atggagctgg tccatttata gttgcaacta
    67861 agatcaaagg aatggttgct gcagaagtat ctgacgaacg ttcagcttat atgactcgtg
    67921 gccacaacaa ctcacgtatg atcactatgg gagcacaact tgttggtgat gaattggcta
    67981 aaaatatcgc taaaggattt gttaatggta aatacgacgg tggtcgtcac caaatccggg
    68041 ttgacatgtt gaacaaaatg ggctaattag attatagtaa gaaaggtaag ttaaaaatga
    68101 gaattgcaat tggatgtgac cacatcgtaa ctgatgaaaa aatggcggtt tcagaatttt
    68161 tgaaatcaaa aggatatgaa gtcattgact ttggtaccta tgaccataca cggactcact
    68221 acccaatctt tggtaaaaaa gtaggggaag ctgtaactag cggtcaagct gatcttggag
    68281 tatgtatctg tggtactggt gttggtatca acaacgctgt aaataaagtt ccaggtgttc
    68341 gttctgcctt ggttcgtgat atgacaacag ccctttatgc taaagaacaa ttgaacgcta
    68401 acgttattgg ttttggtggt aaaattactg gtgaattgct tatgtgtgat atcatcgaag
    68461 ctttcatcca tgctgaatac aaaccaactg aagaaaacaa aaaattgatt gcgaaaattg
    68521 aacatgttga aagtcacaat gctcaacaaa cagacgcaaa cttctttaca gaattccttg
    68581 agaaatggga tcgtggagaa taccacgact aagaggtgac ctatgatttt aacagtcaca
    68641 atgaacccat ccatcgatat ttcctatccc ttggatgagt tgaagattga tactgtcaat
    68701 cgtgtggtgg atgtaaccaa aacggctggt ggtaagggac tcaatgttac ccgagtactt
    68761 tcagaatttg gcgattctgt tcttgctact ggtttagtgg gtggcaaact tggtgagttt
    68821 ttggttgaac atatcgataa tcaagtaaag aaagatttct tctcaattaa gggagaaact
    68881 cgtaactgta tcgctattct ccacggagac aaccaaacag aagttcttga aaaaggtcct
    68941 gaagtattgg aacaggaagg tcaagagttt ttggaacatt tcaaaaaact cttggagtca
    69001 gttgaagtag tagccatctc aggtagtctg ccagctggcc ttccagttga ttactatgcg
    69061 agcttggtag aacttgctaa tcaagctggc aagcatgtag tcttggactg ctcaggtgca
    69121 gcacttcagg ctgttcttga atcaccccat aaaccaacag tcatcaaacc aaataatgaa
    69181 gaattgtctc agcttcttgg aagagaagtt tctgaggatt tggatgaatt aaaagaagta
    69241 cttcaagaac ctttgtttgc agggattgaa tggattatcg tttcacttgg tgccaacggt
    69301 acttttgcca aacatggtga cactttctac aaggtagata ttcctagaat tcaggtggta
    69361 aatcctgttg gatctggaga ctctactgtg gcaggaattt cttcaggact tcttcacaaa
    69421 gaatcggatg cagaattact catcaaggca aatgtccttg gtatgctcaa tgctcaagaa
    69481 aaaatgactg gtcatgtcaa catggccaac tatcaagctc tatatgatca attaatagta
    69541 aaagaggtat aaaatggctt taacagaaca aaaacgtgta cgcttagaaa aactttctga
    69601 tgaaaatggt atcatctcag ctcttgcatt tgaccaacgt ggtgctttga aacgcctcat
    69661 ggttaaacac caaacagaag aaccaactgt ggcccaaatg gaagaactta aagtcttggt
    69721 agcagatgaa ttgactaaat atgcttcatc tatgcttctt gaccctgagt atggacttcc
    69781 agcaactaaa gctcttgatg aaaaagctgg tcttctcctt gcttatgaaa aaacaggtta
    69841 tgacacaaca agcacaaaac gcttgccaga ctgcttggat gtttggtctg caaaacgtat
    69901 taaagaagaa ggtgcagatg cagttaaatt cttgctttac tatgatgtag atagctcaga
    69961 cgaactcaat caagaaaaac aagcctacat cgaacgcatc ggttctgagt gtgtggctga
    70021 agatatccca ttcttccttg aaatccttgc ttacgatgaa aaaattgcgg atgcaggttc
    70081 tgtagaatac gctaaagtaa aaccacacaa agttatcggc gctatgaaag tcttttcaga
    70141 cccacgcttt aacattgatg ttttgaaagt tgaagttcct gttaacatta aatatgttga
    70201 aggcttcgct gaaggtgaag tagtttatac acgtgaagaa gcagcagcct tcttcaaagc
    70261 gcaagatgaa gcaacgaact tgccatacat ctacttgagt gctggtgtat cagctaaact
    70321 cttccaagat actcttgtat ttgctcatga atcaggtgcg aactttaacg gagttctttg
    70381 tggccgtgct acatgggcag gatcagttga agcttacatc aaagatggtg aagcagcagc
    70441 tcgcgaatgg cttcgcacaa ctggatttga aaacattgac gaactcaaca aagttcttca
    70501 aagaacagca acttcatgga aagaacgcgt gtaagaaagt cctcctagtt taggaacatg
    70561 aatctaaaaa aatttaaaaa aagttgtatg taaaggctta caaaataact tacttgtgct
    70621 atacttaaat cacaagttaa tatgaattag aaagtaacta tatgaagtat aataaaaata
    70681 ggatatagtt tattttacga gctaggaagg aaaaatacgg aaacaatatt gccagaataa
    70741 actatattta gatgcacatt tcattcattg ttttataaaa ggagaagata aacggctact
    70801 aaaaagagtt ttaaagcgtt agttgtagga ctaggtattg tttcaatatt cttatcagcc
    70861 ttacctatgg ttagtggttc tgtatttgca gatagtgccc taactacagt agataaagca
    70921 aatgatattg ttttgaatgt tgatgggaat aaattttata atgtttcggt ttcagaagat
    70981 attgtaaatg ctggtcaaat tttggaagat tatttttatg tagataaatt tggaaatata
    71041 aatttaaaag gcactcctga agagttagca aaaaatattg gtatttctgt acaagaagca
    71101 agtttgatgt atggagctgt aaaagagtta cccaacgttt acgaaagagg tcctgtaggt
    71161 tttcgtttca atcttggtcc tcaagtgagg gggatgggtg gctgggctgc tggagctttc
    71221 gctactggat atgctggatg gcatttgaaa caatttgcgg ttaatcctgt tacatctgga
    71281 tttgttgctg taataagtgg tgcgattggc tgggctgtaa aaactgctgt agaaaattat
    71341 tggacagttg ctgtagctac agtagaagtg ccgtttgtga accttgttta caccatagat
    71401 ttaccttaga ggttatttct ttatgaatca ttcttttaaa aaaataactg tattttgttt
    71461 tatagtttct tgtgttcttt gtttattaga cttaatgaat tttaaaaatg tagctacttt
    71521 tttatttttc tgtcttcctg tttttgtttt gatttacaaa aataaataaa aacagagcct
    71581 ctgtttgatg aattttagaa catagttaag ttttaaaaaa agttgtatgt aaaggtttac
    71641 aaaataactt acttgtgcta tacttaaatc acaagttaat acaaggtgag tgttactaag
    71701 taatattagg catgatcaca ggtgaattag aaatcagctg attttctagt tcatttgtgg
    71761 tcattttttg tacttatata cctttaagat ataaaaggag gttgacatgt atcgaattct
    71821 aaatccaatg aatcacaatg tctcgcttgt cagaaatgat aagggagaag aggtgattgt
    71881 aattggtaag ggaattgcat tcggaaagaa gaagggggat ttgattgctg aaaatcaggt
    71941 tgagaaaatc tttcggatga agaccgaaga gtccagagaa aactttatgg ctcttctcaa
    72001 agatgttccg cttgatttta tcacagtgac ctatgaaatc attgataagc tatcaaagaa
    72061 atatcattat ccgattcaag agtatctcta tgtaaccttg acagatcata tttactgttc
    72121 ttatcaagct ctaactcaag gaaggtacaa ggatagtaat ctgccagata tttccgctaa
    72181 gtatcctgtc gcttttcaaa tcgcaaatga agcttttgaa atttaccgtc agaagctagc
    72241 agatcatttt cctgaggacg aaattattcg gattgcttat catttcatta atgctgaagg
    72301 tgaaaatgaa gtggaacttg tggagtcgat tgataagagg aaagaaattc tcaggaatgt
    72361 tgaagaagtt ttaacggact atgcaattca acgaactaaa aagaataacc atttctatga
    72421 tcgctttatg atccatttga attatttctt ggattattta gacagatcta gagatgataa
    72481 ccaatcactt ctggatatgg aagatcatat taaacaatcc tatccaaaag ccttcgagat
    72541 tggttccaag atctatgatg tgattacgca acatacgggt cttgatttgt ataaaagtga
    72601 acgagtttat ctagttctac atatccaacg tttattgtca taaaaattta tttaaaacta
    72661 tataaggaga attctatcat gaatagagaa gaagtaacat tgttaggttt tgaaatctta
    72721 gcctatgctg gcgatgctcg ttcaaaacta ttggaagcct tgaaggctgc tgaagctggt
    72781 gattttgaaa aagcggacgc tctggtagag gaagctggta gctgtattgc agaggctcac
    72841 cacgcgcaaa caagtctatt gactaaggaa gcttcaggtg aggacttggc ttatagtgta
    72901 accatgatgc atggccaaga ccacttaatg acaactatct tgttaaaaga tttgatgcat
    72961 catttaattg aactctacaa gagaggagtt caataatgaa taaactaatt gcatttatcg
    73021 agaaaggaaa gcctttcttt gaaaaactat ctcgtaatat ctatcttcgt gctattcgtg
    73081 atggtttcat tgcaggtatg cctgttattc tcttctcaag tatctttatc ttgattgcct
    73141 ttgtaccaaa ctcatggggc tttaaatggt ctgatgaagt tgtagccttt ctgatgaaac
    73201 cttatagcta ttctatgggt attctggctc tcttggtagc tggtacaaca gctaagtcat
    73261 tgactgactc agtaaaccgg agcatggaaa aaaccaatca aatcaactat atgtcaacat
    73321 tgttggcagc tgatcctatc gaaagtggtc tagctactgg attcttgggg acaaaaggtt
    73381 tgctttcagc cttccttgct gcctttgtta ctgtagccat ctataaggtt tgtgttaaga
    73441 acaacgtcac tattcgtatg cctgacgaag ttccaccaaa tatctcacaa gtctttaaag
    73501 atgtgattcc attcactcta tctgttgttt ctctttatgc tcttgactta ttagcacgtt
    73561 attttgttgg ttctagtgtg gcagaatcaa tcggtaaatt cttcgcacca ctcttctcag
    73621 cagcagacgg ataccttggt attaccatta tctttggtgc ctttgccttc ttctggtttg
    73681 ttgggattca tggtccatct atcgttgaac cagctatcgc agctattacc tatgccaatg
    73741 ccgaagttaa cttgaacctt ctccaacaag ggatgcatgc agacaagatt cttacttctg
    73801 gtacacaaat gtttatcgtt accatgggtg gtacaggtgc gacattggtc gttccattta
    73861 tgttcatgtg gttgacaaaa tcgaaacgta accgtgcaat cggacgtgct tcagtagttc
    73921 ctaccttctt cggtgtaaat gaaccaatct tgtttggtgc acctcttgtt ttgaatccaa
    73981 tcttcttcat tccatttatc tttgctccaa ttgcaaacgt atggattttc aaattcttta
    74041 ttgaaactct tggaatgaac tcattcactg ctaatctacc atggacaact ccagctccac
    74101 taggtctagt tcttggaact aacttccaag tgctatcatt cattcttgct gcccttctaa
    74161 tcgtggttga cgttgtcatt tactatccat tccttaaggt ctatgatgaa caaattcttg
    74221 aagaagaacg ttcaggtaag tctaatgatg aattgaaaga aaaagttgct gcaaacttca
    74281 acactgcaaa agcggatgct attcttgaaa aagcgggtgt cgatgcagca caaaatacca
    74341 tcactgaaga aacaaatgtc ctcgttctct gtgcaggtgg aggaacaagt ggtctccttg
    74401 caaatgcttt gaataaggca gcagcagaat acaatgtccc tgtgaaagca gcagcaggcg
    74461 gctatggtgc tcaccgtgaa atgttaccag agtttgatct tgttatcctt gcccctcaag
    74521 ttgcttcaaa ctttgaagat atgaaagcag aaacagataa gctcggtatt aaactagcga
    74581 aaacagaagg cgctcaatac atcaaattaa ctcgtgatgg aaaaggtgct cttgcattcg
    74641 tacaagcgca attcgattaa ggctagagac tctgaaatag tctcccatcg ttacggaaat
    74701 cgctatggcg aatttcctat tattaattcg tcggtaaaaa gatatcgttt ttacctcctc
    74761 atgtcacaat tcggtgactt ggtacaagaa gtgagatgga gaaggatggc tcactgactc
    74821 ctctcctctc acttttactt tatttaaatc aagaaatagg tgaaaaaaat gacaaaaaca
    74881 cttccaaaag actttatttt tggtggcgca acagctgctt atcaagcaga aggtgctaca
    74941 catactgatg gaaaaggacc agttgcttgg gataaatatc ttgaggataa ctactggtac
    75001 actgccgaac cagctagtga tttttacaat cgatatccag ttgacctcaa gctagcagaa
    75061 gagtatggtg tcaatggtat tcgaatttct attgcttggt cacgtatttt cccgactggt
    75121 tacggccaag taaatgctaa aggtgttgag ttttatcata atttatttgc agagtgtcac
    75181 aaacgtcatg ttgagccttt tgtaactctt catcactttg acacgccaga agctctccac
    75241 tcaaatggag acttcttaaa ccgtgaaaat atcgaacatt ttgtagacta cgctgccttc
    75301 tgttttgaag aatttccaga agtaaactat tggacaacct ttaatgaaat tggaccaatc
    75361 ggtgatggtc aatatttggt tgggaaattc cctccaggta tccagtacga ccttgccaaa
    75421 gtctttcaat cacaccacaa tatgatggtg tctcatgcac gcgcggtaaa attgtacaaa
    75481 gagaaaggct ataaagggga aattggtgtt gttcacgccc tgccaactaa atatcctcta
    75541 gatcctgaaa atccagcaga tgttcgtgca gctgagttgg aagatatcat ccacaataaa
    75601 ttcatcttag acgcaactta tctaggtcgc tattcagctg aaaccatgga aggtgtcaac
    75661 catatcttat tagtcaatgg tggtagtttg gatcttcgtg aagaagattt tacagcatta
    75721 gaagctgcaa aagacttgaa tgatttccta ggaatcaact actatatgag tgactggatg
    75781 gaagcctttg atggagaaac tgaaattatc cataatggta aaggtgaaaa aggaagctct
    75841 aagtatcaaa tcaaaggtgt tggtcgtcgt gtagctcctg actatgtacc acgcacggat
    75901 tgggattgga ttatctaccc tcaaggtttg tatgaccaaa tcatgcgtgt gaagaaagat
    75961 tatcctaact acaagaagat ttacatcact gaaaatggtc tcggctataa agatgagttc
    76021 gttgataaca ctgtttacga tgatggtcgt attgattacg tgaagcaaca cttggaggtt
    76081 ttatctgatg cgattgcaga tggagctaat gtaaaaggtt acttcatttg gtcattaatg
    76141 gatgtcttct catggtcaaa cggttatgag aaacgttatg gtctcttcta cgtagatttt
    76201 gaaactcaag aacgttatcc taagaaatca gctcactggt acaagaaagt agcggaaact
    76261 cagattatag actagtagaa ttagtcatta gatatagaat tttagtgagt caaaaagatg
    76321 ttcaaagatt ttatccaatc tatttatgaa aaaaagttta tattataaat ttcgaaaaat
    76381 gctctcaaat accgtgtttg acgagtgaag aattgaaaag tcttggaaaa tggtatgtct
    76441 cgactggtaa agaatggatt tgtcattcag atgatgagct ggaagaattt aaaaatctat
    76501 ttttaaattt tatcaatcct gaagaatggg atactatctc ctttgattca gattttatgc
    76561 cgtttcaaca atcgtaacca atttctcaaa aaagttaaat cttatattta gtactctgta
    76621 aaactcttat ctaatcacgt tgcttatact caatgaaaat caaagagcaa ctttaaacta
    76681 ggaagcgagt cgcagatttc tcaatgcata gctttgagga attgggcaaa aagtctttga
    76741 tatagaaaaa cgcatagtat caggtgtttc aacacctgat actatgcgtt ttattgtggg
    76801 aagatttact ttttttcttc tgaaattgag ttgttaccca ggctctttca gtttattaag
    76861 gcttgatgac tttaatgtgt ttagatagct taaaaaggat tgaatcactt agtttagaat
    76921 ctgaaacaat agtatcaaga tttgatacat tataaaaagt ataaaaatca aacttattga
    76981 acttgctatg atctgcgagt aaatattttt tattagaatt atttaaagcg atgcgttgag
    77041 cctctccctc ttcctcgcta aaagtagcta gagctccgtt ttgaatacca ttacagctaa
    77101 cgaaagcttt agaaaattgg agattagaga gattttgtag ggtcaatgta ccaacaaaag
    77161 cacctgtaat atcgcgataa tttccaccta ttaaaatcaa atctgttaat tttcgttcgc
    77221 ttaaaatcag aaaaacaggt agactgttgg ttacgacgcg gatattgtca ataggcaact
    77281 cacgcgcaaa aaactctaat gttgttcctg gtccaatgaa aatagtttct ctttcttcta
    77341 ctagactgcc tgcaaaatgg gctatttctt gtttttctgc cgtttggagg gcttgttttt
    77401 caatatttga tcgctcatta gtcaaaaggg agttggttcg aagtttttca gctccaccat
    77461 gcacacgaat cagcaaatct ttatcagcta attcctgtaa atagcgcctt gcagtcatat
    77521 ctgaaacggc tatttcgtcc ataatctgtt taactgttat ggttccttta ctatttacta
    77581 tctctaaaat tttggttaat ttttcttgtt tgagcatatt atcacctcgt ttcctactac
    77641 tatcttacca taaactagct catcattcaa atacaaaaac aacaaaataa aacaaaaaca
    77701 aaaatatcga ggtttatttt caaaactttc gatattttta ttaagttatt attttgttgt
    77761 ttctagttta ctttttgatg gttaagagtg gtggagaatt atactcaatg aaaatcaaag
    77821 agcaaactag gaagctagcc gcaggctgta cttgagtacg gcaaggcgaa gctgacgtgg
    77881 tttgaatttg attttcgaag agtattagtg caaaccgtag ttgtagtcat catcttgcat
    77941 ggcttcaact tcgccaagaa ggtaaccatt tccgacttga gagaagaagt catggttgga
    78001 agttcctgtt gaaataccgt tcataacgat tgggttgaca tcttcagctg aatctgggaa
    78061 aagtggatct tgtcccatgt tcatgagagc tttattggca ttgtagcgaa ggaaggtttt
    78121 aacctcttca gtccaaccaa caccgtcata aagactctct gtgtagcctt cttcattttc
    78181 ataaagagta tagagtaggt cgtacatcca ttctttgagt ttttcttgct cttcttcagg
    78241 taattcattg aaaccaagtt ggaatttgta accaatgtag gttccgtgaa cagactcgtc
    78301 acgaataatc aatttaatga tttctgcaac gttggcaagt ttgttgttac cgagatagta
    78361 gaggggagtg aagaaaccag agtagaagag gaaggtttcg aggaagacgc tggcaacttt
    78421 cttttcaagt gggctgccgt ttaggtagat ttcgttgaca atctcagcct tcttttgtag
    78481 gtaaggattg gtattggtcc attcgaaaat ttcttcaatc tcagccttag tattcaaggt
    78541 agaaaagatt gatgagtaag atttagcgtg gacagattcc ataaattgga tgttattgaa
    78601 gacagcttcc tcatgtggtg tacggatgtc tgcgcgaagg gcttgaaccc cagtttcaga
    78661 ttgcatagtg tcaagaaggg ttaaaccacc aaaaactttt ccgaccaagt ctttctcttt
    78721 gttagatagc tttctccagt catccaagtc gtttgataag ggaatacgtg tatcgagcca
    78781 aaattgctcc gtcagttttt cccaagttga tttgtcgatg acatcttcga tggcattcca
    78841 gttaatggct ttgtagtaag tttccattta aaatctcttt ctgtgtttag tattgcgaac
    78901 tcacaattat ttctacttta ccataattct ataggagtat cgcacaaaaa gtcggaagcc
    78961 cgacttttaa aatgttacat aaattatgtt atgacatagt agatttgatt ttatcagtgc
    79021 tgcttaggga aaaatagtgt ttctatgcta gaaactaaat cacacagctt tcacattggt
    79081 tggcgccgac ttctccaccg tcatctgtaa aggtacggac gtagtagata gacttgattc
    79141 ccttgttaaa ggcatagtta cgaaggatgg acaagtcacg tgtcgtttgt ttattttccc
    79201 tcttccattc gtaaaggcct tttggaatgt cactgcgcat gaagagggtg agtgaaagtc
    79261 cttgatccac gtgttcagtc gcagcagcgt aaacatcgat gactttacgc atatccatat
    79321 cgtaggcaga agtgtagtaa ggaatggttt ctgtagacaa gccagcagca gggtaataga
    79381 ttttaccaat tttcttctct tggcgttctt cgatacgttg cgtaatcggg tggatagaag
    79441 cagaaacgtc gttgatatag ctgatagaac catttggcgc tacagcaagg cgattttggt
    79501 ggtaaagacc atcttcttga accttgtcgc gaagttcagc ccaatcagca acaccaggga
    79561 taaagacatt tttgaagagt tctttaacac ggtctgatgt tggaacaaat tcaccagtta
    79621 catacttgtc aaagtaactt ccgttagcat agtctgattt ttcaaagttg tggaaggtaa
    79681 taccacgttc acgtgcaata ttgtttgact ctaccaaggt ccagtagttc ataagcataa
    79741 agtagatgct tgtaaattca acagactcag gtgaaccata ttcaatgagt tgttgggcaa
    79801 ggtagctgtg cagtcccatg gcaccgagac caaaggtgtg ggcttggcta tttccatggt
    79861 caatcgttgg tacagctacg atatgtgaac tatctgtaac gaaagtaagg gcacgaacca
    79921 tagcacggat agaacgacca aaatcaggtg aagtcatcat gttaaccacg ttggttgaac
    79981 ccaggttaca tgaaacatct gttcccattt gaaggaattc ttgagcatcg ttgatcaagc
    80041 ttggttcttg aacttgaaga atctcagaac acaagttact catgataatc tttccatcaa
    80101 caggatttgc acggttagcc gtatcgatgt tgactacata aggatagcca gactcttgtt
    80161 gcaatttaga gatttcagtt tccaaatccc gcgccttgat ttttgtcttg cgaatatttg
    80221 gatttgcgac caattcatcg tatttttcag taatgtcgat gtaattgaat ggcacaccgt
    80281 attctttttc tacagagtaa gggctgaaga ggtacatttc ttcattttta cgagccaatt
    80341 cgtagaattt atcaggtact acaacaccaa gtgatagagt cttgacacgt actttttcat
    80401 cagcgttttc tttcttagtt gaaaggaaag cgatgatatc tgggtgaaag acgttgaggt
    80461 agacaacacc agcaccttga cgttgcccca attggttgga gtaagagaag ctgtcttcaa
    80521 aaagcttcat aacaggaacg acacctgaag cagctccttc atagcctttg ataggtgcac
    80581 cagcttcacg aaggttgctg agggtaattc ccacaccacc accaatacgt gaaagttgaa
    80641 gagctgagtt gatagaacgc ccgatagagt tcatatcatc cgtcacttgg attaggaaac
    80701 aagataccaa ctccccacga cgagcacgtc cagcattcaa gaaggaagga gtagcaggtt
    80761 ggtagcgttg gtggatgatt tcattggcaa tatcgattgc aacagcttca ttcccatcag
    80821 cgaaataaag ggcattgaag aagacacggt cttccatatt ttcaagatag tattcaccgt
    80881 cattagtctt taaggcatat tgattgtaaa atttataagc tgccatgaat gacttgaatt
    80941 ggaagttttg gtctttgata aattgagcta attcttccaa gaactctgga cggtatttct
    81001 tgataaaggc tgtttcgatg tagttgtgtt caatgaggta attgattttg tctttgattg
    81061 aatcaaaaac catagtgttt ggaactacat tttctttaaa gaaagcatcc aaggcttcct
    81121 tgtctttatg aagcatgatt tgtccattaa caggacggtt aatttcgtta ttaagacgga
    81181 agtaagtcac gtcttcaaga tgttttaatc ccataaaatt tcccttatct aattacaaaa
    81241 gaaaggcttc taagttagcc ctaaaagcag tttcttctgg atgatgtact aagattatgc
    81301 taattgtttc agttttcctg gttggaaacc tgaaaagact tcagttggtg tttggataac
    81361 aggagctgcg ctaaaaccga gctctttaac ttgatcgacg tactcaggtt gctcatcaag
    81421 attgatttca cgataagaga cattattact gtccaagaaa cgcttggtca ttttacattg
    81481 gacacaattg tttttagaat aaacggttac cattgtgtaa ctcctcttca aaatttaata
    81541 ctatcttagt atatcagaaa ataaaatttt gtcaatgatt tgaactaaat atagtggtgt
    81601 tcttttgttg tttttatata taaacacaat atatagtgtt tgtattgtga aatagcaatg
    81661 attatcctat aaattgtttt taaagaaact atatcctgtg ttttgttatc taggatagaa
    81721 gattttcagc aagttatctg aaaggaaatt gaaggaaaat ccagaaaatg cttgaaaaaa
    81781 atcctagaag atggtataat actaaattgt aagggttatc acatataact caaaaaaaga
    81841 aagaacaaaa ggagagtcaa actatggctt ctaaagattt ccacgtagtg gcagaaacag
    81901 gtattcacgc acgtccagca acattgttgg tacaaactgc tagcaaattt gcttcagata
    81961 tcactcttga gtacaaaggt aaatcagtta accttaaatc aattatgggt gttatgagtc
    82021 ttggtgttgg ccaaggtgct gacgtaacta tctcagctga aggtgcagat gcagatgacg
    82081 ctatcgctgc aatctcagaa acaatggaaa aagaaggatt ggcataaggg aaatgacaga
    82141 aatgcttaaa ggaatcgcag catctgacgg tgttgcagtt gcaaaagcat atctactcgt
    82201 tcagccggat ttgtcatttg agactattac agtcgaagat acaaacgcag aagaagctcg
    82261 ccttgatgcc gctctacagg catcacaaga cgagctttct gttattcgcg agaaagcagt
    82321 aggtacgctc ggtgaagaag cagctcaagt ttttgatgct cacttaatgg ttcttgctga
    82381 cccagaaatg atcagccaaa tcaaggaaac tatccgtgcg aagaaagtga atgcagaagc
    82441 aggtctgaaa gaagttacag atatgtttat cactatcttt gaaggcatgg aagacaaccc
    82501 atacatgcaa gaacgcgcag cggatatccg cgacgtgaca aaacgtgtat tggcaaacct
    82561 tcttggtaaa aaattgccaa acccagcttc tatcaatgaa gaagtgattg tgattgcgca
    82621 tgacttgact ccttcagata cagctcaatt ggacaaaaac tttgtaaaag cttttgtaac
    82681 caacattggt ggacgtacaa gccactcagc tatcatggca cgtacacttg aaattgctgc
    82741 tgtattaggt acaaataaca tcactgaaat cgttaaagac ggtgacatcc ttgctgttaa
    82801 cgggatcact ggagaagtga ttatcaaccc aacagatgaa caagcggcag aatttaaagc
    82861 agctggtgaa gcctatgcga aacaaaaagc tgaatgggca cttttgaaag atgctcaaac
    82921 agtgactgct gacggtaaac acttcgagtt ggctgctaat atcggtactc caaaagacgt
    82981 tgaaggtgtt aacaacaacg gtgcagaagc tgttggactt taccgtacag agttcttgta
    83041 catggattct caagacttcc caactgaaga tgagcagtat gaagcataca aggctgttct
    83101 tgaaggaatg aacggtaaac ctgttgtcgt tcgtacaatg gatatcggtg gagataagga
    83161 acttccttac ttcgatatgc ctcacgaaat gaacccattc cttggattcc gtgctcttcg
    83221 tatctctatc tctgagactg gagatgctat gttccgcaca caaatccgtg ctcttcttcg
    83281 tgcgtctgtt cacggtcaat tgcgtatcat gttcccaatg gttgcgctct tgaaagaatt
    83341 ccgtgcagcg aaagcagtct ttgatgaaga aaaagcaaac cttcttgctg aaggtgttgc
    83401 agttgcggat aacatccaag ttggtatcat gatcgagatt cctgcagcgg ctatgcttgc
    83461 agaccaattt gctaaagaag ttgacttctt ctcaattggt acaaacgact tgatccaata
    83521 tacaatggca gcagaccgta tgaacgaaca agtttcatac ctttaccaac catacaaccc
    83581 atcaatccta cgcttgatta acaatgtgat caaagcagct cacgctgaag gtaaatgggc
    83641 tggtatgtgt ggtgagatgg ctggtgacca acaagctgtt ccacttcttg tcggaatggg
    83701 cttggatgag ttctctatgt cagcaacatc tgtacttcgt acacgcagct tgatgaagaa
    83761 actcgacaca gctaagatgg aagagtacgc aaaccgtgcc cttacagaat gctcaacaat
    83821 ggaagaagtt cttgaacttc aaaaagaata cgttaatttt gattaatcga aaagtccctg
    83881 caactcagtt acagggattt ttttgatatt ttaaaaagaa ttttcaagaa aatctttctt
    83941 atagaaagtc caaccttgaa aaagtagtgg tcagaacaaa aaatacttaa atggttcata
    84001 aaattcttga caagttggat atttaggagt aaactattaa ccagttaagt aatagagagg
    84061 agtttctgca atttagaaat gaattgcaac tagaaatatc aaatagaaag agagtttcga
    84121 tgaaaattaa taagaaatac cttgttggtt ctgcggcagc tttgatttta agtgtttgtt
    84181 cttacgagtt gggactgtat caagctagaa cggttaagga aaataatcgt gtttcctata
    84241 tagatggaaa acaagcgacg caaaaaacgg agaatttgac tcctgatgag gttagcaagc
    84301 gtgaaggaat caatgctgag caaatcgtca tcaagataac agaccaaggc tatgtcactt
    84361 cacatggcga ccactatcat tattacaatg gtaaggttcc ttatgacgct atcatcagtg
    84421 aagaattact catgaaagat ccaaactata agctaaaaga tgaggatatt gttaatgagg
    84481 tcaagggtgg atatgttatc aaggtagatg gaaaatacta tgtttacctt aaggatgctg
    84541 cccacgcgga taacgtccgt acaaaagagg aaatcaatcg acaaaaacaa gagcatagtc
    84601 aacatcgtga aggtggaact ccaagaaacg atggtgctgt tgccttggca cgttcgcaag
    84661 gacgctatac tacagatgat ggttatatct ttaatgcttc tgatatcata gaggatactg
    84721 gtgatgctta tatcgttcct catggagatc attaccatta cattcctaag aatgagttat
    84781 cagctagcga gttggctgct gcagaagcct tcctatctgg tcgaggaaat ctgtcaaatt
    84841 caagaaccta tcgccgacaa aatagcgata acacttcaag aacaaactgg gtaccttctg
    84901 taagcaatcc aggaactaca aatactaaca caagcaacaa cagcaacact aacagtcaag
    84961 caagtcaaag taatgacatt gatagtctct tgaaacagct ctacaaactg cctttgagtc
    85021 aacgacatgt agaatctgat ggccttgtct ttgatccagc acaaatcaca agtcgaacag
    85081 ctagaggtgt tgcagtgcca cacggagatc attaccactt catcccttac tctcaaatgt
    85141 ctgaattgga agaacgaatc gctcgtatta ttccccttcg ttatcgttca aaccattggg
    85201 taccagattc aaggccagaa caaccaagtc cacaaccgac tccggaacct agtccaggcc
    85261 cgcaacctgc accaaatctt aaaatagact caaattcttc tttggttagt cagctggtac
    85321 gaaaagttgg ggaaggatat gtattcgaag aaaagggcat ctctcgttat gtctttgcga
    85381 aagatttacc atctgaaact gttaaaaatc ttgaaagcaa gttatcaaaa caagagagtg
    85441 tttcacacac tttaactgct aaaaaagaaa atgttgctcc tcgtgaccaa gaattttatg
    85501 ataaagcata taatctgtta actgaggctc ataaagcctt gtttgaaaat aagggtcgta
    85561 attctgattt ccaagcctta gacaaattat tagaacgctt gaatgatgaa tcgactaata
    85621 aagaaaaatt ggtagatgat ttattggcat tcctagcacc aattacccat ccagagcgac
    85681 ttggcaaacc aaattctcaa attgagtata ctgaagacga agttcgtatt gctcaattag
    85741 ctgataagta tacaacgtca gatggttaca tttttgatga acatgatata atcagtgatg
    85801 aaggagatgc atatgtaacg cctcatatgg gccatagtca ctggattgga aaagatagcc
    85861 tttctgataa ggaaaaagtt gcagctcaag cctatactaa agaaaaaggt atcctacctc
    85921 catctccaga cgcagatgtt aaagcaaatc caactggaga tagtgcagca gctatttaca
    85981 atcgtgtgaa aggggaaaaa cgaattccac tcgttcgact tccatatatg gttgagcata
    86041 cagttgaggt taaaaacggt aatttgatta ttcctcataa ggatcattac cataatatta
    86101 aatttgcttg gtttgatgat cacacataca aagctccaaa tggctatacc ttggaagatt
    86161 tgtttgcgac gattaagtac tacgtagaac accctgacga acgtccacat tctaatgatg
    86221 gatggggcaa tgccagtgag catgtgttag gcaagaaaga ccacagtgaa gatccaaata
    86281 agaacttcaa agcggatgaa gagccagtag aggaaacacc tgctgagcca gaagtccctc
    86341 aagtagagac tgaaaaagta gaagcccaac tcaaagaagc agaagttttg cttgcgaaag
    86401 taacggattc tagtctgaaa gccaatgcaa cagaaactct agctggttta cgaaataatt
    86461 tgactcttca aattatggat aacaatagta tcatggcaga agcagaaaaa ttacttgcgt
    86521 tgttaaaagg aagtaatcct tcatctgtaa gtaaggaaaa aataaactaa tgaaaaatga
    86581 aagtctcgat aaagaggctt tcatttttat tatgtatata tgtaaaattc ttgacaagca
    86641 atattaaaaa gagtaaacta ttaactagtt aattaaccgg tttattactt tatagtgaat
    86701 caaatatact taagaaaaga ggaaagaatg aaaattaata aaaaatatct agcaggttca
    86761 gtggcagtcc ttgccctaag tgtttgttcc tatgagcttg gacgttacca agctggtcag
    86821 gataagaaag agtctaatcg agttgcttat atagatggtg atcaggctgg tcaaaaggca
    86881 gaaaacttga caccagatga agtcagtaag agggagggga tcaacgccga acaaattgtt
    86941 atcaagatta cggatcaagg ttatgtgacc tctcatggag accattatca ttactataat
    87001 ggcaaggttc cttatgatgc catcatcagt gaagagctcc tcatgaaaga tccgaattat
    87061 cagttgaagg attcagacat tgtcaatgaa atcaagggtg gttatgtcat taaggtaaac
    87121 ggtaaatact atgtttacct taaggatgca gctcatgcgg ataatattcg gacaaaagaa
    87181 gagattaaac gtcagaagca ggaacgcagt cataatcata actcaagagc agataatgct
    87241 gttgctgcag ccagagccca aggacgttat acaacggatg atgg
//
LOCUS       DAVFER010000002        84625 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1105170250
            SAMEA2167659-rid19724873.denovo.002, whole genome shotgun sequence.
ACCESSION   DAVFER010000002 DAVFER010000000
VERSION     DAVFER010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2167659
            Sequence Read Archive: ERR388902
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 84625)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 84625)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928716.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928716.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 04:07:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,118
            CDSs (total)                      :: 2,073
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 120
            CDSs (without protein)            :: 120
            Pseudo Genes (ambiguous residues) :: 0 of 120
            Pseudo Genes (frameshifted)       :: 67 of 120
            Pseudo Genes (incomplete)         :: 47 of 120
            Pseudo Genes (internal stop)      :: 34 of 120
            Pseudo Genes (multiple problems)  :: 23 of 120
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..84625
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2167659-rid19724873.denovo.002"
                     /strain="1105170250"
                     /db_xref="taxon:1313"
     gene            complement(196..273)
                     /locus_tag="VU534_000084"
                     /pseudo
     CDS             complement(196..273)
                     /locus_tag="VU534_000084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            344..1000
                     /locus_tag="VU534_000085"
     CDS             344..1000
                     /locus_tag="VU534_000085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001141648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HEU1512745.1"
                     /translation="MPTALGYVSIGLACGIIGAPYVTPVEMGLMSLFVYAGSAQFAML
                     ALIVVQAPVAAIAMTVFLINLRLFLLSLYASTYFRHTSLWYNIGMSSILTDETYGVLM
                     GELAHTDKVNPMWMHGNNLNSYVAWFVGTVVGTALGGLLPNPEIFGLDFALVGMFIGI
                     FASQFQIMQRRIPVRNLLIILAVVAVSFFLLLTVMSQSLAVLFATLLGCSMGVVLDGQ
                     "
     gene            990..1199
                     /locus_tag="VU534_000086"
     CDS             990..1199
                     /locus_tag="VU534_000086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000253940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HEU1512746.1"
                     /translation="MVSKYLLLAVIFSGLVTWIPRMIPFILVKYKGLPAIVERFLKFL
                     PVSIIFALILSSVVTGKVGSLPQIK"
     gene            1417..2247
                     /locus_tag="VU534_000087"
     CDS             1417..2247
                     /locus_tag="VU534_000087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEU1512747.1"
                     /translation="MKKIVKYSSLAALALVAAGVLAACSGGAKKEGEAASKKEIIVAT
                     NGSPKPFIYEENGELTGYEIEVVRAIFKDSDKYDVKFEKTEWSGVFAGLDADRYNMAV
                     NNLSYTKERAEKYLYAAPIAQNPNVLVVKKDDSSIKSLDDIGGKSTEVVQATTSAKQL
                     EAYNAEHTDNPTILNYTKADFQQIMVRLSDGQFDYKIFDKIGVETVIKNQGLDNLKVI
                     ELPSDQQPYVYPLLAQGQDELKSFVDKRIKELYKDGTLEKLSKQFFGDTYLPAEADIK
                     "
     gene            2401..3255
                     /locus_tag="VU534_000088"
     CDS             2401..3255
                     /locus_tag="VU534_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000694494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HEU1512748.1"
                     /translation="MKIKKWLGLAALATVAGLALAACGNSEKKADNATTIKIATVNRS
                     GSEEKRWDKIQELVKKDGITLEFTEFTDYSQPNKATADGEVDLNAFQHYNFLNNWNKE
                     NGKDLVAIADTYISPIRLYSGLNGSANKYTKVEDIPANGEIAVPNDATNESRALYLLQ
                     SAGLIKLDVSGTALATVANIKENPKNLKITELDASQTARSLSSVDAAVVNNTFVTEAK
                     LDYKKSLFKEQADENSKQWYNIIVAKKDWETSPKADAIKKVIAAYHTDDVKKVIEESS
                     DGLDQPVW"
     gene            3355..4728
                     /locus_tag="VU534_000089"
     CDS             3355..4728
                     /locus_tag="VU534_000089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HEU1512749.1"
                     /translation="MVFPSEQEQIEKFEKDHVAQHYFEVLRTLISKKSVFAQQVGLKE
                     VANYLGEIFKRVGAEVEIDESYTAPFVMAHFKSSRPDAKTLIFYNHYDTVPADGDQVW
                     TEDPFTLSVRNGFMYGRGVDDDKGHITARLSALRKYMQHHDDLPVNISFIMEGAEESA
                     STDLDKYLEKHADKLRGADLLVWEQGTKNALEQLEISGGNKGIVTFDAKVKSADVDIH
                     SSYGGVVESAPWYLLQALQSLRAADGRILVEGLYEEVQEPNEREMALLETYGQRNPEE
                     VSRIYGLELPLLQEERMAFLKRFFFDPALNIEGIQSGYQGQGVKTILPAEASAKLEVR
                     LVPGLEPHDVLEKIRKQLDKNGFDKVELYYTLGEMSYRSDMSAPAILNVIELAKKFYP
                     QGVSVLPTTAGTGPMHTVFDALEVPMVAFGLGNANSRDHGGDENVRIADYYTHIELVE
                     ELIRSYE"
     gene            4721..5782
                     /locus_tag="VU534_000090"
     CDS             4721..5782
                     /locus_tag="VU534_000090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000085652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein"
                     /protein_id="HEU1512750.1"
                     /translation="MSRDIIKLDQIDVTFHQKKRTITAVKDVTIHIQEGDIYGIVGYS
                     GAGKSTLVRVINLLQKPSAGKITIDDDVIFDGKVTLTAEQLRRKRQDIGMIFQHFNLM
                     SQKTAEENVAFALKHSELSKEEKKAKVAKLLDLVGLADRAENYPSQLSGGQKQRVAIA
                     RALANDPKILISDESTSALDPKTTKQILALLQDLNQKLGLTVVLITHEMQIVKDIANR
                     VAVMQDGHLIEEGSVLEIFSNPKQPLTQDFISTATGIDEAMVKIEKQEIVEHLSENSL
                     LVQLKYAGASTDEPLLNELYKHYQVMANILYGNIEILDGTPVGELVVVLSGEKAALAG
                     AQEAIRQAGVQLKVLKGVQ"
     gene            5784..6476
                     /locus_tag="VU534_000091"
     CDS             5784..6476
                     /locus_tag="VU534_000091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU1512751.1"
                     /translation="MESLIQTYLPNVYKMGWAGQAGWGTAIYLTLYMTVLSFIIGGFL
                     GLVAGLFLVLTAPGGVLENKVVFWILDKITSIFRAVPFIILLAILSPLSHLIVKTSIG
                     PNAALVPLSFAVFAFFARQVQVVLAELDGGVIEAAQASGATFWDIVGVYLSEGLPDLI
                     RVTTVTLISLVGETAMAGAVGAGGIGNVAIAYGFNRYNHDVTILATIIIILIIFAIQF
                     LGDFLTKKLSHK"
     gene            complement(6506..7075)
                     /locus_tag="VU534_000092"
     CDS             complement(6506..7075)
                     /locus_tag="VU534_000092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000748387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HEU1512752.1"
                     /translation="MKKSILTTLLFAVLYFLCMGIGVLLGNLFDQTGNMFYAPAFTAL
                     VGGSVYMILVAKVPRFGAITTIGLVIALFFLGTKHGAGSFLPGIICGLLADGVAHLGK
                     YKDKTKNFLSFIIFAFSTTGPILLMWIAPKAYMATLLARGKSQEYIDRIMVAPNPGTV
                     LLFIASIVIGALVGALIGQALSKKFAQKI"
     gene            7210..7824
                     /locus_tag="VU534_000093"
     CDS             7210..7824
                     /locus_tag="VU534_000093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000532354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HEU1512753.1"
                     /translation="MGRFLDFVFNRFFLGMIATAFFWLLTLAGGIILGLAPASATLMS
                     LYAEHGYSFREYSLKEAWSLYKQNFVSSNLIFYSFLGVGLVLTYGLYLLVQLPHQTIV
                     HLIATLLNVLVVALIFLAYTVSLKLQVYFALSYRNSLKLSLIGIFMSLAAVAKVLLGT
                     VLLVAIGYYMPALLFFVGIGMWHFFISDMLEPVYEIIHEKLATK"
     gene            7826..9472
                     /locus_tag="VU534_000094"
     CDS             7826..9472
                     /locus_tag="VU534_000094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013670288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEU1512754.1"
                     /translation="MKQFWLHTLLRTYSSVMIIIIASFAILLSYADWDSREKEAQRVA
                     QRVTARTVSEIEYYHRESTQIAQALVENQARIEGIYKYFSLSMPDYFYWQLERKASPY
                     ISVSLYENVDDLYVRNDFVTGVAIAFQDYKEVYVSTKDKRSGEKIRAEDFKPAGNSFA
                     IPVSDPVSDQDLGVIYISLDPAVLYHAIDNTRGHTPMAVTVTSPFDTEIFHMGETVDK
                     ESENWLVGLTSHGYQVQVAVPKNFVLQGTVTSSALIVGLSLLFIVILYLTLRQTFANY
                     QKQVVDLVESIQVIAQGEEGRRIDISEKDQELLLIAETTNDMLDRLEKNIHDIYQLEL
                     SQKDANMRALQAQINPHFMYNTLEFLRMYAVMQSQDELADIIYEFSSLLRNNISDERE
                     TLLKQELEFCRKYSYLCMVRYPKSIAYGFKIDPELENMKIPKFTLQPLVENYFAHGVD
                     HRRTDNVISIKALKQDGFVEILVVDNGRGMSAEKLANIREKLSQRYFEHQASYSDQRQ
                     SIGIVNVHERFVLYFGDRYAITIESAEQAGVQYRITIQDE"
     gene            9484..10770
                     /locus_tag="VU534_000095"
     CDS             9484..10770
                     /locus_tag="VU534_000095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000278884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU1512755.1"
                     /translation="MYKVLLVDDEYMVTEGLKRLIPFDKWDMEVVATASHADEALEYV
                     QENPVDVIISDVNMPDKTGLDMIREMKEILPDAAYILLSGYQEFDYVKRAMNLSVVDY
                     LVKPVDKVELGNLLEKIAGQLGERGKKSQTLSQELDEAGFVSYLGDKENWWIGLSKEK
                     QGSFTIPYYVLGQDWQIFISGHPLDGLVVTPFEAPYQEHFERWKLNAEKTLFYGSVNL
                     QQSESLFAYYEPIYRVIIQGNLNQIVEELNLLEKVVLENTPRVSITKQLFIQFVMDVF
                     HLFEHLKADDMTDIVKTIHAIQSFDELVSYIKETLISFFGQYRMNENVVSVLEVIGRD
                     YQKELSLKDISKALFINPVYLGQLIKRETDSTFAELLNKQRIKAAQQLLLSTSDSIED
                     ICYAVGYSNLGYFYKVFRKLCGKSPKAYRKQVETIL"
     gene            10822..11355
                     /locus_tag="VU534_000096"
     CDS             10822..11355
                     /locus_tag="VU534_000096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000729030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU1512756.1"
                     /translation="MKKKPIYLWVLLILSALISVPSLFGIVSPLPSKEALRAAQKQVA
                     GVNAQQLEDQLNYTYRVAEASHSIFNVALIVLSTILVVVAIVFLVRKNLQYANYTYVG
                     YVLLAIIGSIYGYVGLQDAVQLVQDESMRLTVSIGSKAVSIFYIVINVLFLALVFYKM
                     WRQQKALAEEEETEELT"
     gene            11433..11903
                     /gene="nrdI"
                     /locus_tag="VU534_000097"
     CDS             11433..11903
                     /gene="nrdI"
                     /locus_tag="VU534_000097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000849618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HEU1512757.1"
                     /translation="MKTISLVYISLSGNTESFVTRLKDYLLSQYKGIEVQKIHIKDLV
                     KEGKNFYEMDHPYVAFLPTYLEGGNGVDNGDVEILTTPVGDFIAYGNNASKCFGVVGS
                     GNRNFNNQYCLTAKQYSQRFGFPVLADFEMRGMLEDIKHVAAIIADLYELEKEN"
     gene            complement(12196..13458)
                     /locus_tag="VU534_000098"
     CDS             complement(12196..13458)
                     /locus_tag="VU534_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000075801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="divalent metal cation transporter"
                     /protein_id="HEU1512758.1"
                     /translation="MSQAISLNQSTWASKLKAMGPGILMATAAVGGSHIVSSTQAGGS
                     YGWSLLLLVILANVFKYPFFRFGAEYTADTGKTLVEGYAEKGKLYLWIFFILNVFSAM
                     VNTAGVAILCSAIIASAFPMIGLSITQWSLILVAIIWAMLLFGGYKLLDGMVKWIMSA
                     LTIATVLAVIIAAVKHPEYSSDFVEKTPWQMAALPFIVSLLGWMPAPIEISAINSLWS
                     AEKRKTVNFNTEDALFDFNTGYIGTAILAVFFVALGALIQYPTGQAVEAASAKYISQF
                     VGMYASVLGEWSRYLITFIAFLCIFGTVITVIDGYSRVNQESLRLLISQKEDNRKSLN
                     IWMTITAIIGIVIIKFFAGQVSTMLRFAMIGSFLTTPFFALLNYALVTRENKNLPSWL
                     KHLAIAGLIFLFGFAIFFIYALAIGKAG"
     gene            complement(13768..14226)
                     /locus_tag="VU534_000099"
     CDS             complement(13768..14226)
                     /locus_tag="VU534_000099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3021 domain-containing protein"
                     /protein_id="HEU1512759.1"
                     /translation="MKKQVFHDAATGVLIGLILSILFSLIYAPNTYAPLNPYSLIGQV
                     MDQHQVHGALVLLYCTLIWATIGMLFNFGNRLFSRDWSMLRATLTHFFLMLAGFVPLA
                     TLAGWFPFHWIFYLQLIIEFAIVYLIIWAILYKREAKKVDHINQLLEHRK"
     gene            complement(14223..14663)
                     /locus_tag="VU534_000100"
     CDS             complement(14223..14663)
                     /locus_tag="VU534_000100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000861967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU1512760.1"
                     /translation="MKVELQISETYEEEKLIVQAPQETEKVQKVIEFAENLDQREKIK
                     GKIDDQVYLVEIGKIQRFYIENRKVLAETASQTYSIDLRLYQVLKLLPTNFIQISQSE
                     IINIDSISHLKLTPNGLVEIFLKNESFTYSSRRYLKTIKEKLEL"
     gene            15096..15962
                     /locus_tag="VU534_000101"
     CDS             15096..15962
                     /locus_tag="VU534_000101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000537001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU1512761.1"
                     /translation="MGTLLATRLKNRRKELKMSQRELAEGICKQGQISRLESGEFTPG
                     ADFLNALAKKLKVSMDYFFDEQVVEKVEELSEFKKLAQTFITNRNYESLKYIYELENV
                     KAHRLSLADKIYMEWIKSLIDFYFYGQKEDAIVRLEGVLSQLSVSDLNYLQVSNTLFN
                     FYYDIGDLGRFNKIREKLEYQVNHLNLSTIEELELSIKFNYNVCRYLWLQKNIEEAIT
                     KITATIKQCKAYRTNYLLADLYLLMGNVSENFSSKSSVKEYFETAYFLYKLEENMSMT
                     LKVEHYIADITE"
     gene            16288..16846
                     /locus_tag="VU534_000102"
                     /pseudo
     CDS             16288..16846
                     /locus_tag="VU534_000102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358739.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase family
                     flavoprotein"
     gene            17067..18173
                     /locus_tag="VU534_000103"
     CDS             17067..18173
                     /locus_tag="VU534_000103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000608718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal-dependent decarboxylase"
                     /protein_id="HEU1512762.1"
                     /translation="MINKKIQQVVLESLQNFLNGNFISPCVVYDFGLLETVLDEFKNQ
                     IPVTFNYQLFYAVKANSNEKILEFLVDKIDGVDVASLSELDVAKKFFPPTQISVNGPA
                     FSYETLYNLIKKQYKVDINFLEHLQQFSPKESVGIRVTEPDELNNRMSRFGINICSDN
                     WTSNLQNPLITRLHFHFGEKDDKFIVKLDKILFKLQEINKLREVREINLGGGFMKLFM
                     ENRLKEFFLSLMEIYKKYDIDSTVTTIIEPGSAITSFSAYMITSPVNVSEVNEQQVIT
                     LDTSIYTNTLWFVPHIITTLNSSSKERYSTILYGNTCYEHDKYKMKVSLPRLTQNSSI
                     VFFPVGAYIKSNHSNLHRNDFMREVYLWTKNLTY"
     gene            18149..19540
                     /locus_tag="VU534_000104"
     CDS             18149..19540
                     /locus_tag="VU534_000104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1512763.1"
                     /translation="MDKKLDILDKVKEYLGNKTTQILDNQYKEFLKLNDIRRAFGISE
                     KVLNNSFNFTSKEFNDLINNENYLFEYACRIREEWRKKCFNHSYRFLCSPIITDDFLN
                     TKTLRSSQIEYKYERYLSKSSIGDRAVDGFVSFNTLTANGMSAIKLCLEILNSIFFKK
                     KIDLLYSTGYYETRFLLNNLAKSGISCYEVSNCELDKDKFYNVFMMEPNRADLTLQKT
                     DFKIVEYFVKYKNNSIKVVILDISYQGSNFKLVEFLEKFKFANVIIFVVRSLIKLDQM
                     GLELTNGGIIEVFIPNHLRKLKNFIEEEFNKFRNSHGANLSLYEYCLLDNSLTLKNDW
                     NYSDLVMKFTSNFYADIKDLFMENSDIEIIHEEGVPFVFLDLIGEGKKEYEMFFQWLN
                     FFYKQLGITLYARNSFGFRNLTVEYFGIIGTERYIFKICPGVYKGLSYYLMKFLLKSF
                     SNEYLKTTDEVNR"
     gene            19537..20715
                     /locus_tag="VU534_000105"
     CDS             19537..20715
                     /locus_tag="VU534_000105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000792992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEU1512764.1"
                     /translation="MKNLIKLLIIRLIVNLADSVFYIVALWHVSNNYSSSMFLGIFIA
                     VNYLPDLLLIFFGPVIDRVNPQKILIISILVQLAVAVIFLLLLNQISFWVIMSLVFIS
                     VMASSISYVIEDVLIPQVVEYDKIVFANSLFSISYKVLDSIFNSFASFLQVAVGFILL
                     VKIDIGIFLLALFILLLLKFRTSNANIENFSFKYYKREVLQGTKFILNNKLLFKTSIS
                     LTLINFFYSFQTVVVPIFSIRYFDGPIFYGIFLTIAGLGGILGNMLAPIVIKYLKSNQ
                     IVGVFLFLNGSSWLVAIVIKDYTLSLILFFVCFMSKGVFNIIFNSLYQQIPPHQLLGR
                     VNTTIDSIISFGMPIGSLVAGTLIDLNIELVLIAISIPYFLFSYIFYTDNGLKEFSIY
                     "
     gene            21140..21373
                     /locus_tag="VU534_000106"
     CDS             21140..21373
                     /locus_tag="VU534_000106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000623387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEU1512765.1"
                     /translation="MISIDLGGTNIKITVLSNDGEIETLWSITTDTSEKGSQIISDII
                     SSIKNKLTERNIPDSDLLGIGMGSCSSYFPCKS"
     gene            21656..23605
                     /gene="mutL"
                     /locus_tag="VU534_000107"
     CDS             21656..23605
                     /gene="mutL"
                     /locus_tag="VU534_000107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HEU1512766.1"
                     /translation="MSHIIELPEMLANQIAAGEVIERPASVVKELVENAIDAGSSQII
                     IEIEEAGLKKVQITDNGHGIAHDEVELALRRHATSKIKNQADLFRIRTLGFRGEALPS
                     IASVSVLTLLTAVDGASHGTKLVARGGEVEEVIPATSPVGTKVCVEDLFFNTPARLKY
                     MKSQQAELSHIIDIVNRLGLAHPEISFSLISDGKEMTRTAGTGQLRQAIAGIYGLVSA
                     KKMIEIENSDLDFEISGFVSLPELTRANRNYISLFINGRYIKNFLLNRAILDGFGSKL
                     MVGRFPLAVIHIHIDPYLADVNVHPTKQEVRISKEKELMTLVSEAIANSLKEQTLIPD
                     ALENLAKSTVRNREKVEQTILPLKENTLYYEKTEPSRPSQTEVADYQVELTDEGQDLT
                     LFAKETLDRLTKPAKLHFAERKPANYDQLDHPELDLASIDKAYDKLEREEASSFPELE
                     FFGQMHGTYLFAQGRDGLYIIDQHAAQERVKYEEYRESIGNVDQSQQQLLVPYIFEFP
                     ADDALRLKERMPLLEEVGVFLAEYGENQFILREHPIWMAEEEIESGIYEMCDMLLLTK
                     EVSIKKYRAELAIMMSCKRSIKANHRIDDHSARQLLYQLSQCDNPYNCPHGRPVLVHF
                     TKSDMEKMFRRIQENHTSLRELGKY"
     gene            complement(23930..24397)
                     /locus_tag="VU534_000108"
     CDS             complement(23930..24397)
                     /locus_tag="VU534_000108"
                     /EC_number="2.5.1.78"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6,7-dimethyl-8-ribityllumazine synthase"
                     /protein_id="HEU1512767.1"
                     /translation="MNTYEGNLVANNIKIGIVVARFNEFITSKLLSGALDNLKRENVN
                     EKDIEVAWVPGAFEIPLIASKMAKSKKYDAIICLGAVIRGNTSHYDYVCSEVSKGIAQ
                     ISLNSEIPVMFGVLTTDTIEQAIERAGTKAGNKGSECAQGAIEMVNLIRTLDA"
     gene            complement(24398..25603)
                     /locus_tag="VU534_000109"
     CDS             complement(24398..25603)
                     /locus_tag="VU534_000109"
                     /EC_number="3.5.4.25"
                     /EC_number="4.1.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP
                     cyclohydrolase II"
                     /protein_id="HEU1512768.1"
                     /translation="MEYRKIQEALEALQKGRLVLVIDDKDRENEGDLICSAQAATTEN
                     VNFMATYAKGLICMPMSESLANQLMLSPMVENNTDNHKTAFTVSIDYKETTTGISAEE
                     RGLTARMCVAEDITPSDFRRPGHMFPLIAKKGGVLERNGHTEATVDLLKLAGLKECGL
                     CCEIMNHDGKMMRTDDLIQFSKKHNIPLITIKELQEYRKVYDQLVERVSTVNMPTRYG
                     NFKAISYIDKLNGEHHLALIMGNIEDEANVLCRVHSECLTGDVLGSLRCDCGQQFDKA
                     MKMIVENGSGVLLYLRQEGRGIGLINKLKAYHLQDQGMDTLDANLALGFEGDLREYHI
                     GAKMLKDLGLQSLHLLTNNPDKVEQLEKYGITISSRISIEIEANPYDSFYLETKKNRM
                     GHILNMEEK"
     gene            complement(25623..26258)
                     /gene="ribE"
                     /locus_tag="VU534_000110"
     CDS             complement(25623..26258)
                     /gene="ribE"
                     /locus_tag="VU534_000110"
                     /EC_number="2.5.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000493842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin synthase"
                     /protein_id="HEU1512769.1"
                     /translation="MFTGIIEEIGKVERIQKDSRNCKLSIKASKILTDIHLGDSIAVN
                     GICLTVTHFNHQSFTVDVMNETWSRTALTLLKHGSEVNLERALSVNGRLGGHVVTGHI
                     DGTGKISSIKKDDNAVWYQINTQKEILDLIVEKGSITIDGISLTVAKVSKVNFSVSVI
                     PHTLEQTILKSKQVGSTVNLENDILDKYVQKLMDNSPKSEISKELLYQNGF"
     gene            complement(26243..27343)
                     /gene="ribD"
                     /locus_tag="VU534_000111"
     CDS             complement(26243..27343)
                     /gene="ribD"
                     /locus_tag="VU534_000111"
                     /EC_number="1.1.1.193"
                     /EC_number="3.5.4.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     diaminohydroxyphosphoribosylaminopyrimidine
                     deaminase/5-amino-6-(5-phosphoribosylamino)uracil
                     reductase RibD"
                     /protein_id="HEU1512770.1"
                     /translation="MSDSKYMKLAIKLAQKGAGYVNPNPMVGAVIVKDNHIIGQGYHE
                     FFGGPHAERNALKNCRESPVGATLYVTLEPCCHFGKTPPCIDAIIDSGITRVVIGSLD
                     CNPIVSGKGVKILEENNLQVTVGILENECLNLIKSFRKYITQHVPYVFMKYAMSMDGK
                     IATKTNQSKWITEEEARKHVHQLRHHVSAIMVGVNTVIQDDPLLTCRLEEGKNPIRII
                     CDTHLRTPLTSKIVKTANDIKTYIATSSEDKNKMKLYQNHGCEILSIKKKGNHIDLSS
                     LMQHLGNMQIDSLVLEGGSLMNWSALEQQIVDELKIYIAPKVFGGSAKFPVGGEGISL
                     PNDAIRLKPYAFSQIGNDYLIESEVIYPCSQE"
     regulatory      complement(27477..27591)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            27748..28341
                     /gene="ruvA"
                     /locus_tag="VU534_000112"
     CDS             27748..28341
                     /gene="ruvA"
                     /locus_tag="VU534_000112"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000271492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HEU1512771.1"
                     /translation="MYAYLKGIITKITAKYIVLETNGIGYILHVANPYAYSGQVNQEA
                     QIYVHQVVREDAHLLYGFRSEDEKKLFLSLISVSGIGPVSALAIIAADDNAGLVQAIE
                     TKNITYLTKFPKIGKKTAQQMVLDLEGKVVVAGDDLPAKVAVQASAENQELEEAMEAM
                     LALGYKATELKKIKKFFEGTTDTAENYIKSALKMLVK"
     gene            28351..28914
                     /locus_tag="VU534_000113"
     CDS             28351..28914
                     /locus_tag="VU534_000113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HEU1512772.1"
                     /translation="MTKRCSWVKMTNPLYIAYHDEEWGQPLHDDQVLFELLCMETYQA
                     GLSWETVLNKRQAFREVFHSYQIHSVAEMTDTELEAMLENPAIIRNRAKLFATRANAQ
                     AFLQLQAEYGSFDAYLWSFVEGKTVVNDVPDYRQAPAKTPLSEKLAKDLKKRGFKFTG
                     PVAVLSFLQAAGLVDDHENDCEWKGLK"
     gene            28911..29588
                     /locus_tag="VU534_000114"
     CDS             28911..29588
                     /locus_tag="VU534_000114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000987430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU1512773.1"
                     /translation="MMSNKNKEILIFAILYTVLFMFDGVKLLASLMPSAIANYLVYVV
                     LALYGSFLFKDRLIQQWKEIRKTKRKFFFGVLTGWLFLILMTVVFEFVSEMLKQFVGL
                     DGQGLNQSNIQSTFQEQPLLIAVFACVIGPLVEELFFRQVLLHYLQERLSGLLSIILV
                     GLVFALTHMHSLALSEWIGAVGYLGGGLAFSIIYVKEKENIYYPLLVHMLSNSLSLII
                     LAISIVK"
     gene            complement(29725..30756)
                     /locus_tag="VU534_000115"
     CDS             complement(29725..30756)
                     /locus_tag="VU534_000115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000255096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LD-carboxypeptidase"
                     /protein_id="HEU1512774.1"
                     /translation="MVSTIGIVSLSSGIIGEDFVKHEVDLGIQRLKDLGLNPIFLPHS
                     LKGLDFIKDHPEARAEDLIHAFSDDSIDMILCAIGGDDTYRLLPYLFENDQLQKVIKQ
                     KIFLGFSDTTMNHLMLHKLGIKTFYGQSFLADICELDKEMLAYSLHYFKELIETGRIS
                     EIRPSDVWYEERTDFSPTALGTPRVSHTNTGFDLLQGSAQFEGKILGGCLESLYDIFD
                     NSRYADSTELCQKYKLFPDLSDWEGKILLLETSEEKPKPEDFKKMLLTLKDTGIFAVI
                     NGLLVGKPMDETFHDDYKEALLDIIDSNIPIVYNLNVGHATPRAIVPFGVHAHVDAQE
                     QVILFDYNK"
     gene            complement(31011..31694)
                     /locus_tag="VU534_000116"
     CDS             complement(31011..31694)
                     /locus_tag="VU534_000116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1129 domain-containing protein"
                     /protein_id="HEU1512775.1"
                     /translation="MSQIDLQKLTKKNQEFVHIATQQFIKDGKTDAEIQTIFEEVIPQ
                     ILEEQSKGTTARSLYGAPTHWAHSFTVKEQYEKEHPKENDDPKLMIMDSALFITSLFA
                     LVSALTTFFAADQAFGYGLITLLLVGLVGGFAFYLMYYFVYQYYGPDMDRSQRPPFWK
                     SVLVILASMFLWLLVFFATSFLPASLNPVLDPLPLAIIGAALLALRFYLKKRLNIRSA
                     SAGPTRYQE"
     gene            complement(31706..32650)
                     /locus_tag="VU534_000117"
     CDS             complement(31706..32650)
                     /locus_tag="VU534_000117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HEU1512776.1"
                     /translation="MKQVFLSTTTEFKEIDTLEPGTWINLVNPTQNESLEIANTFDID
                     IADLRAPLDAEEMSRITIEDEYTLIIVDVPVTEERNNRTYYVTIPLGIIITEETIITT
                     CLEPLPVLDVFINRRLRNFYTFMRSRFIFQILYRNAELYLTALRSIDRKSEQIESQLH
                     QSTRNEELIELMELEKTIVYFKASLKTNERVIKKLTSSTSNIKKYLEDEDLLEDTLIE
                     TQQAIEMADIYGNVLHSMTETFASIISNNQNNIMKTLALVTIVMSIPTMVFSAYGMNF
                     KDNEIPLNGEPNAFWLIVFIAFAMSVSLTLYLIHKKWF"
     gene            32782..35613
                     /gene="uvrA"
                     /locus_tag="VU534_000118"
     CDS             32782..35613
                     /gene="uvrA"
                     /locus_tag="VU534_000118"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HEU1512777.1"
                     /translation="MQDKIVIHGARAHNLKNIDVEIPRDKLVVVTGLSGSGKSSLAFD
                     TLYAEGQRRYVESLSAYARQFLGNMEKPDVDAIDGLSPAISIDQKTTSKNPRSTVGTT
                     TEINDYLRLLYARVGTPYCINGHGAINASSVEQIVDKVLELPERQRLQILAPVIRKKK
                     GQHKSVIEKVQKDGYVRVRVDGEVYDVTEVPELSKSKQHNIDVVVDRIVIKEGIRSRL
                     FDSIEAALRIAEGYVIIDTMDDSELLFSEHYACPVCGFTVPELEPRLFSFNAPFGSCS
                     ECDGLGIKLEVDTDLVVPDASKTLREGALAPWNPISSNYYPNMLEQAMKVFGVAMDKP
                     FEDLSEEDKNLILYGSDGKEFHFHYENEFGGVRDIDIPFEGVINNIKRRYHETNSDYT
                     RTQMRLYMNELTCGTCQGYRLNDQALSVRVGGQQGPHIGEISDLSIADHLDLVSQLTL
                     SENEAIIARPILKEIKDRLTFLNNVGLNYLTLSRSAGTLSGGESQRIRLATQIGSNLS
                     GVLYILDEPSIGLHQRDNDRLIASLKKMRDLGNTLIVVEHDEDTMREADYLIDVGPGA
                     GVFGGEIVAAGTPKQVARNSKSITGQYLSGKRVIPVPEERRVGNGRFIEVIGARENNL
                     QNVTARFPLGKFIAVTGVSGSGKSTLINSILKKAIAQKLNRNSDKPGKFKTITGIEHV
                     DRLIDIDQSPIGRTPRSNPATYTGVFDDIRDLFAQTNEAKIRGYKKGRFSFNVKGGRC
                     EACSGDGIIKIEMHFLPDVYVACEVCHGTRYNSETLEVHYKEKNISQVLDMTVNDAVE
                     FFQHIPKIQRKLQTIKDVGLGYVTLGQPATTLSGGEAQRMKLASELHKRSTGKSFYIL
                     DEPTTGLHTEDIARLLKVLARFVDDGNTVLVIEHNLDVIKTADHIIDLGPEGGVGGGT
                     IIVTGTPEEVAANEASYTGHYLKGKLHHE"
     gene            35606..36667
                     /locus_tag="VU534_000119"
     CDS             35606..36667
                     /locus_tag="VU534_000119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HEU1512778.1"
                     /translation="MNKRVQAFLAKMQEKELDGIIINNLKNVYYLTGFWGSNGTVFIS
                     RDRQVLVTDSRYIIAAKQETSGFEIVADRDELAVIAGIVKDMGLTRIGFEDEISVSYY
                     HRMQAAFAGLNLLPQTQFVEGLRMIKDEAEIAAIRKACSISDQAFRDALDFIKPGKTE
                     IEIANFLDFRMRELGASGLSFDTILASGINSSKPHAHPMHKPVELGEAITMDFGCLYD
                     HYVSDMTRTIYLGHVSDEQAEIYNTVLKANQALIDQAKAGLGFRDFDKIPRDIIIEAG
                     YGDYFTHGIGHGIGLDIHEEPYFSQTSTETIKTGMALTDEPGIYIEGKYGVRIEDDIL
                     ITETGCELLTLAPKELIVI"
     gene            36799..37197
                     /gene="spx"
                     /locus_tag="VU534_000120"
     CDS             36799..37197
                     /gene="spx"
                     /locus_tag="VU534_000120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HEU1512779.1"
                     /translation="MIKIYTVSSCTSCKKAKTWLNAHQLSYKEQNLGKEGITREELLD
                     ILTKTDNGIASIVSSKNRYAKALGVDIEDLSVNEVLNLIMETPRILKSPILVDEKRLQ
                     VGYKEDDIRAFLPRSVRNVENAEARLRAAL"
     gene            37263..37832
                     /locus_tag="VU534_000121"
     CDS             37263..37832
                     /locus_tag="VU534_000121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HEU1512780.1"
                     /translation="MKKIVLVSLAFLFVLVGCGQKKETGPATKTEKDTLQSALPVIEN
                     AEKNTVVTKTLVLPKSDDGSQQTQTITYKDKTFLSLAIQQKRPVSDELKTYIDQHGVE
                     ETQKALLEAEEKDKSIIEARKLAGFKLETKLLSATELQTTTSFDFQVLDVKKASQLEH
                     LKNIGLENLLKNEPSKYISDRLANGATEQ"
     gene            37919..38185
                     /locus_tag="VU534_000122"
     CDS             37919..38185
                     /locus_tag="VU534_000122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HEU1512781.1"
                     /translation="MGFTEETVRFKLDDSNKKEISETLTDVYASLNDKGYNPINQIVG
                     YVLSGDPAYVPRYNNARNQIRKYERDEIVEELVRYYLKGQGVDL"
     gene            38189..38608
                     /gene="ruvX"
                     /locus_tag="VU534_000123"
     CDS             38189..38608
                     /gene="ruvX"
                     /locus_tag="VU534_000123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002939356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HEU1512782.1"
                     /translation="MRIMGLDVGSKTVGVAISDPLGFTAQGLEIIQINEEQGQFGFDR
                     VKELVDTYKVERFVVGLPKNMNNTSGPRVEASQAYGAKLEEFFGLPVDYQDERLTTVA
                     AERMLIEQADISRNKRKKVIDKLAAQLILQNYLDRKF"
     gene            38624..38929
                     /locus_tag="VU534_000124"
     CDS             38624..38929
                     /locus_tag="VU534_000124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HEU1512783.1"
                     /translation="MSHDHNHDHEERELITLVDEQGNETLFEILLTIDGKEEFGKNYV
                     LLVPVNAEEDEDGQVEIQAYSFIENEDGTEGELQPIPEDSEDEWNMIEEVFNSFMEE"
     gene            39188..40438
                     /locus_tag="VU534_000125"
     CDS             39188..40438
                     /locus_tag="VU534_000125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000464354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HEU1512784.1"
                     /translation="MFEVEEWLHSRIGLNFRSGLGRMQQAVDLLGNPEQSYPIIHVTG
                     TNGKGSTIAFMRELFMGHGKKVATFTSPHIVSINDRICINGQPIADADFIRLTDQVKE
                     MEKTLLQTPAQLSFFELLTLVAFLYFREQEVDLVLLEVGIGGLLDTTNVVTGEFAVIT
                     SIGLDHQETLGDSLEAIAEQKAGIFKAGKKAVIAKLPPEARLACQKKAESLAVNLYQA
                     GQDFLMLNGDFSSSLLNLSQLNIGLEGVYQQENAALALQTFLLFMRERKEAVDEQAVR
                     KALEQTHWAGRLERIRPQIYLDGAHNLPALTRLAEFIKEKEQEGYRPQILFGSLKRKD
                     YQGMLGYLTEKLPQVELKVTGFDYQGALDERDVTGYDIVSSYREFISDFEERADAQDL
                     LFVTGSLYFISEVRGYLLDREQIN"
     gene            40435..40980
                     /locus_tag="VU534_000126"
     CDS             40435..40980
                     /locus_tag="VU534_000126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001816192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipocalin/fatty acid-binding family protein"
                     /protein_id="HEU1512785.1"
                     /translation="MTPFFELVILGELLVRENFSKLVAERKFIMKLKRFTLSLASLAS
                     FSLLVACSQRAQQVQQPVAQQQVQQPAQQNTNTANAGGNQNQAAPVQNQPVAQPTDID
                     GTYTGQDDGDRITLVVTGTTGTWTELESDGDQKVKQVTLDSANQRMIIGDDVKIYTVN
                     GNQIVVDDMDRDPSDQIVLTK"
     gene            41126..42658
                     /gene="cls"
                     /locus_tag="VU534_000127"
     CDS             41126..42658
                     /gene="cls"
                     /locus_tag="VU534_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000877342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HEU1512786.1"
                     /translation="MKYRKFQLLMSKYGFSLSIMLLELCLVFGLFLYLGRMAPILWIT
                     VLILLSIITIISIVNRNTTPENKVTWLLVAFVPVFGPLLYLMFGERRLSKKEIKQLKK
                     LGSMHFQEANSQLLKEKLKESDKAAYGVIKSLLSMDTNADIYDQTASTFFPNGEAMWK
                     KMVEDLKKAEKFIFLEYYIIEEGLMWNRILDILEQKVAQGVEVKMLYDDIGCMATLTG
                     DYAHRLRQLGIEAHKFNKVIPRLTVAYNNRDHRKILIVDGQIAYTGGVNLADEYINHV
                     ERFGYWKDSGIRLDGLAVKALTRLFLTTWYINRGEISDFDQYHLENHSIPSDGLTIPY
                     GSGPKPIFRAQVGKKVYQSLINQATESVYITTPYLIIDYDLTETIKNAAMRGVDVRII
                     TPYIPDKKFIQLVTRGAYPDLLSAGVRIYEYSPGFIHSKQMLVDEDFAVVGTINLDYR
                     SLVHHYENAVLLYKTPSIREIARDFRNIFADSQEVYPHSIKTSWYQKLVKEIAQLFAP
                     IL"
     gene            42736..42879
                     /locus_tag="VU534_000128"
     CDS             42736..42879
                     /locus_tag="VU534_000128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000956126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1512787.1"
                     /translation="MLTKEEVNDMIEFKQTHLHRFREIETFVKLCKKSLKQPSQADNP
                     RTF"
     gene            42916..44454
                     /locus_tag="VU534_000129"
     CDS             42916..44454
                     /locus_tag="VU534_000129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein CinA"
                     /protein_id="HEU1512788.1"
                     /translation="MSVYGRVEEVHKENREPLEYQIEQESHHRESSRLPLVKILLWST
                     LVTGITLGVPLLLDLMSAQEVQDFYAGWALHQTGKIYSDYYGSQGLLYYLLTYVSQGG
                     FFFAIFEWLALVAGGFFLFRSADTLTEQGDQAGHLVTIFYMLVTGLAFGGGYATLLAL
                     PFLFAAFSLVAAYLSNPSHDKGFVRIGLALAGGFFFAPLSSLLFIAVVSLGLLVFNLG
                     HRRFAHGFYQFLAVALGFSLVFYPTAYYSAATGSFGDAISGIRYPIDSIRFDFTSKIL
                     ENMFFYGLLSLGLGFVVCIFLGLFQSKPFKLYVISVPASLVVILGLILLFFSQEPLHA
                     SYLMVVFPVFLLLLVTNIKSQQRGRSARRSRRETPVSLWSRFFKGNLYLLVFGFVYLL
                     SVPFLMKFVLYPVPYQERNRLADLVKEETNTEDAIYAWDDTATLYRKSERLSPSAILS
                     PLHYTATEENRNKLLNDLKEKQPKVIVVNDKVVVWSEVETLLKENYQQVKTDYSEFKV
                     YKIK"
     gene            44574..46781
                     /gene="nrdD"
                     /locus_tag="VU534_000130"
     CDS             44574..46781
                     /gene="nrdD"
                     /locus_tag="VU534_000130"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004239081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HEU1512789.1"
                     /translation="MIALEEKITILPTLFVEKRDGRRVVFDVDKIDKALHKAADKVMD
                     VTPLVEKCLNDLTERIITEIHSRFPQGIKIYEIQNIVEHELLEAKEYALAEEYITYRT
                     QRDFERSKATDINFSIHKLLNKDQTVVNENANKDSDVFNTQRDLTAGIVGKSIGLQML
                     PKHVANAHQKGDIHYHDLDYSPYTPMTNCCLIDFKGMLENGFKIGNAEVESPKSIQTA
                     TAQISQIIANVASSQYGGCSADRIDEILAPYAEKNYQKHLKDAEEWVLPEKQEDYAWK
                     KAQKDIYDAMQSLEYEINTLFTSNGQTPFTSLGFGLGTSRFEREIQKAILNIRIKGLG
                     SEHRTAIFPKLIFTLKRGLNLEEGTPNYDIKQLALECATKRMYPDVLSYDKIVDLTGS
                     FKVPMGCRSFLQGWKDENGVEVNSGRMNLGVVTVNLPRIALESEGDMNKFWEIFNERM
                     NIAEDALVYRVERTKEATPANAPILYQYGAFGHRLGKEESVDQLFKNRRATVSLGYIG
                     LYEVATVFFGNSWESNPDAKEFTLDIIHDMKRRVEEWSDQYGYHFSIYSTPSESLTDR
                     FCRLDIDKFGSIPDITDKEYYTNSFHYDVRKNPTPFEKLDFEKVYPEAGASGGFIHYC
                     EYPVLQQNPKALEAVWDYAYDRVGYLGTNTPIDRCYKCDFEGDFEPTERGFACPNCGN
                     SDPKTVDVVKRTCGYLGNPQARPMVNGRHKEIAARVKHMNGSTIKIAGHQVTN"
     gene            46793..46933
                     /locus_tag="VU534_000131"
     CDS             46793..46933
                     /locus_tag="VU534_000131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1512790.1"
                     /translation="MGKYQLDDKGRAQVTRYHEKHSKGGAGKKERLLSFREQFLNKNK
                     KK"
     gene            46977..47483
                     /locus_tag="VU534_000132"
     CDS             46977..47483
                     /locus_tag="VU534_000132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000423398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU1512791.1"
                     /translation="MELRRPRLADKKAVLDMMTEFEKFQSPHDGGFWDTENFVYEDWL
                     ESNQEQEMGINLPEGWVSAIQLVAFSEKGQAVGFLNLRLRLSNFLLEEGGHIGYSIRP
                     SERGKGYAKETLRQGLQVAKEKNIKKALVTCSVNNPASRAVILANGGIFEDARNGVER
                     YWIEVANE"
     gene            47476..48066
                     /gene="nrdG"
                     /locus_tag="VU534_000133"
     CDS             47476..48066
                     /gene="nrdG"
                     /locus_tag="VU534_000133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001064213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HEU1512792.1"
                     /translation="MNNPKPQEWKSEELSQGRIIDYKAFNFVDGEGVRNSLYVSGCMF
                     HCEGCYNVATWSFNAGIPYTAELEEQIMADLAQPYVQGLTLLGGEPFLNTGILLPLVK
                     RIRKELPDKDIWSWTGYTWEEMMLETPDKLEFLSLIDILVDGRYDRTKRNLMLQFRGS
                     SNQRIIDVQKSLKSGQVVIWDKLNDGKESYEQVKRE"
     gene            48063..48680
                     /locus_tag="VU534_000134"
     CDS             48063..48680
                     /locus_tag="VU534_000134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribulokinase"
                     /protein_id="HEU1512793.1"
                     /translation="MKKKDLVDQLVSEIETGKVRTLGIYGHGASGKSTFAQELYQALD
                     STTVNLLETDPYITSGRHLVVPKDAPNQKVTASLPVAHELESLQRDILALQAGMDVLT
                     IEEPWKASEVLSGAKPILIVEGMSVGFLPKELFEKTICFYTDEETELKRRLARDTTVR
                     NRDASFILASHQMRREQYLRYYKETESKADILVDQSEDKFDVKRT"
     gene            48947..49255
                     /gene="rpsJ"
                     /locus_tag="VU534_000135"
     CDS             48947..49255
                     /gene="rpsJ"
                     /locus_tag="VU534_000135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HEU1512794.1"
                     /translation="MANKKIRIRLKAYEHRTLDTAAAKIVESATRTGAQVAGPIPLPT
                     ERSLYTIIRATHKYKDSREQFEMRTHKRLIDIVNPTQKTVDALMKLDLPSGVNVEIKL
                     "
     gene            49472..50098
                     /gene="rplC"
                     /locus_tag="VU534_000136"
     CDS             49472..50098
                     /gene="rplC"
                     /locus_tag="VU534_000136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HEU1512795.1"
                     /translation="MTKGILGKKVGMTQIFTEAGELIPVTVIEATPNVVLQVKTVETD
                     GYNAIQVGFDDKREVLSNKPAKGHVAKANTAPKRFIREFKNVEGLEVGAEITVETFAA
                     GDVVDVTGTSKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVAPNRVFKGKNLAG
                     RMGGDRVTIQNLEVVQVVPEKNVILIKGNVPGAKKSLITIKSAVKAGK"
     gene            50123..50746
                     /gene="rplD"
                     /locus_tag="VU534_000137"
     CDS             50123..50746
                     /gene="rplD"
                     /locus_tag="VU534_000137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HEU1512796.1"
                     /translation="MANVTLFDQTGKEAGQVVLSDAVFGIEPNESVVFDVIISQRASL
                     RQGTHAVKNRSAVSGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYGYKLP
                     QKVRRLALKSVYSEKVAENKFVAVDALSFTAPKTAEFAKVLAALSIDSKVLVILEEGN
                     EFAALSARNLPNVKVATATTASVLDIANSDKLLVTQAAISKIEEVLA"
     gene            50746..51042
                     /locus_tag="VU534_000138"
     CDS             50746..51042
                     /locus_tag="VU534_000138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007518994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HEU1512797.1"
                     /translation="MNLYDVIKKPVITESSMAQLEAGKYVFEVDTRAHKLLIKQAVEA
                     AFEGVKVANVNTINVKPKAKRVGRYTGFTNKTKKAIITLTADSKAIELFAAEAE"
     gene            51060..51893
                     /gene="rplB"
                     /locus_tag="VU534_000139"
     CDS             51060..51893
                     /gene="rplB"
                     /locus_tag="VU534_000139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019790357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HEU1512798.1"
                     /translation="MGIRVYKPTTNGRRNMTSLDFAEITTSTPEKSLLVALKSKAGRN
                     NNGRITVRHQGGGHKRFYRLVDFKRNKDNVEAVVKTIEYDPNRSANIALVHYTDGVKA
                     YIIAPKGLEVGQRIVSGPEADIKVGNALPLANIPVGTLIHNIELKPGRGGELVRAAGA
                     SAQVLGSEGKYVLVRLQSGEVRMILGTCRATVGVVGNEQHGLVNLGKAGRSRWKGIRP
                     TVRGSVMNPNDHPHGGGEGKAPVGRKAPSTPWGKPALGLKTRNKKAKSDKLIVRRRNE
                     K"
     gene            51997..52278
                     /gene="rpsS"
                     /locus_tag="VU534_000140"
     CDS             51997..52278
                     /gene="rpsS"
                     /locus_tag="VU534_000140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HEU1512799.1"
                     /translation="MGRSLKKGPFVDEHLMKKVEAQANDEKKKVIKTWSRRSTIFPSF
                     IGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYKGHAADDKKTRRK"
     gene            52290..52634
                     /gene="rplV"
                     /locus_tag="VU534_000141"
     CDS             52290..52634
                     /gene="rplV"
                     /locus_tag="VU534_000141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HEU1512800.1"
                     /translation="MAEITSAKAMARTVRVSPRKSRLVLDNIRGKSVADAIAILTFTP
                     NKAAEIILKVLNSAVANAENNFGLDKANLVVSEAFANEGPTMKRFRPRAKGSASPINK
                     RTAHITVAVAEK"
     gene            52647..53300
                     /gene="rpsC"
                     /locus_tag="VU534_000142"
     CDS             52647..53300
                     /gene="rpsC"
                     /locus_tag="VU534_000142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HEU1512801.1"
                     /translation="MGQKVHPIGMRVGIIRDWDAKWYAEKEYADYLHEDLAIRKFVQK
                     ELADAAVSTIEIERAVNKVNVSLHTAKPGMVIGKGGANVDALRAKLNKLTGKQVHINI
                     IEIKQPDLDAHLVGEGIARQLEQRVAFRRAQKQAIQRAMRAGAKGIKTQVSGRLNGAD
                     IARAEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEVLPARKNTKGGK"
     gene            53304..53717
                     /gene="rplP"
                     /locus_tag="VU534_000143"
     CDS             53304..53717
                     /gene="rplP"
                     /locus_tag="VU534_000143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003029477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HEU1512802.1"
                     /translation="MLVPKRVKHRREFRGKMRGEAKGGKEVAFGEYGLQATTSHWITN
                     RQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKV
                     MFEIAGVSEEIAREALRLASHKLPVKCKFVKREAE"
     gene            53727..53933
                     /locus_tag="VU534_000144"
     CDS             53727..53933
                     /locus_tag="VU534_000144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006739716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HEU1512803.1"
                     /translation="MKLNEVKEFVKELRGLSQEELAKRENELKKELFELRFQAATGQL
                     EQTARLKEVKKQIARIKTVQSEAK"
     gene            53958..54218
                     /gene="rpsQ"
                     /locus_tag="VU534_000145"
     CDS             53958..54218
                     /gene="rpsQ"
                     /locus_tag="VU534_000145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HEU1512804.1"
                     /translation="MERNNRKVLVGRVVSDKMDKTITVVVETKRNHPVYGKRINYSKK
                     YKAHDENNVAKEGDIVRIMETRPLSATKRFRLVEVVEEAVII"
     gene            54244..54612
                     /gene="rplN"
                     /locus_tag="VU534_000146"
     CDS             54244..54612
                     /gene="rplN"
                     /locus_tag="VU534_000146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012727667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HEU1512805.1"
                     /translation="MIQTETRLKVADNSGAREILTIKVLGGSGRKFANIGDVIVASVK
                     QATPGGAVKKGDVVKAVIVRTKSGARRADGSYIKFDENAAVIIREDKTPRGTRIFGPV
                     ARELREGGFMKIVSLAPEVL"
     gene            54690..54995
                     /gene="rplX"
                     /locus_tag="VU534_000147"
     CDS             54690..54995
                     /gene="rplX"
                     /locus_tag="VU534_000147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011921687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HEU1512806.1"
                     /translation="MFVKKGDKVRVIAGKDKGTEAVVLTALPKVNKVIVEGVNIVKKH
                     QRPTNELPQGGIIEKEAAIHVSNVQVLDKNGVAGRVGYKFVDGKKVRYNKKSGEVLD"
     gene            55019..55561
                     /gene="rplE"
                     /locus_tag="VU534_000148"
     CDS             55019..55561
                     /gene="rplE"
                     /locus_tag="VU534_000148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HEU1512807.1"
                     /translation="MANRLKEKYLNEVVPALTEQFNYSSVMAVPKVDKIVLNMGVGEA
                     VSNAKSLEKAAEELALISGQKPLITKAKKSIAGFRLREGVAIGAKVTLRGERMYEFLD
                     KLVSVSLPRVRDFHGVPTKSFDGRGNYTLGVKEQLIFPEINFDDVDKTRGLDIVIVTT
                     ANTDEESRALLTGLGMPFAK"
     gene            55579..55848
                     /gene="rpsN"
                     /locus_tag="VU534_000149"
     CDS             55579..55848
                     /gene="rpsN"
                     /locus_tag="VU534_000149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HEU1512808.1"
                     /translation="MAKKSMVAREAKRQKIVDRYAEKRAALKAAGDYEGLSKLPRNAS
                     PTRLHNRCRVTGRPHSVYRKFGLSRIAFRELAHKGQIPGVTKASW"
     gene            56133..56531
                     /gene="rpsH"
                     /locus_tag="VU534_000150"
     CDS             56133..56531
                     /gene="rpsH"
                     /locus_tag="VU534_000150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009754342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HEU1512809.1"
                     /translation="MVMTDPIADFLTRIRNANQAKHEVLEVPASNIKKGIAEILKREG
                     FVKNVEIIEDDKQGVIRVFLKYGPNGEKVITNLKRVSKPGLRVYKKREDLPKVLNGLG
                     IAILSTSEGLLTDKEARQKNVGGEVIAYVW"
     gene            56723..57259
                     /gene="rplF"
                     /locus_tag="VU534_000151"
     CDS             56723..57259
                     /gene="rplF"
                     /locus_tag="VU534_000151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HEU1512810.1"
                     /translation="MSRIGNKVIVLPAGVELANNDNVVTVKGSKGELTREFSKDIEIR
                     VEGTEITLHRPNDSKEMKTIHGTTRALLNNMVVGVSEGFKKELEMRGVGYRAQLQGSK
                     LVLAVGKSHPDEVEAPEGITFELPNPTTIVVSGISKEVVGQTAAYVRSLRSPEPYKGK
                     GIRYVGEFVRRKEGKTGK"
     gene            57343..57699
                     /gene="rplR"
                     /locus_tag="VU534_000152"
     CDS             57343..57699
                     /gene="rplR"
                     /locus_tag="VU534_000152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HEU1512811.1"
                     /translation="MISKPDKNKLRQKRHRRVRGKLSGTADRPRLNVFRSNTGIYAQV
                     IDDVAGVTLASASTLDKEVSKGTKTEQAVAVGKLVAERANAKGISEVVFDRGGYLYHG
                     RVKALADAARENGLKF"
     gene            57717..58211
                     /gene="rpsE"
                     /locus_tag="VU534_000153"
     CDS             57717..58211
                     /gene="rpsE"
                     /locus_tag="VU534_000153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HEU1512812.1"
                     /translation="MAFKDNAVELEERVVAVNRVTKVVKGGRRLRFAALVVVGDHNGR
                     VGFGTGKAQEVPEAIRKAVDDAKKNLIEVPMVGTTIPHEVLSEFGGAKVLLKPAVEGS
                     GVAAGGAVRAVVELAGVADITSKSLGSNTPINIVRATVEGLKQLKRAEEIAALRGISV
                     SDLA"
     gene            58183..58407
                     /gene="rpmD"
                     /locus_tag="VU534_000154"
     CDS             58183..58407
                     /gene="rpmD"
                     /locus_tag="VU534_000154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012386624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HEU1512813.1"
                     /translation="MVFQFLIWHKKGDKMAQIKITLTKSPIGRIPSQRKTVVALGLGK
                     LNSSVIKEDNAAIRGMITAVSHLVTVEEVN"
     gene            58552..58992
                     /gene="rplO"
                     /locus_tag="VU534_000155"
     CDS             58552..58992
                     /gene="rplO"
                     /locus_tag="VU534_000155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004225266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HEU1512814.1"
                     /translation="MKLHELKPAEGSRKVRNRVGRGTSSGNGKTSGRGQKGQKARSGG
                     GVRLGFEGGQTPLFRRLPKRGFTNINAKEYAIVNLDQLNVFEDGAEVTPVVLIEAGIV
                     KAEKSGIKILGNGELTKKLTVKAAKFSKSAEEAITAKGGSVEVI"
     gene            59005..60315
                     /gene="secY"
                     /locus_tag="VU534_000156"
     CDS             59005..60315
                     /gene="secY"
                     /locus_tag="VU534_000156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HEU1512815.1"
                     /translation="MFFKLLREALKVKQVRSKILFTIFIVLVFRIGTSITVPGVNANS
                     LNALSGLSFLNMLSLVSGNALKNFSIFALGVSPYITASIVVQLLQMDILPKFVEWGKQ
                     GEVGRRKLNQATRYIALVLAFVQSIGITAGFNTLAGAQLIKTALTPQVFLTIGIILTA
                     GSMIVTWLGEQITDKGYGNGVSMIIFAGIVSSIPEMIQGIYVDYFVNVPSSRITSSII
                     FVIILIITVLLIIYFTTYVQQAEYKIPIQYTKVAQGAPSSSYLPLKVNPAGVIPVIFA
                     SSITAAPAAILQFLSATGHDWAWVRVAQEMLATTSPTGIAMYALLIILFTFFYTFVQI
                     NPEKAAESLQKSGAYIHGVRPGKGTEEYMSKLLRRLATVGSLFLGVISILPIAAKDVF
                     GLSDVVAFGGTSLLIIISTGIEGIKQLEGYLLKRKYVGFMDRTE"
     gene            60466..61104
                     /locus_tag="VU534_000157"
     CDS             60466..61104
                     /locus_tag="VU534_000157"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HEU1512816.1"
                     /translation="MNLLIMGLPGAGKGTQAAKIVEQFHVAHISTGDMFRAAMANQTE
                     MGVLAKSYIDKGELVPDEVTNGIVKERLSQDDIKETGFLLDGYPRTIEQAHALDKTLA
                     ELGIELEGVINIEVNPDSLLERLSGRIIHRVTGETFHKVFNPPVDYKEEDYYQREDDK
                     PETVKRRLDVNIAQGEPIIAHYRAKGLVHDIEGNQDINDVFSDIEKVLTNLK"
     gene            61221..61439
                     /gene="infA"
                     /locus_tag="VU534_000158"
     CDS             61221..61439
                     /gene="infA"
                     /locus_tag="VU534_000158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HEU1512817.1"
                     /translation="MAKDDVIEVEGKVVDTMPNAMFTVELENGHQILATVSGKIRKNY
                     IRILAGDRVTVEMSPYDLTRGRITYRFK"
     gene            61464..61580
                     /gene="rpmJ"
                     /locus_tag="VU534_000159"
     CDS             61464..61580
                     /gene="rpmJ"
                     /locus_tag="VU534_000159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HEU1512818.1"
                     /translation="MKVRPSVKPICEYCKVIRRNGRVMVICPANPKHKQRQG"
     gene            61598..61963
                     /gene="rpsM"
                     /locus_tag="VU534_000160"
     CDS             61598..61963
                     /gene="rpsM"
                     /locus_tag="VU534_000160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HEU1512819.1"
                     /translation="MARIAGVDIPNDKRVVISLTYVYGIGLATSKKILAAAGISEDVR
                     VRDLTSDQEDAIRREVDAIKVEGDLRREVNLNIKRLMEIGSYRGIRHRRGLPVRGQNT
                     KNNARTRKGKAVAIAGKKK"
     gene            61981..62364
                     /gene="rpsK"
                     /locus_tag="VU534_000161"
     CDS             61981..62364
                     /gene="rpsK"
                     /locus_tag="VU534_000161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HEU1512820.1"
                     /translation="MAKPTRKRRVKKNIESGIAHIHATFNNTIVMITDVHGNAIAWSS
                     AGALGFKGSRKSTPFAAQMASEAAAKSAQEHGLKSVEVTVKGPGSGRESAIRALAAAG
                     LEVTAIRDVTPVPHNGARPPKRRRV"
     gene            62407..63342
                     /locus_tag="VU534_000162"
     CDS             62407..63342
                     /locus_tag="VU534_000162"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HEU1512821.1"
                     /translation="MIEFEKPNITKIDENKDYGKFVIEPLERGYGTTLGNSLRRVLLA
                     SLPGAAVTSINIDGVLHEFDTVPGVREDVMQIILNIKGIAVKSYVEDEKIIELDVEGP
                     AEVTAGDILTDSDIEIVNPDHYLFTIGEGSSLKATMTVNSGRGYVPADENKKDNAPVG
                     TLAVDSIYTPVTKVNYQVEPARVGSNDGFDKLTLEILTNGTIIPEDALGLSARILTEH
                     LDLFTNLTEIAKSTEVMKEADTESDDRILDRTIEELDLSVRSYNCLKRAGINTVHDLT
                     EKSEAEMMKVRNLGRKSLEEVKLKLIDLGLGLKDK"
     gene            63354..63740
                     /gene="rplQ"
                     /locus_tag="VU534_000163"
     CDS             63354..63740
                     /gene="rplQ"
                     /locus_tag="VU534_000163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002887523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HEU1512822.1"
                     /translation="MAYRKLGRTSSQRKAMLRDLTTDLLINESIVTTEARAKEIRKTV
                     EKMITLGKRGDLHARRQAAAFVRNEIASENYDEATDKYTSTTALQKLFSEIAPRYAER
                     NGGYTRILKTESRRGDAAPMAIIELV"
     gene            64005..64271
                     /locus_tag="VU534_000164"
     CDS             64005..64271
                     /locus_tag="VU534_000164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002905356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HEU1512823.1"
                     /translation="MKAIITVVGKDKSGIVAGVSGKIAELGLNIDDISQTVLDEYFTM
                     MAVVSSDEKQDFTYLRNEFEAFGQTLNVKINIQSAAIFEAMYNI"
     gene            64281..65618
                     /locus_tag="VU534_000165"
     CDS             64281..65618
                     /locus_tag="VU534_000165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PFL family protein"
                     /protein_id="HEU1512824.1"
                     /translation="MDIRQVTETIAMIEEQNFDIRTITMGISLLDCIDPDINRAAEKI
                     YQKITTKAANLVAVGDEIAAELGIPIVNKRVSVTPISLIGAATDATDYVVLAKALDKA
                     AKEIGVDFIGGFSALVQKGYQKGDEILINSIPRALAETDKVCSSVNIGSTKSGINMTA
                     VADMGRIIKETANLSDMGVAKLVVFANAVEDNPFMAGAFHGVGEADVIINVGVSGPGV
                     VKRALEKVRGQSFDVVAETVKKTAFKITRIGQLVGQMASERLGVEFGIVDLSLAPTPA
                     VGDSVARVLEEMGLETVGTHGTTAALALLNDQVKKGGVMACNQVGGLSGAFIPVSEDE
                     GMIAAVQNGSLNLEKLEAMTAICSVGLDMIAIPEDTPAETIAAMIADEAAIGVINMKT
                     TAVRIIPKGKEGDMIEFGGLLGTAPVMKVNGASSVDFISRGGQIPAPIHSFKN"
     gene            65862..66554
                     /locus_tag="VU534_000166"
     CDS             65862..66554
                     /locus_tag="VU534_000166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEU1512825.1"
                     /translation="MVKVRLYLVRHGKTMFNTIGRAQGWSDTPLTAEGERGIQELGIG
                     LRESDLQFERAYSSDSGRTIQTMGIILEELGLQGEIPYRMDKRIREWCFGSFDGAYDG
                     DLFMGIIPRIFNVDHVHQLSYAELAEGLVEVDTAGWAEGWEKLSGRIKEGFEMIAKEM
                     EDQGGGNALVVSHGMTIGTIVYLINGMHPHGLDNGSVTILEYEDGQFRVEVVGDRSYR
                     ELGREKMEEGSI"
     gene            complement(66657..68302)
                     /locus_tag="VU534_000167"
                     /pseudo
     CDS             complement(66657..68302)
                     /locus_tag="VU534_000167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520796.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
     gene            complement(68292..69383)
                     /locus_tag="VU534_000168"
     CDS             complement(68292..69383)
                     /locus_tag="VU534_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001289361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU1512826.1"
                     /translation="MSEIKIINAKKIYHDVPVIENLNITIPKGSLFTLLGASGCGKTT
                     LLRMIAGFNSIEGGEFYFDDTKINNMEPSKRNIGMVFQNYAIFPHLTVRDNVAFGLMQ
                     KKVPKEELIQQTNKYLELMQIAQYADRKPDKLSGGQQQRVTLACALAVNPSVLLMDEP
                     LSNLEAKLRLDMRQAIREIQHEVGITTVYVTHDQEEAMAISDQIAVMKDGVIQQIGRP
                     KELYHKPANEFVATFIGRTNIIPANLEKRSDGAYIVFSDGYALRMPALDQVEEQAIHV
                     SIRPEEFIKDESGDIEGTIRDSVYLGLNTDYFIETGFASKIQVSEESTFEEDLQKGNR
                     IRLRINTQKLNIFSADGSQNLIKGVNHGT"
     gene            complement(69396..70412)
                     /locus_tag="VU534_000169"
     CDS             complement(69396..70412)
                     /locus_tag="VU534_000169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEU1512827.1"
                     /translation="MKKKWMYYAACSSNESADDSSSDKGDGGSLVVYSPNSEGLIGAT
                     IPAFEEKYGIKVELIQAGTGELFKKLESEKEVPVADVIFGGSYTQYTTHGELFENYTS
                     KENDNVIKEYQNTTGYSTPYTLDGSVLIVNPDLTKGMNIEGYNDLFKPELKGKIATAD
                     PANSSSAFAQLTNMLQAQGGYKDDKAWSYVKDLFTLIDGKIGSSSSSVYKVVADGEMA
                     VGLSYEDPAVKLLNDGANIKVVYPKEGTVFLPASAAIVKKSKNMENAKKFIDFIISQE
                     VQDTLGTTTTNRPVRKNAKTSENMKPIDKIKTLTEDYDYVIKNKSDIVKKYNEVFTDI
                     QSKQ"
     gene            complement(70999..71775)
                     /locus_tag="VU534_000170"
     CDS             complement(70999..71775)
                     /locus_tag="VU534_000170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000406168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl-radical enzyme activating protein"
                     /protein_id="HEU1512828.1"
                     /translation="MEISKGIIFNIQHFSIHDGPGIRTTVFLKGCPLRCPWCSNPESQ
                     RMKPEKMKDAQREKFTLVGEEKTVEEIITEVLKDKEFYEESGGGLTLSGGEIFAQFEF
                     AKAILKSAKEHHIHTAIETTAFVDHEKFIDLIQYVDFIYTDLKHYNSIKHKKVTGVFN
                     QMIIKNIHYAFSQNKTIVLRIPVIPNFNNSLEDAEKFATLFNSLNIDQVQLLPFHQFG
                     ENKYRLLNRKYEMDGINALHPEDLIDYQKVFLNHHINCYF"
     gene            71897..72643
                     /locus_tag="VU534_000171"
     CDS             71897..72643
                     /locus_tag="VU534_000171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000824973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEU1512829.1"
                     /translation="MKRLEQIIKLVSEYEKIDVNTLSEKLNVSKVTIRKDLDKLESKG
                     LLHREHGYAVLNSGDDLNVRLSINYETKRKIVQEAVKLVSDNETIMIESGSTCALLAE
                     EICKQKRNVTIVTNSFFIANFVRAYDSCRVIVLGGEFQKDSQVTVGPLLKEMIQTFHV
                     CQAFVGTDGYDKEMGFTGKDLMRSEVVQYISAVSDKVIVLTDSSKFDKRGTVRRFALS
                     QVYEVITDEKLSKQNIATLENAGIMVKVVS"
     gene            72656..73636
                     /locus_tag="VU534_000172"
     CDS             72656..73636
                     /locus_tag="VU534_000172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001070834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding transcriptional regulator"
                     /protein_id="HEU1512830.1"
                     /translation="MNQDRNKLLSKIAYLYYIENLNQSQIAAKLGIYRTSISRMLTEA
                     RNVGIVKIEIENFDTNMFKLENYVKEKYSLESLEIIPNEFDDTPTILSERISQVAAGV
                     LRNLIDDNMKIGFSWGKSLSNLVDLIHSKSVRNVHFYPLAGGPSHIHAKYHVNTLIYE
                     MSRKFHGECTFMNATIVQENKLLADGILQSRYFENLKNSWKDLDIAVVGIGDFSNKGK
                     HQWLDMLTEDDFKELTKVKTVGEICCRFFDSKGKEVYENLQERTIAISLEDLKNIPQS
                     LAVAYGDTKVSSILSVLRANLVNHLITDKNTILKVLEEDGDLTFREILGE"
     gene            73831..74151
                     /locus_tag="VU534_000173"
     CDS             73831..74151
                     /locus_tag="VU534_000173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEU1512831.1"
                     /translation="MEMIVPDQIIMGLILYAGDAKQHIYKALDYIKNGTCERCEEEIQ
                     LADAALLEAHNLQTKFLAQEASGTKTEITALFVHSQDHLMTSMTEINLIKEIISLRKE
                     LHKK"
     gene            74197..74505
                     /locus_tag="VU534_000174"
     CDS             74197..74505
                     /locus_tag="VU534_000174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000238716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEU1512832.1"
                     /translation="MVKIGLFCAAGFSTGMLVNNMKIAAQSSGVEAEIEAFSQSKLAD
                     YAPNIDVALLGPQVAYTLDKSKEICDKCDVPIAVIPMMDYGMLDGKKVLDLALSLISG
                     "
     gene            74522..75820
                     /locus_tag="VU534_000175"
     CDS             74522..75820
                     /locus_tag="VU534_000175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000041357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEU1512833.1"
                     /translation="MSKMDVQKIIAPMMKFVNMRGIIALKDGMLAILPLTVVGSLFLI
                     MGQLPFEGLNKSIASVFGANWTEPFMQVYSGTFAIMGLISCFSIAYSYAKNSGVEALP
                     AGVLSVSAFFILLRSSYIPKQGEAIGDAISKVWFGGQGIIGAIIIGLVVGSIYTFFIK
                     RKIVIKMPEQVPQAIAKQFEAMIPAFVIFLSSMIVYILAKSLTNGGTFIEMIYSAIQV
                     PLQGLTGSLYGAIGIAFFISFLWWFGVHGQSVVNGVVTALLLSNLDANKAMLASANLS
                     LENGAHIVTQQFLDSFLILSGSGITFGLVVAMLFAAKSKQYQALGKVAAFPAIFNVNE
                     PVVFGFPIVMNPVMFVPFILVPVLAAVIVYGAIATGFMQPFSGVTLPWSTPAILSGFL
                     VGGWQGVITQLVILAMSTLVYFPFFKVQDRLAYQNEIKQS"
     gene            75971..78409
                     /locus_tag="VU534_000176"
     CDS             75971..78409
                     /locus_tag="VU534_000176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl radical protein"
                     /protein_id="HEU1512834.1"
                     /translation="MVNTEVARTTIKTEYFGSLTERMNKYREDVLNKKPYIDAERAVL
                     ATRAYERYKEQPNVLKRAYMLKEILENMTIYIEEESMIAGNQASSNKDAPIFPEYTLE
                     FVLNELDLFEKRDGDVFYITEETKEQLRSIAPFWENNNLRARAGALLPEEVSVYMETG
                     FFGMEGKMNSGDAHLAVNYQKLLQFGLRGFEERARKAKVALDLTDPASIDKYHFYDSI
                     FIVIDAIKVYAKRFVALAKSLAENANPKRKKELLEIADICSRVPYEPATTFAEAIQSV
                     WFIQCILQIESNGHSLSYGRFDQYMYPYMKADLESGKETEDSIVERLTNLWIKTITIN
                     KVRSQSHTFSSAGSPLYQNVTIGGQTRDKKDAVNPLSYLVLKSVAQTHLPQPNLTVRY
                     HAGLDARFMNECIEVMKLGFGMPAFNNDEIIIPSFIAKGVLEDDAYDYSAIGCVETAV
                     PGKWGYRCTGMSYMNFPKVLLITMNDGIDPASGKRFAPSFGRFKDMKNFSELENAWDK
                     TLRYLTRMSVIVENSIDLSLEREVPDILCSALTDDCIGRGKHLKEGGAVYDYISGLQV
                     GIANLSDSLAAIKKLVFEEERISPSQLWHALETDYAGEEGKVIQEMLIHDAPKYGNDD
                     DYADKLVTAAYDIYVDEIAKYPNTRYGRGPIGGIRYSGTSSISANVGQGRGTLATPDG
                     RNAGTPLAEGCSPSHNMDQHGPTSVLKSVSKLPTDEIVGGVLLNQKVNPQTLAKEEDK
                     LKLIALLRTFFNRLHGYHIQYNVVSRETLIDAQKHPEKHRDLIVRVAGYSAFFNVLSK
                     ATQDDIIGRTEHTL"
     gene            78428..79096
                     /locus_tag="VU534_000177"
     CDS             78428..79096
                     /locus_tag="VU534_000177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000395441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HEU1512835.1"
                     /translation="MEFMLDTLNLDEIKKWSEILPLAGVTSNPTIAKREGSINFFERI
                     KDVRELIGSTPSIHVQVISQDFEGILKDAHKIRRQAGDDIFIKVPVTPAGLRAIKALK
                     KEGYHITATAIYTVIQGLLAIEAGADYLAPYYNRMENLNIDSNSVIRQLALAIDRQNS
                     PSKILAASFKNVAQVNNALAAGAHAVTAGADVFESAFAMPSIQKAVDDFSDDWFVIQN
                     SRSI"
     gene            79114..80202
                     /locus_tag="VU534_000178"
     CDS             79114..80202
                     /locus_tag="VU534_000178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol dehydrogenase"
                     /protein_id="HEU1512836.1"
                     /translation="MRIFASPSRYIQGENALFENAKSILDLGNCPILLCDQLVYDIVG
                     KRFEDYLHRYGFHIVLALFNGEASDNEINRVVALAEKENCDSIIGLGGGKTIDSAKAI
                     ADLIEKPVIIAPTIASTDAPVSALSVIYTDEGAFDHYLFYSKNPDLVLVDTKVISQAP
                     KRLLASGIADGLATWVEARAVMQANGKTMLGQQQTLAGVAIAKKCEETLFADGLQAMA
                     ACEAKVVTPALENIVEANTLLSGLGFESGGLAAAHAIHNGFTALTGDIHHLTHGEKVA
                     YGTLVQLLLENRPKEELDKYIEFYKKIGMPTTLKEMHLDQVGYDDLIKVGKQATMEGE
                     TIHQMPFKISPSDVAQAIIAVDAYVNSK"
     gene            80657..83158
                     /locus_tag="VU534_000179"
     CDS             80657..83158
                     /locus_tag="VU534_000179"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014639013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HEU1512837.1"
                     /translation="MSFYNHKEIEPKWQGYWAEHHTFKTGTDTSKPKFYALDMFPYPS
                     GAGLHVGHPEGYTATDILSRYKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTA
                     ENIANFKRQINALGFSYDWDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVE
                     ELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLNDLDELDWSESIKD
                     MQRNWIGKSTGANVTFKVKGTDKEFTVFTTRPDTLFGATFTVLAPEHELVDAITSSEQ
                     AEAVADYKHQASLKSDLARTDLAKEKTGVWTGAYAINPVNGKEMPIWIADYVLASYGT
                     GAVMAVPAHDQRDWEFAKQFDLPIVEVLEGGNVEEAAYTEDGLHVNSDFLDGLNKEDA
                     IAKIVAWLEEKGCGQEKVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPETELPLV
                     LPVTKDIRPSGTGESPLANLTDWLEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPH
                     NTEKLADEDLLKQWLPVDIYVGGAEHAVLHLLYARFWHKFLYDLGVVPTKEPFQKLFN
                     QGMILGTSYRDHRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDV
                     VEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITSKEILAENNGALD
                     KVYNETVKAVTEQIESLKFNTAIAQLMVFVNAANKEDKLYVDYAKGFIQLIAPFAPHL
                     AEELWQTVAETGESISYVAWPTWDESKLVEDEIEIVVQIKGKVRAKLMVAKDLSREEL
                     QEIALADEKVKAEIDGKEIVKVIAVPNKLVNIVVK"
     gene            83353..84048
                     /locus_tag="VU534_000180"
     CDS             83353..84048
                     /locus_tag="VU534_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001144916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU1512838.1"
                     /translation="MPVNEYGQMIGESMEAYTPGELPSFDFLEGRYARIEALSVEKHA
                     EDLLAVYGPDTPREMWTYLFQESVADMEELVSLLNQMLARKDRFYYAIIDKATGKALG
                     TFSLMRIDQNNRVIEVGAVTFSPELRGTRIGTEAQYLLACYVFEELNYRRYEWKCDAL
                     NLPSRRAAERLGFIYEGTFRQAVVYKGRTRDTDWLSMIDKDWPQVKARLEIWLRPENF
                     DKNGRQHKSLREL"
     gene            84060..84476
                     /locus_tag="VU534_000181"
     CDS             84060..84476
                     /locus_tag="VU534_000181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU1512839.1"
                     /translation="MITIKKQEIVKLEDVLHLYQAVGWTNYTHQTEMLEQALSHSLVI
                     YLALDGDAVVGLIRLVGDGFSSVFVQDLIVLPSYQRQGIGSSLMKEALGNFKEAYQVQ
                     LATEETEKNVGFYRSMGFEILSTYDCTGMIWINREK"
BASE COUNT        25958 a        14984 c        18316 g        25367 t
ORIGIN      
        1 aatagtccat gctgtggttg gattcttttc agcctacttg tactcttcga aactctcttc
       61 aaaccacgtc agcttcactt tgccgtaggt atggttactg acttcgtcag ttctatccac
      121 aacctcaaaa cggtgttttg agctgacttc gtcagttcta tccacaacct caaaacagtg
      181 ttttgagctg acttcatcag ttctatctgc aacctcaaaa cagtgttttg agcaacctgc
      241 ggctagtttc ctagtttgct ctttgatttt cattgagtat tattaagaca atatgagaag
      301 aaagatgaaa gaaaaaggat tttaggaggg ggcgcaggca gccatgccaa cggctcttgg
      361 ctatgtcagt atcggcctgg cctgtggaat tatcggtgcg ccctatgtga cacctgttga
      421 gatgggcttg atgagtctct ttgtttatgc tgggagtgcc cagtttgcca tgttggcact
      481 gattgtggtt caagctcctg tggcagctat tgctatgacg gtttttctaa tcaacttgcg
      541 tctctttttg ttgagtttat acgcatcgac ttatttccgt cataccagtc tttggtacaa
      601 tatcggtatg tctagtatct tgacagatga gacctatggc gttttgatgg gtgaattggc
      661 ccatacagac aaggtaaatc ctatgtggat gcacggaaac aatcttaaca gctatgtggc
      721 ttggtttgtg gggacagtag tcggaacggc tctgggtggc ctgctaccaa atccagaaat
      781 ctttggcttg gattttgccc tggttgggat gtttattggt atttttgctt cgcaatttca
      841 gattatgcaa agacggattc ctgtccgcaa tctgctcatt atcctagcag ttgttgcggt
      901 gtccttcttt ttgctcttga cagtgatgtc tcagtcacta gctgttctgt ttgcgacgct
      961 acttggttgt agcatggggg tggttttaga tggtcagtaa gtatctttta ttagcagtta
     1021 ttttctctgg cttggtgact tggattcccc gtatgattcc cttcatcttg gtcaagtata
     1081 agggcctgcc tgcgattgtt gagcgttttt tgaagttttt gcctgtttcc attatctttg
     1141 ccctgattct ttcaagcgta gtgacaggta aggttggcag tcttcctcaa atcaaatgac
     1201 tggacttctt agccgtcttt ccaacagctt gggtagcctt tcgctaccgc aatctagtcg
     1261 gaacagttct ctttggagtg gtcttgattg ccatcttgcg tttggtcttt taaattaccc
     1321 ataaaaaaaa cttatcacag agatagatat catataatgg cgtaaatgct ctttttctgt
     1381 taagattata aggtattcta ttttggagga aatgacatga aaaaaatcgt taaatactca
     1441 tctcttgcag cccttgctct tgttgctgca ggtgtgcttg cggcttgctc agggggtgct
     1501 aagaaagaag gagaagcagc tagcaagaaa gaaatcatcg ttgcaaccaa tggatcacca
     1561 aagccattta tctatgaaga aaatggcgaa ttgactggtt acgagattga agtcgttcgc
     1621 gctatcttta aagattctga caaatatgat gtcaagtttg aaaagacaga atggtcaggt
     1681 gtctttgctg gtcttgacgc tgatcgttac aatatggctg tcaacaatct tagctacact
     1741 aaagaacgtg cggagaaata cctctatgcc gcaccaattg cccaaaatcc taatgtcctt
     1801 gtcgtgaaga aagatgactc tagtatcaag tctctcgatg atatcggtgg aaaatcgacg
     1861 gaagtcgttc aagccactac atcagctaag cagttagaag catacaatgc tgaacacacg
     1921 gacaacccaa ctatccttaa ctatactaag gcagacttcc aacaaatcat ggtacgtttg
     1981 agcgatggac aatttgacta taagattttt gataaaatcg gtgttgaaac agtgatcaag
     2041 aaccaaggtt tggacaactt gaaagttatc gaacttccaa gcgaccaaca accgtacgtt
     2101 tacccacttc ttgctcaggg tcaagatgag ttgaaatcgt ttgtagacaa acgcatcaaa
     2161 gaactttata aagatggaac tcttgaaaaa ttgtctaaac aattcttcgg agacacttat
     2221 ctaccggcag aagctgatat taaataattt cttgaaatca tccattctga gtaaggtggg
     2281 tggtttctca gtttttaggg atatagtttt aaactatata tctgactatc taataacaat
     2341 ttgtgaaatc aaacaaattg tgagatacta gtacggtatt atttttaagg agaaagaatc
     2401 atgaaaatca aaaaatggct tggtctagca gcccttgcta cagtcgcagg tttggctctt
     2461 gcagcttgcg gaaactcaga aaagaaagca gacaatgcaa caactatcaa aatcgcaact
     2521 gttaaccgta gcggttctga agaaaaacgt tgggacaaaa tccaagaatt ggttaaaaaa
     2581 gacggaatta ccttggaatt tacagagttc acagactact cacaaccaaa caaagcaact
     2641 gctgatggcg aagtagattt gaacgctttc caacactata acttcttgaa caactggaac
     2701 aaagaaaacg gaaaagacct tgtagcgatt gcagatactt acatctctcc aatccgcctt
     2761 tactcaggtt tgaatggaag tgccaacaag tacactaaag tagaagacat cccagcaaac
     2821 ggagaaatcg ctgtaccgaa tgacgctaca aacgaaagcc gtgcgcttta tttgcttcaa
     2881 tcagctggct tgattaaatt ggatgtttct ggaactgctc ttgcaacagt tgccaacatc
     2941 aaagaaaatc caaagaactt gaaaatcact gaattggacg ctagccaaac agctcgttca
     3001 ttgtcatcag ttgacgctgc cgttgtaaac aataccttcg ttacagaagc aaaattggac
     3061 tacaagaaat cacttttcaa agaacaagct gatgaaaact caaaacaatg gtacaacatc
     3121 attgttgcaa aaaaagattg ggaaacatca cctaaggctg atgctatcaa gaaagtaatc
     3181 gcagcttacc acacagatga cgtgaaaaaa gttatcgaag aatcatcaga tggtttggat
     3241 caaccagttt ggtaataaga aacagggagg tgggagagaa aattccacct cttgcttttg
     3301 tatagagtat agattgtaaa gaagactatt cgttcataga aaggtagaga gaatatggtt
     3361 tttcctagcg aacaagaaca gattgaaaaa tttgaaaagg atcatgtagc ccagcattat
     3421 tttgaggttt tgcgtacctt gatttctaag aaatcagtct ttgcccagca ggttggactc
     3481 aaggaagtcg caaattatct gggtgagatt ttcaagcgtg ttggagctga agtggagatt
     3541 gatgagagct atacagcgcc ctttgtcatg gcacatttca agagttcgcg tccagatgcc
     3601 aagaccttga ttttctataa ccactatgac actgtgccag cggatgggga tcaggtctgg
     3661 acagaggatc cttttacgct ttcggtccgc aatggcttca tgtatgggcg tggggttgat
     3721 gacgacaagg gtcatatcac agctcgcttg agtgctttga gaaaatatat gcagcaccat
     3781 gatgatttac ctgtcaatat cagctttatc atggagggag cggaggaatc ggcttcaaca
     3841 gacctagata agtatttgga aaagcatgca gacaaactcc gtggggcgga tttgttggtc
     3901 tgggaacaag ggaccaaaaa tgccttggaa cagctggaaa tttctggtgg caataagggg
     3961 attgtgacct ttgatgccaa ggtaaaaagc gctgatgtgg atatccactc gagttatggt
     4021 ggtgttgtgg aatcagctcc ttggtatctc ctccaagcct tacagtctct tcgtgctgcg
     4081 gatggccgta tcttggttga aggcttgtac gaagaagtac aagagcccaa tgaacgagaa
     4141 atggccttgc tagaaactta tggtcaacga aacccagagg aagttagtcg gatttatgga
     4201 ttggagttgc ctctcttaca ggaggagcgg atggcctttc taaaacgttt ctttttcgat
     4261 ccagcgctta atatcgaagg aatccagtct ggttatcaag gtcagggtgt taagactatt
     4321 ttacctgcag aagccagtgc caagctagag gttcgtctgg ttccgggcct agaaccgcat
     4381 gatgttctgg aaaaaattcg gaaacagcta gacaaaaatg gctttgataa ggtagaatta
     4441 tactatacct tgggagagat gagctatcga agcgatatga gcgcaccagc cattctcaat
     4501 gtgatcgagt tggccaagaa attctatcca cagggcgttt cagtcttgcc gacgacagcg
     4561 gggacaggac ctatgcatac ggtctttgat gccctagagg taccaatggt tgcattcggt
     4621 ctaggaaatg ccaatagccg agaccacggt ggagatgaaa atgtgcgaat cgctgattat
     4681 tacacccata tcgaattagt agaggagctg attagaagct atgagtagag atattatcaa
     4741 gttagatcag atcgatgtga cttttcacca aaagaagaga accatcacag cggttaagga
     4801 tgtgaccatt cacatccaag aaggggatat ctacggaatc gttggatatt ctggagcagg
     4861 aaaatcaacc cttgtacggg tgattaatct cttgcaaaaa ccatctgcag ggaaaattac
     4921 cattgacgac gatgtgattt ttgacggcaa ggtgaccttg acggcagagc agttgcgtcg
     4981 taaacgtcaa gatatcggaa tgattttcca gcattttaac ctgatgagcc aaaagacagc
     5041 agaggagaat gtagcctttg cccttaaaca ctctgaactc agcaaggaag aaaagaaggc
     5101 taaagtagct aagttgttgg acttggttgg tttggcagat cgtgctgaaa actacccttc
     5161 acaactatct ggagggcaaa aacagcgtgt ggcaattgcg cgtgccttgg ccaatgatcc
     5221 aaaaatcttg atttcagacg agtcaacttc tgcccttgat ccgaagacaa ccaagcagat
     5281 tttggccttg ttgcaagatt tgaaccaaaa attaggcttg actgttgtct tgattacgca
     5341 tgaaatgcag attgtcaaag acattgccaa ccgtgttgca gttatgcagg atgggcattt
     5401 gattgaagag ggtagtgtgc ttgaaatctt ctcaaaccct aaacaacctt tgactcaaga
     5461 ctttatctca acagctacag gtattgacga agccatggtc aaaatcgaga agcaagaaat
     5521 cgtggaacac ttgtctgaaa acagtctctt ggtgcaactc aagtacgctg gagcttcaac
     5581 agacgagcca cttttgaatg aattgtacaa gcattaccaa gtaatggcta atattctcta
     5641 tgggaatatc gaaattctcg atggtactcc tgttggagaa ttggtggtgg ttttgtcagg
     5701 tgaaaaagca gcgttggcag gtgcccaaga agccattcgt caagcaggtg tacaactaaa
     5761 agtattgaag ggagtacagt aagatggaat cattgattca aacctattta ccaaatgtct
     5821 ataagatggg ttgggctggt caggcaggct ggggaacggc tatctactta actctttata
     5881 tgacagttct ttccttcatt atcggaggct tcttggggct agtggcaggt ctctttctcg
     5941 tcttgacagc gccaggtggt gtcttggaga ataaagtcgt attctggatt ttagacaaaa
     6001 ttacctcaat ttttcgtgcg gttcccttta tcatcctctt ggcaatcttg tcaccacttt
     6061 ctcacttgat tgttaaaaca agtatcgggc caaatgcagc ccttgtccca ctttcttttg
     6121 cagtctttgc cttctttgcc cgtcaggtgc aggttgtctt ggctgaattg gatggcggtg
     6181 tcattgaggc ggctcaagcg agcggagcga ctttctggga catcgtgggt gtttacctat
     6241 cagaaggtct tccagatttg atccgtgtga cgactgtgac cttgatttcc cttgttgggg
     6301 aaacagctat ggccggtgcg gttggagctg gtggtatcgg taacgtagcc atcgcttatg
     6361 gatttaaccg ctacaatcac gatgtgacca tcttggcaac cattattatc attttgatta
     6421 tctttgcaat ccaattcttg ggagatttct tgactaagaa attgagccat aaataaaaaa
     6481 gagccgcgtg gctcttttta actgatcaga ttttctgggc aaatttttta ctcaaggctt
     6541 gtccaatcaa ggcacccact agggctccga tgacaatact tgcgataaat agaaggacag
     6601 ttccagggtt tggagcgacc atgatacggt cgatatattc ttgggatttt cctcttgcca
     6661 gaagagtagc catataggct ttgggcgcaa tccacataag caagattggt cctgttgtac
     6721 taaaggcgaa aataatgaaa gaaaggaagt tctttgtttt gtccttgtat tttcctaaat
     6781 gagctactcc atctgctagg aggccacaga taattccagg aaggaaggaa ccagcaccgt
     6841 gtttagttcc caagaaaaag agggcaatga caaggccgat agtggtaatg gctccaaagc
     6901 gcggaacttt tgcgactagg atcatataga cgctaccgcc gacaagggca gtaaaggcag
     6961 gcgcataaaa catgtttcca gtttggtcaa agagattgcc caaaaggaca ccaatcccca
     7021 tgcagaggaa gtaaagaact gcaaaaagca gtgtagttaa gatagatttc ttcatgaatt
     7081 gtctcctgat aattttttca caattctcat tttatcatgg tttggtggga ttgtaaatgg
     7141 atactagaag tttttgaaaa cgcttgaaat atgatataat ggtttcatag ttatttttag
     7201 gggaatatca tgggtagatt tttagacttt gtctttaatc gtttcttttt agggatgatt
     7261 gcgacagcct tcttttggct attaacttta gcaggaggga ttatccttgg tctagcgccg
     7321 gctagtgcca ccttgatgag cttatatgca gaacatggtt atagctttcg ggaatacagt
     7381 ttgaaggagg cttggtctct ttacaagcaa aattttgtct caagcaacct gattttctat
     7441 agctttttag gtgtgggtct agttttgacc tatggtttgt atctcttggt gcaattgcct
     7501 catcagacca ttgttcattt gattgcgacc cttttgaatg tcctagtagt tgccctgatc
     7561 tttttggctt atacagtatc tttaaaatta caagtttatt ttgccttgtc ctatcgaaat
     7621 agtctcaaat tatccttgat tggcatcttt atgagtctag cagctgtggc taaggttctc
     7681 cttgggactg tgctacttgt agcaattggt tattatatgc ctgccctgct attttttgta
     7741 ggaattggga tgtggcattt ctttatcagt gatatgttgg aacctgtcta tgaaatcatc
     7801 catgaaaaat tggcgacaaa atagaatgaa gcagttttgg ctacatacgc ttctaagaac
     7861 ctatagttca gtgatgatca ttatcattgc gagttttgca atcttactct cttacgctga
     7921 ctgggattca cgtgaaaagg aagcccagag agtagcccag cgtgtaactg ctagaacagt
     7981 gagtgaaatt gaatattacc atagagagtc aacccagata gctcaggctt tagttgaaaa
     8041 tcaagctcgt atcgagggaa tctataaata ctttagcctt agcatgccag actattttta
     8101 ctggcaatta gagcggaaag cttcgcctta tatatcagtc tctctgtatg aaaatgttga
     8161 tgacctctat gttcgaaatg attttgtaac tggggtggcc attgcttttc aagattacaa
     8221 ggaagtctat gtttctacta aagacaaacg tagtggagaa aaaatcaggg ctgaggattt
     8281 caaaccagca ggaaatagtt ttgccattcc agtgtcagat ccagtgtcag atcaagactt
     8341 aggagtgatt tacatctcct tggatcctgc tgttttatac catgccattg ataatactag
     8401 aggtcatact ccgatggcag taacagtgac ctcacctttt gatacggaga tttttcatat
     8461 gggtgagaca gttgataagg agagtgaaaa ttggctagtt ggcttaactt ctcatggata
     8521 tcaggttcag gtggcagttc ctaaaaactt tgttttacaa ggaacagtga ctagctctgc
     8581 tttgattgtg ggtttgagcc ttctctttat tgtcattctt tatctgactt tgaggcagac
     8641 ttttgctaat taccaaaagc aggtagtgga tttagtagaa tccattcaag tcattgctca
     8701 aggcgaagag gggcgtcgga ttgacatttc cgagaaagat caggaattac tcctaatcgc
     8761 ggagacgacc aatgatatgt tggatcgatt ggaaaagaat atccatgata tttaccagtt
     8821 agagcttagt caaaaagatg ccaatatgcg agccttgcag gcgcaaatca atcctcattt
     8881 tatgtataat acgctggagt tcttgcgcat gtatgcagtt atgcagagtc aagatgagtt
     8941 ggcagatatc atttatgaat tcagtagtct cttgcgtaac aatatttccg acgaaagaga
     9001 gaccctcctc aaacaggaat tagaattttg ccgtaaatac agctatctct gcatggttcg
     9061 ctatcccaag tccattgcct atggtttcaa gatagatcca gagttagaga atatgaagat
     9121 tcccaagttt accttgcaac cgctggtaga aaactatttc gcgcatggtg ttgaccacag
     9181 gcggacagat aatgtgatta gcatcaaggc tcttaaacag gatggttttg tggaaatttt
     9241 ggtggtcgat aatggtagag gaatgtcggc tgaaaagttg gcaaatatcc gagaaaaatt
     9301 aagtcagaga tattttgaac accaagccag ctacagtgat caaaggcagt ctatcgggat
     9361 tgtcaatgta cacgagcgtt ttgtgctcta ttttggagac cgctatgcca ttactataga
     9421 gtctgcagag caagccggtg ttcagtatcg tattacaatt caagatgagt agaaagggag
     9481 aaaatgtata aagtattatt agtagatgat gagtacatgg tgacagaagg tctgaagcgt
     9541 ttgattccct ttgataagtg ggatatggag gtcgtcgcaa cagccagtca tgccgatgaa
     9601 gctctagaat atgttcagga aaatcctgtc gatgtcatca tttccgatgt caatatgcca
     9661 gacaaaacag ggcttgatat gattcgggag atgaaagaga tcttaccaga tgctgcctat
     9721 atcctgctct caggttatca ggagtttgat tatgtaaaaa gagcaatgaa ccttagtgtg
     9781 gtggactatt tggtcaagcc tgttgataag gtagagctgg gaaatctgct ggagaagatt
     9841 gcaggtcagc tcggcgagag agggaagaaa agtcagactc ttagtcaaga attagacgag
     9901 gctggatttg ttagttattt aggggataag gagaattggt ggataggtct atccaaggaa
     9961 aaacaaggtt ccttcaccat tccctactat gtcttgggtc aagactggca gattttcatt
    10021 tctggccacc ccctagatgg tttagtcgtt acaccttttg aagctcctta tcaagaacac
    10081 tttgaacgct ggaagctgaa tgctgagaaa accctctttt acggttctgt aaatctgcag
    10141 cagtctgaga gtctctttgc ctattacgaa ccgatttata gggttatcat tcagggaaat
    10201 ctcaatcaaa tcgtagaaga gttaaatctc ttggagaagg tagttcttga aaatacacct
    10261 cgtgtttcga ttactaaaca gctttttatc cagtttgtca tggatgtttt ccatttattt
    10321 gaacatctca aagctgatga tatgacggac attgtcaaaa ccattcatgc tattcaatcc
    10381 ttcgatgaat tggtttctta tatcaaggaa actctgatca gctttttcgg tcaataccgt
    10441 atgaatgaaa atgtggtcag tgtgctggaa gtcattggtc gtgattacca aaaagagctt
    10501 tccctcaagg atatcagtaa ggccctcttt atcaatcctg tctatctagg gcagttgatt
    10561 aagcgtgaaa ccgattcgac ctttgcagag ttactaaaca aacaacgtat taaggctgcc
    10621 cagcagctct tgctttcaac tagtgacagt atcgaagata tttgttatgc tgttggttac
    10681 agtaaccttg gatatttcta taaagttttc cgaaaattgt gcggaaaatc gccaaaagcc
    10741 taccgaaaac aggtagaaac tatactataa gatttgtatt cctttacaaa aggtgctata
    10801 atattatcag gaggtcctat catgaaaaag aaaccaattt atctatgggt tttgctaatc
    10861 ttgtctgccc ttatttcagt tccgtctctg tttggaattg tgagtccctt gcctagtaaa
    10921 gaagcccttc gtgctgctca gaaacaagtt gcaggggtca atgctcagca attagaagac
    10981 cagcttaatt atacctatag agtagcagaa gcatctcatt ctatttttaa tgttgctttg
    11041 attgtgctat ctactatttt agtggtcgta gcgattgtct tccttgttcg taaaaatttg
    11101 caatatgcaa actatactta cgttggctat gttttgttag ctattattgg ttcgatttat
    11161 ggctatgttg gtttacaaga cgctgtgcag ttggttcaag atgagagcat gcgtttgaca
    11221 gtgagtattg gttcaaaagc tgttagcatt ttctatatcg tcatcaatgt tctcttccta
    11281 gcccttgtct tctataagat gtggcgacaa cagaaagcct tggcagaaga agaggaaaca
    11341 gaagagctta cctaagtatt gacaaaaaag aactatcaag atacaatctt ggtagttgtt
    11401 ttttgattat agataaaatc atggaggtac atatgaagac aatttcttta gtttatatta
    11461 gtttgagtgg caacactgaa agttttgtga cgcgcttgaa agactatctc ttgtcccagt
    11521 acaaagggat tgaggttcaa aagattcata tcaaggattt ggtcaaggaa ggcaaaaatt
    11581 tctatgaaat ggaccatccc tatgtcgctt ttttgccgac ctatctcgaa ggtgggaatg
    11641 gcgtggataa cggagatgtt gagattttga cgacaccggt gggagatttt attgcctatg
    11701 gtaacaatgc tagtaagtgt tttggtgtgg ttgggtcagg aaatcgtaac tttaataacc
    11761 aatactgcct aacagccaag caatacagtc aacgctttgg cttccctgta ttggctgact
    11821 ttgaaatgcg aggcatgctg gaagatatca aacatgtcgc agctattatc gcagatttgt
    11881 atgagttgga aaaggagaat taatactcaa tgaaaatcaa agagcaaact aggaagctag
    11941 tcgcaggttg ctcaaagcac agctttgagg ttgcagatag agctgacgtg gtttgaagag
    12001 attctcgaat agtataaagt tcttataaga ggtggttgaa gttgttcaac tgttttttga
    12061 gtataaacag tctttaagaa cgtaaaaaag cataagttca ggtcttcaaa accttgttct
    12121 tatgcttttt atcatagaaa tatttgctga attttctctt gaaatgaaac cttatcttca
    12181 tctcgcgctt gtcccttacc ctgcttttcc gattgcgagt gcgtagataa agaagatggc
    12241 gaagccaaag aggaaaatca atcccgcaat ggcaaggtgt ttgagccaag aaggaagatt
    12301 tttgttttca cgcgttacca aggcgtaatt caaaagagca aagaaaggtg ttgtcaggaa
    12361 agagccaatc atggcaaagc ggagcatggt tgaaacctga ccagcgaaga acttgataat
    12421 gacgataccg atgatagcag tgatggtcat ccagatgttc aaagatttac gattgtcctc
    12481 tttttgactg attagcagtc ggagagattc ctgattaacg cgagaatagc catcgataac
    12541 agttataact gttccaaaga tacagaggaa ggcaataaag gtaatcaagt aacgggacca
    12601 ttcgccaaga acagaggcat acatgcccac gaattgagag atgtatttgg ctgaagcagc
    12661 ttcaaccgcc tgccctgtag gatactgaat cagtgctccc agtgccacaa agaagacggc
    12721 taggatagct gttccaatat aaccagtgtt aaagtcaaac agagcgtctt ctgtgttaaa
    12781 gttgacggtc tttctctttt cagctgacca aagtgaattg atggctgaaa tttcaatagg
    12841 agccggcatc catcctagga gggagacgat gaagggcaga gctgccattt gccaaggtgt
    12901 cttctcgaca aaatcagaac tgtattctgg atgcttgacc gccgcaatga taactgcaag
    12961 aacagtcgca atggttaagg cagacataat ccatttgacc atgccgtcta aaagtttgta
    13021 gcctccaaag agtagcatag cccaaatgat tgcaacgaga atgagggacc actgagtaat
    13081 gctaagtcca atcattggga aggcactggc gatgatagct gagcacagaa tggcaacacc
    13141 agccgtgttg accatagccg aaaagacatt gaggataaag aaaatccaga gatagagttt
    13201 tcctttttcg gcataacctt caaccaaagt ctttccagta tcagctgtgt attcagcacc
    13261 aaaacggaaa aatggatatt taaagacatt ggctaagatg accaagagaa gtagagacca
    13321 accgtaagaa ccgccagctt gagttgagga tacaatgtgg gaacctccaa cagcggcagt
    13381 tgccattagg attccaggtc ccattgcttt tagcttgctt gcccaggttg attgatttaa
    13441 ggaaatagct tgcgacatga taaatactcc tttttgaatt ttcagaataa tctgtatatg
    13501 taatctatat tctacaaaaa attttggaaa aatgcaagaa tattttgaaa aaagatagaa
    13561 aatttacaaa gaaaatctga aataactgtt atgatatagc agattgaaac tagaatagta
    13621 cacctttgct tctaaaacat tgttagaaat cgatttgact gtcctgatcg atttatcctg
    13681 ttcttatttc atttcactat agtaaggtgc agcaggataa agaaaaaccg agaagtttct
    13741 ttctcggatt tgcttattat gaggttccta ttttctatgc tccaagagtt gattgatgtg
    13801 atctactttt ttagcctctc ttttatagag aatagcccag atgatgagat agacaatcgc
    13861 aaactcgata atgagctgga ggtagaaaat ccagtggaaa gggaaccaac cagcaagagt
    13921 tgctagtggg acaaagccag ccagcataag gaagaaatga gtcagagtgg cacgaagcat
    13981 gctccagtca cggctaaata agcggttgcc aaagttgaag agcataccga tggttgccca
    14041 gataagtgtg cagtagagca agaccagggc accgtgaacc tgatgctgat ccatcacttg
    14101 gcctatgaga gagtagggat ttagtggtgc gtaggtattt ggtgcataaa tgagtgaaaa
    14161 gaggatagag aggatgaggc cgataagaac accggtagct gcatcgtgaa atacttgttt
    14221 tttcatagtt ctaatttctc cttgatggtt tttagataac ggcgtgaaga gtaggtgaag
    14281 ctttcgtttt tcaagaaaat ttctaccaga ccgtttggcg tgagcttgag gtgagagatg
    14341 gaatcgatat tgatgatttc tgattgggaa atttggataa aattggttgg caagagttta
    14401 agaacctgat agagtcgcaa atcaatgctg taggtctgac tcgcggtttc tgctagaacc
    14461 ttccgattct cgatatagaa gcgctgaatc ttgccaatct caactagata gacctgatca
    14521 tcgatttttc ctttgatttt ttctctttgg tccagatttt ctgcgaactc gatgactttc
    14581 tggacttttt cggtttcttg aggtgcttgg acaatcagct tttcctcctc gtaagtctca
    14641 ctaatctgta gttctacttt catagttttc tctccttttc agttatacaa ggttgtgatc
    14701 acttcctgta tatccttatt aaacactatt ttatagccca tggcaaggaa ccttgtctat
    14761 gtggagggat tgggctccta tgtggtggag cttttctgtt ctttctgaaa tatggtataa
    14821 tagcactaat caatttctag gaaaatagat acggaaaggg gctgaaagaa ctaggggaac
    14881 agttggaatt agaaagtgat aggtatgaaa agtggcgttg aagctgaata agtttataaa
    14941 gcgtttgaat gaagaaatgg aaagtaaata agttgacgat gaattacaaa atagatttta
    15001 tctacaattt gtatctttca aatcattgat ttgaatttta gatttaatca tgttacaatt
    15061 aaaactgaaa tcaaatagaa gaggaaaatg caaacgtggg cacactatta gcaacaagat
    15121 taaaaaatag acggaaagaa ttaaaaatgt ctcagcgaga actagctgaa ggtatctgta
    15181 aacaggggca aatcagtcga ttagagagcg gagagtttac ccctggagcg gatttcctga
    15241 atgcccttgc taagaagtta aaagtcagta tggattattt ttttgatgag caggttgtag
    15301 agaaagttga ggagttatca gaatttaaga aattagcaca gacatttatt acaaatcgca
    15361 attatgagtc tttgaaatat atatatgaat tggagaatgt aaaagctcac cgcctatctt
    15421 tagcagataa aatctacatg gaatggataa aatctctgat agatttttat ttttacggac
    15481 agaaagaaga tgcgattgta cgattagagg gggtattatc acagttaagt gtatctgatt
    15541 tgaactatct ccaagtttca aacaccctat tcaattttta ttatgatatt ggagatttag
    15601 gtcgtttcaa taaaattcgt gaaaaactag agtatcaagt aaatcacctc aatttgagta
    15661 caatcgaaga gttagaacta tctattaagt ttaactacaa cgtttgtcgt tatctatggt
    15721 tacagaaaaa tattgaagaa gctattacta aaattacagc tactataaaa caatgtaagg
    15781 cttacagaac gaattatctt ttggctgatt tgtacttatt gatgggaaat gtaagtgaaa
    15841 atttttcttc taaaagttcg gtgaaagaat attttgagac ggcatatttt ctatacaaac
    15901 ttgaggagaa catgtcaatg actctgaaag ttgagcatta cattgcagat ataacagaat
    15961 aatgaatacg gtgttcaagt gagcatcgtt tttcaaacct agttcagata caaaaaagta
    16021 tcaaacaaaa aaaaataaaa aaacattata aaaacaattg acaagctaat tttgaagtga
    16081 taaaataaat gcaagaaaac aaaaggagag gtatatgaga agtttgttta agaaaatagt
    16141 tgctgtatta gttattggct taattctgtt aggaattgcg agaacacctc aagttcataa
    16201 gatggctaga gggattgatc ctggtcctgc gaattttatt tagaaatcaa tttctactaa
    16261 ttgagtatta atgggtaaaa agattgtatg gataagaaaa atttacttgt attggttact
    16321 ggttcggtag gtgccagtaa tgtagataca tacttatatt acataaaaaa aattctataa
    16381 tgttaaagtg atactttctg aaaattctaa aaaatttata agtaaggaat taattagtta
    16441 tttttgtgat aaagtttatg atgaaatatt tgttgaagag gtagttccgc acgtttttct
    16501 gccatatgaa tctgacttac ttcttatttt accagctacg gcaaatgtga ttggcaaaat
    16561 tgctaatggt attgctgatg atttagttac agcaactgtt ttaaacttta ataaaaaaat
    16621 aattttttgt cccaatatga actctactat gtgggacaat cacatagttc aaagaaatgt
    16681 atcaattcta aaggagttgg gacatatatt tttatttgag tctaaaaaaa catatgaggt
    16741 aggattgcgt aaagcaatag attcaacatg ttcaatgtta caaccacagt cgttagtaaa
    16801 agaacttatc aaattagaaa atattgtcct tgaagaggga cattaaaaac tactgagaat
    16861 attaatgagg ggaaaaaatg gaaaattcat caatcgatgt agatatgctg ttggaagaat
    16921 tgacacaaga agcaatggtc gttgttgctg ttgataagga ctgttaattt aaacttatgg
    16981 caatatatga aaggttactg gatgttttaa attatgcagg cagtagcctt ttattatata
    17041 caaatggata aagtaaggat aatacaatga ttaataaaaa aatacaacaa gttgttttgg
    17101 aatcattaca gaattttttg aatgggaact tcatttcgcc ttgtgtagtc tatgattttg
    17161 gcttgctgga aactgtactt gatgaattta aaaatcaaat tcctgtaaca ttcaattacc
    17221 aactttttta tgccgttaaa gcaaattcaa atgagaagat acttgaattc ttagtagata
    17281 aaattgatgg agttgatgtg gcgtcattat ctgaattaga tgtggctaaa aaatttttcc
    17341 caccaactca aatttctgtt aatggtcccg cattttctta tgaaacttta tataatctga
    17401 ttaaaaaaca atataaagtt gatattaact ttttggaaca tcttcaacaa ttttccccaa
    17461 aagaatctgt tggaataaga gtaacggagc cagatgaact taataatcgt atgagtcgat
    17521 ttggaataaa tatttgcagt gataattgga ctagtaattt acaaaatcct ttaattacac
    17581 gactgcattt tcattttgga gaaaaagatg ataaatttat tgttaagtta gataaaatat
    17641 tatttaagtt acaagaaatt aataaactta gagaggttag agaaataaat cttggaggcg
    17701 gttttatgaa attatttatg gaaaatcgtt tgaaagaatt ttttctatca cttatggaaa
    17761 tctataaaaa gtacgatatt gatagtactg tgactacaat aatagaacca ggtagtgcaa
    17821 ttacttcatt ttctgcctat atgattacta gcccagttaa tgttagtgag gtgaatgagc
    17881 agcaggttat cacgttagac acatcaatat acaccaatac attatggttt gttccgcata
    17941 ttattacaac gttaaattca agtagtaaag agcgttatag tactattctc tatggtaata
    18001 cctgttatga acatgacaag tataaaatga aagtttcgct tccaaggtta actcaaaata
    18061 gcagtatagt gttttttcct gtaggagctt atataaaaag caatcattca aatttacatc
    18121 gtaatgattt tatgcgggag gtatatttgt ggacaaaaaa cttgacatat tagataaagt
    18181 taaggaatat ttaggaaata aaactactca aattctggat aatcaatata aagaattttt
    18241 gaaacttaat gatataaggc gagcgtttgg tatttcagaa aaagtattaa acaattcttt
    18301 taattttacg agtaaagaat ttaatgattt aattaataac gaaaattatt tattcgaata
    18361 tgcatgtaga attagagagg aatggagaaa aaaatgcttt aatcattctt atcgttttct
    18421 atgctcacct ataattacag atgattttct taacacgaag acattgagaa gtagccaaat
    18481 tgaatataaa tatgagcgat atttatcgaa aagttcgata ggcgatagag cggttgatgg
    18541 ctttgtttcc ttcaatactt taacagctaa tggtatgtct gctattaaac tatgtcttga
    18601 gatattaaac tctattttct tcaagaagaa gattgattta ttatattcaa ccggatatta
    18661 tgaaacaaga tttttattaa ataatcttgc taaatcaggt attagttgct atgaggtaag
    18721 taattgtgaa ttggataaag ataaatttta taatgtattc atgatggaac ccaatcgagc
    18781 cgatttaaca ttacaaaaaa ctgatttcaa gatagtagaa tattttgtta agtataaaaa
    18841 taattcaata aaagtcgtta ttttagatat ttcatatcaa ggttctaatt ttaaattagt
    18901 agaattttta gagaaattta aatttgcgaa tgtaattatt tttgtggtac gatctttgat
    18961 aaaattagat caaatgggat tagaattgac aaatggggga ataatagaag tgtttattcc
    19021 taatcatttg agaaagttga aaaattttat tgaagaggaa ttcaataaat ttagaaattc
    19081 tcacggagct aatctaagcc tctatgaata ctgtttgctt gataattctt taactttaaa
    19141 aaatgattgg aactattctg atttagttat gaaatttacg agtaattttt atgctgatat
    19201 aaaagacttg ttcatggaaa attctgatat tgaaatcatc catgaagagg gagtaccttt
    19261 tgtattttta gatttaatag gtgaaggtaa aaaagaatat gaaatgtttt ttcaatggtt
    19321 aaacttcttt tacaaacagc ttggaatcac attgtatgct agaaatagtt ttgggtttcg
    19381 gaatctaaca gtagagtatt ttggaattat tgggacagaa agatatatat ttaagatttg
    19441 tccaggtgtt tataaagggt taagttatta tttgatgaaa tttttattaa aatctttttc
    19501 aaatgaatat ttaaaaacta ctgatgaggt taatagatga aaaatttgat aaagttgcta
    19561 ataattagat tgattgttaa cttagcagac agtgtatttt atatagtagc attgtggcac
    19621 gttagcaata attattcttc gagcatgttc ttaggaatat ttattgcagt aaattatcta
    19681 ccggatttgt tactaatctt ttttggacca gttattgaca gagtaaatcc gcaaaaaatt
    19741 cttataatat caattttggt tcaattagca gtggctgtaa tatttttatt attattaaac
    19801 caaatatcat tttgggtgat aatgagtcta gtgtttattt cagtaatggc tagctccata
    19861 agttacgtga tagaagatgt gttgattcct caagtggtag aatatgataa gattgtattt
    19921 gcaaattctc tttttagtat ttcgtataaa gtattagatt ctatttttaa ttcattcgca
    19981 tcatttttac aggtggcagt aggatttatt ttattggtta agatagatat aggcatattt
    20041 ttacttgctc tatttatatt gttgttgtta aaatttagaa ctagcaatgc gaatatagaa
    20101 aacttctctt tcaaatatta caagagagaa gtgttgcaag gtacaaagtt tattttaaat
    20161 aataaattat tatttaaaac cagtatttct ttaacgctta taaacttttt ttattcattt
    20221 cagacagtag ttgtaccgat tttttctatt cgatattttg atggtccgat tttttatggt
    20281 atttttttaa ctattgctgg tttgggtggt atattgggaa atatgctagc gccaatcgta
    20341 ataaaatatt taaaatcgaa tcaaattgtt ggtgtatttc tttttttgaa cggctcaagt
    20401 tggttagtag caattgttat aaaagactat actttatcac ttattttatt tttcgtttgt
    20461 tttatgtcta aaggagtctt caatattatt tttaattcgt tgtaccaaca aatacctcca
    20521 catcaacttc ttggtagggt aaatactacc attgattcta ttatttcttt tggaatgcca
    20581 attggtagtt tagttgcagg aacgcttatt gatttgaata ttgaattagt gttaattgct
    20641 attagcatac cttatttttt gttttcttat attttttata cggataatgg attgaaagaa
    20701 tttagtatat attagaaatg tttatgttca ttcaaaagca taatgactat aactgaaaaa
    20761 gaaaagtgat atctttaagg ttgttcttct tggtggtgag attcgtgaga caacccaagc
    20821 ttttgtcgga aagattacca atgctttgat ggataggatg tactttagca agatgttttt
    20881 agtggtaacg gtatcgtgga tggacgtgta ataacctctt ctttcgagga gtattttact
    20941 aaaaaactag ccttggagcg ttccccagaa acggacttac tcattgactc ttcaaagatt
    21001 tggggagaag attttgcttc atctgttcct tgaaaaaagt cacagcagtc atcacagacg
    21061 atagtactga acaaaactat gaagagttag aaatttatac gcaggtgatt gtataaagga
    21121 tctggaaata gataagaagt tgattagtat tgacctaggt ggtacaaata ttaagattac
    21181 tgttctttca aatgacggtg agattgaaac tttgtggagt attacaacag atacaagtga
    21241 gaaaggttct caaattatat cggacatcat cagttctatt aaaaataaat tgaccgaacg
    21301 gaatattcct gatagcgacc ttcttggaat cggtatggga agttgctcat catactttcc
    21361 ttgtaaatca taggggctat aaactctccg tctacttgtc ctgcaacaat tgaagtctgc
    21421 tcaaaacgcc gtccgctaat cttttcatag actttctccc ttttaggagc ctagctttct
    21481 agtttgttct ttgattttta ttgagtatac cactatttta ctccctctgg caagggactt
    21541 tgtctatgtg gagggattgg gctcctatgt ggtggagctt ttctgttctt tctgaaatat
    21601 ggtataatag cactaatcaa tttctaggaa aatagataca gaaaggggct gaaagatgtc
    21661 tcatattatt gaattgccag agatgctggc aaaccaaatc gcggctggag aggtcattga
    21721 acgtcctgcc agtgtggtca aagagttggt agaaaatgcc attgacgcgg gctctagtca
    21781 gattatcatt gagattgagg aagctggtct caagaaggtt caaatcacgg ataacggtca
    21841 tggaattgcc cacgatgagg tggagttggc cctgcgtcgc catgcgacca gtaagataaa
    21901 aaatcaagca gatctctttc ggattcggac gcttggtttt cgtggtgaag ccttgccttc
    21961 tattgcgtct gttagtgtct tgactctgtt aacggcggtg gatggtgcta gtcatggaac
    22021 caagttagtc gcgcgtgggg gtgaagttga ggaagtcatc ccagcgacta gtcctgtggg
    22081 aaccaaggtt tgtgtggagg atctcttttt caacacgcct gcccgtctca agtatatgaa
    22141 gagccagcaa gcggagttgt ctcatatcat tgatattgtc aaccgtctgg gcttggccca
    22201 tcctgagatt tcttttagct tgattagtga tggcaaggaa atgacgcgga cagcagggac
    22261 tggtcaattg cgccaagcaa tcgcagggat ttacggtttg gtcagtgcca agaagatgat
    22321 tgaaattgag aactctgacc tagatttcga aatttcaggt tttgtgtcct tgcctgagtt
    22381 gactcgggct aaccgcaatt atatcagcct cttcatcaat ggccgttata ttaagaactt
    22441 cctgctcaat cgtgctattt tggatggttt tggaagcaag cttatggttg gacgttttcc
    22501 actggctgtc attcacatcc atatcgaccc ttatctagcg gatgtcaatg tgcatccaac
    22561 taagcaagag gtgcggattt ccaaggaaaa agaactgatg actctggttt cagaagctat
    22621 tgcaaatagt ctcaaggaac aaaccttgat tccagatgcc ttggaaaatc ttgccaaatc
    22681 gaccgtgcgc aatcgtgaga aggtggagca aactattctc ccactcaaag aaaatacgct
    22741 ctactatgag aaaactgagc cgtcaagacc tagtcaaact gaagtagctg attatcaggt
    22801 agaattgact gatgaagggc aggatttgac cctgtttgcc aaggaaacct tggaccgatt
    22861 gaccaagcca gcaaaactgc attttgcaga gagaaagcct gctaactacg accagctaga
    22921 ccatccagag ttagatcttg ctagcatcga taaggcttat gacaaactgg agcgagaaga
    22981 agcatccagc ttcccagagt tggagttttt cggacaaatg cacgggactt atctctttgc
    23041 ccaagggcga gatggacttt acatcataga tcagcacgct gctcaggaac gggtcaagta
    23101 cgaggagtac cgtgaaagca ttggcaatgt tgaccaaagc cagcagcaac tcctagtgcc
    23161 ctatatcttt gaatttcctg cggatgatgc cctgcgtctc aaggaaagaa tgcctctctt
    23221 agaggaagtg ggcgtctttc tagcagagta cggagaaaat caatttattc tacgtgaaca
    23281 tcctatttgg atggcagaag aagagattga atcaggcatc tatgagatgt gcgacatgct
    23341 ccttttgacc aaggaagttt ctatcaagaa ataccgagca gagctggcta tcatgatgtc
    23401 ttgcaagcga tctatcaagg ccaatcatcg tattgatgat cattcagcta gacaactcct
    23461 ctatcagctt tctcaatgtg acaatcccta taactgtcct cacggacgtc ctgttttggt
    23521 gcattttacc aagtcggata tggaaaagat gttccgacgt attcaggaaa atcacaccag
    23581 tctccgtgag ttggggaaat attaaaagta taaaaaagtc tgggaaaaat tttcaaaatc
    23641 aaaaaaacgc ataaaatcag gtgttcaaaa accttgattt tatgcgtttt atcatggaaa
    23701 tagttacttc attttttcct aattcttttc gaaactcttt ttaaacgacg tcagttttat
    23761 cagtaatctc aaaacagtgt tttgagctaa ttttgccagt tttgtctgta acatcgaagt
    23821 tgtgttttac cactctgcga ctggtttcct agtttgctct atgattttca cagagcatta
    23881 aattgcgatt ttgccaagtt tctttattcg tctaaaagta gagtctgttc tatgcgtcta
    23941 atgtacgaat caggttgacc atttcaatag ctccttgtgc acactcagaa cccttatttc
    24001 ctgctttagt accagctcgt tctatggctt gttcaattgt atctgtcgtt agcacaccaa
    24061 acataacagg aatttcgcta tttaaactga tttgggcgat tcccttagat acctcgctac
    24121 atacataatc ataatgactt gtattccctc taatgacagc tcccaagcag ataattgcat
    24181 catatttttt actttttgcc atttttgatg caatcagtgg tatttcaaaa gctcctggaa
    24241 cccaggctac ctctatatct ttctcgttta cattctctct tttgagatta tctagtgctc
    24301 cagataataa ttttgaagtt ataaattcat taaatctcgc tacaacaata cctattttaa
    24361 tattgtttgc tactaaatta ccttcataag tgttcattta tttttcctcc atatttaaaa
    24421 tgtgacccat tcgatttttc tttgtttcta aataaaaact atcgtaagga ttggcttcta
    24481 tttcgattga tattctactg gaaatggtaa ttccatattt ttctaactgt tcaaccttgt
    24541 caggattatt tgtcagtaaa tgaagtgact gaagtcccag atctttaagc atttttgctc
    24601 caatatgata ttctcttaaa tcaccttcaa agcctaatgc aagattggca tcaagcgtat
    24661 ccatgccttg atcttgtaaa tgataggctt ttaatttatt gataagtcca attcctcgtc
    24721 cctcctgtcg caagtaaagt aagacacccg aaccattctc aacaatcatt ttcatagcct
    24781 tatcgaattg ctgtccacaa tcgcaacgta aagagcctaa aacatctcct gttaaacatt
    24841 cggagtggac ccgacataat acattggctt catcctctat atttcccata ataagagcaa
    24901 gatgatgttc cccatttagt ttatctatat agctaattgc tttgaaatta ccgtatctag
    24961 taggcatatt gacagttgaa actcgttcta ccagctgatc atatactttt ctatattctt
    25021 gtaattcttt gatggtaatt agtggaatgt tgtgtttttt cgagaactga attaaatcat
    25081 ctgttctcat cattttgcca tcatgattca ttatttcaca acataggcca cactctttta
    25141 gtccagctaa ttttaataaa tcaacagttg cttctgtgtg tccatttctt tctaggacac
    25201 cacctttttt tgcaattaaa ggaaacatgt gtcctggcct gcgaaaatca gagggtgtta
    25261 tatcttcagc tacacacata cgtgcggtca gtcctctttc ctcggcagaa atacctgtgg
    25321 tcgtttcttt ataatcaatt gaaactgtaa aagcagtctt atgattatct gtattgtttt
    25381 caaccatagg tgaaagcatt aattgattag ctaaactttc gctcataggc atacaaatta
    25441 atcctttggc ataagtagcc ataaaattaa cattttctgt tgtagctgct tgtgcagaac
    25501 aaattaagtc tccttcattt tctctatcct tgtcgtctat aacaagaaca agtcgtccct
    25561 tctgcaatgc ttctaatgct tcttgtattt ttcgatattc cattgactga ttatcctttc
    25621 tgctaaaatc cattttgata taatagttcc ttagatattt ctgattttgg agagttatcc
    25681 atcagttttt gcacatattt atctaagata tcattttcaa gatttactgt actcccgact
    25741 tgtttactct taagaatggt ttgttccaag gtatgaggga taacagatac tgaaaagttt
    25801 actttggaga ctttagcgac agtcagacta atgccgtcaa ttgtaataga tcctttttca
    25861 actattaaat ctaaaatttc tttttgtgtg ttgatttgat accatacagc attatcatct
    25921 ttttttattg acgagatttt tcctgtacca tcaatgtgtc ctgtaacgac gtgaccccca
    25981 agtcgaccgt tgacagataa ggctctttct agattcacct cacttccatg ttttaataga
    26041 gtaagagctg ttcgactcca tgtttcattc attacatcaa ctgtaaagga ttgatgattg
    26101 aaatgagtaa ctgtaagaca gataccattt actgctatac tatcgcctaa atggatatcc
    26161 gttaatattt ttgaggcttt aattgatagt ttacaattac gagagtcttt ctgtattctt
    26221 tcaacttttc cgatttcttc aattattcct gtgaacatgg ataaatcact tcactttcta
    26281 tgagatagtc atttcctatt tgagaaaatg cataaggttt caatctaata gcgtcatttg
    26341 gcaaagaaat accttcacct ccgacaggaa acttggcact acctccaaaa acttttggtg
    26401 caatatatat tttcagctca tcaacaattt gttgttccaa agcactccaa ttcattagac
    26461 tgcccccttc tagaactagg ctatcaatct gcatgtttcc tagatgttgc attaaactcg
    26521 ataagtctat atgattgcct tttttcttta tggaaagtat ttcacagcca tgattttgat
    26581 atagcttcat tttatttttg tcttcagagg aagtggcaat gtaagtttta atatcatttg
    26641 ctgtttttac gattttagag gtaagaggag ttcgtaaatg tgtatcgcat atgatacgga
    26701 taggattttt cccttcctcc aatctacatg tcagcaaagg atcgtcttga ataacagtat
    26761 tgactcccac cataattgca ctaacatggt gtcgtaactg atgcacatgc tttcttgctt
    26821 cttcttcagt aatccatttg gattgatttg ttttagtggc tatttttcca tccattgaca
    26881 ttgcatattt cataaaaaca tagggtacat gctgggtaat atactttcta aaacttttta
    26941 ttaagttaag acactcattt tctaaaattc caacagtaac ttgaagatta ttttcctcaa
    27001 gtatctttac tccttttcca gatacaatag gattacagtc taggcttcca atgactactc
    27061 ttgtaatacc actatcgatt atagcatcta tacagggagg tgttttcccg aagtgacaac
    27121 agggttcaag tgttacataa agcgtcgctc cgacagggga ttctctacag tttttaagag
    27181 catttctctc agcatgtggg ccaccaaaaa actcatgata accttgtccg ataatgtgat
    27241 tatcttttac aataactgcg ccgaccatag gattgggatt gacgtaacca gccccttttt
    27301 gtgccagttt tattgctaat ttcatatatt ttgaatcgct catctcgcta cctccaaaaa
    27361 aatatacctt gaatagggga ctactcaagg catacaaaag aaaacttatg cgattaacaa
    27421 aaatgctctg aaatgacaag taatcatttc agagcacgca aaaagcacaa atatactttt
    27481 atcttctttc atccagacta tactgtcggc tttggaattt caccaaatca tgcctttcgg
    27541 ctcgtgggct ataccaccgg tagggaattt caccctgccc tgaagatagt tattcaatta
    27601 cagatgatta tagtacttaa ttttgaatat gtcaacagat aaataccgat tgtttttgat
    27661 atactgtatt tgtgataatc gattctcgct cctcggataa agaaaatatg atatactaga
    27721 taaacgaaat aagagagaag gaatactatg tacgcatatt taaaaggaat cattaccaaa
    27781 attactgcca aatacattgt tcttgaaacc aatggtattg gttatatcct gcatgtggcc
    27841 aatccttatg cctattcagg tcaggttaat caggaggctc agatttatgt gcatcaggtt
    27901 gtgcgtgagg acgcccattt gctttatgga tttcgctcag aggatgagaa aaagctcttt
    27961 cttagtctga tttcggtctc tgggattggt cctgtatcag ctcttgctat tatcgctgct
    28021 gatgacaatg ctggcttggt tcaagccatt gaaaccaaga acatcaccta cttgaccaag
    28081 ttccctaaaa ttggcaagaa aacagcccag cagatggtgc tggacttgga aggcaaggta
    28141 gtagttgcag gagatgacct tcctgccaag gtcgcagtgc aagcaagtgc tgaaaaccaa
    28201 gaattggaag aagctatgga agccatgttg gctctgggct acaaggcaac agagctcaag
    28261 aaaatcaaga aattctttga aggaacgaca gatacagctg agaactatat caagtcggcc
    28321 cttaaaatgt tggtcaaata ggagcagaga atgacaaaac gttgttcgtg ggtcaagatg
    28381 accaacccgc tctacatcgc ctatcatgat gaggagtggg gccagcccct ccatgatgac
    28441 caagtattgt ttgagttgtt gtgtatggaa acctatcagg caggcctgtc ttgggaaacg
    28501 gtactcaaca aacgccaagc tttccgagaa gtctttcata gctatcaaat tcactcagtc
    28561 gcagagatga ctgacactga attggaagcc atgctggaga atccagctat cattcgaaat
    28621 agagccaagc tttttgctac acgcgctaac gcccaagcct ttctacagtt acaggcagag
    28681 tacggctctt ttgatgccta tctttggtct tttgttgagg ggaaaactgt cgttaacgat
    28741 gttcctgatt atcgccaagc gccagctaaa acacccttat ctgagaaatt agccaaagat
    28801 ctcaaaaaac gaggcttcaa gttcacaggc ccagtcgccg tattgtcttt tctacaggct
    28861 gcagggctag ttgatgacca cgagaatgat tgtgagtgga aaggtcttaa atgatgtcta
    28921 acaaaaataa ggaaattctg atttttgcga ttctctatac agtcctcttt atgtttgatg
    28981 gcgttaaatt gctggcttct ttaatgccat ctgccattgc aaattatctt gtttatgtag
    29041 ttttagctct atatggctcc ttcttgttca aggatagatt gatccaacaa tggaaggaga
    29101 ttagaaagac taaaagaaaa ttcttctttg gagtcttaac aggatggctc tttctcattc
    29161 tgatgactgt tgtctttgaa tttgtatcag agatgttgaa gcagtttgtg ggactagatg
    29221 gacaaggtct aaatcagtct aatattcaaa gtacctttca agaacaacca ctactgatag
    29281 ctgtttttgc ttgtgtcatt ggacctctgg tagaagaatt atttttccgt caggtcttat
    29341 tgcattactt gcaggaacgg ttgtcaggtt tactaagcat tattctggta ggacttgttt
    29401 ttgctctgac tcatatgcac agtttggctc tatcagagtg gattggtgca gttggttact
    29461 taggtggagg ccttgccttt tctattattt atgtgaaaga aaaagagaat atctactatc
    29521 ccctacttgt tcacatgtta agcaacagcc tctccttaat cattttagct atcagtatag
    29581 taaaatgaaa tgagaacagg acaaatcgat ttctaacaat gttttagaag tagaggtgta
    29641 ctattctagt ttcaatatac tgtaatatgt gatgaaaatg ccagtaatga taccgagaaa
    29701 aaagctgaga aacttttccc agctttattt gttatagtca aagagaatga cttgttcctg
    29761 tgcatctaca tgagcatgga ccccaaaggg tacaattgct cttggagttg cgtggccgac
    29821 attcagatta tagacaatcg ggatattgct gtcaatgata tccaatagtg cctctttata
    29881 gtcgtcatgg aaagtttcat ccataggttt tccgaccaag agtccattga tgaccgcgaa
    29941 tatgccagtg tcctttaaag ttagcaacat ctttttgaag tcttctggct taggcttttc
    30001 ttcgcttgtt tcgagcaaga ggattttccc ttcccagtct gacaagtcag ggaaaagttt
    30061 gtatttttgg cagagttccg tgctatctgc gtatcgagag ttgtcaaaga tatcgtagag
    30121 ggattcgagg caaccaccga ggattttccc ctcgaactgg gcacttcctt gcaacaagtc
    30181 aaaacctgta tttgtatgac tgacacgagg tgttcccagg gccgtgggac taaaatcagt
    30241 tcgttcctca taccaaacgt cactagggcg gatttctgaa attcttcccg tctcaatcaa
    30301 ttctttaaag tagtgaaggc tataggctag catttctttg tctaattcac aaatgtctgc
    30361 taaaaaggat tgaccataaa aagtcttgat tcctaattta tgcaacatga ggtggttcat
    30421 ggttgtatcc gagaagccaa gaaaaatttt ttgcttgata accttttgga gttggtcatt
    30481 ttcaaaaaga taaggtagca agcgataggt atcgtctcca ccgatggcac ataggatcat
    30541 gtcgatgcta tcatcagaaa aggcatgaat caaatcctct gcacgagctt caggatggtc
    30601 cttgataaag tctaatcctt ttaacgaatg gggcaaaaag atgggattga gtcccagatc
    30661 cttgagacgt tggataccca agtccacttc gtgtttgaca aaatcctctc cgataatgcc
    30721 actagataaa ctaacaatac caatagtaga aaccatatct catcctccta gaaatagatt
    30781 gagcctattt tatcacaaaa tataagagaa agctatgtgg gatttcagaa gaatactttt
    30841 aatactcttc gaaaatctct tcaaaccacg tcagttttat ctgcaacctc aaagctgtgc
    30901 tttgagcaac ctgcagctag cttcctagtt tgctctttga ttttcattga atataactca
    30961 aaaaagtaag tgaaaaagca accgcacctg cagttgcttt tatcgttttc ttattcttga
    31021 tagcgtgttg gtcctgcact tgcactacgg atattcaagc gtttcttgag atagaagcga
    31081 agggctagga gggctgctcc aataatagct agtggcaatg gatccagtac tgggttaagg
    31141 ctagctggta ggaagcttgt tgcaaagaag acaagcaacc aaaggaacat agaagctagg
    31201 ataactagta cagatttcca gaaaggtgga cgttgactgc gatccatatc tggtccatag
    31261 tattggtaaa caaagtagta catcaagtag aaggcaaatc caccaaccag tccaactaat
    31321 agaagagtaa tcaatccata gccgaaagct tggtctgccg caaagaaggt tgtgagggcg
    31381 ctgacaaggg caaagaggct agtgatgaaa agagctgagt ccataatcat cagttttggg
    31441 tcatcatttt cttttggatg ctctttttcg tactgctctt tgacagtgaa gctatgagcc
    31501 caatgagttg gtgcgccgta tagggaacgg gcagttgtac ctttagattg ctcctcaagg
    31561 atttggggaa tgacttcctc aaaaatagtc tggatttcag cgtctgtttt cccatctttg
    31621 atgaattgtt gggtagcaat gtggacaaac tcttggtttt tcttagttaa tttttgtaga
    31681 tcaatttgag acataggaac tcctcttaga accatttttt atggatgaga tagagagtga
    31741 gcgagacact catagcaaag gcgataaaga cgattaacca gaaggcattt ggctctccgt
    31801 ttagggggat ttcattatcc ttaaagttca tcccgtaggc agaaaagacc atggttggga
    31861 tggacatgac gatggtcaca agggccaagg ttttcatgat gttgttctgg ttgttagaaa
    31921 tgatagaggc aaaggtctct gtcatagaat gcaagacgtt tccataaata tctgccatct
    31981 cgatggcctg ttgggtttca atcagggtgt cttcaagcag gtcttcgtcc tcaaggtatt
    32041 tcttgatatt gctggttgaa ctggtcaatt tcttaatcac gcgctcattt gttttgaggg
    32101 aggccttgaa atagacgata gttttttcca attccatgag ctcaatcaat tcttcattac
    32161 gagttgattg atgcagttga ctttcgattt gttcactctt gcggtcgatt gaacgaaggg
    32221 ctgttaggta aagctctgca ttgcgataaa gaatttgaaa gataaaacgt gaacgcatga
    32281 aggtatagaa attacgcaat cgacggttga taaagacatc aaggacaggt agtggttcca
    32341 aacacgtagt gataatggtt tcctcagtga tgataatacc aagcgggatg gttacgtagt
    32401 aggtgcggtt atttctttcc tccgtgaccg gcacgtctac gataatcagg gtatactcgt
    32461 cttcaatggt aatacgagac atttcttccg catcgagcgg tgctcgaagg tcagcaatat
    32521 caatatcgaa ggtgttggcg atttcgagtg attcattttg agtcggattg acgagattga
    32581 tccaagtacc cggttcaagc gtatcgatct ctttaaattc agttgttgta gagagaaaaa
    32641 cttgtttcat atcccttatc ctttctcatt tttcagattt tttcacactg tactattata
    32701 ctacaaaatc ggccttttgg gtaatagaat ctcacttttt ttggtataat ggtaagcaat
    32761 aatggactag aaagaacaaa gatgcaagat aaaattgtca ttcatggggc gcgtgcccat
    32821 aatttaaaaa atattgatgt ggagattccg cgagacaagt tggttgtcgt gactggcttg
    32881 tcaggttcag ggaagtccag tctggctttt gatactctct atgcggaggg acaacgtcgc
    32941 tatgtagaga gtttgtccgc ctacgctcgt cagttcttgg gaaatatgga aaaaccagat
    33001 gtagatgcca ttgatggtct cagcccagct atttccatcg accagaaaac gactagtaaa
    33061 aatcctcgct cgacggtggg aacgacgact gaaatcaatg actatctgcg tctcctctac
    33121 gcacgtgtgg ggacgcctta ctgtatcaac ggacatggag ctatcaatgc ttcttctgtg
    33181 gagcaaatcg ttgataaggt tttggagtta cctgaacgcc agcgcttgca gatcttggct
    33241 cctgtcatcc gcaagaaaaa aggccaacat aagagtgtta tcgagaaggt tcagaaagac
    33301 gggtatgttc gtgtccgtgt ggatggggaa gtctatgatg tgaccgaagt gccagagttg
    33361 tctaagagca agcaacacaa tatcgatgtc gtggttgacc gtattgttat caaggagggc
    33421 attcgtagtc gtctctttga ttccattgag gctgcccttc gtattgcaga aggttatgtc
    33481 attatcgaca ccatggacga ctcggagttg ttgttctctg agcattatgc ctgtccagtt
    33541 tgtggtttta ctgtcccaga gttagagcct cgtctctttt ctttcaatgc tccttttggc
    33601 tcttgtagtg agtgtgacgg cttgggcatc aagctggagg tggatactga tttggtagtg
    33661 ccagatgcta gcaaaacctt acgtgaggga gcgctagcac cttggaatcc tatctcatcc
    33721 aactactatc caaacatgtt agagcaggcc atgaaagtct ttggagtggc tatggataag
    33781 ccttttgagg acctgtcaga agaagataag aacttgattc tctatgggtc agatggtaag
    33841 gaattccatt tccactatga gaatgaattt ggtggcgtgc gcgatatcga cattccgttt
    33901 gagggagtta tcaataatat caaacgtcgt taccatgaaa ccaatagcga ttacactcgc
    33961 actcagatgc gtctctacat gaatgagctg acctgcggaa cctgtcaagg ctatcgtctc
    34021 aatgaccagg ccttgtctgt ccgtgtgggc ggccagcaag ggccacatat tggagaaatc
    34081 tcagacctgt ctatcgctga ccacttggac ttggtgagcc agttaacttt gtctgaaaat
    34141 gaagccatca ttgctcgtcc cattctcaag gaaatcaagg atcgtttgac cttccttaat
    34201 aatgtgggtc ttaactatct aaccctgtca cgttcagcag gaaccctttc aggtggggaa
    34261 agtcagcgca ttcgtttggc aacccagatt ggttccaacc tatcaggtgt cctctatatc
    34321 ctagacgagc cgtcaatcgg tcttcaccag agggacaatg atcgcctgat tgccagtctg
    34381 aaaaagatgc gtgacttggg caatactctt atcgtggtgg aacacgacga agataccatg
    34441 cgtgaggctg attatctgat tgacgttggt cctggtgccg gtgtttttgg tggtgagatt
    34501 gttgcagcag gtacacctaa gcaagtggct cgcaacagca agtctatcac aggtcagtac
    34561 ttgtcaggca aacgtgtcat cccagtacca gaagagcgcc gtgtcggaaa tggtcgtttt
    34621 attgaagtga taggagcgcg tgagaacaac ttgcaaaatg tcacggctcg ctttccacta
    34681 ggaaaattta tcgcagtgac aggtgtgtcg ggttcaggga aatcgactct aatcaacagc
    34741 attctcaaaa aagccattgc ccagaagctc aaccgtaatt cagacaaacc tggtaagttt
    34801 aagactatta cagggattga gcatgtcgac cgtttgattg atattgacca gagccctatc
    34861 ggacggacgc cgaggtctaa cccagctacc tatacaggag tttttgacga tatacgtgac
    34921 ctttttgctc agacaaatga agccaagatt cgaggctaca agaaggggcg cttcagtttc
    34981 aacgtcaagg gaggtcgctg tgaagcttgc tcaggtgacg ggattatcaa gattgagatg
    35041 cacttcttgc cagatgttta tgtggcttgt gaagtttgcc acggaacccg ctataacagt
    35101 gaaaccctag aagttcacta caaggaaaag aatatttcgc aggtcttgga tatgacggtc
    35161 aacgatgcgg tagaattttt ccaacacatt ccgaaaattc aacgcaaact ccagaccatc
    35221 aaggatgtag ggctaggcta tgtgaccttg ggacagccag ctaccaccct ttctggggga
    35281 gaagcccaac gtatgaagtt agctagcgaa ctccacaaac gatcgacagg aaaatctttc
    35341 tacattctgg atgagccgac gacagggctt catacagagg acattgctcg cctgctcaag
    35401 gttttagctc gctttgtaga cgatggcaat acagtcctcg tcatcgagca caatctggat
    35461 gttatcaaga cggcagacca tatcattgac ttgggacctg agggcggtgt cggtggtgga
    35521 accatcatcg taacaggaac tccagaagaa gtagctgcca acgaagccag ctatacagga
    35581 cactatttga aaggaaagtt acatcatgaa taaacgcgta caagcatttc tagctaaaat
    35641 gcaagaaaaa gaactagatg gtatcatcat caacaatctt aaaaacgtct attatttgac
    35701 tggtttttgg ggctcaaacg gaacagtctt tatcagtcgt gaccgtcagg tcttagtgac
    35761 agactctcgc tatatcatcg cagctaagca agaaaccagt ggttttgaga ttgtggctga
    35821 tcgtgatgaa ttggctgtca ttgcaggaat tgttaaggac atgggcttga ctcgtatcgg
    35881 ttttgaagat gagatttcag tgtcttatta ccaccgtatg caggcagctt ttgcaggttt
    35941 gaacttgctt ccacaaactc agtttgtgga aggtcttcgt atgattaagg atgaggcaga
    36001 gattgcagcg attcgcaagg cttgttctat ctcagaccaa gctttccgcg atgcgcttga
    36061 ctttatcaaa ccaggaaaaa ctgaaattga gattgccaac ttccttgatt tccgcatgcg
    36121 tgagttggga gcatctggct tatcttttga tacgatccta gctagcggta tcaattcttc
    36181 taaaccccat gcccatccaa tgcacaaacc agtggagttg ggagaagcca tcaccatgga
    36241 cttcggctgt ctctatgacc actatgtcag tgatatgacc cggactatct atctagggca
    36301 tgttagcgat gagcaggcag agatttacaa tacggttcta aaagctaacc aagccttgat
    36361 tgaccaagct aaggcaggct taggtttccg tgactttgac aaaatccctc gtgatattat
    36421 cattgaggca ggttatggtg actactttac tcacggcatt ggccacggta ttggtctgga
    36481 tatccatgag gaaccctact ttagtcagac ttctacagaa actattaaga caggtatggc
    36541 cttgaccgat gaaccaggta tctatatcga aggcaaatat ggcgttcgta tcgaggatga
    36601 tatcctgatt acagagacag gttgtgaatt attgacccta gctccaaaag agttgatagt
    36661 catttagttg tttgtcaaga aaaaagtacg aaaatgacga aaaaagtcaa aaaaaattaa
    36721 aaataggtcg caagtcggat gttttttatg gtataataga ctaaactgat agtaacatgt
    36781 agcgaaaggg gtaggtacat gattaaaatt tatacagtct caagttgtac tagctgtaaa
    36841 aaagcaaaaa cctggctcaa tgcccaccag ttaagttata aagaacaaaa ccttggtaaa
    36901 gaaggaatta cgagagaaga attactggat attctaacca aaacagataa cggaatagcc
    36961 agcatcgttt cgtctaaaaa tcgctatgcc aaagcccttg gagtggatat tgaagatttg
    37021 agtgtcaatg aagttctcaa tctgattatg gaaacaccga gaattttaaa gagcccaatc
    37081 cttgtagatg aaaaacgcct gcaagttggc tacaaggaag acgatattcg tgccttccta
    37141 ccacgctctg tccgtaatgt agaaaatgca gaagcacgtt tgcgtgcagc tctataaaca
    37201 tcaaggctgg gagcacttcc cagtcttatt ctattttaat ttcaaaaaga aagaagaaag
    37261 aaatgaaaaa aatagttctt gttagtctag ctttcctttt tgtcctggtt ggttgcggac
    37321 agaaaaaaga aactggacca gctacaaaaa cagaaaaaga tacgcttcag tcggcattgc
    37381 cagttattga aaatgctgag aagaatacag ttgtaactaa gactttggtc ttgcccaagt
    37441 cagatgatgg tagccagcag acacaaacaa ttacttacaa agacaagact tttttgagtc
    37501 tagctatcca acaaaaacgt ccagtctctg atgagttgaa gacttatatt gaccaacatg
    37561 gagtggagga aactcaaaaa gctcttcttg aagcggagga gaaggataag tctatcattg
    37621 aagctcgtaa attggcaggt ttcaaacttg aaacaaaact attgagcgca acggaacttc
    37681 aaacaacgac tagttttgat tttcaagttc tggatgtcaa gaaggcttcc cagttggaac
    37741 atctgaagaa tattggtttg gaaaatcttt tgaaaaatga accaagcaaa tatatttcag
    37801 atagattggc aaatggcgcg acagaacaat agaaaatcca aataaataga ctgcctgaat
    37861 tgtagaaggt aaggaattat gctataatgg tactattcta aggaaagagg gtgttagaat
    37921 gggatttact gaagaaacag tacgttttaa attggacgat tccaataaaa aagaaattag
    37981 cgaaactttg acagatgttt atgcttcgtt gaacgataag ggttacaacc caattaacca
    38041 aatcgtaggt tacgtattga gtggagaccc tgcctacgtt cctcgttata ataatgcacg
    38101 aaatcaaatc cgtaagtatg agcgtgatga aatcgttgag gaattggttc gctactacct
    38161 caaaggacaa ggagtcgatc tataacctat gagaattatg ggattggacg tcggttcaaa
    38221 aacggtaggg gtggcgatta gcgatccgct tggttttaca gctcaagggc ttgaaatcat
    38281 ccagataaat gaagaacaag gccaatttgg ttttgaccgc gttaaggaat tggttgatac
    38341 ttacaaggtg gaacgatttg tagtgggctt gcctaaaaac atgaacaata caagtggacc
    38401 gcgcgtagaa gctagtcaag cctacggagc aaagctagaa gagttttttg gtttaccagt
    38461 agactatcag gatgaacgct tgacaacagt ggctgctgag cgcatgttga ttgaacaagc
    38521 agatatcagt cgcaataagc gcaagaaagt cattgataag ttagcagctc agctgatttt
    38581 acaaaattat ttagatagaa aattttaata taaaggagag gctatgtcac acgatcataa
    38641 ccacgaccac gaagaacgtg aactaatcac actagtagat gagcaaggaa atgaaacctt
    38701 gtttgaaatc cttttgacaa ttgatggaaa agaagaattt ggtaaaaact atgttcttct
    38761 agtaccagtt aacgcagaag aagacgaaga cggacaagtt gaaatccaag cttactcatt
    38821 catcgaaaac gaagatggaa cagaaggcga attgcaacca atcccagaag actcagaaga
    38881 cgaatggaac atgattgaag aagtcttcaa cagctttatg gaggagtgat acagtctggg
    38941 agactgtatc agcccaactc ccagaaatgg ggaagagttg gaacgtccag tgaacatttt
    39001 taccccaact cccagaaatg gggaagagtt ggaacgtcca gtggatgttt ttagcccata
    39061 ttcacattca tagtagctag ttattagcta accaggtaag aggtcgggac gaaaatcctg
    39121 gccttgtttt tattagtaac catactttaa tgcgataatt gattggactt ttgtcaagga
    39181 gatgtgtatg tttgaagtag aagaatggct ccatagtcgg attggtttga attttcgatc
    39241 aggtttgggt cgaatgcagc aagcggtgga tttgttagga aatcctgagc agtcttaccc
    39301 tattatccac gtaacaggga ctaatgggaa aggatctacc attgctttta tgagggaatt
    39361 atttatgggg catggcaaaa aagttgcgac ctttacctcc cctcatatcg tctctatcaa
    39421 tgaccgaatc tgcattaatg ggcagcctat agcagacgca gactttatcc gtttgactga
    39481 tcaggtcaag gagatggaga aaacgcttct gcaaactcct gcccagttgt ccttttttga
    39541 attgctgacc ttggttgctt ttctttattt tagggagcag gaggtggatt tggttttatt
    39601 agaagtggga attggtggct tacttgacac gaccaatgtg gtaactggag agtttgctgt
    39661 catcacctcc attgggcttg accatcaaga aaccttgggt gatagtctag aagcaattgc
    39721 agagcagaaa gctggtattt tcaaggctgg taagaaggca gtgattgcga aattgcctcc
    39781 agaagctagg cttgcctgtc agaaaaaagc cgaatcttta gctgttaacc tttatcaggc
    39841 aggtcaagat tttttaatgc tgaatggtga tttttcaagc tctttactaa atctttcaca
    39901 gctgaacata ggcttagaag gagtctatca gcaggagaat gcagccttgg cgttgcaaac
    39961 ttttcttctt tttatgagag aaagaaagga agctgttgat gaacaggctg taagaaaggc
    40021 cttggaacag acccattggg ctggtcgctt ggagcgtatt cgcccacaga tttatttgga
    40081 tggtgctcat aacctccctg ccttgactcg cttggctgag tttatcaaag aaaaagagca
    40141 ggaaggctat cgacctcaaa tcctctttgg atccttgaaa cgtaaggatt atcaagggat
    40201 gttgggttat ctgactgaaa aattgcctca ggtggaactc aaggtgaccg gctttgacta
    40261 tcagggggct ttggacgaaa gggatgtgac aggttacgat atagtttctt cttaccgaga
    40321 atttatcagc gattttgaag aaagggcaga cgctcaagac ttgctgttcg ttacagggtc
    40381 tctctatttt atctcagaag tacggggcta cctgctggac cgtgagcaga taaattgact
    40441 ccattttttg aacttgttat actaggggaa ttgctggtta gagaaaattt ctctaaattg
    40501 gtagcagaaa ggaaattcat catgaaatta aaaagattca cactttctct tgcttctcta
    40561 gcaagtttta gtctcttagt agcttgttca caaagagctc aacaggttca acagcctgtt
    40621 gctcagcagc aggtccaaca acctgctcaa cagaatacca atactgcaaa tgcaggaggt
    40681 aaccaaaatc aagcggctcc agtacaaaac caacctgttg ctcaaccgac cgatattgat
    40741 gggacttata ctggtcagga tgacggagac cgtatcactt tagtggtaac tggaacgact
    40801 ggtacatgga ctgagctcga atctgacggg gatcagaaag tcaaacaggt tacattggat
    40861 tcagcaaatc aacgcatgat tattggcgat gatgtcaaaa tttacactgt aaacggtaat
    40921 caaatcgtcg tagatgatat ggatagagac ccatcggacc aaatcgtttt aactaaataa
    40981 gactatgcaa gtagaaaggg ctggattttt cagccttttt acttttacct agaaaataat
    41041 cataaatact tgccttctac cgaatacctg cgttatacta gtatcaatta cttgttttta
    41101 gcattcaaac tatcaaggag gggatatgaa atataggaaa tttcaattat tgatgtccaa
    41161 gtatggcttt agtctttcga ttatgctact tgaactttgt cttgtttttg gtctctttct
    41221 ttatttagga cgcatggctc ccattttatg gattactgtc ctcattctac tgagtatcat
    41281 cacaatcatt tcgatagtca accgtaatac gactcctgag aataaggtaa cctggttgtt
    41341 agtagccttt gtgccagtat ttggtccctt gctctatctg atgtttggtg aaaggcgatt
    41401 gtccaaaaaa gaaatcaaac aactgaagaa gctaggctct atgcatttcc aagaagcaaa
    41461 tagccagcta ctaaaagaga aattaaaaga aagtgacaag gcagcttatg gagtcatcaa
    41521 gtccttattg agtatggata ccaatgctga catctatgat caaactgcct ctacattttt
    41581 tcctaacgga gaagctatgt ggaaaaagat ggtagaagat cttaaaaagg ctgagaaatt
    41641 tattttcttg gaatattaca ttatagaaga aggtttgatg tggaatcgca tactagatat
    41701 actagagcaa aaggtagctc agggtgtaga ggttaagatg ctctatgatg atatcggctg
    41761 tatggctact ttaacaggag attatgcaca tcgacttcgt cagctgggca tcgaggccca
    41821 taaattcaat aaagttattc ctcgtttgac agtggcttat aataacagag atcatagaaa
    41881 aatattgatt gttgatggtc agatagccta tactggtggg gtcaatctgg cagatgagta
    41941 cattaaccac gtcgagagat ttggttattg gaaggatagt ggaattcgct tagacggact
    42001 agcagtaaaa gctctgacac gcttattttt gaccacttgg tacattaatc gaggagaaat
    42061 tagtgatttt gatcaatatc atttagaaaa tcattctatc ccgagtgacg gtttaaccat
    42121 tccatacgga agtggaccca agccaatttt tcgagcgcag gtagggaaaa aagtttatca
    42181 gagtttaatc aatcaagcaa cagaatcggt ctatattacg acaccttatt tgattataga
    42241 ttatgattta acagagacaa tcaaaaatgc agctatgaga ggggtcgatg ttcgaattat
    42301 caccccttac ataccagata agaagttcat tcagttagtc acgagaggag cttatcccga
    42361 ccttctttct gctggtgttc ggatttatga gtatagtcca ggttttattc atagtaagca
    42421 gatgttggta gacgaagatt ttgcggtggt ggggacaatc aatctcgact accggagctt
    42481 ggtacaccat tatgaaaatg cagtcttact ctataaaact ccttctataa gggaaatcgc
    42541 ccgagatttt cgaaatatat ttgcagattc tcaggaagtc tatcctcatt ctatcaaaac
    42601 gagctggtat caaaagcttg taaaagaaat cgcccagcta ttcgccccta tcttataaga
    42661 aatctaggac ttaggataca aaccagacct atttttcttg tcttttacga atagaaagaa
    42721 agaggagggg aattcatgct aactaaggaa gaagtgaatg atatgattga gttcaaacag
    42781 acacatttac accgctttcg ggaaattgaa acctttgtga aactatgcaa aaaatcactc
    42841 aaacagccat cgcaagctga caatcctagg actttttgat atactaagac agataaattg
    42901 aacaggagaa acgatatgag tgtgtatggt agagtagaag aagttcataa ggagaatcgt
    42961 gaacctctag aataccaaat cgaacaagaa tcgcatcatc gtgaatcaag tcgtcttcct
    43021 ttggtgaaaa ttttactatg gagtacgctt gtaacgggga taactctagg agtaccgcta
    43081 ttactcgact taatgagtgc acaagaagtg caggattttt atgcaggttg ggcgcttcat
    43141 cagacaggga agatttacag cgactattat ggaagtcaag gtttgcttta ttatttgctg
    43201 acttacgtga gtcagggcgg atttttcttt gccatctttg agtggttagc cttggtagca
    43261 ggaggatttt tcctttttag atcagcggac accttgacag agcaaggaga ccaagctgga
    43321 catctggtga ctatttttta catgctagtt acaggtcttg cttttggtgg aggctatgcg
    43381 actcttttag cgcttccttt cttattcgca gcctttagtt tagttgcggc ttacctaagc
    43441 aatccaagcc atgataaggg atttgtacgg attgggctag ctttggcagg cggatttttc
    43501 tttgctccct tatcatcgct cctgtttatt gctgtagtga gtttaggctt gttggtcttt
    43561 aaccttgggc atagacgctt tgcgcatggg ttttatcagt ttcttgcagt ggctttaggt
    43621 ttttcacttg tcttttatcc aactgcctac tatagtgctg caacaggaag ttttggggat
    43681 gcgattagtg gtattcgtta tcctattgac agtattcgct ttgattttac ttctaaaatt
    43741 ttagagaata tgttttttta tggcttgttg tcccttggtt tgggatttgt ggtttgtatc
    43801 tttttaggtc tctttcaatc caaacccttt aaactatacg tcatttcggt tcctgcaagt
    43861 cttgtggtaa ttttaggttt gattttactt ttcttttcac aagagcctct gcacgcttct
    43921 tatttgatgg tcgtcttccc tgttttccta cttttattgg taaccaatat taagagtcaa
    43981 cagagggggc gtagtgctag aagaagccga agagaaacgc cagttagcct atggagtcgt
    44041 ttcttcaaag gaaatctata tctgctagtt tttgggtttg tctatctttt gtctgttcct
    44101 tttttgatga agtttgtcct ttatccagta ccttatcaag aacgtaatcg tcttgctgat
    44161 ttggtaaaag aggagacaaa tacggaagat gctatctatg catgggatga tactgcgact
    44221 ctttatcgta agagtgagcg cttgtcgcca tcggcgattt tgtccccgtt gcactataca
    44281 gcaactgagg aaaatcgtaa taagttactt aatgacttga aagaaaaaca acctaaggtg
    44341 attgtggtaa atgataaggt ggtagtctgg tctgaagtgg aaacactctt aaaagaaaat
    44401 taccaacaag taaagactga ttactcagag tttaaagtct ataaaattaa ataaccaaat
    44461 caatatcttg tgtattttta aaaattttag gatttttaac acaagatatt gatttttctt
    44521 tttagagtgg tataatactt tttagaaaga acattttaga aaagagcatg catatgattg
    44581 cactagaaga aaaaattaca attttgccaa ctctcttcgt cgagaaacga gatgggagac
    44641 gtgttgtatt tgatgtggac aagattgaca aggctctcca caaggcggct gacaaggtta
    44701 tggatgtgac acccctggtt gaaaaatgcc tcaatgatct gactgagcga attattacag
    44761 aaattcatag tcgctttcca cagggaatta agatttacga aattcaaaat atcgtagaac
    44821 atgaactcct tgaagccaaa gaatatgcgc tggctgagga gtatattact tatcggacac
    44881 agagggattt tgagcgctca aaagcgacgg atatcaactt tagtattcat aaacttctca
    44941 acaaagacca gacagttgtc aatgaaaacg ctaataaaga cagtgatgtc tttaacactc
    45001 agcgtgattt gacagcaggg attgttggga aatcaatcgg actgcaaatg cttcctaagc
    45061 acgtagccaa tgcccaccaa aagggggata tccactatca cgatttggac tacagtccct
    45121 atacccctat gaccaactgc tgtttgattg attttaaggg tatgttggaa aatggtttta
    45181 agattggaaa tgcagaggta gagagtccca agtctatcca gactgcgaca gcacagattt
    45241 ctcaaatcat tgccaacgtt gcttctagcc agtacggtgg ctgttcagct gaccgtatcg
    45301 atgaaatttt ggcgccttat gcagagaaga attatcaaaa acatctcaaa gatgcagaag
    45361 agtgggtatt gcctgaaaaa caggaagatt acgcttggaa gaaagcgcaa aaggacatct
    45421 acgatgccat gcaatctctt gagtatgaaa tcaatactct cttcacttca aatggacaaa
    45481 caccttttac ttcgttaggt tttggtctgg gaaccagtcg ttttgaacga gaaattcaaa
    45541 aagctatttt aaacattcgc atcaagggtc ttggttcaga acaccgtacg gctatctttc
    45601 ctaaacttat ctttacgctt aaaagaggcc tcaacttaga ggaaggaact cccaactatg
    45661 acatcaagca gttggctcta gagtgtgcaa ccaagcggat gtatccagac gtcttgtctt
    45721 atgataagat tgttgatttg acaggttctt tcaaggtgcc tatgggctgc cgttctttcc
    45781 ttcaagggtg gaaggatgaa aatggtgtag aagtcaattc aggtcgcatg aatctgggtg
    45841 ttgtgacggt taatctgcct cgtattgctc ttgagtctga aggtgatatg aataagttct
    45901 gggaaatctt caacgagcga atgaatatcg cagaagatgc tcttgtttac cgtgtcgaac
    45961 gcactaaaga ggcgacacca gcgaatgctc ctattcttta tcagtacggt gcttttggcc
    46021 atcgtctagg taaagaagaa agtgttgacc agctctttaa gaatcgtcgt gcgaccgttt
    46081 cgctgggcta tatcggcttg tatgaagtag cgacagtttt ctttggtaac agctgggaaa
    46141 gtaatccaga tgctaaggaa ttcacgctag acatcattca cgatatgaaa cgccgtgtag
    46201 aagagtggtc agaccaatat ggctaccatt tctctatcta ctcaacacca tccgaaagtc
    46261 tgacagaccg tttctgccga ctagatatag acaagtttgg ctctattcct gatatcacag
    46321 acaaggaata ctacaccaac tctttccact acgatgttcg taaaaatcca acaccgtttg
    46381 aaaaattgga ctttgagaaa gtctatccgg aagcaggtgc gtcaggtggt ttcatccatt
    46441 attgtgagta tccagtcctt cagcaaaatc caaaggcctt ggaagctgtc tgggattatg
    46501 cttatgaccg tgtaggctat ctaggcacca atactccgat tgaccgttgc tacaagtgtg
    46561 actttgaagg ggattttgaa ccaactgaga gagggtttgc ttgtccaaac tgtggcaata
    46621 gcgaccctaa aacagtagat gtggtgaaac gaacttgtgg ctacctaggt aatcctcaag
    46681 caagaccgat ggtcaacggg cgtcacaagg aaatcgctgc gcgtgtcaaa catatgaatg
    46741 gttcaacgat taaaatagct gggcatcaag taacaaatta gaaagaaatg aaatgggaaa
    46801 atatcaacta gacgataagg ggcgcgcaca agtgacccgt tatcacgaga aacactctaa
    46861 aggtggagct ggtaagaaag aacgcttgct tagcttcaga gaacaatttt taaacaagaa
    46921 caagaaaaaa taaaagtgag agccagctct cgcttttctc atagtgggag gtaaggatgg
    46981 aattacgcag accaagatta gcggataaga aagctgtttt agatatgatg acagagtttg
    47041 aaaaatttca gtcgcctcac gacggcggtt tctgggatac agagaacttt gtgtatgaag
    47101 actggttaga aagcaatcag gaacaggaaa tggggattaa tctgcctgaa ggatgggttt
    47161 ctgcaattca gttagtggct ttttctgaga aaggtcaagc agttggattt cttaatctcc
    47221 ggttgcgcct cagtaacttt ctactagaag aaggtggcca cattggctac tccattcgtc
    47281 catctgaaag aggcaagggt tatgcaaaag agactctccg tcagggcttg caagttgcta
    47341 aggaaaagaa catcaagaaa gctctggtga cctgtagtgt gaataatcct gctagcagag
    47401 cagtcattct agcaaatggt ggaatatttg aggatgctcg caatggagtc gagcgttatt
    47461 ggatagaggt agcgaatgaa taatccaaaa ccacaagaat ggaaaagcga ggaacttagt
    47521 caaggtcgta tcattgacta caaggccttt aactttgtgg acggcgaagg cgtgcgcaac
    47581 tctctctatg tatcaggctg tatgtttcac tgcgagggat gttataatgt tgcgacttgg
    47641 tcttttaatg ctggcattcc ctatacagca gaattagaag agcagattat ggcagacctt
    47701 gcccaaccct atgttcaagg cttgactttg ctgggagggg agccttttct caatactggg
    47761 attctcttgc cacttgttaa gcggattcgg aaggaattgc cagacaagga catctggtcc
    47821 tggaccggct acacttggga agaaatgatg ttggaaactc cagataaact ggaattcttg
    47881 tcactgattg acattcttgt cgatggaaga tatgatcgaa ctaagagaaa tcttatgctc
    47941 cagtttcgag gttcatctaa ccaacgaatt atcgatgtgc aaaaatcgct caaaagtggg
    48001 caagtagtga tttgggacaa gctcaatgac ggaaaagaaa gctatgaaca ggtgaagaga
    48061 gaatgaagaa aaaggactta gtagaccaac tagtctcaga gatcgagacg gggaaagtca
    48121 ggacactggg aatatacggt catggagctt caggtaaatc aacctttgca caggaattgt
    48181 accaagcttt agattctact acagtaaatt tgctagagac agatccttat atcacctcag
    48241 gacgccatct ggtagtaccc aaggacgcgc cgaatcaaaa ggtgacagcc agtctgccag
    48301 tggcgcatga actggagagt ttgcagagag atatccttgc cttgcaggcg ggtatggatg
    48361 tcttgacaat tgaagaacct tggaaggcta gtgaggtctt gtctggagcc aaaccaattt
    48421 tgattgtcga agggatgtct gttggctttc tacccaagga actctttgaa aaaaccatct
    48481 gtttctacac ggatgaggag accgaattaa agcgacgcct tgctagagat acgactgtga
    48541 gaaatcgcga tgcatccttt atattggcta gccatcagat gagacgggag cagtatctgc
    48601 gatactataa agaaactgag tctaaggcgg atatcttagt ggaccaatca gaagataaat
    48661 ttgatgtcaa gaggacttaa cttatgtata gaagaaatat agaagaaaat ccctaatttt
    48721 agaaagaaaa agtaggaaaa cagtttcatc ccaaaaaaac gaaaaaacag caacaaatcc
    48781 cttgcaatcg caggggcttt gtgttattct attatggtgc tgtaaattac agccttagtt
    48841 ttgatgcaag aggttgcgac acgctcggtt gcattgccac gcaacaccgc gtcggttttc
    48901 ttgtggagct agcctattat cttaaataga cgaaaaggag aaaaagatgg caaacaaaaa
    48961 aatccgtatc cgtttgaaag cttacgaaca ccgtacgctt gacacagcgg ctgcaaaaat
    49021 cgtagaatca gctactcgta caggtgcaca agttgcgggt ccaatcccac ttccaactga
    49081 acgtagcctc tacacaatca ttcgtgcgac tcacaaatac aaagactctc gcgaacaatt
    49141 tgaaatgcgt acacacaaac gtttgatcga tatcgttaac ccaactcaaa aaacagttga
    49201 tgccttgatg aaattggatc ttccaagtgg tgtaaacgta gaaatcaaac tttaatctaa
    49261 aatataaaag agcagaggct ggtgtttcaa tctaattgaa cacgggctaa actcggtgtg
    49321 aaaaagataa acttcctagt gtctgctaga cactgcgtca gtttcctatt ttcacgttga
    49381 gtttgacgcc ctttgtatct tagacttgag cataaaaaac gctcgttaaa aactttttga
    49441 ataaaaaata tagaaaagga actattttct catgacaaaa ggaatcttag ggaaaaaagt
    49501 gggaatgact caaatcttca ctgaagctgg cgaattgatc cctgtaacag ttattgaagc
    49561 aactccaaac gttgttcttc aagttaaaac tgttgaaaca gacggataca acgctatcca
    49621 agttggtttc gatgacaaac gcgaagtatt gagcaacaaa cctgctaaag gacatgtagc
    49681 gaaagctaac acggctccta agcgcttcat tcgtgaattc aaaaacgttg aaggcttgga
    49741 agttggtgct gaaattacag ttgaaacatt cgcagctgga gacgttgttg acgtaacggg
    49801 tacttctaaa ggtaaaggtt tccaaggtgt tatcaaacgc cacggacaat cacgtggacc
    49861 aatggctcac ggttctcgtt accaccgtcg tccaggttct atggggcctg ttgcacctaa
    49921 ccgcgtattc aaaggtaaaa accttgcagg acgtatgggt ggcgaccgcg taacaattca
    49981 aaaccttgaa gttgtacaag ttgttccaga aaagaacgtt atccttatca aaggtaacgt
    50041 accaggtgct aagaaatctc ttatcactat caaatcagca gttaaagctg gtaaataata
    50101 aagaaagggg aaatcagtca caatggcaaa cgtaacatta tttgaccaaa ctggtaaaga
    50161 agctggccaa gttgttctta gcgatgcagt atttggtatc gaaccaaatg aatcagttgt
    50221 gtttgatgta atcatcagcc aacgcgcaag ccttcgtcaa ggaacacacg ctgttaaaaa
    50281 ccgctctgca gtatcaggtg gtggacgcaa accatggcgt caaaaaggaa ctggacgtgc
    50341 tcgtcaaggt tctatccgct caccacaatg gcgtggtggt ggtgttgtct tcggaccaac
    50401 tccacgttca tacggctaca aacttccaca aaaagttcgt cgcctagctc ttaaatcagt
    50461 ttactctgaa aaagttgctg aaaacaaatt cgtagctgta gacgctcttt catttacagc
    50521 tccaaaaact gctgaatttg caaaagttct tgcagcattg agcatcgatt ctaaagttct
    50581 tgttatcctt gaagaaggaa atgaattcgc agctctttca gctcgtaacc ttccaaacgt
    50641 gaaagttgca actgctacaa ctgcaagtgt tcttgacatc gcaaatagcg acaaacttct
    50701 tgtcacacaa gcagctatct ctaaaatcga ggaggttctt gcataatgaa tttgtatgat
    50761 gttatcaaaa aacctgtcat cactgaaagc tcaatggctc aacttgaagc aggaaaatat
    50821 gtatttgaag ttgacactcg tgcacacaaa cttttgatca agcaagctgt tgaagctgct
    50881 ttcgaaggtg ttaaagttgc caatgttaac acaatcaacg taaaaccaaa agctaaacgt
    50941 gttggacgtt acactggttt tactaacaaa actaaaaaag ctatcatcac acttacagct
    51001 gattctaaag caatcgagtt gtttgctgct gaagctgaat aatctaagga ggaaatatcg
    51061 tgggaattcg tgtttataaa ccaacaacaa acggtcgccg taatatgact tctttggatt
    51121 tcgctgaaat cacaacaagc actcctgaaa aatcattgct tgttgcattg aagagcaagg
    51181 ctggtcgtaa caacaacggt cgtatcacag ttcgtcacca aggtggtgga cacaaacgtt
    51241 tctaccgttt ggttgacttc aaacgtaata aagacaacgt tgaagcagtt gttaaaacaa
    51301 tcgagtacga tccaaaccgt tctgcaaaca tcgctcttgt acactacact gacggtgtga
    51361 aagcatacat catcgctcca aaaggtcttg aagtaggtca acgtatcgtt tcaggtccag
    51421 aagcagatat caaagtcgga aacgctcttc cacttgctaa catcccagtt ggtactttga
    51481 ttcacaacat cgagttgaaa ccaggtcgtg gtggtgaatt ggtacgtgct gctggtgcat
    51541 ctgctcaagt attgggttct gaaggtaaat atgttcttgt tcgtcttcaa tcaggtgaag
    51601 ttcgtatgat tcttggaact tgccgtgcta cagttggtgt tgtcggaaac gaacaacatg
    51661 gacttgtaaa ccttggtaaa gcaggacgta gccgttggaa aggtatccgc ccaacagttc
    51721 gtggttctgt aatgaaccct aacgatcacc cacacggtgg tggtgaaggt aaagcaccag
    51781 ttggtcgtaa agcaccatct actccatggg gcaaacctgc tcttggtctt aaaactcgta
    51841 acaagaaagc gaaatctgac aaacttatcg ttcgtcgtcg caacgagaaa taatattaaa
    51901 ctagtcgctt aagcaactag taaatccgcc agctcggtag cgctccatag gagtgcaagc
    51961 cgctgtggta caacatttaa aggagaaaat ataaaaatgg gacgcagtct taaaaaagga
    52021 cctttcgtcg atgagcattt gatgaaaaaa gttgaagctc aagctaacga cgaaaagaaa
    52081 aaagttatta aaacttggtc acgtcgttca acgatcttcc caagtttcat tggttacact
    52141 attgcagttt atgacggacg taaacacgta cctgtttaca tccaagaaga catggtaggc
    52201 cacaaacttg gtgaatttgc accaactcgt acttacaaag gtcacgctgc agacgacaag
    52261 aaaacacgta gaaaataagg agaacataaa tggcagaaat tacttcagct aaagcaatgg
    52321 ctcgtacagt acgtgtttca cctcgtaaat cacgtcttgt tcttgataac atccgtggta
    52381 aaagcgtagc cgatgcaatc gcaatcttga cattcactcc aaacaaagct gctgaaatca
    52441 tcttgaaagt tttgaactca gctgtagcta acgctgaaaa caactttggt ttggataaag
    52501 ctaacttggt agtatctgaa gcattcgcaa acgaaggacc aactatgaaa cgtttccgtc
    52561 cacgtgcgaa aggttcagct tcaccaatca acaaacgtac agctcacatc actgtagctg
    52621 ttgcagaaaa ataaggaggt aaaatcgtgg gtcaaaaagt acatccaatt ggtatgcgtg
    52681 tcggcatcat ccgtgattgg gatgccaaat ggtatgctga aaaagaatac gcggattacc
    52741 ttcatgaaga tcttgcaatc cgtaaattcg ttcaaaaaga acttgctgac gcagcagttt
    52801 caactattga aatcgaacgc gcagtaaaca aagttaacgt ttcacttcac actgctaaac
    52861 caggtatggt tatcggtaaa ggtggtgcta acgttgatgc actccgtgca aaacttaaca
    52921 aattgactgg aaaacaagta cacatcaaca tcatcgaaat caaacaacct gatttggatg
    52981 ctcaccttgt aggtgaagga attgctcgtc aattggagca acgtgttgct ttccgtcgtg
    53041 cacaaaaaca agcaatccaa cgtgcaatgc gtgctggagc taaaggaatc aaaactcaag
    53101 tatcaggtcg tttgaacggt gcagatatcg cccgtgctga aggatactct gaaggaactg
    53161 ttccgcttca cacacttcgt gcagatatcg attacgcttg ggaagaagca gatactacat
    53221 acggtaaact tggtgttaaa gtatggatct accgtggtga agttcttcca gctcgtaaaa
    53281 acactaaagg aggtaaataa ccaatgttag tacctaaacg tgttaaacac cgtcgtgagt
    53341 tccgtggaaa aatgcgcggt gaagcaaaag gtggaaaaga agtagcattc ggtgaatacg
    53401 gtcttcaagc tacaactagc cactggatca ctaaccgcca aatcgaagct gctcgtatcg
    53461 ccatgactcg ttacatgaaa cgtggtggta aagtttggat taaaatcttc ccacacaaat
    53521 catacactgc taaagctatc ggtgtgcgta tgggatctgg taaaggggca cctgaaggtt
    53581 gggtagcacc agttaaacgt ggtaaagtga tgttcgaaat cgctggtgta tctgaagaga
    53641 ttgcacgtga agcgcttcga cttgctagcc acaaattgcc agttaaatgt aaattcgtaa
    53701 aacgtgaagc agaataagga gaaggcatga aacttaatga agtaaaagaa tttgttaaag
    53761 aacttcgtgg tctttctcaa gaagaactcg cgaagcgcga aaacgaattg aaaaaagaat
    53821 tgtttgaact tcgtttccaa gctgctactg gtcaattgga acaaacagct cgcttgaaag
    53881 aagttaaaaa acaaatcgct cgcatcaaaa cagttcaatc tgaagcgaaa taatagacta
    53941 gggaaggaga aatttcaatg gaacgcaata atcgtaaagt tcttgttgga cgtgttgtat
    54001 ctgacaaaat ggacaagaca atcacagttg tagttgaaac aaaacgtaac cacccagtct
    54061 atggtaaacg tattaactac tctaaaaaat acaaagctca tgatgaaaac aatgttgcca
    54121 aagaaggcga tatcgtacgt atcatggaaa ctcgcccgct ttcagctaca aaacgtttcc
    54181 gtcttgtaga agttgttgaa gaagcggtca tcatctaatc aaacctgaaa ggagaaaact
    54241 gaaatgattc aaacagaaac tcgtttgaaa gtcgcagaca acagcggtgc tcgcgaaatc
    54301 ttgactatca aagttcttgg tggttcagga cgtaaatttg caaacatcgg tgatgttatc
    54361 gtggcatctg taaaacaagc tactcctggt ggtgcggtta aaaaaggtga cgttgttaaa
    54421 gcagttatcg ttcgtactaa atcaggtgct cgtcgtgctg atggttcata catcaaattt
    54481 gacgaaaacg cagcagttat catccgtgaa gacaaaactc ctcgcggaac acgtatcttt
    54541 ggcccagttg cacgtgaatt gcgtgaaggt ggcttcatga agatcgtgtc acttgctcca
    54601 gaagtacttt aatttttagg aacaaactag tcccctagct tcaagctagg gtgcccttat
    54661 gggcgtaaga aaaatcaagg agaaacctaa tgtttgtaaa aaaaggcgac aaagttcgcg
    54721 taatcgctgg taaagataag ggaacagaag ctgttgtcct tactgccctt ccaaaagtaa
    54781 acaaagttat cgttgaaggt gttaacattg ttaagaaaca ccaacgtcca actaacgagc
    54841 ttcctcaagg tggtatcatc gagaaagaag cagctatcca cgtatcaaac gttcaagttt
    54901 tggacaaaaa tggtgtagct ggtcgtgttg gatacaaatt tgtagacggt aaaaaagttc
    54961 gctacaacaa aaaatcaggc gaagtgcttg attaatcacg aaggaaagga gaagtataat
    55021 ggcaaatcgt ttaaaagaaa aatatcttaa tgaagtagtt cctgctttga cagaacaatt
    55081 caactactca tcagtgatgg ctgtgcctaa agtagataag attgttttga acatgggtgt
    55141 tggtgaagct gtatcaaacg ctaaaagcct tgaaaaagct gctgaagaat tggcacttat
    55201 ctcaggtcaa aaaccactta tcactaaagc taaaaaatca atcgccggct tccgtcttcg
    55261 tgaaggtgtt gcgatcggtg caaaagttac ccttcgtggt gaacgtatgt acgaattctt
    55321 ggataaattg gtatcagttt cacttccacg tgtacgtgac ttccacggtg tcccaacaaa
    55381 atcatttgat ggacgcggga actacacact tggtgtgaaa gaacaattaa tcttcccaga
    55441 aatcaacttc gatgacgttg acaaaactcg tggtcttgac atcgttatcg taacaactgc
    55501 taacactgac gaagagtcac gtgcattgct tacaggcctt ggaatgcctt ttgcaaaata
    55561 atataggagg taaatctaat ggctaaaaaa tcaatggtag ctagagaggc taaacgccaa
    55621 aaaattgttg accgttatgc tgaaaaacgt gctgcattaa aggcggcagg ggactacgaa
    55681 ggtttatcta aattacctcg caacgcctca ccgactcgtt tacataatcg ttgtagggtt
    55741 acggggcgcc cacattcagt ttaccgcaaa tttggtctga gtcgtatcgc ttttcgcgaa
    55801 cttgcgcata aaggtcaaat tcctggtgta acaaaagcat cttggtaatt taagatatca
    55861 agagcgtcaa aactccaagt aaaaatagga aacttgacga agaaactaaa gtttctagga
    55921 aagtttatct ttttcacaca gagtttagcc cgggttcaat tgggcttgcc aatttgaaca
    55981 cgagctacag ctttggcaaa aaagaccaat ttgctttgga gcattgcttc tgcattaaat
    56041 tgtctatttt tgctcgtgct gttacgctct ttgtatcatg tattaactag caagtgcaac
    56101 ttgcaaacta ctagtaagag gagaaaaaca aaatggttat gactgaccca atcgcagact
    56161 tcctaactcg tattcgtaat gctaaccaag ctaaacacga agtacttgaa gtacctgcat
    56221 caaacatcaa aaaagggatt gctgaaatcc ttaaacgcga aggttttgta aaaaacgttg
    56281 aaatcattga agatgacaaa caaggcgtca tccgtgtatt tcttaaatac ggaccaaatg
    56341 gtgagaaagt tatcactaac ttgaaacgtg tttctaaacc aggacttcgt gtctacaaaa
    56401 aacgtgaaga ccttccaaaa gttcttaacg gacttggaat tgccatcctt tcaacttctg
    56461 aaggtttgct tactgataaa gaagcacgcc aaaagaatgt tggtggtgag gttatcgctt
    56521 acgtttggta aaatcaagat acaaagctcg taaagaacaa agcaaaatta ggaagttgga
    56581 gaagtttgtt tacaaacaag ccaacttatc tattttgcac agttcttaga gcgtgttcag
    56641 ttcagctctt gaactaaata agtatctgaa ccccgtgaaa actggccgtt ctggcctgac
    56701 aatttaacag gagaaaataa acatgtcacg tattggtaat aaagttatcg tgttgcctgc
    56761 tggtgttgaa ctcgctaaca atgacaacgt tgtaactgta aaaggatcta aaggagaact
    56821 tactcgtgag ttctcaaaag atattgaaat ccgtgtggaa ggtactgaaa taactcttca
    56881 ccgtccaaac gattcaaaag aaatgaaaac tatccacgga actactcgtg cccttttgaa
    56941 caacatggtt gttggtgtat cagaaggatt caagaaagaa cttgaaatgc gtggggttgg
    57001 ttaccgtgca cagcttcaag gatctaaact tgttttggct gttggtaaat ctcatccaga
    57061 cgaagttgaa gctccagaag gaattacttt tgaacttcca aacccaacaa caatcgttgt
    57121 tagcggaatt tcaaaagaag tagttggtca aacagctgct tacgtacgta gccttcgttc
    57181 accagaacca tataaaggta aaggtatccg ttacgttggt gaattcgttc gccgtaaaga
    57241 aggtaaaaca ggtaaataat gttgagtggt tgatcatcaa ccaccaacct attttccaac
    57301 tttgtgcata gcacacgatt taaaactaaa gaggtgaaaa ctgtgatttc aaaaccagat
    57361 aaaaacaaac tccgccaaaa acgccaccgt cgcgttcgcg gaaaactctc tggaactgct
    57421 gatcgcccac gtttgaacgt attccgttct aatacaggca tctacgctca agtgattgat
    57481 gacgtagcgg gtgtaacgct cgcaagtgct tcaactcttg ataaagaagt ttcaaaagga
    57541 actaaaactg aacaagccgt tgctgtcggt aaactcgttg cagaacgtgc aaacgctaaa
    57601 ggtatttcag aagtggtgtt cgaccgcggt ggatatctat atcacggacg tgtgaaagct
    57661 ttggctgatg cagctcgtga aaacggattg aaattctaat aggaggacac tagaaaatgg
    57721 catttaaaga caatgcagtt gaattagaag aacgcgtagt tgctgtcaac cgtgttacaa
    57781 aagttgttaa aggtggacgt cgtcttcgtt tcgcagctct tgttgttgtt ggtgaccaca
    57841 atggtcgcgt aggatttggt actggtaaag ctcaagaagt tccagaagca atccgtaaag
    57901 cagtagatga tgctaagaaa aacttgatcg aagttcctat ggttggaaca acaatcccac
    57961 acgaagttct ttcagaattc ggtggagcta aagtattgtt gaaacctgct gtagaaggtt
    58021 ctggagttgc cgctggtggt gcagttcgtg ccgttgtgga attggcaggt gtggcagata
    58081 ttacatctaa atcacttggt tctaacactc caatcaacat tgttcgtgca actgttgaag
    58141 gtttgaaaca attgaaacgc gctgaagaaa ttgctgccct tcgtggtatt tcagtttctg
    58201 atttggcata agaaagggga taaaatggct caaattaaaa ttactttgac taagtctcca
    58261 atcggacgca ttccatcaca acgtaaaact gttgtagcac ttggacttgg caaattgaac
    58321 agctctgtta ttaaagaaga taacgctgct atccgtggta tgatcacagc agtatctcac
    58381 ttagtaacag ttgaagaagt aaactaatga agttttaggg gatgtgcact gtaccatccc
    58441 ctaaaactag atatagtcat ctatgatgac atcgtatagg cgagttgatg ggggagacaa
    58501 ccttttctcc cttatcggcg ctagcatttt acaaaagagg agaaaataaa aatgaaactt
    58561 catgaattga aacctgcaga aggttctcgt aaagtacgta accgcgttgg tcgtggtact
    58621 tcatcaggta acggtaaaac atctggtcgt ggtcaaaaag gtcaaaaagc tcgtagcggt
    58681 ggcggagttc gccttggttt tgaaggtgga caaactccat tgttccgtcg tcttccaaaa
    58741 cgtggattca ctaacatcaa cgctaaagaa tacgcaattg tgaaccttga ccaattgaac
    58801 gtctttgaag atggtgctga agtaactcca gttgttctta tcgaagcagg aattgttaaa
    58861 gctgaaaagt caggtattaa aattcttggt aacggtgagt tgactaagaa attgactgtg
    58921 aaagcagcta aattctctaa atcagctgaa gaagctatca ctgctaaagg tggttcagta
    58981 gaagtcatct aagagaggtg acctatgttt tttaaattat taagagaagc tcttaaagtc
    59041 aagcaggttc gatcaaaaat tttatttaca atttttatcg ttttggtctt tcgtatcgga
    59101 actagcatta cagttcctgg tgtgaatgcc aatagcttga atgctttaag tggattatcc
    59161 ttcttaaaca tgttgagctt ggtgtcgggg aatgccctaa aaaacttttc gatttttgcc
    59221 ctaggagtta gtccctatat caccgcttct attgttgtcc aactcttgca aatggatatt
    59281 ttacccaagt ttgtagagtg gggtaaacaa ggggaagtag gtcgaagaaa attgaatcaa
    59341 gctactcgtt atattgctct agttctcgct tttgtgcaat ctatcgggat tacagctggt
    59401 tttaatacct tggctggagc tcaattgatt aaaactgctt taactccaca agtttttctg
    59461 acgattggta tcatcttaac agctggtagt atgattgtca cttggttggg tgagcaaatt
    59521 acagataagg gatacggaaa cggtgtttcc atgattatct ttgccgggat tgtttcctca
    59581 attccagaga tgattcaggg catctatgtg gactactttg tgaacgtccc aagtagccgt
    59641 atcacttcat ctatcatttt cgtaatcatt ttgattatta ctgtattgtt gattatttac
    59701 tttacaactt atgttcaaca agcagaatac aaaattccaa tccaatatac taaggttgca
    59761 caaggtgctc catctagctc ttaccttccg ttaaaagtaa accctgctgg agttatccct
    59821 gttatctttg ccagttcgat tactgcagcg cctgcggcta ttcttcagtt tttgagtgcc
    59881 acaggtcatg attgggcttg ggtaagggta gcacaagaga tgttggcaac tacttctcca
    59941 actggtattg ccatgtatgc tttgttgatt attctcttta cattcttcta tacgtttgta
    60001 cagattaatc ctgaaaaagc agcagagagc ctacaaaaga gtggtgccta tatccatgga
    60061 gttcgtcctg gtaaaggtac agaagaatat atgtctaaac ttcttcgtcg tcttgcaact
    60121 gttggttccc tcttccttgg tgtgatttcc attttaccga ttgcagctaa agatgtattt
    60181 ggtctttctg atgttgttgc ctttggtgga acaagtctct tgatcattat ctctacaggt
    60241 atcgaaggaa tcaagcaatt ggaaggttac ctattgaaac gtaagtatgt tggtttcatg
    60301 gacagaacag aataaaagta tttactgaat cagtaaatac tgagggagtg gaggtttaaa
    60361 ctctgacatt tgtaagagtt ggatctcccc tcttctattt tgtttttaaa tcggggtgaa
    60421 aagacttttt gcttctattt aaaaataaaa taaggagatc aaatcatgaa tcttttgatt
    60481 atgggcttac ctggtgcagg taagggaact caagcagcaa aaatcgtaga acaattccat
    60541 gttgcacata tctcaacagg tgatatgttc cgcgctgcaa tggcaaatca aactgaaatg
    60601 ggtgttcttg ctaagtcata tattgacaag ggtgaattgg ttcctgacga agttacaaat
    60661 ggaatcgtaa aagaacgcct ttcacaagat gatattaaag aaacaggatt cttattggat
    60721 ggttacccac gtacaattga acaagctcat gccttggaca aaacattggc tgaacttggc
    60781 attgaactag aaggtgttat caatattgaa gtgaaccctg acagcctttt ggaacgtttg
    60841 agtgggcgta tcatccaccg cgtaactgga gaaactttcc acaaggtctt taacccacca
    60901 gttgactata aagaagaaga ttactaccaa cgtgaagatg ataagcctga gacagtaaaa
    60961 cgtcgtttgg atgttaatat tgctcaagga gaaccaatca ttgctcacta ccgtgccaaa
    61021 ggtttggttc atgacatcga aggtaatcaa gatatcaatg atgtcttctc agatattgaa
    61081 aaagtattga caaatttgaa ataaagcgtt tttcacactt gcaaaaatcc gctacaaatg
    61141 ttatactgag atagtctgac ttataattgt tgtctctgtg tctagaggca tcgaatcgaa
    61201 atttatggag gtgcttttgc gtggcaaaag acgatgtgat tgaagttgaa ggcaaagtag
    61261 ttgatacaat gccgaatgca atgtttacgg ttgaacttga aaatggacat cagattttag
    61321 caacagtttc tggtaaaatt cgtaaaaact atattcgtat tttagcggga gatcgtgtta
    61381 ctgtcgaaat gagtccatat gacttgacac gtggacgtat cacttaccgc tttaaataat
    61441 cgaaaaactt ggagggataa gaaatgaaag taagaccatc ggtcaaacca atttgcgaat
    61501 actgtaaagt tattcgtcgt aatggtcgtg ttatggtaat ttgcccagca aatccaaaac
    61561 acaaacaacg tcaaggataa gatagaaagg agaaaacatg gctcgtattg ctggagttga
    61621 tattccaaat gacaaacgcg tagtaatctc attgacttat gtttatggta tcggacttgc
    61681 aacatctaag aaaattttgg ctgctgctgg aatctcagaa gatgttcgtg tacgtgatct
    61741 tacatcagat caagaagatg ctatccgtcg tgaagtggat gcaatcaaag ttgaaggtga
    61801 ccttcgtcgt gaagtaaact tgaacatcaa acgtttgatg gaaatcggtt cataccgtgg
    61861 tatccgtcac cgtcgtggac ttcctgtccg tggacaaaac actaaaaaca acgcccgcac
    61921 tcgtaaaggt aaagctgttg cgattgctgg taagaaaaaa taatatagga ggtaaaagtc
    61981 ttggctaaac caacacgtaa acgtcgtgtg aaaaagaata tcgaatctgg tattgctcat
    62041 attcacgcta catttaataa cactattgtt atgattactg atgtgcatgg taatgcaatt
    62101 gcttggtcat cagctggtgc tcttggtttc aaaggttctc gtaaatctac accattcgct
    62161 gctcaaatgg cttctgaagc tgctgctaaa tctgcacaag aacacggtct taaatcagtt
    62221 gaagttactg taaaaggtcc aggttctggt cgtgagtcag ctattcgtgc gcttgctgcc
    62281 gctggtcttg aagtaacagc aattcgtgat gtgactccag tgccacacaa tggtgctcgt
    62341 cctccaaaac gtcgccgtgt ataatcatcg cattacactg cttttcgttt aagagggagt
    62401 aactaaatga tcgagtttga aaaaccaaat ataacaaaaa ttgatgaaaa taaagattat
    62461 ggcaagtttg taatcgaacc acttgaacgt ggctacggta caactcttgg taactctctt
    62521 cgtcgtgtac ttctagcttc tctaccagga gcagctgtga catctatcaa cattgatggt
    62581 gtgttacatg agtttgacac agttccaggt gttcgtgaag acgtgatgca aatcattctg
    62641 aacattaaag gaattgcagt gaaatcgtac gttgaagacg aaaaaatcat cgaactggat
    62701 gttgaaggtc ctgctgaagt aacagctggt gacattttga cagatagcga tattgaaatt
    62761 gtaaatccag atcattatct ctttacaatc ggtgaaggtt cttctctaaa agcgactatg
    62821 actgttaaca gtggtcgtgg atatgtacct gctgatgaaa ataaaaagga taatgcacca
    62881 gttggaacac ttgctgtaga ttctatttat acaccagtta caaaagtcaa ctatcaagtg
    62941 gaacctgctc gtgtaggtag caatgatggt ttcgacaaat taacccttga aatcttgaca
    63001 aatggaacaa ttattccaga agatgcttta gggctttcag cacgtatttt gacagaacat
    63061 cttgatttgt ttacaaatct tactgagatt gctaagtcaa ctgaagtgat gaaagaagct
    63121 gatactgaat ctgacgaccg tattttagat cgtacgattg aggaactgga cttgtctgtg
    63181 cgttcataca actgtttaaa acgtgccggt atcaatactg tgcatgattt gacagaaaaa
    63241 tctgaagcag agatgatgaa agtacgaaat cttggacgca agagtttgga agaagtgaaa
    63301 ctcaaactca ttgatttggg tcttggatta aaagataaat aaaggaggaa tacatggctt
    63361 accgtaaact aggacgcact agctcacaac gtaaagcaat gcttcgcgat ttgacaactg
    63421 accttttgat caacgaatca atcgtgacaa ctgaagctcg tgctaaagaa atccgtaaaa
    63481 ctgttgaaaa aatgattact ctaggtaaac gtggtgattt gcatgcacgt cgtcaagcag
    63541 ctgctttcgt acgtaatgaa atcgcatctg aaaactatga tgaagcaact gataagtaca
    63601 cttctactac agcacttcaa aaattgttct cagaaatcgc acctcgttat gctgaacgta
    63661 acggtggata cactcgtatc cttaaaactg aatcacgtcg tggtgatgca gcgccaatgg
    63721 cgatcatcga attagtataa aatcatcaat tttgttgagt gttatgatga tggagtcttg
    63781 tgctcttagt ctagctctgg tctaccgcta ggatttcggt cctagcggga acactcatca
    63841 taagttggga tagtagacgc ttgtttacga aattgttttt ttcttaagaa caacttcgta
    63901 agcaggcgtt tttgagtatt ttcgttagaa ttatgctata ctatttgaaa agaatcctgt
    63961 ttaatgttaa ggtttcttat tttaagaaga attggagttt acttatgaaa gccattataa
    64021 ctgttgttgg taaagataaa tctggaattg ttgcaggtgt ttctggtaaa attgcagaat
    64081 taggattgaa tattgacgat atctctcaaa ctgtcttgga tgaatatttt acgatgatgg
    64141 ctgttgtatc tagtgatgaa aagcaagatt ttacctatct tcgtaatgaa tttgaagctt
    64201 ttgggcaaac tttgaatgta aaaatcaata ttcagagtgc agcgattttc gaagctatgt
    64261 ataatatcta ggaggtcatc atggatatta gacaagttac tgaaaccatc gccatgattg
    64321 aggagcaaaa cttcgatatt agaaccatta ccatggggat ttctcttttg gactgtatcg
    64381 atccagatat caatcgtgct gcggagaaaa tctatcaaaa aattacgaca aaggcggcta
    64441 atttagtagc tgttggtgat gaaattgcgg ctgagttggg aattcctatc gttaataagc
    64501 gtgtatcggt gacacctatt tctctgattg gggcagcgac agatgcgacg gactacgtgg
    64561 ttctggcaaa agcgcttgat aaggctgcga aagagattgg tgtggacttt attggtggtt
    64621 tttctgcctt agtacaaaaa ggttatcaaa agggagatga gattctcatc aattccattc
    64681 ctcgcgcttt ggctgagacg gataaggtct gctcgtcagt caatatcggc tcaaccaagt
    64741 ctggtattaa tatgacggct gtggcagata tgggacgaat tatcaaggaa acagcaaatc
    64801 tttcagatat gggagtggcc aagttggttg tattcgctaa tgctgttgag gacaatccat
    64861 ttatggcggg tgcctttcat ggtgttgggg aagcagatgt tatcatcaat gtcggagttt
    64921 ctggtcctgg tgttgtgaaa cgtgctttgg aaaaagttcg tggacagagc tttgatgtag
    64981 tagccgaaac agttaagaaa actgccttta aaatcactcg tatcggtcaa ttggttggtc
    65041 aaatggccag tgagagactg ggtgtggagt ttggtattgt ggacttgagt ttggcaccaa
    65101 cccctgcggt tggagactct gtggcacgtg tccttgagga aatggggcta gaaacagttg
    65161 gcacgcatgg aacgacggct gccttggccc tcttgaacga ccaagttaaa aagggtggag
    65221 tgatggcctg caaccaagtc ggtggtttat ctggtgcctt tatccctgtt tctgaggatg
    65281 aaggaatgat tgctgcagtg caaaatggct ctcttaattt agaaaaacta gaagctatga
    65341 cggctatctg ttctgttgga ttggatatga ttgccatccc agaagatacg cctgctgaaa
    65401 ctattgcggc tatgattgcg gatgaagcag caatcggtgt tatcaacatg aaaacaacag
    65461 ctgttcgtat cattcccaaa ggaaaagaag gcgatatgat tgagtttggt ggtctattag
    65521 gaactgcacc cgttatgaag gttaatgggg cttcgtctgt cgacttcatc tctcgcggtg
    65581 gacaaatccc agcaccaatt catagtttta aaaattaaga aaataggaga aattttaagt
    65641 tctatttaag attagacgtg tatactataa tcattaaata aagacctcct aatattattt
    65701 gaaacagata acactgaatt agtttgaatt tgattttcat ctaatatctt tatttaatga
    65761 actcctaaac tttttcataa taatctcctt caaaagtcgc ctgtatgggt ggcttttatt
    65821 ttatcattca tgatataata gaagcaaacg gaggacggaa aatggtaaaa gtacgattgt
    65881 atttggtacg tcatggcaag accatgttta acacgattgg tcgcgcgcaa ggttggagcg
    65941 atactccctt aactgctgaa ggtgaacgag ggattcaaga gttaggaatc ggtttgcgag
    66001 aatctgatct acagtttgag cgtgcttatt cgagtgattc tggtcgtacc attcagacca
    66061 tgggaattat ccttgaagaa cttggcttgc agggggaaat cccttatcgc atggacaagc
    66121 gtatcagaga atggtgtttc ggtagttttg atggagccta tgatggcgat cttttcatgg
    66181 gcattattcc tcgtatcttt aatgtggacc acgttcacca attgtcttat gctgaactgg
    66241 ctgagggctt ggtagaggtc gatacagctg gttgggctga aggctgggaa aaactcagtg
    66301 gccgaatcaa ggaaggcttt gaaatgattg caaaagaaat ggaagatcaa ggtggaggta
    66361 acgcccttgt tgtcagccat ggaatgacta ttggaaccat tgtttatctg attaatggca
    66421 tgcatccgca tggtctggat aatggtagcg tgacaatcct tgaatatgag gacggccagt
    66481 ttagggttga agttgtcggt gaccgtagtt accgagagct aggacgtgag aagatggaag
    66541 aaggctctat ttaatcagtc tagacttgct tgccatgagc tagggatttg ataagaatat
    66601 caagataaga aaaaacagcc gagggcactc ctttcggctg tttttgatgt ggaaaactaa
    66661 agtgtaatgc tattgctttt agagattttc ataaacaaga gcaaggaacc tactgttaga
    66721 acagtcagga tagttgacaa ggttgcggct acaccgtaat ttcctctgag aacctctgta
    66781 taaatagcta cagtcattgt tcttgttttg acattgtaga ggaggataga agtagagagt
    66841 tttgaaatca ttgtgactca agataagatg gctccagaaa tgataccaga tagcatcatt
    66901 ggagttgtaa tcttagcaaa ggtattgaga cgactacttc ctaagctttc agcagcttct
    66961 tcaatacttg gtgctatttg ttgtaagcta gcaacagatg agcgaatagt ataaggtaat
    67021 cttctggcag atagagacat aatcaagatg aaagcagtcc ctgtaatcat aagaaatcca
    67081 cttccaaata gaccagtatt gaaggaagaa atgaaggcaa tccctagaac ggttcctggt
    67141 acaatataag gtaccatact gaggctgtca attaagtttg taaacaaatt ccgttttcta
    67201 acggctaggt aggagataaa tgtcgcaaat agaacaacta gaactaaggc aatcaaaggg
    67261 atacgaatgg tattgaaaat agcagatccc atacgatgga aagctacctt gtaactgttt
    67321 ggagaataac ctttaacaga taccatacct gatgttttta ggaaagaggt ataaattaag
    67381 tagatttgag gtaaaacaga gataaagata attccgtaga ctgttgcata aatggcagcc
    67441 atttttcctt ttgtagtttt tttaggctca attggatgga gcagattcat gctgaaactg
    67501 tagcggtttg caatgtgttt ttggataagg aaaattgcca aggcaatgat aatcgccata
    67561 attgcaaaag cagaatttcc tccaacctcg ctaataaatt gggtataaat caggacaggg
    67621 aaagtccgat acccttcgcc aatcaacata ggcgttccaa agtctgagaa tgctctcata
    67681 aatacaagca aggagctgct agtaaggttg gaactaggag aggtaaaaca accgttacga
    67741 taggtttaaa tccgaaggac cccatgcttt cagctgcttc aagtagagaa ttgtcaatac
    67801 tgttcattgt tccagcaaca tatagaaata ccagtgggaa tagttgcagt gtaaagacaa
    67861 gtacaattcc tttgaatcaa taaatatcga tagctggaag ataaagggca tttgtcaaaa
    67921 atttagtgat gacctcattt cgtcctagca agagaaccca ggagtaggct cctacgaaag
    67981 gagctgacat ggaagcaatg ataatcaata tttgtagaaa tttcttcccc ttgaagtcat
    68041 acatagagaa gagataagct aatagggttc ctacaactaa ggaagtgata gtagcggtaa
    68101 tggaaacctt gaaactgttg actagtgtct cagagtagta ggctttacta aagaaagtga
    68161 caaaattagc tagtgagaat tgtccttcat gtataagtgc ttgcttgagc acggtaacga
    68221 taggataaac gagaaagata ggataggtaa gaaagaggaa gaaagaggaa actgtccaaa
    68281 tatttagttt tttacgttcc atggttgact ccttttatca ggttttggga accatctgca
    68341 gaaaagatgt ttaatttttg cgtattgatt cgtagacgaa tacgattgcc tttttgtaga
    68401 tcttcttcaa aagttgattc ttcactaact tgaatttttg aggcaaaacc tgtctcaatg
    68461 aaataatccg tatttagtcc aagatagacg ctatctctaa tagttccttc aatatctcca
    68521 gattcatctt tgataaactc ttcgggacga atgcttacat gaatagcttg ctcctcaacc
    68581 tgatcaagag ctggcattcg aagggcatag ccatctgaaa agacgatata agcgccgtcg
    68641 ctccgttttt caagattggc agggataata tttgtgcgtc cgataaaggt tgccacaaac
    68701 tcattagctg gtttatgata gagttctttt ggtcggccga tttgttggat caccccatct
    68761 ttcataacag caatttggtc tgaaatagcc atggcttctt cttggtcgtg ggttacataa
    68821 acagttgtaa ttcccacttc gtgttggatt tctcggatgg cttgacgcat atccaagcga
    68881 agtttggcct ccagattact aagtggctcg tccatgagga gaacacttgg attaaccgct
    68941 aaggcgcatg ccaaggtgac acgttgttgt tgtccaccac tgagtttatc gggctttcga
    69001 tccgcatatt gagcaatttg catgagttca agatacttgt tggtctgttg aatcaattct
    69061 tcttttggaa ccttcttttg cataagacca aaagcaacgt tgtctcggac agtcaaatgt
    69121 gggaaaatag cgtagttttg gaaaaccatc ccgatattgc gtttgctggg ttccatatta
    69181 ttgatttttg tatcatcgaa gtaaaattct ccaccttcga tactgttgaa acctgcaatc
    69241 atacgaagaa gggtcgtttt cccacatcct gaagctccaa gaagggtaaa gagacttcct
    69301 tttggaattg taatgttcaa attctcaata acagggacat cgtggtagat ttttttggcg
    69361 ttaataattt tgatctcact catagtgaac ctcttttact gtttagattg gatatctgta
    69421 aagacttcgt tgtatttctt aacgatatct gatttattct tgatgacata atcataatct
    69481 tcagtgagtg ttttgatttt gtcaattggt ttcatgtttt cgcttgtttt agcattttta
    69541 cgaacaggac ggttagtagt ggttgtacca agtgtatctt gtacttcttg agagataata
    69601 aaatcgataa atttcttggc attttccata tttttagatt ttttaacgat agcagcacta
    69661 gcaggtagga agacggttcc ttcttttgga tagactacct taatgttagc tccgtcattt
    69721 aagagtttaa ctgctggatc ttcataagag agaccaacag ccatttctcc atcagcgact
    69781 actttataga cactagatga acttgaaccg attttaccat caataagtgt gaaaagatct
    69841 tttacataag accaagcctt atcatctttg taaccacctt gagcttgtag catatttgtt
    69901 aattgagcaa aggcgctaga agagtttgct gggtcagcag ttgcgatttt tccttttagt
    69961 tcaggtttga aaagatcgtt atatccttcg atgttcatgc ctttagttaa atcagggttg
    70021 acgattaaaa cactaccatc tagtgtataa ggagtagagt agccagttgt gttttgatat
    70081 tctttgataa cattatcatt ttcttttgaa gtatagtttt caaagagttc tccgtgggta
    70141 gtatattgtg tataagaacc accaaagata acatcagcta caggaacttc tttttctgac
    70201 tctagttttt tgaaaagttc tccagtacca gcttgaatca gttctacttt gataccatat
    70261 ttttcttcaa aggcaggaat agttgctcca attaagccct ctgagtttgg tgaataaacg
    70321 actagcgaac cgccgtctcc tttatcagat gaactgtcat cggcagattc attagaagaa
    70381 caagcagcat aatacatcca tttctttttc atgatggata cctccgttgt gttatttaag
    70441 tttattttaa aacaatgtaa gcgtttttaa aacatacaat tctattctat agtgtattga
    70501 atctataaca gtacactttg actgctaaaa tatttctata aattaatttg actttcctga
    70561 tagagatgtt cacatcttat ttcaattcac tatattagag taaaattctc tacaaaaaga
    70621 agaatagcct attttactat tcttctgagt gatttcaatt cctttgggga aatatggaga
    70681 tactttttaa atcctgacaa atggttgttt ctttttctaa atcggtgata ctgtatcgga
    70741 gaatgcgcgt gaggtcacaa aggctgcgat agagcttcta tggagaattt ctttttggag
    70801 agatttttta aaggaatgag acatccgcta cctccttgga aggttttttt gtgataagta
    70861 tagcagttta aaaattctag agcaaggtaa aatagaaaag gtttggctaa aattttttag
    70921 ctaaaccttt tgaaaagtta agtatgtatt atagatgctt gttatctgca aatagctaga
    70981 gcatttcaag gaaataaact agaaataaca attaatatgg tggttcagaa ataccttttg
    71041 ataatcaata agatcttcag gatgaagtgc gttgattcca tccatttcat atttccgatt
    71101 taataaacga tatttgtttt caccaaattg atgaaaaggg agtagttgaa cttggtcgat
    71161 atttaatgag ttaaatagag tagcgaattt ttctgcatcc tctaaactat tgttaaaatt
    71221 aggaataact gggattctta aaacgatagt tttattttgt gaaaaagcat aatgaatgtt
    71281 tttaataatc atttgattaa aaaccccagt cactttttta tgttttatag aattataatg
    71341 ttttaggtct gtgtagataa aatccacata ttgaattaaa tcaataaatt tttcatgatc
    71401 aacaaaggca gtagtttcaa tggcagtgtg tatgtgatgt tctttagctg attttaagat
    71461 ggctttagca aattcaaact gagcaaatat ttcacctcct gataaagtta aacctccacc
    71521 ggattcttcg taaaattctt tgtcttttaa tacctctgta ataatttctt ctacagtctt
    71581 ttcttcaccg actaaggtga atttctctcg ttgagcatct ttcatttttt caggtttcat
    71641 tctttgagat tcaggattag aacaccatgg acagcgcaga ggacatcctt ttaaaaaaac
    71701 agttgtacga atacccggac cgtcatgaat tgaaaagtgt tgaatattaa aaataattcc
    71761 tttagatatt tccataagag ttcctcctct tcataagtct atcctatcac aaaaacgaaa
    71821 gaaaaacaat tacgaacgaa aggttaattt gttgtttttt gctttttatt ttggtagaat
    71881 aaaacggagg tgtaaaatga aaagattgga acaaattatt aaattagtat cagaatatga
    71941 aaagatcgac gttaatacat tatcggaaaa attaaatgta tcgaaagtaa cgattagaaa
    72001 agatttagat aaattagagt caaaaggttt attacacaga gagcatggat atgctgtatt
    72061 aaatagtgga gatgacttaa atgtacgttt gtcaattaat tatgaaacta agagaaaaat
    72121 tgttcaggaa gcagtaaaat tggtgtcaga taatgaaaca ataatgatag aatctggatc
    72181 gacctgtgct ttacttgctg aggaaatttg caagcaaaaa agaaatgtta cgattgtaac
    72241 aaattcgttt tttatagcaa attttgtgag agcttatgat tcatgtcgtg ttattgttct
    72301 tggtggtgag tttcagaaag attcacaggt gactgtagga cctttattaa aagaaatgat
    72361 acagactttt catgtgtgtc aagcttttgt tgggacagat ggttacgata aagagatggg
    72421 ctttaccgga aaagatttaa tgcgcagtga ggtagttcaa tatatttcag cagtgtcgga
    72481 taaagtcatt gtcctaactg actcaagtaa atttgataaa agaggtacag taagaagatt
    72541 tgctttaagt caagtctatg aagtaataac agacgaaaaa ctttctaaac aaaatatagc
    72601 tacattagaa aatgctggga taatggttaa ggtagtttcg taagaggtta agtgtatgaa
    72661 tcaagatagg aataaactgc tttctaaaat tgcttatctg tattatattg aaaacttaaa
    72721 tcagtcacaa atagcagcaa aattaggaat ttatagaacc tctattagta gaatgttaac
    72781 agaagcaagg aatgtaggaa ttgttaaaat tgaaatagag aattttgata ccaatatgtt
    72841 taagttggaa aattatgtaa aagaaaaata cagtttggaa agtttagaaa ttattccaaa
    72901 tgaatttgat gatactccaa caattttatc tgaaagaatt tctcaagttg cagcaggcgt
    72961 ccttaggaat ctaattgatg ataatatgaa aattggcttt tcttggggga aaagtttaag
    73021 taatttagta gatttaattc acagtaaaag tgtccgaaat gttcacttct atcctctagc
    73081 aggtggtcct agtcacatac acgctaaata ccatgtgaat acactgattt atgaaatgtc
    73141 tagaaaattt catggagagt gtacatttat gaatgcaacg attgtgcaag aaaataaatt
    73201 gttagcagat ggtattttgc aatcaagata ttttgaaaat ttgaaaaata gttggaaaga
    73261 tttagatata gctgtagtcg gaattggtga ttttagcaat aaagggaaac atcaatggtt
    73321 agacatgctt acagaggatg actttaaaga attgaccaaa gttaaaactg taggagaaat
    73381 ttgttgtcga ttttttgatt caaaaggtaa agaagtctat gaaaacttac aggaaagaac
    73441 gatagcaatc tctttggaag atttaaaaaa tattcctcaa agtttagctg ttgcttacgg
    73501 tgatacgaaa gtatcttcga ttctttctgt cttgcgtgct aatttagtaa atcatttgat
    73561 tacagacaaa aatacaattt taaaagtttt ggaagaagat ggggatttga cttttagaga
    73621 gattctaggt gagtgaaaat gatagactga ttcagtttat cgtttttctt tttagttgat
    73681 tgcacatttg tgcttatata aacaaaaata gtttatctgt tgtttttgga ttgacaactt
    73741 tattatgtag ttgtattcta tagttacaaa agaaaatttt aaaatttcaa atgaaaaaag
    73801 ctttttacat agtgaaatga ggaggaattt atggaaatga ttgttccaga tcaaattatc
    73861 atgggtttaa ttttatatgc tggtgatgcg aaacaacata tttataaagc gttagattac
    73921 ataaaaaatg gtacatgtga acggtgtgaa gaagaaatac agttagctga tgcagcctta
    73981 ttagaagctc ataatctaca aacaaaattt ttggcacagg aagcgtctgg tacaaagaca
    74041 gaaattacag ctctctttgt tcattcacaa gatcatctca tgaccagtat gacggagatt
    74101 aatttaatca aagaaattat tagtttgaga aaagaacttc ataaaaaata atactagagt
    74161 attatcattg ttattaacat agaggaggaa aacataatgg tgaagattgg tttgttttgt
    74221 gcagcaggtt tttctactgg tatgcttgta aataatatga aaattgcagc gcaatctagt
    74281 ggagttgagg cagaaataga ggcgttttct cagtctaaat tagcggatta tgcgccaaat
    74341 atagatgttg cactattggg tccacaagtt gcttatacat tagataaatc aaaagaaatt
    74401 tgtgataagt gtgatgttcc gatagctgtt attccgatga tggactatgg tatgttagat
    74461 gggaaaaaag tattagattt ggccctatct ttgattagtg ggtaagaaaa ggagatttat
    74521 tatgtcaaag atggatgttc agaaaatcat tgcaccgatg atgaagtttg tgaatatgcg
    74581 tggcattata gctctaaaag atgggatgtt agcaattttg ccattgacag tagttggtag
    74641 tttgttcttg attatgggac aattgccgtt cgaaggatta aataagagca ttgctagtgt
    74701 ttttggagct aattggacag agccgtttat gcaagtatat tcaggaactt ttgctattat
    74761 gggtctaatt tcttgttttt caattgccta ttcttatgct aagaatagcg gagtagaggc
    74821 tttaccagct ggagttctat ctgtatctgc attctttatt ttgctaagat catcttatat
    74881 ccctaaacaa ggtgaggcga ttggggacgc tattagtaaa gtttggtttg gaggccaagg
    74941 aattatcggt gctatcatta taggtttggt agtaggaagt atttatacct tctttataaa
    75001 gagaaaaatt gttattaaga tgccagaaca agttccacaa gctattgcca aacagtttga
    75061 agcaatgatt ccagcatttg taattttctt atcttctatg attgtatata ttttagcgaa
    75121 gtcattgact aatggcggaa cattcataga aatgatttat tctgctattc aagttccgtt
    75181 gcaaggttta actggatctt tgtatggtgc tattggaatt gcattcttta tatcattttt
    75241 gtggtggttt ggtgttcatg ggcaatcggt agtaaatgga gtagtgacag ctctgctttt
    75301 atctaatctt gatgctaata aagctatgtt agcctctgct aatctatcat tagaaaatgg
    75361 tgcacatatt gttactcaac aatttttaga ttcattttta attctatcag gttcagggat
    75421 tacgtttggt cttgtagttg ccatgctttt tgcagcaaaa tcaaaacaat accaagcctt
    75481 aggaaaagtt gcagcttttc cagcaatatt taacgtaaat gagccagttg tatttggatt
    75541 tccgattgtc atgaatccag ttatgtttgt acctttcatt cttgttcctg tacttgcagc
    75601 tgtgatagta tatggagcta ttgcaacagg tttcatgcag ccattctcag gggtaacatt
    75661 gccttggagt acaccagcta ttttatcagg atttttggtg ggtggatggc aaggagttat
    75721 tactcagctg gtgatattag cgatgtctac attggtttat tttccattct ttaaagtaca
    75781 ggatcgttta gcttaccaaa atgaaatcaa acaatcttag aggtatttgt gtgttactgt
    75841 taaactcaca catttgtgct aaaaattaga gagttaaaat ttttctagtt aaaagcttga
    75901 aaatttctat aaaaatcggt attatatttt cgaaagaaat aaaaatattt tcgaaagaaa
    75961 ggtgcttacg atggtaaata cagaagtagc aagaacaaca atcaagacag aatattttgg
    76021 cagccttact gaaaggatga acaaatatcg agaagatgtt ttaaataaaa aaccttatat
    76081 tgatgctgag agagcagttc tagcaacacg cgcctatgaa cgatacaagg aacaacctaa
    76141 tgtcctaaaa cgtgcatata tgctgaaaga aattttggaa aatatgacta tctatattga
    76201 agaagaatct atgattgcgg gaaatcaagc ttcttccaat aaagatgctc ctatttttcc
    76261 ggaatatacg ctagaatttg ttctcaatga gttggatctt tttgaaaagc gtgatggaga
    76321 tgttttctat attacagaag aaacaaaaga acaacttaga agtattgctc cgttttggga
    76381 aaataataat ttacgtgcta gagctggtgc cttattacct gaagaagtgt ctgtttatat
    76441 ggaaacagga ttcttcggta tggaaggtaa gatgaattct ggagatgctc acttagcagt
    76501 taactatcag aaacttttgc aatttggttt aagaggtttt gaagagcggg ctcgtaaagc
    76561 aaaagtagct ctagatttaa cagatccagc aagtattgat aaatatcatt tttacgactc
    76621 tatatttatc gtaatcgatg ctattaaagt atatgcaaag cgctttgttg ctcttgctaa
    76681 aagtttagcc gaaaatgcaa atcctaaacg taagaaagaa ttacttgaga ttgcagatat
    76741 ttgctctaga gtcccatatg aaccggcaac tacttttgca gaagctattc aatcagtttg
    76801 gtttattcaa tgtattttac aaattgaatc taatggccac tctctttcat atggccgttt
    76861 tgatcaatat atgtatccat atatgaaggc tgatttagaa agtggtaaag aaacagaaga
    76921 tagcattgtt gaacgtctga caaatctttg gattaagaca attacaatta ataaggttcg
    76981 cagtcaatca catacatttt cttcagcagg aagtccttta tatcaaaatg ttacaattgg
    77041 tggacagact cgagataaga aggatgctgt taacccatta tcttatttgg tattaaaatc
    77101 agttgcacaa acccatctac cgcaacctaa tctaactgta cgttaccatg caggtttaga
    77161 tgctcgtttc atgaatgagt gtattgaagt gatgaaactt ggttttggta tgcctgcatt
    77221 taataatgat gagattatta ttccttcttt tattgcaaaa ggagtattgg aagatgatgc
    77281 ttatgattac agtgccattg gatgtgttga aacggcagtt ccagggaaat ggggctatcg
    77341 ttgcacaggt atgagttata tgaacttccc taaggttcta cttatcacga tgaatgatgg
    77401 aattgatccg gcttcgggta aacggtttgc accaagcttt ggtcgtttta aggatatgaa
    77461 gaacttttct gaattagaaa atgcttggga taaaacacta agatatttga cacgaatgag
    77521 tgttattgtt gaaaattcta ttgatttatc attggaacga gaagttcctg atattctatg
    77581 ttcagcattg actgatgatt gtattggtcg tggaaaacac cttaaagaag gtggagcagt
    77641 atatgattat atatcaggat tgcaagttgg aattgcaaat ttgtcggatt cattagctgc
    77701 aattaaaaaa ttggtgtttg aggaagaacg tataagccca agtcagcttt ggcatgcact
    77761 ggaaacagat tatgccggag aagaaggtaa ggtcattcaa gaaatgttga ttcatgatgc
    77821 acctaagtat ggtaatgatg atgattatgc tgacaaattg gttactgctg cttatgacat
    77881 ttatgttgat gaaattgcta aatatcctaa tacacgttat ggaagagggc ctattggagg
    77941 aattcgttat tcaggaacat cttctatctc agccaacgta gggcagggac gtggaacatt
    78001 agcaactcca gatggacgca acgcgggtac accgttagca gagggttgtt caccatcaca
    78061 taatatggat caacacggcc ctacatctgt tttaaaatct gtttcaaaat taccaacaga
    78121 tgaaatcgta ggtggggttc tcttaaatca gaaagtaaat cctcaaacgt tagccaaaga
    78181 agaagataaa ttaaaactaa ttgctttgtt acgaacattc tttaatcgtt tacatgggta
    78241 ccatattcaa tacaatgttg tttccagaga gacgctgatt gacgctcaga aacatcctga
    78301 aaaacacaga gacttaattg ttcgtgttgc aggatactct gcattcttca atgttctttc
    78361 taaggcaacc caagatgaca ttataggacg tactgagcat actttgtaaa ataaagaggt
    78421 tctttttatg gaatttatgc ttgacacatt aaatttagat gagattaaaa agtggtctga
    78481 aattttgccg ctagctgggg taacttcaaa tcccactatt gcaaaaagag agggttctat
    78541 taattttttt gaacgaatca aagatgtaag agaattgatt ggctctacac cctctattca
    78601 tgttcaggtg atttctcaag attttgaagg catcttaaag gatgctcata aaattcgaag
    78661 acaagcagga gatgatatat ttatcaaagt acctgttact ccagctggat tacgtgcaat
    78721 aaaggcgcta aaaaaagagg gctaccatat cactgcaaca gctatttata cagttattca
    78781 gggattatta gctatcgaag caggagcgga ttacctagct ccatattata atagaatgga
    78841 aaatctgaac attgattcaa attctgtcat tcgtcaatta gctcttgcta ttgatagaca
    78901 gaactctcct agtaagattt tagctgcatc ctttaaaaat gtagcacaag taaataatgc
    78961 tttagctgca ggtgcgcatg ctgttacagc aggagcggat gtttttgaat cagctttcgc
    79021 catgccatct atccaaaagg cggttgatga tttttctgac gattggtttg ttattcaaaa
    79081 tagtcgttcc atttagatag agaggaaata catatgagaa tttttgctag tccttctaga
    79141 tatattcagg gggaaaatgc cttgtttgaa aatgccaaat caattttgga tttgggaaat
    79201 tgccctattc tattatgcga tcagttggtt tatgatattg ttggaaaacg atttgaagat
    79261 tacctacata ggtatggttt ccatattgtt ctggcgctat ttaatggtga agcttctgac
    79321 aatgaaatca atcgagttgt tgccttggct gagaaagaaa attgtgatag tattatcggt
    79381 cttggtgggg gaaagacgat tgatagcgca aaagctattg cagatttgat tgaaaagcct
    79441 gttattattg ctccaacaat tgcatcgacc gacgcacctg tatctgcttt atctgttatt
    79501 tatacagatg aaggtgcatt tgatcattat ctattttatt ctaaaaatcc agatttagtt
    79561 ttggttgata caaaagttat ttcacaagcc cctaagcgtt tattagcgtc tggtattgca
    79621 gatggtttag caacttgggt tgaggcgcgt gcggttatgc aggcaaatgg aaaaactatg
    79681 ttgggacaac agcaaacatt ggctggagtt gcaattgcga agaaatgtga agaaacgctg
    79741 tttgcagatg gtttacaggc tatggcagct tgtgaagcta aagtggtgac accagcatta
    79801 gaaaatattg ttgaagctaa tactttattg agtggtctag gttttgaaag tggaggatta
    79861 gctgcggcgc atgcaattca taatggtttt actgcattga caggtgacat tcatcattta
    79921 acacatggtg aaaaagtagc ttatggaact ttagtacaac tattattgga aaatagacct
    79981 aaagaagaac ttgataagta tattgagttt tacaaaaaaa ttggtatgcc aacaactcta
    80041 aaagaaatgc atttggatca agttggatat gatgatttaa taaaagttgg taaacaagca
    80101 actatggagg gtgagacaat tcatcagatg ccgtttaaga tttcgccttc agatgttgct
    80161 caagctatta tcgctgtaga tgcctatgta aattcaaaat aaacaataag gactactgtt
    80221 ttccaaatgg tagtctttta ttgatccctg tattgaattc tatagaagat tgaaatagga
    80281 tgagaacaaa tcgattggga aagtaaaatt aatttctata aatgttttag caattgtttc
    80341 gtactatttc agattcagtc tactatatgt tcttcataaa tcaaaaagcg acataggttg
    80401 tcggctattt attgtgaata cattaattag cattccagtt ttatcttcgg tctaaaataa
    80461 gtattttgtg ctatacgaga taagcttctt gacttactcc ttgatttact gcataacaat
    80521 gggataaaaa gtgggagata gagcaattca tagtcatcaa aattaatgag atacagtata
    80581 cagtttttcc tttaaacaca tttcaaattc cctcaaaaat ggtataatag taacatcaca
    80641 aaattggaga gagaccatga gtttttacaa tcataaagaa attgagccta agtggcaggg
    80701 ctactgggca gaacatcata catttaagac aggaacagat acatcaaaac ctaagtttta
    80761 tgcgcttgat atgttccctt atccgtctgg agctggtctg cacgtaggac acccagaagg
    80821 ttatactgca accgatatcc tcagtcgtta caaacgtgcg caaggctaca atgtccttca
    80881 cccaatgggt tgggatgctt ttggtttgcc tgcagagcaa tacgctatgg atactggtaa
    80941 tgacccagca gaatttacag cggaaaacat tgccaacttc aaacgtcaaa ttaatgcgct
    81001 tggattttct tatgactggg atcgtgaagt caacacaaca gatccaaact actacaagtg
    81061 gactcaatgg attttcacca agctttacga aaaaggcttg gcctatgaag ctgaagtgcc
    81121 agtaaactgg gttgaggaat tgggaactgc cattgccaat gaagaagtgc ttcctgacgg
    81181 aacttctgag cgtggaggct atccagttgt ccgcaaacca atgcgccaat ggatgctcaa
    81241 aatcacggct tacgcagagc gcttgctcaa tgacttagat gaactagatt ggtcagagtc
    81301 tatcaaggat atgcaacgca actggattgg taaatcaact ggtgccaatg taactttcaa
    81361 agtaaaagga acagacaagg aatttacagt ctttactact cgtccggaca cacttttcgg
    81421 tgcgactttc actgtcttgg ctcctgaaca tgaattagta gacgctatca caagttcaga
    81481 gcaagcagaa gctgtagcag actataaaca ccaagccagc cttaagtctg acttggctcg
    81541 tacagacctt gctaaagaaa aaacaggggt ttggactggt gcttatgcca tcaaccctgt
    81601 caatggtaag gaaatgccaa tctggattgc agactatgtc cttgctagtt atggaacagg
    81661 tgcggttatg gctgtgcctg cccacgacca acgtgactgg gaatttgcca aacaatttga
    81721 ccttccaatc gtcgaagtac ttgaaggtgg aaatgtcgaa gaagctgcct acacagagga
    81781 tggcctgcat gtcaattcag acttcctaga tggattgaac aaagaagacg ctattgccaa
    81841 gattgtggct tggttggaag aaaaaggctg tggtcaggag aaggttacct accgtctccg
    81901 cgactggctc tttagccgtc aacgttactg gggtgagcca attccaatca ttcattggga
    81961 agatggaact tcaacagctg ttcctgaaac tgaattgccg cttgtcttgc ctgtaaccaa
    82021 ggatatccgt ccttcaggta ctggtgaaag tccactagct aacttgacag attggcttga
    82081 agtgactcgt gaagatggtg tcaaaggtcg tcgtgaaacc aacactatgc cacaatgggc
    82141 tggttcaagc tggtactacc tccgctatat tgacccgcac aatactgaga aattggctga
    82201 tgaggacctc ctcaaacaat ggttgccagt agatatctac gtgggtggtg cggaacatgc
    82261 tgtacttcac ttgctttatg ctcgtttctg gcataaattc ctctatgacc tcggtgttgt
    82321 tccgactaag gaaccattcc aaaaactctt taaccaaggg atgattttgg gaacaagcta
    82381 ccgtgaccac cgtggtgctc ttgtggcaac cgacaaggtt gaaaaacgtg atggttcctt
    82441 cttccatgta gaaacagggg aagagttgga gcaagcgcca gccaagatgt ctaaatcgct
    82501 caagaacgtt gttaacccag acgatgtggt ggaacaatac ggtgccgata cccttcgtgt
    82561 ttatgaaatg tttatgggac cactcgatgc ttcgattgct tggtcagaag aaggtttgga
    82621 aggaagccgt aagttccttg accgagttta ccgtttgatt acaagtaaag aaatccttgc
    82681 ggaaaacaat ggtgctcttg acaaggttta caacgaaaca gtcaaagctg ttactgagca
    82741 aattgagtct ctcaaattca acacagctat tgcccaactt atggtctttg tcaatgctgc
    82801 taacaaggaa gataagcttt atgttgacta tgccaaaggc tttattcaat tgattgcacc
    82861 atttgcacct cacttggcag aagaactctg gcaaacagtc gcagaaacag gtgagtcaat
    82921 ctcttatgta gcttggccaa cttgggacga aagcaaattg gttgaagatg aaattgaaat
    82981 tgtcgtccaa atcaaaggaa aagttcgtgc caaactcatg gttgctaaag atctatcacg
    83041 tgaagaatta caagaaatcg ctttagctga tgaaaaagtc aaagcagaaa ttgacggtaa
    83101 ggaaatcgtg aaagtaattg cggtaccgaa taaactcgtt aatatcgtcg ttaaataacg
    83161 agtttattag ctctatctgc caccttcaat agtccactgg actattgaag ccaactaaat
    83221 tagttaacat tgttgtgaaa taagatagga gtccttcaga gtagaatctg gaggattttt
    83281 tgaatcttct tatgaaagta tgatatacta tgggcaacta taaagtttga aaagtgaaat
    83341 aaggagaata agatgccagt aaatgaatat ggtcaaatga ttggggagtc aatggaagct
    83401 tatactccag gtgaattgcc ttcttttgat ttcttagaag ggcgttatgc taggatagag
    83461 gctctttcag tggaaaagca tgcggaggat ttattagctg tttatggccc tgatacgcct
    83521 cgggagatgt ggacctacct ctttcaggag tcagtagcag acatggagga actggtcagc
    83581 cttttaaatc agatgttggc tcgtaaggac cgtttttatt atgcaatcat agacaaggca
    83641 actggtaagg ctttgggaac tttttccctc atgcgaattg atcagaataa ccgagtaata
    83701 gaagtgggag ctgtcacttt ttctccagag ctcaggggga cacggatagg aacagaagcc
    83761 cagtatctct tggcttgcta tgtctttgag gagcttaact atcgtcgcta tgagtggaaa
    83821 tgcgatgctc ttaacctgcc atccagacga gcagcggaac gtttgggatt tatttatgaa
    83881 ggaaccttcc gtcaggcagt ggtttataag gggcgtacaa gagatacgga ttggttgtct
    83941 atgattgata aggactggcc tcaagtcaaa gctcgattgg aaatatggtt gcgtcctgaa
    84001 aactttgata aaaatggacg acagcacaag agcttgagag aactttaaga ggtgttgaga
    84061 tgattactat taaaaagcaa gaaattgtca agctagagga tgttttgcat ctctatcagg
    84121 ctgtcggttg gacaaactat acccatcaaa cagagatgct ggagcaggcc ttatctcatt
    84181 cattagtaat ttatctggca cttgatggtg atgctgtggt gggcttgatt cgtttggttg
    84241 gagatggttt ttcatcagtt tttgtacagg atttgattgt tttgcctagc tatcagcgtc
    84301 aagggattgg tagctccttg atgaaagagg ctttaggaaa ttttaaagag gcctatcaag
    84361 tccagctggc gacagaagag acagaaaaaa acgtgggatt ttatcgttct atgggctttg
    84421 aaatcttatc cacctatgac tgtacaggaa tgatttggat aaacagagaa aaataaaaaa
    84481 acttgtttgt tcttaagcaa agtttaagga tggtctagta tcatatagtc attaaataaa
    84541 gacctcctaa ctttatttaa taaaatccta aacttttttc atcacaatct cctaatgaag
    84601 ccacccaatc aggtggcttt tttgc
//
LOCUS       DAVFER010000003        74340 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1105170250
            SAMEA2167659-rid19724873.denovo.003, whole genome shotgun sequence.
ACCESSION   DAVFER010000003 DAVFER010000000
VERSION     DAVFER010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2167659
            Sequence Read Archive: ERR388902
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 74340)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 74340)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928716.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928716.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 04:07:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,118
            CDSs (total)                      :: 2,073
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 120
            CDSs (without protein)            :: 120
            Pseudo Genes (ambiguous residues) :: 0 of 120
            Pseudo Genes (frameshifted)       :: 67 of 120
            Pseudo Genes (incomplete)         :: 47 of 120
            Pseudo Genes (internal stop)      :: 34 of 120
            Pseudo Genes (multiple problems)  :: 23 of 120
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..74340
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2167659-rid19724873.denovo.003"
                     /strain="1105170250"
                     /db_xref="taxon:1313"
     gene            complement(5..1234)
                     /locus_tag="VU534_000182"
     CDS             complement(5..1234)
                     /locus_tag="VU534_000182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HEU1512840.1"
                     /translation="MNNSQQMLQALEEQDLTKAEHYFAKALENDSSDLLYELATYLEG
                     IGFYPQAKEIYLKIVEDFPEVHLNLAAIASEDGQIEEAFTYLEEIQADSDWYVSSLAL
                     KADLYQLEGLTDVAREKLLEALTYSEDSLLILGLAELDSELENYQAAIQAYAQLDNRS
                     IYEQTGISTYQRIGFAYAQLGKFETATEFLEKALELEYDDLTAFELASLYFDQEEYQK
                     ATLYFKQLDTISPDFEGYEYGYSQALHKEHQVQEALRIAKQGLEKNPFETRLLLAASQ
                     FSYELHDASGAENYLLTAKEDAEDTEEILLRLATIYLEQERYEDILELQSEEPENLLT
                     KWMIARSYQEMDDLDTAYEYYQELTGDLKDNPEFLEHYIYLLRELGHFEEAKVHAHTY
                     LKLVPDDVQMQELFERL"
     gene            complement(1224..2390)
                     /locus_tag="VU534_000183"
     CDS             complement(1224..2390)
                     /locus_tag="VU534_000183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HEU1512841.1"
                     /translation="MEQKEKHFSLSWFFKWFLDNKAITVFLVTLLLGLNLFILSKISF
                     LFSPVLDFLAVVMLPVILSGLLYYLLNPIVDWMEKHKVNRVIAITIVFVIIALFIIWG
                     LAVAIPNLQRQVLTFARNVPVYLEDIDRIVNGLVAQHLPDDFRPQLEQVLTNFSSQAT
                     VLASKVSSQAVNWVSAFISGASQVIVALIIVPFMLFYLLRDGKGLRNYLTQFIPRKLK
                     EPVGQVLSDVNQQLSNYVRGQVTVAIIVAVMFIIFFKIIGLRYAVTLGVTAGILNLVP
                     YLGSFLAMLPALVLGLIAGPVMLLKVVIVFIVEQTIEGRFVSPLILGSQLNIHPINVL
                     FVLLTSGSMFGIWGVLLGIPVYASAKVVISAIFEWYKVVSGLYELEGEEVKSEQ"
     gene            2534..3547
                     /locus_tag="VU534_000184"
     CDS             2534..3547
                     /locus_tag="VU534_000184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000665618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactonase family protein"
                     /protein_id="HEU1512842.1"
                     /translation="MKETVYFGTYTRRTSQGIYKADFDTETGQLSNLELFAAEPSPTY
                     LAFDQHQHLYTVGSQDDKGGIAAYQTDGTVLNHVVEEGAPHCYVAVDEKRDLVYAANY
                     HKGQVLVYKRQEDGSLLLSDMDQHSGQGPHENQASPHVHYTDLTPDHYLVTCDLGTDQ
                     VITYDLDQEGKLSKLYTYHSKPGAGSRHIIFHNHYKIAYLICELNSTIEVLIYDGVGE
                     FERMQVISTLPEAYEGFNGTAAIHLSKDGKYLYASNRGHDSIAVYTILADGSLELLEI
                     VPTHGQTPRDFDLTPDQKFLIVVHQDSDNATVFKRNCDNGRLAELSNDFHVPEAVCIR
                     FAP"
     gene            complement(3592..4011)
                     /locus_tag="VU534_000185"
     CDS             complement(3592..4011)
                     /locus_tag="VU534_000185"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HEU1512843.1"
                     /translation="MAQLTVQIVTPDGLVYDHHASYVSVRTLDGEMGILPRHENMIAV
                     LAVDEVKVKRIDDKDHVNWIAVNGGVIEIANDMITIVADSAERARDIDISRAERAKLR
                     AERAIEEAQDKHLIDQERRAKIALQRAINRINVGNRL"
     gene            complement(4022..5428)
                     /gene="atpD"
                     /locus_tag="VU534_000186"
     CDS             complement(4022..5428)
                     /gene="atpD"
                     /locus_tag="VU534_000186"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HEU1512844.1"
                     /translation="MSSGKIAQVIGPVVDVLFAAGEKLPEINNALVVYKNDERKTKIV
                     LEVALELGDGMVRTIAMESTDGLTRGMEVLDTGRPISVPVGKETLGRVFNVLGDTIDL
                     EAPFTEDAERQPIHKKAPTFDELSTSSEILETGIKVIDLLAPYLKGGKVGLFGGAGVG
                     KTVLIQELIHNIAQEHGGISVFAGVGERTREGNDLYWEMKESGVIEKTAMVFGQMNEP
                     PGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQP
                     TLATEMGQLQERITSTKKGSVTSIQAIYVPADDYTDPAPATAFAHLDSTTNLERKLVQ
                     LGIYPAVDPLASSSRALAPEIVGEEHYAVAAEVKRVLQRYHELQDIIAILGMDELSDE
                     EKTLVARARRIQFFLSQNFNVAEQFTGQPGSYVPVAETVRGFKEILDGKYDHLPEDAF
                     RGVGSIEDVIAKAEKMGF"
     gene            complement(5514..6392)
                     /locus_tag="VU534_000187"
     CDS             complement(5514..6392)
                     /locus_tag="VU534_000187"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002895995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HEU1512845.1"
                     /translation="MAVSLNDIKTKIASTKNTSQITNAMQMVSAAKLGRSEEAARNFQ
                     VYAQKVRKLLTDILHGNGAGASTNPMLISRSVKKTGYIVITSDRGLVGGYNSSILKAV
                     MELKEEYHPDGKGFEMICIGGMGADFFKARGIQPLYELRGLSDQPSFDQVRKIISKTV
                     EMYQNELFDELYVCYNHHVNTLTSQMRVEQMLPIVDLDPNEADEEYSLTFELETSREE
                     ILEQLLPQFAESMIYGAIIDAKTAENAAGMTAMQTATDNAKKVINDLTIQYNRARQAA
                     ITQEITEIVAGASALE"
     gene            complement(6408..7913)
                     /locus_tag="VU534_000188"
     CDS             complement(6408..7913)
                     /locus_tag="VU534_000188"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HEU1512846.1"
                     /translation="MAINAQEISALIKQQIENFKPNFDVTETGVVTYIGDGIARAHGL
                     ENVMSGELLNFENGSYGMAQNLESTDVGIIILGDFTDIREGDTIRRTGKIMEVPVGES
                     LIGRVVDPLGRPVDGLGEIHTDKTRPVEAPAPGVMQRKSVSEPLQTGLKAIDALVPIG
                     RGQRELIIGDRQTGKTTIAIDTILNQKDQDMICIYVAIGQKESTVRTQVETLRQYGAL
                     DYTIVVTASASQPSPLLFLAPYAGVAMAEEFMYQGKHVLIVYDDLSKQAVAYRELSLL
                     LRRPPGREAFPGDVFYLHSRLLERSAKVSDELGGGSITALPFIETQAGDISAYIATNV
                     ISITDGQIFLGDGLFNAGIRPAIDAGSSVSRVGGSAQIKAMKKVAGTLRIDLASYREL
                     EAFTKFGSDLDAATQAKLNRGRRTVEVLKQPVHKPLPVEKQVTILYALTHGFLDTVPV
                     DDIVRFEEEFHAFFDAQHPEILETIRDTKDLPEEAVLDAAITEFLNQSSFQ"
     gene            complement(7928..8464)
                     /locus_tag="VU534_000189"
     CDS             complement(7928..8464)
                     /locus_tag="VU534_000189"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HEU1512847.1"
                     /translation="MDKKTVKVIEKYSMPFVQLVLEKGEEDRIFSDLTQIKQVVEKTG
                     LPSFLKQVAVDESDKEKTIAFFQDSVSPLLQNFIQVLAYNHRANLFYDVLVDCLNRLE
                     KETNRFEVTITSAHPLTDEQKTRLLPLIEKKMSLKVRSVKEQIDESLIGGFVIFANHK
                     TIDVSIKQQLKVVKENLK"
     gene            complement(8464..8958)
                     /gene="atpF"
                     /locus_tag="VU534_000190"
     CDS             complement(8464..8958)
                     /gene="atpF"
                     /locus_tag="VU534_000190"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HEU1512848.1"
                     /translation="MHVTVGELIGNFILITGSFILLLVLIKKFAWSNITGIFEERAEK
                     IASDIDRAEEARQKAEVLAQKREDELAGSRKEAKTIIENAKETAEQSKANILADAKLE
                     AGHLKEKANQEIAQNKVEALQSVKGEVADLTISLAGKIISQNLDSHAHKALIDQYIDQ
                     LGEA"
     gene            complement(8972..9688)
                     /gene="atpB"
                     /locus_tag="VU534_000191"
     CDS             complement(8972..9688)
                     /gene="atpB"
                     /locus_tag="VU534_000191"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HEU1512849.1"
                     /translation="MEESINPIISIGPVIFNLTMLAMTLLIVGVIFVFIYWASRNMTL
                     KPKGKQNVLEYVYDFVIGFTEPNIGSRYMKDYSLFFLCLFLFMVIANNLGLMTKLQTI
                     DGTNWWSSPTANLQYDLTLSFLVILLTHIESVRRRGFKKSIKSFMSPVFVIPMNILEE
                     FTNFLSLALRIFGNIFAGEVMTSLLLLLSHQAIYWYPVAFGANLAWTAFSVFISCIQA
                     YVFTLLTSVYLGNKINIEEE"
     gene            complement(9723..9923)
                     /locus_tag="VU534_000192"
     CDS             complement(9723..9923)
                     /locus_tag="VU534_000192"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015545704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit C"
                     /protein_id="HEU1512850.1"
                     /translation="MNLTFLGLCIACMGVSVGEGLLMNGLFKSVARQPDMLSEFRSLM
                     FLGVAFIEGTFFVTLVFSFIIK"
     gene            complement(9998..11004)
                     /locus_tag="VU534_000193"
                     /pseudo
     CDS             complement(9998..11004)
                     /locus_tag="VU534_000193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153868.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            complement(11449..11847)
                     /locus_tag="VU534_000194"
     CDS             complement(11449..11847)
                     /locus_tag="VU534_000194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000428147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU1512851.1"
                     /translation="MENKESHKSQEIGNLIRVYNRSKREEAESEPLNLYVEDEKGNLL
                     AGLIAETFGNWLEIEYLFVKEELRGQGIGSKLLQQAESEAKNRNCCFAFVNTYQFQAP
                     DFYQKHGYKEVFSLQDCLYIRQRYYYQKNL"
     gene            complement(12355..12837)
                     /gene="greA"
                     /locus_tag="VU534_000195"
     CDS             complement(12355..12837)
                     /gene="greA"
                     /locus_tag="VU534_000195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018370745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HEU1512852.1"
                     /translation="MAEKTYPMTLEEKEKLEKELEELKLVRRPEVVERIKIARSYGDL
                     SENSEYEAAKDEQAFVEGQISSLETKIRYAEIVNSDAVAQDEVAIGKTVTIQEIGEDE
                     EEVYIIVGSAGADAFVGKVSNESPIGQALIGKKTGDTATIETPVGSYDVKILKVEKTA
                     "
     gene            complement(12908..14563)
                     /gene="mltG"
                     /locus_tag="VU534_000196"
     CDS             complement(12908..14563)
                     /gene="mltG"
                     /locus_tag="VU534_000196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HEU1512853.1"
                     /translation="MSEKSREEEKLSFKEQILRDLEKVKGYDEVLKEDEAVVRTPANE
                     PSTEELMADSLSTVEEIMRKAPTVPTHPSQGVPASPADEIQRETPGVPSHPSQDVPSS
                     PAEESGSRPGPGPVRPKKLEREYNETPTRVAVSYTTAEKKAEQAGPETPTPATETVDI
                     IRDTSRRSRREGAKPVKPKKEKKSHVKAFVISFLVFLALLSAGGYFGYQYVLDSLLPI
                     DANSKKYVTVGIPEGSNVQEIGTTLEKAGLVKHGLIFSFYAKYKNYTDLKAGYYNLQK
                     SMSTEDLLKELQKGGTDEPQEPVLATLTIPEGYTLDQIAQAVGQLQGDFKESLTAEAF
                     LAKVQDETFISQAVAKYPTLLESLPVKDSGARYRLEGYLFPATYSIKESTTIESLIDE
                     MLAAMDKNLSPYYSTIKSKNLTVNELLTIASLVEKEGAKTEDRKLIAGVFYNRLNRDM
                     PLQSNIAILYAQGKLGQNISLAEDVAIDTNIDSPYNVYKNVGLMPGPVDSPSLDAIES
                     SINQTKSDNLYFVADVTEGKVYYANNQEDHDRNVAEHVNSKLN"
     gene            complement(14644..15138)
                     /locus_tag="VU534_000197"
     CDS             complement(14644..15138)
                     /locus_tag="VU534_000197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000702438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU1512854.1"
                     /translation="MKIRQARLEDLDRIVELEFENFSVEEAIPPSVFEAHLREIQTSF
                     LVAEKEGRIMGYIEGPVGLHRHLQDQSFTEEIKDYSHEPGGYISVTCLSIAKEAQGLG
                     LGQKLLTALKEVALEDERDGINLTCHDYLIAYYEKHGFVNEGQSQSTFAGETWYDMVW
                     EMKK"
     gene            complement(15135..15599)
                     /locus_tag="VU534_000198"
     CDS             complement(15135..15599)
                     /locus_tag="VU534_000198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU1512855.1"
                     /translation="MEIPIKIIQASKSDLPEIGALQTSSFPAEKQQLSHILEESIRKC
                     ADTFLLARDENQLLGYILSSPQSDNPQCLKVHSLVIEFDHQRQGLGTLLLAALKEVAV
                     ELDYKGIRLESPDELLSYFEMNGFVDEEATLLYATSQGYSMIWFNPFYLEEQ"
     gene            complement(15609..16943)
                     /locus_tag="VU534_000199"
     CDS             complement(15609..16943)
                     /locus_tag="VU534_000199"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HEU1512856.1"
                     /translation="MSKTYHFIGIKGSGMSALALMLHQMGHKVQGSDVEKYYFTQRGL
                     EQAGITILPFDEKNLDGDMEIIAGNAFRPDNNVEIAYADQNGISYKRYHEFLGSFMRD
                     FVSMGVAGAHGKTSTTGMLSHVLSHITDTSFLIGDGTGRGSANAKYFVFESDEYERHF
                     MPYHPEYSIITNIDFDHPDYFTSLEDVFNAFNDYAKQITKGLFVYGEDAELRKITSDA
                     PIYYYGFEAEGNDFVASDLLRSITGSTFTVHFRGQNLGQFHIPTFGRHNIMNATAVIG
                     LLYTAGFDLNLVREHLKTFAGVKRRFTEKIVNDTVIIDDFAHHPTEIIATLDAARQKY
                     PSKEIVAVFQPHTFTRTIALLDDFAHALNQADAVYLAQIYGSAREVDHGDVKVEDLAN
                     KINKKHQVITVENVSPLLDHDNAVYVFMGAGDIQTYEYSFERLLSNLTSNVQ"
     gene            complement(16954..17571)
                     /locus_tag="VU534_000200"
     CDS             complement(16954..17571)
                     /locus_tag="VU534_000200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HEU1512857.1"
                     /translation="MKQERFPLVSDDEVMLTEMPVMNLYDESDLISNIKGEYRDKNYL
                     EWAPIAEEKPVKPIEKQVEKPKKAPLGVKKEGKSYAEVAREEARADLKKKRSANYLTQ
                     DFSLARRHSQPSLVRQGNQPTAPFQKENPGEFVKYSQKLTQSHYILAEEVHSIPTKNE
                     EVSAPAPKKNNYDFLKKSQIYNKKSKQTEQERRVAQELNLTRMTE"
     gene            complement(17619..20717)
                     /locus_tag="VU534_000201"
     CDS             complement(17619..20717)
                     /locus_tag="VU534_000201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEU1512858.1"
                     /translation="MAKLIPGKIRIEGVALYETGKVDIIKEKNNRLYARVAEEELRYS
                     LEDDLVFCACDFFQKRGYCVHLAALEHFLKNDERGQEILWSLEEGHEEKEAVETKVTL
                     GGKFLDRILSPKSECAYELSAVGQVEAGTNHILWTLRIGQINSQKYYVIRDIPLFLRI
                     VEQRKSYMIGKIYEESLSWEAFDDASQELLTFLHGLTEEGLVPDLFFQNQGRHLFFPL
                     TFFEQGVNLLMALPHFQFDHQVDSYQTLLFQDMHADANLFAFTVTEYSDYFEMEISES
                     PRVNVFYQGAVLFHKGQVYFLTDQQMRLLKEIKALPVGQQGKKYLQFDSSDRDKLASC
                     LTLFIQMGTVSAPERLQIKTFAPSFYFDREEDNRIRLEIQFDYGNRQVSSRQELEELP
                     FSSDADLEERIFQVCLAAGFEADFQSWRQALKAESVYHFFHDIIPVFEKLGHVDLSDK
                     LEELYSLASPQVQIASKGGLLEIQFDFQNIVQEEIDQAMQALVANQDFYIDSSNQVYF
                     FDEETKKIRQNLQELGQFELKDGTLQARKSLAYSLAHLFEGRDRVSFSQEFQNLAQDL
                     THPEDFPLQATQVKADLRDYQEKGIGWLQMLHHYGFGGILADDMGLGKTLQTIAFLTS
                     QVTKESRVLILAPSGLIYNWADEFQKFAPQLDVTVVHGLKASREEILAESHQIYVTSY
                     ATFRQDSEFYQGMAFDFLFLDEAQVMKNAQTKIAQTLRQFVVPSVFALSGTPIENHLG
                     ELWSIFQIVMPGLLPSKKEFMKLPAERVAQFIKPFVMRRKKEEVLTELPDLIEVVYKN
                     ELEDQQKAIYLAQLQQMRDHLAQVSEQEFQRSRVEILSGLMRLRQICDTPALFMEDYQ
                     GASGKLDSLRDLLVQVADGGHRVLIFSQFKGMLEKIEQELPDLGLTSFKITGSTPAKE
                     RQDMTKAFNQGERDAFLISLKAGGVGLNLTGADTVILVDLWWNPAVEAQAIGRAHRMG
                     QEETVEVYRLVTKGTIEEKIQELQEQKKHLVSQVLDGTESRGSLTLAEIREILGISEA
                     ST"
     gene            complement(20810..21976)
                     /locus_tag="VU534_000202"
     CDS             complement(20810..21976)
                     /locus_tag="VU534_000202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEU1512859.1"
                     /translation="MGKYDFTSLPNRLGHHTYKWKETETDSEVLPAWIADMDFVVLPE
                     IRQAVQTYADQLVYGYTYASEDLIKEVQKWEATQYGYNFDKEALVFIEGVVPAISTAI
                     QTFTKEGEAVLINTPVYPPFARSVKLNNRRLITNSLVEKDSLFEIDFDQLEKDLVEEE
                     VKLYVLCNPHNPGGRVWEKEVLEKIGQLCQKHGVLLVSDEIHQDLTLFGHKHQSFNTI
                     NPAFKNFAIVLSSATKTFNIAGTKNSYAVIENPKLRLAFQKRLLANNQHEISGLGYLA
                     TEAAYRYGKDWLEELKQVFEDHINYVMDLFGKETKIKVMKPQGTYLIWLDFSAYDLTD
                     ETLQELLRNEAKVILNRGLDFGEEGSLHARINIAMPKSLLQEVCQRIVATFAKR"
     gene            complement(21984..23078)
                     /locus_tag="VU534_000203"
     CDS             complement(21984..23078)
                     /locus_tag="VU534_000203"
                     /EC_number="2.5.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HEU1512860.1"
                     /translation="MSKELHINTILAQAGIKSDEATGALVTPLHFSTTYQHPEFGRST
                     GFDYTRTKNPTRSKAEEVLAAIESADYALATSSGMSAIVLAFSVFPVGSKVLAVRDLY
                     GGSFRWFNQVEQEGHFHFTYANTEEELIAELEKDVDVLYIETPTNPLMLEFDIEKLAK
                     LAHAKGAKVVVDNTFYSPIYQRPIEDGADIVLHSATKYLAGHNDVLAGVVVTNSLELY
                     EKLFYNLNTTGAVLSPFDSYQLLRGLKTLSLRMERSTANAQEVVAFLKDSPAVKEVLY
                     TGRGGMISFKVADETRIPHILNSLKVFSFAESLGGVESLITYPTTQTHADIPAEVRHS
                     YGLTDDLLRLSIGIEDARDLIADLRQAIEG"
     gene            complement(23236..24357)
                     /locus_tag="VU534_000204"
     CDS             complement(23236..24357)
                     /locus_tag="VU534_000204"
                     /inference="COORDINATES: protein motif:HMM:NF012869.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU1512861.1"
                     /translation="MTEKIQEHELIKTNQAEKSVQDVLDNCIERVQNNSLKSDRVTSF
                     ETPFALLFIFATIAVMLTYGGYRVSAGYISVGTLVSFLIYLFQLLNPISNIANFVTVY
                     SRSKGSSVALENLLAVPKEKFEGGKSVSGRGLNFNHVYFGYDENRPVLKDITCSIFKG
                     QKIAFVGPSGSGKSTIVRLLERFYKPLSGDILMEQSSIYDFNLKEWRSKIAWVSQNNA
                     VLSGSIRDNLCLGLNRLVTDDELMKVLDLVSLGDEIRSMKEGLDTEVGERGRLLSGGR
                     SQRLQIARAYLKDAEILIFDEATANLDADSEYAIISSLYSVLKEKTVVIIAHRLSTVK
                     DVDCIFFLEEGKITGSGTHKELLENHERYARFVQEQMIE"
     gene            complement(24366..24911)
                     /locus_tag="VU534_000205"
     CDS             complement(24366..24911)
                     /locus_tag="VU534_000205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU1512862.1"
                     /translation="MKLKLLRVDTKVIMGSFLLVLSSLLALLLPLILKDLIDGSSIEN
                     IGSKVFQSFLIFIGQALFSSIGYYLFSQSGEKKIAKIRKKVIEGLIYVEKSFFDKSQS
                     GELTSAIVNDTSVIREFLITTFPNIILSLVMVLGSIVVLFSLDWNLSLLLFITLPCMM
                     FIILPLSNISEKYSRRLQEEI"
     gene            complement(25083..27041)
                     /locus_tag="VU534_000206"
     CDS             complement(25083..27041)
                     /locus_tag="VU534_000206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000748873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEU1512863.1"
                     /translation="MKKSKSKYLTLAGLVLGTGVLLSACGNSSTASKTYNYVYSSDPS
                     SLNYLAENRAATSDIVANLVDGLLENDQYGNIIPSLAEDWTVSQDGLTYTYKLRKDAK
                     WFTSEGEEYAPVTAQDFVTGLQYAADKKSEALYLVQDSVAGLDDYITGKTSDFSTVGV
                     KALDDQTVQYTLVKPELYWNSKTLATILFPVNADFLKSKGDDFGKADPSSILYNGPFL
                     MKALVSKSAIEYKKNPNYWDAKNVFVDDVKLTYYDGSDQESLERNFTAGAYTTARLFP
                     NSSSYEGIKEKYKNNIIYSMQNSTSYFFNFNLDRKSYNYTSKTSDIEKKSTQEAVLNK
                     NFRQAINFAFDRTSYGAQSEGKEGATKILRNLVVPPNFVSIKGKDFGEVVASKMVNYG
                     KEWQGINFADGQDPYYNPEKAKAKFAEAKKELEAKGVQFPIHLDKTVEVTDKVGIQGV
                     SSIKQSIESVLGSDNVVIDIQQLTSDEFDSSGYFAQTAAQKDYDLYHGGWGPDYQDPS
                     TYLDIFNTNSGGFLQNLGLEPGEANDKAKAVGLDVYTQMLEEANKEQDPAKRYEKYAD
                     IQAWLIDSSLVLPSVSRGGTPSLRRTVPFAAAYGLTGTKGVESYKYLKVQDKIVTTDE
                     YAKAREKWLKEKEESNKKAQEELAKHVK"
     gene            complement(27244..28866)
                     /locus_tag="VU534_000207"
     CDS             complement(27244..28866)
                     /locus_tag="VU534_000207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HEU1512864.1"
                     /translation="MSHENNHQQAQMLRGTAWLTASNFISRLLGAVYIIPWYIWMGAY
                     AAKANGLFTMGYNIYAWFLLVSTAGIPVAVAKQVAKYNTMREEEHSFALIRSFLGFMT
                     GLGLVFALVLYVFAPWLADLSGVGKDLIPIMQSLAWGVLIFPSMSVIRGFFQGMNNLK
                     PYAMSQIAEQVIRVIWMLLATFIIMKLGSGDYLAAVTQSTFAAFVGMVASFAVLIYFL
                     AQEGSLKRIFETGDKINSKRLLVDTIKEAIPFILTGSAIQLFQILDQLTFINSMSWFT
                     NYSNEDLVVMFSYFSANPNKITMILISVGVSIGSVGLPLLTENYVKGDLKAASRLVQD
                     SLTLLFMFLLPATVGVVMVGEPLYTVFYGKPDSLALGLFVFAVLQSIILGLYMVLSPM
                     LQAMFRNRKAVLYFIYGSIAKLVLQLPTIALFHSYGPLISTTIALIIPNVLMYRDICK
                     VTGVKRKVILKRTILISLLTLVMFLLIGTIQWLLGFFFQPSGRLWSFFYVALVGAMGG
                     GLYMVMSLRTYLLDKVIGKAQADRLRAKFKLS"
     gene            28972..30417
                     /locus_tag="VU534_000208"
     CDS             28972..30417
                     /locus_tag="VU534_000208"
                     /EC_number="6.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-
                     lysine ligase"
                     /protein_id="HEU1512865.1"
                     /translation="MIKIETVLDILKKDGLFREIIDQGHYHYNYSKVIFDSISYDSRK
                     VTEDTLFFAKGAAFKKEYLLSAITQGLAWYVAEKDYEVGIPVIIVNDIKKAMSLIAME
                     FYGNPQEKLKLLAFTGTKGKTTAAYFAYNILSQGHRPAMLSTMNTTLDGETFFKSALT
                     TPESIDLFDMMNQAVQNDRTHLIMEVSSQAYLVKRVYGLTFDVGVFLNISPDHIGPIE
                     HPSFEDYFYHKRLLMEKSRAVIINSDMDHFSVLKEQVEDQDHDFYGSQFDNQIENSKA
                     FSFSATGKLAGDYDIQLIGNFNQENAVAAGLACLRLGASLEDIKKGIAATRVPGRMEV
                     LTQKNGAKVFIDYAHNGDSLKKLINVVETHQTGKIALVLGSTGNKGESRRKDFGLLLN
                     QHPEIQVFLTADDPNYEDPMAIADEISSYINHPVEKIADRQEAIKAAMAITNHELDAV
                     IIAGKGADCYQIIQGKKESYPGDTAVAENYL"
     gene            complement(30460..30657)
                     /locus_tag="VU534_000209"
     CDS             complement(30460..30657)
                     /locus_tag="VU534_000209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HEU1512866.1"
                     /translation="MSLENKLEQATGAVKEGFGKVTGDSKTELEGAVEKTVAKAKDVV
                     EDAKGAVEGAVEGLKNVFTKE"
     gene            complement(30758..31366)
                     /locus_tag="VU534_000210"
                     /pseudo
     CDS             complement(30758..31366)
                     /locus_tag="VU534_000210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809149.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1803 domain-containing protein"
     gene            complement(31391..31903)
                     /locus_tag="VU534_000211"
     CDS             complement(31391..31903)
                     /locus_tag="VU534_000211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000892254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoylalanyl-D-glutamate--2,
                     6-diaminopimelate ligase"
                     /protein_id="HEU1512867.1"
                     /translation="MLENGDLIFVRDGSDMGQAIQTSTGNYSHVAIYLDGMIYHASGQ
                     AGVVCQEPADFFESNHLYDLYVYPEMDIQSVKERACKHLGAPYNASFYPDAAGFYCSQ
                     YIAEILPIFETIPMKFGDGEQEISDFWREYYIELGLPVPLNQAGTNPSQLAASPLLQC
                     KERNLHDSDF"
     gene            complement(31989..32924)
                     /locus_tag="VU534_000212"
     CDS             complement(31989..32924)
                     /locus_tag="VU534_000212"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HEU1512868.1"
                     /translation="MSKILVFGHQNPDSDAIGSSVAFAYLAKEAYGLDTEAVALGTPN
                     EETAFVLNYFGVEAPRVITSAKAEGAEQVILTDHNEFQQSVSDIAEVEVYGVVDHHRV
                     ANFETASPLYMRLEPVGSASSIVYRMFKEHGVAVPKEIAGLMLSGLISDTLLLKSPTT
                     HPTDKIIAPELAELAGVNLEEYGLAMLKAGTNLASKSAEELIDIDAKTFELNGNNVRV
                     AQVNTVDIAEVLERQAEIEAAMQAANESNGYSDFVLMITDIVNSNSEILALGANMDKV
                     EAAFNFKLENNHAFLAGAVSRKKQVVPQLTESFNA"
     gene            complement(32995..33294)
                     /locus_tag="VU534_000213"
     CDS             complement(32995..33294)
                     /locus_tag="VU534_000213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HEU1512869.1"
                     /translation="MDHKAYMYVLECRDGSYYIGYTTDMRRRLAIHNSGKGAKYTRAR
                     LPVKLIYAQGFASKEEAMSAEALLKRKKRPQKEEFLSENQDRNLLSYFEESWGVL"
     gene            complement(33284..34033)
                     /locus_tag="VU534_000214"
     CDS             complement(33284..34033)
                     /locus_tag="VU534_000214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HEU1512870.1"
                     /translation="MEEEQLLKSGERINQLFSTDIKIIQNREVFSYSVDSVLLSRFPR
                     FPKKGLIVDFCAGNGAVGLFASTRTQAQILSVEIQERLADMAERSVRLNGLEEQMQVI
                     CDDLKNMPAHIQGSKVDMILCNPPYFKVNPYSNLNESEHYLLARHEITTNLEEICRSA
                     QSILKSNGRLAMVHRPDRLLDILDTLKRHNLAPKRLQFVYPKREKEANMLLIEAIKDG
                     STSGFKVLPPLIVHNDDGSYTPEIEEIYYGS"
     gene            complement(34087..34446)
                     /locus_tag="VU534_000215"
     CDS             complement(34087..34446)
                     /locus_tag="VU534_000215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000689596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HEU1512871.1"
                     /translation="MKIGDKLKGRITGIQPYGAFVELETGDTGLIHISEIRTGFIENI
                     HETLKVDEEVQVQVVDLDEFTGKASLSIRTLEEEKYQFPRRRRFSSDRFNYGFAPFRR
                     MLPIWTGEALHHLKKKK"
     gene            complement(34448..35848)
                     /locus_tag="VU534_000216"
     CDS             complement(34448..35848)
                     /locus_tag="VU534_000216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional Cof-type HAD-IIB family
                     hydrolase/peptidylprolyl isomerase"
                     /protein_id="HEU1512872.1"
                     /translation="MDAKLRYKAKKIKIVFFDIDDTLRNSKTGFIPTTIPTVFKQLRE
                     KGILTGIASGRGIFGVVPEIRDLKPDFFVTLNGAYIEDKKGQVIYQHQIEKSDVEEYI
                     SWAKQEGIEYGLVGSHDAKLSTRTDMMSEAINPIYPDLDVDPDFHEKEDIYQMWTFED
                     KGDDLHLPDSLSDKLRMVRWHQHSSDIVPISGSKATGVEKVVEHLGLKPEKVMVFGDG
                     LNDLELFDYAGISVAMGISHDKIKEKADYITKTLEEDGIFAALEVFGMVEKELHFPQV
                     DIETVEGPLATIKTNHGDLRIKLFPEHAPKTVANFVSLSKDGYYDGVIFHRIIKDFMI
                     QGGDPTGTGMGGESIYGESFEDEFSEELYNIRGALSMANAGPNTNGSQFFIVQNQHLP
                     YSKKEITRGGWPEPIAEIYANQGGTPHLDRRHTVFGQLADEASYAVLDAIAAVETGAM
                     DKPVEDVVIETIEIED"
     gene            complement(36143..36382)
                     /locus_tag="VU534_000217"
     CDS             complement(36143..36382)
                     /locus_tag="VU534_000217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HEU1512873.1"
                     /translation="MAQQRRGGFKRRKKVDYIAANKIEYVDYKDTELLSRFVSERGKI
                     LPRRVTGTSAKNQRKVTTAIKRARVMALMPFVNED"
     gene            complement(36414..36884)
                     /gene="ssbA"
                     /locus_tag="VU534_000218"
     CDS             complement(36414..36884)
                     /gene="ssbA"
                     /locus_tag="VU534_000218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein SsbA"
                     /protein_id="HEU1512874.1"
                     /translation="MINNVVLVGRMTRDAELRYTPSNVAVATFTLAVNRTFKSQNGER
                     EADFINVVMWRQQAENLANWAKKGSLIGVTGRIQTRSYDNQQGQRVYVTEVVAENFQM
                     LESRSVREGHTGGAYSAPTANYSAPTNSVPDFSRNENPFGATNPLDISDDDLPF"
     gene            complement(36896..37186)
                     /locus_tag="VU534_000219"
     CDS             complement(36896..37186)
                     /locus_tag="VU534_000219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018030687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HEU1512875.1"
                     /translation="MAKYEILYIIRPNIEEEAKNALVARFDSILTDNGATVVESKTWE
                     KRRLAYEIQDFREGLYHIVNVEANDDAALKEFDRLSKINADILRHMIVKIDA"
     gene            complement(37339..38685)
                     /gene="asnS"
                     /locus_tag="VU534_000220"
     CDS             complement(37339..38685)
                     /gene="asnS"
                     /locus_tag="VU534_000220"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HEU1512876.1"
                     /translation="MMTKRVTIIDVKDYVGQEVTIGAWVANKSGKGKIAFLQLRDGTA
                     FFQGVAFKPNFVEKFGEEVGLEKFDVIKRLSQETSVYVTGIVKEDERSKFGYELDITD
                     IEVIGESQDYPITPKEHGTDFLMDNRHLWLRSRKQVAVLQIRNAIIYATYEFFDKNGF
                     MKFDSPILSGNAAEDSTELFETDYFGTPAYLSQSGQLYLEAGAMALGRVFDFGPVFRA
                     EKSKTRRHLTEFWMMDAEYSYLTHDESLDLQEAYVKALLQGVLDRAPQALETLERDTE
                     LLKRYIAEPFKRITYDQAIDLLQEHENDEDADYEHLEHGDDFGSPHETWISNHFGVPT
                     FVMNYPAAIKAFYMKPVPGNPERVLCADLLAPEGYGEIIGGSMREEDYDALVAKMDEL
                     GMDRTEYEFYLDLRKYGTVPHGGFGIGIERMVTFAAGTKHIREAIPFPRMLHRIKP"
     gene            complement(38701..38991)
                     /locus_tag="VU534_000221"
     CDS             complement(38701..38991)
                     /locus_tag="VU534_000221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000384866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEU1512877.1"
                     /translation="MDYKLAFKTSSLISFLSPNSPHPGGDFWLTQGTQDPVHFAFLAE
                     NKEEVQACYEAGLEAGGRDNGAPGYRSEHPIYYAAFMIDLDGNNIEVVCHKE"
     gene            complement(39059..40246)
                     /locus_tag="VU534_000222"
     CDS             complement(39059..40246)
                     /locus_tag="VU534_000222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEU1512878.1"
                     /translation="MKLSNRVLEMEESVTLAAGARAKALKAEGRDILSLTLGEPDFTT
                     PKNIQDAAIASIRDGRASFYTVTSGLPELKAAVNSYFERFYGYSVASNQVTVAAGAKY
                     SLYTFFMAVVNPGDEVIIPTPYWVSYGDQVKMAEGVPVFVSAKEDNHFKVTVEQLEAA
                     RTDKTKVLVLNSPSNPTGMIYTREELLAIGNWAVENDILILADDIYGRLVYNGHEFTP
                     ISSLSEAIRKQTVVINGVSKTYAMTGWRIGYAVGEADIIAAMSKIAGQTTSNPSAVAQ
                     YAAVEALSGEQDTVESMRQAFEERLNTIYPLLAEVPGFEVVKPQGAFYLFPNVKKAME
                     MKGYTDVTDFTTVILEEAEVALVTGAGFGAPENVRLSYATDLDTLKEAVERLKAFMGS
                     END"
     gene            complement(40243..40731)
                     /locus_tag="VU534_000223"
     CDS             complement(40243..40731)
                     /locus_tag="VU534_000223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5590 domain-containing protein"
                     /protein_id="HEU1512879.1"
                     /translation="MKKRQNKAKNNLLWQYGLGMTILFVVISGSFLYMVSLSMKPYQT
                     AKSEGEKLAQQYAGLEQADQVDLYNGLESYYSVLGRNKQQEALAVLIGKDDHKIYVYQ
                     LNQGVSQEKAETVSKEKGAGEIDKITFGRYQDKPIWEVKSGSDFYLVDFETGALVNKE
                     GL"
     gene            41052..41600
                     /locus_tag="VU534_000224"
     CDS             41052..41600
                     /locus_tag="VU534_000224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000039625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEU1512880.1"
                     /translation="MSKKVLFIVGSLRQGSFNHQMALEAEKALAGKAEVSYLDYSALP
                     LFSQDLEVPTHPAVAAAREAVLVADAIWIFSPVYNFSIPGTVKNLLDWLSRALDLSDT
                     RGVSALQDKFVTVSSVANAGHDQLFAIYKDLLPFIRTQGVGDFTAARVNDSAWADGKL
                     VLEETVLNSLEKQAQDLVEAIK"
     gene            complement(41877..42605)
                     /gene="yaaA"
                     /locus_tag="VU534_000225"
     CDS             complement(41877..42605)
                     /gene="yaaA"
                     /locus_tag="VU534_000225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide stress protein YaaA"
                     /protein_id="HEU1512881.1"
                     /translation="MKILIPTAKEMNTDFPSIEAIPLKPESQAVLDALALYSASQLES
                     FYKVSAEKAAEEFQNIQALKRQTAQHYPALKLFDGLMYRNIKRDKLTEAEQDYLENHV
                     FITSALYGVVPVLSPMAPHRLDFLMKLKVAGKTLKSHWKAAYDETLKKEEVIFSLLSS
                     EFETVFSKEIRAKMVTFKFMEDRGGQLKIHSTISKKARGAFLTALIENQVQTVGEARR
                     LNFAGFVYREDLSQPQGLVFVKEV"
     gene            complement(42684..42848)
                     /locus_tag="VU534_000226"
     CDS             complement(42684..42848)
                     /locus_tag="VU534_000226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000508323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YczI family protein"
                     /protein_id="HEU1512882.1"
                     /translation="MGFYLMVASMLLGLLALKIGFSQFKEKKDKFLSILTSLAGTALV
                     LVAVWLGWPK"
     gene            complement(42915..44510)
                     /locus_tag="VU534_000227"
     CDS             complement(42915..44510)
                     /locus_tag="VU534_000227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000822862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1512883.1"
                     /translation="MKRIVFELIFIATTWYIFLPPLNLTSWEFLFFLCGHLLVVAILF
                     GFGKGINLVKTVHVRHGKAEAALNLEGFKINRLGKILLASIGGILLLAALVSLVTSSM
                     FQAKNYANVVTVTEKDFTEFPKSDTSKVPILDRSTAEKIGDRYLGSLTDKVSQYVAAD
                     TYTQLTIDGKPYRVTPLEYADPIKWFNNQAKGIGEYIKVDMVTGNADLVDLKTPIKYS
                     DSEYFNRDVKRHLRLKYPTKIFKTPSFEVDDEGNPFYVATVYQKQFGLAVPRPASVII
                     LDATNGETKEYSLSDVPEWVDRIYPAEETIEQINYNGKYKDGFLNAMISKKNVTQTTN
                     GYNYLSIGNDIYLYTGVTSANADESNLGFILENMRTGEITKYSLASATEESARESAEG
                     AVQEKSYKATFPILINLNDKPLYIMGLKDNAGLVKEYALVDAVEYQNVIVATTVEEML
                     SKYANKNDLEIDNATTESINGVVADLKSAVIKGDTVYFFKVDGKIYKVKASVSDDLPY
                     LENGKTFEGQVGKDNYLKTFKLR"
     gene            complement(44522..44932)
                     /locus_tag="VU534_000228"
     CDS             complement(44522..44932)
                     /locus_tag="VU534_000228"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000412213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HEU1512884.1"
                     /translation="MEKKIVKDILFLSQVSQPASQEDLYLARDLQDTLLANRDTCVGL
                     AANMIGVQKRVIIFNLGLVPVVMFNPVLLSFEGSYEAEEGCLSLVGVRSTKRYETIRL
                     AYRDSKWQEQTITLTGFPAQICQHELDHLEGRII"
     gene            complement(45048..45839)
                     /gene="yghU"
                     /locus_tag="VU534_000229"
     CDS             complement(45048..45839)
                     /gene="yghU"
                     /locus_tag="VU534_000229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001277405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-dependent disulfide-bond
                     oxidoreductase"
                     /protein_id="HEU1512885.1"
                     /translation="MSAYQLPTVWQDEASNQGAFTGLNRPTAGARFEQNLPKGEQAFQ
                     LYSLGTPNGVKVTILLEELLEAGFKEAAYDLYKIAIMDGDQFGSDFVKLNPNSKIPAL
                     LDQSGTENVRVFESAHILLYLAEKFGAFLPSNPVEKVEVLNWLFWQAGAAPFLGGGFG
                     HFFNYAPEKLEYPINRFTMEVKRQLDLLDKELAQKPYIAGNDYTIADIAIWSWYGQLV
                     QGNLYQGSAKFLDASSYQNLVKWAEKIANRPAVKRGLEVTYTEIK"
     gene            complement(45852..48548)
                     /locus_tag="VU534_000230"
     CDS             complement(45852..48548)
                     /locus_tag="VU534_000230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HEU1512886.1"
                     /translation="MSKEQKRQAFYTQSPEEVLQAVDATEQGLSSSEAEKRLAEFGHN
                     ELEEGEKRSILVKFIEQFKDLMIIILVAAAILSVVTSGGEDIADAIIILAVVIINAAF
                     GVYQEGKAEEAIEALKSMSSPVARVLRDGHMAEIDSKELVPGDIVALEAGDVVPADLR
                     LIEANSLKIEEAALTGESVPVEKDLSVELATDAGIGDRVNMAFQNSNVTYGRGMGVVV
                     NTGMYTEVGHIAGMLQDADETDTPLKQNLNNLSKVLTYAILVIALVTFVVGVFIQGKN
                     PLGELLTSVALAVAAIPEGLPAIVTIVLSLGTQVLAKRHSIVRKLPAVETLGSTEIIA
                     SDKTGTLTMNKMTVEKVFYDAVLHDSADDIELGLEMPLLRSVVLANDTKIDVEGNLIG
                     DPTETAFIQYALDKGYDVKGFLEKYPRVAELPFDSDRKLMSTVHPLPDGRFLVAVKGA
                     PDQLLKRCLLRDKAGDIAPIDEKVTNLIRTNNSEMAHQALRVLAGAYKIIDSIPENLT
                     SEELENDLIFTGLIGMIDPERPEAAEAVRVAKEAGIRPIMITGDHQDTAEAIAKRLGI
                     IDANDTEGHVLTGAELNELSDEEFEKVVGQYSVYARVSPEHKVRIVKAWQKQGKVVAM
                     TGDGVNDAPALKTADIGIGMGITGTEVSKGASDMILADDNFATIIVAVEEGRKVFSNI
                     QKTIQYLLSANTAEVLTIFLSTLFGWDVLQPVHLLWINLVTDTFPAIALGVEPAEPGV
                     MNHKPRGRKASFFSGGVLSSIIYQGVLQAALVMSVYGLAIAYPVHVGDNHAIHADALT
                     MAFATLGLIQLFHAYNVKSVYQSILTVGPFKSKTFNWSILVSFILLMATIVVEPLEGI
                     FHVTKLDLSQWGIVMAGSFSMIIIVEIVKFIQRKLGFDKNAI"
     gene            48852..50036
                     /gene="mntE"
                     /locus_tag="VU534_000231"
     CDS             48852..50036
                     /gene="mntE"
                     /locus_tag="VU534_000231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDF family manganese efflux transporter MntE"
                     /protein_id="HEU1512887.1"
                     /translation="MKQSISNLKLAERGAIISISTYLILSAAKLAAGHLLHSSSLVAD
                     GFNNVSDIIGNVALLIGIRMARQPADRDHRFGHWKIEDLASLITSIIMFYVGFDVLRD
                     TIQKILSREETVIDPLGATLGIISAAIMFVVYLYNTRLSKKSNSNALKAAAKDNLSDA
                     VTSLGTAIAILASSFNYPIVDKLVAIIITFFILKTAYDIFIESSFSLSDGFDDRLLED
                     YQKAIMEIPKISKVKSQRGRTYGSNIYLDITLEMNPDLSVFESHEIADQVESMLEERF
                     GVFDTDVHIEPAPIPEDEILDNVYKKLLMREQLIDQGNQLEELLTDDFVYIRQDGEQM
                     DKEAYKTKKELNSAIKDIQITSISQKTKLICYELDGIIHTSIWRRHETWQNIFHQETK
                     KE"
     gene            complement(50179..52050)
                     /locus_tag="VU534_000232"
     CDS             complement(50179..52050)
                     /locus_tag="VU534_000232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001279112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEU1512888.1"
                     /translation="MSDFIVEKLSKSVGDKTVFRDISFIIHDLDRIGLIGVNGTGKTT
                     LLDVLSGVSGFDGDVSPFSAKNDYQIGYLTQDPDFDDRKTVLDTVLSSELKEIQLIRE
                     YELIMLDYSEDKQARLERVMAEMDSLQAWEIESQVKTVLSKLGIQDLSTPVGELSGGL
                     RRRVQLAQVLLGNHDLLLLDEPTNHLDIAIIEWLTLFLKNSKKTVLFITHDRYFLDAL
                     STRIFELDRAGLTEYQGNYQDYVRLKAEQDERDAALLHKKEQLYKQELAWMRRQPQAR
                     ATKQQARINRFHDLKKEVSGSSAETDLTMNFETSRIGKKVIEFQDVSFAYENKPILQN
                     FNLLVQAKDRIGIVGDNGVGKSTLLNLIAGSLEPTAGQVVIGETVRIAYFSQQIEGLD
                     ESKRVINYLQEVAEEVKTSGGSTTSIAELLEQFLFPRSTHGTLIEKLSGGEKKRLYLL
                     KLLLEKPNVLLLDEPTNDLDIATLTVLENFLQGFAGPVLTVSHDRYFLDKVATKILAF
                     EDGKIRPFFGHYTDYLDEKAFETDMANQVQKAEKEKVVKVREDKKRMTYQEKQEWASI
                     EGDIETLEKRIAAIEEEMQANGSDFGKLATLQKELDEKNEALLEKYERYEYLSEFDS"
     gene            complement(52047..53231)
                     /locus_tag="VU534_000233"
     CDS             complement(52047..53231)
                     /locus_tag="VU534_000233"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001138849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HEU1512889.1"
                     /translation="MPSEFQKALPVLEKIKEAGFEAYFVGGSVRDALLHSPIHDVDIA
                     TSSYPEETKQIFPRTADIGIEHGTVLVLDGDEEYEVTTFRTEDVYVDYRRPSAVSFVR
                     SLEEDLKRRDFTVNAFALDETGEIVDLFHGLEDLEKQVLRAVGVASERFNEDALRIMR
                     GFRFQASLGFALEPETFKAMKTLTPLLEKISVERTFVEFDKLLLAPFWRRGLASMIES
                     QAYDYLPDMASSQDKLNRLFDLETDFTFESSEQAWAALLWALEIENAQSFLKSWKTSR
                     QFAKQVQDLLIILALRENGELSKRDCYRFDIDLLLQAENLRQAQGKEVNPQAITEKYQ
                     SLTIHDKKEIQINGGILIKEYGYQPGPDLGEILTEIEFAIVDGELENNREAIHAYLRE
                     KK"
     gene            complement(53243..54010)
                     /locus_tag="VU534_000234"
     CDS             complement(53243..54010)
                     /locus_tag="VU534_000234"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HEU1512890.1"
                     /translation="MSIRVIIAGFKGKMGQAACQMVLTDPDLDLVAVLDPFESESEWQ
                     GIPVFKDKADLAGFEADVWVDFTTPAVAYENTRFALENGFAPVVGTTGFTSEEIAELK
                     EFSRAQDLGGLIAPNFALGAVLLMQFATQAAKYFPNVEIIELHHDKKKDAPSGTAIKT
                     AELMAEVRESIQQGAADEEELIAGARGADFDGMRIHSVRLPGLVAHQEVIFGNQGEGL
                     TLRHDSYDRISFMTGVNLGIKEVVKRHELVYGLEHLL"
     gene            complement(54287..55135)
                     /locus_tag="VU534_000235"
     CDS             complement(54287..55135)
                     /locus_tag="VU534_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEU1512891.1"
                     /translation="MKLAVFTDSSAYLSAEILQREDLFVLDIPVNIDGEEYVEGINLS
                     AEEFYQKMAQASELPKTSQPSIAKLDEILTSLKEQGYTHALGLFLSSGISGFYQNIQY
                     MVDDYEGLTIAFPDTLITSAPLGIMVESVFNWRDQGDDFASIQDKLAIQISRTSAFIM
                     VDDLDHLVKGGRLSNGAAILGNLLSIKPILYFNDQGVIEVYEKVRTEKKATKRLIEII
                     KETTASGQYRVIVIHGNAPEKAEELRQHLLDFGLGSDVSLATFGSVIGTHLGAGSIAL
                     GYILVI"
     gene            complement(55137..55511)
                     /locus_tag="VU534_000236"
     CDS             complement(55137..55511)
                     /locus_tag="VU534_000236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HEU1512892.1"
                     /translation="MNLKREQEFVSQYHFDARNFEWENENGAPETKVDVNFQLLQHDQ
                     ENQVTSLIVILSFMIVFDKFVISGTISQVNHIDGRIVNEPSELNQEEVETLARPCLNM
                     LNRLTYEVTEIALDLPGINLEF"
     gene            complement(55585..56937)
                     /locus_tag="VU534_000237"
     CDS             complement(55585..56937)
                     /locus_tag="VU534_000237"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HEU1512893.1"
                     /translation="MGKYFGTDGVRGEANLELTPELAFKLGRFGGYVLSQHETEAPKV
                     FVGRDTRISGEMLESALVAGLLSVGIHVYKLGVLATPAVAYLVETEGASAGVMISASH
                     NPALDNGIKFFGGDGFKLDDEKEAEIEALLDAEEDTLPRPSAEGLGILVDYPEGLRKY
                     EGYLVSTGTPLDGMKVALDTANGAASTSARQIFADLGAQLTVIGETPDGLNINLNVGS
                     THPEALQEVVKESGSAIGLAFDGDSDRLIAVDENGDIVDGDKIMYIIGKYLSEKGQLA
                     QNTIVTTVMSNLGFHKALNREGINKAVTAVGDRYVVEEMRKSGYNLGGEQSGHVILMD
                     YNTTGDGQLSAVQLTKIMKETGKSLSELAAEVTIYPQKLVNIRVENVMKEKAMEVPAI
                     KAIIEKMEEEMAGNGRILVRPSGTEPLLRVMAEAPTTEEVNYYVDTITDVVRAEIGID
                     "
     gene            complement(56961..57740)
                     /locus_tag="VU534_000238"
     CDS             complement(56961..57740)
                     /locus_tag="VU534_000238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbbR-like domain-containing protein"
                     /protein_id="HEU1512894.1"
                     /translation="MKKNSLYIISSLFFACVLFVYATATNFQNSTSARQVKTETYTNT
                     VTNVPIDIRYNSDKYFISGFASEVSVVLTGANRLSLASEMQESTRKFKVTADLTDAGV
                     GTIEVPLSIEDLPNGLTAVATPQKITVKIGKKAQKDKVKIVPEIDPSQIDSRVQIENV
                     MVSDKEVSITSDQETLDRIDKIIAVLPTSERITGNYSGSVPLQAIDRNGVVLPAVITP
                     FDTIMKVTTKPVAPSSSTSNSSTSSSSETSSSTKATSSKTN"
     gene            complement(57727..58584)
                     /locus_tag="VU534_000239"
     CDS             complement(57727..58584)
                     /locus_tag="VU534_000239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001867651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00159 family protein"
                     /protein_id="HEU1512895.1"
                     /translation="MNFQQLSNLQYWTSLFASPWTIAINLIDILIVAYILYHFTKAIA
                     GTKIMILVRGVLVFILAQILANMIGLTTISWLINQIITYGVIAAVVIFSPEIRTGLER
                     LGRATDFFSNAPISAEEQMIRAFVKSVEYMSPRKIGALVAIQRVRTLQEYISTGIPLD
                     AKISAELLINIFIPNTPLHDGAVIIKEERIAVTSAYLPLTKNTGISKEFGTRHRAAIG
                     LSEVSDALTFVVSEETGGISITYNGRFKHNLTLDEFETELREILLPKEEVGLSFKERL
                     LGGWKHEKK"
     gene            58720..59685
                     /locus_tag="VU534_000240"
     CDS             58720..59685
                     /locus_tag="VU534_000240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000081018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HEU1512896.1"
                     /translation="MSQLYDITIVGGGPVGLFAAFYAHLRQAKVQIIDSLPQLGGQPA
                     ILYPEKEILDVPGFPNLTGEELTNRLIEQLNGFDTPIHLNETVLEIDKQEEFAITTSK
                     GSHLTKTVIIAMGGGAFKPRPLELEGVEGYENIHYHVSNIQQYAGKKVTILGGGDSAV
                     DWALAFEKIAPTTLVHRRDNFRALEHSVQALQESSVTIKTPFAPSQLLGNGKTLDKLE
                     ITKVKSDETETIDLDHLFVNYGFKSSVGNLKNWGLDLNRHKIIVNSKQESSQAGIYAI
                     GDCCYYDGKIDLIATGLGEAPTAVNNAINYIDPEQKVQPKHSTSL"
     gene            complement(59719..60630)
                     /gene="whiA"
                     /locus_tag="VU534_000241"
     CDS             complement(59719..60630)
                     /gene="whiA"
                     /locus_tag="VU534_000241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HEU1512897.1"
                     /translation="MSFTVAVKEEILGQHHLSWHELSAIIKMSGSIGLSTSGLTLSVV
                     TENAKLARHLYESFLHLYEIKSEIRHHQRSNLRKNRVYTVFTDEKVQDLLSDLHLADS
                     FFGLETGIDEAILSDEEAGRAYLCGAFLANGSIRDPESGKYQLEISSVYLDHAQGIAS
                     LLQQFLLDAKVLERKKGAVTYLQRAEDIMDFLIVIGAMQARDDFERVKILRETRNDLN
                     RANNAETANIARTVSASMKTINNISKIKDIMGLENLPVDLQEVAQLRIQHPDYSIQQL
                     ADSLSTPLTKSGVNHRLRKINKIADEL"
     gene            complement(60627..61604)
                     /locus_tag="VU534_000242"
     CDS             complement(60627..61604)
                     /locus_tag="VU534_000242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HEU1512898.1"
                     /translation="MRKPKITVIGGGTGSPVILKSLREKDVEIAAIVTVADDGGSSGE
                     LRKNMQQLTPPGDLRNVLVAMSDMPKFYEKVFQYRFSEDAGAFAGHPLGNLIIAGLSE
                     MQGSTYNAMQLLSKFFHTTGKIYPSSDHPLTLHAVFQDGTEVAGESHIVDHRGIIDNV
                     YVTNALNDDTPLASRRVVQTILESDMIVLGPGSLFTSILPNIVIKEIGRALLETKAEI
                     AYVCNIMTQRGETEHFTDSDHVEVLHRHLGRPFIDTVLVNIEKVPQEYMNSNRFDEYL
                     VQVEHDFVGLCKQVSRVISSNFLRLENGGAFHDGDLIVDELMRIIQVKK"
     gene            complement(61601..62491)
                     /gene="rapZ"
                     /locus_tag="VU534_000243"
     CDS             complement(61601..62491)
                     /gene="rapZ"
                     /locus_tag="VU534_000243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HEU1512899.1"
                     /translation="MTKKQLHLVIVTGMSGAGKTVAIQSFEDLGYFTIDNMPPALLPK
                     FLQLVEIKEDNPKLALVVDMRSRSFFSEIQAVLDELENQDGLDFKILFLDAADKELVA
                     RYKETRRSHPLAADGRILDGIKLERELLAPLKNMSQNVVDTTELTPRELRKTLAEQFS
                     DQEQAQSFRIEVMSFGFKYGIPIDADLVFDVRFLPNPYYLPELRNQTGVDEPVYDYVM
                     NHPESEDFYQHLLALIEPILPSYQKEGKSVLTIAMGCTGGQHRSVAFAKRLAQDLSKN
                     WSVNEGHRDKDRRKETVNRS"
     gene            complement(62543..62923)
                     /locus_tag="VU534_000244"
     CDS             complement(62543..62923)
                     /locus_tag="VU534_000244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HEU1512900.1"
                     /translation="MAKTIHTDKAPKAIGPYVQGKIVGNLLFASGQVPLSPETGEIVG
                     ENIQEQTEQVLKNIGAILAEAGTDFDHVVKTTCFLSDMNDFVPFNEVYQTAFKEEFPA
                     RSAVEVARLPRDVKVEIEVIAEIG"
     gene            complement(62934..63521)
                     /locus_tag="VU534_000245"
     CDS             complement(62934..63521)
                     /locus_tag="VU534_000245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002915299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihA family ribosome biogenesis GTP-binding
                     protein"
                     /protein_id="HEU1512901.1"
                     /translation="MELNTHNAEILLSAANKSHYPQDELPEIALAGRSNVGKSSFINT
                     MLNRKNLARTSGKPGKTQLLNFFNIDDKMRFVDVPGYGYARVSKKEREKWGCMIEEYL
                     TTRENLRAVVSLVDLRHDPSADDVQMYEFLKYYEIPVIIVATKADKIPRGKWNKHESA
                     IKKKLNFDPSDDFILFSSVSKAGMDEAWDAILEKL"
     gene            complement(63530..64762)
                     /gene="clpX"
                     /locus_tag="VU534_000246"
     CDS             complement(63530..64762)
                     /gene="clpX"
                     /locus_tag="VU534_000246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002874765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HEU1512902.1"
                     /translation="MSTNRKNDMMVYCSFCGKNQEEVQKIIAGNNAFICNECVELAQE
                     IIREELVEEVLADLSEVPKPIELLHILNHYVIGQDRAKRALAVAVYNHYKRINFHDTR
                     EESEDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVEN
                     ILLKLLQVADFNIERAERGIIYVDEIDKIAKKSENVSITRDVSGEGVQQALLKIIEGT
                     VASVPPQGGRKHPQQEMIQVDTKNILFIVGGAFDGIEEIVKQRLGEKVIGFGQNNKAI
                     DENSSYMQEIIAEDIQKFGIIPELIGRLPVFAALEQLTVDDLVRILKEPRNALVKQYQ
                     TLLSYDDVELEFDDEALQEIANKAIERKTGARGLRSIIEETMLDVMFEVPSQENVKLV
                     RITKETVDGTDKPILETA"
     gene            complement(64794..64964)
                     /locus_tag="VU534_000247"
     CDS             complement(64794..64964)
                     /locus_tag="VU534_000247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000442275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1512903.1"
                     /translation="MERSLFGLFTAFLCFICFLAGAQAFRKKRYGLSILLWLNAFTNL
                     VNSIHAFYMTLF"
     gene            complement(64964..65470)
                     /locus_tag="VU534_000248"
     CDS             complement(64964..65470)
                     /locus_tag="VU534_000248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000162460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HEU1512904.1"
                     /translation="MTKKIVAIWAQDEEGVIGKENRLPWHLPAELQHFKETTLNHAIL
                     MGRVTFDGMGRRLLPKRETLILTRNPEEKIDGVATFQDVQSVLDWYQAQEKNLYIIGG
                     KQIFQAFEPYLDEVIVTHIHARVEGDTYFPEELDLSLFETVSSKFYAKDEKNPYDFTI
                     QYRKRKEV"
     gene            complement(65600..66118)
                     /locus_tag="VU534_000249"
     CDS             complement(65600..66118)
                     /locus_tag="VU534_000249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HEU1512905.1"
                     /translation="MVELKKEAVKDVTSLTKAAPVALAKTKEVLNQAVADLYVAHVAL
                     HQVHWYMHGRGFLVWHPKMDEYMEALDGQLDEISERLITLGGSPFSTLTEFLQNSEIE
                     EEAGEYRNVEESLERVLVIYRYLSELFQKGLDVTDEEGDDVTNGIFAGAKTETDKTIW
                     MLAAELGQAPGL"
     gene            complement(66614..68118)
                     /gene="lytC"
                     /locus_tag="VU534_000250"
                     /pseudo
     CDS             complement(66614..68118)
                     /gene="lytC"
                     /locus_tag="VU534_000250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_078138769.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="choline binding-anchored murein hydrolase LytC"
     gene            complement(68156..68914)
                     /locus_tag="VU534_000251"
     CDS             complement(68156..68914)
                     /locus_tag="VU534_000251"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000087908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HEU1512906.1"
                     /translation="MSRKPFIAGNWKMNKNPEEAKAFVEAVASKLPSSDLVEAGIAAP
                     ALDLTTVLAVAKGSNLKVAAQNCYFENAGAFTGETSPQVLKEIGTDYVVIGHSERRDY
                     FHETDEDINKKAKAIFANGMLPIICCGESLETYEAGKAAEFVGAQVSAALAGLTAEQV
                     AASVIAYEPIWAIGTGKSASQDDAQKMCKVVRDVVAADFGQEVADKVRVQYGGSVKPE
                     NVASYMACPDVDGALVGGASLEAESFLALLDFVK"
     gene            complement(69012..69689)
                     /locus_tag="VU534_000252"
     CDS             complement(69012..69689)
                     /locus_tag="VU534_000252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain-containing protein"
                     /protein_id="HEU1512907.1"
                     /translation="MTYLDAFKSGTLVLPSALLLHFKELFPSSDDFLVWQFFYLQNTT
                     GLEEMSPSQIAERIGKEISDVNQSISNLTERGLLQYRTIELNGEIELLFDASLALERL
                     DDLFGAVHSSSDQLTPQNQLKDLVETFQQELGRLLTPFEIEDLTKTLKEDGTSADLIK
                     EALREAVLNGKPNWKYIQAILRNWRHEGIKSVAQIEAKRAEREASNPQLTQVSADFIN
                     AMDLWKD"
     gene            complement(69698..70642)
                     /locus_tag="VU534_000253"
     CDS             complement(69698..70642)
                     /locus_tag="VU534_000253"
                     /EC_number="2.3.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001122710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine O-succinyltransferase"
                     /protein_id="HEU1512908.1"
                     /translation="MPIRIDKKLPAVEILRTENIFVMDDQRAAHQDIRPLKILILNLM
                     PQKMVTETQLLRHLANTPLQLDIDFLYMESHRSKTTRSEHMETFYKTFPEVKDEYFDG
                     MIITGAPVEHLPFEEVDYWEEFRQMLEWSKTHVYSTLHICWGAQAGLYLRYGVEKYQM
                     DSKLSGIYPQDTLKEGHLLFRGFDDSYVSPHSRHTEISKEEVLNKTNLEILSEGPQVG
                     VSILASRDLREIYSFGHLEYDRDTLAKEYFRDRDAGFDPHIPENYFKDDDVNQVPCLC
                     WSSSAALFFSNWVNHAVYQETPFDWRKIEDDASAYGYL"
     gene            complement(70824..71336)
                     /locus_tag="VU534_000254"
     CDS             complement(70824..71336)
                     /locus_tag="VU534_000254"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001049318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HEU1512909.1"
                     /translation="MNLKDYIATIENYPKEGITFRDISPLMADGNAYSYAVREIVQYA
                     TDKKVDMIVGPEARGFIVGCPVAFELGIGFAPVRKPGKLPREVISADYEKEYGVDTLT
                     MHADAIKPGQRVLIVDDLLATGGTVKATIEMIEKLGGVMAGCAFLVELDELNGREKIG
                     DYDYKVLMHY"
     gene            complement(71423..72181)
                     /locus_tag="VU534_000255"
     CDS             complement(71423..72181)
                     /locus_tag="VU534_000255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001848902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HEU1512910.1"
                     /translation="MSEAGHKFLAKLGKKRLRPGGKRATDWLIAEGGFSKEKRILEVA
                     CNRGTTAIELAQRFGCKITAVDMDAQALEVAKKSAGTAGVAHLISFERANAMKLPYQD
                     ASFDIVINEAMLTMQADQAKKKCVMEYLRVLKPGGLLLTHDVLLKEAKESIRQELSQA
                     IHVNVGPLTQDGWEQVMIESGYCDVKALTGEMTLMKLSGMIYDEGLLGTLKICVNACK
                     KENRKQFLTMYKMFAKNKQKLGFIAMASYKSSKR"
     gene            complement(72682..73812)
                     /gene="ugpC"
                     /locus_tag="VU534_000256"
     CDS             complement(72682..73812)
                     /gene="ugpC"
                     /locus_tag="VU534_000256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter
                     ATP-binding protein UgpC"
                     /protein_id="HEU1512911.1"
                     /translation="MVELNLKNIYKKYPNSEHYSVEDFNLNIKDKEFIVFVGPSGCGK
                     STTLRMIAGLEDITEGTASIDGVVVNDVAPKDRDIAMVFQNYALYPHMTVYDNMAFGL
                     KLRKYSKEDINKRVQEAAEILGLKEFLERKPADLSGGQRQRVAMGRAIVRDAKVFLMD
                     EPLSNLDAKLRVSMRAEIAKIHRRIGATTIYVTHDQTEAMTLADRIVIMSATKNPAGT
                     GTIGRVEQIGTPQEVYKNPVNKFVAGFIGSPAMNFITVKLVGSEIVSDGFRLKVPEGA
                     LKVLREKGYEGKELIFGIRPEDVNAEPAFLETFPDCVVKATISVSELLGSESHLYCQV
                     GKDEFVAKVDARDYLQTGATVELGFDLNKAHFFDVETEKTIY"
     gene            74140..>74340
                     /locus_tag="VU534_000257"
     CDS             74140..>74340
                     /locus_tag="VU534_000257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU1512912.1"
                     /translation="MEQLHFITKLLDIKDPNIKILDIINMDTHKEIIAKLDYEAPSCP
                     DCGSLMKKYDFQKPSKIPYLETT"
BASE COUNT        21616 a        16810 c        13813 g        22101 t
ORIGIN      
        1 attcttacaa tctctcaaac agttcttgca tttgcacatc atctggaacc agttttaagt
       61 aagtgtgagc atggactttt gcttcttcaa aatgtcccaa ttcacgcaag agatagatat
      121 agtgttccag aaattctgga ttgtccttca aatctcctgt caactcttga taatactcat
      181 aagcagtatc caaatcgtcc atttcttgat aagaacgagc aatcatccac ttggtcaaaa
      241 gattttctgg ctcctcactc tgcaattcta gaatatcctc ataacgctcc tgctccagat
      301 aaatagtggc taaacgaagc aagatttctt ctgtatcctc agcgtcttct tttgcagtaa
      361 ggagataatt ttctgcacca ctagcatcat gcaattcata agaaaattgt gaagcagcta
      421 gcaagaggcg agtttcaaag ggatttttct ctaatccttg cttagcgata cgcagggctt
      481 cttgaacttg atgttcctta tgtaaagcct gactgtaccc atactcatag ccttcaaagt
      541 caggagaaat ggtatcaagc tgcttaaagt agagggtggc tttttgatat tcttcttgat
      601 caaaataaag actggccaac tcaaaagctg ttaagtcatc gtattctaac tccagggctt
      661 tttctaaaaa ctcagtagcc gtttcaaatt tccctaactg agcataggca aagccaattc
      721 gttgataggt ggaaatgccc gtttgctcat aaatcgagcg attatctaac tgggcatagg
      781 cttgaatagc cgcttggtaa ttttccaact cactatccaa ctctgccaaa cccaatatca
      841 agagagaatc ctctgagtag gtcaaggcct ccaataattt ctcacgtgcc acatctgtca
      901 aaccttccag ctggtaaagg tctgccttca gagccaaaga cgagacatac cagtcactgt
      961 cagcttggat ttcctcaaga taggtaaagg cttcttctat ttgaccatcc tcgctagcaa
     1021 ttgcagctag attaagatga acctctggaa aatcctctac aattttcagg taaatttcct
     1081 tggcctgagg atagaaacca atcccttcaa gataagttgc caattcatac agaagatcac
     1141 ttgaatcatt ttctaaagct ttggcgaaat aatgctcagc cttagttaaa tcttgctcct
     1201 ccaaagcctg taacatctgt tgactattgt tcactcttga cttcctcacc ctctaattca
     1261 tatagaccac tgactacctt ataccattcg aaaatggctg aaatgacaac cttagcagag
     1321 gcataaaccg gaataccaag taaaactccc cagataccaa acatagatcc tgaagttaac
     1381 aaaacaaaga gaacattaat agggtggatg tttaattgac ttcccaaaat caatggagag
     1441 acaaaacggc cttcaatagt ttgttctacg ataaagacaa tcactacttt caaaagcatg
     1501 actggaccag caatcaaacc caatactaga gcaggaagca tggctagaaa gctaccaaga
     1561 taagggacca gatttaaaat accagcagta acccccagcg taaccgcata gcgtagacca
     1621 ataatcttga agaagatgat aaacattact gctacaataa tagccactgt cacttgccct
     1681 cgaacatagt tggacaactg ttgattcaca tctgataaaa cttgtccaac aggttccttc
     1741 aattttcttg gaatgaattg ggtcaaatag ttacgcaagc ctttcccatc acgcaagaga
     1801 taaaagagca tgaaaggaac gataatcaag gcaacaatca cttgagaagc cccgctaata
     1861 aaggcactca cccagttgac tgcctgagat gaaaccttac ttgccaaaac tgtagcctgg
     1921 ctagaaaaat tggtcaaaac ttgctctaat tgaggtctga aatcatctgg caggtgctgg
     1981 gctaccaatc cattaacaat cctatctata tcttctaagt aaacaggaac gtttcttgca
     2041 aaggtcaaaa cctgacgttg cagatttgga atggcgactg ccaagcccca aatgataaag
     2101 agagcgatga taacaaagac aatagtgata gctataacac gattaacctt atgcttctcc
     2161 atccaatcaa caataggatt caacaaataa tataacaaac cagacaaaat gactggcaac
     2221 atcacaactg ctaaaaagtc taaaacaggt gaaaatagaa aactaatctt acttaaaata
     2281 aaaagattca gtcccaataa taaggttact aaaaataccg taattgcctt gttatctaaa
     2341 aaccacttga aaaaccaaga taggctaaaa tgtttctctt tttgctccat aaatacttcc
     2401 tttctattgt tctctcatta taccattttt gaaacaaaat aactcttttt taaagtgctt
     2461 acatctaatt ggatatcttt aatttacttg tttttgtgat ataatagtct tatctttaca
     2521 cagaggtata gtaatgaaag aaactgttta ttttggaact tatacacgtc gtacttctca
     2581 agggatttac aaggcagact ttgatacaga aactggtcag ctttcaaatc tagaactttt
     2641 tgcagctgag ccaagtccaa cctaccttgc ctttgaccag caccaacatt tatacactgt
     2701 tggtagccaa gacgataagg ggggaattgc agcctatcaa actgacggga ctgtgttaaa
     2761 tcatgttgtt gaagaaggag ctccccactg ttatgttgct gtcgatgaaa agcgtgattt
     2821 ggtttacgca gctaactatc acaagggaca agtccttgtt tataaacgcc aggaagatgg
     2881 tagtcttcta cttagtgata tggatcaaca cagtggccaa ggtccacatg aaaatcaagc
     2941 ttccccccat gttcactata cagatttaac acctgaccac tatctagtga cctgcgactt
     3001 gggaactgac caagtcatca cctatgacct cgatcaagaa ggaaaattat ctaagctcta
     3061 tacctatcac agcaagccag gagcaggctc acgccatatc attttccata accactataa
     3121 aatcgcttat ctcatttgtg aactcaatag tactatcgaa gttttaatct acgatggcgt
     3181 tggcgaattt gaacgtatgc aggtcatttc aactttaccg gaagcttacg aaggctttaa
     3241 tggaaccgct gctattcatc tctctaaaga cggtaaatac ctctacgctt ctaaccgtgg
     3301 ccatgattct atcgcagtat ataccatcct tgcggacggt agcttagagt tattagaaat
     3361 cgttccaacg catggtcaga ctccacgtga ttttgatttg acacccgacc aaaaatttct
     3421 cattgttgtc catcaagact ctgacaatgc aactgtcttt aaacgtaatt gtgacaatgg
     3481 tcgtctagca gaactctcca acgacttcca tgttcccgaa gcagtctgca tccgttttgc
     3541 tccttaaaac accataaaaa atgaacttgg tattttcaag ttcatttttt cttatagtct
     3601 atttccgaca ttaatacggt taatagcacg ttgcaaagca atcttagcac gacgttcttg
     3661 gtcaatcaaa tgtttgtctt gtgcttcttc aattgcacgt tctgcacgaa gtttggcacg
     3721 ttctgcacga ctgatatcga tatcacgagc acgttctgca gagtcagcga cgattgtgat
     3781 catatcattg gcaatttcaa taacgccacc gtttactgca atccagttca cgtgatcttt
     3841 atcatcgata cgttttacct ttacttcatc aactgctaaa accgcaatca tattttcatg
     3901 tcgtggcaag atccccatct caccatccag agttcgaacc gatacatagc tggcatggtg
     3961 atcatagacg agaccatctg gtgtcacgat ctggacagtt aactgagcca tagatcacct
     4021 cttaaaatcc cattttttca gcttttgcaa tcacatcttc gatagaacct acaccacgga
     4081 aggcatcttc tggcaagtgg tcgtatttac catcaaggat ttccttaaag ccacgtacag
     4141 tttcagcaac tggaacataa gaacctggct gaccagtaaa ttgttccgca acgttgaagt
     4201 tttgtgacaa gaagaactgg atacgacggg cgcgagcaac caaggtcttt tcttcatcag
     4261 aaagctcatc cataccaagg atagcaatga tatcttgcaa ttcatggtaa cgttgaagga
     4321 cacgttttac ttcagcagca actgcatagt gctcttctcc aacgatttca ggtgccaagg
     4381 cacgtgagct tgaagcaagt gggtcaacgg ctgggtagat acccaattgt accaacttac
     4441 gttccaagtt tgttgttgaa tccaagtgag cgaaggctgt tgctggcgct gggtcagtat
     4501 agtcatccgc tggcacatag atagcctgga tagaggttac agaacccttc ttggttgatg
     4561 tgatacgttc ttgcaattga cccatttccg tagcaagtgt tggttggtaa ccaacggctg
     4621 atggcatacg acccaaaagg gcagatactt ctgaaccagc ctgagtgaaa cggaagatat
     4681 tatcgataaa gagaagcacg tcttggcctt ccacatcacg gaagtattca gcgattgtca
     4741 aaccagtaag ggcaacacgc atacgtgctc ctggtggctc attcatctga ccaaagacca
     4801 tggctgtttt ctcgataacg cctgattctt tcatttccca gtaaaggtca ttcccctcac
     4861 gagtacgttc cccaacacca gcaaatactg aaataccacc gtgctcttgg gcaatgttgt
     4921 gaatcaattc ttggattaag acagttttac caactccggc accaccgaaa agtccaactt
     4981 taccaccttt aaggtaaggg gcaagaaggt caataacctt gatccctgtt tcaaggattt
     5041 cagaagaggt agacaactca tcaaaagttg gagctttttt atgaattggc tgacgctctg
     5101 cgtcttctgt aaaaggagct tccaagtcaa tggtatctcc caaaacgttg aagacacgtc
     5161 ccaaagtttc tttacctact ggtacagaga ttggacgacc tgtgtccaat acttccattc
     5221 cacgagtcaa cccatctgtt gattccatgg cgatagtacg aaccatacca tctcctaact
     5281 ccaaggctac ttcaaggacg atttttgttt ttctttcgtc atttttgtag acgacaagtg
     5341 cattgttaat ctcaggaagt ttttcccctg ctgcaaacaa aacgtctaca acgggaccga
     5401 taacctgagc aattttacct gaactcatct ccttctccta ttctatataa gatactgtcg
     5461 gttcctagct caactaggtc ctaagttcat tttcatacga gctggactag agcctattct
     5521 aaggcactag cacctgctac gatttctgta atttcttgtg taatcgccgc ctgtctggca
     5581 cggttatact gaattgtcaa atcattgatg actttcttag cattatctgt cgctgtttgc
     5641 atggctgtca tgcccgcagc attctcagct gtcttggcat cgataatggc accgtaaatc
     5701 atactttctg caaactgagg caacaactgc tccagaattt cttctcggct ggtttccaat
     5761 tcaaaagtca agctgtactc ttcatccgct tcatttggat ccaagtcaac aatcggaagc
     5821 atttgttcca cacgcatttg actggttagc gtattgacat ggtggttgta gcaaacataa
     5881 agctcatcaa agagttcatt ttggtacatt tcaacagttt ttgaaataat cttacgaact
     5941 tgatcaaagc taggttggtc tgacaagcca cgtaattcat aaagtggttg aataccgcga
     6001 gccttaaaga aatcagctcc catcccaccg atacagatca tttcaaaacc tttaccgtct
     6061 gggtggtatt cttctttcaa ctccataaca gctttcaaaa tagaggaatt ataacctcca
     6121 accaaaccgc ggtctgaagt gataacgata tagcctgtct tcttcacaga acggctaatc
     6181 aacatcggat tagttgaagc accagctcca ttaccatgaa ggatatctgt caaaagttta
     6241 cgcactttct gagcgtaaac ttggaagttg cgagcagctt cttcagaacg acctagctta
     6301 gcagccgata ccatttgcat ggcattagtg atttgactcg tattttttgt tgaggcgatt
     6361 tttgttttaa tatcatttag agatactgcc atctgacacc tctattctta ttggaagcta
     6421 gattgattga gaaactctgt aatcgcagca tccaagactg cttcttctgg caagtctttt
     6481 gtatcacgaa tggtttccaa aatctctgga tgttgagcat caaagaaggc atggaactct
     6541 tcctcgaaac gaacaatatc atctactgga acagtatcca agaaaccatg tgtcaaagca
     6601 taaagaatgg ttacttgttt ctcaacaggt aatggtttgt gaacaggttg tttcaagacc
     6661 tcaacggtac gacgtccacg gttcaactta gcctgtgttg ctgcgtccaa gtcagaacca
     6721 aacttagtaa aggcttccaa ctcacggtat gaagcaaggt cgatacgaag tgtaccagca
     6781 accttcttca tggctttgat ttgtgcagaa ccacctacac gagatacaga tgaacccgca
     6841 tcgatggctg gacgaatacc tgcattgaag aggccatcgc caaggaagat ttgtccatca
     6901 gtgatagaaa tcacgttggt tgcgatatag gctgagatat ctcctgcttg tgtctcgata
     6961 aatggtaggg ctgtaattga tccaccacca agttcatcag aaactttagc tgagcgctca
     7021 agcaaacggc tgtggagata gaaaacatcc cctgggaagg cttcacgacc tggaggacga
     7081 cgaagcaaga gcgacagttc acgataagct accgcttgtt ttgatagatc atcgtataca
     7141 atcaaaacat gcttaccttg atacataaat tcttccgcca tagcaacccc agcataagga
     7201 gctaggaaga gcaatggaga tggttgtgaa gcagaggctg tcacaacgat tgtgtagtcc
     7261 aaggcaccgt actgacgaag tgtttctact tgcgtacgaa ctgttgattc tttttgtcca
     7321 atcgcgacgt agatacagat catatcttga tctttttggt tcaagattgt atcaatcgca
     7381 atggttgttt tccctgtctg acggtcaccg ataatcaact cacgttgacc acgaccaatc
     7441 ggtacaaggg cgtcaatagc tttcaaacca gtttgcaatg gttctgaaac agacttacgt
     7501 tgcataacac caggagctgg tgcttctact ggacgagttt tatcagtgtg gatttctcca
     7561 agaccgtcaa ctggacgacc aagcggatcc acaacacgac caatcagact ttcacctaca
     7621 gggacttcca tgattttccc tgtacggcgg attgtatcgc cttcacggat atctgtaaag
     7681 tcacctagga tgataatacc aacgtctgtt gactccaagt tttgagccat accataagag
     7741 ccgttttcaa aattcaacaa ctctccactc atgacatttt caaggccgtg agcacgcgcg
     7801 ataccgtccc cgatataggt tacaacacct gtttcagtca catcaaaatt gggtttgaaa
     7861 ttttcaattt gttgcttaat taaagcgctg atttcttgtg cgttaattgc caaaagaaca
     7921 ccactttcta tttcaaattt tctttaacaa ctttaagttg ttgtttaata ctcacatcaa
     7981 ttgtcttgtg attggcaaaa atgacaaaac caccaatgag actttcatcg atttgttctt
     8041 ttacactcct tactttcaga gacatttttt tctcaatcaa agggagcaaa cgagtcttct
     8101 gttcatcagt tagaggatga gcagacgtaa tcgtcacttc aaatcgattt gtttcttttt
     8161 caagtcggtt caagcaatct acaagcacat cataaaaaag atttgctctg tgattgtagg
     8221 ccagaacctg gataaagttt tgtaataaag gcgacacaga atcttggaaa aaagcaattg
     8281 ttttttcctt atccgactcg tctactgcca cttgttttaa aaaagaaggc agacctgttt
     8341 tttcaacaac ttgcttgatt tgagtcaagt ctgaaaagat acggtcttct tctccttttt
     8401 caagtaccaa ttggacaaaa ggcatgctgt atttttcaat tacctttact gttttcttgt
     8461 ccattaagct tctcctagct gatcgatata ctgatcaatg agtgctttat gggcatgact
     8521 gtcaaggttt tgtgagatga ttttaccagc taagctgatg gtcaaatctg cgacctcacc
     8581 cttaacactc tgtaaagctt ctactttatt ttgagcaatt tcttgattgg ctttttcttt
     8641 taagtgtcct gcttctagtt tagcatctgc taagatatta gccttacttt gctcagctgt
     8701 ttcctttgca ttttcaatga ttgtcttagc ttctttacgg ctaccagcca attcatcttc
     8761 gcgtttttga gccaatactt ctgctttttg acgggcttct tcagctctgt caatatctga
     8821 agcaattttt tcagctcttt cttcgaaaat gcctgtaata ttagaccatg caaatttttt
     8881 aatcaagact agcaaaagaa taaaagagcc agtgattaaa ataaaattac caattaattc
     8941 acctactgtt acgtgcatca gttactcctt tctattcctc ttcaatatta atcttattcc
     9001 ctaaatacac agatgtcaaa agagtaaaaa cataagcttg gatgcaggaa ataaagacag
     9061 aaaatgcagt ccaagccaaa ttagctccaa aggctactgg ataccaataa atagcttggt
     9121 gggaaagaag aagtaacaaa ctcgtcatga cctctcctgc aaagatattc ccaaaaatcc
     9181 gcaaagccaa agataagaag tttgtaaatt cttccaagat attcatcggt atgacaaaaa
     9241 caggactcat aaaagatttt atactttttt taaatccacg acgacgaacg ctttctatat
     9301 gtgtcaacaa aatgacaaga aaagataagg ttaagtcata ctgtaaatta gcggttggcg
     9361 aactccacca gttagtccca tcgatcgttt gaagctttgt cattaagcca aggttattgg
     9421 caatcaccat gaaaaggaat aaacaaagga aaaagagtga gtaatctttc atgtagcgcg
     9481 aaccaatgtt aggttctgta aatccaataa caaagtcata gacatactca agtacatttt
     9541 gctttccttt gggtttcaag gtcatattgc ggcttgccca ataaataaag acaaaaataa
     9601 ctcccacaat caacaaagtc atggctaaca tagtcagatt gaagataaca ggaccaatag
     9661 agatgattgg attaatactt tcttccatct aaaatcctcc cttttcttct cgttccatgt
     9721 atttatttga taataaatga gaagacaaga gttacaaaga aagttccttc aataaaggca
     9781 acacctaaaa acatcaaact acgaaactca gaaagcatat ctggttggcg tgctactgat
     9841 ttaaacagtc cattcatcaa taaaccttca ccgacagata cgcccataca ggcaatacat
     9901 aagcctaaaa atgttaaatt cataacaaat tctcctttaa aataaaattt acttacttag
     9961 tgtagtccta aaatttaaat ttgtcaactt ttaaccgcta ttggaagcgt ttaataaaaa
    10021 ttatttccat tttgctaaat ttcaagttca agttagccat ccagaagtct tctctgggtg
    10081 acttgtagtc caagcatttt ttaggatagt tgttaatcca cttttcgatg aatgcgactt
    10141 ctttgggagt cattttcttg gttcccttag gtaactatct acgaatgagc ctgttgtgat
    10201 tctcattagt tcccctttcc caagaggcat aggggtgcgc ataatagatg tgctcctcag
    10261 aaaatatatc aaacaagcga ttgaattccg ttccattatc tgccgtgatg gaaagaatct
    10321 tgtgttgttt taagatgagt tttagagcct gattgaccac ctcagcactt ttatttggaa
    10381 tcaatcggat gatctgatgt ctactctttc gatccgtcaa gacaatcaag cagtagtttt
    10441 tcgatctcgt aagtagaacc gtatcaatct cataatgccc attctccaag cgaagattga
    10501 tagcttcagg ccgctgttcg atggattgac cagcaggttt aaagttggtg ctagcctgtt
    10561 tcttaagcgc ttttcctttt ctagggtaaa gcaaatcctg cttgcttaac cccaattttc
    10621 catgatgaat ccaatagtaa atggttgaaa ttcccacgtt aaccccttta gccataacca
    10681 tcatttcagg cgaaaatttt tggttatgat agtggagaat cttttccttt agttccttgg
    10741 tcaagcttga tttcttgacc gagcgcttgc gattgttttc ataagactgt tgagcgtagt
    10801 cggcagaata aacctctttg aagcgccctt ttccaagaca ttgtcggact gtcccacgct
    10861 tgatttcagt gtgatagttt gaggagcttt tccaagtaga gaggcaattt ctctatttga
    10921 ttttccttct tttttccatc tttcgattaa gcgacggcta tcgattgtca aatgtttggc
    10981 ttttgtagta taattgtctt gcatctctgt gcctttcttg tgtttgtggt tgaacaacaa
    11041 gtataacaca gaggtgcttt cttatgccta caagagcttt cattatttcc attttctttt
    11101 ggatttcact ctattctgaa aaacttgtgt atatttactg aagctagcaa gtcttacctg
    11161 taaatttaat gaaagcaaca caaaatccga gaggggaatc tcggattaat agatagagag
    11221 tttttagttt aaataaattg tttaaaatat caacaacatc acttcttttc ttaacctgat
    11281 aagtcttgat tcctaatttt ggggctacga ttatattgtc ctcaatatcg tctagaaaga
    11341 cacaatttct aggttataac tggtatttat cgatagttac tcatatacat cagtccacct
    11401 ccatacttat gtgcgagcct ctctttgtat tatacctcca tactcacctt acagattctt
    11461 ttggtaataa tatctttgcc taatgtagag acagtcttgc aaagaaaaaa cttccttgta
    11521 gccatgtttc tgataaaagt ccggtgcctg gaactggtaa gtattgacaa aggcaaaaca
    11581 acaatttcga ttcttagctt cactttctgc ctgttgcaat agttttgaac cgattccttg
    11641 ccctcgcagt tcctctttta caaacaaata ctcgatttct agccaatttc caaaagtctc
    11701 tgctatcaaa cctgccagga gattgccctt ttcatcttcg acataaagat taagtggctc
    11761 actttcagcc tcttctcttt ttgaacggtt ataaacacga atcagattcc ctatttcttg
    11821 cgatttatgt gattccttat tttccaatct aaagtatagt gaaatgaaat aaaacatgcg
    11881 caaatcgatt aaggaattta atctaatttc taacaatgtc ttagaaatca aagtgtacta
    11941 ttttaacttc aatgcactat acatctaata ctcaataaaa atcaaagagc aaactaggaa
    12001 actagccgca ggttgctcaa aacactgttt tgaggttgta gatagaactg acgaagtcag
    12061 ctcaaaacat agttttgagg ttgtagatga aactgacgaa gtcggctcaa aacatggttt
    12121 tgaggttgta gatgaaactg acgaagtcag ctcaaaacat agttttgagg ttgtagatga
    12181 aactgacgaa gttagctcaa aacactgttt tgaggttgta gatgaaactg acaaagtcag
    12241 taaccataca tacggcaagg cgacgctgac gtggtttgaa gagattttcg aagagtagca
    12301 aaatggaaaa aggagtgagt gaagcacatc gcctccccac tcctttttct gtttttaggc
    12361 tgttttttca accttcaaga tttttacatc atagctacca acaggcgttt caatggttgc
    12421 tgtatcacct gttttcttgc caatcaaggc ctgcccaatt gggctttcat ttgaaacctt
    12481 acctacaaag gcatctgcac cagctgaacc tacgataata taaacttctt cttcgtcctc
    12541 accaatttct tggatggtga ctgttttacc aatcgctact tcgtcctggg caactgcgtc
    12601 gctattgacg atttcagcat agcggatttt tgtttctaag ctagagattt gtccttcgac
    12661 aaaggcttgt tcatccttag ctgcttcgta ctcactgttt tctgaaaggt caccgtatga
    12721 acgggcaatc ttaatgcgtt ctaccacttc tggtcgacga accaatttca attcttctaa
    12781 ttctttttca agtttttcct tttcctcaag ggtcatagga tatgtttttt ctgccatttt
    12841 tctcaacttt cttctgataa tattttctaa agaaaattat gtgaagtatc acataatttt
    12901 agtttgttta gtttaatttg ctgttgacat gttcagcgac attgcggtcg tggtcttctt
    12961 gattgttagc atagtagacc ttgccttctg tgacatctgc tacaaagtag aggttatcgc
    13021 tcttagtttg attgatgctt gactcaatcg catccagact tggactatcg actggaccag
    13081 gcatgagacc tacattttta taaacattat aaggtgaatc aatgttggta tcaatcgcaa
    13141 catcctcagc tagactgata ttttgcccca gttttccttg ggcatacaag attgcaatat
    13201 tactttgaag tggcatatca cgattcaaac gattgtagaa tacacctgca atgagcttac
    13261 gatcttctgt cttggcacct tctttttcga ccaaggaagc aatggtcaac aactcattga
    13321 cagtcaagtt tttagatttg atagtactat agtaaggaga taggttctta tccatagcag
    13381 ctaacatctc atcaatcaag ctctcaatag ttgtgctttc cttgatagag tatgtagctg
    13441 ggaaaaggta tccttccaaa cgataacgcg caccgctgtc ttttacaggc aaactttcca
    13501 gtaaagtagg atatttcgct actgcttgac tgataaacgt ctcatcttga actttagcca
    13561 agaaagcctc cgctgtcaaa gactctttga agtcaccttg caattgaccc acagcttgag
    13621 caatctgatc caaggtataa ccttctggaa ttgtcaaagt cgcaagtaca ggttcttgcg
    13681 gttcatctgt tccacctttt tgcaactctt tgagtaagtc ttctgtactc atactctttt
    13741 gcaaattgta gtaacctgct ttcaagtcgg tataattttt atacttggca taaaaactaa
    13801 aaatcagacc atgctttacc aaaccagctt tttcaagcgt cgtaccgatt tcttgaacgt
    13861 ttgaaccttc tggaattcca accgtcacat atttcttaga attagcatcg ataggtaata
    13921 aggaatctag cacgtactgg taaccaaagt aaccacctgc tgagagcaag gcaaggaata
    13981 caaggaatga aatcacaaaa gctttcacat gtgacttctt ctctttctta ggcttaacgg
    14041 gttttgctcc ttctctacgg ctacgacgtg atgtatctct gatgatatcc actgtttctg
    14101 tagcaggcgt aggtgtttct ggacctgctt gttctgcttt tttctctgcc gtcgtatagg
    14161 aaacagctac ccttgttggg gtttcattgt attctctttc aagtttctta ggtctaacag
    14221 gacctggacc tggtcttgat ccactttctt ccgctggaga agaaggtaca tcttgacttg
    14281 gatgacttgg aacaccagga gtttctcttt gaatctcatc tgctggagaa gctggtacac
    14341 cttgacttgg gtgagtaggc acggtaggag cttttctcat aatctcctct accgttgaca
    14401 aggaatcagc catgagttct tcagttgaag gttcatttgc aggagtgcga actactgcct
    14461 catcttcttt cagaacttca tcatagcctt ttactttttc taaatctctc agaatctgct
    14521 ctttaaagct taatttctct tcttctcttg acttttcact caaaagtttt tcctccttgt
    14581 tgataatcca taatattata tcttaaaagt ccaaaaaaag caatctatga tacttttcct
    14641 aacttatttt ttcatttccc agaccatatc ataccatgtt tcccctgcaa aggttgactg
    14701 ggactggcct tcgttgacaa atccatgttt ttcatagtag gcgatgagat agtcatgaca
    14761 ggttagatta atgccatctc tctcatcttc aagagcaact tctttcaagg ctgtcagcaa
    14821 tttctggccc agtccgagtc cctgtgcctc cttggcaata gacagacagg tcacagagat
    14881 ataaccacca ggctcatgac tatagtcttt tatttcttct gtaaaagact ggtcttgcag
    14941 atggcggtgc aggccaactg gtccttcgat ataacccatg attcttcctt ctttttcagc
    15001 aaccagaaaa gaggtctgaa tttctctcaa atgtgcttca aagacagaag gaggaatggc
    15061 ttcttcgacc gaaaaatttt caaattcaag ttcaacaatc cgatccaaat cttctaatct
    15121 tgcttgtctg attttcattg ttcctccaga taaaagggat taaaccaaat catactatag
    15181 ccctggctag ttgcatagag caaagttgct tcttcatcaa caaaaccgtt catttcaaaa
    15241 taggaaagca gctcatcagg actctccaaa cgaatccctt tgtaatccag ctcaactgcc
    15301 acctctttca aggctgcaag aagaagtgtt cccaggccct gtctctgatg gtcaaactcg
    15361 atgactaaag aatgtacttt tagacattgc ggattgtctg actggggact tgataaaata
    15421 tagcctaaaa gttgattttc atccctagct agaagaaagg tatccgcaca cttacggata
    15481 ctttcttcta aaatatggga aagttgctgc ttttcagctg gaaaagacga ggtctgaagt
    15541 gcccctatct caggcaaatc agacttgctt gcctgaatga tcttaattgg aatttccatg
    15601 ggaacatcct attgaacatt gcttgtcaag ttagacaaga gacgctcaaa tgagtattca
    15661 taggtttgga tgtctcctgc tcccataaag acgtaaacag cattgtcatg gtctaggagt
    15721 ggagaaacat tttcaacagt aatcacttgg tgttttttgt tgattttgtt ggctaggtct
    15781 tctaccttaa cgtcaccatg atctacttca cgagccgagc cataaatttg cgctagataa
    15841 acagcatctg cttggtttaa agcatgggca aagtcgtcca acaaggcaat ggttcttgta
    15901 aaggtatgcg gttgaaagac tgctacaatt tccttgcttg ggtatttctg acgagccgca
    15961 tccaaggtcg caataatttc tgttggatgg tgggcaaagt catcgataat cactgtatca
    16021 ttgacaattt tctcagtgaa acgacgttta acaccggcaa atgttttcaa gtgctcacgc
    16081 accaagttca aatcaaatcc tgctgtgtaa agaagaccaa taacggctgt cgcattcatg
    16141 atattgtgac gaccaaaggt tggaatgtgg aattgcccca agttttgtcc acggaaatga
    16201 acggtgaagg ttgaaccagt tattgaacga agaagatcac tagctacaaa gtcattgcct
    16261 tcagcttcaa aaccataata ataaattggt gcatcagacg taatcttacg caattcagca
    16321 tcttcaccat agacaaaaag acccttggtg atttgtttgg catagtcgtt aaaggcatta
    16381 aaaacatcct cgagacttgt gaaataatct ggatggtcaa agtcaatgtt ggtgataata
    16441 gagtattctg ggtggtaagg catgaagtga cgctcatatt cgtcagattc aaagacaaaa
    16501 tatttggcat tggccgaacc acgacctgtc ccatctccaa tcaagaagct ggtatctgta
    16561 atgtgagaca agacatgaga caacatacct gtcgttgaag tttttccatg tgctcctgct
    16621 actcccatgc taacaaagtc acgcataaag ctacctagaa actcatggta acgtttgtag
    16681 ctgataccat tttggtccgc ataggcaatt tcgacgttgt tatctggacg aaaggcattt
    16741 ccagcgataa tttccatatc accgtctaga tttttttcat caaaaggaag aatggtaatt
    16801 cctgcctgct caagaccgcg ttgggtaaag tagtactttt caacatctga tccctgaacc
    16861 ttgtgcccca tctggtgcaa catcaaggcc aaggcactca tccctgatcc cttaattccg
    16921 ataaaatgat atgtctttga catgttttct cccctattct gtcattctgg tcagattcaa
    16981 ctcttgggca acccgacgtt cttgttctgt ttgtttactt tttttattgt agatttggct
    17041 cttctttaga aaatcataat tgtttttctt tggagcaggt gctgacactt cttcattctt
    17101 ggtagggata gaatgaactt cttccgccaa gatataatga gactgggtca atttttggct
    17161 atatttgaca aattcaccag gattttcctt ttggaaagga gctgtcggtt gattgccctg
    17221 tctaactaga ctgggctgag aatgacgtct cgcaaggctg aaatcctgag ttaggtagtt
    17281 agcagagcgt ttctttttca agtccgcacg cgcttcttca cgcgccacct ccgcatagct
    17341 ctttccttct tttttaaccc ctaaaggagc ctttttaggt ttttcgactt gcttttcaat
    17401 cggttttact ggtttttctt cagcaatagg agcccattct aaataatttt tatctcgata
    17461 ctcacccttg atattactga tcagatcaga ctcatcatag agattcatga ctggcatttc
    17521 agtcaacatg acctcgtcat ctgacaccaa tggaaatcgt tcttgtttca ttttctattt
    17581 cctttcaaca cttcattata gcgtattgtc ttgatttttc aagtgctggc ttcagaaatt
    17641 cccaaaattt ctctaatttc tgctagggtc agactaccac gtgactctgt gccgtccaat
    17701 acttgtgaca ccagatgttt cttttgttct tggagttcct gaattttttc ttcaatggtt
    17761 cccttggtca ccaagcgata gacctcaacc gtttcttcct gacccatccg atgggcacgg
    17821 ccaatggctt gcgcttccac cgcaggattc caccaaaggt caaccaagat cactgtatct
    17881 gcacctgtca ggttcagacc gaccccacca gccttgaggg aaatcagaaa ggcatctctt
    17941 tctccttggt taaaggcctt ggtcatgtct tgtctttcct tggctggggt tgaacccgta
    18001 attttaaagg aagtcaggcc caagtctggc agttcttgtt caattttttc caacattccc
    18061 ttgaactgag agaaaatcaa gacacggtgt ccgccgtctg ccacctgtac cagtaggtct
    18121 cggagactat ctagtttgcc gctggctccc tgataatctt ccataaacag ggcaggagtg
    18181 tcacatattt gacgcaagcg catcaaacca gataaaattt ccacacgact tcgctgaaat
    18241 tcctgttctg acacttgagc cagatggtct cgcatctgtt gtaactgggc aaggtaaata
    18301 gccttttgct ggtcttccag ttcattttta taaaccacct caatcaagtc tggcaattca
    18361 gtcagaactt cttctttctt gcgtcgcatc acgaaaggct tgataaactg agccactcgc
    18421 tctgctggca atttcataaa ttctttcttg cttggcaaaa gtccaggcat gacgatttgg
    18481 aaaatagacc acaactcacc cagatggttt tcaatcggag ttcctgacaa ggcaaagacc
    18541 gacggcacca caaattgtct caaggtctgg gcaatcttgg tctgggcatt tttcatgacc
    18601 tgagcctcat ctaagaaaag gaagtcaaag gccatccctt gataaaactc actgtcctga
    18661 cggaaggtgg catagctagt cacatagatt tgatggctct cggcaagaat ctcctcacga
    18721 cttgctttca aaccatgaac aacagtcaca tccaactgtg gagcaaattt ctgaaactca
    18781 tctgcccagt tgtaaatcaa acccgacgga gcgagaatca aaacccgact ttcttttgtc
    18841 acttgactag tcaaaaaagc aatggtctga agggttttcc caagtcccat atcatcagcc
    18901 aaaatcccac caaaaccata atgatggagc atctgcaacc agccaattcc cttttcctga
    18961 taatctcgca agtcagcctt gacctgagtt gcttgcaaag gaaagtcctc tggatgcgtc
    19021 aaatcctggg ccagattctg gaattcttgt gaaaaagaaa cacggtctcg cccttcaaag
    19081 agatgagcta aactgtaggc caaggatttc cgagcctgca aggtcccatc ttttaattca
    19141 aattgcccca gttcctgtag attttggcga attttcttgg tttcttcatc gaaaaagtaa
    19201 acttgattag acgaatcaat ataaaaatcc tgattggcaa ccaaggcctg catggcttgg
    19261 tcgatttcct cctggacaat attttgaaaa tcaaactgga tttccaagag acctcccttg
    19321 gaggcaatct gcacctgagg actcgctagg ctataaagct cttctagttt atctgatagg
    19381 tcaacatgcc cgagtttttc aaagactgga atgatatcat gaaaaaaatg atagacagac
    19441 tccgctttta aggcctgacg ccaagattga aaatcggcct caaagcccgc agccaaacag
    19501 acttggaaaa ttctttcttc taagtctgcg tcacttgaaa agggtaattc ttctagctct
    19561 tgtcggctag atacctgtct atttccataa tcaaactgaa tttctaaacg aatccgatta
    19621 tcttcttccc tgtcaaagta aaaagagggc gcaaaagttt tgatttgtag acgttctgga
    19681 gctgaaacgg tgcccatctg gataaaaaga gtcagacagg aggccaattt gtctcgatca
    19741 ctgctatcaa attgcaggta tttctttcct tgttgaccca caggtaacgc tttaatttcc
    19801 ttgagaagac gcatctgctg gtctgttaaa aaataaacct gacctttatg gaaaagtact
    19861 gctccctgat aaaagacatt gaccctagga ctctcactga tttccatttc aaaataatcc
    19921 gagtattctg ttactgtaaa ggcaaataga ttggcatcag catgcatatc ctgaaaaagc
    19981 agggtttggt agctatccac ttgatggtca aattgaaaat ggggcaaggc catcagtaaa
    20041 ttcacaccct gctcaaaaaa ggtcagaggg aaaaagaggt gccgaccttg gttttggaaa
    20101 aagaggtctg gaaccagccc ttcctccgtt agtccgtgca agaaagtcaa aagttcttgg
    20161 ctggcatcat caaaggcttc ccaagaaaga gactcctcat aaatcttgcc aatcatatac
    20221 gactttctct gctcgacaat ccttaaaaaa agtggaatat cccgaatgac atagtatttt
    20281 tggctattga tttggccgat tctcagagtc cacaagatat gattggttcc tgcttccacc
    20341 tgacccacag ctgataactc ataggcgcat tctgattttg gagataaaat tcgatccaaa
    20401 aacttgccac ccaaggtcac cttggtttca acagcctctt tttcttcatg accttcttcc
    20461 agactccaca agatttcctg accacgctca tcatttttca gaaaatgctc tagcgctgcc
    20521 aaatgcacac agtagcccct cttttgaaaa aaatcacagg cacaaaaaac caaatcatcc
    20581 tctaaactat agcgcagttc ttcttctgca acgcgagcgt agagccgatt gttcttttcc
    20641 ttgatgatat caaccttacc agtttcataa agggcaacac cttcgatacg aattttcccc
    20701 ggaatcaatt tagccatatt ttcaccttta ccttatcttt ttattatacc atattttcgc
    20761 ctatgaaaat agccttctag gaagactttt ctcctagaag gctggatttt taacgtttgg
    20821 caaaagtagc cacaatccgc tgacagactt cttgcaacag agatttgggc atagctatat
    20881 tgatgcgggc atggagactt ccttcctctc caaaatccaa accacggttg aggataacct
    20941 tggcttcatt tctcaacaac tcttgcaatg tttcatcagt caggtcataa gctgaaaagt
    21001 caagccaaat caagtaggta ccttgcggtt tcatgacctt gattttagtc tcttttccaa
    21061 atagatccat cacataattg atgtggtctt caaagacttg cttgagttcc tctagccaat
    21121 ctttaccgta tcgataggca gcttctgtcg ccaaataacc caagcctgaa atttcatgct
    21181 gattattggc caacaggcgt ttctggaaag ccagtctcaa cttaggattt tcaatgactg
    21241 cataggaatt ttttgttcca gcaatattaa atgttttagt ggcactgctc aagacgatag
    21301 caaaattttt gaaggcagga ttgatggtat tgaaagactg gtgtttgtga ccaaagaggg
    21361 tcaaatcttg gtgaatctca tccgaaacta acaaaacacc gtgtttttgg cagagttggc
    21421 caatcttctc caacacttct ttttcccaaa cacgtccacc aggattgtga gggttgcaaa
    21481 gaacatagag tttaacctcc tcttccacca aatccttttc aagttggtca aagtcaatct
    21541 caaacagact atccttttcc actaaggaat tagtaatcaa tctacgatta ttcaacttga
    21601 cactgcgagc aaagggtggg tagacaggcg tgttaattaa aaccgcctcg ccttcttttg
    21661 taaaggtttg aatagctgtt gagatggctg gtaccacacc ctcgataaag acaagagcct
    21721 ctttgtcaaa gttgtaaccg tattgtgtag cttcccactt ttgaacttcc ttaattaagt
    21781 cttcactggc ataggtataa ccataaacca gttggtctgc gtaagtttgc acggcttggc
    21841 ggatttcagg caagaccaca aagtccatat ccgctatcca agctggtaga acttcactat
    21901 ccgtttctgt ttctttccat ttataggtat ggtgccctaa acggttgggc aggcttgtaa
    21961 aatcatattt tcccatcttt gtcttatcct tctatggctt ggcgcaaatc tgcaatcaaa
    22021 tctctagcat cctcaatccc aatagacaaa cgcaagaggt catctgtcaa accataagaa
    22081 tggcgtacct ctgctggaat atcagcatga gtttgagtcg ttggataagt aataagactt
    22141 tccactccac ccaaactttc cgcaaaagag aagaccttga gactgttcaa aatatgagga
    22201 atgcgtgttt catcggctac tttaaaggaa atcatgcctc cacgaccagt gtagagaact
    22261 tccttaactg ctggagaatc cttcaaaaag gcaaccactt cttgggcgtt agctgttgag
    22321 cgctccatac gaagagacaa ggtcttgaga ccacgaagca actggtagct gtcaaatgga
    22381 gacaagactg cccctgttgt attaagattg taaaaaagct tctcgtatag ttctaaacta
    22441 ttggtcacaa ccactccagc caagacatca ttgtggcctg ctagatactt ggttgctgaa
    22501 tggagaacga tatctgctcc atcttcaatc ggacgttggt agatagggct atagaaggta
    22561 ttgtccacca ccactttggc acccttagca tgagccaatt ttgctagttt ttcgatatca
    22621 aattccaaca tcaagggatt ggttggggtt tcgatataga gaacatccac atccttttct
    22681 aactcggcaa tcaactcttc ttctgtattg gcataggtaa aatggaaatg accttcctgc
    22741 tccacttggt taaaccagcg aaaagaacca ccgtaaagat cacgcactgc caagacctta
    22801 cttcctactg gaaagacgct aaaggccagt acaatagctg acatccctga gctagtcgct
    22861 agggcatagt ctgctgactc aatagccgcc aagacttcct cagccttact acgagttgga
    22921 tttttagtgc gcgtatagtc aaacccagta gatcgaccaa actctggatg ctgataggtc
    22981 gttgaaaaat gaagtggtgt caccaaagca cctgttgcct catcagactt gatccctgct
    23041 tgtgctaaaa ttgtgttaat gtgtaattcc ttgctcatac aattcctcca aatctatagt
    23101 aactattgta ccacttattt tgtatccttc gttttcttgt tttcaagagc tagttatagt
    23161 ttcaaactat ataaaaaggg agtttttcct gctcccttta atagactata aaatggtgaa
    23221 tctcaaaaga caccttcact ctatcatttg ctcctgcaca aaacgagcat aacgctcatg
    23281 attttccagt agttccttat gagttcctga gccagtgatt ttcccctcct ctaagaagaa
    23341 aatacaatcc acatctttta ccgttgacaa acgatgcgct ataatcacaa ccgtcttctc
    23401 ctttagtaca gaatagaggc tactgataat cgcatactca gaatccgcat caagattagc
    23461 agtggcttca tcaaatataa gaatttcagc atcttttaag taggctctag ctatttgaag
    23521 tctttggctt cgcccccctg acaagagtcg tccgcgttca ccaacttcag tatctagtcc
    23581 ctctttcatg gagcgaatct catcacctag tgatactaag tctagcactt tcatcaattc
    23641 atcatcagtt actaagcgat tcaaaccgag acaaagattg tcacgaatac tgccagataa
    23701 gactgcatta ttttgtgaaa cccaagcgat tttacttctc cattctttta agttaaaatc
    23761 atatatactt gattgctcca ttagaatatc tcctgaaagc ggtttataaa accgctctaa
    23821 caaacgcaca atcgttgatt ttcctgatcc agatggtcca acaaaagcaa ttttttgccc
    23881 cttgaaaatt gaacaagtaa tatcctttaa gacaggtcga ttttcatcat aaccaaaata
    23941 gacatggtta aaattcaacc ctcgtcctga taccgatttt cctccctcaa atttttcttt
    24001 aggaactgca agcaagttct ccagtgcaac tgaagatccc ttgctcctag aataaacagt
    24061 tacaaaatta gctatattac taataggatt aagtaattga aagaggtaaa tcaaaaacga
    24121 aaccaaggtt cccacagata tatatcctgc gctgacccga taacccccat aggttagcat
    24181 cacagctata gtcgcaaaga taaataagag agcaaacggg gtctcaaaag aagtaaccct
    24241 atctgatttc agtgaattgt tttgtaccct ttcaatacaa ttatccaaaa catcctgtac
    24301 acttttctct gcttggttag tcttaattaa ttcatgttct tgaatctttt cagtcaattg
    24361 ccctgttaaa tttcctcctg taaacgacga ctatactttt cactgatatt ggaaaggggc
    24421 aagataataa acatcataca aggaagagtg atgaataaaa gtagagaaag attccaatca
    24481 agactaaata agactacaat ggaaccaagt accataacta aactcagaat aatatttggg
    24541 aaagtcgtaa ttaaaaactc acgaatgaca ctcgtgtcat tgacaatggc agaagtcaac
    24601 tccccacttt ggctcttatc aaagaaggat ttctctacat aaatcaaccc ctctatcact
    24661 tttttcctga tttttgctat ctttttttca cccgattgac taaacagata gtaaccaata
    24721 gaagaaaaca aggcttgacc aataaaaatc aaaaacgatt gaaatacttt ggagcctata
    24781 ttttcaatag aactcccatc tattaaatcc tttaagataa ggggaagcaa caaagcaagt
    24841 agactagaca gaacaagtaa gaaactcccc ataatcacct tagtatctac tcttaataat
    24901 tttaatttca taaatactcc ttataatatt tcaacggata aagtcgggaa taactcaatt
    24961 tgaggataaa atctaataaa tcttcctata acaaaacgca taacatctag gattttatat
    25021 acctgatatt atgcgttttt aagcacaaag acttcttaca caaacttatc tacaattaga
    25081 ttttatttga catgttttgc caattcttct tgggcttttt tattggattc ttctttttct
    25141 ttcaaccatt tttctctggc ttttgcatat tcgtctgttg tgacaatctt atcttgtact
    25201 ttgaggtatt tatatgattc aacccctttt gtaccggtta aaccataggc agcagcaaat
    25261 ggtacggttc ttctcaatga tggtgttccc ccacgcgaaa cacttggaag aactaaagaa
    25321 ctatcaatca accaagcttg aatatcagca tatttctcat aacgtttggc cggatcttgc
    25381 tctttattag cttcttccaa catttgagta tagacatcca gtccaactgc cttagccttg
    25441 tcattggcct caccaggctc tagtccaaga ttttgcagaa atcctccact attagtatta
    25501 aaaatatcga gataggttga cgggtcttga taatcaggtc cccaaccgcc atgatataaa
    25561 tcataatctt tctgagcagc tgtttgagca aagtagcctg aactgtcaaa ctcatctgat
    25621 gttaattgct gaatgtcaat cactacatta tcagaaccta aaacagattc aattgattgt
    25681 ttgatagaac taactccttg tatgcctact ttatctgtta cttccacagt cttatccaag
    25741 tggattggga attgaacacc ctttgcttcg agttctttct tagcttccgc aaacttagcc
    25801 ttggctttct caggattgta gtaagggtct tgaccatccg caaagttgat accttgccat
    25861 tccttaccat agttgaccat cttagaggct acaacttcac caaagtcttt tcccttgata
    25921 ctgacaaagt ttggaggaac cactaggtta cgcaaaatct ttgttgcacc ttctttccct
    25981 tcagactgag ccccataaga tgttctgtca aaagcaaaat tgatagcctg acggaagttt
    26041 ttattgagaa ctgcttcctg agtcgatttc ttttcaatgt cacttgtttt agaagtataa
    26101 ttgtaagact tcctatctag gttaaaatta aagaaatatg aagttgaatt ttgcatacta
    26161 tagatgatat tgtttttgta tttttcttta atcccttcat agctggagct gttaggaaaa
    26221 agacgagccg tagtataagc accagctgta aaattacgtt ccagtgattc ttggtcgcta
    26281 ccatcatagt aggtcaattt cacatcgtct acaaagacat tcttagcatc ccagtaatta
    26341 gggtttttct tatattcaat agcagatttt gagacaagtg ctttcatcaa gaaaggtcca
    26401 ttgtacaaaa tactagatgg atccgccttc ccaaaatcat ccccttttga tttcaggaaa
    26461 tctgcattaa caggaaaaag tatcgttgca agtgtttttg aattccagta aagttctggt
    26521 ttaaccaaag tatattgaac cgtttggtca tcaagtgcct tgacaccgac agttgaaaag
    26581 tcgcttgttt taccagtgat atagtcatcc aaaccagcaa cagagtcctg cactagatac
    26641 aaggcttctg attttttatc agctgcatat tgcaaacctg tcacaaaatc ctgggcagtt
    26701 acaggcgcat attcttctcc ctcagaagta aaccacttgg catccttacg aagtttgtag
    26761 gtataggtca aaccgtcctg agaaacagtc caatcctctg ctaatgatgg aataatattc
    26821 ccatattggt cattttctaa taacccgtct accaaatttg caacaatatc ggatgttgct
    26881 gcgcggtttt ctgctagata gttcaagcta gatggatcac ttgaataaac atagttgtag
    26941 gtttttgacg ccgtgctaga atttccacac gcgctcaata aaactcctgt acccaggaca
    27001 agacctgcca aggttagata tttgctctta gactttttca tttccggaac ctcctgcttt
    27061 aaatatttgt tttattatac aactcttggt ttgtttagtc aattgttttt tccaaaaaat
    27121 caaaaaaacc tcattttcta tttttgaaag ataattttag ctatttttac gctaaaaaag
    27181 gaataagttt caagttctcc taaaagattg ttcaacttat tccttttatt tataaatgct
    27241 accttacgaa agcttaaatt ttgctcgcag gcgatctgct tgggcttttc ctattacctt
    27301 atctaataaa taggtacgca gactcataac catataaagt ccacccccca tggcaccgac
    27361 aagagctaca taaaagaagc tccacaaacg tccacttggt tggaagaaaa atcctaacag
    27421 ccactggatg gttcctatta acagaaacat gactagggtc agcaaactga ttaaaatggt
    27481 tcgcttcaaa atcaccttgc gcttgacacc agttacttta caaatatccc gatacatcaa
    27541 gacgttagga atgatgagag caatggttgt tgaaatcaaa ggaccataac tgtggaagag
    27601 ggcgatggta ggtagttgca agactagctt ggcaatagaa ccatagataa aatagagaac
    27661 ggccttgcgg ttgcggaaca tggcctgaag cattggagac aagaccatgt acaagcctaa
    27721 aataatagac tgcaaaactg caaagacaaa taagcccaga gccaaactat ctggcttacc
    27781 atagaagacc gtataaagag gttctcctac cataaccact ccaaccgttg ctggtagcaa
    27841 gaacataaag agtagggtga gactgtcctg aacgagacga gaagctgctt tcaagtcccc
    27901 cttgacatag ttttccgtca aaagtggcaa accaacactc ccaatcgaaa cccctacaga
    27961 aatcaaaatc atcgtgattt tattaggatt ggctgagaaa taagaaaaca tgacaaccaa
    28021 gtcctcattg ctgtagttgg taaaccagct catactattg ataaaggtca gctgatccaa
    28081 aatctggaag agctggatgg cagaccctgt caggataaaa ggaatggctt ccttaatggt
    28141 atcaaccaag agacgcttac tgttaatctt atctcctgtt tcaaagattc ttttgagtga
    28201 accttcttgg gcaaggaaat aaatcaagac tgcaaaactg gctaccatac cgacaaaggc
    28261 agcaaaggtt gattgggtaa cggctgctag ataatctcct gaaccgagct tcataatgat
    28321 aaaggttgct aggagcatcc agataacacg aatgacctgc tcagcaattt ggctcatggc
    28381 atagggtttg aggttattca tcccttggaa aaatcctcgg ataacactca tagacgggaa
    28441 aatcaagact ccccaagcca agctttgcat gattgggatc aagtctttgc ccacgccaga
    28501 caagtctgct agccaaggag caaagacata caagactaaa gcaaaaacca ggcctagtcc
    28561 tgtcataaag cctaagaagc tccgaatcag ggcaaagcta tgctcttctt ctcgcatggt
    28621 attatacttg gcaacttgct tggccaccgc aactggaatc cccgctgttg aaaccaacaa
    28681 gaaccaagca tagatattgt aacccatggt aaagagacca tttgccttag ctgcataagc
    28741 ccccatccag atgtaccaag ggataatgta aacagccccg agtaggcgac tgataaagtt
    28801 actagccgtt agccaagcag tcccccgtaa catctgggcc tgctggtgat tgttttcgtg
    28861 cgacatagat tcctcattca attttgataa ctaggaaaaa ctccttatct tccattataa
    28921 acttttcctt gttacttgta aatttacgac tttcggttta caatagaaag tatgattaag
    28981 attgaaaccg tattagatat tttaaagaaa gatggccttt ttcgcgaaat tattgaccaa
    29041 ggtcattacc actacaacta cagcaaagtt atttttgata gcatcagcta cgacagccga
    29101 aaagtaacag aagacactct ttttttcgca aaaggcgctg cctttaaaaa agaatacctt
    29161 ctttctgcta taacacaagg attagcttgg tatgtagctg aaaaggacta cgaagtcggt
    29221 atccctgtca tcattgtgaa cgatataaag aaagccatga gtttgattgc catggagttc
    29281 tatggtaatc cacaggaaaa actcaaactc cttgccttta ctggtactaa gggtaagaca
    29341 acagcagcct atttcgccta taacatctta tctcaagggc atagacctgc tatgttgtcg
    29401 accatgaaca caactcttga tggcgagact ttctttaagt cagcgttgac aacccctgag
    29461 agtattgacc tctttgacat gatgaatcag gctgtgcaaa atgaccgtac ccacctcatc
    29521 atggaagtct ccagtcaagc ctatctggtc aaacgtgtct atggtctaac ctttgatgtg
    29581 ggagttttcc taaatatcag cccagaccat atcggcccga ttgaacaccc tagctttgaa
    29641 gactatttct accacaagcg tctcttgatg gaaaagagcc gagcagtcat cattaacagt
    29701 gacatggacc acttctcagt cttgaaagaa caggttgaag atcaagacca tgatttctat
    29761 ggtagccaat ttgataacca aatcgagaat tccaaagcct ttagcttttc agctacgggt
    29821 aaactcgctg gagattatga tattcaactc attggcaact tcaaccaaga aaatgcagtt
    29881 gctgctggac ttgcttgtct ccgtctcgga gcaagtcttg aggacatcaa aaaaggcatc
    29941 gctgcaaccc gcgttcctgg tcgtatggaa gtcctcactc agaaaaatgg agccaaggtc
    30001 ttcatcgact atgcccacaa tggggatagt ctgaaaaaac tcatcaatgt ggttgaaact
    30061 catcaaaccg gaaagattgc tctggttctg ggatcaacag gaaacaaggg agaaagtcgt
    30121 cgtaaggact ttggcctcct cctcaatcaa caccctgaga ttcaagtctt tctgactgct
    30181 gatgacccta actatgaaga cccaatggcc attgcagatg aaattagtag ctacatcaat
    30241 catcctgttg aaaagattgc ggatcgccaa gaagccatca aggcggcaat ggctatcaca
    30301 aatcacgaat tagatgcagt tattattgcg ggtaagggag ccgattgtta ccaaatcatc
    30361 cagggcaaga aagaatccta cccaggagat acagccgtcg cagaaaatta tttataagaa
    30421 tagaaaaaat caagggaaaa tgaaaccctt gattttttcc tattctttag taaaaacgtt
    30481 tttcaaacct tcaacggcac cttctacagc accttttgcg tcttctacaa cgtcttttgc
    30541 cttagcaact gttttttcaa cagctccttc aagttctgtc ttgctgtctc cagtaacttt
    30601 accaaaacct tctttgacag cgcctgttgc ttgttccaat ttgttttcaa gtgacatatg
    30661 attgtctcct ttagtttatt ccgatatgtg ttaccggtta catatagttt ataccgaata
    30721 ctaaggaaag tcaaacaatg tactcagaaa caagaaatca cgctaagtag aaagttaacc
    30781 tctccttatc aaaatcgata gccaactcat actttccatc ttcattttgc acaatatagc
    30841 ctaagacaac ctaactgtcc acaaagatat cacggcattt ctgcataagc tggtcttttt
    30901 tgagaaattt caacaaaaaa gccgtcatat acttgagggc atactcagga ttaacatctc
    30961 ctaaaatgtc atagagctcc tgctgttttt ctgtcaaagg atactgctgt ttgaccttgt
    31021 aaaaataatt ggacagggtc attttaatgc gcgcaaagtc cgtcttttca actaaaatag
    31081 ctgcattgat ttgattgcgc aattccgtct caaaactctg ctccaacaag gcttgataga
    31141 ccggactagc ttctctgaca aaaatctctt gatccagttc aagactatca agtgattcaa
    31201 gcgtaggaaa attgaggtaa tagcgcttat tttcacgtag aatcaagcct gcctttatat
    31261 actcttccat gagtttatca actgcaacat ctggaaattg agccttaatt tcccgtagaa
    31321 tcacatcctc atactgatcc agatagcgga tcaattctcc aaaaatggct gtctcgtcaa
    31381 acgagatgga ttaaaaatct gaatcatgaa gattcctttc tttacattgt aacagaggcg
    31441 atgctgccaa ctgactagga ttggtaccag cttggttcag aggaacaggc agacctagtt
    31501 ctatgtaata ctccctccaa aaatcactaa tctcctgctc cccatctcca aatttcatag
    31561 gaatagtttc aaaaataggt aggatttctg ctatatactg ggagcagtaa aaaccagctg
    31621 catctggata gaaagaagca ttgtagggtg ctccaagatg tttgcaagct ctttccttca
    31681 ccgactggat atccatttct gggtaaacat agaggtcgta taaatgattg gactcaaaga
    31741 agtctgccgg ttcttgacag acaacaccag cctgtccact agcatgataa atcatcccat
    31801 ccaaataaat ggcaacatgg ctatagttac ctgtggaagt ctggatggcc tgtcccatgt
    31861 ctgacccatc tctcacaaaa atcaaatcgc cattttctaa catacttcac tcctagaaaa
    31921 aaggagccga aactccttgc gatataaggc aaactagact ttccgatttt gagctgacac
    31981 ccaaaatctt acgcattaaa gctttcagtc aattgaggta ccacttgttt cttacgtgaa
    32041 acggcaccag caaggaaggc atgattgttt tcaagtttga agttgaaagc cgcttcgacc
    32101 ttgtccatat tggcaccaag agccaagatt tctgagtttg agttgacgat atctgtaatc
    32161 atcaagacaa agtcagagta gccgtttgat tcgttggcag cttgcattgc agcttcaatt
    32221 tctgcttggc gttccaaaac ttcagcgatg tcaactgtgt tcacttgggc aacacggaca
    32281 ttatttccgt tgagttcaaa agtcttagca tcgatatcaa tcaattcttc agcagatttg
    32341 ctagccaagt tggtaccagc tttcaacatt gccaaaccat attcttccaa gttcacacca
    32401 gccaattcag ccaattcagg agcaatgatt ttatctgttg ggtgtgttgt tggtgatttc
    32461 aaaagaaggg tatctgaaat caaacctgaa agcatcaaac ctgcaatctc tttaggcaca
    32521 gctacaccat gttctttgaa catacggtaa acgattgaag acgctgatcc aactggctcc
    32581 aaacgcatgt aaagtgggct tgcagtttca aagttagcca cacggtggtg gtctacaaca
    32641 ccgtaaactt ctacttcagc gatatctgat acagattgtt ggaattcatt gtggtcagtc
    32701 aagataactt gctctgcccc ctctgctttg gcagaagtga taacacgtgg tgcttccaca
    32761 ccaaaatagt tcaagacaaa ggctgtttct tcatttggag ttccaagggc aacagcttcc
    32821 gtatccaaac cgtaagcttc ttttgcaagg taggcaaaag ctacagatga tccgatggca
    32881 tctgagtctg gattttggtg accaaatact agaatcttgg acatgataat acctcatttt
    32941 gtttattttc tttattgtag catttttttc gctttttgac aaaggtaaga ggagtcaaag
    33001 gactccccac gattcttcaa aataactgag taaatttcta tcttgatttt cagataaaaa
    33061 ttcttccttc tgtggcctct tcttacgctt gagaagagct tcagccgaca tggcttcttc
    33121 cttactggca aaaccttgag catagataag tttgactggc aagcgtgctc gtgtatattt
    33181 ggctcccttc ccactattgt ggatagcgag gcgtcttctc atatcagtcg tatagcctat
    33241 atagtaggat ccatcacgac actccagaac gtacatataa gccttatgat ccataataaa
    33301 tctcttcgat ttcgggcgta taagagccat catcattgtg gacaatcaaa ggaggtaaga
    33361 ccttaaagcc acttgttgag ccatccttga tcgcctcaat caaaagcata ttggcttcct
    33421 tttctctttt tggataaaca aactgcaggc gcttaggggc tagattatgt cgttttaacg
    33481 tatccaaaat atccagaagt cgatcaggac gatgaaccat ggccaaacgc ccattagact
    33541 tgagaatact ctgggcacta cgacagattt cttccaaatt agtcgtgatt tcgtgtcgag
    33601 ccaagagata atgttcactc tcgttcagat tagaataagg attcaccttg aaatagggtg
    33661 gattacacaa aatcatatcc accttactcc cctgaatgtg agcaggcata tttttcaaat
    33721 catcgcagat gacctgcatt tgctcctcta atccattcaa acggacagag cgttcagcca
    33781 tatccgccaa acgctcctga atctcaacag acaatatctg tgcttgagta cgagtgctag
    33841 caaaaagccc cactgctcca ttcccagcac agaaatccac aatcaacccc ttcttaggaa
    33901 aacgtggaaa tcgtgataag agaacactat ccaccgaata gctaaaaacc tctctatttt
    33961 gaatgatttt gatatctgtc gaaaagagct ggttaatgcg ctctcctgat tttaataatt
    34021 gttcttcttc catggtccta ttatagcaaa ttcatattaa cattacaaaa aatataaaac
    34081 tctaaactac ttcttctttt ttaaatggtg cagggcttct ccagtccaga ttggtagcat
    34141 tcgtcgaaag ggagcaaagc cgtagttaaa gcggtcgctt gaaaagcgtc tccgtctagg
    34201 aaactggtac ttttcttcct ccaaagtgcg gatagaaaga ctggctttcc ctgtaaattc
    34261 atctaaatcc actacctgaa cttgaacctc ttcatcgact ttcaaggttt catgaatatt
    34321 ttcaataaat cctgtccgaa tctctgaaat gtgaatcagc cccgtatcac ccgtctctaa
    34381 ctcaacaaag gcaccgtagg gctgaatccc tgtaatacgc ccctttagct tatcaccgat
    34441 tttcatctta gtcctcgatt tcaatagttt caattacaac atcttcaact ggcttgtcca
    34501 tagctcctgt ctcaacagca gcaatggcat ccaagacagc gtaagatgct tcatcagcta
    34561 actgaccaaa aaccgtgtga cggcggtcta ggtgaggtgt cccaccttga ttggcataga
    34621 tttctgcaat cggttctggc caaccaccac gagtaatttc tttcttagaa taaggtaggt
    34681 gttggttttg cacgataaag aactggctgc cgttggtatt tggaccagca tttgccatgg
    34741 aaagagcacc acggatattg taaagctctt ctgagaattc atcctcaaaa gattcgccgt
    34801 agattgactc gccacccata ccagttccag ttgggtctcc accttggatc ataaagtcct
    34861 tgataatacg gtggaaaatg acaccatcat agtagccatc ttttgaaaga gatacaaagt
    34921 tagccactgt tttaggagca tgttcaggga aaagcttgat acgtaagtct ccgtgattgg
    34981 tcttaatagt cgcaagagga ccttctactg tttcaatgtc tacttgtgga aaatgcaatt
    35041 ctttttctac cataccaaat acttctaagg cagcaaaaat gccatcttct tctaatgttt
    35101 ttgtaatata atctgctttt tctttgattt tatcatgaga aattcccatg gcaacgctga
    35161 ttccagcata atcaaagagt tccaagtcgt tgagaccatc tccaaaaacc atgaccttct
    35221 ctggtttcaa gccaaggtgt tccacaacct tttccacccc cgtcgctttg gagcctgaaa
    35281 tcggcacaat atcagacgaa tgttgatgcc aacgaaccat gcgaagtttg tctgagagac
    35341 tgtcaggcaa gtgcaagtca tctcccttat cttcaaaagt ccacatctga tagatatctt
    35401 ctttttcatg gaaatcggga tctacatcta agtcgggata aattggattg atagcttcac
    35461 tcatcatatc ggtgcgagtc gacaacttgg catcatgact cccaaccaag ccatactcaa
    35521 ttccttcttg cttagcccaa gagatatact cctcaacatc tgacttttca atctgatgct
    35581 gataaatgac ctgacctttt ttatcttcga tataagcccc attcaaagtt acaaaaaagt
    35641 caggcttgag atcacgaatc tctggaacaa caccaaaaat gccacgtcca gaggcgattc
    35701 ctgttaaaat tcctttttca cgcaactgtt taaaaacagt gggaattgta gttggaataa
    35761 accctgtctt tgaattccgc aatgtatcat caatatcaaa aaagacaatc ttgatcttct
    35821 ttgccttgta tcttaatttc gcgtccatct cactacctct ttcaatctaa ctctttccat
    35881 tatatcataa agtaggcaaa tcccctattt tcaaaaagtt tatcattttt attttaattt
    35941 cttggatgag aaaagagaca tatttatgaa aaagctccat cgtgctttta atgtgttctc
    36001 ttgttttcaa actcgtaaaa agggagccac tgatcctaac tcgctctctc atttcaaagc
    36061 ttgtgaaaaa agacccgttg gggtcttaat tcgctttctt gttttcaagc tcatgaaaaa
    36121 gagacccaac tgggtctttt ctttaatctt cgtttacgaa aggcatcaaa gccattacgc
    36181 gagcgcgttt gatagctgtt gttactttac gttggttttt agctgaagtt cctgttacac
    36241 gacgaggaag gattttccca cgttctgaaa cgaaacggct aagaagctca gtatctttgt
    36301 aatcaacata ttcaattttg tttgctgcga tgtaatcaac ttttttacgg cgtttgaatc
    36361 cgccacgacg ttgttgagcc atgttttttc tcctttataa gtttagttgt ccattagaat
    36421 ggtaaatcat catctgaaat atccaatggg tttgttgctc caaatggatt ttcattacgt
    36481 gaaaagtctg gtactgaatt tgtaggtgct gaatagtttg cagttggtgc agagtaagct
    36541 ccacctgtgt gaccctcacg cacactacgg ctttccaaca tttggaaatt ctcagccacg
    36601 acctctgtca cgtagacacg ttgtccttgc tggttatcgt aactacgagt ctggatacga
    36661 cctgtcaccc cgataagtga gcctttttta gcccagttag caagattttc agcctgttgg
    36721 cgccacataa cgacattgat aaaatcagcc tcacgttcac cattttgact cttaaatgta
    36781 cggtttactg caagagtaaa agtcgcaact gctacatttg atggggtata acgcaactca
    36841 gcgtcacgtg tcatacgccc tacaagtaca acattgttaa tcatagttta ccttcttacg
    36901 cgtcaatttt gacgatcatg tgacgaagaa tgtcagcgtt gatttttgaa agacggtcaa
    36961 actctttaag agctgcatcg tcatttgctt caacgttaac gatgtggtaa agtccttcac
    37021 ggaaatcttg gatttcgtat gcaagacgac gtttttccca agtttttgat tcaacaacag
    37081 ttgcaccgtt gtcagtcaaa atagagtcaa aacgtgctac caaagcgttt ttagcttctt
    37141 cttcaatgtt tggacgaatg atataaagaa tttcgtattt agccattgat atgttcctcc
    37201 ttttggtcta atgaccccaa gactttgcaa ggggtaagtg aggttcgctc acaataaact
    37261 attatactag aaaaaatttt tttacgcaag taaaaacact agaattcgaa aaaacgccac
    37321 atgggcgttt tcctgttctt atggtttgat acggtgcaac atacgtggga atggaatagc
    37381 ttcacggata tgttttgttc ctgctgcgaa ggttaccata cgttcgatac cgataccaaa
    37441 tcctccgtgt ggaactgtac cgtatttacg aaggtcaagg tagaattcat attctgtacg
    37501 atccatgcca agttcatcca tcttagcgac aagggcatcg taatcttcct cacgcataga
    37561 cccaccgata atttctccat agccttctgg agcaagcaag tctgcacaaa gcacgcgctc
    37621 tggatttcca ggaactggtt tcatgtagaa ggccttgatg gctgctggat agttcatgac
    37681 aaatgttggc acaccaaagt ggtttgaaat ccaagtttcg tgtggtgacc caaagtcatc
    37741 accatgctca agatgctcgt agtcagcatc ttcatcattt tcatgctctt gcaagaggtc
    37801 aatggcttga tcgtaagtga tacgtttgaa tggctctgca atgtagcgtt tcaagagttc
    37861 tgtatcacgt tccaaggttt ccaaggcttg aggcgcgcgg tcaagaacac cttgtagaag
    37921 agctttcaca taagcttctt gcaagtcaag cgactcatca tgtgtcaagt atgagtactc
    37981 agcatccatc atccagaact cagtcaagtg acggcgtgtt tttgattttt cagcacggaa
    38041 aactggacca aagtcaaaga cacgaccaag agccatagcc cctgcttcta ggtaaagctg
    38101 acctgattgg ctcaagtagg ctggcgttcc gaagtagtca gtttcaaaga gttctgtaga
    38161 atcttctgcc gcatttcctg aaagaattgg gctgtcaaac ttcataaaac cgttcttgtc
    38221 aaagaactca taagttgcat agataatagc gttacggatt tgcaacacag ctacttgctt
    38281 acgagagcgt agccacaagt gacggttatc catcaaaaag tctgttccgt gttcttttgg
    38341 tgtgattggg tagtcttgag attcaccgat cacttcgatg tctgtgatgt ccaactcata
    38401 gccaaattta gaacgttcgt cctctttgac aatacctgtc acataaacag acgtttcttg
    38461 gctcaagcgt ttgataacat caaacttctc aagtcccact tcttcaccaa atttttcgac
    38521 aaagtttggt ttaaaagcca caccttgaaa gaaggctgtt ccatcacgca attgtaagaa
    38581 agcgattttt ccttttcctg atttgttggc aacccaagcg ccaatcgtca cttcctgacc
    38641 aacatagtct tttacgtcaa taatcgttac acgttttgtc attatttttc cttttctttt
    38701 ttattcttta tggcaaacca cctctatatt gttcccatcc aggtcaatca taaaagcagc
    38761 atagtaaatc ggatgctcac ttcgataacc aggagcccca ttgtctcgcc cacctgcctc
    38821 taagccagcc tcataacaag cctgaacttc ttccttattt tctgctaaaa aagcaaaatg
    38881 aacaggatct tgtgttccct gagtcagcca aaaatcacca ccaggatgag ggctgttcgg
    38941 ggatagaaaa ctaattagag aactagtctt aaaagccaat ttatagtcca aaggagcgag
    39001 aaaactccta taaaatcctt atgaaatttg taaatccttt accttaatct caaaatgatc
    39061 aatcattctc actacccata aatgctttca agcgttcgac tgcttcttta agcgtgtcta
    39121 ggtctgtcgc atagctgagg cggacatttt ctggtgctcc aaatccagct cctgttacca
    39181 aggccacttc ggcttcttct aagataacag ttgtaaagtc tgtcacatcc gtgtagcctt
    39241 tcatctccat ggcctttttg acatttggga agagatagaa ggccccttgc ggtttgacca
    39301 cttcaaatcc tggtacctct gcaaggaggg gatagatggt attaagacgt tcctcaaagg
    39361 cctgacgcat gctttctaca gtatcttgct cacctgatag agcctcaact gctgcatatt
    39421 gggctactgc tgacggattc gaagttgttt gacctgcaat cttggacatg gcagcgataa
    39481 tgtctgcttc tccaacggca taaccaatcc gccaaccagt catggcataa gttttagaca
    39541 caccattgat gaccactgtt tgcttgcgaa tcgcttccga taggctagaa atcggtgtga
    39601 actcatgacc attataaacc aagcggccat agatatcgtc tgctaggatg agaatatcat
    39661 tttctacagc ccagtttcca attgccaaga gttcctcacg ggtgtaaatc atacctgtgg
    39721 gattagatgg cgaattcagc accaaaacct tggtcttgtc agtgcgagct gcttctaact
    39781 gctctacggt caccttaaag tgattgtctt ccttagcaga aacaaagacg ggaacgcctt
    39841 ctgccatctt gacctgatct ccatagctaa cccagtatgg ggttgggatg atgacttcat
    39901 cacctggatt gaccacagcc ataaagaagg tatagagaga atatttggct cccgcagcga
    39961 ctgtcacttg atttgacgct acagaatagc cgtaaaagcg ctcaaagtag ctattgaccg
    40021 ccgccttaag ctctggcaga cctgaggtta ctgtataaaa agaagcacgc ccatctcgaa
    40081 tcgatgcaat ggcggcatct tggatatttt tgggagtagt gaaatctggc tcacccaagg
    40141 ttagagacaa aatatctcta ccctcagcct tcagtgcttt ggcacgggct ccagcagcca
    40201 aagtcacact ttcttccatt tctaaaacac ggttggatag tttcataggc cctccttgtt
    40261 gaccaatgct cctgtttcaa aatctactag ataaaaatca gatcctgact taacttccca
    40321 gattggctta tcttgataac ggccaaaggt tatcttgtca atctcgccag ctcccttttc
    40381 cttagaaacc gtttctgctt tttcttgtga aacaccctga tttagctgat aaacgtaaat
    40441 cttatggtca tctttaccaa tcaggacagc aagcgcttct tgctgtttgt tacgaccaag
    40501 aacgctgtaa taagattcca agccattgta taaatcaacc tgatcagcct gctctaatcc
    40561 tgcatactgc tgagctaatt tttctccttc acttttagct gtttgatagg gtttcatgct
    40621 aagagaaacc atatacagaa aggaaccact gataaccaca aacaaaatcg tcatccctag
    40681 accatactgc cacagtagat tattttttgc tttgttttgt ctttttttca ctcgtctatt
    40741 ttaccatcta ttaagcttta ttacaagtga atataagaat actcttcgaa aatctcttca
    40801 aaccacgtca gctttatctg caacctcaaa gctgtgcttt gagcaaccaa ttctatttct
    40861 cccttcaaac aaaaccgatt ttgaaagtga aacagttctt actttttcag tcacaaatga
    40921 ttagagtttc cgaaatttta caattttcaa ataaactctg agcaaatttc ttgcaagttc
    40981 ttttgttttg ttgtaatata ttttataaca acgagagagt tctcgaaatt ttaagaaaaa
    41041 ggagacacat catgtctaaa aaagtattat ttatcgtcgg atcactacgt caaggttctt
    41101 tcaaccacca aatggcgctc gaagctgaga aagcacttgc tggtaaagcg gaagttagct
    41161 accttgatta ttcagccctt cctctcttca gccaagattt ggaagttcca acacatccag
    41221 ctgtagctgc tgctcgtgaa gcagttctcg ttgcggatgc tatctggatt ttctctccag
    41281 tctacaactt ctctatccct ggtacagtga aaaacttgct tgactggcta tctcgtgccc
    41341 ttgacttgtc tgatacacgt ggcgtttctg cccttcaaga caagtttgtc acagtatcat
    41401 ctgtagccaa tgcagggcac gatcaacttt tcgctatcta caaagacctc ttgccattta
    41461 tccgtacaca aggcgttggt gatttcactg ctgcacgtgt taatgactct gcctgggcag
    41521 acggaaaatt ggttcttgaa gaaacagtcc taaactcact tgaaaaacaa gctcaagact
    41581 tggtcgaagc tatcaagtaa ctaacactca ataaaaatca aaaagcaaac taggaagcta
    41641 gccgcaagct actcaaagca ctgctttgag gttgtagata gaactgacga agtcagtaac
    41701 atatatacgg taaggcgaca ctgacgtggc ttgaagagat tttcaaagag tataacataa
    41761 taaaagcgaa caagactact tttctgacac tcagaagact agcttgttcg cttttttctc
    41821 atttataaac taaaatagct gatgatacat attgccaaat acaaaatatc tgatttctat
    41881 acttccttta caaaaaccaa tccctgtggt tgtgacaaat cttctcggta aacaaatcca
    41941 gcaaagttca agcgacgtgc ttcccccaca gtttgtactt gattttctat taaagctgtt
    42001 agaaaggccc cgcgcgcttt cttggagata gttgagtgaa tcttcagctg accgcctcta
    42061 tcctccatga atttgaaggt caccatcttt gctctgattt ccttagaaaa tacagtctca
    42121 aactctgatg acaagagaga gaaaatcact tcttccttct tcagagtttc atcataggct
    42181 gccttccaat ggctcttcaa agtcttacca gcgactttta atttcatcaa aaaatccaaa
    42241 cggtgaggag ccatgggtga caagactgga acaacaccgt acaaagccga ggtaatgaaa
    42301 acatgatttt caagataatc ttgttccgcc tcggtcagct tatctctctt aatgttgcgg
    42361 tacataagcc catcaaaaag tttcaaggct ggatagtgtt gagcagtttg ccttttcaaa
    42421 gcttggatat tttgaaattc ttccgccgct ttctcagctg ataccttgta gaaactctcc
    42481 aattgactgg cagaatagag agccaaggca tcaagcacgg cctgactttc tggttttaaa
    42541 ggaattgcct cgatacttgg gaagtctgtg ttcatttctt ttgctgttgg gattaaaatt
    42601 ttcatattga tagtgtagca tattttttag ccacaaccaa gaaattcatt taaaaaacct
    42661 cggtttgacc gaggtttttc tatttatttg ggccatccta accagacagc cacgagaaca
    42721 agggctgtgc cagctaaact tgttaagata gataagaatt tatctttttt ctccttgaac
    42781 tgagaaaaac ctatcttcaa agcgagcagt ccgagtagca ttgaagcaac catcaaataa
    42841 aaacccattt ctttgtcctc cattaggctt aatttacctt attataacat atactttctg
    42901 aaaaaaacct atttttaccg tagcttaaag gtcttgagat aattgtcttt tcctacttga
    42961 ccttcgaagg ttttaccatt ttcaaggtaa ggaaggtcat cggatactga agccttgacc
    43021 ttgtatatct tgccatcaac tttaaagaag tagacagtgt ctcccttgat aacagctgat
    43081 ttgaggtctg ctactactcc attgatgctt tctgtcgttg cattgtcaat ttcaaggtcg
    43141 tttttattgg catacttgct gagcatctct tccactgtag tagcaacgat aacattttgg
    43201 tactcgactg cgtctaccag ggcgtactct ttgaccaagc cagcattgtc cttcaagccc
    43261 atgatgtaga gaggcttgtc attgaggttg atgaggattg ggaaggttgc tttgtaggat
    43321 ttctcctgaa cagcaccttc tgctgattca cgggctgatt cttctgtcgc agaagccaag
    43381 ctatacttag tgatttctcc tgttcgcata ttttcaagga tgaaaccaag attactctca
    43441 tccgcattag ccgacgtcac acctgtgtag agatagatgt cattaccgat agacaagtaa
    43501 ttatagccat tggtagtctg ggtcacgttt ttcttggaaa tcatggcatt caagaaaccg
    43561 tccttgtact tgccgttgta gttgatttgc tcaatggttt cctctgctgg atagatcctg
    43621 tccacccatt ctggaacatc tgataagctg tattccttgg tttctccatt tgtagcatcc
    43681 aagataatga ctgaagcagg acgaggaaca gcaagtccaa attgcttttg gtaaaccgtt
    43741 gctacataga aaggattgcc ctcatcgtcc acctcaaaag atggagtttt aaagattttg
    43801 gtcgggtact tcaagcgcag gtgacgtttg acatcacggt taaaatactc cgagtctgaa
    43861 tacttgattg gtgtcttcaa gtccaccaaa tccgcatttc cagttaccat gtccacctta
    43921 atatactcac cgattccctt ggcttgattg ttaaaccatt tgatagggtc tgcatattct
    43981 agtggtgtga cccgataagg tttcccatca attgtcaatt gggtataggt atctgccgct
    44041 acgtattgcg acaccttatc ggttagggaa cccaagtagc ggtctccaat tttttcagca
    44101 gtacttctat ctaggatagg aaccttactg gtgtcactct taggaaattc agtaaagtct
    44161 ttttccgtaa ccgtgactac attggcataa tttttagcct gaaacatgct ggaagttacc
    44221 aaggaaacca aagctgccaa gagaagaatt cctccaatcg aagctaacag aattttccct
    44281 aaccgattga ttttgaaacc ctcaagattt aaggcagctt ccgccttacc gtggcgcaca
    44341 tgaaccgttt tgacaaggtt tatccccttg ccaaagccaa ataatattgc cacaactaac
    44401 aaatgcccac agaggaagaa gagaaattcc cagctggtca ggttaagggg cggtaaaaag
    44461 atataccagg tcgttgcgat aaaaataagt tcaaagacta ttcgtttcat ttgctttcct
    44521 cctaaatgat tcgtccttcc aagtgatcca gctcatgctg gcaaatctga gctgggaagc
    44581 ctgtcaaggt aatggtctgt tcctgccact tgctgtcacg ataggcaagc cttatggttt
    44641 cataacgctt agttgatctc acacctacca aggacaaaca gccttcttct gcctcatagg
    44701 atccttcaaa ggacagaagc actgggttaa acatgaccac aggaaccaag ccaagattaa
    44761 agataatcac gcgcttctgc accccaatca tattggcagc tagaccaaca caggtatcac
    44821 gatttgctaa gagtgtatcc tgcaaatctc tggcaagata aaggtcctcc tgacttgccg
    44881 gctgagacac ttgagataaa aataagatat ccttcacaat tttcttttcc acttcctcac
    44941 actcctcttg ctttttacta tattatagca attatagcac aaaagccgat aactgcaaac
    45001 cctttccctc aactgtagca aaaagccatc cgaagatgac ttttttgcta tttaatttct
    45061 gtataagtta cttccaagcc acgcttaaca gctggacgat tggcaatttt ttctgcccat
    45121 tttactagat tttgataact tgaggcatcc aagaattttg cagaaccttg gtaaagattt
    45181 ccttgaacta actgtccata ccaagaccag atagcaatat ctgcaatcgt atagtcattg
    45241 cctgcaatat aaggtttctg agccaattcc ttatccaata aatccaactg gcgtttcact
    45301 tccatcgtaa aacggttaat aggatattcc aatttttcag gagcataatt gaagaaatgt
    45361 ccaaatcccc cacctagaaa aggtgctgca cctgcttgcc agaatagcca attcaaaact
    45421 tctacctttt ccacaggatt acttggtaaa aaggctccaa atttctcagc aaggtaaaga
    45481 agaatatgag cagactcaaa gactcttacg ttttcagtac ctgactggtc caataaggct
    45541 ggaatcttgg aatttggatt gagcttcaca aagtctgatc cgaattgatc cccatccatg
    45601 atagcaatct tatacaagtc gtaagccgct tccttaaaac cagcttctag taattcttcc
    45661 aataagatag taaccttcac accatttggt gttcccagtg aataaagctg aaaagcttgt
    45721 tctccttttg gcaagttttg ttcgaaacgg gcacctgctg ttggtctgtt tagccccgta
    45781 aaagctcctt gattactagc ttcatcctgc catacggtcg gtaattgata tgctgacatc
    45841 cgaaacctcc cttaaatcgc attcttgtca aaaccgagtt tgcgttgaat aaacttaacg
    45901 atttcgacga tgataatcat tgagaagctt ccagccataa caattcccca ttgtgacaag
    45961 tctagtttgg ttacgtggaa gattccttca agcggttcta caacgattgt tgccatgaga
    46021 aggataaagg ataccaagat ggaccagtta aaggtcttag acttgaatgg gccaactgtc
    46081 aagatggatt ggtagacaga cttgacattg taggcatgga agagctgaat caaaccaagg
    46141 gttgcaaagg ccatcgttag ggcatctgca tgaatagcat gattgtcacc cacatgaact
    46201 gggtaagcaa tcgcaaggcc ataaacactc ataacaagag ctgcttggag tacaccttga
    46261 taaatgatag aactcaaaac accacctgag aagaagcttg ccttgcgtcc acgtggttta
    46321 tgattcatga caccaggttc cgcaggttca acaccaagag cgatagctgg gaaggtatcc
    46381 gttaccaagt tgatccacaa aagatgaacc ggctgtaaga catcccaacc aaacaaggtt
    46441 gataggaaga tggttaatac ttcagcagta ttagcagaaa gtaggtactg aatagtcttt
    46501 tgaatgtttg agaagacctt acgtccttct tccactgcga cgataatagt cgcaaagtta
    46561 tcatctgcaa gaatcatatc agaagccccc ttagaaacct ctgtaccagt gattcccata
    46621 ccgataccga tatcggctgt tttcagagct ggcgcgtcat tgacaccgtc acctgtcatg
    46681 gcaacgactt taccttgttt ttgccaagcc ttgacgatac gaaccttgtg ttctggagac
    46741 acacgggcat aaacagagta ttgaccaacg actttttcaa attcttcatc tgacagttca
    46801 ttgagttcag caccagttaa aacgtgacct tctgtatcgt ttgcgtcaat gattcccaaa
    46861 cgtttggcaa tggcttccgc tgtgtcttgg tggtcacctg taatcataat tggacggatt
    46921 cccgcttcct tagccacacg aacagcctca gcggcttcag gacgttcagg gtcaatcatc
    46981 ccaatcaaac cagtaaaaat taaatcattt tcaagctctt cagaagtgag attttctgga
    47041 atactatcga taatcttata agcacctgca aggacacgca aggcttgatg agccatttca
    47101 gaattgtttg tacgaatgag atttgtaacc ttctcatcaa tcggagcaat atccccagcc
    47161 ttatcacgaa gaagacaacg ttttaagagt tggtctggcg cacccttgac tgctacaagg
    47221 aaacgaccat ctggcaatgg gtgaactgtt gacatgagct tacggtcaga gtcaaatggc
    47281 aattcagcta cacgaggata tttctctaag aaacctttga catcatagcc cttgtccaag
    47341 gcatattgga taaaggctgt ttcggttggg tcaccaatca agttaccttc cacatcgatt
    47401 ttcgtatcat tggccaagac aactgaacga agtagtggca tttcaagacc tagttcaata
    47461 tcatcagctg agtcatgtag aaccgcatcg tagaagactt tttcgactgt catcttgttc
    47521 atagtcagcg taccagtctt atcagaagcg atgatttcag ttgaaccaag tgtttcaact
    47581 gctggcaact tacgaacgat ggaatgtcgt ttggccaaaa cttgagtacc aagagaaaga
    47641 acgatggtaa cgatagcagg aagtccttct ggaatggctg caacggcaag ggcaacagaa
    47701 gtcaacaact caccaagtgg atttttccct tgaatgaaga cacccactac aaaagtaaca
    47761 agggcaatga ccaagatagc ataggtcaag accttagaaa ggttgttcaa attttgtttg
    47821 agtggtgtat cagtctcatc cgcatcttga agcataccag caatatgacc aacttcagtg
    47881 tacatacctg tattgacaac aacacccatc ccacgaccat aggttacgtt tgagttttgg
    47941 aaggccatgt tgacacggtc accaatacca gcatctgtcg caagctcgac tgacaagtct
    48001 ttttcgactg gtacagattc acctgtcaag gctgcttctt caattttaag agagttggct
    48061 tctatcaaac gtaggtccgc tggtaccacg tcacctgctt caagggcaac gatatcgcct
    48121 ggtaccaatt ctttagagtc aatctctgcc atgtgtccat cacgaagaac gcgggcaact
    48181 ggactagaca tggatttgag ggcttcaata gcttcttcag cttttccttc ttggtaaaca
    48241 ccaaaggcag cgttgatgat aaccacagct aggatgataa tggcatctgc gatatcttcc
    48301 ccaccagaag tcacgactga caagattgct gccgcaacta ggatgataat catcaaatcc
    48361 ttaaattgct cgatgaattt gaccaagatt gatcgtttct cgccttcttc gagttcattg
    48421 tgcccaaatt cggcaaggcg cttttccgcc tcacttgatg acaaaccttg ctcggtcgca
    48481 tccacagcct gcaagacctc ttcagggctc tgagtataaa acgcttggcg tttttgttct
    48541 tttgacatgt gtctcctcct tgacattgtg tgcaaaacag actctctttc tgtcatagct
    48601 tttcacgaca aacaaaaaga aacctgttaa tcataacaag tctcgctgtt taagataggg
    48661 ccggaaagca tacttttcag cataaaattc ggaatgacga cactatcaca ggtttctgcc
    48721 agctactccc ttgagtagta ccattatacc aaattttggg gagttttcaa agagtaaaaa
    48781 ctgccttatt tgaatttttc cttgaaaacc agtataatgg tagaatgcta tgtgactaga
    48841 aaggaagttg aatgaagcaa tctatctcaa atctcaagtt agctgagcgt ggagccatta
    48901 tcagtatttc gacctatttg atcttgtctg cagccaaatt agcagctggt catctccttc
    48961 attcatccag tttggtggcc gatggtttta ataacgtatc ggacatcatt ggaaatgtgg
    49021 ccctcttaat cgggattcgg atggcgcgcc agcctgcaga ccgtgaccac cgttttggtc
    49081 attggaagat tgaagatttg gcaagcttga tcacttctat catcatgttc tatgtcggtt
    49141 tcgatgttct aagagatacc attcaaaaga ttctcagtcg ggaagaaacg gtcattgatc
    49201 ctcttggtgc aactctagga atcatttctg cagcgattat gtttgtggtc tatctctaca
    49261 atactcgcct cagtaagaaa tccaactcca atgcgctgaa ggcagctgct aaggacaatc
    49321 tttctgacgc tgttacctca cttggaaccg ccattgccat cctagctagt agtttcaatt
    49381 atccgattgt ggataaactg gttgctatca tcatcacttt ctttatcttg aagactgcct
    49441 atgatatctt catcgagtct tcctttagtc tttcagatgg ctttgacgac cgcctgctcg
    49501 aggactacca aaaggctatc atggaaattc ccaaaatcag caaggtcaaa tcgcaaagag
    49561 gtcgcaccta cggtagcaac atctacctgg atattacact agagatgaat cctgacttgt
    49621 ctgtttttga aagccatgaa atcgcggatc aggtcgagtc tatgctggag gagcgttttg
    49681 gcgtctttga taccgatgtc catatcgaac cagcacctat ccctgaggat gaaattttag
    49741 acaatgtcta taaaaaattg cttatgcgtg aacaattgat tgaccaagga aaccaactag
    49801 aagaactctt gactgatgat tttgtctata ttcgccaaga tggagagcag atggataaag
    49861 aggcttataa gaccaaaaaa gagttaaatt ctgctatcaa ggacattcaa attacttcca
    49921 tcagtcaaaa aaccaaactc atctgctatg agttagatgg tatcatccat accagtatct
    49981 ggcgtcgcca cgaaacctgg caaaatatct ttcatcaaga aaccaaaaaa gaatagagaa
    50041 atcctttcat gagacgggat ttttctattc ttttatactc aataaaaatc aaagtgcaaa
    50101 ttaggaagcc ggtcacaggc tgtacttgag tcggcaatgt gaagccgaca tagtttgcac
    50161 tttgattttc gaatagtctt aactatcaaa ttcactgaga tactcatagc gttcgtattt
    50221 ttcaaggagt gcttcatttt tctcatccaa ttctttttgg agagtagcca gcttaccaaa
    50281 gtcagagccg ttagcctgca tttcctcttc aatagcagcg atacgttttt ccaaggtttc
    50341 aatatcacct tcaatacttg cccactcctg cttttcttgg taggtcatgc gtttcttgtc
    50401 ttctcgaacc ttgaccactt tttccttttc ggccttttgc acttgattgg ccatatctgt
    50461 ttcaaaagct ttttcatcaa gatagtcggt gtaatgacca aagaaaggac gaatcttgcc
    50521 atcctcaaaa gcgagaatct tggtcgctac cttatccaag aaatagcggt cgtgactgac
    50581 tgttaaaacg ggacctgcaa aaccttgcaa gaaattctct aagactgtca aagttgcaat
    50641 atctaggtca ttggttggct cgtctaaaag aagaacattt ggtttttcca aaagcagttt
    50701 gaggagataa agacgttttt tctcaccccc tgacaatttc tcaatcaaag tcccatgcgt
    50761 cgaacgtggg aagaggaatt gctccagcaa ctcagcgatg gaagtcgtag aaccaccact
    50821 ggtcttgacc tcctctgcca cttcctgcag gtaattgatc acacgcttgc tttcatccaa
    50881 accctcaatt tgttgagaga aataggcgat gcgaacagtt tccccaatca caacttgtcc
    50941 tgctgtcggc tcaagacttc ctgcaatcag gttaagtagg gttgattttc caacaccatt
    51001 gtccccaaca attccaatac ggtctttagc ctgaactaag agattaaaat tttgcaaaat
    51061 gggcttattt tcataggcaa aggaaacatc ctgaaactcg atgactttct tcccaatccg
    51121 actggtttca aagttcatag tcaagtctgt ctcagcacta ctgcctgaaa cttccttttt
    51181 cagatcatgg aaacgattga tacgagcttg ttgcttggtc gcacgcgcct gcggttgtct
    51241 gcgcatccag gccaattctt gtttgtagag ttgttctttt ttgtgaagaa gagccgcgtc
    51301 gcgctcatcc tgttccgcct ttaggcgaac atagtcctgg taatttccct ggtactcggt
    51361 caagcctgca cgatccaact cgaaaatccg tgttgacaaa gcgtctaaga aataacgatc
    51421 gtgagtgata aaaaggacgg tcttcttaga atttttcaaa aagagggtca gccactcaat
    51481 aatcgcaata tccagatggt tggtcggctc atccaaaagc aagaggtcgt ggttgccaag
    51541 taagacttgt gccaactgta cccgtcttct cagaccacct gacaattccc caacaggagt
    51601 agataagtct tgaatgccca atttgctaag aacggtcttg acctgacttt cgatttccca
    51661 agcttggaga gagtccatct ctgccatgac acgttccaaa cgcgcctgct tgtcctcact
    51721 atagtcgagc ataatcaatt catactcacg aatgagctgg atttccttga gttcactaga
    51781 tagaaccgta tccaaaactg tctttctatc atcaaaatca ggatcctgag tcaagtaacc
    51841 aatctggtaa tcatttttag ctgaaaaagg actgacatcc ccatcaaatc cagaaacacc
    51901 agaaaggacg tccaaaaggg tggtcttgcc agtcccattg acaccgatta aaccaattct
    51961 gtctaagtca tggataataa aggaaatatc cctaaaaacg gtcttgtcac caacggattt
    52021 acttagtttt tcaacgataa aatcactcat tttttctccc tcaggtaagc atggatggct
    52081 tcacgattat tctccaattc tccatcgaca atggcaaact caatctctgt taaaatctct
    52141 cccaagtctg ggcctggctg atagccatat tccttgatca aaataccgcc attaatctga
    52201 atctctttct tgtcatggat agtcaagctt tggtattttt ctgtgatggc ttgtgggttg
    52261 acttcttttc cttgagcttg acgaagattt tcagcctgta aaagcaaatc tatgtcaaag
    52321 cgataacaat ctcgcttgct caattctcca ttttcacgca gagccaaaat aatcagcaaa
    52381 tcctgaactt gcttggcaaa ctggcgtgag gtcttccaag atttcaaaaa tgactgcgca
    52441 ttttcaatct ccaaagccca tagtaaagcc gcccaggctt gttcagagga ttcaaaagta
    52501 aaatcagtct ccaaatcaaa cagtctgttg agcttgtcct ggctagatgc catatcaggg
    52561 agatagtcat aagcttgact ctcaatcatg gaagccaagc cccttctcca aaatggagcc
    52621 agcaagagtt tatcaaactc gacgaaggta cgctctacag aaattttctc caaaagcggc
    52681 gtcaaggtct tcatagcttt aaatgtttct ggctcaagtg caaaaccaag actagcctga
    52741 aaacggaaac cacgcataat ccgtaaagca tcttcgttga aacgctcact agccactcca
    52801 actgctcgca agacttgctt ttccaaatct tctaaaccat ggaacaagtc aacgatttct
    52861 cctgtctcat ccaaggcaaa ggcgttgact gtgaaatcac ggcgtttgag gtcttcttct
    52921 agcgatcgta caaaggaaac cgcactgggt ctgcgatagt ccacatagac atcctctgtc
    52981 cgaaaggttg ttacctcata ctcctcatcc ccatctaaga ccaagacggt tccatgctcg
    53041 attccgatat cggctgttcg cggaaaaatc tgcttggtct cttctggata agaagacgtc
    53101 gcaatatcca catcgtggat agggctatgg agaagggcat ctcgaacaga gcccccaaca
    53161 aaataagcct caaagcctgc ttctttaatt ttttctaata ctggtaaagc cttctgaaat
    53221 tcagaaggca tttgcgttaa tctcataata agtgttctaa tccatagaca agctcatgac
    53281 gcttgacaac ttctttaatt cccaaattga ctcctgtcat gaaggagatg cgatcatagg
    53341 agtcatgacg gagggtcaac ccttctccct gattgccaaa gatgacttcc tgatgagcta
    53401 ccaagcctgg caaacgaact gagtggatgc gcataccatc aaagtcagca ccacgagcac
    53461 cagcaatcag ctcttcctca tctgctgcac cttgctgaat tgactctcga acctctgcca
    53521 tcaactcagc tgttttaatg gctgttccac tcggagcatc ctttttcttg tcatgatgga
    53581 gctcaataat ctccacattt gggaaatatt tggcagcctg cgtcgcaaat tgcatgagta
    53641 agacagcacc caaggcaaag ttaggggcaa tcaggccacc caagtcttgg gcacgagaaa
    53701 attcttttag ctctgcaatt tcttcactcg tgaaaccagt cgttccaact actggagcaa
    53761 agccattttc aagagcaaaa cgtgtatttt cgtaggcaac agctggagta gtaaaatcta
    53821 cccagacatc cgcttcaaaa ccagctaaat cagccttatc cttgaaaaca ggaataccct
    53881 gccattctga ctcagactca aaaggatcca aaactgccac caagtccaag tctggatcag
    53941 tcaataccat ctgacaagca gcctggccca tctttccctt aaaaccggca ataattactc
    54001 gaatactcat ctctactcct gtctaagata caaagtccgt aagaacacaa agtgaaaata
    54061 ggaattccaa tcaagaagtg tctacttctt ggaagaacta tctttttcac acagggttcc
    54121 aggcgtgttc aattatcaag atacaaagga ccttagctgc ctctgaaaaa tagggaatgg
    54181 cactgacttt ccacgaaagg caagacaggc atcttttttc aagaggcagg tagtccgtgt
    54241 tcaatttcta agatacaagg catcttaact agcctagaag cgccaactaa atcactagaa
    54301 tataacccag agcaatactt cctgctccta ggtgcgttcc aatgacacta ccaaatgtag
    54361 caagtgaaac atccgaaccc aagccaaaat caagcaagtg ctgacgcaat tcttcagcct
    54421 tttcaggagc attcccatga atgacaatga cccggtattg acctgaagcc gttgtttcct
    54481 tgataatttc aattaagcgc ttggtggcct tcttttcagt acgaactttt tcgtaaactt
    54541 caatcacacc ttgatcgtta aaataaagga ttggcttaat gctaagcaaa ttgcccaaaa
    54601 tggcagcccc atttgaaagg cgtccacctt ttaccaaatg atccaagtca tctaccatga
    54661 taaaggctga cgtacggctg atttgaatgg ctagcttatc ctgaatgctg gcaaaatcat
    54721 cgccctgatc acgccaatta aagacgcttt caaccatgat gcctagggga gcacttgtaa
    54781 tcaaagtgtc tgggaaagca atggttaagc cctcatagtc atcgaccata tactggatat
    54841 tttggtaaaa acctgaaatt ccagaagata ggaaaagccc caaggcatgt gtatagcctt
    54901 gttctttgag cgaagttaag atctcatcta acttggcaat acttggttga ctggtcttag
    54961 gcaattcaga agcctgagcc attttttggt aaaattcctc agcagacaga ttgatgcctt
    55021 cgacatattc ctcaccatca atattgacag gaatatccaa gacaaacaag tcttctcttt
    55081 gcaagatctc tgcactgaga taagcagagg aatctgtgaa aacagctaat ttcatattag
    55141 aactccaaat taattcctgg taagtctaat gcaatttcag tcacttcgta agtcaaacga
    55201 ttgagcatgt tcaaacatgg acgagccaag gtttccacct cttcttggtt caattcactt
    55261 ggttcattga caatacggcc atcgatatgg tttacttgtg agattgttcc actaatgaca
    55321 aacttatcaa atacaatcat aaagctcaag atgacaatca aggaagtcac ttgattttct
    55381 tggtcatgtt ggagcaattg gaaattcaca tccaccttgg tttcaggagc tccattttca
    55441 ttttcccatt caaaattacg cgcatcaaaa tgatactgac taacaaattc ttgttcacgt
    55501 ttaagattca tgtctttctc catcggctac aatattataa gctattgtac cataattttt
    55561 tattttcatc tagttttcta ggatttagtc aatcccaatt tcagcacgaa ctacatctgt
    55621 gatggtatca acatagtagt ttacttcttc tgttgtaggc gcttctgcca taacacgcaa
    55681 gaggggttct gttccacttg gacgaacaag gatacggccg ttccccgcca tttcttcttc
    55741 catcttctcg atgatggcct tgatagctgg cacttccatg gccttttcct tcatgacgtt
    55801 ttccactcgg atattaacta atttttgtgg ataaatcgtt acttctgccg ccaactctga
    55861 taagctctta ccagtttcct tcatgatttt agtcaattga actgctgata attgaccatc
    55921 acctgtggta ttgtaatcca tcaagataac gtgaccagac tgttcaccac caaggttgta
    55981 gcctgatttt ctcatttctt caacaacgta gcggtcacca actgcagtaa ctgccttgtt
    56041 aataccttcg cgattcaagg ccttgtggaa accaaggtta gacataacag ttgtcacaat
    56101 tgtattttga gccaattgtc ctttttcaga aaggtatttt ccgatgatgt acataatctt
    56161 gtcaccatca acgatgtcac cattctcatc aacagcaatc aagcggtcac tgtctccatc
    56221 aaaggccaaa ccaatagctg acccactttc tttgaccact tcttgaaggg cttctggatg
    56281 tgttgaacca acattaaggt tgatgttaag accgtctggt gtttccccga taaccgtcaa
    56341 ttgggcacca aggtctgcaa agatttgacg ggcactggta gaagctgctc cattagctgt
    56401 atccaaggca accttcattc catcaagagg agttccagtt gaaacaaggt atccttcata
    56461 cttacgcaag ccttctggat aatctaccaa aattcctaag ccttctgcac ttggacgagg
    56521 aagagtgtct tcctcagcat ctagcaaggc ttcaatttct gcttcttttt catcatctag
    56581 tttgaagcca tcaccgccaa agaacttgat tccgttatca agggctgggt tgtggctagc
    56641 agaaatcatg acaccggcac ttgctccttc agtttcaacc aagtaagcta ctgctggtgt
    56701 tgcaaggaca ccaagtttgt atacgtgaat ccctactgaa aggagacctg ccaccaaggc
    56761 cgattccaac atttcccctg aaatacgtgt gtcacgtcct acaaagactt tcggcgcttc
    56821 cgtttcatgt tgactaagaa catagcctcc aaaacgtcct agtttaaagg ctaattctgg
    56881 tgttagttct aggttagctt ctccacggac tccatcagtc ccaaaatatt tacccattgt
    56941 tataaaatcc ttttctattt ttaattcgtt tttgaactag ttgctttcgt tgacgaagat
    57001 gtctccgatg aactgcttgt acttgaattt gatgtgcttg aacttggtgc tactggtttt
    57061 gtagtcacct tcattattgt atcaaacgga gtgataactg ccggtaagac aacaccattg
    57121 cggtcgattg cctgcaaagg tactgaacca ctgtaattac ctgttatacg ttcgctagtt
    57181 ggcaaaacag cgataatctt atcaattcta tccaatgtct cttggtcact cgtaatagac
    57241 acttctttat ctgacaccat gacattttca atttgtaccc gactatcaat ttgactaggg
    57301 tcaatctctg gtacaatctt taccttatcc ttctgagcct tcttaccaat cttgactgta
    57361 attttttgcg gagtcgccac agcggtcagc ccattgggta aatcttcaat gctcaaagga
    57421 acttcaatcg ttccaacacc ggcatctgtt aggtcagcag taaccttgaa tttacgtgta
    57481 ctttcttgca tttcactagc tagcgatagg cgatttgcac cagtcaagac cactgatact
    57541 tctgaagcaa aaccgctaat aaaatactta tcactattat agcgtatgtc aatagggaca
    57601 tttgttactg tattagtata ggtttccgtt tttacctgcc tagcactggt actgttttga
    57661 aaattcgtcg ccgtagcata gacaaataag acacaagcaa aaaagagtga ggatatgata
    57721 tataaactat tttttttcat gtttccatcc tcctagcaat cgttctttaa aactaagacc
    57781 cacttcctct tttggaagta agatttcacg taattctgtt tcaaattcat caagtgttag
    57841 gttgtgctta aaccttccat tataggttat cgaaattcct cccgtttcct ctgatacgac
    57901 aaaagtcaag gcatctgaga cttctgataa accgatagcc gcccggtgtc tggtcccaaa
    57961 ttccttggaa atccctgtgt tttttgtcaa gggcagatag gcagacgtca cagcgatacg
    58021 ttcttctttg ataatcaccg caccatcatg taggggagtg ttgggaataa aaatgttaat
    58081 gagaagttct gcagaaatct tagcatccaa gggaattcct gtcgaaatat actcctgcaa
    58141 ggtacgtaca cgctgaatag caaccaaggc cccgatttta cgaggactca tgtattcaac
    58201 agacttaaca aaggcacgaa tcatctgttc ctcagcacta ataggggcat tggaaaagaa
    58261 atctgtcgct cttcccaaac gttccaaacc agtccgaatc tctggagaga agataacaac
    58321 cgccgcaata accccataag taataatttg attgattaac caagaaatcg tagtcaaacc
    58381 aatcatattt gcaaggattt gagctaaaat aaacaccaaa actccacgta ccaaaatcat
    58441 aatcttggtt cctgcaatag cttttgtaaa atggtataaa atataagcaa caatcaaaat
    58501 atcaatcaga ttgatagcta tcgtccatgg acttgcaaac aaactggtcc aatattgcag
    58561 attggataat tgttgaaaat tcatccctga tatcctccct atcaaaacac tttcgtccta
    58621 ttataccatt ttctggcatt tttttcccta tcctagtcca ttttacattg aacaaaaata
    58681 tgataaaata aactgactaa aaaaaacaaa ggagaaacta tgtctcaact ctatgatatt
    58741 accattgtgg gtggtggtcc tgtcgggctt tttgcagcct tttatgccca cctacgccaa
    58801 gccaaggttc aaatcatcga ctctcttccc cagctaggtg gacaacctgc tattctctac
    58861 cctgaaaagg aaatcctaga cgtaccaggc ttcccaaacc tgactggaga agagttgact
    58921 aaccgcttga ttgaacagct aaatggattt gataccccta ttcatctcaa tgaaacggtt
    58981 cttgagattg acaaacaaga agaatttgcc atcacaactt ctaaaggaag tcacctgact
    59041 aaaacagtta tcatcgctat gggtggcggt gccttcaaac cacgtccgct ggaacttgaa
    59101 ggggttgagg gctatgaaaa tatccactac cacgtttcta acattcagca atacgctggt
    59161 aagaaagtga cgattcttgg tgggggagac tcggctgtgg attgggcttt ggcttttgaa
    59221 aaaatcgcac caactaccct tgttcaccgc agagataatt tccgtgcctt ggaacacagt
    59281 gttcaagcct tgcaagaatc atctgtaacc atcaagacac cattcgcccc tagccaactc
    59341 cttggaaatg gaaaaacact tgataaactt gaaatcacaa aagtcaaatc tgatgaaact
    59401 gaaaccattg acctagacca cctctttgtc aactatggtt tcaaatcttc tgtcggtaac
    59461 cttaaaaact gggggctcga cctcaaccgt cacaagatta tcgtcaacag caaacaggaa
    59521 tccagccaag caggtatcta tgctatcggt gactgctgct actatgacgg aaaaattgat
    59581 ctgattgcga caggcctcgg agaagctcca actgctgtca acaacgctat caactacatt
    59641 gaccctgaac aaaaagtaca accaaaacac tctactagtt tataaaaaag aaccacgagt
    59701 cacataggat tcgtggtttt ataattcatc cgctatctta ttgatttttc tgagtctgtg
    59761 attgacacca cttttggtca gaggggtgct gagactatct gctaactgct ggatagagta
    59821 gtctgggtgc tgaatcctca gttgcgccac ttcctgcaaa tctactggca aattttctaa
    59881 gcccatgata tctttgattt tactgatatt gttaatggtc ttcatgctgg cagaaactgt
    59941 ccgagcgata ttagctgtct cggcattatt agcccgattg aggtcgttac gggtttctcg
    60001 caaaatctta acccgctcaa aatcatcacg tgcctgcatg gctcctatta ctatcaagaa
    60061 gtccataatg tcttctgctc gctggagata ggtcacagcc cccttcttgc gctcaagcac
    60121 cttggcatcc agtaaaaact gttggagaag ggaggcaatt ccttgcgcgt ggtccagata
    60181 aacagaactg atttccaact ggtacttgcc tgactcaggg tcacgaatgc tcccatttgc
    60241 caagaaagcg ccacagagat aggcacgacc tgcttcctca tccgataaaa tcgcctcatc
    60301 aatacctgtt tccaggccaa agaaagagtc tgccaagtgc aaatcactta acaaatcctg
    60361 caccttttca tctgtaaaaa cggtatagac gcgattcttg cgaagattgc tccgttggtg
    60421 gtgacgaatt tcagatttga tttcatagag atggagaaag gactcataga ggtgacgggc
    60481 cagtttggca ttttctgtca caactgacaa agtcaagccc gaagtcgaga gaccgatgct
    60541 accagacatt ttgataatgg cagataattc atgccagctc agatggtgtt ggcccaggat
    60601 ttcttctttt actgctactg tgaaactcat tttttcacct gtataatgcg catcaactcg
    60661 tccacaatca aatctccatc gtggaaggca ccgccatttt ccagacgaag gaagttagat
    60721 gaaatcacgc gcgaaacttg cttacaaaga cctacaaaat cgtgttccac ttgcactaag
    60781 tattcatcaa aacggttgga attcatgtat tcctgaggca ctttttcaat attcaccaag
    60841 acagtgtcga taaaagggcg accaaggtga cgatgcaaga cttccacgtg gtcgctatct
    60901 gtaaagtgtt ccgtctcccc acgttgggtc atgatattgc agacataggc aatttctgcc
    60961 ttggtttcca aaagagcccg cccaatttcc ttaatcacga tattgggcaa aatagaggta
    61021 aagagggaac ctggccctag gacaatcatg tcactttcaa ggatggtctg cactactcga
    61081 cggctggcca gaggcgtatc atcgtttagg gcattggtca catagacatt gtcaattatg
    61141 cctcgatggt ctacaatatg actctctcca gccacttctg tcccatcctg aaagactgca
    61201 tgaagggtca aaggatggtc actggaagga taaattttcc ctgttgtatg gaaaaatttg
    61261 ctcaataact gcatggcatt ataggttgaa ccctgcattt ctgacaagcc agcaatgatg
    61321 agatttccca atggatggcc agcaaaggct ccggcatcct cagagaaccg atactgaaag
    61381 accttctcat aaaacttagg catatccgac atggccacaa ggacattacg aagatcacct
    61441 ggcggtgtca actgttgcat attttttcgg agttcacctg aagaaccacc atcatctgcc
    61501 accgtcacga tagctgcgat ttccacatct ttttcccgca gactttttag aatgacggga
    61561 cttccagtcc ctccaccaat caccgttatc tttggttttc tcatgaacgg tttaccgttt
    61621 cctttctgcg gtctttgtcg cgatgccctt cattaacaga ccaattcttg gataagtcct
    61681 gcgccaagcg tttagcaaat gccacactac ggtgttgtcc acccgtacat cccatggcaa
    61741 tggtcaaaac ggacttacct tccttttggt aacttggcag aatcggctca atcaaggcca
    61801 ataaatgttg ataaaagtct tctgactcag gatggttcat gacataatca taaacaggtt
    61861 catccacacc cgtttggttt ctcagttctg gtaaataata gggatttggc aagaaacgga
    61921 catcaaagac caagtccgca tcaatcggga ttccatactt aaatccgaaa gacatgactt
    61981 cgatacggaa agactgggct tgttcttggt ctgaaaactg ctctgcaagg gttttgcgca
    62041 gctcacgtgg agtgagttca gtcgtatcca ccacattttg gctcatattt ttcaaaggtg
    62101 ccaagagttc acgttccaac ttgattccat ctaaaatacg accgtctgct gctagtgggt
    62161 gactccgtct ggtttccttg taacgagcga ccaattcctt atcagccgca tccaaaaaga
    62221 ggattttgaa atccaaacca tcttgatttt ccaactcatc caaaacagct tgaatctctg
    62281 aaaagaaaga acggctacgc atatccacta ccaaggccaa cttaggattg tcttccttaa
    62341 tttcaaccag ctgcaaaaac ttaggcaaga gagctggcgg catattatca atggtgaaat
    62401 aacctagatc ctcgaaggac tgaatggcta cagttttccc tgcgccactc atccctgtca
    62461 caatcaccaa gtgaagttgt ttctttgtca tctttttctc cttatatcaa aagaagtttg
    62521 gcaacaccaa acttcaacta gcttatccaa tctctgcgat gacttcaatt tcgactttta
    62581 catcacgagg aagacgagct acctccacag ctgaacgagc tgggaattcc tctttgaagg
    62641 ccgtttggta aacctcatta aaaggaacaa agtcgttcat atcgctcaag aagcaagttg
    62701 ttttgacaac atggtcaaag tctgttcctg cttctgccaa aatagcaccg atgtttttca
    62761 agacttgctc tgtctgttct tggatattct ctcctacaat ttccccagtt tcaggggata
    62821 ggggaacttg accgctagca aacaaaaggt tgccaacgat ttttccttga acatagggtc
    62881 cgatagcctt tggggcctta tctgtatgaa ttgtttttgc cattttcttt tcctcacaat
    62941 ttttctaaga ttgcatccca agcctcatcc atccctgcct tactgacaga tgaaaagagg
    63001 atgaaatcgt cactcgggtc aaagtttaat ttctttttga ttgctgattc atgcttgttc
    63061 catttaccac gaggaatctt gtccgccttg gtcgccacaa tgatgactgg aatctcataa
    63121 tacttgagaa attcgtacat ctgcacatca tctgctgacg ggtcatgacg aaggtcaact
    63181 agactgacaa ccgcacggag attttcccga gtcgttaagt actcctcaat catgcacccc
    63241 cacttttcac gttccttttt agaaacacga gcatagccat aaccaggcac atccacaaag
    63301 cgcatcttgt catcaatgtt aaaaaagttc aggagctggg ttttaccagg ttttcctgat
    63361 gtacgggcga gattcttacg gttcaacata gtgttgataa agctggattt accaacattt
    63421 gaacgccctg ctagggcaat ctctggcagt tcatcctgcg gatagtggga cttattagct
    63481 gcactgagca agatttcagc attgtgtgta ttaagttcca tagtcacctc taggctgttt
    63541 ctaggatcgg tttatccgtt ccatctacag tttctttagt gatgcgaacc aatttcacat
    63601 tttcctgact cggcacctca aacatgacat ctagcatggt ttcttcgatg atggagcgaa
    63661 gtccacgcgc ccctgtcttc cgttcgattg ctttattagc aatctcttga agggcttcgt
    63721 cgtcaaattc caactcaaca tcatcataag aaagcaaggt ttggtattgt ttcaccaagg
    63781 catttcttgg ctctttcaag atgcgaacca agtcatcaac ggtcaattgc tcaagagccg
    63841 caaaaacagg caagcgtcca atcaactcag ggataatacc aaatttttga atgtcttcag
    63901 cgatgatttc ttgcatgtat gagctgtttt cgtcaatcgc cttattattt tgaccaaatc
    63961 cgatgacttt ttcacccaga cgttgtttga caatttcttc aataccatca aaagcaccac
    64021 ccacgatgaa gaggatattt tttgtatcca cttgaatcat ctcttgttgt ggatgtttgc
    64081 gtccaccttg aggcggtacg ctagcaacag ttccctcaat aatcttgaga agggcttgtt
    64141 gcaccccttc accagaaaca tcacgtgtga tagacacatt ctcactcttc ttggcaatct
    64201 tgtcaatttc atccacatag ataatgccac gctctgcacg ttcgatgtta aagtcagcaa
    64261 cctgcaagag tttgaggagg atattttcca catcctcacc cacataacca gcctccgtca
    64321 gagctgtcgc atccgcaata gcaaaaggta cattcaagct cttagccaag gtctgggcaa
    64381 ggaaagtttt ccctgaacca gttgggccaa tcatcaaaat gtttgacttc tgcaaatcca
    64441 catcttctga ctcttcgcgt gtatcgtgga aattgatgcg tttgtagtgg ttataaaccg
    64501 ccactgccaa ggcacgcttg gcacgatctt gaccaattac atagtggttc aagatatgga
    64561 ggagttcaat tggttttggc acctcagaca agtctgccaa gacttcctca accaattctt
    64621 ctcgaatgat ttcctgagct aactccacgc attcattaca aataaaagca ttgttgccag
    64681 caattatttt ttgtacttct tcttggtttt tgccacaaaa tgagcaataa accatcatat
    64741 cattttttct atttgtagac atgatttcct tccattctat actgtcattc tatctaaaat
    64801 aaggtcatgt aaaaagcatg aatactattg accagattgg taaaggcatt taaccaaagg
    64861 aggatagaaa gcccgtaacg ctttttacga aaagcttgtg ctcctgccag aaagcagatg
    64921 aaacacagaa aagccgtgaa tagaccaaat aaactccgtt ccattagact tcctttctct
    64981 tgcggtattg gatggtaaaa tcataaggat tcttctcatc tttggcgtaa aatttgcttg
    65041 aaactgtctc aaaaagagac aagtcaagtt cttcagggaa ataggtatct ccttccaccc
    65101 gagcatgaat gtgagtgaca atcacttcat caaggtaagg ttcaaaagcc tgaaaaattt
    65161 gcttcccacc gataatgtag agattctttt cttgagcctg ataccagtca agaacagact
    65221 ggacgtcctg aaaagtagca accccatcta tcttttcttc cggattacgc gtcaaaatca
    65281 aggtttcccg ttttggaagc aagcgacgcc ccatcccatc aaaggtcaca cgccccatca
    65341 agatagcatg attcagagtt gtttctttaa agtgctgcaa ttctgctggc aaatgccaag
    65401 gcagacgatt ttccttacca atcacaccct cttcatcctg ggcccaaata gctacgattt
    65461 tcttagtcat gcttccatcc ttttcactga tagtactatt ttatcaaaaa actcaaaaaa
    65521 agactggttt ggaatagctt acaaaataga aaaaatctgt aagaaatttc ctacagattt
    65581 atctatgttt ccttatttct tacaaaccag gtgcttgtcc aagttcggct gcaagcatcc
    65641 aaattgtttt atctgtttca gttttagcgc ctgcaaagat accgtttgtc acatcgtcac
    65701 cttcttcatc agtgacatcc aaaccttttt ggaaaagttc tgacaagtaa cggtagataa
    65761 caagaacacg ttccaagctt tcttcaacat tacggtattc accagcttct tcttcgattt
    65821 cactattttg aaggaactct gtcaatgtag agaatgggct tccaccgagt gtaatcaagc
    65881 gttcactgat ttcatccaat tgaccgtcaa gagcttccat gtactcatcc atttttggat
    65941 gccatacaag gaaaccacga ccatgcatat accagtgcac ttggtgcaaa gcaacgtgag
    66001 ctacatacaa atcagcaaca gcttggttca agacttcctt tgtttttgcc aatgctactg
    66061 gcgctgcttt tgtcaatgat gttacgtctt ttactgcttc ttttttcaat tctaccattt
    66121 tctttacctc attcattatt ttttgtaacc acttcttaat gattactacc ttagtatact
    66181 actaaggaaa accaatagca agacaaagaa cttatatgag aaaagttgca atagactgat
    66241 aatttaagaa ttctttagaa gacaaaaaga gggttggatg cttatagtca atggaaatcc
    66301 atcagcaaac taggaaacta aacccagctt gaccaaagca caagttttga ggtcgcaggt
    66361 agaactgacc aagctgatgt ggtttgaaga aattccccaa tactataata gattgaaata
    66421 agatgaaacc aagtcgatta ggaaaggtaa atgaatttct aaaatgtttt accaatcaca
    66481 aggtatttgt ctatattcaa tctactatat aagcttcatt tccgagcaag aacttgaatt
    66541 tactcgagga tgaactatca taaaacaaag aaaaagaggg tgctactatc acatccctct
    66601 ttcaaatcat cgcttaatac caaacgctga catctacgcg cccttggatt cctttcatgt
    66661 attcagaaga ggtatattgc caaccttttt ttcctgaata atgagggttt tcccattcta
    66721 aagcattcgt ataggccgct acccagttta catgttttaa aatatctggg tgttttaaac
    66781 gcgtctgtaa taaactacga tagctataga catacacatt ttgataaccc gcctgcttca
    66841 tcgtgtccat gtacttgttg atgattttaa cccaagtgcc tgtatcactt ggagctctct
    66901 tgctcttatt tacatattcc caattctcaa catcataata gatagggtaa gacaggttca
    66961 tattgtattt ctttataagt tcaatggtct gtttagcgtc actctcagca tcggtctcat
    67021 tttcagcata ggtatagaga tagacaccat aaggaattcc cagacggttt aactccttaa
    67081 tgttatgcgc caattccttg tcttctttac cgctataacc tagacgaaca atgacaccat
    67141 ccacttcgtt ctcatcaata acctttttcc aatcattgat acgaccattg tgctcactaa
    67201 tatcaatgac tttcttagca tgttcggttc ccacttgttc ttctctatta ttaaagaaat
    67261 agcgcttacc atctctgtga acccagccga cattcaaatc ttttttttct ttgagctcac
    67321 cagaggccgc aaagatatag cgagtaccat ccataatcac ttcgtcagtc gccatggcac
    67381 cacttccagt caaatagtag ttgccttgcc actcattccg agccatatag ccccacttct
    67441 tgaaatagta ccatttgccg cccacttttt gccactcttg gttagcataa gttccatcgg
    67501 attttagata aaaataagca gaataggctg gatcatagag ccattcattt tgcatcatag
    67561 ctccttgacc attcaagaaa taacttcctt gccattggct tttagccatg taaccccact
    67621 tcttgaagta gtaccactta tttccaatca attgccattc ttgatgagca taagccccat
    67681 ctgacttgag ataaaaccaa ctcttgtaat tactgtcata gatccactcg ttttgggcca
    67741 tatatccacc tgatttcagg tagtaatttc catgccattc attctgcgag taacgaccat
    67801 ctgaattaat ataaaaccaa gccttatagt agttgtcaaa aatccattca ctttgagctt
    67861 tagaaccatc atcctttaca taataatccc catcccagtg ggcagcagca ttagtctgta
    67921 cttctgcgct cgtttgcgtt ttattagaag actgattttg ctctgaacta cttgaagctg
    67981 tcgttgtatc ctgcgaagtt tttgctactt cagtttcatt tgcagcgaca tgactagttg
    68041 ccaagcctag taaacagata cttgctaatc caatttttgt tttcaatctt tctctcctat
    68101 aaaaaatgta acagacatct gaatgctgtt ccacctagct tttgctactt actgattatt
    68161 ttacaaagtc aagcaaagcc aagaagcttt cagcttcaag tgacgcacca cctacaaggg
    68221 caccgtcaac gtctgggcaa gccatgtatg aagcaacatt ttcaggttta acagaaccac
    68281 cgtattgaac acgaactttg tctgcgactt cttgaccaaa gtcagcagct acaacgtcac
    68341 gaacaacttt acacattttt tgtgcatcgt cttgtgaagc tgatttacca gtaccgatag
    68401 cccagattgg ctcataagcg ataactgagg cagcaacttg ttcagcagtc aatccagcca
    68461 atgcagcaga tacttgagca cctacgaatt cagcagcttt accagcttcg taagtttcaa
    68521 gtgattcacc acaacagatg attggaagca taccgttcgc aaagattgct tttgcttttt
    68581 tgttgatatc ttcatcagtt tcatggaagt agtcacggcg ttctgagtga ccgataacaa
    68641 cgtagtcagt accgatttct ttcaaaactt gtgggctagt ttcaccagtg aaagcacctg
    68701 cattttcaaa gtagcagttt tgagcagcaa ctttaaggtt tgagcctttt gcaacagcaa
    68761 gaacagttgt caaatcaaga gctggagcag cgatacctgc ttcaacaaga tctgatgaag
    68821 gaagttttga tgcaactgct tcaacgaatg ctttagcttc ttctggattt ttgttcattt
    68881 tccagttacc agcgataaat ggtttacgtg acatttcaca tacctctttt ttcaatttat
    68941 tttctattta ttctatcaca attatacaca gcttgcaaat cttactcgga tttcaagcct
    69001 acttgcatgg attaatcctt ccagagatcc atggcattta tgaaatctgc agatacctgt
    69061 gtcaactgag gattgcttgc ttctctttct gctctcttgg cctcaatttg agccacactc
    69121 ttgattcctt catggcgcca gtttctcaaa atcgcctgaa tgtacttcca gtttggtttt
    69181 ccattcaaaa cagcttcacg aagagcctcc ttaatcaagt cagcactggt tccatcttcc
    69241 tttagtgtct tggtcaaatc ctcaatctca aaaggcgtca acaatcgtcc caactcctgc
    69301 tggaaggttt ccaccaaatc cttgagctgg ttttgaggtg ttagctggtc tgaacttgaa
    69361 tgaactgctc caaacaggtc atccaaacgt tccaaggcca aactagcatc aaagagcaat
    69421 tcaatttcgc catttaattc gatagtacga tactggagca gtcccctttc cgtcagatta
    69481 gaaatggact ggttgacatc cgaaatttcc ttgccaatcc tttcagcaat ctggcttggc
    69541 gacatttctt ctaagcctgt cgtattttgc aaatagaaaa attgccaaac cagaaaatcg
    69601 tcgctagaag gaaagagttc cttaaaatgc aagagcaggg cactcggtaa aaccaaggta
    69661 cctgatttaa aagcgtctaa atatgtcata attcctctta taaataccca tatgcagatg
    69721 catcatcttc tatctttctc caatcaaaag gcgtctcctg atagaccgca tggtttaccc
    69781 aattactgaa aaagagggct gcagatgaag accaacaaag acaaggtacc tgattaacat
    69841 catcatcttt aaagtaattt tctggaatat gtgggtcgaa acctgcatca cgatctcgaa
    69901 aatactcttt tgccaaggta tcacggtcat actccaaatg accaaaacta taaatttctc
    69961 gtaaatcacg actggccaaa atagaaaccc caacctgagg tccttctgat aaaatctcga
    70021 gattggtctt gtttaagacc tcttccttag aaatctccgt gtgccgtgaa tgaggggata
    70081 catagctatc atcaaagcct ctaaatagaa ggtgaccctc ttttagggtg tcctgaggat
    70141 aaatacctga tagcttactg tccatctggt atttttctac accatagcgc agataaagcc
    70201 cagcctgagc cccccaacag atatgaaggg tcgaatagac atgagtctta gaccactcaa
    70261 gcatctgtct aaattcctcc caatagtcca cttcctcaaa tggtaaatgc tcaactggag
    70321 cacccgtgat gatcatccca tcaaaatact catccttgac ttcaggaaaa gttttataga
    70381 aggtctccat gtgctctgaa cgagttgttt tagaacggtg gctctccata tagagaaaat
    70441 caatatccag ttgtaggggt gtattagcca agtggcgcaa caactgggtc tctgtgacca
    70501 ttttctgtgg catgagattt aaaattaaaa tcttcaaagg acggatatct tggtgggcag
    70561 cacgttgatc atccatgaca aagatattct ctgtccgtaa aatctcaaca gctggcaatt
    70621 ttttatcaat tcgaatcggc ataaccctct cctaactgta ctctttcagg aataattgca
    70681 tatgtttgaa gacaaatctc aaacacttag tccttttatt atactgcaag aagatatagt
    70741 tttcaattat agtttttctc taactagtta tagtctattt ttatatccta gtgtagagaa
    70801 aacagcccta gggactgttt tcattaataa tgcataagaa ctttgtagtc gtagtcacca
    70861 attttttcac ggccgttcaa ttcatccaat tcaacaagga aggcacaacc tgccataaca
    70921 ccaccaagtt tttcaatcat ctcgatagtt gccttaacag ttccacctgt cgccaaaagg
    70981 tcatctacaa taagaacacg ttgacctggc ttaatggcat ccgcgtgcat agtcaaggta
    71041 tcgacaccgt actctttttc atagtcagca gaaataactt cgcgtggcaa tttacctggc
    71101 ttacgaacag gcgcaaaacc aattcccaac tcaaaggcaa ctggacaacc cacgataaat
    71161 ccacgagctt caggtcccac gatcatgtcg actttcttgt cagtagcata ctgaacgatt
    71221 tcacgaacag cgtagctata agcatttcca tcagccatca aaggactaat atcacggaag
    71281 gtaatgcctt cctttggata attttcaatt gttgcaatgt aatcttttaa attcatcttt
    71341 ttctttcttt caaagttttt tactctctat tatagcatat tttttaagaa agaaaaaagg
    71401 aaaagttaac ttcaataatt atctaacgtt ttgacgattt ataactagcc atcgcaataa
    71461 agcccaattt ctgtttattc ttagcaaaca ttttatacat agttaaaaac tgctttctat
    71521 tctccttttt acaagcattt acacaaattt tcaaagttcc tagcaaacct tcgtcataaa
    71581 tcatacccga taatttcatt aatgtcattt caccagtcaa tgctttcaca tcacaataac
    71641 ctgattctat catcacctgt tcccaaccat cttgagttaa aggacctaca tttacatgaa
    71701 ttgcttgtga taattcctgt ctgatagact ctttagcttc cttaagaagc acatcatgtg
    71761 tcaagagaag acctccaggt tttaataccc ttagatattc cattacacat tttttcttag
    71821 cttgatcggc ttgcatagtc agcatagctt catttataac aatatcaaaa ctagcatctt
    71881 gataaggaag tttcattgca tttgctcttt caaaactgat taaatgagca acacctgccg
    71941 ttccagcaga ttttttagcc acttctaaag cttgagcatc catatcaaca gcagttatct
    72001 tgcaaccaaa acgctgtgcc aactcaattg ctgtagttcc cctattacac gcaacctcta
    72061 gtattctctt ttcttttgaa aatcctcctt ctgcaattaa ccaatctgtg gcacgctttc
    72121 cacctggacg taagcgtttt ttccccaatt ttgctaaaaa cttatgacct gcttctgaca
    72181 tttgaacacc tctgtttttt cttcattata acacaaaatg atattatctg acaattctaa
    72241 tctattattt gataaactag aatcaaaagc atacaagtca ccataactat agcataaatt
    72301 tattattacc tctctagttc gaattcaatt gctcacgtag tttacgcata tagcttcact
    72361 tgtagatggt acccacaaat aatactcaat ggaaatcaaa gagcaaacta ggaaactagc
    72421 cgtaagctgc tcaaagtaca tctttgaggt tgcagataaa actgacgaaa tcagtaatca
    72481 tacgtacggc aaggcgacgt tgacgtggtt tgaagagatt ttcgaagagt attaaagagc
    72541 atcacaatat agatgcataa tatgacttct ctagcaaaaa ggagagaagc attttgtttc
    72601 tctccctaga ttaactgata tctctccact acaattgata aagagatatc ttttcttgta
    72661 gtgctttgaa ttttatttat tttagtagat tgttttttca gtttctacat cgaagaagtg
    72721 tgctttgttc aagtcaaatc caagctcaac tgttgcacct gtttgcaagt agtcacgagc
    72781 atcaactttt gcaacaaact cgtctttacc aacttgacag taaaggtgag attctgaacc
    72841 aagcagttct gatacagaga tagtcgcttt tacaacacag tctgggaatg tttcaaggaa
    72901 agcaggttct gcattcacgt cttctggacg gataccaaag atcaattctt ttccttcgta
    72961 gcctttttca cgaagaactt tcaatgctcc ttctggcact ttcaaacgga aaccgtcaga
    73021 aacaatttcg ctaccaacca atttcacggt gatgaagttc atagctgggc ttccgatgaa
    73081 tcctgcaacg aatttgttaa ctggattttt gtaaacttct tgaggagtac cgatttgttc
    73141 tacacgtccg atagtacctg taccagcagg gttcttagta gctgacataa taacgatacg
    73201 gtctgcaagt gtcatcgctt ctgtttggtc gtgagttaca tagatagttg tagctccgat
    73261 acgacggtga attttagcga tttcagcacg cattgataca cgaagtttgg catccaagtt
    73321 tgacaaaggt tcgtccatca agaatacttt cgcatcacgg acaatcgcac gccccatggc
    73381 aacacgttga cgttgaccac ctgaaaggtc agctggttta cgttccaaga attctttcaa
    73441 tccaagtatt tcagctgctt cttgaacacg tttgttaatg tcttctttgc tgtatttacg
    73501 caatttcaaa ccgaaagcca tgttgtcata aacagtcatg tgtgggtaaa gagcgtagtt
    73561 ttggaatacc atggcgatat cacggtcttt tggagctacg tcgttgacaa ctacgccatc
    73621 gatagatgca gtaccttctg taatgtcttc aagaccagca atcatacgga gtgtagttga
    73681 tttaccacat cctgaaggtc ctacgaaaac gataaattct ttatctttga tgttcaagtt
    73741 gaaatcttca actgaatagt gttcgctgtt tggatatttt ttgtaaatat ttttaagatt
    73801 caattctacc atgaggtgaa ctccttttgt cttttgataa ttatattata tatgaaaacg
    73861 ctttatattt ctatggcaag atgaccaaaa aaataaacaa gttctgtgca acttgcacaa
    73921 aactttagag aatatcggag aatttgaaga agataatctt tattattctt ctatagacaa
    73981 aagcagaaac aaggatcagt tttcccatat tttcgggctc tataatattt gtagtgggta
    74041 aatcccctat ggatattatg gagcttattt ttgtgtagaa aaaaagtccc atatgaccta
    74101 taatgaaaag cgacaaaaca actcattaga aagaatcata tggaacaatt acattttatc
    74161 acaaaactgc tcgatattaa agacccaaac atcaagattc tagatatcat caatatggat
    74221 acccacaaag aaattatcgc taagctggat tatgaggctc catcttgccc tgattgtgga
    74281 agtctaatga agaaatatga ctttcaaaaa ccgtctaaga tcccttacct cgaaacaact
//
LOCUS       DAVFER010000004        66081 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1105170250
            SAMEA2167659-rid19724873.denovo.004, whole genome shotgun sequence.
ACCESSION   DAVFER010000004 DAVFER010000000
VERSION     DAVFER010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2167659
            Sequence Read Archive: ERR388902
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 66081)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 66081)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928716.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928716.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 04:07:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,118
            CDSs (total)                      :: 2,073
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 120
            CDSs (without protein)            :: 120
            Pseudo Genes (ambiguous residues) :: 0 of 120
            Pseudo Genes (frameshifted)       :: 67 of 120
            Pseudo Genes (incomplete)         :: 47 of 120
            Pseudo Genes (internal stop)      :: 34 of 120
            Pseudo Genes (multiple problems)  :: 23 of 120
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..66081
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2167659-rid19724873.denovo.004"
                     /strain="1105170250"
                     /db_xref="taxon:1313"
     gene            complement(28..825)
                     /locus_tag="VU534_000258"
                     /pseudo
     CDS             complement(28..825)
                     /locus_tag="VU534_000258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436304.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            1091..1327
                     /locus_tag="VU534_000259"
     CDS             1091..1327
                     /locus_tag="VU534_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecX"
                     /protein_id="HEU1512913.1"
                     /translation="MLQKIYEQMANFYDSIEEEYGPTFGDNFDWEHVHFKFLIYYLVR
                     YGIGCRKDFIVYHYRVAYRLYLEKLVMNRGFISC"
     gene            1558..2844
                     /locus_tag="VU534_000260"
     CDS             1558..2844
                     /locus_tag="VU534_000260"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HEU1512914.1"
                     /translation="MTSVVVVGTQWGDEGKGKITDFLSANAEVIARYQGGDNAGHTIV
                     IDGKKFKLHLIPSGIFFPEKISVIGNGMVVNPKSLVKELSYLHEEGVTTDNLRISDRA
                     HVILPYHIELDRLQEEAKGDNKIGTTIKGIGPAYMDKAARVGIRIADLLDKDIFRERL
                     ERNLAEKNRLFEKLYDSKAIVFDDIFEEYYEYGQQIKKYVIDTSVILNDALDNGKRVL
                     FEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGVGPSKIDKVVGVCKAYTSRVGDGP
                     FPTELFDEVGERIREVGHEYGTTTGRPRRVGWFDSVVMRHSRRVSGITNLSLNSIDVL
                     SGLDTVKICVAYDLDGQRIDYYPASLEQLKRCKPIYEELPGWSEDITGVRNLEDLPEN
                     ARNYVRRVSELVGVRISTFSVGPGREQTNILESVWS"
     gene            3045..3512
                     /locus_tag="VU534_000261"
     CDS             3045..3512
                     /locus_tag="VU534_000261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deaminase"
                     /protein_id="HEU1512915.1"
                     /translation="MYYTLEEKEVFMREALREAEIALEHDEIPIGCVIVKDGEIIGRG
                     HNAREELQRAVMHAEIMAIEDANLSEESWRLLDCTLFVTIEPCVMCSGAIGLARIPNV
                     VYGAKNQKFGAAGSLYNILTDERLNHRVEVEIGILEDECAAIMQDFFRNRRKK"
     gene            3545..3642
                     /gene="ffs"
                     /locus_tag="VU534_000262"
     ncRNA           3545..3642
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="VU534_000262"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            3699..4142
                     /locus_tag="VU534_000263"
     CDS             3699..4142
                     /locus_tag="VU534_000263"
                     /EC_number="3.6.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HEU1512916.1"
                     /translation="MKIRGFELVSSFTDENLLPKRETAHAAGYDLKVAVRTVVAPGEI
                     VLVPTGVKAYMQPTEVLYLYDRSSNPRKKGLVLINSVGVIDGDYYGNPGNEGHIFAQM
                     KNITDQEVVLEVGERIVQAVFATFLIADGDAADGVRTGGFGSTGH"
     gene            4144..4659
                     /locus_tag="VU534_000264"
     CDS             4144..4659
                     /locus_tag="VU534_000264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEU1512917.1"
                     /translation="MKIIFVRHGEPDYRELEERSYIGFGIDLAPLSEMGRQQVQKLSK
                     NPLLSSAEIIVSSAVTRALETASYVVCATGLPLRVEPLLHEWQVYKTGIENFETARRL
                     FLENKGELLPNSPIQYETATEMKSRFLECMSKYREHQTVVVVAHRMLMRQFVPNEKID
                     FCQVIECELEI"
     gene            4673..6034
                     /gene="radA"
                     /locus_tag="VU534_000265"
     CDS             4673..6034
                     /gene="radA"
                     /locus_tag="VU534_000265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000336571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HEU1512918.1"
                     /translation="MAKKKATFVCQNCGYNSPKYLGRCPNCGSWSSFVEEVEVAEVKN
                     ARVSLTGEKTKPMKLAEVTSINVNRTKTEMEEFNRVLGGGVVPGSLVLIGGDPGIGKS
                     TLLLQVSTQLSQVGTVLYVSGEESAQQIKLRAERLGDIDSEFYLYAETNMQSVRAEVE
                     RIQPDFLIIDSIQTIMSPEISGVQGSVSQVREVTAELMQLAKTNNIAIFIVGHVTKEG
                     TLAGPRMLEHMVDTVLYFEGERHHTFRILRAVKNRFGSTNEIGIFEMQSGGLVEVLNP
                     SQVFLEERLDGATGSSIVVTMEGTRPILAEVQALVTPTMFGNAKRTTTGLDFNRASLI
                     MAVLEKRAGLLLQNQDAYLKSAGGVKLDEPAIDLAVAVAIASSYKDKPTNPQECFVGE
                     LGLTGEIRRVNRIEQRINEAAKLGFTKIYVPKNSLTGITLPKEIQVIGVTTIQEVLKK
                     VFA"
     gene            6107..6604
                     /locus_tag="VU534_000266"
     CDS             6107..6604
                     /locus_tag="VU534_000266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase"
                     /protein_id="HEU1512919.1"
                     /translation="MSYFEQFMQANQAYVALHGQLNLPLKPKTRVAIVTCMDSRLHVA
                     QALGLALGDAHILRNAGGRVTEDMIRSLVISQQQMGTREIVVLHHTDCGAQTFENEPF
                     QEYLKEELGVDVSDQDFLPFQDIEESVREDMQLLIESPLIPDDVIISGAIYNVDTGSM
                     TVVEL"
     gene            6629..6838
                     /locus_tag="VU534_000267"
     CDS             6629..6838
                     /locus_tag="VU534_000267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1512920.1"
                     /translation="MKKSNILFIFILLLCIGLQYETIYYTDGSRSGAEYGLMGVSIFL
                     ALFYMIPALYFLFRIGKNGNCQRRF"
     gene            6820..7443
                     /locus_tag="VU534_000268"
     CDS             6820..7443
                     /locus_tag="VU534_000268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrsW family intramembrane metalloprotease"
                     /protein_id="HEU1512921.1"
                     /translation="MPKKVLILSLLGGMFLSGWLSSFANTYIHDLLGVLFPDSPFLNA
                     FESAIAAPLVEEPLKLLSLVFVLALIPVRKLKSLFLLGIASGLGFQMIKDIGYIRTDL
                     PEGFDFTISRILERIISGIASHWTFSGLAVVGVYLLYRAYKGQKVGKKQGLIFLGLAL
                     GTHFLFNSPFVELETELPLAIPVVPAIALYGFYHAYCFVEKHNELMT"
     gene            7588..8556
                     /locus_tag="VU534_000269"
     CDS             7588..8556
                     /locus_tag="VU534_000269"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006149122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HEU1512922.1"
                     /translation="MSFSDLKLFALSSNKELAERVAQEIGIELGKSSVRQFSDGEIQV
                     NIEESIRGKHVFILQSTSSPVNDNLLEILIMVDALKRASAESVNVVMPYYGYARQDRK
                     ARAREPITSKLVANMLEVAGVDRLLTIDLHAAQIQGFFDIPVDHLMGAPLIADYFERR
                     GMVGSDYVVVSPDHGGVTRARKLAEFLKTSIAIIDKRRSVDKMNTSEVMNIIGKVEGK
                     TCILIDDMIDTAGTICHAADALAEAGAVEVYASCTHPVLSGPATDNIQKSAIKKLVVL
                     DTIYLPEERLIDKIEQISIAHLLGDAIVRIHEKRPLSPLFDIEKKI"
     gene            complement(8690..8971)
                     /locus_tag="VU534_000270"
                     /pseudo
     CDS             complement(8690..8971)
                     /locus_tag="VU534_000270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(9098..9331)
                     /locus_tag="VU534_000271"
     CDS             complement(9098..9331)
                     /locus_tag="VU534_000271"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1512923.1"
                     /translation="MFSQLHMREEQVLLAQDYALETARAEGLEQGLERGKVEGRAERK
                     LFAFLDIVRQGLLTSEVASQQLGMSVSEFEALL"
     gene            complement(9324..9440)
                     /locus_tag="VU534_000272"
     CDS             complement(9324..9440)
                     /locus_tag="VU534_000272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000233180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein CinA"
                     /protein_id="HEU1512924.1"
                     /translation="MVGVFRQQALYPATATSHYPSKSTAGLQELVRGGQENV"
     gene            complement(9655..10005)
                     /locus_tag="VU534_000273"
     CDS             complement(9655..10005)
                     /locus_tag="VU534_000273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family transposase"
                     /protein_id="HEU1512925.1"
                     /translation="MLRHPGISPTNDLIAKKIFSNPEITCQFIRDMLDLPAKNVTILE
                     GSDIHVLLSMPYSVQDFYTSIDVLAELDNGTQVIIEIQVHHQNFFINHLWAYLCSQVN
                     QNLEKIRQREGDTH"
     gene            10261..12894
                     /gene="polA"
                     /locus_tag="VU534_000274"
     CDS             10261..12894
                     /gene="polA"
                     /locus_tag="VU534_000274"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014932012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HEU1512926.1"
                     /translation="MDKKKLLLIDGSSVAFRAFFALYQQLDRFKNVAGLHTNAIYGFQ
                     LMLSHLLERVEPSHILVAFDAGKTTFRTEMYADYKGGRAKTPDEFREQFPFIRELLDH
                     MGIRHYDLAQYEADDIIGTLDKLAEQDGFDITIVSGDKDLIQLTDEHTVVEISKKGVA
                     EFEAFTPDYLMEEMGLTPAQFIDLKALMGDKSDNIPGVTKVGEKTGIKLLLEHGSLEG
                     IYENIDGMKTSKMKENLINDKEQAFLSKTLATIDTKAPIAIGLEDLVYSGPDVENLGK
                     FYDEMGFKQLKQALNVSSADVSESLDFTIVDQISQDMLSEESIFHFELFGENYHTDNL
                     VGFVWSCGDKLYATDKLELLQDPIFKDFLEKTSLRVYDFKKVKVLLQRFGVDLQAPAF
                     DIRLAKYLLSTVEDNEIATIASLYGQTYLVDDETFYGKGVKKAIPEREKFLEHLACKL
                     AVLVETEPILLEKLSENGQLELLYDMEQPLAFVLAKMEIAGIMVKKETLLEMQAENEL
                     VIEKLTQEIYELAGEEFNVNSPKQLGVLLFEKLGLPLEYTKKTKTGYSTAVDVLERLA
                     PIAPIVKKILDYRQIAKIQSTYVIGLQDWILADGKIHTRYVQDLTQTGRLSSVDPNLQ
                     NIPARLEQGRLIRKAFVPEWEDSVLLSSDYSQIELRVLAHISKDEHLIKAFQEGADIH
                     TSTAMRVFGIERPDDVTANDRRNAKAVNFGVVYGISDFGLSNNLGISRKEAKAYIDTY
                     FERFPGIKNYMDEVVREARDKGYVETLFKRRRELPDINSRNFNIRGFAERTAINSPIQ
                     GSAADILKIAMIQLDKALVAGGYQTKMLLQVHDEIVLEVPKSELVEMKKLVKQTMEEA
                     IQLSVPLIADENEGATWYEAK"
     gene            12979..13416
                     /locus_tag="VU534_000275"
     CDS             12979..13416
                     /locus_tag="VU534_000275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HEU1512927.1"
                     /translation="MSQEFINPSDGVIRQYLATSKTLAVVGLSDREETTSNRVTKEMQ
                     ARGYKIIPVNPKAAGGEILGEKAYASLAEIPFPVDIVNVYRRSEFLPDVARDFLKADA
                     KIFWAQLGLESLEAKEILRDGGCDDIVMNRCIKREHTRLIEEA"
     gene            13457..13534
                     /locus_tag="VU534_000276"
                     /pseudo
     CDS             13457..13534
                     /locus_tag="VU534_000276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(13735..14745)
                     /locus_tag="VU534_000277"
     CDS             complement(13735..14745)
                     /locus_tag="VU534_000277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YeiH family putative sulfate export transporter"
                     /protein_id="HEU1512928.1"
                     /translation="MSFLSKNGAGILACLLISILSWYLGGFFPVVGAPVFAIFIGMLL
                     HPFLSSYKQLDAGLTFSSKKLLQYAVVLLGFGLNISQVFAVGQSSLPVILSTISIALI
                     IAYLFQRFFALDTKLATLVGVGSSICGGSAIAATAPVIDAKEKEVAQAISVIFFFNVL
                     AALIFPTLGTWLHLSNEGFALFAGTAVNDTSSVTAAASAWDSLYQSNTLESATIVKLT
                     RTLAIIPITLFLSYWQSRQQENKQSLQLKKVFPLFILYFILASLLTTLLTSLGVSSSF
                     FTPLKELSKFLIVMAMSAIGLKTNLVAMVKSSGKSILLGAICWIAIILTTLGMQTLIG
                     IF"
     gene            14894..16063
                     /locus_tag="VU534_000278"
     CDS             14894..16063
                     /locus_tag="VU534_000278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEU1512929.1"
                     /translation="MDLTKRFNKQLDKIQVSLIRQFDQAISEIPGVLRLTLGEPDFTT
                     PDHVKEAGKRAIDQNQSYYTGMSGLLTLRQAASDFVKEKYQLDYAPENEILVTIGATE
                     ALSATLTAILEEGDKVLLPAPAYPGYEPIVNLVGAEIVEIDTTENGFVLTPEMLEKAI
                     LEQGDKLKAVILNYPANPTGITYSREQLEALAAVLRKYEIFVVCDEVYSELTYTGEAH
                     VSLGTMLRDQAIIINGLSKSHAMTGWRLGLIFAPATFTAQLIKSHQYLVTAANTMAQH
                     AAVEALTAGKNDAEPMKKEYIQRRDYIIEKMTALGFEIIKPDGAFYIFAKIPAGYNQD
                     SFAFLKDFAQKKAVAFIPGAAFGRYGEGYVRLSYAASMETIKEAMKRLEEYMREA"
     gene            16060..16830
                     /gene="recO"
                     /locus_tag="VU534_000279"
     CDS             16060..16830
                     /gene="recO"
                     /locus_tag="VU534_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000616164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HEU1512930.1"
                     /translation="MIQSITSQGLVLYNRNFREDDKLVKIFTEQVGKRMFFVKHAGQS
                     KLAPVIQPLVLARFLLRINDDGLSYIEDYHEVMTFPKINSDLFVMAYATYVAALADAS
                     LQDNQQDAPLFAFLQKTLELMEAGLDYQVLTNIFEIQILTRFGISLNFNECVFCHRVG
                     QAFDFSFKYGACLCPEHYHEDKRRCHLNPNIPYLLNQFQAIDFETLETISLKPGIKQE
                     LRQFMDQLYEEYVGIHLKSKKFIDSLADWGQLLKEEKK"
     gene            16827..17819
                     /gene="plsX"
                     /locus_tag="VU534_000280"
     CDS             16827..17819
                     /gene="plsX"
                     /locus_tag="VU534_000280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000717456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HEU1512931.1"
                     /translation="MKKIAVDAMGGDYAPQAIVEGVNQALSDFSDIEVQLYGDEAKIK
                     QYLTATERVSIIHTDEKIDSDDEPTRAIRNKKNASMVLAAKAVKDGEADAVLSAGNTG
                     ALLAAGFFIVGRIKNIDRPGLMSTLPTVDGKGFDMLDLGANAENTAQHLHQYAVLGSF
                     YAKNVRGIAQPRVGLLNNGTESSKGDPLRKETYELLAADESLNFIGNVEARDLMNGVA
                     DVVVADGFTGNAVLKSIEGTAMGIMGLLKTAITGGGLRAKLGALLLKDSLSGLKKQLN
                     YSDVGGAVLFGVKAPVVKTHGSSDAKAVYSTIRQIRTMLETDVVAQTAREFSGE"
     gene            17825..18058
                     /locus_tag="VU534_000281"
     CDS             17825..18058
                     /locus_tag="VU534_000281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HEU1512932.1"
                     /translation="MTEKEIFDRIVTIIQERQGEDFVVTESLSLKDDLDADSVDLMEF
                     ILTLEDEFSIEISDEEIDQLQNVGDVVKIIQGK"
     gene            18104..18394
                     /locus_tag="VU534_000282"
                     /pseudo
     CDS             18104..18394
                     /locus_tag="VU534_000282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            18597..18827
                     /gene="blpU"
                     /locus_tag="VU534_000283"
     CDS             18597..18827
                     /gene="blpU"
                     /locus_tag="VU534_000283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpU"
                     /protein_id="HEU1512933.1"
                     /translation="MNTKTMSQFEIMDTEMLACVEGGGCNWGDFAKAGVGGGAARGLQ
                     LGIKTRTWQGAATGAVGGAILGGVAYAATCWW"
     gene            19542..21695
                     /locus_tag="VU534_000284"
     CDS             19542..21695
                     /locus_tag="VU534_000284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000668284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter"
                     /protein_id="HEU1512934.1"
                     /translation="MKFGKRHYRPQVDQMDCGVASLAMVFGYYGSYYFLAHLRELAKT
                     TMDGTTALGLVKVAEEIGFETRAIKADMTLFDLPDLTFPFVAHVLKEGKLLHYYVVTG
                     QDKDSIHIADPDPGVKLTKLPRERFEEEWTGVTLFMAPSPDYKPHKEQKNGLLSFIPI
                     LVKQRGLIANIVLATLLVTVINIVGSYYLQSIIDTYVPDQMRSTLGIISIGLVIVYIF
                     QQILSYAQEYLLLVLGQRLSIDVILSYIKHVFHLPMSFFATRRTGEIVSRFTDANSII
                     DALASTILSIFLDVSTVVIISLVLFSQNTNLFFMTLLALPIYTVIIFAFMKPFEKMNR
                     DTMEANAVLSSSIIEDINGIETIKSLTSESQRYQKIDKEFVDYLKKSFTYSRAESQQK
                     ALKKVAHLLLNVGILWMGAVLVMDGKMSLGQLITYNTLLVYFTNPLENIINLQTKLQT
                     AQVANNRLNEVYLVASEFEEKKTVEDLSLMKGDMTFKQVHYKYGYGRDVLSDINLTVP
                     QGSKVAFVGISGSGKTTLAKMMVNFYDPSQGEISLGSVNLNQIDKKALRQYINYLSQQ
                     PYVFNGTILENLLLGAKEGTTQEDILRAVELAEIREDIERMPLNYQTELTSDGAGISG
                     GQRQRIALARALLTDAPVLILDEATSSLDILTEKRIVDNLIALDKTLIFIAHRLTIAE
                     RTEKVVVLDQGKIVEEGKHADLLAQGGFYAHLVNS"
     gene            21708..23057
                     /locus_tag="VU534_000285"
     CDS             21708..23057
                     /locus_tag="VU534_000285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyD family secretion protein"
                     /protein_id="HEU1512935.1"
                     /translation="MKPEFLESAEFYNRRYHNFSSSVIVPMALLLVFLLGFATVAEKE
                     MSLSTRATVEPSRILANIQSTSNNRILVNHLEENKLVKKGDLLVQYQEGAEGVQAESY
                     ASQLDMLKDQKKQLEYLQKSLQEGENHFPEEDKFGYQATFRDYISQAGSLRASTSQQN
                     ETIASQNAAASQTQAEIGNLISQTEAKIRDYQTAKSAIETGASLAGQNLAYSLYQSYK
                     SQGEENPQTKVQAVAQVEAQISQLESSLATYRVQYAGSGTQQAYASGLSSQLESLKSQ
                     HLAKVGQELTLLAQKILEAESGKKVQGNLLDKGKVTASEDGVLHLNPETSDSSMVAEG
                     ALLAQLYPSLEREGKAKLTAYLSSKYVARIKVGDSVRYTTTHDAGNQLFLDSTITSID
                     ATATKTEKGNFFKIEAETNLTSEQAEKLRYGVEGRLQMITGKKSYLRYYLDQFLNKE"
     gene            23227..23934
                     /locus_tag="VU534_000286"
     CDS             23227..23934
                     /locus_tag="VU534_000286"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000043309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HEU1512936.1"
                     /translation="MSKQLIYSGKAKDIYTTEDENLIISTYKDQATAFNGVKKEQIAG
                     KGVLNNQISSFIFEKLNVAGVATHFVEKLSDTEQLNKKVKIIPLEVVLRNYTAGSFSK
                     RFGVDEGIALETPIVEFYYKNDDLDDPFINDEHVKFLQIAGDQQIAYLKEETRRINEL
                     LKVWFAEIGLKLIDFKLEFGFDKDGKIILADEFSPDNCRLWDADGNHMDKDVFRRGLG
                     ELTDVYEIVWEKLQELK"
     gene            23936..24079
                     /locus_tag="VU534_000287"
     CDS             23936..24079
                     /locus_tag="VU534_000287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HEU1512937.1"
                     /translation="MFATENLRLSTKRTQAEKVPQTFSLCRELGELTDVYEIVWEKLQ
                     GLK"
     gene            24136..27861
                     /locus_tag="VU534_000288"
     CDS             24136..27861
                     /locus_tag="VU534_000288"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000361233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase"
                     /protein_id="HEU1512938.1"
                     /translation="MDKRIFVEKKADFQVKSESLVRELQHNLGLSSLKSIRIVQVYDV
                     FDLAEDLFAPAEKHIFSEQVTDHVLDEVSVQADLANYAFFAIESLPGQFDQRAASSQE
                     ALLLLGSSSDVTVNTAQLYLVNKDIDATELEAVKNYLLNPVDSRFKDITTGIAKQEFS
                     ESDKTIPKLTFFESYAAEDFARYKAEQGMAMEVDDLLFIQDYFKSIGRVPTETELKVL
                     DTYWSDHCRHTTFETELKHIDFSASKFQKQLQSTYDKYIAMREELGRSEKPQTLMDMA
                     TIFGRYERANGRLDDMEVSDEINACSVEIEVDVDGVKEPWLLMFKNETHNHPTEIEPF
                     GGAATCIGGAIRDPLSGRSYVYQAMRISGAGDITAPISETRAGKLPQQVISKTAAHGY
                     SSYGNQIGLATTYVREYFHPGFVAKRMELGAVVGATPKGNVVREKPEAGDVIILLGGK
                     TGRDGVGGATGSSKVQTVESVETAGAEVQKGNAIEERKIQRLFRNGNVTRLIKKSNDF
                     GAGGVCVAIGELADGLEIDLNKVPLKYQGLNGTEIAISESQERMAVVVRPEDVDAFVA
                     ECNKENIDAVVVATVTEKPNLVMHWNGETIVDLERRFLDTNGVRVVVDAKVVDKDVKL
                     PEERQTSAETLESDTLTVLSDLNHASQKGLQTIFDCSVGRSTVNHPLGGRYQLTPTEA
                     SVQKLPVQHGVTHTASVIAQGFNPYVAEWSPYHGAAYAVIEATARLVAAGANWFKARF
                     SYQEYFERMDKQAERFGQPVAALLGSIEAQIQLGLPSIGGKDSMSGTFEELSVPPTLA
                     AFGVTTADSRKVLSPEFKAVGENIYYIPGQALSAEIDFDLIKKNFAQFEAIQADHKVT
                     SASAVKYGGVVESLALATFGNYIGAEVTLPELETALTAQLGGFVFTSPEEIAGVEKVG
                     QTKADFTLTVNGVKLDGHKLDSAFQGTLEEVYPTEFTQAKELEEVPAVASDVVIKAKE
                     KVEKPVVYIPVFPGTNSEYDSAKAFEKEGAEVNLVPFVTLNEEAIVKSVETMVDNIDK
                     TNILFFAGGFSAADEPDGSAKFIVNILLNEKVRVAIDSFIARGGLIIGICNGFQALVK
                     SGLLPYGNFEAANSTSPTLFYNDANQHVAKMVETRIANTNSPWLVGVQVGDIHAIPVS
                     HGEGKFVVTAEEFAELRDNGQIFSQYVDFNGKPSMDSKYNPNGSVHAIEGITSKNGQI
                     IGKMGHSERYEDGLFQNIPGNKDQHLFASAVKHFTGK"
     gene            27954..29396
                     /locus_tag="VU534_000289"
     CDS             27954..29396
                     /locus_tag="VU534_000289"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000220605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HEU1512939.1"
                     /translation="MTYEVKSLNEECGVFGIWGHPDAAKLTYFGLHSLQHRGQEGAGI
                     LSNDQGQLKRHRDMGLLSEVFRNPANLDKLTGAGAIGHVRYATAGEASVDNIQPFLFR
                     FHDMQFGLAHNGNLTNAASLKKELEQRGAIFSATSDSEILAHLIRRSHNPSLMGKIKE
                     ALSLVKGGFAYILLFEDKLIAALDPNGFRPLSIGKMANGAVVVSSETCAFEVIGAEWI
                     RDLKPGEIVIIDDEGIQYDSYTDDTQLAVCSMEYIYFARPDSNIHGVNVHTARKRMGA
                     QLAREFKHEADIVVGVPNSSLSAAMGFAEESGLPNEMGLIKNQYTQRTFIQPTQELRE
                     QGVRMKLSAVSGVVKGKRVVMVDDSIVRGTTSRRIVQLLKEAGATEVHVAIGSPALAY
                     PCFYGIDIQTRQELIAANHTVEETRQIIGADSLTYLSIDGLIESIGIETDAPNGGLCV
                     AYFDGDYPTPLYDYEEDYRRSLEEKTSFYK"
     gene            29615..30637
                     /locus_tag="VU534_000290"
     CDS             29615..30637
                     /locus_tag="VU534_000290"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HEU1512940.1"
                     /translation="MANKNAYAQSGVDVEAGYEVVERIKKHVARTERAGVMGALGGFG
                     GMFDLSKTGVKEPVLISGTDGVGTKLMLAIKYDKHDTIGQDCVAMCVNDIIAAGAEPL
                     YFLDYVATGKNEPAKLEQVVAGVAEGCVQAGAALIGGETAEMPGMYGEDDYDLAGFAV
                     GVAEKSQIIDGSKVVEGDVLLGLASSGIHSNGYSLVRRVFADYTGEEVLPELEGKKLK
                     EVLLEPTRIYVKAVLPLIKEELVNGIAHITGGGFIENVPRMFADDLAAEIDESKVPVL
                     PIFKTLEKYGQIKHEEMFEIFNMGVGLMLAVSPENVERVKELLDEAVYEIGRIVKKEN
                     ESVIIK"
     gene            30634..31179
                     /gene="purN"
                     /locus_tag="VU534_000291"
     CDS             30634..31179
                     /gene="purN"
                     /locus_tag="VU534_000291"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HEU1512941.1"
                     /translation="MKKIAVFASGNGSNFQVIAEEFPVEFVFSDHRDAYVLERAKQLG
                     VLSYAFELKEFESKADYEAALVELLEEHQIDLVCLAGYMKIVGPTLLSAYEGRIVNIH
                     PAYLPEFPGAHGIEDAWNAGVGQSGVTIHWVDSGVDTGQVIKQVRVPRLADDTIDRFE
                     ARIHEAEYRLYPEVVKALFTD"
     gene            31263..31772
                     /locus_tag="VU534_000292"
     CDS             31263..31772
                     /locus_tag="VU534_000292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000894002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HEU1512942.1"
                     /translation="MLESKKTTRYVFYVYLMLLTWGILFKFETNPEFIAFFLAPRYIN
                     WIPFSEPLIVDGKIVFAEMLFNLIFFIPLGVCFPLIKTNLSSLRIVGTGFLISLLFEC
                     LQYILAIGITDITDLTLNTLGVCVGLLIYQIFIRVFKSQTRKWINILGMLSLGFAYLV
                     LLLLHLLSV"
     gene            31797..33344
                     /gene="purH"
                     /locus_tag="VU534_000293"
     CDS             31797..33344
                     /gene="purH"
                     /locus_tag="VU534_000293"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006146083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HEU1512943.1"
                     /translation="MTKRVLISVSDKAGIVEFAQELKKLGWEIISTGGTKVALDNAGV
                     DTIAIDDVTGFPEMMDGRVKTLHPNIHGGLLARRDLDSHLEAAKDNKIELIDLVVVNL
                     YPFKETILKPDVTYADAVENIDIGGPSMLRSAAKNHASVTVVVDPADYAVVLDELAAN
                     GETSYETRQRLAAKVFRHTAAYDALIAEYFTAQVGESKPEKLTLTYDLKQPMRYGENP
                     QQDADFYQKALPTDYSIASAKQLNGKELSFNNIRDADAAIRIIRDFKDSPTVVALKHM
                     NPCGIGQADDIETAWDYAYESDPVSIFGGIVVLNREVDAATAEKMHGVFLEIIIAPSY
                     TDEALAILINKKKNLRILALPFNAQEASEVEAEYTGVVGGLLVQNQDVVKESPADWQV
                     VTKRQPTETEATALEFAWKAIKYVKSNGIIVTNDHMTLGVGPGQTNRVASVRLAIDQA
                     KDRLDGAVLASDAFFPFADNVEEIAKAGIKAIIQPGGSVRDQESIEAADKYGLTMVFT
                     GVRHFRH"
     gene            33466..34728
                     /gene="purD"
                     /locus_tag="VU534_000294"
     CDS             33466..34728
                     /gene="purD"
                     /locus_tag="VU534_000294"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000772208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HEU1512944.1"
                     /translation="MKLLVVGSGGREHAIAKKLLESKDVEKVFVAPGNDGMTLDGLEL
                     VNISISEHYKLIDFAKTNDVAWTFIGPDDALAAGIVDDFNQAGLKAFGPTRAAAELEW
                     SKDFAKEIMVKYGVPTATYGTFSDFEEAKAYIEKHGAPIVVKADGLALGKGVVVAETV
                     EQAVEAAHEMLLDNKFGDSGARVVIEEFLEGEEFSLFAFVNGDKFYIMPTAQDHKRAY
                     DGDKGPNTGGMGAYAPVPHLPQSVVDTAVDTIVKPVLEGVIKEGRPYLGVLYAGLILT
                     ADGPKVIEFNARFGDPETQIILPRLTSDFAQNITDILDSKEPNIMWTDKGVTLGVVVA
                     SKGYPLDYERGVELPAKTEGDVITYYAGAKFAENSRALLSNGGRVYMLVTTADTVKEA
                     QASIYQELYQQKIEGLFYRTDIGSKAIK"
     gene            35131..35619
                     /gene="purE"
                     /locus_tag="VU534_000295"
     CDS             35131..35619
                     /gene="purE"
                     /locus_tag="VU534_000295"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000805607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HEU1512945.1"
                     /translation="MKPVISIIMGSKSDWATMQKTAEVLDRFGVAYEKKVVSAHRTPD
                     LMFKHAEEARSRGIKIIIAGAGGAAHLPGMVAAKTTLPVIGVPVKSRALSGVDSLYSI
                     VQMPGGVPVATMAIGEAGATNAALFALRLLSVEDKSIADALANFAEEQGKIAEESSNE
                     LI"
     gene            35606..36697
                     /gene="purK"
                     /locus_tag="VU534_000296"
     CDS             35606..36697
                     /gene="purK"
                     /locus_tag="VU534_000296"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000099033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HEU1512946.1"
                     /translation="MSSSKTIGIIGGGQLGQMMAISAIYMGHKVIALDPAADCPVSRV
                     AEIIVAPYNDVDALRQLADRCDVLTYEFENVDADGLDAVIKDGQLPQGTDLLRISQNR
                     IFEKDFLSNKAQVTVAPYKVVTSSLDLADIDLSKNYVLKTATGGYDGHGQKVIRSEAD
                     LEAAYALADSADCVLEEFVNFDLEISVIVSGNGKEVTFFPVQENIHRNNILSKTIVPA
                     RISESLVDKAKAMAVRIAEQLNLSGTLCVEMFATADDIIVNEIAPRPHNSGHYSIEAC
                     DFSQFDTHILGVLGAPLPVIKLHAPAVMLNVLGQHVEAAEKYVTENPSAHLHMYGKIE
                     AKHNRKMGHVTLFSDVPDSVEEFGEGIDF"
     gene            36707..36934
                     /locus_tag="VU534_000297"
     CDS             36707..36934
                     /locus_tag="VU534_000297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazole carboxylase"
                     /protein_id="HEU1512947.1"
                     /translation="MIQIIVNTFIEKYKTGAVVEVLYASADQDKVQAKYEELAAQYPE
                     NYLAIYNVPLDTDLNTLDHYPSVFIGKEEFE"
     gene            36997..38295
                     /gene="purB"
                     /locus_tag="VU534_000298"
     CDS             36997..38295
                     /gene="purB"
                     /locus_tag="VU534_000298"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HEU1512948.1"
                     /translation="MINRYSRPEMANIWSEENKYRAWLEVEILSDEAWAELGEIPKED
                     VALIRKKADFDIDRILEIEQETRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTAY
                     GYLYKQANDIIRRDLENFTNIIADKAKEHKFTIMMGRTHGVHAEPTTFGLKLATWYSE
                     MKRNIERFEHAAAGVEAGKISGAVGNFANIPPFVEEYVCDKLGIRAQEISTQVLPRDL
                     HAEYFAVLASIATSIERMATEIRGLQKSEQREVEEFFAKGQKGSSAMPHKRNPIGSEN
                     MTGLARVIRGHMITAYENVALWHERDISHSSAERIITPDTTILIDYMLNRFGNIVKNL
                     TVFPENMIRNMNSTFGLIFSQRAMLTLIEKGMTREQAYDLVQPKTAYSWDNQVDFKPL
                     LEADSEVTSRLTQEEIDEIFNPVYYTKRVDDIFERLGLGD"
     gene            complement(38350..42288)
                     /gene="strH"
                     /locus_tag="VU534_000299"
     CDS             complement(38350..42288)
                     /gene="strH"
                     /locus_tag="VU534_000299"
                     /EC_number="3.2.1.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000679939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylhexosaminidase"
                     /protein_id="HEU1512949.1"
                     /translation="MKHEKQQRFSIRKYAVGAASVLIGFAFQAQTVAADGVTPTTTEN
                     QPTIHTVSDSPQSSENRTEETPKAVLQPEAPKTVETETPATDKVASLPKTEEKPQEEV
                     SSTPSDKAEVVTPTSAEKETANKKAEEASPKKEEAKEVDSKESNTDKTDKDKPAKKDE
                     AKAEADKPATEAGKERAATVNEKLAKKKIVSIDAGRKYFSPEQLKEIIDKAKHYGYTD
                     LHLLVGNDGLRFMLDDMSITANGKTYASDDVKRAIEKGTNDYYNDPNGNHLTESQMTD
                     LINYAKDKGIGLIPTVNSPGHMDAILNAMKELGIQNPNFSYFGKKSARTVDLDNEQAV
                     AFTKALIDKYAAYFAKKTEIFNIGLDEYANDATDAKGWSVLQADKYYPNEGYPVKGYE
                     KFIAYANDLARIVKSHGLKPMAFNDGIYYNSDTSFGSFDKDIIVSMWTGGWGGYDVAS
                     SKLLAEKGHQILNTNDAWYYVLGRNADGQGWYNLDQGLNGIKNTPITSVPKTEGADIP
                     IIGGMVAAWADTPSARYSPSRLFKLMRHFANANAEYFAADYESAEQALNEVPKDLNRY
                     TAESVTAVKEAEKAIRSLDSNLSRAQQDTIDQAIAKLQETVNNLTLTPEAQKEEEAKR
                     EVEKLAKNKVISIDAGRKYFTLNQLKRIVDKASELGYSDVHLLLGNDGLRFLLDDMTI
                     TANGKTYASDDVKKAIIEGTKAYYDDPNGTALTQAEVTELIEYAKSKDIGLIPAINSP
                     GHMDAMLVAMEKLGIKNPQAHFDKVSKTTMDLKNEEAMNFVKALIGKYMDFFAGKTKI
                     FNFGTDEYANDATSAQGWYYLKWYQLYGKFAEYANTLAAMAKERGLQPMAFNDGFYYE
                     DKDDVQFDKDVLISYWSKGWWGYNLASPQYLASKGYKFLNTNGDWYYILGQKPEDGGG
                     FLKKAIENTGKTPFNQLASTKYPEVDLPTVGSMLSIWADRPSAEYKEEEIFELMTAFA
                     DHNKDYFRANYNALREELAKIPTNLEGYSKESLEALDAAKTALNYNLNRNKQAELDTL
                     VANLKAALQGLKPAVTHSGSLDENEVAANVETRPELITRTEEIPFEVIKKENPNLPAG
                     QENIITAGVKGERTHYISVLTENGKTTETVLDSQVTKEVINQVVEVGAPVTHKGDESG
                     LAPTTEVKPRLDIQEEEIPFTTVTCENPLLLKGKTQVITKGVNGHRSNFYSVSTSADG
                     KEVKTLVNSVVAQEAVTQIVEVGTMVTHVGDENGQAAIAEEKPKLEIPSQPAPSTAPA
                     EESKVLPQDPAPVVTEKKLPETGTHDSAGLVVAGLMSTLAAYGLTKRKED"
     gene            complement(42616..43332)
                     /locus_tag="VU534_000300"
     CDS             complement(42616..43332)
                     /locus_tag="VU534_000300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001007200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEU1512950.1"
                     /translation="MAIPKYQYIKDELKNKIISGQFSSGDKFYTEAELISMYDVSSIT
                     VVRALNDLAKDGYIVRQQGKGTFVSRARKHKLVEFSDIELFNAKDDKVTVLSIERGNK
                     LVYLEKLGLRGDQFYYKIERIRESNGVVYIYHTSYIPEQYINANYPNLEYYSSIYNRF
                     KLDYHIHMNDEHFEEINEIVFPTPEHAASVLGVDEQFPTVLQTKITKLESTGQVLEYS
                     ETYKRSDYYKIKFISCDRDH"
     gene            43681..45468
                     /locus_tag="VU534_000301"
     CDS             43681..45468
                     /locus_tag="VU534_000301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase"
                     /protein_id="HEU1512951.1"
                     /translation="MTRFEIRDDFYLDGKSFKILSGAIHYFRVPPEDWYHSLYNLKAL
                     GFNTVETYVAWNLHEPCEGEFHFEGDLDLEKFLQIAQDLGLYAIVRPSPFICAEWEFG
                     GLPAWLLTKNMRIRSSDPAYIEAVGRYYDQLLPRLVPRLLDNGGNILMMQVENEYGSY
                     GEDKAYLRAIRQLMEECGVTCPLFTSDGPWRATLKAGTLIEEDLFVTGNFGSKAPYNF
                     SQMQEFFDEHGKKWPLMCMEFWDGWFNRWKEPIITRDPKELADAVREVLEQGSINLYM
                     FHGGTNFGFMNGCSARGTLDLPQVTSYDYDALLDEEGNPTAKYLAVKKMMATHFSEYP
                     QLEPLYKESMELDAIPLVEKVSLFETLDSLSSPVESLYPQKMEELGQSYGYLLYRTET
                     NWDAEEERLRIIDGRDRAQLYVDGQWVKTQYQTEIGEDIFYQGKKKGLSRLDILIENM
                     GRVNYGHKFLADTQRKGIRTGVCKDLHFLLNWKHYPLPLDNPEKIDFSKGWTQGQPAF
                     YAYDFTVEEPKDTYLDLSEFGKGVAFVNGQNLGRFWNVGPTLSLYIPHSYLKEGANRI
                     IIFETEGQYKEEIHLTRKPTLKHIKGENL"
     gene            45465..45941
                     /locus_tag="VU534_000302"
     CDS             45465..45941
                     /locus_tag="VU534_000302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HEU1512952.1"
                     /translation="MTIVGCRIDGRLIHGQVANLWAGKLNVSRIMVVDDEVVNNDIEK
                     SGLKLATPPGVKLSILPVEKAAANILGGKYDSQRLFIVARKPDRFLGLVEAGVPLETL
                     NVGNMSQTPETRSITRSINVVDKDVEDFHKLAEKGVKLTAQMVPNDPISDFLSLLK"
     gene            45969..46874
                     /locus_tag="VU534_000303"
     CDS             45969..46874
                     /locus_tag="VU534_000303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006149155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HEU1512953.1"
                     /translation="MIQWWQILLLTLYSAYQICDELTIVSSAGSPVFAGFITGLIMGD
                     VTTGLLIGGNLQLFVLGVGTFGGASRIDATSGAVLATAFSVSQGIDAPLAITTIAVPV
                     AALLTYFDVLGRMTTTFFAHRVDAAIERFDYKGIERNYLLGAIPWALSRALPVFFALA
                     FGGAFVQSVVDFVEAYKWVADGLTLAGRMLPGLGFAILLRYLPVKRNLHYLAMGFGLT
                     AMLTVLYSYVTGLGGAVAGIVGTLPAEVAEKIGFVNNFKGLSMIGISIVGIFLAVLHF
                     KNSQKVAVAAPSTPSESGEIEDDEF"
     gene            46861..47676
                     /locus_tag="VU534_000304"
     CDS             46861..47676
                     /locus_tag="VU534_000304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEU1512954.1"
                     /translation="MTNSNYKLTKEDFNHINKRSLFTFQLGWNYERMQASGYLYMILP
                     QLRKMYGDGTPELKEMMKVHTQFFNTSPFFHTIIAGFDLAMEEKDGVGSKDAVNGIKT
                     GLMGPFAPLGDTIFGSLVPAIMGSVAATMAIAGQPWGIFLWIAVAVAYDIFRWKQLEF
                     AYKEGVNLINNMQSTLTALIDAASVLGVFMMGALVATVINFEISYKLPIGEKMIDFQD
                     ILNQIFPRLLPAIFTAFIFWLLGKKGMNSTKAIGIIIVLALALSALGHFALGM"
     gene            47683..48087
                     /locus_tag="VU534_000305"
     CDS             47683..48087
                     /locus_tag="VU534_000305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007284837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEU1512955.1"
                     /translation="MTKSLILVSHGRFCEELRGSTEMIMGPQDNIYTVALLPEDGPEE
                     FTAKFEAVIEGLDDFLVFADLLGGTPCNVVSRLIMEGRDIDLYAGMNLPMVIEFINAS
                     LTGADADYKSRAAESIVKVNDLLAGFDDDEDE"
     gene            48386..49552
                     /locus_tag="VU534_000306"
     CDS             48386..49552
                     /locus_tag="VU534_000306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HEU1512956.1"
                     /translation="MLHYTKEDLLELGAEITTREIYQQPDVWREAFEFYQAKREEIAA
                     FLQEIADKHDYIKVILTGAGTSAYVGDTLLPYFKEVYDERKWNFNAIATTDIVANPAT
                     YLKKDVATVLVSFARSGNSPESLATVDLAKSLVDELYQVTITCAADGKLALQAHGDDR
                     NLLLLQPAVSNDAGFAMTSSFTSMMLTTLLVFDPTEFAVKSERFEVVSSLARKVLDKA
                     EDVKELVDLYFNRVIYLGAGPFFGLAHEAQLKILELTAGQVATMYESPVGFRHGPKSL
                     INDNTVVLVFGTTTDYTRKYDLDLVREVAGDQIARRVVLLSDQAFGLENVKEVALGCG
                     GVLNDIYRVFPYIVYAQLFALLTSLKVENKPDTPSPTGTVNRVVQGVIIHEYQK"
     gene            49668..50705
                     /locus_tag="VU534_000307"
     CDS             49668..50705
                     /locus_tag="VU534_000307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HEU1512957.1"
                     /translation="MKAYTERVFGNVEGEDVLAYRFETDGGYQLEVMTYGATILRYVA
                     PDKAGNFANVILGFDDFDSYVGNSPKHGASVGPVAGRIAGATFELNGKTYDLEVNNAS
                     NCNHSGSTGWDSSLFEVEEVSDHGLTLYTERTDGTGGFPGNLKIWISYHLEETGAYEI
                     SYKVTTDQDTLVNPTNHSYFNLSGDFTQTIDRHVFQLNTEGIYSIAPDGVPAKTPEAN
                     RDVVKHVYNGTLLKDIFAEEDEQIQLASGLDHPFALPAGHDNAGFLYDQNSGRFLLFK
                     TEAPCFVVYTANFVDESVIIGGQPMLQHNGIALEAQALPDAIHSDLKGQVILKAGQTF
                     TSKTRYELVVK"
     gene            50822..52035
                     /locus_tag="VU534_000308"
                     /pseudo
     CDS             50822..52035
                     /locus_tag="VU534_000308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041867.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein C"
     gene            52487..58057
                     /gene="zmpC"
                     /locus_tag="VU534_000309"
     CDS             52487..58057
                     /gene="zmpC"
                     /locus_tag="VU534_000309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000088129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metalloprotease ZmpC"
                     /protein_id="HEU1512958.1"
                     /translation="MSRKSIGEKRHSFSMRKLSVGLVSVTVSSFFLMSQGIQSVSADN
                     MESPIHYKYMTEGKLTDEEKSLLVEALPQLAEESDDTYYLVYRSQQFLPNTGFNPTVG
                     TFLFTAGLSLLVLLVSKRENGKKRLVHFLLLTSMGVQLLPASAFGLTSQILSAYNSQL
                     SIGVGEHLPEPLKIEGYQYIGYIKTKKQDNTELSRTVDGKYSAQRDSQPNSTKTSDVV
                     HSADLEWNQGQGKVSLQGEASGDDGLSEKSSIAADNLSSNDSFASQVEQNPDHKGESV
                     VRPTVPEQGNPVSATTVQSAEEEVLATTNDRPEYKLPLETKGTQEPGHEGEAAVREDL
                     PVYTKPLETKGTQGPGHEGEAAVREEEPAYTEPLATKGTQEPGHEGKATVREETLEYT
                     EPVATKGTQEPEHEGEAAVEEELPALEVTTRNRTEIQNIPYTTEEIQDPTLLKNRRKI
                     ERQGQAGTRTIQYEDYIVNGNVVETKEVSRTEVAPVNEVVKVGTLVKVKPTVEITNLT
                     KVENKKSITVSYNLIDTTSAYVSAKTQVFHGDKLVKEVDIENPAKEQVISGLDYYTPY
                     TVKTHLTYNLGENNEENTETSTQDFQLEYKKIEIKDIDSVELYGKENDRYRRYLSLSE
                     APTDTAKYFVKVKSDRFKEMYLPVKSITENTDGTYKVTVAVDQLVEEGTDGYKDDYTF
                     TVAKSKAEQPGVYTSFKQLVTAMQSNLSGVYTLASDMTADEVSLGDKQTSYLTGAFTG
                     SLIGSDGTKSYAIYDLKKPLFDTLNGATVRDLDIKTVSADSKENVAALAKAANSANIN
                     NVAVEGKISGAKSVAGLVASATNTVIENSSFTGKLIANHQDSNKNDTGGIVGNITGNS
                     SRVNKVRVDALISTNARNNNQTAGGIVGRLENGALISNSVATGEIRNGQGYSRVGGIV
                     GSTWQNGRVNNVVSNVDVGDGYVITGDQYAAADVKNASTSVDNRKADRFATKLSKDQI
                     DAKVADYGITVTLDDTGQDLKRNLREVDYTRLNKAEAERKVAYSNIEKLMPFYNKDLV
                     VHYGNKVATTDKLYTTELLDVVPMKDDEVVTDINNKKNSINKVMLHFKDNTVEYLDVT
                     FKENFINSQVIEYNVTGKEYIFTPEAFVSDYTAITNNVLSDLQNVTLNSEATKKVLGA
                     ANDAALDNLYLDRQFEEVKANIAEHLRKVLAMDKSINTTGDGVVEYVSEKIKNNKEAF
                     MLGLTYMNRWYDINYGKMNTKDLSTYKFDFNGNNETSTLDTIVALGNSGLDNLRASNT
                     VGLYANKLASVKGEDSVFDFVEAYRKLFLPNKTNNEWFKENTKAYIVEMKSDIAEVRE
                     KQESPTADRKYSLGVYDRISAPSWGHKSMLLPLLTLPEESVYISSNMSTLAFGSYERY
                     RDSVDGVILSGDALRTYVRNRVDIAAKRHRDHYDIWYNLLDSASKEKLFRSVIVYDGF
                     NVKDETGRTYWARLTDKNIGSIKEFFGPVGKWYEYNSSAGAYANGSLTHFVLDRLLDA
                     YGTSVYTHEMVHNSDSAIYFEGNGRREGLGAELYALGLLQSVDSVNSHILALNTLYKA
                     EKDDLNRLHTYNPVERFDSDEALQSYMHGSYDVMYTLDAMEAKAILAQNNDVKKKWFR
                     KIENYYVRDTRHNKDTHAGNKVRPLTDEEVANLTSLNSLIDNDIINRRSYDDNREYKR
                     NGYYTISMFSPVYAALSNSKGAPGDIMFRKIAYELLAEKGYHKGFLPYVSNQYGAEAF
                     ASGSKTFSSWHGRDVALVTDDLVFKKVFNGEYSSWADFKKAMFKQRIDKQDNLKPITI
                     QYELGNPNSTKEVTITTAAQMQQLINEAAAKDITNIDRATSHTPASWVHLLKQKIYNA
                     YLRTTDDFRNSIYK"
     gene            58413..59267
                     /locus_tag="VU534_000310"
     CDS             58413..59267
                     /locus_tag="VU534_000310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000220702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEU1512959.1"
                     /translation="MTYEYQSHIYLAEAVLNVKDLVSQTVFYQQIIGLEILSQTDTEV
                     VLGLGGKALVHLIQAQEGGEVREHYGLYHLAILLPTRKALADVLKHLTDLQIPLVGGA
                     DHGYSEALYLEDLEGNGIELYRDKPVSTWDIREDGRIIGVTEVLAAQDIYELGERVEP
                     FILAEGTRMGHIHLSVKDSRKSRQFYQTVLGLEDKFSVPSASWIAAGDYHHHLAVNEW
                     GGKGLDPRKQVLPGLAYYVIEVAHKEELLTIAQRAQEVDAPIKWMTSIQLEITDSDGI
                     VTRIRLAR"
     gene            59373..59930
                     /locus_tag="VU534_000311"
     CDS             59373..59930
                     /locus_tag="VU534_000311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000200249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar O-acetyltransferase"
                     /protein_id="HEU1512960.1"
                     /translation="MTSEYQKMIAGEFYRPSDPELRALAQASRQKQAAFNKEENPLKG
                     AEIIKTWFASTGKNLYINTRLMVDYGVNIHLGENFYSNWNLTMLDICPIRIGDNAMIG
                     PNCQFLTPLHPLDPQERNSGIEYGKPITIGDNFWTGGGVIVLPGVTLGNNVVAGAGAV
                     ITKSFGDNVVLAGNPARVIKEIPVK"
     gene            60147..60911
                     /locus_tag="VU534_000312"
     CDS             60147..60911
                     /locus_tag="VU534_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside phosphorylase"
                     /protein_id="HEU1512961.1"
                     /translation="MIQKHAIPILEFDDNPQAVIMPNHEGLDLQLPKKCVYAFLGEEI
                     DRYAREVGANCVGEFVSATKTYPVYVVNYKDEEVCLAQAPVGSAPAAQFMDWLIGYGV
                     EQIISTGTCGVLADIEENAFLVPVRALRDEGASYHYVAPCRYMEMQPEAIAAIEEVLE
                     DRGIPYEEVMTWTTDGFYRETAEKVAYRKEEGCAVVEMECSALAAVAQLRGVLWGELL
                     FTADSLADLDQYDSRDWGSEAFNKALELSLASVHHL"
     gene            61524..62903
                     /locus_tag="VU534_000313"
     CDS             61524..62903
                     /locus_tag="VU534_000313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000897732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HEU1512962.1"
                     /translation="MLFKLSKEKIELGLSRLSPARRIFLSFALVILLGSLLLSLPFVQ
                     VESSRATYFDHLFTAVSAVCVTGLSTLPVAHTYNIWGQIICLLLIQIGGLGLMTFIGV
                     FYIQSKQKLSLRSRATIQDSFSYGETRSLRKFVYSIFLTTFLVESLGAILLSFRLIPQ
                     LGWGRGLFSSIFLAISAFCNAGFDNLGSTSLFAFQTDLLVNLVIAGLIITGGLGFMVW
                     FDLAGHVGRKKKGRLHFHTKLVLLLTIGLLLFGTATTLFLEWNNAGTIGNLPVADKVL
                     VSFFQTVTMRTAGFSTIDYTQAHPVTLLIYILQMFLGGAPGGTAGGLKITTFFVLLVF
                     ARSELLGLPHANVARRTIAPRTVQKSFSVFIIFLMSFLIGLILLGITAKGNPPFIHLV
                     FETISALSTVGVTANLTPDLGKLALSVIMPLMFMGRIGPLTLFVSLADYHPEKKDMIH
                     YMKADISIG"
     gene            62917..63582
                     /locus_tag="VU534_000314"
     CDS             62917..63582
                     /locus_tag="VU534_000314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001283913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HEU1512963.1"
                     /translation="MSDRTIGILGLGIFGSSVLAALAKQDMNIIAIDDHAERINQFEP
                     VLARGVIGDITDEELLRSAGIDTCDTVVVATGENLESSVLAVMHCKSLGVPTVIAKVK
                     SQTAKKVLEKIGADSVISPEYEMGQSLAQTILFHNSVDVFQLDKNVSIVEMKIPQSWA
                     GQSLSKLDLRGKYNLNILGFREQENSPLDVEFGPDDLLKADTYILAVINNQYLDTLVA
                     LNS"
     gene            63892..64431
                     /locus_tag="VU534_000315"
     CDS             63892..64431
                     /locus_tag="VU534_000315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEU1512964.1"
                     /translation="MKLLSIAISSYNAAAYLHYCVESLVIGGEQVGILIINDGSQDQT
                     QEIAECLASKYPNIVRAIYQENKCHGGAVNRGLVEASGRYFKVVDSDDWVDPRAYLKI
                     LETLQELESKGQEVDVFVTNFVYEKEGQSRKKSMSYDSVLPVRQIFGWDQVGNFSKGQ
                     YTMMHSLIYRTDLLRASQF"
     gene            64498..64908
                     /locus_tag="VU534_000316"
     CDS             64498..64908
                     /locus_tag="VU534_000316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 2"
                     /protein_id="HEU1512965.1"
                     /translation="MYYLPVDFYRYLIGREDQSVNEQVMIKCIDQQLKVNRLLIDQLD
                     LSQVSHPKMREYLLNHIELTTVISSTLLNRSGTAEHLAKKRQLWTYIQQKNPEVFQAI
                     RKTMLSRLTKHSVLPDRKLSNVVYQITKSVYGFN"
     gene            65024..>66081
                     /gene="pavB"
                     /locus_tag="VU534_000317"
     CDS             65024..>66081
                     /gene="pavB"
                     /locus_tag="VU534_000317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding SSURE repeat adhesin PavB"
                     /protein_id="HEU1512966.1"
                     /translation="MKFNPNQRYTRWSIRRLSVGVASVVVASGFFVLVGQPSSVRADG
                     LNPTPGQVLPEETSGTKEGDLSEKPGDTVLTQAKPEGVTGNTNSLPTPTERTEVSEET
                     SPSSLDTLFEKDEEAQKNPELTDVLKETVDTADVDGTQASPAETTPEQVKGGVKENTK
                     DSIDVPAAYLEKAEGKGPFTAGVNQVIPYELFAGDGMLTRLLLKASDNAPWSDNGTAK
                     NPALPPLEGLTKGKYFYEVDLNGNTVGKQGQALIDQLRANGTQTYKATVKVYGNKDGK
                     ADLTNLVATKNVDININGLVAKETVQKAVADNVKDSIDVPAAYLEKAKGEGPFTAGVN
                     HVIPYELFAGDGMLTRLLL"
BASE COUNT        19001 a        12149 c        15479 g        19452 t
ORIGIN      
        1 agaggcgaga catttttcgg ttctttgtca actgtagtgg gttgaagaaa gcgaagatct
       61 agaaaggaca aatttcgtcc tttctttttt gaagttttca aagttcctaa aaccaaaggc
      121 attgtgcttg ataagtttga tgagattatt ggtggcttcc agtttggcgt tggaataagg
      181 taattgaagg gcgttgacga ttttctcttt atctttgagg aaggttttaa acaaagtctg
      241 aaacagaggt ggaaaagcaa gagctgatag agattatagt ggtgtttaaa gtcttcggaa
      301 tagctcaaaa gtttatctag aatttcttta ttagtcaagt gcatacgaaa agtagggcga
      361 taaaatcgtt tatcactcag tttctgacta tcttgttgaa tgagcttcca gtagcgcttg
      421 atagccttgt attcatggga tttcggatga tggcttgtgt tctgctctca agaacagtta
      481 tgatattgag tttatcaaag tcctgagcaa taaagctcat ctccatctcc cgattgaaac
      541 agtcactccc cggactgttt caacgtccta ggacataatc tcaggaagac gcgaaaaatc
      601 atgctcaaag tgaaaatcat tgttcttgcg aatgacagtt gaagttgaaa tagacaactg
      661 atgatcaatg tcggtcatag aagtcttttt aattagcttc tgagcaatct tttggttgat
      721 gatacaagga atttgatgat tcttcttgac gatagaagtc tcagcgagct ccatttttga
      781 gcaatgatag cacttaaaac ggccttttct aagaagaatt ctagtttgaa tttttttata
      841 ctagaaaatc agaaccataa tacctatata aaaatattat agttctaata ggatttaccc
      901 aaaagtttta aggcggtctt tttagaactt taattgtttg aaatttaggt agcaaatttg
      961 tttctatttt gtcaactttt cctattttta tcttgttgag gctggtattt taacaattca
     1021 ggaattgata gtgaatgtgt aaaatttttt gttagaataa gtttataaaa aagaaaagga
     1081 gtatttgatt atgttacaaa aaatttatga gcagatggct aatttctatg atagtattga
     1141 agaagagtat ggtcctacat ttggtgataa ttttgactgg gaacatgttc attttaaatt
     1201 tttaatttat tatttagtga gatatggcat tggttgtcgt aaggatttta ttgtttacca
     1261 ttatcgtgtt gcttatcgtt tgtatcttga aaaattggta atgaatcggg gttttatttc
     1321 ttgttgaggt aattttagta aatttccgaa ctaatttact cttttatgga aagatgatag
     1381 taaatagcta gtaatttttc taaatcattt tttaatagtt ggaaatagca aatctttcta
     1441 ttgtttcttc ttgataaaaa ggcgattttt tattataata aattgtaaga tataattgca
     1501 ggtgagagtc ctgccatgta tgtgagaaag gaagagcctg atggctcaga caagattatg
     1561 acttcagttg ttgttgtagg tacccaatgg ggtgatgaag gtaaagggaa gattacagac
     1621 ttcctttcag cgaatgcaga agtgattgca cgttaccaag gtggtgataa tgctggtcac
     1681 acgattgtga ttgacggtaa gaaatttaag ttgcacttga ttccatctgg gattttcttc
     1741 cctgaaaaaa tatctgtcat tgggaatggt atggttgtaa atcctaaatc tcttgtaaaa
     1801 gagttgagct atcttcatga ggaaggtgta acaactgata acttgcgtat ttctgatcgt
     1861 gcgcatgtta ttttgcctta tcatatcgag ttggatcgct tgcaagaaga agctaagggc
     1921 gacaataaga ttggtacgac aattaaggga attggtccag cttatatgga caaggctgct
     1981 cgtgttggaa ttcgtattgc agatctttta gataaagata ttttccgtga gcgtttagaa
     2041 cgtaaccttg ctgaaaagaa tcgtcttttt gaaaaattgt atgacagtaa agcgattgtt
     2101 ttcgatgata tttttgaaga atattacgaa tatggtcaac aaatcaagaa atacgtgata
     2161 gatacatctg ttatcttgaa tgatgcgctt gataatggca aacgtgtgct ttttgaaggt
     2221 gcacaaggtg ttatgctaga tatcgaccaa ggtacttatc catttgttac gtcatcaaac
     2281 cctgtagctg gtggtgtgac aattggttct ggtgtcggtc caagcaagat tgacaaggtt
     2341 gtaggtgtat gtaaagctta tacgagtcgt gtaggagatg gtcctttccc aactgagttg
     2401 tttgatgaag tgggagaacg tatccgtgaa gtgggtcatg aatatggtac aacaactggt
     2461 cgtccacgtc gtgtaggttg gtttgactca gttgtgatgc gtcatagccg tcgtgtttct
     2521 ggtattacta acctttcttt gaactctatt gatgttttga gcggtttgga tactgtgaaa
     2581 atctgtgtgg cctatgatct tgacggtcaa cgtattgact actatccagc tagtcttgaa
     2641 caattgaaac gttgcaagcc tatctatgaa gagttgccag gttggtcaga agatattacc
     2701 ggagttcgca atttggaaga tcttcctgag aatgcgcgta actatgttcg tcgtgtgagt
     2761 gaattggttg gcgttcgtat ttctactttc tcagtaggtc ctggtcgtga acaaacaaat
     2821 attttagaaa gtgtttggtc ctaagagatt tttaagattt gtttaagata ggtcgggtat
     2881 actatagacg gttacaagaa gacctcctaa cttgttgtaa caaatatcct aaacttttct
     2941 ttttcataat aatctcccta tagagtcacc gcattcggtg gctttttttg tgttgggatt
     3001 catgatataa taataaaatc gataagtagg aaaagagaaa agagatgtat tatacgcttg
     3061 aagaaaaaga agtctttatg agggaggctt tgagagaggc tgagattgct cttgaacacg
     3121 atgaaattcc aattggttgt gtgattgtca aagatgggga aatcattggt cgtgggcata
     3181 atgcgcgtga ggaattacag cgagcggtta tgcatgcgga aattatggct atagaggatg
     3241 cgaacttgag tgaggagagc tggcgcttgc tggattgcac actttttgtg accattgaac
     3301 cttgtgtcat gtgtagtgga gcgattgggc ttgcccgcat tccaaatgtg gtctatgggg
     3361 ctaaaaacca gaaatttggc gctgctggga gtttgtacaa tatcttgaca gatgagcgtc
     3421 tcaatcatcg tgtggaggtt gaaataggaa ttttggaaga tgaatgcgca gctatcatgc
     3481 aggatttttt tagaaataga cggaaaaaat aattttgctt ttaaaatgaa taggaatgtg
     3541 atataataaa tagtggagca acagttctgc gtgaagcggg tcaggggagg aatccagcag
     3601 ccctaagcga tttgaattgt gtgctctttt tttcgtgctt tttccgaata aataagatag
     3661 aataatctag aataaatgat aatagaaaag agaaaattat gaaaattcgt ggttttgaat
     3721 tggtttcgag ttttacagat gaaaatttat tgcccaagcg tgagacagcg catgcggctg
     3781 gttacgactt aaaggttgct gtgcgtacag ttgttgcgcc aggagagatt gtcttggttc
     3841 cgacaggggt taaggcttat atgcagccga ctgaggttct ctacctctat gatcgttctt
     3901 caaatcctcg taagaagggc ttggttttaa ttaactcagt tggagtcatt gatggggatt
     3961 attatggaaa tcctggaaat gaagggcata tttttgcgca gatgaagaat atcacagacc
     4021 aagaggttgt tcttgaagtt ggggagcgta ttgtccaggc tgtttttgct actttcttaa
     4081 ttgcagatgg agatgcagct gatggcgttc gaactggtgg atttggatcg acagggcact
     4141 agaatgaaga ttatctttgt acgtcatggg gagccagatt accgtgagtt agaggagcgt
     4201 tcttatatag gatttgggat agatttggca cccttgtctg agatgggacg gcagcaagtc
     4261 cagaaattga gcaaaaatcc tttactctcg tcagctgaaa taatcgtatc ttctgcagtc
     4321 acaagagctt tagaaacggc ttcgtatgtg gtctgtgcta cgggtcttcc tttaagagta
     4381 gagcctttat tacatgaatg gcaggtctat aaaacaggaa tagaaaactt tgaaacagct
     4441 agaagactgt ttttagaaaa caagggggag ttgcttccta atagtcctat tcaatatgag
     4501 acagctacgg aaatgaagtc tcggtttcta gaatgtatgt ctaagtatcg agaacatcag
     4561 actgtggtag ttgttgctca tcgaatgctc atgcgccagt ttgtgccaaa tgagaagatt
     4621 gatttttgcc aagtgattga gtgtgagtta gagatataga aagaggtttg tcatcgcaaa
     4681 gaaaaaagcg acatttgtat gtcaaaattg tgggtataat tcccctaaat atctgggacg
     4741 ttgccccaac tgtgggtctt ggtcttcttt tgtggaagag gttgaggttg ccgaagttaa
     4801 gaatgcgcgt gtgtccttga caggtgagaa aaccaagccc atgaaactag ctgaggtgac
     4861 ttccatcaat gtcaatcgaa ccaagacgga gatggaggaa ttcaaccgtg tgcttggagg
     4921 cggagtggta ccaggaagtc tcgtccttat cggtggggat cctgggattg ggaaatcaac
     4981 tcttctccta caagtctcaa cccagttgtc ccaagtgggg acagttctct atgtcagtgg
     5041 ggaggagtct gcccagcaga ttaaactacg tgcagagcgc ttaggtgata ttgatagtga
     5101 gttttatctc tatgcagaga ccaatatgca gagtgttcgt gcagaagtgg agcgtatcca
     5161 gccagacttt ctcattattg attccatcca gaccatcatg tctcctgaga tttcaggggt
     5221 gcaggggtct gtttctcagg tgcgtgaagt gaccgctgaa ctcatgcagt tggccaagac
     5281 caataacatt gccatcttta tcgtaggtca tgtgaccaaa gaaggaacct tggctgggcc
     5341 tcgtatgttg gagcatatgg tggatacggt gctttacttt gaaggggagc gtcaccacac
     5401 ctttcgtatt ttgagagcgg tcaaaaatcg ttttggttcc actaatgaga ttgggatttt
     5461 tgagatgcag tcgggcggct tggttgaggt actcaatccg agtcaagttt tcctagaaga
     5521 gcgtttggat ggggcgactg gttcctccat cgttgtaacc atggaaggga cgcgtccgat
     5581 tttggcggag gttcaggctt tggtaacacc gaccatgttt ggaaatgcca agcgtactac
     5641 gacaggactt gattttaacc gtgctagctt gattatggct gttttggaaa aacgggcagg
     5701 gcttctcttg caaaatcagg atgcctatct caaatctgct ggtggtgtta aattggatga
     5761 acctgcgatt gacttggctg ttgcagttgc tattgcttcg agctacaaag acaagccaac
     5821 taatcctcag gaatgttttg tcggagaact gggcttgaca ggagagattc ggcgcgtgaa
     5881 tcgtattgag caacgcatca acgaagctgc taaactgggc tttactaaga tttatgtacc
     5941 taagaattcc ttgacaggaa tcactctgcc taaggaaatt caggtcattg gcgtgacaac
     6001 gattcaggaa gtcttgaaaa aggtctttgc ataatccgtg acaaattctc ttaaaaatga
     6061 taagatagga gaaatatttg actatcaaat tttcaaggag ggaatcgtgt cgtattttga
     6121 acagtttatg caagccaatc aggcttatgt tgccctacat gggcagttaa atctgccact
     6181 taaacctaaa accagagtag ccattgtgac ctgtatggac tcacgtttgc acgttgcgca
     6241 agctctaggt ttggcacttg gggatgctca tattttgcgg aatgcaggtg gtcgagtgac
     6301 tgaggatatg attcgttctc tagttatttc ccagcaacaa atggggacaa gagaaattgt
     6361 ggtattgcat catacagact gtggtgctca gacctttgaa aatgaacctt ttcaggagta
     6421 tttgaaggaa gaattgggtg tcgatgtgtc agaccaggac ttcttgccct tccaagatat
     6481 agaagagagt gtacgcgagg atatgcaact gcttatcgag tctcccctaa taccagacga
     6541 tgtcattatc tctggtgcca tttacaatgt tgatacagga agtatgacag tcgtagaatt
     6601 ataaatactt catttagaaa gaaagtgtat gaagaaaagc aatattttat ttatttttat
     6661 tttattgcta tgtattggtt tacagtatga aaccatctac tatacggacg gttcgaggtc
     6721 aggtgcggaa tatggactaa tgggagtttc tatctttcta gctctctttt acatgattcc
     6781 ggctctttat tttctcttcc gtattgggaa aaatgggaat tgccaaagaa ggttttgatt
     6841 ctgtctttat tgggagggat gttcctttca ggctggttgt ctagttttgc taatacttat
     6901 atccatgatt tactgggggt tcttttccca gatagtccat ttttaaatgc ctttgaaagt
     6961 gctattgcgg ctcctttggt agaagaaccc ttgaaattat tgtcacttgt ttttgttttg
     7021 gctttgattc ctgtgcgaaa attaaaatct ttgtttttac ttggaattgc ttccggtttg
     7081 ggattccaaa tgattaagga tattggttat attcgtacgg atttgccaga gggctttgac
     7141 tttactattt cgcgaatttt agagcgtatc atctcaggaa ttgcctctca ctggactttt
     7201 tcaggtctag ctgtagtagg tgtttacttg ctttacagag cctataaagg acagaaggtt
     7261 ggcaagaaac agggccttat ttttctaggt ttagccttgg gaactcactt cttgtttaac
     7321 tctccttttg tggagttgga aacagagttg cctttagcga ttccagtggt tccggctatt
     7381 gctctctatg gtttttatca tgcttattgc tttgttgaga aacacaatga gttgatgacc
     7441 tagaatattt ttcaaaagaa tgatgcaagg gtacaaatat ggtgcccttc ttttattttt
     7501 gattgaaaaa tagtgcaaaa agcgctacaa tggtagatgg aaaatcttgt gaaaagcaca
     7561 agttatacat atataccgga ggaaatcatg tctttttctg atttaaagct gtttgccctt
     7621 tcttctaata aagaattggc agaacgtgtg gcgcaggaga ttgggataga gttggggaaa
     7681 tcaagtgttc gccaattttc agatggagag attcaggtca acattgaaga atcaatccgt
     7741 gggaaacacg tctttatctt acaatcaact agttcgcctg taaatgacaa tctgcttgaa
     7801 attttgatta tggtagatgc tttgaagcgt gcgagtgcag aatctgtcaa tgttgtcatg
     7861 ccttactatg ggtatgcacg tcaggataga aaggcgagag cgcgtgagcc aatcacttca
     7921 aaacttgtcg caaatatgct tgaagtagct ggagtggatc gtttattgac catcgacttg
     7981 catgctgcgc aaattcaagg attctttgat attcctgtgg atcatttgat gggtgctcct
     8041 ctgattgcag attattttga gcgtcgtggt atggttggtt ctgactatgt ggttgtcagc
     8101 ccggaccatg gaggggtgac tcgtgctcgt aagttggcag aatttttgaa aacatctatc
     8161 gctattattg ataaacgtcg tagcgttgat aagatgaata ctagtgaagt tatgaatatc
     8221 atcggtaagg ttgaaggcaa gacttgtatc ttgattgatg atatgattga taccgctgga
     8281 acgatttgtc atgcggcaga tgctcttgcg gaagctggtg ctgttgaagt ctatgcaagc
     8341 tgtacgcacc cagttctttc tggtcctgct acggacaata tccaaaaatc agctattaag
     8401 aaattggttg ttttggatac catctatctg ccagaagagc gtttgattga taagattgag
     8461 cagatttcaa tcgctcatct cctaggggat gctatcgtac gtattcatga aaaacgacca
     8521 ctttctccac ttttcgatat tgagaaaaaa atttaatgac caagcctgag atgattctca
     8581 ggttttttcg tcttttttcc gaataaatag atagtagcgg tgaatctagt aaagctagat
     8641 ttaaaactgt gatataataa aaagagaaga aatatgactg tacgtcatca gaagtttcag
     8701 cgaccatcat ttttgaacag tgatagcact tgaatcgacg ctttctaagg agaattcttg
     8761 taggcatacc agtcgtttca agataaggaa ttttagaagg tttttgaaag tcatatttct
     8821 tcaattggtt tccgcactca gggcaagatg gggcgtcgta gtccagtttg gcgatgattt
     8881 ccttgtgtgt atccttattg atgatgttta aaatctggac attagggtct ttaatgtcta
     8941 gtaattttgt gataaaatgt aattgttcca tatgattctt tctaatgagt tgttttgtcg
     9001 cttttcatta taggtcatat gggacttttt ttctacacaa aataggctcc ataatatcca
     9061 taggggattt acccactatg gatattatgg agccatttta caacagtgcc tcaaattcag
     9121 atactgacat acctaattgc tggctggcaa cctcagaagt cagaagacct tggcgtacta
     9181 tgtctaggaa ggcaaaaagt ttcctttctg cccttccttc aactttccca cgctctagtc
     9241 cttgttcaag gccttcagcc ctagcagttt ccaaggcata gtcctgtgct aacaagactt
     9301 gttcttctcg catatgtagt tgactaaaca ttttcctgtc ctcctcggac cagctcttgt
     9361 agtccagcag ttgatttgct tgggtaatgg ctcgttgcgg ttgctgggta aagggcttgt
     9421 tgccgaaaaa ctccaaccat ggcttgcgaa ccttgtcttt gctggtttct ctgtattttt
     9481 taattccaag aatgccatct taaccagatg gttttcctgt ccattgttgg taatcgccaa
     9541 tacctcacct gttgtgtctt cgcgcatact aaagctatga aaagccaggt catctgagaa
     9601 ataattacta tccacgatag caatggcgta aacaggagcg atgtgtttgt agctctagtg
     9661 agtatcacct tctcgctgac gaattttttc aagattttga ttaacctgac tgcacaggta
     9721 agcccacaag tgattgatga aaaaattctg atgatggact tgaatctcaa taattacttg
     9781 agtaccgtta tccaactccg ccaagacgtc tatactggta taaaaatcct gcaccgagta
     9841 aggcatggag agtaatacgt gaatatcgct tccctccaaa atggtcacat tttttgctgg
     9901 caagtccagc atatcgcgaa taaattgaca agtgatttct ggattgctga atattttctt
     9961 agcaatcaaa tcattagttg ggctgatgcc cggatgtctg agaatcctcc tattcctcct
    10021 tctatagtga gttgaaataa gatgtgaata actctatcag gaaagtcaaa ttaatttata
    10081 gaaatatttt agcagtcaag gtgtactatt atagattcaa tatactatat tatagcacat
    10141 ttttaaatct aggtttacta aattctctgg ctctatctat ttattcggaa aaagtttgaa
    10201 aaatacttgc tctagctctt cccaatggta ttttttgatt ctttccttta taatgggtgt
    10261 atggataaga aaaaattatt attgattgat gggtcttctg tagcttttcg ggcgtttttt
    10321 gcgctgtatc agcagttgga ccgttttaag aatgtggctg gtttgcatac caatgcgatt
    10381 tatggttttc agttgatgtt gagtcattta ttggagcggg ttgagccgag tcatattttg
    10441 gtggcttttg atgcgggaaa gacgaccttc cggacagaga tgtatgcgga ctataagggt
    10501 ggtcgggcca agactcctga tgagtttcgt gagcaatttc ctttcattcg tgagttgctg
    10561 gatcatatgg ggattcgtca ctatgatctg gctcagtatg aggcggatga catcattggg
    10621 acgctggata agctagcaga gcaggatggt tttgatatta ctattgtcag tggggacaag
    10681 gatttgattc agctgacgga tgagcatacg gtggttgaaa tttccaagaa aggtgtggct
    10741 gagtttgagg cctttacgcc agattacctc atggaagaaa tgggcctcac accagctcag
    10801 tttatcgatc tcaaggcgct catgggtgat aagtcggata atatccctgg ggtgaccaaa
    10861 gtcggtgaaa agacgggtat taagctcttg ctggagcatg gttcgcttga ggggatttat
    10921 gaaaatattg atggaatgaa gacttctaag atgaaggaaa atctcatcaa tgacaaggaa
    10981 caggcctttt tgtctaaaac actagcgacc attgatacca aggcaccgat tgcgattggt
    11041 ttagaggact tggtctatag tggtccagat gttgaaaatc ttgggaaatt ctacgatgag
    11101 atgggcttca aacagctaaa gcaggcttta aatgtgtcgt cagctgatgt gtctgagagt
    11161 ttggatttta ctattgttga ccaaatcagt caagatatgc tgagtgaaga gtctatcttc
    11221 cactttgagc tttttggtga gaattaccat acggataatt tggttggatt tgtctggtct
    11281 tgtggggata agctctatgc cacagacaag cttgagctgt tgcaagaccc gattttcaag
    11341 gatttcttag aaaaaacatc tctgagagtt tatgacttta agaaggttaa agttcttttg
    11401 caacgttttg gtgtggattt gcaggcgcct gcttttgaca tccgtttggc taaatacctc
    11461 ctttcgactg tggaggacaa tgaaattgcg accatcgcta gtctttatgg tcagacttac
    11521 ttggttgatg atgaaacttt ctacggtaag ggtgttaaaa aggccattcc tgaacgtgag
    11581 aaattcttgg aacacttagc ttgtaaactt gctgttttgg tagaaacaga gcctatttta
    11641 cttgaaaaac tcagcgaaaa tgggcaatta gagcttcttt atgatatgga gcaacctctg
    11701 gcttttgtcc ttgccaagat ggaaattgct gggattatgg tcaagaaaga gaccttgctt
    11761 gagatgcagg ctgaaaatga gcttgtcatt gaaaaactga ctcaagagat ttacgagctg
    11821 gctggtgagg agtttaatgt caactcgcct aagcagttgg gcgtgcttct ctttgagaaa
    11881 ttgggacttc ctctagaata cactaagaaa accaagacag gttattcgac agcagtggat
    11941 gttttagagc gtctcgctcc tattgctccg attgttaaga aaatcctgga ttaccgtcaa
    12001 attgctaaga ttcaatctac ttatgtaatt ggcttgcagg actggatttt ggctgatgga
    12061 aagattcata ctcgctatgt gcaggatttg acccagaccg ggcgtttgtc tagtgtggat
    12121 ccaaacttgc aaaatattcc tgcccgattg gaacaggggc gcttgattcg gaaggctttt
    12181 gtgccagagt gggaggatag tgtgctactc agctctgact attcacagat tgaattgcgc
    12241 gttttggcgc atatttctaa ggatgagcac ttgattaagg ccttccaaga gggggcagat
    12301 atccatactt cgacagccat gcgggtcttt ggcattgagc gtcctgatga tgtgactgca
    12361 aacgaccgtc gcaatgccaa ggcagttaac tttggagtgg tttatgggat ttcagacttt
    12421 ggcttgtcta ataatttggg aattagtcgt aaggaagcca aagcctacat tgatacctac
    12481 tttgaacgtt ttccaggtat taaaaactac atggatgaag tggtgcggga ggcgcgtgat
    12541 aagggctatg tagagaccct ctttaagcgt cgccgtgagt tgccagatat caattcgcgc
    12601 aacttcaata ttcgtggttt tgcggagcga actgctatca actcacctat ccagggttcg
    12661 gcagcagata ttctcaagat tgccatgatt cagctggata aagccttggt tgcaggtggt
    12721 tatcagacta agatgctgtt acaagtgcac gatgaaatcg tccttgaagt gcctaaatct
    12781 gaattggtag agatgaaaaa attggtgaaa caaaccatgg aagaagccat tcaactcagt
    12841 gttcctctta tcgcagatga gaatgaaggg gcaacctggt acgaggctaa ataaaaaggg
    12901 ggctagtcct ccttttttgt agtataattc tgcaaacctt ttcaaaatgt gctatactga
    12961 tgaaaaagga ggatttctat gagtcaagaa tttatcaatc caagtgatgg cgtgattcgt
    13021 cagtatctcg caacgagtaa aacccttgct gtggtgggtt tgtctgaccg tgaagaaaca
    13081 accagcaatc gagtaacaaa ggaaatgcag gctcggggct ataaaatcat cccagtcaat
    13141 cccaaggcgg caggtggcga aatcttgggt gaaaaggctt atgctagcct cgctgaaatt
    13201 ccttttcctg tagatattgt caatgtttat cgtcgcagtg aatttctgcc cgatgtggcg
    13261 cgtgattttc tcaaagctga tgccaagatt ttttgggcac agctaggact tgaaagttta
    13321 gaagcgaaag agattttgcg tgatggtgga tgtgatgata tcgtgatgaa tcgctgtatc
    13381 aagagagaac atactcgctt gattgaggaa gcataagaaa aaggtagctg atgggctacc
    13441 ttttgtgtta tactcaatga aaatcaaaga gcaaactagg aaactagcca cgggctgctc
    13501 aaaacactgt tttgaggttg cagatagaac tgacgaagtc agctcaaaac actgttttga
    13561 ggttgtagat acgactgacg aagtcagctc aaaacaccgt tttgaggttg cagatagaac
    13621 tgacgaagtc agctcaaaca ccgttttgag gttgcagata gaactgacga agtcagtaac
    13681 atatacctac ggcaaggcga cgttgacgtg gtttgaagag attttcgaag agtattagaa
    13741 aatgccgata agggtctgca taccaagagt ggtgaggatg atggcaatcc agcagatggc
    13801 tccaagaaga atggattttc cactggattt gaccatagcg accagattgg ttttgagacc
    13861 gatagcactc atggccatga caataaggaa tttagagagt tctttgagag gagtaaagaa
    13921 actactggac acacctagag aggtgagtag tgtagtgagg agagaggcaa ggataaagta
    13981 aaggataaaa agtgggaaga cttttttcag ttgcaggctt tgcttgtttt cttgttggcg
    14041 actttgccag taggatagaa agagcgtgat agggataatg gccaaagtac gtgtgagttt
    14101 aacaatggtt gcagactcga gggtattgct ttggtaaaga ctgtcccaag cgctggcggc
    14161 agccgttaca gaggaagtgt cgttgaccgc agtccctgca aagagggcga agccttcatt
    14221 ggatagatga agccaggtgc cgagggttgg aaagatgagc gcagccaaga cattgaagaa
    14281 aaagataacg gaaatggctt gggctacttc cttttcctta gcatcaataa cgggcgctgt
    14341 cgctgcaatg gcagaacccc cacagataga agaacctact ccaaccaagg tagccagttt
    14401 tgtatccagg gcaaagaaac gctggaagag gtaggcaata atcagagcta ttgagatagt
    14461 ggacaggatg acagggagtg aagattggcc aactgcgaag acctgcgaga tattgagacc
    14521 aaaaccaagc aagacaacgg catattggag caacttcttg gaactaaagg tcaaaccagc
    14581 atccagttgt ttataggacg agagaaaggg atgtaggagc atgcctatga aaatggcaaa
    14641 aacgggcgcg ccaaccacag ggaagaatcc tcctaagtac caagatagga tggaaatgag
    14701 aaggcaggcc aagatacctg ctccattttt tgatagaaat gacataaaaa cctccaaata
    14761 aaatctatta ccattataga cctataaaca ggaaaagtaa aatagaaagt ggaaagctat
    14821 tctctaatgt atttttgcgg tcggggggct tttgtagtat aatagagata cgttttgaaa
    14881 gtaggaggta tctatggact taactaagcg ctttaataaa cagttagata aaattcaagt
    14941 ttcgttgatt cgtcagtttg accaggctat ttcggagatt cctggggtct tgcgtttgac
    15001 cttgggggaa cctgatttta caacgccaga ccatgtcaag gaggcgggca agcgagcgat
    15061 tgatcagaac caatcctact atacagggat gagtggtctg ctgactctac gtcaggcagc
    15121 cagtgacttt gttaaggaaa agtaccaact ggactatgct cctgaaaatg aaatcttggt
    15181 tacaattggg gcgacagagg ctttatctgc gactttgacg gctattttgg aagagggaga
    15241 caaggtactt ttgccagctc ctgcttatcc aggctatgaa ccgattgtta acttagttgg
    15301 ggcagaaatt gttgagattg atacgactga aaatggtttt gtcttgactc ctgagatgtt
    15361 ggagaaggcc attttggagc agggtgataa gctcaaggcg gttattctca actatccagc
    15421 caatccgaca ggaattacct acagtcgaga gcagttagag gccttggcag ctgttttacg
    15481 caagtacgaa atttttgttg tctgtgatga ggtttactca gaattgacct acacaggcga
    15541 agcccatgtg tctctaggaa cgatgttgag agaccaggct attattatca atggtttgtc
    15601 taaatcgcat gccatgacag gttggcgttt ggggctgatt ttcgctcctg cgaccttcac
    15661 agcccagtta atcaagagtc accagtactt ggtcactgcc gcaaatacca tggcgcaaca
    15721 tgctgcggta gaagccttga cggctggtaa aaacgatgcg gagcccatga agaaggaata
    15781 tatccaacgt cgggactata tcatcgaaaa aatgactgct cttggttttg agattatcaa
    15841 accagacggt gccttctata tttttgctaa aattccagcg ggctacaatc aagactcctt
    15901 tgcttttctg aaggattttg ctcagaagaa ggccgttgcc tttatccctg gtgcagcctt
    15961 tggacgttac ggggaaggct acgtccgcct atcttatgca gccagcatgg agactatcaa
    16021 agaagccatg aaacgacttg aggagtacat gagagaagca tgattcagtc tatcacgagt
    16081 caaggcttgg tgctttacaa tcgcaatttt cgtgaggatg acaagctcgt caaaattttt
    16141 acagagcagg ttggcaaacg catgtttttt gtcaaacacg ctggtcagtc taagctggcg
    16201 cctgttattc agcccttggt gctggcacga tttctcttgc gaatcaatga tgacggactc
    16261 agttacatcg aagactatca tgaggtcatg acttttccca agattaatag tgacctcttt
    16321 gtcatggcct atgcgaccta tgtggcagct cttgcagatg ctagtttgca ggacaatcag
    16381 caggatgctc ccttgtttgc ttttttgcaa aagactttgg agttgatgga agcaggcttg
    16441 gattatcagg ttttgaccaa tatttttgaa attcaaattt tgactcgatt tggaatcagc
    16501 ctcaatttta atgagtgtgt cttctgccat cgggttggtc aggcttttga cttttctttc
    16561 aaatatggag cctgcctctg tccagagcat tatcatgagg ataagagacg ttgtcatctc
    16621 aatcccaata tcccctatct gctcaatcaa tttcaagcta ttgattttga gactttggag
    16681 accatttcgc tcaagcctgg aatcaagcaa gagctacgcc aatttatgga tcaattatat
    16741 gaagagtacg ttgggattca cctaaaatca aagaaattta ttgattccct agcagactgg
    16801 ggacaattac taaaagagga aaagaaatga aaaaaatcgc agtagatgcc atggggggcg
    16861 attacgcacc tcaggccatt gttgagggtg tcaatcaagc cctatctgac ttttcagata
    16921 tcgaggttca actttacgga gatgaagcta aaatcaagca atatctgaca gcgacagagc
    16981 gcgtcagcat tatccatacg gatgagaaga ttgattcgga tgatgaacct acgagagcta
    17041 ttcggaataa gaaaaatgcc agtatggtat tggcagccaa ggctgtcaaa gatggtgaag
    17101 cagacgctgt cctttcggct gggaatacag gtgccttgtt ggcagcagga ttcttcatcg
    17161 tgggtcgtat caagaatatc gaccgtcctg gactcatgtc taccttgcct accgttgatg
    17221 gaaaaggttt tgacatgcta gaccttggtg ccaatgcaga aaatacagcc cagcacctcc
    17281 atcaatatgc ggttctaggt tccttctatg ctaaaaatgt ccgtggcatt gcgcaaccac
    17341 gcgttggttt gctcaacaac ggaacagaga gtagcaaggg cgacccgctt cgtaaggaaa
    17401 cttatgaatt actggcggct gatgaaagtt tgaactttat cggaaacgtg gaagcgcgtg
    17461 atttgatgaa tggcgttgca gatgttgttg tggcagatgg tttcacggga aacgctgtgc
    17521 tcaaatccat cgaagggaca gctatgggaa tcatgggctt gctcaagaca gctattacag
    17581 gtggtggtct tcgagcgaaa ctaggtgccc tccttctcaa ggacagcctc agtggtttga
    17641 aaaaacagct caattattca gatgttggtg gagcggtctt gtttggtgtt aaggcacctg
    17701 ttgtcaagac tcatggctca agcgatgcca aggctgttta tagtacgatt cgtcagatcc
    17761 gtaccatgct agaaacagac gtggttgccc agactgcgcg tgaattttca ggagaataaa
    17821 agagatgaca gaaaaagaaa tttttgaccg tattgtgacc attatccaag agcgacaggg
    17881 agaggacttt gtcgtgacag aatccttgag tctgaaagac gatttggatg cggattctgt
    17941 tgacttgatg gagtttatct tgactctgga agatgaattt agtatcgaaa tcagcgatga
    18001 agaaattgac caactccaaa acgtaggaga tgtggttaaa atcattcaag gaaaatagca
    18061 atcggagttc caagtcaacg gaagtagatg gtttttagaa atgagaaata tcggacaagc
    18121 tggtaaaatc ttggctgaca gtggttatca agggctcatg aagatatatc ctcaagcaca
    18181 aactccacgt aaatccagca aactcaagcc gctaacagtt gaagataaag cctgtaatca
    18241 tgcgctatct aaggagataa gcaaggttga gaatatcttt gccaaagtaa aaacgtttaa
    18301 aatgttttca acaacctatc gaaatcatcg taaacgcttc ggattacgaa tgaatttgat
    18361 tgctggtatt atcaatcatg aactaggatt ctagttttgc aggaagtcta atagtaaaaa
    18421 agtgattaga aaacatcttt tttaaaaata gagatgattt tgaaacaaaa aagctaattc
    18481 aagacgtttc gatgccaatt caagatttgg atgaaaaaaa ttaatagata ctgttatact
    18541 aaacttgtca agtttgtaac aagacaaata ttaaaaataa aaaagaggta ttcgttatga
    18601 atacaaaaac gatgtcacaa tttgaaatta tggatactga gatgcttgct tgcgttgaag
    18661 gtggcggatg caattgggga gattttgcca aagcaggtgt tggaggagga gcagcacgag
    18721 gtcttcagct aggaattaaa acaagaacat ggcaaggtgc agcaactggt gctgtgggag
    18781 gagctatact tggaggtgtg gcctatgcag cgacatgttg gtggtaatta tggattttaa
    18841 aagttttatt attggtttag tagttggtat atttggtcct tatatggatg atttaattag
    18901 aaaaaaattt ttaaagtctt cggagaagaa aacagaaaaa tctgttaaaa aataatcaaa
    18961 actataaatg atgaatctga atcaaaatta ttttgcgcat gtaaagagga gtcttatagt
    19021 aacgagtcaa aaaaggagta actatgaatc gtaatttaga acggtgttat ctattctgac
    19081 taggaataga tcataccaga ggtagcttag aaatagcaga gacattagaa attgaagtaa
    19141 taaataggat gtcgtaagtg ttactatcaa tgatttattt gtttcaagct tgcctagggt
    19201 gacagtaaaa aatcaatttc ctttcaatag catattttta gtgggcagga ctcttgttct
    19261 gcctattttt ttatccaaaa agtgcagttg ggagggagat aggctcattt gggaaggaag
    19321 tccagttttt gtttagtgat tggggtaaga tagttgttat cagatgagtt aatactcttc
    19381 gaaaatcaaa ttcaaaccac gtcaacgtcg ccttgccgta tatatgtgac tgacttcgtc
    19441 agtcctatct acaacctcaa aacagtgttt tgagcagcct acggctagtt tcctagtttg
    19501 ctctttgatt ttcattgagt attagggaaa aggagatgaa tatgaaattt gggaaacgtc
    19561 attatcgtcc gcaggtggat cagatggact gcggtgtagc ttcattagcc atggtttttg
    19621 gctactatgg tagttattat tttttggctc acttgcgaga attggctaag acgaccatgg
    19681 atgggacgac ggctttgggc ttggtcaagg tggcagagga gattggtttt gagacgcgag
    19741 ccattaaggc agatatgacg ctttttgact tgccggattt aacttttcct tttgttgccc
    19801 atgtgcttaa ggaagggaaa ttgctccact actatgtggt gactgggcag gataaggata
    19861 gcattcatat tgccgatcca gatcccgggg tgaagttgac taaactgcca cgtgagcgtt
    19921 ttgaggaaga atggacagga gtgactcttt ttatggcacc tagtccagac tataagcctc
    19981 ataaggaaca aaaaaatggt ctgctctctt ttatccctat attagtgaag cagcgtggct
    20041 tgattgccaa tatcgttttg gcaacactct tggtaaccgt gattaacatt gtgggttctt
    20101 attatctgca gtctatcatt gatacctatg tgccagatca gatgcgttcg acactaggga
    20161 ttatttctat tgggctagtc atcgtctaca tcttccagca aatcttgtct tacgctcagg
    20221 agtatctctt gcttgttttg gggcaacgct tgtcgattga cgtgattttg tcctatatca
    20281 agcatgtttt tcacctccct atgtccttct ttgcgacacg caggacaggg gagatcgtgt
    20341 ctcgttttac agatgctaac agtatcatcg atgcgctggc ttcgaccatc ctttcgattt
    20401 tcctagatgt gtcaacggtt gtcattattt cccttgttct attttcacaa aataccaatc
    20461 tctttttcat gactttattg gcgcttccta tctacacagt gattatcttt gcctttatga
    20521 agccgtttga aaagatgaat cgggatacca tggaagccaa tgcggttctg tcttcttcta
    20581 tcattgagga catcaacggt attgagacta tcaagtcctt gaccagtgaa agtcagcgtt
    20641 accaaaaaat tgacaaggaa tttgtggatt atctgaagaa atcctttacc tatagtcgag
    20701 cagagagtca gcaaaaggct ctgaaaaagg ttgcccatct cttgcttaat gtcggcattc
    20761 tctggatggg ggctgttctg gtcatggatg gcaagatgag tttggggcag ttgattacct
    20821 ataatacctt gctggtttac tttactaatc ctttggaaaa tatcatcaat ctgcaaacca
    20881 agcttcagac agcgcaggtt gccaataacc gtctaaatga agtgtatcta gtagcttctg
    20941 agtttgagga gaagaaaaca gttgaggatt tgagcttgat gaagggagat atgaccttca
    21001 agcaggttca ttacaagtat ggctatggtc gagatgtctt atcggatatc aatttaaccg
    21061 ttccccaagg gtctaaggtg gcttttgtgg ggatttcagg gtcaggtaag acgactttgg
    21121 ccaagatgat ggttaatttt tacgacccaa gtcaagggga gattagtctg ggtagtgtca
    21181 atctcaatca gattgataaa aaagccctgc gccagtacat caactatctg tctcaacagc
    21241 cctatgtctt taacggaacg attttggaga atcttctttt gggagccaag gaggggacga
    21301 cacaggaaga tatcttacgg gcggtcgaat tggcagagat tcgagaggat atcgagcgca
    21361 tgccactgaa ttaccagaca gaattgactt cggatggggc agggatttca ggtggtcaac
    21421 gtcagagaat cgctttggcg cgtgctctct tgacagatgc gccggtcttg attttggatg
    21481 aggcgactag cagtttggat attttgacag agaagcggat tgtcgataat ctcattgctt
    21541 tggacaagac cttgattttc attgctcacc gcttgactat tgctgagcgg acagagaagg
    21601 tagttgtctt ggatcagggc aagattgtcg aagaaggaaa gcatgctgat ttgcttgcac
    21661 agggtggctt ttacgcccat ttggtcaata gctagaaaga ggagaggatg aaaccagaat
    21721 ttttagaaag tgcggagttt tataatcgtc gttaccataa tttttccagt agtgtgattg
    21781 tacccatggc ccttctgctt gtgtttttac ttggctttgc aactgttgca gagaaggaga
    21841 tgagtttgtc cactagagct actgtcgaac ctagtcgtat ccttgcaaat atccagtcaa
    21901 ctagcaacaa tcgtattctt gtcaatcatt tggaagaaaa taagctggtt aagaaggggg
    21961 atcttttggt tcaataccaa gaaggggcag agggtgtcca agcggagtcc tatgccagtc
    22021 agttggacat gctaaaggat caaaaaaagc aattggagta tctgcaaaag agcctgcaag
    22081 aaggggagaa ccactttcca gaggaggata agtttggcta ccaagccacc tttcgcgact
    22141 acatcagtca agcaggcagt cttagggcta gtacatcgca acaaaatgag accatcgcgt
    22201 cccagaatgc agcagctagc caaacccaag ccgaaatcgg caacctcatc agtcaaacag
    22261 aggctaaaat tcgcgattac cagacagcta agtcagctat tgaaacaggt gcttccttgg
    22321 ccggtcagaa tctagcctac tctctttacc agtcctacaa gtctcagggc gaggaaaatc
    22381 cccaaactaa ggttcaggca gttgcacagg ttgaagcaca gatttctcag ttagaatcta
    22441 gtcttgctac ttaccgtgtc cagtatgcag gttcaggtac ccagcaagcc tatgcgtcag
    22501 ggttaagcag tcaattggaa tcccttaaat cccaacactt ggcaaaggtt ggtcaggaat
    22561 tgacccttct agcccagaaa attttggagg cagagtcagg taagaaggta cagggaaatc
    22621 ttttagacaa ggggaaagtt acggcgagtg aggatggggt gcttcatctt aatcctgaga
    22681 ccagtgattc tagcatggtt gcagaaggtg ccctactagc ccaactttat ccatctttgg
    22741 aaagagaagg gaaagccaaa ctcacagctt atctaagttc aaaatatgta gcaagaatca
    22801 aggtcggtga ttctgttcgc tatactacga ctcatgatgc cgggaatcaa cttttcctag
    22861 attctactat tacaagtatt gatgcgacag ctactaagac tgagaaaggg aatttcttta
    22921 aaatcgaggc ggagactaat ctaacttcgg agcaggctga aaaacttagg tacggggtgg
    22981 aaggccgctt gcagatgatt acgggcaaga aaagttacct acgttattat ttggatcaat
    23041 ttttgaacaa agagtaatgt tcgtgttttt agagttaaat aatttttaaa ctgtgagaaa
    23101 gattcttctt gcagtttttt ctttacaatt tttgaaaaac atctactatt tattcggtta
    23161 aattcttgtg ttttttggtt ttttgtggta aaatgtgctc aagtaatacg aaaggcgaac
    23221 tttaaaatgt caaaacaatt gatctattcg ggaaaagcta aagatatcta tacaactgag
    23281 gatgaaaatc ttattatttc aacttacaag gaccaggcga ctgctttcaa cggtgtcaag
    23341 aaggagcaga ttgcaggtaa gggagtcttg aataatcaga tctcatcttt tatttttgag
    23401 aaattaaatg tggctggtgt ggcgactcac tttgtggaga aactttcaga cacggaacaa
    23461 ctcaataaaa aggttaagat tattcctttg gaagtcgtgc tccgcaacta tactgctggt
    23521 tccttttcaa aacgttttgg tgtggatgag ggaatcgcct tggagactcc gattgtcgaa
    23581 ttttactaca aaaatgatga tttggatgat ccatttatca atgatgagca tgtgaaattc
    23641 ctacagattg cgggtgacca gcagattgcc tacttgaagg aagaaacgcg tcgtatcaat
    23701 gaactattga aagtctggtt tgctgagatt gggcttaaat tgattgactt taagctagag
    23761 ttcggttttg acaaggatgg caagattatc ttggcagacg aattttcacc agataactgc
    23821 cgcttgtggg acgctgatgg caaccacatg gataaggatg ttttccgtag aggattggga
    23881 gaactaaccg acgtttatga gattgtttgg gaaaagttgc aggaattgaa ataatctgtt
    23941 tgcaacggaa aaccttcgtc tctcaactaa aaggactcag gctgaaaagg tcccccagac
    24001 cttttcactc tgtagagaac taggtgaact aacagatgtt tacgaaattg tctgggaaaa
    24061 gttgcagggt ttaaaataac aacctcaagg ctgtttggga atattgcaag agctgaaata
    24121 aaggaataag aattgatgga taaacgtatt tttgttgaaa aaaaggctga ttttcaggtc
    24181 aagtcagaga gtttggttag agagctccag cacaacttgg gactgtcaag cttgaaaagt
    24241 attcgtattg tgcaagtata tgatgtattt gacttggctg aggacttgtt tgcacctgca
    24301 gagaagcaca ttttctctga gcaggtaacc gaccatgttt tagatgaagt atctgtgcag
    24361 gcggatcttg ctaactatgc tttctttgcc attgaaagtc tgccagggca gtttgaccag
    24421 cgtgcagctt cgtcacagga agccttgctt ttgttgggaa gttcgagtga cgtgacagtc
    24481 aacacagccc aactttactt ggtgaataaa gatattgatg cgactgagtt ggaagctgtc
    24541 aaaaactacc tgctcaatcc agttgattct cgtttcaagg atatcacgac agggattgcc
    24601 aagcaggagt tttcagagtc agacaagacc attcccaaat tgactttctt tgaaagctat
    24661 gcagcagaag actttgctcg ctacaaggcc gaacaaggga tggccatgga agtggatgat
    24721 ttgctcttta tccaagacta ctttaagtca atcgggcgcg tgccaactga gactgaactc
    24781 aaggttttgg acacttactg gtctgaccac tgccgtcata cgacttttga gacagagttg
    24841 aaacacatcg acttttcagc ttctaaattt caaaagcaat tgcagtcaac ctatgacaag
    24901 tatattgcca tgcgcgagga attaggtcgg tctgaaaaac cacaaacctt gatggatatg
    24961 gcgactattt tcggtcgtta tgagcgtgct aatggacgat tggatgatat ggaagtctct
    25021 gacgaaatca atgcctgctc agttgaaatt gaagtggacg ttgatggtgt caaggaacct
    25081 tggctcctca tgtttaaaaa cgaaacccac aaccatccaa cagaaattga gccatttggt
    25141 ggagcggcta cctgtattgg tggagctatt cgtgatccgt tgtcaggccg ttcctatgtt
    25201 taccaagcca tgcgtatttc aggtgctggt gatattacag caccgatttc ggaaactcgc
    25261 gctgggaaat tgccacaaca agtcatttct aaaacagcag ctcatggtta ttcttcatat
    25321 ggtaaccaga ttgggcttgc aacaacctac gttcgtgaat acttccaccc aggctttgta
    25381 gctaaacgta tggaacttgg tgccgttgtt ggtgcgactc ccaagggcaa tgttgtccgt
    25441 gaaaaacctg aagcaggtga tgtgatcatc cttctcggag gcaaaacagg tcgtgatggt
    25501 gtcggtggtg cgacgggctc ttctaaggtt caaacagttg agtctgtaga gactgctggt
    25561 gctgaggttc aaaaaggaaa tgccatcgaa gaacgcaaga ttcagcgcct cttccgtaat
    25621 ggcaatgtca ctcgtctgat caagaagtcc aatgactttg gggcaggcgg tgtctgtgtg
    25681 gctatcggtg aattggcaga cggtcttgaa atcgacctca acaaggtgcc tcttaaatac
    25741 cagggcttga atggtacaga aattgccatc tctgaatcac aagaacggat ggcggtcgtg
    25801 gttcgtcctg aagatgtgga tgccttcgtt gccgaatgta acaaagaaaa tattgatgct
    25861 gttgtggtgg cgacagtaac tgaaaaacca aatcttgtca tgcactggaa tggtgagaca
    25921 atcgttgact tggagcgtcg tttccttgac accaatggtg tgcgcgtggt tgtcgatgcc
    25981 aaagttgtgg acaaggatgt caaactccca gaagagcgtc aaacatctgc tgaaacactg
    26041 gaatcagata cccttacggt tctatctgac ctcaaccatg caagtcaaaa aggattacag
    26101 actatctttg actgctctgt tggacgctca acggttaatc acccacttgg tggtcgttac
    26161 caactcacac caactgaggc atctgtgcag aaattgccag ttcaacacgg tgtgactcat
    26221 actgcgtcgg tcattgctca aggtttcaac ccatatgtag ctgaatggtc tccataccac
    26281 ggtgctgctt atgcggttat cgaagcaact gctcgtttgg tggctgctgg tgccaactgg
    26341 ttcaaggctc gtttctctta ccaagagtat ttcgagcgta tggataaaca agcagagcgt
    26401 ttcggtcagc cagtagctgc tcttctaggt tctattgaag cacaaattca gcttggcttg
    26461 ccatctatcg gtggtaagga ctccatgtct ggtacctttg aagaattgag cgttccgcca
    26521 accttggctg cctttggggt gacgacggca gatagccgta aggtgctctc tccagaattt
    26581 aaagctgttg gggaaaatat ctactacatc ccaggtcaag ccctctctgc agagattgat
    26641 tttgacttga ttaagaaaaa ttttgctcag tttgaagcca tccaagctga ccataaagtg
    26701 acatctgcat cagctgtcaa atacggtggt gtagttgaaa gtttggctct tgctaccttt
    26761 ggaaactata ttggtgcaga ggtgaccttg cctgaacttg aaacagcttt gacagctcaa
    26821 ttaggcggct ttgtcttcac atctcctgaa gaaattgctg gagtagagaa ggttggacaa
    26881 acgaaagcag actttacact gactgtcaac ggtgtgaagc tagatggaca caagcttgac
    26941 agtgcatttc aagggacatt ggaagaagtt tacccaacag aatttaccca agcgaaagaa
    27001 ctagaagaag taccagctgt ggcatcagat gttgtgatta aagccaaaga aaaggttgaa
    27061 aaacctgtgg tttacatccc agtctttcca ggaaccaact cagaatatga ttcagctaag
    27121 gccttcgaaa aagaaggtgc agaggtcaat ttggtgccat tcgtgacctt gaatgaagaa
    27181 gctattgtca agtcagttga aactatggtt gacaatatcg acaagactaa tattctcttc
    27241 tttgctggtg gattctcggc tgcggatgaa ccagatggtt cagctaagtt tatcgtcaat
    27301 atcctgctta atgaaaaagt gcgtgtggct attgatagct ttatcgcccg tggtggtttg
    27361 attatcggta tttgtaatgg attccaagcc ttagtcaaat cgggtctcct accctacgga
    27421 aactttgaag ctgctaacag tactagccca accctcttct acaatgatgc caaccaacac
    27481 gtggccaaga tggtggaaac tcgcattgcc aataccaact caccatggtt ggttggtgtg
    27541 caagtgggcg atatccacgc tattcctgtt tcgcacggtg aagggaagtt tgtcgtgacg
    27601 gctgaggaat ttgcagagct ccgtgacaat ggacaaattt tcagccaata cgttgacttt
    27661 aacggtaaac caagtatgga ttctaagtac aatccgaatg gttctgtcca tgccatcgaa
    27721 ggaattacca gcaagaatgg tcaaatcatc ggtaagatgg gccactcaga acgttatgag
    27781 gatggtcttt tccaaaatat cccaggcaat aaagaccaac acctgttcgc atcagcggtt
    27841 aaacatttca ctggaaaata agacttacag attttctaat agatagtatc agtaatgtaa
    27901 aagtcatgta aatctagctc ttgatgatta caaatgaaaa ttaggtataa aaaatgacat
    27961 acgaagtaaa atctcttaat gaagaatgtg gtgttttcgg tatttgggga catccagatg
    28021 ctgctaagtt gacctatttt ggactccaca gtcttcaaca ccgtggtcag gagggggcag
    28081 gaatcctctc caatgatcaa ggacaactga agcgccatcg tgacatgggg cttttatcag
    28141 aagttttcag aaatccagct aatttggata aattgacagg agctggtgcg attgggcatg
    28201 tgcgttatgc gactgctggc gaagcttctg tagataacat ccagcccttc ctcttccgtt
    28261 ttcacgatat gcagtttggt ttggctcata atggaaatct gaccaatgca gcctctctca
    28321 agaaagaact ggaacaaaga ggagcaattt tcagcgcgac ttcggactct gaaatcttgg
    28381 ctcacctcat tcgtcgcagt cataatccta gcctgatggg caaaatcaag gaagcgctca
    28441 gccttgtcaa aggtggtttt gcctatatct tgctgtttga ggacaagttg attgcggctc
    28501 ttgacccaaa tggattccga ccgctttcga ttggtaaaat ggctaatgga gcagttgttg
    28561 tatcttctga aacctgtgct tttgaggtca ttggtgccga gtggattcgt gatttgaagc
    28621 caggtgagat tgtgatcatt gatgacgagg gcattcagta tgacagctat acagatgata
    28681 cccagttggc ggtttgttct atggagtata tctactttgc tcgccctgat tctaatatcc
    28741 acggtgtcaa tgtccatacg gcacgtaaga gaatgggagc gcaattggcg cgagaattta
    28801 agcatgaggc agatattgta gttggtgtgc ccaattcttc cctaagcgcg gctatgggat
    28861 ttgcggaaga atcaggctta ccaaatgaaa tgggtctgat caaaaaccaa tacacccagc
    28921 gaacttttat ccaaccgact caagaattgc gggagcaagg agtgcggatg aaactgtctg
    28981 ctgtttcggg tgttgtcaaa ggcaaacgtg tggtcatggt ggatgattcc attgtacgtg
    29041 gaacaacctc tcgtcgtatc gttcagctct tgaaagaagc gggtgcgact gaggttcacg
    29101 ttgccattgg aagtcctgca ctagcgtatc catgtttcta cgggattgat atccagaccc
    29161 gtcaggagct gattgcagcc aatcatacgg tcgaagaaac tcgccaaatc attggtgcgg
    29221 acagtctgac ttatctttca attgatggct tgattgagtc gattggtatc gaaacagatg
    29281 cgccgaacgg tggtctctgt gtcgcttact ttgacggtga ctacccaacg cctctttatg
    29341 actacgaaga agactatcgt agaagtttgg aagaaaagac cagtttttac aagtaggcga
    29401 cagattctcc attaaagaaa aggaaaaaat aaatgacaaa taaaaatgca tatgcctcac
    29461 gtctcactac tgactaaagg cttaagcatt tagtcagtag acgctttgtc ctataggatc
    29521 aaagctagag ccctgactag tatttttaga taaaaagatg gtttatctaa aaatacgtcg
    29581 cagtctttct caaaaaaaga aaaggaaaaa taaaatggca aataaaaatg cgtacgctca
    29641 atctggtgtg gatgttgaag cgggttatga agttgttgaa cggattaaaa agcacgtggc
    29701 ccgtacggag cgtgcaggtg tcatgggagc tcttggtggc tttggtggta tgtttgacct
    29761 ttccaagact ggggttaaag aacccgtctt gatttcaggg actgacggtg tcggaaccaa
    29821 gctcatgttg gctatcaagt acgacaagca cgataccatc gggcaggact gtgtggccat
    29881 gtgtgtcaac gacatcattg ctgcaggtgc ggaacccctc tattttctcg actacgtagc
    29941 gacagggaag aatgaaccag ctaagctaga acaagtggtt gctggtgtgg cagaaggttg
    30001 tgtgcaggct ggtgctgccc tcatcggtgg ggaaacggct gaaatgccgg gcatgtacgg
    30061 cgaagacgac tatgacttgg ctggttttgc ggtcggtgtg gctgaaaaat ctcaaatcat
    30121 tgacggttca aaggtggtag agggagatgt tcttctcgga cttgcttcaa gtgggattca
    30181 ctcaaatggt tactctttgg ttcgtcgtgt ctttgcggat tacacaggtg aggaagtcct
    30241 accagaattg gaaggcaaga aacttaagga agttctactt gagccgactc gtatctatgt
    30301 caaggctgtc ttgccgctca tcaaagaaga gttggtcaac ggcattgccc acatcacagg
    30361 tggtggcttt atcgaaaatg tccctcgtat gtttgcagat gacctagctg ctgaaattga
    30421 tgaaagtaaa gttccagtgc ttccaatttt caaaaccctt gaaaaatacg gtcagattaa
    30481 acacgaagaa atgtttgaaa tcttcaatat gggtgtggga cttatgttgg cggtcagccc
    30541 tgaaaatgta gagcgtgtaa aagaattgtt ggatgaagca gtctatgaaa ttggtcgcat
    30601 cgtcaagaaa gaaaacgaaa gtgtcattat caaatgaaaa aaatagcggt ttttgcctct
    30661 ggtaatggct caaattttca ggtgattgcc gaagaatttc cagtggagtt tgtcttttca
    30721 gaccatcgtg atgcctatgt gcttgagcgt gcaaagcagc tcggcgttct gtcctatgct
    30781 tttgaactca aggagtttga gagcaaggca gactacgaag cagcccttgt cgaactcttg
    30841 gaagaacacc agattgactt ggtttgccta gcaggctaca tgaaaatcgt tggaccaacc
    30901 ttattgtcgg cttatgaagg tcggattgtc aacattcatc cagcctactt gccagaattt
    30961 ccaggagctc atgggattga ggatgcttgg aatgctggcg tgggtcagtc tggtgtgacc
    31021 attcactggg tggattcggg tgtggataca ggccaggtca tcaaacaggt tcgtgtgcca
    31081 cgactagctg atgataccat tgacagattt gaagctcgca tccatgaagc agagtacagg
    31141 ctgtatccgg aagtagtgaa ggctctattt acagattgac tttttgatga ttcatatgat
    31201 atctttgatt ttaaattgga gtcagtgttt gttgaagacg gcttcaaacg gaggtatttg
    31261 taatgttaga atctaaaaaa acaactcgat atgtatttta tgtctatctg atgttattaa
    31321 cttggggaat cttatttaag tttgaaacaa atcctgaatt tatagcattt ttcttagctc
    31381 caaggtatat caattggatt ccattttcag aaccactaat agtcgatgga aaaattgttt
    31441 ttgctgaaat gttatttaat ctgattttct ttattccatt aggtgtttgt ttccctttga
    31501 taaaaactaa tttatctagt ttaagaatag tcgggacagg tttcttgatt agtttattgt
    31561 ttgagtgctt acagtatatt ttagcaatag gtataacaga tataacggat ttgactttaa
    31621 atacgctagg tgtctgtgta ggcttactga tttatcaaat ttttataaga gtgttcaaat
    31681 cacagactag aaaatggatc aatatcttag gtatgcttag ccttggtttt gcttatcttg
    31741 ttttactgtt actgcattta cttagtgttt aactaatgat taaaaaggag aatataatga
    31801 ctaaacgcgt cttaatcagc gtctcagaca aagcgggcat tgttgaattt gcccaagaac
    31861 tcaaaaaact tggttgggag attatctcaa caggtggaac taaggttgcc cttgataatg
    31921 ctggggtgga taccattgct atcgatgatg tgactggttt cccagaaatg atggacggtc
    31981 gtgtgaagac cctccaccca aatatccacg gagggcttct cgctcgtcgt gacttggata
    32041 gccacttgga agcggctaag gacaacaaga ttgagctcat tgaccttgtg gtggtcaacc
    32101 tttacccatt taaggaaact atccttaaac cagatgtgac ttatgctgat gcagttgaaa
    32161 atatcgatat tggtgggcca tctatgcttc gttcagcagc gaaaaatcat gccagtgtta
    32221 cagttgtggt agatcctgct gactacgctg tggttttgga tgaattggca gcaaacggcg
    32281 aaacctctta tgaaactcgc caacgtttag cagccaaagt atttcgtcac acagcggctt
    32341 atgacgcctt gattgcagaa tacttcacag ctcaagtggg tgaaagcaag cctgaaaaac
    32401 tcactttgac ttatgacctc aagcaaccaa tgcgttacgg tgagaatcct caacaagacg
    32461 cggactttta ccagaaagct ttgcctacag actactccat tgcttcagcc aaacagctca
    32521 acgggaaaga attgtcattt aataatatcc gtgatgcaga tgctgctatc cgtatcatcc
    32581 gtgacttcaa agatagtcca accgttgtgg ctctcaaaca catgaatcca tgtggaattg
    32641 gtcaagctga tgacatcgag actgcttggg actacgctta tgagtctgac ccagtgtcta
    32701 tctttggtgg gattgtcgtc ctcaaccgtg aggtggatgc tgcgacagct gagaagatgc
    32761 acggcgtttt cctcgaaatc atcattgcac caagctatac ggatgaagcg ctagccattt
    32821 tgatcaataa aaagaaaaac ttgcgtatcc ttgccttgcc atttaatgct caagaggcta
    32881 gcgaagtgga agcagaatac acaggtgtag tcggtggact tctcgtgcaa aatcaagacg
    32941 tggtcaagga aagcccagct gactggcaag tggtgactaa acgtcagcca actgagacag
    33001 aagcgactgc tcttgagttc gcttggaagg ctatcaagta cgtcaaatca aatggtatta
    33061 tcgtgaccaa cgaccacatg acacttggtg ttggtccagg tcaaaccaac cgtgtggctt
    33121 ctgttcgcct tgccattgac caagccaaag atcgtctgga cggggcggtc cttgcttcag
    33181 atgccttctt cccatttgcg gataacgtgg aagaaatcgc caaagcagga attaaggcca
    33241 tcatccagcc cggtggctct gtccgtgacc aagaatccat cgaagcagcg gataaatacg
    33301 gcttgactat ggtctttaca ggtgtgagac attttagaca ttaagaagat aaaagggaag
    33361 aaaacagttt ctttcctttt ttggcttaaa atactaactg aaacaagatt aaaacgaact
    33421 tttttgatat aatgttggta aataattcgc aaaagaggtt gaggaatgaa actgcttgtt
    33481 gtcggttctg gtggtcgtga gcatgcgatt gctaaaaagt tacttgaatc aaaagacgtg
    33541 gaaaaagtct ttgtagctcc tgggaatgat gggatgactc tggatggttt ggaattggta
    33601 aatatctcta tttccgaaca ttataaattg attgacttcg caaagaccaa tgatgttgct
    33661 tggaccttta tcggtccaga tgatgccctt gctgctggta tcgtggatga ttttaaccaa
    33721 gctggactta aggcctttgg tccgactagg gctgcagcgg agctggagtg gtccaaggat
    33781 ttcgccaagg aaatcatggt caaatacggc gttccgacag caacatatgg cacattttca
    33841 gatttcgagg aagccaaagc ctatatcgaa aagcatggtg cgcctatcgt agtcaaggcg
    33901 gatggcttgg cacttgggaa gggtgtcgtc gttgctgaga cggttgagca agcggtcgaa
    33961 gccgctcatg agatgctttt ggacaataaa tttggtgact caggtgcgcg cgtggttatt
    34021 gaggaattcc ttgaaggaga ggaattttca ctctttgcct ttgtcaatgg tgataagttc
    34081 tacatcatgc caacggctca ggaccacaaa cgtgcctatg atggcgacaa agggcctaac
    34141 acgggtggta tgggtgccta tgcgccagtc ccacacttac cacagagtgt agttgataca
    34201 gcggttgaca ccattgtcaa gccagttcta gaaggggtga ttaaagaagg tcgcccttat
    34261 ctgggagttc tttacgcagg gcttatcctg acagctgatg gaccgaaagt cattgagttc
    34321 aacgctcggt tcggagatcc agaaactcag attatcttgc ctcgcttgac ctctgacttt
    34381 gctcaaaata tcacagatat cctggatagc aaggagccaa atatcatgtg gacggacaag
    34441 ggtgtgactc tgggtgtggt tgtcgcatcc aagggctacc cgctagacta tgaaaggggc
    34501 gttgagttgc cagccaagac agaaggcgat gtcatcacct actatgcagg ggctaagttt
    34561 gcggaaaata gcagagcact gctctcaaac ggcggacgag tttatatgct cgttaccaca
    34621 gcagataccg tcaaagaagc ccaagccagc atataccaag aactatacca acaaaaaata
    34681 gaaggactct tctaccgaac agatatcgga agcaaggcaa ttaagtaaag atataagaat
    34741 aacgcgccgt agtcgccaaa cacgataatg gtcgtcgtgg tgaaaagacc agaacagtga
    34801 atgttctggt cagggggaaa cttggagacc ttaggctcaa agtttaggaa tgaaaccgaa
    34861 ggtttgcttc cgcctccatc acctaagacc attatcaaaa agaaaaataa aaattcacaa
    34921 aatacgttaa tgatcgtatg gtttgcgagc gttagcgagc taatatagaa caatcaccgc
    34981 cgttgtgaaa gaacgattgg atgataatcc aatcgttcag ggaaattgga agaccttggg
    35041 tttccaattt aggcatgaga cacctttggt ggctgctgcc gtccctcaca agctaaggtg
    35101 attgttgaaa aagaggaaaa aggagaagaa atgaaaccag taatttccat catcatgggc
    35161 tcaaaatccg actgggcaac catgcaaaaa acagcagaag tcctagaccg cttcggtgta
    35221 gcctacgaaa agaaagttgt ttccgcacac cgtacaccag acctcatgtt caaacatgca
    35281 gaagaagccc gtagtcgtgg catcaagatc atcatcgcag gtgctggtgg cgcagcgcat
    35341 ttgccaggca tggtagctgc caaaacaacc cttccagtca ttggtgtgcc agtcaagtct
    35401 cgtgctctta gtggagtgga ttcactctat tctatcgttc agatgccggg tggggtgcct
    35461 gttgcgacca tggctatcgg tgaagctgga gcgactaacg cagctctctt tgccctccgt
    35521 ctcctctctg tagaagataa gtccattgcg gatgcacttg ccaactttgc tgaagaacaa
    35581 ggaaaaatcg cagaggagtc gtcaaatgag ctcatctaaa acaatcggaa ttatcggtgg
    35641 cggtcaactg ggtcagatga tggccatttc tgctatctac atgggccaca aggttatcgc
    35701 gctggatcct gcggcggatt gcccggtctc tcgtgtggcg gaaatcattg tggcacctta
    35761 taacgatgta gacgccctcc gtcagttggc agaccgttgc gatgtcctca cttatgagtt
    35821 tgaaaatgtc gacgctgacg gtttggatgc cgttatcaag gatggacaac tccctcaagg
    35881 aacagatctg ctccgcattt cgcaaaatcg tatttttgaa aaggactttt tgtcaaacaa
    35941 ggctcaagtc actgtggcac cctacaaggt cgtgacttct agcctagact tggcagatat
    36001 cgacttgtcg aaaaactatg tcctcaagac tgcgactggt ggctacgatg gtcatggaca
    36061 aaaggttatt cgttcagaag cagacttgga agcagcctat gcgctagcag actcagcaga
    36121 ctgcgtcttg gaagaatttg tcaactttga ccttgagatt tctgtcatcg tgtcaggaaa
    36181 tggcaaggag gtgacgtttt tcccagttca ggaaaatatc caccgcaaca atatcctgtc
    36241 taagaccatc gtaccagccc gcatttctga aagtctagta gacaaggcta aagctatggc
    36301 agtgcgaatc gcagaacaac tcaacttgtc tggaactctc tgtgtggaaa tgtttgcgac
    36361 agctgatgac atcattgtca atgaaatcgc cccacgacca cataactctg ggcactattc
    36421 tattgaagcc tgtgatttct ctcagtttga cacccatatt ctgggtgttc tcggagcacc
    36481 attaccagtc atcaaactcc atgcgccagc cgttatgctt aatgtcctcg gtcagcatgt
    36541 cgaggctgct gaaaaatatg tcacagaaaa tccaagcgcc cacctccaca tgtatggtaa
    36601 aatagaagca aagcataatc gtaagatggg acatgtgact ttgtttagtg atgtgccgga
    36661 tagtgtggaa gagtttgggg aagggattga tttttaggac aagtctatga tacaaattat
    36721 cgttaataca tttattgaaa agtataagac tggagcagtt gttgaagtgt tgtatgccag
    36781 tgctgaccaa gataaggtac aagctaaata tgaagaacta gctgcacaat accccgaaaa
    36841 ttatttagct atctataatg taccgctgga tacggatttg aatacactag atcattaccc
    36901 gtctgtgttt attggaaaag aggagtttga gtagaaatct tggtttacct agatagctta
    36961 ttcccaacag cttaagaaga aaggaaaaat taacacatga tcaaccgtta ctctcgccct
    37021 gagatggcga atatttggag tgaagaaaat aaataccgtg cttggcttga ggtggaaatc
    37081 ctctctgacg aggcatgggc tgagttgggg gaaatcccta aggaagatgt ggctttgatt
    37141 cgcaagaagg cggactttga catcgaccgt attttggaaa ttgagcagga gacgcgccac
    37201 gatgtggtgg ctttcacgcg tgcggtttct gagactcttg gtgaagagcg caagtgggtt
    37261 cactatgggt taacttctac tgacgtggtg gatactgctt atggttacct ctacaagcag
    37321 gccaacgaca tcatccgtcg tgaccttgaa aacttcacta atatcatcgc tgacaaggcc
    37381 aaggagcaca agttcaccat catgatgggg cgtactcatg gtgtgcacgc tgagccgaca
    37441 acctttggtc ttaaattagc aacttggtac agcgaaatga aacgcaatat cgagcgcttc
    37501 gagcatgcgg ctgctggtgt agaagctggt aagatttctg gtgcggttgg gaactttgcc
    37561 aatatcccac catttgtaga ggagtatgtc tgcgataaac ttggcatccg tgcccaagaa
    37621 atctctacac aagtccttcc tcgtgacctt cacgctgagt actttgcggt tcttgccagc
    37681 attgcgactt caatcgaacg tatggcgact gagattcgtg gtctacaaaa atctgagcaa
    37741 cgcgaagtag aagagttctt tgctaaaggg caaaaagggt cttcagcaat gcctcacaaa
    37801 cgcaacccaa tcggttctga aaatatgact ggtctggcgc gtgtcattcg tggtcacatg
    37861 attacggctt atgaaaacgt cgctctctgg catgaacgcg atatttctca ctcatcagct
    37921 gagcgtatca tcacaccaga tacgaccatt ttgattgact acatgctcaa ccgttttgga
    37981 aatatcgtca agaacttgac agtcttccca gaaaatatga tccgaaacat gaactcgact
    38041 tttggtctta tctttagcca acgggctatg ttgacattga ttgaaaaagg catgacccgt
    38101 gagcaagcct atgacttggt gcaaccaaaa acagcctact cttgggacaa ccaagtagac
    38161 tttaaaccac ttcttgaggc agattcagaa gtaacatcac gtctcacaca agaagaaatc
    38221 gatgaaatct tcaacccagt ttattacacc aaacgagtgg atgatatctt tgaacgtctt
    38281 ggactaggtg attaattaaa aaataaacag cgagcttcaa tctcgctgtt tattttttat
    38341 cgaaaagact tagtcttctt ttcttttagt gagtccatag gctgctagtg tggacatgag
    38401 tcctgcgact actagtcctg cagaatcgtg agttcctgtt tcaggaagtt ttttctctgt
    38461 taccacagga gctggatctt gaggaagaac tttgctttcc tcagcaggag cagttgatgg
    38521 agctggttgg cttgggattt ctagttttgg tttttcttca gcaatagcgg cttgtccgtt
    38581 ttcatcgcct acatgtgtta ccatagttcc gacttcgact atttgagtaa cggcttcctg
    38641 tgctacgaca ctatttacaa gtgttttcac ttccttacca tcggcagaag tgctcacaga
    38701 gtagaagttg ctacgatgtc cattgacgcc cttagtaatg acttgtgttt ttcctttgag
    38761 taagagtgga ttttcacaag tcactgtggt aaatggaatt tcttcttctt ggatatccag
    38821 tctaggtttt acctcagtag ttggtgcaag accactttca tcacccttgt gagttacagg
    38881 agcgccaact tcaaccactt ggtttataac ttctttggtt acctggctat caaggactgt
    38941 ttctgttgtt tttccatttt cagtgagtac agagatgtaa tgagttcgtt cacctttgac
    39001 tcctgctgtg ataatatttt cctgaccggc tgggaggtta ggattttctt tcttgataac
    39061 ttcaaatgga atttcttcag ttcttgtgat gagttctggt ctggtttcaa cattggcagc
    39121 cacttcattt tcatctaggc ttcctgaatg agttacagct ggtttgaggc cttgaagagc
    39181 ggcttttagg ttggctacaa gcgtgtcaag ctcagcttgt ttattacggt tgaggttgta
    39241 atttagagct gttttagctg cgtcaagggc ctcaagactt tctttactat atccttctaa
    39301 gtttgtagga attttagcta attcttcgcg gagagcatta taattagcac gaaagtagtc
    39361 tttgttgtgg tctgcaaagg cagtcatgag ttcaaagatt tcctcttcct tgtattcagc
    39421 gcttggtcta tctgcccaga ttgaaagcat acttccgact gttggaagat ctacttcagg
    39481 atatttggta gaagctagtt gattgaatgg tgtttttcca gtattctcaa tagctttctt
    39541 gaggaaacca ccaccatctt ctggtttttg accaagaatg tagtaccagt caccgttggt
    39601 attcaagaat ttatagcctt tgcttgctag gtattgaggt gatgcgaggt tatatcccca
    39661 ccagccttta gaccagtaag aaatcaagac atctttgtca aactgaacat cgtccttgtc
    39721 ttcatagtag aagccatcgt tgaaggccat tggttgaagc cctctttctt tggccatagc
    39781 tgcgagggtg ttggcatatt cggcaaattt gccatagagt tgataccact tgaggtagta
    39841 ccagccttgg gcactagtcg catcgttggc gtattcgtca gtaccaaagt tgaaaatctt
    39901 tgttttacct gcaaagaagt ccatgtattt accgatgagg gcttttacaa agttcatcgc
    39961 ttcttcgttt ttcaagtcca tagttgtttt tgaaacttta tcaaagtggg cttgaggatt
    40021 tttaatacct aatttttcca tggcaaccag catagcatcc atgtgacctg gactgttaat
    40081 agctgggatg agaccgatgt ccttagattt agcgtattca attagctctg ttacttctgc
    40141 ctgtgttagt gcagtaccgt ttggatcgtc gtagtaagct ttagttcctt cgataatagc
    40201 ttttttaacg tcatcactag cataggtttt tccgttggca gtaatggtca tatcatcgag
    40261 tagaaagcga agtccgtcat ttcctagaag gagatggaca tcagaatatc cgagctcact
    40321 ggccttgtct acgatgcgtt tgagctggtt cagagtaaag tatttgcgtc cagcatcgat
    40381 tgagattacc ttgtttttgg caagtttttc aacctcacgt ttagcttctt cttctttttg
    40441 agcttcaggc gtgagggtca agttgttgac agtttcttga agtttagcaa tggcttgatc
    40501 aatcgtatct tgttgggcac ggctaaggtt gctatcgaga gagcgaatag ctttttcagc
    40561 ttcttttacg gccgtgacgc tttctgcagt ataacggttc aggtcttttg gtacctcgtt
    40621 aagtgcttgc tctgcagatt cataatcagc tgcgaagtat tcagcgttgg catttgcaaa
    40681 atgacgcatg agtttgaaga ggcgtgatgg tgaataacgt gcagatggag tgtcagccca
    40741 agcagctacc ataccaccga tgattgggat atcagctcct tctgtttttg gtacagaagt
    40801 gattggtgtg tttttaatac cattgagccc ctgatcgaga ttgtaccagc cttggccatc
    40861 agcgtttcgt ccaagaacgt agtaccaagc atcattggta ttaaggattt ggtgaccttt
    40921 ttcagctagt agtttagaag aagcgacatc gtagcctccc caaccaccag tccacataga
    40981 aacgatgatg tctttgtcaa aactaccaaa gcttgtgtcg ctattgtagt agataccgtc
    41041 gttaaaagcc attggtttga gaccgtgcga ttttacaata cgagcgaggt cattggcgta
    41101 ggcaataaat ttttcatagc cttttacagg gtagccttcg tttggatagt atttatcagc
    41161 ttgaagcaca ctccaacctt tagcatctgt cgcatcattg gcatattcat caagtccgat
    41221 gttgaagatt tcagtctttt tcgcgaaata agcagcatac ttgtcgataa gggcttttgt
    41281 aaaagcgaca gcttgttcgt tgtcaagatc gacagtacgg gctgatttct tcccaaaata
    41341 gctaaagtta gggttttgga ttcccaattc tttcatggca ttgagaatcg catccatgtg
    41401 tccaggacta tttactgtcg gaatgagacc gataccttta tctttggcat agttaatcag
    41461 atctgtcatt tgactttctg ttaagtgatt gccgtttgga tcgttgtaat aatcatttgt
    41521 acctttttca atggcgcgtt tgacatcgtc actggcatag gtcttgccgt tagctgtgat
    41581 gctcatatcg tccaacatga aacggagtcc atcatttccg actaataggt gtaaatcagt
    41641 gtagccataa tgtttcgctt tatcgatgat ttccttgagc tgttctggtg agaaatattt
    41701 acgtccagca tcaatagaaa caattttctt tttcgctagt ttttcattta cagttgcagc
    41761 acgttccttt cctgcctctg ttgccggttt gtcagcctct gctttcgctt catctttttt
    41821 agctggttta tccttgtcag tcttgtctgt atttgactct ttagaatcaa cctctttcgc
    41881 ttcttccttt ttagggctag cttcttctgc ctttttatta gcagtttctt tttcagcaga
    41941 agttggagtt accacttctg ctttatcact aggagttgaa ctaacttcct cttgtggttt
    42001 ttcttctgtt tttggaagac tagctacctt atcagtagct ggagtttctg tttctacagt
    42061 ttttggagct tctggttgaa gcactgcttt aggtgtttcc tcagtccgat tttcggatga
    42121 ttgaggggaa tcagaaaccg tatggatggt cggttggttt tctgtagtag taggagtaac
    42181 tccatcggct gcaacagtct gtgcttggaa ggcaaatcca attagaacag aagctgctcc
    42241 tacagcgtat ttacgaatag aaaaacgctg ttgtttttca tgtttcattg caaaacctcc
    42301 tgattgcatt gttatattga tagcgattat ataaatcaac gcctttattt tatttcttat
    42361 attaatttct tatattaacg agagtcaaga ggagatgaca aaaaactata ataagtataa
    42421 aaaaatataa aatttaaact taagatttca gattggtcgg aaaaaatacg tatatatatc
    42481 tagtataatt tttggttcta tttctataaa atattccaca aattatagaa ttttccaaaa
    42541 ataggtaagc gctacctttt tggtgtagta taataagcat agaaaaagcc caagcgatta
    42601 gctcaggttt tcttcttagt gatcacggtc acatgagata aatttaatct tgtagtaatc
    42661 agatcgtttg taagtttcac tgtattctaa aacttggcca gttgattcga gtttggtgat
    42721 tttagtttgt aggacagtag ggaattgttc atcgactccg aggactgaag ctgcatgttc
    42781 tggagttgga aagactattt cgttgatttc ttcaaagtgt tcatcattca tgtgaatgtg
    42841 gtagtctaac ttgaaacgat tatagataga actatagtat tcaaggtttg gataatttgc
    42901 gttgatatat tgttctggga tgtaggatgt atggtagata taaacgacac cgtttgattc
    42961 gcggatacgt tcaatcttgt agtagaattg atcgccgcgt agacccaatt tttccaagta
    43021 aacaagcttg tttccgcgtt caattgaaag aacagttacc ttatcatctt tagcattgaa
    43081 gagttcaata tctgaaaact ctacaagctt gtgtttgcgt gcacgtgaaa cgaaggttcc
    43141 ttttccttgt tggcggacaa tatagccatc tttggcaagg tcgtttaagg cgcgaacaac
    43201 tgtgatagag ctgacatcgt acattgaaat gagttctgct tcagtgtaaa atttatctcc
    43261 actgctaaac tgcccagaga tgattttatt ttttaattcg tcttttatgt attgatattt
    43321 gggaattgcc atatttttac ctctattttc cttcttccat agaaaatttt accataaaag
    43381 cgaaaaaaat agtagtcttt tgaataaaaa attagaataa tagtttgaaa aattaagcga
    43441 tatagggatt gctcatattt tataaatgta ttctatacaa aattatttta ggtcctatat
    43501 tccgaattta aagagcgttt gaaatgggtc taaaaatgtt tgaaactaat tgaatgtgtg
    43561 tataatagta aaaatgcagt aaatatcccg acaatttcta ttgacaattc aaacagattg
    43621 gtttataatt aatataacaa caaatgaaag cgcaaacttt cgcggtcgga aggtagtttt
    43681 atgacacgat ttgagatacg agatgatttc tatctcgatg gaaaatcatt taagatttta
    43741 tctggtgcca ttcattattt tagggttcct ccagaggatt ggtatcattc gctctataac
    43801 ttgaaggctc ttggttttaa tacggtagag acttatgttg cttggaattt acacgagcct
    43861 tgtgaaggtg agtttcattt tgaaggtgat ctggatttag agaaatttct ccaaatagcg
    43921 caggatttgg gtctctacgc aattgtgcgt ccgtctccat ttatctgtgc ggaatgggaa
    43981 ttcggtggct taccagcttg gctcttgacc aagaacatgc gaattcgctc atccgaccca
    44041 gcatatatcg aggcagttgg tcgctactat gatcagttat tgccaagact ggtgcctcgt
    44101 ttgttggaca atggtggcaa tattctcatg atgcaggttg aaaatgagta tggttcttac
    44161 ggagaagata aggcttacct gagagcgatt cgacagctaa tggaagagtg tggcgtaacc
    44221 tgtcccctct ttacatcaga tggtccatgg cgagctactc tgaaagctgg aaccttaatt
    44281 gaagaggacc tctttgtaac aggaaacttt ggttctaagg caccttacaa cttttcgcag
    44341 atgcaggaat tctttgatga acatggtaag aaatggccac tcatgtgtat ggagttctgg
    44401 gatggttggt tcaatcgctg gaaagaaccg attatcacac gggatcctaa ggaattggca
    44461 gatgcagttc gagaggtttt ggaacaaggc tctatcaatc tttacatgtt ccacggtggt
    44521 acaaactttg gtttcatgaa tggttgctca gctcgaggaa ctttggacct gccacaagtt
    44581 acgtcttatg attacgatgc ccttctggat gaagaaggaa atccaactgc taaatatctt
    44641 gcagtcaaga agatgatggc aacacatttt tcagagtatc cgcagttgga accactctac
    44701 aaagagagta tggagttgga tgctattcca ctagttgaaa aagtttcttt gtttgaaacc
    44761 ttagatagct tgtcaagtcc tgtagaaagt ctctatcctc aaaagatgga ggagctggga
    44821 caaagttatg gctacctact ttatcgaaca gaaacaaact gggatgcaga agaagaaaga
    44881 cttcgtatca ttgatggtcg agatagggcc cagctgtatg tcgatggtca gtgggttaaa
    44941 actcaatatc agacagagat tggggaagat attttttatc aaggtaaaaa gaaagggcta
    45001 tctaggttag atatcttgat agaaaatatg gggcgtgtca actatgggca taagttctta
    45061 gcggatacgc aacgtaaggg aattcggaca ggggtctgta aggatctgca tttcttacta
    45121 aactggaaac actatccact cccactagac aatcctgaga aaattgattt ttcaaaagga
    45181 tggactcaag gacaaccagc cttttacgct tatgacttta cagtcgaaga gccaaaagat
    45241 acttacctag acttgtctga gtttggtaag ggggttgcct ttgtcaatgg gcagaatcta
    45301 ggacgttttt ggaacgttgg cccaactctc tcactttata tccctcatag ctatctcaag
    45361 gaaggtgcca accgcatcat tatctttgaa acagaaggtc aatataaaga agagattcat
    45421 ttaactcgta aacctacact aaaacatata aagggggaaa acttatgaca attgtaggat
    45481 gccgtattga tggacgtttg atccacggac aagtagccaa tctttgggct ggaaaactaa
    45541 atgtttcacg cattatggtt gtagacgacg aagttgtcaa caacgatatt gaaaagagtg
    45601 gtttgaaact tgcgacacca ccaggtgtga aattgagtat tttgccagtt gagaaagctg
    45661 cagccaatat tcttggtggc aaatacgata gccaacgtct ctttatcgtg gctcgtaaac
    45721 cagaccgctt ccttggtttg gtagaagcag gtgtaccact tgaaaccctt aatgttggga
    45781 atatgtctca aacaccagaa actcgttcta ttacacgttc tatcaacgta gtagacaagg
    45841 atgtggaaga cttccacaaa ctggcagaaa aaggtgttaa acttactgct cagatggttc
    45901 caaatgatcc aatttcagac tttttgagct tattaaaata ggaaaaaaat ttttaggagg
    45961 tcattgttat gatacaatgg tggcaaattt tacttctcac tttgtactca gcttatcaaa
    46021 tctgtgatga gttgacgatc gtttcatctg caggttcccc tgtatttgct ggtttcatta
    46081 ctggtttaat catgggagat gtgactactg gtttacttat cggtggtaac ttgcaactgt
    46141 tcgttcttgg ggttggtacc ttcggtggtg cttctcgtat cgacgcaact tctggtgcgg
    46201 ttcttgcgac agccttctct gtttcacaag gaattgatgc accgcttgcc attactacaa
    46261 tcgctgtacc agtagcagct ctcttgactt acttcgacgt tcttggtcgt atgactacta
    46321 ccttcttcgc tcaccgtgtg gatgctgcaa tcgaacgctt tgactataaa ggtattgaac
    46381 gcaactactt gcttggtgcg attccgtggg ctctatctcg tgcccttcca gtcttctttg
    46441 cccttgcttt tggtggtgcc tttgtacaat cagtagtaga cttcgttgaa gcctacaaat
    46501 gggttgcaga tggcttgaca cttgcaggac gtatgcttcc aggtcttgga tttgcaatct
    46561 tgcttcgtta ccttccagtt aaacgtaacc ttcactacct tgctatggga tttggtttga
    46621 cagctatgtt gactgttctt tactcatatg taacaggtct tggtggcgct gttgctggta
    46681 tcgtaggtac tcttcctgct gaagttgctg aaaaaattgg tttcgtgaac aacttcaaag
    46741 gtttgtctat gattggtatt tctatcgtag gtattttcct tgcagtgctt cacttcaaaa
    46801 atagccaaaa agtagctgta gcagcacctt ctacaccatc agaaagtggg gaaatcgaag
    46861 atgacgaatt ctaattacaa acttacaaaa gaagatttta atcacatcaa caaacgtagc
    46921 ttgtttactt tccaattagg ttggaactac gaacgtatgc aagcttctgg ttacctttac
    46981 atgatcttgc ctcagttgcg taaaatgtat ggtgatggaa ctcctgaatt gaaagaaatg
    47041 atgaaagttc atactcaatt cttcaatact tcaccattct tccataccat tatcgctggt
    47101 tttgaccttg ccatggaaga aaaagatggt gtaggttcaa aagacgccgt taacggtatc
    47161 aagacaggtt tgatgggacc attcgctcct cttggggata caatctttgg ttcacttgta
    47221 cctgctatca tggggtcagt cgcagcaact atggctatcg ctggccaacc ttgggggatc
    47281 ttcctttgga ttgcagttgc agtagcgtat gacatcttcc gttggaaaca gttggaattt
    47341 gcttacaaag aaggggttaa ccttatcaac aacatgcaaa gtaccttgac agctttgatt
    47401 gacgctgcat ctgtacttgg tgtcttcatg atgggtgctc ttgtagcaac agtgattaac
    47461 tttgaaattt cttacaagtt gccaatcggt gaaaagatga ttgatttcca agacatcttg
    47521 aaccaaatct tcccacgttt gcttccagca atctttactg cctttatctt ctggttgctt
    47581 ggtaagaaag gtatgaactc tactaaagct atcggtatta ttatcgtact tgctttggct
    47641 ctttctgccc ttggtcactt tgcacttgga atgtaattcc ttatgactaa atcattaatt
    47701 ttggtgagcc atggtcgctt ctgtgaggag cttagaggta gcacagaaat gattatgggc
    47761 ccacaagaca acatttacac agtagctctt cttccagaag atggcccaga agaatttact
    47821 gctaaatttg aagctgttat tgaaggattg gatgatttcc tagtctttgc ggatcttctc
    47881 ggtgggacac cttgtaatgt ggtgagtcgc ttgatcatgg aaggtcgtga tattgacctt
    47941 tacgcaggga tgaatcttcc aatggtgatt gaatttatca atgcgagcct tacaggcgca
    48001 gatgcggact acaagagccg tgctgcagaa agcattgtga aagttaatga cctgttagcg
    48061 ggcttcgatg atgacgaaga tgaataatac tcttcgaaaa tctcttcaaa ctacgtcaac
    48121 gtcgccttgc cgtaggtata tgttactgac ttcgtcagtc ttatccggca acctcaaaac
    48181 ggtgttttga gctgacttcg tcagtcttat ccggcaacct caaagcagtg ctttgagcag
    48241 cctgcggcta gtttcctaca gattttagtt ggaactcgat tcaattcatg tgacaacgtg
    48301 aaaatcgtta gagcatttta tatagaatat acatgggaat gtagcttact cccattccca
    48361 tatttaatag aaaaagagga actcaatgct acattataca aaagaagact tgctcgaatt
    48421 gggtgcagaa atcactacgc gtgaaatcta ccaacagcct gatgtatgga gagaagcttt
    48481 tgaattttat caagcaaaac gtgaagaaat tgcagccttc ctacaagaaa tcgctgataa
    48541 acatgactat attaaggtta tcttgacagg tgctgggact tctgcttatg tgggagatac
    48601 cttgctacct tattttaagg aagtctatga cgaacgcaaa tggaatttca atgctattgc
    48661 gacaacagat atcgttgcca atccagcaac ctatttgaaa aaagatgtgg caactgtcct
    48721 tgtgtctttt gctcgtagtg ggaattcgcc tgaaagtttg gcgactgttg atttggccaa
    48781 atccttggtg gatgagcttt atcaagtgac gattacttgt gcagcagatg gtaaattggc
    48841 tcttcaagct cacggtgatg atcgtaatct cttgctcttg caaccagctg tctctaatga
    48901 tgctggattt gccatgactt ctagctttac gtctatgatg ttgacaactc tcttggtctt
    48961 tgatcctaca gaatttgctg ttaagtctga acgttttgaa gttgtatcta gtcttgcccg
    49021 taaagtttta gacaaggcag aagatgtcaa agagctcgtt gatttatact ttaaccgtgt
    49081 catctatcta ggcgctggtc ctttctttgg acttgctcat gaagctcagc tcaagatttt
    49141 ggaattaact gctggtcaag ttgcgaccat gtatgaaagc ccagttggct tccgtcacgg
    49201 tccaaaatct cttatcaacg acaatacagt tgttttggtc tttggtacaa cgacagacta
    49261 cactcgtaag tacgacttgg acttggttcg tgaagttgct ggtgaccaga ttgctcgtcg
    49321 tgttgtgctt ttgagtgatc aagcttttgg tcttgaaaat gtcaaagaag tggcccttgg
    49381 ttgtggcggt gtcttgaatg atatttaccg tgtcttccct tacatcgttt atgcccaact
    49441 ctttgcttta ttgacttcac tcaaggtaga aaataaacca gatacaccgt ctcctacagg
    49501 tacagtaaac cgtgtagtac aaggtgtcat aattcacgaa tatcaaaagt aagacagtgt
    49561 ttatgaattc ttgacaagag gatttgtaaa ttatcagata aaccatagat tgtcagtacg
    49621 ctttctatgg tttgtttgct tgagagaaat agtaaaagga gaacagaatg aaagcataca
    49681 cagagcgtgt atttggaaat gttgagggtg aggatgtctt ggcctatcga tttgagacag
    49741 acggtggcta ccaacttgag gttatgactt atggtgcgac tatcttgcgc tatgtcgcac
    49801 ctgacaaggc tggaaatttt gccaatgtta tcttgggatt tgatgacttt gatagttatg
    49861 taggcaatag tcccaagcat ggagcaagtg taggtcctgt agcgggtcgt attgcaggtg
    49921 cgacctttga gctcaatggt aagacctatg accttgaggt taataatgct agcaactgta
    49981 atcacagtgg ttcaactggt tgggattcca gcttgtttga agttgaagaa gtaagcgatc
    50041 atggcttgac tctctacaca gagcgtacag atgggacagg agggttccct ggaaatctca
    50101 agatttggat cagttatcac ttggaagaaa ctggtgccta tgaaatcagc tacaaggtaa
    50161 cgaccgatca ggatacgctg gtcaatccaa ccaaccacag ctatttcaac ttgtctggtg
    50221 atttcacgca gacgattgac cgtcatgtct tccaactaaa cacagagggc atttactcaa
    50281 tcgctcctga cggtgttcct gccaaaactc cagaagccaa ccgtgatgtg gtcaaacacg
    50341 tctacaatgg taccttgttg aaggatatct ttgcagaaga agatgagcaa atccagctgg
    50401 catcaggttt ggatcatcca tttgcccttc ctgcaggcca tgacaatgct ggattccttt
    50461 atgaccaaaa ttcaggtcgc ttcctgcttt tcaagacaga agctccttgc tttgtggtct
    50521 acacagcaaa ctttgtggat gaaagtgtca tcataggagg tcagccaatg ctacagcaca
    50581 atgggattgc tcttgaagcg caagctttac cagatgccat tcacagtgac cttaaaggcc
    50641 aagtcattct taaagctggt caaaccttca ccagtaagac acgttatgaa cttgttgtga
    50701 agtaaaagag tcattgcgcc tacttttggg agctaggaat aggtacgcag agacaaatag
    50761 taggaaaata tgatataact aagcgttgaa agctatctgt taatataata ttcaaactac
    50821 aataaggagt aagaaagaaa cgaagaaaat tgtatttgct agtgccttgg ctttgacctt
    50881 ggctggagca gttttgacaa atgatgtttt tgcgaacgac agacttgtgg caacacaaac
    50941 tactgatggt aaaaatgaaa atgtattgac ctcagaggtg ctaaaacctt ctagtggcaa
    51001 tgttttggtt ggaatcaaag gagaatttgt ggctcctcat caacaatcta ttttggatgc
    51061 catcaatgct atctgtaaag aagcggctga cgaaggtttg gtagataagt atgtccctat
    51121 caaatgatca actgacctag aaaaggcagc ttttgccaga gctacagaag catctataac
    51181 catggatcat acccgtcttt ctagcaaaga tctttggagt gcctttccaa cttctaatag
    51241 tataatggga gaaaatttgg catggaatca tgacggtttt ctaaaagcta ttgaacaatg
    51301 gcgtgctgaa aaagcagatt atgtggagaa aaaaatagtg gttcagacaa cgggaaatct
    51361 ggtcactatg agtcgctaat taaccctaaa tttacacaca tggggatggc agcttttaaa
    51421 aatcctaaca atcaatacaa agctattaca attgctcaaa ctctaggtga tgatgcttct
    51481 tcagaggaat tggctggtag atatggttct gctgttcagt gtacagaagt gactgcctca
    51541 aacctttcaa cagttaaaac taaagctacg gttgtagaaa aaccactgaa agattttaga
    51601 gcgtctacgt ctgatcagtc tggttgggtg gaatctaatg gtaaatggta tttctatgag
    51661 tctggtgatg tgaagacagg ttgggtgaaa acagatggta aatggtacta tttgaatgac
    51721 ttaggtgtca tgcagactgg atttgtaaaa ttttctggta gctggtatta cttgagcaat
    51781 tcaggtgcta tgtttacagg ctggggaaca gatggtagca gatggttcta ctttgacggc
    51841 tcaggagcta tgaagacagg ctggtacaag gaaaatggca cttggtatta ccttgacgaa
    51901 gcaggtatca tgaagacagg ttggtttaaa gtcggaccac actggtacta tgcctacggt
    51961 tcaggagctt tggctgtgag cacaacaaca ccagatggtt accgtgtaaa tggtaatggt
    52021 gaatgggtaa actaggctca ggccataggt aaagcattca tcttacttag caaaaagaat
    52081 gaacgataag aaagaggttg atggcgaaca ttggcctctt ttgatttata aagattggat
    52141 tcttgtcgcc tcaatttcag acttttctat tgtaagctaa tattttatag cccattaaaa
    52201 gcataagcgg taatctaatt taaaaaatgc tgtaattagt ctgaagtcca cacttacttg
    52261 ttgagatgtt atctctgttt tttatcgtta taatttactg tattttttat agtatgcaga
    52321 atatttttaa gtatatttca atagaaattt ctatcgattt attgtataat gataagtaat
    52381 tgttgaaaag tactcagaaa attccatact atattatttt tatgtttata cttttatgct
    52441 ataaaatata gattgatata aagaatatag aaaaagcgag gttaatatga gccgaaaaag
    52501 cattggtgag aaacgccata gtttctcgat gagaaagttg tcagtgggat tggtatcagt
    52561 tactgtatct agtttctttt tgatgagtca agggattcaa tcggtatcgg ccgataatat
    52621 ggaaagtcca attcattata agtatatgac cgagggtaaa ttgacagacg aggaaaaatc
    52681 cttgctggta gaggcccttc cacaactggc tgaagaatca gatgatactt attacttggt
    52741 ttatagatct caacagtttt taccgaatac aggttttaac ccaactgttg gtactttcct
    52801 ttttactgca ggattgagct tgttagtttt attggtttct aaaagggaaa atggaaagaa
    52861 acgacttgtt cattttctgc tgttgactag catgggagtt caattgttgc cggccagtgc
    52921 ttttgggttg accagccaga ttttatctgc ctataatagt cagctttcta tcggagtcgg
    52981 ggaacattta ccagagcctc tgaaaatcga aggttatcaa tatattggtt atatcaaaac
    53041 taagaaacag gataatacag agctttcaag gacagttgat gggaaatact ctgctcaaag
    53101 agatagtcaa ccaaactcta caaaaacatc agatgtagtt cattcagctg atttagaatg
    53161 gaaccaagga caggggaagg ttagtttaca aggtgaagca tcaggggatg atggactttc
    53221 agaaaaatct tctatagcag cagacaatct atcttctaat gattcattcg caagtcaagt
    53281 tgagcagaat ccggatcaca aaggagaatc tgtagttcga ccaacagtgc cagaacaagg
    53341 aaatcctgtg tctgctacaa cggtgcagag tgcggaagag gaagtattgg cgacgacaaa
    53401 tgatcgacca gagtataaac ttccattgga aaccaaaggc acgcaagaac ccggtcatga
    53461 gggtgaagcc gcagtccgtg aagacttacc agtctacact aagccactag aaaccaaagg
    53521 tacacaagga cccggacatg aaggtgaagc tgcagttcgc gaggaagaac cagcttacac
    53581 agaaccgtta gcaacgaaag gcacgcaaga gccaggtcat gagggcaaag ctacagtccg
    53641 cgaagagact ctagagtaca cggaaccggt agcgacaaaa ggcacacaag aacccgaaca
    53701 tgagggcgaa gcggcagtag aagaagaact tccggcttta gaggtcacta cacgaaatag
    53761 aacggaaatc cagaatattc cttatacaac agaagaaatt caggatccaa cacttctgaa
    53821 aaatcgtcgt aagattgaac gacaagggca agcagggaca cgtacaattc aatatgaaga
    53881 ctacatcgta aatggtaatg tcgtagaaac taaagaagtg tcacgaactg aagtagctcc
    53941 ggtcaacgaa gtcgttaaag taggaacact tgtgaaagtt aaacctacag tagaaattac
    54001 aaacttaaca aaagttgaga acaaaaaatc tataactgta agttataact taatagacac
    54061 tacctcagca tatgtttctg caaaaacgca agttttccat ggagacaagc tagttaaaga
    54121 ggtggatata gaaaatcctg ccaaagagca agtaatatca ggtttagatt actacacacc
    54181 gtatacagtt aaaacacacc taacttataa tttgggtgaa aataatgagg aaaatactga
    54241 aacatcaact caagatttcc aattagagta taagaaaata gagattaaag atattgattc
    54301 agtagaatta tacggtaaag aaaatgatcg ttatcgtaga tatttaagtc taagtgaagc
    54361 gccgactgat acggctaaat actttgtaaa agtgaaatca gatcgcttca aagaaatgta
    54421 cctacctgta aaatctatta cagaaaatac ggatggaacg tataaagtga cggtagccgt
    54481 tgatcaactt gtcgaagaag gtacagacgg ttacaaagat gattacacat ttactgtagc
    54541 taaatctaaa gcagagcaac caggagttta cacatccttt aaacagctgg taacagccat
    54601 gcaaagcaat ctgtctggtg tctatacatt ggcttcagat atgaccgcag atgaggtgag
    54661 cttaggcgat aagcagacaa gttatctcac aggtgcattt acagggagct tgatcggttc
    54721 tgatggaaca aaatcgtatg ccatttatga tttgaagaaa ccattatttg atacattaaa
    54781 tggtgctaca gttagagatt tggatattaa aactgtttct gctgatagta aagaaaatgt
    54841 cgcagcgctg gcgaaggcag cgaatagcgc gaatattaat aatgttgcag tagaaggaaa
    54901 aatctcaggt gcgaaatctg ttgcgggatt agtagcgagc gcaacaaata cagtgataga
    54961 aaacagctcg tttacaggga aacttatcgc aaatcaccag gacagtaata aaaatgatac
    55021 tggaggaata gtaggtaata taacaggaaa tagttcgaga gttaataaag ttagggtaga
    55081 tgccttaatc tctactaatg cacgcaataa taaccaaaca gctggaggga tagtaggtag
    55141 attagaaaat ggtgcattga tatctaattc ggttgctact ggagaaatac gaaatggtca
    55201 aggatattct agagtcggag gaatagtagg atctacgtgg caaaacggtc gagtaaataa
    55261 tgttgtgagt aacgtagatg ttggagatgg ttatgttatc accggtgatc aatacgcagc
    55321 agcagatgtg aaaaatgcaa gtacatcagt tgataataga aaagcagaca gattcgctac
    55381 aaaattatca aaagaccaaa tagacgcgaa agttgctgat tatggaatca cagtaactct
    55441 tgatgatact gggcaagatt taaaacgtaa tctaagagaa gttgattata caagactaaa
    55501 taaagcagaa gctgaaagaa aagtagctta tagcaacata gaaaaactga tgccattcta
    55561 caataaagac ctagtagttc actatggtaa caaagtagcg acaacagata aactttacac
    55621 tacagaattg ttagatgttg tgccgatgaa agatgatgaa gtagtaacgg atattaataa
    55681 taagaaaaat tcaataaata aagttatgtt acatttcaaa gataatacag tagaatacct
    55741 agatgtaaca ttcaaagaaa acttcataaa cagtcaagta atcgaataca atgttacagg
    55801 aaaagaatat atattcacac cagaagcatt tgtttcagac tatacagcga taacgaataa
    55861 cgtactaagc gacttgcaaa atgtaacact taactcagaa gctactaaaa aagtactagg
    55921 agcagcgaat gatgcagcct tagataacct atacttagat agacaatttg aagaagttaa
    55981 agctaatata gcagaacacc taagaaaagt attagcgatg gataaatcaa tcaatactac
    56041 aggagacggt gtagttgaat acgtaagtga gaaaatcaaa aataacaaag aagcatttat
    56101 gctaggtctt acttatatga accgttggta cgatattaat tatggtaaaa tgaatacaaa
    56161 agatttatct acgtacaagt ttgactttaa cggaaataat gagacttcaa cgttggatac
    56221 tattgtcgca ttaggaaata gtggactaga taacctgaga gcttcaaata ctgtaggttt
    56281 atatgcgaat aaacttgcat cggtaaaagg agaagattca gtctttgact tcgtagaagc
    56341 gtatagaaaa ctgttcttac caaacaaaac aaataacgag tggtttaaag aaaatacaaa
    56401 ggcatatata gtcgaaatga agtctgatat tgcagaagta cgagaaaaac aagaatcacc
    56461 aacagccgat agaaaatatt cattaggagt ttacgataga atatcagcac caagttgggg
    56521 gcataagagt atgttattac cactactaac tttacctgaa gaatctgtgt atatttcatc
    56581 gaatatgtct acacttgcat tcggttcgta tgaaagatat cgtgatagtg tggatggagt
    56641 tattctttca ggagatgctt tacgaactta tgtaagaaat agagttgata tagcagcgaa
    56701 aaggcataga gaccattatg atatttggta caatcttctt gacagtgctt caaaagaaaa
    56761 acttttccgt tctgtgatag tttatgatgg attcaatgta aaagatgaga caggaagaac
    56821 ttattgggca aggttaacgg ataaaaacat cggctctatt aaagaattct tcggacctgt
    56881 tgggaaatgg tatgagtata atagtagtgc aggagcgtat gcgaatggaa gtttaacgca
    56941 ctttgtgtta gatagattat tagatgctta tggaacgtcg gtttatactc atgaaatggt
    57001 tcataattct gattctgcaa tctactttga aggaaatggt agacgtgaag gattgggagc
    57061 ggagttatac gcacttggtt tactgcaatc tgtagatagt gtaaattctc atattttagc
    57121 tttaaatacg ttatataaag cagaaaaaga tgatttgaat agattgcata catataatcc
    57181 ggtggaacgt ttcgattcgg atgaggcgct tcaaagttat atgcatggat catatgatgt
    57241 aatgtataca cttgatgcga tggaagcaaa agcgatatta gctcaaaata atgatgttaa
    57301 gaaaaaatgg tttagaaaaa tagaaaatta ttacgttcgt gatactagac ataataaaga
    57361 tacacatgca ggaaataaag tccgtccatt aacagatgaa gaagtagcta acttaacatc
    57421 gttaaactca ttaatcgaca acgacatcat aaatagacgt agctatgatg ataatagaga
    57481 atataaacga aatggctact atactataag tatgttctct cctgtatacg cagcgctaag
    57541 caattcgaaa ggtgctcctg gagatattat gtttagaaaa atagcttatg aattacttgc
    57601 ggaaaaaggt tatcacaaag gattcctacc ttatgtttct aatcagtacg gagcagaagc
    57661 atttgccagc ggaagcaaaa cattctcatc atggcatgga agagatgttg ctttagtgac
    57721 agatgattta gtatttaaga aagtattcaa tggtgagtac tcatcatggg ctgatttcaa
    57781 aaaagcaatg tttaaacaac gtatagataa acaagataat ctgaaaccaa taacaattca
    57841 atacgaatta ggtaatccta atagtacaaa agaagtaact ataacaacgg ctgcacaaat
    57901 gcaacaatta attaatgaag cggctgcgaa agatattact aatatagatc gtgcaacgag
    57961 tcatacccca gcaagttggg tgcatttatt aaaacaaaaa atctataatg catatcttcg
    58021 cactacagat gactttagaa attctatata taaataagat tgtagagttt cattgttgag
    58081 tagtgtttct tgtaaggatg aggagtcaga tgacaaatcg actccttttt cttatggatc
    58141 gatgtagaga tttgattgaa tgcagattgc aggaatcatc ttcaactcat caacgaccaa
    58201 tggtgacaag gtggatttca atcccacaga aaatgttgat ttgagaaata actttgctag
    58261 tctagtaaaa taaatacaaa acaatcctag aagatttttt ctgggattgt tttttgctga
    58321 gtgggatgct tcaagttgtc tggcttgact ttcttgaggg aagttatata atagttgtaa
    58381 taattaaagt tacaataaaa gaggaaatat ttatgacata tgaataccag agccacattt
    58441 atttagcaga ggcagtttta aatgtgaagg atttggtcag tcaaacagtt ttttatcagc
    58501 agattattgg tttagaaatc ctatctcaaa cggatacaga ggtcgttctg ggacttggag
    58561 gaaaagcctt ggtacacttg attcaagcac aagagggtgg agaagtaagg gaacattatg
    58621 gtctttacca tctggctatt cttttgccga cacgaaaggc tttggcggat gtcttgaagc
    58681 acctgacgga tttacagatt cctcttgttg gcggtgcaga tcacggttac agtgaggccc
    58741 tttacttaga ggacttggag ggaaatggca ttgaactcta tcgagataag ccagtttcca
    58801 catgggatat tcgagaagat ggacgtatta tcggggtgac tgaagtcctt gcggctcagg
    58861 atatctatga gttgggggaa agagtagagc cttttatcct agcagagggt acgagaatgg
    58921 ggcatattca tctttctgtc aaggatagtc gaaagtccag acagttttat caaacggtgt
    58981 tagggctcga ggataaattc agtgtgccta gtgctagttg gatcgcagct ggggactacc
    59041 atcatcattt agcagtcaac gaatggggag gaaaaggtct ggatccgcgt aaacaagtcc
    59101 taccaggttt agcctactat gtcatcgaag tcgcacataa agaagaactg ttaacgattg
    59161 cccaacgagc acaagaagtt gacgcaccaa tcaaatggat gacatcgatc caattggaaa
    59221 tcacagactc agatggcatc gtgacccgta ttcgtttagc tagatagatg gtatgtgatg
    59281 aaggtagagc atcaattgta gaaagtgctc cttattctag tcagatacgt ggaaaatttg
    59341 atatgatagt agggaataag gagaagaata atatgactag cgaataccag aaaatgatag
    59401 caggagagtt ttaccgtcca tcagacccag aactgagagc cttagctcag gcttctcgcc
    59461 aaaaacaggc cgcctttaac aaggaagaga accccttgaa gggagccgaa atcatcaaga
    59521 cttggtttgc ctcaaccggg aaaaatcttt acatcaacac tcgcttgatg gtggactacg
    59581 gtgtcaacat ccatctaggg gaaaattttt attctaattg gaacttgacc atgctggata
    59641 tctgtcccat tcgtatcggg gacaatgcta tgattggtcc taattgtcag tttttgacac
    59701 ccctccatcc actagatcca caggaacgca attcaggtat cgagtacgga aagcctatca
    59761 caatcggaga taatttctgg actggtggtg gcgtcattgt ccttcctgga gtgacactgg
    59821 gaaataatgt cgttgcagga gcaggggcag taattaccaa atcttttggc gacaacgttg
    59881 tcctagctgg caatcctgcg cgcgtgatta aggaaatacc tgttaaatag aagtaaaaag
    59941 gaacagctgg ggttgtttct tttttgtagg tttcatcatt ttttacccag ttcacattta
    60001 cctactctat ctcttagcaa gtctgtttca ttaagcaagt tcaaagcatc tcgtaagtgg
    60061 gatgtttttc tcctcagttc atcagcttcc tccttgacac tcggtcagat tttgatacaa
    60121 tagtacaaaa ttagaggagg caggctatga ttcagaaaca tgcgattcct attttagagt
    60181 ttgatgacaa tcctcaggcg gttatcatgc ccaatcacga ggggctggac ttgcagttgc
    60241 caaagaagtg tgtttatgca tttttaggtg aggagattga ccgctatgcg agggaagtag
    60301 gggcgaactg tgttggcgaa tttgtttctg ccaccaagac ctatccagtt tatgtcgtga
    60361 actacaagga cgaggaggtc tgtctggctc aggctcctgt tggctccgct ccagcagccc
    60421 agtttatgga ttggttgatt ggctatggtg tggagcagat tatctctact gggacctgtg
    60481 gtgtcctagc tgatatagag gaaaatgcct ttctagtccc tgttcgcgct ctgcgagatg
    60541 aaggagccag ttaccactat gtggcacctt gtcgttatat ggaaatgcag ccagaggcta
    60601 ttgctgctat tgaggaagtt ttggaagaca gagggattcc ttatgaagaa gtcatgacct
    60661 ggacgacaga cggtttttac cgagaaacgg ctgaaaaggt ggcttatcgt aaggaagaag
    60721 gctgtgctgt tgtggagatg gagtgttctg ctcttgcggc agtagctcaa ttgcgtgggg
    60781 ttctctgggg tgaattgttg ttcacagcag attctctagc ggacttggac cagtacgaca
    60841 gtcgtgactg gggctcggaa gcttttaata aggcgctaga actgagttta gcaagtgttc
    60901 accaccttta gttgtactgg caaaggattt gttttatcat aaaatgtcta gctcatactt
    60961 ttcaaaaata tgtttaaacg aggtcacctt cctcttgtcc taggcatgtt gaggttggga
    61021 aaaatcttta aaatcagaaa aacgtatcat atcaggtgat gaaaactttg acactatgcg
    61081 ttttatgtcg ataagattta gagtgagatg aaatgatact cttcgaaaat ctcttcaaac
    61141 caggtcagct tcaccttgcc gtaggtatat gttactgact tcgtcagtct tatccggcaa
    61201 cctcaaaacg gtgttttgag ctgacttcgt cagttctatt tgcaacctca aaacagtgtt
    61261 ttgagcaacc tgtgactagc tttctaatcg atgccttggt tttcattgcc tataatcaaa
    61321 aagagaaatt ttctcctgaa aagcatatag agtagctggc gttaaaagct cctgtcttgc
    61381 ttttttgacc tatagtcaca tctatcaagt attgttcttg cctaagctat caataaaaag
    61441 gtggcatttt ttaggcttgg tgttagtaga ttttgcctta tcctatctaa gtcatttcga
    61501 actttttatg gtacaatgga aacatgttat tcaaattatc taaggaaaaa atagagctag
    61561 gcttatctcg tttatcgcca gcccgtcgta tttttttgag ttttgccttg gtcattttac
    61621 taggctctct tcttttgagc ttgccctttg tccaagttga aagctcacga gcgacttatt
    61681 ttgatcatct tttcactgct gtctctgcag tctgtgtgac gggtctctca acccttccag
    61741 tagctcacac ctataatatc tggggtcaaa taatctgttt gctcttgatt cagatcggtg
    61801 gtctagggct catgaccttt attggggttt tctatatcca gagcaagcaa aagcttagtc
    61861 ttcgtagccg tgcaactatt caggatagtt ttagttatgg agaaactcga tctttgagaa
    61921 agtttgtcta ttctattttt ctcacgacct ttttggttga gagcttggga gctattttgc
    61981 ttagttttcg ccttattcct caacttggct ggggacgtgg tctttttagt tccatttttc
    62041 tagcgatctc agccttctgt aatgccggtt ttgataattt agggagcacc agtttatttg
    62101 cttttcagac cgatttactg gtcaatctgg tgattgcagg cttgattatt acaggcggcc
    62161 ttggttttat ggtctggttt gatttggctg gtcatgtagg aagaaagaaa aaaggacgtc
    62221 tgcactttca tacgaagctt gtactattat tgactatagg tttgttgtta tttggaacag
    62281 caactactct ctttcttgag tggaacaatg ctggaacgat tggcaatctc cctgttgccg
    62341 ataaggtttt agttagcttt tttcaaacag tgacgatgcg aacagctggc ttttctacga
    62401 tagattatac tcaggctcat cctgtgactc ttttgattta tatcttacag atgtttctag
    62461 gtggggcacc tggaggaaca gctgggggac tcaagattac gacatttttt gtcctcttgg
    62521 tctttgcacg aagtgagctt ctaggcttgc ctcatgccaa tgttgcgaga cgaacgatcg
    62581 cgccgcgaac ggttcaaaaa tcctttagtg tctttattat ctttttgatg agcttcttga
    62641 taggattgat tctgctaggg ataacagcca aaggcaatcc tccctttatc cacctcgtat
    62701 ttgaaaccat ttcagctctt agtacagttg gtgtaacggc aaatctgact cctgaccttg
    62761 ggaaattggc tctcagtgtt atcatgccac ttatgtttat gggacgaatt ggtcccttga
    62821 ccttgtttgt tagcttggca gattaccatc cagaaaagaa agatatgatt cactatatga
    62881 aagcagatat tagtattggt taagaaagga aagagcatgt cagatcgtac gattggaatt
    62941 ttgggcttgg gaatttttgg gagcagtgtc ctagctgccc tagccaagca ggatatgaat
    63001 attatcgcta ttgatgacca cgcagagcgc atcaatcagt ttgagccagt tttggcgcgt
    63061 ggagtgattg gtgacatcac agatgaagaa ttattgagat cagcagggat tgatacctgc
    63121 gataccgttg tagtcgcgac aggtgaaaat ctggagtcga gtgtgcttgc ggttatgcac
    63181 tgtaagagtt tgggggtacc gactgttatt gctaaggtca aaagtcagac cgctaagaaa
    63241 gtgctagaaa agattggagc tgactcggtt atctcgccag agtatgaaat ggggcagtct
    63301 ctagcacaga ccattctttt ccataatagt gttgatgtct ttcagttgga taaaaatgtg
    63361 tctatcgtgg agatgaaaat tcctcagtct tgggcaggtc aaagtctgag taaattagac
    63421 ctccgtggca aatacaatct gaatattttg ggtttccgag agcaggaaaa ttccccattg
    63481 gatgttgaat ttggaccaga tgacctcttg aaagcagata cctatatttt ggcagtcatc
    63541 aacaaccagt atttggatac cctagtagca ttgaattcgt aaagagggat gacccctctt
    63601 ttttgatgcc taagatggca aatagagaca gaagcccctt gtcttctagt aaaagttctt
    63661 caaaggctgg actttatggt aaaatagaaa gaagtgacaa gagagagtaa tactcaatga
    63721 aaatcaaaga tcaaactagg aaactagcta cgggctgctc aaaacactgt tttgaggttg
    63781 cagatagaac tgacgaagtc agtaacatct atacggcaag gcgacgttga cgcggtttga
    63841 agagattttc gaagagtata agaaaaaatc agtcccctaa aggagtagat tatgaagtta
    63901 ttgtctatcg caatttctag ctataatgca gcagcctatc ttcattactg tgtggagtcg
    63961 ctagtgattg gtggtgagca agttgggatt ttgattatca atgacgggtc tcaggatcag
    64021 actcaggaaa tcgctgagtg tttagctagc aagtatccta atatcgttag agccatctat
    64081 caggaaaata aatgccatgg cggtgcggtc aatcgtggct tggtagaggc ttctgggcgc
    64141 tattttaaag tagttgacag tgatgactgg gtggatcctc gtgcctactt gaaaattctt
    64201 gaaaccttgc aggaacttga gagcaaaggt caagaggtgg atgtctttgt gaccaatttt
    64261 gtctatgaaa aggaagggca gtctcgtaag aagagtatga gttacgattc agtcttgcct
    64321 gttcggcaga tttttggctg ggaccaggtc ggaaatttct ccaaaggcca gtataccatg
    64381 atgcactcgc tgatttatcg gacagatttg ttgcgtgcta gccagttcta actgcctgaa
    64441 catacttttt atgtcgataa tctctttgtc tttacgcccc ttcagcaggt caagaccatg
    64501 tactatctgc ctgtcgattt ctatcgttat ttgattgggc gtgaggacca gtctgtcaat
    64561 gagcaagtga tgattaagtg cattgaccag caactcaagg tcaatcgact cttgatagac
    64621 caacttgatt tgtcccaagt gagtcatccc aaaatgcgag aatatctgct gaatcatatt
    64681 gaactcacga cggtgatttc cagtaccctg ctcaaccgat ctggaacagc ggagcatctg
    64741 gcaaaaaaac gccaattgtg gacctatatt cagcagaaaa atccagaagt ctttcaggct
    64801 attcgtaaga ccatgttgag ccgtttgacc aaacattctg tcttgccaga tcgcaaactg
    64861 tccaatgtcg tctatcaaat caccaaatct gtttatggat ttaattaata taagtgtttt
    64921 ataagaggga tttaagaaaa attttaactt tttcttagtc ctttttaatt tcaggagatt
    64981 atactagagt catcaaataa agaaagactc taaggagaat cctatgaaat tcaatccaaa
    65041 tcaaagatat actcgttggt ctattcgccg tctcagtgtc ggtgttgcct cagttgttgt
    65101 ggctagtggc ttctttgtcc tagttggtca gccaagttct gtacgtgccg atgggctcaa
    65161 tccaacccca ggtcaagtct tacctgaaga gacatcggga acgaaagagg gtgacttatc
    65221 agaaaaacca ggagacaccg ttctcactca agcgaaacct gagggcgtta ctggaaatac
    65281 gaattcactt ccgacaccta cagaaagaac tgaagtgagc gaggaaacaa gcccttctag
    65341 tctggataca ctttttgaaa aagatgaaga agctcaaaaa aatccagagc taacagatgt
    65401 cttaaaagaa actgtagata cagctgatgt ggatgggaca caagcaagtc cagcagaaac
    65461 tactcctgaa caagtaaaag gtggagtgaa agaaaataca aaagacagca tcgatgttcc
    65521 tgctgcttat cttgaaaaag ctgaagggaa aggtcctttc actgccggtg taaaccaagt
    65581 aattccttat gaactattcg ctggtgatgg tatgttaact cgtctattac taaaagcttc
    65641 ggataatgct ccttggtctg acaatggtac tgctaaaaat cctgctttac ctcctcttga
    65701 aggattaaca aaagggaaat acttctatga agtagactta aatggcaata ctgttggtaa
    65761 acaaggtcaa gctttaattg atcaacttcg cgctaatggt actcaaactt ataaagctac
    65821 tgttaaagtt tacggaaata aagacggtaa agctgacttg actaatctag ttgctactaa
    65881 aaatgtagac atcaacatca atggattagt tgctaaagaa acagttcaaa aagccgttgc
    65941 agacaacgtt aaagacagta tcgatgttcc agcagcctac ctagaaaaag ccaagggtga
    66001 aggtccattc acagcaggtg tcaaccatgt gattccatac gaactcttcg caggtgatgg
    66061 catgttgact cgtctcttgc t
//
LOCUS       DAVFER010000005        63218 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1105170250
            SAMEA2167659-rid19724873.denovo.005, whole genome shotgun sequence.
ACCESSION   DAVFER010000005 DAVFER010000000
VERSION     DAVFER010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2167659
            Sequence Read Archive: ERR388902
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 63218)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 63218)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928716.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928716.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 04:07:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,118
            CDSs (total)                      :: 2,073
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 120
            CDSs (without protein)            :: 120
            Pseudo Genes (ambiguous residues) :: 0 of 120
            Pseudo Genes (frameshifted)       :: 67 of 120
            Pseudo Genes (incomplete)         :: 47 of 120
            Pseudo Genes (internal stop)      :: 34 of 120
            Pseudo Genes (multiple problems)  :: 23 of 120
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..63218
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2167659-rid19724873.denovo.005"
                     /strain="1105170250"
                     /db_xref="taxon:1313"
     gene            complement(417..1907)
                     /gene="lysS"
                     /locus_tag="VU534_000318"
     CDS             complement(417..1907)
                     /gene="lysS"
                     /locus_tag="VU534_000318"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003055423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HEU1512967.1"
                     /translation="MSTEHMEELNDQQIVRREKMAALREQGIDPFGKRFERTANSQEL
                     KDKYANLDKEQLHDKNETATIAGRLITKRGKGKVGFAHLQDREGQIQIYVRKDAVGEE
                     NYEIFKKADLGDFLGVEGEVMRTDMGELSIKATHITHLSKALRPLPEKFHGLTDVETI
                     YRKRYLDLISNRESFERFVTRSKIISEIRRYLDQKGFLEVETPVLHNEAGGAAARPFI
                     THHNAQNIDMVLRIATELHLKRLIVGGMERVYEIGRIFRNEGMDATHNPEFTSIEVYQ
                     AYADFQDIMDLTEGIIQHAAKSVKGDGPVNYQGTEIKINEPFKRVHMVDAIREITGVD
                     FWQDMTLEEAKAIAAEKKVPVEKHYTEVGHIINAFFEEFVEETLIQPTFVYGHPVAVS
                     PLAKKNPEDQRFTDRFELFIMTKEYGNAFTELNDPIDQLSRFEAQAKAKELGDDEATG
                     IDYDYIEALEYGMPPTGGLGIGIDRLCMLLTDTTTIRDVLLFPTMK"
     gene            complement(2035..2181)
                     /locus_tag="VU534_000319"
     CDS             complement(2035..2181)
                     /locus_tag="VU534_000319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate oxidase"
                     /protein_id="HEU1512968.1"
                     /translation="MSYKTSNAEGHVDFINTYDLEPMAQQVIPKAAFGYIASGAGDTF
                     TSFQ"
     gene            2407..3075
                     /locus_tag="VU534_000320"
     CDS             2407..3075
                     /locus_tag="VU534_000320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006531263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEU1512969.1"
                     /translation="MVEQYLPLYQKAFFLTLHIAVWGILGSFLLGLIVSIIRHYRILV
                     LAQVATAYIELSRNTPLLIQLFFLYFGLPRIGIVLSSEVCATLGLVFLGGSYMAESFR
                     SGLEAISQTQQEIGLAIGLTPLQVFYYVVLPQATAVALPSFSANVIFLIKETSVFSAV
                     ALADLMYVAKDLIGLYYETDIALAMLVVAYLIMLLPISLVFSWIERRLRHAGFGNPST
                     LSRK"
     gene            3035..3712
                     /locus_tag="VU534_000321"
     CDS             3035..3712
                     /locus_tag="VU534_000321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001154125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEU1512970.1"
                     /translation="MQDSGIQVLFQGNNLLRILQGLGVTIGISILSVLLSMMFRTVMG
                     IIMTSHSRIIRFLTRLYLEFIRIMPQLVLLFIVYFGLARNFNINISGETSAIIVFTLW
                     GTAEMGDLVRGAITSLPKHQFESGQALGLTNVQLYYHIIIPQVLRRLLPQAINLVTRM
                     IKTTSLVVLIGVVEVTKVGQQIIDSNRLTIPTASFWIYGTILILYFAVCYPISKLSTH
                     LEKHWRN"
     gene            3713..4471
                     /locus_tag="VU534_000322"
     CDS             3713..4471
                     /locus_tag="VU534_000322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEU1512971.1"
                     /translation="MSETILEIKELKKSFGDNPILQGLSLEIKKGEVVVILGPSGCGK
                     STLLRCLNGLESIQGGDILLDGQSIVENKKDFHLVRQKIGMVFQSYELFPHLDVLQNL
                     ILGPIKAQGRDKKEVTEEALQLLERVGLLDKQHSFARQLSGGQKQRVAIVRALLMHPE
                     IILFDEVTASLDPEMVREVLELINDLAQEGRTMILVTHEMQFAQAITDRIIFLDQGKI
                     AEEGTAQAFFTNPQTKRAQEFLNVFDFSQFGSYL"
     gene            4483..5354
                     /locus_tag="VU534_000323"
                     /pseudo
     CDS             4483..5354
                     /locus_tag="VU534_000323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000765259.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine ABC transporter substrate-binding
                     protein"
     gene            complement(5441..6088)
                     /locus_tag="VU534_000324"
     CDS             complement(5441..6088)
                     /locus_tag="VU534_000324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU1512972.1"
                     /translation="MNEIITLKNIELKLKKTCVFQNLNFSCKQGEIIGITGANGSGKS
                     VLFKLIAGLYSPSYGEVLINGENIVPERKIPANLGALIEEPGFINYYSGFKNLQYLAS
                     IRGVVGNQEINDTLKIVGLYEQKDQKVKTYSLGMRKKLGIAQAIMENPSILLLDEPMN
                     ALDKSSVENMRTLFRKLSSEKGTTILIASHSEEDIRILCDKVYAIEDKVCTLCSD"
     gene            complement(6085..6783)
                     /locus_tag="VU534_000325"
     CDS             complement(6085..6783)
                     /locus_tag="VU534_000325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1512973.1"
                     /translation="MGKLSSHMWRLNQIIYTKYFWGYVLFWILICLGLWYWLEGNDRL
                     VIEILKGPNLSQNSFLVLSIWLLHWFIIHTFFLAVVYRRRASDFFMEVIRFSSIKLWI
                     RYQIWTCFLYGLILIMVKVLVIQFMLQLPNWDIGVLFIVDSLNACVLVLFCFMLYALG
                     ANVQMNFACVSFFLLMIVFGGLFVGNRTNYLFYILNRGNGDIGRDLFLQLLFLVFLFQ
                     SIFYFTRQKRRFIE"
     gene            complement(6793..7545)
                     /locus_tag="VU534_000326"
     CDS             complement(6793..7545)
                     /locus_tag="VU534_000326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1512974.1"
                     /translation="MKQFVQFYKKDFLAVLVYFILLLSCVLSSTVYLLRCRQYSIHPN
                     VLEWILVLLQDMTTGVYCFPFTYILFFFYLMNNYFNRLECRIRLKSIKHFTSFSFKLA
                     ALSTGIWTATLFLLIFLIAFSNGFSFSLEIKEVDFLREFYGISIANNASFFIGFFFSY
                     IAYYFFLSLLTISSFSWFKKSNMSLVFLFTFLFVESLFWIYQLDNGIIGLLPIFQYMV
                     NSNPYALIYWLTLLSIIIPLTVFSVHRNWRRV"
     gene            complement(7545..8309)
                     /locus_tag="VU534_000327"
     CDS             complement(7545..8309)
                     /locus_tag="VU534_000327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000394067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1512975.1"
                     /translation="MEFFICNLVRVVQSPRFYMSLFLTLLCMSLGNFLAFNGIYKIEG
                     LSIFFAASSIRGFSPISLVAALICTLPYSSQIIEDAESHFLTAQLCRISKKKYLAIVG
                     STVIISSFLVFFLPYLLLLGINLLVTPYQEIYIGDYSGALKELFDSNQFLYSLVTTLW
                     YGVWGAVFSIFGLASALLVKKKIGAIFIPVAYMMVGGIFWAILGLSYLEPVTTLALGY
                     QKDISLSLVSAHLAFILFVSCLVVYGTFFLHSEDYV"
     gene            complement(8405..8808)
                     /locus_tag="VU534_000328"
                     /pseudo
     CDS             complement(8405..8808)
                     /locus_tag="VU534_000328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000829085.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(8988..9620)
                     /locus_tag="VU534_000329"
     CDS             complement(8988..9620)
                     /locus_tag="VU534_000329"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HEU1512976.1"
                     /translation="MTLAKDIASHLLKIQAVYLKPEEPFTWASGIKSPIYTDNRVTLA
                     YPETRTLIENGFVEAIKEAFPEVEVIAGTATAGIPHGAIIADKMDLPFAYIRSKPKDH
                     GAGNQIEGRVAQGQKMVVVEDLISTGGSVLEAVAAAKREGADVLGVVAIFSYQLPKAD
                     KNFADAGVKLVTLSNYSELIHLAQEEGYITPEGLDLLKRFKEDQENWQEG"
     gene            complement(9654..10355)
                     /gene="pyrF"
                     /locus_tag="VU534_000330"
     CDS             complement(9654..10355)
                     /gene="pyrF"
                     /locus_tag="VU534_000330"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001206708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HEU1512977.1"
                     /translation="MREHRPIIALDFPSFEAVKEFLALFPAEESLYLKVGMELYYAAG
                     PEIVSYLKGLGHSVFLDLKLHDIPNTVKSAMKILSQLGVDMTNVHAAGGVEMMKAARE
                     GLGSQAKLIAVTQLTSTSEAQMQEFQNIQTSLQESVIHYAKKTAEAGLDGVVCSAQEV
                     QVIKQATNPDFICLTPGIRPAGVAVGDQKRVMTPADAYQIGSDYIVVGRPITQAEDPV
                     AAYHAIKDEWTQDWN"
     gene            10674..10766
                     /locus_tag="VU534_000331"
                     /pseudo
     CDS             10674..10766
                     /locus_tag="VU534_000331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011516271.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            complement(11101..11814)
                     /locus_tag="VU534_000332"
     CDS             complement(11101..11814)
                     /locus_tag="VU534_000332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU1512978.1"
                     /translation="MLKRFLALVWLRCQIILSNKSILLQVLVPFAFTYFYKYLMETQG
                     KVNDQQALVLLMMCLPFSFSLAVGSPITIILSEEKEKYNLQTLLLSGVKGSEYILSTM
                     FLPFLLTFVIMGTTPLILGVTIVHTFNYITIVLLTSLSIILFYLLIGLTAKSQVVAQV
                     ISLPAMILVAFLPMLSGLDKTVAKITDYSFMGLFTKFFTKWEEFSWNKTLIPNLTLLI
                     WIVLLLTLITITIRKKKIS"
     gene            complement(11807..12646)
                     /locus_tag="VU534_000333"
                     /pseudo
     CDS             complement(11807..12646)
                     /locus_tag="VU534_000333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000061739.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            complement(12850..13861)
                     /locus_tag="VU534_000334"
                     /pseudo
     CDS             complement(12850..13861)
                     /locus_tag="VU534_000334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001817174.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ThiF family adenylyltransferase"
     gene            complement(14204..14840)
                     /locus_tag="VU534_000335"
                     /pseudo
     CDS             complement(14204..14840)
                     /locus_tag="VU534_000335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001824573.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase M50 family protein"
     gene            complement(15599..16798)
                     /gene="divIB"
                     /locus_tag="VU534_000336"
     CDS             complement(15599..16798)
                     /gene="divIB"
                     /locus_tag="VU534_000336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DivIB"
                     /protein_id="HEU1512979.1"
                     /translation="MSKDKKNEDKETLEELKELSEWQKRNQEYLKKKAEEEAALAEEK
                     EKERQARMGEESEKSEDKQDQESETDQEDSESAKEESEEKVASSEADKEKEEKEEPES
                     KEKEEQDKKLAKKATKEKPAKAKIPGIHILRAFTILFPSLLLLFVSAYLLSPYATMKD
                     IRVEGTVQTTADDIRQASGIQDSDYTINLLLDKAKYEKQIKSNYWVESAQLVYQFPTK
                     FTIKVKEYDIVAYYISGENHYPILSSGQLETSSVSLNSLPETYLSVLFNDSEQIKVFV
                     SELAQISPELKAAIQKVELAPSKVTSDLIRLTMNDSDEVLVPLSEMSKKLPYYSKIKP
                     QLSEPSVVDMEAGIYSYTVADKLIMEAEEKAKQEAKEAEKKQEEEQKKQEEESNRNQT
                     TQRSSRR"
     gene            complement(16808..17866)
                     /locus_tag="VU534_000337"
     CDS             complement(16808..17866)
                     /locus_tag="VU534_000337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine--N-acetylmuramyl-
                     (pentapeptide) pyrophosphoryl-undecaprenol
                     N-acetylglucosamine transferase"
                     /protein_id="HEU1512980.1"
                     /translation="MKKIVFTGGGTVGHVTLNLLLMPKFIEDGWEVHYIGDKCGIEHQ
                     EILKSGLDVTFHSIATGKLRRYFSWQNMLDVFKVGWGIVQSLFIMLRLRPQTLFSKGG
                     FVSVPPVIAARVSGVPVFIHESDLSMGLANKIAYKFATKMYSTFEQASSLAKVEHVGA
                     VTKVSDKNTPEPDELVDIQTHFNPKLPTVLFVGGSAGARVFNQLVTDHKKELTERYNI
                     INLTGDSSLNELRQNLFRVDYVTDLYQPLMELADIVVTRGGANTIFELLAIAKLHVIV
                     PLGREASRGDQIENAAYFVKKGYAEDLQESDLTLDSLEEKLSHLLSHKEDYQAKMKAS
                     KELKSLADFYQLLKKDLS"
     gene            complement(17868..19220)
                     /locus_tag="VU534_000338"
     CDS             complement(17868..19220)
                     /locus_tag="VU534_000338"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HEU1512981.1"
                     /translation="MKVIDQFKNKKVLVLGLAKSGESAARLLDKLGAIVTVNDGKPFE
                     DNPAAQSLLEEGIKVITGGHPLELLDEEFALMVKNPGIPYNNPMIEKALAKGIPVLTE
                     VELAYLISEAPIIGITGSNGKTTTTTMIGEVLTAAGQHGLLSGNIGYPASQVAQIASD
                     KDTLVMELSSFQLMGVQEFHPEIAVITNLMPTHIDYHGSFSEYVAAKWNIQNKMTAAD
                     FLVLNFNQDLAKDLTSKTEATVVPFSTLEKVDGAYLEDGQLYFRGEVVMAANEIGVPG
                     SHNVENALATIAVAKLRDVDNQTIKETLSAFGGVKHRLQFVDDIKGVKFYNDSKSTNI
                     LATQKALSGFDNSKVVLIAGGLDRGNEFDELVPDITGLKKMVILGQSAERVKRAADKA
                     GVAYVEATDIADATRKAYELATQGDVVLLSPANASWDMYANFEVRGDLFIDTVAELKE
                     "
     gene            complement(19324..19965)
                     /locus_tag="VU534_000339"
     CDS             complement(19324..19965)
                     /locus_tag="VU534_000339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU1512982.1"
                     /translation="MIELKNISKKFGSRQLFSDMNLHFEGGKIYALIGTSGCGKTTLL
                     NMIGRLEPYDKGQIIYDGTSLKDIKPSVFFRDYLGYLFQDFGLIESQTVKENLNLGLV
                     GKKLKEKEKISLMKQALNRVNLSYLDLKQPIFELSGGEAQRVALAKIILKDPPLILAD
                     EPTASLDPKNSEELLSILESLKNPNRTIIIATHNPLIWEQVDQVIRVTDLSHR"
     gene            complement(19967..21988)
                     /locus_tag="VU534_000340"
     CDS             complement(19967..21988)
                     /locus_tag="VU534_000340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000732428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HEU1512983.1"
                     /translation="MKKLFILLSTFFLSFFLAWIIVLRAPQYLYASYDSVSLLRVKKD
                     TQEPTREVFEQELENFANSEQSLIARRIVEPSKDGTTHFTYATYGQGTLPKEFQEASQ
                     ESRERSDPLNSYLLLSGSLTKEKLADKLGDLGYKASADRKIPPYFLAFRILLNPLILI
                     SLAIFGLSFFALVIITRIKEMRAAGIKLFSGQTLLSIMGHSLSTDIKWLLLSALLSFL
                     GGGVVLFSQGLFYPILLATYGFGISFYLLFLLAISILLMLLYLMSLSYKALVPVIKGR
                     LPLKRLMALTLLCQLVAVFTVGYAVKTGLTSYQRLKELEISKQAWQDRADYYQISFGL
                     GDRGKDTENQSKWYAFAKEAIEEEQALYVKDNLLHFANPQGKNEQGETLDTYSPDANT
                     LYVSPSYLDKEKVVVDAETKQKLAHLQKGEFILLLPEHLRSREAELKKVFEERLSYYG
                     KSGEEASAPLDYEMKAHVSYLSMGEKRFVYNNGENPVSTQYLTDPILVVFTPTSTGDS
                     FISLSSWSINAGKQLFIKGYESGLELLKKAGIYEQVSYLKEGRSVYLTRYNEVQTETA
                     TLILGAIVGIASSLLLFYSVNLLYFEQFRRDILIKRISGLRFFETHAQYMVSQFASFV
                     FGASLFILSSRDLVIGLLTLLVFLASAVLTLYRQAQKESRVSMTIMKGK"
     gene            complement(22059..22358)
                     /locus_tag="VU534_000341"
                     /pseudo
     CDS             complement(22059..22358)
                     /locus_tag="VU534_000341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397967.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
     gene            complement(22722..22976)
                     /locus_tag="VU534_000342"
     CDS             complement(22722..22976)
                     /locus_tag="VU534_000342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3165 family protein"
                     /protein_id="HEU1512984.1"
                     /translation="MVYLVLGILLLLLYVFATPESIKGTVNIVAMVCILVALLILLVL
                     SFLKIFQLPTEIFLAIAMLILAYFSVRDITLMPVKKSKRR"
     gene            complement(22996..24837)
                     /gene="typA"
                     /locus_tag="VU534_000343"
     CDS             complement(22996..24837)
                     /gene="typA"
                     /locus_tag="VU534_000343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003078415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HEU1512985.1"
                     /translation="MTKLREDIRNIAIIAHVDHGKTTLVDELLKQSETLDARTELAER
                     AMDSNDIEKERGITILAKNTAVAYNGTRINIMDTPGHADFGGEVERIMKMVDGVVLVV
                     DAYEGTMPQTRFVLKKALEQDLVPIVVVNKIDKPSARPAEVVDEVLELFIELGADDDQ
                     LDFPVVYASAINGTSSLSDDPADQEATMAPIFDTIIDHIPAPVDNSDEPLQFQVSLLD
                     YNDFVGRIGIGRVFRGTVKVGDQVTLSKLDGTTKNFRVTKLFGFFGLERREIQEAKAG
                     DLIAVSGMEDIFVGETITPTDAVEALPILHIDEPTLQMTFLVNNSPFAGKEGKWVTSR
                     KVEERLQAELQTDVSLRVDPTDSPDKWTVSGRGELHLSILIETMRREGYELQVSRPEV
                     IVKEIDGIKCEPFERVQIDTPEEYQGSVIQSLSERKGEMLDMISTGNGQTRLVFLVPA
                     RGLIGYSTEFLSMTRGYGIMNHTFDQYLPLIPGEIGGRHRGALVSIDAGKATTYSIMS
                     IEERGTIFVNPGTEVYEGMIIGENSRENDLTVNITKAKQMTNVRSATKDQTAVIKTPR
                     ILTLEESLEFLNDDEYMEVTPESIRLRKQILNKAEREKANKKKKSAE"
     gene            24999..25724
                     /locus_tag="VU534_000344"
     CDS             24999..25724
                     /locus_tag="VU534_000344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001235004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA pseudouridine(516) synthase"
                     /protein_id="HEU1512986.1"
                     /translation="MRLDNLLAQEKISRKAMKQALLRGEILVDGCPARSLAQNIDTGL
                     QELLFQDRIIQGYEHTYLMLHKPAGAVTANKDKELPTVMDLLPSNIQSDKLYAVGRLD
                     RDTTGLLLLTDNGPLGFQLLHPQYHVDKTYQVEVNGLLTPDHIQTFQKGIVFLDDTVC
                     KPAKLEILSASPSLSQASITISEGKFHQIKKMFLSVGVKVTSLKRIQFGDFTLNPDLA
                     EGNYRPLNQKELQIIKNYLEMSR"
     gene            complement(25764..25991)
                     /locus_tag="VU534_000345"
     CDS             complement(25764..25991)
                     /locus_tag="VU534_000345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000660075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1512987.1"
                     /translation="MKEKKKNPLFVGILSIILGLLFPIVGLILGIIGLVLAISYQKES
                     QLDYKIEKILNILGIVISVVNWIVAIALIFR"
     gene            complement(26080..26460)
                     /locus_tag="VU534_000346"
     CDS             complement(26080..26460)
                     /locus_tag="VU534_000346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEU1512988.1"
                     /translation="MVTWILWALILAMLAWMGFNYLRIRRAAKIVDNEEFEALIRTGQ
                     LIDLRDPAEFHRKHILGARNIPSSQLKTSLAALRKDKPVLLYENQRAQRVTNAALYLK
                     KQGFSEIYILSYGLDSWKGKVKTS"
     gene            complement(26460..26729)
                     /locus_tag="VU534_000347"
     CDS             complement(26460..26729)
                     /locus_tag="VU534_000347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgQ family protein"
                     /protein_id="HEU1512989.1"
                     /translation="MSLFLKKTQNFARMSLMKTFYDVQQFLKRFGIIVYMGKRLYDIE
                     LMKLELSRIYDAGLMDKLDYLEAEAVLRREHKVELDYIEKNGEKN"
     gene            26793..27701
                     /locus_tag="VU534_000348"
     CDS             26793..27701
                     /locus_tag="VU534_000348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEU1512990.1"
                     /translation="MRIQQLHYIIKIVETGSMNEAAKQLFITQPSLSNAVRDLENEMG
                     IEIFIRNPKGITLTRDGMEFLSYARQVVEQTQLLEERYKNPVAHRELFSVSSQHYAFV
                     VNAFVSLLKKSDMEKYELFLRETRTWEIIDDVKNFRSEVGVLFLNSYNRDVLTKMLDD
                     NHLLAHHLFTAQPHIFVSKTNPLAKKDKVKLSDLENFPYLSYDQGTHNSFYFSEEILS
                     QEHHKKSIVVSDRATLFNLLIGLDGYTIATGILNSNLNGDNIVSIPLDIDDPIELVYI
                     QHEKTSLSKMGERFIDYLLEEVQFDS"
     gene            complement(27755..28510)
                     /locus_tag="VU534_000349"
     CDS             complement(27755..28510)
                     /locus_tag="VU534_000349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HEU1512991.1"
                     /translation="MPTILITGASGGLAQEMVKLLPNDQLILLGRNKEKLAQLYGNYS
                     HAELIEIDITDDSALEALVTDLYLRYGKIDVLINNAGYGIFEGFDQIADKDIHQMFEV
                     NTFALMNLSRHLAARMKESSKGHIINIVSMAGLIATGKSSLYSATKFAAIGFSNALRL
                     ELMPYGVYVTTVNPGPIRTGFFDQADPDGTYLKSVDRFLLEPDAVAKKIVKIIGKNKR
                     ELNLPILLNLAHKFYTLFPKLADKLAGETFNYK"
     gene            complement(28531..29460)
                     /locus_tag="VU534_000350"
     CDS             complement(28531..29460)
                     /locus_tag="VU534_000350"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000354350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HEU1512992.1"
                     /translation="MDIQFLGTGAGQPSKARNVSSLALKLLDEINEVWLFDCGEGTQN
                     RILETTIRPRKVSKIFITHLHGDHIFGLPGFLSSRAFQANEEQTDLEIYGPQGIKSFV
                     LTSLRVSGSRLPYRIHFHEFDQDSLGKILETDKFTVYAEELDHTIFCVGYRVMQKDLE
                     GTLDAEKLKAAGVPFGPLFGKIKNGQDLVLEDGTEIKAADYISAPRPGKIITILGDTR
                     KTGASVRLAVNADVLVHESTYGKGDEKIARNHGHSTNMQAAQVAVEAGAKRLLLNHIS
                     ARFLSKDISKLKKDAATIFENVHVVKDLEEVEI"
     gene            complement(29475..30098)
                     /locus_tag="VU534_000351"
     CDS             complement(29475..30098)
                     /locus_tag="VU534_000351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine beta-lyase"
                     /protein_id="HEU1512993.1"
                     /translation="MTDIKTLALKYGGYTSLDKVYLDQLLAGKTDQEQLTLITPPPSV
                     VNAYFAELYQKKSPQAATDYFAELSQELNLYNTEPSFTLENKPFIRLNLSGKSFGFCY
                     ESDGLGRIFFENEEKISDDLLFEIAQIFPHQLVFEESGKIYMKPVEDEEVISLESLTA
                     LTDLERLADGRKRLKGYSQEDLLQEAAAFSGKRYFRSENRTAMLYID"
     gene            complement(30091..31329)
                     /gene="hflX"
                     /locus_tag="VU534_000352"
     CDS             complement(30091..31329)
                     /gene="hflX"
                     /locus_tag="VU534_000352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000573186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HEU1512994.1"
                     /translation="MIETEKKEERVLLIGVELQGMDSFDLSMEELASLAKTAGAVVVD
                     SYRQKREKYDSKTFVGSGKLEEIALMVDAEEITTVIVNNRLTPRQNVNLEEVLGVKVI
                     DRMQLILDIFAMRARSHEGKLQVHLAQLKYLLPRLVGQGIMLSRQAGGIGSRGPGESQ
                     LELNRRSVRNQITDIERQLKVVEKNRATVREKRLESSTFKIGLIGYTNAGKSTIMNIL
                     TSKTQYEADELFATLDATTKSIHLGGNLQVTLTDTVGFIQDLPTELVSSFKSTLEESK
                     HVDLLVHVIDASNPYHEEHEKTVLSIMKDLDMEDIPHLTLYNKADLVEDFTPTQTPYT
                     LISAKSEDSRENLQALLLDKIKEIFEAFTLRVPFSKSYKIHDLESVAILEERDYQEDG
                     EVITGYISEKNKWRLEEFYD"
     gene            complement(31322..32206)
                     /gene="miaA"
                     /locus_tag="VU534_000353"
     CDS             complement(31322..32206)
                     /gene="miaA"
                     /locus_tag="VU534_000353"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HEU1512995.1"
                     /translation="MKTKIIVIVGPTAVGKTALAIEVAKRFNGEVVSGDSQQVYRGLD
                     IGTAKASPEEQAAVPHHLIDVREITESYSAFDFVSEAKMTIEGIHNRGKLAIIAGGTG
                     LYIQSLLEGYHLGGETPHEEILAYRASLEPYSDEELAHLVDQAGLEIPQFNRRRAMRA
                     LEIAHFGQDLENQETLYEPLIICLDDERSQLYERINHRVDLMFEAGLLDEAKWLFDHS
                     PNVQAAKGIGYKELFPYFRGEQTLEEASESLKQATRRFAKRQLTWFRNRMQVTFYQIG
                     ESGVQDRILSQIEEFLDD"
     gene            32327..32497
                     /locus_tag="VU534_000354"
     CDS             32327..32497
                     /locus_tag="VU534_000354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001051775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3042 family protein"
                     /protein_id="HEU1512996.1"
                     /translation="MAKGFAKGLVTGVAGTVAAVAGAVYAFKKKVIEPEEQKAAFIEE
                     NRKKAARRRVSR"
     gene            complement(32545..33384)
                     /locus_tag="VU534_000355"
     CDS             complement(32545..33384)
                     /locus_tag="VU534_000355"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003011065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HEU1512997.1"
                     /translation="MTKADTIFKENIERILKEGVFSEQARPKYKDGTVANSKYVTGAF
                     SEYDLSKGEFPITTLRPIAIKSAIKEVLWIYQDQSNSLEVLNDKYNVHYWNDWEVGDT
                     GTIGERYGAVVKKHDIINKLLKQLETNPWNRRNIISLWDYQAFEETDGLLPCAFQTMF
                     DVRRVDGEIYLDATLTQRSNDMLVAHHINAMQYVALQMMIAKHFGWKVGKFFYFINNL
                     HIYDNQFEQAQELLRREPSNCQPRLVLNVPDGTNFFDIKAEDFELVDYDPVKPQLKFD
                     LAI"
     gene            complement(33481..34440)
                     /locus_tag="VU534_000356"
     CDS             complement(33481..34440)
                     /locus_tag="VU534_000356"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002919069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HEU1512998.1"
                     /translation="MSQKIIGIDLGGTSIKFAILTTAGEIQGKWSIKTNILDEGSHIV
                     DDMIESIQHRLDLLGLAAADFQGIGMGSPGVVDRDKGTVIGAYNLNWKTLQPIKQKIE
                     KALGIPFFIDNDANVAALGERWMGAGDNQPDVVFMTLGTGVGGGIVAEGKLLHGVAGA
                     AGELGHITVDFDQPISCTCGKKGCLETVASATGIVNLTRRYADEYEGDAALKRLIDNG
                     EEVTAKTVFDLAKEGDDLALIVYRNFSRYLGIACANIGSILNPSTIVIGGGVSAAGEF
                     LLQGVQKVYDENSFPQVRTSTKLALATLGNDAGVIGAASLVLQ"
     gene            complement(34567..35565)
                     /locus_tag="VU534_000357"
     CDS             complement(34567..35565)
                     /locus_tag="VU534_000357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HEU1512999.1"
                     /translation="MNKRLFSKMSLVTLPILALFSQSVLAEENIHFSSCKEAWANGYS
                     DIHEGEPGYSAKLDRDHDGVACELKNAPKGAFKAKQSTAIQINTSSATTSGWVKQDGA
                     WYYFDGNGNLVKNAWQGSYYLKADGKMAQSEWIYDSSYQAWYYLKSDGSYAKNAWQGA
                     YYLKSNGKMAQGEWVYDSSYQAWYYLKSDGSYARNAWQGNYYLKSDGKMAKGEWVYDA
                     TYQAWYYLTSDGSYAYSTWQGNYYLKSDGKMAVNEWVDGGRYYVGADGVWKEVQASTA
                     SSSNDSNSEYSAALGKAKSYNSLFHMSKKRMYRQLTSDFDKFSNDAAQYAIDHLDD"
     gene            complement(35615..36232)
                     /locus_tag="VU534_000358"
     CDS             complement(35615..36232)
                     /locus_tag="VU534_000358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000766583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEU1513000.1"
                     /translation="MKLIFLHGLGQSAESWKEVRNLLTDYPSEAIELFPSGVSNYQQA
                     KERVYQHLAQETEPFVLIGLSLGAALTLELSSYDLPNLRALILSGCPLKLAGNILFYL
                     QLLIFKLLPKRVFEKQGADKTLMVGVSEELKTLDLTDIAGTYPYPTLLICGSKDKPNL
                     SSMKALHRLLTDSQFQIIPDGPHVLNKAKPKEFVEKTRSFLELLK"
     gene            complement(36233..37954)
                     /gene="pabB"
                     /locus_tag="VU534_000359"
     CDS             complement(36233..37954)
                     /gene="pabB"
                     /locus_tag="VU534_000359"
                     /EC_number="2.6.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate synthase component I"
                     /protein_id="HEU1513001.1"
                     /translation="MHRKTVIDFRTLGERYTFTQPIKELKTRNVEEVADLLAQVESYQ
                     EQGYYVVGYVSYEAAPAFEEKLAVHKDPLLGEYLLYFTVHDIVETSPIPLTYEDIDLP
                     SNWQEVTSAADYEKAIAQIHHHLRQGDTYQVNYTVQLKQKLNANPFAIYNRMVVEQEA
                     GYNAYVEHDEMTVISMSPELFFEQNDRELTTRPMKGTTQRGVTDQEDLEQASWLEQDP
                     KNRSENMMIVDLLRNDMNRISEVGSEHVERLCQVEQYSTVWQMTSTIKSQLREDVDLV
                     EIFRSLFPCGSITGAPKIATMEIIKDLEPQPRGVYCGTIGLLLPNGRRIFNVAIRTIQ
                     LHKGQAIYGVGGGITWDSTWESEYREVHQKAAVLYRKQARFQLITTGKISQKQLMFEE
                     QHLERLRKASRYFAFPFDAEDLGHKIEEECQDCEANRDYRLRISLSKSGEIEVNRQVL
                     TPLSTSFCQAQVCLQEAALNQSFTYFKTTHRPHLSLGEQEKIYHNKSGELLETSIGNL
                     VLKIAGKLYTPPIRLGILPGIYRQHLLETGQVEEKVLTLADLTQAEAIYGCNAVRGLY
                     ELSLEEN"
     gene            complement(38015..43735)
                     /locus_tag="VU534_000360"
     CDS             complement(38015..43735)
                     /locus_tag="VU534_000360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000472995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEU1513002.1"
                     /translation="MFKKDRFSIRKIKGVVGSVFLGSLLMAPSVVDAATYHYVNKEII
                     SQEAKDLIQTGKPDRNEVVYGLVYQKDQLPQTGTEASVLTAFGLLTVGSLLLIYKRKK
                     IASVFLVGAMGLVVLPSAGAVDPVATLALASREGVVEMEGYRYVGYLSGDILKTLGLD
                     TVLEETSAKPGEVTVVEVETPQSITNQEQARTENQVVETEEAPKEEAPKTEESPKEEP
                     KSEVKPTDDTLPKVEEGKEDSAEPAPVEEVGGEVESKPEEKVAVKPESQPSDKPAEES
                     KVEQAGEPVAPREDEKAPVEPEKQPEAPEEEKAVEETPKQEESTPDTKAEETVEPKEE
                     TVNQSIEQPKVETPAVEKQTEPTEEPKVEQAGEPVAPREDEQAPTAPVEPEKQPEVPE
                     EEKAVEETPKPEDKIKGIGTKEPVDKSELNNQIDKASSVSPTDYSTASYNALGPVLET
                     AKGVYASEPVKQPEVNSETNKLKTAIDALNVDKTELNNTIADAKTKVKEHYSDRSWQN
                     LQTEVTKAEKVAANTDAKQSEVNEAVEKLTATIEKLVELSEKPILTLTSTDKKILERE
                     AVAKYTLENQNKTKIKSITAELKKGEEVINTVVLTDDKVTTETISAAFKNLEYYKEYT
                     LSTTMIYDRGNGEETETLENQNIQLDLKKVELKNIKRTDLIKYENGKETNESLITTIP
                     DDKSNYYLKITSNNQKTTLLAVKNIEETTVNGTPVYKVTAIADNLVSRTADNKFEEEY
                     VHYIEKPKVHEDNVYYNFKELVEAIQNDPSKEYRLGQSMSARNVVPNGKSYITKEFTG
                     KLLSSEGKQFAITELEHPLFNVITNATINNVNFENVEIERSGQDNIASLANTMKGSSV
                     ITNVKITGTLSGRNNVAGFVNNMNDGTRIENVAFFGKLHSTSGNGSHTGGIAGTNYRG
                     IVRKAYVDATITGNKTRASLLVPKVDYGLTLDHLIGTKALLTESVVKGKIDVSNPVEV
                     GAIASKTWPVGTVSNSVSYAKIIRGEELFGSNDVDDSDYASAHIKDLYAVEGYSSGNR
                     SFRKSKTFTKLTKEQADAKVTTFNITADKLESDLSPLAKLNEEKAYSSIQDYNAEYNQ
                     AYKNLEKLIPFYNKDYIVYQGNKLNKEHHLNTKEVLSVTAMNNNEFITNLDEANKIIV
                     HYADGTKDYFNLSSSSEGLSNVKEYTITDLGIKYTPNIVQKDNTTLVNDIKSILESVE
                     LQSQTMYQHLNRLGDYRVNAIKDLYLEESFTDVKENLTNLITKLVQNEEHQLNDSPAA
                     RQMIRDKVEKNKAALLLGLTYLNRYYGVKFGDVNIKELMLFKPDFYGEKVSVLDRLIE
                     IGSKENNIKGSRTFDAFGQVLAKYTKSGNLDAFLNYNRQLFTNIDNMNDWFIDATEDH
                     VYIAERASEVEEIKNSKHRAFDNLKRSHLRNTILPLLNIDKAHLYLISNYNAIAFGSA
                     ERLGKKSLEDIKDIVNKAADGYRNYYDFWYRLASDNVKQRLLRDAVIPIWEGYNAPGG
                     WVEKYGRYNTDKVYTPLREFFGPMDKYYNYNGTGAYAAIYPNSDDIRTDVKYVHLEMV
                     GEYGISVYTHETTHVNDRAIYLGGFGHREGTDAEAYAQGMLQTPVTGSGFDEFGSLGI
                     NMVFKRKNDGNQWYITDPKTLKTREDINRYMKGYNDTLTLLDEIEAESVISQQNKDLN
                     SAWFKKIDREYRDNNKLNQWDKIRNLSQEEKNELNIQSVNDLVDQQLMTNRNPGNGIY
                     KPEAISYNDQSPYVGVRMMTGIYGGNTSKGAPGAVSFKHNAFRLWGYYGYENGFLGYA
                     SNKYKQQSKTDGESVLSDEYIIKKISNNTFNTIEEFKKAYFKEVKDKATKGLTTFEVN
                     GSSVSSYDDLLTLFKEAVKKDAETLKQEANGNKTVSMNNTVKLKEAVYKKLLQQTNSF
                     KTSIFK"
     gene            complement(43757..44320)
                     /locus_tag="VU534_000361"
     CDS             complement(43757..44320)
                     /locus_tag="VU534_000361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001006373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HEU1513003.1"
                     /translation="MNETQIQRETRQVVEDVLEKTNLKQGALFVLGLSSSEVLGGHIG
                     KESSQEIGELIVETILDILGSRGIHLAVQGCEHVNRALVVERQVAEQFGLEIVSVHPT
                     LHAGGSGQLAAFKFMQDPVEVEFIKAHAGLDIGDTAIGMHVKHVQVPIRPILREIGHA
                     HVTALASRPKLIGGARAHYPQDAIRKF"
     gene            complement(44436..46127)
                     /locus_tag="VU534_000362"
     CDS             complement(44436..46127)
                     /locus_tag="VU534_000362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEU1513004.1"
                     /translation="MKRSSLLVRMVISIFLVFLILLALVGTFYYQSSSSAIEATIEGN
                     SQTTISQTSHFIQSYIKKLETTSTGLTQQTDVLAYAENPSQDKVEGIRDLFLTILKSD
                     KDLKTVVLVTKSGQVISTDDSVQMKTSSDMMAEDWYQKAIHQGAMPVLTPARKSDSQW
                     VISVTQELVDAKGANLGVLRLDISYETLEAYLNQLQLGQQGFAFIINENHEFVYHPQH
                     TVYSSSSKMEAMKPYIDTGQGYTPGHKSYVSQEKIAGTDWTVLGVSSLEKLDQVRSQL
                     LWTLLGASVTSLLVCLCLVWFSLKRWIAPLKDLRETMLEIASGAQNLRAKEVGAYELR
                     EVTRQFNAMLDQIDQLMVAIRSQEETTRQYQLQALSSQINPHFLYNTLDTIIWMAEFH
                     DSQRVVQVTKSLATYFRLALNQGKDLICLSDEINHVRQYLFIQKQRYGDKLEYEINEN
                     VAFDNLVLPKLVLQPLVENALYHGIKEKEGQGHIKLSVQKQDSGLVIRIEDDGVGFQD
                     AGDSSQSQLKRGGVGLQNVDQRLKLHFGANYHMKIDSRPQKGTKVEIYINRIETS"
     gene            complement(46124..46861)
                     /locus_tag="VU534_000363"
     CDS             complement(46124..46861)
                     /locus_tag="VU534_000363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU1513005.1"
                     /translation="MTYTILIVEDEYLVRQGLTKLVNVAAYDMEIIGQAENGRQAWEL
                     IQKQVPDIILTDINMPHLNGIQLASLVRETYPQVHLVFLTGYDDFDYALSAVKLGVDD
                     YLLKPFSRQDIEEMLGKIKQKLDKEEKEEQLQDLLTNRFEGNMAQKIQSHLADSQFSL
                     KSLASDLGFSPTYLSSLIKKELGLPFQDYLVRERVKQAKLLLLTTDLKIYEIAEKVGF
                     EDMNYFTQRFKQIAGVTPRQFKKGEDR"
     gene            complement(47129..48241)
                     /gene="msrB"
                     /locus_tag="VU534_000364"
     CDS             complement(47129..48241)
                     /gene="msrB"
                     /locus_tag="VU534_000364"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HEU1513006.1"
                     /translation="MNDKLKIFLLLGVFFLAITGFYVLLIRNAGQTDASQIEKAAVSQ
                     GGKAVKKTEISKDADLHEIYLAGGCFWGVEEYFSRVPGVTDAVSGYANGRGETTKYEL
                     INQTGHAETVHVTYDAKQISLKEILLHYFRIINPTSKNKQGNDVGTQYRTGVYYTDDK
                     DLEVINQVFDEVAKKYDQPLAVEKENLKNFVVAEDYHQDYLKKNPNGYCHINVNQAAY
                     PVIDASKYPKPSDEELKKTLSPEEYAVTQENQTERAFSNRYWDKFESGIYVDIATGEP
                     LFSSKDKFESGCGWPSFTQPISPDVVTYKEDKSYNMTRMEVRSRVGDSHLGHVFTDGP
                     QDKGGLRYCINSLSIRFIPKDQMEEKGYAYLLDYVD"
     gene            complement(48252..48818)
                     /locus_tag="VU534_000365"
     CDS             complement(48252..48818)
                     /locus_tag="VU534_000365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redoxin family protein"
                     /protein_id="HEU1513007.1"
                     /translation="MKKWQTCVLGAGSLLCLTACSGKSVTSEHQTKDEMKTEQTASKT
                     SAAKGKEVADFELMGVDGKTYRLSDYKGKKVYLKFWASWCSICLASLPDTDEIAKEAG
                     DDYVVLTVVSPGHKGEQSEADFKNWYKGLDYKNLPVLVDPSGKLLETYGVRSYPTQAF
                     IDKEGKLVKTHPGFMEKDAILQTLKELA"
     gene            complement(48838..49548)
                     /gene="ccdA2"
                     /locus_tag="VU534_000366"
     CDS             complement(48838..49548)
                     /gene="ccdA2"
                     /locus_tag="VU534_000366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000509848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HEU1513008.1"
                     /translation="MGHIFFFLSVFLAGILSFFSPCILPLLPVYTGVLLDDKDGAQAS
                     SGKFSISVTSLLRTLAFIAGISFIFILLGYGAGFLGDLLYASWFQYLTGAIIILLGLH
                     QMEILHFKGLYKEKRLQLQGQGQNGKGYSQAFLLGLTFSFAWTPCVGPVLGSVLALAA
                     SGGSGAWQGAGLMLVYTLGLALPFLLLALTSSYVLKHFRKLHPYLGILKKVGGFLIIV
                     MGFLVLFGNASILSQLFE"
     gene            complement(49759..50619)
                     /locus_tag="VU534_000367"
     CDS             complement(49759..50619)
                     /locus_tag="VU534_000367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HEU1513009.1"
                     /translation="MKKWWKELIDKPLLKAFLHYYQASDSELTSVAVAYYWLISIFPL
                     LLVVVNILPYFQIPVGEFLGFMKDVLPPSLYEGVEKIAREVLTQPSTGLLSFSVLSAL
                     WSFSKSMNFLQKAFNKAYGVEKSRGLISHQMLSLLVSFGLQLLFAFALFLILFGQMIL
                     ALLAHYWTKDGIIYQALQGLAGPLIYALLFAILVMLYYFLPNLSNRKISYTLPGSAFV
                     LLVILGLLTLFSSYLNYYVHHLVDVRILGSVLLVVMMFWFILIAKIVILGAVINASMQ
                     SLKDPVFKKD"
     gene            complement(50798..52852)
                     /locus_tag="VU534_000368"
     CDS             complement(50798..52852)
                     /locus_tag="VU534_000368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000421632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HEU1513010.1"
                     /translation="MELLIYLILFLLVLIVSSTTNKLLPFLPLPLVQILLGIVIGLFL
                     PNTDFHLNTELFLALVIGPLLFREAEEADVTAILKHWRIIVYLIFPVIFISTLSLGGL
                     AHLLWFSLPLAACLAVGAALGPTDLVAFASLSERFSFPKRVSNILKGEGLLNDASGLV
                     AFQVALTAWTTGAFSLGQASSSLIFSILGGFLIGFLTAMTNRFLHTFLLSVRATDIAS
                     ELLLELSLPLVTFFLAEEVHVSGIIAVVVAGILKASRFKKITLLEAQVDTVTETVWHT
                     VTFMLNGSVFVILGMELEMIAEPILTNPIYNPLLLLLSLIALTFVLFVIRFIMIYGYY
                     AYRTRRLKKKLNKYMKDMFLLTFSGVKGTVSIATILLIPSNLEQEYPLLLFLVAGVTL
                     VSFLTGLLVLPHLSDEEEESKDYLMHIAILNEVTLELEKELEDTRNKLPLYAAIDNYH
                     GRIENLILSQENQDDQEDWAALKLLILSIESDGLEQAYEEGNISNRAYRVYQRYLKNI
                     EQGINRKLASRLTYYFLVSLRILRFLLHEVFTLGKTFRSWKNKEQSRLRALDYDQIAE
                     LYLANTEMIIESLENLKGVYRRSLISFMQESRLRETAIISSGAFVERVINRVKPNNID
                     EMLRGYYLERKLIFEYEEKRLITTKYAKKLRQNVNNLENYSLKEAANTLPYDMVELVR
                     RN"
     gene            complement(52864..53118)
                     /locus_tag="VU534_000369"
     CDS             complement(52864..53118)
                     /locus_tag="VU534_000369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000361102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1513011.1"
                     /translation="MDKQYLHEKLDAMRQNFVESTHHERAMGVLDQAHMSKKMLKIKK
                     KLVALEMERCQRKIEHKDCSKIDQKIKEQKEIFESCCKKD"
     gene            complement(53111..53668)
                     /locus_tag="VU534_000370"
     CDS             complement(53111..53668)
                     /locus_tag="VU534_000370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEU1513012.1"
                     /translation="MKRPLEMAHDFLAEVVTKEDVVVDATMGNGHDTLFLAKLAKQVY
                     AFDIQKQALEKTQERLHQADLTNAQLILQGHETLDQFVIKAKAGIFNLGYLPAADKSV
                     ITRPQTTIEALEKLCGLLVKGGRIAIMIYYGHEGGDLERDAVLDFVIQLNQQEYTAAI
                     YRTLNQVNNPPFLVMIEKLERYRHG"
     gene            complement(53652..54608)
                     /locus_tag="VU534_000371"
                     /pseudo
     CDS             complement(53652..54608)
                     /locus_tag="VU534_000371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002881980.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein.; internal stop;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
     gene            54700..55059
                     /locus_tag="VU534_000372"
     CDS             54700..55059
                     /locus_tag="VU534_000372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004249826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3397 domain-containing protein"
                     /protein_id="HEU1513013.1"
                     /translation="MGMILMKLASILLLILTLVVCIILTKLFRLKKLGRNFADLAFPV
                     LVFEYYLITAKTFTHNFLPRLGLALSILAIILVFFFLLKKRSFYYPKFIKFFWRAGFL
                     LTLIMYIEMIVELFLMK"
     gene            55269..56125
                     /locus_tag="VU534_000373"
                     /pseudo
     CDS             55269..56125
                     /locus_tag="VU534_000373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270419.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(56373..63074)
                     /locus_tag="VU534_000374"
     CDS             complement(56373..63074)
                     /locus_tag="VU534_000374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ig-like domain-containing protein"
                     /protein_id="HEU1513014.1"
                     /translation="MGKGHWNRKRVYSIRKFAVGACSVMIGTCAVLLGGNIAGESVVY
                     ADETLITHTAEKPKEEKMIVEEKADKALETKNIVERTEQSEPSSTEAIASEKKEDEAV
                     TPKEEKVSAKPEEKAPRIESQASNQEKPLKEDAKAVTNEEVNQMIEDRKVDFNQNWYF
                     KLNANSKEAIKPDADVSTWKKLDLPYDWSIFNDFDHESPAQNEGGQLNGGEAWYRKTF
                     KLDEKDLKKNVRLTFDGVYMDSQVYVNGQLVGHYPNGYNQFSYDITKYLQKDGRENVI
                     AVHAVNKQPSSRWYSGSGIYRDVTLQVTDKVHVEKNGTTILTPKLEEQQHGKVETHVT
                     SKIVNTDDKDHELVAEYQIVERGGHAVTGLVRTASRTLKAHESTSLDAILEVERPKLW
                     TVLNDKPALYELITRVYRDGQLVDAKKDLFGYRYYHWTPNEGFSLNGERIKFHGVSLH
                     HDHGALGAEENYKAEYRRLKQMKEMGVNSIRTTHNPASEQTLQIAAELGLLVQEEAFD
                     TWYGGKKPYDYGRFFEKDATHPEARKGEKWSDFDLRTMVERGKNNPAIFMWSIGNEIG
                     EANGDAHSLATVKRLVKVIKDVDKTRYVTMGADKFRFGNGSGGHEKIADELDAVGFNY
                     SEDNYKALRAKHPKWLIYGSETSSATRTRGSYYRPERELKHSNGPERNYEQSDYGNDR
                     VGWGKTATASWTFDRDNAGYAGQFIWTGTDYIGEPTPWHNQNQTPVKSSYFGIVDTAG
                     IPKHDFYLYQSQWVSVKKKPMVHLLPHWNWENKELASKVADSEGKIPVRAYSNASSVE
                     LFLNGKSLGLKTFNKKQTSDGRTYQEGANANELYLEWKVAYQPGTLEAIARDESGKEI
                     ARDKITTAGKPAAVRLIKEDHAIAADGKDLTYIYYEIVDSQGNVVPTANNLVRFQLHG
                     QGQLVGVDNGEQASRERYKAQADGSWIRKAFNGKGVAIVKSTEQAGKFTLTAHSDLLK
                     SNQVTVFTGKKEGQEKTVLGTEVPKVQTIIGEAPEMPTTVPFVYSDGSRAERPVTWSS
                     VDVSKPGIVTVKGMADGREVEARVEVIALKSELPVVKRIAPNTDLNSVDKSVSYVLID
                     GSVEEYEVDKWEIAEEDKAKLAIPGSRIQATGYLEGQPIHATLVVEEGNPAAPAVPTV
                     TVGGEAVTGLTSQKPMQYRTLAYGAKLPEVTASAKNAAVTVLQASAANGMRASIFIQP
                     KDGGPLQTYAIQFLEEAPKIAHLSLQVEKADSLKEDQTVKLSVRAHYQDGTQAVLPAD
                     KVTFSTSGEGEVAIRKGMLELHKPGAVTLNAEYEGAKDQVELTIQANTEKKIAQSIRP
                     VNVVTDLHQEPSLPATVTVEYDKGFPKTHKVTWQAIPKEKLDSYQTFEVLGKVEGIDL
                     EARAKVSVEGIVSVEEVSVTTPIAEAPQLPESVRTYDSNGHVSSAKVAWDAIRPEQYA
                     KEGVFTVNGRLEGTQLTTKLHVRVSAQTEQGANISDQWTGSELPLAFASDSNPSDPVS
                     NVNDKLISYNNQPANRWTNWNRTNPEASVGVLFGDSGILSKRSVDNLSVGFHEDHGVG
                     VPKSYVIEYYVGKTVPTAPKNPSFVGNEDHVFNDSANWKPVTNLKAPAQLKAGEMNHF
                     SFDKVETYAVRIRMVKADNKRGTSITEVQIFAKQVAAAKQGQTRIQVDGKDLANFNPD
                     LTDYYLESVDGKVPAVTASVSNNGLATVVPSVREGEPVRVIAKAENGDILGEYRLHFT
                     KDKSLLSHKPVAAVKQARLLQVGQALELPTKVPVYFTGKDGYETKDLTVEWEEVPAEN
                     LTKAGQFTVRGRVLGSNLVAEITVRVTDKLGETLSDNPNYDENSNQAFASATNDIDKN
                     SHDRVDYLNDGDHSENRRWTNWSPTPSSNPEVSAGVIFRENGKIVERTVTQGKVQFFA
                     DSGTDAPSKLVLERYVGPEFEVPTYYSNYQAYDADHPFNNPENWEAVPYRADKDIAAG
                     DEINVTFKAIKAKAMRWRMERKADKSGVAMIEMTFLAPSELPQESTQSKILVDGKELA
                     DFAENRQDYQITYKGQRPKVSVEENNQVASTVVDSGEDSFPVLVRLVSESGKQVKEYR
                     IHLTKEKPVSEKTVAAVQEDLPKIEFVEKDLAYKTVEKKDSTLYLGETRVEQEGKVGK
                     ERIFTAINPDGSKEEKLREVVEVPTDRIVLVGTKPVAQEAKKPQVSEKADTKPIDSSE
                     ASQTNKAQLPSTGSAASQAAVAAGLTLLGLSAGLVVTKGKKED"
BASE COUNT        18809 a        13594 c        11239 g        19576 t
ORIGIN      
        1 tatttgctga ttctatctac taatactata aaaaacaagt gaataagaca ccagaacatc
       61 ctctaatagg acctatggac ttatatcaat cccatatata ctgtttaagc aagatactat
      121 cctagttgac gctaacttcc tatcccactt attaattttt tatttatagt gaatctgaac
      181 aaatcaattg gggaatccaa gtcaatttct agtacttttt gaaaagtttc agcgtactat
      241 cgtaaaatga aataaaacat gcacaaattg cttagggaat ttaaaccaat ttctaacaat
      301 gtcttagaaa tcaaagtgta ctatttcaat ttcaatatac tacacttcat tttctcctta
      361 aattcagtct ctttttgaat caaaaaatcc tctgataaga cccagaggat aagaatttat
      421 ttcattgttg ggaagagcaa tacatcacgg atagttgttg tatcagtgag gagcatgcag
      481 agacggtcga taccgattcc caaaccacct gttggtggca taccgtattc aagagcttca
      541 atgtagtcat agtcgattcc tgtcgcttca tcatcaccaa gttctttggc tttagcttgg
      601 gcttcaaaac ggctaagttg gtcgattggg tcgttcaact cagtaaaggc attaccgtac
      661 tccttagtca tgataaagag ctcgaaacgg tcagtaaagc gttggtcttc aggatttttc
      721 ttagcgagtg gagatacagc tactggatgt ccatagacaa aggttggttg gattaaagtt
      781 tcttcaacaa actcttcaaa gaaggcattg atgatgtgac caacctcagt gtagtgtttc
      841 tcaactggaa ctttcttctc agcagcgata gctttagctt cttccaaagt catgtcttgc
      901 cagaaatcga caccagtaat ttctctgata gcatccacca tatgaacacg cttaaatggt
      961 tcgttaatct tgatttcagt accttggtag ttgactgggc catcaccttt gactgattta
     1021 gcagcgtgtt ggataatgcc ttcagtcaag tccatgatgt cttggaagtc tgcataagct
     1081 tggtaaactt cgatagaagt gaactcaggg ttatgagtag cgtccattcc ttcgttacgg
     1141 aagatacggc caatttcata gacacgttcc ataccaccca cgataaggcg ttttaagtga
     1201 agctcagtcg cgatacgaag caccatgtca atgttttggg cattgtggtg ggtgataaat
     1261 ggacgggcag cagcaccacc ggcttcatta tgaagaacag gtgtttccac ttcaaggaat
     1321 cctttttggt caaggtaacg acggatttca gagatgattt ttgaacgagt gacaaagcgt
     1381 tcaaagcttt cacgattaga aatcaagtca aggtaacgtt tacggtaaat tgtttcaacg
     1441 tctgtcaaac catggaattt ctcaggaaga ggacgaagag ccttagacaa gtgtgtgatg
     1501 tgggttgcct tgatagagag ttctcccata tccgtacgca tcacttcacc ttcgacacca
     1561 aggaagtcac caaggtctgc ttttttgaag atttcgtagt tttcttcacc gacagcatcc
     1621 ttacgaacgt agatctgaat ctggccttcg cggtcttgaa ggtgggcaaa accaactttt
     1681 cctttaccac gtttggttat caagcgtcct gcgatagtag ctgtttcgtt tttatcgtgt
     1741 aattgttctt tatcgaggtt ggcatattta tcttttaatt cttgtgaatt tgcagtacgt
     1801 tcaaaacgtt ttccgaaagg atcgattcct tgttcgcgga gcgcagccat tttttcacgg
     1861 cgaacgatct gctggtcatt tagttcttcc atatgttctg tagacatggg atcctcctag
     1921 ttttactcaa aattgaatac gatgagtcat tttttgcgac actcccattt tatcataaat
     1981 aagcaagaaa ttcacggata atctttaaaa actaaaaaga acctgacgct aaaatcactg
     2041 gaaagaagtg aaagtatctc ccgccccact agcgatatag ccaaatgctg ctttaggaat
     2101 aacttgttgc gccattggct ccaaatcata ggtattgatg aaatctacat gaccttctgc
     2161 attgcttgtt ttgtatgaca taaaatgtcc tccttaataa gtaagcgttt actttgtgta
     2221 ttacaaaaat atcttaactc tttttcaaaa cttttaaaat attttgtttg gaaatttcag
     2281 aaattttatg tctataataa aaatccttat aacggcaata aaaaatagat attatccaaa
     2341 gaagatttta agtgctacaa taactgtatt atttctagat gggaggttct atttttggat
     2401 tgatccattg ttgaacaata tctaccacta tatcaaaagg cattctttct gaccttgcat
     2461 attgcagttt ggggaatttt gggatccttt ctgctcggtt taatcgttag tatcatccga
     2521 cattatcgaa tccttgtttt ggcgcaagta gcgacagcct acattgaatt gtcacgtaat
     2581 acgccccttt tgattcaact cttctttctc tacttcggtc ttccccgaat cgggattgtc
     2641 ctatcttcag aagtctgtgc aacgcttggg cttgtctttt taggaggctc ctatatggca
     2701 gaatctttcc gaagtgggct ggaagccatc agtcaaaccc agcaggagat tggcctcgct
     2761 attggtctga cacctctaca ggtcttttac tatgtggttc ttccgcaagc aacagcggtg
     2821 gcactcccct cctttagtgc caatgtcatt ttccttatca aggaaacctc tgttttctca
     2881 gcagtggctt tggccgacct catgtacgtc gccaaggatt tgattggtct ctactatgag
     2941 acagacattg cgctagctat gttggtagtt gcttatctaa tcatgctgct acccatctca
     3001 ctggtcttta gctggataga aaggaggctc cgccatgcag gattcgggaa tccaagtact
     3061 ctttcaagga aataatctcc tgagaatctt acagggattg ggcgttacga ttgggatatc
     3121 catcctgtct gtcctcttat ccatgatgtt cagaacagtc atgggaatca tcatgacctc
     3181 ccattctaga atcatacgat ttttaacacg attgtatctg gaatttatcc gtatcatgcc
     3241 ccagctggtg ctactcttca tcgtttactt tggcttggct cgaaacttta atatcaatat
     3301 ctcaggtgag acttcagcta ttatcgtttt taccctctgg ggaacagctg aaatgggaga
     3361 cttggtacgt ggagctatca cttctctccc taaacatcag tttgaaagtg gacaggcact
     3421 cggcttgact aatgttcaac tttactacca catcatcatc ccacaagtct taagaagact
     3481 gctaccgcag gctatcaatc ttgtcactcg gatgattaaa accacttcat tagttgtttt
     3541 gattggggtt gtggaagtga ccaaagttgg acaacaaatc atcgatagca atcgcctgac
     3601 catcccaact gcttcatttt ggatttatgg aaccattcta atcttatatt tcgcagtttg
     3661 ctaccctatt tccaaactat ccactcactt agaaaaacat tggagaaact aaatgtctga
     3721 aactatctta gaaatcaagg aactaaaaaa atccttcgga gacaatccca tcctccaagg
     3781 actttctcta gaaatcaaaa aaggggaagt tgttgtcatc ctagggccat ctggttgtgg
     3841 gaaaagtacc ctccttcgtt gcctcaacgg cttagaaagt attcaaggtg gagatattct
     3901 tctggatggt cagtctatcg ttgaaaataa aaaagatttt cacctagttc gccaaaagat
     3961 tggcatggtc tttcaaagtt atgaactctt tccccatctg gatgtcttac aaaacctcat
     4021 cctaggccct atcaaagctc aaggaaggga caagaaagaa gtaacggaag aagctttgca
     4081 attactagag cgtgtcggtt tgctggataa acaacatagc tttgcccgtc aattatctgg
     4141 tggacagaag caacgtgttg caattgtccg tgccctccta atgcatccag aaatcatcct
     4201 ttttgacgag gtgactgctt cgctggatcc agaaatggtg cgtgaggtgc tggaacttat
     4261 caatgatttg gcccaagaag gccgtaccat gattttagta acccacgaaa tgcagtttgc
     4321 ccaagccatt actgaccgga ttatcttcct cgaccaaggg aaaatcgctg aagaaggaac
     4381 agctcaagcc ttctttacca atccgcaaac caaacgagcc caggaatttt taaacgtctt
     4441 tgactttagc caattcggct catatctata aaggagattc ttatgaaact attcaaacca
     4501 ctcttaactg ttttagcact tgcctttgcc cttatcttta tcactgcttg tagctcaggt
     4561 ggaaacgctg gttcatcctc tggaaaaaca actgccaaag ctcgcactat cgatgaaatc
     4621 aaaaaaagcg gtgaactgcg aatcgccgtg tttggagata aaaaaccgtt tggctacgtt
     4681 gacaatgatg gttcttacca aggctacgct acgatattga actagggaac caactagctc
     4741 aagaccttgg tgtcaaggtt aaatacattt cagtcgatgc tgccaaccgt gcggaatact
     4801 tgatttcaaa caaggtagat attactcttg ctaactttac agtaactgac gaacgtaaga
     4861 aacaagttga ttttgccctt ccatatatga aagtttctct gggtgtcgta tcacctaaga
     4921 ctggtctcat tacagacgtc aaacaacttg aaggtaaaac cttaattgtc acaaaaggaa
     4981 cgactgctga gacttatttt gaaaagaatc atccagaaat caaactccaa aaatacgacc
     5041 aatacagtga ctcttaccaa gctcttcttg acggacgtgg agatgccttt tcaactgaca
     5101 atacggaagt tctagcttgg gcgcttgaaa ataaaggatt tgaagtagga attacttccc
     5161 tcggtgatcc cgataccatt gcggcagcag ttcaaaaagg caaccaagaa ttgctagact
     5221 tcatcaataa agatattgaa aaattaggca aggaaaactt cttccacaag gcctatgaaa
     5281 agacacttca cccaacctac ggtgacgctg ctaaagcaga tgacctggtt gttgaaggtg
     5341 gaaaagttga ttagtcatta actcttaaaa ggaactggat tttaagctcc aatccctttt
     5401 taagatttta cctataacat cctgagtcta tctaagatgt tcaatctgaa cacagtgtac
     5461 atactttatc ttctattgca tatactttat cacataagat acgaatatcc tcttcactat
     5521 gactagcaat caaaattgtt gtcccttttt cactagagag ctttctaaac aatgttctca
     5581 tattttctac acttgattta tccaaggcat tcataggttc atctagtaaa agaatagagg
     5641 gattctccat aattgcttga gcaatcccta gctttttcct catacctagc gaataagttt
     5701 taactttctg gtctttttgc tcatatagac caactatttt cagtgtatca ttgatttcct
     5761 gattaccaac tactcctcgt atgcttgcca aatattgtaa attcttaaag ccactataat
     5821 aatttataaa accaggttct tcaatcaaag ctcccaaatt agctggaatt tttctctcag
     5881 gaacaatatt ttccccattg attaacactt ctccataaga cggactatat aaaccagcta
     5941 ttaatttaaa caatacactt ttccctgagc cattcgcacc agtaattcct ataatttccc
     6001 cctgtttaca actaaagtta aggttttgaa aaacacatgt cttttttaat ttcaactcaa
     6061 tattttttaa tgtaattatt tcattcattc tataaacctc ctcttttgac gagtgaaata
     6121 gaaaatgctt tgaaaaagaa agactaaaaa tagcaactga agaaataaat ctcgtcctat
     6181 atctccattc cctcgattca aaatataaaa tagataatta gttcgatttc ctacaaatag
     6241 accaccaaac acaatcatga gtaaaaagaa actaacgcaa gcaaagttca tttgtacatt
     6301 cgctcctagt gcgtataaca taaagcaaaa caagactaac acacaagcat tcaaagaatc
     6361 aactataaac aaaactccta tatcccagtt tggtaactgt aacataaatt gaatcactag
     6421 aacttttacc atgattaaaa tgagtccata aagaaaacag gtccaaatct gatacctaat
     6481 ccagagctta atagaagaaa atcgaatcac ttccataaag aaatcggatg ctcttctacg
     6541 atatacaact gctagaaaaa atgtatgaat aataaaccaa tgaagcaacc atatagataa
     6601 gactaaaaaa gagttttgac tcagattagg cccttttaaa atttctataa caagtctatc
     6661 atttccttct aaccaatacc ataatcctaa acaaatcaat atccaaaaaa gaacataacc
     6721 ccaaaagtac ttggtataga ttatctgatt caacctccac atgtgactac ttaactttcc
     6781 catttccaac ttttacactc tcctccagtt tctatgaaca gaaaatacag tcaatggaat
     6841 tatgatagat agtaatgtaa gccaataaat caatgcatac ggattggaat ttaccatata
     6901 ctgaaaaatt ggcaataatc caattatccc attgtccaac tgataaatcc agaataagga
     6961 ttctacaaat aaaaaagtaa acagaaatac taagctcatg tttgattttt taaaccaaga
     7021 aaaactgcta atagtaagta aggataaaaa gaaatagtat gctatataag agaaaaaaaa
     7081 tcctataaag aaactagcat tgtttgcaat acttatacca taaaattctc ttaaaaaatc
     7141 aacctccttt atctccaaag agaagctaaa accattacta aatgcaatta gaaaaatcaa
     7201 taaaaataaa gtcgccgtcc aaatccccgt actaagagct gctaatttga aactaaaact
     7261 ggtaaagtgc ttaattgatt tcagacgaat gcgacactcc aacctattaa aatagttatt
     7321 catcaaataa aaaaagaaca atatatatgt gaacggaaag caatatactc cagtcgtcat
     7381 atcttgaagt aaaactaaga tccattctaa tacatttgga tggattgaat attggcgaca
     7441 gcgcaataaa tatactgtac tagataaaac acaggatagc agtaatataa aataaaccaa
     7501 tactgctaag aaatcttttt tataaaattg aacaaattgt ttcattatac atagtcctct
     7561 gaatgtagaa aaaatgtacc ataaacaacc aaacaactaa caaataaaat aaaagcaaga
     7621 tgagcactaa ctaaggaaag actgatatct ttctgatatc ccaaagctag cgttgtcaca
     7681 ggttctaagt aagatagccc taaaatagcc caaaaaatac caccaaccat catataggca
     7741 actgggatga aaatagctcc tatttttttc ttcactagca aagcactagc tagtccaaaa
     7801 atagagaaca cagcgcccca aactccatac cagagagtcg ttacaagact atagagaaac
     7861 tgattggaat caaataattc ttttaaggca ccactataat ctccaatata aatttcctga
     7921 taaggagtca ctaaaagatt aattcctaat aataataaat aggggagaaa aaagactaga
     7981 aaagaagaaa taattacagt actacccaca atagccagat acttcttttt agaaattcga
     8041 cacaattgtg ctgttagaaa atgactctca gcatcctcta ttatctgact agaatagggc
     8101 agtgtacaga taagtgcagc tactaggcta atcggtgaaa atcctcgaat agaagaagcg
     8161 gcaaaaaaaa tcgataaacc ttcaatttta taaataccat tgaaagcaag gaaatttcct
     8221 aaactcatgc aaagaagggt caaaaataaa gacatataaa atcgaggtga ttgaacgact
     8281 cgtacaagat tacaaatgaa aaattccatc cttactcctc cttataataa aaatagggtg
     8341 tagcattctt ttttcatgct acacccacaa tcaaccatct ttaaggctta ctctgacaag
     8401 taagttaata agaatctgga ttccaagaac ctgaagtatg aattcttaca tgatttccaa
     8461 attgtggcgc catagctaat ctagtaccag aaccaatata attgtcacca cctccattat
     8521 agtacatgac aatcctagag ccagacccca atgaatatac cggggtaata tctgacccac
     8581 tataggcgct acgaatagag gtatttaacc ttttaccgcc accagtgctg tcattattat
     8641 taattccagc agaggagttt tctttctcaa gctcactagt tgtatccgaa ccccaacgcg
     8701 gcgacgttaa atcataatct ccaatctgtc tagctaaaac tgtagggaga aacaaactag
     8761 atgcatttgt aactacgcaa aaaaggaata tatttttctt cttttcatga catcgtcctc
     8821 ttaagaagtg ataaacaaga tagttgattg atcaatttga tacatattac attttcatta
     8881 tatcaacaaa agaaagcgtt gtcaattatt ttatttaaaa tattgtcata ttttaaataa
     8941 aatggtaaaa gagactcggt agcctcgtct ctctttatct tactgaccta accttcttgc
     9001 caattttctt ggtcttcttt aaagcgtttt agaagatcaa ggccctctgg cgtgatgtaa
     9061 ccttcttctt gggctagatg gataagctcg ctatagtttg aaagcgtcac aagtttaaca
     9121 ccagcatctg caaagttctt atctgctttt ggcaattggt agctgaaaat cgctacaact
     9181 ccaagtacat ctgctccttc tcgcttggct gctgctacag cttcaagaac tgaaccaccc
     9241 gttgaaataa ggtcttcaac cactaccatt ttttgacctt gagctacgcg accttcgatt
     9301 tgattaccag ctccgtggtc ttttggttta ctacggatgt aggcaaaagg caagtccatc
     9361 ttatcagcaa taatggctcc gtgtggaatc cctgctgttg cagttcctgc aatcacttct
     9421 acttcaggaa aggcttcttt gatagcttcc acaaaaccat tttcaattag ggtacgagtt
     9481 tctggatagg ctagtgtcac acgattatca gtgtaaatcg gtgacttgat accagatgcc
     9541 caagtgaagg gttcctctgg tttgaggtaa acggcttgga ttttcaagag gtggctagcg
     9601 atatctttag caagtgtcat ggtattctcc ttttattttt ctaatctagt tctttaattc
     9661 cagtcctgtg tccattcatc cttgatggca tgataagctg caacaggatc ctcagcttgg
     9721 gtaatgggac gtcccactac gatatagtca ctgccgattt gataggcatc agcaggtgtc
     9781 atgactcgtt tttgatctcc aactgcaaca ccagctggac gaatccctgg tgtcagacag
     9841 ataaaatctg gattggtagc ctgcttgatg acttgtactt cctgagccga gcaaacaaca
     9901 ccatccaagc cagcttcagc tgtcttcttg gcatagtgaa tcacagactc ttgcagactg
     9961 gtttggatat tttgaaactc ctgcatctga gcttctgacg ttgatgtgag ctgagttaca
    10021 gcgatcaatt tggcttgact cccaagacct tcacgcgccg ccttcatcat ctctacacca
    10081 ccagccgcat ggacattagt catatcgaca ccaagctgag acaagatctt catggctgac
    10141 ttgactgtat taggaatgtc atgaagtttg agatccaaaa agacactatg acccaaacct
    10201 tttaagtagg acacaatctc aggccccgct gcgtaataaa gctccatccc taccttgaga
    10261 taaaggcttt cttctgctgg gaaaagagct aaaaattcct tgaccgcctc aaaactagga
    10321 aaatcaagag caatgattgg acgatgttct cgcataggtt tctcctttta cctttactag
    10381 tgagagagtc tggccaacag aagccacgaa aaaaggaacc tgccaacagc aaggttccac
    10441 gaaaaatggg tagtctccac cctttcaccg tctaacctta gctgcctctc tggactgctt
    10501 taaaggtttt ttactattct attatttcta ctagcacttg tcaagtaaaa acagctaaat
    10561 ccatgttgac tgctattgaa cacctcacaa gactctttcc aaaagaatag ttaaagactt
    10621 tcacttcgga cagagaaaaa gagtttgctt gttacccttt aattgaacaa atgggaattc
    10681 tgttttattt tgcggatgcc tattcatctt ggcaaagggg aagtaatgag aatgcgaatg
    10741 gacttcttcg tgagtatttt cttaaaccga tttggcaaca attaccgaaa aaatccttaa
    10801 tgatgctttg ctagcttatt aatcaccgtc cccaaaaata cttggattac aagacaggtt
    10861 ttgaagcact ttttgaagca cttatagagg agatttaaaa atgttgcatt ttttattgca
    10921 atttatcagt tatcttatca cccaaaactt ctgcaattag tatgagcact attgttattt
    10981 ttcttttttc gtacactcaa atcaaaatat agcaataaga ctattctgta gaattgctgt
    11041 caaaaagatc agttcatttt ttccttccca cttgtgttta taatcattaa aataactcaa
    11101 ttaagaaatt ttctttttcc taatagttat cgtaattaaa gttaatagaa gaacaatcca
    11161 aataagtagt gttagattag gaattagagt tttattccat gaaaattcct cccattttgt
    11221 gaaaaactta gtaaatagtc ccataaaact ataatctgtt atcttcgcaa ctgtcttatc
    11281 caaaccagat agcatcggta agaaagcaac taaaatcata gcaggaagac tgataacctg
    11341 agctactact tggctcttcg cggttaaacc tatcaataaa tagaataaaa tgatggataa
    11401 agaggttaga agaacgattg taatataatt aaaagtatgt acaattgtaa ctcctaaaat
    11461 aagaggagta gttcccataa tcacaaaagt tagcaaaaaa ggaagaaaca tagttgataa
    11521 aatgtattcg gagcctttaa caccactcaa cagaagagtt tgtaaattgt acttttcttt
    11581 ttcttcagac aagataatag ttataggact tccaacagcc aaagaaaaag aaaaaggtaa
    11641 acacatcatc aaaagaacta atgcctgttg atcgttgacc ttcccctgtg tttccataag
    11701 atatttataa aaatatgtga aagcaaaagg cactaaaact tgcaataaaa tactcttatt
    11761 ggaaaggatg atttgacaac gcaaccatac caaagccaga aaccgtttaa gcatttagct
    11821 ttcctcctgt taatgtgata aaaatatctt ctaaagtagg ctcacatgaa tgaattgaaa
    11881 aaatattttc cagatcagtc tgagatacct gttctagtga tgtaaaatca aaagttatct
    11941 gattcccatt ataatctgta accttaatct ttttatcttt attatatctt tgaatgagtt
    12001 cagaaggagc tccttgctca actaatttcc ctttatttaa taaggcaaca taatcacata
    12061 aaagagttgc ttcattcata tcatgagtcg ttagaaaaat cgttgtccct gctgttttca
    12121 attctaaaat taactcatga attgttcgag aagttgtggg atctagacct gaggtcggtt
    12181 catccagaaa gagtacagcg gggttgttga taagagctcg tgctaaaagc attcgttgcc
    12241 tcattccagt ggataatttt cctgctacca tcttgcgact atcatataat cctactcgct
    12301 ttaacaaatt atcaacacgt gatttactaa tattataaaa tttactataa aaaagaagat
    12361 tgttatacag agacattttc tcataaaatc cacttgtatc gctaaccaat ccaattctct
    12421 ttaattcacc gcttgttaaa ttttgagatt tttgtcccaa aataatagat tgtcctttat
    12481 cggcaaggaa ctgcccagtc agaatattaa tcgttgtggt ctttccagaa ccagatggtt
    12541 ctaaaaatcc aaaaatctaa ccttctttaa cagtgaagct tatattattt aaagctattt
    12601 tatcaccaaa actttttgat aaatggctaa cttcaatcat actcattgca cctcctttat
    12661 attctacatt tttacttaac atctatttac ttatctttat caaataaacg tcttaaaaaa
    12721 aacaataaca ttaagcatat aaccgttagc aagattgttt caatattatt gataatacga
    12781 tacattctca agcagtataa aataattata tatatgcaaa tgctcattat acctattttt
    12841 ttaaacatac taagcctcct tgctaaataa taaagttata taataactaa gacacactat
    12901 acctaacata ataaatatcc acagcattaa aaatattatc ataccaataa aaatatccac
    12961 tggtaactga ataaatgttc taaaattaac aagcaaaaat aaaatctcaa acgatgaaaa
    13021 aagccatact atattttcca atgatgtttg aatattttta ttgtagtaag cataatatat
    13081 agcaaaaata atacccaaga acaatactat taattgtgtt tctataacag tgaactgccc
    13141 aatagcagat aaaaaagcta ctcctcctga taataagcaa aaacaaactg aacgaataaa
    13201 tgttttcgct ctaatattgt tatctttcac tttattattt ttttacaaat tggacattct
    13261 ccgttttcca gaacatattt ttcttgactt agagcatgat ttctcatatt ataaacgtaa
    13321 gcgttatcta ttaggatttc attataacat cccagaaata ttttaattat taaattagtc
    13381 attatccctc ccaaaatagc aggcatctct ggtgtagtcg gccactttgt cttatcagat
    13441 aaagtgtact tatttatatc tttgtttata ttccgacaac caaagcaaga accgatggta
    13501 gggatatata tattatcaat aataagatag catccattaa accctcctga tatgtaggat
    13561 atcttatgcg atacagcaaa ttgattgaca atttttataa tatcaatggg cgtatcaatt
    13621 gctttaacga taaaatctat actcccatat tccgcaacaa tttttctaat tcttctactg
    13681 aagaaacttt aatagaaata ggtactacct gaacatctga attatacttg tgtatttttt
    13741 cagaaagaac attaatcttc tccttaccaa catccgactc tgtataaaga atttgcctat
    13801 ttaaatttga tggttctatt atatcgtaat cagcgacaat aagtttcctc actccataca
    13861 tacttagact tagagatata taacatccta agactcctgc tcctaatact aatactgttt
    13921 tattctgtat tttattatac tcttcattat aaaataacga atagtaacct ttagttctag
    13981 aatatctact atcaatatct atctcatccg aaattaaaat ttgttcattt atagttcaaa
    14041 tgttagttta ctgcctaata cttcttctat ctctaatagt tccttacaac tattaaatag
    14101 atcgttgata aattcttgcg aaatttgagg ttctatagct atttcccgca tactccgacc
    14161 acgtaaatac attatacctt cttttttata agcaaaaaca taactattta cgtagaacat
    14221 atttcgtcct tcctatcata tataatatag aaagcagtat agaaacaacc acccctccta
    14281 tactacgaac aataatattg ggtgtcaaaa actgtaatag ttgactcaaa ggaaaataaa
    14341 taataacaaa tgctattaaa agttgaacta tatattgaaa attcaagtta ttattgttag
    14401 aattcaagta tcttaaaata ataccactat catactgaaa aaaaggaatt gaattaataa
    14461 aaatcatacc taagttaatg ataaaaaata agagtccaag caatttatac gatgtgaaca
    14521 ataaaacaag taaacctgta agtgataaaa tcgaatttga agcaattcct gctaacataa
    14581 ttttcaaaaa ttgtttttta ttttttagga attgcacccc acttaaatct acaaaaaaag
    14641 ccaaattaaa caaaagtagc attattccac aatttgggat ctcaatttga taattattag
    14701 caattattgc atgactaatt tcatgtatcg ttgcaaatat aatgacaaca agataggatt
    14761 ttttcaaaat tcttattaaa tcttttatag tttaattttt cagataatgt tatattaaag
    14821 tcccaagata ttttaaaaat atttcttccc tactaacact aataagtccg atatggtaaa
    14881 ttcttgacct attagttgct ctaaccattt ttttcctgtt tcccaactaa tacatgtttc
    14941 ttactggatg gtatatataa atgatagtgt ccctcataag gagtaggtaa tatcttaatc
    15001 ttatcaacaa ttctcataac aaacctaacc tttaataaat aaaagagggg ttaagtaaaa
    15061 catactctag tccctcagtc cgcaatcaat aaaataatga ctaattctat taatctcttg
    15121 ctgcaagact aatacggaaa atttaaatga ctgtctaaaa tgaaattgaa aaagcttgat
    15181 gttagtaaat gaacaaactt caacaaccag caagagcaag gattgctaaa ccaaatccga
    15241 tacctgttgc aagtccagct gaaaaatcat taactggtac tgaaatttct tcaatttcct
    15301 caaataaaaa gttatcttgc atgattatca ctccctatct ttttaacaac aggctactcc
    15361 aattaagaga actaccccag ttccaagtaa aacttccccc aaaaattcac catctgtagg
    15421 ggctacgatt tcttcaattt cttcaaataa gaatacttca tctgacatat gtgttacctt
    15481 cttcatcaaa aattattttg taatcgatta cattgcagat gtaacataaa gaaaaacaga
    15541 tgtcaaatat taaacgtaaa aacatggtca ctaaagaact ataagagaaa aggtaaacct
    15601 agcgacgcga tgaacgctgg gtcgtttggt ttcgattgct ctcttcctct tgttttttct
    15661 gttcttcttc ttgttttttc tcagcttcct tggcctcttg tttggctttt tcctcagctt
    15721 ccataattaa tttatccgcc acagtgtagc tgtagattcc agcttccatg tcgaccacac
    15781 tcggttctga caattgaggc ttaatcttac tgtaatatgg cagtttctta ctcatttcag
    15841 atagaggaac caagacttcg tccgaatcat tcatggtcaa tcgaattaaa tcggatgtca
    15901 ccttgcttgg ggctaattcc accttttgga tagccgcctt gagttctggg ctaatttgag
    15961 caagttctga gacaaaaact ttgatttgtt cactatcatt aaagagaact gataaataag
    16021 tttctggtaa actgttcaga ctcacagaac tagtctcaag ctgaccactg gaaagaatag
    16081 gataatgatt ttcaccagaa atatagtagg ccacaatatc atattccttg accttaatag
    16141 tgaacttagt tggaaattga tagacaagtt gagctgattc aacccaatag ttagacttaa
    16201 tctgcttttc atattttgcc ttgtctagca gaaggttaat cgtataatcc gaatcctgaa
    16261 tgcctgaagc ctgtcgaata tcatcagctg tagtttgcac cgttccctca acacgaatat
    16321 ctttcatggt cgcataagga ctgagcaagt aggcagagac aaacaataga agcagacttg
    16381 gaaataaaat cgtgaaggct cgcaagatat ggataccagg aatctttgct ttggctggtt
    16441 tttcctttgt agccttttta gcaagctttt tatcctgttc ctccttctct ttagactctg
    16501 gttcttcttt ctcttctttc tctttgtcag cctctgagga tgctactttt tcttcagact
    16561 cttccttagc tgattctgaa tcttcctggt ctgtttcact ctcctggtcc tgtttatcct
    16621 ctgacttctc agattcttct cccattcgag cttgtctttc cttttccttc tcctcagcta
    16681 gagccgcctc ttcttcagcc ttctttttta gatattcttg gtttcgtttc tgccattctg
    16741 ataactcttt caattcttcg agggtttctt tgtcctcatt tttcttatct tttgacattt
    16801 actttcctta tgataaatct tttttcaaca attgataaaa atctgctaga gatttcaatt
    16861 ccttagaagc tttcatctta gcttggtaat cttccttgtg acttagtaag tgagaaagct
    16921 tctcttccaa actatccaag gtcaaatcgc tttcttgaag gtcttctgca tagcctttct
    16981 taacaaagta agctgcattt tcaatctggt caccacgact agcttcacga ccaagcggca
    17041 caatgacatg caattttgct atcgccaaga gctcaaaaat cgtattggca ccacctcgtg
    17101 tcacaacaat atcagccaat tccatcaagg gttgatagag atcggtcaca tagtcaacac
    17161 gaaaaagatt ttgcctcaac tcattcagac tagaatctcc agttagattg ataatattgt
    17221 agcgctctgt tagttctttc ttatggtctg tcaccaattg gttaaagaca cgagcgcctg
    17281 cagaaccgcc aacaaacaat acagttggca atttgggatt aaagtgggtt tgaatatcca
    17341 ccaattcatc tggttctgga gtgtttttgt ccgaaacctt ggtcaccgct cccacatgct
    17401 caaccttagc caaactcgaa gcttgttcaa aggttgaata catcttagtc gcaaatttat
    17461 aggcgatttt attggccaag cccatagaca ggtcagattc gtgaataaag acaggcactc
    17521 ctgacacacg cgcagcgata acaggcggta ctgagacaaa gccccccttt gaaaaaaggg
    17581 tctgtggacg cagtcgcaac atgataaaga gcgattggac aattccccaa ccaactttga
    17641 agacgtccag catattttgc caagagaaat agcgacgcaa ttttccagtc gcaatagaat
    17701 ggaaggtgac atccaaacct gacttaagga tttcttggtg ttcgatacca cacttgtccc
    17761 cgatatagtg gacttcccaa ccatcttcga tgaacttggg cattaacaaa agattgaggg
    17821 taacgtgtcc aaccgtcccc ccacctgtaa agacaatttt tttcatatta ttcttttaac
    17881 tccgctactg tgtcgataaa gaggtcgcca cgtacttcaa agttagcata catatcccag
    17941 ctagcattgg caggactaag aagaaccaca tctccttgag tcgcaagctc ataggccttg
    18001 cgggtcgcat ctgcaatatc tgtcgcctcc acataagcga caccagcctt gtctgctgcc
    18061 cgtttgacac gttctgcaga ttgacccagg atgaccatct tcttgagtcc agtaatgtct
    18121 ggcaccaatt cgtcaaactc attgccacgg tccaaaccac ctgcaatcaa gacgaccttg
    18181 ctgttgtcaa atcctgacaa ggctttttga gtagccaaga tattagttga tttactgtcg
    18241 ttatagaatt taacaccctt gatgtcatcc acaaactgga gacggtgttt gacaccaccg
    18301 aaggctgaaa gagtttcctt gatggtttga ttgtccacat cacgaagctt ggctacagca
    18361 atagtcgcaa gggcattttc cacattgtgg ctacctggaa caccgatttc attcgctgcc
    18421 atgactactt caccacggaa gtagagttga ccatcttcca gataagctcc atcaaccttt
    18481 tcaagtgttg aaaatggtac aacagtggct tctgtcttgg aagtcaagtc ttttgccaag
    18541 tcttgattaa agttcaagac aaggaaatca gctgctgtca tcttgttctg gatattccac
    18601 ttggctgcta catattccga aaatgaccca tggtagtcga tatgagttgg catgaggttg
    18661 gtaataaccg caatctctgg atggaattct tgaacaccca tgagttggaa agaagaaagt
    18721 tccataacaa gcgtgtcctt atctgatgct atttgagcaa cctgactagc tggatagccg
    18781 atattccctg ataaaagacc atgttggcca gcagcagtca aaacttcccc aatcatagtc
    18841 gttgtggttg tcttaccgtt cgatcctgtg ataccaataa tcggtgcttc tgaaatcaaa
    18901 taagccaatt ccacctcagt caagactgga attcccttgg ccaaagcctt ttcaatcatg
    18961 ggattgttgt aggggatacc tggatttttc accataaggg caaactcttc atccaagagt
    19021 tccaaaggat ggccacctgt aatgaccttg atcccttctt ccagcaaact ttgggcagct
    19081 ggattgtcct cgaaaggttt cccatcattt actgtcacaa tggcacctag cttgtccaac
    19141 aaacgagctg cagattcacc agacttggcc aaacctaaaa caaggacttt cttattttta
    19201 aattgatcta ttactttcat gtctcgaact ccatttctac tcctactatt ttaccatttt
    19261 tatggaaata aaaaagccac aaagtgtgtt tgtgactctt tcttctaact gaatcttacc
    19321 atatcatcta tgtgataaat cggtaactcg aatgacctga tccacttgct cccaaatcag
    19381 aggattatgg gtcgcaataa taatggtccg attcggattt tttaaagatt ctaggatgga
    19441 aagtaattcc tcagagtttt tggggtctaa ggaagcggtt ggttcatctg cgaggatcaa
    19501 aggtggatcc tttaaaatta tcttcgctag tgcaacacgt tgtgcttctc ctcctgataa
    19561 ctcaaatata ggttgcttca aatccaaata agagaggttt acacggttta gagcttgttt
    19621 catcaaagag attttctctt tttccttcaa ctttttacca actaaaccca gattgagatt
    19681 ctctttgacg gtttggcttt caattaagcc aaaatcttga aataagtatc ctaagtaatc
    19741 tctaaagaaa acagaaggct tgatgtcctt aagagaagtg ccatcataga tgatttgccc
    19801 tttgtcatat ggctccaatc gtccaatcat attcaagagt gttgtcttac cacagccact
    19861 tgtaccgatt aaggcataaa ttttcccacc ttcaaaatga agattcatat ctgaaaatag
    19921 ctgacggctt ccaaattttt tagatatatt ctttagttca atcatcctat tttcctttca
    19981 taattgtcat agaaacacga gattctttct gcgcttgacg gtaaagcgtc aaaactgcac
    20041 tagctagaaa gaccaataaa gtgagcaagc caatcaccaa gtctcgactg cttaaaataa
    20101 agagactagc accaaataca aaactagcaa attggctaac catatactga gcatgtgttt
    20161 caaaaaatcg taaacctgaa attcgtttaa tcaagatatc tcggcggaat tgctcgaaat
    20221 atagaagatt gacagaataa aagagtaaca aggaactggc tattccaaca atagctccta
    20281 agattaaagt tgctgtttca gtttgaactt cattataacg agttagataa acacttcttc
    20341 cttctttaag ataggatact tgctcataaa ttccagcttt cttcaagagt tctagcccac
    20401 tctcatatcc tttgataaag agttgttttc cagcattgat agaccaacta gataaggata
    20461 taaaactatc acctgtagaa gtcggcgtga ataccactaa aatcggatca gtcaaatact
    20521 gagtagatac gggattctca ccgttattat aaacaaaccg cttttctccc attgaaagat
    20581 aactaacgtg cgctttcatc tcataatcca aaggagcact tgcctcctca ccagattttc
    20641 cataataact caatctttct tcaaaaactt tcttaagttc tgcttctcga gagcgcaaat
    20701 gttctgggag caagaggata aactcacctt tttggagatg ggctaacttc tgtttggtct
    20761 cagcatctac cacgaccttt tccttgtcca aataactggg actaacatag agcgtattag
    20821 catctggact ataggtatcc agtgtctctc cctgttcatt ttttccttgt ggattggcaa
    20881 aatggagcag attatccttt acataaagag cttgttcttc ttcgattgct tccttggcaa
    20941 aggcatacca cttgctctga ttttctgtat cttttcctct atcacctaag ccaaaggaaa
    21001 tctggtaata gtctgctctg tcctgccatg cttgttttga aatttcaagt tctttcaatc
    21061 gttggtaaga cgtcaaacct gtcttaacag cgtagcctac tgtaaaaaca gctactaact
    21121 gacacaatag ggttaaagcc atcaagcgtt taaggggtaa tcttccctta ataacgggaa
    21181 ctaatgcttt gtaactcaaa ctcattaggt aaaggagcat tagtaaaatt gaaatcgcca
    21241 ataaaaacaa cagatagaaa ctaatcccaa aaccataggt ggctaacaag ataggataaa
    21301 acaaaccttg actaaaaaga acgactcccc cacctaggaa ggaaaggagg gctgatagaa
    21361 ggagccattt gatatcagta gataaagaat gccccatgat ggataagaga gtctgaccag
    21421 aaaagagttt tatacctgct gctctcattt ccttaatccg agtgataatc actaaagcaa
    21481 agaaagataa gccaaatatt gctaaactaa ttaaaataag gggatttagt aatattcgaa
    21541 aagcaagaaa atagggcggt atctttcggt cagcacttgc tttataaccc aaatctccta
    21601 atttatcggc aagcttttct ttcgtcaagg agcctgacaa aaggagataa ctatttagcg
    21661 gatcactacg ttcacgactt tcttggctag cttcttggaa ttcttttggt aaagttccct
    21721 gaccataagt tgcataagta aagtgagtcg tcccatcctt actcggctct acaattcttc
    21781 tagctattaa actctgttct gagtttgcaa aattctccaa ttcctgttca aatacctcac
    21841 gcgtcggttc ctgagtatct tttttgacac gaagtaaaga aacggaatca tagcttgcat
    21901 ataaatattg tggcgcacgt aagacaataa tccaagcaag gaagaagctg agaaaaaaag
    21961 ttgataataa tatgaatagt ttcttcatag tagactcctt gtaaacaaaa ttccccctgt
    22021 aatttcttac aaggggaacg atttaaatca atgaacgatt agtcataatc acagtaaaat
    22081 gctacttgtt ctccccattt agtccaaatc catgcatagg aggtttttcc agcaggagct
    22141 tctcctttat cagaatgacc atcccatctg ctcacgatag atgaataatg atatttttta
    22201 ccatgatagt aatttgaaaa agcctaacca cctcctgaac cttctccata tgtccatact
    22261 cctccatctg gatattatac agcagctgat gcagctccca ataatgtaaa acttgaaata
    22321 agagctagag caagtaatct atgttttttc gttttcattt tattttttct ttcaaaaaaa
    22381 gcacaccttg agcaacaatg caacaaaata aatcctcctc tctcttttat tgaaaccgct
    22441 ttcttatgtg ataagaataa cttttttatt atttgttgtc aaggaaaaaa tcgaattttt
    22501 tagatatttt actatattac ctctgtgaat aatattatat agtagtttta tttcaaaata
    22561 atatgcaacc agtactaacc aaatataaaa tagatgccat taacgaattt tattcaagtt
    22621 tttcccattc atactataca agtaaaagag atggtgttaa ctaaaaagca attcaaacta
    22681 ttgtaaaatt cctagcaaaa agagagccga aactctcttt tttatcttct tttacttttt
    22741 ttgactggca tgagtgtgat gtctctaaca ctaaagtaag ctaggatcaa catggctatt
    22801 gctaggaata tttctgttgg taattgaaaa attttcagaa aagatagaac caataaaatc
    22861 aagagtgcca ctaaaataca taccatagcg acgatattga cagtcccttt aatgctttct
    22921 ggtgtcgcaa atacatagag taggagcagt aaaattccta ggactaaata gaccatcttt
    22981 ctctctttct agctcttatt cagctgattt tttcttcttg ttagctttct cacgctctgc
    23041 tttgttaagg atttgtttac gcaaacggat agactcaggc gttacttcca tgtactcatc
    23101 gtcgttcaag aactcaagag actcttcaag tgtcaagata cgaggcgtct tgataacagc
    23161 tgtttggtcc ttagtagctg aacgaacgtt ggtcatttgt tttgccttcg tgatgttaac
    23221 tgtcaagtca ttttcacgag agttttcacc gatgatcatt ccttcataaa cctcagtacc
    23281 tgggttgaca aagatcgtac cacgttcttc gatagacatg attgagtaag ttgtagcctt
    23341 accagcatcg atagaaacaa gggcaccacg gtgacgtcca ccaatttccc ctggaatcaa
    23401 tggcaagtat tggtcgaagg tatggttcat gataccgtaa ccacgagtca ttgataagaa
    23461 ctcagttgag tatccaatca aaccacgcgc tggaacaagg aagaccaaac gagtttgacc
    23521 attaccagtt gaaatcatat ccaacatttc acctttacgt tcagaaaggc tttggataac
    23581 agacccttgg tattcttctg gagtgtcgat ttgtacacgt tcaaatggtt cacatttaat
    23641 accgtcgatt tcttttacga taacttctgg acgagatact tgaagttcat agccctcacg
    23701 acgcattgtt tcgataagga ttgacaagtg caattctcca cgtcctgaaa cagtccattt
    23761 atctggtgaa tcagttgggt caacacgaag ggaaacgtct gtttgcaatt ctgcctgcaa
    23821 gcgttcttcc accttacgag aagttaccca tttaccttct ttaccagcaa atggtgagtt
    23881 gttgaccaag aaagtcattt gaagagttgg ctcatcgatg tgtaggattg gaagagcttc
    23941 tactgcatct gtcggagtga tggtttcacc gacaaagatg tcttccatac ctgaaacggc
    24001 aatcaagtca cccgctttgg cttcttggat ttcacgacgt tccaaaccaa agaaaccgaa
    24061 gagttttgta acacggaagt ttttagttgt accgtcaagt ttagaaaggg taacttggtc
    24121 cccaacctta actgtaccac ggaagacacg accgataccg atacgtccaa cgaagtcatt
    24181 gtagtccaaa agtgacactt ggaactgcaa aggctcatct gagttatcta ctggagctgg
    24241 gatatggtcg ataatcgtgt caaagattgg tgccatagtc gcttcttggt cagctggatc
    24301 atctgacaat gaagaagttc cgttgatcgc tgaagcataa accactggga aatcaagctg
    24361 gtcgtcatct gcaccaagct cgatgaaaag ttccaagact tcatccacta cttctgctgg
    24421 acgagctgat ggcttatcga ttttgttaac aaccacgatt gggacaaggt cttgttccaa
    24481 ggcttttttc aatacgaaac gagtttgtgg catggttcct tcataggcat ctacgaccaa
    24541 gacaacaccg tcaaccattt tcatgatacg ctcaacttct ccaccaaagt ccgcgtgtcc
    24601 tggtgtgtcc ataatgttga tacgagttcc gttgtaagca acggcagtat ttttagcaag
    24661 gatggtaatt ccacgctctt tttcgatatc gtttgagtcc atagcacgct ctgccaattc
    24721 agtccgtgca tcaagcgttt ctgattgttt caataattcg tcaaccaggg ttgttttacc
    24781 gtggtcaacg tgggcgataa tcgcaatgtt acggatatct tctcttaatt ttgtcatgat
    24841 ttcctctata atattcaaaa tttattttct aactgaacga ttataccata atttcaaata
    24901 aataacataa ctcaagcaag tgtaaatgtt ttcactctgc ttttcttttc acgtcaagcc
    24961 ttttcaaagc gagcgactta tgataagata ggcacagtat gcgtttagat aatttattag
    25021 ctcaagaaaa aatcagccga aaggccatga agcaagcact cctcagaggg gaaattctag
    25081 tcgatggttg cccagcccgc tccctagctc aaaatatcga tacaggacta caagaactcc
    25141 tttttcagga tcgaatcatt caaggctatg aacacaccta tcttatgctt cataaacctg
    25201 ctggtgccgt tacagccaac aaagacaagg aacttccgac cgtcatggac ctgcttccat
    25261 ctaacatcca gtctgacaag ctctatgccg ttggccgact ggaccgagat acaacgggac
    25321 tcctcctctt gaccgataac ggtcccttgg gctttcagct cctccatccc caatatcatg
    25381 tcgataagac ttaccaagtt gaggttaatg gacttctaac acctgaccat atccaaacct
    25441 ttcaaaaagg aattgtcttt ttagatgaca ctgtctgtaa acccgcaaaa ctagagattc
    25501 tatctgcaag tccctccctc agtcaagcct ctatcaccat ttcagaagga aaatttcatc
    25561 aaatcaagaa aatgttcctc tcggttggtg ttaaggtgac tagcctcaaa agaatccaat
    25621 ttggggactt cacattgaac ccagatttag cagaaggtaa ctaccgccct ttgaaccaaa
    25681 aagagttaca aatcattaaa aactatttag agatgagtcg ataaaacaaa aaaagcttta
    25741 aaactaaagc ttttttcttt tatttaccga aaaattaagg cgattgctac aatccagtta
    25801 actacagaaa tcacaattcc taagatatta agaatctttt ctattttata gtctaattgt
    25861 gactcttttt ggtatgaaat agccaagacc aatcctatga tacccaaaat caggcctaca
    25921 attggaaata acaaaccaag aataatcgac aagataccca caaaaagtgg atttttcttc
    25981 ttttctttta tgttctaaga actccttaaa ttttatacaa attaattata ctataaaaca
    26041 atagcttcat cctatcattc gactaatttg gaaataaggt tagctagtct tcactttccc
    26101 tttccaagaa tccaagccat aagaaaggat ataaatctca gaaaaacctt gttttttcaa
    26161 gtaaagagct gcatttgtaa ctcgttgcgc acgttggttt tcgtagagaa ggacaggttt
    26221 atctttacga agggctgcaa gactagtttt caactgactt gaaggaatat tgcgtgcacc
    26281 aaggatatgt tttctgtgga attctgctgg gtcgcgcaaa tcaatcaatt gacccgtacg
    26341 aatcaaggct tcaaactcct cattgtccac aattttagcc gcacggcgaa tacgaagata
    26401 gttaaagccc atccacgcca acattgctag tataagtgcc cacaaaatcc aagtaaccat
    26461 tagttctttt ctccattttt ctcaatataa tccaattcta ccttgtgctc tctgcgaaga
    26521 actgcttctg cctctagata gtctaattta tccatcaacc ctgcatcgta aatccgagat
    26581 agttccaact tcatcagttc aatatcatat aagcgttttc ccatgtaaac aataatacca
    26641 aatcgtttga ggaattgctg cacatcatag aatgttttca taagactcat tctagcaaaa
    26701 ttttgtgttt ttttcaagaa gagactcaca caatgctcct tattttccta tcttctttag
    26761 cgattctaag gcaagtatgg tacaataaaa acatgagaat tcaacaatta cattatatta
    26821 tcaaaatcgt cgaaactggc tccatgaatg aggcagccaa gcaactcttt atcactcagc
    26881 caagtctctc caatgcagtg cgagatttgg aaaatgaaat gggcattgag atctttatcc
    26941 gcaatcccaa gggaatcacc ttgacccgtg atggcatgga gtttctctct tatgcccgtc
    27001 aggttgtcga gcagacccag cttctggagg aacgctataa aaatcctgtc gcccaccgcg
    27061 aactctttag cgtttcgtct caacactatg cctttgtggt caatgccttt gtctctttgc
    27121 tcaagaaaag cgatatggag aaatacgaac tcttccttcg tgaaactcgg acttgggaga
    27181 ttatcgacga cgtcaagaac ttccgcagtg aggtcggggt cctcttctta aacagttaca
    27241 accgtgatgt tttaaccaag atgctggatg acaatcacct gctagcccac catctcttca
    27301 cagcgcaacc gcatatcttt gtcagcaaga ccaaccctct ggcaaagaaa gacaaggtga
    27361 aactgtctga tttggagaat ttcccttacc tcagctatga ccaagggacg cacaactcct
    27421 tctacttttc agaagagatt ctttctcaag aacaccacaa gaaatccatt gtggtcagtg
    27481 accgtgccac cctctttaat ctcttgattg gtttggatgg ttataccatt gcgacaggga
    27541 ttttgaacag caacctaaac ggagacaata tcgtttctat cccactggat attgatgacc
    27601 cgatcgagct ggtctatatc cagcatgaga aaaccagcct atctaagatg ggcgaacgct
    27661 ttatagacta tctcctagaa gaagttcagt ttgatagttg agaaatgata agaaccaata
    27721 tgtaggctag caacaacctg cacattggtt ctttttactt ataattaaaa gtttcccctg
    27781 ccaacttatc agctagcttg ggaaagagag tataaaactt atgggctagg ttcaacaaaa
    27841 tcgggagatt gagttctcgt ttgttttttc ctataatctt gacaatcttt ttagccactg
    27901 catctggttc tagcaggaag cgatcaaccg atttaagata agttccatct gggtcggctt
    27961 ggtcgaaaaa tcctgtacgg attggtcctg gattgactgt tgtcacatag actccatagg
    28021 gcataagttc gagtcgcaga gcatttgaaa aaccaatagc cgcaaacttg gtcgctgagt
    28081 aaagactaga cttgccagta gctattagac ctgccatgct gacgatgttg atgatatgcc
    28141 ctttgctgct ttccttcata cgagccgcaa ggtgacgaga cagattcatc agggcaaagg
    28201 tattgacctc aaacatctgg tgaatatctt tatcagcaat ctggtcaaat ccctcaaaaa
    28261 tcccgtaacc agcgttgtta atcaagacat caatcttgcc atagcggaga taaagatcag
    28321 ttaccagagc ttctagggct gaatcgtcgg taatatcaat ttcaatcaat tctgcatggg
    28381 aataatttcc gtagagttgg gctaattttt ccttatttct accaagcaag atgagttggt
    28441 cattgggcag gagtttgacc atttcttgag ctagaccacc gctagctccg gtaatgagaa
    28501 tagtaggcat acttatcctt tctgtgactg ctagatttcc acttcttcca agtctttgac
    28561 cacatggaca ttttcaaaaa ttgtggcagc gtctttcttg agtttgctaa tatcttttga
    28621 gaggaaacgg gcactgatat ggttgagtag gaggcgtttg gcacctgctt ctaccgctac
    28681 ttgtgcagct tgcatattag ttgagtgacc atggttacga gcaatttttt catcaccctt
    28741 gccataagtg gactcatgaa ctaggacatc tgcattgaca gccagacgca cactggcacc
    28801 cgtttttcga gtgtctccta aaatagtgat aatcttacct ggacgtggcg ctgagatata
    28861 gtctgctgcc ttgatttcag ttccgtcttc caaaacaaga tcctggccgt ttttgatttt
    28921 accaaaaagc gggccgaacg gaacaccagc agccttgagt ttttcagcat ccagcgtccc
    28981 ttctagatcc ttttgcatga cacgatagcc aacacagaaa atagtgtggt ccagctcctc
    29041 tgcatacaca gtgaatttat cggtttcaag aattttaccc agagaatctt ggtcaaactc
    29101 atggaaatga atgcggtagg gcagacgaga acctgacaca cgaaggctgg ttaagacaaa
    29161 tgacttgatt ccttgaggtc cgtagatttc caaatctgtc tgctcttcat tggcctgaaa
    29221 ggcacggcta gaaaggaaac ctggcaaacc aaaaatgtgg tctccatgca gatgggtaat
    29281 aaagattttg ctgaccttac gtggtcgaat tgtggtttcc agaatgcgat tttgcgtacc
    29341 ttctccacag tcaaagagcc aaacttcgtt aatctcatcc aaaagtttca gggcgagact
    29401 tgaaacgttg cgggctttag agggctgacc agcccccgtt cctaaaaatt gaatatccat
    29461 tcgatacttt ctaattaatc aatatataac atggctgtgc ggttttccga tcggaaatag
    29521 cgtttgccag aaaaagcagc agcttcttgc aataaatcct cttggctgta gcctttgaga
    29581 cgttttcgac catcagccaa tctttccaaa tcagtcaaag ctgtgagact ttctaggctg
    29641 ataacttcct cgtcctcgac aggcttcatg taaatcttac cagactcttc aaagactaat
    29701 tgatggggga aaatttgcgc aatttcaaag agcaagtcat ccgagatttt ctcctcattt
    29761 tcaaagaaaa tccgaccaag gccgtcactc tcataacaaa aaccaaagga tttaccagac
    29821 agattaagcc gaataaaagg cttattttct agggtgaaac ttggctcagt attgtaaaga
    29881 ttcagttcct gactgagttc tgcaaaataa tccgtcgcag cctgaggact ctttttctga
    29941 tagagttctg caaagtaggc attaacaaca cttggcggag gtgtaataag tgttaactgc
    30001 tcctgatctg ttttaccagc tagaagctga tccagataga ccttgtccag acttgtataa
    30061 cctccatact ttagagccaa agttttaata tcagtcataa aattcttcta acctccattt
    30121 atttttctcg gaaatgtagc ctgtaatcac ttcgccgtct tcctgataat cacgttcttc
    30181 cagaattgca acactctcta aatcatgaat cttgtaggac tttgaaaaag gcactcgcag
    30241 ggtaaatgct tcaaaaattt ccttaatctt atctagcaat aatgcttgca agttttcacg
    30301 actgtcctca gacttggcag aaatgagggt atatggcgtt tgggtaggcg tgaaatcctc
    30361 caccaaatcc gctttattat aaagcgtcaa gtgaggaata tcttccatgt ccaggtcttt
    30421 catgatggag agaaccgttt tttcatgctc ctcgtggtaa ggattgctag catcgataac
    30481 atgaaccaga aggtccacat gcttgctttc ttccaaggtt gacttgaaac tggacaccaa
    30541 ctctgtcggc aaatcttgga taaagccaac ggtatctgtc aaagttactt ggagattgcc
    30601 tcccagatga atactcttgg ttgtcgcatc cagagtcgca aagagctcat ctgcttcata
    30661 ctgggtctta ctggtcaaga tgttcatgat agttgatttc ccagcattag tataaccaat
    30721 caaaccaatc ttaaaagtgc tagactccaa acgtttttct ctgacagtcg cacgattttt
    30781 ctcaaccacc ttgagctggc gctcgatatc cgtgatttga ttgcgaacgc tacgacggtt
    30841 cagctccagc tggctttcac caggaccacg ggaaccaatt ccccctgcct gacggctgag
    30901 cataatcccc tgaccaacca agcgaggcaa aaggtatttg agttgggcta ggtggacttg
    30961 gagcttccct tcatggcttc gagcccgcat ggcaaagata tccaaaatca actgcatacg
    31021 gtcaatgacc ttaacaccga gaacttcctc tagattgaca ttctgccttg gggtcagacg
    31081 attgttgacg atgacagtag tgatttcttc tgcatccacc ataagcgcaa tctcttccaa
    31141 cttaccagag ccgacgaagg tcttggaatc atatttttca cgtttttgtc tgtagctatc
    31201 tacaacgact gcccctgccg ttttcgctaa actagccaat tcttccatgg agaggtcaaa
    31261 actgtccata ccctgcaatt ccacaccaat cagcaggact cgctcctctt ttttctccgt
    31321 ttcaatcatc taaaaactcc tctatctggc ttaaaatgcg gtcttgtaca ccagattctc
    31381 caatctgata aaaggtgacc tgcatgcgat tacggaacca ggtcagctga cgcttggcaa
    31441 aacgacgagt cgcctgttta agactctcac tagcttcctc caaggtctgc tctccacgga
    31501 aataaggaaa gagttcctta tagccaattc ctttagcagc ctgtacatta ggggaatggt
    31561 caaacagcca cttggcctca tccaaaagcc cagcctcaaa catcaaatcc actcggtggt
    31621 tgatacgctc ataaagttga ctacgttcat catccaagca gataatcagc ggttcataca
    31681 aggtctcttg attttccaaa tcctgaccaa aatgggcaat ttctaaggca cgcatagcac
    31741 gacgacgatt aaactgggga atctcaaggc ctgcttgatc caccaaatgg gctaattcct
    31801 catctgaata tggctccaaa ctagctcgat aagctaaaat ctcctcatga ggagtctccc
    31861 cacctaggtg gtaaccttct agcaagctct ggatataaag tccagtccca ccggcgataa
    31921 tggctagctt gccacggttg tgaataccct caatagtcat cttagcttct gaaacaaaat
    31981 caaaagccga gtaagactcg gttatctctc taacatcgat taaatgatga ggaacagctg
    32041 cctgctcttc tggactagcc ttggccgtcc caatatcaag tcctcgatag acttgctggc
    32101 tatctccact aaccacttcg ccattaaaac gctttgcaac ttcaatagct agagccgtct
    32161 ttccaacagc agtcggtcca acaatcacaa ttatttttgt tttcatcttt tttccttgaa
    32221 aaattcccat tttttcgtta ctattattat aacacaaaaa ggtcagtcag aaaaatgtga
    32281 cctcttgagg aggctggctg attgagaata taaaggagga agactcatgg ctaaaggatt
    32341 cgctaaaggt cttgtaacag gtgtcgcagg aactgtcgct gccgttgcag gtgcagtata
    32401 cgcatttaaa aagaaagtaa tcgaaccaga agagcaaaaa gcagctttca tcgaagaaaa
    32461 ccgtaaaaaa gcagctcgtc gccgcgtatc acgttaagaa acaaaagaag ttgggattat
    32521 tctcaacttc ttttttctat tcttttaaat agctaggtca aacttcaact gtggcttaac
    32581 agggtcataa tccaccaact caaaatcttc tgctttgata tcaaagaaat tagtcccatc
    32641 aggaacattt aaaaccaagc gtggttggca gtttgacggc tcccgacgga gcaattcctg
    32701 agcttgttca aattgattat catagatatg gaggttgttg atgaagtaga agaacttccc
    32761 aaccttccag ccaaaatgtt tggcaatcat catctgcaaa gccacatact gcatagcgtt
    32821 gatgtggtgg gccaccagca tatcattgga gcgctgggtc aaggtcgcat ccagatagat
    32881 ttccccatca acacgccgaa catcaaacat ggtctgaaag gcgcacggga gcagcccatc
    32941 tgtttcttcg aaagcttggt aatcccagag cgaaataata ttgcggcggt tccaaggatt
    33001 ggtttccaac tgtttgagaa gcttattgat aatgtcgtgt ttcttaacaa cggcaccata
    33061 gcgctcacca atggttcccg tgtctccaac ttcccagtca ttccagtagt gaacattgta
    33121 cttgtcatta agcacttcta agctatttga ctggtcttgg taaatccaga gaacttcttt
    33181 gatggcggat ttgattgcaa tgggacgcaa ggttgtgata ggaaattctc ctttagataa
    33241 gtcgtactcg gaaaaggcac cagttacata cttggaatta gcaacagtcc catccttgta
    33301 cttaggacga gcctgctctg agaaaacacc ttcctttaga atgcgttcaa tattctcttt
    33361 aaaaatcgta tctgcttttg tcatttcgtt tcacctcatt cattgtccta actagtatag
    33421 cataaaaaat aaaagaggaa cattactaac tctaggttag cattttcctc tctcattatc
    33481 ttattgcaat acaagtgatg ctgctccgat aactccagcg tcatttccta gagttgcaag
    33541 agctaattta gtagatgtgc gtacttgtgg gaaactattt tcatcgtaaa ctttttgaac
    33601 accttgtaga aggaattctc ccgcagctga cacaccacca ccgatgacga ttgttgatgg
    33661 gtttaggatt gaaccaatgt tagcacaagc gattcccaag taacgtgaga agttacggta
    33721 aacaatcaaa gcaaggtcgt ctccttcttt tgcgagatca aagacagtct tagcagttac
    33781 ttcttctccg ttatcaatca agcgtttcaa ggctgcatcg ccttcgtatt catcggcata
    33841 gcgacgagtc aagttgacaa tccctgttgc tgaagcaact gtctcaaggc agcctttttt
    33901 accacaagta catgagattg gttggtcaaa gtcaacagtg atatgaccaa gttcacctgc
    33961 tgcaccagca acaccatgaa gcaatttgcc ttctgcgaca ataccaccac caacaccagt
    34021 accgagtgtc ataaagacaa cgtctggttg gttatctcca gcacccatcc agcgctcacc
    34081 aagagctgct acgttggcat cattatcgat gaaaaatgga atgcccaaag ctttttcaat
    34141 cttttgtttg attggttgaa gggttttcca gttcaagttg taggcaccga taacagtccc
    34201 tttgtcacgg tcaaccacac ctggtgatcc cattccaatg ccttggaagt ccgctgctgc
    34261 caatccaagc aagtccaaac gatgttgaat agactcaatc atatcatcaa cgatatgact
    34321 tccctcatcc aaaatgttgg tcttgattga ccattttcct tggatttctc ctgctgttgt
    34381 taagattgca aatttgatag aagttccacc aaggtcaatc ccaataatct tttgactcat
    34441 catattctcc tttttcattg tgtagtaatt gaaaatgctt acagtactag tatatcaaaa
    34501 tccattcact tatgcaaagg tttgcgtgaa tgaattataa ggaatttttt cgcctaccag
    34561 tatctgttaa tcatctaaat gatcaatggc atattgagct gcatcatttg aaaatttatc
    34621 aaaatcagaa gttaattgtc tatacatacg tttttttgac atgtggaata acgaattata
    34681 actttttgcc tttcctaaag cagcagaata ttcactattg ctatcattac tagaagaagc
    34741 tgtacttgct tgaacttcct tccaaactcc gtcagcgcca acataataac gtccaccatc
    34801 aacccattca ttgacagcca ttttaccatc cgattttaga tagtaatttc cttgccatgt
    34861 actgtaagca taagaaccat ctgatgtcaa ataataccaa gcttgatagg tggcatcata
    34921 aacccattca cctttagcca ttttaccatc tgatttcaaa tagtagtttc cttgccatgc
    34981 attgcgagca tatgaaccat ctgatttcaa gtaataccat gcttggtaag aagaatcata
    35041 aacccactca ccttgtgcca ttttaccgtt tgatttaagg taataagctc cttgccatgc
    35101 attttttgca taagaaccat ctgatttcaa ataataccaa gcttgataag aagagtcata
    35161 aatccattca ctctgtgcca ttttaccatc agctttcagg taatagcttc cctgccatgc
    35221 atttttcact agatttccat ttccatcaaa gtagtaccaa gcgccgtcct gcttaaccca
    35281 accacttgtt gttgctgaac ttgtgttgat ttgaatagcc gttgactgtt ttgctttaaa
    35341 agcaccctta ggagcatttt tcaattcgca agccacacca tcatgatcac ggtctaactt
    35401 ggcagaataa ccaggttctc cctcgtgaat atccgaatag ccattcgccc aagcttcctt
    35461 acagctcgaa aaatggatgt tttcttccgc caaaactgat tgtgaaaaca aggctaaaat
    35521 tggcaacgtc accagactca tttttgaaaa tagacgttta ttcatttctt tctcccataa
    35581 ttatgatatc gatttcaata ttattttatc aaacttattt cagcaattca aggaaacttc
    35641 tggtcttttc tacaaactcc tttggttttg ccttattcaa gacatgaggg ccatcaggaa
    35701 tgatctgaaa ctgcgaatct gttaacagtc tatggagagc tttcatagaa ctaagattcg
    35761 gtttatcttt gctgccacaa attagtaagg ttggataagg gtaagttcct gctatatccg
    35821 ttaaatcaag tgtcttcaac tcctcagaaa ctccgaccat aagagtcttg tctgctccct
    35881 gtttttcaaa tactcttttg ggaagtagtt taaaaatcag caattgaaga taaaatagga
    35941 tattccctgc taatttaagc gggcatcctg acagaatcaa agctcgaaga tttggtaaat
    36001 cgtaactgga aagttctagt gtcagggcag cacctaagga caatccaatc aaaacaaaag
    36061 gttctgtctc ttgagctagg tgctgataaa ctcgctcttt agcttgttga tagttactaa
    36121 ctccagaagg aaataactcg atagcctcag aaggataatc tgtcagtaga ttccgaactt
    36181 ctttccaaga ctctgctgac tgccctaacc catgcaaaaa tattaatttc atctagttct
    36241 cctcaaggct taattcatac aagcctctca ctgcattaca gccgtaaata gcttctgctt
    36301 gggttaaatc tgccaaggtc aagactttct cttctacctg tcctgtttct agcaaatgct
    36361 gacggtaaat tcctggcaag attccaagtc ggataggcgg tgtgtagagt tttccagcga
    36421 ttttcagaac caaatttcct atagaggttt caagcagttc tcctgactta ttgtggtaaa
    36481 tcttctcttg ttctcctagg ctcaaatgcg gtcggtgagt ggttttaaag taggtaaagg
    36541 attgattcaa agcagcttcc tgaagacaga cttgggcctg acaaaagctt gtactgagag
    36601 gggttaatac ttgacgattg acttctatct ctccagattt gctaaggctg attcgcaagc
    36661 ggtaatctcg attagcttca caatcctgac actcttcctc aatcttgtgt cccaagtctt
    36721 ctgcatcaaa aggaaaagca aaataacgac tagcttttct cagcctttcc agatgttgtt
    36781 cttcaaacat cagttgtttt tggctgattt ttccagttgt aattaattgg aagcgagctt
    36841 gtttacgata gagaactgct gccttttgat gaacctctcg gtattcagat tcccatgtgc
    36901 tatcccaagt aatccctccg ccaactccat aaatggcttg acctttgtga agttgaatgg
    36961 tacgaatggc cacattaaaa atccgtcgtc catttggaag caagagacca atcgttccac
    37021 agtagactcc acgcggttga ggctccaagt ccttgataat ctccattgtc gcaattttcg
    37081 gtgcacccgt tatggaacca caaggaaaga gtgagcggaa gatttcaaca aggtccacat
    37141 cctctcgcaa ctgactcttg atggtcgaag tcatctgcca aacagttgaa tactgctcta
    37201 cctgacacag acgctccacg tgctcgctcc caacttcaga aatacggttc atatcattgc
    37261 gcaagaggtc cacaatcatc atattttcag agcgattttt gggatcctgt tccaaccaac
    37321 tggcctgttc aagatcttct tggtcagtta ccccacgctg agtcgtcccc ttcattggtc
    37381 gtgttgtcaa ctcgcgatca ttttgctcaa aaaagagctc tgggctcatg gaaatcactg
    37441 tcatctcgtc atgttccaca taggcattgt agcccgcctc ctgctctacc accatacgat
    37501 tgtagatggc aaaaggattg gcatttaact tttgcttaag ttggacggtg tagttgacct
    37561 gataggtatc tccctgccgt aaatgatggt gaatttgggc aatggccttt tcatagtctg
    37621 ctgcagacgt tacttcctgc caatttgagg gcaaatcaat atcctcataa gtcagaggaa
    37681 taggggaagt ttctacgata tcatgaacag taaagtaaag caggtactct cccagtaggg
    37741 gatccttgtg aactgctaat ttttcctcaa aagcaggtgc agcctcgtag ctgacatacc
    37801 ccaccacata ataaccttgc tcttggtagc tttccacttg tgccagcaaa tctgccactt
    37861 cttctacatt tctcgttttc aactctttaa taggctgggt aaaggtatat ctctccccca
    37921 aagtcctaaa atcaatcact gtttttctat gcatacctta agtatagcat aaaataagaa
    37981 aaccctcatc cgcaaagcag atgagagatt tcaattattt aaagattgaa gttttaaagc
    38041 tatttgtttg ttgaagaagt ttcttataaa cagcttcttt taatttaact gtattattca
    38101 tagatactgt tttattaccg tttgcttctt gtttaagagt ttcggcatct tttttaacag
    38161 cttctttaaa caatgtcagt aaatcatcgt atgatgaaac ggaagaacca tttacttcga
    38221 atgttgttaa tcctttcgtt gctttatctt taacttcttt gaagtaagct tttttaaatt
    38281 cttcaatagt attaaatgta ttgttagata ttttcttgat aatatattca tcacttagaa
    38341 cagactcacc atctgtttta gattgttgtt tatatttatt tgaagcataa cctaagaacc
    38401 cattttcgta tccgtagtaa ccccataatc taaaagcatt atgtttgaat gaaacagctc
    38461 caggagcacc tttactagta ttacctccgt agataccggt catcattcta acacctacat
    38521 aaggtgattg atcgttatag ctaattgctt cgggtttata gataccatta cctggattgc
    38581 gattagtcat taattgttga tcaactaaat cattaacaga ttgaatattt aattcatttt
    38641 tctcttcttg acttagattt cgaattttat cccattgatt taatttattg ttatcacggt
    38701 attctctatc tatttttttg aaccatgcac tatttaaatc tttattttgt tgagaaatca
    38761 cagattcagc ctcaatttca tcaagaagag ttaaagtgtc attataaccc ttcatatatc
    38821 tattaatatc ttctcgtgtt tttagagttt ttggatctgt aatataccac tgattcccat
    38881 catttttgcg tttaaatacc atattaatac ctaaagaacc aaactcatca aatccactac
    38941 cagtaacagg agtttgtagc ataccctgag catatgcttc agcatcagta ccttcacggt
    39001 gtccaaagcc acctaagtaa atcgcacggt cgttgacgtg tgttgtttca tgtgtgtaaa
    39061 ctgaaatacc gtattcacca accatttcta aatgaacata ttttacatca gttctaatat
    39121 catcagagtt aggatatata gcagcataag ctcctgttcc attataatta taatacttat
    39181 ccataggacc aaagaattct ctaagaggag tatatacttt gtcggtatta tagcggccat
    39241 atttttcaac ccatccacca ggagcgttat aaccttccca aataggaata acagcatctc
    39301 ttagtagtcg ttgtttaacg ttatcagacg ctagacgata ccagaaatca taatagtttc
    39361 tataaccatc tgcagctttg ttaacgatat ctttaatatc ttctaatgat tttttaccta
    39421 atcgctctgc actaccaaag gcaattgcat tataatttga aattaaataa agatgtgctt
    39481 tatcaatatt cagtagtggg agtatagtat ttctaaggtg acttcgtttt aaattatcga
    39541 atgcacgatg tttagaattt ttaatttctt cgacctcaga agcgcgttct gcgatgtaga
    39601 catggtcttc tgtagcatca ataaaccaat cgttcatatt gtctatattt gtgaacaatt
    39661 gtctattata atttaaaaat gcatctaaat tacctgattt agtatattta gccaatactt
    39721 gaccgaatgc gtcgaatgta cgtgaacctt taatgttgtt ctctttagaa ccgatttcaa
    39781 ttaatctgtc taatacgcta actttttcac catagaaatc tggtttgaat agcattaatt
    39841 ctttaatatt aacatcacca aatttaactc catagtaacg atttaggtaa gttaaaccta
    39901 gtaataaagc tgctttgttt ttctcgactt tatcacgaat catttgacga gcagctggag
    39961 aatcatttag ttgatgttct tcgttttgaa ctaattttgt gattaggttt gttaagtttt
    40021 ctttaacatc tgtgaagctt tcttctaaat ataaatcttt gattgcatta actctatagt
    40081 cacctaatcg atttagatgc tgatacatcg tttgagactg aagctctact gattctaaaa
    40141 tagattttat atcattaaca agagtagtgt tatctttttg aacgatatta ggtgtatatt
    40201 taattcctaa gtcagttata gtatattctt ttacattact taaaccttca ctgctagaag
    40261 acaagttaaa gtaatctttt gtaccgtccg catagtgaac aataatttta ttagcttcat
    40321 ctaggtttgt gataaactca ttgttgttca tcgcggtaac agaaagaact tctttagtat
    40381 ttagatggtg ttctttattt aatttattac cttgatatac aatataatct ttattgtaga
    40441 atggtattaa tttttcaaga tttttatagg cttggttata ttcagcgtta taatcttgaa
    40501 tactagaata ggctttttct tcattaagtt ttgcaagagg agatagatca ctttctaatt
    40561 tatcagcagt aatattgaaa gtagtaactt tagcatcagc ttgttcttta gttaatttag
    40621 taaatgtttt agatttccta aatgatctat tacctgacga atatccctct accgcatata
    40681 aatcttttat atgagcacta gcataatcag aatcatcaac gtcgttagag ccgaataact
    40741 cctctccacg gataatctta gcatagctga cagaattact taccgtacct acaggccaag
    40801 tcttacttgc tattgctcca acttctactg gatttgaaac atctatttta ccttttacaa
    40861 ccgactcagt taggagagct tttgtaccaa taagatggtc tagagttaat ccataatcta
    40921 ctttaggaac taacaagctg gcgcgtgttt tgtttcctgt aatagtagca tcaacatatg
    40981 cttttctaac aattcctcta tagtttgtac ctgcaattcc ccctgtatga gagccatttc
    41041 cacttgtaga gtgtagtttg ccaaagaaag caacattttc aatacgagtt ccatcattca
    41101 tattatttac aaatccagca acattattac gacctgaaag tgtgcctgta attttgacat
    41161 ttgtaataac tgaagaacct ttcatagtat tggctaatga tgcaatatta tcttgaccag
    41221 aacgttctat ctctacattt tcaaaattca cattatttat cgttgcgttt gttatcacat
    41281 taaataatgg atgttccaat tcagtaatag caaattgttt tccttcagaa cttaaaagtt
    41341 ttcctgtgaa ttctttagtg atatatgatt ttccattagg aacaacattt ctagcgctca
    41401 ttgattgtcc cagacgatat tcttttgaag gatcgttttg aatagcttcc actaattctt
    41461 tgaaattata atatacatta tcttcgtgga ctttaggttt ttcaatatag tgaacgtatt
    41521 cttcttcaaa tttattatca gcagttctag agactaaatt gtctgcgatt gctgtaactt
    41581 tatatacagg tgttccgtta accgtagttt cttctatatt tttaacagct agtaatgtag
    41641 ttttctgatt atttgaagtt atttttaaat aataattgct cttatcatca ggaatagttg
    41701 ttatcagtga ttcattagtt tcttttccat tttcgtattt gattaaatct gtacgtttaa
    41761 tatttttaag ctcaactttt ttaagatcta attgaatatt ttgattttct agagtttcag
    41821 tttcttcacc gttacctctg tcgtaaatca tagttgtaga tagggtgtat tctttgtagt
    41881 actctaggtt cttaaatgca gcgcttatag tttctgttgt taccttgtca tctgtaagga
    41941 ctacagtatt aataacttct tctccttttt tcaattcagc tgtgattgat ttgatttttg
    42001 ttttgttttg attttctaga gtatacttag caacagcttc acgttccaat attttcttat
    42061 cggtactagt caatgttaat attggctttt cagataattc aaccaatttt tcaatagttg
    42121 cagttaattt ttcaacagct tcgttaactt cactttgttt agcatctgta ttagctgcaa
    42181 ctttttcagc ctttgtaact tcagtttgga ggttttgcca acttctatca ctgtaatgtt
    42241 cttttacctt tgtttttgca tctgcaatcg tattgtttaa ttcagtttta tcaacgttta
    42301 gagcgtcaat agccgtttta agtttatttg tctcgctatt tacctcaggc tgttttacag
    42361 gctctgaagc atagacacct tttgcagttt ctaaaacagg tccaagagca ttgtaacttg
    42421 ctgtagaata atcagtagga gaaactgaac tagctttatc aatttgatta tttaactcac
    42481 ttttatcaac tggttcttta gtaccaatac cctttatttt atcttctggt ttcggtgttt
    42541 cctctacagc cttctcttct tcaggaactt ctggttgctt ttctggctca actggtgccg
    42601 ttggtgcctg ttcgtcttct cttggcgcga ctggttcacc tgcttgttca acttttggtt
    42661 cctctgttgg ttctgtttgt ttttctacag caggcgtttc aacttttggt tgttcaatag
    42721 attgattaac agtctcctct tttggttcta cagtttcttc agccttggta tctggagttg
    42781 actcttcttg tttcggtgtt tcctctacag ccttctcttc ttcaggagct tctggttgct
    42841 tttctggctc gactggtgcc ttttcgtctt ctcttggcgc gactggttca cctgcttgtt
    42901 caacttttga ttcctcagct ggtttgtctg atggttgact ttctggctta actgctactt
    42961 tttcctctgg ttttgactca acttctccac ctacttcttc aactggagct ggttctgctg
    43021 aatcttcttt cccctcttct actttaggaa gggtgtcgtc agtaggtttt acctccgatt
    43081 ttggttcttc ctttggactt tcttctgttt taggtgcttc ttcttttgga gcttcctctg
    43141 tctctactac ttggttttct gtcctagctt gctcctgatt tgttattgat tgaggagtct
    43201 caacttcgac cacagtcacc tctccaggtt ttgctgaggt ttcttctaaa acagtgtcca
    43261 agccaagcgt tttgaggatg tcacctgata gataaccaac atagcgatag ccctccattt
    43321 caacaacacc ctctcgacta gccagcgcta gggtcgcaac tgggtctaca gcccctgcac
    43381 taggaagaac taccaatccc atagctccaa ctagaaagac gctagcaatt ttctttctct
    43441 tgtagattaa aagcaagctc ccaacagtca gcaaaccaaa agctgtcaaa acagatgctt
    43501 ctgtccctgt ttgaggcaac tgatcttttt gatacaccaa accatataca acttcattcc
    43561 tgtcaggctt tcctgtctga attaaatctt tagcttcttg tgaaataatc tctttattta
    43621 catagtgata ggtggctgcg tccactacag aaggagccat caaaaggctt ccaagaaata
    43681 cagagcctac aactccctta atcttacgaa ttgaaaaacg gtctttttta aacactttta
    43741 tctcctttat tcattctcaa aacttcctaa tagcatcttg cggatagtgc gcacgcgcac
    43801 ctccgattaa ttttggacga ctagccagtg ccgttacatg ggcatgacca atctctctca
    43861 aaatagggcg aatcggaacc tgaacatgct tgacatgcat tccaattgca gtgtctccga
    43921 tatccaatcc agcatgagcc ttgataaatt caacctcaac tggatcctgc ataaacttaa
    43981 aggctgccaa ctgccccgaa cctcctgcat gaagagtagg atggacactg acaatttcca
    44041 gaccaaactg ctctgccacc tgacgttcaa caacgagagc ccgattgaca tgctcacaac
    44101 cttgaactgc taaatggata cctctactac ctagaatatc caagatagtc tccactatca
    44161 gctcaccaat ctcttgactg gattctttcc caatatgacc acctagcacc tcactagaag
    44221 atagacctaa aacaaaaagg gccccctgct tcaaattggt cttttctaaa acatcttcca
    44281 ctacctgacg tgtttctctt tgaatctgtg tctcgttcat ctctgttacc tctgttgtca
    44341 ctcttctatc ataccgtttt ttcttgtttt tagcaagata gacaacctag aaagtttgcc
    44401 caattacgca taaaactccc agaattgact gggagttagc tagtttctat tctatttata
    44461 tatatttcaa ctttcgtccc tttttggggt ctagaatcaa tcttcatatg gtaattggct
    44521 ccaaaatgaa gtttgagccg ttgatcgaca ttttgaagac caactccccc acgtttgagt
    44581 tgactttgac tactatcacc agcatcttgg aagccaacgc catcatcctc aatacggatg
    44641 accaatcccg aatcctgttt ctggacagaa agtttaatat ggccctgacc ttccttttcc
    44701 ttaatgccat ggtaaagagc attttctaca aggggttgta ggaccagctt gggtaagact
    44761 aaattatcaa aggcaacatt ttcattaatt tcgtattcca gcttatctcc atagcgttgt
    44821 ttctggataa agagatactg gcggacatga ttgatttcgt cagagagaca aatcaagtcc
    44881 ttgccttgat tgagcgccaa gcggaaatag gttgccaagg acttggtcac ctgcaccact
    44941 cgctgactat catgaaattc agccatccag atgatggtgt ccaaagtgtt atagaggaaa
    45001 tgtggattaa tctggctcga aagggcttga agttggtact gacgggtcgt ttcttcctgg
    45061 ctacgaatag ctaccatcaa ctgatcaatc tgatccaaca tagcattaaa ttggcgagtt
    45121 acttctctca gttcataggc accaacttcc ttggcacgaa gattttgagc accagaagca
    45181 atttccaaca tggtttctct caaatccttc aaaggagcaa tccagcgttt aagactgaac
    45241 cacactaagc agagacagac aagaagagat gtgacactgg ccccaagcaa ggtccacaag
    45301 agctgactcc gaacctggtc taacttttcc aatgatgaca cgccaagcac cgtccaatca
    45361 gttcctgcaa tcttctcttg actgacgtag gatttgtgac caggagtata accctgacct
    45421 gtatcgatgt agggtttcat agcctccatt ttgctagacg aactataaac tgtgtgttga
    45481 ggatggtaga caaattcatg gttttcattg ataatgaagg caaagccctg ctgccccaac
    45541 tggagttgat tgagataggc ttccagagtt tcataagaaa tatccaaacg aagcacacca
    45601 agattggctc cctttgcatc aacaagttct tgagtgacag aaatgaccca ctgactatct
    45661 gatttacgag ctggagtcaa aacaggcata gctccctgat gaatggcctt ttggtaccaa
    45721 tcctcagcca tcatatcaga ggaagttttc atctgcacac tgtcatctgt agaaatgacc
    45781 tgaccagatt tggtcaccag cacaacagtt ttcaagtcct tatctgactt caagatggtc
    45841 aaaaacaaat ctcggattcc ctcgaccttg tcttgactgg gattctcagc ataggccaga
    45901 acatccgtct gctgggtcaa accagtcgag gtggtttcta gttttttgat ataagactga
    45961 ataaagtggc tagtctggct gatggtcgtt tggctgttgc cctcaatggt ggcctcaatg
    46021 gctgaagaac ttgattgata gtagaaagtt ccaaccagag ctaggagaat gagaaagacc
    46081 agaaagatgg aaataaccat tctaactaaa agagaagaac gcttcatcgg tcttctccct
    46141 tcttaaactg acgaggtgtc acacctgcaa tctgcttaaa acgttgggta aaatagttca
    46201 tatcttcaaa accaaccttc tctgcgatct cataaatctt cagatctgta gttaaaagca
    46261 agagcttggc ttgtttaaca cgttctctca ccagataatc ctgaaaaggc aagcccaact
    46321 ctttcttaat caaggaactc agataggtcg gactaaaacc taagtcactg gctaaagact
    46381 ttaaactaaa ttggctatca gccagatgag actggatttt ctgggccatg tttccttcaa
    46441 acctattagt caataaatct tgtaactgct cttctttctc ttccttgtct agtttttgtt
    46501 tgattttccc caacatttcc tcaatatcct gacgagaaaa gggtttgagc aggtagtcgt
    46561 ccacacctag tttgacagca gacaaggcat aatcaaaatc atcgtaacct gttaaaaaga
    46621 ccaaatgaac ctgaggatag gtttctcgta ccagactggc caactggatg ccatttagat
    46681 gaggcatgtt gatatcggtt aaaatgatat ctggcacctg cttttggatc aattcccaag
    46741 cctgccttcc attttcagcc tgaccgatga tttccatatc gtaggctgct acattgacca
    46801 gtttagtcaa accttgtctt accagatatt catcttctac gattaagatt gtgtaggtca
    46861 tgctctgctc ctttaccact tactagtatc agtatagcaa aattctcctc taactgctta
    46921 ggaaagacct cttatactca ataaaaatca aaaagtaaac taggaagata gccacaggtt
    46981 tctcaaagta ccgctttgag gttgtaaata aaactgacga agtcagctca aagtatagct
    47041 ttgaggttgt agataaaact gacgaagtca gtaaccctac atacggtaag gcgacgctga
    47101 cgtggtttga agagattttc gaagagtatt aatcaacata atctagtaaa taagcgtagc
    47161 ctttttcttc catttggtct ttgggaataa agcggataga gaggctattg atacagtaac
    47221 gtaagccgcc cttgtcctgt ggaccatccg taaagacatg cccaaggtga gaatctccta
    47281 ctcggctccg cacttccata cgcgtcatat tgtaggactt atcttccttg taggtgacaa
    47341 catctggact gatgggttgg gtaaaactag gccagccaca accagactca aatttgtctt
    47401 ttgatgaaaa gagaggttcc ccagttgcta tatccacata gataccggat tcaaatttat
    47461 cccagtaacg gtttgagaaa gctcgttctg tttgattttc ctgggtaact gcatactcct
    47521 caggtgacag ggtctttttc aattcctcat cacttggttt tggatatttg ctggcatcaa
    47581 tgacaggata ggccgcctga ttaacattga tatggcagta gccatttgga tttttcttga
    47641 gatagtcttg atggtaatcc tcagccacca caaaattctt caagttttcc ttttcaactg
    47701 ctagaggttg atcgtatttc ttagccacct catcaaagac ttggttaatc acttccaaat
    47761 ccttgtcatc tgtgtaataa acaccagtac ggtactgggt ccccacatca tttccttgtt
    47821 tatttttgct ggttggattg ataatgcgga aatagtgaag caggatttcc ttgagagaaa
    47881 tttgcttggc atcataggtg acatggacgg tttctgcatg acctgtttgg ttaatcaatt
    47941 cgtacttggt tgtttctcct ctaccatttg catagcctga aacggcatcc gtcaccccgg
    48001 gaacacgtga gaaatattcc tccactcccc agaaacaacc tccagctaga taaatttcgt
    48061 gcaagtctgc gtctttacta atttctgttt ttttcactgc ttttcctcct tggctaactg
    48121 ccgccttttc aatttgcgag gcatctgtct gccctgcatt tcgtatcaat agaacataga
    48181 aaccggttat ggctagaaaa aatactccta gcaacaagaa gatttttaac ttatcattca
    48241 taagacgcct cctaggctaa ttccttcaaa gtttgcaaaa ttgcatcttt ttccatgaat
    48301 cctggatgtg ttttgaccag cttgccttct ttgtctataa aggcttgggt tgggtaagaa
    48361 cggacaccat aagtttccaa aagtttgcct gatgggtcaa ctaggactgg gagattttta
    48421 taatccaatc ccttatacca attcttaaag tccgcttcag attgctctcc cttatgtcct
    48481 ggtgacacta ctgtcaagac cacatagtca tcaccagctt ctttagcaat ctcatccgta
    48541 tctggaagac tagccagaca gatggaacac caagaagccc agaatttgag atagactttc
    48601 ttgcccttgt aatcagataa acggtaggtc ttgccatcta ctcccatcaa ttcaaaatca
    48661 gccacctctt tccctttagc tgcgcttgtt ttactagctg tctgctccgt cttcatttca
    48721 tctttcgttt ggtgttcact agtcacggac ttgcctgaac aagccgtcaa acaaaggagc
    48781 gaacctgctc caagaacaca tgtttgccat tttttcatat tgatattcct ttccatttta
    48841 ttcaaataat tgacttaaaa ttgaagcatt tccaaacaga accaagaagc ccatcacaat
    48901 aatgagaaaa ccacccactt ttttgaggat tccgagatag ggatgaagtt ttcggaaatg
    48961 tttcaaaaca taactagagg tcagagctag aagcaagaat ggtagcgcca agcccagcgt
    49021 atacaccaac atgagaccag ctccctgcca agctcctgaa ccacctgaag ccgccaaggc
    49081 caaaacagac cccagaaccg gccccacgca aggcgtccaa gcaaaactaa aggtcaagcc
    49141 caataaaaat gcctgactat agcccttacc attttgcccc tgtccttgca gttgtagcct
    49201 cttttcctta taaagcccct taaagtgtag aatctccatt tggtgcaaac caagaaggat
    49261 aataattgcc ccagtaagat attggaacca agaagcataa agcaaatcgc ctaaaaaacc
    49321 agctccatag cccaacaaaa taaatataaa ggaaattcct gctataaagg ccagagttcg
    49381 taataaacta gtaactgaga ttgaaaattt gccgctagaa gcctgagcac catccttatc
    49441 atctagtaac actcctgtat agaccggtaa caaaggtaag atacaaggag aaaagaagga
    49501 tagaatccct gccaaaaaga cacttagaaa aaagaaaata tgacccataa agttcctcct
    49561 atcattttat tgatagattt attatactcc ttccattttc gaaaaaacag ggacaatgat
    49621 aggggaaaat aggaatttaa tcagatgatt tagaaatctt ggacaaaaac tatacaaaaa
    49681 actgtcaaag cacaaaagcg catagtatca agattctata aagccttgat actatgcgct
    49741 tttgtaatgg ataaatagtt agtctttttt aaagaccgga tctttcaaac tctgcatact
    49801 ggcattgatc accgcgccta ggataacaat tttagcaatc aagataaacc aaaacatcat
    49861 aacaacaaga agaacggaac ctaaaattcg gacatccacc aaatgatgga catagtaatt
    49921 gagataacta gagaacagag ttagtaaacc taaaatcact aagagaacaa aggcactgcc
    49981 tggtagggta tagctaattt tcctgttaga tagattggga agaaaataat aaagcatgac
    50041 caagatagca aagaggaggg cgtaaatcag aggacctgcc aacccttgta aagcctgata
    50101 gataatgcca tcttttgtcc aataatgagc aagtaaagcc aaaatcatct gaccaaataa
    50161 gatcaaaaac aaggcaaacg caaagaggag ctgcaagcca aaactgacta ggagacttag
    50221 catctgatgg gaaataagtc cacgactctt ttcgacgcca taagccttgt taaaagcttt
    50281 ttgcaagaaa ttcatagatt ttgaaaaact ccataacgcc gataaaacag aaaaactcaa
    50341 taaacctgtt gaaggttgcg tcaagacttc tctggctatt ttttccacac cttcatagag
    50401 gcttgggggc aggacgtctt tcataaagcc caaaaattct cccacaggaa tctgaaaata
    50461 ggggaggata ttgaccacca ccaaaagcag ggggaaaatc gaaatcaacc aatagtaggc
    50521 tactgcgaca ctggtcaact cactatctga tgcttgataa taatgcaaaa aagcttttaa
    50581 taaaggtttg tctatcagct ctttccacca ctttttcatg tcatactcct tcacttataa
    50641 tcttatactc aatgaaaatc aaagagcaaa ctagaaagct agccgcaagc tgctcaaaac
    50701 actgttttga ggttgtagat aagactgacg aagtcagtca catacatacg gtaaggcgac
    50761 gctgacgtgg tttgaagaga ttttcgaaga gtattaacta atttcttctt accaattcca
    50821 ccatatcata cggtagggta ttggcagctt ccttcaagga atagttctct aagttattta
    50881 cattttgtcg taatttcttg gcatacttag tcgtaatcaa tcgtttttct tcgtattcga
    50941 aaatcaactt gcgctccaga taatagcctc tcagcatttc atcgatattg ttgggtttga
    51001 cacgattgat aacccgttcg acaaaggcac cactgctgat aatagctgtt tctcgaagac
    51061 gagactcctg cataaaacta atcaaagagc gtctgtagac tcccttcagg ttttccaaac
    51121 tttcaataat catctctgta ttggcaagat agagctctgc aatttggtca taatcaagag
    51181 cacggagacg gctttgctcc ttgttcttcc agctacggaa ggtctttccg agagtaaaaa
    51241 cttcatgaag gagaaaacgt aaaatcctca aggaaacaag aaaataatag gtcagtcttg
    51301 aggcaagttt acgattgatt ccttgttcta tatttttcag ataacgttgg taaactcggt
    51361 aagcacgatt gctaatgttc ccctcttcat aggcctgttc caaaccatca ctttcaatac
    51421 taagaatcaa gagtttcaaa gcagcccagt cttcttgatc atcctggttt tcttggctta
    51481 aaatgagatt ttcaatacgt ccatgataat tgtcaatagc cgcatagagg ggaagtttat
    51541 ttctggtgtc ttccaactct ttttccaact ctagcgttac ttcattcaaa atggcgatat
    51601 gcataagata atccttgctt tcttcctctt catcagaaag atgaggcaag accaagagac
    51661 ctgttaaaaa gctaacaagc gtcacacctg caacaaggaa aagcaaaaga ggatactcct
    51721 gttctagatt acttggtatc aagagaatcg tagcaatcga caccgttccc ttaacacctg
    51781 aaaaggtcaa gagaaacatg tccttcatat acttatttag ctttttcttg aggcgtcggg
    51841 ttctataggc ataatagcca tagatcataa taaaacgaat gacaaaaagg acaaaggtaa
    51901 gggcgataag agatagcaat aaaagtagag gattatagat tggattggtc aagataggtt
    51961 ctgctatcat ttccaactcc atccctaaaa tcacaaagac agaaccgttg agcataaagg
    52021 tcactgtatg ccagaccgtc tcggtcaccg tatccacttg ggcttcgagg agcgtgattt
    52081 tcttgaagcg acttgccttt aaaattccag caactacgac ggcaataata cctgaaacat
    52141 gaacttcttc tgccagaaag aaggtcacta gaggcaaact caattctaat aaaagttcac
    52201 tggcaatatc cgttgcgcgc acacttagca agaaggtatg gaggaagcgg ttggtcatgg
    52261 ctgttaaaaa tccaattaaa aaaccgccta ggattgaaaa gatgagcgaa ctgctagctt
    52321 gccccagaga aaaagctcca gttgtccaag ctgtcaaagc tacctgaaaa gccaccaaac
    52381 cagaagcatc attcaagagt ccttcgccct taagaatatt ggacacgcgc ttaggaaagc
    52441 taaaacgctc cgaaagagag gcaaaggcca ccaagtccgt aggaccaagg gctgccccaa
    52501 cagccaagca agctgccaag ggaaggctga accaaagaag atgggccaag ccacccaaac
    52561 tcagggtcga gataaaaatc actggaaata tgagataaac aatgattcgc cagtgtttta
    52621 aaatagccgt aacatctgct tcttcagcct ctcggaaaag caagggtccg ataaccagtg
    52681 ccaaaaacaa ctccgtatta aggtgaaagt cagtattggg taaaaagaga ccaatcacaa
    52741 ttcccaaaag aatttgcacc aaagggagag gcaaaaaggg caggagctta ttggttgtac
    52801 ttgagacaat caaaaccagt aaaaatagga tgaggtaaat cagtaattcc acgcacgtcc
    52861 tccttaatct tttttacaac aggattcaaa tatctccttc tgctctttga ttttttggtc
    52921 aatcttggaa cagtctttgt gctcaatttt tctctggcac cgttccattt caagagcaac
    52981 taattttttc ttgattttaa gcattttttt gctcatatgc gcttggtcta gcacgcccat
    53041 cgctcgttcg tggtgggttg attcaacaaa attctggcgc atggcatcca gcttttcgtg
    53101 taagtattgt ttatccatgt ctgtatctct ctaatttttc aatcatcact aaaaacggcg
    53161 ggttgttgac ttggtttaaa gttcggtaaa tggcagctgt gtactcttgt tggttcaact
    53221 ggatcacaaa atccaagaca gcatctctct cgagatcgcc tccttcatga ccatagtaaa
    53281 tcataatagc aattcgtcca cctttgacaa gtaagccaca tagcttttct aatgcctcaa
    53341 tcgttgtctg cggtcgggtg atgacagact tatcagctgc cggcaaatag cccagattaa
    53401 aaatccctgc cttagctttt atcacaaact ggtccagtgt ctcatggcct tgcaagatta
    53461 actgggcatt tgtcaagtca gcctgatgca aacgctcttg ggtcttttcc aaggcttgct
    53521 tctgaatatc aaaggcatag acttgcttgg ctagcttggc taaaaaaagc gtgtcatgac
    53581 catttcccat agtcgcatcc actacgacat cctcttttgt cacgacctca gccaaaaaat
    53641 catgtgccat ctcaagtggt cttttcattt tcaaactcct gttttacagc cttgcatcct
    53701 tgaacacttc cacgacgtcg catctccatc tcaatgctgt tgaggacttc ccatttattg
    53761 aggctccaca taggaccaag cagcatatcc ctaggcgcat ctcctgtaat tcgatggatg
    53821 acgatatgtt tgggaataat ttccagttgg tcacagatga ccctgacata ttcgtcctga
    53881 ctcatcaatt gtaaacgccc ctcatggtaa tctcgttgca tacgagtatt tgtcataaga
    53941 tggagcaaat gcagtttaat cccttgaata tcgttatccg tgacacaacg gcggacattt
    54001 tcaaccatca tctcatgggt ttcaccaggc aaaccattga tcaaatggga aacaatctca
    54061 atttttggat actttctcaa acgcttgacc gtttccacct acaattcata agaatgcgca
    54121 cggttaatca ggtcagaggt tgcttcataa gtagtttgca agcccaattc aaccgtcaca
    54181 tgcatgcact ccgataactc agccaaatat tcgatggttt cgtctggtaa acagtctggg
    54241 cgcgttccaa tattgattcc taccacacct ggctcattga tagcctgttc ataacgctct
    54301 cgaataactt ccaccttttc atgggtgttg gtaaaatttt gaaaataaac cagatacttc
    54361 cgaacatccg gccacttgcg gtgcataaag tcaatttcct tataaaattg ctcacggata
    54421 ggcgcatccg gtgccacaat ggcatctcca gaaccagaaa ccgtacaaaa agtacagccc
    54481 ccatgagcca cagtcccatc acgattggga caatcaaatc ccgcatcaat agggacttta
    54541 aaagtctttt ctccaaagag ttttcgataa taatcattca aggtattata agatttcatg
    54601 actttcatta taacaaaaat cacccacaat ctcaaaagcc tgactttcct ataaattcct
    54661 ctgtttctcg tttccattag ccttttttta tgatacaata tgggtatgat tttaatgaaa
    54721 ttagcatcta ttttattatt gatactgacc ttagtcgtct gcattatcct aaccaaactt
    54781 tttagattaa aaaaactagg acgaaacttt gcggatttgg cttttccagt cttggtattt
    54841 gagtattact tgattacagc taaaaccttt acccataatt tcctccctag actggggcta
    54901 gccctctcga tcctagccat tattctcgtc tttttcttcc ttttgaaaaa acgcagcttt
    54961 tactacccta aatttatcaa attcttctgg cgtgcaggat tcttattaac ccttatcatg
    55021 tatatagaaa tgattgttga attgttctta atgaaatagt cgaatcccta agcattttct
    55081 agggattttt gctttctcta caaaatagta tagacaataa cactatacaa ttttatacaa
    55141 agaaaagagt ctgggacaat agtctcttat atccaaaaag gcaacggatt tgccgttgct
    55201 tttttggatg gttacgatag tcttggtaaa atagaattgc ccaataaacc atttagaaag
    55261 gctatcccat gcatattcac tataacacaa atcaaacaac tttaccacta gaaatcagtt
    55321 ccttcttacc acaagatcat ctcgttttta ctattgaaaa agtggtgaat accttggagg
    55381 aacgtcactt ctacacctcc tatcatgcct ttgatcgccc gtcttatcac cctaaaatgc
    55441 ttgtatctac tcttctattt gcctattcac aagggatttt ctctggtcga aaaattgaaa
    55501 aatggaagag ttagtgacct tagattgttt gtttattgac agaactaaga ttgaagccaa
    55561 tgccaacaag tatagttttg tgtggaagaa aacgacagag aaattctccg ccaaacttca
    55621 agaacagata caggtctatt ttcaagaaga aatcactccc cttctgatta aatatgccat
    55681 gtttgataag aaacaaaaga gagggtataa agagtcagct aaaaacttag cgaattggca
    55741 ctataatgac aaggaggata gctacacaca tcctgatggc tggtattatc gttttcacca
    55801 taccaaatat cagaaaacac agacagactt tcaacaagaa atcaaggttt actacgccga
    55861 cgaacctgaa tcagcccctc aaaagggact gtatatgaac gaacgctatc aaaacttgaa
    55921 agctaaagaa tgtcaggcgc ttttatctcc ccaaggtaga cagattttcg ctcaacgcaa
    55981 gattgatgtg gaacctgtct ttgggcagat aaaggcttct ttgggttaca agagatgtaa
    56041 tctgagaggg aagcgtcaag tgagaattga catgggattg gtacttatgg ccaataacct
    56101 cctaaaatat agtaaaatga aataagaaca ggacaaatcg ataaggacaa tcaaatcgat
    56161 ttctaacaat gttttagaag taaaagtgta ctattctagt ttcaatctac tatacaataa
    56221 gagaatgact caaaattaaa aagctagagt tccacaattg gaaatatcta gcttttttgt
    56281 ggttgagaac tattttgtct caggctcttt atcttctatt taggacaaga gtttttcttt
    56341 ggtctttaat gataaagaag gtatcaaaat ttctagtctt cttttttacc tttagtaact
    56401 actaatcctg cactcaaacc tagaagagtt aaacctgctg ctactgctgc ttggcttgcc
    56461 gcactacctg tacttggtaa ctgggcttta ttagtttgac tagcttcact tgaatcaatt
    56521 ggttttgtat ctgctttttc tgacacttgt ggttttttag cttcttgagc tactggtttg
    56581 gttccaacca agacgatgcg gtctgtcgga acttctacca cttcacggag tttttcttcc
    56641 ttacttccat caggattaat cgctgtaaag atacgttctt ttccaacttt tccttcttgt
    56701 tctacacgag tttcacctag atacagtgtt gaatcttttt tctcaactgt cttgtatgcc
    56761 aaatcttttt caacaaattc gatttttgga agatcttctt gtacagcagc aactgtcttc
    56821 tcagaaactg gtttttcctt agtcaagtgg atacggtatt ccttgacttg ttttccactt
    56881 tctgaaacga ggcgaacaag tactggaaag ctatcttctc cactatctac cacagttgaa
    56941 gctacttgat tgttttcttc aactgagact tttggccgtt gacctttata ggtaatttga
    57001 tagtcttgac gattttcagc gaaatcagca agttcttttc catctacaag aatctttgat
    57061 tgagtgcttt cttgaggcaa ttcacttggt gcaaggaagg tcatctcaat catcgcaaca
    57121 ccgctcttat ctgctttacg ctccatacgc catctcatag ctttggcttt gatagcttta
    57181 aatgttacgt tgatttcatc accagctgca atgtctttat ccgcacgata aggaacagct
    57241 tcccaatttt ctggattgtt gaatggatgg tctgcgtcgt aggcttggta gtttgaatag
    57301 taggttggca cttcaaactc tggaccgaca tagcgttcta aaacgagttt agatggtgca
    57361 tccgtaccac tatctgcaaa gaactgaact tttccttgtg taacagtccg ttctacaatc
    57421 ttaccatttt cacggaaaat cacacccgct gatacttctg gattagaaga tggtgttggt
    57481 gaccagtttg tccaacgacg attttctgaa tgatctccgt cattgagata gtcaacgcgg
    57541 tcatgagagt ttttgtcaat atcattggtt gctgaagcaa aggcctggtt actgttttca
    57601 tcatagttag ggttatctga aagagtctca ccaagtttgt ctgtcactcg tacagtgatc
    57661 tcagcaacaa ggttactacc aaggacacgg cctcgaacag taaattgacc tgcttttgtc
    57721 agattttccg ctggaacttc ttcccattca actgtcaggt cttttgtttc gtagccgtct
    57781 ttacctgtga agtaaactgg aaccttagtc ggcaattcaa gtgcttgacc tacttgtagc
    57841 aagcgagctt gtttaaccgc agcaactggt ttatgagaaa gtaagctctt atccttagtg
    57901 aagtgcagac ggtattctcc taagatgtcg ccattttcag ctttcgcgat gacacgaact
    57961 ggctcacctt cacgaacgct tggaacgacg gtagcgagac cattgttgct aacacttgct
    58021 gtgactgccg gaacttttcc atctacagac tcaaggtagt agtctgtcaa atcagggttg
    58081 aagtttgcta agtctttgcc gtcaacttgg attcttgttt gtccttgctt ggctgccgca
    58141 acttgtttcg caaagatttg tacctctgtg atagacgttc cacgcttgtt atctgcttta
    58201 accatgcgaa tacgaacagc ataggtttca actttatcaa agctaaagtg gttcatttct
    58261 ccagccttga gttgagcagg ggcttttaga ttagtaactg gtttccagtt ggcagaatca
    58321 ttaaagacat ggtcctcatt accaacaaaa ctagggtttt taggagctgt tgggacagtc
    58381 ttaccaacat aatactcaat cacataagac ttcggtacac caactccatg gtcttcatgg
    58441 aatccgacac ttagattatc aacggagcgt ttgctcaaga tacctgaatc tccaaacaga
    58501 acaccgactg aagcttctgg attagtacga ttccagtttg tccaacgatt ggctggttgg
    58561 ttattgtagg aaatgagctt gtcattaaca tttgaaactg ggtcgcttgg atttgagtct
    58621 gaagcaaagg caagtggcaa ttctgaaccg gtccattggt cagaaatgtt tgcaccttgc
    58681 tcagtttgag cagatacgcg aacatgaagt ttagttgtta attgcgtacc ttctaagcga
    58741 ccattaactg taaagacacc ttccttagcg tattgctctg gacgaatcgc atcccatgca
    58801 accttagctg atgaaacgtg accatttgaa tcatatgtcc gaacactttc tggtaattgt
    58861 ggtgcttctg cgattggagt tgtcacactg acttcttcaa ctgaaacgat accttctaca
    58921 gagacttttg cacgcgcttc aaggtcaatt ccttcaactt tacctagtac ttcaaatgtt
    58981 tgataggagt ctagtttttc tttcggaata gcttgccaag tgactttatg agttttaggg
    59041 aaacctttgt catactcaac tgttactgtt gctggaagac ttggttcctg atgcaaatct
    59101 gtcactacat ttacaggacg gatggattgc gcaatcttct tctcagtatt ggcttggata
    59161 gtgagttcaa cttggtcttt agctccctca tattcagcgt tcagagtgac tgctcctggc
    59221 ttatgcaact caagcattcc tttacgaatt gcgacttccc cttcaccact tgtagagaag
    59281 gttactttat cagctggtaa tacagcttgc gttccatctt gatagtgagc tcgaaccgac
    59341 aatttgacag tttggtcttc tttgagactg tcagcttttt ccacttgcaa gctcaagtga
    59401 gcaatttttg gcgcttcttc aaggaattga attgcatagg tttgaagagg gccaccatct
    59461 ttaggctgaa taaagatgct cgcacgcatg ccgtttgctg cgcttgcttg aagaactgta
    59521 acagctgcat ttttagcact tgctgtgact tctggcaact tagctccata agcaagagtg
    59581 cggtattgca ttggtttttg actagtaaga cctgttactg cctcaccacc aaccgttaca
    59641 gttggtactg caggtgccgc aggattgcct tcttctacca caagggttgc atgaattggt
    59701 tgaccttcta aataaccggt cgcttgaata cgagaacctg gaattgctaa cttagcttta
    59761 tcttcttcgg caatctccca cttgtccact tcatactctt caacacttcc atcaatcaaa
    59821 acataggaaa cagatttgtc tacagaattc aagtcagtat ttggagcaat acgtttcaca
    59881 actggtagct ctgatttaag agcaatcact tctacacgag cttctacttc tcgtccgtca
    59941 gccatacctt tcaccgttac aataccaggc ttgctcacat ctactgaaga ccaggttaca
    60001 ggacgttctg cacggctacc atcactgtat acaaacggaa cagtggtagg catttcaggt
    60061 gcctctccaa taatggtctg tacttttggc acttctgtcc ccaaaacagt cttctcttgt
    60121 ccttctttct taccagtaaa gacagtgact tggttcgatt tcaagagatc agagtgggca
    60181 gtcagggtga atttccctgc ttgttcagtt gatttgacaa tggcaacacc tttaccatta
    60241 aatgctttac gaatccaaga accatctgct tgcgccttat agcgttcacg gctggcttgt
    60301 tctccgttat ctacaccgac cagttgacct tggccatgca attggaagcg aaccagatta
    60361 ttagcagttg gaaccacatt cccctggctg tcaacaattt catagtagat gtaagtcaag
    60421 tcttttccat ctgctgcaat cgcatggtct tccttaataa gacgaactgc cgctggctta
    60481 ccagcagtcg taatcttatc tcgagcaatt tccttgccag attcatcacg agcaattgct
    60541 tccaaggtac ctggttgata ggcaactttc cattcaagat aaagttcatt agcatttgca
    60601 ccttcttggt aagtccgccc atcgctggtt tgttttttat tgaaagtctt aagaccaaga
    60661 gattttccat tcaagaacaa ttctacacta gaagcattcg aataagcacg aactggaatc
    60721 ttaccttctg agtcagctac tttggatgct aattctttgt tttcccagtt ccagtgagga
    60781 agaaggtgta ccatcggttt cttcttaaca gaaacccatt ggctttggta gagatagaag
    60841 tcatgttttg gaatgccagc tgtatctacg ataccaaagt aagagctctt aacaggagtt
    60901 tgattttggt tgtgccatgg tgtaggttca ccaatatagt ccgtacctgt ccagataaac
    60961 tgtccagcat agccagcgtt gtcacggtca aaagtccatg aagcggttgc tgttttcccc
    61021 caacccacac gatcatttcc ataatctgac tgttcataat tacgctcagg tccattgcta
    61081 tgtttcaatt cacgttcagg gcgatagtaa cttccacgtg tacgggtagc tgaagatgtt
    61141 tctgatccat aaatcaacca ttttggatgc ttagctctaa gggctttgta attatcttca
    61201 gaatagttaa atccaacagc atcgagttca tcagcaattt tctcatgccc tccgctacca
    61261 ttaccgaaac ggaatttatc tgctcccatg gtaacatagc gagtcttatc aacatccttg
    61321 ataaccttaa ccaaacgttt aacagttgct aaagagtggg catcaccatt agcttcacct
    61381 atttcattac caattgacca catgaagata gcagggttgt ttttgcctct ttcgaccatg
    61441 gtacgtaggt caaaatcaga ccatttttca ccttttcgag cttctgggtg agtggcatct
    61501 ttttcaaaga aacgtccata gtcataaggt ttcttgccac cataccacgt atcaaaggcc
    61561 tcttcctgaa cgagtaaacc tagttctgct gcgatttgca aggtttgctc actagcaggg
    61621 ttgtgggttg tacggatgga gttaactccc atctccttca tttgtttgag acggcgatat
    61681 tctgctttat agttttcttc tgctccaagc gccccatggt cgtggtgcaa ggatactcca
    61741 tggaatttaa tacgttcacc attcaaagag aaaccttcat ttggagtcca gtgatagtaa
    61801 cggtaaccaa acaaatcctt cttagcatca accaattgac cgtcacggta aacacgcgta
    61861 atcaattcgt acaaggcagg tttgtcattt aaaacagtcc agagttttgg tctttcaact
    61921 tctaaaatcg catctaggct tgttgattca tgtgctttta aggtacgact cgctgtacga
    61981 actaagcctg ttacagcatg accacctcgt tcaacgattt gatattcggc tacaagttca
    62041 tggtctttgt cgtccgtatt gacgattttg ctggtcacat gagtttcaac cttgccatgt
    62101 tgttgttctt caagttttgg tgttaaaata gttgtcccat ttttctcaac atgcacctta
    62161 tctgtcactt gtaaagtcac atcacgatag ataccacttc ctgaatacca acggctactt
    62221 ggctgtttgt tgactgcatg gacagcaatc acattctcac gaccatcttt ttgaaggtat
    62281 ttggtgatat catatgagaa ctggttataa ccatttggat aatgccccac taactgacca
    62341 ttgacataaa cttgagaatc catgtagacg ccatcaaaag taaggcgaac atttttcttg
    62401 aggtcttttt catctagttt gaaagtcttg cgataccaag cttccccacc gttgagctgt
    62461 ccaccttcat tttgtgcagg agattcatga tcgaaatcgt taaagatact ccagtcatac
    62521 ggtaaatcta attttttcca cgtagatacg tctgcatcag gtttaatggc ttccttagaa
    62581 tttgcattga gtttaaagta ccaattttga ttaaaatcca ctttcctgtc ttcaatcatt
    62641 tgattcactt cttcatttgt tacagcttta gcatcttcct tgagcggttt ttcttgattt
    62701 gaagcttgtg attctatcct tggagctttt tcttccggtt tagcagacac tttttcctct
    62761 tttggagtta cggcttcatc ttctttcttc tcagatgcaa tagcctcagt tgaactaggt
    62821 tcactttgtt ctgtcctttc aactatattt ttagtttcca aagctttatc agccttttct
    62881 tctactatca ttttttcctc tttaggtttc tcagcagtat gagtaataag tgtttcatcc
    62941 gcataaacta cagattctcc agctatattt cctcctaata aaactgcaca agtcccaatc
    63001 attactgagc aagctcccac agcaaactta cgaatgctat aaactctttt ccgattccaa
    63061 tggcctttcc ccataaaacc ctccttatat tatatttagt gcagttagct actaccaaag
    63121 cccaagtggt atacatggta tgacaaccta gtttcaacaa tttacactct gcgaaaatcc
    63181 aattcaaact tcgtcagtgt cgccttgccg tagatatg
//
LOCUS       DAVFER010000006        59575 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1105170250
            SAMEA2167659-rid19724873.denovo.006, whole genome shotgun sequence.
ACCESSION   DAVFER010000006 DAVFER010000000
VERSION     DAVFER010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2167659
            Sequence Read Archive: ERR388902
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 59575)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 59575)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928716.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928716.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 04:07:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,118
            CDSs (total)                      :: 2,073
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 120
            CDSs (without protein)            :: 120
            Pseudo Genes (ambiguous residues) :: 0 of 120
            Pseudo Genes (frameshifted)       :: 67 of 120
            Pseudo Genes (incomplete)         :: 47 of 120
            Pseudo Genes (internal stop)      :: 34 of 120
            Pseudo Genes (multiple problems)  :: 23 of 120
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..59575
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2167659-rid19724873.denovo.006"
                     /strain="1105170250"
                     /db_xref="taxon:1313"
     gene            complement(307..996)
                     /gene="rplA"
                     /locus_tag="VU534_000375"
     CDS             complement(307..996)
                     /gene="rplA"
                     /locus_tag="VU534_000375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HEU1513015.1"
                     /translation="MAKKSKQLRAALEKIDSTKAYSVEEAVALAKETNFAKFDATVEV
                     AYNLNIDVKKADQQIRGAMVLPNGTGKTSRVLVFARGAKAEEAKAAGADFVGEDDLVA
                     KINDGWLDFDVVIATPDMMALVGRLGRVLGPRNLMPNPKTGTVTMDVAKAVEESKGGK
                     ITYRADRAGNVQAIIGKVSFEAEKLVENFKAFNETIQKAKPATAKGTYVTNLTITTTQ
                     GVGIKVDVNSL"
     gene            complement(1204..1629)
                     /gene="rplK"
                     /locus_tag="VU534_000376"
     CDS             complement(1204..1629)
                     /gene="rplK"
                     /locus_tag="VU534_000376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004226069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HEU1513016.1"
                     /translation="MAKKVEKLVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNA
                     RTADQAGMIIPVVISVYEDKSFTFVTKTPPAAVLLKKAAGVEKGSGTPNKTKVATVTR
                     AQVQEIAETKMPDLNAANVESAMRMIEGTARSMGFTVVD"
     gene            complement(1938..2654)
                     /locus_tag="VU534_000377"
     CDS             complement(1938..2654)
                     /locus_tag="VU534_000377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HEU1513017.1"
                     /translation="MKKRYLVLTALLALSLAACSQEKTKNEDGETKTEQTAKADGTVG
                     SKSQGAAQKKAEVVNKGDYYSIQGKYDEIIVANKHYPLSKDYNPGENPTAKAELVKLI
                     KAMQEAGFPISDHYSGFRSYETQTKLYQDYVNQDGKAAADRYSARPGYSEHQTGLAFD
                     VIGTDGDLVTEEKAAQWLLDHAADYGFVVRYLKGKEKETGYMAEEWHLRYVGKEAKEI
                     AASGLSLEEYYGFEGGDYVD"
     gene            complement(2657..3127)
                     /locus_tag="VU534_000378"
     CDS             complement(2657..3127)
                     /locus_tag="VU534_000378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HEU1513018.1"
                     /translation="MCLICQRIDLIKKEENPYFVKELETGYLVVGDHQYFEGYSLFLA
                     KEHVSELHHLKKETRLRFLEEMSLVQEAVAKAFAAEKMNIELLGNGDAHLHWHLFPRR
                     TGDMNGHGLKGRGPVWWVPFEEMTAETCQAKPDEIKRLVKRLSSEVDKLLEIKE"
     gene            complement(3129..4166)
                     /locus_tag="VU534_000379"
     CDS             complement(3129..4166)
                     /locus_tag="VU534_000379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HEU1513019.1"
                     /translation="MNQTVEYIKELTAIASPTGFTREIADYLVKTLEGFGYQPVRTSK
                     GGVNVTIKGQNDEQHRYVTAHVDTLGAIVRAVKPDGRLKMDRIGGFPWNMIEGENCTI
                     HVASTGEKVSGTILIHQTSCHVYKDAGTAERTQDNMEVRLDAKVTSEKETRALGIEVG
                     DFISFDPRTVVTETGFIKSRHLDDKVSAAILLNLLRIYKEEKIELPVTTHFAFSVFEE
                     VGHGANSNIPAQVVEYLAVDMGAMGDDQQTDEYTVSICVKDASGPYHYDFRQHLVALA
                     KEQDIPFKLDIYPFYGSDASAAMSAGAEVKHALLGAGIESSHSYERTHIDSVIATERM
                     VDAYLKSTLVD"
     gene            complement(4264..5589)
                     /gene="brnQ"
                     /locus_tag="VU534_000380"
     CDS             complement(4264..5589)
                     /gene="brnQ"
                     /locus_tag="VU534_000380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006152071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HEU1513020.1"
                     /translation="MAKKGTLTGLLLFGIFFGAGNLIFPPSLGALSGEHFLPAIAGFV
                     FSGVGIAVLTLIIGTLNPKGYIYEISTKIAPWFATLYLSVLYLSIGPFFATPRTATTA
                     YEVGISPLLSDANKGLGLIVFTVLYFAAAYLISLNPSKILDRIGRILTPVFAILIVIL
                     VVLGAIKYGGTSPQAASAAYQASAFGTGFLEGYNTLDALASVAFSVIAVQTLKQLGFS
                     SKKEYISTIWVVGIVVALAFSALYIGLGFLGNHFPVPAEAMKGGTPGVYILSQATQEI
                     FGSTAQLFLAAMVTVTCFTTTVGLIVSTAEFFNERFPQISYKVYATAFTLIGFAIANL
                     GLDAIIKYSIPVLVILYPITIAIVMIVIVNKFVALSKPGMQLTIAVVTVIAIASVLGS
                     SFKVEFLANLVSVLPFAKASLPWLVPAIVGILLSLVLPNKQESDVFEME"
     gene            complement(5760..5852)
                     /locus_tag="VU534_000381"
     CDS             complement(5760..5852)
                     /locus_tag="VU534_000381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEU1513021.1"
                     /translation="MRSARACQFLLEQGYNVINVQGGMLAFEEL"
     gene            complement(5895..6047)
                     /locus_tag="VU534_000382"
     CDS             complement(5895..6047)
                     /locus_tag="VU534_000382"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEU1513022.1"
                     /translation="MKEIAFDAFYQLYQNDQLSLVDVREVDEFAALHLEGAHNLPLSQ
                     LADSYD"
     gene            complement(6207..6785)
                     /locus_tag="VU534_000383"
     CDS             complement(6207..6785)
                     /locus_tag="VU534_000383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase family protein"
                     /protein_id="HEU1513023.1"
                     /translation="MSQIERIKQAIMADSQNASYTERGIEPLFAAPKTARINIIGQAP
                     GLKTQEAGLYWKDKSGDRLRDWLGVDEDTFYNSGYFAVLPMDFYFPGHGKSGDLPPRT
                     GFAEKWHPQVLQELPDIQLTLLIGQYAQAYYLQEKISGKVTERVKHYKDYLPAYFPLV
                     HPSPRNQIWMAKNPWFEAEVVPDLKKRIKTIL"
     gene            complement(6839..8239)
                     /gene="pepV"
                     /locus_tag="VU534_000384"
     CDS             complement(6839..8239)
                     /gene="pepV"
                     /locus_tag="VU534_000384"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HEU1513024.1"
                     /translation="MTAIDFTAEVEKRKEDLLADLFSLLEINSERDDSKADAQHPFGP
                     GPVKALEKFLEIADRDGYPTKNVDNYAGHFEFGDGEEVLGIFAHMDVVPAGSGWDTDP
                     YTPTIKDGRLYARGASDDKGPTTACYYGLKIIKELGLPTSKKVRFIVGTDEESGWADM
                     DYYFEHVGLAKPDFGFSPDAEFPIINGEKGNITEYLHFAGENTGVARLHSFTGGLREN
                     MVPESATAVVSGDLADLQAKLDAFVAEHKLRGELQEEAGKYKVTIIGKSAHGAMPASG
                     VNGATYLALFLSQFGFAGPAKDYLDIAGKILLNDHEGENLKIAHVDEKMGALSMNAGV
                     FHFDETSADNTIALNIRYPKGTSPEQIKSILENLPVVSVSLSEHGHTPHYVPMEDPLV
                     QTLLNIYEKQTGFKGHEQVIGGGTFGRLLERGVAYGAMFPDSIDTMHQANEFIALDDL
                     FRAAAIYAEAIYELIK"
     gene            complement(8252..8857)
                     /locus_tag="VU534_000385"
     CDS             complement(8252..8857)
                     /locus_tag="VU534_000385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002924506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HEU1513025.1"
                     /translation="MKFLELNKKRHATKHFTDKLVDPKDVRTAIEIATLAPSAHNSQP
                     WKFVVVREKNAELAKLAYGSNFEQVSSAPVTIALFTDTDLAKRARKIARVGGANNFSE
                     EQLQYFMKNLPAEFARYSEQQVSDYLALNAGLVAMNLVLALTDQGIGSNIILGFDKSK
                     VNEVLEIEDRFRPELLITVGYTDEKLEPSYRLPVDEIIEKR"
     gene            9028..9828
                     /locus_tag="VU534_000386"
     CDS             9028..9828
                     /locus_tag="VU534_000386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEU1513026.1"
                     /translation="MKKFSLLLAILPFLVACENQATPKETSAQKTIVLATAGDVPPFD
                     YEDKGNLTGFDIEVLKAVDEKLSDYEIQFQRTAWESIFPGLDSGHYQAAANNLSYTKE
                     RAEKYLYSLPISNNPLVLVSNKKNPLTSLDQIAGKTTQEDTGTSNAQFINNWNQKHTD
                     NPATINFSGEDIGKRILDLANGEFDFLVFDKVSVQKIIKDRGLDLSVVDLPSADSPSN
                     YIIFSSDQKEFKEQFDKALKELYQDGTLEKLSNTYLGGSYLPDQSQLQ"
     gene            complement(10010..10849)
                     /locus_tag="VU534_000387"
     CDS             complement(10010..10849)
                     /locus_tag="VU534_000387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001015777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HEU1513027.1"
                     /translation="MNHKIAILSDVHGNATALEAVIADAKNQGASEYWLLGDIFLPGP
                     GANDLVALLKDLPITASVRGNWDDRVLEALDGQYGLEDPQEVQLLRMTQYLMERMDPA
                     TIVWLRSLPLLEKKEIDGLRFSISHNLPDKNYGGDLLVENDTEKFDQLLDAETDVAVY
                     GHVHKQLLRYGSQGQQIINPGSIGMPYFNWEALKNHRSQYAVIEVEDGELLNIQFRKV
                     AYDYEAELELAKSKGKGLPFIEMYEELRRDDNYQGHNLELLASLIEKHGYVEDVKNFF
                     DFL"
     gene            complement(10839..12683)
                     /gene="uvrC"
                     /locus_tag="VU534_000388"
     CDS             complement(10839..12683)
                     /gene="uvrC"
                     /locus_tag="VU534_000388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HEU1513028.1"
                     /translation="MNNLIKSKLELLPTSPGCYIHKDKNGTIIYVGKAKNLRNRVRSY
                     FRGSHDTKTEALVSEIVDFEFIVTESNIEALLLEINLIKENKPKYNIMLKDDKSYPFI
                     KITNERYPRLIITRQVKKDGGLYFGPYPDVGAANEIKRLLDRIFPFRKCTNPPSKVCF
                     YYHIGQCMAHTICKKDEAYFKSMAQEVSDFLKGQDDKIIDDLKSKMAVAAQSMEFERA
                     AEYRDLIQAIGTLRTKQRVMAKDLQNRDVFGYYVDKGWMCVQVFFVRQGKLIERDVNL
                     FPYFNDPDEDFLTYVGQFYQEKSHLVPNEVLIPQDIDEEAVKALVDSKILKPQRGEKK
                     QLVNLAIKNARVSLEQKFNLLEKSVEKTQGAIENLGRLLQIPTPVRIESFDNSNIMGT
                     SPVSAMVVFVNGKPSKKDYRKYKIKTVVGPDDYASMREVIRRRYGRVQREALTPPDLI
                     VIDGGQGQVNIAKQVIQEELGLDIPIAGLQKNDKHQTHELLFGDPLEVVDLSRNSQEF
                     FLLQRIQDEVHRFAITFHRQLRSKNSFSSQLDGIDGLGPKRKQNLMKHFKSLTKIKEA
                     SVDEIVEVGVPRVVAEAVQRKLNPQGEALPQVAEERVDYQTEGNHNEP"
     gene            complement(12723..13424)
                     /locus_tag="VU534_000389"
     CDS             complement(12723..13424)
                     /locus_tag="VU534_000389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001267193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="matrixin family metalloprotease"
                     /protein_id="HEU1513029.1"
                     /translation="MRWLFRLIGAFFSFVWRLFWRLVWIVVLLCVLAFGLLWYLNGDF
                     QGALKQAERSVKIGQQSIDQWEKTGQLPKLSQTDSHQHSEGRWAQASARIYLDPQMDS
                     RFQEAYLEAIQNWNQTGAFNFELVTESSKADITATEMNDGGTPVAGEAESQTNLLTGQ
                     FLSVTVRLNHYYLSNPYYGYSYERLVHTAEHELGHAIGLDHTDEKSVMQPAGSFYGIQ
                     EEDVANLRKIYETSE"
     gene            complement(13503..14735)
                     /gene="murN"
                     /locus_tag="VU534_000390"
     CDS             complement(13503..14735)
                     /gene="murN"
                     /locus_tag="VU534_000390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001229509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation alanyltransferase
                     MurN"
                     /protein_id="HEU1513030.1"
                     /translation="MALTTLTKEEFQTYSDQVSSRSFMQSVQMGDLLEKRGARIVYLA
                     LKQEGEIQVAALVYSLPMLGGLHMELNSGPIYTQQDALPVFYAELKEYAKQNGVLELL
                     VKPYETYQTFDSQGNPIDAEKKSIIQDLTDLGYQFDGLTTGYPGGEPDWLYYKDLTEL
                     TEKSLLKSFSKKGKPLVKKAETFGIRLKKLKREELSIFKNITKETSERREYSDKSLEY
                     YEHFYDTFGEQAEFLIASLNFSDYMSKLQGEQSKLEENLDKLRLDLSKNPHSEKKQNQ
                     LREYSSQFETFEVRKAEARDLIEKYGEEDIVLAGSLFVYMPQETTYLFSGSYTEFNKF
                     YAPALLQKYVMLESIKRGIPKYNFLGIQGIFDGSDGVLRFKQNFNGYIVRKAGTFRYH
                     PSPLKYKAIQLLKKIVGR"
     gene            complement(14740..15960)
                     /gene="murM"
                     /locus_tag="VU534_000391"
     CDS             complement(14740..15960)
                     /gene="murM"
                     /locus_tag="VU534_000391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation alanyltransferase
                     MurM"
                     /protein_id="HEU1513031.1"
                     /translation="MYRYQIGIPTLEYDQFVKEHELANVLQSSAWEEVKSNWQHEKFG
                     VYREEKLLATASILIRTLPLGYKMFYIPRGPILDYGDKELLNFAIQSIKSYARSKRAV
                     FVTFDPSICLSQSLINQEKTEFPENLAIIDSLQQMGVRWSGKTEEMGDTIQPRIQAKI
                     YKENFEEDKLSKSTKQAIRTARNKGLEIQYGGLELLDSFSELMKKTEKRKEIHLRNEA
                     YYKKLLDNFKDKAYITLATLDVSKRSQELEEQLAKNRALEETFTESTRTSKVEAQKKE
                     KERLLEELTFLQEYIDVGQARVPLAATLSLEFGTTSVNIYAGMDDDFKRYNAPILTWY
                     ETARYAFERGMIWQNLGGVENSLNGGLYHFKEKFNPTIEEYLGEFTMPTHPLYPLLRL
                     ALDFRKTLRKKHRK"
     gene            complement(16072..16851)
                     /locus_tag="VU534_000392"
     CDS             complement(16072..16851)
                     /locus_tag="VU534_000392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HEU1513032.1"
                     /translation="MAVMKIEYYSQVLDMEWGVNVLYPDANRVEEPECEDIPVLYLLH
                     GMSGNHNSWLKRTNVERLLRGTNLIVVMPNTSNGWYTDTQYGFDYYTALAEELPQVLK
                     RFFPNMTSKREKTFIAGLSMGGYGCFKLALTTNRFSHAASFSGALSFQNFSPESQNLG
                     SPAYWRGVFGEIRDWTTSPYSLESLAKKSDKKTKLWAWCGEQDFLYEANNLAVKNLKK
                     LGFDVTYSHSAGTHEWYYWEKQLEVFLTTLPIDFKLEERLT"
     gene            complement(16920..18581)
                     /locus_tag="VU534_000393"
     CDS             complement(16920..18581)
                     /locus_tag="VU534_000393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HEU1513033.1"
                     /translation="MSNISLTTLGGVRENGKNMYIAEIGESIFVLNVGLKYPENEQLG
                     VDVVIPNMDYLFENSDRIAGVFLTHGHADAIGALPYLLAEAKVPVFGSELTIELAKLF
                     VKGNDAVKKFNDFHVIDENTEIDFGGTVVSFFPTTYSVPESLGIVLKTSEGSIVYTGD
                     FKFDQTASESYATDFARLAEIGRDGVLALLSDSANADSNIQVASESEVRDEITQTIAD
                     WEGRIIVAAVSSNLSRIQQIFDAADKTGRRIVLTGFDIENIVRTAIRLKKLSLANEIL
                     LIKPKDMSRFEDHELIILETGRMGEPINGLRKMSIGRHRYVEIKDGDLVYIATAPSIA
                     KEAFVARVENMIYQAGGVVKLITQSLHVSGHGNVRDLQLMINLLQPKYLFPVQGEYRE
                     LDAHAKAAMAVGMLPERIFIPKKGTTMAYENGDFVPAGSVSAGDILIDGNAIGDVGNV
                     VLRDRKVLSEDGIFIVAITVNRREKKIVARARVHTRGFVYLKKSRDILRESSELINQT
                     VEEYLQGDDFDWADLKGKVRDNLTKYLFDQTKRRPAILPVVMEAK"
     gene            complement(18756..20978)
                     /gene="recJ"
                     /locus_tag="VU534_000394"
     CDS             complement(18756..20978)
                     /gene="recJ"
                     /locus_tag="VU534_000394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001832038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HEU1513034.1"
                     /translation="MITPTYEWQFALQVEDADFTKIAKKAGLGPEVARLLFERGIQNQ
                     ESLKKFLEPSLEDLHDAYLLHDMDKAVERIRQAIEEGENILVYGDYDADGMTSASIVK
                     ESLEQLGAECRVYLPNRFTDGYGPNASVYKYFIEQEGISLIVTVDNGVAGHEAIALAQ
                     SMGVDVIVTDHHSMPETLPDAYAIVHPEHPDADYPFKYLAGCGVAFKLACALLEEVQV
                     ELLDLVAIGTIADMVSLTDENRILVQYGLEMLGHTQRIGLQEMLDMAGIAANEVTEET
                     VGFQIAPRLNALGRLDDPNPAIDLLTGFDDEEAHEIALMIHQKNEERKEIVQSIYEEA
                     KTMVDPEKKVQVLAKEGWNPGVLGIVAGRLLEELGQTVIVLNIEDGRAKGSARSVEAV
                     DIFEALDPHRDLFIAFGGHAGAAGMTLEVEQLSDLSQVLEDYVREKGADAGGKNKLNL
                     DEELDLEALSLETVKSFERLAPFGMDNQKPIFYIKNFQVESARTMGAGNAHLKLKISK
                     GEASFEVVAFGQGRWATEFSQTKNLELAVKLSVNQWNGQTALQLMMVDARVEGVQLFN
                     IRGKNAVLPEGVPVLDFPGELPNLAASEAVVVKNIPEDITQLKTIFQEQHFSAVYFKN
                     DIDKAYYLTGYGTRDQFAKLYKTIYQFPEFDIRYKLKDLAAYLNIQQILLVKMIQVFE
                     ELGFVTIKDGVMTVNKEAPKREIGESQIYQNLKQTVKDQEMMALGTVQEIYDFLMEKE
                     "
     gene            21255..22013
                     /locus_tag="VU534_000395"
     CDS             21255..22013
                     /locus_tag="VU534_000395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEU1513035.1"
                     /translation="MALVEFKNVEKYYGDYHAFRNINLRFEKGQVVVLLGPSGSGKST
                     LIRTINGLETVDKGSLLVNGHQVAGASQKDLVPLRKEVGMVFQHFNLYPHKAVLENVT
                     LAPIEVLGIDKKEAEKTAQKYLEFVNMWDKKDSYPAMLSGGQKQRIAIARGLAMHPEL
                     LLFDEPTSALDPETIGDVLAVMQKLAHDGMNMIIVTHEMGFAREVADRIIFMADGEVL
                     VDTTDVDNFFDNPSEPRAQQFLSKIINHESDKVK"
     gene            22053..22817
                     /locus_tag="VU534_000396"
     CDS             22053..22817
                     /locus_tag="VU534_000396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000624332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEU1513036.1"
                     /translation="MISLFGLAAAKPVQADTSIADIQKRGELVVGVKQDVPNFGYKDP
                     KTGTYSGIETDLAKMVADELKVKIRYVPVTAQTRGPLLDNEQVDMDIATFTITDERKK
                     LYNFTSPYYTDASGFLVNKSAKIKKIEDLNGKTIGVAQGSITQRLITELGKKKGLKFK
                     FVELGSYPELITSLHAHRIDTFSVDRSILSGYTSKRTALLDDSFKPSDYGIVTKKSNT
                     ELNDYLDNLVTKWSKDGSLQKLYDRYKLKPSSHTAD"
     gene            22830..23507
                     /locus_tag="VU534_000397"
     CDS             22830..23507
                     /locus_tag="VU534_000397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEU1513037.1"
                     /translation="MTDLSSWTAYFQDFGQFFNGFLFTLALAVGSFILAMVLGIFFGA
                     MSTSKRPILRILARIFVEFYQNTPLLVQFVIVFYGLPLISDHIIMIPIYWTAVLCVGL
                     YHGAYIAEVIRSGIQSIPSGQMEAALSQGFTYISAMRLIILPQAFRIILPPLTNQIVN
                     LIKNTSTVAIISGVDLMFVTKSWSALNGNYIPAFLGAALLYFALCFPVAQFGRKMEQA
                     NKKAYSL"
     gene            23517..24176
                     /locus_tag="VU534_000398"
     CDS             23517..24176
                     /locus_tag="VU534_000398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEU1513038.1"
                     /translation="MESILEVLTPDNLVFIFKGFGLTLYISLIAIILSTIIGTVLAVT
                     RNGKNPVLRIISSIYIEFVRNVPNLLWIFTIFLVFKMKSTPAGITAFTLFTSAALAEI
                     IRGGLNAVDKGQYEAGMSQGFTSAQILYYIILPQAIRKMLPAIISQFVTVIKDTSLLY
                     SVIALQELFGASQILMGRYFEPEQVFSLYILIALIYFSFNLAISSLSHMLAKRWQQAA
                     E"
     gene            24434..25624
                     /locus_tag="VU534_000399"
     CDS             24434..25624
                     /locus_tag="VU534_000399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferric reductase-like transmembrane
                     domain-containing protein"
                     /protein_id="HEU1513039.1"
                     /translation="MKSVKGLLFIIASFILTLLTWMNTSPQFMIPGLALTSLSLTFIL
                     ATRLPLLESWFHSLEKVYTVHKFTAFLSIILLIFHNFSMGGLWGSRLAAQFGNLAIYI
                     FASIILVAYLGKYIQYEAWRWIHRLVYLAYILGLFHIYMIMGNRLLTFNLLSFLVGSY
                     ALLGLLAGFYIIFLYQKISFPYLGKITHLKRLNHDTREIQIHLSRPFNYQSGQFAFLK
                     IFQEGFESAPHPFSISGGHGQTLYFTVKTSGDHTKNIYDNLQAGSKVTLDRAYGHMII
                     EEGRENQVWIAGGIGITPFISYIREHPILDKQVHFYYSFRGDENAVYLDLLRNYAQKN
                     PNFELHLIDSTKDGYLNFEQKEVPEHATVYMCGPISMMKALAKQIKKQNPKTELIYEG
                     FKFK"
     gene            complement(25945..26826)
                     /locus_tag="VU534_000400"
     CDS             complement(25945..26826)
                     /locus_tag="VU534_000400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphate aldolase"
                     /protein_id="HEU1513040.1"
                     /translation="MAIVSAEKFVQAARDNGYAVGGFNTNNLEWTQAILRAAEAKKAP
                     VLIQTSMGAAKYMGGYKVARNLIANLVESMGITVPVAIHLDHGHYEDALECIEVGYTS
                     IMFDGSHLPVEENLKLAKEVVEKAHAKGISVEAEVGTIGGEEDGIIGKGELAPIEDAK
                     AMVETGIDFLAAGIGNIHGPYPVNWEGLDLDHLQKLTEALPGFPIVLHGGSGIPDEQI
                     QAAIKLGVAKVNVNTECQIAFANATRKFARDYEANEAEYDKKKLFDPRKFLADGVKAI
                     QASVEERIDVFGSEGKA"
     gene            complement(26967..28295)
                     /gene="vncS"
                     /locus_tag="VU534_000401"
     CDS             complement(26967..28295)
                     /gene="vncS"
                     /locus_tag="VU534_000401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase VncS"
                     /protein_id="HEU1513041.1"
                     /translation="MKRTGLFAKIFIYTFSIFSVLVICLHLAIYFLFPSTYLSHRQET
                     IGQKATAIAQSLEGKDRQSIEQVLDLYSQTSDIKGTVKGEMTEDKLEVKDSLPLDTDR
                     QTTSLFIEEREVKTQDGGTMILQFLASMDLQKEAEQISLQFLPYTLLASFLISLLVAY
                     IYARTIVAPILEIKRVTRRMMDLDSQVRLRVDSKDEIGNLKEQINSLYQHLLTVIADL
                     HEKNEAILQLEKMKVEFLRGASHELKTPLASLKILIENMRENIGRYKDRDQYLGVALG
                     IVDELNHHVLQILSLSSVQELRDDRETIDLLQMTQNLVKDYALLAKERELQIDNSLTH
                     QQAYLNPSVMKLILSNLISNAIKHSVPGGLVRIGEREGELFIENSCSSEEQEKLAQSF
                     SDNASRKVKGSGMGLFVVKSLLEHEKLAYRFEMEENSLTFFIDFPKVVQD"
     gene            complement(28292..28948)
                     /gene="vncR"
                     /locus_tag="VU534_000402"
     CDS             complement(28292..28948)
                     /gene="vncR"
                     /locus_tag="VU534_000402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor VncR"
                     /protein_id="HEU1513042.1"
                     /translation="MKILIVEDEEMIREGVSDYLTDCGYETIEAADGQEALEQFSSYE
                     VALVLLDIQMPKLNGLEVLAEIRKTSQVPVLMLTAFQDEEYKMSAFASLADGYLEKPF
                     SLSLLKVRVDAIFKRYYDTGRIFSYKDTKVDFESYSASLAGQEVPINAKELEILDYLV
                     KNEGRALTRSQIIDAVWKATDEVPFDRVIDVYIKELRKKLDLDCILTVRNVGYKLERK
                     "
     gene            complement(28997..29080)
                     /gene="pep27"
                     /locus_tag="VU534_000403"
     CDS             complement(28997..29080)
                     /gene="pep27"
                     /locus_tag="VU534_000403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_198524447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative autolysis signal peptide Pep27"
                     /protein_id="HEU1513043.1"
                     /translation="MRKEFHNVLSSGQLLADKRPARDYNRK"
     gene            complement(29260..30639)
                     /gene="vex3"
                     /locus_tag="VU534_000404"
     CDS             complement(29260..30639)
                     /gene="vex3"
                     /locus_tag="VU534_000404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit Vex3"
                     /protein_id="HEU1513044.1"
                     /translation="MLHNAFAYVTRKFFKSIVIFLIILLMASLSLVGLSIKGATAKAS
                     QETFKNITNSFSMQINRRVNQGTPRGAGNIKGEDIKKITENKAIESYVKRINAIGDLT
                     GYDLIETPETKKNLTADRAKRFGSSLMITGVNDSSKEDKFVSGSYKLVEGEHLTNDDK
                     DKILLHKDLAAKHGWKVGDKVKLDSNIYDADNEKGAKETVEVTIKGLFDGHNKSAVTY
                     SQELYENTAITDIHTAAKLYGYTEDTAIYGDATFFVTADKNLDDVMKELNGISGINWK
                     SYTLVKSSSNYPALEQSISGMYKMANLLFWGSLSFSVLLLALLLSLWINARRKEVGIL
                     LSIGLKQASILGQFITESILIAIPALVSAYFLANYTARAIGNTVLANVTSGVAKQASK
                     AAQASNLGGGAEVDGFSKTLSSLDISIQTSDFIIIFVLALVLVVLVMALASSNLLRKQ
                     PKELLLDGE"
     gene            complement(30691..31338)
                     /gene="vex2"
                     /locus_tag="VU534_000405"
     CDS             complement(30691..31338)
                     /gene="vex2"
                     /locus_tag="VU534_000405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding subunit Vex2"
                     /protein_id="HEU1513045.1"
                     /translation="MTLLQLQDVTYRYKNTAEAVLYQINYNFEPGKFYSIIGESGAGK
                     STLLSLLAGLDSPVEGSILFQGEDIRKKGYSYHRMHHISLVFQNYNLIDYLSPLENIR
                     LVNKKASKNTLLELGLDESQIKRNVLQLSGGQQQRVAIARSLVSEAPVILADEPTGNL
                     DPKTAGDIVELLKSLAQKTGKCVIVVTHSKEVAQASDITLELKDKKLTETRNTSK"
     gene            complement(31351..32628)
                     /locus_tag="VU534_000406"
     CDS             complement(31351..32628)
                     /locus_tag="VU534_000406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001068247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU1513046.1"
                     /translation="MNPIQRSWAYVSRKRLRSFILFLILLVLLAGISACLTLMKSNKT
                     VESNLYKSLNTSFSIKKIENGQTFKLSDLASVSKIKGLENVSPELETVAKLKDKEAVT
                     GEQSVERDDLSAADNNLVSLTALEDSSKDVTFTSSAFNLKEGRHLQKGDSKKILIHEE
                     LAKKNGLSLHDKIGLDAGQSESGKGQTVEFEIIGIFSGKKQEKFTGLSSDFSENQVFT
                     DYESSQTLLGNSEAQVSAARFYVENPKEMDGLMKQVENLALENQGYQVEKENKAFEQI
                     KDSVATFQTFLTIFLYGMLIAGAGALILVLSLWLRERVYEVGILLALGKGKSSIFLQF
                     CLEVVLVSLGALLPAFVAGNAITTYLLQTLLASGDQASLQDTLAKASSLSTSILSFAE
                     SYVFLVLLSCLSVALCFLFLFRKSPKEILSSIS"
     gene            complement(32985..33155)
                     /locus_tag="VU534_000407"
                     /pseudo
     CDS             complement(32985..33155)
                     /locus_tag="VU534_000407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
     gene            complement(33298..33444)
                     /locus_tag="VU534_000408"
     CDS             complement(33298..33444)
                     /locus_tag="VU534_000408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1513047.1"
                     /translation="MKEANKNHPAGAPTFAKGEGEHANDIVATYSDGTTYYVPLNDVT
                     KYAR"
     gene            complement(33441..33896)
                     /locus_tag="VU534_000409"
     CDS             complement(33441..33896)
                     /locus_tag="VU534_000409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001817843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1513048.1"
                     /translation="MQILCYFTITVVAKPNNSGEVHLDVSIEDNQGGSGYNFSSVSSS
                     SQTAKYEGTVYNNNSSLYITIDKTSDATALLKLKLNNVDNQPATEVPSSGITVKLNAK
                     DNAGNWTSASNKKEVTVKIVSAKPTYPDKILVKNPDNIKDTEKMPLLKN"
     gene            complement(34033..34917)
                     /locus_tag="VU534_000410"
     CDS             complement(34033..34917)
                     /locus_tag="VU534_000410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PucR family transcriptional regulator"
                     /protein_id="HEU1513049.1"
                     /translation="MRAKELQDWFPEARISDQPVEKEGYLTLPLASQQWILLEEAGLS
                     EREKQLVALLTQQEQARSLNPWYSYLVEGKGQAPQVFKKIQLVYCHLSYFQQENLASW
                     LDMMRTLFPNCQTVLQVGAQDYVFVLQQDKYTSVRDILSDTIEAVEYDFGLRLSIMLG
                     QVWSQTGHQALSDLIKAERDLFKTWWRQGHQGVHTFSQLYLWSMGERLVDLKPIKECL
                     HQMILDQDQIQEIILSLWENSAVLTKTAQQLYLHRNSLQYKIDKWEELTGLQLKELTD
                     LTLCYQLILGSLSTIVGL"
     gene            complement(34921..35307)
                     /locus_tag="VU534_000411"
     CDS             complement(34921..35307)
                     /locus_tag="VU534_000411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HEU1513050.1"
                     /translation="MIDVNLINGIALAFEGDAVYSMYIRRHLILKGMTKPNKLHQEAT
                     KYVSAKAQARLIALMLEEQVLTEKEEEIYKRGRNTNSHTKAKNADVVTYRMSTGFEAV
                     MGYLHMTENLERLESLVSWCIQKVEG"
     gene            complement(35300..36643)
                     /locus_tag="VU534_000412"
     CDS             complement(35300..36643)
                     /locus_tag="VU534_000412"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002916477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HEU1513051.1"
                     /translation="MIKIYDTMSRDLREFVPIEDGKIKMYVCGPTVYNYIHVGNARST
                     VAFDTIRRYFEYRGYKVAYISNFTDVDDKIINRAREEGITPQEVADKYIAAFREDVTA
                     LGVKPATRHPRVVEFMADIIRFVEDLIEKGFAYESQGDVYFRVEKSHNYAKLANKTLE
                     DLELGASGRTDEETARKENPVDFALWKSSKPGEISWDSPWGPGRPGWHIECSVMSTEI
                     LGDTIDIHGGGADLEFPHHTNEIAQSEAKTGKAFANYWMHNGFVNIDNVKMSKSLGNF
                     ITVHDALKTLDGQVLRFFFATQHYRKPINFTEKAVRDAETNLKYLKNTYEQPFTGNVD
                     AQELQNFKDKFVAAMDEDFNAANGITVVFEMAKWINSGNYDASVKQALADMLEIFGIV
                     FVEEVLDAEIEDLIQKRQEARANRDFATADQIRDQLVTQGIKLLDTKDGVRWTRD"
     gene            complement(36725..37609)
                     /locus_tag="VU534_000413"
     CDS             complement(36725..37609)
                     /locus_tag="VU534_000413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU1513052.1"
                     /translation="MIQARNKLSQEELSEAKKVINCCQNYDGTYRDPYLSNMLNFDPN
                     MPAFFLYYEKGELVGLLTVYADDQDVEVTILVHPGHRRQGIARALFTSFERETASFPI
                     RSVTFQTERIFLENHPDFASNWGLIEDEETETWLGKDRRPYPLANVSHLEVLLADSSY
                     QDQISQLKFQAFSEEHESREVVDRYVAEALKDPESRLYILLKAGQVIGTCTVDLSTNT
                     NYLYGLAILEPERGKGYGSYLAKSLVNQLIEQNDKEFQIAVEDSNVGAKRLYEKIGFV
                     KQTQVVYLNEKGARDSEV"
     gene            complement(37621..38238)
                     /gene="cysE"
                     /locus_tag="VU534_000414"
     CDS             complement(37621..38238)
                     /gene="cysE"
                     /locus_tag="VU534_000414"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000539958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HEU1513053.1"
                     /translation="MGWWRETIDIVKENDPAARTTLEVLLTYPGVKALAAHRLSHFLW
                     KHGFKLLARMYSQFWRFWTQIEIHPGAQIDSGVFIDHGSGLVIGETAIVEKGVLLYHG
                     VTLGGTGKDCGKRHPTVRKGALISAHAQVIGPVEIGENAKVGAAAVVVADVPSDVTVV
                     GIPAKIVRLHGKKDEPVIHEVEEKREYYVNKLEQAKDASHRSSGL"
     gene            complement(38254..40467)
                     /gene="pnp"
                     /locus_tag="VU534_000415"
     CDS             complement(38254..40467)
                     /gene="pnp"
                     /locus_tag="VU534_000415"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001854499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HEU1513054.1"
                     /translation="MAKQVFQTTFAGRELIVETGQVAKQANGSVVVRYGESTVLTAAV
                     MSKKMATGDFFPLQVNYEEKMYAAGKFPGGFMKREGRPSTDATLTARLIDRPIRPMFA
                     EGFRNEVQVINTVLSYDENASAPMAAMFGSSLALSISDIPFDGPIAGVQVGYVDGQII
                     INPSQEQAEQSLLELTVAGTKHAINMVESGAKELSEEIMLEALLKGHEAVKELIAFQE
                     EIVAAVGKEKAEVELLHVDAELQAEIIAAYNSDLQKAVQVEEKLAREAATQVVKDQVT
                     AVYEEKYADHEEFDRIMRDVAEILEQMEHAEVRRLITEDKVRPDGRKVDEIRPLDAVV
                     DFLPRVHGSGLFTRGQTQALSVLTLAPMGETQIIDGLDPEYKKRFMHHYNFPQYSVGE
                     TGRYGAPGRREIGHGALGERALAQVLPSLEEFPYAIRLVAEVLESNGSSSQASICAGT
                     LALMAGGVPIKAPVAGIAMGLISDGNNYTVLTDIQGLEDHFGDMDFKVAGTRDGITAL
                     QMDIKIQGITAEILTEALAQAKKARFEILDVIEATIPEVRPELAPTAPKIDTIKIDVD
                     KIKIVIGKGGETIDKIIAETGVKIDIDEEGNVSIYSSDQDAINRAKEIIAGLVREAKV
                     DEVYRAKVVRIEKFGAFVNLFDKTDALVHISEMAWTRTNRVEDLVEIGDEVDVKVIKI
                     DEKGRIDASMKALLPRPPKPEHDEKGEKSERPHRPRHQKDYKPKKEFTETSKDSE"
     gene            complement(41152..42018)
                     /gene="metF"
                     /locus_tag="VU534_000416"
     CDS             complement(41152..42018)
                     /gene="metF"
                     /locus_tag="VU534_000416"
                     /EC_number="1.5.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000089969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate reductase [NAD(P)H]"
                     /protein_id="HEU1513055.1"
                     /translation="MSRQTPSLSFEVFPPNPAVGNDNIISALQDMQELAPHFISVTAS
                     NNKFNIKETTVRLADFIQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALR
                     GDIIPDVEPQKDFRYATDLIEFIKEQTPHFDIIGACYPEGHPDSPNQISDIQNLKKKV
                     DAGCSSLVTQLFFDNERFYDFQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIH
                     LPRKFKAILDKYEHDPESLRAAGLAYAVDQIVDLVTQDVAGVHLYTMNNADTAKYIHQ
                     ATHALFNHQSLG"
     gene            complement(42082..44331)
                     /gene="metE"
                     /locus_tag="VU534_000417"
     CDS             complement(42082..44331)
                     /gene="metE"
                     /locus_tag="VU534_000417"
                     /EC_number="2.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-methyltetrahydropteroyltriglutamate--
                     homocysteine S-methyltransferase"
                     /protein_id="HEU1513056.1"
                     /translation="MSTTIIGFPRLGEFRELKFTTEKYFRKEISEEELLAAAKDLRAK
                     HWNIVKEKGITEIPSNDFSHYDNFLDAAFLFNVVPASVQNLDLSDLERYFALGRGYQG
                     EKGDVRALPMKKWFNTNYHYIVPKFEKDTQVKLAGHKIFDEFQEAKELGLNTRPVLVG
                     PFTFLQLSDFEEGVKADDFVDSLVAAYQEVFAKLAELGATRIQLDEAALVKDLTAEEK
                     ALFLNLYNKLLADKKGLEVLLQTYFGDIRDVYADLVNLPVDAIGLDFVEGKKTLELVK
                     GGFPADKTLYVGIVNGKNIWRNNYEKSLAVLEQIPAENIVLTSSCSLLHVPFTTANEE
                     FEPALLNHFAFAVEKLDEIRDLDAIRNGQGSEALAANKELFATERVGENAELRARIAG
                     LTDADYTRLPAFAEREAIQEEAFKLPALPTTTIGSFPQTKEVRAKRLAYRKGELSQKE
                     YDAFLAETIDEWIKWQEDIDFDVLVHGEFERNDMVEYFGQNLSGYLFSKNGWVQSYGM
                     RGVKPPIIWGDVTRLNPITVKWSSYAQSRTNKPVKGMLTGPVTILNWSFPREDISIKD
                     STLQIALAIKDEVLDLEAAGVKIIQIDEAALREKLPLRRSDWYEDYLDWAIPAFRLVH
                     STVAPDTQIHTHMCYSEFTDIIPAIDNMDADVISFEANRSNLEILDELKAKNFQTEVG
                     PGVYDIHSPRVPNEGEIDNTIEAILAKVPSKKVWINPDCGLKTRGIPETKESLIRLVE
                     AAKAAREKL"
     gene            complement(44592..44858)
                     /locus_tag="VU534_000418"
     CDS             complement(44592..44858)
                     /locus_tag="VU534_000418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU1513057.1"
                     /translation="MEGCPSELFSKEEILESDMRVAIMSELIEARYEQGISQKKLEEV
                     SGISQPVIARMETGKTSPQLDTVLKVLASLGKTLAIVPLEQGKS"
     gene            complement(44984..45399)
                     /locus_tag="VU534_000419"
                     /pseudo
     CDS             complement(44984..45399)
                     /locus_tag="VU534_000419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            45555..46556
                     /locus_tag="VU534_000420"
     CDS             45555..46556
                     /locus_tag="VU534_000420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000597989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HEU1513058.1"
                     /translation="MIKTFLSALSVILFSIPIITYSFFPSSNLNIWLSTQPILAQIYA
                     FPLATATMAAILSFLFFFLSFYKKNKQIRFYSGILLLLSLILLLFGTDKTLSSASNKT
                     KTLKLVTWNVANQIEAQHIERIFSHFDADMAIFPELATNIRGEQENQRIKLLFHQVGL
                     SMANYDIFTSPPTNSGIAPVTVIVKKSYGFYTEAKTFHTTRFGTIVLHSRKQNIPDII
                     ALHTAPPLPGLMEIWKQDLNIIHNQLASKYPKAIIAGDFNATMRHGALAKISSHRDAL
                     NALPPFERGTWNSQSPKLFNATIDHILLPKNHYYVKDLDIVSFQNSDHRCIFTEITF"
     gene            complement(46624..49029)
                     /locus_tag="VU534_000421"
     CDS             complement(46624..49029)
                     /locus_tag="VU534_000421"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HEU1513059.1"
                     /translation="MLVSYKWLKELVDIDVPSQELAEKMSTTGIEVEGVESPAAGLSK
                     IVVGEVLSCEDVPETHLHVCQINVGEEEERQIVCGAPNVRAGIKVMVALPGARIADNY
                     KIKKGKIRGLESLGMICSLGELGISDSVVPKEFADGIQILPEDAVPGEEVFSYLDLDD
                     EIIELSITPNRADALSMCGVAHEVAAIYDKAVNFKKFTLTETNEAAADALSVSIETDK
                     APYYAARILDNVTIAPSPQWLQNLLMNEGIRPINNVVDVTNYILLYFGQPMHAFDLDT
                     FEGTDIRVREARDGEKLVTLDGEERDLAETDLVITVADKPVALAGVMGGQATEISEKS
                     SRVILEAAVFNGKSIRKTSGRLNLRSESSSRFEKGINVATVNEALDAAASMIAELAGA
                     TVRKGIVSAGELDTSDVEVSSTLADVNRVLGTELSYADVEDVFRRLGFGLSGNADSFT
                     VSVPRRRWDITIEADLFEEIARIYGYDRLPTSLPKDDGTAGELTVIQKLRRQVRTIAE
                     GAGLTEIITYALTTPEKAVEFTAQPSNLTELMWPMTVDRSVLRQNMISGILDTVAYNV
                     ARKNKNLALYEIGKVFEQTGNPKEELPNEINSFAFALTGLVAEKDFQTAAVPVDFFYA
                     KGILEALFTRLGLQVTYTATSEIVSLHPGRTAVISLGDQVLGFLGQVHPVTAKAYDIP
                     ETYVAELNLSAIEGALQPAVPFVEITKFPAVSRDVALLLKAEVTHQEVVDAIQAAGVK
                     RLTDIKLFDVFSGEKLGLGMKSMAYSLTFQNPEDSLTDEEVARYMEKIQASLEEKVNA
                     EVR"
     gene            complement(49106..49615)
                     /locus_tag="VU534_000422"
     CDS             complement(49106..49615)
                     /locus_tag="VU534_000422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU1513060.1"
                     /translation="MIRKVEMADVEVLAKIAKQTFRETFAYDNTEEQLQEYFEEAYSL
                     KTLSTELGNPDSETYFIMHEEEIAGFLKVNWGSAQTERELEDAFEIQRLYVLQKFQGF
                     GLGKQLFEFALELATKNSFSWAWLGVWEHNTKAQAFYNRYGFEKFSQHHFMVGQKVDT
                     DWLLRKKLR"
     gene            complement(49615..50661)
                     /gene="pheS"
                     /locus_tag="VU534_000423"
     CDS             complement(49615..50661)
                     /gene="pheS"
                     /locus_tag="VU534_000423"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HEU1513061.1"
                     /translation="MSTIEEQLKALREETLASLKQITAGNEKEMQDLRVSVLGKKGSL
                     TEILKGMKDVSAEMRPIIGKHVNEARDVLTAAFEETAKLLEEKKVAAQLASESIDVTL
                     PGRPVATGHRHVLTQTSEEIEDIFIGMGYQVVDGFEVEQDYYNFERMNLPKDHPARDM
                     QDTFYITEEILLRTHTSPVQARAMDAHDFSKGPLKMISPGRVFRRDTDDATHSHQFHQ
                     IEGLVVGKNISMADLQGTLQLIVQKMFGEERQIRLRPSYFPFTEPSVEVDVSCFKCGG
                     EGCNVCKKTGWIEIMGAGMVHPRVLEMSGIDATVYSGFAFGLGQERVAMLRYGINDIR
                     GFYQGDVRFSEQFK"
     gene            complement(51143..52558)
                     /locus_tag="VU534_000424"
     CDS             complement(51143..52558)
                     /locus_tag="VU534_000424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HEU1513062.1"
                     /translation="MTIFPDDFLWGGAVAANQVEGAYNEDGKGLSVQDVLPKGGLGEA
                     TENPTEDNLKLIGIDFYHKYKEDISLFSEMGFNVFRTSIAWSRIFPKGDEEEPNEAGL
                     KYYDELFDELHAHGIEPLVTLSHYETPLYLARKYHGWVDRRMIHFYEKFARTVLERYK
                     DKVKYWLTFNEVNSVLELPFTSGGIDIPKENLSKQELYQAIHHELVASSLVTKIAREI
                     NSEFKVGCMVLAMPAYPMTPNPKDVWATHEYENLNYLFSDVHVRGYYPNYAKRYFKEN
                     DINIEFAAEDAELLKNYTVDFLSFSYYMSVTQSALPTQYNSGEGNIIGGLVNPYLESS
                     EWGWQIDPIGLRIILNRYYDRYQIPLFIVENGLGAKDQLIKDELNNLTVQDDYRIQYM
                     KEHLLQVAEALQDGVEIMGYTSWGCIDCVSMSTAQLSKRYGLIYVDRNDDGSGTLNRY
                     KKMSFTWYKEVIESNGESLFK"
     gene            complement(52571..54409)
                     /locus_tag="VU534_000425"
     CDS             complement(52571..54409)
                     /locus_tag="VU534_000425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEU1513063.1"
                     /translation="MSYKDTVQKILDVIGGEKNVNRVTHCVTRLRLELKDENLVNDDD
                     VKKIPGVIGIMKKNGQYQIILGNDVANYYKEFVKLGNFESDSVVQGHKGNILERIIEY
                     IAGSMTPIIPAMLGGGMLKVLVIILPMLGILQSDSQTIAFLTFFGDAPYYFLPLLLAY
                     SASQKLKVTSTLAMSVAGVLLHPNFVQMVQSGNPLSLFGAPVTPASYGSSVVPILIMV
                     WLMKYIEKIIAKLTLAITKSFLQPTLVLLVSSCIALVVVGPIGVIVGEGLSNLVGQMY
                     GVAGWLTLAILGAIMPFIVMTGMHWAFAPIFLAASIATPDVLILPAMLGSNLAQGAAS
                     MAVALKSKNNNTKQIAFAAGFSALLAGITEPALYGVTLKYKKPLYAAMIGGGLAGLFA
                     GLTSVKAYLFAVPSLIALPQFIYSDVPSNIVNALIVAVISVVITFVLAYIFGIDEEES
                     SSNLEVEAGVSNKKMIFSPISGEIIPLSDVQDKTFSDKLIGDGVAIIPSEGKVYAPFD
                     GKITNIFPTKHAIGLKSDEGVELLIHIGLDTVELKGQGFISHVEEGDRVFKNQLIFEM
                     DLNLIKTKGYETVTPVIVTNTNDFLDVLVLPNNQTIEHSKELLVIL"
     gene            complement(54427..55266)
                     /locus_tag="VU534_000426"
     CDS             complement(54427..55266)
                     /locus_tag="VU534_000426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HEU1513064.1"
                     /translation="MIIKRILNHNAVIAQSKKDIDILLFGRGIAFGRKTGDKVNPIDI
                     EKSFFLKNRDNMTRFTEMFINVPLELVYITEKIINLGKITLGNNFDEIIYINLTDHIS
                     SSIERYKEGIIISNPLRWEISKYYKEEFELGKRALQIIKKELGIELPIDEAAFIALHF
                     VNANLENNFQESYKITEIIMGIEKIIQDFYCTEFNQDSIDYYRFITHIKLFAHRLVEN
                     TTYCDDDDEDLLALMKNKYPREYECGEQVAMFIQTEYNYLLTSSELVYLMAHIRRLTK
                     NLD"
     gene            complement(55566..57260)
                     /locus_tag="VU534_000427"
                     /pseudo
     CDS             complement(55566..57260)
                     /locus_tag="VU534_000427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000268095.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
     gene            complement(57363..58228)
                     /locus_tag="VU534_000428"
                     /pseudo
     CDS             complement(57363..58228)
                     /locus_tag="VU534_000428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000442363.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
     gene            58776..59575
                     /locus_tag="VU534_000429"
                     /pseudo
     CDS             58776..59575
                     /locus_tag="VU534_000429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT        17211 a        13413 c        10845 g        18106 t
ORIGIN      
        1 cactagattt cgaaatcgag taggggataa tctctagccc ctctcacacc accgtacgtg
       61 ccgttcggca tacggcggtt caactaactt ttaacgcatg tcgttcaagg taataatcca
      121 aacacgaaac cagtccacgt ttttcaagga ctggttttga tatagcacgt ttaagtaccg
      181 acttctgagc tactatagta gattgaaact agaatagtac acatctacta tacaacatgc
      241 ccgtcgtaca tcaaaaaaag ttgagacata gcgtcttcaa cttttttaca ttactttaac
      301 tactgattaa agtgagttta cgtcaacttt gataccaaca ccttgagtag ttgtgatagt
      361 caagtttgtt acgtaagttc ctttagctgt agctggtttt gctttttgga ttgtttcgtt
      421 gaaagcttta aagttttcaa ccaatttttc agcttcaaat gatactttac cgatgattgc
      481 ttgaacgtta cctgcacggt cagcacggta agtgatttta ccacctttag actcttcaac
      541 tgctttagca acatccattg ttacagtacc agttttaggg tttggcatca agttacgtgg
      601 tccaaggaca cgtccaagac gtccaacaag agccatcata tcaggtgtag cgataactac
      661 gtcgaagtcc aaccaaccgt cgttgatttt agcaacaagg tcatcttcac caacaaagtc
      721 tgcaccagca gcttttgctt cttcagcttt tgcaccacgt gcgaaaacaa gaacacgtga
      781 agttttacca gtaccgtttg gcaataccat tgctccacgg atttgttggt cagctttttt
      841 aacgtcgatg ttcaagttgt aagcaacttc tacagttgca tcaaattttg caaagttagt
      901 ttcttttgca agtgctacag cttcttctac actgtatgct tttgtgctgt cgattttctc
      961 aagagcagca cgaagttgtt tgcttttttt agccattttc tattctcctt gtaagtggtt
     1021 caatcgattt tcatctccca cgtcacttct cgaaatgatg aagtcttgcg ggttttcagt
     1081 ctactatttt tctcttccta cggccttaag ctcccttgct gtacccaagt acaagcctca
     1141 gtcacttgcc tagtatgaaa agcaactaat agactgctgt gagattttct actgtgttat
     1201 tgattagtca acaacagtga atcccataga acgagcagta ccttcgatca tacgcattgc
     1261 agactctacg tttgctgcgt tcaaatctgg catcttagtt tctgcaattt cttgtacttg
     1321 tgcacgagta actgtagcaa ctttagtttt attaggtgta cctgatcctt tttcaacacc
     1381 tgcagctttt ttcaaaagaa cagcagctgg tggtgttttc gtaacgaaag taaatgattt
     1441 atcttcgtaa actgagataa caactggaat gatcatacca gcttggtcag ctgtacgagc
     1501 gttgaactct tttgtgaatc ccatgatgtt gataccagct tgaccaagag caggtccaac
     1561 cggtggagct ggtgtagctt taccagcagg gatttgcaat tttacaagtt tttcgacttt
     1621 tttagccatt tttaaatcct cctttgtggt tttggcggta attagagatt tttacctccc
     1681 acaagtatgt ttttcacata cccatccatt atacactatt tatctggaat tgcaagagaa
     1741 aagtttattt tttgtactca atgaaaatca aagagcaaac taggaagcta gccgcaggct
     1801 gctcaaagta cagctttgag gttgcagata aaactgacga agtcagctca aaacactgtt
     1861 ttgaggttgt gaatagaacc gacgcagtca gtaggtaagg cgacgctgac gtggtttgaa
     1921 gagattttcg aagagtatta atcgacgtag tctccgcctt caaagccata gtattcttcc
     1981 aaactgagac cacttgcagc aatttcttta gcttcttttc ctacataacg caggtgccat
     2041 tcttcagcca tatagcctgt ttccttttcc ttgcctttga gataacggac aacaaagcca
     2101 taatcagctg catgatccaa gagccattgg gctgcttttt cttctgtcac caaatcacca
     2161 tcagtcccaa tcacatcaaa ggccaagcct gtctggtgtt cgctatagcc aggacgggca
     2221 gagtaacggt cagctgctgc ctttccatct tggttgacat aatcttgata gagcttggtc
     2281 tgagtttcat aacttctaaa accactgtaa tgatcactaa tagggaaacc tgcctcttgc
     2341 atcgctttga tgagtttgac caactctgcc ttggctgttg gattttcccc tggattatag
     2401 tctttagaca atggatagtg tttgttggct acgatgattt catcgtattt cccttgaatg
     2461 ctgtagtaat cacctttatt gaccacttct gctttcttct gggcagctcc ttgagactta
     2521 ctaccgactg ttccatcagc tttggctgtc tgttctgtct tagtttctcc atcttcattt
     2581 tttgtttttt cttgtgaaca agctgctaga ctcaaggcta gcaaagctgt caagactagg
     2641 tatcttttct tcatttctac tcctttattt ctaatagttt atctacttct gacgataaac
     2701 gtttgactaa tcttttaatc tcatccggtt ttgcttggca ggtttctgct gtcatttctt
     2761 caaagggaac ccaccagact ggtccacgac ccttgagacc atgaccattc atatcacctg
     2821 tccgtcgtgg aaacagatgc caatgaagat gagcatcgcc atttcctagc agttcgatat
     2881 tcattttctc agcagcaaag gccttggcaa ctgcctcttg gactaaactc atttcttcta
     2941 gaaaacggag tcttgtctcc tttttcaaat ggtgcaattc gctgacatgc tccttggcta
     3001 gaaagagact atagccttca aaatactggt ggtctccaac cacaagatag cctgtttcca
     3061 actctttgac aaagtaagga ttttcttcct tcttgatgag gtcaattctc tgacaaataa
     3121 ggcacatatt agtccaccaa cgtgctctta agataagcat cgaccattcg ttctgttgcg
     3181 atcaccgagt caatatgggt acgctcatag gaatggctag actctatacc agcaccgaga
     3241 agggcgtgtt tgacttctgc ccctgcagac atagccgctg aagcgtccga accataaaat
     3301 ggatagatat ccagcttaaa tggaatatct tgctctttcg ccaaagccac caaatgttga
     3361 cggaagtcat agtgataagg tccagaagca tccttgacac agatagacac tgtatattcg
     3421 tctgtttgct ggtcatctcc catggctccc atatccacag ccagatattc tactacctga
     3481 gcaggaatgt tagagtttgc accgtgtccc acttcttcaa agactgaaaa agcaaaatga
     3541 gttgttacgg gcaattcaat cttctcttcc ttataaatgc gaaggagatt gagcaaaatc
     3601 gccgcactga ccttgtcatc caaatggcga gacttgataa aacctgtctc tgtcacgaca
     3661 gttcgtgggt caaaactgat aaaatcaccg acctcaatgc caagagcacg agtttctttt
     3721 tcactagtta ctttggcgtc caaacgcact tccatattgt cttgcgtgcg ttctgcagtt
     3781 cctgcatcct tatagacatg gcaagaagtt tggtggatga ggatggttcc tgatactttt
     3841 tcacctgtgc tagccacatg aatggtacag ttttctcctt caatcatgtt ccaaggaaag
     3901 ccaccgatac ggtccatttt gagacggccg tctggtttga cagcacggac aatagcacca
     3961 agcgtatcta catgggcagt cacatagcga tgttgctcat cattttgacc tttaatagtt
     4021 acattgacac cgcccttgga tgtgcgaacc ggctggtaac caaaaccttc tagagtcttg
     4081 actaaatagt ccgcaatctc acgagtaaag cctgttggcg acgcaatggc tgtcagttct
     4141 ttgatatatt ctactgtttg attcatttct tcacctcttt cgctacctat tataacacat
     4201 ttatcatcgg ataaaaaaag aaaatcactc ctgtagactt ggctacaaaa gtgatttaag
     4261 tgattattcc atttcaaaaa catcgctttc ttgcttgttt ggtagaacca atgagagcaa
     4321 gattccaaca atggctggca ccaaccatgg gagagatgcc ttggcaaaag gaagaacgct
     4381 aacaagattt gcaagaaact caaccttaaa cgagcttcct agtacgcttg caatggcaat
     4441 aactgtaacc acagcaattg tcaactgcat acctggtttt gaaagggcaa caaatttgtt
     4501 gacaatgaca atcataacga tagcaatcgt gattgggtac aagataacca gtactggaat
     4561 tgagtacttg ataatcgcat caagacccaa attggcaata gcaaatccaa tcaaggtaaa
     4621 ggctgtcgca taaaccttgt agctgatttg tgggaagcgc tcattaaaga actcagctgt
     4681 tgacacaatc aaaccaacag tcgttgtgaa gcaggttacg gtaaccatag ctgcaaggaa
     4741 gagttgagct gttgagccaa agatttcttg agtggcttgt gacaagatgt aaacacctgg
     4801 tgttccaccc ttcatcgctt cagctggtac tgggaaatga tttccaagaa aacctaaacc
     4861 gatgtaaaga gcgctgaagg caagggcaac aacgatacca acaacccaaa tagttgaaat
     4921 gtattctttc ttacttgaaa atccaagttg tttcaaggtt tgaactgcga ttacgctaaa
     4981 ggccactgag gcaagggcgt ccaaggtatt gtaaccttct aggaaacctg taccaaaggc
     5041 agaagcttga taagcagctg aagcagcttg aggacttgtt ccaccatatt tgatagctcc
     5101 cagaacgacc aagataacaa tcaaaattgc aaagactggc gttaaaatac gtccaatgcg
     5161 gtctaagatt tttgatggat taagcgaaat caaataggct gccgcaaaat acagaaccgt
     5221 aaatacaatc aagccaagtc ctttatttgc atccgacaaa agggggctaa tccctacttc
     5281 gtaagctgtt gtagcagtac gtggggtagc aaagaatgga ccgattgaca agtaaagaac
     5341 tgagaggtaa agagtcgcaa accaaggcgc tatcttcgtt gaaatctcgt agatatatcc
     5401 tttaggattt agcgttccaa taataagggt caagacggcg ataccaacgc ctgaaaagac
     5461 aaaacctgcg atggcaggaa gaaaatgttc tccagataga gcacctagag aaggcggaaa
     5521 aatcaagttc cccgcaccaa aaaatattcc aaacaggagc aaacctgtta gggtaccttt
     5581 tttagccata aaaatctcct tcatatttat aaaatactga cctagtatac cacgattagg
     5641 agtctgaaaa aagcatcacg aggcaaatat taaatgtttt caattttctt aaaaataaga
     5701 attatctaaa aataaaactc tcctacccag tccacaccaa gtaggagaaa tgcaaaattt
     5761 taaagttctt caaaggctaa catgccaccc tggacattga taacattata accttgttct
     5821 aataggaatt ggcaagcacg cgccgatctc attccagatt tgcaaataat ataatgcaag
     5881 cgatctttgt ccaattaatc ataactatca gccaattgac taagcggtag gttgtgggca
     5941 ccttctaaat gaagagctgc aaactcatcc acttctctca catccactaa agaaagctgg
     6001 tcgttttggt aaagctggta aaatgcgtca aaggctattt ctttcattct ttttcttcta
     6061 atactcttcg aaaatctctt caaaccacgt cagcgtcgcc ttaccgtgcg tatgttaccg
     6121 acttcgtcag ttttatctgc aacttcaaag ctgtactttg agcagcctac gactagcttc
     6181 ctagtttgct ctttgatttt cattgactat aaaatggttt taattctttt tttcaaatct
     6241 ggcactactt ctgcctcaaa ccaaggattt ttggccatcc agatttgatt tcgtggtgat
     6301 gggtgaacta gcggaaaata ggctggcaga tagtctttat agtgtttcac cctctccgtt
     6361 accttcccac tgattttctc ctgtaaatag taggcttggg catattgccc aatcaagagg
     6421 gttaactgaa tatcaggcaa ttcctgtaag acctgcggat gccatttttc tgcaaaacct
     6481 gtacgaggcg gaagatcacc cgacttgcca tgtcctggaa agtagaaatc cataggcaaa
     6541 acagcaaaat aacctgaatt gtaaaaggta tcttcatcca cacctagcca gtcccgcaag
     6601 cggtcaccac ttttatcttt ccagtaaagg cctgcttctt gagttttaag tcccggagcc
     6661 tgaccgatga tattgatgcg agcagttttt ggcgctgcaa agagaggctc aatgccacgc
     6721 tctgtatagc tggcattctg cgaatccgcc atgatagcct gtttgattct ttcgatttga
     6781 gacatctact ttccctccaa aaagaagtcc aagcataaga tctcagactt ctatcgtttt
     6841 atttgatcaa ttcgtaaata gcttcggcat aaattgctgc tgctcggaaa agatcatcca
     6901 aggcgataaa ttcattggct tggtgcatgg tatcaatcga gtctgggaac atagcaccgt
     6961 aggcaactcc gcgttctagc aagcgaccaa aggttccacc accgatgact tgttcatgac
     7021 ctttaaagcc agtttgtttt tcatagatat tcaacaaggt ttgcacaagt ggatcttcca
     7081 ttggcacata gtgaggcgtg tgaccgtgtt cagacaggct aacagaaaca actggcaagt
     7141 tttcaaggat tgacttgatt tgttctggac ttgttccttt tggatagcgg atgttgaggg
     7201 caatggtatt atcagcactt gtttcatcga agtggaagac gccggcattc atagaaagag
     7261 cacccatctt ttcatccaca tgagcaatct taagattttc accctcatga tcgttcaaga
     7321 gaattttacc tgcgatgtca aggtagtctt tggctggacc agcaaagcca aactggctga
     7381 ggaagagggc aaggtaagtt gcgccattga cacctgaagc aggcatagca ccgtgggctg
     7441 atttaccaat gatcgtcacc ttgtatttgc cagcttcttc ttggagttct cctctaagtt
     7501 tgtgttctgc aacaaaggca tctagtttag cttgcaagtc agccaagtca cctgaaacga
     7561 ctgctgttgc tgattctggt accatatttt cacgtaaacc acctgtaaag ctgtgaagac
     7621 gggcaacacc tgtattttct cctgcaaagt ggaggtattc cgtgatattt cctttttcac
     7681 cattgatgat tggaaattca gcatctggtg agaaaccgaa atctggtttg gcaagtccta
     7741 cgtgctcaaa gtagtagtcc atgtctgccc agcctgattc ttcgtctgtt ccaacgatga
     7801 agcgaacttt cttagaagtt ggaagaccca attctttgat gattttcaaa ccatagtaac
     7861 aagctgttgt aggaccctta tcgtccgaag ccccgcgcgc ataaaggcga ccatctttga
     7921 tagttggtgt gtaagggtct gtgtcccaac cgctaccagc aggcaccaca tccatatggg
     7981 caaagattcc gagaacttct tctccatcac caaactcaaa atgtcctgca tagttatcaa
     8041 cattcttagt tgggtagcca tcgcggtctg cgatttcaag gaatttctcc aaggctttta
     8101 ctggaccagg cccaaatgga tgctgggcat cagccttgct gtcatcacgt tctgaattga
     8161 tttccaaaag gctaaacaag tcagccaaga ggtcttcttt gcgtttttct acttctgctg
     8221 taaaatcaat tgctgtcatt ttttcttctt tctatctttt ctcgatgatt tcatctactg
     8281 gcaagcggta gcttggttcc aatttttcgt ctgtataacc cactgtgatc aagagttctg
     8341 ggcggaaacg gtcttcgatt tccaaaactt cattaacttt tgatttgtca aaaccaagaa
     8401 taatgttaga accaattcct tggtctgtca atgcaagaac caagttcatg gcaaccaaac
     8461 ctgcattgag agctaggtag tcgctgactt gttgctcact gtaacgggca aactcagctg
     8521 gcagattttt cataaaatat tgaagttgct cttcagaaaa gttattagca ccaccaacac
     8581 gggcaatctt acgagcacgt ttggctaagt ccgtatctgt aaacaaggca atggttacag
     8641 gcgctgatga tacctgttca aaattggaac cataagctaa ctttgccagt tcagcatttt
     8701 tctcacgtac caccacaaat ttccaaggct ggctgttgtg ggcgcttggc gccaaggttg
     8761 caatttcgat agccgtacgc acatctttgg gatcaacaag cttatcagta aaatgcttag
     8821 tcgcatgacg ttttttattt aattcaagaa atttcataat cgatttcctt ttctaattct
     8881 actgcttcca ttctaccata atttgaaaga gcttgcaggg atttttcatg attaagtttt
     8941 tctatcacag acataaaaga tatatattgg tttatcagga aagtttctga taaactagca
     9001 agtactttac atttgaatgg agacagtatg aaaaaattta gcctattact agctatccta
     9061 ccatttttgg ttgcctgtga gaatcaagct acacccaaag agactagcgc tcaaaagaca
     9121 atcgtccttg ctacagctgg cgacgtgcca ccatttgact acgaagacaa gggcaatctg
     9181 acaggctttg atatcgaagt tttaaaggca gtagatgaaa aactcagcga ctacgagatt
     9241 caattccaaa gaaccgcctg ggagagcatc ttcccaggac ttgattctgg tcactatcag
     9301 gctgcggcca ataacttgag ttacacaaaa gagcgtgctg aaaaatacct ttactcgctt
     9361 ccaatttcca acaatcccct cgtccttgtc agcaacaaga aaaatccttt gacttctctt
     9421 gaccagatcg ctggtaaaac aacacaagag gataccggaa cttctaacgc tcaattcatc
     9481 aataactgga atcagaaaca cactgataat cccgctacaa ttaatttttc tggtgaggat
     9541 attggtaaac gaatcctaga ccttgctaac ggagagtttg atttcctagt ttttgacaag
     9601 gtatccgttc aaaagattat caaggaccgt ggtttagacc tctcagtcgt tgatttacct
     9661 tctgcagata gccccagcaa ttatatcatt ttctcaagcg accaaaaaga gtttaaagag
     9721 caatttgata aagcgctcaa agaactctat caagacggaa cccttgaaaa actcagcaat
     9781 acctatctag gtggttctta cctcccagat caatctcagt tacaataaca ctcttcgaaa
     9841 atctcttcaa accacgtcag ctttatctgc aacctcaaag ctgtgctttg agcaacctac
     9901 ggctagcttc ctagtttgct ctttgatttt cattgagtat aagatatact aaaagcgatt
     9961 ggaccagcca atcgcttttt tagtttgcat tggctatttt aggaaactct tacaaaaaat
    10021 caaaaaaatt cttcacatcc tctacatacc catgcttttc tattaagctg gctaataatt
    10081 ccagattgtg cccctgatag ttatcgtcac gacgcagttc ttcatacatt tcgataaagg
    10141 gaagcccctt ccccttggac ttggccaatt ctaactcagc ttcgtaatca taagcaactt
    10201 tacgaaattg gatattgagt aattccccat cttcaacttc tatcacggca tactgggaac
    10261 ggtgattttt taacgcctcc caattaaaat agggcatgcc aatcgaccct ggattgatga
    10321 tttgttgccc ttgacttcca taacgaagca actgcttgtg aacatgacca taaactgcca
    10381 cgtccgtttc cgcatctagc agttggtcaa atttctctgt atcattctca actagcaagt
    10441 caccaccata gtttttgtca ggtaaattat gagagataga aaagcgcaat ccgtcaattt
    10501 ctttcttttc cagcaaaggc aagcttcgta gccagacaat cgttgcagga tccattcgct
    10561 ccatcaaata ctgtgtcata cgcaagagct gaacttcctg tgggtcttct aagccatatt
    10621 gcccatctaa agcctcaagg acacgatcat cccaattgcc tcgaacactt gctgtgatag
    10681 gaaggtcctt tagcagggcg actaagtcat ttgcgcctgg accaggaaga aaaatatctc
    10741 ccagaagcca atattcactg gccccttgat ttttagcatc tgcaatcact gcttctagcg
    10801 ccgtcgcatt gccatgaaca tctgataaaa ttgcgatttt atggttcatt gtggtttcct
    10861 tccgtttggt aatctactct ttcttctgct acttgaggca aggcttctcc ctgcgggttc
    10921 aactttcttt gcacagcctc tgcaacgact ctaggtaccc caacttcgac aatctcatcc
    10981 acactggctt ccttgatttt ggtcaaagac ttgaaatgct tcataagatt ctgcttgcgt
    11041 ttaggtccca gaccgtcaat cccatccaat tgagatgaga aagaattttt ggagcgcagt
    11101 tggcggtgga aagtgatagc aaagcggtgc acctcatctt ggatgcgttg gaggaggaaa
    11161 aattcctgag aattgcgaga caaatccacc acctcaagcg gatctccaaa gagcaattca
    11221 tgggtttggt gcttatcatt cttttgcagc ccagcaattg gaatatccaa gcccagttcc
    11281 tcttggataa cctgcttagc gatattgact tgaccttgcc ccccatcaat cacaatcaaa
    11341 tctggaggag tcaaagcctc acgctgtact cgaccatagc gtctgcgaat gacctctctc
    11401 atgctggcat agtcgtctgg tccaacaacc gtttttatct tgtacttacg gtaatccttc
    11461 ttactcggtt taccgttgac aaagaccacc atagccgaaa cagggctagt tcccatgata
    11521 ttagagttat cgaaggactc gatacgtact ggggtcggga tttggagcaa acgccctaga
    11581 ttttcaatag ctccttgagt cttttcgaca gatttttcta gcagattgaa cttctgctct
    11641 agactaacac gagcattttt tatggctaga ttgaccagtt gttttttctc tccacgttga
    11701 ggcttaagaa tcttggaatc caccaaagcc ttgacagctt cttcgtcaat atcctgcgga
    11761 atcagtacct cattgggaac tagatgagat ttttcttgat agaattgtcc tacataggtc
    11821 aaaaaatcct catctggatc attgaagtag gggaagagat tgacatcgcg ctcgatgagc
    11881 ttaccctgac ggacaaagaa aacctgcaca cacatccagc ccttatccac atagtagcca
    11941 aagacatcgc gattttgcaa atctttcgcc atgacccgtt gcttggttcg aagcgttcca
    12001 atagcctgaa tcaggtcacg gtattccgcc gcacgttcaa actccatact ttgtgctgct
    12061 actgccattt tactcttgag atcatcgatg attttgtcat cctgaccttt cagaaaatca
    12121 gacacctcct gggccataga cttgaaataa gcctcatcct tcttacagat ggtgtgggcc
    12181 atacactggc cgatatggta ataaaaacag accttagagg gcgggttggt acacttacga
    12241 aaagggaata tccgatccag caaccgcttg atttcattgg ctgcccccac atcgggatag
    12301 ggtccaaaat aaagacctcc gtcctttttg acctgacgag tgataatcaa gcgtggatag
    12361 cgctcattgg tgattttgat gaaaggatag gacttgtcat ccttgagcat gatattgtac
    12421 ttgggcttgt tttccttgat caggttgatt tctaggagaa gtgcctcaat attagactcc
    12481 gtaacaataa attcaaaatc cacaatttca gacaccagag cctctgtctt ggtatcatga
    12541 cttccacgaa aataggaccg tactcgatta cgcagatttt tagcctttcc tacatagata
    12601 atggtgccat ttttatcctt atgaatgtag caaccagggc tggtcggcaa gagctctagt
    12661 tttgatttaa tcaagttgtt catagttcca ttatagcaaa aaaagtaggg aaagatagta
    12721 ccctactcac tagtctcata tatttttcgg aggtttgcaa catcctcttc ctggatacca
    12781 taaaaggaac ctgctggttg catgacagac ttctcatctg tatggtccaa gccaatcgca
    12841 tgacctaact catgttctgc cgtatggaca aggcgttcat aggagtagcc atagtatgga
    12901 ttggacaaat aataatgatt caaccgcacc gttacggaca agaattgccc tgttaagaga
    12961 ttagtttgac tttccgcctc tcctgccaca ggagtgcctc cgtcgttcat ctccgtagcc
    13021 gtaatatccg ccttactaga ctcagtcacg agttcaaagt taaaagcacc agtttgattc
    13081 cagttctgga ttgcttctaa ataagcctct tgaaagcgtg aatccatctg cggatccagg
    13141 taaatacgag cagaggcctg tgcccacctt ccttcagaat gctggtgact atctgtctgg
    13201 cttaacttag gcagttgccc tgttttctcc cattggtcaa tactttgttg accaattttt
    13261 actgaccgtt ctgcttgctt tagcgctcct tgaaaatctc cgttcagata ccagagaagt
    13321 ccgaaagcaa gcacacataa gagcacaact atccaaacca gacgccaaaa caaacgccac
    13381 acaaaagaaa agaaagcccc tatcaaacga aaaagccagc gcatgtctct ccacctttct
    13441 agcaaataag aattatttta ctaaaagaag ctaaaagaaa tctaaatact gactttttca
    13501 tcttaacgtc ctactatttt tttgagtaac tggatagctt tgtattttaa aggcgatgga
    13561 tggtaacgga aagtacctgc tttgcgtaca atatagccat taaaattctg tttaaaacgc
    13621 aaaacaccat cacttccatc aaaaatccct tgaatgccta ggaagttgta tttaggtatt
    13681 ccacgtttta tgctttccaa cataacatat ttttgaagca gtgcaggggc atagaactta
    13741 ttaaactcag tgtaggaacc actaaagaga taagtcgttt cctgaggcat ataaacaaat
    13801 aaactcccag ctaaaacaat atcttcttct ccatattttt caatcaagtc tcgcgcttct
    13861 gcttttcgaa cttcaaacgt ttcaaattga ctagaatatt ctctcagttg attttgtttt
    13921 ttctcagaat gaggattttt actcaaatca agtcgcaact tgtccaagtt ttcttctagt
    13981 ttactttgtt caccttgcaa tttgctcata tagtccgaaa aatttaagct tgctatgaga
    14041 aactccgctt gttctccaaa agtatcataa aaatgctcat aatattctaa acttttatca
    14101 ctatattctc tacgttcaga ggtttctttt gttatattct taaaaatcga tagttcttca
    14161 cgttttaact ttttcaaccg aatgccaaag gtttcagcct ttttcaccaa gggtttaccc
    14221 tttttgctaa aacttttaag caaactcttt tcagttaatt cagttaaatc tttatagtat
    14281 aaccaatctg gttctccacc tgggtaacct gttgttaagc catcaaattg ataacctaaa
    14341 tcagtcaaat cttgaataat actttttttc tcagcatcta ttggattacc ttggctatca
    14401 aaagtttgat aagtttcata gggttttaca agcaactcta atacaccatt ttgcttggca
    14461 tattctttta actctgcata aaaaactgga agagcatctt gttgggtata aatcggcccc
    14521 gaattgagtt ccatatgcag accacccagc atgggcaggc tataaaccag agctgcaact
    14581 tgaatttctc cttcttgttt caaagcaaga taaacaattc gagcccctct tttttctagc
    14641 aaatccccca tctggacaga ttgcataaag gaacgagaag aaacctgatc agaataagtc
    14701 tgaaactctt ctttcgtgag tgttgttagt gccatatact tactttctat gtttttttct
    14761 taatgtttta cggaaatcaa gagcaagtct taacagagga tagagaggat gagtgggcat
    14821 tgtaaattca cccaagtatt cttcaatcgt tggattaaat ttttccttaa aatgataaag
    14881 tccaccattg agagagtttt caacaccacc taaattttgc cagatcatac ctcgttcaaa
    14941 ggcatagcga gccgtttcat accaagttaa aattggtgca ttgtaacgtt taaaatcatc
    15001 atccatacca gcatatatat tgacagaggt agtaccaaat tccaaactca aagtagccgc
    15061 taaaggaact ctcgcttgac ctacatctat atattcctgc aagaaggtca attcctctaa
    15121 caaacgttct ttttccttct tctgcgcttc tacttttgaa gttcgagtcg actcagtaaa
    15181 ggtctcttcc aaggctctat ttttcgctaa ctgttcttct aactcttgcg aacgtttaga
    15241 aacatccaag gtggccaagg tgatataggc cttgtcctta aaattatcta acaatttttt
    15301 ataataggct tcattcctca aatgaatctc ttttcgcttc tcagtttttt tcatcaactc
    15361 cgaaaatgaa tctaatagtt ccagtccacc atattgaatc tcaagccctt tgtttcgtgc
    15421 tgttcgaata gcctgttttg ttgacttgga aagtttatct tcttcaaaat tttccttgta
    15481 tattttcgcc tgaatacgag gttgaatggt gtctcccatt tcctccgttt ttcctgacca
    15541 ccttactccc atttgttgca aactatcaat aatagccaga ttttcaggaa attctgtctt
    15601 ttcctgattg attaaacttt gagataggca aatacttggg tcaaaagtca caaaaaccgc
    15661 tctcttactg cgagcatagg acttaataga ctgaatggca aaattcaaga gttctttatc
    15721 cccataatcc aatataggtc ctcttgggat gtaaaacatt ttatagccta gcggaagagt
    15781 tctaatcaaa atactagctg tcgccagtaa tttttcttcc ctgtaaacac caaacttctc
    15841 atgttgccaa ttagacttaa cttcctccca agcactactt tgtaatacat tggctaattc
    15901 atgttctttg acaaactgat catattctaa tgtgggaatg ccaatttgat aacggtacat
    15961 ttcctactct ctttcctcca gtattttatt actattctac tactttcgtt tgaaaagtct
    16021 agtgaaaaca tattttattt tagttctact ccccctatgc tgaagttcaa actaagtcag
    16081 tctctcttct aatttgaaat caattggtag ggttgttaaa aaaacttcca attgtttttc
    16141 ccagtagtac cactcgtgag ttccagcgct atggctatag gtcacatcaa aacctagttt
    16201 tttgagattt ttcactgcga gattattggc ttcgtacaag aaatcctgtt cgccacacca
    16261 cgcccaaagt ttggtctttt tatccgattt tttagccaga ctttcaagag aatagggact
    16321 agttgtccag tctctaatct ctccaaaaac acctctccag taggctggac ttcccagatt
    16381 ttgactttca ggagaaaagt tttgaaagct gagggcacct gaaaaactag ctgcatgaga
    16441 aaaacgattt gtcgtaagag ccagtttgaa gcagccgtag cctcccatag aaagaccagc
    16501 gataaaggtc ttttcacgct tgctcgtcat attagggaag aagcgtttca gaacctgtgg
    16561 caattcctct gctagagccg tgtagtagtc aaaaccatac tgggtatcgg tgtaccaacc
    16621 attgctggta ttgggcataa caacgatgag attagttcct cgaagcaagc gttctacatt
    16681 ggtccgctta agccaactat tatgatttcc agacatcccg tgcaaaaggt acaagacggg
    16741 aatatcttca cactctggtt cttccactcg attggcatca gggtagagga cattcacccc
    16801 ccactccata tccaatactt gtgagtaata ctcgattttc atcactgcca tgattttctc
    16861 cttctatttt tctataagaa aaagccgaaa ctcgactttc tctctgttta tttcaacgat
    16921 tattttgctt ccatgactac tggtaaaatg gctgggcgac gcttggtttg atcaaagagg
    16981 tacttggtca gattgtcacg aaccttacct ttgagatctg cccagtcaaa gtcatctcct
    17041 tgaagatact cttctaccgt ttggttaatc aattctgaac tttcacggag aatatcgcga
    17101 ctcttcttga gataaacaaa tccacgcgtg tgaacacgag ccctagccac aattttcttc
    17161 tcacgacggt tgactgtaat agccacgatg aaaattccat cctctgacaa gaccttacgg
    17221 tcacgaagaa caacatttcc aacatcacca atggcattcc catcaatcaa gatatctcct
    17281 gctgaaaccg atccagctgg aacaaagtct ccattctcgt aagccatggt cgtccccttt
    17341 ttaggaatga agatgcgttc tggcaacatc ccaactgcca tggcagcctt agcgtgagca
    17401 tccaactcac gatactcccc ttggacaggg aagaggtact taggttgcaa aagattgatc
    17461 atcagctgca aatcacgcac atttccgtgc cctgatacat gtaaactttg ggtaatcaat
    17521 ttgacaaccc cacctgcctg ataaatcata ttttccacac gcgcaacaaa ggcttcttta
    17581 gcaatagacg gagccgtagc aatatagact aggtccccat ccttgatttc tacataacga
    17641 tggcgaccaa tcgacatctt acgaagtcca ttgataggct cacccatacg acctgtctca
    17701 agaataatca actcatggtc ttcaaagcga gacatatctt taggcttaat caaaagaatt
    17761 tcgttggcta aagacaactt cttaagacga atcgctgtgc ggacgatatt ttcaatatca
    17821 aatcctgtca agacgatacg tcgacctgtt ttatccgcag cgtcaaaaat ctgctgaata
    17881 cgagaaagat tactggaaac agctgcaacg atgatacgac cttcccagtc agcaatagtt
    17941 tgggtaattt catccctaac ttcactttca ctagccacct gaatattgct gtctgcattg
    18001 gccgaatcac tgaggagagc caggacgccg tcacgaccaa tctctgccaa acgagcaaaa
    18061 tcagttgcat aagattcact agccgtttgg tcaaatttga agtcacctgt ataaacgatg
    18121 cttccttccg atgtcttcaa gacaattccc agactctctg gaacggagta agtcgtaggg
    18181 aagaaggaaa ccactgtccc accaaaatca atctccgtat tctcatcaat gacatggaaa
    18241 tcattaaatt tcttaacggc atcatttcct ttgacaaaga gctttgccaa ctcaatggtc
    18301 aactcagacc caaatacagg aactttagcc tctgccaaga gatacggtag agcaccaatg
    18361 gcatccgcat gcccgtgggt caagaaaacc ccagcaatac ggtcgctatt ttcaaaaagg
    18421 taatccatgt ttggaatcac cacatcgacc cctaattgtt cattttcagg atattttaac
    18481 cctacattca aaacaaaaat ggactctcca atttcagcaa tgtacatatt ttttccattc
    18541 tcacgcacac caccaagtgt tgttaaactg atattactca tttttcctcc aaaatcttag
    18601 tttatcttga ttatagggca attctaccct cttattctaa aagttctgat actttcagcc
    18661 gaatcttttc ctaccattat accatttttt tgatgatttt caaaatgaag gtctgttttc
    18721 aaaaaagagt tgatttccca actctttcct aacttctact ctttttccat caaaaaatca
    18781 taaatttctt gcaccgtacc cagcgccatc atttcttggt ctttaacggt ttgtttgaga
    18841 ttttggtaaa tttgactttc tcctatctcc cgctttggcg cctctttatt gactgtcatc
    18901 acaccatctt ttatcgtcac aaagcctagt tcttcaaata cttgaatcat cttgaccagc
    18961 aagatttgtt gaatattaag atatgcagcc aaatctttca gcttgtagcg aatatcaaac
    19021 tctgggaact ggtaaatagt cttgtacaat ttggcaaact gatctctagt cccataacct
    19081 gtcagataat aagccttgtc aatatcattt ttgaaataga cagcagagaa atgctgttcc
    19141 tgaaaaatgg tcttcagctg agtaatatcc tctggaatgt tttttacgac aacagcttca
    19201 ctagccgcaa gatttggcag ttctccagga aaatccaaga ctggaacacc ttctggcaag
    19261 actgcatttt ttccacgaat gttaaaaagt tgaacacctt ccactcgcgc atccaccatc
    19321 atcaactgga gggcagtttg gccattccat tggttgacag acaatttaac cgctaactct
    19381 agattcttgg tttgagaaaa ctctgtcgcc catctgcctt gaccaaaggc taccacttca
    19441 aaactcgcct cacccttgga aattttcagc tttagatggg cattacctgc ccccatagta
    19501 cgagcacttt cgacctgaaa attcttgata taaaaaatag gtttctgatt atccattcca
    19561 aaaggagcta aacgttcaaa acttttgacc gtttccaagc taagtgcctc caaatccaac
    19621 tcttcatcta ggtttaactt attcttgcca ccagcatctg cacctttttc acgaacataa
    19681 tcttccaaaa cctgagataa atctgagagt tgctcaactt ccagcgtcat acccgctgca
    19741 cctgcatgac ctccaaaggc gatgaagagg tctcgatggg gatccagagc ttcaaaaata
    19801 tcgaccgctt ccacactacg agcactgccc ttggcacgac cgtcttctat attaagaaca
    19861 atgactgtct gtcccaattc ttccaataaa cgaccagcca cgattcctag aaccccagga
    19921 ttccagcctt ccttggccaa gacctgaacc ttcttctcag gatccaccat ggtcttggct
    19981 tcttcataga tagactgaac gatttccttg cgctcttcgt ttttctggtg aatcataagg
    20041 gcaatctcat gcgcttcctc atcatcaaat ccagtcaaca aatcaatggc aggattggga
    20101 tcatccaagc gacccaaggc attcaaacga ggagcaatct ggaaaccaac cgtttcttct
    20161 gttacttcgt tggcagcaat cccagccatg tccagcattt cttgcagacc aatgcgctgg
    20221 gtatgaccca acatttccag accatattga actaagatac gattttcatc cgtcagactc
    20281 accatatctg caatagttcc aatagcgacc aaatcaagca attccacttg cacttcttct
    20341 aacagggcac aagccaactt gaaagcaact ccacaaccag ccaaatattt aaaaggataa
    20401 tccgcatctg gatgttcagg atggacaata gcataagcat ctggcagggt ttcaggcatg
    20461 gaatgatggt ctgtcacaat gacatctact cccatagact gagccaatgc aatagcctca
    20521 tgaccagcaa ccccattgtc caccgtcaca atcaaggaaa tcccttcttg ctcgataaag
    20581 tatttataaa cactagcatt agggccatag ccatcggtaa aacgatttgg caggtaaact
    20641 cggcactcag caccaagttg ttccaaactt tccttcacaa tagaagccga agtcatgcca
    20701 tccgcatcat agtctccata aacaagaata ttttcccctt cttcaatagc ctgacgaatc
    20761 cgctccactg ccttgtccat atcatggagc agataagcat catgtaagtc ctccaaggaa
    20821 ggttctaaaa acttcttcag actttcttgg ttctgaatcc ctctctcaaa caataaccga
    20881 gccacctcag gacccagtcc agccttcttg gctatctttg taaaatccgc atcttctacc
    20941 tgcagggcaa actgccattc ataagtaggt gttatcaaaa agacatccac tctttctaag
    21001 aattctattg cttcattata acatgattta gacgttttct ctatccagat tgctttttta
    21061 taacatttta tagtatattg aaactagaat agtacacctc tacttctaaa atattgttag
    21121 aaatcgattt gactgtcccg atcgattttt cctgttctta tttcactata gtgaattttt
    21181 tcagatatga tttgacaaga acattctttt attgtagaac cgtgttataa aatataacac
    21241 aatagagatc tctcatggct ttagtagaat ttaaaaacgt cgaaaaatat tacggagact
    21301 accacgcatt ccgcaacatc aatctccgtt ttgaaaaagg acaagttgtt gtcctgcttg
    21361 gaccttctgg ctctgggaag tccactctta tccgtacgat caatggttta gagactgttg
    21421 acaaaggaag tctcctagtc aatgggcacc aagttgctgg tgccagccag aaagatttgg
    21481 tacctcttcg caaggaagtc ggcatggttt ttcaacattt taacctttat ccacacaaag
    21541 ctgtgttaga aaacgtaacg cttgcaccca ttgaagttct aggaattgat aaaaaagaag
    21601 ctgaaaaaac cgcccaaaaa tatctggaat ttgtaaatat gtgggacaag aaagattcct
    21661 atcccgccat gctatctggt ggacaaaaac agcggatcgc catcgctcgt ggtcttgcta
    21721 tgcatccgga actcctcctc tttgatgaac caacatctgc tcttgatcct gagactatcg
    21781 gagatgttct agcagttatg cagaaactgg cgcatgatgg gatgaacatg atcatcgtta
    21841 cccacgaaat gggctttgct cgagaggttg cggaccgcat tatctttatg gccgacggag
    21901 aagttttagt agatacgaca gatgtcgata acttttttga caatccaagc gaacctcgtg
    21961 cccaacaatt cctcagcaaa attatcaacc acgaaagtga caaagtcaaa taaggaggcg
    22021 cctatgaaaa aaaattcttt ttatcagcat tattgattag ccttttcggc cttgctgctg
    22081 ccaaaccagt ccaggctgat acaagtatcg cagacattca aaaaagaggc gaactggttg
    22141 tcggtgtcaa acaagacgtt cccaattttg gttacaaaga tcccaagacc ggtacttatt
    22201 ctggtatcga aaccgacttg gccaagatgg tagctgatga actcaaggtc aagattcgct
    22261 atgtgccggt tacagcacaa acccgcggcc cccttctaga caatgaacag gtcgatatgg
    22321 atatcgcgac ctttaccatc acggacgaac gcaaaaaact ctacaacttt accagtccct
    22381 actacacaga cgcttctgga tttttggtca ataaatctgc caaaatcaaa aagattgagg
    22441 acctaaacgg caaaaccatc ggagtcgccc aaggttctat cacccaacgc ctgattactg
    22501 aactgggtaa aaagaaaggt ctgaagttta aattcgtcga acttggttcc tacccagaat
    22561 tgattacttc cctgcacgct catcgtatcg ataccttttc cgttgaccgc tctattctat
    22621 ctggctacac tagtaaacgg acagcactac tagatgatag tttcaagcca tctgactacg
    22681 gtattgttac caagaaatca aatacagagc tcaacgacta tcttgataac ttggttacta
    22741 aatggagcaa ggatggtagt ttgcagaaac tttatgaccg ttacaagctc aaaccatcta
    22801 gccatactgc agattaagga ggacacccca tgacagattt atcatcttgg acagcctatt
    22861 ttcaggattt tggacaattt ttcaatggtt tcctcttcac ccttgcccta gcggttggtt
    22921 cctttatcct cgctatggtt ttgggcatct tctttggtgc catgtcaacc agtaaacgtc
    22981 caattttacg cattttagct cgcatctttg ttgaatttta ccaaaatact cccctcttgg
    23041 tgcagtttgt tattgttttt tatggcctac ctcttatcag tgaccatatc atcatgattc
    23101 caatttattg gacagccgtt ctctgcgtgg gactctatca cggcgcttat atcgctgagg
    23161 ttattcgttc agggattcag tctattccta gtggtcagat ggaggccgcc ttgtcgcaag
    23221 gttttaccta tatcagtgcc atgcgcttga ttatcttgcc tcaggccttc cgcatcattc
    23281 tccctccatt gaccaaccaa attgttaacc tcatcaagaa cacctctact gtagctatca
    23341 tctctggagt agacttgatg tttgtgacta agtcttggtc ggctctcaac ggaaactata
    23401 taccagcctt tttaggtgct gctcttctct actttgctct atgcttccct gttgcccagt
    23461 ttggtcgcaa gatggagcaa gccaacaaaa aagcctattc actttaggag gttactatgg
    23521 aatctatttt agaagtttta accccagata acctagtctt tatctttaaa ggatttggct
    23581 tgaccctcta tatttctctg attgccatca tcctctctac tatcatcggt acggtgctag
    23641 ctgtcacgag aaatggcaaa aatcctgtct tacgcattat ttccagtatt tatatcgagt
    23701 ttgtgcgcaa cgttcccaac cttctctgga tttttactat ctttttggtg ttcaaaatga
    23761 aatccacacc agcaggtatt acagccttta ctctctttac atcagcagcc ttggctgaga
    23821 ttattcgagg cggtctcaat gccgtagaca agggacagta cgaagcagga atgtcacaag
    23881 gcttcacctc agcccaaatc ctctactaca tcattctccc acaagccatc cgcaaaatgc
    23941 taccagccat catttctcag tttgttaccg tgattaagga taccagtctc ctctactctg
    24001 ttatcgccct acaagaactc tttggagcca gccaaattct catgggccgt tatttcgaac
    24061 cagagcaggt cttcagtctt tacatcctga ttgccctcat ctacttcagc tttaacctag
    24121 caatttctag cctgtctcat atgctagcca aacgttggca acaagctgca gaataacact
    24181 cttcgaaaat ctcttcaaac cacgtcagct ctatctgcaa cctcaaaaca gtgttttgag
    24241 caacttgcgg ctagcttcct agtttgctct ttgattttca ttgagtataa acagccactc
    24301 tccagttcaa ttggagagtt ttttgatgag agtagatatt tatagacctc aatttgacac
    24361 catacatttt ctatgataaa atgtaacaaa tttatttaca acaaatcgaa atctaaatga
    24421 aatggaattt tctatgaaat cagtcaaagg actactcttt atcatagcta gttttatctt
    24481 gactcttttg acttggatga acacttctcc ccaattcatg attccaggac tagctttaac
    24541 aagcctatct ctgactttta tcctagccac tcgtctccca ctactagaaa gctggtttca
    24601 cagtttggag aaggtctaca ccgtccacaa attcacagcc tttctctcaa tcatcctact
    24661 aatctttcat aactttagta tgggcggttt gtggggctct cgcttagctg ctcagtttgg
    24721 caatcttgcc atctatatct ttgccagcat catccttgtc gcctatttag gcaaatacat
    24781 ccaatacgaa gcttggcgat ggattcaccg cctggtttac ctagcctata ttttaggact
    24841 ctttcacatc tacatgataa tgggcaatcg tctccttaca tttaatcttc taagttttct
    24901 tgttggtagc tatgcccttt taggcttact agctggtttt tatatcattt ttctatatca
    24961 aaagatttcc ttcccctatc tagggaaaat tacccatctc aaacgcttaa atcacgatac
    25021 tagagaaatt caaatccatc ttagcagacc tttcaactat caatcaggac aatttgcctt
    25081 tctaaagatt ttccaagaag gctttgaaag tgctccgcat cccttttcta tctcaggagg
    25141 tcatggtcaa actctttact ttactgttaa aacttcaggc gaccatacca agaatatcta
    25201 tgataatctt caagccggca gcaaagtaac cctagacaga gcttacggac acatgatcat
    25261 agaagaagga cgagaaaatc aggtttggat tgctggaggt attgggatca cccccttcat
    25321 ctcttacatc cgtgaacatc ctattttaga taaacaggtt cacttctact atagcttccg
    25381 tggagatgaa aatgcagtct acctagattt actccgtaac tatgctcaga aaaatcctaa
    25441 ttttgaactc catctaatcg acagtacgaa agacggctat cttaattttg aacaaaaaga
    25501 agtgcccgaa catgcaaccg tctatatgtg tggtcctatt tctatgatga aggcacttgc
    25561 caaacagatt aagaaacaaa atccaaaaac agagcttatt tacgaaggat tcaagttcaa
    25621 ataagtaatc atactctcct gggatttccc aggagagttt tttatagcca aatgaaataa
    25681 gacaggaacg atggaatttt ggcattcaaa tcaattgata agactatttt atagtggagt
    25741 gaaataggat acgaacaaat tgattaggaa aatcaaatga atttatagaa atcttttagc
    25801 agttatgtta tcctattcta gtttcaaaac gctatagaag cagcattgtg ctagtctaga
    25861 ttcagtttac tatactaaaa cgagtagctt gaaatcaaaa aacccaccct cacaggcagg
    25921 ttttatctgt attattcagc tagattatgc tttaccttct gaaccgaata cgtcgatacg
    25981 ttcttcaacc gatgcttgga tagcttttac accgtcagcc aagaatttac gtgggtcgaa
    26041 gagttttttc ttgtcgtatt ctgcttcgtt tgcttcgtag tcacgagcaa atttacgagt
    26101 tgcgttagcg aatgcgattt ggcattctgt gttaacgtta actttggcaa caccaagttt
    26161 gatagctgct tggatttgct catcaggaat acctgatcca ccgtgcaata cgattgggaa
    26221 tcctggaaga gcttctgtca atttttgcaa gtggtcaagg tcaagacctt cccagtttac
    26281 tgggtaagga ccgtggatgt taccgatacc agctgccaag aagtcgatac cagtttcaac
    26341 cattgcttta gcgtcttcga ttggagccaa ttcaccttta ccgatgattc catcttcttc
    26401 accaccgata gtaccaactt cagcttctac tgagatacct ttagcgtgtg ctttttcaac
    26461 aacttcttta gccaatttaa ggttttcttc aactggaagg tgtgaaccgt caaacatgat
    26521 tgaagtataa ccaacttcga tacactcaag tgcatcttcg tagtgaccgt ggtcaaggtg
    26581 gatagctact ggtacagtga tacccattga ttcaacaagg ttagcgatca agttgcgagc
    26641 aactttgtaa ccacccatgt atttagcagc acccattgaa gtttggatca aaactggagc
    26701 ttttttagct tctgctgcgc gcaagatagc ttgagtccac tcaaggttgt ttgtgttaaa
    26761 tccaccaact gcataaccgt tgtcacgggc tgcttggaca aatttttctg ctgaaacgat
    26821 tgccatttta tcaggcctcc tgtatatttt tatgggtcat cccatttaca ttgttcattt
    26881 tatcactttt tgccaaaaaa atctagtttt tcccgcagtt tcgattgatt ttcttctaac
    26941 tccatctatg taaacccttt ctctccctag tcttggacga cttttggaaa atctataaag
    27001 aaggttaaac tattctcctc catctcgaaa cgataagcta atttttcatg ttctaataga
    27061 ctcttaacca caaagagccc cataccagac cccttgacct tgcgactggc attgtcagaa
    27121 aaagactggg ctagtttttc ttgttcctct gagctacagc tattttcgat aaaaagttct
    27181 ccttctcttt ctccaattcg aactaagcca cctggaacag agtgcttaat ggcattgctg
    27241 atgagattag aaagaatcaa cttcataact gatgggttta gataagcctg ctgatgggtc
    27301 aaactattgt ctatctggag ctctctttcc ttggctagca aggcataatc tttgaccaga
    27361 ttttgcgtca tctggaggag gtcaattgtt tccctatcat ctcgcaattc ctgcacagaa
    27421 gagagggaaa gtatctgcag aacatggtga ttgagttcat ccacaatccc caaggcaact
    27481 cccagatact ggtctctatc cttataacga ccgatattct ctctcatatt ttcgattagg
    27541 attttcaaac tagccagcgg tgttttcaat tcatgagaag ctcctcgtag gaattcgacc
    27601 ttcatcttct ccagctggag aatggcttca ttcttttcat gcaagtccgc aataacagtc
    27661 aagagatgct ggtagaggct attgatttgt tccttgagat tacctatctc atccttagaa
    27721 tccacgcgca atcgcacttg ggaatccagg tccatcatcc gacgggtcac ccgcttgatt
    27781 tccaaaatcg gtgcaacaat agtccgagcg tagatgtagg ccaccaaaag ggaaatcaga
    27841 aaggaggcca gcaaggtata gggaagaaac tggagactga tttgctccgc ttccttttgt
    27901 aaatccatgg aagctagaaa ctggagaatc atagtaccac cgtcttgcgt tttcacctcg
    27961 cgctcctcaa taaagagaga ggttgtctgg cggtctgtgt ccagaggaag actgtccttg
    28021 acttctaact tgtcctcggt catctcacct ttgacggtcc ccttgatatc actagtctgg
    28081 gaatacaagt ctaacacttg ctcgatactc tgcctatctt tcccttctag ggactgggca
    28141 atggctgttg ccttttgacc aatggtttcc tgacgatgac tcagataagt cgaaggaaaa
    28201 agaaaataaa tagctaaatg aaggcagata accagaacac taaatatcga gaaggtatag
    28261 ataaatatct ttgcaaataa acctgttcgt ttcattttcg ctccaattta taaccaacat
    28321 tgcgcacagt gaggatacaa tccaagtcta gctttttccg caattccttg atataaacat
    28381 caataacacg gtcaaaggga acctcatctg tcgctttcca gacggcatcg ataatctgag
    28441 atcgagtcaa ggcccggcct tcatttttca ctagatagtc cagaatttcc aactctttgg
    28501 cattgatagg cacttcttga cctgcgaggc ttgcactgta gctttcaaag tccaccttgg
    28561 tatccttgta agaaaagatt cgtcctgtat cgtagtagcg cttgaaaatc gcgtccaccc
    28621 tcacttttaa aagggagagg gagaaaggtt tttccagata gccatctgcc aaagaggcaa
    28681 aggcactcat cttgtattcc tcatcttgaa aagctgtcaa catcaagaca ggaacctgac
    28741 tggttttacg aatctcagct aggacttcta agccgttgag cttgggcatc tggatatcca
    28801 gtaaaaccag ggccacctca tagctagaaa attgctccag agcttcctga ccgtccgctg
    28861 cctcaatagt ttcatagcca caatccgtca aataatcact gaccccctca cggatcatct
    28921 cttcatcttc tacaattaaa attttcatac tttaactgct ctctattttt tatttttctt
    28981 agaataaata cctaccctat tttctattat agtctcttgc tggccttttg tctgcaagca
    29041 actgaccact agataaaacg ttgtgaaatt cctttctcat aaattccata actttagtat
    29101 attatattta agcactaaag tacaaagaaa gcaactgaaa gcaatgattt tcaccactgc
    29161 tttcggattt attttgaatt gttaaatagc cattcctatc cactattctt gaatagaaac
    29221 acaagatgca atctttattc tagactcatt ttttcaaatt tattcaccat ccagcaagag
    29281 ctcttttggt tgttttctaa ggagattgct tgaagcaagc gccataacga gaaccactag
    29341 aaccaaggca aggacaaaaa tgatgataaa gtctgatgtc tgaatggaaa tgtctaggct
    29401 cgacaaggtc ttgctaaagc catctacttc tgcaccacca ccaaggttag aggcttgagc
    29461 cgccttacta gcctgtttgg caacacctga agtcacattg gcaaggacag tgtttccaat
    29521 tgcacgggca gtgtaattag ctaggaagta agcagaaact agagcaggga tagcaatcaa
    29581 gatagattcg gtgatgaatt gacccaagat acttgcctgc ttgaggccga tagagaggag
    29641 aattcccact tccttgcgac gggcgttgat ccaaaggctg agcaagaggg caaggaggag
    29701 aactgagaag ctcaagctac cccagaagag gaggttggcc atcttgtaca taccagagat
    29761 agattgctca agagctgggt agttagagga gctcttgacg agtgtgtagc tcttccagtt
    29821 gataccactg atgccattca actctttcat aacatcatcc aagttcttgt ctgctgttac
    29881 aaagaaggtt gcgtccccat aaatggctgt gtcttctgtg tatccataaa gttttgcagc
    29941 agtgtgaatg tctgtaatag ctgtgttttc gtaaagttct tgtgagtagg ttactgctga
    30001 cttattatga ccatcaaaga gtcccttgat tgtcacttca actgtttcct tggctccttt
    30061 ttcattatct gcatcgtaga tattagagtc cagtttaacc ttgtccccta ctttccagcc
    30121 gtgtttggct gccaagtcct tgtgcaagag gattttatcc ttgtcgtcgt tggttaagtg
    30181 ctctccttcg actagtttat aagaaccaga gacaaacttg tcttctttag aggagtcatt
    30241 gacacctgta atcatcaagc tacttccaaa acgcttggca cgatcagcag tgagattctt
    30301 cttggtttct ggcgtttcaa tcaggtcata tccagtcaaa tctccgatag cgttgatacg
    30361 tttgacataa gactcaatgg ccttgttttc ggtgattttt ttgatgtctt cacccttgat
    30421 attcccagca ccacgaggcg ttccttggtt gacgcgacga ttgatttgca tggagaagct
    30481 attggtgata tttttaaagg tctcctgaga agccttggca gtagctccct tgattgacaa
    30541 gccgaccaaa ctcaagctcg ccatgaggag aataatcagg aagatgacaa tcgatttgaa
    30601 aaacttcctt gtaacatagg caaatgcgtt gtgtaacata gattcccttt ctagattttg
    30661 ttttaatcat tctattaaaa taagctcaaa ttatttacta gtattgcgcg tttcagtcag
    30721 tttcttatcc tttaattcaa gtgtaatatc tgacgcttgt gccacttctt tactgtgagt
    30781 tacgacaatc acacatttac ctgttttctg ggcaagtgat ttgagtagtt cgacaatatc
    30841 tccagcagtt ttaggatcca gatttcctgt tggctcatca gctagaataa ctggagcttc
    30901 tgagaccaaa ctgcgagcaa tggcaacacg ttgctgttga ccacctgata actggagaac
    30961 attccgcttg atctggcttt catccaaacc aagctcaaga agtgtattct tgcttgcctt
    31021 tttgttgacc aatcggatat tttccagcgg agaaagataa tctatcaagt tataattttg
    31081 aaagaccagg gaaatatggt gcatgcgatg gtaagaatag cccttcttac gaatatcctc
    31141 tccttgaaaa aggatagaac cttcaacagg actatctaga ccagcaagta gggacaagag
    31201 tgtggatttt cctgctcctg actccccaat aatactgtaa aattttccgg gttcaaaatt
    31261 ataattgatc tgatatagga ctgcttcagc agtattctta taacggtagg taacatcttg
    31321 taattgtaat aaagtcatga tttctccttc ttaactaata gatgataaaa tttctttcgg
    31381 tgattttcta aataagaata ggaaacaaag ggctacagat aagcaactaa gcagaactag
    31441 aaaaacatag gattctgcaa aagataagat gctagttgat aaactgcttg ctttggctag
    31501 tgtatcttgt aagcttgcct gatctccact tgctagtaga gtttggagta ggtaagttgt
    31561 gattgcgttt cctgcaacaa atgctggaag caaagctcca agagatacca aaactacctc
    31621 taaacagaat tgtaggaaga tcgagctctt gccttttcca agtgcaagta aaatccccac
    31681 ttcatagacc cgttctctca accagagaga caaaaccaga attaaggctc cagctcctgc
    31741 tatcaacatc ccataaagga agatggtcag gaaggtttgg aaagttgcaa ctgagtcttt
    31801 gatttgttca aaagccttgt tttccttttc gacttggtag ccttgatttt ccaaggccaa
    31861 gttttctacc tgcttcatga gtccgtccat ttccttagga ttttctacat agaagcgtgc
    31921 tgcactgact tgagcttcac tattgcccaa aagggtttgg ctactttcat agtctgtaaa
    31981 gacttgattt tcactgaagt cagaagacaa gcctgtgaat ttctcttgtt ttttaccaga
    32041 aaagatgccg ataatctcaa actctactgt ttgtcctttt ccagattcag actgaccagc
    32101 atccaagcca atcttgtcat gaagcgaaag accgttcttc ttagccaatt cttcgtggat
    32161 aaggattttc ttggaatccc ctttttgaag gtgtcgccct tcttttagat tgaaagccga
    32221 actggtaaag gttacatcct tggatgaatc ctcaagagcc gttaagctaa ccaagttatt
    32281 gtctgcagct gataaatcat cacgctccac gctctgctcg ccagtcactg cttccttgtc
    32341 ttttagtttt gcgaccgtct caagttcagg agagacattt tccagcccct taatcttgct
    32401 tacagatgct aggtctgaca acttgaatgt ctgaccattc tctatcttct taatagaaaa
    32461 agatgtattg agtgatttat aaagattgct ttctactgtt ttgttggact tcatcagagt
    32521 caaacaggct gaaattccgg ccaataagac caataaaatc agaaataaaa taaaacttct
    32581 cagtcgcttt ctgctgacat aagcccaaga tctttggatt ggattcattt gtcacctcca
    32641 tatttgtaag actattataa aacccaaata tgaaatattt atgaaatacg aaaaaaaaat
    32701 atcgagtagg ggataatctc tagcccctct cacaccacca tacgtgccgt tcggcatacg
    32761 gcggttcaac taacttttaa cgcatgtcgt tcaaggtaat aatccaaaca cgaaaccagt
    32821 ccacgttttt caaggactgg ttttgatata gcacgtttaa gtaccgactt ctgagctact
    32881 atagtagatt gaaactagaa tagtacacct ctacttctaa aatattgtta gaaatcgatt
    32941 tgactgtcct gaacaattcg tcctattctt atttcatttt actataattg atagtggtcg
    33001 ccccagccag ataccttatc tgctatccat ttaggaaccc ctaacttaag caatccccat
    33061 aatcgtctcg atttcttctt ccattgcttc cagataatca ctcgtaggcg agtacgcaag
    33121 cgctcatcta tgctagtgac tatacttttc atatttataa ttcattcctt tcgtttcact
    33181 caaggcacaa cacagaatga aaaagtgttg tgatctttat tttgttttat aataatagtg
    33241 agaaaaccta tcactactac aaatcacggg gaggtgaata agtgagtggt acagccacta
    33301 cctcgcatat tttgtcacat catttaacgg tacataataa gttgtaccat ctgaataagt
    33361 tgctacaata tcatttgcat gctctccttc acctttagca aaggttggag ctcctgctgg
    33421 atgattttta tttgcctctt tcaatttttc aataatggca ttttttctgt atcttttata
    33481 ttatcaggat ttttcactaa gattttgtct ggatatgtcg gtttagcaga aacaattttt
    33541 actgttactt cttttttatt cgaagcactt gtccagtttc cagcattatc tttagcattt
    33601 aattttacag taattcctga actaggaact tcagtagcag gttgattatc aacattattc
    33661 aactttaatt tcaaaagagc tgttgcatca gacgttttat caatcgttat atataatgat
    33721 gaattgttat tataaacagt tccttcatat ttagctgttt gtgagctact tgaaacagaa
    33781 ctgaaattat acccactacc tccctgatta tcttcaatgc ttacgtctaa atgaacttcc
    33841 ccactattat ttggcttagc aacaactgtt atagtaaaat aacataaaat ttgcataaat
    33901 agattaggga aatcaaagca gcttctagga atgttttagc agtcacagtg tactttccca
    33961 gcatcaagcc actataactc tgcacataaa aatggagaag atggcaatcc tcttctccaa
    34021 atattaactt ctttacaaac caactatagt tgacaaagaa cctaaaatca attgataaca
    34081 caaggtcagg tcggtcaact ctttcaactg aagccctgtc aactcttccc atttatcaat
    34141 cttgtattgg agagaattgc ggtgcagata gagttgctgg gctgttttag tgagaacagc
    34201 actattttcc caaagagaga gaatgatttc ctgaatctga tcttgatcca aaatcatctg
    34261 gtgtagacat tccttgattg gcttcaagtc cacgagtctt tctcccatac tccaaagata
    34321 gagctgagaa aaagtatgaa caccttggtg accctgacgc caccatgtct tgaacaaatc
    34381 ccgctcagct ttgattaagt ctgatagggc ttgatgtccc gtctgagacc aaacctgacc
    34441 caacatgata gaaagacgaa gtccaaagtc atactcaacc gcttcaatcg tatcacttaa
    34501 aatatctctt acagaagtgt atttgtcttg ttgaagcacg aaaacataat cctgagctcc
    34561 gacctgtagc actgtctgac aattcggaaa aagagtccgc atcatatcta gccaagaagc
    34621 cagattttcc tgctgaaaat aagaaagatg gcaataaacc aactgaatct ttttaaaaac
    34681 ttgcggtgcc tgtcccttgc cctcaaccag ataggaatac caagggttta gcgaacgagc
    34741 ctgctcctgc tgggtcaaaa gggcaaccaa ctgcttttca cgctcgctga gcccagcttc
    34801 ctccagcaaa atccactgct gagaagctaa agggagcgtg agatagccct ctttctctac
    34861 tggttggtct gaaatccgag cctcaggaaa ccagtcttgt agttcttttg ccctcatgtt
    34921 ctagccctcc actttttgga tgcaccatga aaccaaactc tcaagacgtt ccagattctc
    34981 agtcatatgg agatagccca taaccgcttc aaatcccgtg gacatacgat aagtcacgac
    35041 atctgcattt ttagcctttg tgtggctatt ggtattgcgg ccacgtttgt agatttcttc
    35101 ttctttttcc gttaggacct gctcctccaa catgagagca atcaggcgag cctgagcctt
    35161 ggctgacacg tacttagttg cttcttgatg gagtttattg ggtttggtca tacctttgag
    35221 gatgaggtga cggcgaatat acatagaata caccgcatcc ccctcaaagg ctagcgcaat
    35281 cccgttaatg agattgacat caatcacgtg tccacctcac tccatccttg gtatcaagga
    35341 gcttaattcc ttgagtaacc aattggtcac ggatttggtc tgctgtcgca aagtcacgat
    35401 tggcacgcgc ctcttggcgt ttttgaatca agtcttcaat ctctgcatcc aaaacttcct
    35461 caacaaagac aattccaaaa atttctaaca tatctgcaag agcttgcttg acacttgcat
    35521 catagttccc tgagttgatc catttggcca tttcaaagac aactgtgata ccgttggcag
    35581 cattaaaatc ttcatccata gctgctacaa acttatcttt aaagttttgt aactcttggg
    35641 catccacatt tcctgtaaat ggttgttcgt aagtattctt gagatacttg agattggtct
    35701 cggcatcgcg aactgccttt tccgtgaagt tgataggctt acggtagtgc tgggtcgcaa
    35761 agaagaaacg aagtacttgc ccatcaagag ttttaagggc atcgtgtacc gtaatgaagt
    35821 tacccaagga cttagacatt ttgacattgt cgatattgac aaagccattg tgcatccagt
    35881 agttagcaaa agccttgcct gttttagctt cagactgggc aatttcattg gtgtggtgtg
    35941 gaaactctag gtcagctcca ccaccgtgga tatcaatggt atcacctaaa atctctgtcg
    36001 acatgactga acactcaata tgccaacccg gacgtccagg tccccaagga ctatcccaag
    36061 aaatctcacc tggtttggaa gatttccata gagcaaagtc tacaggattt tccttacgag
    36121 ccgtttcttc atcggtacga cctgaagcac ctagctccaa atcttccaag gttttattag
    36181 ccaatttagc atagttgtgg gatttttcta cacggaaata gacatcccct tgactctcat
    36241 aggcaaagcc tttctcgatc aagtcttcca caaaacggat gatgtctgcc ataaactcca
    36301 ctacacgcgg atggcgagtc gcaggtttca cgcccaatgc cgtcacatcc tcacgaaagg
    36361 cagcgatgta cttatccgca acctcctgag gcgtgatacc ttcttccctg gcacggttga
    36421 taatcttatc atccacatct gtaaaattgg aaatataggc aaccttatac ccacggtact
    36481 caaaatagcg acgaatcgta tcaaaagcta ccgtcgaacg ggcgtttcct acgtggatat
    36541 agttgtacac cgttggccca caaacataca tcttgatctt gccgtcctca atcgggacaa
    36601 attctcgcaa atcacgagac atggtgtcat agattttaat cataaatcat aatcaggaaa
    36661 gctgaaatcc aagaacaatt agtttcatca ctaaaagttc aagtaaattt cagtccgaat
    36721 atctctacac ttcggaatcc cttgctcctt tctcattcag ataaaccacc tgagtctgtt
    36781 tgacaaagcc aattttttca tacaaacgtt tggcacctac attgctatct tccactgcaa
    36841 tctgaaattc cttgtcattt tgctcaatta gttggttgac gagggatttt gctaagtagc
    36901 ttccatagcc ttttccacgt tcaggttcca atattgctaa accgtagagg taattcgtat
    36961 tagtcgataa atcaaccgta caagttccaa taacctgacc agcttttaat aaaatatata
    37021 gtcggctttc tggatctttc agagcttcag cgacatatct atccacaact tctctcgatt
    37081 catgttcctc tgaaaatgcc tgaaatttta attgactaat ttgatcctga tacgaactat
    37141 ctgctaacaa aacttcaaga tgggaaacat ttgctaacgg ataaggtctt ctatccttac
    37201 ctaaccaagt ttctgtctct tcatcctcga ttagtcccca gttactggca aagtcaggat
    37261 gattctctaa aaaaatacgt tctgtctgaa aagtgactga ccgaatgggg aaagaagctg
    37321 tttctctctc aaaactagta aacaatgcac gcgcaatccc ctgacggcga tgacctggat
    37381 gaaccagtat cgtcacttct acatcttggt catctgcata gacagttaat aaaccaacaa
    37441 gttcgccttt ttcataataa aggaaaaagg cgggcatgtt tgggtcaaaa ttaagcatgt
    37501 tagagagata gggatcgcga taggtaccgt catagttttg gcaacagtta attacttttt
    37561 tcgcctcaga tagctcctct tggcttaact tgtttcttgc ttgaatcata taggtatcct
    37621 ctacaaacca gacgatctgt gactggcatc tttagcctgc tcgagtttat tgacataata
    37681 ctctcgtttt tcttcgactt cgtgaatgac aggctcatct ttcttaccat gaagacggac
    37741 aatcttggcc ggaataccga caaccgtcac gtcactaggt acatctgcta cgacaactgc
    37801 tgcagcaccg accttggcat tttcaccaat ttccacaggc ccgataactt gggcatgggc
    37861 tgatatgagg gctccctttc gtacagtcgg atggcgtttg ccacagtctt tccctgttcc
    37921 cccgagagtc actccgtgat agagaagaac gcctttttca acaatcgctg tctctccaat
    37981 caccagacca gaaccatggt caataaaaac acctgaatca atctgggctc ctggatgaat
    38041 ctcaatctga gtccaaaagc gccaaaactg actgtacata cgagctaata gtttgaagcc
    38101 gtgcttccag agaaaatgcg agagacggtg ggccgccaag gccttgacac ctggataagt
    38161 cagcaaaacc tccaaagtgg tgcgggccgc tggatcattt tcttttacaa tatcaatggt
    38221 ttcgcgccac caccccatac atttctcctt ttcttattct gaatcttttg atgtttctgt
    38281 aaattctttc ttaggtttgt aatccttttg atgacgtggg cggtgagggc gctcagactt
    38341 ttcacctttt tcatcatgct caggttttgg cggacgaggt agaagagcct tcatagaggc
    38401 atcgatacgg cctttttcat caattttgat aaccttaaca tcaacttcat ccccgatttc
    38461 taccaaatcc tctacacgat tggtacgagt ccaagccatc tcagagatat gaacaagggc
    38521 atctgtctta tcaaagaggt taacaaaggc accaaatttc tcgatacgaa cgactttagc
    38581 acggtaaact tcatccactt tggcttcacg aaccaaacca gcaataattt ctttggcacg
    38641 gttaatagca tcttggtcac tagagtagat agacacattt ccttcttcgt ctatatcaat
    38701 cttaacacct gtttcagcga taatcttgtc gatggtttct ccacccttac cgatgacaat
    38761 cttaatcttg tccacatcaa tcttgatcgt atcaattttc ggagcagttg gagccaattc
    38821 tggacgaact tctggaatgg ttgcttcaat gacatcaagg atttcaaaac gcgctttctt
    38881 ggcttgagca agagcctccg tcaagatttc tgcagtaatc ccttgaatct tgatatccat
    38941 ttgaagggct gtaatcccat cacgagtacc tgcaaccttg aagtccatat ctccaaagtg
    39001 atcttccaaa ccttggatat ctgtcaatac tgtgtagtta tttccatctg agataagccc
    39061 catagcaata ccagctactg gcgccttgat tggcacacca ccagccataa gggcaagagt
    39121 tcccgcacag atagaagctt gagatgaaga accgtttgat tccaaaactt ctgctactag
    39181 acggatagcg taggggaatt cttccaagct tggcaagact tgagcaagag cacgctcacc
    39241 aagggcaccg tgaccgattt cacgacgacc tggcgcaccg taacgacctg tttcccctac
    39301 agaatattga gggaagttat agtggtgcat aaagcgtttc ttgtactctg gatccaaacc
    39361 atcaatgatt tgagtttctc ccatcggagc caaggtcaag actgaaagag cttgagtttg
    39421 cccacgagta aagagacctg aaccatgtac acgaggaagg aagtcaacaa ccgcatccaa
    39481 aggacggatt tcatcgacct tacgaccatc aggacgcacc ttgtcttctg taattaaacg
    39541 tcgcacttct gcgtgttcca tttgttccaa gatttcagcc acatcacgca taatacggtc
    39601 aaattcttcg tggtccgcat atttttcttc gtaaacggca gtcacttggt ctttcactac
    39661 ttgagtcgca gcttcacggg ccaatttctc ttctacttga actgcctttt ggaggtcact
    39721 gttgtaggct gcaatgattt cagcttgcaa ttcagcatcc acgtgaagca attccacttc
    39781 tgctttttct ttaccgacag cagcaacgat ttcttcttgg aaggcaatca attctttgac
    39841 agcttcgtgc cctttaagga gcgcttccaa catgatttct tctgacaatt ctttggcacc
    39901 agactctacc atgttgatag cgtgcttggt tccagctact gtcaattcaa gaagagattg
    39961 ctctgcttgt tcttgacttg ggttgatgat gatttggcca tctacatatc ccacttgtac
    40021 cccagcaatt ggtccgtcaa atggaatatc tgaaatagac agtgccaaag atgaaccaaa
    40081 catagcagcc attggtgcag atgcattttc atcataagaa agcactgtat tgatgacttg
    40141 gacttcatta cggaaacctt ccgcaaacat aggacgaatc ggacggtcaa tcaaacgcgc
    40201 tgtcaaggtc gcatctgttg aaggacgtcc ttcacgtttc ataaagccac caggaaactt
    40261 cccagccgca tacatttttt cttcgtagtt gacttggagt gggaagaaat ccccagttgc
    40321 cattttctta gacataacgg cagcagtcaa gacagttgac tcaccgtaac gtacgacaac
    40381 agatccattt gcttgcttag caacctgacc agtctctaca attaactcac gacccgcaaa
    40441 agtcgtttga aacacttgtt ttgccatttt aatccccttt ggattgatga aattatacgc
    40501 cttgcctaca aagatcaaga taccaaggac gtcaaaagca aagtaaaaat aggaaactga
    40561 cgaagtcttc gatgaagaca agacagttta tcttttttac acagcttttc ggccgtgttc
    40621 aattacacaa gatattttgg acggttcggc ttgccgaaca tttctgtaga aaaataggaa
    40681 ggtgacgtcg cactcgacga gtgctaggaa gcttatcttt tttcctaaga aatgagacca
    40741 aaattcaagt catcaagata ccaagccgtc aagcaactca aaggaagata ggaaatcgaa
    40801 cgacggagcg actactccta gggagattta tctttttcca cagagttgta ggcaagttca
    40861 gttttcaaga tacatcatta gaaaggttta atactaaagt atctaaagct ttcacgctaa
    40921 tcgctatcgg gcgattagct aaatgcttta ctaactctct cgtcaaataa catcgatttg
    40981 actcactcgt gtcgttaaat cttacagttt aaatgcattg tattatttaa taccttcatc
    41041 tttgtatcaa gtacgtacag aatttatttt atcatatttt tcttaaaaag tgaggtcttt
    41101 accattaaaa aggaaccatt cccctcacct gagaagaatg gtttgctttt attatcctag
    41161 agactggtga ttaaacaagg catgggttgc ttgatggatg tattttgctg tatcagcatt
    41221 attcatcgta tagagatgca caccggcaac atcctgagtt accaagtcca cgatttggtc
    41281 cactgcatag gcaagtcctg ctgctctgag cgactcaggg tcatgctcat acttgtctaa
    41341 gatggcttta aatttgcgtg gaagatggat attctcacaa gtcttcaaga gtcggagagc
    41401 ctgatttcga ttcagaattg gcataattcc tgcatgaatg ggaacatcaa tcccagccaa
    41461 gatacacttg tcctgaaaat catagaagcg ctcattgtca aagaagagct gagttacgag
    41521 gctcgaacag cctgcatcca ctttcttctt aagattttga atatctgaaa tctgatttgg
    41581 cgaatctgga tgcccttctg gatagcaagc tccaataata tcaaagtgag gggtttgttc
    41641 cttgataaac tcaatcaagt cggttgcata gcggaaatcc ttttgtggtt ccacgtctgg
    41701 aataatatcc ccacgaagag ccaagatttt ctgcacccca actttgtcca agtcagcaat
    41761 agtttcagca accttgtcct tagttagata aatagctggc aagtgggcaa tggtcggaat
    41821 cgccaaatca ttttggataa agtcagccaa acgaaccgtc gtttccttga tattaaattt
    41881 attattgctg gcagttacac tgataaaatg gggagccaac tcctgcatat cctgcaaggc
    41941 tgaaataatg ttatcattac ccacggctgg gtttggaggg aacacttcaa atgagagtga
    42001 cggtgtttgg cgtgacatat gtaataacct tttctagttg atttcttttt gaacaaccac
    42061 tgtatggaga gaaatccaat cttacaattt ctcacgcgca gctttagctg cttcaacaag
    42121 gcggatcaag ctttcttttg tttctgggat accacgtgtt ttcaaaccac agtcagggtt
    42181 gatccaaact ttcttgcttg gcactttagc aaggatggct tcgattgtgt tgtcgatttc
    42241 gccttcattt ggtacacgag gtgagtggat atcgtaaacc ccaggtccca cttctgtttg
    42301 gaagtttttc gctttgagtt cgtccaagat ttcaaggttt gaacggttag cttcaaagga
    42361 aataacgtct gcatccatgt tatcgatagc tgggatgata tctgtaaatt ctgagtaaca
    42421 catgtgagtg tggatttgtg tgtctggcgc tactgttgag tgtaccaagc ggaaggcagg
    42481 aatagcccag tcaaggtagt cttcgtacca gtcgctacgg cggagtggca atttttcacg
    42541 aagagcagcc tcgtcgattt ggatgatttt cacaccagca gcttcaaggt caagtacttc
    42601 atccttgata gcaagggcga tttggagagt tgaatccttg atagagatgt cttcacgtgg
    42661 gaatgaccag ttaaggatgg taacaggtcc agtcaacata cctttaacag gtttgtttgt
    42721 acgactttgt gcatagctag accatttaac agtgataggg ttaagacgag tgacatcacc
    42781 ccagatgatt ggtggtttta ccccacgcat accgtatgat tgtacccatc catttttaga
    42841 gaagaggtat cctgacaagt tttgaccgaa gtactcaacc atgtcattac gctcaaattc
    42901 accgtgaaca aggacatcaa agtcaatatc ttcttgccac ttgatccatt cgtcaatcgt
    42961 ttcagcaagg aaagcgtcgt actctttttg agacaattca cctttacggt aagccaaacg
    43021 tttggcacga acttcttttg tttgagggaa tgaaccaatc gttgttgttg gaagagctgg
    43081 aagtttgaaa gcttcttctt ggatagcttc acgttctgca aaggctggca aacgagtgta
    43141 gtctgcgtct gtcaagccag cgatacgcgc acgaagttca gcattttcac caacacgctc
    43201 agtcgcaaag agttctttgt tggctgcaag agcttctgaa ccttgaccat ttcggatagc
    43261 atccaagtca cggatttcat ccaatttttc aactgcaaag gcaaagtggt tcaagagtgc
    43321 tggttcaaat tcttcattag cagttgtaaa tggcacatga agaagtgagc aagagcttgt
    43381 caaaacgatg ttttcagctg gaatttgctc aagaacagcc aagctctttt cgtagttgtt
    43441 gcgccagatg tttttaccat tgacaatacc tacatagaga gtcttgtcag ctgggaagcc
    43501 acctttaacg agttcaagag ttttcttacc ttcaacaaag tcaagaccga tagcatctac
    43561 tggtaagttt acaaggtcag cgtatacgtc acgaatatca ccgaaataag tttgaagcaa
    43621 gacttcaaga ccttttttgt cagccaagag tttgttgtaa aggttcaaga agagagcttt
    43681 ttcttcagct gtcaagtctt ttacaagagc cgcttcatcc aattggatgc gagtcgcacc
    43741 aagttcagcc aatttagcaa aaacttcttg gtaagcagcc actaagctat ctacgaagtc
    43801 gtctgctttc acgccttctt caaagtctga caattgaagg aaagtgaagg gacctacaag
    43861 aacaggacga gtgttcaatc caagttcttt ggcttcttgg aactcatcga aaatcttgtg
    43921 accagccaat tttacttgag tgtctttttc aaatttagga acgatgtagt ggtagttagt
    43981 gttgaaccat ttcttcattg gaagggcgcg aacgtcccct ttttctccct ggtaaccacg
    44041 tcccaaagcg aagtagcgct caaggtcaga caagtccaag ttttgaacgg atgcaggcac
    44101 cacgttgaaa aggaaagccg catctaggaa gttatcatag tgagaaaagt catttgatgg
    44161 aatttcagtg atgccttttt ctttgacaat gttccagtgt ttagcacgca agtcttttgc
    44221 tgctgctaaa agttcttctt ctgagatttc ttttctaaag tatttttcag ttgtaaattt
    44281 taattcacgg aattcgccca aacgagggaa accgatgatt gtagttgaca tgatgtgtcc
    44341 tccaaaattt gttgttgaaa ctatcttaac agaaaagaaa gcgtctgtat aattgtaaaa
    44401 aattagggtt tgatatagtt tgaaactata tatctgtttc ggacaaaaga aaaagacttg
    44461 aagcaaacgt ctcaaatcct ttgtaattct tactttacag ctatattcca attagaatac
    44521 taaaacatgt tattagtaat tcttataagt gactatgacc tgttattaga aaagactata
    44581 actgattcta gtcaactttt tccctgttca agtgggacga ttgctagtgt ctttcctaaa
    44641 ctggctagga cttttaagac tgtatccaac tgaggactag tctttcctgt ctccatccta
    44701 gctatgacag gctggcttat tccactgact tcttccagct ttttctgact gattccttgt
    44761 tcatacctag cctcaatcaa ctcgctcatg atagccactc gcatatcact ttcaaggatt
    44821 tcctccttgc taaagagctc agatggacat ccttccaatt actcccaata gcactattct
    44881 tcatcactta accctctttt ttttacgtct atgtattttt aaaaaaatga gcgaattatg
    44941 attcgataga ttgaccagtg ggtttaaagt tggtgctagc ctatttctta agcgattttc
    45001 cttttctagg ataaagcagt tcctgcttgc ttaaccccaa ttttccacga tgaatccaat
    45061 agtaaatggt tgaaattccc acgttaaccc ctttagccat caccatcatt tcaggcgaaa
    45121 atttttggtt atgtttttgg ttatgtatag tggagaatct tttcctttag tttcttaaga
    45181 ctgttgagcg tagtcggcag aataaatctc tttgaagcgc ccttttccaa gacattgtcg
    45241 gactgtccca cgcttgattt cagtgtggat agtttgagga gcttttccaa gtagagaggc
    45301 aatttctcta tttgattttc cttctttttt ccatcgttcg attaagcgac ggctatcgat
    45361 tgtcaaatgt ttgccttttg tagtataatt gtcttgcatt tctgtgcctt ttaatcattt
    45421 caatcttaaa ttggactttt tttacttggg ttgtacttaa tctatgagga agacaagaaa
    45481 aagaatatca atcaagtaaa gtcacaaagt cacattagct ccgagcaacc attgcaaatt
    45541 gaggtactca cacaatgatt aaaacatttc tctctgccct ttcggtcatt ctcttttcta
    45601 tccctatcat aacttattct tttttcccat cttctaatct taacatttgg ctatctaccc
    45661 aacctatctt ggcacagatt tatgccttcc ccttagctac tgcaactatg gctgctattt
    45721 taagtttctt attttttttc ctatcttttt acaagaaaaa taaacaaata cggttttact
    45781 ctggcatttt gctcttacta tcgctcatat tactattatt cggaacagat aaaacccttt
    45841 cttctgcatc aaataagact aaaaccttaa aattagtaac ttggaacgtc gctaatcaaa
    45901 tagaagcaca acatattgag cgaattttta gccattttga cgccgatatg gctatattcc
    45961 ctgaactagc taccaatatc agaggtgagc aagaaaacca gagaatcaaa ctattgtttc
    46021 atcaagttgg actttctatg gccaactatg atattttcac ttctccacct accaatagtg
    46081 gaatagctcc tgtgactgtg attgtcaaga aaagttatgg tttctataca gaagctaaaa
    46141 cttttcatac aacacggttc gggacaattg tattacattc gagaaaacaa aatataccag
    46201 atatcattgc cttgcatact gcgcctcctc tgccaggttt aatggaaatc tggaagcaag
    46261 acttaaacat cattcataat caattggctt caaaatatcc aaaggctatt attgcaggtg
    46321 attttaatgc aactatgcgt catggagcac ttgcaaaaat aagctctcat agggacgcat
    46381 taaatgcact gccacctttt gaaagaggaa cttggaatag ccaaagtcca aaacttttta
    46441 atgcaacaat agatcatatt ttattgccta aaaaccacta ctatgttaaa gatttagaca
    46501 ttgtaagttt tcaaaactct gatcatagat gtatttttac agaaatcaca ttttaattat
    46561 tttatataaa atcacccctc taatgttcat aaactagagg gggaatttgt atcctactat
    46621 cgtttaacgc acttctgcat tgactttttc ttcgagagac gcttggattt tttccatata
    46681 gcgtgcgact tcttcgtccg ttaagctgtc ttctggattt tggaaggtca agctataagc
    46741 cattgacttc ataccaagtc ccagtttttc acctgagaag acgtcaaaga gtttgatatc
    46801 tgtcaaacgt ttcacgccgg cagcttggat agcatctaca acttcttggt gagtcacttc
    46861 tgccttgagg agaagggcaa cgtcacggct gactgctggg aatttggtga tttccacaaa
    46921 tggaacagca ggttggagcg ccccttcgat ggctgaaagg ttaagctcag ctacatacgt
    46981 ttctggaata tcgtaagcct tggcagtgac tggatgcact tggccaagga aaccaagaac
    47041 ttggtcaccg agtgaaatca cggctgtacg acctggatga aggctaacga tttcagatgt
    47101 tgctgtatag gttacttgga gtcccaaacg agtaaatagg gcttcaagga ttcccttagc
    47161 atagaagaaa tcaactggaa ctgctgctgt ttggaaatct ttttcagcaa ccaagcctgt
    47221 caaggcaaag gcaaagctgt tgatctcatt tggaagttct tcttttggat tacctgtttg
    47281 ttcaaagact tttccaatct cataaagggc caagttttta ttcttacgag ccacgttgta
    47341 ggcaacggta tcaaggatcc ctgaaatcat attttgacgg aggactgaac gatccacagt
    47401 cattggccac atgagttcag taaggttact tggttgagct gtgaactcaa ctgctttttc
    47461 aggagttgtc agagcatagg tgatgatttc tgtcaaacct gctccttcag caatggtacg
    47521 aacttgacgg cggagttttt gtatcacagt caattcacca gctgtaccat cgtcttttgg
    47581 aaggctggtt ggcaagcggt catatccata gatacgagcg atttcttcaa agagatcagc
    47641 ttcgattgtg atatcccaac gacgacgtgg tacgctgact gtaaagctgt ctgcatttcc
    47701 agaaagacca aagccaagac gacggaagac gtcttctaca tcagcataag acagctcagt
    47761 tccgaggaca cggttaacat cagcaagggt tgaagaaact tccacatcag aggtatcaag
    47821 ctcacccgct gaaacgatac ccttacgcac cgtcgcgcct gcaagctctg caatcatgct
    47881 agctgccgca tcaagggctt cattaactgt tgccacatta attccttttt caaagcgaga
    47941 agatgactca gaacgaaggt tcaggcgacc acttgtctta cggatagatt tgccattaaa
    48001 aacagcagct tcaaggataa cacgactaga tttttcagaa atttctgtag cctgaccacc
    48061 cataacaccg gcaagggcta ctggtttgtc agcaactgta atcacgaggt ctgtctcagc
    48121 caagtctcgt tcttcaccgt ccagggtcac taatttttca ccatcacgcg cttcacgcac
    48181 acggatgtca gtcccttcaa atgtgtccaa gtcaaaagca tgcataggtt gaccaaagta
    48241 gagcaggatg tagtttgtca cgtctacaac gttattgatg ggacggatgc cttcgttcat
    48301 gagaaggttt tgcaaccatt gtggacttgg tgcgatagtc acattgtcca agatacgagc
    48361 tgcatagtaa ggcgccttgt ctgtctcaat gctgacagaa agggcatctg ccgcagcttc
    48421 attagtttct gttagagtaa attttttaaa gttgactgcc ttgtcataga tggctgccac
    48481 ttcgtgagcc actccacaca tagaaagggc atctgcacgg tttggtgtga tggaaagttc
    48541 gatgatttca tcatccaagt ctaggtaaga aaagacttcc tcacctggca cggcatcttc
    48601 aggcaagatt tggatgccat ctgcgaattc cttaggcaca actgagtcag aaattcccaa
    48661 ttcaccaagt gaacagatca ttccaagtga ctccaaacca cggatttttc cttttttgat
    48721 tttgtagtta tcagcgatac gagctcctgg aagagccacc atgaccttga tcccagcacg
    48781 cacatttggg gcaccacaaa cgatctgacg ctcttcttct tcgccaacgt taatctgaca
    48841 aacatggagg tgagtctctg gcacatcttc gcaagacaag acctcaccga cgacaatttt
    48901 tgagagacca gcagctggtg attcgacacc ctctacctcg atccctgtag ttgacatttt
    48961 ttcagccaac tcttgtgatg gcacatcaat gtccaccaat tcttttaacc atttataaga
    49021 tacaagcata atttagttct ccagaatgac agttgtcact ctagttcttt tcctttccta
    49081 tcatttcaat agaagaatcc tcttcttacc ttaatttctt tctcagtaac caatccgtat
    49141 ctactttttg accaaccata aaatgatgtt ggctaaattt ttcaaaacca tatcggttat
    49201 aaaacgcttg agcttttgta ttatgctccc aaacacctag ccaagcccaa gaaaaactat
    49261 tttttgtagc aagttcaagt gcgaattcaa acagttgctt acctagtcca aatccttgga
    49321 atttttgtag cacatagaga cgttgaattt caaaagcgtc ctctaattct ctctcagttt
    49381 gagcacttcc ccagttgact ttgagaaaac cagctatctc ctcctcatgc ataatgaaat
    49441 aggtttcaga gtcaggattt cccaactcag ttgacaaagt tttcagacta taagcctctt
    49501 caaagtattc ctgtaactgc tcttccgtat tatcatacgc aaaggtttca cgaaaggttt
    49561 gtttggcaat tttagccaac acctcaacat ctgccatttc tacttttcta atcattattt
    49621 aaactgttct gagaagcgga catctccttg gtagaatcca cggatatcgt tgattccata
    49681 acggagcata gctacacgct cttgtccaag accaaaggca aagccagagt atacagtcgc
    49741 atcgatacca ctcatttcaa ggacacgtgg gtgaaccata ccggccccca taatttcgat
    49801 ccaacctgtt ttcttacata cattacagcc ttctccacca cacttgaagc aagaaacatc
    49861 cacctcaaca gatggctctg tgaatgggaa gtaagatgga cgcaaacgaa tttgacgctc
    49921 ttcaccaaac attttttgga caatcaactg aagcgttcct tgaagatcag ccatagagat
    49981 atttttccca actaccaagc cttcgatttg gtggaattgg tgactgtggg tcgcatcgtc
    50041 cgtatcgcga cggaagacac gccctggcga gatcatcttc aaaggacctt tagaaaaatc
    50101 atgggcatcc atagcacgcg cctgaactgg agacgtgtgg gtacggagca agatttcttc
    50161 agtgatatag aaagtatcct gcatatcacg agctgggtgg tcttttggaa ggttcatacg
    50221 ttcaaagtta tagtagtctt gctccacttc aaaaccatcc acgacttgat aacccatacc
    50281 gatgaagata tcttcgattt cttcactggt ttgtgtcaaa acgtgacggt gaccagtcgc
    50341 aactggacga cctggaagcg tcacatctat actctcgcta gccagttgag ccgcgacttt
    50401 cttttcttcc aagagcttag ctgtttcttc aaaagcagca gtcaagacat cacgagcttc
    50461 attgacgtgt ttcccgatga ttggacgcat ctcagcagaa acatctttca tccctttgag
    50521 gatttcagtg agcgaaccct ttttaccaag gacagagaca cgcaaatctt gcatctcttt
    50581 ttcatttcca gcagtaatct gcttcaagct agccagcgtt tcttcgcgaa gcgcttttaa
    50641 ttgttcttca atagttgaca tatttcctcc atcagtctct cgtagataaa aagaaaacca
    50701 catgccaaaa actccactcg gagcgttgac acgcggtacc atccgttttc atctgacaag
    50761 tcagaccttc atttctaaat ccatgcgcaa gtgaattcac ccagctttca tatagagagc
    50821 ttgcagtcac ggctctcctc cctgatatac ttcccttggg ctactagtct ttcagattcc
    50881 tattcaatta ctacttagtt tatcagattt ttaccattct tgcaagacct atcttacttc
    50941 tgcttgttag cttattctta tctaaattta tataaacaat ttatctaaat taactattta
    51001 taatttttgt aacaaaatta aattaattga cactccccta taaaataaag aagtttagaa
    51061 tttaatgtct tccaaacttc tttattccat atttaatgaa atgccacctt aaccgtgata
    51121 atagctagtc atcaataaaa aactatttga ataaggattc tccatttgat tcaatcactt
    51181 ctttatacca agtaaaagac attttcttat atcgatttaa tgtaccactt ccatcatcgt
    51241 ttcgatcaac ataaatgaga ccgtaccttt tagaaagttg tgcagtggac atagaaacac
    51301 agtcaataca tccccaagac gtatagccca taatttcaac accatcctgt agagcttcag
    51361 caacttgcaa taaatgttct ttcatatact gaattctata atcatcttgg acggttaagt
    51421 tattaagttc atcttttatt agttgatctt tagcacctaa tccattttct actataaata
    51481 atgggatttg ataacggtca taatatctat ttaaaattat acgtagtcca attggatcaa
    51541 tttgccatcc ccactctgaa gactctaaat aaggatttac taaaccacca ataatattcc
    51601 cttctcctga attatactgt gttggaagag cagattgagt cacactcatg taatagctaa
    51661 aggataaaaa atctacggta taatttttta ataactctgc atcttcagct gcaaactcta
    51721 tgttaatgtc attttcctta aaatatcttt ttgcataatt cggataataa cctctaacat
    51781 gcacatctga aaatagataa tttagattct catactcatg agtcgcccat acatcttttg
    51841 gatttggagt cattggataa gctggcatag ctaataccat acatcccacc ttaaactctg
    51901 aattaatctc acgagcaatt tttgtaacca aacttgaggc gactaattca tgatgtatag
    51961 cttgatataa ttcttgtttc gaaagattct ccttaggtat atctattcct ccactagtaa
    52021 atggtaattc caaaacagag tttacttcgt taaatgtaag ccaatattta actttatctt
    52081 tatacctttc taaaactgtt cgagcaaatt tttcataaaa atgaatcatt ctcctatcaa
    52141 cccatccatg atattttctt gctaaatata atggagtctc atagtgtgaa agagttacaa
    52201 gtggttctat cccgtgagca tgtagttcat caaacaattc atcataatat ttcaacccag
    52261 cttcgttagg ttcttcctca tctccttttg gaaaaattct actccatgca atagaagtac
    52321 gaaaaacatt aaagcccatt tcagaaaaca aggatatatc ttccttatat ttatgataaa
    52381 aatcaatacc tatcaatttt aagttatctt ctgtaggatt ttctgttgct tctcctaatc
    52441 cacctttggg taacacatcc tgaactgata agcccttacc atcttcatta tatgctccct
    52501 ctacttgatt agctgcaaca gctccacccc aaagaaaatc atctggaaaa atggtcataa
    52561 ctttcctcca ttataatatt accagtaatt ccttagaatg ctcgattgtc tgattattag
    52621 gtaatactaa tacatctaga aaatcattgg tattcgttac aattactggt gtaactgttt
    52681 cgtagccttt agtcttgatt aaattcaagt ccatttcaaa aatcaactga tttttgaaaa
    52741 ctctgtctcc ttcttctaca tgactaataa aaccttgacc ttttagctca acagtatcta
    52801 atccaatatg aattagtaac tcaacaccct catcactctt caatccaatt gcgtgcttag
    52861 tcggaaaaat atttgtaatt ttcccatcaa atggtgcata aaccttacct tcacttggga
    52921 taatcgctac tccgtctcca attagtttat ctgaaaatgt tttatcctgg acatcgctta
    52981 acggaatgat ttctcctgat ataggagaaa atatcatttt tttatttgaa actccagctt
    53041 caacttctaa attgctagaa ctctcttctt catcgattcc aaatatataa gctaatacaa
    53101 aggtaataac aaccgaaatg accgccacaa ttaaagcatt tacaatattt gatggcacat
    53161 cagaataaat aaattgaggc aacgctatca aagatgggac agcaaataga tatgctttaa
    53221 cactagtaag acctgcaaat aatcccgcta atccaccacc aatcatagct gcataaagcg
    53281 gttttttata ttttaaagtc acaccatata atgcaggttc ggtaatccct gcaagtaagg
    53341 ctgagaaacc tgctgcaaaa gcaatttgtt ttgtattatt atttttactc tttaatgcaa
    53401 cagccatcga agcagcccct tgagctaagt ttgaccctaa cattgctgga agaattaata
    53461 cgtctggagt agcaatagat gccgccaaaa aaataggtgc aaaagcccaa tgcattccag
    53521 tcataacaat aaatggcata atagcaccaa gaatagctaa tgtaagccat ccagctacac
    53581 catacatttg cccaactaga tttgataatc cttcaccaac aattactcca ataggtccga
    53641 ctacaactaa ggcaatacag cttgatacta ataatactag cgtaggttgc aaaaaactct
    53701 tagtaatagc tagtgttaat ttagcaatta ttttttcaat atatttcatc aaccaaacca
    53761 taataagaat tggaacgact gatgaaccat aactagctgg tgtcacaggt gcaccaaata
    53821 aactaagagg attccctgat tgcaccattt gaacaaaatt tggatggaga agtacacctg
    53881 ctacagacat agctaatgta gatgttactt ttaatttttg tgatgcagaa taagctaata
    53941 acagcggtaa gaaataatat ggagcatccc caaaaaatgt caaaaaagca atagtctgag
    54001 aatctgattg caatatacca agcattggta aaatgattac caagactttc aacatacctc
    54061 cccctaacat tgctggaatg attggagtca tggaaccagc gatatactca atgattcttt
    54121 ctaaaatatt ccctttgtgc ccttgaacaa ctgaatcgga ttcaaaattg ccaagtttaa
    54181 cgaattcttt ataataatta gctacatcat taccaagtat aatttgatat tgtccattct
    54241 ttttcataat acctattaca cctggtatct tcttcacatc atcatcattg actaaatttt
    54301 catcttttaa ttctaatctt aaacgtgtta cacaatgggt aactctattg acattttttt
    54361 cacctccaat tacatcgagg attttttgta ccgtatcttt ataactcatg gtattctcct
    54421 attctattaa tctaaatttt ttgttaagcg acgaatatga gccatcaaat aaactaattc
    54481 actagaagtc agcaaataat tgtactccgt ttgtataaac attgctacct gttcaccaca
    54541 ttcatattct ctaggatatt tatttttcat taatgctaac aagtcttcat catcatcgtc
    54601 acaataagtt gtattttcaa ccaagcgatg ggcaaataat tttatatgag ttatgaatct
    54661 ataataatca atagaatctt ggttaaactc agtacaatag aaatcttgaa tgattttctc
    54721 aattcccata attatttcag tgattttata cgactcttga aaattatttt ctaaattagc
    54781 attaacaaaa tgtagcgcta tgaatgcagc ttcgtcaatt ggaagttcaa tacctaactc
    54841 tttttttatt atttgtaaag cccttttccc aagttcaaat tcttctttat aatatttcga
    54901 tatttcccag cgtaggggat tcgaaataat aatcccttct ttataacgtt ctatgctcga
    54961 agaaatatga tccgttaaat taatatagat aatttcatca aaattattac ccaatgttat
    55021 tttacctagg ttaattattt tttcggtgat gtacaccaac tccaaaggaa cgttaataaa
    55081 catctctgta aaacgggtca tattatctct atttttgaga aaaaaacttt tctcaatatc
    55141 aattggattt actttatctc cagtttttct tccaaaagct attccccttc caaaaagaag
    55201 aatatcgata tcttttttac tttgcgcaat tacggcattg tggtttagta ttcgttttat
    55261 gatcataaaa tttccctttt aaaataaaag gaacctactt aaaaacatca agaaacttct
    55321 tctgatgtga ttaaataggt tcctgctcac ttgtattagt gataacatcc ttttatttca
    55381 atttttaatg gtgacatgaa gcttaaataa ttaataactc tgtaaccgtt tttattttat
    55441 gatatttcaa tctatttgtc aagtacttat aaaaattttt ttattttgtg tgattcgaat
    55501 gtgataatgg caacagtctc actaaagaaa tgaaaatcat acatagaaat ttttaaaaat
    55561 tttctctatc gtaaacctgc cactagttca gaaactatac tagctgattc caaacgtaat
    55621 atggtcatct catctacctt ccctaataat ggcattgcac cataccaaac aatagtctta
    55681 ttcaccaaaa gaataggcgt tactattttt gattgagtaa aagacacttt aattttctgg
    55741 ctcttcaact ggtctagcca tgctttattt gcaaccgtct ctggtataca tatctcaatt
    55801 tgactaatcc taaattcttt tagaaaattc atcagttttg tctggtgcac ataaggtaaa
    55861 ataagcagac attcctgtct ttcccctgct aagtcctctc tcaacacctt ctcatatcta
    55921 ctatcaacat aaacgaattg tttctcctca ccctcgatga cacgataatc catctttcga
    55981 taagctactt gtcgtttctg aaacatcttt tctaaataag gaacatgaat atccacataa
    56041 tcgaaaatac gcaccaaaga cttatccttg tagtttctat gaatccgacc tgcatactga
    56101 atcaaattat ttttccaaga aaagggtgct gccaagataa gcgtgtccaa ctgaggtaag
    56161 tcaaaacctt cgccaatgta ttttccagta gacaacaaaa caaacccttt atctaactgt
    56221 tctaacgtct ccagtaaact cgttctctct cggactttgg tttttccgct aataatgtaa
    56281 cagtcatcaa cctctttctc tttcaataat ttttcaaaga catctatctg ttgaattcga
    56341 ttaactaaaa ccaagatatt ccgtccttct gccacttggg ctagaatatc cttgagaatc
    56401 atctgattcc tcactgagtc agtagcaatc caatcactaa gctgtataaa attacttgct
    56461 ttggtctttt caatttccaa atgaccaaaa gaagtgaatc ttaattgcaa ttgccgttta
    56521 aaatccgttt ccctcttatc agcagtatgg agtatctcac caattctctg aaaaacaata
    56581 ggctcatgac cattcttacg ctcaggcgta gccgtcaaac cgtaaagata cttccctcta
    56641 aactgagcaa caactttttc aaacatcaag gcagagacat gatgacactc atccacaatc
    56701 atcatctcat actcatccaa aagactttga ctattttcca acttaaatag agattgaatc
    56761 ataacgacat caaccagttt actcagccat ttcttagtcc caccgtactg cccaacatag
    56821 ccgattacct tttcacgacc tgatgccgta taacggatag cctcctcctc ttcgaaagtc
    56881 aaaaagcagt ttaagcgatc tagccattgg tctaagagtt gcttattatg gactagaata
    56941 attgtttttg ttttccgttc agagataaga gcagcaccta aaacggtctt cccaaaacca
    57001 gtctccgcat gaagtaaacc attttcttta gaagtcatat ctgacagggc taactcttgc
    57061 tcaaaagtga gttctccctt aaattccacg ctaatagacc tttgtacctt tctcctatct
    57121 tccacagata cctgcttaaa tttatcttgc aatggataca gcaaacctct tggcaaccat
    57181 aaataatgat cggattctcc aaataaatac attctctcag gaatttgata ggttggctgt
    57241 cgcatagcct gctttaaata tagtaaaatg aaataataac aggacaaatc gatcaggaaa
    57301 gtcaaatcga tttctaacaa tgttttagaa gcagaggtgt actattctag tttcaatcta
    57361 ctataaaatt cgggattaga aaaggaagcc atatttttca agaaaaaagt gccttggatg
    57421 tcacagacga tttttcaagt tggatcatat tggataaaac gaccttcaac tccttatcca
    57481 attcttgctt gcctaactcc tcttggatta acagtgccac tttagcagtt gaaatcctct
    57541 gaatttcttg tagatacctc cattggtctt cataaggctg aaactgttca tccacaaaga
    57601 ccgttcgccc ttgatggtaa gcttctcctt gaaaaggcaa ggcaatcaaa tttccaaatc
    57661 cccccttagg aaggacatcc tgatttggaa acatgcgatc aaaagaatca aaggacagtt
    57721 gcatactttc ctgcattgcc agttctatca gtttctttcc aaacaagcga gcctctcgac
    57781 tcggaatcgc ttcctcaaag aagaaccaaa tatggagtcc gtgacccgaa cgagaaatct
    57841 ctaaatgggc ttccatctgg cgttccctgg ctattcttcg aatggttaaa ccagcttctt
    57901 tccaatctcc ttcatccaaa tccagtacca aaaaataaca gctatcatct aagtgcatag
    57961 gaaagatacc gatagctgcc tccccacgaa aatgagattt caaaacggag ttcgtcaatg
    58021 tctggaaact ccgtttttca ggtggcaact gcttccaacc ataatcatag gaaggaaaat
    58081 actgaatttt cccttgttca ttgataaaat tcttagcata aacatcataa cggccagcaa
    58141 acacagaggt aaacaattgt aatttttctt gcgtcgtcaa gcgactactt tgaagttgga
    58201 acatctcctc gaactgagag cgttccataa caaactgact cttgtcttta agacgtttat
    58261 agtggaatga aataagatat gaacaaattg attaggaaaa tcaaattaat ttatagaaat
    58321 cttttagcag tcatggcgtc ctattccaga ttcaaaatgc tatacacaag aaaaactcac
    58381 tatccccatt aaaagaagaa aagacatcaa ggacttctac cacaattcca tccaaagaca
    58441 caaaaacagc cataagagtc acctccttga ttcctatagg ctgattataa caagactggc
    58501 tgaaattgta catgaaaata aaatcctaat agtactcatt ttgtatgtga ctaatattcc
    58561 gtctcgctcc agaaggtacg aagtaaatag agtttaaacg agcagtctat aaaattcaaa
    58621 aaacgcatat tatcaagcga cctaaaactt tgggctctat aatatttgta gtgggtaaat
    58681 tccctatgga tattatggag cctattttgg gtagaaaaaa agtcccataa gatctataat
    58741 gaaaagcgac aaaacaactc attagaaaga atcatatgga acaattacat tttatcacaa
    58801 aattactaga cattaaagac cctataaaat tccttacctt gaaacgactg gtatgcctac
    58861 tagaattctc cttagaaaac gtcgttttaa gtgctatcat tgcttgaaaa tgatggtcgc
    58921 tgaaacttct atcgtcaaga aaaatcacca aattcctcgt attatcaacc aaaagattgc
    58981 gcaaaagtta attgaaaaga tttctatgac cgatattgcc catcagctgg ccatttcaac
    59041 ttcaactgtc attcgaaagc tcaatgactt ccactttgag tgtaatttta gaaatctgcc
    59101 taagattatg tcttgggacg ttgaaacagt ccggggagtg actgtttcaa tcgggagatg
    59161 gagatgagct ttattgcgca agattttgaa aagctcgata tcatcactgt tcttgagggt
    59221 agaacacaag ctgtcatccg agatcacttt cttaaatatg atagagccgt ccgatgtcgc
    59281 gtcaaaatta ttactatgga tatgtttagt ccttactatg acttagctaa acagcttcgc
    59341 tttcaaattt ctaggctcag gctgaaacag tctcccagac tgtttcactc ccgaatgcta
    59401 aaatcgttct tgatcgcttt catattgtac aacatcttag ccgtgctatg agtcgtgtgc
    59461 gtgtccaaat catgaatcag tttcatcgaa aatcccatga atacaaggct atcaagcgct
    59521 actggaaact cattcaacag gatagccgta aactcagcga taaacatttt tatcg
//
LOCUS       DAVFER010000007        58433 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1105170250
            SAMEA2167659-rid19724873.denovo.007, whole genome shotgun sequence.
ACCESSION   DAVFER010000007 DAVFER010000000
VERSION     DAVFER010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2167659
            Sequence Read Archive: ERR388902
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 58433)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 58433)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928716.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928716.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 04:07:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,118
            CDSs (total)                      :: 2,073
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 120
            CDSs (without protein)            :: 120
            Pseudo Genes (ambiguous residues) :: 0 of 120
            Pseudo Genes (frameshifted)       :: 67 of 120
            Pseudo Genes (incomplete)         :: 47 of 120
            Pseudo Genes (internal stop)      :: 34 of 120
            Pseudo Genes (multiple problems)  :: 23 of 120
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..58433
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2167659-rid19724873.denovo.007"
                     /strain="1105170250"
                     /db_xref="taxon:1313"
     gene            complement(115..1281)
                     /gene="recA"
                     /locus_tag="VU534_000430"
     CDS             complement(115..1281)
                     /gene="recA"
                     /locus_tag="VU534_000430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HEU1513065.1"
                     /translation="MAKKPKKLEEISKKFGAEREKALNDALKLIEKDFGKGSIMRLGE
                     RAEQKVQVMSSGSLALDIALGSGGYPKGRIIEIYGPESSGKTTVALHAVAQAQKEGGI
                     AAFIDAEHALDPAYAAALGVNIDELLLSQPDSGEQGLEIAGKLIDSGAVDLVVVDSVA
                     ALVPRAEIDGDIGDSHVGLQARMMSQAMRKLGASINKTKTIAIFINQLREKVGVMFGN
                     PETTPGGRALKFYASVRLDVRGNTQIKGTGDQKETNVGKETKIKVVKNKVAPPFKEAV
                     VEIMYGEGISKTGELLKIASDLDIIKKAGAWYSYKDEKIGQGSENAKKYLAEHPEIFD
                     EIDKQVRSKFGLIDGEEVSEQDTENKKDEPKKEEAVNEEVPLDLGDELEIEIEE"
     gene            complement(1336..2592)
                     /locus_tag="VU534_000431"
     CDS             complement(1336..2592)
                     /locus_tag="VU534_000431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000642700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HEU1513066.1"
                     /translation="MKAEIIAVGTEILTGQIVNTNAQFLSEKLAEIGVDVYFQTAVGD
                     NEVRLLSLLEIASQRSSLVILTGGLGPTEDDLTKQTLAKFLGKALVFDPQAQEKLDIF
                     FTLRPDYARTPNNERQAQIVEGAIPLPNETGLAVGGKLEVDGVTYVVLPGPPSELKPM
                     VLNQLLPKLMTGSKLYSRVLRFFGIGESQLVTILADLIDNQIDPTLAPYAKTGEVTLR
                     LSTKASSQEEANQALDILENQILDCQTFEGISLRDFCYGYGEETSLASIVVEELKRQG
                     KTIAAAESLTAGLFQATVANFSGVSSIFKGGFVTYSLEEKSRMLDIPAKNLEEHGVVS
                     EFTAQKMAEQARSKTQSDFGISLTGVAGPDSLEGHPVGTVFIGLAQDQGTEVIKVNIG
                     GRSRADVRHIAVMHAFNLVRKALLSD"
     gene            complement(2677..3693)
                     /locus_tag="VU534_000432"
     CDS             complement(2677..3693)
                     /locus_tag="VU534_000432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HEU1513067.1"
                     /translation="MVKKIIGMVLALLSVTVVGVGVFAYTIYQQGTETLAKTYKKIGE
                     ETKVIEATEPLTILLMGVDTGNVERTETWVGRSDSMILMTVNPKTKKTTMMSLERDIL
                     TRIESGNGQAHEAKLNSAYADGGAELAIETIQKMMNIHIDRYVMVNMRGLQKLVDAVG
                     GITVNNILGFPISISDQEEFNTISIGVGEQHIGGEEALVYARMRYQDPEGDYGRQKRQ
                     REVIQKVMEKALSLNSIGHYQEILKALSDNMQTNIDLSAKSIPNLLGYKDSFKTIETQ
                     QLQGEGEILQGVSYQIVSRAHMLEMQNLLRRSLGQEEVTQLETNAVLFEDLFGRAPVG
                     DEDN"
     gene            complement(3701..4219)
                     /locus_tag="VU534_000433"
     CDS             complement(3701..4219)
                     /locus_tag="VU534_000433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU1513068.1"
                     /translation="MEYELLIREAEPKDAAELVAFLNRVSLETDFTSLDGDGILLTSE
                     EMEIFLNKQASSDNQITLLAFLNGKIAGIVNITADQRKRVRHIGDLFIVIGKRYWNNG
                     LGSLLLEEAIEWAQASGILRRLQLTVQTRNQAAVHLYQKHGFVIEGSQERGAYIEEGK
                     FIDVYLMGKLIG"
     gene            complement(4209..4652)
                     /gene="tsaE"
                     /locus_tag="VU534_000434"
     CDS             complement(4209..4652)
                     /gene="tsaE"
                     /locus_tag="VU534_000434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HEU1513069.1"
                     /translation="MYTKNEEELQALGERLGHLLAKNDVLILTGELGAGKTTFTKGLA
                     KGLQISQMIKSPTYTIVREYEGRLPLYHLDVYRIEGDADSIDLDEFIFGGGVTVIEWG
                     NLLGDALPDAYLELEILKEADGRRLNFQAKGLRAEKLLEELQYGV"
     gene            complement(4738..5358)
                     /locus_tag="VU534_000435"
     CDS             complement(4738..5358)
                     /locus_tag="VU534_000435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000839915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1513070.1"
                     /translation="MKSMRILFLLALIQISLSSCFLWKECILSFKQSTAFFIGSMVFV
                     SGICAGVNYLYTRKQEVHSVLASKKSVKLFYSMLLLINLLGAVLVLSDNLFIKNTLQQ
                     ELVDFLLPSFFFLFGLDLLIFLPLKKYVRDFLAMLDRKKTVLVTILATLLFLRNPMTI
                     VSLLIYIGLGLFFAAYLVPNSVKKEVSFYGHIFRDLVLVIVTLIFF"
     gene            complement(5741..6604)
                     /locus_tag="VU534_000436"
     CDS             complement(5741..6604)
                     /locus_tag="VU534_000436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU1513071.1"
                     /translation="MNTLAEKFRLKRKELRLSQQTLAEGICEQSQISKIERGHFIPSA
                     DLLFKLSQRLEVPLDYFFNEQIEVKSNLSNFKHLSARLLDDRNYDDLEYLYKIEVERS
                     TFLTLEDRTYLEWIKSIIDFYQYDSKCEAISSLENILLKVSSNTLIYLKALNTLSNFY
                     SLVGREQEYEANYSHLIELYQTKNLDHQEFLFGYIRVRYNYAHYLVSKEKYNEAIQEA
                     LETIELCKQRQTSYQLAPLLILVGNAGAKFLDREQVKNYYIEARELCKIYNNPLMLMK
                     IENYLKELDTV"
     gene            7069..7293
                     /gene="pneA1"
                     /locus_tag="VU534_000437"
     CDS             7069..7293
                     /gene="pneA1"
                     /locus_tag="VU534_000437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000181087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-peptide bacteriocin subunit PneA1"
                     /protein_id="HEU1513072.1"
                     /translation="MTNFNSNEKFCGKSLKSLSADEMSLIYGASDGAEPRWTPTPIIL
                     KSAAASSKVCISAAVSGIGGLVSYNNDCLG"
     gene            7300..7488
                     /gene="pneA2"
                     /locus_tag="VU534_000438"
     CDS             7300..7488
                     /gene="pneA2"
                     /locus_tag="VU534_000438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000786759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-peptide bacteriocin subunit PneA2"
                     /protein_id="HEU1513073.1"
                     /translation="MKNDFVIGKSLKELSLEEMQLVYGGTDGADPRSTIICSATLSFI
                     ASYLGSAQTRCGKDNKKK"
     gene            7604..10594
                     /gene="lanM"
                     /locus_tag="VU534_000439"
     CDS             7604..10594
                     /gene="lanM"
                     /locus_tag="VU534_000439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000875571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 lantipeptide synthetase LanM"
                     /protein_id="HEU1513074.1"
                     /translation="MKYKIKNVHKTLFIKERYQILSERNDNSLNNFSLNNWRSTMSII
                     SEKTFEEMLKLNNYNKKIFSNTVNYDYTEEQIRLYSEYAKNSEWYKFAEGSFEIFRKH
                     PQRINFKKDFSRILEPFIINLLKLINNYLENKEYEWIDKNGNIFSSLVFYLEDLIYPW
                     IVKPLVLEINSLREKGLLEGESEQQRYKYFITLFDKEENILNFYNKYPVLLRQISESC
                     LRFYTYFIEILSNLENDFSVLEEELGLRGKLNDIKFGKGDTHSQGKTVLILFFDDAKI
                     VYKPKNLIINNSLNTIAEYIRKVDEKIRIRIPRTIAYSDHSYEEFIDYLPLEQKKNLP
                     EYYYNFGVLLAFIYLFNGSDIHFENLISYGDMPVIIDFETMLQQPLFDDKTGQSLLDT
                     LFHRVTRTLLLPTEGVKREDGLDVEMSALTGNFKKDAFNGQVLINLNTDKVKFDIGKI
                     DFEGGKNLPVRDGDIEFDKYIKDFKKGFRDFYLIFEELNKTEEFKMLLKANLYGLKTR
                     VLFRDTNSYASVLSFLYHPDFYEEMLDREKALENLWSNKFSNQGIVASECEQMRLLDI
                     PIFYTDTNINEIYDDFGNHFISLHQFSGYDYFMKYLPNNNLENLEKQLDIIEIYFPSF
                     DQRKKGYKLNLSNRKKLPNESLVTILHNEVENIADSLVINNIYDEYPIWSIPVNFKGS
                     KWCLEQTGNDMYRGRAGILLFMYYVKLLKDKSSYTQLYNKMLSAIPPSVSLSKTTFGL
                     TGDIGYFIVLSIIEDYDTNTLACLNYIKSVLTELEKTDFASVSNKSDYINGLLPLINT
                     LVRYYRRGIEKERVLRLVLSLGDTLYNDVSERDNSNFGYSFGHGLSGVIFTLKNIYKV
                     TRLKKYKELILQLVPREKIKIHSLKWCSGEFGTLVNHPQSVPEGIVASLDNDTFCHGS
                     MAIINFYIDYMKEMDTSMELESLLCSVVMNKSKEGEYRIVQTSNFPDFSLYTGVTGIA
                     YTFLRYIALNQNDKKIVIPSLLEI"
     gene            10944..11648
                     /locus_tag="VU534_000440"
     CDS             10944..11648
                     /locus_tag="VU534_000440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001033172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HEU1513075.1"
                     /translation="MNKIFIYAGVRNHNSKTLEYTKRLSSIISSRNNVDISFRTPFNS
                     ELEISNSDSEELFKKGIDRQSNADDGGVIKKELLESDIIIISSPVYLQNVSVDTKNFI
                     ERIGGWSHLFRLAGKFVVTLDVAESNGSDNVSEYLRDIFSYMGGQILHQVSITNSLKD
                     IAEAQLMEATYKIEDVLEGKIKYKTTDYQERAYQTLKLILENYDSEHFEKMYWEKKRL
                     FEANSLEEWYYVENIK"
     gene            11629..12558
                     /locus_tag="VU534_000441"
     CDS             11629..12558
                     /locus_tag="VU534_000441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000912951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M50 family metallopeptidase"
                     /protein_id="HEU1513076.1"
                     /translation="MLKILNNSVIYLCLIPLLFLLLIIFPNDSLIYYFRLILISLISI
                     TLHELGHFLVGRCLSYKLEMLATPFFFYFRKKIYFKFPVLLAFGYCQMSNRNITNEKN
                     SDRNLVFYFFGGGGANLIVAILALLGFVPYASEFFILNIILFLVTVCLPIDGTDGNAI
                     REIVLYSKDSKTYQRFFANSLYNNPYITIDDFAKLTSKEKSFFSKFEKCLINLYFEVK
                     GEGSAFTIANHEVFDSNIQENIIHEYYKLLHKSSDWIIPQNLSLEEVVFTLSNYIYSK
                     NNKYLEKIKYLKKLVDFRQEEIIDFILNKEEVL"
     gene            12555..14663
                     /locus_tag="VU534_000442"
     CDS             12555..14663
                     /locus_tag="VU534_000442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase domain-containing ABC transporter"
                     /protein_id="HEU1513077.1"
                     /translation="MKIPMIYQMENSECGLACCAMILNYFKYEISLNELREIYPSSRS
                     GYSLLSISKVLGDFNISSHAFKASVRDLKPLSFPLICFWESSHFIILEKISKNKFYIL
                     DPAKGRQRMSISEFERHYSNIILTFKKLDSFMSRKDNKKSPVLKYFFKYRNKLGILFF
                     VTALLYVIQSLVPIANRYIIDTNFKDDSYSSRMLFTILFIFTVSFSLMYLLRQIYVAS
                     LKYIMDKEISYDFMKHLIYLPYSFYEKRTLGDILFRANSIVYIREILSNNFIAAILDL
                     LMIVVYAVVLFSFSKYMVIFLISLSLALSIVMYPIIKISKNLIDKNIKEKVNVQNITS
                     EVISKNSDIKLTGEEEFWINKWDNFNTKQLIIGRKLDIHLSIVSSITNVLQIILPVLT
                     LIVGVNIKTFEQLTLGQIVAISTVSPYFISPIISLSDNYIQLMLLKGYFLRIEDVFNT
                     KSELIPERVSQDIKFDKKIELKDIWYKYGLFDDYVLKGINVTIKKGETVAIVGESGSG
                     KSTLAKILLGLLEPNIGSIEVDGVEKEEIGQTLYRKIFGAVLQNSTLSYGTLRENLTF
                     GHFVSDEELMTNLNSIGLSNVVKSLPLGLETIIAEEGNNFSGGQQQMILLARCLLSKP
                     SVVVLDEATSSLDNLSQQITTSYLSEIGTTKILIAHRLDTIKSADKILVMHNGEIVEI
                     GTHRELLELGGIYKQLYSNN"
     gene            14687..16426
                     /locus_tag="VU534_000443"
     CDS             14687..16426
                     /locus_tag="VU534_000443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000699970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HEU1513078.1"
                     /translation="MKIMKKKYWTLAILFFCLFNNSVTAQEIPKNLDGNITHTQTSES
                     FSESDEKQVDYSNKNQEEVDQNKFRIQIDKTELFVTTDKHLEKNCCKLELEPQINNDI
                     VNSESNNLLGEDNLDNKIKENVSHLDNRGGNIEHDKDNLESSIVRKYEWDIDKVTGGG
                     ESYKLYSKSNSKVSIAILDSGVDLQNTGLLKNLSNHSKNYVPNKGYLGKEEGEEGIIS
                     DIQDRLGHGTAVVAQIVGDDNINGVNPHVNINVYRIFGKSSASPDWIVKAIFDAVDDG
                     NDIINLSTGQYLMIDGEYEDGTNDFETFLKYKKAIDYANQKGVIIVAALGNDSLNVSN
                     QSDLLKLISSRKKVRKPGLVVDVPSYFSSTISVGGIDRLGNLSDFSNKGDSDAIYAPA
                     GSTLSLSELGLNNFINAEKYKEDWIFSATLGGYTYLYGNSFAAPKVSGAIAMIIDKYK
                     LKDQPYNYMFVKKILEETLPVKNGIKVLNIPNVLRYDLNMLQLEYKNEQSWDSFIDNV
                     NLIELEERIQTTIGIKQINTHNIITIAREGYSQNYLPNTSENTYNSLQVSLVGVLLLF
                     ISMVNILWAKKSK"
     gene            16477..17244
                     /locus_tag="VU534_000444"
     CDS             16477..17244
                     /locus_tag="VU534_000444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HEU1513079.1"
                     /translation="MSQKMNHLDVGEFVLLLPEHLRSEEEHYKSVFEDDLTSRISSQD
                     ERQQMTATVGYLESGQDRFVYNTTPISYQQFLKDPIIIVITPQSTGPQSILFWIDAVQ
                     NYVLFNQLSDAQELIQRQGIENWVSEMQTGYHNYITLLDNIQRERWVMLAGAVLGIAT
                     SILLFNTMNRLYFEEFRRAIFIKRIAGLRFLEIHRTYLFAQLGVFLLGFVASVFLQVE
                     IGVAFLVLLLFTGLSLLQLHVQMQKENKMSMLVLKGG"
     gene            17246..17878
                     /locus_tag="VU534_000445"
     CDS             17246..17878
                     /locus_tag="VU534_000445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU1513080.1"
                     /translation="MIELKQVSKSFGERELFSNLSMTFEAGKVYALIGSSGSGKTTLM
                     NMIGKLEPYDGTIFYRGKDLANYKSSDFFRHELGYLFQNFGLIENQSIEENLKLGLIG
                     QKLSRSEQRLRQKQALEQVGLVYLDLDKRIFELSGGESQRVALAKIILKNPPFILADE
                     PTASIDPATSQLIMEILLSLRDDNRLIIIATHNPAIWEMADEVFTMDHLK"
     gene            complement(18824..19237)
                     /gene="ndk"
                     /locus_tag="VU534_000446"
     CDS             complement(18824..19237)
                     /gene="ndk"
                     /locus_tag="VU534_000446"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000438285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HEU1513081.1"
                     /translation="MEQTFFIIKPDGVKRGLVGEVLKRIEQRGFTIEKLEFRSQVSEE
                     LIDQHYQDLVGQSFYPPIREFMTSGPVLVGVISGPKVIETWRTMMGATRPEEALPGTI
                     RGDFAKAAGENEIIQNVVHGSDSEESAKREIALWF"
     gene            complement(19348..23025)
                     /gene="rpoC"
                     /locus_tag="VU534_000447"
     CDS             complement(19348..23025)
                     /gene="rpoC"
                     /locus_tag="VU534_000447"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000228741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HEU1513082.1"
                     /translation="MVDVNRFKSMQITLASPSKVRSWSYGEVKKPETINYRTLKPERE
                     GLFDEVIFGPTKDWECACGKYKRIRYRGIVCDRCGVEVTRTKVRRERMGHIELKAPVS
                     HIWYFKGIPSRMGLTLDMSPRALEEVIYFAAYVVIDPKDTPLEHKSIMTEREYRERLR
                     EYGYGSFVAKMGAEAIQDLLKQVDLEKEIAELKEELKTATGQKRVKAIRRLDVLDAFY
                     KSGNKPEWMILNILPVIPPDLRPMLQLDGGRFASSDLNDLYRRVINRNNRLARLLELN
                     APGIIVQNEKRMLQEAVDALIDNGRRGRPITGPGSRPLKSLSHMLKGKQGRFRQNLLG
                     KRVDFSGRSVIAVGPTLKMYQCGVPREMAIELFKPFVMREIVARDIVQNVKAAKRLVE
                     RGDERIWDILEEVIKEHPVLLNRAPTLHRLGIQAFEPVLIDGKALRLHPLVCEAYNAD
                     FDGDQMAIHVPLSEEAQAEARILMLAAEHILNPKDGKPVVTPSQDMVLGNYYLTMEEA
                     GREGEGMVFKDRDEAVMAYRNGYVHLHSRVGIATDSLNKPWTEEQRHKVLLTTVGKIL
                     FNDIMPEGLPYLQEPNNANLTEGVPAKYFLPLGGDIKEAISNLELNPPFKKKNLGNII
                     AEIFKRFRTTETSALLDRMKNLGYHHSTLAGLTVGIADIPVVDDKAEIIEESHKRVEQ
                     ITKQFRRGMITDDERYNAVTAEWRAAREKLEKRLIANQDPKNPIVMMMDSGARGNISN
                     FSQLAGMRGLMAAPNGRIMELPILSNFREGLSVLEMFFSTHGARKGMTDTALKTADSG
                     YLTRRLVDVAQDVIIREDDCGTDRGLLIRSIAEGKEMIESLEERLNGRYTKKTVKHPE
                     TGAVIIGPNELITEDKAREIVNAGVEEVTIRSVFTCNTRHGVCRHCYGINLATGDAVE
                     VGEAVGTIAAQSIGEPGTQLTMRTFHTGGVASNTDITQGLPRVQEIFEARNPKGEAVI
                     TEVKGQVTAIEEDASTRTKKVFVKGETGEGEYVVPFTARMRVEVGGQVARGAALTEGS
                     IQPKRLLAVRDVLSVETYLLGEVQKVYRSQGVEIGDKHIEVMVRQMIRKVRVMDPGDT
                     DLLMGTLMDINDFTDANKDVLIAGGVPATGRPVLMGITKASLETNSFLSAASFQETTR
                     VLTDAAIRGKKDHLLGLKENVIIGKIIPAGTGMARYRNLEPHAVNEEEYLNPPVEEEG
                     NEETTEVVVDTAVETVEETVE"
     gene            complement(23058..26669)
                     /gene="rpoB"
                     /locus_tag="VU534_000448"
     CDS             complement(23058..26669)
                     /gene="rpoB"
                     /locus_tag="VU534_000448"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000907130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HEU1513083.1"
                     /translation="MAGHDVQYGKHRTRRSFSRIKEVLDLPNLIEIQTDSFKAFLDHG
                     LKEVFEDVLPISNFTDTMELEFVGYEIKEPKYTLEEARIHDASYSAPIFVTFRLINKE
                     TSEIKTQEVFFGDFPIMTEMGTFIINGGERIIVSQLVRSPGVYFNDKVDKNGKVGYGS
                     TVIPNRGAWLELESDSKDITYTRIDRTRKIPFTTLVRALGFSGDDEIFDIFGDSELVR
                     NTVEKDIHKNPMDSRTDEALKEIYERLRPGEPKTAESSRSLLVARFFDPRRYDLAAVG
                     RYKINKKLNVKTRLLNQTIAEPLVDPETGEILVEAGTIMTRSVIESIESHLDGDLNKI
                     VYIPNDAAVVTEPVVLQKFKVIAPTDPDRVVTIIGNANPDDKVRTVTPADILAEMSYF
                     LNLAEGLGRVDDIDHLGNRRIRAVGELLANQVRLGLSRMERNVRERMSVQDNEVLTPQ
                     QIINIRPVTAAVKEFFGSSQLSQFMDQHNPLSELSHKRRLSALGPGGLTRDRAGYEVR
                     DVHYTHYGRMCPIETPEGPNIGLINNLSSYGHLNKYGFVQTPYRKVDRETGVVTNEIV
                     WLTADEEDEYTVAQANSRLNEDGTFAEKIVMGRHQGVNQEYPANIVDYMDVSPKQVVA
                     VATACIPFLENDDSNRALMGANMQRQAVPLINPQAPYVGTGMEYQAAHDSGAAVIAQY
                     DGKVTYADADKVEVRREDGSLDVYHIQKFRRSNSGTAYNQRTLVKVGDVVEKGDFIAD
                     GPSMENGEMALGQNPIVAYMTWEGYNFEDAVIMSERLVKDDVYTSVHLEEYESETRDT
                     KLGPEEITREIPNVGEDALKDLDEMGIIRIGAEVKEGDILVGKVTPKGEKDLSAEERL
                     LHAIFGDKSREVRDTSLRVPHGADGVVRDVKIFTRVNGDELQSGVNMLVRVYIAQKRK
                     IKVGDKMAGRHGNKGVVSRIVPVEDMPYLPDGTPVDIMLNPLGVPSRMNIGQVMELHL
                     GMAARTLGIHIATPVFDGASSEDLWSTVKEAGMDSDAKTILYDGRTGEPFDNRVSVGV
                     MYMIKLHHMVDDKLHARSVGPYSTVTQQPLGGKAQFGGQRFGEMEVWALEAYGASNVL
                     QEILTYKSDDINGRLKAYEAITKGKPIPKPGVPESFRVLVKELQSLGLDMRVLDEDDQ
                     EVELRDLDEGMDEDVIHVDDLEKAREKAAQEAKAAFEAEEAEKATKAEATEEAAEQE"
     gene            27085..27155
                     /locus_tag="VU534_000449"
     tRNA            27085..27155
                     /locus_tag="VU534_000449"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:27117..27119,aa:Cys,seq:gca)
     gene            complement(27353..28684)
                     /locus_tag="VU534_000450"
     CDS             complement(27353..28684)
                     /locus_tag="VU534_000450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HEU1513084.1"
                     /translation="MEDPSSQNLLLQFVLLFILTVLNAFFSATEMAMVSLNRARVEQK
                     AEEGDRRYIRLLKVLENPNHFLSTIQVGITLITILSGASLTDTLGRVIASWLGNGETA
                     QAVATFLSLAFLTYISIVFGELYPKRIALNLKDALAIRTAPIIIGIGKLVSPFVWLLA
                     ASTNFLSHLTPMSFDDADEKMTRDEIAYMLTNSEETLDADEIEMLQGVFSLDELMARE
                     VMVPRTDAFMVDIQDDSQAIIQSILKQNYSRIPVYDGDKDNVIGIIHTKSLLKAGFVD
                     GFDNIVWKRILQDPLFVPETIFVDDLLKELRNTQRQMAILLDEYGGMAGLVTLEDLLE
                     EIVGEIDDETDKAAIDVHQIGEDTYIVQGTMTLNDFNNYFDVELESDDVDTIAGYYLT
                     GVGTIPTTEKLSYELVSQNKQFILTNDKVKNGRVTKVKVQITEVEIEEETE"
     gene            complement(28913..29737)
                     /gene="endA"
                     /locus_tag="VU534_000451"
     CDS             complement(28913..29737)
                     /gene="endA"
                     /locus_tag="VU534_000451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-entry nuclease EndA"
                     /protein_id="HEU1513085.1"
                     /translation="MNKKTRQTLIGLLVLLLLSTGSYYIKQMPSAPNSPKTNLSQKKQ
                     ASEAPSQALAESVLTDAVKSQIKGSLEWNGSGAFIVNGNKTNLDAKVSSKPYADNKTK
                     TVGKETVPTVANALLSKATRQYKNRKETGNGSTSWTPPGWHQVKNLKGSYTHAVDRGH
                     LLGYALIGGLDGFDASTSNPKNIAVQTAWANQAQAEYSTGQNYYESKVRKALDQNKRV
                     RYRVTLYYASNEDLVPSASQIEAKSSDGELEFNVLVPNVQKGLQLDYRTGEVTVTQ"
     gene            complement(29776..29964)
                     /locus_tag="VU534_000452"
     CDS             complement(29776..29964)
                     /locus_tag="VU534_000452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HEU1513086.1"
                     /translation="MNKKSSYVVKRLLLVIIVLILGTLALGIGLMVGYGILGKGQDPW
                     AILSPAKWQELIHKFTGN"
     gene            complement(29957..31240)
                     /gene="murA"
                     /locus_tag="VU534_000453"
     CDS             complement(29957..31240)
                     /gene="murA"
                     /locus_tag="VU534_000453"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HEU1513087.1"
                     /translation="MDKIVVQGGDNRLVGSVTIEGAKNAVLPLLAATILASEGKTVLQ
                     NVPILSDVFIMNQVVGGLNAKVDFDEEAHLVKVDATGDITEEAPYKYVSKMRASIVVL
                     GPILARVGHAKVSMPGGCTIGSRPIDLHLKGLEAMGVKISQTAGYIEAKAERLHGAHI
                     YMDFPSVGATQNLMMAATLADGVTVIENAAREPEIVDLAILLNEMGAKVKGAGTETIT
                     ITGVEKLHGTTHNVVQDRIEAGTFMVAAAMTGGDVLIRDAVWEHNRPLIAKLLEMGVE
                     VIEEDEGIRVRSQLENLKAVHVKTLPHPGFPTDMQAQFTALMTVAKGESTMVETVFEN
                     RFQHLEEMRRMGLHSEIIRDTARIVGGQPLQGAEVLSTDLRASAALILTGLVAQGETV
                     VGKLVHLDRGYYGFHEKLAQLGAKIQRIEASDEDE"
     gene            complement(31264..31494)
                     /locus_tag="VU534_000454"
     CDS             complement(31264..31494)
                     /locus_tag="VU534_000454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014017351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1146 domain-containing protein"
                     /protein_id="HEU1513088.1"
                     /translation="MVQLLFTLSSHMFFIYVSFYLLKDLVRWEKVLKVTDDNTRKVRL
                     LVAFFSIVIGYILSSFFISLYHLWQEALRGLL"
     gene            complement(31552..32589)
                     /locus_tag="VU534_000455"
     CDS             complement(31552..32589)
                     /locus_tag="VU534_000455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PDZ domain-containing protein"
                     /protein_id="HEU1513089.1"
                     /translation="MKKKIRWPLYVIAALIVTFLAFVVPLPYYIEVPGGSEDIRQVLK
                     VNDTEDKEAGAYQFVTVGVQHATLAHMIYAWLTPFTDIRSAQETTGGSSDVEFMRINQ
                     FYMQTSQNMAKYQGLKTAGKDIELKYFGVYVLNVTDNSTFKGILNISDTVTAVNDQTF
                     DSSKDLIDYVSSQKLGDSVKVTYEEDGQTKSAEGKIITLENGKNGIGIGLIDRTEVIS
                     NVPISFSTAGIGGPSAGLMFSLAIYTQIAHPDLRNGRIVAGTGTIDRDGNVGDIGGID
                     KKVVASARAGAAIFFAPDNPVSEEEQKAHPDAKNNYQTALEAAKTIKTDMKIVPVKTL
                     QDAIDYLKNNP"
     gene            complement(32573..33061)
                     /gene="coaD"
                     /locus_tag="VU534_000456"
     CDS             complement(32573..33061)
                     /gene="coaD"
                     /locus_tag="VU534_000456"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HEU1513090.1"
                     /translation="MSDKIGLFTGSFDPMTNGHLDIIERASRLFDKLYVGIFFNPHKQ
                     GFLPLENRKRGLEKAVKHLGNVKVVSSHDKLVVDVAKRLGATCLVRGLRNASDLQYEA
                     SFDYYNHQLSSDIETIYLHSRPEHLYISSSGVRELLKFGQDIACYVPESILEEIRNEK
                     KD"
     gene            complement(33051..33590)
                     /gene="rsmD"
                     /locus_tag="VU534_000457"
     CDS             complement(33051..33590)
                     /gene="rsmD"
                     /locus_tag="VU534_000457"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006147838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HEU1513091.1"
                     /translation="MKIVSGIYGGRPLKTLEGKTTRPTSDKVRGAIFNMIGPYFEVGR
                     VLDLYAGSGGLSIEAVSRGMSSAVLVERDRKAQTIVAENIQMTKEVGKFQLLKMDAER
                     ALEQVSGEFDLVFLDPPYAKEQIVADIEKMAERELFSEDVMVVCETDKAVELPEEIAC
                     LGIWKEKIYGISKVTVYVR"
     gene            complement(33655..34647)
                     /locus_tag="VU534_000458"
     CDS             complement(33655..34647)
                     /locus_tag="VU534_000458"
                     /EC_number="6.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016502595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--ammonia ligase"
                     /protein_id="HEU1513092.1"
                     /translation="MKKSFIHQQEEISFVKNTFTQYLKDKLEVVEVQGPILSKVGDGM
                     QDNLSGVENPVSVKVLQIPDATYEVVHSLAKWKRHTLARFGFGEGEGLFVHMKALRPD
                     EDSLDATHSVYVDQWDWEKVIPNGKRNIVYLKETVEKIYKAIRLTELAVEARYDIESI
                     LPKQITFIHTEELVERYPDLTPKERENAICKEFGAVFLIGIGGELPDGKPHDGRAPDY
                     DDWTSESENGYKGLNGDILVWNESLGGAFELSSMGIRVDEETLRRQVEITGDEDRLEL
                     EWHKSLLNGLFPLTIGGGIGQSRMAMFLLRKRHIGEVQTSVWPQEVRDTYENIL"
     gene            complement(34759..35442)
                     /locus_tag="VU534_000459"
     CDS             complement(34759..35442)
                     /locus_tag="VU534_000459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015545711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HEU1513093.1"
                     /translation="MNHTIIHDRAGLNQFYAKVYAFVGLGIGLSALVSGLMLTVFQSQ
                     LVYLLMQGRLWLTIATFAELALVFVASSMASRNSPAALPVFLLYSVLNGFTLSFVVAF
                     YTPGTVLSAFVSSALLFFVMAAVGIFTKKDLSGIGRAMMAALIGLLIAMVVNIFLASG
                     FFDYMISVAMVLVFSGLIAWDNQKIRLAYEQSQGRVATGWVVSMALSIYLDFINLFLS
                     ILRIFGRND"
     gene            complement(35498..36238)
                     /locus_tag="VU534_000460"
     CDS             complement(35498..36238)
                     /locus_tag="VU534_000460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000152696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA methyltransferase"
                     /protein_id="HEU1513094.1"
                     /translation="MTIITSKANSVVKNTKKLHQKKYRKSAYLIEGWHLFEEAVQAGV
                     TIEKIFTLENYRDQLATFSQTVWVSEDILLDLADSQTPQGIVAVVQKEEVGQADLSQG
                     KFLFLEDVQDPGNVGTIIRTADAAGFTEVIVSDKSADIYSLKTLRSMQGSHFHLPIYR
                     MTSQALLDETKKVAIPVLATTLSKDSVDYRELPSIENFVLVMGNEGQGISPLMAESAD
                     QLVHISMKGQAESLNVAVAAGILIFHLS"
     gene            36272..36550
                     /locus_tag="VU534_000461"
     CDS             36272..36550
                     /locus_tag="VU534_000461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001174612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HEU1513095.1"
                     /translation="MQKVRMIAQGRVQGVGFRWGVYSLALEIGGITGRVWNNDDGTVE
                     ILAQADSSAIMAKFIQEIRKGPTPFSKVSYLDVKLSNFPPYPDFKIAN"
     gene            36628..37554
                     /gene="yidC"
                     /locus_tag="VU534_000462"
     CDS             36628..37554
                     /gene="yidC"
                     /locus_tag="VU534_000462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HEU1513096.1"
                     /translation="MKSIKRFALSAMGVAMLLVLTGCVNVDKTTGQPTGFIWNTIGAP
                     MAEAIKYFATDKGLGFGVAIIIVTIIVRLIILPLGIYQSWKATLHSEKMNALKHVLEP
                     HQTRLKEATTQEEKLEAQQALFAAQKEHGISMFGGVGCFPILLQMPFFSAIYFAAQHT
                     EGVAQASYLGIPLGSPSMILVACAGVLYYLQSLLSLHGVEDEMQREQIKKMIYMSPLM
                     IVVFSLFSPASVTLYWVVGGFMMILQQFIVNYIVRPKLRKKVREELAKNPPKASAFSK
                     PSGRKDVTPEQPTAITSKKKHKNRNAGKQRSR"
     gene            complement(37629..38423)
                     /gene="pflA"
                     /locus_tag="VU534_000463"
     CDS             complement(37629..38423)
                     /gene="pflA"
                     /locus_tag="VU534_000463"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001288284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate lyase-activating protein"
                     /protein_id="HEU1513097.1"
                     /translation="MSEETIDYGQVTGMVHSTESFGSVDGPGIRFIVFLQGCHMRCQY
                     CHNPDTWAMESNKSRERTVDDVLTEALRYRGFWGNKGGITVSGGEALLQIDFLIALFT
                     KAKEQGIHCTLDTCALPFRNKPRYLEKFDKLMAVTDLVLLDIKEINEEQHKIVTSQTN
                     KNILACAQYLSDIGKPVWIRHVLVPGLTDRDDDLIELGKFVKTLKNVDKFEILPYHTM
                     GEFKWRELGIPYSLEGVKPPTADRVKNAKQLMDTESYQDYMKRVHG"
     gene            complement(38549..39799)
                     /locus_tag="VU534_000464"
     CDS             complement(38549..39799)
                     /locus_tag="VU534_000464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000856498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HEU1513098.1"
                     /translation="MKTPFINREELEAIVAEFPTPFHLYDEKGIREKARAVNQAFSWN
                     KGFKEYFAVKATPTPAILKILQEEGCGVDCSSYVELLMSHKLDFLGSEIMFSSNNTPD
                     KEYAYARELGATINLDAFEDIEHLERVAGIPEIISCRYNPGGVFELGTDIMDNPGEAK
                     FGMTKDQLFEAFAILKEKGAKTFGIHSFLASNTVTHLYYPELARQLFELAVEIKEKLG
                     ISLDFINLSGGIGVNYHPDQEPNDIALIGEGVRKVYEEVLTSAGLGQVKIFTELGRFM
                     LAPHGALVTRVTHKKETYRTYLGVDASAVNLMRPAMYGAYHHISNVTHPDGPAEVVDV
                     VGSLCENNDKFAVNRELPHTEIGDLLVIHDTGAHGFSMGYQYNAKLRSAEILYTEEGK
                     ARQIRRAERPEDYFATLYGFDFEE"
     gene            complement(39866..40693)
                     /gene="purR"
                     /locus_tag="VU534_000465"
     CDS             complement(39866..40693)
                     /gene="purR"
                     /locus_tag="VU534_000465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004242125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HEU1513099.1"
                     /translation="MKLRRSDRMVVISNYLINNPYKLTSLNTFAEKYESAKSSISEDI
                     VIIKRAFEEIEIGHIQTVTGAGGGVIFTPSISSQDAKEMVEDLRTKLSESDRILPGGY
                     IYLSDLLSTPAILKNIGRIIAKSFMDQKIDAVMTVATKGVPLANAVANVLNVSFVIVR
                     RDLKITEGSTVSVNYVSGSSGDRIEKMFLSKRSLKAGSRVLIVDDFLKGGGTVNGMIS
                     LLREFDSELAGVAVFADNAQEEREKQFDYKSLLKVTNIDVKNQAIDVEVGNIFDEDK"
     gene            complement(40960..41901)
                     /locus_tag="VU534_000466"
     CDS             complement(40960..41901)
                     /locus_tag="VU534_000466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exoribonuclease YhaM family protein"
                     /protein_id="HEU1513100.1"
                     /translation="MKISHMKKDELFEGFYLIKSADLRQTRAGKNYLAFTFQDDSGEI
                     DGKLWDAQPHNIEAFTAGKVVHMKGRREVYNNTPQVNQITLRLPQAGEPNDPADFKVK
                     SPVDVKEIRDYMSQMIFKIENPVWQRIVRNLYTKYDKEFYSYPAAKTNHHAFETGLAY
                     HTATMVRLADAISEVYPQLNKSLLYAGIMLHDLAKVIELTGPDQTEYTVRGNLLGHIA
                     LIDSEITKTVMELGIDDTKEEVVLLRHVILSHHGLLEYGSPVRPRIMEAEIIHMIDNL
                     DASMMMMSTALALVDKGEMTNKIFAMDNRSFYKPDLD"
     gene            complement(41891..43147)
                     /locus_tag="VU534_000467"
     CDS             complement(41891..43147)
                     /locus_tag="VU534_000467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000444769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA recombination protein RmuC"
                     /protein_id="HEU1513101.1"
                     /translation="MESLLILLLIANLAGLFLIWQRQDRQEKHLSKSLEDQADHLSDQ
                     LDYRFDQARQASQLDQKDLEVVVSDRLQEVRIELHQGLTQVRQEMTDNLLQTRDKTDQ
                     RLQALQESNEQRLEQMRQTVEEKLEKTLQTRLQASFETVSKQLESVNRGLGEMQTVAR
                     DVGALNKVLSGTKTRGILGELQLGQIIEDIMTPAQYEREYATVENSSERVEYAIKLPG
                     QGDQEYVYLPIDSKFPLADYYRLEEAYETGDKDEIERCRKSLLASVKRFARDIRNKYI
                     APPRTTNFGVLFVPTEGLYSEIVRNPVFFDDLRREEQIIVAGPSTLSALLNSLSVGFK
                     TLNIQKSADHISKTLASVKTEFGKFGGILVKAQKHLQHASGNIDELLNRRTIAIERTL
                     RHIELSEGEPALDLLHFQENEEEYED"
     gene            complement(43149..43811)
                     /locus_tag="VU534_000468"
     CDS             complement(43149..43811)
                     /locus_tag="VU534_000468"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000006147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HEU1513102.1"
                     /translation="MSEYKLSENNWTRVAVFAGGNRGHYRTDFDAFVGVDRGSLWVLE
                     EDLPLALAVGDFDSVTEEERQVIQKGAQYFVQARPEKDDTDLELALLTIFEQNPQAQV
                     TIFGALGGRIDHMLANVFLPSNPKLAPYMHQIEIEDGQNLITYCPEGISQLEPRSDYD
                     YLAFMPVRDSQLTILGAKYELTEENFFFKKVYASNEYIDREVSVTCPDGYVVVLHSKD
                     RR"
     gene            complement(43774..44430)
                     /locus_tag="VU534_000469"
     CDS             complement(43774..44430)
                     /locus_tag="VU534_000469"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HEU1513103.1"
                     /translation="MSQYKIAPSILAADYANFEREIKRLEATGAEYAHIDIMDSHFVP
                     QISFGAGVVESLRPHSKMVFDCHLMVSNPEHHLEDFARAGADIISIHVEATPHIHGAL
                     QKIRSLGVKPSVVINPGTSVEAIKHVLHLVDQVLVMTVNPGFGGQAFLPETMDKVREL
                     VALREEKGLNFEIEVDGGIDDQTIAQAKEAGATVFVAGSYVFKGEVNERVQTLRKQLD
                     "
     gene            complement(44441..45319)
                     /gene="rsgA"
                     /locus_tag="VU534_000470"
     CDS             complement(44441..45319)
                     /gene="rsgA"
                     /locus_tag="VU534_000470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HEU1513104.1"
                     /translation="MQGQIIKALAGFYYVESDGQVYQTRARGNFRKKGHTPYVGDWVD
                     FSAEENSEGYILKIHERKNSLVRPPIVNIDQAVVIMSVKEPDFNSNLLDRFLVLLEHK
                     GIHPIVYISKMDLLEDRGELDFYQQTYGDIGYDFVTSKEELLSLLTGKVTVFMGQTGV
                     GKSTLLNKIAPDLNLETGEISDSLGRGRHTTRAVSFYNLNGGKIADTPGFSSLDYEVS
                     RAEDLNQAFPEIATVSRDCKFRTCTHTHEPSCAVKPAVEEGVIATFRFDNYLQFLSEI
                     ENRRETYKKVSKKIPK"
     gene            complement(45321..46193)
                     /gene="rsmA"
                     /locus_tag="VU534_000471"
     CDS             complement(45321..46193)
                     /gene="rsmA"
                     /locus_tag="VU534_000471"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HEU1513105.1"
                     /translation="MRIADYSVTKAVLERHGFTFKKSFGQNFLTDTNILQKIVDTAEI
                     DDQVNVIEIGPGIGALTEFLAERAAQVMAFEIDHRLVPILADTLRDFDNVTVVNEDIL
                     KVDLAQHIQNFKNPDLPIKVVANLPYYITTPILMHLIESGIPFCEFVVMMQKEVADRI
                     SAQPNTKAYGSLSIAVQYYMTAKVAFIVPRTVFVPAPNVDSAILKMVRRPEPAVAVED
                     ENFFFKVSKASFTHRRKTLWNNLTGYFGKTEEVKDKLTKALDQAGLSPSVRGEALSLA
                     EFAGLADALKGQGL"
     gene            complement(46324..46632)
                     /locus_tag="VU534_000472"
     CDS             complement(46324..46632)
                     /locus_tag="VU534_000472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000333253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1513106.1"
                     /translation="MCEKIRIRRVSDYPSARGGLEDILIMENMTNHLLLVQIRVHGYL
                     LDFASIEGQRQKHYRLKNLPQTVELTVDDVEEDVDLTLPENRSYQEADFFERMFRENC
                     "
     gene            complement(46625..47266)
                     /locus_tag="VU534_000473"
     CDS             complement(46625..47266)
                     /locus_tag="VU534_000473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU1513107.1"
                     /translation="MIDIQGLEKKFNDRAIFSGLNLKLEKGKVYALIGKSGSGKTTLL
                     NILGKLEKIDGGRVLYQGKDLKTIPTREYFRDQMGYLFQNFGLLENQSIKENLDLGFV
                     GQKISKVERLERQVGALEKVNLGYLDLEQKIYTLSGGEAQRVALAKTILKNPPLILAD
                     EPTAALDPENSEEVMNLLVDLKDENRIIIIATHNPLVWNKADEIIDMRKLAHV"
     gene            complement(47268..49298)
                     /locus_tag="VU534_000474"
     CDS             complement(47268..49298)
                     /locus_tag="VU534_000474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000825281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HEU1513108.1"
                     /translation="MKRLFILISMVLVSLYMVITSVDHREEILFGNYPSVDVTGMMIN
                     QPVASREEVTEALSHLAVEHNSLIARRIVEPNEAGETRFTYATYGEGKLPEGLTISSK
                     ESAETSDLLGSYLIVSGSLDGVSLQTTLKELGYQGFVSNGEDPFSIVLLLTATPMVLL
                     SLAIFLLTFMSLTLIYRIKSLRQAGIRLIAGESLFGVALRPVLEDVRQLICSVLVSSL
                     LGLGILWYQGALFMATVQLVIIALLLYGLTLAGISTLLSVVYLLGLQENSLVDLLKGK
                     LPLKRMMTLMMVGQLLAVLVVGSSATALLPHYREMQEMERASNKWSQSSDRYRLSFGW
                     SSAFADEEGTRKDNREWQTFTEERLANTDSFYIMSNVDNFSDGAEVDLDGNRLSDYTP
                     SGNVIYVSPRYLIEEKITVSSEFMDKMQNLSEGEFGLILPESLREQSVYYQGLFTDYL
                     QNFSSESVEVTSQKHYLPQVRLAFTETGQERFLYNDGYKTTRQYLKDPIIVVLTPQAT
                     GTRPVAGMLWGTTANSALKLDRYGDSITALKEKGLYHKVSYLVKSQLFFAKVLNDKRV
                     EFYSLLIGTILTLSTAILLFDSMNLLYFEQFRRELMIKRLAGMTIYELHGKYLLAQGG
                     VLLLGLVLSSILTRDGLISALVVALFTLNALLILVRQDKKEEAGSMAVLKGK"
     gene            complement(49567..50466)
                     /locus_tag="VU534_000475"
     CDS             complement(49567..50466)
                     /locus_tag="VU534_000475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000904853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU1513109.1"
                     /translation="MLIGQKIKEIRIEKGISRPDFCGDEQELTVRQLSRIESGASQPS
                     LPKLDYIARRLGVPVYSLMPDFSALPSAYLELKYQILREPIYGKEEEYDKKEACLEEI
                     YKTYFDNLPKEEQLACEVLQACLDTSRTRRPEYAELILEEHMPQIIEKEAYSINDMLL
                     IRLFFYQMLIRKDLAKFINQIEKLMLFLLEQKKVTQIENYFIIRDTLISGMCCLEKVG
                     VTDCFNDYLSCLQEIMDKTQDYQKKPLVFMFLWKQALREERDFSLAESFYQSSKTFAQ
                     LIGDEFLVKKLTEEWQEDVKKYL"
     gene            complement(50538..51098)
                     /gene="rnmV"
                     /locus_tag="VU534_000476"
     CDS             complement(50538..51098)
                     /gene="rnmV"
                     /locus_tag="VU534_000476"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000660004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HEU1513110.1"
                     /translation="MKEKISQVIVVEGRDDTVNLKRYFDVETYETRGSAINAQDIERI
                     QRLHQRHGVIVFTDPDFNGERIRRMIMMVIPTVQHAFLKRDEAVPKSKTKGRSLGIEH
                     ASYEDLKTALAQVTEQFEHESQFDISRSDLIRLGFLAGADSRKRREYLGETLRIGYSN
                     GKQLLKRLELFGVTLAEVEEAMKSYE"
     gene            complement(51098..51871)
                     /locus_tag="VU534_000477"
     CDS             complement(51098..51871)
                     /locus_tag="VU534_000477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000575597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HEU1513111.1"
                     /translation="MIFDTHTHLNVEEFAGREAEEIALAAEMGVTQMNIVGFDKPTIE
                     HALELVDEYEQLYATIGWHPTEAGTYTEEVEAYLLDKLKHSKVVALGEIGLDYHWMTA
                     PKEVQEQVFRRQIQLSKDLDLPFVVHTRDALEDTYEIIKSEGVGPRGGIMHSFSGTLE
                     WAEKFVDLGMTISFSGVVTFKKATDLQEAAKELPLDKMLVETDAPYLAPVPKRGRENK
                     TAYTRYVVDFIADLRGMTTEELAVATTANAERIFGLDSK"
     gene            complement(52176..53069)
                     /locus_tag="VU534_000478"
     CDS             complement(52176..53069)
                     /locus_tag="VU534_000478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001816585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1542 domain-containing protein"
                     /protein_id="HEU1513112.1"
                     /translation="MVAQDPKAQDSTKLTAEKSTVKAPAQRVDVKDITHLTDEEKVKV
                     AILQANGSALDGATINVAGDGTATITFPDGSVVTILGKDTVQQSAKGESVTQEATPEY
                     KLENTPGGDKGGNTGSSDANANEGGGSQAGGSAHTGSQNSAQSQASKQLATEKESAKN
                     AIEKAAKDKQDEIKGAPLSDKEKAELLARVEAEKQAALKEIENAKTMEDVKEAETIGV
                     QAIAMVTVPKRPVAPNAAPKTTSAPQATAGTMQDVTYQSPAGKQLPNTGSASSAALAS
                     LGLVVATSGFALLGRKTRRRK"
     gene            complement(53353..53487)
                     /gene="rpmH"
                     /locus_tag="VU534_000479"
     CDS             complement(53353..53487)
                     /gene="rpmH"
                     /locus_tag="VU534_000479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HEU1513113.1"
                     /translation="MKRTYQPSKLRRARKHGFRNRMSTKNGRRVLAARRRKGRKVLAA
                     "
     gene            complement(53632..54846)
                     /locus_tag="VU534_000480"
     CDS             complement(53632..54846)
                     /locus_tag="VU534_000480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEU1513114.1"
                     /translation="MKEYNKSSKLEHVAYDIRGPVLEEAMRMRANGEKILRLNTGNPA
                     EFGFTAPDEVIHDLIMNARDSEGYSDSKGIFSARKAIMQYCQLKKFPNVDIDDIYLGN
                     GVSELIVMSMQGLLDNGDEVLVPMPDYPLWTAAVSLAGGNAVHYICDEAVEWYPDIDD
                     IKSKITSNTKAIVLINPNNPTGALYPKELLLEIIEIARQNDLIIFADEIYDRMVMDGH
                     VHTPVASLAPDVFCVSMNGLSKSHRIAGFRVGWMVLSGPKTHVKGYIEGLNMLSNMRL
                     CSNVLAQQVVQTSLGGHQSVDELLLPGGRIYEQRNFIYNAIQDIPGLSAVKPKAGLYI
                     FPKIDRNMYRIDDDEQFVLDFLKQEKVLLVHGRGFNWQEPDHFRIVYLPRVDELAQIQ
                     EKMTRFLKQYRR"
     gene            complement(55002..55296)
                     /locus_tag="VU534_000481"
                     /pseudo
     CDS             complement(55002..55296)
                     /locus_tag="VU534_000481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009014348.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            55458..55910
                     /locus_tag="VU534_000482"
     CDS             55458..55910
                     /locus_tag="VU534_000482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000079155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HEU1513115.1"
                     /translation="MAQRYQNIMVAIDGSKEADLAFVKGVHSALRNDAKLTIAHVIDT
                     RALQSVSTFDAEVYEELQVDAESLMKEYEKRAKDAGVADVHIVIEMGNPKTLLARTIP
                     DAEEVDLILVGATGLNAFERLLVGSSSEYILRHAKVDLLVVREQEKTL"
     gene            complement(55945..57333)
                     /locus_tag="VU534_000483"
     CDS             complement(55945..57333)
                     /locus_tag="VU534_000483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000453140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEU1513116.1"
                     /translation="MEVKAVFFDIDGTLVNNRKSVLKSTKDAIKIVKEQGVLVGVATG
                     RGPFFVKELMDDLDLDFAVTYNGQYIFSKDRVLFTSPISKLHLRHLISYAKKEGTEIA
                     LGTKDAMLGSKIMSFGLGSFSQRISRFVPSVLTRTVSQSFNRMVSKVVPQKEEDLLHL
                     MNQPIYQVLMLMTPEESEKAAADFEDLKLTRSNPFASDVINQGNSKLEGIRRVGKEYG
                     FDLNQVMAFGDSDNDLEMLAGVGMSVAMGNGSSSVKEAAKHITTSNQQDGIHKALEHF
                     GVLSSEKVFVSRDYHFNKVKTFHHMMDERTQEEPRAWDLEGATHRAGFKIEELVEFVR
                     AASPSEEDFGQAVSQLHQALDKAADKVAKKTPAQQDLIGQVDALIDTLYFTYGSFVLM
                     GVDPERIFDIVHQANMGKIFPDGKAHFDPVTHKILKPDNWEEKYAPEPAIKKELQRQL
                     KAYERHKERNKS"
     gene            57399..58361
                     /locus_tag="VU534_000484"
     CDS             57399..58361
                     /locus_tag="VU534_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HEU1513117.1"
                     /translation="MPKKILVLHTGGTISMQADASGAVVTSSDNPMNHVSNPLEGIQV
                     HALDFFNLPSPHIKPKHMLVLYQKIKEEADNYDGVVITHGTDTLEETAYFLDTMEVPH
                     MPIVLTGAMRSSNELGSDGVYNYLSALRVASDDRAADKGVLVVMNDEIHAAKYVTKTH
                     TTNVSTFQTPTHGPLGLIMKQEILYFKTAEPRVRFDLDHIQGLVPIISAYAGMTDELI
                     DMLDLEHLDGLIIQAFGAGNIPKETAQKLESLLQKGIPVALVSRCFNGIAEPVYAYQG
                     GGVQLQKAGVFFVKELNAQKARLKLLIALNAGLTGQALKDYMEG"
BASE COUNT        17469 a        12323 c        10899 g        17742 t
ORIGIN      
        1 taatttgact ttcctaatag agttgttcat atcttatttc aagctactat atataatcta
       61 aaaacttgaa tcaaaaatcg aaaaagtagc ggatttctcc actgctttaa cagcttattc
      121 ttcaatttcg atttcaagtt catcgcctaa gtcaagcgga acttcttcat tcactgcttc
      181 ttctttcttt ggctcatctt ttttgttttc agtatcttgt tctgaaactt cttctccatc
      241 aatcaagcca aatttagaac ggacttgctt atcaatttca tcaaagattt ctgggtgctc
      301 tgccaagtat ttcttagcat tctcagaacc ttgcccaatt ttttcatctt tgtaagaata
      361 ccaagcccct gcttttttga taatatccaa atcgcttgca atcttcaaaa gctcaccagt
      421 cttagaaatt ccttctccgt acataatttc aactacggct tccttaaacg gtggagctac
      481 cttatttttt acaaccttaa tcttagtttc tttaccgaca ttggtttctt tttggtcacc
      541 agttccctta atttgtgtat taccacgaac atccaagcgg actgaagcat agaatttcaa
      601 agcacgtccg cccggtgttg tttctggatt tccaaacatc actccaactt tttcacgcaa
      661 ttggttgata aaaatggcaa ttgttttggt tttattgata gaggcgccaa gtttacgcat
      721 ggcctggctc atcatacgag cctgcaaacc aacatggcta tctccgatat ctccatcaat
      781 ttccgcacga ggaacaaggg cagcaactga gtcgactacg acaagatcaa ctgcacctga
      841 gtcaatcaat tttcccgcaa tctcaagacc ttgctctcct gagtctggtt gagacaagag
      901 caattcgtca atattgacac caagggccgc agcataagct ggatcaaggg catgttccgc
      961 atcgataaag gcagcaatcc caccttcttt ttgcgcttgt gcaactgcat gaagggcaac
     1021 cgttgtctta ccagatgact ctgggccata gatttcgatg atacgtccct taggataacc
     1081 acctgagcca agggcaatgt caagagctaa agaacctgag ctcatcactt gcaccttttg
     1141 ctccgcacgt tcacccaaac gcatgattga tcctttacca aagtctttct caatcaattt
     1201 aagagcgtca ttcaaggcct tttcacgttc tgccccaaat ttttttgaaa tttcttctaa
     1261 tttttttggt tttttcgcca ttctattctc ctacattcta atgatcctca gacctatcta
     1321 ctattatatc aaaagttagt cacttaataa agccttgcga actaggttaa aggcatgcat
     1381 aaccgcaatg tgacgtacat ctgctcggct tctgcctcca atattaacct tgataacctc
     1441 agttccttga tcttgcgcca agcctatgaa gactgtccca actgggtgtc cttctaggct
     1501 atctggtcct gccactccag tcaaactaat tccaaaatca gactgggtct tgcttcgtgc
     1561 ctgctcagcc atcttctgag ctgtaaattc agacaccaca ccatgttctt ccaaattctt
     1621 ggcaggaata tccaacatcc ttgatttttc ctccaagcta taggtcacaa aaccaccctt
     1681 aaatatactt gaaactccag aaaaattcgc cacggtagct tggaaaagac ctgccgtcaa
     1741 actctctgca gccgcgatgg ttttcccttg ccttttcagt tcttctacca caatgctggc
     1801 taaactagtt tcttccccat aaccatagca aaagtctcgt aaagaaattc cttcgaaagt
     1861 ctggcagtcc aagatttgat tttccaagat atccagcgct tgattcgcct cttcttgact
     1921 gctagccttt gttgacagac gtagagtgac ttctcctgtc ttggcataag gggccaaggt
     1981 aggatcgatc tgattatcaa ttaaatcagc caaaatcgta accaactggc tctcgccaat
     2041 cccaaagaaa cgaagaactc gggaatacag cttgctccct gtcatcaact tgggtagaag
     2101 ttggtttaag accatgggtt tcaattcact tggcggacct ggaaggacga cataggtcac
     2161 tccgtctact tctaattttc ctccaacagc cagtcctgtt tcgtttggca gtggaatcgc
     2221 tccttctaca atttgagctt gtctttcgtt attcggtgtt cgggcatagt ctggtcgcag
     2281 ggtaaaaaag atatccaact tctcctgagc ctgaggatca aagactaatg ctttccctaa
     2341 aaatttagct agggtttgtt tggttaggtc gtcctcagtt ggccccaaac cgcctgtcaa
     2401 aatcaccaga ctgctacgtt gactggcaat ctcaagcaaa gacaagagac gaacttcatt
     2461 gtctcctaca gccgtctgaa aatatacatc taccccaatc tcagctagtt tttccgacaa
     2521 aaactgggca ttggtgttga caatctgccc tgtcaaaatc tctgttccaa cagcaatgat
     2581 ttctgctttc atgtttcctc ctacctatct attcgtattt ttttgaaaaa atcgcaggaa
     2641 ttttcctacg attgattttt ttatttgtat caaaagttaa ttatcttcat caccaacagg
     2701 tgctctgcca aataaatctt caaataaaac cgcattggtt tcaagctgag taacttcttc
     2761 ttgtcccaaa gaacgtcgga gtagattttg catttccaac atatgtgctc tcgaaacaat
     2821 ctggtaagaa acaccttgaa gtatctctcc ttcaccctgc aactgctgag tttcaatggt
     2881 tttaaatgaa tctttatagc ctagcaagtt agggatactt tttgcagaca aatcaatatt
     2941 ggtctgcata ttgtcactca aagcttttag aatctcttga taatgaccaa tgctatttaa
     3001 actgagagct ttttccatga ctttttgaat aacttcacgt tgacgttttt gacgaccata
     3061 atccccctca ggatcttggt aacgcattcg tgcatagact agggcttctt ctcccccaat
     3121 atgttgctcc ccaacaccga tagaaatagt attaaattct tcttggtcac tgatagaaat
     3181 tgggaaacct aggatattat tgactgtaat acctcctact gcatccacta gtttttgcaa
     3241 tcctctcata ttgaccatca catagcgatc aatatggata ttcatcattt tttgaatggt
     3301 ttctatagca agctctgctc caccatctgc atatgctgag ttcagtttcg cttcatgagc
     3361 ctgaccattc cctgattcaa tgcgcgtcag aatatcccgc tctaaactca tcattgttgt
     3421 ttttttcgtt ttaggattca ctgtcatcaa gatcatgcta tcacttctac cgacccaagt
     3481 ttcagttcgt tcaacatttc cggtgtccac tcccattaac agaatggtta gaggttcagt
     3541 cgcttcaata accttggttt cttcaccgat ttttttatag gttttagcta aggtttctgt
     3601 cccttgttga taaatagtat aagcaaaaac acctactcct actacagtta cagaaagtaa
     3661 agctagcacc attccaataa tttttttaac catatttcta ctaacctatc agtttaccca
     3721 tcaagtaaac atcgataaat ttcccttctt ctatatatgc cccacgctct tggctacctt
     3781 caatgacaaa gccatgcttt tgataaagat ggactgctgc ttgattacga gtttggacag
     3841 tcagttggag acgacgcaga atgccacttg cttgtgccca ctctatcgct tcttctagca
     3901 acaaacttcc caagccatta ttccaatatc tttttccaat cacaatgaag agatctccaa
     3961 tatgacggac tctcttacgc tgatcagctg taatatttac aataccagca attttgccat
     4021 ttaagaatgc aagtaaggtt atctgattgt ccgaactagc ttgcttgttg aggaatattt
     4081 ccatctcctc actagtcaag agaataccat ctccgtctag gctggtaaag tctgtctcca
     4141 aactcacacg atttaaaaag gccactaatt cagctgcatc tttgggctct gcttccctaa
     4201 tgagcaattc atactccata ttgaagctcc tctaacaatt tctcagcacg caaacccttt
     4261 gcctgaaaat ttaaacggcg tccatctgct tcttttagaa tttccaattc taaataagca
     4321 tctggcaagg catctcctaa gagatttccc cactcaataa cagtcacgcc gccaccaaag
     4381 ataaactcat ccaagtcgat agaatcagca tctccttcaa tacgataaac atctaggtga
     4441 taaagtggaa gtcgaccttc atactctctc acgatagtat aggtgggact tttaatcatt
     4501 tgagaaatct gtaatccttt tgcaagtcct ttagtaaagg tcgttttacc tgcacccagt
     4561 tctccagtta agattaaaac atcattcttt gctaatagat ggcccaaacg ctcccctaag
     4621 gcttgcaact cttcttcatt ttttgtgtac atactcttat tataccaaaa acttttcttt
     4681 tgtgtctatt ttcctactaa acttatcatc ataacatcca taaaaaacag gctttctcta
     4741 aaagaaaatg agcgtaacaa tgaccaatac aagatctcgg aaaatatgac cataaaagga
     4801 aacttccttc ttaaccgaat ttgggacaag ataggctgca aaaaacaagc ccagtccaat
     4861 ataaatcaga agtgagacaa tggtcattgg atttcttaag aaaagaagtg ttgctaaaat
     4921 agtcaccaac actgtctttt ttctgtccag catagcaaga aaatcgcgca cgtatttttt
     4981 caagggtaaa aaaatcagca aatctagccc aaataggaaa aagaaggatg gcaataaaaa
     5041 gtcaactaat tcttgctgca gcgtattttt gatgaacaag ttatctgaca aaacaagaac
     5101 agctcctaac aaattaatta agagtaacat actgtaaaaa agcttcaccg acttcttact
     5161 ggctaggaca ctatggactt cttgcttacg ggtataaaga taatttactc cagcacagat
     5221 tcctgaaacg aaaaccatgc ttccgatgaa aaaagctgta ctttgtttaa aggacaagat
     5281 gcattccttc cataggaaac agctactcaa actgatttga attaaagcta acaaaaataa
     5341 gattctcatt gatttcatct tctctctccc ttcctaccaa tcattatact aggagaaaag
     5401 agagaactgt ttctaatctt ctcaaatgtc tctttaagac gctaaacaaa cactagagac
     5461 taatactcaa tgaaaatcaa agatcaaact aggtagctag ccacaggttg ctcaaaacag
     5521 tgttttgaga ttgcagatag agctgacgtg atttgaagag attttcgaag aatataaatt
     5581 tgaaatcatg aaaatccgtc aaacgggtgg ttgttttgtc tcgcacctca cggagcgaga
     5641 cggactcaga gtcacataat tataaggctg atagtattaa tctaactatc agccttacag
     5701 gttatttaac gtttcagaaa aactataatg tcaagattaa ctaaacagta tctagttcct
     5761 tcaaataatt ttctatcttc atcaacatta aaggattgtt ataaatctta cataactctc
     5821 ttgcttctat ataataattt ttgacttgtt ctctgtctag aaatttggct ccagcatttc
     5881 ctacaagaat aagtagagga gccaattggt agcttgtctg tctttgttta cagagttcaa
     5941 tcgtttcaag agcttcttgg atggcttcat tatatttttc ctttgatact aggtagtgag
     6001 cgtagttgta acgaactctg atgtagccaa ataaaaactc ttgatggtcc aaattttttg
     6061 tctgatacaa ctctattaaa tgagagtagt ttgcctcata ttcttgttca cgacccacta
     6121 aggaatagaa attagataga gtattcaacg cctttaaata aatcagagta tttgaagaga
     6181 cttttaataa tatattttcc aatgacgaaa ttgcctcaca cttactgtca tattgataga
     6241 agtcaattat agatttaatc cattcaaggt aagttcggtc ttctaatgtt agaaaagtgc
     6301 ttcgttctac ttctatttta taaagatatt ctaaatcgtc ataatttctg tcatctaata
     6361 ggcgagcaga tagatgtttg aaattagaga ggttagactt aacttcgatt tgttcattga
     6421 aaaagtaatc caaagggact tcaagtcgtt gagagagttt gaataacaag tctgcggagg
     6481 gaataaaatg acctctttca attttactaa tctggctttg ttcacaaatt ccttctgcaa
     6541 gagtttgttg ggagagtctc aactcttttc ttttcaatct gaatttctct gcgagtgtat
     6601 tcattaaaga taataaacct tcctatttgc ttaatttcat tataaagttt ttagttcaaa
     6661 atagcaagtt aaaggaataa ataattcttt atggtaataa acaaaaaaaa aagttaaaaa
     6721 ttacataaaa atacttgact aaataaaata tatctgttag aataaaaaca aggaaaaaga
     6781 aaggggtttc attgcatgag aaaaaaacgt ggaattaaaa aattagttac atttgcattg
     6841 ctaggtgttt ttatgtttag taatacaatt ccttaccaac agtttattca gaagaataaa
     6901 caattggaga ttcgagtgca atcgcaaaag aagtccaatg gtcttgatgt tgggaaggcg
     6961 gattaaaacc cgatattttg cacgagaatg agagaattat aatttatctg aaaaaacgaa
     7021 aaatatagag caacttattt aactttttat aaggaggagt tattacttat gaccaacttt
     7081 aattcaaacg aaaaattttg tggaaaaagt ttaaaatcat tgtctgctga tgaaatgagt
     7141 ttaatttatg gtgcatctga tggtgcagag ccacgttgga cgcctactcc tattattttg
     7201 aaatcagctg cagctagctc gaaagtatgc attagtgcag ctgtttctgg tattgggggg
     7261 ctagttagct acaataatga ttgtttgggg taaattaaaa tgaaaaatga ttttgtaatc
     7321 ggaaagagtt tgaaagaatt atctcttgaa gaaatgcaat tggtttatgg tggcacagat
     7381 ggtgctgacc ctagatcaac aattatatgt tctgctacat taagttttat tgcatcatat
     7441 ttggggtcag ctcagactcg ttgtggcaaa gacaacaaga aaaaataaaa tattcaattt
     7501 taaaaataaa agttgctctt tattttcctc tctcgtaact aataattttg agagaggttt
     7561 ttttttaaaa caatagtaag tcgtataggt ttgaggtaag taaatgaaat ataaaattaa
     7621 aaatgtgcat aaaacattgt ttattaagga aagatatcaa atattatctg aacgaaatga
     7681 taattcctta aataactttt cattaaataa ttggcgttct acaatgtcaa ttatttctga
     7741 aaaaactttt gaagaaatgt tgaaattaaa taattacaat aaaaaaatat tttctaacac
     7801 tgtgaactat gattataccg aggaacagat aagactatat tcagaatatg ccaaaaattc
     7861 ggaatggtat aaatttgcgg agggttcatt tgaaatattt agaaaacatc cccaaagaat
     7921 taattttaag aaagattttt ctagaatttt ggaacccttt attattaatt tgcttaaatt
     7981 aatcaataat tatctagaga ataaagaata cgagtggatt gacaagaatg gaaatatttt
     8041 ttcctctcta gtattttatt tagaagattt aatctatcct tggattgtta aacctttggt
     8101 tttagagata aattcattgc gtgaaaaagg tttacttgaa ggggaatcgg agcagcaacg
     8161 gtacaaatat tttataacat tgtttgacaa ggaagagaat atattaaatt tttataacaa
     8221 atatcccgtt ttactgaggc aaatatcgga gtcttgtctt cggttctata cttattttat
     8281 agaaatttta tcaaatttag aaaatgattt tagtgtgcta gaagaagaat tagggctaag
     8341 ggggaaatta aatgatataa aatttggaaa gggtgataca cacagccaag gaaaaactgt
     8401 tttgatactc ttctttgatg acgcgaaaat tgtttacaag cctaaaaatt taataatcaa
     8461 taactcacta aatactattg ctgagtatat ccgaaaggtt gatgaaaaaa ttaggataag
     8521 aatacctcga actattgctt attcggatca cagctatgaa gaatttattg attatctacc
     8581 tctagagcaa aagaaaaatt tacctgaata ttattataat tttggtgtgc ttttagcatt
     8641 tatatattta tttaatggga gtgatataca ttttgaaaat ttaatttcct atggagatat
     8701 gcctgtaata atagactttg aaacaatgtt acagcaacct ctatttgatg ataaaactgg
     8761 tcagagtttg ctggataccc tgtttcacag ggtgactcga actttgcttc ttccaacaga
     8821 gggagtaaaa agggaggatg gtcttgatgt tgagatgagt gctcttacag gaaattttaa
     8881 gaaggatgct tttaatggtc aagttttaat taatttaaat actgataagg taaagtttga
     8941 tattgggaaa attgattttg aaggtgggaa aaacctgcct gttcgggatg gtgatataga
     9001 atttgataag tatataaaag atttcaaaaa aggttttagg gatttttatc tgatatttga
     9061 agagttaaat aaaacagaag aatttaaaat gctattaaaa gcaaacttgt atggtttaaa
     9121 gacaagggta ctttttagag acacaaatag ctatgcttca gtactatctt ttttatatca
     9181 tcctgatttt tatgaagaaa tgttagatag agaaaaagca ttggaaaatc tctggagcaa
     9241 taagttttct aatcaaggta ttgtagcaag cgaatgtgaa caaatgaggt tattagatat
     9301 tccgattttt tatacagata caaatatcaa tgaaatctac gatgattttg gaaatcattt
     9361 tatttcccta catcaatttt ctggatatga ctattttatg aaatatttac ctaataataa
     9421 tttggaaaat ttagaaaagc aacttgatat cattgaaatt tattttccaa gctttgatca
     9481 gcgaaaaaaa ggatataaat taaacttatc taatagaaaa aaactcccaa atgaaagttt
     9541 agttactatt ctgcataatg aagtagaaaa tattgcagac tctttggtta ttaataatat
     9601 ttatgacgaa tatccaattt ggagtatacc tgttaatttt aaaggttcta aatggtgtct
     9661 tgaacaaacg ggtaatgata tgtatagggg tagagctgga atattactgt ttatgtacta
     9721 tgtaaaatta ttgaaagata aatcatcata tactcaactg tacaataaaa tgttatctgc
     9781 aattccgcca tctgtttctt tatctaagac cacatttggt ttaactgggg atataggata
     9841 tttcattgtt ctatccatta tagaggatta cgatacaaat actctcgcat gcttaaatta
     9901 tataaagagt gttttaactg agcttgaaaa gactgatttt gcaagtgttt caaacaagtc
     9961 tgactatatt aatggtcttc tacctttaat taatacactg gtaagatatt ataggagagg
    10021 aatagagaag gaacgtgttc taaggctagt attaagttta ggtgatacgc tatataatga
    10081 tgtaagcgag agagataata gtaattttgg atatagtttt ggccatggac tatcaggtgt
    10141 aatttttaca ttaaaaaata tttataaagt gacaagactt aaaaaatata aagaattaat
    10201 tttacaacta gttcctaggg agaaaatcaa aattcattct ttgaagtggt gtagtggaga
    10261 atttgggaca ttagttaatc atccccaaag tgttccagag ggaattgtag ctagtttaga
    10321 taatgataca ttttgccatg gaagtatggc cataataaat ttttacatcg actacatgaa
    10381 agaaatggat actagtatgg aattggagtc tttattgtgt agtgttgtaa tgaataaatc
    10441 aaaagaagga gagtatcgta tcgtccaaac aagcaatttc ccagattttt ctttgtatac
    10501 aggtgtgact ggtattgctt atactttttt aaggtatatc gcactgaatc agaatgacaa
    10561 aaagatagtt atcccctcat tacttgaaat ctagcttaat ttatagtttt gtttctaaaa
    10621 tagaggtgtc cactcattaa gcaatataaa aataccaaga ttgactagtt taatatgtaa
    10681 ttctataaaa tatttttaat agtgtagctt ttcgttgaga taataatata ataaagaaaa
    10741 gttctattct aattgctaaa cggcttgagg tatatgctac tgttatagaa atgattttaa
    10801 actaaaatca aaattactcc aaaaatagta ttgattttgg tttaatacaa aacatatgta
    10861 ataatgtgag tcaacaaaag tctgtttttg taccatacta tcttgaaaaa tctactaaat
    10921 tcaaattgag aggatgaatt aaaatgaata aaatatttat atatgcagga gtgcgaaatc
    10981 ataactctaa gactttagag tatactaaga gactttcaag tatcatttct agtagaaata
    11041 atgttgatat atctttcagg acacctttca attcagagct agaaatatct aattctgatt
    11101 cagaagagtt gtttaagaaa ggaattgata ggcaaagtaa tgctgatgat ggaggtgtta
    11161 taaaaaaaga gttattagag tctgatatta taattatctc ttctcctgta tatttacaaa
    11221 acgtatctgt ggacacaaaa aactttattg aaaggattgg ggggtggagc catctttttc
    11281 gattagctgg aaagtttgtt gtaacattag atgttgctga gagtaacggc tctgataatg
    11341 tgtcagaata tcttagagat atattttcat atatgggagg acagatatta caccaagttt
    11401 caattaccaa ttcactcaaa gatattgcag aggctcagtt gatggaggca acttataaaa
    11461 ttgaagatgt acttgaaggg aaaattaagt acaaaacaac ggattatcaa gaaagagctt
    11521 accagacatt aaaattaatt ttagaaaatt atgattccga acattttgag aagatgtatt
    11581 gggagaaaaa acgccttttt gaagctaata gtttagagga atggtattat gttgaaaata
    11641 ttaaataact ctgtcatata tttatgtttg attccgttat tgttcctatt attgataatt
    11701 tttccaaatg attcattaat ctattatttt cgattgattt taatttcgtt aatatcaatt
    11761 acattacatg aactaggtca ttttttagtg ggaagatgtt tatcttataa actagagatg
    11821 cttgctactc cctttttctt ctatttcaga aaaaaaatat atttcaaatt tccagtgtta
    11881 ttagcattcg gttattgtca aatgagtaat agaaacatta ctaatgaaaa aaatagtgat
    11941 aggaatttgg tgttctactt ctttggggga ggtggagcta acctaattgt cgcaatatta
    12001 gcacttttgg gatttgtgcc gtacgcatca gaatttttta ttttgaatat aattcttttt
    12061 ctagttacgg tatgtttacc aattgatgga acagatggca atgctattag agagatagtt
    12121 ttgtattcaa aagattcaaa aacatatcag agattctttg cgaacagtct ctataataat
    12181 ccttatataa caatcgacga ttttgcaaaa ttaacctcta aagaaaaatc ttttttttca
    12241 aaatttgaaa aatgtttgat aaacctttac tttgaagtga aaggtgaagg gtcagcattt
    12301 acaattgcta atcatgaagt ttttgattca aatattcagg aaaatattat ccatgagtac
    12361 tataaattac tacataaatc ttctgattgg attattccac agaacttatc tttagaagaa
    12421 gttgttttta ccttgtcaaa ctatatttac tcgaaaaata ataaatattt agaaaagatt
    12481 aagtatctaa agaaattagt agattttaga caagaagaaa ttatcgactt tattttgaac
    12541 aaggaggaag tattgtgaaa attccaatga tatatcaaat ggaaaattca gaatgtggat
    12601 tagcatgctg tgccatgata ttgaactatt ttaaatatga gatttcttta aatgaactac
    12661 gtgaaatcta cccatcatcc agatctggat attctctcct atctataagt aaagttttag
    12721 gagattttaa tataagttct catgctttta aagcttcggt aagagattta aaaccgctca
    12781 gtttcccact catttgcttc tgggagagtt ctcattttat tattcttgaa aaaattagta
    12841 aaaacaagtt ttatatttta gatcctgcaa aaggcaggca gagaatgtca ataagtgaat
    12901 ttgaaaggca ttattcaaat atcattttaa catttaaaaa gttagatagc tttatgtctc
    12961 gtaaagataa taagaagtcg cctgttttaa agtatttttt taagtatagg aataagctag
    13021 ggattttatt ttttgtaaca gcattattgt atgtaataca atcattagta cctatagcta
    13081 atagatacat aattgacacg aatttcaagg acgattcgta ttcgtctaga atgttattta
    13141 ctatattatt tatatttact gtttcattct cactaatgta tttattaaga cagatatatg
    13201 ttgcatcctt aaaatatata atggataaag agattagcta tgattttatg aaacatttga
    13261 tatatttacc ttacagtttt tatgaaaaac gtactttagg ggatatactt tttagagcta
    13321 actctattgt ttatataaga gaaatactat caaataattt tatagcagct atacttgatt
    13381 tgttaatgat tgtggtttat gctgtggttt tatttagctt ttctaagtac atggtaatct
    13441 ttttaatatc actaagtcta gctctatcta ttgtaatgta tccaatcata aaaatctcaa
    13501 aaaatttaat tgataaaaat ataaaagaaa aggttaatgt tcaaaatatt acttccgaag
    13561 taatttctaa aaatagtgat attaagctaa ctggagaaga ggaattttgg attaacaaat
    13621 gggataattt taatacaaaa cagctcatca taggtcgaaa acttgatata catttatcaa
    13681 ttgttagtag tataacgaat gttttacaaa ttattctccc tgttttgacc cttattgtag
    13741 gtgtaaatat aaaaacattc gaacaattga cgttaggaca aattgtagca ataagtacag
    13801 tctcaccata ctttatttct cctataattt ctttaagtga taactatata caattaatgt
    13861 tattaaaggg atatttttta agaatagagg atgtgtttaa tactaaatcc gaattaattc
    13921 cagaaagagt cagtcaagat ataaaatttg ataaaaaaat agaattaaaa gatatttggt
    13981 ataaatatgg attatttgat gattatgttt tgaaaggaat aaatgttact attaaaaaag
    14041 gagaaactgt tgctattgtt ggagaatcag gttcaggtaa gagtacatta gctaaaattt
    14101 tattaggttt attagaacct aatattggtt caatagaagt tgatggagta gaaaaagaag
    14161 aaattggtca aacattgtat agaaagattt ttggagcagt gttacaaaat tcaaccctaa
    14221 gttatggtac cttaagagag aatttgacat ttggacactt tgtttcagat gaagaattaa
    14281 tgacaaatct aaattcaatt ggtcttagca atgtagttaa atctttacct cttggattag
    14341 agacaatcat cgctgaagaa ggtaataact tttctggagg gcagcagcaa atgatacttt
    14401 tagctcgttg tcttttgtcg aaaccttcgg tagttgtttt ggacgaagca acaagtagtt
    14461 tagataattt atctcaacaa attacaactt cttacttaag tgaaatcggt accactaaga
    14521 ttttaattgc ccatcgacta gatactatca agtctgcaga taagatctta gtaatgcata
    14581 atggtgaaat tgtagagatt gggacccata gagaacttct tgaactagga ggcatttata
    14641 agcaattgta ttcaaataat tagtttttga ttaaaagggt aaatttatga agattatgaa
    14701 aaaaaaatat tggactttag cgatattatt cttttgtttg ttcaataatt ctgttactgc
    14761 tcaagaaata cctaaaaatc ttgatggcaa tataactcac actcagacta gcgaaagttt
    14821 ttctgaatct gatgaaaaac aggttgacta ttctaataaa aatcaagaag aagtagacca
    14881 aaataaattt cgtattcaaa tcgataagac agaattattt gtaacaacag ataaacattt
    14941 agaaaaaaac tgttgtaaat tggaacttga accacaaata aataacgata ttgttaactc
    15001 tgaaagtaat aatttactag gcgaagataa tttagataat aaaattaagg aaaatgtttc
    15061 tcatctagat aatagaggag gaaatataga gcatgacaaa gataacttag aatcgtcgat
    15121 tgtaagaaaa tatgaatggg atatagataa agttactggt ggaggcgaaa gttataaatt
    15181 atattctaaa agtaattcta aagtttcaat tgctatttta gattcaggag tcgatttaca
    15241 aaatactgga ttactgaaaa atctttcaaa tcactcaaaa aactatgtcc ccaataaagg
    15301 atatttagga aaagaggagg gagaggaagg aataatatca gatattcaag atagattagg
    15361 tcatggtacg gctgttgtag ctcaaattgt aggggatgac aatattaatg gagtaaatcc
    15421 tcacgttaat attaacgtct atagaatatt tggtaagtcg tcagctagtc cagattggat
    15481 tgtaaaagca atttttgatg ctgtagatga tggcaatgat attatcaatc ttagtactgg
    15541 acaatattta atgattgatg gagaatatga ggacggaaca aatgattttg aaacattttt
    15601 gaagtataaa aaggctattg attacgcgaa tcaaaaagga gtaattatag tagctgcatt
    15661 agggaatgac tccctaaatg tatcaaatca gtcagattta ttgaaactta ttagttcacg
    15721 caaaaaagta agaaaaccag gattagtagt tgatgttcca agttatttct catctacaat
    15781 ttcggtcgga ggcatagatc gcttaggtaa tttatcagat tttagcaata aaggggattc
    15841 tgatgcaata tatgcgcctg caggctcaac attatctctt tcagaattag gacttaataa
    15901 ctttattaat gcagaaaaat ataaagaaga ttggattttt tcggcaacac taggaggata
    15961 tacgtatctt tatggaaact catttgctgc tcctaaagtt tctggtgcga ttgcaatgat
    16021 tattgataaa tacaaattaa aagatcagcc ctataattat atgtttgtaa aaaaaattct
    16081 ggaagaaaca ttaccagtaa aaaatggtat aaaagtgtta aatataccaa acgtattgag
    16141 atatgatttg aatatgttac aattagaata taaaaatgaa caaagttggg atagtttcat
    16201 agataatgtt aatttaattg agttggaaga gagaattcaa actactattg gaattaaaca
    16261 aataaacaca cacaatatta ttactattgc ccgagaaggg tactctcaaa attatttacc
    16321 taacacttca gaaaatacat ataattcatt acaagtcagt ttagttggag tattactact
    16381 ttttataagt atggtaaata ttttatgggc taaaaaaagt aaatgaaaat aaaatttgga
    16441 gccctctgaa aaagtaagtc ctacagttca actaaaatga gtcaaaagat gaatcacctt
    16501 gatgtagggg agtttgtctt attgctgcct gaacacctcc gttcagagga agaacattat
    16561 aaatctgttt ttgaagacga cttaaccagt cgcatatcta gtcaagatga acgacagcaa
    16621 atgactgcta cggtaggtta tttagaatca ggtcaggatc gttttgtgta taatacgacc
    16681 cctatttctt accagcagtt tttgaaagat ccaatcatca ttgttataac accccaatca
    16741 actggtccac agtccatttt gttttggata gacgcagtac agaactacgt tctctttaat
    16801 caattgtctg atgcccagga gcttatccag agacaaggca ttgaaaattg ggtctcagaa
    16861 atgcaaacag gttaccacaa ctacatcaca ttattggata atatccagag ggaacgttgg
    16921 gtaatgctag caggagctgt gcttgggatt gcaacttcaa tcttgttgtt taacactatg
    16981 aataggctct actttgaaga atttagacgt gccattttta tcaaacgcat tgcaggtctc
    17041 aggttcttag aaatccatcg cacttatctc tttgctcaac tgggtgtgtt tttactggga
    17101 tttgttgcga gtgtatttct tcaggtagag ataggagttg ctttcttagt cttgttactc
    17161 tttactggtc tatctctttt acagttacat gtccaaatgc agaaagaaaa caagatgtcc
    17221 atgcttgttt tgaagggagg ttaatatgat tgaacttaaa caggtgagta aatcttttgg
    17281 agaacgagag ttattttcga atctttcaat gacatttgag gctggaaaag tctatgcctt
    17341 aattggttca agtggtagcg gaaaaacaac cttgatgaac atgattggga aattagaacc
    17401 ttatgatggg acgatttttt accgaggtaa agacttggcc aattataaat caagtgattt
    17461 tttccgtcac gaattgggct acctcttcca gaactttggc ttaattgaaa accaaagtat
    17521 tgaagaaaac cttaagctag gtctcattgg tcaaaagttg agtcggtcgg aacagcggtt
    17581 gaggcagaag caggctttag aacaggtcgg cctggtttat cttgacctag ataagcgcat
    17641 ctttgagtta tcgggcggag aatcgcaacg ggttgccttg gcaaaaatta tcttaaagaa
    17701 tccacccttt attctggcag atgagccaac agcttcaata gacccagcaa cctctcagtt
    17761 gattatggag attttgctat ctcttcgaga tgataatagg ctaatcatta tcgcaacaca
    17821 taatccggca atttgggaga tggctgatga agtgttcacg atggatcatc tgaaataaaa
    17881 atccttgttt ttaattgcac gatgagttac tgaaatatta tcatgaatca agaattggag
    17941 ttaatttaga attgtactta atttagaatt gtactttatt aatattgagg taactttttc
    18001 ttgataaagg aagaaataat ggagaggaag ttagaatgaa aaaattcgac aattatatta
    18061 ttgagaagcc ttgcgattct aattcagata aactgcaaaa aatcttaata attgaaagtt
    18121 tggtagatga tattttgcaa ttttctctca gaatcaataa tagtgtagga gagattttcc
    18181 tcctacaacc gttttaaaag aaaactatct ttattccatg ttattttgag gaagatattg
    18241 tgaaagtcaa agatgatgat aaagttgagt ggaatttgtt agaatttcaa aaatttagag
    18301 catttttggc ttagtaatct gtgttgaagg ctcaaaacct atggtaaaaa agtagctttg
    18361 aaaacgtatt gcctccaaag atttagttaa ataatgattt aacacaaaaa gaaattattg
    18421 aagttctgga aagatgttgt ttcagtattg agaaaaggtg ggaaaaactt gcgattttca
    18481 cagagaaagg aagaaaaagt atagaaatat agtcaattga aacaagaaca ggataaaaga
    18541 accttttgtg ccatattttt ctcctttcgc tttacaattg gattgaacac ctttattgta
    18601 tcgcgtttgg agtttttttg gtataacctt cgacgcacac ccgcatagcg ggtgtttttt
    18661 ttgtctcgca cctaacggag cgagacaaac taatagtcac ttaatcaaaa aacgcaccat
    18721 atcaaaaact aaaaagtttg atatcatgcg tcatgtctta aactaattga ctatactttc
    18781 tattcaaatg agcttttaac caattgattg agccaatcca ctcttaaaac caaagagcaa
    18841 tttctcgctt agctgactct tctgaatctg aaccatgtac aacattttgg ataatctcat
    18901 tttctccagc agcttttgca aaatcacctc gaatagtgcc tggtaaagct tcttctggac
    18961 gagttgcacc catcatggtc cgccaagttt cgattacttt gggaccagaa atgacaccca
    19021 caagaactgg acctgaagtc atgaattcac gaatcggtgg gtaaaaactc tgaccaacca
    19081 agtcctgata gtgctggtca atcaactctt ctgaaacctg tgaacgaaac tccaattttt
    19141 cgattgtaaa tccacgttgt tcgatgcgct ttaacacttc acccactagc cctcttttta
    19201 caccatctgg tttgatgata aagaatgttt gttccatacc cgtctccttt gtcagcttct
    19261 ttcttttatt ttaccacatt tcgtggaaaa atggagaaag ttttcagaag agagaatgag
    19321 agaaccctcg ggttctctca ttctctctta ttctactgtt tcttccacag tttcaacggc
    19381 agtatccaca actacttctg ttgtttcttc atttccttct tcctctactg gaggattaag
    19441 gtattcttct tcgttgacag catgtggttc aaggttacgg taacgggcca taccagtacc
    19501 agctgggatg atcttaccga tgataacatt ttctttaagt ccaaggagat ggtctttctt
    19561 accacggata gctgcgtcag taaggacacg agttgtttcc tggaaggaag ccgctgacaa
    19621 gaaactgttt gtttcaagtg aggctttggt aattcccata aggactgggc gacctgtcgc
    19681 tggaactcca cctgcgataa ggacatcttt gttggcatct gtaaagtcat tgatatccat
    19741 gagggtaccc atgagaagat ctgtatcacc tggatccatg acacggactt tacggatcat
    19801 ttgacgaacc attacctcga tgtgtttgtc accgatttct accccttggc tacggtaaac
    19861 tttttgtact tcaccgagaa ggtacgtttc aactgacaag acatcacgaa ctgcaaggag
    19921 acgttttggt tggatagaac cttctgtcag agcagcacca cgcgctactt ggcccccaac
    19981 ttcgacacgc atacgagctg taaatggaac gacatattca ccttcgccag tttcaccctt
    20041 aacaaagact ttcttggtac gagttgatgc atcttcttcg atagcagtaa cttgtccttt
    20101 aacctctgta ataaccgctt cccctttagg attgcgggct tcaaagattt cttggacacg
    20161 aggaagaccc tgagtgatat cggtatttga ggcaacccca cctgtgtgga aggtacgcat
    20221 tgtaagctgt gtaccaggtt ccccgataga ttgggcagcg attgtaccaa ctgcttcacc
    20281 aacttcaacc gcatcaccag tcgccaagtt gataccgtaa cagtgacggc agacaccgtg
    20341 acgagtgtta catgtaaata cagaacggat agtcacttct tccacaccag cattgacaat
    20401 ttcacgcgcc ttgtcttctg taatcaattc atttggacca ataatcactg caccagtttc
    20461 tggatgttta acagttttct tagtgtaacg accgttgaga cgctcttcga gagactcgat
    20521 catctctttt ccttctgcga tagaacggat caagagacca cggtcagttc cacagtcgtc
    20581 ctcacggatg ataacgtctt gggcaacgtc gaccaaacga cgagtcaagt aacctgagtc
    20641 ggctgtctta agggccgtat cggtcatacc tttacgagca ccgtgagttg agaagaacat
    20701 ttccaatacc gacaaacctt cgcggaagtt tgaaaggatt ggcaattcca tgatacgtcc
    20761 attcggagca gccatcagac cacgcatacc ggcaagctgt gagaagtttg agatgttacc
    20821 acgggctcca gagtccatca tcataacgat tgggttctta ggatcttggt tagcaatcaa
    20881 gcgtttctca agtttttcac gggcagcacg ccattcagct gtaacagcat tgtaacgctc
    20941 gtcgtctgtg atcataccac gacggaattg tttggtgatt tgttcgacac gtttgtgtga
    21001 ttcttcaatg atttcagcct tgtcatcaac gactgggata tcggcaatac ccactgtcaa
    21061 tcctgcaaga gttgagtggt ggtaaccgag gttcttcatg cggtcaagta gggcagaagt
    21121 ttctgtcgta cggaaacgtt tgaagatttc agcgatgata tttccaaggt ttttcttctt
    21181 gaatggaggg ttgagctcaa gattgctgat agcttccttg atatctccac caagtggcaa
    21241 gaagtattta gctggaacac cttctgtcaa gttggcattg tttggttctt gcaagtatgg
    21301 tagcccctct ggcatgatat cgttgaagag aattttacca actgttgtaa gcaagacctt
    21361 atgtctttgc tcttctgtcc aaggcttgtt gaggctgtct gttgcgatac caacacgtga
    21421 gtggaggtga acataaccat tgcggtaagc cataaccgct tcgtcacggt ctttgaagac
    21481 cattccttca ccttcgcgac cagcttcttc catggtcaag tagtagttac ccaaaaccat
    21541 gtcctgagat ggagtaacta ccggtttccc atctttcggg ttcaagatgt gctcagcagc
    21601 tagcatgagg atacgagctt ctgcttgtgc ttcttctgaa agtggtacgt ggatggccat
    21661 ttggtccccg tcaaagtcag cattgtaggc ttcacagaca agtgggtgca agcgaagagc
    21721 cttaccatca atcaagactg gctcgaaggc ttggataccc aaacggtgaa gggtcggtgc
    21781 gcggttcaaa agcactgggt gttctttaat cacttcttca aggatatccc agatacgctc
    21841 atctccgcgt tccaccaagc gtttagctgc tttgacgttt tgcacgatat cacgggcaac
    21901 gatttcacgc atgacaaatg gtttaaagag ttcaatcgcc atttcacgcg gcacaccaca
    21961 ttggtacatc ttaagagttg gaccaacggc gataactgaa cgtcctgaga agtcaacacg
    22021 tttaccgagc aagttttgac ggaagcgtcc ttgtttacct ttaagcatgt ggctcaatga
    22081 tttcaatgga cggctacctg gtcctgtgat tggacgacca cgacgaccat tgtcaatcaa
    22141 agcgtcaact gcttcttgaa gcatacgctt ctcattttga acgatgatac ctggtgcatt
    22201 taactcaagc aaacgagcca aacggttgtt acggttgata acacggcggt aaaggtcatt
    22261 caagtcagat gaggcaaaac ggccaccatc caactgcaac attggacgaa gatctggtgg
    22321 gataaccgga aggatgttaa gaatcatcca ttcaggtttg tttccagact tgtaaaaggc
    22381 atccaaaaca tccaaacgac ggatggcttt gacacgcttt tgtccagtag ctgttttcaa
    22441 ttcttctttg agttcagcaa tttctttttc aagatctact tgcttcaaaa ggtcttggat
    22501 ggcttccgca cccatcttgg caacaaatga accataacca tattcacgca agcgctctcg
    22561 gtattcgcgc tctgtcatga tagacttgtg ctcaagtggt gtatccttag gatcaatcac
    22621 cacataagcc gcaaagtaga taacttcctc gagggcacga gggctcatat caagggtcaa
    22681 gcccatacgg cttggaatcc ccttgaagta ccagatgtga gatacaggag ctttcaattc
    22741 gatatgtccc atacgctcac gacgaacttt cgtacgcgtt acttcaaccc cacagcggtc
    22801 acaaacaatt cctctgtaac gaatgcgttt gtacttacca caagcacatt cccagtcttt
    22861 tgtaggacca aagatcactt catcaaagag tccttcacgt tctggtttca aggtacgata
    22921 attgattgtt tcaggttttt tgacttctcc ataagaccat gaacggactt tacttggaga
    22981 agctagggtg atttgcatac ttttaaaacg atttacatca accactattt cttccctttc
    23041 tattctaagt gaactgctta ttcttgttca gcagcttctt ctgttgcttc cgcttttgtt
    23101 gctttctcag cttcttcagc ttcaaaggct gctttagcct cttgggctgc tttttcgcgg
    23161 gctttttcaa ggtcatctac gtggatgaca tcttcgtcca ttccttcatc caagtcgcga
    23221 agttccactt cttggtcatc ttcgtctagg acacgcatgt caagaccaag agattgcaat
    23281 tctttgacaa gaactcggaa ggattctgga acacctggtt ttggaattgg tttgcctttt
    23341 gtaatagctt cataggcttt caaacgtccg ttgatatcgt ccgacttgta agtcaagatt
    23401 tcttgaagga catttgacgc accgtaggct tcaagagccc aaacctccat ctcaccgaaa
    23461 cgttgtccac caaactgagc cttacctccg agtggttgtt gggtaacagt tgagtatggt
    23521 ccgactgaac gcgcgtgcaa tttatcatca accatgtggt ggagtttgat catgtacatg
    23581 actccgacag aaacacggtt atcaaacggt tcaccagtac gtccatcgta aaggatcgtt
    23641 ttggcatcgc tatccatacc tgcttcttta acagttgacc aaagatcttc agaacttgct
    23701 ccatcaaaga ctggtgtagc gatgtgaata ccaagagtac gagctgccat accaaggtga
    23761 agctccataa cctgaccgat attcatacgt gatggtaccc caagtgggtt caacatgatg
    23821 tcgactggag ttccgtctgg aaggtaaggc atgtcttcta caggaacgat acgagagaca
    23881 acccctttgt ttccgtgacg tccggccatt ttatctccga ccttaatctt acgtttttga
    23941 gcgatgtaaa cacgaaccaa catgttaaca cctgattgca actcatctcc atttacacgt
    24001 gtaaagatct taacatcacg aacgacacca tcggcaccgt gtggtacacg aagagaagta
    24061 tcacgcactt cacgagactt gtctccaaag atagcgtgca agagacgttc ttcagctgaa
    24121 agatctttct cacccttagg tgttacttta cctacaagaa tatcaccttc tttaacctca
    24181 gcaccaatac ggataatccc catttcgtca aggtctttga gggcatcttc accaacgttt
    24241 ggaatttcgc gagtgatttc ttcaggccca agctttgtat cgcgcgtttc tgattcgtat
    24301 tcttcaaggt gaacagatgt gtagacatcg tccttcacca agcgttcgct catgataacg
    24361 gcatcctcga agttgtaacc ttcccaagtc atgtaggcaa cgattgggtt ttgtccaagc
    24421 gccatttctc cattttccat agaaggtccg tcagcgatga aatcgccttt ttcaacgaca
    24481 tcaccaactt ttacgagagt gcgttggttg taagcagtac ctgagtttga acgacggaat
    24541 ttttggatgt ggtaaacatc caatgaacca tcttcacgac gaacttctac cttgtcagca
    24601 tctgcgtaag taactttacc atcatactga gcaatcacag ccgcaccaga atcgtgggct
    24661 gcttggtatt ccataccagt accaacgtaa ggtgcctgag gattaatcaa tggcacagcc
    24721 tgacgttgca tattggctcc catgagggca cggttggagt catcgttttc caagaaagga
    24781 atacatgctg tcgcaacggc aactacctgt tttggtgaaa cgtccatgta gtcaacaata
    24841 ttagctggat actcttggtt gaccccttgg tgacgtccca tgacaatctt ctcagcaaag
    24901 gttccatctt cattcagacg agagttagcc tgagctacag tatattcatc ttcttcatca
    24961 gctgtcaacc aaacaatttc gttcgtgaca acacctgttt cacggtcaac cttacggtat
    25021 ggtgtttgaa caaaaccata tttgttcaag tgtccataag atgacaagtt attgatcaaa
    25081 ccgatgttag gtccttcagg tgtctcgatt ggacacatac gaccatagtg agtgtagtgc
    25141 acgtcacgta cttcatatcc agcacggtca cgagtcaaac caccaggtcc taaggctgac
    25201 aaacggcgtt tgtgagacaa ctcagaaagc gggttgtgtt ggtccatgaa ctgtgacaac
    25261 tgtgatgaac caaagaattc tttaactgca gctgttacag gacggatatt gataatttgt
    25321 tgtggtgtca agacttcatt gtcctgaaca gacatacgtt cacggacatt acgttccata
    25381 cgagaaagtc ccaaacgtac ttggttggca agcaattcac caaccgcacg gatacgacga
    25441 tttccaaggt ggtcgatatc atctacacgg ccaagtcctt cagccaagtt gaggaagtag
    25501 ctcatctcag caaggatatc tgcaggagtc accgtacgaa ccttgtcatc tgggttagca
    25561 ttaccaatga tcgttacgac gcgatctgga tcagttggag caataacctt gaatttttga
    25621 agaacaacag gctcagtcac aacggctgca tcgtttggga tgtagacaat cttgttcaag
    25681 tcgccatcca aatggctttc aatgctttca atcacgctac gagtcataat cgtaccagct
    25741 tctaccaaga tttctccagt ttcagggtct accaatggct ctgcaatggt ttggttgagc
    25801 aaacgtgttt taacattgag ttttttattg attttgtaac gaccaactgc tgccaagtca
    25861 taacgacgtg ggtcaaagaa gcgagctaca agcaagctac gtgagctttc agccgtctta
    25921 ggctcacctg gacgaaggcg ttcgtaaatt tctttcaagg cttcgtctgt acgagagtcc
    25981 attggattct tgtggatatc tttttcaaca gtgttgcgaa ccaattcgct gtcaccaaag
    26041 atatcaaaga tttcatcatc acctgagaaa ccaagagcac gaaccaaggt tgtaaatgga
    26101 atcttacgag tacggtcgat acgagtgtag gtgatatctt ttgagtcgct ttcaagttcc
    26161 aaccaagctc cacggttagg gataacagtt gaaccatagc ccaccttacc atttttgtct
    26221 actttgtcgt taaagtaaac acctggtgag cggaccaact gagaaacgat aatacgttca
    26281 ccaccattga tgatgaaagt acccatttct gtcatgattg ggaaatcacc aaagaaaact
    26341 tcttgggtct tgatttcgct tgtttcttta ttgatcaaac ggaaggttac aaaaattggt
    26401 gctgagtagc tagcatcgtg gatacgagct tcttctagcg tatattttgg ttccttgatt
    26461 tcatatccaa caaattccaa ctccattgtg tctgtgaagt ttgaaattgg caatacatct
    26521 tcaaacactt ccttaagacc gtggtctagg aaagctttga atgagtcagt ttgaatttca
    26581 atcaaatttg gtaagtcaag aacttctttg attcttgaaa aactacgacg ggtacgatgt
    26641 ttcccgtatt gaacgtcatg tcctgccaag atgattctcc tttgtaaata agttccaagc
    26701 cttgtcaatc aggcttttct aatcgtcata tggttgtaaa ccccttatca ccgtgtcctc
    26761 ttgacgaatt ttcagaatct ttaagcctct gttacaaatg ctcaaaatct tgaaaaaaag
    26821 cacaaaaaga gcagctaaat ctgacttttt cagaagattt aactgctgtg agccttgtct
    26881 ggacaatatt tcagacaaaa cctacgacaa atgattaccc atattatacc ctatttagct
    26941 agatttttca aggggtttca gtaggttttt ggtaaatttt ttcccataga aaacttggca
    27001 tcacattcga atcacgctat ggtacaaaaa actgaaaaaa ctattgactg aaaatcattt
    27061 tcaaggtata ataataaacg ttaaggcggt atagccaagt ggtaaggcac ggctctgcaa
    27121 aagcttgatc gtcggttcaa atccgtctac cgccttctat aacttgattt atcaggtttc
    27181 aaatgaacag aaagcccaat ttgaagggct ttttttattt tccctcgaat aaatacgtat
    27241 aactttaaaa acttttggag cgagtttgtg gcagagttct ttccatggca taattccctt
    27301 ttgaaatcaa ttgaaaaaag cttcgtcacg cctggtgaca aaagcctcta gtttattctg
    27361 tttcttcttc tatttcgact tctgtgattt ggacttttac cttggtaaca cgtccattct
    27421 tcactttatc attggttaag ataaactgtt tgttttggct gaccaattca tagctgagtt
    27481 tctcagtcgt tggaatagtt cccactcctg tcaaataata accagcgata gtatcaacgt
    27541 catcactttc cagttcaaca tcaaagtaat tattgaaatc attgagggtc atagttcctt
    27601 gaacaatgta ggtatcctcg ccaatctgat gaacatctat tgctgctttg tccgtttcat
    27661 catcaatttc accaacaatt tcctctaaga ggtcttccaa agtcaccaaa ccagccatac
    27721 caccgtattc atccagcaag attgccattt gtctttgggt atttcgcagt tcttttagca
    27781 agtcatccac aaaaatagtt tcaggtacaa aaagtggatc ttgtaaaatt ctcttccaaa
    27841 caatattgtc aaaaccgtcc acaaagcctg ccttaaggag actcttggtg tgaatgattc
    27901 caattacatt gtccttatcc ccatcataaa ccgggatacg agaataattt tgttttaaaa
    27961 tactttggat aatggcttga ctatcatcct gaatatccac cataaaggca tccgttcgag
    28021 gaaccataac ctctcgtgcc atcagttcat cgagcgaaaa gacaccttgt agcatctcaa
    28081 tctcatcagc atccaatgtt tcttcactat ttgtcagcat ataggcaatt tcatcacggg
    28141 tcatcttttc atccgcatca tcgaatgaca taggagtcaa atggctcaag aaattggtcg
    28201 aagcagctaa aagccaaaca aaaggactga ctagttttcc gatcccaatg ataatcggcg
    28261 ctgtacgaat tgccaaggca tcctttagat taagagcgat tctcttagga tataattccc
    28321 caaaaacgat ggaaatatag gtcaaaaatg ccaaggatag aaaagttgcc acggcttgtg
    28381 ctgtttcgcc attcccaagc caagaggcaa tcacacgtcc tagagtatca gttaaactcg
    28441 cccctgataa gattgtaatc agggtgattc ctacctggat ggttgataaa aagtggttag
    28501 gattttctag taccttcagc aggcggatgt agcgtctgtc tccttcttcc gccttttgtt
    28561 caactcgggc acgattaaga gaaaccatgg ccatttctgt ggctgagaaa aaggcattta
    28621 ataccgtcaa gataaacaat aaaacaaatt gtagcaacaa attctgacta cttgggtctt
    28681 ccatagttct tctcctaaaa tagtatctta tcctttatta tatcacaaaa tttaatccaa
    28741 tacatattat tttttcttac cgtaacttct caaagtaact tccatctctc tcccaaaact
    28801 ggaagttagt tttagaagtt gctatttttt cttagtacct gttctagtcc tgcttaaact
    28861 agtaaaaaga actcctacat ccataagtga cataggagtt taggcttatc ttttactgag
    28921 ttacagttac ttctccagtt cggtaatcca gttgaagtcc cttttgaaca ttgggaacta
    28981 gaacattgaa ttccaattct ccatccgaag acttggcttc aatctgtgaa gctgagggaa
    29041 ctaaatcctc gtttgaagcg tagtaaaggg ttacacggta acggacacgc ttgttttggt
    29101 ccaaggcttt acgcaccttg ctttcatagt agttttgacc agtcgaatac tcggcttgtg
    29161 cctgatttgc ccaggctgtc tgaacagcaa tgtttttagg attgcttgtt gaggcatcaa
    29221 aaccatccaa accaccgatt aaggcatagc ctaacaaatg acctctatcg actgcatggg
    29281 tataagagcc ctttagattc ttgacctgat gccaacctgg aggagtccaa gaagttgaac
    29341 cattcccagt ttctttacga ttcttgtact gacgagtggc cttagacaag agggcattag
    29401 ctacggttgg aacagtttcc ttgcccactg tctttgtttt attgtcagcg tagggcttac
    29461 ttgaaacctt ggcatctaga tttgttttat taccattgac gataaaagca cctgagccat
    29521 tccactccag actccccttt atttgactct tgactgcgtc tgttaagaca ctctctgcca
    29581 atgcttgact aggagcttca gacgcttgtt ttttctgact aagattggtt ttgggactat
    29641 taggtgccga cggcatctgc ttgatataat agctccctgt agacaaaagc aataacacta
    29701 gcagtccgat tagtgtctgt cttgtttttt tgttcatatt tctccttatc tttagaaaaa
    29761 ggctggttct ccagcctaat ttcctgtaaa tttatgaatc aattcctgcc attttgctgg
    29821 agacaggata gcccatggat cttgaccctt gcccaagatt ccataaccta ccattaaacc
    29881 gattcctaga gccagagtac ctaaaatcag tactatgatg actaaaagta aacgcttgac
    29941 tacgtagctt gatttcttat tcatcttcat cacttgcctc aatccgctga atcttagcac
    30001 ctagctgcgc caacttctca tggaaaccgt agtaacctct atccaagtga accaatttac
    30061 cgaccacagt ttctccctgt gctaccaaac ctgtcaaaat caaggccgca ctggcacgaa
    30121 ggtcagttga aagaacttct gctccctgca aaggctgtcc accaacaata cgagctgtat
    30181 cacggataat ctcagaatgc aagcccatgc ggcgcatctc ttctaggtgt tggaaacgat
    30241 tttcgaaaac tgtctccacc atggttgatt cgccttttgc aactgtcatc aaggctgtaa
    30301 attgagcctg catatctgtt ggaaatcctg ggtggggcaa ggttttcaca tgaacagctt
    30361 ttagattttc tagttgagaa cgaacacgaa ttccttcgtc ttcttcaatt acttcaacac
    30421 ccatttcaag taacttggca atcaagggac ggttgtgctc ccagacagcg tctcgaatca
    30481 agacatcacc accagtcatg gcagcagcta ccataaaggt tcctgcttcg atacggtctt
    30541 ggactacatt gtgagtcgta ccatgaagtt tctcaacacc agtaatggtt atagtctctg
    30601 taccagcacc tttgaccttg gctcccattt cattaaggag aatggctaag tcaacaatct
    30661 caggctcacg cgcagcattc tcaatcactg tcaccccatc agccagagtc gctgccatca
    30721 tcaagttctg cgttgcacca acacttggaa agtccatata gatatgagca ccatgcaagc
    30781 gttctgcctt ggcttcgatg taaccagctg tctgactaat cttaaccccc atagcttcca
    30841 gacctttcaa atgaagatca ataggacggc taccaatcgt acaaccacct ggcatggata
    30901 ccttggcatg acccacacgg gcaaggattg gccctaatac aacgatggag gcgcgcatct
    30961 tgctgacata cttgtaaggg gcttcctcag tgatgtcgcc agtagcatcc accttgacaa
    31021 gatgagcttc ctcatcaaag tcaaccttgg cattcaaacc accaactacc tgattcataa
    31081 taaagacatc cgacaaaatc ggaacattct gcaagacggt ctttccttca cttgctagaa
    31141 tagtcgctgc caacaagggt aagactgcat tttttgctcc ctcgatcgtc acgcttccta
    31201 ccagacgatt atcgccacct tgaaccacaa ttttatccat actcgtttcc tttactcttg
    31261 atttcataat aatcctctaa gcgcttcttg ccacaaatga tacaggctaa taaagaaaga
    31321 actcaggatg tagcctatga caatgctaaa aaaggctact aataaacgaa cttttcttgt
    31381 attatcatct gtcactttta aaaccttctc ccatctaaca agatccttta aaaggtaaaa
    31441 actcacataa ataaagaaca tatgactact tagagtgaat aataattgaa ccatttgact
    31501 attataccat cttctctgtt tgtgcgctag tttggaaact tcactcaaaa attagggatt
    31561 gtttttcaag taatcaatcg catcttgtag ggttttaacg ggcacgattt tcatatccgt
    31621 cttgattgtt ttagccgctt ctagggctgt ttggtagttg tttttcgcgt ccggatgcgc
    31681 cttttgttct tcttcgctaa cagggttatc aggagcaaag aaaatagcag cacctgccct
    31741 agccgaagct acaaccttct tatcaatacc tccaatgtct cccacattac catcgcggtc
    31801 aatggtacct gtaccggcaa caatacgacc attacgaaga tctgggtgag ctatttgagt
    31861 atagatagct agactaaaca tgagaccagc acttggaccg ccaataccag ctgttgaaaa
    31921 gctaattggg acattgctga ttacctctgt acggtcaatc aagccgattc caattccatt
    31981 tttgccattt tccaaggtga tgatttttcc ttctgcagac ttggtttgcc catcctcttc
    32041 ataggtgacc ttgacggaat cccctaattt ttgagaactg acgtaatcaa tcaagtcttt
    32101 ggaactatca aaggtctgat cattgactgc tgtgactgta tcagagatat tgagaatccc
    32161 tttaaaggtt gaattatccg tcacattcaa aacataaact ccaaagtact tgagttcgat
    32221 atccttacca gctgttttta gtccttgata cttggccata ttttgcgatg tttgcatgta
    32281 gaattgattg attcgcataa attcaacatc ggaagaacca cctgtagtct cctgagcact
    32341 acgaatatct gtaaaaggtg tcaaccaagc ataaatcata tgagctaaag tggcatgttg
    32401 aacaccaacc gtaacgaatt gataggcacc agcttcctta tcttctgtgt catttacttt
    32461 aaggacttgg cgaatatctt ccgaaccacc tggaacctct atataataag gcaagggcac
    32521 tacaaatgcc aagaaagtca caatcaaggc cgcaatgacg tataagggcc atctaatctt
    32581 ttttttcatt tcttatttcc tccaaaatac tctcgggaac atagcaggca atatcctgac
    32641 caaacttcaa aagctctcta acgcctgatg aactgatata gagatgttca ggtcgactat
    32701 gtaaataaat agtctctata tcagaagaca gctgatgatt gtagtaatca aaactggctt
    32761 catattgcaa atccgacgca tttctcaaac ctcgcactag gcaagtagcc cccagtcttt
    32821 ttgcgacatc gaccaccaat ttatcatgag aagacacgac tttaacattt cccaaatgtt
    32881 tcacagcctt ttctaacccc cgtttacgat tttcaagagg gagaaatcct tgtttgtggg
    32941 gattaaaaaa aatacccaca taaagcttat caaaaagtct gctcgcccgt tcaatgatat
    33001 ccagatgccc atttgtcatc ggatcaaatg agcctgtgaa taagccaatc ttatctgaca
    33061 tagactgtca ccttactaat tccataaatc ttttccttcc agatacccag acaggcaatt
    33121 tcttctggaa gttcaacggc tttatccgtc tcgcacacaa ccataacatc ttcagaaaaa
    33181 agctctctct cagccatttt ttcaatatct gctacgattt gttccttggc atagggaggg
    33241 tctaagaaaa cgaggtcaaa ttccccagat acctgttcca atgccctttc tgcatccatc
    33301 ttgaggagtt gaaattttcc aacttccttg gtcatctgga tattttcagc cacgatggtc
    33361 tgagccttac ggtctcgctc caccaaaaca gcactggaca tgccacgcga tactgcttcg
    33421 atagataaac caccactacc tgcataaagg tccaagactc gtcccacttc aaagtaggga
    33481 ccaatcatgt taaaaatggc tcccctaacc ttatccgaag taggtcttgt cgtcttgcct
    33541 tctagtgtct tgaggggacg tcccccatag attcctgata cgattttcat actgtttatt
    33601 ataccaaatt atagacaaaa agagaaagaa aaccgaacct tgcggttcga ttctctacaa
    33661 aatattttcg taagtatcgc ggacttcttg aggccaaaca cttgtttgca cttctccgat
    33721 gtgtctcttg cgaagtagga acatggccat acgagattgt ccaattcctc caccgattgt
    33781 caatgggaat agaccattca acaaagactt gtgccattcc aattccaagc ggtcttcatc
    33841 acctgtaatt tccacctgac gtctaagagt ttcttcatct acacgaattc ccatagaaga
    33901 caactcaaag gctccaccta aagactcatt ccagacaaga atatcaccat ttagaccctt
    33961 gtagccattc tcagactcgc ttgtccagtc atcatagtct ggtgcacgtc catcgtgcgg
    34021 tttaccatct ggcaactcgc caccgatacc aatcaaaaag acggctccaa attctttaca
    34081 aatcgcattt tcacgttctt tcggtgtcaa gtctgggtag cgttctacca attcttctgt
    34141 atggataaag gtaatttgtt ttggcaagat agactcgatg tcatagcggg cttcaacagc
    34201 tagctcagtc aggcgaatag ccttataaat cttctcaact gtttctttta gataaacgat
    34261 gttacgctta ccatttggga taaccttctc ccagtcccac tggtcaacat aaacagagtg
    34321 ggttgcatcc aaggaatcct catctggacg aagggctttc atgtggacaa agagaccctc
    34381 tccttcacca aagccaaaac gagccaaggt gtggcgtttc catttagcaa gtgagtgcac
    34441 cacttcataa gtagcatcag ggatttggag aaccttgacc gatactggat tttccacacc
    34501 agacaggttg tcctgcattc cgtcaccgac cttactcaag ataggacctt gaacttcgac
    34561 aacttctagc ttatctttca aatactgggt aaaagtgttt ttgacaaagg aaatttcttc
    34621 ttgttgatgg ataaaacttt tcttcataga caactcctca aaaatttaat aaacgtatta
    34681 tacacctatt tccaagaaaa gaaaagagaa aatttaaaaa aaatcagtgt cactcaaaac
    34741 actgatttca tagacctttt agtcattgcg accaaagata cgtagaatac ttaggaaaag
    34801 attgataaaa tcaagataga tgctgagagc cattgacacc acccagcctg tcgctacacg
    34861 accttgtgat tgttcatagg cgaggcgaat cttttggtta tcccaagcaa tcaaccctga
    34921 aaaaaccaaa accatggcta cgctaatcat ataatcaaag aagccactag ccaagaaaat
    34981 attgactacc atagcaatca gtaaaccaat gagagctgcc atcattgctc gaccaatccc
    35041 actcaagtct ttcttggtaa agataccaac tgccgccatg acaaagaaga gaagggcgct
    35101 cgatacaaag gcagataaaa ctgtacccgg agtatagaaa gccaccacaa aactaagggt
    35161 aaagccgttt aaaacggagt aaagtaaaaa tactggaaga gcagctggac tatttcttga
    35221 agccatgcta ctggcaacga aaaccaaagc caactccgca aaagtagcaa tggtcaacca
    35281 gagacgcccc tgcatcaaca agtaaaccaa ctgagactga aagaccgtca acataaggcc
    35341 tgataccaaa gcagatagtc cgattcccag accaacaaag gcataaacct tagcgtaaaa
    35401 ttgattgaga cctgcacggt catgtataat agtgtgattc atccatttct ccttttctgt
    35461 gaacatcttt ccttgattat aacaaaaaaa gttaaaatta gcttaaatgg aagattaaaa
    35521 taccggctgc aaccgcaaca ttcaaactct cggcctgccc cttcatgcta atatggacca
    35581 actggtctgc actttcagcc ataaggggac taattccttg accctcattt cccataacta
    35641 gtacaaaatt ttctatagaa ggcagttctc tgtaatcaac agaatcttta gatagggttg
    35701 ttgctaacac tgggatagct acctttttag tttcgtcaag aagcgcttga ctagtcatcc
    35761 ggtaaatggg cagatggaaa tgactacctt gcatggaacg tagggttttg agactgtaga
    35821 tgtctgccga cttatctgaa acaatcactt ctgtaaaacc tgctgcatcc gcagttcgaa
    35881 tgatagttcc tacattacca ggatcttgca catcttccaa aaacaagaac ttgccctgac
    35941 tcaaatcagc ttgtcctact tcttcttttt gaaccacggc cacaattccc tgtggagtct
    36001 gagaatccgc caaatctagc aaaatatcct ctgacaccca gacagtttgc gaaaaagttg
    36061 ctaactgatc tcgataattt tctagggtaa agattttctc aatcgtcact ccagcttgaa
    36121 cagcttcttc aaacaagtgc cagccttcaa tcaaataggc tgacttgcgg tatttttttt
    36181 ggtgtaattt cttggtattt tttaccacag aattggcttt tgaggttata atagtcatag
    36241 aaatattata acacaatcaa aggggtttgg tatgcaaaag gttagaatga ttgcccaagg
    36301 tagggtgcag ggagtcggct ttcgttgggg tgtttatagc ctggcccttg aaatcggtgg
    36361 catcacaggt cgggtatgga ataacgacga tggcacagtg gaaatcttag cccaagcaga
    36421 ctcatcagct attatggcaa aatttatcca agaaatccga aaaggaccga cacctttttc
    36481 aaaagtcagt tacttagatg tcaaactgag caactttcct ccctaccctg actttaaaat
    36541 cgcaaattag gtctccagaa ctattgtata ttttgtaaaa aaacagtaga atagaaaggt
    36601 ataattttta aagaaggaat aaaaacagtg aaatctatta aacgttttgc actctcggct
    36661 atgggagtgg ctatgttgct tgtcttgact ggctgtgtca atgtcgataa aaccacaggt
    36721 cagccaacag gatttatttg gaatacgatc ggagcgccta tggctgaagc catcaagtac
    36781 ttcgctactg ataaaggtct aggctttggt gtcgctatca ttatcgtaac cattatcgta
    36841 cgcttgatta tcttaccact tggtatctac caatcatgga aggcaacgct tcactctgaa
    36901 aagatgaacg ccctcaagca cgtccttgag ccacaccaaa cgcgtctcaa agaagcgact
    36961 actcaagaag aaaaactcga agcccaacaa gctctctttg ctgctcaaaa agagcacggt
    37021 atcagcatgt ttggcggtgt aggatgtttc cctatcctcc ttcaaatgcc tttcttctct
    37081 gctatctact ttgctgccca acatactgaa ggggttgctc aagcaagcta cctaggcatt
    37141 cctctaggtt ctccaagtat gattttggtt gcctgtgctg gtgtccttta ctatcttcaa
    37201 tcgctccttt cacttcacgg agtagaagat gaaatgcaaa gagaacaaat caagaaaatg
    37261 atttacatga gcccactcat gatcgtcgtc ttctccctct tctcaccagc tagtgtcaca
    37321 ctttactggg ttgtcggtgg tttcatgatg attctccaac agtttatcgt caactatatc
    37381 gttcgtccaa aacttcgcaa aaaagtccgt gaagaactag ccaagaaccc accaaaagca
    37441 agtgctttct ctaaaccaag tggacgaaaa gacgttaccc ctgaacaacc aactgctatc
    37501 acaagcaaga aaaaacacaa aaatcgcaac gctggaaaac aacgttcgag ataagaagaa
    37561 aaaggcttag ctgatttgct aagtcttttt gcaagtcaaa agcccgatgt ttccatcagg
    37621 cttcttttct atccatgtac acgtttcata taatcttgat aactttcggt atccatgagt
    37681 tgtttagcgt tcttgacgcg atctgctgtt ggtggtttga ctccttcgag ggaatatgga
    37741 attccaagtt cacgccactt gaactcaccc atggtgtgat aaggtagaat ttcaaactta
    37801 tcaacatttt tgagggtctt gacgaactta ccaagttcaa tcaagtcatc atctctgtct
    37861 gtcaatcctg gaactagcac gtggcgaatc cagacaggtt ttccaatatc tgatagatac
    37921 tgggcacaag ccaagatatt tttattggtt tggctagtga caatcttgtg ctgttcttcg
    37981 ttgatttcct tgatatccaa aagaaccaag tcagtgacag ccatgagttt gtcaaacttc
    38041 tcaaggtaac gtggtttatt acggaaagga agagcacagg tgtccaaggt acagtggatt
    38101 ccttgttcct tagccttggt gaagagagca atcaggaaat caatctgcaa gagagcttct
    38161 cctccactga ctgtaatccc acccttattt ccccagaaac cacggtagcg caaggcctct
    38221 gtcaagacat catctaccgt ccgttcacgt gacttattgg actccatagc ccaagtgtct
    38281 gggttgtggc aatactggca acgcatgtga cagccctgca aaaagacaat aaagcgaata
    38341 ccaggcccat ctactgaccc aaagctttct gtcgaatgca ccattcctgt cacttgtcca
    38401 taatcaattg tttcttcaga catatcgtta ccttccttga aaacgtttta tagttttatt
    38461 atatcacgac ttgaaggaaa aacaagattt ttgcctattt tttagaaagc aatctgtttt
    38521 tcaatttcat tttcaatcta ttatcagatt attcttcaaa atcgaagcca tataaggttg
    38581 caaaatagtc ctcagggcgc tctgcacggc ggatttgacg ggctttacct tcttcggtat
    38641 agaggatttc cgcagaacgt aatttggcat tatactggta gcccattgaa aatccgtggg
    38701 cacctgtatc atgaatgacc agcaaatcac cgatttctgt atgaggcagt tcgcgattaa
    38761 ctgcaaattt atcattgttt tcacagagtg aaccgaccac atctaccact tcagctggtc
    38821 catctggatg ggtcacgttg ctaatatgat ggtaagctcc gtacatagct ggacgcatga
    38881 ggttgactgc tgaggcatcc acacctagat aggtacggta ggtttccttc ttatgagtga
    38941 ctcttgtgac tagagcaccg tgaggtgcca gcataaaacg acccaattcg gtgaaaatct
    39001 tgacctgacc aagacctgct gacgtaagaa cctcttcata caccttacga actccctcac
    39061 caatcaaggc gatatcgttc ggctcctggt ctggatgata attaacacca ataccgccag
    39121 aaagattgat aaagtctagc gaaatgccca acttttcctt gatttcaaca gccagttcaa
    39181 agagctgacg agccaactct ggataataga gatgggtcac ggtattggac gctaggaagg
    39241 agtgaatccc aaaagtcttg gctccttttt ccttcaagat agcaaaggct tcaaagagct
    39301 ggtccttggt catgccaaac ttagcctccc caggattgtc cataatgtct gtccccagtt
    39361 caaaaacgcc tccaggatta taacgacaag agatgatttc tggaatgcct gctactctct
    39421 ccagatgttc aatatcttca aaggcatcca agttaatggt cgcacccaat tcacgtgcat
    39481 aggcgtattc cttgtctggc gtgttgttgg aagagaacat aatctcagaa cccagaaagt
    39541 ccagtttatg gctcatcaaa agctctacat aactagagca gtccacacca caaccttctt
    39601 cttggagaat tttcaaaata gctggagttg gagtagcctt aactgcaaaa tattccttaa
    39661 agcccttgtt ccacgaaaaa gcttggttga cggctcttgc cttctcacga atccccttct
    39721 catcatacaa gtgaaaggga gtcgggaact cggcaacaat cgcttctaac tcttctctat
    39781 tgataaatgg tgttttcata agcttccttc tattctgttt gcaaagaaag gctgggacaa
    39841 tcgttccaac ctttagttct atctcttatt tatcttcgtc aaagatattg ccaacctcaa
    39901 catcgatggc ttggttcttg acatcaatat tggttacctt caagagtgac ttgtagtcaa
    39961 actgcttttc acgttcttct tgggcattgt ccgcaaagac cgctacacct gccagttctg
    40021 agtcgaactc gcgcaagaga ctaatcatac cattgaccgt tccgccacct ttcaagaagt
    40081 catccacaat caagacacgg ctgcctgcct taagactacg ttttgaaagg aacattttct
    40141 cgatacggtc accacttgaa cctgaaacat agttgacgct aacagttgaa ccttcggtaa
    40201 ttttcaggtc acggcgcaca atgacaaaag agacattgag gacattggca actgcatttg
    40261 caagtggcac acccttagtt gctacggtca taaccgcgtc aattttttgg tccataaagc
    40321 ttttggcaat aatacgacca atatttttca agatggctgg tgtgctaagc aaatcagaca
    40381 gatagatata accacctggc aagatacggt cactttctga caacttggta cgcaagtctt
    40441 caaccatttc cttagcatcc tgactcgaaa tagacggtgt gaagatgaca cctccgccag
    40501 ccccagtcac tgtctggata tgaccgattt caatttcctc aaaggcgcgt ttgataatga
    40561 cgatatcttc tgagatggat gatttagcag actcatactt ttcagcaaaa gtattgagac
    40621 tagttagttt ataaggatta ttaatcaaat agttggaaat gacaaccatc cgatcacttc
    40681 ttcttaattt catttctatt tcctattcca tttttattca aaaaatcaaa aagcaaacta
    40741 gaaagctggt cgctggtggt tcaaaacact gttttgagat tgtcaataga actgacaaac
    40801 cctgtaatat acctgcatat atacatacga caaggcgata ctaccctagt ttgaagagat
    40861 tttcgaagag tattcatttt tgtcttttac ttattatacc atattcacat aaaaaaacga
    40921 acattcttat cctaaaaaat gctcattttt cttaaattat taatctaaat ctggtttata
    40981 gaaggaacga ttatccatag cgaagatttt attggtcatc tctcctttat ccaccaaagc
    41041 aagagctgtt gacatcatca tcatgcttgc atccagattg tcaatcatat ggataatctc
    41101 tgcttccata atgcgtggac ggactgggct tccatactca agcaagccgt ggtgactgag
    41161 gatgacatga cgaagcaaaa cgacttcttc cttggtatca tcgatgccga gttccataac
    41221 tgtcttggta atttcgctat caatgagagc gatatgtcca agaagattac ctcgcactgt
    41281 gtactctgtc tggtctggcc ccgtcaactc gatgacctta gctaagtcat gcaacataat
    41341 ccccgcatag agcaggctct tattgagctg aggataaact tcgctaatag cgtctgccaa
    41401 acgcaccatg gtcgccgtat gataggccaa gcccgtttca aaggcatggt ggttggtctt
    41461 ggcagctgga taggagtaga attccttatc atacttggtg tagagatttc ggacaatccg
    41521 ttgccagaca ggattttcaa ttttgaaaat catttgcgac atgtagtcac gaatttcctt
    41581 gacatcaact ggtgacttga ccttgaaatc agctgggtca ttgggttcac cagcttgagg
    41641 caggcggaga gtaatttgat tgacttgagg ggtattgtta taaacttctc ggcgtccttt
    41701 catgtggaca accttacctg cggtaaaggc ctcaatgtta tgaggttggg catcccagag
    41761 cttcccatca atctcgccac tatcatcttg gaaggtaaag gctaggtagt ttttcccagc
    41821 tcgagtttgc ctcaggtcag ctgatttgat taggtaaaag ccttcaaata actcatcttt
    41881 tttcatgtga ctaatcttca tattcttcct cattttcttg aaaatggagt agatcaagcg
    41941 caggctcacc ttctgacaac tcaatgtgac ggagcgtccg ctcgatagct atggtacgac
    42001 ggtttaataa ttcatcaata ttgccagagg catgttggag atgtttttgt gccttgacca
    42061 gaataccacc aaacttgcca aactcggtct tgacactggc aagagtcttg ctgatatgat
    42121 cggcactctt ttggatatta agggtcttga aaccaactga tagggagtta agaagggctg
    42181 atagggtact tggtcctgca acaataatct gttcttcccg tctcaaatca tcaaagaaga
    42241 ccggattgcg gacgatttct gagtagagac cttctgtcgg aacaaacaaa actccaaaat
    42301 tggtcgtccg aggtggtgct atgtacttgt tcctaatatc cctagcaaag cgcttgacgc
    42361 ttgctaggag tgacttacga cagcgttcaa tctcatcctt gtcacctgtc tcataggctt
    42421 cttccaagcg gtaataatct gccagtggaa acttagagtc aattggcaga tagacgtatt
    42481 cttggtcgcc ttgtccgggt aacttgatgg catactccac tcgttcacta gagttttcaa
    42541 ccgttgcgta ttctcgttcg tactgggcag gtgtcatgat gtcttcaata atttgcccca
    42601 gttgcaattc tcccagaatc cctcgcgtct tggttccaga gagaaccttg ttaagagctc
    42661 cgacatcacg ggcaactgtc tgcatttctc caaggccacg attgacagac tccagttgtt
    42721 tagaaactgt ctcaaaggaa gcctgtaagc gtgtctgcaa ggtcttttct agtttttcct
    42781 cgaccgtctg gcgcatttgt tccaaacgtt gctcatttga ttcctgcaag gcttggagac
    42841 gttggtctgt cttgtctcta gtttggagga gattatctgt catttcttga cggacttggg
    42901 tcagaccttg gtgcaattca atccgcactt cttgcaaacg gtcgctgaca accacttcca
    42961 aatctttttg gtctaactgg ctggcttgtc tggcttggtc aaagcggtaa tccaactggt
    43021 ctgacaaatg atctgcctga tcctccaagc tcttacttaa gtgtttctcc tgcctatcct
    43081 gcctttgcca aatcagaaag agaccagcta gattggcaat taataataga ataagtaaac
    43141 tttccatcct acctcctgtc cttgctatgc agtacgacca cataaccatc tgggcaagtt
    43201 accgacactt ccctatctat atattcgtta gaagcgtaca cttttttaaa gaaaaaattt
    43261 tcctctgtca actcatactt ggctccaaga atagtcagct ggctatcccg aactggcata
    43321 aaggctagat agtcgtagtc tgaacgaggt tctagctgac tgattccttc tggacaataa
    43381 gtaatcaagt tttgcccatc ctcaatttct atttgatgca tatagggtgc caacttagga
    43441 ttgctaggca gaaagacatt ggccaacata tggtcaatac ggccacccaa ggcaccgaaa
    43501 atagtgacct gagcctgagg attttgttca aagatggtta agagagccaa ttccagatct
    43561 gtatcatcct tttctggtcg tgcttggaca aaatactggg cacctttttg aatcacctgt
    43621 cgctcttctt ccgtcacaga atcaaaatct ccgactgcta gagcaagagg taagtcttct
    43681 tccaagaccc agagcgagcc tcgatccacc ccaacaaaag catcaaaatc tgtccgataa
    43741 tgaccgcggt ttccgcctgc aaaaactgca accctagtcc agttgttttc tgagagtttg
    43801 tactcgctca ttgacttctc ccttaaagac ataggaacct gctacaaaaa cagtcgcacc
    43861 ggcttctttg gcttgagcaa tagtttggtc atcaatccca ccatccactt cgatttcaaa
    43921 gttcaaacct ttttcctcac gaagagcaac caactcacgg accttatcca tggtttctgg
    43981 cagaaaggct tgcccaccaa aacctggatt aaccgtcatg actaaaactt ggtcaactag
    44041 atgaaggacg tgcttgatgg cttcaactga tgtgccagga ttgataacga ctgaaggctt
    44101 aactccgagt gaacgaattt tttggagggc gccatgaata tgaggcgttg cttctacatg
    44161 gatactgatg atgtctgcac ctgcacgcgc aaaatcttcc agatgatgct cagggtttga
    44221 caccatcaag tggcaatcga aaaccatctt actatgagga cgaaggctct cgaccacacc
    44281 tgcaccaaaa ctgatttgcg gtacaaaatg actgtccatg atatcgatat gggcatattc
    44341 tgccccagtt gcttctagac gtttgatttc acgttcaaag ttggcataat ctgctgccag
    44401 aattgacgga gcaatcttgt attgagacat aggtttctcc ttattttgga atttttttgc
    44461 tgactttttt ataggtttct ctacgatttt caatttcact aaggaattgc aggtaattgt
    44521 caaaacggaa ggttgcaata acaccctctt caacagctgg tttgacggca caagacggct
    44581 catgggtatg ggtacaagta cggaacttac aatctcggct aacagtagca atctctggga
    44641 aagcctgatt gaggtcttca gcccttgata cttcatagtc caaggatgaa aatcctggtg
    44701 tatctgcgat tttacccccg ttgagattgt aaaaactaac agctcgagtg gtatggcgac
    44761 cgcgacctag actgtctgaa atttctcccg tttcaagatt gaggtctggt gcgattttat
    44821 tgagaagagt tgacttccca acacctgtct gccccataaa gaccgtaacc ttgcctgtta
    44881 acaaagacag gagttcctct ttactggtca caaagtcata gccgatgtca ccataggtct
    44941 gctggtaaaa atccagttct cccctatctt ccaacaaatc cattttggaa atatagacaa
    45001 tgggatggat gcccttgtgc tccaaaagaa ccaagaaacg atccagcaaa ttgctgttaa
    45061 aatcaggttc cttgacggac atgattacta cagcttgatc gatattgaca ataggcggac
    45121 gaaccagact gtttttccgt tcgtgaattt tgaggatata gccttctgaa ttttcctcgg
    45181 cagagaaatc tacccagtcc ccaacataag gggtatggcc ttttttacgg aaattcccac
    45241 gcgcgcgtgt ttgataaacc tggccatcac tctccacata gtagaaacct gccaaggctt
    45301 taatgatttg tccctgcatc ttagagtcct tgccctttaa gtgcgtctgc tagaccggca
    45361 aattctgcca agctgagagc ttccccacgc acacttggtg acaagcctgc ctggtccaaa
    45421 gccttggtca gcttgtcctt gacctcttca gtcttaccaa agtaacctgt caagttattc
    45481 cacaaggtct tgcggcgatg ggtaaaacta gccttggaaa ccttaaagaa aaagttctca
    45541 tcttctactg ctacggctgg ctctggacga cgcaccattt tcaagatggc tgaatccaca
    45601 tttggcgctg gcacaaagac cgtacgaggc acgataaagg caaccttggc tgtcatgtaa
    45661 tactgcacgg cgatagacaa gctaccgtaa gccttggtgt taggctgggc tgaaatgcgg
    45721 tccgctactt ctttctgcat catgaccaca aactcacaaa aaggaatgcc actctcaatc
    45781 aagtgcatga gaataggcgt cgtgatgtag taaggcaaat tagccactac cttgattggc
    45841 aggtcaggat ttttaaaatt ctggatatgt tgcgccaaat caaccttgag aatatcttcg
    45901 ttaactacgg tcacattatc aaaatcacgc agggtatctg ccaaaattgg caccaaacgg
    45961 tggtcaatct caaaagccat gacttgggct gcacgctcag ccaaaaattc tgtcaaggca
    46021 ccaatacctg gcccgatttc gatgacattg acctgatcat caatttcagc cgtatccaca
    46081 attttttgaa ggatattggt atccgtcaaa aaattttgcc caaaggactt tttaaaggta
    46141 aaaccgtgac gctccagcac tgccttggtc acgctataat ctgcaattct catctattct
    46201 cttttctatt atctgttact actattgtaa cacattcccc ttgtattttg ggaatgaaaa
    46261 tcataccaaa aaactatctt tcctcatgaa gaaagatagt cttggaaatc tttaaaagtg
    46321 gccttagcag ttctctcgaa acatgcgttc aaaaaaatca gcttcttgat aacttcgatt
    46381 ttcaggtagg gtcaaatcca catcctcctc cacatcatcc actgtcagtt caaccgtctg
    46441 aggtaaattt ttcaaacgat aatgcttttg cctttgccct tcaatactag caaaatcaag
    46501 caaatagcca tgcactcgga tttgaaccaa aaggagatga ttggtcatat tttccatgat
    46561 gaggatatct tctaaaccac ctctggcact aggataatca gataccctgc gaatacggat
    46621 tttttcacac atgagcaagt ttcctcatat caatgatttc atcagcctta ttccagacta
    46681 ggggattatg ggtcgcaatg atgataattc gattttcatc tttcaaatcc accaagagat
    46741 tcataacctc ctctgaattt tcaggatcaa gagctgctgt tggttcatct gccaaaatca
    46801 agggtggatt tttcaaaata gtcttagcaa gggcaactcg ttgggcctct cccccagata
    46861 aagtatagat tttttgttct aaatccaaat accctagatt aactttttct aaagccccca
    46921 cttgcctttc caaacgttct acttttgaga ttttctgacc aacaaaaccc aaatccaaat
    46981 tttctttgat tgattggttt tctaagaggc cgaaattttg aaagagatag cccatctggt
    47041 ctcgaaaata ctcacgagtg ggaatggttt ttaaatcttt cccctgatag agaacccttc
    47101 caccatctat cttttctagc tttcccaaga tattcagcag cgtcgtcttt ccgcttccac
    47161 tctttccgat taaggcataa accttgccct tctccagctt gagattcaaa ccagagaaaa
    47221 tcgcgcggtc attaaatttc ttttccaatc cttgaatatc aatcatctta ttttcctttc
    47281 aatactgcca tgctaccagc ttcttctttt ttgtcctgcc ttactaaaat caagagggcg
    47341 ttaagcgtaa acaaagctac aactagagcg ctaatcaaac catctcttgt caaaatacta
    47401 gataggacta ggccaagcaa gagaactcct ccttgcgcca gtaaatactt gccatgaagc
    47461 tcatagattg tcataccagc aagacgttta atcataagtt cccgtctgaa ctgctcaaaa
    47521 tagagaagat tcatggaatc aaataacaag atagccgtag acagggtcaa aatcgtccca
    47581 ataaggagag agtaaaactc cacccgtttg tcatttagta ccttggcaaa aaatagctgg
    47641 ctttttacca agtaagaaac cttgtgatac agacctttct cttttagagc tgtgatgctg
    47701 tctccatatc gatctagttt caaggcacta ttagccgtag ttccccacaa catccctgca
    47761 acaggtcttg ttccagtcgc ttgcggcgtt agaactacaa taatcggatc ttttaggtac
    47821 tggcgtgttg tcttgtaccc atcattatag aggaaacgtt cctgtcctgt ttctgtaaaa
    47881 gctagcctta cctgtgggag gtagtgtttc tgactcgtca cttctacact ttcagatgaa
    47941 aagttttgca ggtaatctgt aaacaatcct tggtagtaga cagactgctc tcgcaagctc
    48001 tcaggcaaga tcagcccaaa ctctccctca gacaagtttt gcatcttgtc cataaactct
    48061 gaagaaacgg taatcttttc ttctatcaga tagcgcggtg agacatagat aacattccct
    48121 gacggtgtgt agtcactgag acgattgcca tctaggtcca cttctgctcc atctgagaaa
    48181 ttgtcaacat tgctcataat ataaaaagag tctgtattgg ctaaccgttc ttcagtaaat
    48241 gtctgccact cacgattatc cttacgcgtt ccttcttcat cggcaaatgc actagaccaa
    48301 ccaaaggata gacggtaacg gtctgaggac tggctccatt tattgctagc tctctccatt
    48361 tcctgcattt cacggtagtg gggtaggaga gctgtcgcac tcgatccgac caccaataca
    48421 gctaagagtt gccccaccat catcaatgtc atcatacgtt tgagagggag tttccctttc
    48481 aatagatcca ccagactatt ttcctgtaaa ccaagtagat agacgacact tagtaaggta
    48541 gaaatccctg ccaaggtcaa tccataaagt agaagagcaa tgatgaccag ttgcaccgtt
    48601 gccataaaca aggcaccttg ataccagaga atccccaatc ccaaaagact ggataccagc
    48661 actgagcaga taagctgtct cacatcttct aacactggtc tgagagcaac tccaaacaag
    48721 ctctcaccag ctattaagcg aatccctgcc tgacgaaggg atttgatccg ataaatcagg
    48781 gtcagactca taaaggtcag cagaaaaata gctaaactca gtagcaccat aggggtggcc
    48841 gtcaatagta agactatcga aaatggatct tctccattcg aaacaaagcc ttgataacca
    48901 agctctttca aggtggtctg taagctcact ccatccaaac ttcctgatac aatcaagtaa
    48961 gaccctaata aatcactcgt ttctgcactc tccttggagg aaatggtcag accttctgga
    49021 agctttccct caccataagt ggcataggta aagcgtgttt ctccagcttc atttggctca
    49081 acgattcgac gagcaatgag actattgtgc tctaccgcca agtgactcaa agcctctgtc
    49141 acctcttcgc gactagctac tggttgattt atcatcattc ctgtcacatc aacagaagga
    49201 tagttaccaa ataaaatctc ttctcgatgg tcaacggaag ttatcaccat ataaagcgat
    49261 actaatacca ttgaaatcaa aataaataaa cgtttcatca tttcctccaa aaagttactt
    49321 ggtcacttcg tgagaaggtg accacagtca ctgcgatgtt aagaagctta ttaagttctt
    49381 tctgctagca acatcttcaa atacattata tccgtttttt caagaactat caaggacatc
    49441 aatgtcctta aaatctaacc atttcgtgtc atttttagct tatatctaaa aaaacatccc
    49501 taaagacgaa ctttagaact gttttgatac gaggacaagg acatctttgt cactgattca
    49561 ctatgtttat aaatattttt tgacatcctc ttgccattcc tctgtcaatt tctttactag
    49621 aaattcatct ccaattagct gcgcaaatgt tttagaagac tgataaaatg attcagctaa
    49681 actaaaatct ctttcttctc ttaatgcttg cttccacaaa aacataaata caagaggttt
    49741 cttttgataa tcttgagttt tatccataat ttcttgtaaa cacgatagat aatcattaaa
    49801 acaatcagtt actcctacct tttcaagaca acacattcct gaaataagag tatctctaat
    49861 tataaagtaa ttctctattt gagttacctt cttctgttcc aaaagaaaga gcattagctt
    49921 ttcgatttga tttataaatt tggcaagatc ttttctaatg agcatttgat aaaaaaacaa
    49981 acgaatcaac aacatatcat ttattgaata agcttctttt tctataatct gaggcatatg
    50041 ttcctcaagt attaactctg catattcagg ccttctagtt ctagaagtat ccaaacacgc
    50101 ctgcaatact tcacatgcta attgttcttc tttaggaaga ttatcaaagt atgttttata
    50161 aatctcttcc aaacacgctt ccttcttatc gtactcctct tctttaccat agattggttc
    50221 acgtaaaatc tggtatttca attctaaata agcagaagga agagctgaaa aatccggcat
    50281 aaggctataa actggaactc ctagccggcg agcaatatag tctaacttgg gcaaactcgg
    50341 ttgcgaagct ccactttcaa ttcgcgacag ttgacgaact gtcagttctt gctcatctcc
    50401 acaaaaatct ggacgactaa ttcctttttc tatccgaatc tctttaattt tttgaccaat
    50461 taacatcaga cgcctcctct tctacctgct tcgaaaaata ctgtgaaact taaaaaattg
    50521 taacggctac atctttccta ctcataagat ttcatagctt cttccacttc tgccaaagta
    50581 accccaaaca actctaggcg tttgaggagt tgcttgccgt tggaatagcc gattcggaga
    50641 gtctctccga gatattctct acgcttacgg ctgtctgccc ctgctagaaa accaaggcga
    50701 atcaaatcgc tacgactaat gtcaaactga ctctcatgtt caaattgttc tgtcacttga
    50761 gctagagccg ttttcaggtc ttcatagctg gcatgctcaa ttcccagaga acgccccttg
    50821 gtcttggact tgggaacagc ttcatctcgc ttgagaaagg catgctgaac tgttggaatg
    50881 accatcatga tcatgcgccg aatccgttcc ccattaaaat ctgggtctgt aaagacaatg
    50941 actccatgac gttggtgcag gcgctgaatc cgctctatat cctgagcatt gatggcagaa
    51001 cctcgagtct cataggtctc cacatcgaaa taacgtttga gattgaccgt atcatcacgc
    51061 ccttcaacca cgataacttg agaaattttc tctttcatta cttgctgtcc agtccaaaaa
    51121 ttcgttctgc atttgcagtc gttgctaccg ccagctcttc tgtcgtcata ccacgcaagt
    51181 cagcgataaa gtcgaccaca tagcgagtat aggctgtttt attttcacga ccacgcttgg
    51241 gtacaggtgc taagtaaggc gcatctgttt ccaccaacat cttgtccaaa ggtaactctt
    51301 tagctgcttc ttggaggtca gttgccttct taaaagtcac cactcctgag aaggaaatgg
    51361 tcataccaag atccacaaac ttctctgccc actcaagcgt ccctgaaaat gaatgcatga
    51421 taccaccacg aggaccaacg ccctcactct tgataatctc ataggtatct tccagcgcat
    51481 cacgggtatg gacaacaaaa ggcaaatcca agtccttaga tagctgaatc tgacggcgaa
    51541 aaacctgctc ctgcacctct ttgggcgctg tcatccaatg gtaatctaag ccaatttcac
    51601 ctaaagccac aaccttggaa tgttttaact tatccaacaa gtaagcctca acttcctctg
    51661 tataagtacc agcttctgta ggatgccaac caatagtcgc atagagctgc tcatactcat
    51721 ctaccaactc caaggcatgc tcaatcgtcg gtttatcaaa accaacaata ttcatctgtg
    51781 tcacacccat ctcagcagcc aaggcaattt cttctgcctc acgacctgca aattcttcta
    51841 cattcaagtg tgtatgtgta tcaaaaatca tctcttctaa cctcgttttc tatcttctat
    51901 tataccaaaa aagaggaggg gcacctaatt tttcggtttc ccctcctctc ttcaatagag
    51961 agctattctg ctatcttttc tatccgatat tgcccatctc ctattccaca gttagagaca
    52021 gaagagattg gctacattga tagaatattc ctattcagct aaagtatgtg attatcttgg
    52081 gttctcactt ttctcaccca tcactaggat tgatgacttc tcaaaatccc ccttataatc
    52141 taactttaag tagagaatag aattttctag ctgttctatt ttctacgtct agtctttctt
    52201 cctagcaaag caaaaccact tgttgccacc actagaccaa gactagcaag tgctgcactt
    52261 gatgctgaac ctgtgttagg taattgtttg ccagcaggtg actggtaggt aacatcttgc
    52321 attgttcctg cagttgcttg cggtgcactt gttgtcttag gagcagcatt aggagccact
    52381 ggtctcttag gaactgtaac catggcaatg gcttgcactc caatcgtttc tgcttccttc
    52441 acatcttcca tagttttcgc attttcaatc tctttgagag ctgcttgttt ttctgcttcc
    52501 actcttgcta aaagttctgc tttttcttta tcagaaagcg gtgcgccttt gatttcatcc
    52561 tgcttgtcct tggctgcttt ttcaatggca tttttagctg attctttttc agtagctaat
    52621 tgcttagaag cttgtgattg agctgagttt tgtgaacctg tgtgagctga tccacccgcc
    52681 tggctaccac cgccttcatt cgcattagca tctgagcttc cagtattgcc tcccttatct
    52741 ccacctggtg tattttctag cttatactct ggtgtagctt cttgagttac agattcacct
    52801 ttcgcagatt gttgaactgt atcttttcct agaatcgtca ctactgaacc atctgggaat
    52861 gtgattgttg ctgtaccatc tccagctaca ttgattgtcg ctccgtctaa tgctgaacca
    52921 tttgcttgta aaatagcaac cttaactttt tcttcatctg ttaaatgagt tatatctttt
    52981 acatctactc tttgagcagg tgctttaaca gttgattttt cagcagtcag tttagtgcta
    53041 tcttgtgctt ttggatcttg tgctaccaat tgatttcctg gaattgtaat agctgaacca
    53101 tctttaaaga cgattgttgc tgtaccatct ccacctactt caactttata gtaaaataaa
    53161 ataataacag gacaaatcga tcaggacagt caaatcgatt tctaacaatg ttttagaaac
    53221 agaggtgtac tattctagtt tcaatctact gtaacatcgc ttccgaatcc atttgcatct
    53281 actgaacttt tttacaaaaa taaaaatcag tagactcgag ttcctactga tttttgatag
    53341 aattcgtttg gattatgcag ccaaaacttt gcgtccttta cgacgacgag ctgccaatac
    53401 gcgacgacca tttttagttg acatacggtt acggaatccg tgtttgcgcg cacgacgaag
    53461 tttacttggt tgataagtac gtttcacgat gaatacctcc tcatagattt tgtattcgtt
    53521 tagccggcta taaagtgatc agttactaaa catactttac tattctatct gattctttca
    53581 cttttgtcaa tagctctagg caaatgtttc cagctttttc gaatgcaagc cctatctacg
    53641 atactgtttc aagaaacgag tcatcttttc ttggatttgg gctaactcat caacacgagg
    53701 aaggtaaacg atacggaagt ggtctggttc ctgccagtta aagcctcgac catgaaccaa
    53761 gagaaccttt tcctgcttca agaaatcaag gacaaactgc tcatcatcat cgatacggta
    53821 catattgcgg tcgatttttg ggaagatata gagccccgcc ttgggtttaa cggcagacaa
    53881 acctggaata tcttgaatgg cattatagat gaaatttctt tgctcgtaga ttcgtccacc
    53941 aggaagaagc aattcatcga ctgattggtg accccccaag gaagtttgta cgacttgttg
    54001 ggccaaaacg ttagagcaaa ggcgcatatt ggacagcata ttgagccctt cgatatagcc
    54061 cttaacatga gtcttagggc cagacaagac catccaaccc acacggaaac ctgctatgcg
    54121 gtgggatttt gacagaccat tcatgctgac acagaagaca tctggtgcca agctcgccac
    54181 aggcgtatgc acatgtccgt ccattaccat gcggtcatag atttcatccg caaagataat
    54241 caaatcgttt tgacgggcaa tctcaataat ctccagcaag agttccttag gataaagggc
    54301 tccagttggg ttatttggat tgataaggac aattgccttg gtattggaag tgatttttga
    54361 cttgatatcg tcaatatctg ggtaccattc cacagcttca tcacagatat agtgaacggc
    54421 atttcctcca gctaggctga cagccgccgt ccatagagga tagtctggca ttggcactaa
    54481 gacctcatcc ccattgtcca aaagcccctg catggacatg acaatcaact cactgacacc
    54541 atttccaagg taaatatcat caatatctac gtttgggaat ttcttcagct ggcaatactg
    54601 catgatggcc ttacgggctg agaaaatccc tttggagtca gaatagcctt cactatcacg
    54661 cgcattcata atcaagtcat gaatgacctc gtctggcgct gtaaagccaa attctgctgg
    54721 atttcctgta ttcagacgta aaatcttttc tccattcgct cgcatccgca tggcttcttc
    54781 caatacagga ccacggatat cataagcaac atgctctaac ttactagact tgttatattc
    54841 tttcatcttg tttcctcaat tcatcaggat agtaacatta taccactaga aagagaatgc
    54901 gacaagttta ctgaaatgtg ttactagttt cgtatagaag aaaaaccttg ctaaaggcga
    54961 ggttaagaac gtagagatag caggtatttt gcaaagacac atcacatacc aaaagataaa
    55021 cctagaaaaa agcaagccta gaaaggagtc ataaagaaga ttaaacatga ggaaaagccc
    55081 ccatatcatc aagtaatccc aacgcccact tcgttttgca actagaaata agattagatg
    55141 gtagagtaca tgaaaaacta aaaatccaat aaaacttgga taaagaagcg gtaccagact
    55201 ctctaattga cagatcatga tcacttctac caagactgaa actaggataa ttccataata
    55261 aaggaaattt gatttttgaa aagagttttt catcattctc ccttccttca cttctttcct
    55321 gctatccttt cttttatttt atcatatatt tatatagagt ttaagcccta atattctttt
    55381 gaaaaatact ttttttgctt tacttctata gtgaaaaggt ttacaattat agtaagaaaa
    55441 tttcaggagg tttcattatg gcacaacgtt accaaaatat catggtcgca atcgatggtt
    55501 ctaaggaagc ggacttggct tttgtcaagg gagttcattc tgctctacga aacgacgcta
    55561 aactcaccat cgcacatgtc attgacacac gcgctctcca aagcgtatcc acctttgatg
    55621 ctgaagttta cgaagaactc caagtcgacg ctgaaagtct gatgaaagag tacgaaaaac
    55681 gtgctaaaga tgctggggta gcagatgttc atatcgtcat tgaaatggga aatccaaaga
    55741 ccctgctagc acgtactatt ccagatgccg aggaagtgga cctcatcctc gttggcgcaa
    55801 ctggtctcaa cgcctttgaa cgcctcttgg tcggctcttc atctgaatac atactccgcc
    55861 atgctaaggt cgatttgctg gttgtgagag aacaagaaaa aaccttataa tcacaaagaa
    55921 aaggagcccc tagctccttt ttgtttacga tttatttctc tctttatggc gttcgtaagc
    55981 cttgagctgg cgctgcagtt cctttttaat agcaggttct ggagcatatt tttcttccca
    56041 attatctggt tttaagattt tatgggtcac tggatcaaaa tgagccttgc catctggaaa
    56101 aattttcccc atattggcct gatggacaat atcaaaaata cgttctgggt ccacccccat
    56161 caagacaaaa ctgccgtagg tgaagtaaag cgtgtcaatc aaggcatcca cttgccctat
    56221 caaatcttgc tgagcaggtg tcttcttggc tactttatct gctgccttat caagggcctg
    56281 atgaagttgc gatacagctt gaccaaaatc ttcttcagaa ggactggctg ctcgaacaaa
    56341 ctccaccaat tcttctattt taaaaccagc cctatgggtt gcaccctcta aatcccaagc
    56401 tcgaggttct tcttgggttc gttcatccat catgtggtgg aaggtcttga ccttattgaa
    56461 atgatagtca cggctgacaa agactttttc tgaagacaaa acaccaaaat gttccaaggc
    56521 cttgtggatt ccatcttgtt gattgctagt ggtaatgtgc ttggcagctt ccttgacact
    56581 gctactacca tttcccatag cgaccgacat accaacgcca gccagcattt caagatcatt
    56641 atctgagtca ccaaaagcca tgacttggtt gaggtcaaag ccatattctt tcccaactcg
    56701 gcgaatgcct tctaatttag aatttccctg attgatgaca tccgatgcaa aaggattgct
    56761 acgtgtcaat ttcaagtctt caaaatcagc tgccgccttc tcagattctt ctggtgtcat
    56821 cagcatcaaa acttggtaga taggctgatt catcaggtga agcaggtcct cttccttttg
    56881 gggaacaacc ttgctgacca tgcgattaaa agactgactc accgtccgag ttaaaacaga
    56941 gggaacgaag cgactaattc gttgggaaaa agaacccaga ccaaaggaca tgattttaga
    57001 acccaacatg gcatccttgg tccctagagc aatctccgtg ccctcttttt tagcatagct
    57061 aattagatgg cgcaaatgta acttggaaat agggctcgtg aacaagactc tgtctttact
    57121 aaagatatac tggccattat aggttaccgc aaaatccaga tccaaatcgt ccatcaattc
    57181 cttaacaaaa aaaggtcctc gccctgtcgc tacgccaact agtacccctt gttctttgac
    57241 aatcttaatc gcatccttag tggatttcaa aacactcttg cgattgttga ccaaggttcc
    57301 atcgatatca aaaaaaacag ctttgacttc catcctatcc caatctcccc ttttgtgata
    57361 caatgattat accacatttc agaaagagtg agtaaatcat gcctaagaaa atccttgttt
    57421 tacatacggg tggaactatt tccatgcagg ccgatgcttc tggcgctgtt gtgacgagtt
    57481 cagataatcc catgaaccat gtgtccaacc cacttgaagg aatccaagtc cacgccttgg
    57541 acttttttaa ccttccaagt ccccatatca aacccaaaca tatgctggtc ctctaccaga
    57601 aaattaaaga ggaagcagat aactacgatg gagtggtgat cacacacgga accgatactt
    57661 tagaggaaac agcctatttc cttgatacca tggaagttcc ccatatgcct atcgttctaa
    57721 caggagccat gcgtagctcc aatgagctcg gtagtgatgg tgtttataat tacctaagtg
    57781 ctttacgagt ggccagcgat gacagggctg ctgacaaagg agttttggtc gttatgaacg
    57841 atgaaatcca cgctgccaag tatgtcacca aaacacatac gactaatgtc agcaccttcc
    57901 agactccaac acatggcccc cttggtctca tcatgaaaca ggaaatcctc tacttcaaaa
    57961 cagctgaacc tcgtgttcgc tttgaccttg atcacataca aggtttagtc cctatcatct
    58021 cggcttatgc tggtatgaca gatgagctga ttgatatgct ggatttagaa cacttggacg
    58081 gtttgattat ccaagccttc ggagctggta atattcccaa agaaacggct caaaaattag
    58141 aaagccttct gcaaaaagga attccagtcg ctctggtatc acgatgcttt aacggtattg
    58201 ccgagcctgt ttatgcatac cagggtgggg gcgtacagtt gcaaaaagca ggcgttttct
    58261 ttgttaaaga actcaacgcc caaaaagctc gcttgaaact cctcatcgcc ctcaatgccg
    58321 gactaacagg acaggctttg aaagactata tggaaggcta atactcttcg aaaatctctg
    58381 caaaccacgt cacgtcgcct taccgtatgt atggttactg acttcgtcag ttt
//
LOCUS       DAVFER010000008        55733 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1105170250
            SAMEA2167659-rid19724873.denovo.008, whole genome shotgun sequence.
ACCESSION   DAVFER010000008 DAVFER010000000
VERSION     DAVFER010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2167659
            Sequence Read Archive: ERR388902
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 55733)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 55733)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928716.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928716.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 04:07:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,118
            CDSs (total)                      :: 2,073
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 120
            CDSs (without protein)            :: 120
            Pseudo Genes (ambiguous residues) :: 0 of 120
            Pseudo Genes (frameshifted)       :: 67 of 120
            Pseudo Genes (incomplete)         :: 47 of 120
            Pseudo Genes (internal stop)      :: 34 of 120
            Pseudo Genes (multiple problems)  :: 23 of 120
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..55733
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2167659-rid19724873.denovo.008"
                     /strain="1105170250"
                     /db_xref="taxon:1313"
     gene            complement(126..995)
                     /locus_tag="VU534_000485"
     CDS             complement(126..995)
                     /locus_tag="VU534_000485"
                     /EC_number="2.7.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000692406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine kinase"
                     /protein_id="HEU1513118.1"
                     /translation="MKIIVPATSANIGPGFDSVGVAVTKYLQIEVCEERDEWLIEHQI
                     GKWIPHDERNLLLKIALQIVPDLQPRRLKMTSDVPLARGLGSSSSVIVAGIELANQLG
                     QLNLSDHEKLQLATKIEGHPDNVAPAIYGNLVIASSVEGQVSAIVADFPECDFLAYIP
                     NYELRTRDSRSVLPKKLSYKEAVAASSIANVAVAALLAGDMVTAGQAIEGDLFHERYR
                     QDLVREFAMIKQVTKENGAYATYLSGAGPTVMVLASHDKMPTIKAELEKQPFKGKLHD
                     LRVDTQGVRVEAK"
     gene            complement(997..2283)
                     /locus_tag="VU534_000486"
     CDS             complement(997..2283)
                     /locus_tag="VU534_000486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine dehydrogenase"
                     /protein_id="HEU1513119.1"
                     /translation="MTVKIALLGFGTVASGVPFLLKENGGKINQSAHSDIKVAKVLVK
                     DEDEKNRLLAAGNDFNFVTNVDDILSDQDITIVVELMGRIEPAKTFITRALEAGKHVV
                     TANKDLLAVHGAELLEIAQANKVALYYEAAVAGGIPILRTLANSLASDKITRVLGVVN
                     GTSNFMVTKMVEEGWPYDDALAEAQRLGFAESDPTNDVDGIDAAYKMVILSQFAFGMK
                     IAFDDVAHKGIRNITPEDVAVAQELGYVVKLVGSIEETSSGIAAEVTPTFLPKAHPLA
                     SVNGVMNAVFVESIGIGESMYYGPGAGQKPTATSVVADIVRIVRRLNDGTIGKDFNEY
                     SRDLVLANPEDVKANYYFSILALDSKGQVLKLAEIFNAQDISFKQILQDGKEGDKARV
                     VIITHKINKAQLENVSAELKKVSEFDLLNTFKVLGE"
     gene            complement(2434..3171)
                     /gene="mecA"
                     /locus_tag="VU534_000487"
     CDS             complement(2434..3171)
                     /gene="mecA"
                     /locus_tag="VU534_000487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000782680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HEU1513120.1"
                     /translation="MKMKQISDTTLKITISLEDLMDRGMEIADFLVPQEKTEEFFYAI
                     LDELEMPDSFLDTGMLSFRVTPKPDKVDVFVTKSKIDQNLDFEDLSDLPDMEELAQMS
                     PDEFIKTLEKSIADKTKDDIEAIQSLEQVEVKEEEQEQAEQEAESKKEPYIYYILSFA
                     KLADLVAFAKTVTFEMETSELYKMNERYYLTILVDIENHPSPYPAWLLARMREFADDS
                     DISRSVLQEYGQVLMSHDAVLNLQKIG"
     gene            complement(3371..4405)
                     /locus_tag="VU534_000488"
     CDS             complement(3371..4405)
                     /locus_tag="VU534_000488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HEU1513121.1"
                     /translation="MFEHYSVADLFANLYKKRKANILALIALFALIAVPFTIKAVRNK
                     NTVKDTTSYSTYLIYKITPPKESDKTILNHQIGGYSDFYGKLIDGNLNGAYLFNDVEP
                     SELKKIASELDTTETTLKNSTNDYWWKKLTVYYMIDDAGVGVKILTSSKDANNLLEKK
                     IDGLIEKFKHAYANVKIEKLETINSKELNANGETALGLNVKNLILRLVVIGVVCVILV
                     VMGNVLVYLFNPTINRVGDFSQYQIDFVTEITTIANLADVLSYKNTGQELTIVSSNKA
                     ILDKLKQSQEALKGMHFVDLQDVSSLLERDTVLLVEEYGVTRYKKFEQSLQILRNLNR
                     SILGVATFKL"
     gene            complement(4434..5867)
                     /locus_tag="VU534_000489"
     CDS             complement(4434..5867)
                     /locus_tag="VU534_000489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen polysaccharide polymerase Wzy family
                     protein"
                     /protein_id="HEU1513122.1"
                     /translation="MIDGKRLLFSLTIVSYALTLVSGIVYLFNNNNVSLLSTLLFLLV
                     SSLIACWNDIKYYLIHFIFYLTIFVFLVSRPTIDYFRDGALDTYHPIAYRFAFIVVMI
                     SILGLTTGGILARYFIARKKIKVANIGNSLKEVYIKRLRFVSLGVFLLTYPFYFIRLF
                     ERLLYRLQTSYYAYYANFESKLPYFTYILSTFTVYAMCMYLATKPKKLQATAVLVSFI
                     AANTIHLAIGTRNPFILSILFAFVYYFMREQTEKGKWIGFKEKLAIFVGSPILMLAMG
                     VLNYVRDNVQVSHTGFWDILLDFIYKQGTSFGVLARGFLFNSSLPYRDFRNFTFGPVL
                     DYFARGSLGAIFGGKAFEHTTNSVELAIDSNSYAHNLSYLVLNKEYLKGHGIGSSYIM
                     ELYTDYGMIGVFLLSFLLGVLFIAMLQVAYRSRTILFALSLLILNNLFFMPRSSFSES
                     FFNLFTMQFWGIVLVIIFVAKMLTKEN"
     gene            complement(5883..6869)
                     /locus_tag="VU534_000490"
     CDS             complement(5883..6869)
                     /locus_tag="VU534_000490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000446977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEU1513123.1"
                     /translation="METALISVIVPVYNVAQYLEKSIASIQKQTYQNLEIILVDDGAT
                     DESGRLCDSIAEQDDRVSVLHKKNEGLSQARNDGMKQAHGDYLIFIDSDDYIHPEMIQ
                     SLYEQLVQEDADVSSCGVMNVYANDESPQSANQDDYFVCDSQTFLKEYLIGEKIPGTI
                     CNKLIKRQIATALSFPKGLIYEDAYYHFDLIKLAKKYVVNTKPYYYYFHRGDSITTKP
                     YAEKDLAYIDIYQKFYNEVVKNYPDLKEVAFFRLAYAHFFILDKMLLDDQYKQFEAYS
                     QIHRFLKGHAFAISRNPIFRKGRRISALALFINISLYRFLLLKNIEKSKKLH"
     gene            complement(6871..7974)
                     /locus_tag="VU534_000491"
     CDS             complement(6871..7974)
                     /locus_tag="VU534_000491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000225894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HEU1513124.1"
                     /translation="MVAKKKILFFMWSFSLGGGAEKILSTIVSNLDPEKYDIDILEME
                     HFDKGYESVPKHVRILKSLQDYRQTRWLRAFLWRMRIYFPRLTRRLLVKDDYDVEVSF
                     TIMNPPLLFSKRREVKKISWIHGSIEELLKDSSKRESHRSQLDAANTIVGISKKTSNS
                     IKEVYPDYTSKLQTIYNGYDFQTILEKSQEKIDIEIAPQSICTIGRIEENKGSDRVVE
                     VIRLLHQEGKNYHLYFIGAGDMEEELKKRVKEYGIEDYVHFLGYQKNPYQYLSQTKVL
                     LSMSKQEGFPGVYVEALSLGLPFISTDVGGAEELSQEGRFGQIIESNQEAAQAITNYM
                     TSASNFDVDEASQFIQQFTITKQIEQVEKLLEE"
     gene            complement(7964..8809)
                     /locus_tag="VU534_000492"
     CDS             complement(7964..8809)
                     /locus_tag="VU534_000492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HEU1513125.1"
                     /translation="MNNMTDLKAIQARSLEMAEYFVAFCKEHDLLCYLCGGGAIGALR
                     NKGFIPWDDDLDFFMPRKDYEKLAELWPRYADERYFLSKSHKDFVDRNLFITIRDKKT
                     TCIKPYQQDLDLPHGLALDVLPLDYYPKNPAERKKQVRWALIYSLFCAQTIPEKHGDL
                     MKWGSRILLGLTPKSLRYRIWKKAEKEMTKYDLADCDGITELCSGPGYMRNKYPITSF
                     EDNLFLPFEGTEMPIPIGYDVYLRTAFGDYMTPPPADKQVPHHDAVIADMDKSYTEYK
                     GEYGG"
     gene            complement(9088..10362)
                     /gene="psr"
                     /locus_tag="VU534_000493"
     CDS             complement(9088..10362)
                     /gene="psr"
                     /locus_tag="VU534_000493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyisoprenyl-teichoic acid--peptidoglycan
                     teichoic acid transferase Psr"
                     /protein_id="HEU1513126.1"
                     /translation="MSKENPLSHHEQLRYDYLLKNIHYLNEREKNEFAYLQEKLTLAR
                     GNSSSSLEQEREEQVDLPSYANRSRSQSKSQALSFPPKKKRRKLRLKRIFMVIFSLLV
                     CVALAMVFMFLRGYQDASAKKTADARAAQVEVFNGQDTRDGVNILIMGTDGRIGQNSV
                     ETRTDSIMVLNVGGSDKKMKLVSFMRDNLVYIDGYSQVINGRKQTDNKLNVAYELGEQ
                     EGQKGAEMVRQVLKDNFDLDIKYYALVDFQAFATAIDTLFPDGVTIDAQFSTLNGRPL
                     TEATVGDDLYATETESPTQTIKVGKQQMNGSTLLNYARFRDDDEADYGRTKRQQQVLT
                     AILEQIKDPTKLFTGSEALGKVFAMTSTNVPYTFLLTNGLSVLDGAKNGIEKLTIPEL
                     GDWVDAYDVYGGLGLLVDQNKYQTKLAQMGLR"
     gene            complement(10359..11207)
                     /gene="pheA"
                     /locus_tag="VU534_000494"
     CDS             complement(10359..11207)
                     /gene="pheA"
                     /locus_tag="VU534_000494"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HEU1513127.1"
                     /translation="MKIAYLGPKGSFSHHVVQTAFPHEELQAFANITDVIKAYEQGLV
                     NYSVVPVENSIEGSVHETLDYLFHQAHIQAVAEIVQPIHQQLMVVPGHTKIEKIFSHP
                     QALAQGKKFIDEQYPEAQIEVTASTAYAARFISEHPDQPFAAVAPRSSAEEYGLELIA
                     EDIQEMEANFTRFWVLGAEKPSIPLQAQTEKMSLALTLPDNLPGALYKALSTFAWRGI
                     DLTKIESCPLKTALGEYFFIIDVDYTDKDLVHFAQKELEAIGIQYKILGAYPIYPISD
                     HGKERR"
     gene            complement(11204..11680)
                     /locus_tag="VU534_000495"
     CDS             complement(11204..11680)
                     /locus_tag="VU534_000495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HEU1513128.1"
                     /translation="MAKVLLGFMGAGKSTIARGLDPNYLDMDALIENRLGMSIANFFA
                     EKGETAFRQVESEVLADLLQTDQVVSTGGGVVISQRNRDLLKTNTDNIYLRADFETLY
                     QRIAADKDNQRPLFLNNSKEELVAIFQERQAWYEEVASRVLDVTKLSPEEIIEELR"
     gene            complement(11673..12956)
                     /gene="aroA"
                     /locus_tag="VU534_000496"
     CDS             complement(11673..12956)
                     /gene="aroA"
                     /locus_tag="VU534_000496"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004236106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HEU1513129.1"
                     /translation="MKLKTNIRHLHGSIRVPGDKSISHRSIIFGSLAEGETKVYDILR
                     GEDVLSTMQVFRDLGVEIEDKDGVITIQGVGMAGLKAPQNALNMGNSGTSIRLISGVL
                     AGADFEVEMFGDDSLSKRPMDRVTLPLKKMGVSISGQTERDLPPLRLKGTKNLRPIHY
                     ELPIASAQVKSALMFAALQAKGESVIIEKEYTRNHTEDMLKQFGGHLSVDGKKITVQG
                     PQKLTGQKVVVPGDISSAAFWLVAGLIAPNSRLVLQNVGINETRTGIIDVIRAMGGKL
                     EITEIDPVAKSATLIVESSDLKGTEIGGALIPRLIDELPIIALLATQAQGVTVIKDAE
                     ELKVKETDRIQVVADALNSMGADITPTADGMIIKGKSALHGARVNTFGDHRIGMMTAI
                     AALLVADGEVELDRAEAINTSYPSFFDDLESLIHG"
     gene            complement(13048..13386)
                     /locus_tag="VU534_000497"
     CDS             complement(13048..13386)
                     /locus_tag="VU534_000497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000065990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF/YmcA family competence regulator"
                     /protein_id="HEU1513130.1"
                     /translation="MSNIYDSANELSRGLRGLPEYKAVKAAKDAIAADAEASKIFTDY
                     LAFQEEIQKLAQTGQMPDASFQAKMEGFGKQIQGNSLLSEFFTKQQQLAIYLSDIEKI
                     VFEPVSELLK"
     gene            complement(13397..14500)
                     /locus_tag="VU534_000498"
     CDS             complement(13397..14500)
                     /locus_tag="VU534_000498"
                     /EC_number="1.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HEU1513131.1"
                     /translation="MAKTIYIAGLGLIGASMALGIKRDHPDYEILGYNRSQASRDIAL
                     KEGMIDRATDDFASFAPLADVIILSLPIKQTIAFIKELANLDLREGVIISDAGSTKST
                     IVDAAEQYLAGKSVRFVGAHPMAGSHKTGAASADVNLFENAYYIFTPSSLTSQDTLKE
                     MKDLLSGLHARFIEIDAKEHDRVTSQISHFPHILASSLMEQTAVYAQEHEMARRFAAG
                     GFRDMTRIAESEPGMWTSILLSNSEIILDRIEDFKERLEAIGQAISKGDEEQIWNFFN
                     QAREQRQTMEIHKRGGVDSSYDLYVDVPDEEDVILRILELLRGTSLVNIHINEENRED
                     IHGILQISFKNAQDLERAEHLITENTDYTVVIK"
     gene            complement(14510..15676)
                     /gene="aroC"
                     /locus_tag="VU534_000499"
     CDS             complement(14510..15676)
                     /gene="aroC"
                     /locus_tag="VU534_000499"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HEU1513132.1"
                     /translation="MRYLTAGESHGPRLTAIIEGIPAGLPLTAEDINEDLRRRQGGYG
                     RGGRMKIENDQVVFTSGVRHGKTTGAPITMDVINKDHQKWLDIMSAEDIEDRLKSKRK
                     ITHPRPGHADLVGGIKYRFDDLRNSLERSSARETTMRVAVGAVAKRLLAELDMEIANH
                     VVVFGGKEIDVPENLTVAEIKQRAAQSEVSIVNQEREQEIKDYIDQIKRDGDTIGGVV
                     ETVVGGVPVGLGSYVQWDRKLDARLAQAVVSINAFKGVEFGLGFEAGYRKGSQVMDEI
                     LWSKEDGYTRRTNNLGGFEGGMTNGQPIVVRGVMKPIPTLYKPLMSVDIETHEPYKAT
                     VERSDPTALPAAGMVMEAVVATVLAQEILEKFSSDNLEELKEAVAKHRDYTKNY"
     gene            complement(15686..16753)
                     /locus_tag="VU534_000500"
     CDS             complement(15686..16753)
                     /locus_tag="VU534_000500"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HEU1513133.1"
                     /translation="MKIRIDIPHHPYDIQIEKGCMAQAGQWLRELWQPQKVVIVTDNH
                     VASLYAEKVKLSLEDAGFQVAVFDFLEGEERKNLTTVQKVYEFLVKQGLTRSDGIVAL
                     GGGVVGDLAGFVASTYMRGIHFVQIPTSLTAQVDSSIGGKTGVNTPFAKNMVGTFAQP
                     DGVLIDPLVLETLGKRELIEGMGEVIKYGLIEDPELWALLTGLNGSVESILEHAETLI
                     EHSCQVKRKMVVEDELDNGIRLYLNFGHTIGHAIEATAGYGKVMHGEAVAMGMVQISK
                     VAEEKGLMPAGITQSITEMCQKFGLPVDYENWEVDKLYQALTHDKKARGNTLKLVLVP
                     ELGSATIHPVSLEEMKDYLVK"
     gene            complement(16772..17626)
                     /locus_tag="VU534_000501"
     CDS             complement(16772..17626)
                     /locus_tag="VU534_000501"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HEU1513134.1"
                     /translation="MKLDGYTRLAAVVANPIKHSISPFIHNRAFEATATNGAYVAWEI
                     EASDLVETVANIRRYQMFGINLSMPYKEQVIPYLDKLSDEARLIGAVNTVVNENGNLI
                     GYNTDGKGFFKCLPSFTISGKKMTLLGAGGAAKSILAQAILDGVSQISVFVRSVSMEK
                     TRPYLDKLQEQTGFKVDLCALEYVSELQARIAESDLLVNATSVGMDGQSSPVPENIVL
                     PETLLVADIIYQPFETPFLKWARSQGNPAVNGLGMLLYQAAEAFQLWTGKEMPTEEIW
                     QSLTEKYQ"
     gene            complement(17616..18293)
                     /locus_tag="VU534_000502"
     CDS             complement(17616..18293)
                     /locus_tag="VU534_000502"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HEU1513135.1"
                     /translation="MKLIVSVMPRSLEEAQALDATRYLDADIIEWRADYLPKEAILQV
                     APAIFEKFAGRELVFTLRTRSEGGEIDLSPEEYIHLIKEVAQLYQPDYIDFEYYSYKD
                     VFEEMLDFPNLVLSYHNFQETPENMMEILSELTILNPKLVKVAVMAHTEQDVLDLMNY
                     TRGFKTLNPEQEYVTISMGKVGKVSRITADVTGSSWSFASLDEVSAPGQISLASMKKI
                     REILDEA"
     gene            complement(18290..19453)
                     /locus_tag="VU534_000503"
     CDS             complement(18290..19453)
                     /locus_tag="VU534_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001837533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HEU1513136.1"
                     /translation="MNRIRVSKRVEKKLAKGLVLLEASDLENVNLKDQEVEVQGQEGN
                     FLGTAYLSQQNKGLGWFISKDKVAFNQAFFETLFRKAKEKRNAYYQDDLTTAFRLFNQ
                     EGDGFGGLTVDLYGDYAVFSWYNSYVYQIRQTISEAFRQVFPEVLGAYEKIRFKGLDY
                     ESAHVYGQEAPDFFNVLENGVLYQVFMNDGLMTGIFLDQHEVRGSLVDGLAMGKSLLN
                     MFSYTAAFSVAAAMGGASHTTSVDLAKRSRELSQAHFQANGLSTDEHRFIVMDVFEYF
                     KYAKRKDLTYDVIVLDPPSFARNKKQTFSVAKDYHKLISQSLEILNPGGIIIASTNAA
                     NVSRQKFTEQIDKGFAGRSYQILNKYGLPADFAYNKKDESSNYLKVISMKVSK"
     gene            complement(20140..21774)
                     /locus_tag="VU534_000504"
     CDS             complement(20140..21774)
                     /locus_tag="VU534_000504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001237556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1513137.1"
                     /translation="MRLKVIKKLVDINILYSSQEANLANLRKKQAKNPGKKVNVSARV
                     LSSYIFSSLLMIICFSNIAIHFPFEEIPIYFSSMIAILLVIAFSTSLTAFYNVFYESK
                     DLVSYRPYAFKESEIIIAKGLSVLLPALTGIVPILAYFLVLYIRLAPSLWLGLPLMLL
                     SLTLLFVSVALVMVVAVHFLAQTRVFRKYQSIFSNVMIGIGVLIPLIFIFFLQSTFGS
                     IVDKVRDIPFLLYPLHIFYKIAVEPFSTEALVGLLAWIGLTLFLLYLTKKKVLPRFYD
                     VILLNSEEKVKKERRSKERISTTKKGFFRMVLRYHLTLLGQGTGVITVLFTSAFLPYL
                     MMIGLISKIRDSQIVPDIHPPYWLPLFFIALFIAVVNNNITSLHSIALSLERENVDFL
                     KSLPFDFARYVKVKFWIIYAVQSFLPVLTLLGLSLYLGLPIISMIYLLVVWIIASVIL
                     SCHHYFKDVKNLSTNWSSITDLVNRSNGIVAIVLLFIYSAILMALVIGSIFLVQSLSP
                     ILAISLGVGALIVLLALAIFGYHYYLSRILAEIEKR"
     gene            complement(21755..22504)
                     /locus_tag="VU534_000505"
     CDS             complement(21755..22504)
                     /locus_tag="VU534_000505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU1513138.1"
                     /translation="MIEFQNVSKLYGDKEALSNLNLQIENGEIMGLIGHNGAGKSTTI
                     KSLVSIISPSSGRILVDGQELSENRLAIKRKIGYVADSPDLFLRLTANEFWELIASSY
                     DLSRSDLEASLARLLNVFDFAENRYQVIETLSHGMRQKVFVIGALLSDPDIWVLDEPL
                     TGLDPQAAFDLKQMMKEHAQKGKTVLFSTHVLEVAEQVCDRIAILKKGHLIYCGSVED
                     LRKDYPDQSLESIYLSLAGRKEEVADASQGH"
     gene            22683..24137
                     /locus_tag="VU534_000506"
     CDS             22683..24137
                     /locus_tag="VU534_000506"
                     /EC_number="3.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-amylase"
                     /protein_id="HEU1513139.1"
                     /translation="MQNQTLMQYFEWYLPHDGQHWTRLAENAPHLAHLGISHVWMPPA
                     FKATNEKDVGYGVYDLFDLGEFNQKGTVRTKYGFKEDYLQAIQALKAQGIQPMADVVL
                     NHKAAADHREAFQVIEVDPVDRTVELGEPFTINGWTSFTFDGRQDTYNGFHWHWYHFT
                     GTDYDAKRSKSGIYLIQGDNKGWANEELVDNENGNYDYLMYADLDFKHPEVIQNIYDW
                     ADWFMETTGVAGFRLDAVKHIDSFFMRNFIRDMKEKYGDDFYVFGEFWNPDKEANLDY
                     LEKTEEHFDLVDVRLHQNLFEASQAGANYDLRGIFTDSLVELKPDKAVTFVDNHDTQR
                     GQALESTVEEWFKPAAYALILLRQDGLPCVFYGDYYGISGQYAQEDFKEILDRLLAIR
                     KDLAYGEQNDYFDHANCIGWVRSGAENQSPIAVLISNDQENSKSMFVGQEWTNQTFVD
                     LLGNHQGQVTIDEEGYGQFPVSARSVSVWAVNTI"
     gene            complement(24227..26845)
                     /gene="alaS"
                     /locus_tag="VU534_000507"
     CDS             complement(24227..26845)
                     /gene="alaS"
                     /locus_tag="VU534_000507"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012130635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HEU1513140.1"
                     /translation="MKQLSSAQVRQMWLDFWATKGHSVEPSVSLVPVNDPTLLWINSG
                     VATLKKYFDGTIIPENPRITNAQKAIRTNDIENVGKTARHHTMFEMLGNFSIGDYFRD
                     EAITWAYELLTSPEWFDFPAEKLYMTYYPDDKDSYNRWIEVGVDPSHLIPIEDNFWEI
                     GAGPSGPDTEIFFDRGEAFDPENIGLRLLAEDIENDRYIEIWNIVLSQFNADPAVPRS
                     EYKELPHKNIDTGAGLERLVAVIQGAKTNFETDLFMPIIREVEKLSGKVYDQDGDNMS
                     FKVIADHIRSLSFAIGDGALPGNEGRGYVLRRLLRRASMHGQKLGINEPFLYKLVPTV
                     GKIMESYYPEVLEKRDFIEKIVKSEEESFARTLHSGQHFAQGIVADLKEKGQSVIAGS
                     DVFKLYDTYGFPVELTEEIAEEAGMTVDREGFEAAMKEQQERARASAVKGGSMGMQNE
                     TLQNITVESVFNYNASQLSSKLVAIVADNAEVGAVSEGTASLIFAETSFYAEMGGQVA
                     DYGQILDESGKVVATVTNVQKAPNGQALHTVEVLAPLALNQEYTLAIDSNRRHRVMKN
                     HTATHLLHAALHNILGNHATQAGSLNEVEFLRFDFTHFQAVTAEELRAIEQQVNEKIW
                     EALEVKTVETDIDTAKEMGAMALFGEKYGKEVRVVTIGDYSIELCGGTHVDNTSEIGL
                     FKIVKEEGIGSGTRRILAVTGKEAFEAYREQEDALKAIAATLKAPQVKEVPHKVEGLQ
                     EQLRQLQKENAELKEKAAAAAAGDIFKDVKEVNGHRYIASQVSVSDAGALRTFADNWK
                     QKDYSDLLVLVAAIGDKVNVLVASKTKDLHAGNLVKELAPIIDGRGGGKPDMAMAGGS
                     NQPKIQELLDAVAGKL"
     gene            complement(26867..27352)
                     /locus_tag="VU534_000508"
     CDS             complement(26867..27352)
                     /locus_tag="VU534_000508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000847073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LURP-one-related family protein"
                     /protein_id="HEU1513141.1"
                     /translation="MKTFLVKQKFRLGGERFAIKDDRGEIAYQVEGSFFKIPKTFTIY
                     DAAGEQVSEISKEILTLLPRFEIQLRDGSSFVIRKKLTFWRDKYEFDNLGLRIEGNIW
                     DLNFKLLDDRDQLIAEIKKELFHLTSTYTVTVLEDAYADLVISLCVAIDYVEMLESQS
                     H"
     gene            complement(27627..27866)
                     /locus_tag="VU534_000509"
     CDS             complement(27627..27866)
                     /locus_tag="VU534_000509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000784186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1513142.1"
                     /translation="MKMSTFFKKSFWPTFMIVNQTAILFHLKDGLDRQYLTTESIYWV
                     IGTFIFGNILVAVFSNMKIWDKKKNGSKKKYILKK"
     gene            complement(28119..29189)
                     /locus_tag="VU534_000510"
     CDS             complement(28119..29189)
                     /locus_tag="VU534_000510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEU1513143.1"
                     /translation="MKKIYSFLAGIAAIILVLWGIATHLDSKINSRDSQKLVIYNWGD
                     YIDPELLTQFTEETGIQVQYETFDSNEAMYTKIKQGGTTYDIAIPSEYMINKMKDEDL
                     LVPLDYSKIEGIENIGPEFLNQSFDPGNKFSIPYFWGTLGIVYNETMVDEAPEHWDDL
                     WKPEYKNSIMLFDGAREVLGLGLNSLGYSLNSKDLQQLEETVDKLYKLTPNIKAIVAD
                     EMKGYMIQNNVAIGVTFSGEASQMLEKNENLRYVVPTEASNLWFDNMVIPKTVKNQNS
                     AYAFINFMLKPENALQNAEYVGYSTPNLPAKELLPEETKEDKAFYPDVETMKHLEVYE
                     KFDHKWTGKYSDLFLQFKMYRK"
     gene            complement(29186..29959)
                     /locus_tag="VU534_000511"
     CDS             complement(29186..29959)
                     /locus_tag="VU534_000511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU1513144.1"
                     /translation="MKKFANLYLGLVFLVLYLPIFYLIGYAFNAGDDMNSFTGFSWTH
                     FETMFGDGRLMLILAQTFFLAFLSALIATIIGTFGAIYIYQSRKKYQEAFLSLNNILM
                     VAPDVMIGASFLILFTQLKFSLGFLTVLSSHVAFSIPIVVLMVLPRLKEMNGDMIHAA
                     YDLGASQFQMFKEIMLPYLTPSIITGYFMAFTYSLDDFAVTFFVTGNGFSTLSVEIYS
                     RARKGISLEINALSALVFLFSIILVVGYYFISREKEEQA"
     gene            complement(29956..30762)
                     /locus_tag="VU534_000512"
     CDS             complement(29956..30762)
                     /locus_tag="VU534_000512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU1513145.1"
                     /translation="MKKTSSKLFVVPYMLWIALFVLAPLVLIFGQSFFNIEGQFSLEN
                     YKSYFASQNLTYLKMSFNSVLYAGIVTFVALLISYPTALFLTRLKHRQLWLMLIILPT
                     WINLLLKAYAFIGIFGQNGSINQFLEFIGIGSQQLLFTDFSFIFVASYIELPFMILPI
                     FNVLDDMDNNLINASYDLGATKWETFRHVIFPLSMNGVRSGVQSVFIPSLSLFMLTRL
                     IGGNRVITLGTAIEQNFLTNDNYGMGSTIGVILILTMFITMWVTKERRER"
     gene            complement(30743..31900)
                     /locus_tag="VU534_000513"
     CDS             complement(30743..31900)
                     /locus_tag="VU534_000513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018372333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU1513146.1"
                     /translation="MKKPIIEFKNVSKVFEDSNTKVLKDINFELEEGKFYTLLGASGS
                     GKSTILNIIAGLLDATTGDIMLDGVRINDIPTNKRDVHTVFQSYALFPHMNVFENVAF
                     PLRLRKIDKKEIEQRVAEVLKMVQLEGYEKRSIRKLSGGQRQRVAIARAIINQPRVVL
                     LDEPLSALDLKLRTDMQYELRELQQRLGITFVFVTHDQEEALAMSDWIFVMNDGEIVQ
                     SGTPVDIYDEPINHFVATFIGESNILPGTMIEDYLVEFNGKRFEAVDGGMKPNEPVEV
                     VIRPEDLRITLPEEGKLQVKVDTQLFRGVHYEIIAYDELGNEWMIHSTRKAIVGEEIG
                     LDFEPEDIHIMRLNETEEEFDARIEEYVEIEEQEAGLINAIEEERDEENKL"
     gene            complement(31959..32909)
                     /gene="murB"
                     /locus_tag="VU534_000514"
     CDS             complement(31959..32909)
                     /gene="murB"
                     /locus_tag="VU534_000514"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000116191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HEU1513147.1"
                     /translation="MSVREKMLEILEGIDIRFKEPLHSYSYTKVGGEADYLVFPRNRF
                     ELARVVKFANQENIPWMVLGNASNIIVRDGGIRGFVILCDKLNNVSVDGYTIEAEAGA
                     NLIETTRIALRHSLTGFEFACGIPGSVGGAVFMNAGAYGGEIAHILQSCKVLTKDGEI
                     ETLSAKDLAFGYRHSAIQESGAVVLSVKFALAPGTHQVIKQEMDRLTHLRELKQPLEY
                     PSCGSVFKRPVGHFAGQLISEAGLKGYRIGGVEVSEKHAGFMINVADGTAKDYEDLIQ
                     SVIEKVKEHSGITLEREVRILGESLSVAKMYAGGFTPCKR"
     gene            complement(33021..33773)
                     /locus_tag="VU534_000515"
     CDS             complement(33021..33773)
                     /locus_tag="VU534_000515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000152219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhfC family intramembrane metalloprotease"
                     /protein_id="HEU1513148.1"
                     /translation="MTIHIIITMLLLLAFLIGSIWFAKKKYQINLAVLGLGAVAFFVS
                     SQILEKLVHILILHPQKDGSIALLQDHPLIYIIYGLAMAAFFEETARLVFFKWLEKKR
                     SLEKADALAYGLGHGGLELIFLGLTSLLNLYIVLSAVQTQNPQVMQLLSENMLKTIQS
                     LSVWQIYLLGFERILALGFQLLLTVWVYQAVRQKKWIYLLAAYGLHAFFDLAPSLFQV
                     GWLTNPVLVEVILALELVLVAYGTKEIFCKKS"
     gene            complement(33783..34514)
                     /gene="budA"
                     /locus_tag="VU534_000516"
     CDS             complement(33783..34514)
                     /gene="budA"
                     /locus_tag="VU534_000516"
                     /EC_number="4.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate decarboxylase"
                     /protein_id="HEU1513149.1"
                     /translation="MDKNVQEPVKLFQYNTLGALMAGLYGGTMTVGELLEHGDLGLGT
                     LDSIDGELIVLDGKAYQAKGSGDQPEIVEVSPDALIPYAAVVPHRAEVIFRQRFEMTD
                     KELKERIESYYDGENLFRSIKIRGEFLHMHVRMIPKSTPDTKFADVATHQPEYSRDNV
                     AGTIVGFWTPEIFHGVSVAGYHLHFISDDLTFGGHVMDFVIKEGIIEVGAVDQLDQRF
                     PVQDRQYLFAKFNVDEMKKDIEKAE"
     gene            34656..35927
                     /locus_tag="VU534_000517"
     CDS             34656..35927
                     /locus_tag="VU534_000517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HEU1513150.1"
                     /translation="MKKQSKYKEVVSYLKNGIESGRFPTGSRLPSIRQLSLDFHCSKD
                     TIQRALLELRHEQYLYAKPQSGYYVLEQGQHQDLEIEVTDEHASAYDDFRLCVNETLI
                     GRENYLFNYYDNQEGLEDLRQSIHKLLFEQALYCKANQLVLTSGTQQALFILSQISFP
                     RQAKEILVEQPTYHRMNRLLIAQGLDYQTIERGIDGIDLEELEGHFKTGKIKFFYTIP
                     RFHYPLGHSYSEQDKRSILNLAAKYDVYIVEDDYLGDLDSKKGQTFHYLDTEERVIYI
                     KSFSTSLFPALRITALILPNAIKEAFVAYKNILDYDSNLIMQKALSLYIDSQLFEKNR
                     LARLTNHESYQKQIEERITKTPCPLPHYSLHDGLLLDLRQYPKIASLKHSQLGLDFFE
                     EAYLSTCPYQFAKVSLDNLENVLNYLKAELE"
     gene            complement(35947..36762)
                     /locus_tag="VU534_000518"
     CDS             complement(35947..36762)
                     /locus_tag="VU534_000518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEU1513151.1"
                     /translation="MKSKKWIFVLCNFLASFFLVACQSGSNGSQSAVDAIKQKGKLVV
                     ATSPDYAPFEFQSLVDGKNQVVGADIDMAQAIADELGVKLEISSMSFDNVLTSLQTGK
                     ADLAVAGISATDERKEVFDFSIPYYENKISFLVRKADVEKYKDLTSLESANIAAQKGT
                     VPESMVKEQLPKVQLTSLTNMGEAVNELQAGKIDAVHMDEPVALSYAAKNAGLAVATV
                     SLKMKDGDANAVALRKNSDDLKEVVDKVVQKLKDEGTYQSYLEKAASLTEVEE"
     gene            complement(36919..37572)
                     /gene="phoU"
                     /locus_tag="VU534_000519"
     CDS             complement(36919..37572)
                     /gene="phoU"
                     /locus_tag="VU534_000519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000946475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HEU1513152.1"
                     /translation="MLRSQFEEDLEKLHNQFYAMGQEVLSQINRTVRAFVTHDRDLAK
                     EVIEDDAEVNEYEVKLEKKSFEMIALQQPVSQDLRTVLTVLKAVSDVERMGDHAVAIA
                     QATIRMKGEERIPAVEEEIKKMGREVKSVVEAALDLYLNGSVDDAYRVASMDEQINHY
                     FETIRDLATEEIKKNPEAIVTGRDYFQVISYLERIGDYAKNICEWVVYFETGKIVEL"
     gene            complement(37584..38342)
                     /gene="pstB"
                     /locus_tag="VU534_000520"
     CDS             complement(37584..38342)
                     /gene="pstB"
                     /locus_tag="VU534_000520"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014713134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEU1513153.1"
                     /translation="MTDAILQVSDLSVYYNKKKALNSVSLSFQPKEITALIGPSGSGK
                     STLLKSLNRMGDLNPEVTTTGSVVYNGHNIYSPRTDTVELRKEIGMVFQQPNPFPMTI
                     YENVVYGLRINGIKDKQVLDEAVEKALQGASIWDEVKDRLYDSAIGLSGGQQQRVCVA
                     RVLATSPKIILLDEPTSALDPISAGKIEETLYGLKDKYTMLLVTRSMQQASRISDKTG
                     FFLDGDLIEFNDTKQMFLDPQHKETEDYITGKFG"
     gene            complement(38355..39158)
                     /gene="pstB"
                     /locus_tag="VU534_000521"
     CDS             complement(38355..39158)
                     /gene="pstB"
                     /locus_tag="VU534_000521"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEU1513154.1"
                     /translation="MSTYNWDEKHILTFPEEKVALSTKDVHVYYGKNESIKGIDMQFE
                     RNKITALIGPSGSGKSTYLRSLNRMNDTIDIAKVTGQILYRGIDVNRPEINVYEMRKH
                     IGMVFQRPNPFAKSIYRNITFAHERAGVKDKQVLDEIVETSLRQAALWDQVKDDLHKS
                     ALTLSGGQQQRLCIARAISVKPDILLMDEPASALDPIATMQLEETMFELKKNFTIIIV
                     THNMQQAARASDYTGFFYLGDLIEYDKTATIFQNAKLQSTNDYVSGHFG"
     gene            complement(39169..40053)
                     /gene="pstA"
                     /locus_tag="VU534_000522"
     CDS             complement(39169..40053)
                     /gene="pstA"
                     /locus_tag="VU534_000522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009443446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HEU1513155.1"
                     /translation="MRAKKLDKLATAVLYTIASIIVTILASLILYILVRGLPHISWSF
                     LTGRSSAFQAGGGIGIQLYNSFFLLVITLIISVPLSMGAGIYLAEYAKKGPVTNFVRT
                     CIEILSSLPSVVVGLFGYLIFVVQFEYGFSIISGALALTVFNLPQMTRNVEDSLKHVH
                     HTQREAGLALGISRWETVVHVVIPEALPGIVTGVVLASGRIFGEAAALIYTAGQSAPA
                     LDWSNWNILSVTSPISIFRQAETLAVHIWKVNSEGTIPDGTIVSAGSAAVLLIFILIF
                     NFGARKFGSYLHKKLTAA"
     gene            complement(40043..40960)
                     /gene="pstC"
                     /locus_tag="VU534_000523"
     CDS             complement(40043..40960)
                     /gene="pstC"
                     /locus_tag="VU534_000523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018378778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HEU1513156.1"
                     /translation="MNQEELAKKMLLPSKNSRLEKLGKGLTFACLSLIVILVAMILVF
                     VAQKGLSTFFVNGVNIFDFLLGGTWNPSSKEFGALPMILGSFIVTILSALIATPFAIG
                     AAVFMTEVSPKGAKILQPAIELLVGIPSVVYGFIGLQVVVPFVRSVFGGTGFGILSGI
                     SVLFVMILPTVTFMTTDSLRAVPRYYREASFAMGATRWQTIWRVILKAARSGIFTAVV
                     FGMARAFGEALAIQMVVGNSAVIPTSLTTPAATLTSILTMGIGNTVMGTVNNNVLWSL
                     ALVLLLMSLVFNSVIKLITKERGKKNYAR"
     gene            complement(40960..41838)
                     /gene="pstS"
                     /locus_tag="VU534_000524"
     CDS             complement(40960..41838)
                     /gene="pstS"
                     /locus_tag="VU534_000524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS"
                     /protein_id="HEU1513157.1"
                     /translation="MKKRKKLALSLIAFWLTACLVGCASWIDRGESITAVGSTALQPL
                     VEVAADEFGTIHVGKTVNVQGGGSGTGLSQVQSGAVDIGNSDVFAEEKDGIDASALVD
                     HKVAVAGLALIVNKEVDVDNLTTEQLRQIFIGEVTNWKEVGGKDLPISVINRAAGSGS
                     RATFDTVIMEGQSAMQSQEQDSNGAVKSIVSKSPGAISYLSLTYIDDSVKSMKLNGYD
                     LSPENISSNNWPLWSYEHMYTLGQPNELAAEFLNFVLSDETQEGIVKGLKYIPIKEMK
                     VEKDAAGTVTVLEGRQ"
     gene            complement(42412..43716)
                     /locus_tag="VU534_000525"
     CDS             complement(42412..43716)
                     /locus_tag="VU534_000525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001160253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmF rRNA methyltransferase first C-terminal
                     domain-containing protein"
                     /protein_id="HEU1513158.1"
                     /translation="MQFPEGFVEKYKEILGDEARDFLASFEEEAVSAFRVNPLKEEQL
                     SFSDAITQTPWGHYGKVSGKSPEHATGLVYSQEPAAQMVAQVAQPSPGMKVLDLAAAP
                     GGKSTQLAAYLAGEGLLVSNEISSKRAKILVENMERFGATNVVVTNESADRLVKVFKG
                     YFDLIVLDAPCSGEGMFRKQPDAMDYWSLDYPSQCASLQREILEDAVTMLAEGGHLVY
                     STCTWAPEENEEIVNWLLEEYDFDLLPVEHINGMVAGIDLPETARMYPHQFKGEGQFV
                     AHLQFKGNNPAPKFKASKSNLSREQVALWQEFAQNHLKVNLPGILQIFGDQLYLLPEL
                     LPDLWKLKIARNGLHLGTFKKKRFEPSFALGLALKPSQVEQSVEIGQEAFVKYAAGET
                     VQLAESLPNGWYQVLVKGNGLGFAKVTGNVLKNYFPKGLRFK"
     gene            complement(43717..44490)
                     /locus_tag="VU534_000526"
     CDS             complement(43717..44490)
                     /locus_tag="VU534_000526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HEU1513159.1"
                     /translation="MESKFEFAKELVKKAGQYILDHMQEDLRVETKSSPTDLVTRLDK
                     EVQELLVGEILSRYPEDKICAEEGCLRASVQEGKVWVIDPIDGTNNFVAQQEDFAVMM
                     AYFENGQGQFGLIYDVVKGDCYHGGGEFPVCLNDRSLAPFKTKPLGDFLIAGNSGMLE
                     TNEWGLADLSRAVLGVRVYGSAAISFAKILSGRLLTYLTYLQPWDYAAASILGESLGY
                     RVVTLFGEAPDFQTRQPVMMVPLEMQEEIQSYIYERKRT"
     gene            complement(44480..44758)
                     /locus_tag="VU534_000527"
     CDS             complement(44480..44758)
                     /locus_tag="VU534_000527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0223 family protein"
                     /protein_id="HEU1513160.1"
                     /translation="MNKQYSYPLDLSWSTEELASVLSFFNDVEAAYEGKVEAKKLLDS
                     YKGFKAVVPSKSEEKRLGREFETVSGYSLYRAVQAAKEKGEGKISLGK"
     gene            complement(44758..45159)
                     /locus_tag="VU534_000528"
     CDS             complement(44758..45159)
                     /locus_tag="VU534_000528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007556665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HEU1513161.1"
                     /translation="MITLFLSPSCTSCRKAKAWLEKHKVPFVEHNIMTSPLTRKELQH
                     ILSLTENGTDDIISTRSKIFQKLNIDVESISVSELLHLIEQYPSLLRRPIIIDAKRMQ
                     IGFNEDEIRAFLPRSYRKQELKEARMRAGIS"
     gene            complement(45369..45986)
                     /locus_tag="VU534_000529"
     CDS             complement(45369..45986)
                     /locus_tag="VU534_000529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HEU1513162.1"
                     /translation="MKTKLIFWGSMLFLLSLSILLTIYLAWIFYPMEIQWLNLTNRVY
                     LKPETIQYNFHILMNYLTNPFSQVLQMPDFRSSAAGLHHFAVVKNLFHLVQLVALVTL
                     PSFYVFVNRIVKKDFLSLYRKSLLALVVLPVMIGLGGVLIGFDQFFTLFHQILFVGDD
                     TWLFDPAKDPVIMILPETFFLHAFLLFFALYENFFGYLYLKSRRK"
     gene            complement(45976..46749)
                     /locus_tag="VU534_000530"
     CDS             complement(45976..46749)
                     /locus_tag="VU534_000530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01457 family HAD-type hydrolase"
                     /protein_id="HEU1513163.1"
                     /translation="MKYKGYLIDLDGTIYKGKDRIPAGETFVHELQKRDIPYLFVTNN
                     TTRTPESVKEMLAQNFNIDTPLSTVYTATLATIDYMNDLGLEKTVYVVGEAGLKEAIK
                     AAGYVEDKEKPAYVVVGLDWQVDYEKFATATLAIQKGAHFIGTNPDLNIPTERGLLPG
                     AGSLITLLEVATRVKPVYIGKPNAIIMDKAVEHLGLEREELIMVGDNYLTDIRAGIDN
                     GIPTLLVTTGFTKAEEVAGLPIAPTHVVSSLAEWDFDEN"
     gene            complement(46760..47497)
                     /locus_tag="VU534_000531"
     CDS             complement(46760..47497)
                     /locus_tag="VU534_000531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000524807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-[acyl-carrier-protein] thioesterase"
                     /protein_id="HEU1513164.1"
                     /translation="MGLTYQMKMKIPFDMADMNGHIKLPDVILLSLQVSGMQSIELGV
                     SDKAILEEYNLVWIIVEYDIEVVRLPRFAEEITIETEALSYNRLFCYRRFTIYNEAEQ
                     ELIHMMATFVLMDRDSRKVHVVEPEIVAPYQSDFDKKLIRGPKYESLEEPISKDYHVR
                     FYDLDMNGHVNNSKYLDWIFEVMGADFLTHYIPKKINLKYVKEVRPGGVITSAVERTG
                     LESKHEITSDGVINAQAIITWQEIKKA"
     gene            complement(47502..48632)
                     /locus_tag="VU534_000532"
     CDS             complement(47502..48632)
                     /locus_tag="VU534_000532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-independent coproporphyrinogen III
                     oxidase"
                     /protein_id="HEU1513165.1"
                     /translation="MQKKPTSAYVHIPFCTQICYYCDFSKVFIKNQPVDSYLEHLLEE
                     FRSYDIEKLSTLYIGGGTPTALSAPQLEVLLNGLTKNLDLSVLEELTIEANPGDLDAD
                     KIAVLKNSAVNRVSLGVQTFDDKMLKKIGRSHLEKDIYENIDRLKLAGFDNISIDLIY
                     ALPGQTMEQVKENVAKAIGLDIPHMSLYSLILENHTVFMNRMRRGKLPLPKEELEAEM
                     FEYIIAELERAGFEHYEISNFSKPGFESRHNLMYWDNAEYYGIGAGASGYVNGVRYKN
                     HGPIRHYLSAVEEGNACITEDHLSQKEQMEEEMFLGLRKKSGVSMARFEEKFGQSFAG
                     LYGEIVRDLVQQGLMQIEGDHVRMTKRGLFLGDTVAERFILE"
     gene            complement(48716..49105)
                     /locus_tag="VU534_000533"
     CDS             complement(48716..49105)
                     /locus_tag="VU534_000533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HEU1513166.1"
                     /translation="MGKLSSILLGTVSGAALALFLTSDKGKQVCSQAQDFLDDLREDP
                     EYAKEQVCEKLTEVKEQATDFVLKTKEQVESGEITVDSILAQTKSYAFQATEASKNQL
                     NNLKEQWQEKAEALDDSEEIVIDITEE"
     gene            complement(49121..49504)
                     /locus_tag="VU534_000534"
     CDS             complement(49121..49504)
                     /locus_tag="VU534_000534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HEU1513167.1"
                     /translation="MLEVAYILVALALIVFLVYLIITVQKLGRVIDETEKTIKTLTSD
                     VDVTLHHTNELLAKVNVLADDINVKVATIDPLFSAVADLSLSVSDLNDHARVLSKKAS
                     SAGSKTLKTGASLSALRLASKFFKK"
     gene            complement(49505..50293)
                     /locus_tag="VU534_000535"
     CDS             complement(49505..50293)
                     /locus_tag="VU534_000535"
                     /EC_number="2.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HEU1513168.1"
                     /translation="MLDPIAIQLGPLAIRWYALCIVTGLILAVYLTMKEAPRKKIIPD
                     DILDFILVAFPLAILGARLYYVIFRFDYYSQNLGEIFAIWNGGLAIYGGLITGALVLY
                     IFADRKLINTWDFLDIAAPSVMIAQSLGRWGNFFNQEAYGATVDNLDYLPGFIRDQMY
                     IEGSYRQPTFLYESLWNLLGFALILIFRRKWKSLRRGHITAFYLIWYGFGRMVIEGMR
                     TDSLMFFGFRVSQWLSVVLIGLGIMIVIYQNRKKAPYYITEEEN"
     gene            complement(50286..51221)
                     /locus_tag="VU534_000536"
     CDS             complement(50286..51221)
                     /locus_tag="VU534_000536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr kinase/phosphorylase"
                     /protein_id="HEU1513169.1"
                     /translation="MSVLVKEVIEKLRLDIVYGEPELLEKEINTADITRPGLEMTGYF
                     DYYTPERIQLLGMKEWSYLISMPSNSRYEVLKKMFLPETPAVIVARGLVVPEEMLKAA
                     RECKIAILTSRAATSRLFGELSSYLDSRLAERTSVHGVLMDIYGMGVLIQGDSGIGKS
                     ETGLELVKRGHRLVADDRVDIFAKDEITLWGEPAEILKHLIEIRGVGIIDVMSLYGAS
                     AVKDSSQVQLAVYLENYDTHKTFDRLGNNAEELEVSGVAIPRIRIPVKTGRNISVVIE
                     AAAMNYRAKEMGFDATRLFDERLTSLIARNEVQNA"
     gene            complement(51351..51527)
                     /locus_tag="VU534_000537"
     CDS             complement(51351..51527)
                     /locus_tag="VU534_000537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000048061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HEU1513170.1"
                     /translation="MSKTVVRKNESLDDALRRFKRAVTKAGTLQETRKREFYEKPSVK
                     RKRKSEVARKRKKF"
     gene            complement(51673..52374)
                     /locus_tag="VU534_000538"
     CDS             complement(51673..52374)
                     /locus_tag="VU534_000538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HEU1513171.1"
                     /translation="MKVIKVENQVQGGKVAFEILKEKLANGAQTLGLATGSSPLEFYK
                     EIVESDLDFSNLTSVNLDEYVGLDGDNPQSYRYFMQENLFNQKPFKESFLPRGVKDNA
                     EAEVERYNQILADHPVDLQILGIGRNGHIGFNEPGTPFDSQTHLVELDQSTIEANARF
                     FAKIEDVPTQAISMGIKNILDAKSIILFAYGESKAEAIAGTVSGPVTENLPASSLQNH
                     PDVTIIADAEALSLL"
     gene            52525..53553
                     /gene="queA"
                     /locus_tag="VU534_000539"
     CDS             52525..53553
                     /gene="queA"
                     /locus_tag="VU534_000539"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HEU1513172.1"
                     /translation="MNTADFDFHLPEELIAQTPLEKRDASKLLIVNRETGEMQDKHFH
                     SIIDMLEPGDALVMNDTRVLPARLYGQKVETGGHVELLLLKNTSGDEWEVLAKPAKRL
                     KVGTRISFGDGRLSAVVTEELTHGGRIVRFEYQGIFLEVLESLGEMPLPPYIHEKLDD
                     RERYQTVYAKESGSAAAPTAGLHFTKELLAEIQAKGVHLVYLTLHVGLGTFRPVSVDN
                     LDEHEMHSEFYQLSEEAAATLRSVKKNGGRVIAVGTTSIRTLETIGSKFDGQIQADSG
                     WTNIFIKPGYEWKVVDAFSTNFHLPKSTLVMLVSAFAGRELVLDAYHHSIQEHYRFFS
                     FGDAMFIY"
     gene            complement(54214..54603)
                     /locus_tag="VU534_000540"
     CDS             complement(54214..54603)
                     /locus_tag="VU534_000540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000240828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HEU1513173.1"
                     /translation="MVKRRIRRGTREPEKVVVPEQSSIPSYPVSVTSNQGTDVAVEPA
                     KAVAPTTDWKQENGMWYFYNTDGSMATGWVQVNSSWYYLNSNGSMKVNQWFQVGGKWY
                     YVNTSGELAVNTSIDGYRVNDNGEWVR"
     gene            complement(54657..55349)
                     /locus_tag="VU534_000541"
     CDS             complement(54657..55349)
                     /locus_tag="VU534_000541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HEU1513174.1"
                     /translation="MNTSFVHAADGIQYVRDDTRDKEEGIEYDDADNGDIIVKVATKP
                     KVVTKKISSTRIRYEKDETKDRSENPVTIDGEDGYVTTTRTYDVNPETGYVTEQVTVD
                     RKEATDTVIKVPAKSKVEEVLVPFATKYEADNDLSAGQEQEITLGKNGKTVTTITYNV
                     DGKSGQVTESTLSQKKDSQTRVVKKRTKPQVLVQEIPIETEYLDGPTLDKSQEVEEVG
                     EIGKLLLLQSIL"
BASE COUNT        16560 a        12672 c        10356 g        16145 t
ORIGIN      
        1 tgttttgagc agcctgcggc tagcttccta gtttgctctt tgattttcat tgagtataaa
       61 cttcttttca caaaaaggat atgaacccct ctggtcaaga gtttccccat cctatcttct
      121 attctttatt ttgcttctac acggacacct tgggtatcaa ctctcaagtc atgcagtttt
      181 cctttgaaag gttgcttttc caattctgcc ttaattgttg gcatcttgtc atgagaagcc
      241 agaaccataa ctgtcggccc agcaccagaa aggtaggttg cataggcccc attttctttg
      301 gtcacttgct taatcatcgc aaattctctt accaagtcct gacgatagcg ctcatggaag
      361 aggtctccct cgattgcttg cccagcggtc accatgtctc ctgccaacaa ggcagcaacc
      421 gctacattgg cgatagaact tgcagcaaca gcttccttat aagacaattt tttaggcaag
      481 acactacggc tgtcgcgagt acgtaattca tagtttggaa tgtaagctag aaaatcacac
      541 tctggaaagt ctgctacgat agcagagact tgcccttcaa cagaacttgc aataacgaga
      601 ttaccataaa tggctggagc cacattgtca ggatgccctt caatcttggt cgctaactgc
      661 aatttttcat ggtctgataa gttgagttga cccagttggt tggctagttc aatcccagca
      721 acgataaccg agctggaaga acccaaaccg cgcgccaaag ggacatcact ggtcattttc
      781 aagcgtcttg gttgcaagtc tggtacaatt tgcaaagcga ttttgagcaa gagattacgc
      841 tcgtcatgtg gaatccattt gccaatctgg tgttcaatca gccactcatc tcgttcttcg
      901 cagacctcaa tttgaagata cttggttaca gctacaccga ccgagtcaaa acctggcccg
      961 atattggcac tggttgcagg tacaataatc ttcatcttat tctcctagca ccttgaaggt
     1021 attcaagagg tcgaattctg aaaccttctt caattcagct gagacatttt caagctgggc
     1081 tttattaatc ttgtgtgtga tgataacgac acgcgccttg tcaccctctt tgccatcttg
     1141 aaggatttgc ttaaaggaaa tatcttgagc attgaagatt tcagccaact tcaagacctg
     1201 accttttgag tctagagcca agattgagaa atagtagttt gctttgacat cttcaggatt
     1261 tgccaagacc aagtcacggc tatattcgtt gaagtctttg ccaatagtac catcattcaa
     1321 acgacgaacg atacggacaa tatcagctac aacacttgtt gcagttggtt tttgacccgc
     1381 acctggtccg tagtacatag actcaccaat accgatagat tctacaaaga cagcgttcat
     1441 tacgccattc acactagcaa gtgggtgcgc tttaggtagg aaggttggag tcacttctgc
     1501 agcaatacct gaagaagttt cctcaataga accaaccaat ttcactacgt aaccaagctc
     1561 ttgagctaca gctacgtctt ctggtgtgat attgcggatt cccttgtggg ctacatcatc
     1621 aaaggcaatc ttcatgccaa aggcaaattg gctcaaaata accatcttgt aggctgcatc
     1681 aatcccatct acgtcattcg tcggatcgct ttctgcaaat cctagacgtt gtgcttccgc
     1741 aagagcatca tcgtaaggcc agccttcttc caccatcttg gtcaccatga agttggaagt
     1801 tccgttgact actccaagca cgcgcgtaat tttatcagaa gccaaggaat ttgctaaagt
     1861 acgaagaatt ggaatcccac cagcaactgc tgcttcgtag taaagtgcta ccttgttagc
     1921 ttgagcgatt tctagcaatt ctgcgccatg gacagctaaa aggtccttgt tagcagtaac
     1981 aacgtgtttt ccagcttcca aggcacgagt gataaaggtt ttagcaggct caatacgccc
     2041 catcaattcc actacgatag taatatcctg gtctgataaa atatcatcca cattggttac
     2101 aaagttaaag tcattccctg ctgcaagcaa gcgatttttt tcatcttcat ccttgaccaa
     2161 taccttagca actttgatat ctgaatgtgc tgattgattg atttttcctc cattttcctt
     2221 taggaggaaa ggcacaccac ttgcaacggt accaaatcct agtaaagcaa ttttaactgt
     2281 catctttatc tcctcgaaat tttctaatat agccattata acagaatttt gtgaaaattc
     2341 ctattatagt aaatcactat ttcagtataa aaagaaaaaa cgaatcagac gattcgctct
     2401 tcttaaaatc tgaaaatagc tttccagaaa ggattagccg attttttgca gattgagcac
     2461 tgcatcgtga ctcatcaaga cttgaccata ctcttgtaag actgagcgac tgatatcact
     2521 atcgtctgca aactcgcgca tacgggccaa cagccaagct ggatatgggc ttggatgatt
     2581 ttcaatatcc actaaaatgg tcaaataata gcgctcgttc attttgtaga gttcagaagt
     2641 ttccatttca aaagtcactg tcttggcaaa agctaccaag tcagccaact tagcaaaaga
     2701 aaggatgtag tagatgtaag gttctttctt actctcagct tcttgttcag cctgctcttg
     2761 ctcttcttcc ttgacttcaa cttgctcaag agattgaatg gcttcgatat catccttggt
     2821 tttgtctgcg atgctttttt ccagggtttt gataaattca tctggagaca tttgagccaa
     2881 ttcttccata tctggcaaat ccgataagtc ttcaaaatct agattttggt caatctttga
     2941 cttggtcaca aagacatcta ccttatcagg ttttggagtc acacggaagc tcaacatgcc
     3001 tgtatccaga aagctatcag gcatctctag ctcatccaag atagcataaa agaactcttc
     3061 tgttttttct tgaggaacga gaaagtcagc aatctccatt ccacgatcca tcaaatcctc
     3121 taaagatatc gtgattttta aagttgtatc actaatttgt ttcattttca ttgctagtaa
     3181 cctcatactt tcagttctat ctattatact agatttttac gattttatca aaagaaggct
     3241 cctctatacg gatagatttt ccctagggtc tttctatagg agactccaaa agaaaatttc
     3301 tgcagacaga tagaaaaagc cttcaaaatc ggctaagagc cgactttgaa gaccttatac
     3361 atcagaatac ttataattta aaggttgcta caccgaggat agaacgattt aagtttctga
     3421 gaatttgaag actttgctca aatttcttat aacgagtcac tccgtactct tcaacaagaa
     3481 ggactgtatc tctttccaaa agagatgata catcctgtaa atctacaaaa tgcattcctt
     3541 ttaaagcttc ttgactctgt ttcaatttat ctaagatagc tttatttgag ctaacgatgg
     3601 tcaattcctg tccagtattt ttgtatgaca aaacatctgc taggttagca attgttgtaa
     3661 tctctgttac aaaatcaatt tgatactgag aaaaatcacc tactctattg attgttggat
     3721 taaagagata aactaacaca tttcccatca caaccaaaat cacacaaacc actccaataa
     3781 caactaaacg aagaatcaga tttttcacat ttaagccaag cgctgtttca ccatttgcgt
     3841 tcaattcttt agagttgatg gtttccagtt tttcaatttt cacatttgca taggcatgtt
     3901 taaatttctc aatcaaccca tcaatttttt tctctaacaa gttattggca tctttacttg
     3961 atgtcaaaat tttcacacca acccctgcat cgtcaatcat atagtagacg gtcaattttt
     4021 tccaccaata gtcattcgtt gaatttttca aggttgtttc tgtcgtgtct aattcactgg
     4081 caattttttt caactcactg ggttctacat cattgaaaag ataagctcca ttcaaattac
     4141 catcaatcaa tttcccataa aaatcactat aaccaccaat ttgatgattc aaaatcgttt
     4201 tgtccgactc ttttggagga gtgattttat agataagata agttgaataa cttgttgtat
     4261 ctttgacagt gtttttattc ctaactgctt taattgtaaa tggtacagca atgagagcaa
     4321 ataaagcgat gagagctaaa atatttgctt ttcgcttttt ataaagattt gcaaacaaat
     4381 cagctactga ataatgttca aacatgattt ttttctcctt tgtttagtag atactagttt
     4441 tcctttgtaa gcatttttgc tacaaatata atcacaagaa caattcccca gaattgcatt
     4501 gtaaataaat tgaagaaact ttctgaaaag ctgcttcttg gcataaagaa tagattattc
     4561 aagatgagta gggataaagc aaataggatt gtccttgagc gataggctac ttgcagcatg
     4621 gctataaata atacgccgag taagaaacta agcagaaaga ctccaatcat accatagtcg
     4681 gtatacaact ccatgatata actacttccg ataccatgcc ctttcaagta ttccttgttc
     4741 aagacaagat aggatagatt gtgggcataa ctattactat caatagctag ttccacacta
     4801 ttggttgtat gttcaaaggc ttttcctccg aaaatggctc ccaaactccc ccttgcaaaa
     4861 taatcaagaa caggaccaaa agtaaaatta cggaaatctc ggtaagggag gctactgtta
     4921 aatagaaaac ctcgagccag aacaccaaaa ctagtccctt gtttatagat aaagtcaagt
     4981 aagatatccc agaaacctgt atgggaaact tggacattat cccgtacata attgagtact
     5041 cccatcgcta acatgagaat aggagaacct acaaaaatcg ctaacttttc tttaaaccca
     5101 atccattttc ctttttcagt ttgctcccgc ataaagtaat aaacaaaagc aaataaaata
     5161 cttaaaataa agggatttcg tgtcccaatt gccaaatgaa tagtattagc tgcaataaag
     5221 gagacaagca ctgctgtggc ctgcaatttc tttggcttgg ttgccagata catacacatt
     5281 gcatagaccg taaaggtaga caaaatgtag gtaaaataag gcagtttact ttcaaaattt
     5341 gcatagtagg catagtagga agtctgcaaa cgatacaaga gccgttcaaa taaccgaatg
     5401 aaatagaaag gataagttag aagaaaaact cctagtgata caaagcgtaa ccgcttgata
     5461 taaacctctt ttagagaatt tcctatattt gctactttta ttttcttcct agctatgaag
     5521 taacgagcca gaatgcctcc tgtggtcaag cccagaatcg aaatcatgac aactataaag
     5581 gcaaaacgat aggctattgg atgataggta tccaaagcac catccctaaa ataatcaatg
     5641 gtcggtcttg ataccagaaa tacaaaaatg gttaaataga aaataaaatg gattaagtaa
     5701 tacttgatat cattccaaca agcaattaag ctactaacca acaagaacaa taaagtagaa
     5761 agtaagctaa cattattatt attaaacaga tacacaattc cacttactag cgtcaaggca
     5821 taactgacta tggtcaaact aaataataat cgtttcccat caatcacttg gtcacccccg
     5881 ttctaatgta attttttaga tttttcaata tttttcagta ataagaatcg atataaggaa
     5941 atatttatga atagggccaa agcactaatt cttctcccct tacggaaaat tggattccta
     6001 gaaatagcaa aggcatggcc ttttaaaaaa cgatgaatct gagaataggc ttcaaactgt
     6061 ttatactgat catctagcaa catcttatcc agaataaaga agtgggcata ggccaatctg
     6121 aaaaaagcga cctctttcaa gtcaggatag tttttcacaa cttcattata aaacttttgg
     6181 tagatatcaa tataggctaa atccttctct gcatagggtt tggtcgtaat actatcccct
     6241 ctatggaaat agtaataata gggtttagta ttaaccacat acttcttggc caacttgatt
     6301 aaatcaaaat ggtaataggc atcttcgtaa atcaacccct taggaaagga tagggcagtt
     6361 gcaatctgtc tcttgattag cttattgcaa atcgtcccag gtattttttc acctatgagg
     6421 tattccttta gaaatgtttg agaatcacag acaaaatagt catcctgatt ggctgactgt
     6481 gggctttcat cattagcata gacattcatg acaccacagc tcgaaacatc cgcatcttct
     6541 tgaactaatt gctcatataa gctctgaatc atttctggat ggatataatc atctgagtca
     6601 ataaaaatca gataatcccc gtgagcctgc ttcatcccat catttcgtgc ttgcgacaat
     6661 ccttcgttct ttttatgaag cactgacacc ctgtcatctt gttcagcgat tgaatcacac
     6721 aagcgaccac tttcatctgt tgcaccatca tcaacaagaa taatttccag attttgatag
     6781 gtctgcttct gaatggaagc tatcgatttt tctaggtact gcgccacatt atagactggc
     6841 acaatcacac taattaatgc agtttccatg ctactcctct aatagttttt ctacttgttc
     6901 gatttgtttt gtaattgtaa attgttgaat gaattggcta gcctcatcga catcaaagtt
     6961 tgaggcagaa gtcatgtaat tagtaatcgc ctgagctgcc tcttgattgc tctcaatgat
     7021 ttgtccaaat cgtccttctt gggataattc ctcagcccct ccaacgtccg tagagataaa
     7081 agggagtccc agactcaagg cctccacata cactccagga aaaccttctt gtttagacat
     7141 agacaaaaga actttcgtct gagatagata ctgataagga tttttttgat aaccaaggaa
     7201 atgtacatag tcctcaatcc catactcttt gactcgtttt ttcagttcct cttccatatc
     7261 accagccccg ataaaataga gatgatagtt ttttccctct tggtgtaata atcgtatcac
     7321 ttccactaca cggtcagaac ccttattttc ctcaatccgt ccgatagtac agatactttg
     7381 aggagcaatc tcgatatcga tcttctcttg agatttttct agaatagtct gaaaatcata
     7441 tccattgtag attgtctgta atttagaagt ataatctgga taaacttcct tgatagaatt
     7501 gctggtcttt tttgaaatcc ctacaattgt attcgcagca tccaactggc ttctatgtga
     7561 ttctctttta gagctatcct taagaagttc ttcaatactt ccatgaatcc aagatatctt
     7621 cttgacttct cttcttttag agaacaacag tggtggattc ataatggtaa aagaaacttc
     7681 aacatcataa tcatctttta caagcaaacg acgagtcagt cttggaaaat aaattctcat
     7741 tctccacaaa aaagctcgta accatctggt ttggcgataa tcttgaaggg attttaaaat
     7801 gcgtacatgc tttggaacag attcatatcc cttgtcaaag tgctccattt caagaatatc
     7861 aatatcatac ttttctggat ccagatttga aacaatggtt gatagaatct tctctgcacc
     7921 acctccaaga gaaaaagacc acataaaaaa taagattttt ttcttagcca ccatattctc
     7981 ccttgtattc tgtataagac ttatccatat cagcgatgac agcatcatga tgcggtacct
     8041 gcttgtctgc tggtggaggc gtcatataat ccccaaaagc agttctgaga tagacatcat
     8101 agccgattgg aataggcatc tctgttcctt caaatggcaa gaaaagattg tcttcaaaag
     8161 atgtgattgg gtacttgttt ctcatgtagc caggacctga gcataattct gtaatgccat
     8221 cacaatcagc caaatcatac ttagtcattt ctttctcagc ttttttccag atgcgataac
     8281 ggagagattt tggagtcaaa cccagtaaaa tgcgacttcc ccatttcatg agatcaccat
     8341 gcttttctgg aatagtttgc gcacaaaaga gtgaataaat caaggcccaa cgaacctgtt
     8401 ttttccgctc agctggattt ttcggataat aatccaaagg caaaacatcc aaggccagac
     8461 catgtggcaa atccaaatcc tgctgataag gcttgataca ggtggttttc ttgtcacgaa
     8521 tggtaataaa aagattacga tcaacaaaat ccttgtgact ctttgacaag aaataacgtt
     8581 catctgcata acgaggccat aattctgcta atttctcata atctttacga ggcataaaaa
     8641 agtctaggtc gtcgtcccaa ggaataaatc ccttgtttcg aagggcacca atagcgcctc
     8701 cgccacagag ataacagagc aaatcatgtt ctttacaaaa ggccacaaaa tattcagcca
     8761 tctccagact acgagcctga attgctttta aatcagtcat attgttcatt attctttcta
     8821 tcgtatcgtt tcattatacc acaaacaagg ggtgaaaatc tattgcagac tgtaaaaaat
     8881 caaagcctga ctgctatcca aatagctatc aaactttgat ttttctgtct tatactcttc
     8941 gaaaatctct tcaaaccacg tcagcttcac cttgccgtag gtataggtaa ctgacttcgt
     9001 cagtcttatc tacaacctca aaactgtgtt tttagcagcc tgcggctagc ttcctagttt
     9061 gcactttgat tttcattgag tattatctta tcttaagccc atttgagcga gcttggtttg
     9121 atatttgttt tgatcaacca gcaggcccaa gcccccataa acatcatagg catctaccca
     9181 gtcacccagt tctggaatcg tcaatttttc aataccattt tttgctccat ccaaaacaga
     9241 taaaccgttt gttaggagga aagtataggg tacgttggtt gaggtcatag caaaaacctt
     9301 tccaagagct tcagaaccag tgaaaagttt agtgggatct ttaatttgct ctaaaattgc
     9361 tgttaaaact tgttgctgtc tttttgtacg gccgtaatct gcctcatcat catcacggaa
     9421 acgagcataa ttgagcaggg tcgagccatt catctgctgt tttccgactt taatggtttg
     9481 ggttggagac tcagtctcgg tagcgtataa atcatctccg actgtagctt ctgttagggg
     9541 acgcccattc aatgttgaaa attgagcatc aatcgtcacc ccatcaggga aaagcgtgtc
     9601 aatcgctgtg gcaaaggcct ggaaatcaac caaggcgtag tacttaatgt ccaagtcaaa
     9661 attatctttc aagacttggc gaaccatttc tgcccctttt tgcccctctt gttctcctaa
     9721 ctcgtaggct acgtttaact tgttatctgt ctgttttcta ccattaatca cttgactata
     9781 accatctata tagaccaaat tatcacgcat gaaactgact agcttcattt tcttatctga
     9841 gcccccgaca tttaatacca taatagagtc agttcgtgtc tcaacactgt tctggccgat
     9901 tcgaccatca gtacccatga ttaaaatatt aactccatct ctagtgtcct gaccattaaa
     9961 gacttctact tgagctgccc gggcatcagc agttttcttt gcgctagcat cttggtaacc
    10021 acgcaaaaac atgaatacca tggccaaagc cacacagacc aaaagtgaaa aaatcaccat
    10081 aaaaattcgt ttaagacgga gcttccgtct tttctttttt ggagggaaag agagtgcttg
    10141 tgatttggat tgtgagcgac tccggttcgc atagcttggt aagtcaacct gctcttctct
    10201 ttcttgttcc aagctagagc tactatttcc cctagcaaga gttagctttt cttgcaaata
    10261 ggcaaactca tttttttctc tctcattgag atagtgaata ttttttagca aataatcata
    10321 acgcaactgc tcatgatgac ttaagggatt ttctttactc atcttctctc ctttccatgg
    10381 tctgatattg gataaatagg ataggcaccc agaattttat actggattcc aatcgcttct
    10441 aattcttttt gggcaaagtg gaccaagtcc ttatcggtat aatccacatc gataatgaaa
    10501 aagtattcac ccagtgctgt cttgagtgga caactttcaa tttttgtcaa gtcaattcct
    10561 cgccaagcaa aggtcgacag ggccttataa agtgcacctg gaaggttgtc aggtaatgtc
    10621 aaggccaaac tcatcttttc agtttgtgct tgcaagggaa tactaggctt ttcagctcct
    10681 agaacccaga aacgtgtgaa attggcttcc atttcctgaa tatcctcggc aatcagttcc
    10741 aatccatatt cttcagcaga acttctaggt gcaactgctg caaagggctg gtctggatgt
    10801 tcggaaataa aacgggccgc ataagctgta ctagctgtta cctcgatttg agcctctgga
    10861 tattgttcat cgatgaattt ctttccttga gccaaggcct gtggatgtga aaaaatcttt
    10921 tcaatcttag tatggcctgg aaccaccatc aactgctgat gaataggctg aacgatttct
    10981 gctactgctt ggatgtgagc ctgatgaaaa agatagtcca aggtttcatg aacactaccc
    11041 tcaatagaat tttcaactgg caccacagaa tagttcacta atccttgctc ataagccttg
    11101 atgacatctg taatgttggc aaaagcctgc aattcctcat gaggaaaagc tgtctgcaca
    11161 acgtggtgtg aaaatgatcc cttgggacct agataagcaa ttttcatctt agttcctcta
    11221 taatttcctc tgggcttagc ttggtcacat ccaaaacccg actagccact tcctcatacc
    11281 aagcctgtct ttcttggaaa atagctacta gttcttcctt gctattattt agaaaaagcg
    11341 gtcgctgatt gtccttatca gctgcgatac gttggtagag ggtttcaaaa tctgctctca
    11401 ggtagatgtt atctgtatta gtcttgagta agtcacgatt tctctgagaa ataaccactc
    11461 ctcctccagt tgacacgact tggtctgttt gtagtaaatc agctaggact tctgattcta
    11521 cctgacgaaa ggctgtttct cccttttcag cgaaaaaatt cgcaatggac atacctaggc
    11581 gattctcaat cagagcatcc atatcaaggt aattagggtc caagcctctt gcaatagtcg
    11641 attttccagc ccccataaac cctaataaca ccttagccat gaatcaagct ctccaaatca
    11701 tcaaagaaac taggatagct ggtattgatg gcttctgcac ggtcaagctc cacctctcca
    11761 tctgcaacca agagggctgc gatagctgtc atcatgccga tacggtggtc accaaacgta
    11821 ttgactctag caccgtgaag agctgatttt cctttgataa tcatcccatc tgccgtagga
    11881 gtaatatctg ctcccatact atttaaggcg tctgccacaa cctgaatacg gtctgtttcc
    11941 ttgaccttga gctcctcagc atccttgata actgttacac cttgggcttg ggtcgcaagc
    12001 agggcaataa tgggcaattc atcaatcaat cgtggaatca aagcgccacc aatctctgtt
    12061 cctttcaagt cagaagactc aacaatcaag gtagcagatt tagcgactgg atcgatttca
    12121 gttatttcca attttccacc catggcacga atgacatcaa taataccggt gcgagtttcg
    12181 ttgatcccca cattctgcag cactagacga gaatttggag caatcaaacc tgcgactaac
    12241 caaaaggctg cactggaaat atctcctggt acgaccacct tctgtcctgt caatttttgt
    12301 ggcccctgga ctgtgatttt cttaccatcc acacttaaat gaccaccaaa ttgtttcaac
    12361 atatcttcag tatgattacg ggtgtactct ttttcgataa taactgactc ccccttagct
    12421 tgtaaggctg caaacatcaa ggctgacttg acttgggcag aggcaattgg caactcataa
    12481 tgaataggtc ttaggttttt cgtccctttt aagcgaaggg gaggcaagtc tcgttcagtt
    12541 tgccctgaaa tgctgacgcc catttttttc agtggaaggg tcacacggtc cataggacgt
    12601 ttggaaagac tatcatctcc aaacatctct acttcgaaat ctgcaccagc aaggacacct
    12661 gaaatcaggc gaatcgaggt gccagaattt cccatattaa gggcattttg tggcgctttt
    12721 aagccagcca tgcctacacc ttgaatggta ataaccccat ctttatcctc aatttcaaca
    12781 ccaaggtcac gaaaaacctg catggtcgaa agaacgtctt cacctcgcag aatatcataa
    12841 accttggtct caccctcagc caaacttcca aagataatgg aacggtggct gatagacttg
    12901 tcacctggga cgcggatact accatgtaaa tggcgaatgt ttgtttttag tttcatactg
    12961 gacctcatac ttgcaatact tttacctatt ttatcataaa aagccagaaa ttccttaaaa
    13021 attcctgact ttaggatcgt tcttttctta tttcagcaat tctgaaactg gttcaaaaac
    13081 aattttttca atatcagaaa ggtaaatggc caattgttgt tgcttggtaa agaattctga
    13141 caagaggcta tttccttgaa tctgtttacc aaagccttcc atcttagctt ggaaggacgc
    13201 atctggcatt tgacctgtct gtgctagttt ttgaatttcc tcttgaaagg caagataatc
    13261 tgtaaagatt ttgcttgcct cagcatctgc tgcaatcgca tctttagctg ctttaacagc
    13321 cttgtattct ggtaatccgc gtagaccgcg actgagttcg tttgcactat cgtaaatatt
    13381 tgacatgttc ttctccttat ttgatgacga ctgtatagtc agtattttct gttatgagat
    13441 gctcagctct ttccaagtct tgagcatttt taaatgaaat ttgtaggatt ccgtgaatat
    13501 cctcacgatt ttcctcgttg atgtggatat taaccaagga agttccacgt agcagttcca
    13561 aaatccgcag gatgacatct tcttcatcag gaacgtcaac atagaggtcg taagagctat
    13621 ccacaccacc acgcttatgg atttccatgg tctggcgttg ttcacgcgct tggttaaaaa
    13681 agttccaaat ttgctcttca tctcccttac taatggcctg accaatcgct tccaaacgtt
    13741 ccttgaaatc ctcaattcta tccagaatga tctcgctatt ggacaagaga atggaggtcc
    13801 acattcctgg ctcgctttcc gcaattcggg tcatatctcg aaaaccacct gccgcaaagc
    13861 gccttgccat ctcatgctct tgagcataga ccgcagtctg ctccatgaga ctagaagcca
    13921 aaatatgagg aaaatggcta atctgagaag tgacacgatc atgctccttg gcatcaatct
    13981 cgataaaacg agcatgaaga cctgaaagca gatccttcat ttccttaagc gtgtcctgac
    14041 ttgtcaggct tgaaggtgta aagatataat aggcattttc aaaaagattg acatctgccg
    14101 aagcagcccc tgtcttgtga ctaccagcca tgggatgggc cccgacaaag cgaacagact
    14161 tgccagccaa atactgctcc gccgcatcca caatggttga cttggtcgaa ccagcatctg
    14221 aaataataac gccttctcgc aaatccaaat tggccaactc cttaatgaaa gcaatagttt
    14281 gtttgattgg caagctgagg ataatgacat ctgccaaagg agcaaaacta gcaaaatcat
    14341 ccgttgcacg gtcaatcata ccttctttca aggcgatatc tctcgaagct tgactacgat
    14401 tataacctaa aatttcataa tctggatgat cgcgtttgat accaagtgcc atagaggctc
    14461 caatcaaccc aagacctgcg atatagattg tttttgccat aggaactcct taatagttct
    14521 ttgtatagtc tcggtgtttg gctaccgctt cttttagttc ctcaagatta tctgatgaga
    14581 atttttcgag gatttcttgc gccagaactg ttgctacaac tgcttccatg accattcctg
    14641 cagctggaag agcagtcgga tcacttctct ccacggttgc cttgtaaggt tcgtgggttt
    14701 cgatatccac actcataaga ggtttataaa gagtaggaat gggtttcatg accccacgaa
    14761 caacgatggg ttgcccatta gtcataccac cttcaaaacc acctagatta ttggtacggc
    14821 gagtataacc gtcttcttta gaccagagaa tttcatccat aacttggctg cctttacgat
    14881 aaccagcctc aaagccaaga ccaaattcca cccctttaaa ggcattgata gagacaacag
    14941 cttgagccaa tcttgcatcc aattttctat cccattggac ataggaacca agaccaactg
    15001 gaacgcctcc gacgactgtc tccacaaccc caccgatggt atcaccatca cgtttgattt
    15061 ggtcaatata gtccttgatt tcctgttctc gttcttggtt gacaatagaa acttcagact
    15121 gggcagctct ttgcttaatt tcagcgactg tcagattttc aggaacatcg atttccttgc
    15181 caccaaagac cacgacatgg ttggcaatct ccatatccag ctcagccaag aggcgtttgg
    15241 ctactgcacc aactgccacc cgcatggtgg tttcacgagc tgatgaacgc tccaaagaat
    15301 ttcgcaaatc atcaaaacgg tacttaatcc ccccaaccaa atcggcatga cctgggcgag
    15361 gatgagtaat tttccgcttg cttttaaggc ggtcttcaat gtcctccgca gacatgatgt
    15421 ccagccattt ctggtggtcc ttattgatga catccatagt aataggcgcc cctgtcgtct
    15481 tcccgtggcg aacgcccgaa gtaaagacaa cctggtcatt ctcaatcttc atacgaccac
    15541 cacgaccgta gccaccctga cggcgtctaa ggtcctcatt gatatcctca gctgtcaatg
    15601 gaagtccagc tggaattccc tcaataatag ctgttagacg ggggccgtgt gattctcctg
    15661 cagttaaata tctcatacac tctccttatt ttaccaagta gtctttcatc tcttccagag
    15721 aaactgggtg aatggtcgct gaaccaagct ctggcaccaa gaccaatttc aaggtgttac
    15781 cacgcgcttt cttgtcatga gtaagagcct gataaagctt gtcaacttcc caattttcat
    15841 agtcaacagg caaaccgaat ttctgacaca tctctgtgat agattgggta atgccagctg
    15901 gcatgaggcc tttttcctca gcaaccttgg aaatctgtac cattcccatg gcaacagcct
    15961 ctccatgcat gaccttgcca taaccggcag tcgcttcgat ggcatggcca atagtgtggc
    16021 caaaattgag gtaaagacga ataccattgt ccaactcatc ttcaaccacc atcttgcgct
    16081 tcacctgaca agaatgttca atcaaggtct ctgcatgttc caaaatactc tcaacagaac
    16141 cattcagtcc cgtcaagaga gcccacagtt ctggatcctc aatcaagcca tacttgataa
    16201 cttcacccat cccttcaatc aactctcttt ttccgagggt ttcaagaaca agtggatcaa
    16261 tcagaacccc atctggttgg gcaaaggtcc ccaccatatt tttagcaaat ggtgtattaa
    16321 cgcctgtctt tccaccgata gaagaatcaa cctgagctgt caaactagtc ggaatctgaa
    16381 caaagtgaat accccgcata taggtagagg ctacaaatcc agccaggtcc ccaacaacgc
    16441 caccaccaag agcaacgatt ccatcgctac gagtcagacc ttgcttgact agaaattcat
    16501 agactttctg aacagtagtt aaattctttc tttcttcacc ttctaagaaa tcaaaaacag
    16561 ctacctgaaa accagcatct tctaggctga gcttgacctt ctctgcatag agagaggcta
    16621 catggttatc tgtcacaatg actacctttt gcggttgcca gagttctcgc aaccactgac
    16681 cagcctgggc catacaacct ttttcaatct gaatatcata aggatggtga ggaatatcga
    16741 ttctgatttt cataggagag tctccctttc tttattggta tttttctgtt aaagactgcc
    16801 aaatctcttc tgtcggcatt tccttgcctg tccacagttg aaaagcttct gcagcttgat
    16861 agagtaacat tcccagacca ttgactgctg gattgccctg acttctagcc catttcaaaa
    16921 acggtgtttc aaagggttgg tatatgatat ctgcaactaa aagagtttct ggtaagacta
    16981 tgttttcagg aacaggagag gattggccat ccatgcccac actggtggca ttaactagca
    17041 aatccgactc ggcaatcctt gcttgcagtt cagaaacata ttctaaagca cacaaatcca
    17101 ctttaaaacc tgtctgctcc tgtaacttgt ctaggtaagg tcttgttttt tccatagaaa
    17161 cggaacgaac aaagaccgaa atctgactga cgccatccaa aatagcctgt gccaagattg
    17221 atttagccgc accacctgca cccagcaggg tcatcttttt acctgaaatt gtaaaagaag
    17281 gcaagcactt aaaaaatccc ttgccatctg tattatatcc aattaaattg ccattctcat
    17341 tgacaaccgt attaaccgca ccaatcaagc gcgcttcatc gctcagctta tccaaataag
    17401 gaatcacctg ctccttatag ggcatggaca gattgatgcc aaacatctgg tagcgacgaa
    17461 tattggccac tgtttctacc aagtcactcg cttcaatctc ccaagccaca taagcaccgt
    17521 tggtagctgt cgcctcaaag gctctattgt ggatgaaggg agaaatagaa tgcttaatag
    17581 gattggcaac aactgcagct aaacgtgtat agccatcaag cttcatccaa aatctccctg
    17641 atttttttca tgctagctag agaaatctgc ccaggggcac taacctcatc cagactggca
    17701 aaagaccaac tcgaaccagt cacatccgca gtgatacgag agaccttgcc caccttaccc
    17761 atagaaatgg tcacatattc ctgttcagga ttgagggttt taaagcctcg tgtatagttc
    17821 atcaagtcta agacatcctg ctccgtgtga gccatcaccg caaccttaac aagttttgga
    17881 tttaggatcg tcaactctga caagatttcc atcatgttct caggtgtttc ttggaaatta
    17941 tggtaactca aaacaagatt tgggaagtcc agcatttcct caaaaacatc cttgtagcta
    18001 tagtactcaa aatcaatata gtctggttga tagagttgcg caacttcctt gattagatgg
    18061 atatactctt ctggagaaag gtcgatttct ccaccttcgg agcgagttcg tagcgtgaaa
    18121 accaactcac ggcctgcgaa tttttcaaaa atggctggag ctacctgcaa aatcgcttct
    18181 ttaggcagat agtcggcacg ccattcaatg atgtcggcat ccaggtacct cgtggcatcc
    18241 agagcctgag cctcctctaa acttcttggc attactgaaa cgattaattt catttactaa
    18301 ccttcatact aatcaccttg aggtaattac tactttcatc ttttttatta taggcaaaat
    18361 ctgctggaag accatatttg tttaaaatct ggtaacttct tcctgcaaaa cctttatcaa
    18421 tttgttctgt aaatttctga cgggaaacat tggcagcatt ggtactggca atgataatcc
    18481 ctcccggatt taaaatctca agactctggg aaatcaactt gtgataatcc ttggccacag
    18541 agaaagtttg ttttttattc cgagcaaagc taggcggatc taggacaatc acatcgtagg
    18601 tcaagtcttt gcgtttggca tatttgaaat actcaaagac atccatgact ataaaacgat
    18661 gctcgtctgt gctgagccca tttgcctgaa aatgcgcttg agacaattct cgtgaacgtt
    18721 tggctagatc aacagaagtt gtatggctag ctcctcccat ggccgcagct actgaaaaag
    18781 ccgctgtgta ggaaaacata ttgagtaagg atttacccat agccaagccg tcaactaaac
    18841 taccgcgaac ctcatgctgg tctaggaaaa ttcctgtcat caagccatca ttcataaaga
    18901 cttgatacag gacaccattt tctaaaacat tgaaaaagtc aggtgcttct tgaccataaa
    18961 catgggcaga ttcatagtcc aaacccttaa agcggatttt ctcataagct cctaaaacct
    19021 cagggaaaac ctgtctaaag gcttctgata tagtctgacg aatctgataa acataagagt
    19081 tataccaaga aaagacggcg tagtcgccat aaaggtccac tgtcagaccc ccaaagccat
    19141 ctccctcttg attaaagaga cgaaaggcag ttgtcaaatc atcttgatag taggcgtttc
    19201 tcttttcttt ggcttttcta aacaacgttt caaagaaagc ttgattgaag gccaccttgt
    19261 ctttgctgat aaaccagccc aagcccttgt tttgctgaga aaggtaggca gtcccaagaa
    19321 agtttccttc ctgaccctgc acctctactt cctgatcctt aagattgaca ttctcaagat
    19381 cactggcttc tagtaaaact agccccttag caagcttctt ttcaaccctt ttgctgactc
    19441 ttattctatt cataactacc attatatcaa acttttagac aattctcaaa aaagaaacta
    19501 cccttgcttt tttactcttc ttttaaaaaa tggtatacta gacttcctgc aaaactagga
    19561 agtaaatgtg taagaatcac agtaaaaaat gctcttccgt cttggaggag catttctttt
    19621 tatcaacgaa aatcaaatag caaactatga aactagcctc aggttaactg tgagattata
    19681 ggtagagagg ttgtatcagc aatatgtgtc tgtcaaattt agtgacaaag gtagtagaag
    19741 aaagataaag aaataaatca gcttcagtag gtatctggaa aatttgattt tatagagaag
    19801 ccttttgtta caaactcaat atactatcaa taaataatat tatagaagca acaataatta
    19861 taatttcacc tatctgcatc attctatttc gaactctaaa tatatgttct atcaaaaata
    19921 cttggaacac acacattata ggaattaacg tttttgaaat tgaaaaatat ccaaataaat
    19981 aaactataaa caacaaaaat agaactatgt tatatttctt attcaaaaca ttcctcccta
    20041 tatatttttg attaccaatc ttaatcattt acaactacat tctaacaaac tataaaagcg
    20101 tttgtcgaat tgaatttatc aagcaagcga ccaaccagtt catctttttt ctatttctgc
    20161 caatatgcgt gacaggtaat aatgatagcc aaaaatagca agagcaagca agacgataag
    20221 agctcctact cccaagctga tggcaaggat aggggagaga gactgaacca agaatatgct
    20281 cccaattaca agggccatca ggattgcact ataaataaac aataaaacta tggcgactat
    20341 gccatttgaa cgattcacca ggtccgtaat gctactccaa ttggttgaca gatttttaac
    20401 gtccttaaag taatggtggc aagaaaggat gacactggca atgatccaga ctacaagaag
    20461 gtaaatcatc gaaatgatgg gcaagcctag atatagagaa agaccaagca aagtcagaac
    20521 tggtaaaaag gactggacag catatataat ccaaaatttc actttcacat aacgagcaaa
    20581 gtcaaagggt aaactcttaa gaaaatcaac attttccctc tccaaggaca aggcaattga
    20641 atgcaggctg gtgatattgt tattgacaac tgctataaag agagctataa aaaacaaggg
    20701 taaccagtat ggaggatgaa tgtctggaac tatctgagaa tctcggattt tggaaatcag
    20761 accgatcatc atgagataag gaaggaaagc acttgtaaaa agcactgtaa tcacgccagt
    20821 cccctgtccc aagagggtga ggtggtagcg taaaaccatg cgaaaaaatc cctttttagt
    20881 ggttgaaatt ctctccttgc tgcgacgttc ttttttgacc ttctcctcac tattaagcag
    20941 gatcacgtca taaaaacgag gaaggacctt ctttttggtc agataaagca ggaagagagt
    21001 tagtcctatc caagcgagca gacccactaa ggcttctgtc gaaaaaggct ccactgctat
    21061 tttgtaaaag atatgaagag gataaaggag aaatggaatg tctctaactt tgtcaacaat
    21121 acttccaaaa gtcgactgaa gaaagaagat aaatattaaa ggtatgagaa ctcctatccc
    21181 aatcatcaca ttcgaaaaaa tagactgata ctttctgaag accctagttt gagccaagaa
    21241 atgcactgcc actaccatca ctagagccac agagacaaat aataaggtca aggacagtag
    21301 catcaaaggc aaacccagcc atagagaagg agctagccta atgtagagga ccagaaaata
    21361 agctaggatt ggtacaattc cagttagagc tggcaaaagg acagacagtc ctttagcaat
    21421 tataatctct gattctttaa aggcataggg cctatacgat accaaatcct tactctcata
    21481 aaagacattg taaaaggccg ttaaagaagt tgaaaaggca atcactagta aaatagcaat
    21541 catcgagcta aaataaatag gtatttcctc aaaaggaaaa tgaatggcta tattactaaa
    21601 acagatgatc atcaagagac tggaaaaaat gtaagaactt aagactctag cggaaacatt
    21661 tacttttttc ccaggattct tagcctgctt ctttcgtaga ttagccagat tagcttcttg
    21721 agatgaataa aggatattga tatcaactaa ttttttaatg accttgagac gcatccgcaa
    21781 cctcctcttt tctaccagca agactaaggt agatactttc caaagactgg tctgggtaat
    21841 cttttctcaa gtcctctaca ctaccacaat aaatcaaatg cccctttttc aaaatggcaa
    21901 tccgatcaca gacttgctct gccacctcta ggacatgagt tgaaaacaag actgtcttcc
    21961 ctttttgtgc atgttccttc atcatctgtt tcaaatcaaa ggcagcctgg ggatccaaac
    22021 cagtcaaggg ttcatccaag acccaaatat cgggatcaga caagagtgct ccgatgacaa
    22081 agactttctg acgcattccg tgagaaagag tttcaataac ctgatagcga ttttcagcaa
    22141 aatcaaaaac gttcaatagc ctagctagac tagcctccaa gtcagatcta ctcagatcat
    22201 aggatgaggc gatcaattcc caaaattcat tggccgttaa gcgtaaaaat aagtcaggcg
    22261 agtctgctac gtagccaatc tttcgtttaa tagccaagcg attttccgat aactcctgac
    22321 cgtctaccaa aatacgacca ctgctgggtg aaatgatact gactagggat tttatagtgg
    22381 tcgattttcc agccccatta tgaccaatca agcccataat ctctccattt tcaatctgca
    22441 aattgagatt actcaaggcc tctttatcac catacaactt actaacattt tgaaattcaa
    22501 tcatgggaca actcctatct ttatctgtat tatatatcgc tatactagca ctttgataca
    22561 aaaaaatcaa tactttattt taagtagtta aaatagtttc cttctatctt acgcaaacgt
    22621 ttgcgctaat agatacttta tgatagaata aagaacaaga ttgacaagta agaggaaaca
    22681 ttatgcaaaa tcaaacactc atgcaatact ttgaatggta tctgccccac gacggtcaac
    22741 actggacgcg tctggctgaa aatgctccac acctagctca tctggggatc agtcacgtct
    22801 ggatgccacc agccttcaag gcaaccaacg aaaaagatgt cggctatggg gtctatgact
    22861 tatttgactt aggagagttc aaccaaaaag ggactgtccg caccaagtat ggtttcaaag
    22921 aagactatct tcaagccatt caagccctta aagcacaggg aattcaacct atggccgatg
    22981 tagttctcaa ccacaaggct gctgccgatc acagggaagc ctttcaggtt atcgaagttg
    23041 atcctgtaga ccgtacagtt gaacttggag aacccttcac catcaatggc tggactagtt
    23101 ttaccttcga tggtcgccaa gatacctata atggcttcca ctggcattgg taccacttca
    23161 ccggtacaga ctacgatgcc aaacgcagta aatctgggat ttatctgatc caaggggaca
    23221 acaagggctg ggccaacgag gaattggtcg ataacgaaaa cggaaactac gactacctca
    23281 tgtatgccga cctagacttt aaacatcctg aagtcatcca aaacatctat gactgggctg
    23341 attggttcat ggaaacgact ggtgtagctg gtttccgttt ggatgccgtt aagcatattg
    23401 actctttctt tatgcgcaac ttcatccgcg atatgaagga aaaatacggt gacgatttct
    23461 atgtttttgg tgaattttgg aacccagaca aggaagccaa tctggactat ctcgaaaaaa
    23521 cggaagaaca ctttgacctt gtcgatgttc gtctccacca gaatctcttt gaagccagtc
    23581 aagctggcgc aaactatgac cttcgtggca ttttcacaga tagcctggtt gaactcaagc
    23641 ctgacaaggc tgtgactttt gtcgacaacc acgataccca acgaggacaa gcccttgagt
    23701 ctaccgttga agaatggttc aagccagcag cctatgccct cattttgtta cgccaagacg
    23761 gccttccatg tgtcttttac ggagactact atgggatttc agggcagtat gctcaagaag
    23821 atttcaaaga aatccttgac cgcctcctag ccatccgaaa agatttggcc tatggagaac
    23881 aaaatgacta ctttgaccat gctaactgta tcggttgggt acgttcaggt gctgaaaatc
    23941 aatccccaat cgcagtcctt atctcaaatg accaagaaaa cagcaagtca atgtttgtcg
    24001 gtcaagaatg gactaatcaa acctttgtag atttacttgg taaccaccaa ggtcaagtta
    24061 caattgatga ggaaggttat ggacaattcc ctgtctcagc tagatccgta agtgtctggg
    24121 cagtcaatac catctaatag ctcataataa ccaagctagg tccaagcgga tttggctttt
    24181 ttgtattcac aaaaagacct acccaaatgg atagatcttt acttgattac aatttacctg
    24241 ctactgcatc caacaattct tggatcttag gttggttgct tcctcctgcc atggccatat
    24301 ctggtttacc accaccacgt ccatcgatga ttggtgctaa ttctttgaca aggtttcctg
    24361 catgaaggtc ttttgtcttg cttgctacaa ggacattgac tttgtcaccg atagcggcaa
    24421 ctaggacaag aagatcagag tagtcttttt gtttccagtt atctgcaaaa gtacgaaggg
    24481 caccggcatc ggatacagac acttgactag caatgtaacg atgaccgttg acttccttaa
    24541 catctttgaa gatatcgcct gcggctgcag ctgcggcttt ttctttcaac tcagcatttt
    24601 ctttttgaag ttgacgaagt tgttcttgaa gtccttctac cttgtgaggt acttccttga
    24661 cttgaggtgc tttcaaggtt gctgcgatag ctttaagagc atcctcttgt tcacgatagg
    24721 cttcaaaggc ttccttacca gtcactgcca agatacggcg agttcctgaa ccgattcctt
    24781 cttctttgac aattttgaag agaccaatct cagaagtgtt gtcaacatga gtaccaccac
    24841 aaagttcaat agagtagtca ccgatagtca cgacacgaac ttccttgccg tatttctcac
    24901 caaagagggc catagctccc atttctttag cagtgtcaat atccgtttca actgtcttca
    24961 cttcaagtgc ttcccaaatt ttctcgttaa cttgctgttc aatcgcacga agttcctcag
    25021 cagttactgc ttggaagtgg gtaaagtcaa agcgaaggaa ttcaacttcg ttaagagatc
    25081 ctgcctgtgt tgcgtggttt ccaaggatat tgtgaagggc agcgtgaagc aaatgagtcg
    25141 cagtgtggtt tttcatgaca cggtgacggc gattgctatc aattgccaag gtatattctt
    25201 ggttcaaggc aagcggtgca aggacttcaa ctgtatgaag ggcttgacca tttggggctt
    25261 tctgaacatt ggtcacagta gccacaacct tacctgactc atccaagatt tgtccgtagt
    25321 cagctacctg tccacccatt tcagcataaa atgacgtttc cgcaaagata agagaggcag
    25381 ttccttctga aacagctcct acttctgcat tgtcagcaac gatagctacc aatttagaag
    25441 acaattggct agcattgtag ttgaagacac tttctacagt gatgttttga agagtttcat
    25501 tttgcatacc cattgagcca cccttgacag ctgacgcacg cgcgcgttct tgctgttctt
    25561 tcatggctgc ttcaaaacct tcacggtcta cagtcatacc agcttcttca gcgatttctt
    25621 cagtcaattc aactgggaac ccataagtat catagagttt gaagacatct gaaccagcga
    25681 taacagattg acctttttct ttcaagtctg ctacaatgcc ttgggcaaag tgttgacctg
    25741 agtgaagggt acgggcaaat gattcttctt cgctcttaac gattttctca ataaagtcac
    25801 gtttctcaag cacttctggg tagtagcttt ccatgatttt tccaacagtt ggaaccaatt
    25861 tgtaaaggaa aggctcgttg atacccaatt tttgaccatg catagaagca cgacggagaa
    25921 gacgacgaag aacataacca cgaccttcat ttcctggaag ggcaccatca ccgatagcaa
    25981 atgaaagaga acgaatgtgg tctgcgataa ccttgaagct catgttgtcg ccatcttggt
    26041 cataaacctt accagacaat ttctcgactt cacggataat cggcatgaag aggtccgttt
    26101 caaagttggt cttagcccct tggataacgg ccaccaaacg ctccaaacca gcgcccgtat
    26161 caatgttctt atgtggcaat tccttgtatt cgctacgagg aacagcaggg tctgcgttaa
    26221 attgtgacaa aacgatgttc cagatttcaa tataacggtc gttttcaata tcttctgcaa
    26281 gcaggcgaag accgatattt tctgggtcaa aggcttcccc acggtcaaag aagatttctg
    26341 tatctggtcc agaaggtccc gcaccgattt cccagaagtt gtcctcaatt ggaatcaagt
    26401 gacttggatc cactcccact tcaatccagc ggttgtaaga atctttatcg tctggatagt
    26461 aggtcatgta aagtttttca gcagggaaat caaaccattc agggcttgtc aaaagctcat
    26521 aagcccaagt gatagcttcg tcacggaagt aatccccgat agagaagttc cccagcattt
    26581 caaacatggt atggtgacgc gcggtcttcc ctacgttttc gatgtcgttg gtacggatag
    26641 ccttttgggc attggtaata cgtggatttt cagggataat ggtcccgtca aagtatttct
    26701 taagggttgc taccccagag ttgatccaca aaagagttgg gtcatttaca ggaaccaaac
    26761 ttactgatgg ttctactgag tgacctttgg tcgcccagaa atcaagccac atttggcgta
    26821 cttgtgcact agatagttgt ttcatattgt ctccttattc acttgtttaa tgtgattggc
    26881 tttccagcat ttccacatag tcaatcgcga cacagaggga aatgactagg tctgcataag
    26941 cgtcttcaag aaccgttacg gtataggtag aagtcagatg gaagagttcc ttcttaattt
    27001 ccgcaatcaa ctgatcgcga tcatccagca atttgaaatt caaatcccag atattgccct
    27061 cgatacgaag acctagatta tcaaactcat acttatctcg ccagaaggtc aacttcttac
    27121 gaatgacaaa actcgagcca tcccgaagct gaatttcaaa acgaggaagc aaggtcaaga
    27181 tttctttact aatctcactg acttgttcac cagccgcatc atagatggta aaggttttag
    27241 gaatcttaaa aaatgatccc tccacctgat aggcaatttc tcccctgtca tccttgatag
    27301 cgaagcgttc gcctccaaga cgaaactttt gtttgacaag aaatgttttc atcaacacct
    27361 ccaaaaatca aaagacaagc tcatatcacg aagggcgaaa aaccgcggta ccaccttcat
    27421 tcaatgaact tgtcattctc ttgttcttat gcaattgtat gattgagtag catgacttcc
    27481 tagcttagat ggctcgcagc accgccattt ctctggacta agacaagtga aaatcaattc
    27541 tcaactttct tattataacg tttttttaag cttgcgtcaa ctggaaatga tctccgttga
    27601 attagaccaa ttccctacat ctctgattac tttttcagga tatatttttt cttactgcca
    27661 tttttctttt tatcccaaat tttcatatta ctaaacacag ctactagaat atttccaaat
    27721 ataaaggtgc ctatcaccca atatatggac tcagttgtta ggtattgtcg atccaagcca
    27781 tcctttaaat ggaatagtat agcagtttgg ttaacaatca taaaggttgg ccagaaactt
    27841 tttttgaaaa aagtagacat tttcattatt tgttgccgct ttctgtaagg ttaatactca
    27901 ataaaaatca aaaagcaaac taggaagcta gcctcaagct gtacttgagt acggcaaggc
    27961 aacgctgacg tggtttgaag agtataggct tagtatacta ctaggcaagc aaataaacaa
    28021 ataaacaact agaatagaaa aagatagggc tctaaaaact gacttctatt ccttaaaaac
    28081 gaaccagctt gactgattcg tcttcttacg tttatctcct acttccgata cattttaaac
    28141 tgtaggaaga ggtcgctata tttccctgtc catttatggt caaatttctc ataaacttct
    28201 aggtgtttca tggtttcaac atcgggatag aaggccttat cttcctttgt ttcctctggg
    28261 agcaattcct tcgctggtag gtttggtgtt gaatagccga catactccgc attttggaga
    28321 gcattttcag gtttcaacat aaagttgata aaggcatagg ctgagttttg gtttttaact
    28381 gttttgggaa tgaccatatt gtcaaaccaa agattgctgg cctctgtcgg taccacataa
    28441 cgtagatttt catttttttc taacatttgg ctggcttcac cagagaaggt cacgccgatt
    28501 gcaacattat tctgaatcat atagcccttc atctcgtccg caacgatagc cttgatattt
    28561 ggagtcagtt tgtagagctt atccactgtc tcttccaact gctgcagatc cttggagttg
    28621 aggctgtagc cgagggaatt gagtcctagt cccagcacct cacgcgcccc atcaaagagc
    28681 atgatagaat tcttatactc cggcttccaa aggtcatccc aatgctcagg cgcttcatct
    28741 accatggttt cgttgtagac aattcctaag gttccccaga agtaagggat ggagaattta
    28801 ttacctgggt caaaggactg gttgagaaac tctggtccga tattttcgat tccttcaatt
    28861 tttgaataat caagcggaac caagaggtct tcgtccttca tcttgttaat catgtattca
    28921 cttggaatgg caatatcgta ggtcgttcca ccctgcttta tcttagtgta catggcttcg
    28981 ttggagtcaa aagtctcgta ctgaacttga attcctgttt cttctgtaaa ctgagtcaag
    29041 agttcaggat cgatatagtc tccccagtta tagataacca atttttgact atctcgacta
    29101 ttgattttac tatctaaatg agtcgcaatt ccccacaaga caaggataat cgctgcaatt
    29161 cctgctaaaa atgaatagat ttttttcatg cttgctcctc cttctcacga gagataaagt
    29221 aataacctac aactaggata atactaaaga gaaagactag agcagacagg gcattgattt
    29281 ctaaggaaat ccccttgcga gcacgagagt aaatctcgac tgatagggtt gaaaagccat
    29341 ttcctgttac aaagaaggtc acggcaaagt catctaacga ataggtgaag gccatgaaat
    29401 aaccagtaat gatagacgga gtcaggtaag gaagcatgat ttccttgaac atctgaaatt
    29461 gactagctcc caagtcatag gccgcatgaa tcatgtcgcc attcatttcc ttgagtcgag
    29521 gcaagaccat caagaccacg ataggaatgg agaaggccac gtgactagat agaacggtca
    29581 aaaagccaag tgaaaacttg agttgggtaa agagaatcaa gaagctagca ccaatcataa
    29641 cgtcaggcgc aaccatgagg atattattga gtgatagaaa ggcttcttgg tatttcttac
    29701 gagactggta gatgtaaatg gcaccaaaag tcccgataat ggtcgctatc aaggctgata
    29761 ggaaggccaa gaaaaatgtc tgagccaaaa tcagcatgag tctcccatct ccaaacatgg
    29821 tttcaaagtg agtccagcta aaacctgtaa agctattcat atcatcacca gcattaaagg
    29881 catagccaat caagtaaaag ataggcaggt agaggaccag aaagaccagt cccagataaa
    29941 ggttggcaaa ttttttcatc gttctctcct ttccttagtc acccacatgg tgatgaacat
    30001 ggtcaggatg agaatcacac cgatggttga acccatacca tagttgtcat tggttagaaa
    30061 attctgctca atagccgtcc ccaaggtgat aacgcggttc ccaccaatca aacgggtcag
    30121 catgaagaga ctcaaacttg ggataaagac cgactgaacc ccacttcgca caccgttcat
    30181 agatagaggg aagatgacat gacggaaggt ctcccactta gttgcaccaa ggtcataact
    30241 agcattgatg agattattat ccatatcgtc taagacattg aaaatcggca aaatcataaa
    30301 ggggagctcg atgtagcttg cgacaaagat aaaggaaaaa tcggtaaaaa gcaactgttg
    30361 tgaaccaatt ccgataaatt ccaagaattg gttaatagag ccattttgac caaaaatccc
    30421 gataaaagca taggctttaa ggagcaaatt gatccaggta ggaaggataa tcagcatgag
    30481 ccagagttga cggtgtttga gacgggtcaa aaagagggcc gtcggataac tgataagcag
    30541 tgccacaaag gtcacaatgc ctgcataaag cactgagttg aaactcattt taagataggt
    30601 caagttttgt gacgcaaagt aagatttgta attttctaaa ctgaactggc cttcgatgtt
    30661 gaaaaaggat tgaccgaaaa tcaagaccaa gggtgccaat acaaagagcg caatccaaag
    30721 catgtagggt actacaaaga gtttagagct tgttttcttc atctctttcc tcctcgattg
    30781 cattgatcaa acctgcttct tgctcttcga tttctacgta ctcctcaata cgagcatcga
    30841 actcttcttc ggtttcattg agacgcatga tgtggatgtc ttctggttca aagtccagac
    30901 cgatttcctc acccacgata gccttacggg ttgagtggat catccattca tttccaagtt
    30961 cgtcataggc gataatttca taatgaactc cacggaaaag ctgggtatcg accttaactt
    31021 ggagcttgcc ttcttcagga agggtaatgc gcaagtcctc tggacgaata acgacctcaa
    31081 caggttcatt tggcttcatc ccaccatcaa ccgcttcaaa gcgtttgccg ttaaattcga
    31141 ccaagtagtc ctcaatcatg gtacctggca agatgtttga ctccccgata aaggtggcaa
    31201 caaagtggtt gattggctca tcgtagatgt ccacaggggt tccagactgg acaatctcgc
    31261 catcattcat aacgaaaatc cagtcactca tggcaagagc ttcttcctga tcgtgagtga
    31321 caaagacaaa ggtaatgccc aatcgttgtt gtaattcacg caattcgtac tgcatgtctg
    31381 ttctcaattt caagtccagc gctgataaag gctcgtccaa caagaccaca cggggttggt
    31441 tgatgatagc acgggcgatg gccacacgct gacgttgtcc tccagaaagt ttgcggatgg
    31501 aacgtttttc ataaccttcc aactgaacca tcttgagaac ttccgctaca cgctgctcga
    31561 tttctttctt atcaatttta cgcaagcgaa gtggaaaggc aacattttca aacacattca
    31621 tatgtgggaa caaggcatag gattggaaga cggtatgtac gtcgcgcttg ttggttggaa
    31681 tatcattgat acgaacaccg tctagcatga tatctcctgt cgtcgcatcc agtaaacctg
    31741 caataatgtt taggatagtt gatttccccg aaccagatgc acctagaagg gtgtagaatt
    31801 tcccttcttc caactcaaag ttgatgtctt tgagaacctt ggtgttgctg tcttcaaaaa
    31861 ctttagagac gtttttgaat tcgataattg gctttttcaa ttggcataaa ttccttcttt
    31921 ttcatagatt aaccgatcgg ggctctgtca ggtccccact acctcttgca gggagtaaaa
    31981 ccacctgcat acatcttcgc taccgatagg ctttcaccca agatccggac ttctctttca
    32041 agcgtaatac ctgagtgttc cttgactttt tcgataaccg attggatcaa gtcctcgtag
    32101 tctttggccg ttccatctgc gacattgatc ataaatcctg catgcttttc tgacacttct
    32161 acgccaccga tacgatagcc tttcaagcca gcttctgaaa ttaactgacc tgcaaaatgc
    32221 ccgactggac gcttaaagac cgagccacaa gatgggtatt ccaaaggttg cttgagttca
    32281 cgtaggtgcg tcaagcggtc catttcctgc ttgataacct gatgggttcc tggagctagg
    32341 gcaaatttaa ctgacaagac aactgcacca gactcctgaa tagctgaatg acggtaacca
    32401 aaagccaagt ctttagcaga cagggtttcg atttctccat ccttggtcaa gaccttacaa
    32461 gactgcaaga tgtgagcaat ctcgccacca taggcacccg cattcataaa gacagcaccg
    32521 ccaacgcttc ctggaatacc acaagcaaac tcaaagccag ttaaactatg acggagggca
    32581 atgcgagttg tttcaatcaa gttagcccca gcttctgctt caatggtata gccatcaaca
    32641 gaaacgttat tgagcttgtc acacaagatg acaaatccac gaatcccacc atcacgaacg
    32701 atgatattgc ttgcattgcc aagaaccatc caagggatat tttcttggtt ggcaaatttc
    32761 acaacgcgag ccaactcaaa acgatttcgt ggaaagacca aataatcagc ctctccacct
    32821 acttttgtat aactatagct atgcaagggt tccttaaaac ggatatcaat tccttctaag
    32881 atttcaagca ttttttctct tacagacatg tcactcttcc ttttacaaaa ttcattccat
    32941 tataccattt ttagagacat ttgacgacca taaaaatacc ttgtttggat tttgcataag
    33001 aaaaagaggt tccccccttt ttatgatttt ttacaaaaga tttccttggt tccataggcg
    33061 accagaacga gctccagtgc tagaatcact tcaaccaaga ctggatttgt caaccagcct
    33121 acttggaaaa gagatggtgc cagatcaaag aaggcatgca agccataggc tgctaggaga
    33181 taaatccatt tcttctggcg aacagcttgg taaacccaaa ctgtcaaaag taattggaaa
    33241 ccaagcgcca agattcgctc aaaaccaagc aaataaatct gccagaccga aagtgactga
    33301 atggttttta acatattttc agacagtaat tgcataacct gtggattctg agtttgaact
    33361 gccgaaagaa caatgtaaag attgagtaaa ctagtaaggc ctagaaaaat caactccaag
    33421 ccaccatgcc ccagtccata ggccaaggcg tctgcctttt ccaaacttct ctttttctcc
    33481 aaccatttga agaaaacaag acgagccgtt tcctcaaaaa atgctgccat ggctaggcca
    33541 tagataatat agataagcgg atgatcttgc aagagggcaa tactaccgtc tttttgaggg
    33601 tgcaaaatca agatatgcac cagtttttcc aaaatctgcg aagagacaaa gaaagcgact
    33661 gcacccaagc ccaagacagc tagattaatc tggtatttct ttttggcaaa ccaaatgctt
    33721 cctatcagaa aagctagcaa cagcaacatg gtaataatga tatgaatggt cattttcttc
    33781 tcctattctg ccttttcaat atcttttttc atctcgtcaa cattgaactt agcaaacaag
    33841 tattgacggt cttggactgg gaaacgttgg tccaactggt caactgctcc cacctcgata
    33901 atgccttcct tgatgacaaa atccatgaca tgtccaccga aggtcaaatc atctgatatg
    33961 aagtgcagat ggtagcctgc cacactgacc ccatggaaaa tctcaggcgt ccagaaacca
    34021 acaatagtcc ccgcaacatt gtcacgacta tattccggtt gatgggttgc gacatcagca
    34081 aacttggtat cgggtgttga cttaggaatc atacgcacat gcatatgtaa aaattccccc
    34141 cgaatcttga tagagcggaa aagattttcc ccatcataat aagactcaat tcgttctttc
    34201 aattccttgt ctgtcatctc aaagcgctgg cggaaaatga cctctgcccg atgcggtacc
    34261 actgcagcgt aaggaataag ggcatctggt gacacttcca caatttctgg ctggtctcct
    34321 gaccctttgg cctgataagc cttgccatcc aagacaatca attccccatc aatggaatcc
    34381 aaggttccca aaccaaggtc accatgttct agcaattctc ctactgtcat agtaccacca
    34441 taaaggccag ccatcaaggc tccaagagta ttgtattgaa ataatttcac tggttcctgc
    34501 acgttcttat ccattcactt tcttgtctgt tattctataa atcttactcc taagtatacc
    34561 acatttgccc ctagatgtga acgagagaaa cgctctagac attgccaaga aggaaaaaaa
    34621 agggtacaat gtaacaaaat caagggaggt ctggaatgaa gaaacaaagc aagtacaaag
    34681 aggtcgtttc ctatctgaaa aatggtatcg agtctggacg atttccgacg ggtagtcgcc
    34741 tgccttctat ccgtcaactg agccttgact ttcactgcag caaggacacc attcaacgag
    34801 ccctgctgga attacggcac gaacaatacc tctatgccaa gcctcagagt ggctactatg
    34861 tattagaaca agggcaacat caagacctag aaatcgaggt taccgacgaa catgccagtg
    34921 cctatgacga tttccgactc tgtgtcaatg aaaccttgat tggccgagaa aactacctct
    34981 tcaactacta tgacaatcaa gaaggattag aagacctaag acagtccatt cacaaactcc
    35041 tctttgagca agctctctac tgcaaggcta accaactagt actgacttct ggaacccaac
    35101 aagccttgtt tatcctctct caaatatcct ttcctagaca agccaaggaa atcttggtgg
    35161 aacagccaac ctaccatcgg atgaatcgcc tcttgattgc acaggggctg gactatcaaa
    35221 cgattgaacg aggcattgat gggattgact tggaggagct ggaaggccac ttcaaaacag
    35281 gaaaaattaa gtttttctac accattcccc gatttcacta tcccctggga cattcctatt
    35341 ctgagcaaga caaacgatct attcttaact tagctgccaa gtatgatgtc tatatcgtag
    35401 aggacgatta tctgggtgat ttggactcca agaagggcca aaccttccac tatcttgata
    35461 cagaggagcg tgtcatttat atcaagtcct tctcgaccag cctttttcct gcccttcgta
    35521 ttacagcact cattcttcca aatgctatca aagaagcatt tgtggcctac aaaaatatcc
    35581 tagactacga cagcaacctc attatgcaaa aggccctgtc actctatatt gacagtcaat
    35641 tgtttgaaaa aaatcgtttg gctcgcttga ccaatcatga atcttaccaa aaacaaatcg
    35701 aggaaaggat aactaaaaca ccttgtcccc ttcctcatta ttccctacac gatggtttat
    35761 tgctagacct gagacagtat cctaaaatcg ccagtctcaa acacagtcaa ctgggcttgg
    35821 acttctttga agaggcctat ttaagcacct gtccttatca atttgccaag gtgtccctag
    35881 acaatctgga aaatgtttta aactatttaa aagcagaatt ggaatgacat ccaactctgc
    35941 tttttcttat tcttcaactt cagttagact tgctgctttt tcaagatagc tttggtaagt
    36001 tccttcatcc ttaagttttt ggacgacctt gtctaccact tctttcaaat catcactatt
    36061 ttttctaaga gcaacggcat tggcgtcgcc gtccttcatc ttcaagctga cagttgcgac
    36121 agctaagcca gcgtttttag cagcataact aagtgcaaca ggctcatcca tatgaacagc
    36181 atctattttt ccagcctgca attcattgac tgcttcaccc atattagtta gggaagttaa
    36241 ttgaactttt ggcaattgtt ccttgaccat tgattctgga acagtccctt tttgggctgc
    36301 aatattagca ctttctaggc tagttaaatc cttgtatttt tccacatcag ccttacgaac
    36361 caagaaacta atcttgtttt catagtatgg gattgaaaaa tcaaagactt cttttctctc
    36421 gtcagtagca ctaattcctg caactgctag gtcagcctta ccagtttgaa gactggtcaa
    36481 aacattgtca aaactcatgc ttgagatttc caacttaacc ccaagttcat cagcgatagc
    36541 ctgagccatg tcgatgtctg caccgactac ctggttcttt ccatcaacca atgattgaaa
    36601 ttcaaagggt gcatagtcag gactggttgc cacaactaat ttcccttttt gtttgatagc
    36661 atccacagca gactgagaac cattagaacc tgactgacaa gctactaaga agaaacttgc
    36721 aagaaaatta cataaaacaa atatccattt ttttgatttc ataaataaac aacctctctg
    36781 ttaattttgt ataattataa cgatatccaa gttacttgtc aagtgttttt taaattttta
    36841 tctcaaaaat attttttcgt tcaaaaaaag gagccatcag ttgatttcaa gctccctttt
    36901 atacagaatt aaactatttt atagttcgac aatcttacct gtttcaaagt agacaaccca
    36961 ttcacagata tttttagcat agtcaccgat acgctccaag taggaaataa cttggaaata
    37021 atcacgaccc gtaacaatgg cttctggatt tttcttaatc tcttcagtcg caaggtcacg
    37081 gatagtttca aaatagtggt taatttgctc atccatggag gccacccggt atgcgtcgtc
    37141 aacagaacca ttaagataaa gatcaagtgc tgcttccaca acgcttttaa cttcacgtcc
    37201 cattttttta atttcttcct ctacagctgg aatgcgctct tcccccttca tacggatggt
    37261 tgcctgggca atggctacag cgtgatcccc catacgctcc acatctgata cagccttaag
    37321 gacagtcaag actgtacgca aatcttgaga gactggttgt tggagtgcga tcatttcaaa
    37381 tgatttcttt tccagtttca cttcgtattc atttacttct gcatcatctt cgatgacctc
    37441 ttttgccagg tcacggtcat gcgtgacaaa agcacgtacc gtacgattga tttgtgagag
    37501 cacttcttgt cccatagcgt agaactggtt atgtaatttc tctaaatctt cttcaaattg
    37561 agatcgtaac atctttcatc tccttatcca aattttcctg taatatagtc ttccgtttcc
    37621 ttgtgttggg gatcaaggaa catctgcttg gtatcattaa attcaatcaa atctccatct
    37681 aggaaaaatc ctgtcttatc agagatacgt gaagcttgct gcatggaacg ggttaccaga
    37741 agcatggtgt acttgtcttt tagaccatac aaggtttcct caattttacc agctgaaatc
    37801 ggatccaaag ccgaagttgg ctcatccaag aggatgattt taggactagt tgccaagaca
    37861 cgggccacgc agacacgctg ctgttgacca cctgacaatc caatagctga atcatataga
    37921 cgatccttga cctcatccca gatagaggca ccttgcaagg ctttttctac ggcttcatcc
    37981 agaacctgct tatccttaat tccattgata cgaagcccgt agacaacatt ctcatagata
    38041 gtcataggga aaggattagg ttgttggaaa accattccga tttccttacg taattcaacc
    38101 gtatctgtac gcggactgta gatgttgtga ccattgtaca ccacggatcc agttgtggtc
    38161 acctctggat tgagatctcc catgcggttg agagacttga ggagggttga cttccctgat
    38221 ccagatggac caatcaaggc tgtaatttcc ttaggttgga aagataggga aacactattc
    38281 aaagccttct ttttattata ataaacggac aggtctgata cctgtaaaat cgcatctgtc
    38341 atacggtttc ctttctaacc aaagtgacca gatacatagt cattggtgga ctgtagcttg
    38401 gcattttgga aaatagttgc agtcttgtca tactcaatca aatcacccaa gtaaaagaag
    38461 cctgtatagt cacttgcacg agcagcctgc tgcatattat gcgttacaat gatgatggta
    38521 aagtttttct tgagctcaaa catggtctct tctagttgca tggtcgcaat cggatccaag
    38581 gctgaggctg gctcatccat taagaggata tctggcttaa cagagatggc acgagcgata
    38641 cagagacgtt gttgctgacc acctgataag gtcaaggctg acttgtggag atcgtcttta
    38701 acctgatccc agagggcagc ctgacgaagg gaggtttcta cgatttcatc taggacttgc
    38761 ttatccttaa ctccagcacg ttcatgcgca aaggtaatat tacggtaaat tgacttagca
    38821 aatggattgg gacgttgaaa aaccattcca atgtgtttac gcatttcata aacgttgatt
    38881 tctggacggt tgacatcaat tccacgatag agaatctgcc cagttacttt agcaatatca
    38941 atagtatcat tcatgcgatt gagactgcgt aagtaggtag atttccccga tcccgacggg
    39001 ccaatcaaag ctgtaatttt atttctttca aattgcatat caatcccctt aatggattca
    39061 tttttaccat agtaaacatg gacatcctta gtagaaaggg ctactttttc ttcaggaaag
    39121 gtaaggatat gcttctcatc ccagttatat gttgacatgg cttctccttt aggcagcggt
    39181 taatttcttg tgtagatagc ttccgaactt acgagctcca aagttaaaaa tcaggataaa
    39241 gatcaggagc acagcggcag aacctgctga tacaatggtt ccatctggaa tagtgccttc
    39301 actattgact ttccagatat ggacagccaa ggtttctgct tgacggaaga tagagatggg
    39361 gctagtcaca ctgaggatat tccagttaga ccagtcaaga gctggcgccg attgccctgc
    39421 tgtatagatc agagctgcag cttcgccaaa gatacgacca gatgccaaga cgacacccgt
    39481 tacaatacct ggaagcgctt ccggaataac aacatgaacc actgtctccc agcgagaaat
    39541 cccaagagcc agaccagcct cacgttgggt atggtgaacg tgtttcaaac tatcctctac
    39601 attacgcgtc atctgaggca agttaaagac tgtcaaggcc aaggcacctg aaatgattga
    39661 aaatccatac tcaaactgga ctacaaagat caagtaacca aagagaccca ccaccactga
    39721 tggtaaagag gacaaaattt caatacaagt ccgcacaaag ttggtaacag gacctttttt
    39781 agcatattca gccaagtaaa tcccagctcc catagaaaga ggtacagaaa taatcaaggt
    39841 aatgaccaat aggaaaaagg aattgtaaag ctgaatgcca atcccaccac ctgcttgaaa
    39901 agcagaagac cttccagtca agaaagacca agagatatgg ggcaagcccc gaaccaagat
    39961 atagagaatc aaggaagcca agattgtcac aatgatgcta gcaatcgtat agaggacagc
    40021 tgttgcaagt ttatctaatt tcttagcgcg cataattttt ctttcctctt tctttcgtaa
    40081 tcaatttaat cacactgtta aaaactaagc tcatcaagag cagtaccaag gccagtgacc
    40141 agagaacatt attatttaca gttcccatga cagtgttccc aattcccata gttaatatag
    40201 aagttaaagt tgcagctggt gtggtcaagg aagttgggat aacagctgag tttccgacaa
    40261 ccatctggat agctagagcc tcaccaaagg cacgcgccat cccaaagacc actgcagtga
    40321 aaataccaga acgggccgcc ttcaagatca cacgccagat agtctgccag cgagtggctc
    40381 ccatagcgaa actggcttca cgataataac gaggaaccgc acgcaagcta tccgttgtca
    40441 taaaggttac ggtcggcaaa atcatgacaa agaggacgga aatccctgac aaaatcccaa
    40501 aaccagtccc accaaagaca ctgcgaacaa agggaacgac gacttgcaag ccaataaatc
    40561 cgtacactac tgaaggaatc ccaaccagga gttcaatagc tggttgcaaa atcttcgccc
    40621 cttttggtga tacttcggtc ataaaaactg ctgcaccaat agcaaagggt gttgcgataa
    40681 gggctgagag aatggtaacg ataaaggaac ccaaaatcat aggaagggca ccaaattctt
    40741 tactagaagg attccaagtt cctcccaaaa gaaagtcaaa gatattcaca ccattgacaa
    40801 agaaggtcga caagcctttt tgcgctacga aaaccaaaat catggccaca aggatgacta
    40861 tcaaagaaag acaggcaaag gtcaaacctt ttcctaattt ctccagacga gaattctttg
    40921 atggaagcaa cattttctta gctaattctt cttgattcat tattgtctcc cttccaacac
    40981 tgtcacagtt ccggcagcat ctttttcaac cttcatttcc ttaatcggaa tatacttcaa
    41041 tcctttgaca atcccttctt gggtctcatc cgagagaaca aaattgagaa attctgcagc
    41101 caactcattg ggctgcccca atgtatacat atgctcataa gaccacaagg gccaattatt
    41161 gctacttata ttttctggac ttaagtcata gccattcaac ttcatgcttt tgaccgaatc
    41221 atctatatag gtaagagata aataagagat agctcctgga ctttttgata cgattgattt
    41281 taccgctcca tttgaatcct gctcctgact ttgcatggca gactgacctt ccataatgac
    41341 agtatcaaag gtagcacgag agccagagcc ggctgcccga ttgataacag agatgggtaa
    41401 gtccttacca ccaacctctt tccaattggt tacctcacct atgaagattt gacgaagttg
    41461 ctctgtcgtt aggttatcaa catcaacctc cttattgaca atcagagcca agccagctac
    41521 cgcgaccttg tggtcaacaa gagcagaagc atcaattccg tctttttcct cagcaaatac
    41581 atctgagttt cctatatcaa ctgccccaga ctgaacctgg gacaagcctg taccagaacc
    41641 tcccccttgg acattgaccg tttttccaac atggatcgtg ccaaattcat ctgccgctac
    41701 ttcaaccaag ggttgcaagg cagttgagcc aacagccgtt atggattctc cacgatcaat
    41761 ccagctagca cagcctacta aacaagccgt cagccaaaaa gcgataagag acagagcaag
    41821 cttttttctt tttttcactg tttttctcct cgaaaataat tatgaatact gtgaattttt
    41881 taagtagttc tttatgagtt gacgcatgaa ttcttaccaa atttctgcgc aattgattat
    41941 ttatataata taggctatat tactctttcc taacctcctt ttttcatatg tggataaaat
    42001 ctcttgtcta tcccttcccc cattgtcacc cattatagtc atttcgtgtc tctttttccc
    42061 ctttttaatg caagggaaat tactctcctt agatgataat ccaaaagcta gaaaggtatc
    42121 tcaaacctct ctactctccc agactagttt acaactaaaa ggaaaagatt ctattttatg
    42181 agaaatctag tttacaagcg gtaagaacgc taataactaa acttcttgta ctctttgaaa
    42241 atctcttcaa accagtgttt tgagctatct atggctagct tcctagtttg ctctttgatt
    42301 ttcattgagt agtaaaacta catgtaatgg caatcaagat atcaagaatc atcctactaa
    42361 aaaaatccat actttcacta taacatagaa taagatattt gactagcatt ttcatttgaa
    42421 tctgaggcct tttggaaaat aatttttcaa aacatttcca gtaacctttg caaagcccaa
    42481 gccattgcct ttaaccaaaa cttggtacca accatttggc agactttctg ccagctgaac
    42541 ggtttctcca gccgcatact tgacaaacgc ttcttggcca atttcaaccg actgttcgac
    42601 ctgactcggt ttcaaggcta aaccaagagc gaaactgggc tcaaagcgtt tcttcttaaa
    42661 agtacccaga tgcagtccat tgcgagcaat cttgagcttc cataaatctg gcaaaagttc
    42721 tggcaagaga taaagctggt ctccaaaaat ctgcaagata cccggtagat tgaccttcaa
    42781 atggttttgg gcaaattcct gccacaaggc aacttgttca cggctgaggt tactcttact
    42841 tgccttaaat ttaggagctg gattgttacc cttaaactgt agatgggcaa caaactgacc
    42901 ctctccctta aactgatgag gatacatccg agccgtttct ggcaggtcaa taccagctac
    42961 cattccattg atatgctcta ctggcaacaa gtcaaaatca tactcttcca gcaaccaatt
    43021 gacaatctct tcgttttcct cgggtgccca ggtacaggtc gaataaacca gatgaccacc
    43081 ttcagctaac atggtcactg catcctccag aatttctctt tgcaagctag cacattgact
    43141 cggataatct aagctccaat agtccatagc atcaggttgc ttacgaaaca ttccttcacc
    43201 agagcaaggg gcatcaagaa cgattaagtc aaaatagcct ttaaagacct tgaccaagcg
    43261 gtcggcagat tcattggtca ccacgacatt tgtcgctcca aaacgctcca tgttttcaac
    43321 caaaatctta gcccgtttgc ttgaaatttc attggaaaca agtagcccct cccctgctag
    43381 ataggctgcc agttgagttg atttgccccc cggtgcagca gccaagtcca agaccttcat
    43441 accaggactg ggttgggcta cttgagccac catttgagca gcaggttctt gcgaataaac
    43501 taaacctgta gcatgctcag gcgatttccc tgaaaccttc ccatagtggc cccaaggggt
    43561 ttgagtaatg gcatcagaaa aggaaagttg ctcttctttt aagggattga cccgaaaggc
    43621 cgaaaccgct tcctcctcaa aagaggcaag aaaatctctt gcctcatctc ctagtatctc
    43681 tttatatttt tcaacaaatc cttctggaaa ttgcatttaa gttcttttcc tttcgtaaat
    43741 ataggactga atttcctcct gcatctcaag aggcaccatc atgaccggct gtctggtttg
    43801 aaaatcagga gcttcaccaa aaagggtcac aacccgatag cccagacttt cccctaaaat
    43861 actagctgcg gcataatccc atggttgcag ataagtgaga taggtcaaca aacgccctga
    43921 caaaatcttg gcaaaactaa tggccgcact tccatagaca cgaacaccaa gaaccgctcg
    43981 gctcaaatca gccagccccc attcattggt ttccagcata ccactattcc ctgcaatgag
    44041 aaaatctcca agtggtttag ttttaaaagg agctagggac ctatcattta gacaaactgg
    44101 aaattcccca ccaccgtggt aacaatcccc tttgaccaca tcataaatca gaccaaactg
    44161 tccctgacca ttttcaaaat aagccatcat aacagcaaaa tcttcctgct gggctacaaa
    44221 attattggta ccatcaatgg gatcaatgac ccaaaccttg ccctcttgaa ccgaggctcg
    44281 cagacaacct tcttcagcac aaatcttatc ctcaggataa cgggacaaaa tctcaccaac
    44341 caagagttcc tgaacttctt tgtccagtct ggtcaccaaa tctgttggag aggacttggt
    44401 ttcaacacgc aagtcttcct gcatatggtc aagaatgtac tgacctgctt tcttaacaag
    44461 ctctttagca aattcaaatt tactttccaa gagaaatctt tccttcccct ttttctttgg
    44521 cagcctgaac tgctcggtaa agtgaatagc cactaaccgt ttcaaattct cgtcccaaac
    44581 gtttctcttc gctcttgctt ggcacgaccg ctttgaatcc cttataggag tccagtaact
    44641 ttttagcctc tactttgcct tcataggcag cttcaacatc attaaaaaaa gaaagcactg
    44701 aagcaagttc ttcagtgctc cacgacaaat ctagtgggta actatactgt ttgttcatta
    44761 actaatacca gctctcattc ttgcttcttt tagttcttgc ttacgataac tacgagggag
    44821 aaaagcacga atctcatctt cattaaaacc gatttgcata cgcttggcat caataataat
    44881 tggacgacgc aaaagactag gatactgctc aatcaaatga agcaattccg ataccgaaat
    44941 actctctaca tcaatattca atttttgaaa aatttttgaa cgagttgaaa tgatgtcatc
    45001 agtaccattt tcggtcaagg aaaggatgtg ttgcaattct tttcttgtta aaggactggt
    45061 cataatattg tgttccacaa agggaacctt atgtttttct aaccaggcct tagccttacg
    45121 acatgatgta cagctcggtg atagaaatag tgtaatcatg cttttctctt cttatctata
    45181 ctttgctact tctattatac aaaaaaataa agcgcttgac tagggatttt tagaaaaaaa
    45241 gcctattttt tcaagaaaaa taggcttttt gcgaacgatt gacacaattg gatttggtta
    45301 attcactctt aacgatggtt ttaaacgata tatattttta tatatgtaaa ttaaaaacat
    45361 ctttcctttc acttcctacg acttttcaga tacagatagc caaagaagtt ttcatagagg
    45421 gcaaaaaaga ggaggaaggc atgaagaaag aaggtctctg gcaaaatcat aataacagga
    45481 tccttggctg gatcaaaaag ccaggtatca tctcccacaa agagaatttg atggaaaaga
    45541 gtaaagaatt ggtcaaaacc aatcaaaact cccccaagtc caatcatcac aggtaagact
    45601 actagagcca ggagactttt tcgataaaga gacaaaaagt cctttttcac aatcctattg
    45661 acaaagacat agaaacttgg cagtgtcact agagctacta gctgaaccaa atgaaagaga
    45721 ttcttgacca ctgcgaaatg gtgcagacca gctgctgacg aacgaaaatc aggcatctgt
    45781 aagacctgac taaaaggatt ggtcagataa ttcatcaaga tatgaaaatt gtattgaatg
    45841 gtttctggtt ttagatagac tcgattcgtt aagtttagcc actgaatctc cataggatag
    45901 aaaatccaag ccagataaat ggtcagaagg atggagaggg agaggagaaa gagcatagag
    45961 ccccaaaaga tcaatttagt tttcatcaaa atcccactcc gcaaggctag aaaccacatg
    46021 tgtcggtgcg attggcaggc cagctacttc ttctgcctta gtaaaacctg tcgtcaccaa
    46081 gagcgttgga atgccattgt caatcccagc ccgaatatca gtcaaataat tgtccccaac
    46141 catgattaac tcttcacgtt ccaaacctaa gtgctcaacc gccttgtcca taatgatggc
    46201 atttggtttt ccgatataaa ccggcttcac tcgtgtcgct acttcaagca gcgtaatcag
    46261 tgagccagca cctggcaaaa gaccgcgttc cgtcgggatg ttgaggtcag gattggttcc
    46321 gataaaatgg gcaccctttt gaatagcaag agttgctgtg gcaaattttt catagtcgac
    46381 ttgccaatcc agaccaacta ccacgtaggc aggtttttcc ttgtcttcca cataaccagc
    46441 cgccttgatg gcttccttga gtcctgcttc tccgacgaca tagacggtct tttcaagccc
    46501 caaatcattc atatagtcga tggttgccaa agtcgctgtg tagacagtcg ataggggcgt
    46561 atcgatatta aaattctgag ccaacatctc cttaacactc tctggagtgc gggttgtatt
    46621 gttggttaca aagagatagg gaatgtcccg cttttgcaat tcatgaacaa aagtctctcc
    46681 agcagggatt cggtctttcc ccttataaat ggttccgtct aaatcaatta aatagccttt
    46741 atatttcatc tatttctccc taagcctttt ttatttcttg ccaagtaatg attgcttggg
    46801 cattgataac cccatcactt gtaatttcat gcttgctttc cagtccagtc cgttcaacag
    46861 ccgatgtaat caccccacct ggtcgaactt ccttgacata cttgaggttg attttcttgg
    46921 gaatatagtg ggtcaaaaaa tccgctccca tgacctcaaa aatccagtcc aagtatttac
    46981 tgttattgac atgaccattc atatccaagt cgtaaaaacg aacatggtaa tccttgctga
    47041 tcggttcttc caaggactca tacttcggtc cacggataag ttttttatca aaatcagact
    47101 ggtaaggagc cacaatctca ggttcaacaa catggacttt tcgactgtcg cggtccatga
    47161 gaacaaaggt cgccatcatg tggatgagct cctgctccgc ttcattataa atagtaaagc
    47221 gacggtagca aaaaagtcga ttgtagctca aggcttccgt ttcgatggta atttcttccg
    47281 caaaacgagg caaacgaacc acctcaatat catattctac gataatccag accagattat
    47341 attcttccaa aatggcctta tcactaactc ccagttcaat cgactgcatc cctgaaactt
    47401 gcagtgacag caaaatcaca tctggaagtt tgatatgacc gttcatatca gccatatcaa
    47461 aaggaatttt cattttcatt tgataagtta agcccatgat cctactccaa aataaatcgt
    47521 tctgctacag tatctcccaa aaagagacct ctctttgtca tgcgaacgtg gtcaccctca
    47581 atctgcatga ggccttgttg aaccaaatct ctgacaattt ctccataaag tccagcaaaa
    47641 gactgtccaa atttttcctc aaatcgcgcc atggaaaccc cggatttctt gcggagtccc
    47701 aagaacattt cttcttccat ttgctccttt tgactcaggt gatcttctgt aatacaagca
    47761 ttgccttcct caaccgcact gagataatga cgaatgggac catgattttt atagcgtact
    47821 ccattgacat aaccagatgc ccctgcacca ataccatagt attcagcatt gtcccagtac
    47881 atgagattat gacgactttc aaaaccgggt ttggagaaat tagaaatctc ataatgctca
    47941 aaacccgctc gctccagctc tgcaatgatg tactcaaaca tctccgcttc tagttcctcc
    48001 ttaggcagag gcaatttccc acgtcgcatc cggttcataa agaccgtatg gttttctaaa
    48061 atcaaactat acaaactcat gtggggaata tccaatccaa tggctttagc cacattttcc
    48121 tttacttgct ccatggtctg accaggcaga gcataaatca aatcaatgga gatattgtca
    48181 aaaccagcca gtttcaggcg atcgatattt tcataaatat ccttctccaa atgactgcgc
    48241 ccaatctttt tcaacatctt atcatcaaag gtctggacac ctagcgaaac acgattgaca
    48301 gccgaatttt tcaaaacagc tatcttatcc gcatccaaat cgcctggatt ggcttcaatg
    48361 gtcaactctt ccaagacaga caaatccaag tttttagtca agccattcag taacacctcc
    48421 agttgcggag ccgacagggc tgtcggtgtt ccaccaccga tataaagggt tgacaacttt
    48481 tcaatatcat aagaacgaaa ctcttccagc agatgctcta aatagctgtc gactggctga
    48541 tttttgatga agacctttga aaaatcacaa taataacaaa tctgggtaca aaatgggatg
    48601 tgcacatagg ctgacgttgg ttttttctgc atagtaatta ttataccaca aagactagat
    48661 tccagataaa aatcaccatc cccagataca tagtccgtcc ggagatggtg atggtttatt
    48721 cttctgttat atcaatcaca atctcttctg agtcatcaag agcttcggct ttttcttgcc
    48781 attgctcctt gagattattt aattgatttt ttgatgcttc tgtcgcttga aaagcatagg
    48841 atttagtttg agcaagtata ctgtccacag tgatttcacc tgactcaacc tgttcttttg
    48901 ttttcagaac aaaatctgta gcctgctcct taacttctgt cagtttttca cagacttgct
    48961 ccttggcata ctccggatct tctctcaaat catctagaaa atcttgagcc tgactgcaaa
    49021 cttgtttgcc cttatcactt gttaaaaaca aggcaagagc tgcacctgaa acggttccta
    49081 aaaggattga ggataattta cccataagga ttctcctttt ttattttttg aaaaatttac
    49141 ttgcaagacg aagagctgac agacttgcac cagtcttgag tgtttttgaa ccagctgatg
    49201 aagctttctt gctcaagaca cgcgcatggt cattgaggtc tgaaacagat agagataaat
    49261 ctgcaacagc actgaagagt ggatcaatcg tagccacctt gacattgata tcatctgcca
    49321 agacattgac cttagccaac aactcattgg tgtgatgcaa ggtcacatcc acatctgaag
    49381 tcaaggtttt aatcgtcttt tctgtttcat cgatgacacg accaagcttt tgtacagtaa
    49441 tgatcagata gaccaaaaag acaatcaaag ctagggcaac aagaatatat gcaacttcta
    49501 acatttagtt ttcctcctct gtaatatagt aaggggcctt ctttcgattt tgataaataa
    49561 cgatcattat accgagaccg ataaggacaa ctgacagcca ttgggacact cgaaagccga
    49621 agaacatgag actatctgtt cgcatacctt cgataaccat acgaccgaaa ccataccaaa
    49681 tcaagtaaaa ggccgtgata tgacctcgtc tgagactctt ccatttccgt ctaaaaatca
    49741 gaatcaaggc aaagccaagc agattccata gagactcata aaggaaagtc ggttgacggt
    49801 agctcccctc aatatacatc tggtcacgga taaagccagg tagataatcc agattatcca
    49861 ctgttgcacc ataagcttct tggttaaaga aattacccca acgccccaaa ctttgagcaa
    49921 tcataacgct aggcgccgca atatctagaa aatcccaagt attgatgagt ttacggtcag
    49981 caaagatata gagcacaaga gccccagtta tcaaaccacc gtaaatggcc aaaccaccat
    50041 tccaaatggc aaaaatctct cctaaattct gactatagta atcaaatcgg aaaataacat
    50101 agtagagacg agctcctaaa atagccaagg gaaaggctac taagataaaa tctaaaatat
    50161 cgtctggtat gatcttcttt ctaggtgctt ctttcatggt caaataaacc gcaagaatca
    50221 agcctgtcac aatacataag gcataccaac gaatggctag gggtcctagt tgaatagcaa
    50281 ttggatcaag cattttgcac ctcatttcga gcgattagac ttgtcagtcg ttcgtcgaac
    50341 aaacgggtcg catcaaagcc catttccttg gcacgataat tcatggcagc tgcctcaatc
    50401 acaacagaga tattacgacc tgttttaact ggaatacgaa tacgaggaat ggctacgcca
    50461 gaaacttcaa gttcctctgc attatttcca agacgatcaa aggtcttatg cgtatcgtaa
    50521 ttttccaaat agacagcaag ctgaacctgt gaagaatcct tgacagcact cgcaccgtag
    50581 agactcataa catcgataat accaacccca cgaatttcaa tcaagtgttt caaaatttca
    50641 gctggttcac cccagagagt aatctcatcc ttggcaaaga tatcgacacg gtcatcggct
    50701 accaaacggt gaccacgttt gacaagctca agacctgtct cgctcttacc aattccacta
    50761 tctccctgaa tcaagacgcc catcccataa atatccatca agacaccgtg cacactggta
    50821 cgttctgcca aacgagaatc cagatagcta gataactctc caaataaacg actggtagct
    50881 gcacggctgg ttaaaatagc aatcttacat tctctagcag cctttaacat ctcctctgga
    50941 accaccaaac cacgggcaac aatgactgct ggtgtctcag gtagaaacat ttttttcaaa
    51001 acttcataac ggctgttgga aggcatgctg atcagataag accactcctt catccccaaa
    51061 agttgaatcc gctctggtgt atagtagtca aaatagcctg tcatttcaag accaggtcgc
    51121 gtaatatccg ctgtattgat ttccttttca agcaattctg gttcaccata gacaatgtct
    51181 agtctaagct tttcaatcac ttcttttact aaaaccgaca tcatttcctc cttcaaatga
    51241 gttcttctct ctattatatc aaattgtagg aggaagtttc agatttttgc aggctttgga
    51301 gtatttattt aaaagaaaaa ggactagatt tctctagcct ttcatttcaa ttagaatttt
    51361 ttacgtttac gagctacttc tgatttacgt ttacgtttta cagaaggttt ttcatagaat
    51421 tcacgtttgc gtgtttcttg aagagtacca gctttagtaa ccgcacgttt gaaacggcga
    51481 agtgcgtcgt caagagattc attcttacgt actactgttt tagacatttt tttcactccc
    51541 ttcaagttca agatctattc tattttacac gtaaaaggaa taattgtcaa gcaaaaatgc
    51601 ggtttaattt tgattttttc ttccatttat acaagagttg aaagcgttca atagaacatt
    51661 gcttttttat ttttagagta agctaagcgc ttcagcatct gcgatgatgg ttacatcagg
    51721 gtgattttgg aggctacttg caggtaggtt ctcagtcact gggccagata ctgttccggc
    51781 aatggcttct gctttcgact caccgtaagc aaaaagaata atagacttgg catccaaaat
    51841 gtttttaatc cccattgaaa tagcttgggt tgggacgtct tcaatcttgg caaagaagcg
    51901 tgcattggct tcgatagtag actggtcaag ttctactaga tgcgtttgac tgtcaaatgg
    51961 agtgccaggc tcattaaagc cgatatgccc attgcgaccg attcccaaga tttggaggtc
    52021 aactggatgg tcagccaaaa tttggttgta gcgttcaact tcagcttcag cattgtcctt
    52081 aacaccacga ggcaagaaac tttctttaaa tggtttttgg ttgaacaagt tttcttgcat
    52141 gaagtaacga taagactgtg gattgtcccc atcaaggccc acatactcat caaggttgac
    52201 actggttaga tttgaaaaat caaggtcact ctcaacaatt tccttgtaaa attcaagtgg
    52261 gctacttcct gtcgcaagtc ctagagtttg agctccatta gccaattttt ccttcaaaat
    52321 ctcaaaagca acttttccac cttgaacttg gttttcaact ttaataactt tcatcttttc
    52381 atcctccatt tttgtctata tttattatat ggtatagacc aatttttgtc aagtgaaaac
    52441 gatttaattt ctaaaaaaag agcgtccaaa cttgaaacgt gttataatgg ataggattag
    52501 aacttagaaa gaatgaacaa atatatgaat acagctgatt ttgatttcca cttgccagag
    52561 gaattgattg cccaaacgcc ccttgaaaaa cgtgatgcct ccaaactcct catcgtcaac
    52621 cgtgagacag gagaaatgca agataaacat ttccactcta ttattgatat gctggaacct
    52681 ggtgatgccc ttgtcatgaa cgacacccga gttctccctg cccgcctcta tggtcaaaaa
    52741 gtggagacag gaggtcatgt ggaacttctc ctccttaaga acactagtgg agacgagtgg
    52801 gaagttctgg ctaaacctgc caaacgcctc aaggtcggta ctcgtatcag ctttggtgat
    52861 ggccgcctca gcgctgtcgt tacagaagaa ttgacccacg ggggacgcat tgtccgcttt
    52921 gaataccaag gaattttcct agaagtcttg gaaagtctgg gagaaatgcc tctgccacct
    52981 tatatccacg aaaaattaga tgaccgtgaa cgttatcaaa ccgtctacgc caaggaaagt
    53041 ggctctgctg cagcaccgac tgctggtctt cacttcacca aagaactgct ggcagaaatc
    53101 caagctaagg gtgttcatct agtctatctg actctccatg tcggactcgg aacctttaga
    53161 cctgtttctg tggataatct ggacgaacac gaaatgcact cagagttcta tcaactttct
    53221 gaggaagctg ctgccaccct tcgctctgtc aaaaaaaatg gtggtcgtgt catcgctgtc
    53281 ggaaccactt ctatccgcac cttggaaact attggttcca agtttgatgg gcaaatccaa
    53341 gcagattctg gttggaccaa tatctttatc aaacctgggt atgagtggaa ggtcgtggat
    53401 gccttctcaa ccaacttcca cctgccaaaa tcaactctgg tcatgttggt ttctgccttt
    53461 gcaggccgtg aattagtctt agatgcctac caccattcca tccaagaaca ctaccgcttc
    53521 ttcagttttg gtgacgccat gtttatttat tgagaaagaa tttctctaaa tcttctaata
    53581 ccaataaatc gctaagatat tatttcaaag aacatctaca attgaaactc tagctagctg
    53641 tagaagaggc ctagtacatt gaaattaaaa tgcttccccc tagcttcgaa aatattgcca
    53701 tagattgcgt tgactctcca aattgattca tctatatttt atttcagctt cctatacttt
    53761 cttcgctgtt tgtaaatcaa aatgcaagac acatgagtag caccatattt gttactctta
    53821 tctgtcctct caagagacta ttatgagtta tttcagaatc attcactact ttgaccctga
    53881 ctctccttag tctcaaaatc aaagacttat actcttcaaa aatctcttca aaccgcgtca
    53941 acgtcacctt ggattatata tgtgactgac ttcgtcagtt ctatctacaa cctcaaagca
    54001 gtactttgag caacctgcga ctagttttct agtttgctct ttgattttca ttgagtatta
    54061 aacaaaaagt gaacaaatct gaattctaat gtacagaaga ctaggcttgt tcactttttt
    54121 atagtcgcta taagatgacc ttatctatag ctttttatat ataattatat attcagacat
    54181 actattatca attttgtcgc agggaggaat ctgttaacgc acccattcac cattatcatt
    54241 gactctatag ccatctatac ttgtattgac cgctaactca cccgatgtat ttacataata
    54301 ccatttacca ccaacttgga accattgatt gactttcata gaaccgttgc tgttgaggta
    54361 gtaccatgaa ctattaactt gtacccaacc tgttgccatg gaaccatcag tattataaaa
    54421 ataccacata ccattttctt gtttccagtc tgttgttgga gcaactgctt tagctggttc
    54481 tactgctaca tctgttcctt ggttagatgt aacagataca ggatacgaag gaatagatga
    54541 ttgctcagga acaacaactt tttcaggttc tctcgtccct ctccttatac gtctttttac
    54601 catctcttta gtaatttgac gagaagtagt ttcttcaatt gttccatcac gttcatctac
    54661 agtatagatt gtagtaagag taatttacca atttctccta cttcttctac ttcttgactt
    54721 ttatcaagag ttgggccatc gagatattct gtttcgattg gaatttcttg gacaagaact
    54781 tggggcttgg ttcttttttt aacaactctt gtttgagagt cttttttttg acttaaagta
    54841 ctctcagtta cttgtccact ctttccatct acattataag ttatcgttgt aactgttttc
    54901 ccattctttc ctagagtaat ctcttgctcc tgtcctgcag aaaggtcatt gtctgcttca
    54961 tatttagtag caaatggaac aagaacttct tcaaccttgc ttttagctgg aactttgata
    55021 actgtatccg tggcttcttt tctatcaaca gtaacctgtt cggtaacata accagtctct
    55081 ggattaacat cgtaggtcct tgtcgtagtt acatagccat cctctccatc aattgtaaca
    55141 ggattttcac tacggtcttt tgtttcatct ttttcataac gaattcgcgt acttgaaatt
    55201 ttcttggtta ctaccttagg tttagtcgct acttttacaa taatatcccc attgtcagcg
    55261 tcatcatact ctattccctc ttctttatct ctagtatcat ctctgacata ttgaatccca
    55321 tcagcagcat gaacaaaact tgtattcaga ttcctcctaa aaataaagtt agcccgatta
    55381 ccgcagaacc aaaaatcttt ccgagtttac gtattgcata gcgcttatta gtattagatt
    55441 ttgccattac atcctacttc tagtatagca tcttttctat caaacgttaa acaatatact
    55501 ttatatataa aatagactta gaatgatata ttgattattg aactaacact ttaactatat
    55561 cgtaatcaat ctcatatata aaggattgca gacatcttat ctaaatacat gctaatatat
    55621 ttagatacaa acattccaac ttgataattt tcactcatct ttcatcattc cttatacaac
    55681 tatgcagtat aaatagaata gttttctcat cagaatgaga ctattttaat att
//
LOCUS       DAVFER010000009        55476 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1105170250
            SAMEA2167659-rid19724873.denovo.009, whole genome shotgun sequence.
ACCESSION   DAVFER010000009 DAVFER010000000
VERSION     DAVFER010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2167659
            Sequence Read Archive: ERR388902
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 55476)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 55476)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928716.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928716.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 04:07:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,118
            CDSs (total)                      :: 2,073
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 120
            CDSs (without protein)            :: 120
            Pseudo Genes (ambiguous residues) :: 0 of 120
            Pseudo Genes (frameshifted)       :: 67 of 120
            Pseudo Genes (incomplete)         :: 47 of 120
            Pseudo Genes (internal stop)      :: 34 of 120
            Pseudo Genes (multiple problems)  :: 23 of 120
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..55476
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2167659-rid19724873.denovo.009"
                     /strain="1105170250"
                     /db_xref="taxon:1313"
     gene            complement(688..1689)
                     /locus_tag="VU534_000542"
     CDS             complement(688..1689)
                     /locus_tag="VU534_000542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000789954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEU1513175.1"
                     /translation="MKNINGKKVTIYDIARLSGFSPKTVSRVINGGVNVKEETYQAIQ
                     KVIEELSYIPNAYAKNLTKKEAINILISVKKIDSFPLIWFHTLLDKVLRTCKEFGVNA
                     IVEYFGEEDTISNSIISSTGSLVDGVIVFYESVDDIRIQYLKKNHMPFLVFGESQTSG
                     VVYVSNNNFQATYDMMKAVTEEKFKNMWLLMGGESHVNKDRERGVRSFLNDKNYFMDL
                     KVIYGLSTIDSVYSYAMQHLTTQNYPDIIFVSGDEKVQGLIRACYEKGILIPDDISII
                     GFDNIPISQYYTPALSTIAPNYVKLAKEMIEGVLAIIKGESVTSVEVSPKFVRRQSF"
     gene            complement(1797..2165)
                     /locus_tag="VU534_000543"
     CDS             complement(1797..2165)
                     /locus_tag="VU534_000543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1513176.1"
                     /translation="MKDYKINFDLGKIEYFDNNCLIQVYKFISFYDICEMVFAFHLPP
                     DELITNVIFKEKINSMLKCYIDRLLYVFINPTHFTEKVNLQFYGSFFSYEFICREVGN
                     ILKNKGVKCNLNFFEGEEYL"
     gene            complement(2261..2971)
                     /locus_tag="VU534_000544"
     CDS             complement(2261..2971)
                     /locus_tag="VU534_000544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000127555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HEU1513177.1"
                     /translation="MTATSLGLSNIEIVVRIVLSVVIGSIIGLERGSKSQPAGIRTYS
                     IVCLAACLIMMTNEYVSYKFGTGDPTRLGAQVISGVGFLGAGTILITDKKKITGLTTA
                     AGIWASAGIGLAIGVGFYEGALLVAISVWGVISMFQPLKKYLQNRSKMIELYIVVKST
                     EAYNRVLVYCAENGIRMTDSRTAFGDVNSDRIEYFDVPDKKIASFITLELSGRFEHLR
                     LMEEIANIVGVIYVEEIS"
     gene            complement(2974..4665)
                     /locus_tag="VU534_000545"
     CDS             complement(2974..4665)
                     /locus_tag="VU534_000545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEU1513178.1"
                     /translation="MRHKLNLKDWLIRLGLIWFLVTFIIYPNFDLVVNVFVKGGEFSL
                     DAVHRVLKSQRALQSIMNSFKLAFSLIITVNVVGILCVLFTEYFDIKGAKILKLGYMT
                     SLIYGGVVLATGYKFVYGPYGLITKFLQNVIPSLDPNWFIGYGAVLFIMTFSGTANHT
                     LFLTNTIRSVDYHTIEAARNMGAKPFTVFRKVVLPTLIPTLFALTIMVFLSGLSAVAA
                     PMIVGGKEFQTINPMIITFAGMGNSRDLAALLAIILGIATTILLTIMNKIEKGGNYIS
                     ISKTKAPLKKQKIASKPWNIIAHIVAYGLFTVFMLPLIFIVLYSFTDPVAIQTGNLTL
                     SNFTLENYRLFFSNSAAFSPFLVSFIYSIIAATTATILAVVFARVVRKHKSRFDFLFE
                     YGALLPWLLPSTLLAVSLLFTFNQPQFLVLNQILVGSLVILLIAYIVVKIPFSYRMVR
                     AILFSVDDEMEDAARSMGASPFYTMMKVIIPFILPVVLSVIALNFNSLLTDFDLSVFL
                     YHPLAQPLGITIRSAGDETATSNAQALVFVYTIVLMIISGTVLYFTQRPGRKVRK"
     gene            complement(4677..5687)
                     /locus_tag="VU534_000546"
     CDS             complement(4677..5687)
                     /locus_tag="VU534_000546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU1513179.1"
                     /translation="MIKFDNIQIKYGDFVAIDNLNLDIHEGEFFTFLGPSGCGKSTTL
                     RALVGFLDPSSGSIEVNGTDVTHLEPEKRGIGIVFQSYALFPTMTVFDNIAFGLKVKK
                     VAPDVIKAKVSAVAAKIKISDQQLQRNVSELSGGQQQRVALARALVLEPKILCLDEPL
                     SNLDAKLRVDLRKELKRLQKELGITTLYVTHDQEEALTLSDRIAVFNNGYIEQVGTPV
                     EIYHNSQTEFVCDFIGDINVLTDETVHEVLLKNTSVFLEDKKGYIRLEKVRFNRETEQ
                     DFILKGTIIDVEFSGVTIHYTIKVSESQILNVTSIDSQAAIRSVGESVELFITPSDVL
                     QF"
     gene            complement(5790..6857)
                     /locus_tag="VU534_000547"
     CDS             complement(5790..6857)
                     /locus_tag="VU534_000547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEU1513180.1"
                     /translation="MKKMKVWSTVLATGVALTTLAACSGGSNSTTASSSEEKADKSQE
                     LVIYSNSVSNGRGDWLTAKAKEAGFNIKMVDIAGAQLADRVIAEKNNAVADMVFGIGA
                     VDSNKIRDQKLLVQYKPKWLDKIDQSLSDKDNYYNPVIVQPLVLIGAPDVKEMPKDWT
                     ELGSKYKGKYSISGLQGGTGRAILASILVRYLDDKGELGVSEKGWEVAKEYLKNAYTL
                     QKGESSIVKMLDKEDPIQYGMMWGSGALVGQKEQNVVFKVMTPEIGVPFVTEQTMVLS
                     TSKKQALAKEFIDWFGQSEIQVEYSKNFGSIPANKDALKDLPEDTKKFVDQVKPQNID
                     WEAVGKHLDEWVEKAELEYVQ"
     gene            complement(6882..7541)
                     /locus_tag="VU534_000548"
     CDS             complement(6882..7541)
                     /locus_tag="VU534_000548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000793810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1868 domain-containing protein"
                     /protein_id="HEU1513181.1"
                     /translation="MKNLTKIKFKENGEFNHFPGNTVVANLYTKQDLMEVVDIIQSRY
                     RELPFIDKFTLTPRNSIHMTVIELLCHENRETEFWSSNLPLDTPLQEIHDYFAKQLEI
                     FPLLDEEIHMRITEMGKQNILVEPADEASAKRLEEIRTYVSEKAGVCFPNHDRYQFHI
                     SIGYLRIPLTEEEEEEFTKVRAELTEILLEKIPTITVNRIDYTVFEDMRQFVPYHEKF
                     K"
     gene            complement(7721..8731)
                     /gene="galE"
                     /locus_tag="VU534_000549"
     CDS             complement(7721..8731)
                     /gene="galE"
                     /locus_tag="VU534_000549"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000996568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HEU1513182.1"
                     /translation="MAILVTGGAGYIGSHTVVELLNLGKEVIIVDNLSNSSILVLDRI
                     EAITGIRPVFYELDVCDKQALRKVFEQESIDAAIHFAGYKAVGESVQKPVMYYKNNIM
                     STLALVEVMSEFNVKKIVFSSSATVYGINNQSPLIETMQTSATNPYGYTKVMLEQILK
                     DVHVADSEWSIALLRYFNPIGAHESGLIGEDPSGIPNNLMPYIAQVAVGKLSELSVFG
                     NDYDTLDGTGVRDYIHVVDLAIGHIKALEKVSEKTDVYIYNLGSGEGTSVLQLVNTFE
                     SVNKIPIPYKIVPRRSGDVATCYANADKAYKELNWRTTKSIEDMCRDTWNWQSKNPNG
                     YN"
     gene            complement(8744..10219)
                     /gene="galT"
                     /locus_tag="VU534_000550"
     CDS             complement(8744..10219)
                     /gene="galT"
                     /locus_tag="VU534_000550"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000848801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HEU1513183.1"
                     /translation="MKTIIDNFVDRVIEYGMYNEIDKIYVKNRVLALIGEEGIDRISD
                     ENDLKQIKDYLVEIALKNGKIKDLIEEKECLGAELMNFIVPLPSRLNDIFWSSYDISP
                     QEAVEEFYKLSKDSDYIKTSAIAKNIEFRASTKYGELEITINLSKPEKDPKTIAAEKL
                     VKATNYPKCLLCMENEGYQGRINYPARSNHRIIRLKLGDEVWGFQYSPYSYFNEHAIF
                     LNSQHVPMAITSKTFEQLLEIVDILPGYFAGSNSDLPISGGSILSHNHYQGGKHIFPM
                     EKAKFESEFCFKDFEDVNAGIVKWPMSVIRLQSENKNRLLDLATKILNKWREYSDLEV
                     DIIAMTEDVPHHTVTPIARKVDGRYELDIVLRDNHTTEQYPDGVFHPHQDVQHIKKEN
                     IGLIEVMGLAILPPRLKPELEEVGKYLLGEDNAIADYHLEWADQLKEKYPRINKEEVN
                     SVVQHEAGQVFARVLEDAGVYKNTPSGHEAFMRFVKSVGIN"
     gene            complement(10232..10873)
                     /locus_tag="VU534_000551"
     CDS             complement(10232..10873)
                     /locus_tag="VU534_000551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000945326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate uptake regulator PhoU"
                     /protein_id="HEU1513184.1"
                     /translation="MLRLYLENEIIELSNNLETIWVSVLDKYEKLFEYLSNEERVELI
                     KEDLIINESVLNIDKKGYELICLQHPVSYDLRRIISVIKISTDIERIGDRIVEILKNL
                     QILQNNEILKKIISKIKILHEVIGLHMNRAISCYREEQSGCLDMVVIQKQNEIEELSI
                     NMEKKIMNYIFEDDGNVSEVISALDIIHHLDKIAHTTQAIYKWIMYRKYGNIN"
     gene            complement(10931..11143)
                     /locus_tag="VU534_000552"
     CDS             complement(10931..11143)
                     /locus_tag="VU534_000552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000344424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1513185.1"
                     /translation="MDERFLDHAIINQIDVTSEQIVLMSDGFYEFYQNNQNKTFEELI
                     KMRFNSSAIDPIYGKKDDASILVIDV"
     gene            complement(11474..11770)
                     /locus_tag="VU534_000553"
     CDS             complement(11474..11770)
                     /locus_tag="VU534_000553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1513186.1"
                     /translation="MVKINKICSIQGSSVENEDIVGSQNQYFWIIGGATDLYNSKEEI
                     GYSVSEVVHILSESLSVNCKESKTLKQIFETALLEVKDEIGLNSYKLTEYSKMK"
     gene            complement(11754..13913)
                     /gene="pfbA"
                     /locus_tag="VU534_000554"
     CDS             complement(11754..13913)
                     /gene="pfbA"
                     /locus_tag="VU534_000554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multi-ligand-binding adhesin PfbA"
                     /protein_id="HEU1513187.1"
                     /translation="MLKIVKKLEVLMKYFVPNEVFSIRKLKVGTCSVLLAISILGSQG
                     ILSDEVVTSSSPMATKESSNAITNDLDNSPTVNQNRSAEMIASNSTTNGLDNSLSVNS
                     ISSNGTIRSNSQLDNRTVESTVTSTNENKSYKEDVISDRIIKKEFEDTALSVKDYGAV
                     GDGIHDDRQAIQDAIDAAAQGLGGGNVYFPEGTYLVKEIVFLKSHTHLELNEKATILN
                     GINIKNHPSIVFMTGLFTDDGAQVEWGPTEDISYSGGTIDMNGALNEEGTKAKNLPLI
                     NSSGAFAIGNSNNVTIKNVTFKDSYQGHAIQIAGSKNVLVDNSRFLGQALPKTMKDGQ
                     IISKESIQIEPLTRKGFPYALNDDGKKSENVTIQNSYFGKSDKSGELVTAIGTHYQTL
                     STQNPSNIKIQNNHFDNMMYAGVRFTGFTDVLIKGNRFDKKVKGESVHYRESGAALVN
                     AYSYKNTKDLLDLNKQVVIAENIFNIADPKTKAIRVAKDSAEYLGKVSDITVTKNVIN
                     NNSKETEQPNIELLRVSDNLVVSENSIFGGKEGIVIEDSKGKITVLNNQFYNLSGKYI
                     SFIKSNANGKEPVIRDSDGNFNIVTENGLYKIVTNNLSDKNEKEKNKEEKQSNSNNVI
                     DSNQKNGEFNSSKDNRQMNDKIDNKQDNKTEEVNYKIVGDGRETENHINKSKEIVDVK
                     QKLPKTGSNKIMELFLTVTGIGLLLTLKGLKYYGKDK"
     gene            complement(15043..16269)
                     /locus_tag="VU534_000555"
     CDS             complement(15043..16269)
                     /locus_tag="VU534_000555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001134527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegT/DnrJ/EryC1/StrS aminotransferase family
                     protein"
                     /protein_id="HEU1513188.1"
                     /translation="MPNYNIPFSPPDITEAEITEVVDTLRSGWITTGPKTKELERRLS
                     LYTQTPKTVCLNSATAALELILRVLEVGPGDEVIVPAMTYTASCSVITHVGATPVMVD
                     IQADTFEMDYDLLEQAITEKTKVIIPVELAGIVCDYDRLFQVVEKKRDFFTASSKWQK
                     AFNRIVIVSDSAHALGSIYKGQPSGSIADFTSFSFHAVKNFTTAEGGSATWKANPVID
                     DEEMYKEFQILSLHGQTKDALAKMQLGSWEYDIVTPAYKCNMTDIMASLGLVQLDRYP
                     SLLQRRKDIVDRYDSGFAGSRIHPLAHKTETVESSRHLYITRVEGASLEERNLIIQEL
                     AKAGIASNVHYKPLPLLTAYKNLGFDMTNYPKAYAFFENEITLPLHTKLSDEEVDYII
                     ETFKTVSEKVLTLSKK"
     gene            complement(16312..17004)
                     /locus_tag="VU534_000556"
     CDS             complement(16312..17004)
                     /locus_tag="VU534_000556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000922225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HEU1513189.1"
                     /translation="MLKWEDLPVEMKSSEVESYYQLVSKRKGSLIFKRCLDWVLALVL
                     LVLTSPIFLILSIWIKLDSKGPVIYKQERVTQYNRRFKIWKFRTMVTDADKKGSLVTS
                     ANDSRITKVGNFIRRVRLDELPQLVNVLKGEMSFVGTRPEVPRYTEQYSPEMMATLLL
                     QAGITSPASINYKDEDTIISQMTEKGLSVDQAYVEHVLPEKMRYNLAYLREFSFFGDI
                     KIMFQTVFEVLK"
     gene            complement(17177..18928)
                     /locus_tag="VU534_000557"
     CDS             complement(17177..18928)
                     /locus_tag="VU534_000557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU1513190.1"
                     /translation="MQNKQEQWTVLKRLMSYLKPYGLLTFLALSFLLATTVIKSVIPL
                     VASHFIDQYLSNLNQLAVTVLLVYYGLYILQTVVQYVGNLLFARVSYSIVRDIRRDAF
                     ANMEKLGMSYFDKTPAGSIVSRLTNDTETISDMFSGILSSFISAVFIFLTTLYTMLVL
                     DFRLTALVLLFLPLIFLLVNLYRKKSVKIIEKTRSLLSDINSKLAENIEGIRIIQAFN
                     QEKRLQAEFDEINQEHLVYANRSVALDALFLRPAMSLLKLLGYAVLMAYFGYRGFSIG
                     ITVGTMYAFIQYINRLFDPLIEVTQNFSTLQTAMVSAGRVFALIDERTYEPLQENGQA
                     KVQEGNIRFEHVCFSYDGKHPILDDISFSVNKGETIAFVGHTGSGKSSIINVLMRFYE
                     FQSGRVLLDDVDIRDFSQEELRKNIGLVLQEPFLYHGTIKSNIAMYQETSDEQVQAAA
                     AFVDADSFIQELPQGYDSPVSERGSSFSTGQRQLLAFARTVASQPKILILDEATANID
                     SETESLVQASLAKMRQGRTTIAIAHRLSTIQDANCIYVLDKGRIIESGTHEELLALGG
                     TYHKMYSLQAGAMADTL"
     gene            complement(18918..20663)
                     /locus_tag="VU534_000558"
     CDS             complement(18918..20663)
                     /locus_tag="VU534_000558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEU1513191.1"
                     /translation="MSIIQKLWWFFKLEKRRYLVGIVALILVSVLNLIPPMVMGRVID
                     AITSGQLTQQDLLLSLFYLLLAAFGMYYLRYVWRMYILGTSYCLGQIMRSRLFKHFTK
                     MSSAFYQTYRTGDLMAHATNDINALTRLAGGGVMSAVDASITALVTLLTMLFSISWQM
                     TLVAILPLPFMAYTTSRLGRKTHKAFGESQAAFSELNNKVQESVSGIKVTKSFGYQAD
                     ELKSFQAVNELTFQKNLQTMKYDSLFDPMVLLFVGSSYVLTLLVGSLMVQEGQITVGN
                     LVTFISYLDMLVWPLLAIGFLFNTTQRGKVSYQRIENLLSQESPVQDPEFPLDGIENG
                     RLEYAIDSFAFENEETLTDIHFSLAKGQTLGLVGQTGSGKTSLIKLLLREYDVDKGAI
                     YLNGHDIRDYRLTDLRSLMGYVPQDQFLFATSILDNIRFGNPNLPLSAVEEATKLARV
                     YQDIVDMPQGFDTLIGEKGVSLSGGQKQRLAMSRAMILDPDILILDDSLSAVDAKTEY
                     AIIDNLKEMRKDKTTIITAHRLSAVVHADFILVLQNGQIIERGTHEDLLALDGWYAQT
                     YQSQQLEMKGEEDAE"
     gene            complement(20869..21246)
                     /locus_tag="VU534_000559"
     CDS             complement(20869..21246)
                     /locus_tag="VU534_000559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000825490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HEU1513192.1"
                     /translation="MKRLIDGKPTLLIKNGNIDPEACRSVGLSASDVSLKLRSQGIFQ
                     MKQVKRAVQEQNGQLIVVQMGDENPKYPVVTDGVIQVDVLESIGRSEEWLLDNLSKQG
                     HDNVANIFIAEYDKGAVTVVTYE"
     gene            complement(21318..21774)
                     /locus_tag="VU534_000560"
                     /pseudo
     CDS             complement(21318..21774)
                     /locus_tag="VU534_000560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730499.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3290 family protein"
     gene            21908..22735
                     /gene="xth"
                     /locus_tag="VU534_000561"
     CDS             21908..22735
                     /gene="xth"
                     /locus_tag="VU534_000561"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006596696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HEU1513193.1"
                     /translation="MKLISWNIDSLNAALTSDSARAKLSQEVLQTLVAENADIIAIQE
                     TKLSAKGPTKKHVEILEELFPGYENTWRSSQEPARKGYAGTMFLYKKELTPTISFPEI
                     GAPSTMDLEGRIITLEFDAFFVTQVYTPNAGDGLKRLEERQVWDAKYAEYLAELDKEK
                     PVLATGDYNVAHNEIDLANPASNRRSPGFTDEERAGFTNLLATGFTDTFRHVHGDVPE
                     RYTWWAQRSKTSKINNTGWRIDYWLTSNRIADKVTKSDMIDSGARQDHTPIVLEIDL"
     gene            22747..22890
                     /locus_tag="VU534_000562"
     CDS             22747..22890
                     /locus_tag="VU534_000562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HEU1513194.1"
                     /translation="MDYNAVIPELLVSNIEQSRSFYCGLLGFRIEYQRPEENFLFLLK
                     SVN"
     gene            23001..23129
                     /locus_tag="VU534_000563"
     CDS             23001..23129
                     /locus_tag="VU534_000563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000646799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-1-phosphate uridylyltransferase"
                     /protein_id="HEU1513195.1"
                     /translation="MKANYPIYRPLTKRKFRVSDPYIYPHKFAVLDPDGYFLRFSE"
     regulatory      23512..23607
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            23998..24579
                     /locus_tag="VU534_000564"
     CDS             23998..24579
                     /locus_tag="VU534_000564"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000770427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HEU1513196.1"
                     /translation="MKLLEERILKDGHILGDNILKVDSFLTHQVDFSLMREIGKVFAE
                     KFATTGITKVVTIEASGIAPAVFTAEALNVPMIFAKKAKNITMNEGILTAQVYSFTKQ
                     VTSTVSIAEKFLSPEDKVLIIDDFLANGQAAKGLIQIIEQAGATVQAIGIVIEKSFQD
                     GRDLLEKAGYPVLSLARLDCFENGQVVFKEADL"
     gene            24579..25841
                     /locus_tag="VU534_000565"
     CDS             24579..25841
                     /locus_tag="VU534_000565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001194492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine permease"
                     /protein_id="HEU1513197.1"
                     /translation="MQTQEKHSQAAVLGLQHLLAMYSGSILVPIMIATALGYSAEQLT
                     YLISTDIFMCGVATFLQLQLNKYFGIGLPVVLGVAFQSVAPLIMIGQSHGSGAMFGAL
                     IASGIYVVLVSGIFSKVANLFPSIVTGSVITTIGLTLIPVAIGNMGNNVPEPTGQSLL
                     LAAITVLIILLINIFTKGFIKSISILIGLVVGTAIAATMGLVDFSPVAVAPLVHVPTP
                     LYFGMPTFEISSIVMMCIIATVSMVESTGVYLALSDITKDPIDSTRLRNGYRAEGLAV
                     LLGGIFNTFPYTGFSQNVGLVKLSGIKKRLPIYYAAGFLVLLGLLPKFGALAQIIPSS
                     VLGGAMLVMFGFVSIQGMQILARVDFANNEHNFLIAAVSIAAGVGLNNSNLFVSMPTA
                     FQMFFSNGIVVASLLAIVLNAVLNHKKK"
     gene            complement(25891..26352)
                     /locus_tag="VU534_000566"
     CDS             complement(25891..26352)
                     /locus_tag="VU534_000566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein DpnD"
                     /protein_id="HEU1513198.1"
                     /translation="MKTKQLVASEEVYDFLKVIWPDYETESRYDNLSLIVCTLSDPDC
                     VRWLSENMKFGDEKQLALMKEKYGWEVGDKLPEWLHSSYHRLLLIGELLESNLKLKKY
                     TVEITETLSRLVSIEAENPDEAERLVREKYKSCEIVLDADDFQDYDTSIYE"
     gene            complement(26349..27113)
                     /locus_tag="VU534_000567"
     CDS             complement(26349..27113)
                     /locus_tag="VU534_000567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease"
                     /protein_id="HEU1513199.1"
                     /translation="MELHFNLELVETYKSNSQKARILTEDWVYRQSYCPNCGNNPLNH
                     FENNRPVADFYCNHCSEEFELKSKKGNFSLTINDGAYATMMKRVQADNNPNFFFLTYT
                     KNFEVNNFLVLPKQFVTPKSIIQRKPLAPTARRAGWIGCNIDLSQVPSKGRIFLVQDG
                     QVRDPEKVTKEFKQGLFLRKSSLSSRGWTIEILNCIDKIEGSEFTLEDMYRFESDLKN
                     IFVKNNHIKEKIRQQLQILRDKEIIEFKGRGKYRKL"
     gene            complement(27294..27698)
                     /locus_tag="VU534_000568"
     CDS             complement(27294..27698)
                     /locus_tag="VU534_000568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000651202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PaaI family thioesterase"
                     /protein_id="HEU1513200.1"
                     /translation="MKDFHFDAISAFENYEIEKMRDGHVVVTTKVVNSSLNYYGNAHG
                     GYLFTLCDQISGLVVISLGLDGVTLQSSINYLKAGKLDDVLTIKGECVHQGRTTCVMD
                     VDITNQEGRNVCKATFTMFVTGQRSEERRVRI"
     gene            complement(27768..29249)
                     /locus_tag="VU534_000569"
     CDS             complement(27768..29249)
                     /locus_tag="VU534_000569"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HEU1513201.1"
                     /translation="MTLVNKFVTHVISESSFEEMDRIYLTNRVLARVGEGVLEVETNL
                     DKLIDLKDQLVEEAVRLETIEDSQTAREILGAELMDLVTPCPSQVNRDFWATYAHSPE
                     QAIEDFYQLSQKNDYIKLKAIARNIAYRVPSDYGELEITINLSKPEKDPKEIVAAKLV
                     QASNYPQCQLCLENEGYHGRVNHPARSNHRIIRFEMVGQEWGFQYSPYAYFNEHCIFL
                     DGQHRPMAISRQSFERLLAIVDQFPGYFAGSNADLPIVGGSILTHDHYQGGRHVFPME
                     LAPLQKAFRFAGFEQVKAGIVKWPMSVLRLTSDSKEDLINLADKILQEWRQYSDPAVQ
                     ILAETDRTPHHTITPIARKRDGQFELDLVLRDNQTSAEYPDGIYHPHKDVQHIKKENI
                     GLIEVMGLAILPPRLKEEVEQVASYLVGEAVTVADYHQEWADQLKSQHPDLTDKEKAL
                     AIVKDSVGAIFARVLEDAGVYKQTEQGQTAFMRFVEQVGILLD"
     gene            complement(29268..30446)
                     /locus_tag="VU534_000570"
     CDS             complement(29268..30446)
                     /locus_tag="VU534_000570"
                     /EC_number="2.7.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="HEU1513202.1"
                     /translation="MAQHLTTEALRKDFLAVFGQEADQTFFSPGRINLIGEHTDYNGG
                     HVFPAAISLGTYGAARKRDDQVLRFYSANFEDKGIIEVPLADLKFEKEHNWTNYPKGV
                     LHFLQEAGHVIDKGFDFYVYGNIPNGAGLSSSASLELLTGVVAEHLFDLKLERLDLVK
                     IGKQTENNFIGVNSGIMDQFAIGMGADQRAIYLDTNTLEYDLVPLDLKDNVVVIMNTN
                     KRRELADSKYNERRAECEKAVEELQVSLDIQTLGELDEWAVDQYSYLIKDENRLKRAR
                     HAVLENQRTLKAQVALQAGDLETFGRLMNASHVSLEHDYEVTGLELDTLVHTAWAQEG
                     VLGARMTGAGFGGCAIALVQKDTVEAFKEAVGKHYEEVVGYAPSFYIAEVAGGTRVLD
                     "
     gene            30611..31618
                     /gene="galR"
                     /locus_tag="VU534_000571"
     CDS             30611..31618
                     /gene="galR"
                     /locus_tag="VU534_000571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000212522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator GalR"
                     /protein_id="HEU1513203.1"
                     /translation="MATLKDIAQLASVSIATVSRVLNRDQSLSVTEETRHRILTVAEE
                     LGYTKHLKTGESHKPKQKIAIIQWVSEQGELDDLYYYQIRLGIEKRAQELDYDILRYF
                     NDHPFTLSEEVIGILCIGKFSRAQISAFEEYQKPLVFLDSDTLSLGHTCIITDFYTAM
                     KQVVDYFLSQGMDRIGILTGLEETTDQEEIIQDKRLENFKNYSQARGIYHDELVFQGR
                     FTAQSGYDLMKEAIQSLGDQLPPAFFAASDSLAIGALRALQEAGISLPDRVSLISFND
                     TSLTKQVYPPLSSITVYTEEMGRAGMDILNKEVLHGRKIPSLTMLGTRLTLRESTLNQ
                     E"
     gene            complement(31664..32701)
                     /locus_tag="VU534_000572"
     CDS             complement(31664..32701)
                     /locus_tag="VU534_000572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000833740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HEU1513204.1"
                     /translation="MKSAVYTKAGQVGLASIERPQIIEADDVIIRVVRACVCGSDLWR
                     YRNPETKAGHKNSGHEAIGIVEEAGEAITTVKPGDFVIVPFTHGCGECDACLAGFDGS
                     CDNHIGNNLGGDFQAEYIRFHYANWALVKIPGQPSDYTEGMLKSLLTLADVMPTGYHA
                     ARVANVQKGDKVVVIGDGAVGQCAVIAAKMRGASQIILMSRHEDRQKMAMESGATAVV
                     AERGQEGITKVREILGGGADAALECVGTEAAIEQALGVLHNGGRMGFVGVPHYNNRAL
                     GSTFMQNISVAGGAASATTYDKQFLLKAVLDGDINPGRVFTSSYKLEDIDQAYKDMDE
                     RKTIKSMIVIE"
     gene            complement(32702..33055)
                     /locus_tag="VU534_000573"
     CDS             complement(32702..33055)
                     /locus_tag="VU534_000573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HEU1513205.1"
                     /translation="MNIKSASDLLGISADTIRYYERVGLVPPITRTATGIRDFQDQDI
                     EALEFIKCFRSAGVSVDSLVDYMSLYQKGDETREERLGILEEEKQKLEERLSQLQTAL
                     NRLNLKIKLYKEGKF"
     gene            complement(33299..34189)
                     /locus_tag="VU534_000574"
     CDS             complement(33299..34189)
                     /locus_tag="VU534_000574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000645104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HEU1513206.1"
                     /translation="MKAKYAVWVAFFLNLTYAIVEFIAGGVFGSSAVLADSVHDLGDA
                     IAIGISAFLETISNREEDNQYTLGYKRFSLLGALVTAVILVTGSVLVILENVTKILHP
                     QPVNDEGILWLGIIAITINLLASLVVGKGKTKNESILSLHFLEDTLGWVAVILMAIVL
                     RFTDWYILDPLLSLVISFFILSKALPRFWSTLKIFLDAVPEGLDIKQVKSGLERLDNV
                     ASLNQLNLWTMDALEKNAIVHVCLKEMEHMETCKESIRIFLKDCGFQNITIEIDADLE
                     THQTHKRKVCDLERSYEHQH"
     gene            34322..34858
                     /locus_tag="VU534_000575"
     CDS             34322..34858
                     /locus_tag="VU534_000575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEU1513207.1"
                     /translation="MTNIDRRISKTKKAIYQAFIQLLNAKGYEATTVQDIIDLADVGR
                     STFYCHYESKELLLDQLCRYLFHHLFEREQAISTEDYLAHLFLHFHKNQDHITSLLFS
                     KNDYFLRQLHKELEHHVYSVLADNLKEAHPNLPTSYLQHLVMSNFIETLTWWLKKGQD
                     FTDQEVVQFYLDLLIPKN"
     gene            complement(35025..35831)
                     /locus_tag="VU534_000576"
     CDS             complement(35025..35831)
                     /locus_tag="VU534_000576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide riboside transporter PnuC"
                     /protein_id="HEU1513208.1"
                     /translation="MHTYLQKKIENIKTTLGEMSGGYRRMVAAMADLGFSGTMKAIWD
                     DLFAHRSFAQWIYLLVLGSFPLWLELVYEHRIVDWIGMICSLTGIICVIFVSEGRASN
                     YLFGLINSVIYLILALQKGFYGEVLTTLYFTVMQPIGLLVWIYQAQFKKEKQEFVARK
                     LDGKGWTKYLSISVLWWLAFGFIYQSIGANRPYRDSITDATNGVGQILMTAVYREQWI
                     FWAATNVFSIYLWWGESLQIQGKYLIYLINSLVGWYQWSKAAKQNTDLLN"
     gene            complement(36176..37696)
                     /locus_tag="VU534_000577"
     CDS             complement(36176..37696)
                     /locus_tag="VU534_000577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
                     /protein_id="HEU1513209.1"
                     /translation="MTNLIATFQDRFSDWLTALSQHLQLSLLTLLLAILLAIPLAVFL
                     RYHEKLADWVLQIAGIFQTIPSLALLGLFIPLMGIGTLPALTALVIYAIFPILQNTIT
                     GLKGIDPNLQEAGIAFGMTRWERLKKFEIPLAMPVIMSGIRTAAVLIIGTATLAALIG
                     AGGLGSFILLGIDRNNASLILIGALSSAVLAIAFNFLLKVMEKAKLRTIFSGFALVAL
                     LLGLSYSPALLVQKEKENLVIAGKIGPEPEILANMYKLLIEENTSMTATVKPNFGKTS
                     FLYEALKKGDIDIYPEFTGTVTESLLQPSPKVSHEPEQVYQVARDGIAKQDHLAYLKP
                     MSYQNTYAVAVPKKIAQEYGLKTISDLKKVEGQLKAGFTLEFNDREDGNKGLQSMYGL
                     NLNVATIEPALRYQAIQSGDIQITDAYSTDAELERYDLQVLEDDKQLFPPYQGAPLMK
                     EALLKKHPELERVLNTLAGKITESQMSQLNYQVGVEGKSAKQVAKEFLQEQGLLKK"
     gene            complement(37689..38417)
                     /locus_tag="VU534_000578"
     CDS             complement(37689..38417)
                     /locus_tag="VU534_000578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU1513210.1"
                     /translation="MIEYKNVALRYTEKDVLRDVNLQIEDGEFMVLVGPSGSGKTTML
                     KMINRLLEPTDGNIYMDGKRIKDYDERELRLSTGYVLQAIALFPNLTVAENIALIPEM
                     KGWSKEEITKKTEELLAKVGLPVAEYGHRLPSELSGGEQQRVGIVRAMIGQPKIFLMD
                     EPFSALDAISRKQLQVLTKELHKEFGMTTIFVTHDTDEALKLADRIAVLQDGEIRQVA
                     NPETILKAPATDFVADLFGGSVHD"
     gene            complement(38432..39196)
                     /locus_tag="VU534_000579"
     CDS             complement(38432..39196)
                     /locus_tag="VU534_000579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000043863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="HEU1513211.1"
                     /translation="MSQQVKNAHNLYIHAIQDGRVAEAQAQSVGDTYIQHSTGVPDGK
                     EGFAAFFADFFERHPERQIKIVRTIEDGNLVFVHVHQYLNGGEAQWVTTDTFREDENG
                     CIVEHWDVIDYYRTPENDQLDQIFGDFEIKDLDKKAENKKLVRRFLTEIFQNGELEQW
                     SDYVADDLIQHNHDIGQGSAAYKNYVAEYSVTFDFVFQLLGQGNYVVSYGQTQIDGVA
                     YAQYDIFRLENGKIVEHWDNKEVMPKVEDLTNRGKF"
     gene            complement(39200..39643)
                     /locus_tag="VU534_000580"
     CDS             complement(39200..39643)
                     /locus_tag="VU534_000580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEU1513212.1"
                     /translation="MKDGHLLAHHIRLLNGRIFQKLLSQDPEALYRGEQGKILAVLWN
                     SETGCATATDIALATGLANNTLTTMIKKLEEQKLVIVSPCGKDKRKKYLVLTELGKSQ
                     KEVGHRVSQKLDTIFYKGFSEEEIHQFEGFQERILANLKEKGNEV"
     gene            complement(40325..40621)
                     /locus_tag="VU534_000581"
     CDS             complement(40325..40621)
                     /locus_tag="VU534_000581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000230158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HEU1513213.1"
                     /translation="MVEPNLESLIKDLYNHARHDLSEDLVAALLETTKKLPTTNEQLQ
                     AVRLSGLVNRELLLNPKHPAPELLNLARFVKREEAKYRGTATSALMYEELFKML"
     gene            complement(40643..41707)
                     /gene="pepA"
                     /locus_tag="VU534_000582"
     CDS             complement(40643..41707)
                     /gene="pepA"
                     /locus_tag="VU534_000582"
                     /EC_number="3.4.11.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl aminopeptidase"
                     /protein_id="HEU1513214.1"
                     /translation="MTTLFSKIKEVTELAAVSGHEAPVRAYLREKLTPHVDEVVTDGL
                     GGIFGIKHSEAVDAPRVLVASHMDEVGFMVSEIKPDGTFRVVEIGGWNPMVVSSQRFK
                     LLTRDGHEIPVISGSVPPHLTRGKGGPTMPAIADIVFDGGFADKAEAESFGIRPGDTI
                     VPDSSAILTANEKNIISKAWDNRYGVLMVSELAEALSGQKLGNELYLGSNVQEEVGLR
                     GAHTSTTKFDPEVFLAVDCSPAGDVYGGQGKIGDGTLIRFYDPGHLLLPGMKDFLLTT
                     AEEAGIKYQYYCGKGGTDAGAAHLKNGGVPSTTIGVCARYIHSHQTLYAMDDFLEAQA
                     FLQALVKKLDRSTVDLIKHY"
     gene            42108..42809
                     /gene="galE"
                     /locus_tag="VU534_000583"
     CDS             42108..42809
                     /gene="galE"
                     /locus_tag="VU534_000583"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HEU1513215.1"
                     /translation="MTKTILVTGGTSYIGSHTVKALLNAGYQVHVLDNLSTGNRAAVD
                     SRASFKELDVYDASALKAYLEENQIDAVLHCAGEIVVSESIENPSKYFTANVAGMNQV
                     LKVLSEVGIQKIMFSSTASLYGNNCIDKPVTEDTLLDPVNPYAETKLMGERMIYWMAN
                     RYDWKYVIFRYFNVAGAEMDASNGLRVKNPTHIIPNINKTALGQNDSLKIFGDDYDTR
                     DGSCIRDYIYVLDLA"
     gene            43232..44191
                     /locus_tag="VU534_000584"
     CDS             43232..44191
                     /locus_tag="VU534_000584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU1513216.1"
                     /translation="MKLSHYLIGLLLLLVFLSISIGTSDFSWGKLFDFDQQTWLLFQE
                     SRLPRTISILLTASSMSMAGLLMQTITQNQFAAPSTVGTTEAAKLGMVLSLFVFPSAS
                     LTHKMLFAFVSSIVFTLFFLAFMTIFTVKERWMLPLIGIIYSGIIGSVTEVIAYRFNL
                     VQSMTAWTQGSFSMIQTHQYEWLFLGLIILITVWKLSQTFTIMNLGKETSESLGISYS
                     LLEKLALFLVALTTSVTMITVGGLPFLGVIVPNLVRKRYGDNLSQTKLMVALVGANLV
                     LACDILSRVLIRPYELSVSLLLGIIGSLVFILLLWRGGRKDAD"
     gene            44181..45137
                     /locus_tag="VU534_000585"
     CDS             44181..45137
                     /locus_tag="VU534_000585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001193667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HEU1513217.1"
                     /translation="MQTKSKHTKLFWILIILAIGACLLYFWPITHLSAFAWKLRSQKI
                     IVYLLVAIATGISTISFQTLTENRFLTPSILGIESFYVLLQTLLLVFESKFLQLGKSP
                     ILEFLVLLLVQSLFFLALQGYLKTLMKQDLVFVLLICLALRSLFRNISTFLQVLMDPN
                     EYDKLQNSLFASFQHLNTSILAIGSLIILALTIFFFRKAVVLDVLHLQRETAQILGLD
                     VEKEQKELLWGIVLLTSTATALVGPMAFFGFILANLTYLIVKDYQHKLLFIVAILVGF
                     ISLTLGQALIERVFALEIRISMIIESVGGFLFFILLYRRSRQ"
     gene            45134..45886
                     /locus_tag="VU534_000586"
     CDS             45134..45886
                     /locus_tag="VU534_000586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000764290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEU1513218.1"
                     /translation="MKLENIDKSIQKQDILQGISLEVSPQKLTAFIGPNGAGKSTLLS
                     IMSRLTKKDQGVLSIKGREIESWNSQELAQELTILKQKINYQAKLTVEELVSFGRFPY
                     SRGRLRSEDWEKIRETLNYLELTNLKDRYINSLSGGQLQRVFIAMVLAQDTDFILLDE
                     PLNNLDIKQSVSMMQILRRLVEELGKTIIIVLHDINMASQYADEIVAFKDGQVFSKGR
                     TDQIMQADLLSQLYEIPITLADINDKKICIYS"
     gene            45982..46947
                     /locus_tag="VU534_000587"
     CDS             45982..46947
                     /locus_tag="VU534_000587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HEU1513219.1"
                     /translation="MKTSLKLYFTALVASFLLLLGACSTNSSTSQTETSSSAPTEVTI
                     KSSLDEVKLSKVPEKIVTFDLGAADTIRALGFEKNIVGMPTKTVPTYLKDLVGTVKNV
                     GSMKEPDLEAIAALEPDLIIASPRTQKFVDKFKEIAPTVLFQASKDDYWTSTKANIES
                     LASAFGETGTQKAKEELTKLDKSIQEVATKNESSDKKALAILLNEGKMAAFGAKSRFS
                     FLYQTLKFKPTDTKFEDSRHGQEVSFESVKEINPDILFVINRTLAIGGDNSSNDGVLE
                     NALIAETPAAKNGKIIQLTPDLWYLSGGGLESTKLMIEDIQKALK"
     gene            complement(47172..47414)
                     /gene="yidD"
                     /locus_tag="VU534_000588"
     CDS             complement(47172..47414)
                     /gene="yidD"
                     /locus_tag="VU534_000588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HEU1513220.1"
                     /translation="MKRILIAPVRFYQRFISPVFPPSCRFELTCSNYMIQAIEKHGFK
                     GVLMGLARILRCHPWSKTGKDPVPDRFSLKRNQEGE"
     gene            complement(47414..48136)
                     /locus_tag="VU534_000589"
     CDS             complement(47414..48136)
                     /locus_tag="VU534_000589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HEU1513221.1"
                     /translation="MRINKYIAHAGVASRRKAEELIKQGLVTVNGQVVRELATTIKSG
                     DKVEVEGQPIYNEEKVYYLLNKPRGVISSVTDDKGRKTVVDLLPNVKERIYPVGRLDW
                     DTSGVLILTNDGDFTDEMIHPRNEIDKVYVARVKGVANKDNLRPLTRGLEIDGKKTKP
                     AVYEILKVDPVKNRSVVQLTIHEGRNHQVKKMFEAVGLQVDKLSRTRFGHLDLTGLRP
                     GESRRLNKKEISQLHTMAVTKK"
     gene            complement(48123..48692)
                     /locus_tag="VU534_000590"
     CDS             complement(48123..48692)
                     /locus_tag="VU534_000590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein B"
                     /protein_id="HEU1513222.1"
                     /translation="MSTLAKIEALLFVAGEDGIRVRQLAELLSLPPTGIQQSLGKLAQ
                     KYEKDPDSSLALIETSGAYRLVTKPQFAEILKEYSKAPINQSLSRAALETLSIIAYKQ
                     PITRIEIDAIRGVNSSGALAKLQAFDLIKEDGKKEVLGRPNLYVTTDYFLDYMGINHL
                     EELPVIDELEIQAQESQLFGERIEEDENQ"
     gene            complement(48711..49439)
                     /locus_tag="VU534_000591"
     CDS             complement(48711..49439)
                     /locus_tag="VU534_000591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000351912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HEU1513223.1"
                     /translation="MDIKLKDFEGPLDLLLHLVSKYQMDIYDVPITEVIEQYLAYVST
                     LQAMRLEVTGEYMVMASQLMLIKSRKLLPKVAEVTDLGDDLEQDLLSQIEEYRKFKLL
                     GEHLEAKHQERAQYYSKAPTELIYEDAELVHDKTTIDLFLTFSNILAKKKEEFAQNHT
                     TILRDEYKIEDMMIIVKESLIGRDQLRLQDLFKEAQNVQEVITLFLATLELIKTQELI
                     LVQEESFGDIYLMEKKEESQVPQS"
     gene            complement(49439..50179)
                     /gene="xerD"
                     /locus_tag="VU534_000592"
     CDS             complement(49439..50179)
                     /gene="xerD"
                     /locus_tag="VU534_000592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HEU1513224.1"
                     /translation="MPMRDRISAFLEEKQGLSVNSKQSYKYDLEQFLDMVGERISETS
                     LKIYQAQLANLKISAQKRKISACNQFLYFLYQKGEVDSFYRLELAKQAEKKTEKPEIL
                     YLDSFWQESDHPEGRLLALLILEMGLLPSEILAIKVADINLDFQVLRISKASQQRIVT
                     IPTALLSELEPLMGQTYLFERGEKPYSRQWAFRQLESFVKEKGFPSLSAQVLREQFIL
                     RQIENKVDLYEIAKKLGLKTVLTLEKYR"
     gene            complement(50170..50631)
                     /locus_tag="VU534_000593"
     CDS             complement(50170..50631)
                     /locus_tag="VU534_000593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000560721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEU1513225.1"
                     /translation="MIAKEFETFLLGQEETFLTPAKNLAVLIDTHNADHATLLLSQMT
                     YTRVPVVTDEKQFVGTIGLRDIMAYQMEHDLSQEIMADTDIVHMTKTDVAVVSPDFTI
                     TEVLHKLVDESFLPVVDAEGIFQGIITRKSILKAVNALLHDFSKEYEIRCQ"
     gene            complement(50628..51149)
                     /locus_tag="VU534_000594"
     CDS             complement(50628..51149)
                     /locus_tag="VU534_000594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001118598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HEU1513226.1"
                     /translation="MAKQTIIVMSDSHGDSLIVEEVRDRYVGKVDAVFHNGDSELRPD
                     SPLWEGIRVVKGNMDFYAGYPERLVTELGSTKIIQTHGHLFDINFNFQKLDYWAQEEE
                     AAICLYGHLHVPSAWLEGKILFLNPGSISQPRGTIRECLYARVEIDDSYFKVDFLTRD
                     HEVYPGLSKEFSR"
     gene            complement(51125..52096)
                     /locus_tag="VU534_000595"
     CDS             complement(51125..52096)
                     /locus_tag="VU534_000595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000182414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-triphosphate diphosphatase"
                     /protein_id="HEU1513227.1"
                     /translation="MTNKIYEYKDDQDWYVGSYSIFGGVNSLSDYKTDFPLFEFSKIF
                     GDEEYGFPLSVTVLRYGSIYRLFSFVVDMLNQEMGRNLEVIQRHGALLLVENGQLLYV
                     ELPKEGVNVHDFFETSKVRETLLIATRNEGKTKEFRAIFDKLGYDVENLNDYPDLPEV
                     AETGMTFEENARLKAETISQLTGKMVLADDSGLKVDVLGGLPGVWSARFAGVGATDRE
                     NNAKLLHELAMVFELKDRSAQFHTTLVVASPNKESLVVEADWSGYINFEPKGENGFGY
                     DPLFLVGETGESSAELTLEEKNSQSHRALAVKKLLEVFPSWQSKPSL"
     gene            complement(52093..52887)
                     /gene="racE"
                     /locus_tag="VU534_000596"
     CDS             complement(52093..52887)
                     /gene="racE"
                     /locus_tag="VU534_000596"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000370386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HEU1513228.1"
                     /translation="MDNRPIGFLDSGVGGLTVVRELMRQLPHEEIVYIGDSARAPYGP
                     RPAEQIREYTWQLVNFLLTKDVKMIVIACNTATAVVWEEIKAQLDIPVLGVILPGASA
                     AIKSSQGGKIGVIGTPMTVQSDIYRQKIHDLDPDLQVESLACPKFAPLVESGALSTSV
                     TKKVVYETLRPLVGKVDSLILGCTHYPLLRPIIQNVMGPKVQLIDSGAECVRDISVLL
                     NYFEINRGRDAGPLHHRFYTTASSQSFAQIGEEWLEKEIHVEHVEL"
     gene            complement(53095..53343)
                     /locus_tag="VU534_000597"
     CDS             complement(53095..53343)
                     /locus_tag="VU534_000597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000364981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YneF family protein"
                     /protein_id="HEU1513229.1"
                     /translation="MDLLLAIVLIVLAFLGGALGGMYLVRKQIEKEFADNPRLNAEAV
                     RTLLSANGQKPSEAKVQQVYHQIIRQQKAALANNKKKK"
     gene            complement(53599..55224)
                     /gene="treC"
                     /locus_tag="VU534_000598"
     CDS             complement(53599..55224)
                     /gene="treC"
                     /locus_tag="VU534_000598"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HEU1513230.1"
                     /translation="MTLDKGKVVYQIYPKSYKDTTENGIGDFRGIIEKIPYLAKLGVD
                     MVWLNPFYPSPQRDNGYDISDYMAVDPLFGDMADFEKMVCVGKEHKIDFMLDMVLNHC
                     STEHEWFQKALAGDKYYQDFFFIQDQPTDWQSKFGGSAWTPFGDTGKYYLHLFDETQA
                     DLNWRNSNVRKELFKVVNFWRDKGVKGFRFDVINLIGKDEVSVDCPENEGKPAYTDKP
                     IVHNYLRMMNQATFGSDDSFMTVGEMSSTTMENCVLYSSPDRQELSMTFNFHHLKVDY
                     KDGQKWTLAPFDFEELKSLYHSWGKEMSDKDGWSALFWNNHDQPRALNRFVDIQNFRK
                     EGATMLAASIHLSRGTPYIYMGEEIGMIDPDYDSMADYVDVESLNAYQMLLEEGKSQQ
                     EAFQIIQAKSRDNSRIPMQWDASENAGFSTGTPWLKAGKSYKYINVENEIQGPIFTFY
                     QDLIRLRKEMPIISEGSYKPAFEDSKQVYAFERQFEDQKLLVLNNFYAKEVEIDLPAV
                     YQNGQILISNYEDAEVSEKILLKPYQTLAIYVN"
BASE COUNT        16584 a        12254 c         9706 g        16932 t
ORIGIN      
        1 tcgtcagttc tatccacaac ctcaaaacag tgttttgagc agcctgcggc tagtttccta
       61 gtttgctctt tgattttcat tgagtattac tagctttttt cgtattagtc cagccttttt
      121 gtttgctttt agtagtaggc atggagctgt agatagaact caagttcatc aaagcgactt
      181 aaggccctaa taaaagataa accaaacgac ggatagaaaa aagcccacac acagaatata
      241 cttccgtgtg agggcgttgg taacgcggtg ccacctcaat tataaaggga ctatcccttt
      301 acatctctgc cttgtttaac aacaagctgc actgtaaggt gtgcgcaccg aattttcatt
      361 gtttcaaatt cattttcaaa atcagcccac tttcactact tccaaccacc tattcacaat
      421 caccacaggc tccctgaaga tcaaaaatag ttacttttct gatttgttga acttatttta
      481 atactttgtt ttttctttgt caagactttt ttacgatttt tttgaaaata tcattcgaat
      541 atgaccatgt cttccttaga tcgaacatga acatgtccca cttcttagaa attggatcca
      601 actcaataga aactgaatgg aggctaaaca gaacttattt tagaacactc catcttttcc
      661 actaggattt tcaagaatta aacaatacta gaaactctgt ctcctaacaa atttaggaga
      721 aacttcaaca gatgtgacac tttccccttt aataattgct aaaacacctt ctatcatttc
      781 tttagccaat ttaacataat tgggagcaat tgtagacaaa gctggagtat aatactgaga
      841 aataggaata ttatcaaatc caatgataga aatatcatct ggaataagaa ttcctttctc
      901 atagcacgca cgaatcaagc cctgaacctt ttcatctcct gaaacaaaaa taatgtccgg
      961 ataattttgg gtagtcaagt gctgcattgc ataagaataa actgaatcaa ttgtagataa
     1021 gccataaatg acttttaaat ccataaagta atttttatca ttcagaaaag aacgcacacc
     1081 tctttcacga tccttattaa catgggattc tcctcccata agcaaccaca tatttttaaa
     1141 tttttcttca gttacagctt tcatcatatc ataagtagct tgaaaattat tattagatac
     1201 atagactact ccagacgttt gagattcacc gaaaacaaga aaaggcatat ggttcttctt
     1261 taaatactga attctgatat catctacact ttcataaaaa acaataacac catctactag
     1321 gctacctgtg cttgatataa ttgaattact aattgtatcc tcctctccaa agtactcaac
     1381 tatagcatta acaccaaatt ctttacacgt ccgtaacact ttatctaaca gcgtatgaaa
     1441 ccaaattaaa ggaaaagagt cgattttttt tacagaaatc aatatattta tagcttcttt
     1501 tttagttaaa ttttttgcat acgcatttgg aatatacgac aattcctcta taactttttg
     1561 aatcgcttga taagtttctt ctttaacatt tactccacca ttaataactc gtgaaactgt
     1621 ttttggagaa aaacctgata aacgtgcaat atcataaata gttacctttt tcccatttat
     1681 atttttcatt tcagtcctcc attacgaaca ttctaatatt actatacaat atttaatttt
     1741 ttttaacaag agaatttagt aaattattta agatccacaa attcacaaaa ttaattttac
     1801 aaatattctt ccccttcaaa aaagtttaaa ttgcatttca cacctttatt tttaagaatg
     1861 tttccaactt cacgacaaat aaattcatat gagaaaaaac tgccataaaa ttgtagatta
     1921 actttttcag taaaatgtgt aggatttata aaaacatata atagcctgtc aatgtaacat
     1981 tttaacatag agttaatttt ttctttaaag ataacatttg ttatcaactc atcaggaggt
     2041 aaatgaaagg caaacaccat ttcacaaata tcataaaaag aaataaattt gtatacttgt
     2101 atcaaacaat tattatcaaa atattctatt ttacctaaat caaaattgat tttataatct
     2161 ttcataaaaa cctctgagca aaaatctact caaaaattag atgattaaaa catctaaaaa
     2221 gcaaaaggac aaaaacatct gtccctttgt ttactaaatt tcagctaatt tcttcgacat
     2281 aaataacacc tacaatatta gcaatttctt ccatcagtcg aagatgttca aatctacctg
     2341 ataattccag agtaataaat gacgctattt ttttgtccgg aacatcaaag tattcaattc
     2401 tgtcagaatt aacatctcca aacgctgttc ttgaatcggt cattctgata ccattttctg
     2461 cacaataaac caatacacga ttataggctt ctgtagattt aaccactata tacaattcaa
     2521 tcattttaga acgattttgc agatattttt ttagtggttg gaacatggat atcacacccc
     2581 aaacagaaat ggctactaaa agagctccct cataaaaacc tactccaata gctaatccaa
     2641 ttcctgccga agcccaaatg cctgctgcag ttgtcagacc tgtaattttc tttttatctg
     2701 taataagaat cgttccagcg cctagaaaac ccacacctga tataacttga gctcctaatc
     2761 gtgtaggatc tcctgtccca aatttataag atacgtattc attcgtcatc ataatcaaac
     2821 atgcagctag acaaacaata ctataagttc ggatgcctgc aggctgggat ttgctccctc
     2881 tctctaaacc aattatacta ccaatgacta ctgataaaac aatcctgaca actatttcaa
     2941 tatttgataa cccaagacta gtggctgtca tgattatttc cttactttac gccccggtct
     3001 ttgtgtgaag tataataccg ttccagaaat aatcatcaga acaattgtat aaacaaatac
     3061 cagagcttgt gcattagatg ttgctgtttc atcacctgca gatcgaatcg taatacctaa
     3121 tggttgagct aggggatggt aaaggaatac agataagtcg aagtcagtta ataaagagtt
     3181 aaagtttaaa gcaataacag agagaacaac cggtaaaata aatggaatga taaccttcat
     3241 catagtataa aaaggtgaag cacccatact tcttgctgca tcttccatct catcatcaac
     3301 actaaataaa atagcacgta ccattctata agaaaatggg atttttacaa ctatatatgc
     3361 aataagtaga attaccaaac tacctaccaa aatctgattc aagacaagaa attgtggctg
     3421 attaaaagta aataataaac ttactgctaa aagtgtactt ggtagtaacc aaggaagtag
     3481 agcaccatat tcaaataaga aatcaaaacg agatttatgt tttctgacaa cacgagcaaa
     3541 tacaactgcg agaattgttg ctgttgtcgc agcaataata gaataaataa agctgaccaa
     3601 gaatggagag aatgccgcac tattactaaa gaataagcga taattttcta aagtaaagtt
     3661 tgataatgtt aagttacctg tttgaattgc aactggatct gtaaatgagt ataatactat
     3721 aaaaattagt ggaagcatga aaactgtgaa caatccatat gctacaatgt gagcaatgat
     3781 attccaaggc ttagacgcaa ttttttgttt tttaagaggc gctttagtct tagagataga
     3841 aatataattt ccaccttttt ctatcttatt catgatagta agcaaaattg tagttgcaat
     3901 acctaaaata attgcaagta gggcagctaa atcacgagaa ttccccatcc ctgcaaatgt
     3961 aataatcatt ggatttatag tttgaaattc tttaccacca acaatcatgg gtgctgctac
     4021 tgcagataaa ccactaagaa aaaccataat agtaagtgca aatagagttg gaattaaggt
     4081 tggtaacact acttttcgga aaacagtaaa tggttttgct cccatatttc gagcagcctc
     4141 aatagtgtga tagtcaacgc ttcgaattgt atttgttaaa aacaatgtat gattagcagt
     4201 tcctgaaaat gtcataatga ataagactgc accataccca ataaaccagt tagggtctaa
     4261 agaagggata acattttgta aaaattttgt aatcaatcca taaggaccat agacaaattt
     4321 atatccagtc gctaaaacca ctcctccata aattaaagag gtcatataac ctaattttaa
     4381 aattttagca cctttaatat caaagtactc tgtaaataga acacaaagaa tacctacgac
     4441 attaactgta ataatgagtg aaaatgctaa cttaaaactg ttcataatac tctgaagtgc
     4501 cctctgagat tttagaacac gatgtacagc atcaagggaa aattctcctc cttttacaaa
     4561 tacattcact actagatcaa agtttggata aataataaat gttactaaga accagattaa
     4621 ccctaaacga ataagccaat cttttaaatt taatttatga cgcatactgc acctccttaa
     4681 aattgcagaa cgtctgatgg tgtgataaat aattccacac tttctccgac agatctaata
     4741 gcagcctgac tatcaatact tgttacatta agaatctgac tttcagaaac ttttattgta
     4801 tagtgaattg taactccaga aaactcaaca tcaataattg tcccttttag aataaaatct
     4861 tgttcagttt cacgattgaa tcgaactttc tctaatcgaa tgtatccttt tttatcctct
     4921 aagaaaacgc ttgtattttt caataatact tcgtggactg tttcatcggt caaaacatta
     4981 atatctccaa taaaatcaca tacaaattca gtttgagaat tatgataaat ctctactggt
     5041 gtaccgacct gttcgatgta tccattgtta aagactgcaa ttctatcaga taaagtcaag
     5101 gcttcctctt gatcatgagt aacatataaa gtagtaatac ctaactcttt ttgaagtctt
     5161 ttcaactctt ttctcaaatc tacacgtaat tttgcgtcaa ggtttgacaa tggttcatct
     5221 agacaaagaa ttttaggttc aagaaccaga gcacgagcca atgctaccct ttgttgttga
     5281 cccccagata attctgatac attacgctgt aactgttgat cagagatctt aatttttgct
     5341 gccactgctg atactttagc tttaataaca tctggagcta ccttcttaac ttttaaacca
     5401 aatgcaatat tatcaaaaac agtcatagtt ggaaatagcg cataagattg aaatacaata
     5461 ccaattccac gcttttcagg ttccaaatga gtgacatctg ttccattaac ttcaatactt
     5521 cctgatgatg gatctagaaa acctaccaat gctctcaaag tagttgattt accacatcct
     5581 gaaggcccaa gaaatgtaaa aaattcccct tcatgtatat ctaaattcag attatcaatt
     5641 gcaacaaaat caccatattt aatttgaata ttatcaaatt taatcatctc actaactccc
     5701 tctattacta aaccaaaagc ctctctttat ttcttccata aatttagaaa taatagagag
     5761 acttggacat aaaaattaac tcttatttct tattgtacgt attctaattc agctttttct
     5821 acccattcat ccaaatgctt tccaacagct tcccagtcaa tattttgtgg tttcacttga
     5881 tcaacaaatt tcttcgtatc ttcaggtaga tctttgaggg catctttatt tgcaggaata
     5941 gatccaaagt tcttactata ttctacttga atttctgatt gaccaaacca atcaataaat
     6001 tctttagcta acgcttgttt tttactagtg cttaaaacca tagtttgttc agttacaaat
     6061 ggtacaccaa tctcaggagt cataactttg aaaacaacat tttgttcttt ttgtccaact
     6121 aatgcaccag aaccccacat cattccatat tgtattggat cttctttgtc taacatctta
     6181 acaattgaac tttctccctt ttgaagagtg tatgcatttt tcaaatattc ttttgctact
     6241 tcccaacctt tttcggaaac acctaattca cctttatcat caaggtatcg aactaagata
     6301 cttgctagaa ttgcccgtcc tgtacctcct tgaagaccag aaattgaata tttaccttta
     6361 tacttactac ctaattcagt ccaatcttta ggcatttctt ttacatcagg cgccccaatt
     6421 aaaactaatg gttgaacaat cacaggatta taataattat ctttatctga taaagattga
     6481 tcaattttat ctaaccattt aggcttgtac tgtactagta atttttgatc tctaatttta
     6541 tttgaatcaa cagcaccaat tccaaatacc atatctgcaa ctgcattatt cttctcagca
     6601 ataacacggt ctgctaattg agcgccagcg atatcaacca tttttatatt aaaaccagct
     6661 tcttttgctt tagcagttaa ccaatcacca cgaccatttg agactgagtt cgaatagata
     6721 actaattctt gacttttatc agctttttct tcagatgaag aagcagtcgt agaatttgaa
     6781 cctccagagc aagcagcaag tgtagtaaga gcaactcccg ttgcaagtac agtagaccaa
     6841 actttcattt ttttcatgat aagttctcct tttttattat tttatttaaa tttttcgtga
     6901 tatggaacaa attgtctcat atcttcaaat acagtatagt caatacggtt tacagtaata
     6961 gttggaatct tctctaataa aatttcagtt aattctgctc tgactttagt aaactcttct
     7021 tcctcctctt cggttagagg aatccgaaga tacccaattg aaatatggaa ttgatatcta
     7081 tcatgattag ggaaacaaac acctgctttt tctgagacat aagtacgaat ttcttctaat
     7141 ctctttgcag aagcttcatc tgcaggttca actagtatgt tttgttttcc catttcagtt
     7201 atacgcatat gaatttcttc atccaacaat ggaaaaattt caagttgttt agcaaagtaa
     7261 tcatgtattt cctgtaaagg tgtatctaga ggaagattac tgctccaaaa ctccgtttca
     7321 cgattttcat ggcacaacaa ttcaattaca gtcatgtgaa tagaattcct tggagttaaa
     7381 gtaaacttat cgataaatgg taattctcta taacgtgatt gaataatatc aacaacttcc
     7441 atcaaatctt gtttagtata aagatttgct acaactgtat tcccagggaa atgattaaat
     7501 tccccattct ctttgaactt aatttttgtt aagtttttca tataaagacc ttctttttta
     7561 tatttgacat cggtgtcatc atgtttacat tatacaatga aaccgtttcc tttgtcaagc
     7621 acttgcaaac atttttttaa atttatcttt cattaaatat gcatttcatt aaaaggttaa
     7681 gtaatttttt caaaatacag cactcatata gacagtatca tcaattatag ccattgggat
     7741 tttttgattg ccaattccat gtatctctac acatgtcttc aatcgatttt gttgtcctcc
     7801 aatttaattc cttatatgct ttgtctgcat ttgcataaca agttgcaacg tctcctgaac
     7861 gtcttggaac tattttataa ggaataggga tcttattaac actttcaaat gtatttacaa
     7921 gttgtaatac actagtgcct tctcccgagc ctaggttata gatataaaca tctgtttttt
     7981 cagatacttt ttctaaagct tttatatgtc ctattgctaa atctactaca tggatataat
     8041 cacgcacacc agtaccatca agcgtatcat aatcatttcc gaacacactt agctctgata
     8101 gcttacctac cgctacttgt gcaatataag gcatcaagtt gttaggaatt cctgagggat
     8161 cttccccaat caaaccagac tcatgagcac caattggatt gaaataacga agcaacgcaa
     8221 tactccattc tgaatctgcc acatgaacat cttttaaaat ttgctcaagc atcactttcg
     8281 tatacccata aggatttgtc gcacttgttt gcatcgtctc aattagaggt gactgattgt
     8341 taattccata tacagtcgca cttgaagaaa agacaatctt tttaacatta aattctgaca
     8401 tcacttcaac aagtgccaat gtactcataa tattattttt gtagtacatc acaggctttt
     8461 gcacggattc tccgacagct ttataacctg caaaatgaat tgcagcatca atcgattctt
     8521 gttcaaatac ctttctcaat gcttgtttat cacaaacatc taattcgtaa aacacgggac
     8581 gtattcctgt aattgcttca atacggtcta gcaccaagat gctagagttc gaaaggttgt
     8641 cgacaatgat aacttccttt cctaaattta gtaattctac tacggtatgg ctaccaatat
     8701 aaccagctcc gcctgttacc aatattgcca tctgggtttc ctcctaatta attccaaccg
     8761 acttaacaaa tctcataaac gcttcatgcc cagacggtgt attcttataa actcctgcat
     8821 cttccagaac tctcgcaaac acttgtcctg cttcgtgttg aactacgcta ttaacctctt
     8881 ctttattaat gcgaggatat ttttctttca attggtcggc ccattctaaa tgataatccg
     8941 caattgcatt atcctctcct aaaagatatt ttccaacttc ttctaactct ggtttcaaac
     9001 gaggtggtaa tatcgcaagt cccatcactt cgattaaccc gatattttcc tttttaatat
     9061 gttgtacatc ttgatgagga tggaaaacac catctgggta ttgttcagta gtatgattat
     9121 ctcttagaac aatatctaat tcgtatctcc cgtccacttt acgagcaata ggagtcaccg
     9181 tatggtgtgg gacatcttca gtcatagcaa tgatgtctac ttctaaatct gaatattctc
     9241 tccacttatt tagaatttta gtagctaaat ctaacaagcg atttttattt tcactttgta
     9301 acctaattac tgacattggc cattttacaa taccagcatt aacatcctca aagtctttaa
     9361 aacaaaattc actctcaaat tttgcttttt ccattgggaa aatatgtttc cctccctggt
     9421 agtggttatg actaagaatg gagcctcctg agataggaag atcagaattt gaaccagcaa
     9481 aatatcctgg caaaatatca acaatctcca ataattgttc aaatgtttta gaggtaatag
     9541 ccattggtac atgttgacta ttcaaaaata tcgcatgctc attaaagtat gagtagggag
     9601 aatactggaa tccccatact tcgtcaccaa gtttcaaccg aataattcta tgattcgaac
     9661 gtgctggata atttattcgc ccctgatatc cttcattttc catacatagt aaacatttgg
     9721 gataattagt tgcttttact aatttttcag cagcaattgt ttttggatct ttttcgggtt
     9781 ttgacaaatt tatcgtaatc tctagctctc cgtatttagt tgatgctcga aactcaatat
     9841 tcttagcaat agcagaagtt ttaatataat cactatcttt acttaactta taaaactctt
     9901 caactgcttc ttgaggtgat atatcatatg aactccaaaa aatatcattt aatcgactag
     9961 gtaaaggaac tatgaaattc attaactctg ctcctaaaca ttccttttcc tcgattaaat
    10021 ctttaatttt accgtttttt aaggcgattt ccactaagta atcttttatt tgtttcaggt
    10081 cattttcatc ggaaatgcga tcaattccct cctcacctat taacgctagt actctatttt
    10141 tcacatatat tttgtcaatt tcattataca ttccgtattc aattactcta tcaacaaaat
    10201 tatcaataat tgttttcata tatttttctt tctaatttat gttcccatat tttctataca
    10261 ttatccattt ataaattgct tgcgtagtat gagcaatttt atcaaggtga tgaataatat
    10321 ctaaagcact aattacttca gaaacgttcc catcatcttc aaatatgtaa ttcattattt
    10381 tcttttccat atttatacta agctcttcta tctcattctg tttttgtata acaaccatat
    10441 ctaaacatcc agattgttcc tctctataac aagatatagc cctattcata tgcagtccga
    10501 taacttcatg aagtattttt atttttgaaa taattttctt caaaatttca ttattttgaa
    10561 gaatctgtag attttttaaa atttcaacaa ttctatcccc aatacgttca atgtcagttg
    10621 atatttttat tacactaata attcttctta agtcatatga aacaggatgt tgtaaacaaa
    10681 ttaactcata tcctttttta tcaatattta gaactgactc atttatgatt aaatcttctt
    10741 taatcaattc tactcgttct tcatttgata aatattcaaa taacttctca tatttatcaa
    10801 gcacagatac ccaaatggtc tctaaattat ttgataattc tataatttca ttttctaaat
    10861 ataaccttaa catttaggta cctcttctta acaaagttca atagtaacaa ttaatatttt
    10921 aaacaatata tcaaacatca atgactagaa tacttgcatc atccttcttt ccatagattg
    10981 gatcaatagc agaagaatta aatctcatct taattaactc ttcaaaagtt ttattttgat
    11041 tattttgata gaattcataa aagccatcgc tcattaaaac aatttgttca ctagtaacat
    11101 ctatttgatt aataatagca tggtctaaaa atctctcatc caacgaacct atccagtacc
    11161 cactcggttg attagataat tttctgattt tttgtaaaat aattttttta tttaaaacac
    11221 tatttgtacc aattgaatct tttatctcat ttttcccttt ttcaaataag ttatctactc
    11281 tatgatcagt tatttccatt tcgtttacta acatgacgca gtcacctagc atcatatact
    11341 ccaacttttt ttctgaaagt ttagcaaata ttggtaagcg ataatatagt atattgaaac
    11401 tagaatagta cacctctact tctaaaacat tgttagaaat cgatttgact gtcctgattg
    11461 atttgtccta ttattatttc attttactat actctgttaa tttatatgag tttaaaccga
    11521 tttcatcttt aacctcgagt aaagcagttt caaatatttg tttaagagtt tttgattctt
    11581 tacaattaac cgacaaactt tctgataaaa tatgtacaac ttctgagact gaataaccta
    11641 tctcctcttt agaattatat aaatctgtag ctccaccaat aatccaaaaa tactgatttt
    11701 gtgaacctac aatatcctca ttttctacgg aacttccttg tatcgaacaa attttattta
    11761 tctttaccat aatacttcaa cccttttagt gtcaaaagta aaccaattcc tgtcactgtt
    11821 aagaatagtt ccataatctt attcgaacca gtctttggta atttttgttt tacatctact
    11881 atttctttag atttattaat atgattttca gtttctctgc catctccaac tattttatag
    11941 tttacttctt ctgtcttatt atcttgttta ttgtcgatct tgtcattcat ttgtctatta
    12001 tctttacttg agttaaactc tccgttcttc tggttactat caattacatt atttgaatta
    12061 gattgttttt cctctttgtt tttttctttt tcgtttttat cacttaaatt atttgttaca
    12121 attttgtaaa gcccattctc cgttacaata ttgaaattac catcgctatc acgtataaca
    12181 ggttctttcc catttgcatt agatttgatg aatgatatat acttaccgga taaattataa
    12241 aattggttat ttaaaacggt tattttaccc tttgaatcct caataacaat tccttcttta
    12301 cccccgaata tactattctc tgagactact aaattatcac taactcgtaa taattcaata
    12361 tttggttgtt ctgtttcctt agaattatta ttaattacat tttttgttac agtaatatct
    12421 gatacttttc ctaaatattc tgcactatct tttgcaactc gtatcgcttt tgttttagga
    12481 tcggcaatat taaatatatt ttcggcgata accacctgtt tatttaaatc taataggtct
    12541 ttagtgtttt tatagctata agcatttact aaagctgctc cgctttctcg ataatgtaca
    12601 ctctctcctt taactttctt atcaaagcga tttcctttga ttaatacatc agtgaatcct
    12661 gtaaaacgta cacctgcata catcatgtta tcaaaatgat tattttgaat tttaatatta
    12721 gaggggttct gtgtcgacaa tgtttgatag tgtgtgccaa ttgctgttac taattcccca
    12781 gatttatcac ttttgccaaa ataggaattt tgaatagtca cattttcaga ttttttccca
    12841 tcatcattca aggcataagg aaaacctttt ctagttaatg gttcaatctg aatgctctcc
    12901 ttacttatga tttgcccatc cttcatcgtt ttgggtaagg cttgcccaag aaaacgagaa
    12961 ttatcaacta atacattttt cgaacctgca atttgaatag catgcccttg ataactatcc
    13021 ttgaatgtta cattttttat agttacgtta tttgaattcc caatagcaaa tgcacctgaa
    13081 gaatttataa gtggtagatt ttttgcttta gttccttctt cattcaaagc accgttcata
    13141 tcaatcgtac caccagaata actaatatct tctgttgggc cccattctac ttgcgcacca
    13201 tcatccgtaa ataaacctgt cataaaaaca atggaagggt gattcttaat atttatacca
    13261 tttagaattg tagctttctc attcaattct aagtgtgtat gactttttaa aaaaacaatt
    13321 tcttttacta aataagttcc ttcaggaaaa tatacatttc ctccacctag cccttgagct
    13381 gcagcatcta ttgcatcttg aattgcttgt cgatcatcat gaatcccatc acctaccgca
    13441 ccataatctt ttacacttaa agcagtatct tcaaattctt ttttgataat tctgtcactt
    13501 ataacatctt ccttataact cttattttca ttagtagatg ttactgtaga ttcaactgtt
    13561 ctgttgtcta attgtgaatt ggaacgaata gtaccattag agctgatact attaacactt
    13621 aacgaattat ctaaaccatt agtggttgaa ttagaggcaa tcatttcagc agaacgattc
    13681 tgattaacag ttggtgaatt atctaaatca ttagtaattg cattagaaga ctcttttgta
    13741 gccatcggtg aagaactagt aacaacttca tccgataaaa taccttggct tcccaaaatt
    13801 gaaattgcca atagtaccga gcaagtcccc acctttaatt tacgaatact gaatacctca
    13861 ttaggaacaa aatatttcat cagaacctcc aattttttta ctatttttaa caattgatta
    13921 ttacttttct taaaatagat agaatgacac cgctgtcatt atctttatca tatattttcc
    13981 aaattgaatt gtcaaggaat aacacaagaa aatattaaaa tttatactct tcggaaatct
    14041 cttcaaacta ggtcagtgcc gccttgccct aagtctaggt tactgacttg gtcagttcta
    14101 tagtagactg aaactaaaat agtacacctc tacttctaaa acattgttag aaatcgattt
    14161 gactgtcccg atcaatttgt cctattctca tttcatttta ctatatctac aacctcaaag
    14221 cagggttttg agctatctat ggccaacttc ctagtttgct ctttagcctt ccattcaaaa
    14281 gtgatgctat ctttcttagc ttgaatataa aatatcccat ttactatatt taaatttgtt
    14341 gatatgttgt aaattataaa tgaaagaaca aataccttgt catacaagca ttcgccaggg
    14401 atatttacct gaatatcgct catatggcgg attgaaacta aaacactaca atatatttct
    14461 taaatagacc ttctataaaa gctagattta acctcgataa aaatagatgc agtgcttcta
    14521 aaatactgga atagggcata taggtaatcg tagacaagtg ttttatagat tgtctcgcag
    14581 gagatctaat aatgtatagc aagcatcact aaacatatag aatatttgta ttattataat
    14641 atcaacatgc tataaattct atcatgcaaa agaatgacta gaacatgaaa gacaggcaca
    14701 aaattttgaa caatattctg aaaacaaaaa aagacgcgag tttccacaat ctcactcatg
    14761 gaaactcacg tctttcaaaa aatagggtga attgaaaact agaacaagac actagatttt
    14821 ctaaatgatg tctagtaagg attctaaatg ctacactaaa ttgctcacat cttatttcaa
    14881 accacgggac tcccacaaga aaggaaaatc ctataaaaat tctctctctg aggagaaagg
    14941 ggcctcaact acaggtgtaa actattatta attgaaaaca acagttttta cactcaatta
    15001 gactttttag gggcaggatc actttcgctt gactgtagtt tgtcattttt ttgataaagt
    15061 tagcactttt tcagaaactg ttttgaaagt ctcaatgata tagtctactt cttcatcgct
    15121 taatttagta tgaagaggga gggtaatttc attctcaaag aaggcatagg ccttaggata
    15181 gttcgtcata tcaaatccaa gattcttata ggctgtcaag agaggaagcg gtttgtagtg
    15241 aacattactt gcaattcctg ctttagccaa ttcttggatg atgaggttgc gttcttctag
    15301 gcttgctcct tctacacggg tgatgtagag gtggcgtgaa gattcgacag tttcagtctt
    15361 gtgtgccaaa ggatggatgc gagaacctgc aaaaccacta tcatagcggt ccacaatgtc
    15421 cttacggcgt tgcaacaaac ttggatagcg gtccaattgt accaaaccaa gtgaagccat
    15481 gatatcggtc atgttgcact tataggctgg tgtaacgata tcgtattccc atgaccccag
    15541 ttgcatcttg gcaagagcat ccttagtttg cccgtgaagg gaaaggattt ggaattcctt
    15601 gtacatctct tcgtcatcaa tcactggatt ggctttccaa gtcgcacttc caccttctgc
    15661 cgttgtaaag ttcttaactg catggaatga gaaggaagta aagtcagcga tagaaccaga
    15721 aggttgtcct ttataaatag atcccaaagc gtgggcacta tcagagacaa tgacaatacg
    15781 gttaaaggcc ttttgccact tgcttgaagc ggtaaagaag tcacgttttt tctccacgac
    15841 ttggaacaaa cggtcataat cgcaaacaat ccctgcgagc tctactggaa taatcacctt
    15901 agttttctca gtgatagctt gctcaagcag gtcatagtcc atctcaaacg tatctgcttg
    15961 gatatccacc atgacagggg ttgctcccac gtgcgtaatg acactacatg aagccgtata
    16021 ggtcatggct ggaacgatga cttcatcacc aggtcccact tccaaaacgc gtaaaatcaa
    16081 ctccagagcg gctgtcgcag agttgagaca aacagtctta ggtgtctgtg tgtaaagaga
    16141 caagcggcgc tccagttctt ttgttttagg acctgttgtg atccaaccag aacgcagggt
    16201 atccactact tcagtaattt ctgcttctgt gatatcaggc ggtgaaaatg gaatattgta
    16261 atttggcatt gatttgctcc ttttatctgt actcattttc ttatgactac tttattttag
    16321 tacctcaaac acggtttgaa acatgatttt gatgtcccca aagaaactaa actctcggag
    16381 ataggcgagg ttatagcgca tcttttcagg aagaacatgc tccacatagg cctgatcaac
    16441 tgacagacct ttctccgtca tttgactgat aattgtgtcc tcatccttgt agttgatgct
    16501 ggctggagag gtaatccctg cttgcaagag caaggttgcc atcatttcag ggctatactg
    16561 ctctgtataa cgtggcactt caggtcgtgt accgacaaag gacatctcac ctttaaggac
    16621 attgaccaac tgaggcagtt cgtccaaacg gacacgtcgg atgaaatttc caaccttggt
    16681 aatgcggcta tcgttagcag aagtcaccag acttcctttt ttatccgcat ccgtcaccat
    16741 ggtacgaaac ttccaaatct tgaaccgacg gttgtactgg gtcacacgct cttgcttgta
    16801 aatcactggc cctttgctat ccaacttgat ccaaatgctc aagatgagaa agatgggaga
    16861 ggtcagaacc agtaagacca aggccaaaac ccagtccaag caacgcttga aaatcagcga
    16921 acccttcctt ttagagacaa gctggtagta agactcaacc tcgcttgatt tcatttccac
    16981 aggcaagtct tcccatttca gcatgctgtt ctcctttgtt tttattatac tatttgtcaa
    17041 catttttcat tataccacaa aatggaaaag gcggtgaaag aaatctgtaa tttgaaggat
    17101 ttccttctag tactcaatga aaatcaaagt acagctttga gattgcagat aaagctgaca
    17161 tggtttaaag agattttcaa agagtatcgg ccatggcccc tgcctgcaaa ctatacatct
    17221 tgtgataggt tcctcccaga gccaagagtt cctcatgggt tccactctcg ataatgcgtc
    17281 ccttatccaa gacatagatg cagttggcat cttgaatagt agaaaggcgg tgagcgatag
    17341 caatagttgt tcggccctgt ctcatcttcg ccagagaagc ttgaaccaag ctttctgttt
    17401 cagagtcaat attggctgtc gcttcatcca aaatcaggat tttaggctgg ctggcgactg
    17461 ttctagcaaa ggcaagaagc tggcgttgcc cagtagagaa gctcgaacca cgctcggaaa
    17521 caggggagtc gtacccctga ggaagttctt gaataaagga atctgcatcc acaaaggctg
    17581 ccgcagcctg aacctgctca tcactggttt cttggtacat ggcgatattg gacttaatag
    17641 ttccatgata gaggaagggt tcctgcaaga ccaaaccgat gttttttctc agctcttctt
    17701 gactgaaatc cctgatatcc acatcatcca agagaactct ccctgactgg aattcataaa
    17761 agcgcatgag gacattgata atagacgatt tccctgaacc tgtatgacct acaaaggcaa
    17821 tggtttcacc cttattaaca gagaaagaaa tgtcatccag aatcggatgt ttaccgtcat
    17881 atgagaaaca cacatgttca aaacggatat tgccttcttg gactttggct tgcccatttt
    17941 cttgaagagg ttcataggtc ctctcgtcta tcagggcaaa gacacgacct gcagaaacca
    18001 tagccgtttg cagagttgaa aagttttgcg tcacctcaat caaggggtca aaaaggcggt
    18061 tgatgtactg gataaaggca tacatggtcc cgaccgttat cccgatagaa aaaccacggt
    18121 agccaaagta ggccatcaag actgcatagc ctagaagttt cagcaaactc atggcaggtc
    18181 tcaaaaagag ggcatccaag gctacagaac ggttggcgta gaccaagtgt tcttggttga
    18241 tttcatcaaa ttctgcctgc aggcgcttct cttgattaaa ggcctgaata atcctgattc
    18301 cctcgatatt ctctgccagc ttactattga tatctgacaa gagacttctg gttttctcga
    18361 tgattttcac tgactttttt cgatagagat tgaccaaaag gaaaatcaaa ggaagaaaga
    18421 gcaagactaa agccgtcaaa cgaaaatcca gcaccaacat ggtataaagg gttgtcagaa
    18481 agataaaaac tgctgagata aagctggata aaatcccaga aaacatatca ctaatcgtct
    18541 cggtatcgtt ggtcaaacga gaaacgatag aacctgctgg cgtcttgtca aagtaagaca
    18601 tgcccagttt ctccatattg gcaaaggcat cccgacgaat atccctaaca atactgtaag
    18661 acacgcgcgc aaagagaaga ttgccgacat actgaactac agtttgtagg atgtagagac
    18721 catagtagac cagcaaaacg gtaacggcta gttggttaag attgctgaga tactggtcga
    18781 taaagtggga agccacgagg ggtatgacac ttttaatgac cgtcgtcgct aggagaaaac
    18841 tgagtgccaa aaaggtcagg agtccataag gcttgagata agacatcaag cgcttcaata
    18901 cagtccattg ttcttgttta ttctgcatct tcttctcctt tcatttccaa ctgctgagac
    18961 tggtaggttt gggcatacca gccatccaaa gctagcaagt cttcgtgcgt gcctcgttcg
    19021 ataatttgac cattttgtag aactaaaata aaatctgcat ggacaacagc actgaggcga
    19081 tgggcagtga taatggttgt cttgtccttt cgcatctcct tgaggttgtc gataatcgca
    19141 tactctgtct tggcatctac ggcggataag gaatcatcca aaatcaagat atcagggtct
    19201 aaaatcatag cccgactcat agccaaccgt tgcttttgac caccagaaag actgactcct
    19261 ttttcaccaa tcagcgtatc aaatccttga ggcatgtcta caatatcttg gtaaacccgg
    19321 gctagcttag tagcttcctc gaccgctgaa aggggcaagt taggattgcc aaagcggata
    19381 ttgtctagga ttgaagtcgc aaaaagaaac tggtcctgag gaacatagcc catgagactg
    19441 cgaaggtctg tcagacgata gtcccgaata tcgtgaccgt ttagataaat ggcaccctta
    19501 tccacatcgt attcacgcaa gaggagcttg attaaggacg ttttcccaga gcctgtctgc
    19561 ccaaccaagc ccagtgtttg cccttttgcc aaactaaagt gaatatccgt cagtgtttcc
    19621 tcattttcaa aagcaaagct gtcaatggca tactccaaac gcccattttc aataccatcc
    19681 agaggaaact cagggtcttg tacaggagat tcctgagaca aaagattttc aatccgctgg
    19741 taagaaacct tccctcgctg agtagtatta aagaggaaac cgatggccag aagaggccag
    19801 accagcatat ccaaatagct gataaaggtg actagattcc caactgtaat ctgcccttcc
    19861 tgaaccatca aggagccaac caaaagcgtt aaaacatagg acgaaccaac aaacaagaga
    19921 accatagggt caaagagact atcatatttc atggtttgca ggttcttttg gaaggttaat
    19981 tcattgactg cctgaaaaga cttcaactcg tctgcctgat aaccgaaaga cttggtcact
    20041 ttgatacctg atacggactc ctgtaccttg ttattgagtt cagaaaaagc agcttgggat
    20101 tcgccaaagg ccttatgagt ctttctccct aggcgactag tcgtataggc catgaaaggt
    20161 agggggagaa tggcaacaag agtcatctgc catgagatgc taaagagcat ggtcaacaaa
    20221 gtcaccagag ccgtgataga ggcatccacc gcagacatga caccgccacc tgctaaacga
    20281 gtcaaggcat tgatatcatt ggttgcgtgt gccatcagat cacccgtccg ataggtttga
    20341 taaaaggctg acgacatttt tgtgaaatgc ttaaacaagc gagaccgcat gatctgtccc
    20401 aagcaataag aggtcccaag gatatacata cgccacacat agcgcaaata gtacatacca
    20461 aaggctgcaa gtagcaagta aaataggcta agaaggaggt cctgctgggt taattgcccc
    20521 gatgtgatgg catcaatgac ccgccccata accataggag gaatgagatt gaggacggaa
    20581 accaagatca gggccacaat tccgactaga taacggcgtt tttctaactt gaaaaaccac
    20641 caaagttttt gaataatgga cataaaatcc ctttctgatt gcaaatggaa acctgaggcc
    20701 aatactcaat gaaaatcaaa gagcaaacta ggaaactagc cgcaggctgc tcaaagcact
    20761 gctttgaggt tgtagataga actgacgaag tcagtaacct acatacggca aggcgacgtt
    20821 gacgcggttt gaagagattt tcgaagagta caagacccca ggtttttctt attcataagt
    20881 tacgactgta acagcaccct tgtcatattc agcaataaag atattggcta cattgtcatg
    20941 cccttgttta ctgaggttat caagcaacca ctcttcgcta cgaccaatcg attccaagac
    21001 atctacttga atcacaccgt cagtcacaac tggatactta ggattttcat ctcccatttg
    21061 cacaacgatg agttgcccat tttgctcttg cacagctcgt ttgacttgct tcatctggaa
    21121 aatcccttgg ctacgaagtt tgagggatac atccgatgca gacaaaccaa ctgaacgaca
    21181 ggcttctggg tcaatattcc catttttgat aaggagagtt ggcttaccat caatcaaacg
    21241 tttcacaaag tgaacattgt tgttgagcta tttgagagtc aagaccagtt tgattaaaat
    21301 ttcgatataa ttaagtgtca tttgttcaca tccaccagtt caattgcgtc tgtcttatac
    21361 aattcgactt tctctaacag gtacttgtct ggctcacttc catttagggc acgataatag
    21421 cgatctccca ccttgataag tgcgccatct gtgtttgtgg aagtattaac atagacttct
    21481 gacttgtcta ctcacaaatc tttggaaaca acctcgatga aatgaagtga agtttgaaat
    21541 ttattgttag aaacttgatt gttttgataa gtcgtgatgc tgaccaaaag cagagctaaa
    21601 taaggccaga tctgaaatca tgaccaactc acgaaattcg cttccctttt tattatggta
    21661 tgccttgaaa gcaaaaaaaa ctgtcacagc taatagaaca atcccaaagc caaccatgat
    21721 accattttgc tgaccgattt ggctgagtac atagtcataa gagtagaatt tcatgtattt
    21781 tcactccctt tcataaaatc attcttaatt ataaacgaaa gagagtaatt tttcaaacca
    21841 tacgttgggg aaatagatct ttttttggta taataaaatc tataatctga atgaaaaagg
    21901 taactttatg aaacttatct catggaatat tgattcccta aacgctgccc taactagtga
    21961 ctcagctcgt gccaaattgt cccaagaagt cctacaaacc ttggtcgctg aaaatgctga
    22021 tatcattgct atccaagaaa ccaagctttc tgccaaagga cctacaaaga aacacgtgga
    22081 aattttagaa gaactcttcc caggctacga aaacacgtgg cgctcttccc aagagcctgc
    22141 ccgtaaaggc tatgctggaa ccatgttcct ttataagaaa gaacttacac ctactatcag
    22201 cttcccagaa atcggtgccc cttctaccat ggacttggaa ggtcgtatca tcactctaga
    22261 atttgatgca tttttcgtaa cccaagttta cactccaaac gctggtgacg gtctcaaacg
    22321 cttggaagaa cgccaagtct gggatgccaa atatgctgag tatttggctg aactagacaa
    22381 agaaaaacca gtccttgcga ccggtgacta caacgtagcc cacaatgaaa tcgaccttgc
    22441 aaatcctgct agcaaccgcc gttcacctgg atttactgac gaggaacgtg ctggatttac
    22501 caaccttttg gcaactggat ttacagacac cttccgccat gttcatggcg atgttcctga
    22561 acgctacact tggtgggcac aacgcagcaa aacttctaaa atcaacaata caggctggag
    22621 aatcgactac tggctcacaa gtaaccgtat cgctgacaag gtcactaaat ctgatatgat
    22681 tgactcaggt gctcgccaag accatacacc gattgtcttg gaaattgact tgtaaggatt
    22741 ttctatatgg actacaatgc ggtcattccc gagttgcttg tatcgaatat cgaacagtcc
    22801 cggtccttct actgtggttt actgggtttt aggattgaat accaacgtcc agaagaaaac
    22861 tttctctttc tcttgaagag tgtcaactaa tgttagagga gggaacaaag gatcaactag
    22921 ctgaactgac ctatcccttt ggtcgtggag tcaatctctc ctttggcata aaggatgttt
    22981 caaaactcta ttaaagagtg atgaaggcaa actatcctat ttatcgtccc ttgaccaaaa
    23041 gaaagtttcg tgtcagtgat ccctatatct atcctcataa atttgcagtt ttggatccag
    23101 atggctattt tttaagattt agcgagtaga ataataaaaa ttgggaaaag tctttaaagt
    23161 tagaaaaagg catattgtca ggtgtctaaa agcttgatag tatgcctttt atgatggaaa
    23221 aatcttctaa tactcttcga aaatctcttc aagccacgtc aacgtcgcct taccgtaggt
    23281 atatgatact ggctctgtca attctatcca caacctcaaa acagtgtttt gaggttgtgg
    23341 atagcttcct agtttgctct ttgattttca tttagtataa ctgttagctt acaatggagt
    23401 ttttgttcac cctctcttct ttttgttcgt tttttaaacc aaaacactaa caaaatagtt
    23461 gatttctaaa gttatttagt gtaaaataaa aacattggct caagcctatt taaaattgaa
    23521 tatcgtttta cttgtttatg tcgtgaattg gcacgacgtt tctacaaggt gccggaacac
    23581 ctaacaataa gtaagtcagc agtgagatat ggccgttttt gccatgtcta tttaggggac
    23641 ttacttagag attaagtagg tcttttttta atatttccct taattagtgc ggacgggagg
    23701 tgaaattatc ctgtgaataa tttcaggaat ccagggaatt tcatccctaa tttttgagcc
    23761 cctagctctt tcatttctag gcttaggcta aaatagttcc ccgaactatt ttactctcaa
    23821 aaatcccgtc atagacaata acaagattat tgtctatgat accactacaa cgggaaatat
    23881 ttgataagac tcgcttcgct cgtaatagtt ttatcaaata tatagtatta gcaaaaggga
    23941 tcactataga aatatttaaa caacaagtaa attaactttt agactttagg aggtcttatg
    24001 aaattattag aagagcgcat cctcaaggat gggcatatct tgggtgataa catcctcaag
    24061 gtagattcct ttttaaccca ccaagttgac tttagcttga tgcgagagat tggtaaggtt
    24121 tttgcggaaa aatttgctac tactggcatt accaaggtcg taaccattga agcgtcgggt
    24181 attgccccag ccgtttttac agctgaagcc ttaaacgttc ccatgatttt cgccaaaaaa
    24241 gctaagaaca tcaccatgaa cgaaggcatc ttaactgctc aagtctactc ctttaccaag
    24301 caggtgacca gcaccgtttc tatcgctgaa aaattcctct caccagagga caaggttttg
    24361 attatcgacg atttccttgc taatggccaa gctgctaaag gcttgattca aatcatcgaa
    24421 caggccggtg ccacagtcca agctatcggt atcgtgattg agaaatcctt ccaagatggt
    24481 cgtgatttgc ttgaaaaagc aggctaccct gtcctatcac ttgctcgttt ggattgtttt
    24541 gaaaatggtc aagtcgtatt taaggaggca gatctctaat gcaaactcaa gaaaaacact
    24601 cgcaagcagc cgttcttggc ttgcagcact tactagccat gtactcagga tctatcctgg
    24661 ttcccatcat gattgcgaca gcccttggct attcagctga gcagttgacc tacctgattt
    24721 ctacagatat cttcatgtgt ggggtggcaa ccttcctcca actccaactc aacaaatact
    24781 ttgggattgg actcccagtc gttcttggag ttgcattcca gtcggtcgct cccttgatta
    24841 tgattgggca aagccatggt agtggcgcta tgtttggtgc ccttatcgca tctgggattt
    24901 acgtggttct tgtttcaggc atcttctcaa aagtagccaa tctcttccca tctatcgtaa
    24961 caggatctgt tattaccacg attggtttaa ccttgatccc tgtcgctatt ggaaatatgg
    25021 gaaataacgt tccagagcca actggtcaaa gtctcttgct tgcagctatt actgttctga
    25081 ttatcctctt gatcaacatc tttaccaaag gatttatcaa gtctatctct attttgattg
    25141 gtctggttgt tggaactgcc attgctgcta ctatgggctt ggtggacttc tctcctgttg
    25201 cggtagctcc acttgtccat gtcccaactc cactctactt tgggatgcca acctttgaaa
    25261 tctcatctat tgtcatgatg tgtatcatcg caacggtgtc tatggttgag tcaactggtg
    25321 tttatctggc cttgtctgat atcacaaagg atccaatcga cagcacgcgc cttcgcaacg
    25381 gataccgcgc agaaggtttg gccgtacttc tcggaggaat ctttaacacc ttcccttaca
    25441 ccggattttc acaaaacgtt ggtttggtta aattgtcagg catcaaaaaa cgcctgccaa
    25501 tctactacgc agctggtttc ctggttctcc ttggactgct tcctaagttt ggcgcccttg
    25561 cccaaatcat tccaagctcc gtcctcggtg gtgccatgct ggtaatgttt ggttttgtat
    25621 caattcaagg gatgcaaatc ctcgcccgtg ttgactttgc taacaatgaa cacaacttcc
    25681 ttatcgcagc tgtttcaatc gctgcaggtg tcggtctcaa caacagtaat ctctttgtca
    25741 gcatgccgac agccttccaa atgttcttct caaacggaat cgtcgtagcc agcctactcg
    25801 ctattgtcct caatgccgta ttaaatcata aaaagaaata agaaaaagag gtgcgagcct
    25861 cttttttgtt gacaaaataa aaacatctac ctattcatat atgctagtgt catagtcctg
    25921 aaaatcatct gcatcaagaa caatttcaca actcttatac ttttctctta caagtcgttc
    25981 ggcttcatct ggattttcag cctctatact tactaaacgt gataaagttt ctgtaatttc
    26041 tactgtatac tttttcagtt ttagattgct ttccaataat tcacctatta acaataatct
    26101 atgataggag ctatgtagcc actctggcaa tttatctcct acttcccacc catatttttc
    26161 cttcatcaaa gctagttgtt tttcgtcacc aaatttcata ttttcagata accatctcac
    26221 acaatcggga tctgataagg tacagacgat taaacttagg ttatcgtaac ggctttcagt
    26281 ttcataatca ggccagatga cttttaagaa atcatacacc tcttctgatg caacaagttg
    26341 tttcgttttc ataatttccg atactttcct ctacctttaa attctattat ttctttgtct
    26401 cttaatattt gaagctgttg cctaatcttt tctttgatat gattgttctt aacaaagata
    26461 ttttttaggt cactttcaaa acgatacata tcttcaaggg taaattctga accctctatc
    26521 ttatctatac aatttagaat ttctattgtc caacctcttg atgacagaga gctcttcctt
    26581 aaaaataaac cttgcttaaa ttcttttgta actttttctg gatctctaac ttgtccatct
    26641 tgcacaagaa atatccttcc tttagaaggt acttgtgata aatcaatgtt acaaccaatc
    26701 caacctgctc gtctagcagt tggtgcaagt ggttttcttt gaataatcga tttcggtgta
    26761 acaaattgct tcggaaggac aagaaagtta tttacctcaa aattttttgt gtaagttaaa
    26821 aaaaagaaat taggattatt atctgcctgc acacgcttca tcatcgttgc ataagcacca
    26881 tcattgattg ttaatgaaaa atttcctttt ttgctcttta gttcaaactc ctcactacaa
    26941 tgattacagt aaaaatctgc tacaggccga ttattttcaa aatgatttaa gggattgttc
    27001 ccacaattag ggcaataaga ctgacgataa acccaatcct ccgttaagat acgtgccttt
    27061 tggctattac ttttataggt ttctactaat tctaaattaa aatgtaattc catttaaaaa
    27121 ttcctcacta atatgagaac tcactcgata taagcaatta aaatctacta taactagtat
    27181 accacatata tgtacctatt acatttgtat ttcatcactc tcttttatat ttccttctaa
    27241 catatctcat aaattaaaaa tgagtgagat aaatttatcc cactcacctt tctttatatc
    27301 cttacccgtc tttcctcaga cctttggcct gtgacaaaca tggtaaaggt tgctttgcag
    27361 acatttctgc cctcttgatt ggtgatatcc acatccatta cacaagttgt acgaccttga
    27421 tggacacatt ctcctttaat ggtcaataca tcgtcgagtt ttcctgcctt aaggtagttg
    27481 atagaggatt ggagtgtcac cccatcaagt cccagcgaga taaccaccaa accactgatt
    27541 tggtcacata gcgtgaatag atagccacca tgggcattgc catagtagtt gagcgacgag
    27601 ttcactactt tggtcgtcac cacaacgtga ccatctctca ttttttcaat ttcgtaattt
    27661 tcaaaggcag atatagcgtc aaaatgaaag tctttcatcg tttcctcctg atatttcaaa
    27721 cgacactatg atactacttt ttataggact gtgcaaggag aaagctccta gtctagtaaa
    27781 attccgacct gttccacaaa gcgcataaag gctgtctgcc cttgttctgt ctgcttgtag
    27841 actcctgcat cctcaagtac acgcgcaaag atagcaccca cagagtcctt gacgattgca
    27901 agggcttttt ctttatccgt taggtctgga tgttgggatt tgagttggtc tgcccactcc
    27961 tgatgataat cggcaactgt aacagcttct cctacaagat agctagcgac ttgctccact
    28021 tcttctttca gacgtggtgg caagattgcc aagcccatga cctcaatcaa gccgatattt
    28081 tccttcttga tatgttggac atccttgtgg ggatgataga taccatcagg atactctgct
    28141 gaagtctgat tgtctcgcaa gaccaagtcc aactcaaact gtccatcgcg tttgcgggca
    28201 atgggtgtga tagtgtgatg cggtgtcctg tctgtctctg ccaaaatctg cactgcagga
    28261 tctgaatact ggcgccattc ctgcaaaatc ttatcagcca aattgatcaa atcctctttg
    28321 gaatccgaag tcaaacgtag gacagacatg ggccacttga caattccagc cttgacctgc
    28381 tcaaaaccag caaatcggaa ggccttttgc aagggagcca attccatagg aaatacgtga
    28441 cggcctccct gataatgatc atgagttaga atagagcccc ccacaatcgg caggtcggca
    28501 ttagatccag caaaatatcc tggaaactgg tctacgatag ccaacagacg ttcaaaactc
    28561 tgacgactaa tggccatggg acgatgctgg ccatctaaaa agatacaatg ctcattaaag
    28621 taagcatagg gcgaatactg gaaaccccat tcctgaccaa ccatttcaaa acggataata
    28681 cggtgattgc tacgagctgg gtggttaact cgaccatggt agccctcatt ctctagacaa
    28741 agctgacact gaggataatt actagcttgc accaacttgg ctgccacaat ctctttggga
    28801 tctttttcag gcttagagag attgatggta atttcaagtt ctccgtagtc agatggaaca
    28861 cgataagcga tatttctagc aatggccttg agtttgatgt agtcattttt ctgactgagt
    28921 tggtaaaaat cctctatcgc ttgttctgga gagtgggcgt aggttgccca aaaatcacga
    28981 ttgacctgac ttggacaagg agtcaccaaa tccatcagtt cagcaccaag gatttcacgc
    29041 gcagtctgac tatcctcaat cgtctctaat cgaacggctt cttcaaccag ctggtccttg
    29101 aggtcaatca atttatccag attggtctca acttccaaaa caccttctcc cactcgtgcc
    29161 aaaacacgat tggtcagata gattcgatcc atttcctcaa atgagctttc agaaatgaca
    29221 tgtgttacaa atttatttac taaggtcact atagagcctc cttttgacta gtcaaggacg
    29281 cgagtgccac ctgcaacttc agcgatatag aagcttggag cgtatccaac tacttcctcg
    29341 tagtgtttgc ctacagcttc cttaaaggcc tcaacagtat ctttttgaac caaggcaatg
    29401 gcacagccac caaaaccagc ccctgtcata cgagcaccga gaactccttc ttgtgcccaa
    29461 gctgtgtgaa caagggtatc caattccaaa ccagttactt cataatcatg ctccagagaa
    29521 acgtgtgacg cattcatcaa gcgtccaaat gtttccaaat ctcctgcttg gagtgctact
    29581 tgagctttga gggtacgttg gttttcaagc acagcatggc gagcacgttt caaacgattt
    29641 tcatctttaa tcagatagct atattggtca acggcccact cgtccaattc acccagagtc
    29701 tgaatatcca aggaaacttg caattcttcc actgcttttt cacactcagc acgacgttca
    29761 ttgtatttag agtccgccaa ttcacggcgt ttgttggtgt tcatgataac aacgacattg
    29821 tccttcaaat caagtggcac caagtcgtat tctaaagtat tagtatctag gtaaatagca
    29881 cgttggtctg cccccatacc aatagcaaac tggtccataa tgccagagtt tactccgata
    29941 aagttgtttt ctgtttgttt gccgatttta accaaatcga gacgctctaa ttttaaatca
    30001 aagagatgct cagccacgac tcctgtcaag agttccaagg atgcagaaga agacaagcca
    30061 gcaccatttg gaatatttcc ataaacataa aaatcaaaac ctttgtcaat cacgtgccca
    30121 gcttcttgca agaaatgaag gacacctttt ggataattgg tccagttgtg ctctttttca
    30181 aacttgaggt cagcgagagg cacttcgata atgcccttgt cctcaaagtt agctgagtag
    30241 aaacgcaaga cttggtcgtc acgcttacga gctgcaccgt aagttcccaa ggaaatagca
    30301 gcaggaaaaa cgtgcccacc gttgtagtct gtgtgttcac caatcaaatt aatgcggcct
    30361 ggtgaaaaga aggtttgatc tgcttcttga ccaaaaacag caagaaagtc tttgcgaagg
    30421 gcttcagtag taagatgttg tgccatatga attctccttt gactgtccgt taagccatct
    30481 taacgtgtaa tcgttttctt tctattatat ccaaggaatt ttccaaggtc aatccttttt
    30541 actaaaattt tagtaaaata tcagtaaaaa gaagaaaaac atgatatact aacctaatca
    30601 aggaggattt atggctacct taaaagacat tgcacagcta gcctctgtct ctatcgcgac
    30661 cgtatcccgc gtcctcaacc gcgaccagag cctatctgtt acagaagaaa ccagacaccg
    30721 tattttaacc gttgctgaag agctgggcta caccaagcac ctcaagacag gcgagtccca
    30781 caaacccaag caaaagattg ccattatcca atgggtcagc gaacaagggg agctggacga
    30841 cctctactac taccagattc gcctaggaat agaaaaaaga gcccaagagt tggactatga
    30901 tatcttgcgc tattttaatg accacccttt taccctaagc gaggaagtga ttgggattct
    30961 ctgcatcgga aagtttagtc gagctcagat ttctgccttt gaagaatacc aaaagcctct
    31021 tgtatttcta gacagcgata cactttccct gggacatacc tgtattatca cggattttta
    31081 cactgctatg aaacaggttg tcgattattt cctcagtcaa ggaatggacc gtatcgggat
    31141 tctaacaggc cttgaagaaa caacagacca agaagaaatc attcaggaca agcgtctaga
    31201 aaacttcaaa aactatagtc aagcgagggg aatctatcat gatgaactgg tctttcaagg
    31261 aagatttact gcccagtctg gctatgactt aatgaaggag gccattcaga gcttgggaga
    31321 ccaacttccg ccagcatttt tcgcagccag cgatagttta gctatcggtg ccctccgtgc
    31381 cctccaagaa gctggaatca gcctgccaga tcgcgtcagc ctcatttcct ttaacgacac
    31441 tagtctgacc aaacaggtct atcctcccct ctctagtatt acagtttata ctgaagaaat
    31501 gggccgagca ggtatggata ttcttaacaa ggaagtcctc cacggtcgga aaatccctag
    31561 cctgaccatg ctgggaacca gactgacatt aagagaaagt accctaaatc aagaatagga
    31621 taacataaaa aacgaataga gttctaaaac tcctattcgt tttttattcg attacaatca
    31681 tagacttaat tgtcttacgt tcatccatat ctttataggc ttggtcgata tcttccagtt
    31741 tataacttga agtaaagacg cgacctggat tgatatcacc atcaaggacg gcttttagta
    31801 aaaattgctt atcgtatgtt gtagcagaag ctgccccacc tgctacagag atattttgca
    31861 taaatgtcga accaagagca cgattattat agtgtgggac tcctacaaag cccatacgcc
    31921 ctccattatg aagaacacct agcgcctgtt ctatagcagc ctccgtacca acacattcaa
    31981 gtgctgcatc tgctcctcca ccgaggattt cacgcacctt ggtaattcct tcttgaccac
    32041 gttctgcaac aacagctgtc gcacctgact ccatagccat cttttgacgg tcttcatgac
    32101 ggctcataag gataatttgt gatgctccac gcatcttagc cgcgatgaca gcacattgac
    32161 caacagcccc atcaccgata acaacaacct tgtccccttt ttgaacattt gcaacacgcg
    32221 ccgcatgata gcctgtcggc atgacatctg caagagtcaa aagggacttg agcatccctt
    32281 ctgtatagtc agaaggttga ccagggattt taaccagcgc ccagtttgca tagtggaagc
    32341 gaatatattc tgcctgaaaa tcacccccca aattattgcc aatatgattg tcgcaagaac
    32401 cgtcaaatcc agcaagacag gcatcacact caccacatcc atgtgtaaaa gggacaatca
    32461 caaaatcacc tggtttcacc gtcgtaatgg cttccccagc ttcttcaaca atcccaatcg
    32521 cttcgtgtcc actatttttg tgtccagctt tcgtttctgg attacggtac ctccataaat
    32581 ctgaaccaca aacgcacgca cgaaccacac gaataatcac atcatccgct tctattattt
    32641 gcggacgttc aatgctagca agtccaacct gacctgcctt tgtatatact gctgatttca
    32701 tttaaaattt tccttcctta taaagtttaa ttttgagatt taaacgattt aaagctgtct
    32761 gtagctgaga caagcgctcc tctaattttt gcttttcctc ttctaaaata ccaagcctct
    32821 cctctctcgt ttcatctccc ttttggtaga gcgacatata gtcaactaaa ctatctacag
    32881 agacacccgc cgaacgaaaa cacttaataa attccagcgc ttcgatatcc tgatcttgaa
    32941 aatcacgaat cccagtagca gtacgagtaa tcggtggcac aagaccaacc cgttcataat
    33001 accgaatcgt atccgctgaa attcccaaca aatcactggc agatttaata ttcacacgct
    33061 aacctcctct catttcattc actgaattca cgctattcta actcacttat cttattatat
    33121 aactttgagt tgactccaag tcaagcattt tgtatctaat cgaaaaattt ttatcattaa
    33181 caatcatata tctggagttt atacaatgct cttctcttac caatttttga aatatttaaa
    33241 taataaagaa attactctat tccaaataag atagtaccca agtatttttc acttttttct
    33301 aatgttgatg ctcataactc cgttccaagt cacacacctt tcgcttatgg gtttggtgag
    33361 tttctaggtc agcatcaatt tcaatggtaa tattttgaaa accacaatct tttaggaaaa
    33421 ttcgaataga ctctttacaa gtttccatat gttccatttc ttttagacaa acatggacaa
    33481 tggcattttt ttccaaagca tccatagtcc agagattaag ctgattaagg ctggccacat
    33541 tgtccaatcg ctccaggcca ctctttactt gcttgatatc aagaccttct ggcacagcat
    33601 ccaagaaaat cttgagtgta gaccaaaaac gtggaagggc ttttgaaaga ataaagaaag
    33661 aaatgacaag ggacaaaaga ggatctagga tataccagtc cgtaaatcga agaacaatcg
    33721 ccatcaggat aacagctacc caccctagcg tatcttccag aaaatgcaga ctcagaatag
    33781 actcattctt tgtctttccc ttaccaacca ccagactcgc taacagattg atagtaatcg
    33841 caataattcc taaccagaga atcccctcat cattgactgg ttgcggatgc aaaatcttcg
    33901 tgacattttc caaaatgact agaacagagc ccgttacgag aatcacagct gttaccaagg
    33961 ctcctagcag gctaaaccgc ttatagccca aggtgtactg attgtcttct tcacgattgg
    34021 agattgtttc tagaaaagct gatattccaa ttgcaatcgc atctcccaag tcatgcacag
    34081 agtcagcaag aacagcgcta gaaccaaata ctccacctgc aataaactca acaatggcat
    34141 aagtcaaatt taagaaaaaa gccacccaaa cagcatattt tgccttcata tttctcattc
    34201 ctttgttata atagatttat gaacaccttg ttcattatca ttatccacta aaactcaaag
    34261 aaaggataga agcaaaacgt cagctttatt cagttctgaa caatttgcct taagtgtcca
    34321 tatgactaac attgaccgcc gtatcagcaa aaccaaaaaa gccatctatc aagcttttat
    34381 acaacttttg aatgctaagg gctacgaggc cactactgtt caggatatca ttgatctcgc
    34441 agatgtggga cgatccacct tttactgtca ctatgagagt aaggagcttc ttctggacca
    34501 gctctgccgc tacctcttcc atcatctttt tgaaagagag caagccattt caaccgagga
    34561 ctacctcgcc cacctctttc tccattttca taaaaaccaa gaccatatca ccagtctgct
    34621 attttccaaa aatgactact tcctccgtca actccataaa gagctagaac accatgtcta
    34681 ttccgtgcta gctgataatt taaaagaagc ccaccctaat ctgcctactt cttacctcca
    34741 acacttggtc atgtccaact ttatcgagac attgacctgg tggctcaaaa aaggtcaaga
    34801 tttcacagac caggaagttg tccaatttta tctagacctt ctcattccta aaaattgaat
    34861 atagagtaaa gcttcagttg tcttatttct aggttactga gttttttatc ttttcaacaa
    34921 caaaagagga cccgccgatc ctctttttca tactataaat ccttgattat caactatatc
    34981 tgttttaatc gaaatctcaa aacagcactt tcaaacatct tttcctagtt aagtaaatca
    35041 gtattctgct tagctgcctt gctccattga taccaaccaa ctagactgtt aatgagataa
    35101 attagatatt tcccttgaat ttgcaggctt tctccccacc agagatagat tgaaaagaca
    35161 ttggtagccg cccagaatat ccactgttca cggtaaacag ctgtcatgag gatttgccct
    35221 accccattgg ttgcatctgt gattgaatca cgatagggac gattggcacc aatagactga
    35281 taaatgaagc caaaggccaa ccaccaaagc acactaatgg aaagatactt tgtccagccc
    35341 ttgccgtcca gtttacgcgc gacaaactcc tgcttttcct tcttaaactg tgcctgataa
    35401 atccaaacta gaagtccaat tggctgcatg actgtgaagt aaagtgtcgt cagcacctca
    35461 ccataaaagc ctttctgtag ggccaaaata aggtaaataa cagagttaat caagccaaaa
    35521 agataattac ttgctcgacc ttccgataca aagattacac agataatccc tgtcaagcta
    35581 caaatcatcc caatccagtc aacaatacga tgttcgtaaa ccaactccag ccagagagga
    35641 aaacttccta aaaccagcaa ataaatccac tgggcaaaac tacgatgggc aaagaggtca
    35701 tcccagatag ccttcatagt tcctgaaaat cctaaatcag ccatagccgc aaccatacga
    35761 cggtaaccac ctgacatttc acctagggtt gttttgatat tttcaatttt cttttgcaaa
    35821 taagtatgca tcatttctcc ttttgttttt aaagagccgt gtctggatag actttcggac
    35881 gcaacgctct attagataat gaactgccta tacacaagat ttctaacctt agtcgacatg
    35941 agctgaaacc tcttatttgt taagtagttc acaaaatatt atacacctat tttatgaata
    36001 gtcaactgtc tttacagtaa aattttagaa aatcatgaaa attttctctt tctttccatt
    36061 ttaagtgaca ttcagtcatt ctcacatcaa aaaagcccag acgaaattgt ctgagcattc
    36121 ttttatctag tcgtttaagg aagttgagtt cagtatgttt aaagtctctg tcccatcatt
    36181 tcttcaacaa accttgttct tggagaaact ccttggctac ttgctttgct gacttgcctt
    36241 caacaccgac ttggtagttg agctggctca tctggctttc tgtaatctta ccagccaatg
    36301 tattaagaac tctttccaac tctgggtgtt tcttgagaag agcttctttc atgagtggag
    36361 ccccttgata aggtgggaag agttgcttgt catcttccaa gacctgtaaa tcataacgct
    36421 ccaattccgc atcagtcgaa taggcatccg tgatttgaat atcccctgac tgaatagcct
    36481 gatagcgaag ggctggctca atggtcgcta cattgagatt gagaccatac attgattgca
    36541 agcccttatt tccatcttca cggtcgttaa actcgagtgt aaaacctgcc ttcaactgcc
    36601 cttccacttt tttcaagtct gaaatggtct tcaagccata ttcttgagca atctttttcg
    36661 gaacagctac agcataggtg ttttgataag acatgggttt gagataggct agatgatcct
    36721 gcttagcaat gccatcacgc gccacctgat aaacctgttc tggttcatga ctcaccttgg
    36781 gtgatggttg aagcaaactt tcagtcaccg taccagtaaa ttcaggatag atgtcaatat
    36841 cgcctttttt cagagcttca taaaggaagc ttgtcttccc aaaattcggt ttaacagtcg
    36901 cagtcatgct ggtattttct tcaatcagca acttatacat attggccaaa atttctggtt
    36961 ctggacctat tttcccagca ataaccaagt tttccttctc tttttgaacc aaaagagctg
    37021 gactataaga cagacccagt aataaagcca ccaaggcaaa acctgagaaa atcgtccgta
    37081 attttgcttt ttccatcact tttagtagga agttaaaggc aatggctagc actgcagaag
    37141 aaagtgcccc aatcaaaatc aaactggcat tattacggtc aattcccaaa agaataaagg
    37201 aacctagtcc ccctgcacca atcaaggccg ccaaggttgc cgtaccgata atcaaaacag
    37261 ctgccgtccg aatcccagac atgataacag gcatggcgag tggaatttca aatttcttga
    37321 gacgttccca tctggtcatc ccaaaggcaa tcccagcctc ttgcaggttc ggatcaattc
    37381 ccttcagccc agtgatagta ttttgcaaaa tagggaaaat cgcataaatc actagagctg
    37441 tcaaagccgg caaggtccca attcccatca aagggataaa gagccccaac aaggccagag
    37501 acgggatggt ctggaaaata cctgcaatct gcaagaccca gtcggccagc ttctcatgat
    37561 agcgaagaaa aacagccaag ggaatcgcaa gcaaaatagc tagtaacaag gtcaaaagcg
    37621 acaactgcaa atgttgagat agagctgtca accaatcact aaaacgatcc tgaaaagttg
    37681 caattaaatt agtcatgaac actacctcca aacaagtctg ctacaaagtc tgttgcaggc
    37741 gcttttaaaa ttgtctcggg attcgctacc tggcgaattt ctccatcctg caagacagca
    37801 atacggtccg ccaacttcaa ggcttcatcc gtatcatggg ttacaaaaat cgttgtcatc
    37861 ccaaactctt tatgcaattc ttttgtcaga acctgcaact gttttctcga aatagcatcc
    37921 aaggccgaaa agggttcatc catgaggaaa atcttgggct gaccaatcat agctcggaca
    37981 ataccgaccc gttgctgttc tccaccagat aattcactag gtaagcgatg cccatactcg
    38041 gctactggta aaccaacctt agccaaaagc tcttctgttt tcttcgtaat ttcttccttg
    38101 ctccacccct tcatttcagg aatgagagca atattttccg caactgttag atttggaaaa
    38161 agagcaatag cctgtaaaac ataaccagta gaaagacgaa gttcacgctc atcatagtct
    38221 ttgatgcgct tcccatccat ataaatattt ccatcagttg gttccaaaag acggttaatc
    38281 atcttgagca tggtcgtctt acctgaccca gaaggcccta ctaaaaccat aaattcccca
    38341 tcctcaatct gtaagttgac atctctcaag acatcctttt ctgtgtagcg cagtgctaca
    38401 tttttgtatt caatcattct ttgtcctcaa tttaaaactt ccctcgattg gtcaagtctt
    38461 ctaccttagg cataacttcc ttattatccc aatgctccac aattttcccg ttctctaaac
    38521 ggaagatatc gtactgggca taagcaacgc catcaatctg agtctgacca tagctaacca
    38581 catagtttcc ttgtcctaag agttggaaaa caaagtcaaa agtgacacta tattcagcca
    38641 catagttttt ataagcagca cttccttgtc caatatcatg attatgctga atcaaatcgt
    38701 ctgccacata atcactccac tgctctagct ccccattttg gaaaatttct gtcaagaaac
    38761 ggcgaaccag ctttttattt tctgctttct tatccaaatc cttgatttca aaatctccaa
    38821 aaatttgatc tagttggtca ttttcaggtg ttcgatagta gtcaatgaca tcccaatgct
    38881 caacaataca accattctca tcctcacgga aagtatccgt cgtcacccat tgagcttctc
    38941 caccattcag atattgatga acatgaacaa agaccagatt gccatcctca atggtgcgga
    39001 caatcttaat ctgacgctct ggatgacgct caaagaaatc tgcaaagaag gctgcaaatc
    39061 cttctttccc gtcaggaaca cctgtcgaat gttggatata ggtatcccct acagactggg
    39121 cttgagcctc agcaactcgt ccgtcttgaa tggcatggat gtataggttg tgagcatttt
    39181 tcacttgttg tgacatattc taaacctcat ttcccttctc tttcagattc gccaaaattc
    39241 tttcttgaaa accttcaaat tggtgaattt cttcctctga aaatcctttg taaaagatag
    39301 tatccaattt ctgactgaca cgatgcccca cttctttctg ggacttgcct aactccgtta
    39361 aaactaaata cttcttacgc ttgtcttttc cacacggact aacaattaca agcttttgtt
    39421 cctctagctt ttttatcata gtcgtcagcg tattattcgc aagtccagtc gcaagcgcga
    39481 tatctgtcgc agttgcgcag ccagtttcac tattccataa aaccgctaaa atcttgccct
    39541 gttcacccct ataaagagcc tcaggatctt gactcagtaa cttttgaaaa atccgcccat
    39601 tcaacaaacg aatatgatgg gctagcaaat gaccatcttt cataacacct ccaatttatt
    39661 tcgatatcga aatgaataaa acaattgtaa cactcatcgt tctaactgtc aactatttcg
    39721 atttagaaat aatttttgat aattatccac accaccatac tccggctcaa ctaactttta
    39781 acgagagttt ctaaactcct tcgtcctcca gtctacaaaa gccttccatt cgtactatcc
    39841 tatattttat gaggggacac atttttccta tcagaccatt tattttaaag atagaagtaa
    39901 atcataattg cttccatctg ttcttttata gtatattgaa gttagactag agcactgtat
    39961 cttctaaaac attgatagaa agcgatttga atttcccaat caatttgttc gtatttatag
    40021 catttcgaaa ctggaatagg acaccatgac tgctaaaaga tttctataaa ttcatttaat
    40081 ttcctcaatc aatttgttca tatcttattt cattccgcta taatttcacc ttaccctatc
    40141 tttttcgtag cacccttcaa acagcctatc ccctaccgtt tgacgattcc tcacttcgct
    40201 ccacttccat tacagaagtt tcttcactac tatgggctcg gctgacttct catgattcct
    40261 tgttactact atttgaacgc tcacgagata gatcttacaa aaaatgcttt gatccacaat
    40321 ggaatcaaag cattttaaag agttcctcat acataagcgc agaagtcgca gttcctctgt
    40381 acttggcttc ttctcttttg acaaagcgag ccaagttgag caactcaggt gctggatgtt
    40441 tgggatttag gagcaattca cgattgacca ggcctgagag acgaactgcc tgcaattgct
    40501 catttgtagt aggcagtttt ttagtagtct ctaggagagc agcaactaaa tcttcactca
    40561 aatcatgtcg agcatgattg taaagatctt ttataaggct ttctaggttt ggttctacca
    40621 tccctaccac ctcccttatg gtttaataat gtttaatcaa atcaaccgtt gaacgatcca
    40681 atttcttcac caaggcttgt aagaaagctt gcgcttctag gaagtcatcc attgcataga
    40741 gggtttggtg agaatggata taacgagcgc agacaccgat agttgttgat gggacaccac
    40801 catttttcag atgagctgca cctgcatctg ttccgccttt accacagtag tattggtact
    40861 tgataccagc ttcttcagcc gttgtcaaaa ggaaatcctt catccctggg agaagcaagt
    40921 gacctggatc atagaaacga atcaaggttc catctccaat cttgccttga ccaccgtaga
    40981 catcacctgc tggtgagcaa tcaactgcga ggaagacttc tgggtcaaac ttggttgtag
    41041 aggtatgagc gccacgcaga ccaacttctt cttggacgtt agaacccaga tagagttcat
    41101 tgccgagttt ttgacccgat aaagcttcag ctagctcgct taccatgagg acaccgtagc
    41161 ggttatccca agcttttgag atgatatttt tttcattggc tgtcaaaatt gcagaactat
    41221 ctggtacaat ggtatcacca ggacggatgc caaaactttc tgcctcagcc ttgtccgcaa
    41281 aaccaccatc aaaaacgata tcggcaatgg ctggcatggt tggtcccccc tttccacgag
    41341 tcaaatgcgg aggaacagaa cctgaaatca caggaatttc atgaccatca cgagtcaaga
    41401 gtttgaaacg ttggctgcta accaccatgg ggttccagcc accgatttct acgacacgga
    41461 aggtaccatc tggcttgatt tcgctgacca taaaaccaac ttcgtccata tgagaagcga
    41521 ccaagacgcg cggtgcatcc acagcttctg aatgtttgat accaaaaata ccacccaagc
    41581 catctgtcac cacttcatcc acatgcggtg tcaacttttc acgaagataa gcacggacag
    41641 gcgcttcatg acctgagact gcagcaagtt ctgttacttc tttaattttt gaaaataatg
    41701 ttgtcatttc agttccttct ttctttcatc cattttacca ctttttatag gagaaggata
    41761 gtgggaaggt ggatttctaa gttagtatct tagtcctgct ctatcttaga aaaggatagt
    41821 attctcttgc atgtagtgca aaatctagta aacattccaa aattaactcg aatatttatt
    41881 tccaaacaaa aaaacaatac accatcaaag ttgtttggat ttttcatgaa atttacagaa
    41941 aatagttgac ttccctttct tctttcttta aatatatagt tggttgagtt tggaatagta
    42001 cgctgtagct gctaaaacat ttctagaaat taatttgact ttcctaatag agttgttcat
    42061 atcttatttc aatttactat agtacaaaac tagaaaagga aaaaatcatg accaaaacaa
    42121 ttcttgttac aggtgggact agctacattg gctcccatac cgttaaagct cttttaaatg
    42181 ctggctatca ggtgcatgtc ctcgataatc tctccacagg aaatcgagcg gctgtggata
    42241 gtcgtgctag ctttaaagaa ctggatgttt atgatgctag cgccttaaag gcttacttag
    42301 aagaaaatca gattgatgct gtcctccatt gtgcaggtga aattgttgtg agcgaaagta
    42361 ttgaaaatcc aagtaaatac ttcactgcca acgttgctgg tatgaaccaa gttctcaaag
    42421 tcttatctga agttggcatt caaaaaatca tgttctcttc gactgcttct ctctatggaa
    42481 ataactgtat tgacaagccg gtgactgaag ataccctgct cgaccctgtc aacccttatg
    42541 cagagacaaa actgatgggc gaacgaatga tttactggat ggccaatcgc tacgactgga
    42601 aatatgttat tttccgttac tttaatgttg ctggggctga aatggatgct tcaaacggtc
    42661 tgcgtgtgaa aaatccaact cacatcattc caaatatcaa caagaccgca ttgggacaaa
    42721 atgatagctt aaaaatattt ggagatgact acgatacacg tgacggttca tgtattcgag
    42781 attacattta tgtcttggac cttgcatagg ctcatgttaa aggaatgaac tacctatttc
    42841 aagaagacag ttcttctcaa atctttaact taggaactaa aaaaggctat actatcaaag
    42901 aaatctttaa aactgctgaa gaattactaa attaaaaaat cccacacgag attgttgctc
    42961 gacgtgctag tgacccagcc agtgtcctag cagatgcttc aaaagctaaa caatatcttg
    43021 attggacggc tagctactcc ctcgaagata ttattttatc agattaaggt aaaaacattt
    43081 tagaatagga taacaaagga gaaagtcttg ttgctctctc cttgttgtat ttattaaatt
    43141 gtcagaaatt ttattgacag attagaaaaa taatgttaca tttatatccg cagatatctt
    43201 tcgataccaa atctacatga aaggacgggg tatgaaactt tctcattatt taattggctt
    43261 acttctactc ctagtctttc tctctattag cattgggacc agtgattttt catggggaaa
    43321 gctatttgat ttcgaccagc agacctggct cctctttcaa gagtcccgtc tcccaagaac
    43381 tatcagtatt ctcctgactg cctctagtat gagtatggca ggccttctca tgcagactat
    43441 tacccaaaat cagtttgctg caccgagtac agttggaacg actgaagccg ccaaactggg
    43501 aatggtgctg agcctttttg tctttccatc ggctagtctg acccacaaga tgctcttcgc
    43561 ttttgtttca tccatcgtat tcaccctctt cttcctagcc tttatgacca tttttactgt
    43621 aaaggaaagg tggatgttgc ctctgattgg gatcatctat agcgggatta tcggctcagt
    43681 cacagaagtt atcgcctatc gtttcaatct ggttcagagt atgactgcct ggacccaggg
    43741 ctccttctcc atgattcaga cccatcagta tgagtggctc ttcttaggcc tcatcatcct
    43801 gataaccgtt tggaaattat cccaaacctt caccatcatg aatctaggga aagaaaccag
    43861 cgagagtttg gggatttcct actccctact tgaaaaactg gccctctttc tggtggcgct
    43921 aacgacaagc gtcaccatga ttaccgtggg tggcctacca tttctcggag ttatcgttcc
    43981 caatcttgtt cgcaagcgct atggagataa tctaagtcaa accaaactca tggtcgcact
    44041 ggttggtgcc aatctagttc tggcttgcga tatcctatcc cgagttctga ttaggcccta
    44101 tgagttgtct gtcagtctct tgctaggaat catcggtagt ctcgtcttta tcctacttct
    44161 ctggagaggg ggacgaaaag atgcagacta aaagcaaaca taccaagctc ttctggattc
    44221 tcattattct tgccatcgga gcttgtcttc tctacttttg gcccatcact cacttgtcag
    44281 cctttgcttg gaagttgcgt tcccaaaaga tcatcgttta tctcttggta gccatcgcga
    44341 ctgggatttc gaccattagt tttcaaaccc tgacggaaaa tcgcttcctg acgcctagta
    44401 ttttgggaat tgaatccttc tacgtcctac tacaaaccct actactggtt tttgaaagca
    44461 agtttcttca acttggcaaa tcccctatct tagaattcct agtcttactt cttgtccagt
    44521 ccctcttctt tctcgcctta caaggttact tgaagacact gatgaagcaa gacctggtct
    44581 tcgtcctgct gatctgtcta gcgctcagaa gtctctttcg aaatatcagc accttccttc
    44641 aagtcctaat ggatccaaac gaatacgata aactgcaaaa tagtcttttt gcctcctttc
    44701 aacatctcaa cacttccatc ctagccatcg gttctctgat catcctcgct ttgacaatct
    44761 ttttctttcg aaaagcagtc gttctagatg tcttgcacct gcaaagagaa acggctcaga
    44821 tattgggact cgatgttgaa aaagaacaga aagagctcct ctggggaatc gtgcttttga
    44881 cctcaacggc cactgccttg gtaggaccta tggccttctt cggctttata ctggccaacc
    44941 tcacctacct gattgtcaaa gactatcagc acaagttact ctttatagtg gccattctgg
    45001 ttggatttat tagcttaacc ttggggcaag ccttgattga acgagtcttt gcactggaaa
    45061 ttcgtatcag tatgatcatt gagagtgtgg gtggcttctt attctttatc ttactatata
    45121 ggaggtctcg tcagtgaaac tggaaaacat tgacaaatcc attcaaaaac aggatatttt
    45181 gcaaggcatt tcgcttgaag tcagtcctca aaaactgaca gcctttattg gtccaaatgg
    45241 tgctggaaaa tcgactctcc tctccatcat gagcaggcta accaagaaag atcagggagt
    45301 tctcagtatc aaaggacgtg aaatcgagag ctggaattcg caagaactgg cccaagaact
    45361 aaccatccta aaacagaaaa tcaattacca agccaaattg actgttgaag aactggtcag
    45421 ttttggacgt tttccctaca gccgaggtcg acttagatca gaagactggg aaaaaatccg
    45481 agaaactctg aactatttag aactgaccaa cttaaaagac cgctacatca atagcctgtc
    45541 aggggggcaa ctccagcgcg tctttatcgc tatggtactg gcccaggata cggactttat
    45601 cttgctggac gaaccactca acaatctcga tatcaagcaa agcgtcagca tgatgcagat
    45661 tcttcgacga ctggtggagg aactcggcaa gaccattatc atcgtcctcc acgatatcaa
    45721 catggccagt cagtatgcag atgaaattgt cgccttcaag gacggccagg tctttagcaa
    45781 gggaagaacc gatcaaatca tgcaggctga cctgctcagt caactttatg agattcccat
    45841 cacgctagct gatatcaatg acaaaaagat ctgtatctat agctagtaac ataaaagctc
    45901 aagttagaga accttcagtc tcttagtcaa taagattaag agactcccta aatcgttatc
    45961 acattttaaa aaggagaaat tatgaaaaca tcccttaaac tttatttcac tgccctagtg
    46021 gccagcttct tgctcctact tggtgcatgt agtacaaact caagcactag tcagacagag
    46081 accagtagct ctgctccaac agaggtaacc attaaaagtt cactggacga ggtcaaactt
    46141 tccaaagttc ctgaaaagat tgtgaccttt gacctcggcg ctgcggatac tattcgcgct
    46201 ttaggatttg aaaaaaatat cgtcggaatg cctacaaaaa ctgttccgac ttatctaaaa
    46261 gacctagtgg gaactgtcaa aaatgttggt tctatgaaag aacctgattt agaagctatc
    46321 gccgcccttg agcctgattt gattatcgct tcgccacgta cacaaaaatt cgtagacaaa
    46381 ttcaaagaaa tcgccccaac cgttctcttc caagcaagca aggacgacta ctggacttct
    46441 accaaggcta atatcgaatc cttagcaagt gccttcggcg aaactggtac acagaaagcc
    46501 aaggaagaat tgaccaagct agacaagagc atccaagaag tcgctactaa aaatgaaagc
    46561 tctgacaaaa aagcccttgc gatcctcctt aatgaaggaa aaatggcagc ctttggtgcc
    46621 aaatctcgtt tctctttctt gtaccaaacc ttgaaattca aaccaactga tacaaaattt
    46681 gaagactcac gccacggaca agaagtcagc tttgaaagtg tcaaagaaat caaccctgac
    46741 atcctctttg tcatcaaccg tacccttgcc atcggtgggg acaactctag caacgacggt
    46801 gtcctagaaa atgcccttat cgctgaaaca cctgctgcta aaaatggtaa gattatccaa
    46861 ctaacaccag acctctggta tctaagcgga ggcggacttg aatcaacaaa actcatgatt
    46921 gaagacatac aaaaagcttt gaaataagcc acttcaaact caatttaata ctcaatgaaa
    46981 atcaaagagc aaactaggaa actagccgca ggttgctcaa aacactgttt tgaggttgca
    47041 gatgaaagct gacgcggttt gaagagattt tcgaagagta taaaattttg acattctaaa
    47101 acgcatccta tcaagttcac tcaaacctga taggatgcgt ttttatcatt ttgaaatcta
    47161 tttaccccac ctcattcccc ttcttgattt cgtttaaggg aaaagcggtc tggaacgggg
    47221 tccttacctg ttttcgacca gggatgacaa cgtaaaatcc gagccaagcc catcaatacc
    47281 cccttaaacc catgtttttc aatagcctga atcatgtagt tggaacaagt cagctcaaag
    47341 cgacaagagg gtggaaagac tggtgagata aaacgttggt aaaagcgcac aggcgctatt
    47401 aaaattcgtt tcattatttc ttagttacag ccatggtgtg tagttggctg atttcttttt
    47461 tattaagacg acgggattct cctggacgga gtcctgtcaa gtctaggtgt ccgaaacgag
    47521 tccgagacaa cttatctact tggagaccaa cagcttcaaa catcttttta acctgatggt
    47581 tacgcccttc atggatggtc aactgcacca cagagcgatt tttgactggg tccactttga
    47641 gaatttcata aacagctggc ttggttttct taccatcaat ctcaagacca cgggtcaagg
    47701 ggcggagatt gtccttattg gccacacctt taacacgcgc gacataaacc ttgtcaatct
    47761 cattacgagg gtgaatcatc tcgtctgtaa agtccccatc attggtcaaa atcaagacac
    47821 ctgatgtatc ccagtccaaa cgacccacag ggtaaatacg ctctttgaca ttgggcaaga
    47881 ggtcgacaac cgtcttgcga cccttatcat ctgtcacact ggaaatcaca ccgcgtggtt
    47941 tgttaagcag atagtagacc ttttcttcgt tgtagatagg ttgaccttca acttcgacct
    48001 tgtcgcctga cttgatagtg gttgctagtt cacgcaccac ttggccgtta accgtcacca
    48061 agccttgctt aatcagctct tctgcttttc tcctactggc cacacctgcg tgggcaatat
    48121 acttattgat tctcatcttc ttctatcctt tcaccaaata attggctttc ttgggcttga
    48181 atctcaagct catcaatcac tggtaattct tctaaatggt ttatccccat gtaatctagg
    48241 aaataatccg tagtcacata gaggttgggg cgccccaata cttccttttt cccgtcttcc
    48301 tttatcaggt caaaagcctg caactttgcc aaggctccac tcgagttaac tccacggatg
    48361 gcatcaattt ctatccgcgt aatcggctgt ttgtaggcaa taatggacaa ggtctcaagg
    48421 gcagcccgag acaagctctg gttgataggc gccttagagt attccttcaa aatctctgca
    48481 aattgaggct tggtcaccaa tctataagca ccacttgtct caatcaaagc caaactggaa
    48541 tctgggtcct tttcatactt ctgggctaat tttcctaaac tttgctggat gcctgtcggt
    48601 ggcagagaga ggagttcagc taactggcgg acccgaatcc catcttcacc cgctacaaac
    48661 aagagcgctt ctatttttgc taaagtactc atctttcctc tctatcaagt ctagctttga
    48721 ggcacttgac tttcttcctt cttttccatg agatagatat ctccaaaact ctcctcttgc
    48781 acgaggatca actcctgggt tttgattaac tctagggttg ccaaaaagag ggtgatgacc
    48841 tcttggacat tctgggcttc cttgaacaaa tcctgcaagc gcaattgatc tcgtccaatc
    48901 aaggactctt tcacgataat catcatgtcc tcaatcttat actcatcccg caagatcgtc
    48961 gtgtgatttt gtgcaaactc ctcttttttc ttggctagga tatttgaaaa agtcaaaaag
    49021 aggtcaatgg tcgtcttgtc atgcacaagc tccgcatctt cgtaaatcaa ctctgtcggc
    49081 gctttggaat aatactgggc ccgttcttgg tgcttggctt ccaagtgctc acccaagagc
    49141 ttgaacttgc gatattcttc gatttgagag aggaggtcct gctccaggtc atcccccaag
    49201 tctgtcactt ctgctacctt cggaaggagt ttacgactct taatcagcat gagctgacta
    49261 gccatgacca tgtactcacc cgtcacttcc agacgcatgg cctgcagggt tgagacatag
    49321 gctagatact gttcgatgac ttccgtaatg ggcacatcgt agatatccat ctggtactta
    49381 gaaaccagat gcaagagcaa gtccaggggt ccttcaaaat cttttaattt aatatccatt
    49441 atctatattt ttctaaggtc aggactgttt ttaatcctaa tttttttgca atttcgtaca
    49501 aatcgacctt gttttctatt tgtcttagaa taaactgttc acgtaagact tgagctgata
    49561 aggatggaaa acctttctcc ttgacaaaag attctaactg acgaaaggcc cactgacgag
    49621 aatagggttt ctctcctctt tcaaaaagat aggtctgccc catcaagggt tccaattctg
    49681 aaagcaaggc cgtgggaatg gtgacaatcc tctgttggga agccttgctg attcgcaaca
    49741 cctgaaaatc cagattgatg tccgcaacct tgatggctaa aatctcactg ggcaagagcc
    49801 ccatttctag gattaagagc gctagcaagc ggccctctgg atggtcgctt tcctgccaaa
    49861 aagagtctag gtatagaatc tctggctttt ccgtcttctt ttcagcttgt ttggctaatt
    49921 ccaagcggta aaagctgtcc acctctcctt tttgatagag aaagtataga aattggttac
    49981 aggccgaaat ctttcgcttc tgggcgctga tttttagatt ggctagctgg gcttggtaaa
    50041 tcttgagact ggtctcagaa atccgctcac ctaccatgtc taaaaattgc tccaaatcat
    50101 acttatagga ctgcttggaa ttgacagaca agccctgctt ttcctctaaa aaggctgaaa
    50161 tcctgtctct cattggcatc gaatctcata ttccttacta aagtcatgca agagggcatt
    50221 aacggccttg aggatggact tgcgcgtaat aatcccttgg aaaataccct ctgcatccac
    50281 aaccggtaag aaggactcat ctactagctt gtgcaagacc tccgtaatgg tgaaatcagg
    50341 cgaaacaacc gctacgtccg tttttgtcat atgaacgata tccgtatccg ccatgatttc
    50401 ttggctcaag tcatgctcca tctgataagc cataatatct ctgagtccaa tcgtcccaac
    50461 aaactgtttt tcatctgtca caacgggaac acgggtatag gtcatctgac tgagcaagag
    50521 ggtcgcatga tccgcattgt gggtatcaat caacacagct agatttttag caggggtcaa
    50581 aaaagtttcc tcctgcccca acaagaaagt ctcaaactcc ttggcaatca tcggctaaac
    50641 tccttggaca aacctggata cacctcgtga tctcgtgtca aaaagtccac tttgaagtaa
    50701 ctatcatcaa tctccacacg agcatagaga cattctctga tggtacctcg tggttgactg
    50761 atagaacctg gatttagaaa gaggatcttg ccttccaacc aagcacttgg cacatgcaag
    50821 tgaccataga ggcagatagc ggcctcttcc tcctgagccc agtagtccaa cttttgaaag
    50881 ttgaaattga tgtcaaacaa gtgaccatga gtttggataa tcttggtcga accaagctca
    50941 gtcaccagac gttctgggta gccggcgtag aagtccatgt tccctttaac aacgcggatg
    51001 ccctcccaaa gtggagaatc cggacgtagt tcagaatcgc cgttatgaaa aacagcatcg
    51061 actttgccca catagcgatc acggacttct tccacaatca agctatcgcc atgggaatcg
    51121 ctcattacaa tgatggtttg ctttgccatg atggaaatac ctccaaaagt ttcttaacgg
    51181 ctaaggcacg gtgagattga ctattttttt cttccagggt taattcagct gatgactcac
    51241 ctgtttctcc tacaaggaag aggggatcat agccaaagcc attttcaccc ttaggttcaa
    51301 agttaatata acctgaccag tctgcttcaa caactaaact ttccttattt gggctggcta
    51361 cgactagggt tgtgtggaac tgagccgagc ggtccttgag ttcaaagacc atggccaatt
    51421 cgtgcaagag tttggcatta ttttcacggt cagttgctcc cacacctgcg aaacgagctg
    51481 accagacgcc tggtaagcca ccaaggacat cgactttgag accagaatca tctgccaaaa
    51541 ccatcttgcc cgttaattga gaaatggttt ctgccttaag gcgggcattt tcttcaaagg
    51601 tcatacctgt ttctgctact tcaggcaggt cagggtagtc attaagattt tccacatcgt
    51661 agcctaactt atcaaagata gctcggaatt ccttggtttt accttcgtta cgagtcgcaa
    51721 tcaacaaggt ttctctgacc ttgcttgtct caaagaaatc atgaacattg accccttctt
    51781 taggcaattc tacatacaag agttgcccat tttcaaccaa gagcagggcc ccatgacgtt
    51841 gaataacttc caagtttcgt cccatttctt gattaagcat gtctaccaca aaggagaaca
    51901 aacggtagat agaaccatag cgtaaaacag taactgaaag cgggaaacca tactcttcat
    51961 ctccaaatat tttggagaat tcaaacagag gaaaatctgt cttatagtcg ctcaaactgt
    52021 taacgccacc aaaaatacta taagacccaa cataccagtc ctggtcatcc ttatattcat
    52081 aaattttatt tgtcataatt ctacatgctc cacatgaatc tctttttcca gccattcttc
    52141 accaatttgt gcaaaacttt ggctactggc tgttgtgtaa aaacggtgat ggagtggtcc
    52201 agcatcgcga ccacgattga tttcaaaata attgagtaag actgagatat cccgtacgca
    52261 ctctgcccca ctatcgatga gctgaacctt tggccccatc acattttgga taatagggcg
    52321 aaggagtgga taatgagtac agcccaaaat caggctatcc acctttccaa ccaagggacg
    52381 cagggtttca tagaccacct tcttggtaac actggttgac agggcacctg actcaaccaa
    52441 gggagcaaac ttgggacagg ccaagctctc cacctgtaag tcgggatcca gatcatggat
    52501 tttctgacgg tatatgtctg attgtaccgt catgggcgtt ccaatcactc cgattttccc
    52561 accttgactg gacttgatgg ctgccgaagc tcctggcaaa attacaccca agacaggaat
    52621 atctagttga gccttgattt cttcccagac gaccgcagtc gcagtgttac aagcaatgac
    52681 aatcattttg acatccttgg tcaagagaaa gttgaccagc tgccaagtat attcacgaat
    52741 ttgctcagca ggacgggggc catagggcgc ccgcgccgaa tctccaatat agacgatttc
    52801 ttcatgggga agctggcgca tgagctcgcg cacaacggtc aagcccccga cacccgaatc
    52861 caaaaaacca attggtcgat tatccataca gtcttctttc tagtcttttt ttctgattga
    52921 tcgttcatta tgattccttg tactgaacga actgaccgac agcttgatag aatgtcaact
    52981 acctctctct taatcataat caaatatcaa tagaatgcaa ggaaaaagtc tcatccctaa
    53041 accataacca acatagtgag aagtctggaa ctttcatccc agacttttcc ttatttattt
    53101 tttcttttta ttgttagcaa gggctgcctt ttgttggcgg atgatttggt ggtaaacttg
    53161 ttgtacctta gcttcgcttg gtttttgacc atttgcactc aaaagagtac gaactgcttc
    53221 agcattcaaa cgtgggttgt cagcaaattc tttttcgatt tgcttacgaa ccaagtacat
    53281 tcctcctaga gctcctccta gaaaagctag cacaatcaat acaattgcta aaagtaaatc
    53341 catcattttt ctcctgtttc tttttgagtc cctttcatta taccacaaac tagccaccct
    53401 gaccagtttg ttctacactt tcagggatgg aatagacagc aaaaagaacc ctgcttttct
    53461 gaaaaagagg tctccttgct aagtttatac tcaatgaaaa tcaaagaaca aactaggaag
    53521 ctagccacag gttgctcaaa gcaccgcttt gaggttgcag ataaaactga cacggtttga
    53581 agagattttc gaagagtatt aatttacata aatagccagt gtttgatagg gtttgagtag
    53641 aattttctca gacacttctg catcttcata gtttgatatc aaaatctgtc cattttggta
    53701 gactgctggc aagtcgattt ccacttcttt agcataaaag ttattgagca ctagtaactt
    53761 ttgatcctca aactggcgtt caaaagcgta gacttgtttg ctatcttcaa aggctggttt
    53821 gtaacttcct tctgaaatga ttggcatttc cttacgcagt cgaatcaagt cttgatagaa
    53881 ggtaaaaatc ggaccctgga tttcattttc tacattgatg tatttatagg atttaccagc
    53941 tttcaaccaa ggagtgcctg ttgaaaatcc tgcattttcc gaagcatccc actgcatggg
    54001 aatgcgtgaa ttatcacgcg acttagcttg aataatctgg aaggcttctt gctgactctt
    54061 tccttcttct aagagcatct gataggcatt aagcgattcg acatccacat aatcagccat
    54121 agaatcatag tctgggtcaa tcatcccgat ttcctcaccc atgtagatat aaggtgtccc
    54181 acgtgacagg tgaatgctgg ctgctagcat ggtggctcct tccttgcgga agttttgaat
    54241 atcgacaaaa cggttcaagg cacgtggttg atcgtgatta ttccaaaaga gggcactcca
    54301 accgtcttta tcactcattt ccttacccca actatggtaa agactcttca actcttcaaa
    54361 atcaaaggga gccaaggtcc acttttgtcc atccttatag tccaccttga ggtgatgaaa
    54421 attaaaggtc atggataatt cctgacgatc aggcgacgaa tagaggacac agttttccat
    54481 ggtggtagaa gacatttccc caactgtcat aaagctatcg tcggatccaa aagtggcttg
    54541 gttcatcata cgcaaatagt tatgaacgat gggtttgtct gtataagctg gcttcccttc
    54601 attttcagga cagtccactg aaacctcgtc cttaccgatc aaattgatca catcaaatcg
    54661 gaaacctttg acacccttgt cgcgccagaa attaacaacc ttgaaaagct ccttacggac
    54721 attggaattg cgccagttaa ggtcagcctg ggtctcatca aataggtgaa gatagtattt
    54781 cccagtatcc ccgaaaggcg tccatgcaga accaccaaac ttagactgcc aatctgttgg
    54841 ttggtcttgg atgaagaaaa agtcttgata atacttatca ccagctaggg ctttctgaaa
    54901 ccattcatgc tctgtcgaac aatgattaag taccatgtcc agcataaagt caatcttgtg
    54961 ctctttaccg acacacacca ttttctcaaa atcagccata tcaccaaaaa gaggatccac
    55021 tgccatataa tctgaaatat cgtaaccatt atcccgttga gggcttggat agaatggatt
    55081 gagccagacc atatccacac ctagtttggc taaataggga attttttcga taatcccacg
    55141 gaaatcccca ataccgtttt cagtggtgtc tttgtaagat tttggataga tttgatagac
    55201 tacttttcct ttatcaagtg tcatctgttt ctccttttct gataaaaggg aggaagcagt
    55261 cttccgtccc tatttgtgct atttcaatta tactcaatga aaatcaaaga acaaactagg
    55321 aagctagcca caggttgctc aaaacactat tttgaggttg cagatagagc tgacgtggtt
    55381 tgaagagatt ttcgaagagt attagattcg tgtagcgacc atgagagatg ctccagcttg
    55441 gatcgttgtc ggataagttc cgggaatagt cgctgt
//
LOCUS       DAVFER010000010        54536 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1105170250
            SAMEA2167659-rid19724873.denovo.010, whole genome shotgun sequence.
ACCESSION   DAVFER010000010 DAVFER010000000
VERSION     DAVFER010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2167659
            Sequence Read Archive: ERR388902
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 54536)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 54536)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928716.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928716.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 04:07:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,118
            CDSs (total)                      :: 2,073
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 120
            CDSs (without protein)            :: 120
            Pseudo Genes (ambiguous residues) :: 0 of 120
            Pseudo Genes (frameshifted)       :: 67 of 120
            Pseudo Genes (incomplete)         :: 47 of 120
            Pseudo Genes (internal stop)      :: 34 of 120
            Pseudo Genes (multiple problems)  :: 23 of 120
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..54536
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2167659-rid19724873.denovo.010"
                     /strain="1105170250"
                     /db_xref="taxon:1313"
     gene            complement(<1..881)
                     /locus_tag="VU534_000599"
     CDS             complement(<1..881)
                     /locus_tag="VU534_000599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000164317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEU1513231.1"
                     /translation="MTKLYGSLEAGGTKFVCAVGDENFNVVEKTQFPTTTPIETIDKT
                     IEFFSKFDNLAGLAVGSFGPIDIDKNSKTYGFITTTPKPNWANVDLLGALRRALNVPM
                     YFTTDVNSSAYGEMVARNNAGGRIENLVYYTIGTGIGAGVIQRGEFIGGVGHPEMGHY
                     YVARHPMDIEKEFKGVCPFHKGCLEGYAAGPSLEARTGVRGETIELNNPVWDVQAYYI
                     AQAAVNATVTFRPDVIVFGGGVMAQQHMLDRVREKFTSLLNGYLPVPDVRDYIVTPAV
                     AGNGSATLGNFVLAKEVS"
     gene            complement(1030..2913)
                     /locus_tag="VU534_000600"
     CDS             complement(1030..2913)
                     /locus_tag="VU534_000600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEU1513232.1"
                     /translation="MNNQEIAKKVIDALGGRENVNSVAHCATRLRVMVKDEEKINKEV
                     IENLEKVQGAFFNSGQYQIIFGTGTVNKMYDEVVVLGLPTSSKDDMKAEVAKQGNWFQ
                     RAIRTFGDVFVPIIPVIVATGLFMGVRGLFNALEMPLPGDFATYTQILTDTAFIILPG
                     LVVWSTFRVFGGNPAVGIVLGMMLVSGSLPNAWAVAQGGEVTAMNFFGFIPVVGLQGS
                     VLPAFIIGVVGAKFEKAVRKVVPDVIDLLVTPFVTLLVMSILGLFVIGPVFHVVENYI
                     LIATKAILSMPFGLGGFLIGGVHQLIVVSGVHHIFNLLEVQLLAADHANPFNAIITAA
                     MTAQGAATVAVGVKTKNPKLKTLAFPAALSAFLGITEPAIFGVNLRFRKPFFLSLIAG
                     AIGGGLASILGLAGTGNGITIIPGTMLYVGNGQLPQYLLMVAVSFALGFALTYMFGYE
                     DEVDATAAAKRAEVAEEKEEVAPAALQNETLVTPIVGDVVALADVNDPVFSSGAMGQG
                     IVVKPSQGVVYAPADAEVSIAFPTGHAFGLKTRNGAEVLIHVGIDTVSMNGDGFETKV
                     AQGNKVKAGDVLGTFDSNKIAAAGLDDTTMVIVTNTGDYASVAPVATGSVAKGDAVIE
                     VKI"
     gene            3289..4743
                     /locus_tag="VU534_000601"
     CDS             3289..4743
                     /locus_tag="VU534_000601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HEU1513233.1"
                     /translation="MEWTTERRYRLYQDWTQEEIQHIKENMAQSPWHTHYHVEPKTGL
                     LNDPNGFSYFDGKWILFYQNFPFGAAHGLKSWAQLESDDLIHFKETGIKVLPDTPLDS
                     HGAYSGSAMQFGDNLFLFYTGNVRDKNWIRHPYQIGALMDKEGKITKIDKILIDQPAD
                     STDHFRDPQIFNFQGQYYAIVGGQDLEKKGFVRLYKAVNNDYTNWQAVGDLDFANDRT
                     AYMMECPNLVFVEEQPVLLYCPQGLDKKVLDYDNIFPNMYKIGASFDPKNAKMVDVSQ
                     LQNMDYGFEAYATQAFNAPDGRALAVSWLGLPDVSYPSDRFDHQGTFSLVKELTIKDD
                     KLYQYPVAAIKDLRASEEAFSNRSQTKNTYELELNLEANSQSEIVLLADKEGKGLSIN
                     FDLVNGQVTVDRSQAGEQYAQEFGTTRSCPIENQATTATIFIDNSVFEIFINKGEKVF
                     SGRVFPHADQNGILIKSGNPTGTYYELDYGRKTN"
     gene            4724..5689
                     /locus_tag="VU534_000602"
     CDS             4724..5689
                     /locus_tag="VU534_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002929307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEU1513234.1"
                     /translation="MVAKLTDVAKLAGVSPTTVSRVINKKGYLSEKTIQKVNEAMREL
                     GYKPNNLARSLQGKSAKLIGLIFPNISNVFYAELIDKLEHQLFKNGYKTIICNSEHDS
                     EKEREYIEMLEANQVDGIISGSHNLGIEDYNRVTAPIISFDRNLSPDIPVVSSDNYAG
                     GVLAAQTLVKTGAQSIIMITGNDNSNSPTGLRHAGFASVLPKAPIINVSSDFSPVRKE
                     MEIKNILTREKPDAIFASDDLTAILVIKIAQELGISVPKELKVIGYDGTYFIENYYPQ
                     LATIKQPLEEIACLTIDLLLQKIEGKEVATTGYFLPVTLLPGKSI"
     gene            complement(5724..6998)
                     /locus_tag="VU534_000603"
     CDS             complement(5724..6998)
                     /locus_tag="VU534_000603"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000704367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HEU1513235.1"
                     /translation="MKISWNGFSKKSYQERLELLKAQALLSPERQASLEKDEQMSVTV
                     ADQLSENVVGTFSLPYSLVPEVLVNGQEYTVPYVTEEPSVVAAASYASKIIKRAGGFT
                     AQVHQRQMIGQVALYQVANPKLAQEKIASKKAELLELANQAYPSIVKRGGGARDLHVE
                     QIKGEPDFLVVYIHVDTQEAMGANMLNTMLEALKPVLEELSQGQSLMGILSNYATDSL
                     VTASCRIAFRYLSRQKDQGREIAEKIALASQFAQADPYRAATHNKGIFNGIDAILIAT
                     GNDWRAIEAGAHAFASRDGRYQGLSCWTLDLEREELVGEMTLPMPVATKGGSIGLNPR
                     VVLSHDLLGNPSARELAQIIVSIGLAQNFAALKALVSTGIQQGHMKLQAKSLALLAGA
                     SESEVAPLVERLISDKTFNLETAQRYLENLRS"
     gene            complement(6998..8170)
                     /locus_tag="VU534_000604"
     CDS             complement(6998..8170)
                     /locus_tag="VU534_000604"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004181031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HEU1513236.1"
                     /translation="MTIGIDKIGFATSQYVLKLQDLAEARGIDPEKLSKGLLLKELSI
                     APLTEDIVTLAASASDSILTEQERQEVDMVIVATESGIDQSKAAAVFVHGLLGIQPFA
                     RSFEIKEACYGATAALHYAKLHVENSPESKVLVIASDIAKYGIETPGEPTQGAGSVAM
                     LITQNPRMMAFNNDNVAQTRDIMDFWRPNYSTTPYVNGVYSTQQYLDSLKTTWLEYQK
                     RYQLTLDDFAAVCFHLPYPKLALKGLKKIMDKSLPQEKKDLLQKHFDQSILYSQKVGN
                     IYTGSLFLGLLSLLENTDSLKAGDKIALYSYGSGAVAEFFSGELVEGYEAYLDKDRLN
                     KLNQRTALSVADYEKVFFEEVNLDETNSAQFAGYENQDFALVEILDHQRRYSKVEK"
     gene            complement(8301..8549)
                     /locus_tag="VU534_000605"
     CDS             complement(8301..8549)
                     /locus_tag="VU534_000605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1513237.1"
                     /translation="MVSSSGSEFQSGWQEHQLIAEKVSKTLDKTFDKDVREIPTSQFY
                     QKFVDEMGRTYSGNLILQELITVNGAYKATYIGELSSN"
     gene            complement(8617..9240)
                     /locus_tag="VU534_000606"
                     /pseudo
     CDS             complement(8617..9240)
                     /locus_tag="VU534_000606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(9302..9751)
                     /locus_tag="VU534_000607"
     CDS             complement(9302..9751)
                     /locus_tag="VU534_000607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HEU1513238.1"
                     /translation="MTLTTFLLQAVASFLAIITFLIVLNVQRSMLLPGGILGMTVWLI
                     YLLLKEPTNVIVATFIAAIIGSCVSQILSILYKTPAVVFILAILAPLVPGYLSYRTTA
                     FFVTGDYNKALASATLVVMLALVISIGMASGTVILRLYHYIKTHRVS"
     gene            complement(9753..10511)
                     /locus_tag="VU534_000608"
     CDS             complement(9753..10511)
                     /locus_tag="VU534_000608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HEU1513239.1"
                     /translation="MEESKELNAVIDVIMLAGTILLKSGSEIHRVEDTMIRIAHSQGI
                     VDCNVLAMPAAIFFSIENTNISRMKRVTSSSYNIEKVCDVNQISRQLVGGQIDLETAF
                     KQLTALQAKPLPYTKLQVTLAATFSAPFFSVMFSGNIYDALGAGVATLFGFAFSLYVE
                     KFIRIPFVTAFAGAFVFGIIAQFWARYTGFPSTADLIIAGAVMPFVPGIALTNAVRDI
                     MTNHINSGMSKMFESLLITLALGAGTSVALVLMN"
     gene            complement(10626..12605)
                     /gene="pknB"
                     /locus_tag="VU534_000609"
     CDS             complement(10626..12605)
                     /gene="pknB"
                     /locus_tag="VU534_000609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="HEU1513240.1"
                     /translation="MIQIGKIFAGRYRIVKQIGRGGMADVYLAKDLILDGEEVAVKVL
                     RTNYQTDPIAVARFQREARAMADLDHPHIVRITDIGEEDGQQYLAMEYVAGLDLKRYI
                     KEHYPLSNEEAVRIMGQILLAMRLAHTRGIVHRDLKPQNILLTPDGTAKVTDFGIAVA
                     FAETSLTQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIIFYEMLTGHIPYDGDSAV
                     TIALQHFQKPLPSVIAENPSVPQALENVIIKATAKKLTNRYRSVSEMYVDLSSSLSYN
                     RRNESKLIFDETSKADTKTLPKVSQSTLTSIPKVQAQTEHKSIKNPSQAVTEETYQPQ
                     APKKHRFKMRYLILLASLVLVAASLIWILSRTPATIAIPDVAGQTVAEAKATLKKANF
                     EIGEEKTEASEKVEEGRIIRTDPGAGTGRKEGTKINLVVSSGKQSFQISNYVGRKSSD
                     VIAELKEKKVPDNLIKIEEEESNESEAGTVLKQSLPEGTTYDLSKATQIVLTVAKKAT
                     TIQLGNYIGRNSTEVISELKQKKVPENLIKIEEEESSESEPGTIMKQSPGAGTTYDVS
                     KPTQIVLTVAKKVTSVAMPSYIGSSLEFTKNNLIQIVGIKEANIEVVEVTTAPAGSAE
                     GMVVEQSPRAGEKVDLNKTRVKISIYKPKTTSATP"
     gene            complement(12602..13342)
                     /locus_tag="VU534_000610"
     CDS             complement(12602..13342)
                     /locus_tag="VU534_000610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HEU1513241.1"
                     /translation="MEISLLTDVGQKRTNNQDYVNHYVNRAGRTMIILADGMGGHRAG
                     NIASEMAVTDLGVAWVDTQIDTVNEVREWFAHYLEIENQKIHQLGQDEAYRGMGTTLE
                     VLAIIDNQAIYAHIGDSRIGLIRGEEYHQLTSDHSLVNELLKAGQLTPEEAEAHPQKN
                     IITQSIGQKDEIQPDFGTVILESGDYLLLNSDGLTNMISGSEIRDIVTSDIPLADKTE
                     TLVRFANNAGGLDNITVALVSMNEEDAE"
     gene            complement(13357..14670)
                     /gene="rsmB"
                     /locus_tag="VU534_000611"
     CDS             complement(13357..14670)
                     /gene="rsmB"
                     /locus_tag="VU534_000611"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HEU1513242.1"
                     /translation="MTKVETARSLALAVLEDVFVNQAYSNIALNKHLKGSQLLAADKG
                     LVTELVYGTVARKLTLEWYLSHFIEDRDQLDSWLYVLLLMSAYQLRYLDKIPDHAVVN
                     EAVELAKLRKKGSEKLVNAVLRRILREGWPDIASIKRKNKRDSIAYSLPVWLVAKLKE
                     EYGEERAKAIFESLLVRNKASIRVTDLSRKEEIQALLEANNSLLATTGLVKEQGHFAG
                     HNLFADGAITIQDESSQLVAPTLDLQGDERVLDACAAPGGKTAHIASYLTTGQVTALD
                     LYDHKLDLIQENAQRLGVEDRVQTQKLDARKVHEFFDQDSFDKILVDAPCSGIGLLRR
                     KPDIKYNKETADFASLQEIQLEILGSVCQILGKGGIITYSTCTIVSEENFQVVKAFLE
                     SHPEFEQVKLEHECKDIMKDGCILITPELYGSDGFFISQFRKISD"
     gene            complement(14663..15598)
                     /locus_tag="VU534_000612"
     CDS             complement(14663..15598)
                     /locus_tag="VU534_000612"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HEU1513243.1"
                     /translation="MTKLIFMGTPDFSATVLKGLLTDDRYEILAVVTQPDRAVGRKKV
                     IQETPVKQAAKEAGLSIYQPEKLSGSPEMEDLMKLGADGIVTAAFGQFLPSKLLDSMD
                     FAVNVHASLLPRHRGGAPIHYALIQGDEEAGVTIMEMVKEMDAGDMISRRSIPITDED
                     NVGTLFEKLALVGRDLLLDTLPAYIAGDIKPEPQDTSQVTFSPNIKPEEEKLDWNKTN
                     RQLFNQIRGMNPWPVAHTFLKGDRFKIYEALPVEGQGNPGEILSIGKKELIVATAEGA
                     LSLKQVQPAGKPKMDIASFLNGVGRTLTVGERFGD"
     gene            complement(15611..18007)
                     /locus_tag="VU534_000613"
     CDS             complement(15611..18007)
                     /locus_tag="VU534_000613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001162119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HEU1513244.1"
                     /translation="MALAKIIVDVPLMQTDQPYSYRIPEEFEGMLEVGMRVHVPFGKG
                     NRLIQGIVLGLKSQSDGEEMEQDLKDIAEVLDFSPVLTPEQLWLAEELRKSVFSYKIS
                     ILKAMLPGFLNSSYDKILYPLEGLSQEERVRLFGSEDSLAFSSLDLAKQAEMMRLTRK
                     GLLGLEYQAVDQKKVKTQSWYEVDHAQLEGVEISTRAKKKLELRDYLLSHPESASLAS
                     LLESYSREQVNFFVDQGAVTIVQKEVQRSAAYFEGIEASRPLELNPEQRQARDAVVSS
                     IGSSQPPFLLQGITGSGKTEVYLQIIQGALDKGKTAILLVPEISLTPQMTERFIARFG
                     DKVAILHSGLSNGEKYDEWRKVERGDAQVVVGARSAIFAPLKNLGVMIIDEEHEAAYK
                     QDSNPRYHAREVAILRAQYNQATLVLGSATPSLESRARAGKGVYQHLRLTQRANPLAT
                     IPEVQVIDFRDYIGQNETSNFTPPLLEAIQDRLVKKEQVVLMLNRRGYSSFVMCRECG
                     TVDTCPNCDISLTLHMDTKTMNCHYCGFSKDIPQVCPNCKSRSIRYYGTGTQKAYDEL
                     AELFPQARILRMDVDTTRKKGSHQALLDQFGRGEADILLGTQMIAKGLDFPNVTLVGV
                     LNADTALNLPDFRSSERTFQLLTQVAGRSGRAEKAGQVLIQSYNPQHYAIRFAKDQDY
                     EGFYAYEMGIRRQLGYPPYYFTIGITLSHKKEEEVFKRAYEVMNILRSGLSETSPILG
                     PTPKPIARTHNLYHYQILIKYRLEDELGSTLNQVLALTQERENSELRLSIDHEPQQFL
                     "
     gene            complement(18073..18387)
                     /locus_tag="VU534_000614"
     CDS             complement(18073..18387)
                     /locus_tag="VU534_000614"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001817694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HEU1513245.1"
                     /translation="MMLKPSIDTLLDKVPSKYSLVILEAKRAHELEAGAPATQGFKSE
                     KSTLRALEEIESGNVTIHPDPEGKREAVRRRIEEEKRRKEEEEKKIKEQIAKEKEDGE
                     KI"
     gene            complement(18412..19038)
                     /gene="gmk"
                     /locus_tag="VU534_000615"
     CDS             complement(18412..19038)
                     /gene="gmk"
                     /locus_tag="VU534_000615"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000775037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HEU1513246.1"
                     /translation="MADRGLLIVFSGPSGVGKGTVRREIFESSENQFQYSVSMTTRAQ
                     RPGEVDGVDYFFRTREEFEELIRQGQMLEYAEYVGNYYGTPLTYVNETLDKGIDVFLE
                     IEVQGALQVKKKVPDAVFIFLTPPDLDELQDRLVGRGTDSAEVIAQRIEKAKEEIALM
                     REYDYAIVNDQVPLAAERVKCVIEAEHFCVDRVIGHYQEMLPKSPTTR"
     gene            complement(19168..20781)
                     /locus_tag="VU534_000616"
     CDS             complement(19168..20781)
                     /locus_tag="VU534_000616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HEU1513247.1"
                     /translation="MEIMSLAIAVFAVIIGLVIGYVSISAKMKSSQEAAELMLLNAEQ
                     EATNLRGQAEREADLLVNEAKRESKSLKKEALLEAKEEARKYREEVDAEFKSERQELK
                     QIESRLTERATSLDRKDDNLTSKEQTLEQKEQSISDRAKNLDAREEQLEEVERQKEAE
                     LERIGALSQAEARDIILAQTEENLTREIASRIREAEQEVKERSDKMAKDILVQAMQRI
                     AGEYVAESTNSTVHLPDDTMKGRIIGREGRNIRTFESLTGVDVIIDDTPEVVTLSGFD
                     PIRREIARMTMEMLLKDGRIHPARIEELVEKNRQEIDNKIREYGEAAAYEIGAPNLHP
                     DLMKIMGRLQFRTSYGQNVLRHSIEVAKLAGIMASELGENAALARRAGFLHDIGKAID
                     HEVEGSHVEIGMELARKYKEPPVVVNTIASHHGDVEAESVIAVIVAAADALSAARPGA
                     RSESLESYIKRLHDLEEIANGFEGVQTSFALQAGREIRIMVNPGKIKDDKVTILAHKV
                     RKKIENNLDYPGNIKVTVIRELRAVDYAK"
     gene            complement(20972..21226)
                     /locus_tag="VU534_000617"
     CDS             complement(20972..21226)
                     /locus_tag="VU534_000617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006152757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HEU1513248.1"
                     /translation="MLLKFTEDAWADYCYWQNQDKKTLKRINKLIKDIQRDPFTGIGK
                     PEPLKYDYQGAWSRRIDAENRLIYMMDGDSVAFLSFKDHY"
     gene            complement(21230..21484)
                     /locus_tag="VU534_000618"
     CDS             complement(21230..21484)
                     /locus_tag="VU534_000618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000388574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HEU1513249.1"
                     /translation="MEAVLYSTFRNHLKDYMKKVNDEFEPLTVVNKNPDEDIVVLSKS
                     EWDSIQETLRIAQNKELSDKVLRGMAQVRAGSTQVHVIEE"
     gene            complement(21722..22819)
                     /locus_tag="VU534_000619"
     CDS             complement(21722..22819)
                     /locus_tag="VU534_000619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000156376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HEU1513250.1"
                     /translation="MTITGIIAEFNPFHNGHKYLLDQAEGLKIVAMSGNFMQRGEPAI
                     VDKWTRTQMALENGADLVVELPFLVSVQAADFFGQGAMDILDRLGIDSLVFGTEEVRD
                     YQKIADLYTEKGAEMEKFVENLPDSLSYPQKTQAMWKEFAGLDFSDNTPNHVLALAYA
                     KAVAGRNIKLHPIQRQGAGYHSVNKDVDFASATALRQHQKDQDFLERFMPSVALFEQA
                     SKVIWEDYFPLLRYQILSNPDLTTIYQVNQEMAVRIKEAIKTAQSVEELVELVTTKRY
                     TKARVRRLLTYILMQARESDLPEAIHVLGFTEKGRQHLKSLKGQVSLVSRIGKEPWDA
                     MTQKADQIYQLGKPSIAEQNFGRVPIRIETN"
     gene            complement(22829..23575)
                     /locus_tag="VU534_000620"
     CDS             complement(22829..23575)
                     /locus_tag="VU534_000620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000605145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEU1513251.1"
                     /translation="MIMATYETFAAVYDAVMDDSLYDKWTNFSLRHLPKTKERKKLLE
                     LACGTGIQSVRFSQAGFDVTGLDLSADMLKIAEKRATSAKQKIAFIEGNMLNLSKAGK
                     YDFVTCYSDSICYMQDEVEVGDVFKDVYNALNEEGVFIFDVHSTYQTDEVFPGYSYHE
                     NAEDFAMLWDTYEDEVPHSIVHELTFFIKEADGSFSRHDEVHEERTYEILTYDILLEQ
                     AGFKSFKLYADFEDKEPTETSTRWFFVAQK"
     gene            complement(23678..24031)
                     /gene="rsfS"
                     /locus_tag="VU534_000621"
     CDS             complement(23678..24031)
                     /gene="rsfS"
                     /locus_tag="VU534_000621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HEU1513252.1"
                     /translation="MNEKELLELVVKAADEKRAEDILALDVQDLTSVTDYLVITSSMN
                     SRQLDAIAANIREKVAQAGFKGSHVEGDAAGGWVLLDLGAVVVHIFSEEMRAHYNLEK
                     LWHEANSVDISEALA"
     gene            complement(24044..24544)
                     /locus_tag="VU534_000622"
     CDS             complement(24044..24544)
                     /locus_tag="VU534_000622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000844697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HEU1513253.1"
                     /translation="MKTAFIIIDVQNVLVETGFQTKSLLEKISYLQNQARSKNIEIIY
                     VQHIENSEAQTSEDWQLSALLNRKPAEKVFQKKYNSIFKETGLKEYLDKQGIEKLVLC
                     GMQTEYCVDTSVKVAFEYGYQLIVPEGAVTTFDGDDIPAETINEFYEDIWEERFADVL
                     DYKHIF"
     gene            complement(24545..25138)
                     /gene="yqeK"
                     /locus_tag="VU534_000623"
     CDS             complement(24545..25138)
                     /gene="yqeK"
                     /locus_tag="VU534_000623"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HEU1513254.1"
                     /translation="MSYQDYINCSREALLEKMAELLPEKRLTHCLGVERAAMELAQRF
                     GVDVEKASLAGLLHDYAKKLSDQEFLVLIDRYQLDPDLKNWGNNVWHGMVGIYKIQED
                     LDLHDSEILRAIEIHTVGAGQMTDLDKVIYVADYIEHNRAFPGVDVAREIASLSLNKA
                     VAYETARTVEYLAHQGFPIYPQTLETYNAFVHYLKED"
     gene            complement(25138..25767)
                     /locus_tag="VU534_000624"
     CDS             complement(25138..25767)
                     /locus_tag="VU534_000624"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HEU1513255.1"
                     /translation="MTIELLTPFTKVELEPEIKEKKRKQVGILGGNFNPVHNAHLIVA
                     DQVRQQLGLDQVLLMPEYQPPHVDKKETIPEHHRLKMLELAIEGIDGLVIETIELERK
                     GISYTYDTMKILTEKNPDTDYYFIIGADMVDYLPKWYRIDELVDMVQFVGVQRPRYKV
                     GTSYPVIWVDVPLMDISSSMVRDFLAQGRKPNFLLPQPVLDYIEKEGLY"
     gene            complement(25819..26130)
                     /gene="yhbY"
                     /locus_tag="VU534_000625"
     CDS             complement(25819..26130)
                     /gene="yhbY"
                     /locus_tag="VU534_000625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HEU1513256.1"
                     /translation="MSLTSKQRAFLNSQAHTLKPIIQIGKNGLNDQIKTSVRQALDAR
                     ELIKVTLLQNTDENIHEVAEILEEEIGVDTVQKIGRILILFKQSSKKENRKISKKVKE
                     I"
     gene            complement(26344..27450)
                     /gene="yqeH"
                     /locus_tag="VU534_000626"
     CDS             complement(26344..27450)
                     /gene="yqeH"
                     /locus_tag="VU534_000626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000391231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="HEU1513257.1"
                     /translation="MEEILCIGCGATIQTTDKAGLGFTPQSALEKGLETGEVYCQRCF
                     RLRHYNEITDVQLTNDDFLKLLHEVGDSDALVVNVIDIFDFNGSVIPGLPRFVSGNDV
                     LLVGNKKDILPKSVKSGKISQWLMKRAHEEGLRPVDVVLTSAQNKHAIKEVIDKIEHY
                     RKGRDVYVVGVTNVGKSTLINAIIQEITGDQNVITTSRFPGTTLDKIEIPLDDGSYIY
                     DTPGIIHRHQMAHYLTAKNLKYVSPKKEIKPKTYQLNPEQTLFLGGLGRFDFIAGEKQ
                     GFTAFFDNELKLHRSKLEGASAFYDKHLGTLLTPPNSKEKEDFPRLVQHVFTIKDKTD
                     LVISGLGWIRVTGIAKVAVWAPEGVAVVTRKAII"
     gene            complement(27453..28043)
                     /locus_tag="VU534_000627"
     CDS             complement(27453..28043)
                     /locus_tag="VU534_000627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HEU1513258.1"
                     /translation="MDCFILVTKENCEKKLRKGARMAIENYIPDFAVEAVYDLTVPSL
                     QAQGIKAVLVDLDNTLIAWNNPDGTPEMKQWLHDLRDAGIGIIVVSNNTKKRVQRAVE
                     KFGIDYVYWALKPFTFGIDRAMKEFHYDKKEVVMVGDQLMTDIRAAHRAGIRSILVKP
                     LVQHDSIKTQINRTRERRVMRKITEKYGPITYKKGI"
     gene            complement(27995..28903)
                     /locus_tag="VU534_000628"
     CDS             complement(27995..28903)
                     /locus_tag="VU534_000628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HEU1513259.1"
                     /translation="MVLEKQLGNGCTWIDLDLGKLNKLEDLSEIYGLDKETIEYALDR
                     NERAHMDYHRESETVTFIYNVLDVKKDKAYYETFPMTFIVEHRRLITISNTKNAYVIE
                     QMTRYLENHDTLSIYKFLFASLEIISNAYYPVIEQMDKSRDEVNDLLRQRTTKKNLFV
                     LSDLETGMVYLTAAAKQNRILLEHIQGHALYRSFDEIEREQFDDAMIEAHQLVSMTDL
                     ISQILQQLSASYNNILNNNLNDNLTTLTIISVLLAVLAVVTGFFGMNVPLPLTDEPHA
                     WLYISLASAGLWIVLSLLLRKIAKKS"
     gene            complement(28960..29520)
                     /locus_tag="VU534_000629"
     CDS             complement(28960..29520)
                     /locus_tag="VU534_000629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel"
                     /protein_id="HEU1513260.1"
                     /translation="MQKFIQAYIEKLDVTTIIENILTKVISLLLLLIVFYIAKKMLHT
                     MVQRIVKPSLKMSRHDVGRQKTISRLLENVFNYTLYFFLLYCILSILGLPVSSLLAGA
                     GIAGVAIGMGAQGFLSDVINGFFILFERQLDVGDEVVLTNGPITVSGKVVSVGIRTTQ
                     LRSEEQALHFVPNRNITVVSNFSRTD"
     gene            29659..30868
                     /gene="sstT"
                     /locus_tag="VU534_000630"
                     /pseudo
     CDS             29659..30868
                     /gene="sstT"
                     /locus_tag="VU534_000630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000713440.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
     gene            30936..31889
                     /locus_tag="VU534_000631"
     CDS             30936..31889
                     /locus_tag="VU534_000631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000028179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HEU1513261.1"
                     /translation="MSISQRTTKLILATCLACLLAYFLNLSSAVSAGIIALLSLSDTR
                     RSTLKLARNRLFSMLLALAIGVLAFHLSGFHIWSLGLYLAFYVPLAYKMGWEIGITPS
                     TVLVSHLLVQESTSPDLLVNEFLLFAIGTGFALLVNLYMPSREEEIQHYHTLVEEKLK
                     DILQRFKYYLSRGDGRNRAQLVAELDTLLKEALRLVYLDHSDHLFHQTDYHIHYFEMR
                     QRQSRILRNMAQQINTCHLAASESLILAQLFSKIAGQLSQTNPASDLLDEIERYLEVF
                     RNRSLPKTREEFETRATLLQLLREAKTFIQVKVDFYQKYRQ"
     gene            complement(32125..32349)
                     /locus_tag="VU534_000632"
     CDS             complement(32125..32349)
                     /locus_tag="VU534_000632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory secretory protein Asp5"
                     /protein_id="HEU1513262.1"
                     /translation="MIEILIVLAIILSLALIVLVTIQPRQNQLFSMDATSNIGKPSYW
                     QSNTLVKVLTLLVSLALFILLLTFMVITYK"
     gene            complement(32354..32533)
                     /gene="asp4"
                     /locus_tag="VU534_000633"
     CDS             complement(32354..32533)
                     /gene="asp4"
                     /locus_tag="VU534_000633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001287962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory secretory system protein Asp4"
                     /protein_id="HEU1513263.1"
                     /translation="MSEEDLFYKDVEGRMEELKQKPIKKEKETRGEKISKTFSLLLGL
                     MILIGLLFTLLGILR"
     gene            complement(32535..33872)
                     /gene="gtfB"
                     /locus_tag="VU534_000634"
     CDS             complement(32535..33872)
                     /gene="gtfB"
                     /locus_tag="VU534_000634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system glycosylation chaperone
                     GtfB"
                     /protein_id="HEU1513264.1"
                     /translation="MIELYDSYSQESRDLHESLGATGLSQLGVVIDADGFLPDGLLSP
                     FTYYLGYEDGKPLYFNQVPVSDFWEILGDNQSACIEDVTQERAVIHYADGMQARLVKQ
                     VDWKDLEGRVRQVDHYNRFGACFATTTYSADSEPIMTVYQDVNGQQVLLENHVTGDIL
                     LTLPGQSMRYFANKVEFITFFLQDLEIDTSQLIFNTLATPFLVSFHHPDKSGSDVLVW
                     QEPLYDAIPGNMQLILESDNVRTKKIIIPNKATYERALELTDEKYHDQFVHLGYHYQF
                     KRDNFLRRDALILTNSDQIEQVEAIAGALPDVTFRIAAVTEMSSKLLDMLCYPNVALY
                     QNASPQKIQELYQLSDIYLDINHSNELLQAVRQAFEHNLLILGFNQTVHNRLYIAPDH
                     LFESSEVAALVETIKLALSDVDQMRQALGKQGQHANYVDLVRYQETMQTVLGG"
     gene            complement(33865..35376)
                     /gene="gtfA"
                     /locus_tag="VU534_000635"
     CDS             complement(33865..35376)
                     /gene="gtfA"
                     /locus_tag="VU534_000635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system glycosyltransferase GtfA"
                     /protein_id="HEU1513265.1"
                     /translation="MTIYNINLGIGWASSGVEYAQAYRAGVFRKLNLSSKFIFTDMIL
                     ADNIQHLTANIGFDDNQVIWLYNHFTDIKIAPTSVTVDDVLAYFGGEESHREKNGKVL
                     RVFFFDQDKFVTCYLVDENKDLVQHAEYVFKGNLIRKDYFSYTRYCSEYFAPKDNVAV
                     LYQRTFYNEDGTPVYDILMNQGKEEVYHFKDKIFYGKQAFVRAFMKSLNLNKSDLVIL
                     DRETGIGQVVFEEAQTAHLAVVVHAEHYSENATNEDYILWNNYYDYQFTNADKVDFFI
                     VSTDRQNEVLQEQFAKYTQHQPKIVTIPVGSIDSLTDSSQGRKPFSLITASRLAKEKH
                     IDWLVKAVIEAHKELPELTFDIYGSGGEDSLLREIIANHQAEDYIQLKGHAELSQIYS
                     QYEVYLTASTSEGFGLTLMEAIGSGLPLIGFDVPYGNQTFIEDGQNGYLIPSSSDHVE
                     DQIKQAYAAKICQLYQENRLEAMRAYSYQIAEGFLTKEILEKWKKTVEEVLHD"
     gene            complement(35388..37760)
                     /gene="secA2"
                     /locus_tag="VU534_000636"
     CDS             complement(35388..37760)
                     /gene="secA2"
                     /locus_tag="VU534_000636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system translocase SecA2"
                     /protein_id="HEU1513266.1"
                     /translation="MFRRLGQDFQLRKVKKILKQINALKGKMSSLSDQELVAKTVEFR
                     QRLSEGESLDDILVEAFAVVREADKRILGMFPYDVQVMGAIVMHYGNVAEMNTGEGKT
                     LTATMPVYLNAFSGEGVMVVTPNEYLSKRDAEEMGQVYRFLGLTIGVPFTEDPKKEMK
                     AEEKKLIYASDIIYTTNSNLGFDYLNDNLASNEEGKFLRPFNYVIIDEIDDILLDSAQ
                     TPLIIAGSPRVQSNYYAIIDTLVTTLVEGEDYIFKEEKEEVWLTTKGAKSAENFLGID
                     NLYKEEHASFARHLVYAIRAHKLFTKDKDYIIRGNEMVLVDKGTGRLMEMTKLQGGLH
                     QAIEAKEHVKLSPETRAMASITYQSLFKMFNKISGMTGTGKVAEKEFIETYNMSVVRI
                     PTNRPRQRIDYPDNLYITLPEKVYASLEYIKQYHAKGNPLLVFVGSVEMSQLYSSLLF
                     REGIAHNVLNANNAAREAQIISESGQMGAVTVATSMAGRGTDIKLGKGVAELGGLIVI
                     GTERMESQRIDLQIRGRSGRQGDPGMSKFFVSLEDDVIKKFGPSWVHKKYKDYQVQDM
                     TQPEVLKGRKYRKLVEKAQHASDSAGRSARRQTLEYAESMNIQRDIVYKERNRLIDGS
                     RDLEDVVVDIIERYTEEVAADHYASRELLFHFIVTNISFHVKEVPDYIDVTDKTAVRS
                     FMKQVIDKELSEKKELLNQHDLYEQFLRLSLLKAIDDNWVEQVDYLQQLSMAIGGQSA
                     SQKNPIVEYYQEAYAGFEAMKEQIHADMVRNLLMGLVEVTPKGEIVTHFP"
     gene            complement(37753..38193)
                     /gene="asp3"
                     /locus_tag="VU534_000637"
     CDS             complement(37753..38193)
                     /gene="asp3"
                     /locus_tag="VU534_000637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system protein Asp3"
                     /protein_id="HEU1513267.1"
                     /translation="MIITQRQSIHWGEVGGTYMYGTTVSYYPDKSVRLYNPLLPSGEI
                     LKTWFSSVNYQAARTQPQLPLLKRKQEYQLSLVFDCQPENGVYTKITFFDRYGDILEK
                     KVEKVKDFIFTYPEDSYTYRVSLLSAGFESLTFYHFSIKEIRSV"
     gene            complement(38190..39725)
                     /gene="asp2"
                     /locus_tag="VU534_000638"
     CDS             complement(38190..39725)
                     /gene="asp2"
                     /locus_tag="VU534_000638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system protein Asp2"
                     /protein_id="HEU1513268.1"
                     /translation="MSKELNILQIGLANWENHYDIPENMSWYYFYPNSSKALREIIEK
                     EDINRFHAVLIEDGQYSRDLFSYVKYFEPYTLFYNQNLQINDREVVDFLKKRCAQAID
                     FLSPQQLINDLSKSLFGGGYGDKLFPPTIQVNPNFTGAISYQGLDYVSLEGEFGQDFA
                     QLAYWAYNIMVQKTLPIELWLEYEKEGNCDFRLVIRKMWSGSVDDFFEEVIVSEKDLE
                     QALFMDSRDGDYFLSISVEARGRGTIKLGNLHQRWSRKQFGKFVLGGNILHDSKRDEI
                     NYFFHPGDFKPPLTVYFAGYRPAEGFEGYFMMKTLGCPFILFSDPRLEGGAFYLGTDE
                     LEGKVKDTITHYLDYLGFDHKDLILSGLSMGTFPALYYGASFEPHAIIVGKPLANLGT
                     IASRGRLDAPGVSNLAFDCLIHHTGGTSSQDMTELDQRFWKIFKQANFSKTTFGLSYM
                     KDEEMDPQAYEQLVSYLCNTGAKILSKGTAGRHNDDTDTNISWFLHFYRMVLETGFGR
                     EKR"
     gene            complement(39709..41289)
                     /gene="asp1"
                     /locus_tag="VU534_000639"
     CDS             complement(39709..41289)
                     /gene="asp1"
                     /locus_tag="VU534_000639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000291149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system protein Asp1"
                     /protein_id="HEU1513269.1"
                     /translation="MYYFIPAWYGSERTWHADITPWYFSHFRLEFDDTFHQIRLFQEQ
                     DIDSRLLVLAYQPHLRYFLYRHGVLEMDTYSVFDVMQDFHNLHTQVLSIRDIEWDDDC
                     EFIYSPFTIIVQKNGKKFAKVEHGVEGFISDIQYFEPNGQIHMHHIVDDRGFVSSIIF
                     FEDGQAAYQEYLNLKGEWQFRERLKEGGQVEVNPILGYRFKMLTYQNMGDLVAEFFEN
                     YLQTYVKDQDIFMLPSHSHHDQLVLDRLPSTNPKLLSLFIGRNPQDTFRDLDVTFEKS
                     DLILVDREDSLRLLQELYPERMHQCYHLSSFDTRLRLGRSQTKKESIIYFQLDFEQGI
                     DNQALLQVLSFVAENKDTEVIFGAFAASQEQMNEVEGIVESFIQENIQSENLGKAIDY
                     GDAENPLEENQHQDLRLQFVNLNDELDLIKTLEFVRLIVDLNRHPHLYTQIAGISAGI
                     PQINLVETVYVEHLKNGYLLADVTEFSKAAHYYTDRLKEWNESLIYSIDKIKEHTGQQ
                     FLGKLEKWIEEVKNVKGT"
     gene            complement(41299..42516)
                     /gene="secY2"
                     /locus_tag="VU534_000640"
     CDS             complement(41299..42516)
                     /gene="secY2"
                     /locus_tag="VU534_000640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000161857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system protein translocase subunit
                     SecY2"
                     /protein_id="HEU1513270.1"
                     /translation="MTKIYSSIAVKKGLFTSFLLFIYVLGSRIILPFVDLNTKDFLGG
                     STAYLAFSAALTGGNLRSLSIFSVGLSPWMSAMILWQMFSFSKRLGLTSTSIEIQDRR
                     KMYLTLLIAVIQSLAVSLRLPVQSSYSAILVVLMNTILLIAGTFFLVWLSDLNASMGI
                     GGSIVILLSSMVLNIPQDVLETFQTVHIPTGIIVLLALLTLVFSYLLALMYRARYLVP
                     VNKIGLHNRFKRYSYLEIMLNPAGGMPYMYVMSFLSVPAYLFILLGFIFPNHSGLAAL
                     SKEFMVGKPLWVYVYISVLFLFSIIFAFVTMNGEEIADRMKKSGEYIYGIYPGADTSR
                     FINRLVLRFSVIGGLFNVIMAGGPMLFVLFDEKLLRLAMIPGLFMMFGGMIFTIRDEV
                     KALRLNETYRPLI"
     gene            complement(42573..43478)
                     /locus_tag="VU534_000641"
     CDS             complement(42573..43478)
                     /locus_tag="VU534_000641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001292324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEU1513271.1"
                     /translation="MSELISVVVPIYNTGKYLVECVEHILKQTYQNIEIILVDDGSTD
                     NSGEICDAFMMQDNRVRVLHQENKGGAAQAKNMGISVAKGEYITIVDSDDIVKENMIE
                     TLYQQVQEKDADVVIGNYYNYDESDGNFYFYVTGQDFCVEELAIQEIMNRQAGDWKFN
                     SSAFILPTFKLIKKELFNEVHFSNGRRFDDEATMHRFYLLASKIVFINDNLYLYRRRS
                     GSIMRTEFDLSWARDIVEVFSKKISDCVLAGLDVSVLRIRFVNLLKDYKQTLEYHQLT
                     DTEEYKDICFRLKLFFDAEQRNGKS"
     gene            complement(43478..44674)
                     /locus_tag="VU534_000642"
     CDS             complement(43478..44674)
                     /locus_tag="VU534_000642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001232144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HEU1513272.1"
                     /translation="MRKSIVLAADNAYLIPLETTIKSVLYHNRDVDFYILNSDIAPEW
                     FKLLGRKMEVVNSTIRSVHIDKELFESYKTGPHINYASYFRFFATEVVESDRVLYLDS
                     DIIVTGELATLFEIDLKGYSIGAVDDVYAYEGRKSGFNTGMLLMDVAKWKEHSIVNSL
                     LELAAEQNQVVHLGDQSILNIYFEDNWLALDKTYNYMVGIDIYHLAQECERLDDNPPT
                     IVHYASHDKPWNTYSISRLRELWWVYRDLDWSEIAFQRSDLNYFERSNQSKKQVMLVT
                     WSADIKHLEYLVQRLPDWHFHLAAPCDCSEELTSLSQYTNVTVYQNVLHSRIDWLLDD
                     SIVYLDINTGGEVFNVVTRAQESGKKIFAFDITRKSMDDGLYDGIFSVERPDDLVDRM
                     KNIEIE"
     gene            complement(44683..45903)
                     /locus_tag="VU534_000643"
     CDS             complement(44683..45903)
                     /locus_tag="VU534_000643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000938701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase family 8"
                     /protein_id="HEU1513273.1"
                     /translation="MRNTKRAVVFAGDYAYIRQIETAMKSLCRHNSHLKIYLLNQDIP
                     QEWFSQIRIYLQEMGGDLIDCKLIGSQFQMNWSNKLPHINHMTFARYFIPDFVTEDKV
                     LYLDSDLIVTGDLTDLFELDLGENYLAAARSCFGAGVGFNAGVLLINNKKWGSETIRQ
                     KLIDLTEKEHENVEEGDQSILNMLFKDQYSSLEDQYNFQIGYDYGAATFKHQFIFDIP
                     LEPLPLILHYISQDKPWNQFSVGRLREVWWEYSLMDWSVILNEWFSKSVKYPSKSQIF
                     KLQCVNLTNSWCVEKIDYLAEQLPEVHFHIVAYTNMANELLALTRFPNVTVYPNSLPM
                     LLEQIVIASDLYLDLNHDRKLEDAYEFVLKYKKPMIAFDNTCSENLSEISYEGIYPSS
                     IPKKMVAAIRSYMR"
     gene            complement(45934..48378)
                     /locus_tag="VU534_000644"
     CDS             complement(45934..48378)
                     /locus_tag="VU534_000644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_1767 family glycosyltransferase"
                     /protein_id="HEU1513274.1"
                     /translation="MNKTIVLAGDRNYTRQLETTIKSILYHNRDVKIYILNQDIMPDW
                     FRKPRKIARMLGSEIIDVKLPEQTVFQDWEKQDHISSITYARYFIADYIQEDKVLYLD
                     SDLIVNTSLEKLFSICLEEKSLAAVKDTDGITFNAGVLLINNKKWRQEKLKERLIEQS
                     IVTMKEVEEGRFEHFNGDQTIFNQVLQDDWLELGRAYNLQVGHDIVALYNNWQEHLAF
                     NDKPVVIHFTTYRKPWTTLTANRYRDLWWEFHDLEWSQILQHHMGEFELISPLDKEFS
                     CLTLTNSQDLEGIEELVTALPEVVFHIAAWTDMGDKLKKLAVYNNVRLHPQIVPPVLD
                     KLKKSTNLYLDINHGSADENFLKSLQEQEKTLLAFQSTQHGELGQIVFENGKVSFMID
                     TIKDFKKNGHLTCFRQLPSLTCLTFTASQYIEQLDYLAGQLPNVVFQIAAWTAMGPKL
                     YDLSNRYPNIQLYPAISRDKLDELKEKMDAYLDINLLTSTSDIVAEMAHLSKPILAFY
                     KSQNGNNGQRLYSSEHPERMLADLQKLITKDMLEKPLDIIQVKGIDETLDYIIEHNSS
                     LVRFGDGEINMLAGHSIPYQDYDEELVSIMRDIIGQESREDLVVCLPDAFTDRFRFTS
                     WAIPFWKDHMDHYMDFYRELCSDSWYGSTFVSRPYIDFEDKSQAKAQFEKLKSIWENR
                     DLLIVEGATSRSGVGNDLFDEANSIKRIICPSHSAFSRVHELEQEIEKYAGGRLILCM
                     LGPTAKVLSYNLCQMGYQVLDVGHIDSEYEWMKMGAKTKVKFSHKHTAEHNFDQDIEF
                     IDDETYNSQIVARILN"
     gene            complement(48388..49398)
                     /locus_tag="VU534_000645"
     CDS             complement(48388..49398)
                     /locus_tag="VU534_000645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000766254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HEU1513275.1"
                     /translation="MKLHLTNLYGMAGDSTVILAQNAVQKIASQLGFREVGIYFYNIA
                     SDSPSEMNKRLDGIMASISIGDILVFQSPTWNGFEFDRLLFDKLKDMQVKIICFIHDV
                     VPLMFDSNYYLMKDYLYMYNLSDVLIVPSERMKTRLMEEGLTTKKILVQGMWDHPHDL
                     SLYTPAFKKELFFAGSLERFPDLQNWSQDTPLRVFSNKGEASSSARSLSIEGWKKDEE
                     LLLELSKGGFGLVWGTHQNEGESNQYYTLNISHKVSTYLTAGIPVIVPSSLSTAKFIV
                     DQGLGFMADSLEEVHEIVDKMNLQEYQEMTNRIKTFSYLLKEGYFTKKLLVDAIYHLG
                     ID"
     gene            complement(49427..50302)
                     /locus_tag="VU534_000646"
     CDS             complement(49427..50302)
                     /locus_tag="VU534_000646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000426741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEU1513276.1"
                     /translation="MADELISIVVPIYNVENYLRMCLDSIQNQTYQNFECLLINDGSP
                     DHSSKICEEFVEKDSRFKYFEKANGGLSSARNLGIECSGGAYITFVDSDDWLEHDALD
                     RLYGALKKENADISIGRYNSYDETRYVYMTYVTDPDDSLEVIEGKAIMDREGVEEVRN
                     GNWTVAVLKLFKRELLQDLPFPIGKIAEDTYWTWKVLLRASRIVYLNRCVYWYRVGLS
                     DTLSNTWSEKRMYDEIGAREEKIAILASSDYDLTNHILIYKNRLQRVIAKLEEQNMQF
                     TEIYRRMMEKLSLLP"
     gene            complement(50307..51521)
                     /locus_tag="VU534_000647"
     CDS             complement(50307..51521)
                     /locus_tag="VU534_000647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HEU1513277.1"
                     /translation="MNTKSIVFNADNDYVDKLETAIKSICCYNNCLKFYVFNDDIASE
                     WFLMMNKRLKTIQSEIVNVKIVDHVLKKFHLPLKNLSYATFFRYFIPNFVKESRALYL
                     DSDIIVTGSLDYLFDIELDGYALAAVEDSFGDVPSTNFNSGMLLVNVDTWRDEDACSK
                     LLELTNQYHETAYGDQGILNMLFHDRWKRLDRNFNFMVGMDSVAHIEGNHKWYEISEL
                     KNGDLPSVIHYTGVKPWEIISNNRFREVWWFYNLLEWSDLLLRKDIISRSFEELVYSP
                     KAHTAIFTASCEMEHVEYLIENLPEVHFSILAHTYFASSVVALLRYSNVTIYPCFSPF
                     DYRKILDNLDFYLDINHYKEVDNIVSVVQQLSKPIFTFENTSHDIGNQTNIFSSTEPN
                     KMVEAIRQFIGE"
     gene            complement(51828..53912)
                     /locus_tag="VU534_000648"
     CDS             complement(51828..53912)
                     /locus_tag="VU534_000648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000341103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HEU1513278.1"
                     /translation="MDDKITVIVPVYNVENYLRKCLDSIITQTYKNIEIVVVNDGSTD
                     ASGEICKEFSEMDHRILYIEQENAGLSAARNTGLNNMSGNYVTFVDSDDWIEQDYVET
                     LYKKIVEYQADIAVGNYYSFNESEGMFYFHILGDSYYEKVYDNVSIFENLYETQEMKS
                     FALISAWGKLYKARLFEQLRFDIGKLGEDGYLNQKVYLLSEKVIYLNKSLYAYRIRKG
                     SLSRVWTEKWMHALVDAMSERITLLANMGYPLEKHLAVYRQMLEVSLANGQASGLSDT
                     ATYKEFEMKQRLLNQLSRQEESEKKAIVLAANYGYVDQVLTTIKSICYHNRSIRFYLI
                     HSDFPNEWIKQLNKRLEKFDSEIINCRVTSEQISCYKSDISYTVFLRYFIADFVQEDK
                     ALYLDCDLVVTKNLDDLFATDLQDYPLAAVRDFGGRAYFGQEIFNAGVLLVNNAFWKK
                     ENMTQKLIDVTNEWHDKVDQADQSILNMLFEHKWLELDFDYNHIVIHKQFADYQLPEG
                     QDYPAIIHYLSHRKPWKDLAAQTYREVWWYYHGLEWTELGQNHHLHPLQRSHIYPIKE
                     PFTCLIYTASDHIEQIETLVQSLPDIQFKIAARVIVSDRLAQMTIYPNVTIFNGIHYL
                     VDVDNELVETSQVLLDINHGEKTEEILDQFANLGKPILSFENTKTYEVGQEAYAVDQV
                     QAMIEKLREISK"
     gene            complement(53973..>54536)
                     /locus_tag="VU534_000649"
     CDS             complement(53973..>54536)
                     /locus_tag="VU534_000649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEU1513279.1"
                     /translation="SASASTSASASASTSASASASTSASESASTSASASASTSASESA
                     STSASASASTSASASASTSASASASTSASASASTSASASASTSASASASTSASASTSA
                     SASASTSASASASTSASASASTSVSNSANHSNSQVGNTSGSTGKSQKELPNTGTESSI
                     GSVLLGVLAAVTGIGLVAKRRKRDEEE"
BASE COUNT        16024 a        12225 c         9790 g        16497 t
ORIGIN      
        1 gaaacttctt ttgcaagaac aaagttccca agtgtggcag aaccatttcc tgcgactgct
       61 ggcgtcacga tatagtcacg cacatctggt actggtaggt aaccattaag aagagatgta
      121 aatttctcac ggacacggtc cagcatatgt tgttgagcca tgacccctcc accaaagaca
      181 atcacgtctg ggcggaaagt cactgtcgca ttaaccgcag cttgagcgat atagtaggct
      241 tgaacatccc aaacagggtt gttgagttca atagtttccc cacgtacacc tgtacgagct
      301 tccaaacttg gaccagctgc ataaccttct agacatccct tatggaaagg acaaacaccc
      361 ttaaactctt tttcaatatc cattgggtgt ctagcaacat aataatgacc catttcaggg
      421 tgacccacac caccgataaa ctcaccacgt tggatgacgc ctgcaccgat acctgtaccg
      481 attgtgtagt aaaccaagtt ttcgatacga ccaccagcat tgttacgggc aaccatttca
      541 ccgtaagcag agctgtttac gtctgttgtg aagtacattg gcacgtttag ggcgcgacga
      601 agggcaccaa gcaagtctac atttgcccag tttggttttg gagtcgtcgt gataaagcca
      661 taagtttttg agtttttgtc aatatcaatc ggcccaaatg aaccaactgc aagaccagca
      721 aggttatcga attttgagaa gaactcaatg gttttatcga ttgtttcgat tggagttgtt
      781 gttggaaatt gtgttttttc tacaacgtta aagttttcat caccgacagc acagacaaac
      841 tttgtaccgc ccgcttccaa gcttccatat aattttgtca tgataaacct cttgttttta
      901 ttttctttat tatagcatac ttcgaaagtc taaatgtctc tattttttag attttcctct
      961 gtaaatctta ctatctaata aaaacgaaca aacatgtcat ttgttcgttt tcacattaga
     1021 gaggattgat tagattttca cttcgatcac agcatccccc ttagcaactg aacctgttgc
     1081 gactggagct actgaagcgt agtcacctgt atttgtaacg ataaccattg ttgtatcatc
     1141 aagtccagct gcagcgattt tgtttgagtc aaatgttcca agaacatcgc cagctttcac
     1201 cttattacct tgagcaactt ttgtttcaaa accgtcaccg ttcatagata cagtatcaat
     1261 accaacatga atcaaaactt cagcaccatt tcttgttttc aaaccaaaag cgtgccctgt
     1321 tggaaaggca attgaaactt cagcatcagc tggtgcatag accacgcctt ggcttggttt
     1381 cacaacgata ccttgtccca tagctccact tgagaagact gggtcattga catcagcaag
     1441 agcgacaaca tcaccgacga taggagttac aagtgtttca ttttgaagag ctgctggcgc
     1501 aacttcttct ttttcttcag ccacttcagc tcgttttgca gctgcagttg cgtctacttc
     1561 atcttcgtaa ccaaacatgt aagtaagagc aaaaccaagg gcaaatgata cagctaccat
     1621 aagaaggtat tgtggaagtt gtccgttacc aacataaagc attgtaccag ggatgatggt
     1681 gataccatta ccagtaccag caagtccaag gatagaagcc aatccaccac cgattgcacc
     1741 agcaatcaat gaaaggaaga atggtttacg gaagcgcaag ttcaccccga agatagcagg
     1801 ctctgtaata cctaggaagg cagaaagagc agccgggaaa gcaagtgttt tcagttttgg
     1861 attttttgtt ttaacaccaa ccgcaacagt agcagcacct tgagctgtca tagcagctgt
     1921 gatgatagcg ttgaatgggt tagcatggtc agcagcaagt aattgcactt caagcaagtt
     1981 gaagatgtgg tgcacacctg acacgacgat caattggtga accccaccaa tcaagaaacc
     2041 accaagacca aatggcatgc taagaatcgc ttttgtagca ataaggatgt agttttcaac
     2101 aacgtggaaa actggtccaa tgacaaagag tccaaggata gacatgacca aaagtgtcac
     2161 gaatggtgtt accaagaggt caatgacatc tggaacaacc ttgcggacag ctttttcaaa
     2221 tttagctccg acaaccccga tgatgaaggc tggaagaacg gaaccttgca aaccaacaac
     2281 agggatgaaa ccaaagaagt tcatcgctgt tacttcacca ccttgagcaa ctgcccaagc
     2341 gtttggaagt gagccagaga caagcatcat accaagaacg ataccaacgg caggatttcc
     2401 accaaataca cggaaggttg accacacaac caaacctggc aagatgatga aggctgtatc
     2461 tgtcaagatt tgtgtgtaag ttgcaaagtc acctggaagt ggcatttcaa gagcgttgaa
     2521 aagaccacgc acacccatga agagacctgt cgctacgata actgggatga ttggaacgaa
     2581 aacatcacca aaagtacgga tagcacgttg gaaccagttc ccttgtttag caacttctgc
     2641 tttcatgtca tccttagatg atgttggtaa tccaagtaca acaacttcat cgtacatttt
     2701 gttaactgta cctgtaccaa agataatttg gtattgccct gagttaaaga aagcaccttg
     2761 aactttttcc aagttctcaa tcacttcttt attgattttc tcttcatctt tgaccatgac
     2821 acgtagacga gtcgcacagt gggcaacact attgacattt tcacgtccgc ccaaggcatc
     2881 gatgactttt tttgcaattt cctgattgtt catttgcaaa aatctcctta tataacattt
     2941 tgttcttgtt tgaaagcgat tttattcgcc cttacgacta ttattttatc atgttttaaa
     3001 aatatgtcaa gcgttttgca gaaaaaaatt ctatccactt agtgggcaag ctttagattg
     3061 attgtttttg actgtttcat caggaattcc ttgaaaaata agtttgaaac cttggttaaa
     3121 aagtatttta tttcattatc tttcacattt tcgtaaaaat ttgattgatt tcctgtattt
     3181 attttatgat aatcctttga cagtttttcc tcttttttaa cataaaaggc ttgcattttt
     3241 tatcgaaaac agttactatt aaaagtgata agatttttgg aggaatgaat ggaatggaca
     3301 actgagcgtc gttacagact ttatcaagat tggacgcaag aagaaattca acatataaag
     3361 gaaaatatgg cacaatctcc atggcatact cattaccatg ttgagccaaa aacaggactt
     3421 ctcaacgacc caaatggctt ttcttacttt gatggcaagt ggatcctctt ttaccagaat
     3481 tttccttttg gtgcagccca cggtttaaaa tcttgggcac agctagaaag tgatgatttg
     3541 attcacttta aagaaactgg aatcaaagtt ttaccagata ctccattaga tagccacggt
     3601 gcctactctg gttctgccat gcaatttggc gataacttat tcctatttta tacaggaaat
     3661 gttcgcgata aaaactggat ccgtcaccca taccagatcg gtgctttgat ggacaaggag
     3721 ggtaagatta caaagattga caagatcttg attgaccagc cagcagactc tactgaccac
     3781 ttccgcgatc cacaaatttt taactttcag ggtcaatatt atgccattgt cggcggacaa
     3841 gacttggaga aaaaaggttt cgttcgtctc tacaaggctg tcaataacga ctacacaaac
     3901 tggcaagcag ttggcgacct tgactttgct aacgaccgta ctgcctacat gatggaatgt
     3961 cctaatttgg tctttgtaga ggaacaacct gtccttctct actgtccaca aggattggat
     4021 aagaaagttc tagactacga taatatcttt ccaaatatgt ataagatcgg ggcttccttt
     4081 gaccctaaaa atgccaaaat ggtagatgtg tctcaacttc aaaacatgga ttacggtttc
     4141 gaagcctatg caactcaagc cttcaacgct cctgatgggc gtgctctagc agttagctgg
     4201 cttggtttgc cagatgtttc ttacccatct gaccgttttg accaccaagg aaccttctct
     4261 ttggtcaagg aactcactat caaagacgac aagctctacc agtatccagt cgctgctatt
     4321 aaggaccttc gtgcttctga agaagccttc tcaaaccgtt cccaaaccaa gaacacttac
     4381 gaacttgaac tcaacttgga agctaatagc cagagcgaga ttgtcttact tgctgataaa
     4441 gaaggtaagg gactttcaat caactttgac cttgtaaacg gtcaagtaac agtggatcgt
     4501 agccaggctg gagaacagta tgcccaagaa tttgggacaa ctcgttcttg ccctatcgag
     4561 aatcaggcta ctactgctac aatcttcatc gataactctg tctttgaaat tttcatcaat
     4621 aaaggagaaa aagtattttc tggtcgtgtc ttcccacatg cggaccaaaa tggtatcctg
     4681 attaaatctg gaaacccaac tggaacttac tatgaattag attatggtcg caaaactaac
     4741 tgatgtcgcc aaacttgcag gcgtcagtcc tactaccgtt tctcgggtta tcaataaaaa
     4801 agggtatcta tctgagaaaa ccatccaaaa agtcaatgaa gccatgcgag aattgggcta
     4861 taaacccaac aacctggctc gtagtctgca aggaaaatca gctaagttaa tcggcttgat
     4921 tttccccaat atttccaatg ttttctatgc agaattgatt gataaattgg aacaccaact
     4981 cttcaaaaat ggttacaaga ccatcatctg caacagtgaa catgattctg agaaggaacg
     5041 cgaatacatc gaaatgttgg aagccaatca ggtggacggc atcatttctg gtagtcacaa
     5101 cctaggaatc gaagactaca atcgtgtgac agcgccgatt atttcctttg accgaaacct
     5161 atcgccagac atccctgtcg tctcctctga caactatgct ggtggggttc ttgctgccca
     5221 aaccttggtc aagacaggtg cccagtctat catcatgatt acagggaatg acaattctaa
     5281 ttcgccaacc ggactgcgcc acgctggttt tgcatccgta ctcccaaaag ctcctattat
     5341 caatgtttcc agtgactttt ctcccgtcag aaaagaaatg gaaatcaaga atatcttgac
     5401 ccgggaaaaa ccagatgcca tttttgcttc ggatgatttg acagctattc tggtcattaa
     5461 aatcgctcaa gaattgggca tttctgtccc aaaagagctc aaggtcatcg gctatgatgg
     5521 gacctacttt atcgaaaatt actaccctca attggctact atcaagcaac ctttggaaga
     5581 gattgcttgt ctcactattg atcttctctt gcaaaagatt gaaggcaagg aagtcgccac
     5641 aactggttac ttcttaccag ttacgctatt accaggaaaa agtatttaaa cacaagaaaa
     5701 ctcagaccga ttcgtctgag tttttatgat cttaaatttt cgagatagcg ctgggctgtc
     5761 tctaggttaa aggttttatc tgagatgagg cgctctacta ggggagcaac ttcagattca
     5821 ctagccccag ctaggagagc tagggatttg gcctgtagtt tcatgtggcc ttgctggatg
     5881 cccgtactta ccaaggcttt gagggctgca aaattttgag caagaccgat ggacacgata
     5941 atctgggcta attctctggc agaaggattt cctagtagat catgactgag aactacacgt
     6001 gggttgaggc cgatagagcc acccttagtc gctacaggca tgggcagggt catctcaccg
     6061 accaattctt ctctttcaag gtccagcgtc cagcagctaa gaccttgata gcgtccatct
     6121 cgactggcaa aggcatgggc cccagcttcg atggcacgcc agtcattacc agtggcaatc
     6181 aaaatcgcat caataccatt aaaaattcct ttattatgag tagcagctcg gtaaggatca
     6241 gcctgcgcaa actgactagc caacgcaatt ttctccgcaa tctctcgtcc ttgatccttt
     6301 tggcggctca agtagcgaaa ggcgatgcga cagcttgcag tcaccagaga atcggtcgcg
     6361 tagttggaca ggattcccat gagactctgt ccctgactga gttcttctaa gactggtttc
     6421 aaggcttcca gcatggtgtt gagcatattg gcacccatgg cttcctgggt atcgacatga
     6481 atataaacaa cgagaaagtc tggttcgcct tttatctgct cgacatgcag atcacgcgcc
     6541 ccacctccac gtttaacgat agaaggatag gcttgattgg caagctccaa gagctccgct
     6601 ttcttgctgg caatcttctc ttgcgctagt ttaggattag caacttgata aagggctacc
     6661 tgcccaatca tctgtcgctg atggacttgt gcagtaaaac cacctgcacg cttgatgatt
     6721 ttgctggcat agctggccgc cgcaaccaca gagggttctt ctgtcacata gggaacggtg
     6781 tattcctgac cgttgacaag tacctccgga accagtgaat aaggcagaga aaaagttccc
     6841 actacattct cactcagctg gtctgccaca gtcacgctca tctgttcatc cttctccaga
     6901 ctagcttgtc tctcaggact aaggagcgcc tgagctttta acagctcgag gcgctcttgg
     6961 tatgattttt tagaaaatcc attccaactt atcttcatta tttttcaacc ttgctataac
     7021 ggcgttggtg gtcgagaatt tcaaccaagg caaaatcttg attttcatag ccagcaaact
     7081 gggcagagtt agtttcatcc aagtttactt cctcaaaaaa gaccttttca tagtctgcaa
     7141 cggatagggc agttcgttgg ttgagcttgt tcaaacggtc tttatccaaa taagcttcat
     7201 atccttcaac caattcacca ctgaagaact cagccacagc tccacttccg taactataaa
     7261 gggcgatttt atccccagct ttcaagctat ctgtattttc caagagagac aaaagtccaa
     7321 ggaaaagtga acctgtgtag atattcccca ccttttgact gtagagaata gactggtcaa
     7381 aatgcttttg taagaggtct tttttctctt gaggcaggct cttatccatg atttttttca
     7441 agccttttag cgctaattta ggataaggca agtggaaaca aacagccgca aaatcatcca
     7501 aagtaagctg gtagcgtttt tgatattcaa gccaagtcgt tttcaaacta tccaagtatt
     7561 gttgggtaga atagacacca tttacataag gagttgtcga gtaatttggt cgccagaaat
     7621 ccatgatgtc acgggtctga gctacattgt cattattaaa ggccatcatg cgtggatttt
     7681 gtgtaatcaa catagctaca cttccagcac cttgagttgg ttctcctgga gtttcaatac
     7741 cgtatttggc aatatcactg gcaatgacca agaccttgga ctccggagaa ttttccacat
     7801 gcaatttggc ataatggagg gcagcagtcg ctccgtagca ggcttcttta atctcgaaac
     7861 tacgagcaaa gggctggatg cccagcaagc catgcacaaa gacggccgca gccttactct
     7921 ggtcaattcc tgactcggtc gccacaatga ccatgtcaac ttcttgtctt tcttgctcag
     7981 ttaaaataga gtcactagca ctggccgcca aggtcacgat atcctcagtt aggggcgcaa
     8041 tactcaattc cttgagtaag agtcctttac ttaatttttc agggtcaatt cccctcgctt
     8101 ctgctaagtc ttgtaatttc aagacatatt gactggtcgc aaaaccaatc ttatcaatac
     8161 cgattgtcat atttacctct gttttatcat tcatgtaaaa aatcgttcta tactatttta
     8221 tcacaaatgg cagtaaaaga gagaaaaaag acttgattca ccaaatcaag cctcttattg
     8281 gtcatcattt taaagaatga ttagttgcta gagagttcac cgatataagt agctttataa
     8341 gctccattca cagttatcag ctcctggagg atcaaatttc ctgagtaagt ccttcccatc
     8401 tcatctacaa atttttgata aaactgactg gtcggaattt ctctgacatc cttatcaaat
     8461 gtcttatcaa gtgttttact aaccttctca gcaatcaatt gatgctcttg ccatccactt
     8521 tgaaactctg agcccgaact agaaaccatg actgggataa acaacaaggt cagtagattt
     8581 acagacaata aggaaagtag tagacttcct gcaaaactag aatcctagtt catgattgat
     8641 aataccagca atcaaattca ttcgtaatcc gaagcgttta cgatgatttc gataggttgt
     8701 tgaaaacatt ttaaacgttt ttactttggc aaagatgttc tcaaccttgc ttctctcctt
     8761 agatagcgca tggttacagg ctttatcttc agctgttagc ggcttgagtt tgctggattt
     8821 acgtggagtt tgtgcttgag gatatatctt catgagccct tgataatcac tgtcagccaa
     8881 gattttacca gcttgtccga tatttctgca actcattttg aacaacttca tatcatgact
     8941 atagttcaca gcgatatcca aagaaacaat tctcccttga cttgtgacaa tcgcttgagc
     9001 cttcatagcg tgaaatttct ttttaccaga atcattcgct aattgttttt tagggcgatt
     9061 gatttttact tccgtcacat caatcattat cgtgtcctca aagctgagag gagttcttga
     9121 aatcgtaaca ccactttgaa caagagttac ttcaacccat tggctccgac ggattaagtt
     9181 gctttcgtgg ataccaaaat cagccgcaat ttcttcataa gtgcggtatt ctcgcacata
     9241 tagaaagcgt tatcaattta tttatctcat ttttcagaaa attcttttat ttctgtaaag
     9301 tctacgatac tcgatgtgtt tttatataat gatagagtct gagaatcact gttccgctag
     9361 ccattccaat agagattacc aaagccaaca tgacaaccaa ggtcgcactt gccagtgctt
     9421 tattatagtc ccctgtcaca aaaaaggcag ttgttcggta ggagagataa cctggaacca
     9481 gcggtgccaa aatggccaag ataaagacca cagcaggtgt cttataaaga atacttaaaa
     9541 tctggctgac acaagaacca ataatggctg caatgaaggt agctacaatg acattggtcg
     9601 gttccttgag caagagatag attagccaga cagtcatgcc caaaatccct ccaggtaaga
     9661 gcatagaccg ttgcacattg agtacgatta aaaaagtgat aatggcaaga aaacttgcta
     9721 ctgcttgtaa taaaaaggtt gttagtgtca tattagttca tcaataccaa ggcgacagaa
     9781 gttcctgccc ctaaagcgag ggtaatgagc agggattcaa acatcttact cataccagag
     9841 tttatgtggt tggtcataat atcacggacc gcattggtca aggcaatacc tggtacaaac
     9901 ggcatgaccg caccagctat aatcaaatct gccgttgaag gaaaacctgt gtagcgagcc
     9961 caaaactggg caattatccc aaagacaaag gctccagcaa aggctgtcac aaagggaatt
    10021 cggataaatt tttccacata gagggaaaag gcaaaaccaa ataaggtcgc cactcctgcc
    10081 ccaagtgcgt cgtagatatt tccgctaaac ataactgaaa agaaaggagc actaaaggtc
    10141 gcagccagag ttacctgcaa cttagtatag ggaaggggtt tggcttgcaa ggccgtcaat
    10201 tgcttaaagg ctgtttctaa gtcaatctgc cccccaacta gctgacgaga aatctggttc
    10261 acatcgcaga ctttttcgat gttataagaa gaggaggtca cgcgcttcat gcgcgaaata
    10321 ttggtatttt caatagagaa aaagatagcg gcaggcatgg caaggacatt gcaatccaca
    10381 atcccctgcg aatgcgcgat tcgaatcatg gtatcttcta cacgatggat ttctgagcca
    10441 cttttaagga gaatagtccc cgctagcata atcacatcaa tgacggcatt taattctttt
    10501 gattcttcca tgctttcctc cttttatcaa ctccctctat tctatcacaa atccggactc
    10561 aaaaaaaatc tttgccatga aatcatgaca aagattgatt actcattttg attatccatc
    10621 tgcttttaag gagtagctga agttgtttta ggtttgtaga ttgaaatctt gactctagtc
    10681 ttattgaggt ctaccttttc acctgctcta ggactttgtt caacaaccat gccttctgca
    10741 ctacctgcag gcgctgtcgt cacttctaca acttctatat tagcttcctt aatcccaaca
    10801 atttgaatca aattgttctt agtaaactcc aagctagaac caatgtaact cggcatggca
    10861 acacttgtaa cttttttagc tactgtcaag acaatttgag taggtttact cacatcataa
    10921 gtcgttccgg cacctggact ttgtttcata atcgttcctg gttcgctttc gctggactct
    10981 tcttcctcta tcttaatcaa attctcagga accttcttct gcttgagttc tgagattact
    11041 tctgtagagt tccgtccaat atagttccct aattgaatcg tcgtagcttt tttagctact
    11101 gtcaaaacaa tttgagttgc cttgctcaag tcataggtcg taccttctgg tagactttgc
    11161 ttcaggaccg ttccagcctc actctcattc gactcttctt cctcaatttt aatcaaatta
    11221 tctggaactt ttttctcttt taattccgca atgacatcag aggatttccg accgacataa
    11281 ttactaattt ggaaagattg cttgcctgat gagacaacca aattgatttt cgttccttct
    11341 tttcgaccag ttccagcgcc aggatctgta cggataatcc gcccttcttc caccttttca
    11401 ctagcctctg tcttctcctc accaatctca aaattggctt ttttgagcgt tgccttggcc
    11461 tctgcaactg tctgacctgc cacatctgga atggcaatgg ttgcaggagt tctggatagt
    11521 atccaaataa gagaagctgc caccaataca aggctggcca acaaaatcag gtaacgcatc
    11581 ttaaatctat gttttttcgg tgcttgtggt tggtaagttt cctctgtcac agcctggctt
    11641 gggtttttga ttgatttgtg ttctgtttgc gcttgaacct taggaataga tgtcaaggta
    11701 ctctgagaaa ccttcggcaa ggtcttggta tctgccttgc tcgtttcatc aaagattaac
    11761 ttactttcat ttctacgatt gtaggacaag ctactagaca agtccacata catctctgaa
    11821 accgagcggt agcgattggt caacttttta gcagttgcct tgataataac attttctaaa
    11881 gcctgaggta cagatggatt ttctgcaata acggacggca ggggtttctg gaaatgctgg
    11941 agggcaatgg tcaccgcgct atccccgtca taagggatat ggcctgtcag catctcatag
    12001 aaaataatcc ccatggcata gatatcactc tgcacagtcg ccttcgaacc acgcgcctgc
    12061 tctggtgaca agtaatgaac tgagcccaac atcgagttag tctgggtcag acttgtctct
    12121 gcaaaggcta cagcaatccc aaagtctgtg accttggcag tcccatctgg tgtcaagagg
    12181 atattttgag gtttcaagtc cctgtgaaca attcctcgag tatgggccaa gcgcatagcc
    12241 aagagaattt gtcccatgat acggactgct tcttcattag aaagaggata atgttccttg
    12301 atatagcgtt tgaggtccag tccagccaca tactccatag ctaggtactg ttgaccgtct
    12361 tcctcgccaa tatctgttat ccgaacgata tgaggatggt ctagatctgc catagctctc
    12421 gcttcacgct gaaaacgagc tacagctatc gggtccgtct ggtagttggt cctcagaacc
    12481 ttcactgcca cttcttcccc atctaagatt aagtctttgg ctaggtagac atccgccata
    12541 cctcctcgac caatctgttt gacaatccga tagcgtccgg caaaaatctt gccgatttgg
    12601 atcattctgc atcctcctcg ttcatagaaa caagggcaac cgtaatgttg tctaaacctc
    12661 ctgcattgtt agcaaaacga acaagtgtct ccgttttatc tgctaaagga atatcactgg
    12721 ttacaatatc acgaatctca ctgcctgaaa tcatgttggt caagccgtca ctattgagca
    12781 agagatagtc acctgactca aggataactg tcccaaaatc aggctgaatt tcatcttttt
    12841 gcccaataga ctgggtgata atattttttt gcggatgagc ttctgcctct tctggtgtca
    12901 attgaccagc cttgagcaat tcattaacca aggaatgatc gctcgtcaac tgatggtatt
    12961 cttctccacg aatcaagccg atacgcgaat caccaatatg agcatagata gcctgattat
    13021 caataatagc aaggacttcc aaagtagttc ccatgcctct gtaagcttca tcctgaccaa
    13081 gctggtgaat cttttgattt tcaatttcta ggtaatgggc gaaccattca cgcacttcat
    13141 tgactgtatc gatctgggta tcaacccaag ctacacccag gtctgtgacc gccatttcac
    13201 tagcgatatt ccctgcgcga tgacctccca tcccatcagc taaaataatc atggtacgtc
    13261 cagctctatt gacatagtgg ttgacatagt cttggttatt tgttcgtttc tgaccaacat
    13321 ctgttaataa tgaaatttcc atgtgtcagt tccttcctaa tccgatatct tgcgaaattg
    13381 actgatgaag aatccatcac ttccatacaa ttcaggtgta atgaggatac agccgtcttt
    13441 catgatatcc ttacattcat gttctagttt tacctgctcg aactcgggat gactctctaa
    13501 aaaggcctta acgacttgaa aattctcctc tgagacgata gtgcaggtgc tataagttat
    13561 tataccacct ttgcctagta tttgacaaac actacctaat atttctaact gaatttcctg
    13621 caaggacgcg aaatctgccg tttctttatt gtatttgata tctggttttc ggcgcaaaag
    13681 accgattcct gaacaaggag catccaccaa aatcttatca aaggaatcct ggtcaaaaaa
    13741 ctcatgcacc tttctggcat ccaatttttg agtttgaacc cgatcttcaa ctcccagacg
    13801 ttgggcattt tcttgaatta aatccaactt gtggtcgtac aagtccagag cagtaacctg
    13861 acctgtcgta agataagagg ctatatgggc tgttttccca cctggagccg cacaggcatc
    13921 aagcactcgc tcatcacctt gtaaatcaag cgtcggagca accagctgac tggactcatc
    13981 ttggatggta atggctccat ccgcaaacaa attatgccct gcaaaatgcc cctgctcctt
    14041 aaccagacca gtggttgcta aaagggaatt attcgcctcc aacaaggctt ggatttcctc
    14101 ttttcgactt aggtctgtta cacgaatact ggctttgttt cgcactaaca ggctttcaaa
    14161 gatggctttt gctctctcct ctccgtattc ttccttgagt ttggcaacta gccaaactgg
    14221 gagagaatag gcaatggagt cacgcttgtt ttttcgcttg atgctagcaa tatctggcca
    14281 gccttcacgc aagatacggc gaaggacagc gttgaccaat ttttcactgc cttttttacg
    14341 gagtttggcc aattccactg cttcattaac cacagcatga tctggaatct tgtccaaata
    14401 gcggagttgg taggcactca tgagaagaag gacatagagc cagctgtcta actggtctct
    14461 gtcttcgata aagtgggata ggtaccattc cagagtcagt ttacgggcta ccgttccata
    14521 gaccagctcg gtcactaagc ccttgtctgc tgccaaaagt tgacttccct ttagatgctt
    14581 atttaaggcg atatttgaat atgcttggtt cacaaaaaca tcctctagca ctgctagagc
    14641 taaacttcta gccgtttcta ctttagtcac caaatcgttc tcctacagtc aatgtacgtc
    14701 caactccgtt gaggaaggaa gcaatgtcca tcttaggctt accagctggc tgcacttgtt
    14761 tgagggatag agccccttca gccgttgcga caatcaattc tttcttgccg atagagagaa
    14821 tctcacctgg atttccctga ccttctactg gtagggcttc ataaatctta aagcggtcgc
    14881 ccttaaggaa agtatgggca acaggccagg ggttcattcc acgaatttgg ttaaagagtt
    14941 gacgattggt tttgttccag tccagttttt cttcctctgg ctttatattt ggagagaagg
    15001 taacctgact cgtatcctgc ggttcaggtt tgatatcacc agcaatatag gcaggcagag
    15061 tgtccaaaag caaatcacga ccaactagcg ccaatttttc aaacaaggtg ccaacattgt
    15121 cctcatctgt gatcggaatg ctgcgacgag aaatcatatc tcctgcatcc atttccttaa
    15181 ccatttccat gatggtcaca ccagcttcct catccccttg aatcaaggca taatggatag
    15241 gcgcaccacc acggtgtcta ggaaggaggg aggcatgaac gttgacagca aagtccatgc
    15301 tatcaaggag tttgcttggg agaaactgcc caaaagcagc agtcacaatt ccatctgctc
    15361 ctagcttcat aagatcttcc atctctggac ttccagataa tttttcaggt tggtagatag
    15421 atagtcctgc ttccttggca gcctgcttga ctggggtttc ttggataact tttttacgac
    15481 caacagcacg gtctggctgg gtcacaacgg ctagaatttc gtaacggtca tctgtcaaaa
    15541 gtccttttaa gactgttgct gaaaagtcgg gggtccccat aaagattagt tttgtcatat
    15601 cttctccttc ttataaaaat tgctgcggct catggtcaat gctgagacgg agctcactat
    15661 tttcccgttc ttgagtcaag gctaaaacct ggttgagggt cgaccccagc tcatcttcta
    15721 aacggtattt aattaaaatc tggtaatgat agaggttgtg ggtacgggca atcggttttg
    15781 gcgttggccc cagaatggga ctggtctctg acaagcctga ccgcaaaatg ttcatgactt
    15841 cataggcacg tttgaaaacc tcttcttctt tcttgtgaga aagggtaata ccaatcgtga
    15901 aatagtaagg tggatagccg agttgtcgtc tgattcccat ttcataggca taaaagcctt
    15961 cgtaatcttg atccttggca aatcgaatag catagtgctg cggattgtag gactgtatca
    16021 agacttgacc tgccttttca gcccgacctg atcgacctgc cacctgagtc aagagctgga
    16081 aggttctctc agaagaacgg aaatcaggca gattcaaggc cgtatccgca tttagaactc
    16141 cgactagggt aacattggga aaatccaaac cctttgcaat catctgagta ccaagtaaaa
    16201 tatccgcttc ccctcgccca aactggtcaa gcaaggcttg gtgactgcct ttctttcgag
    16261 tcgtatccac atccatcctc agaatgcgag cttggggaaa gagttctgct agctcatcat
    16321 aagccttctg agttcccgtc ccatagtaac gaatactgcg gctcttacag ttaggacaga
    16381 cctgaggaat atccttcgag aaaccacaat aatggcagtt catagtcttg gtatccatat
    16441 gcaaggtcag agaaatatcg cagttgggac aagtatccac cgtcccacac tcccgacaca
    16501 tgacaaagct agaataacca cggcgattga gcatgagaac cacctgctct tttttaacca
    16561 gacggtcttg gatagcctct agcaaaggag gcgtaaagtt tgacgtctca ttttgtccga
    16621 tatagtctcg aaagtcaatc acttgaacct cagggattgt agccaaagga ttggcacgtt
    16681 gggttagacg taagtgttga tagacgcctt tgccagcacg tgcccggctc tctaagctcg
    16741 gcgttgcaga tccaagtacc agagttgctt gattatactg agcccgtaaa atagctacct
    16801 ctctggcatg gtaacgggga ttgctgtcct gcttataagc cgcttcatgc tcttcatcaa
    16861 taatcatgac acccagattt ttcagaggag caaagatagc agatctggca ccaacaacaa
    16921 cttgggcatc gccacgctcc accttgcgcc attcatcata cttttcacca ttggataatc
    16981 ctgagtgaag aatggctacc ttgtccccaa aacgtgctat aaaacgctcg gtcatctgag
    17041 gagtcaagga aatctcaggt accagcaaaa tagctgtctt gcccttatcc agggcacctt
    17101 ggataatctg caagtaaacc tcggtcttcc cacttcctgt aatcccttga agtagaaagg
    17161 gaggttgaga actgccaata gaactcacaa ccgcatcacg cgcctgtctt tgttctggat
    17221 ttaactccaa aggtctactt gcttcaattc cttcaaaata agcagccgag cgttgaactt
    17281 ccttttggac tatggtaaca gcaccttgat ccacaaagaa gttgacttgc tctcgcgagt
    17341 aggactctaa caagctagcc aaggaagcgc tctctggatg agacagcaga taatctctca
    17401 gttccaactt tttcttggca cgtgtagaaa tctcaacacc ttctaattga gcatggtcaa
    17461 cctcatacca agactgggtc ttgaccttct tttgatcgac tgcctgatat tccagaccaa
    17521 gcaggccttt tctagtcaaa cgcatcattt cagcttgctt ggcaaggtct agtgaagaaa
    17581 aggctagcga atcttctgaa ccaaacaggc gcactcgttc ttcctgactc aagccttcca
    17641 gaggatagag aatcttgtca tagctagaat tcagaaaccc tggaagcatg gccttgagga
    17701 tagagatttt gtaggagaag acagatttgc gtaactcctc agccagccag agttgttctg
    17761 gcgtgagaac aggagaaaaa tccagcacct ctgcaatatc ttttaaatct tgctccatct
    17821 cttctccatc tgattgggac ttcaaaccaa gaacaatccc ttgaatcagg cgattaccct
    17881 taccaaaagg cacatgaacc cgcatcccaa cttccagcat tccctcaaat tcctccggaa
    17941 tcctgtaact atagggctgg tccgtctgca tcaagggcac atctacgata atcttagcta
    18001 gggccatctt ctcacctcct ccttgtcagt acattcttgc aatagaaaaa ataagattga
    18061 gtccccccaa ccttaaattt tttcaccatc ttctttttct ttagcaattt gctctttgat
    18121 tttcttttct tcttcttctt tgcggcgttt ttcttcttcg atacggcgac gcactgcttc
    18181 acgttttcct tctggatctg ggtgaattgt aacgtttcct gattcgattt cttctaaagc
    18241 gcgaagagtt gatttttcag acttgaaacc ttgagttgct ggggcacctg cttccaattc
    18301 gtgggcacgt tttgcttcca agattacgag tgaatatttt gaaggaacct tgtcgagcaa
    18361 ggtatcaata gagggtttta acatcatttg cttgtaccta ttttctaaat tttatcgggt
    18421 agttggagat tttggtaaca tctcctgata gtgaccaatg acacgatcca cacagaagtg
    18481 ttctgcttca atcacacatt tgacacgttc agcagctagg ggtacctgat cgttgacaat
    18541 cgcataatca tactcacgca tgagggcaat ttcttccttg gccttttcga ttcgttgggc
    18601 aatcacttct gcactatctg ttccacgacc taccaagcga tcttgcaatt catccaaatc
    18661 tggtggtgtc aggaagataa agacagcatc tggaaccttt ttcttgacct gaagagcacc
    18721 ctgaacttca atttcaagga aaacatcgat tcccttgtcc aaggtttcat tgacataggt
    18781 cagaggagtt ccatagtagt taccgacata ttctgcgtat tccaacatct gtccttgacg
    18841 aatcagctct tcaaattctt cacgagtacg gaagaaatag tcaacaccgt ccacttctcc
    18901 aggacgttgt gcgcgtgtcg tcatcgatac agaatattga aattggtttt cagaactctc
    18961 aaaaatctct cttctaaccg ttccttttcc aacccctgaa ggaccagaaa aaacgattag
    19021 taagcctcgg tctgccattg tgtctccttt tagtcaatct gtgaaataac atttctctag
    19081 aataatggca aaaagccaga ttatccttta cagtctttct atctagtgta acaaaaaagc
    19141 agtaattttt caactgctct ttcttattta tttagcataa tctactgcac gaagctcgcg
    19201 aatcacggtt accttgatat ttcctggata atcgagattg ttttcaattt tcttacgaac
    19261 tttgtgagcc aagattgtga ctttgtcgtc cttgattttt cctggattga ccatgatacg
    19321 aatttcacgt cctgcttgaa gggcaaagct agtttgcact ccttcaaagc cgttagcaat
    19381 ttcttccaaa tcatggagac gcttgatgta gctttcaaga gactcactac gagcacctgg
    19441 acgggctgcg ctcaaggcat ctgctgcagc gacgataact gctatcacgc tctcagcttc
    19501 aacatctccg tggtgactag caatcgtatt caccacaact gggggttcct tgtacttacg
    19561 ggccaattcc ataccgattt caacgtggct accttcaacc tcatggtcaa tggctttccc
    19621 gatatcgtga aggaatccag cacgacgggc aagagccgca ttttcaccaa gttcgctcgc
    19681 catgatacca gccaacttag caacctcaat cgaatggcgc aaaacatttt gtccatatga
    19741 agtacggaac tgcaaacgtc ccataatctt catcaagtct ggatgaaggt ttggcgcacc
    19801 aatttcatag gcagcagcct caccgtattc acgaatctta ttgtcaatct cttgacggtt
    19861 tttctcaacc aactcttcga tacgagctgg atgtatacga ccatctttga gcaacatttc
    19921 catagtcata cgggcaatct cacgacgaat cggatcaaat cctgacaagg tcaccacttc
    19981 tggtgtatcg tcgataatca catcgacccc tgtcaaactt tcaaaggtac gaatgttacg
    20041 accttcacga ccaataatgc gtcccttcat agtatcgtct ggcagatgaa ctgttgagtt
    20101 tgttgactcc gctacatatt caccagcgat acgttgcata gcttgaacca agatgtcctt
    20161 ggccattttg tcagaacgtt ccttgacctc ttgctcagct tcgcgaatgc gactggcaat
    20221 ctccctggtc aagttttcct ctgtctgagc caagataata tctcgtgctt ctgcctgaga
    20281 cagcgcacca atacgctcta gttctgcttc tttttgtctt tcgacttcct ctaattgctc
    20341 ttcacgcgca tcaaggtttt tcgctctatc agaaatactt tgttcttttt gttcaagtgt
    20401 ttgttcttta ctcgtcaaat tgtcgtcctt acggtcaagg ctagtagctc tctctgtcaa
    20461 acgactttcg atttgtttga gttcttgacg ttctgatttg aattcagcgt ccacttcttc
    20521 acggtatttt ctggcttctt ctttggcctc caatagtgct tcttttttaa gagacttgct
    20581 ttcacgtttg gcttcattaa caagtaaatc cgcttcacgc tcagcttgtc cacgtaaatt
    20641 agttgcttct tgttcagcat ttaaaagcat caactctgca gcttcctgag atgatttcat
    20701 cttagctgag atgctgacat atccaatgac taaaccaatg atgacggcaa aaacagcaat
    20761 cgcaagcgac atgatttcca tgtttttacc tcattttatt gttattccga atgacataca
    20821 ttcttttaca ttctaccata aaaaagtgat tttcacaaac ctaaaataga atatgttttg
    20881 aggaatttgg aacacattta ccaaaataaa cttgttgttt agaaatagta gtttagtaga
    20941 gacttgagaa aaagcctacc tttcaataga cttagtaatg atctttaaag gacaagaaag
    21001 ccacgctatc tccatccatc atataaatca agcgattttc tgcatcaata cgccgtgacc
    21061 aggctccttg gtaatcatat ttgagtggtt ctggtttacc tattcctgta aagggatcac
    21121 gttgaatatc cttgattagt ttattgattc tttttaacgt tttcttatcc tgattttgcc
    21181 agtagcaata atctgcccag gcatcttctg taaacttgag cagcatttct tactcctcaa
    21241 taacatggac ctgagtactt ccagcacgaa cttgagccat tcctcgcaaa accttatcag
    21301 aaagttcctt attttgagca attctcaggg tttcttggat actatcccac tcactctttg
    21361 aaaggactac aatgtcctca tctggatttt tattgaccac cgtcaaaggc tcaaattcat
    21421 catttacctt cttcatgtag tcctttaaat gatttcggaa tgttgagtaa aggactgctt
    21481 ccataaccat acctcgtttt agctcttttc cactattata cacgaaaaga aagaaattgt
    21541 caggaacttg tacaagattt tcttttctat ctatttatac tcaatgaaaa tcaaagagca
    21601 aactaggaaa ctagccgcag gctgtacttg agtacggcaa ggcgacgttg acgcgatttg
    21661 aatttgattt tcgaagagta ttattcgtaa aaaatctcaa aaagcctacc tttcggtaga
    21721 cttagtttgt ttctattcta atcggcactc ttccaaaatt ttgctctgct atacttggct
    21781 tccctagttg gtaaatctgg tctgcttttt gggtcatagc atcccaaggt tctttgccaa
    21841 ttcggctgac tagactgacc tgacctttca aagacttgag atgttgccta cctttttcag
    21901 taaatccaag gacatgaatg gcttctggca agtcactttc tctagcctgc atcaaaatat
    21961 aggtcaatag gcgtctgaca cgcgccttgg tgtaacgttt ggtagtcact aactcgacca
    22021 attcttccac agactgggct gttttaatag cttctttaat gcgcacagcc atttcttgat
    22081 tgacctgata gatggtggtt aggtcgggat ttgacaagat ttgatagcgg agcaagggaa
    22141 aatagtcttc ccagatcacc ttactggcct gctcaaatag ggcaacagaa ggcataaaac
    22201 gttctaagaa atcttggtcc ttctgatgtt gacggagggc tgtcgccgag gcaaagtcca
    22261 catctttatt cacagaatgg taacctgccc cctgacgctg aatcggatgc agcttgatat
    22321 tccgtcctgc aaccgccttg gcataggcca gagcaagaac atgattgggg gtattatctg
    22381 aaaaatcaag accagcaaat tccttccaca tagcttgggt tttctgggga taggaaaggg
    22441 aatcaggcag attttccaca aatttctcca tctcagcacc tttctctgtg tataagtcag
    22501 caattttctg ataatctcga acttcctctg tcccaaaaac tagactatca atgcccaagc
    22561 gatccaagat atccatagct ccttgaccaa agaaatcagc tgcctgaaca ctgactaaaa
    22621 agggcaattc cactaccaag tctgcgccat tttccagcgc catctgggtc cttgtccact
    22681 tatccacaat agcaggctct ccacgctgca tgaaattccc tgacatggca acaattttca
    22741 gtccctctgc ctgatccagc aggtatttat ggccattatg aaaaggattg aactccgcga
    22801 taatacctgt tatggtcatg ctaatctcct acttctgcgc cacaaaaaac caacgggtgc
    22861 tagtttctgt tggctcctta tcctcaaagt ctgcatagag tttgaaggac ttaaatccag
    22921 cctgttccag caagatatca taggtcaaga tctcataggt cctctcctca tgtacttcat
    22981 cgtggcgact aaaggaaccg tcagcctcct tgataaagaa agtcagctca tgcacgatgg
    23041 agtgaggaac ttcgtcctca tatgtatccc aaagcatggc aaaatcttcc gcattttcat
    23101 ggtaggaata gccagggaat acttcatctg tctggtaggt cgagtgcacg tcaaagatga
    23161 aaactccctc ttcattcagc gcattgtaca cgtccttaaa gacgtcccct acttccacct
    23221 catcctgcat atagcagata gagtccgaat aacacgtgac aaaatcgtat ttccctgcct
    23281 tggacaaatt cagcatatta ccttctataa aagcaatctt ttgcttggct gaagttgctc
    23341 tcttctccgc aatcttcaac atatccgcac tcaagtcaag tccagtcaca tcaaaaccag
    23401 cctgagagaa gcgcactgat tgaattcctg tcccacaagc caattccaag agtttctttc
    23461 tctccttggt cttaggcaaa tgacgcagag aaaaattcgt ccatttgtcg tataaactat
    23521 cgtccatgac cgcatcatag accgccgcaa aggtttcata agtcgccata atcatgatac
    23581 taagagctcc atggtaaaca ccactagccc tttacctttc tatcaatttt tctaaaataa
    23641 gcaaagaaac ccagttgact acaactgagt tcatcttcta agcaagagct tctgaaatat
    23701 ctactgaatt cgcctcatgc catagcttct ctagattata atgggcacgc atttcttctg
    23761 aaaagatatg cacgacaaca gcaccgaggt ccagtaagac ccagcctcca gctgcatcgc
    23821 cttcgacatg gctaccttta aagcctgctt gagctacttt ttcacggata ttagctgcga
    23881 tagcgtccaa ctgacggcta ttcattgagc tagtgatgac caagtagtcc gtcacactag
    23941 tcaaatcttg tacatcaagt gcgaggatat cctccgcacg tttctcatca gccgctttca
    24001 cgactagttc tagtaattct ttttcgttca tttaatcctc tttttagaaa atatgtttgt
    24061 aatctagaac atctgcaaag cgctcctccc aaatgtcctc ataaaattca ttaatcgttt
    24121 ctgctggaat gtcatcccca tcaaaggttg tgacagcacc ttctggaaca ataagctgat
    24181 agccatattc aaaggcaacc ttgacagagg tatccacaca atattctgtc tgcataccac
    24241 ataaaactaa tttttcaatc ccctgcttat ccaagtattc ttttaagcca gtttctttga
    24301 aaatactgtt atacttcttc tgaaagacct tttcagcagg ttttcgattt aaaagcgcag
    24361 ataactgcca atcttctgat gtttgagctt cagagttctc aatatgttga acatagataa
    24421 tttcaatatt cttgcttcta gcctggtttt gtaaataaga aattttttcc aatagacttt
    24481 ttgtctggaa cccagtttct actaaaacat tctgaacatc aatgattata aaagccgtct
    24541 tcatttagtc ctctttcaaa tagtgcacaa aggcgttata ggtttcaagg gtttggggat
    24601 agatggggaa tccctgatga gctagatact ccacggtacg agctgtttcg taggccaccg
    24661 ccttattgag cgatagactt gcaatctcac gcgccacatc tactccagga aaggctcgat
    24721 tgtgctcgat atagtctgcg acgtagatga ccttatctag gtctgtcatt tgaccagctc
    24781 cgactgtatg aatttcaatg gctcgcagaa tttcagaatc atgcaaatcc aaatcttcct
    24841 gaattttgta aattccgacc ataccatgcc agacattatt gccccagttt ttgaggtcag
    24901 ggtctagctg gtaacggtca atcaagacta gaaattcctg atctgacaac tttttagcat
    24961 agtcatgaag aagacctgct agacttgctt tctcaacatc tacaccaaag cgctgagcta
    25021 attccatagc ggcacgctcc acacctagac aatgggttag acgtttctca ggtagaagct
    25081 ctgccatttt ttccaacaag gcctcacggg agcagttgat atagtcttga taggacatca
    25141 gtagagccct tccttctcga tgtagtctag cactggctga ggtaggagaa agttgggttt
    25201 ccgaccttgg gcaaggaagt cccgcaccat gctggacgag atatccatga gcggtacgtc
    25261 cacccagata actggatagg aagtccctac cttgtagcgt ggacgctgaa cccccacaaa
    25321 ctgaaccatg tcaaccagtt catcaattcg gtaccactta ggcagatagt caaccatgtc
    25381 ggcaccgatg ataaagtaat aatccgtatc tggattcttc tctgtcaaaa tcttcatggt
    25441 gtcgtaggtg taggaaatac ccttgcgctc caactcaatg gtttcaatga ctaggccgtc
    25501 aattccctca attgccaact caagcatctt gagacgatgg tgttcaggga tggtttcctt
    25561 tttatcaacg tgaggaggtt ggtattcagg catgagaaga acttgatcca gtcccaactg
    25621 ttgccgtact tgatccgcaa caatgagatg ggcattgtga acagggttaa aattcccccc
    25681 taaaatccca acttgtttgc gttttttctc cttgatttct ggctccaact ctaccttggt
    25741 aaagggagtc aatagttcga ttgtcatagg ctagtcccct ttatttctct ataaaaacag
    25801 ttatttggag tttcggtctt agatttcttt gactttctta gaaatcttgc gattttcttt
    25861 cttgctagat tgtttaaaca aaatcaagat gcgtcctatt ttttggactg tatccacacc
    25921 gatttcttct tccaaaattt cagctacttc gtggatgttt tcatctgtgt tttgtaagag
    25981 agtaaccttg attaattcac gcgcatcaag agcttgacgg acgctggttt tgatttggtc
    26041 gttgagtcca tttttcccga tttggatgat aggtttgagg gtgtgtgcct ggctgttgag
    26101 gaaggcacgt tgttttgatg ttaatgacat aattttcttc cttgtttttt gatagttatt
    26161 ttaggtggtg agggacggtc ggaactaatt ttccaaagat ttcatctttg aaaaatggat
    26221 ttcctgacct cacaattgag tcttggtctc aattgtgccc cttgccaatc tacagattgg
    26281 caatcacacc acagcaataa ctatcgctat atgagctcac tttgttcgct cagcgatttt
    26341 gttttaaata attgcttttc gtgtgacgac ggcgacgcct tctggtgccc agacggcgac
    26401 ttttgctatg cctgttacac gaatccatcc taggcctgag ataactaggt ctgtcttatc
    26461 tttaatggta aagacatgct ggactagcct tgggaaatct tctttttcct tgctatttgg
    26521 tggtgtcaga agagttccca ggtgcttatc gtagaaagca ctagctcctt caagcttgct
    26581 acgatggagt ttgagttcat tatcaaagaa agcagtaaat ccttgctttt ctcctgctat
    26641 aaagtcaaag cgtcccaaac cacctaaaaa tagggtttgc tcaggattaa gctgataggt
    26701 cttaggcttg atttcctttt taggactgac atacttgagg tttttggccg tcaagtagtg
    26761 agccatctgg tggcggtgga taattcccgg cgtatcgtaa atataagatc cgtcgtcaag
    26821 cggaatctct attttgtcca aggttgtccc tgggaagcgt gaagtagtga tgacattctg
    26881 atcacccgtg atttcttgga taatagcatt gattagagtt gattttccaa cgttggtcac
    26941 accgaccaca tagacatcgc ggcccttacg gtagtgttca atcttgtcaa tgacttcctt
    27001 aatggcatgt ttattttgtg ctgaagttag gaccacatcg actggacgaa gaccttcttc
    27061 atgggcacgt ttcatgagcc actggctaat cttaccagac ttaactgact taggaaggat
    27121 atctttttta tttcctacca agaggacatc attgcccgag acgaaacgtg gtaaacctgg
    27181 gatgacagat ccattaaaat caaagatatc aataacattg accactaaag catcactgtc
    27241 tcccacctcg tgcaagagct tgaggaaatc atcgttcgtc aactggacat ctgtgatttc
    27301 attgtagtgg cggagacgga aacagcgttg gcaatagact tcgccagtct ccaaaccttt
    27361 ttcaagtgcc gactgggggg taaaaccaag accagcttta tctgtcgtct gaatggttgc
    27421 tccacaacca atacagagaa tttcttccat agttaaattc cttttttata tgtaatcggt
    27481 ccgtactttt cagtgatttt tctcataaca cgacgctcac gagttcggtt aatctgcgtt
    27541 ttgattgagt catgttggac caagggtttg actaaaattg accgaatccc tgcacggtgg
    27601 gctgctcgta tatctgtcat gagttggtca ccaaccatga ccacttcctt tttgtcatag
    27661 tggaattcct tcatagcacg gtcaatacca aatgtgaagg gcttcaaggc ccagtaaacg
    27721 taatcaatcc caaatttctc aactgctcgt tgaacgcgtt ttttggtgtt atttgacact
    27781 acgataatgc caatacccgc gtcccgaagg tcatgtagcc attgcttcat ctctggcgtt
    27841 ccatcagggt tgttccaagc aatgagggta ttatccaaat cgaccaaaac agcctttatt
    27901 ccctgcgcct gcaggcttgg gactgtcaga tcatagactg cttccacagc aaaatctggt
    27961 atataatttt caatcgccat tctggctcct tttcttaact ttttttcgca attttcctta
    28021 gtaacaagga taaaacaatc cacaaacctg cactagccaa actgatatag agccaagcat
    28081 ggggctcatc tgttaaaggt aagggaacat tcattccgaa aaagcctgtc acgactgcca
    28141 aaacagctag caagactgaa atgatagtca aggttgtcaa attgtcattc agattattgt
    28201 ttagaatatt gttgtaagag gctgaaagct gctgtaaaat ctgagagatt aggtctgtca
    28261 tggataccag ctgatgagcc tcaatcatgg catcatcaaa ctgttctctc tcaatctcat
    28321 caaaactacg atacaaggca tgaccttgaa tatgctctaa caaaatccga ttttgtttgg
    28381 cagctgccgt cagataaacc ataccagtct ccaaatcaga caggacaaag aggtttttct
    28441 tggtagttcg ctggcgcaag aggtcattga cctcatccct actcttgtcc atctgctcaa
    28501 tgacaggata gtaggcattg ctgatgattt ccagactggc aaagagaaac ttataaatcg
    28561 aaagcgtgtc atggttctcc agataacgag tcatctgttc aatgacatag gcgttcttgg
    28621 tattactaat ggtaatcagg cgacgatgct cgacaataaa ggtcatggga aaagtctcat
    28681 agtaggcctt gtcctttttt acgtctaaga cattatagat aaaggtaacc gtctcacttt
    28741 cacggtggta gtccatgtgg gcgcgctcgt ttctatccag tgcgtattca atggtttcct
    28801 tgtccaaacc gtaaatttca gaaaggtctt ctagtttatt caactttcct aggtctaggt
    28861 ctatccaggt acaaccattg cccaactgct tttctaaaac catcttttct ccttattaaa
    28921 ctccctctat tgtaccacaa attacttaaa ataacaggtc tagtctgtgc gtgagaaatt
    28981 gctaacaact gtgatatttc ggttagggac aaagtgaagg gcttgctcct cgctacgaag
    29041 ctgtgtcgta cgaattccca cactgacaac cttacccgat acagtaatcg gtccatttgt
    29101 cagaacgacc tcatctccca catccagttg acgttcaaag aggatgaaaa agccattgat
    29161 gacatcagac agaaagcctt gggctcccat accaatcgct accccagcaa taccagctcc
    29221 agccagcaaa ctagaaactg gcaaacctaa aatcgacaaa atgcagtaga gtaaaaagaa
    29281 atatagcgta taattaaaca cattttctag taaacgtgag atggtttttt ggcgtccaac
    29341 atcatgacga gacattttta gagaaggttt gacaattctc tgcaccatgg tatgaagcat
    29401 ttttttagca atataaaata caattaaaag cagtaaaaga gaaatgacct tggttagaat
    29461 attctcgata atggttgtca catctagctt ttcaatataa gcctgaataa atttttgcat
    29521 ataaaactcc tttatttcat tataccatat tttcatcagt ctcattctcc ataaatattc
    29581 aaaaaataga cagaaaattc ttgattttgt ctatcattta tactataatc ataatcacta
    29641 cacaaaaagg agattattat gaaaagaatc attcatgctt ggaataaggc aagccttgtc
    29701 aagcgtatct tgattggtat gctttgtggg gaatcctagg actgaccctt cctaatctct
    29761 cagggattgg gctactcgag gatttattcg ttggaggtct aaaagctgtt gctcctatcc
    29821 tagtctttgc tctcgttgcc aatgcccttt cccaacatca aaagggacaa gatagcaata
    29881 tgaaaactgt tgttttcttg tatatcctat gatagggact ttcgccgctg ctcttgtagc
    29941 tgtactagca aatttcatcg tccctattga aattacccca aatagtgcca atactgaaat
    30001 tgcaccacca gatgggattg ggcaggttct cagcaacctc ttgctcaaac tggttgacaa
    30061 cccagtcaac gccctgctta ctgctaacta tattagaatc ttatcttggg cagtcatttt
    30121 tggaatcgct atgagagaag ccagtaaaaa tagtcaagaa ttgctaaaaa ctatcgctga
    30181 cgtgacttct aaaattgtcg aatggatcat caatctggct ccatttggaa tccttggtct
    30241 tgtttttaaa accatttctg acaagggagt cggaagcctt gccaactacg gtattttatt
    30301 ggttctatta gtaacgacta tgctttttgt tgcccctgtg gtcaaccctt tgattgcctt
    30361 cttctttatg agacgcaatc cttaccctct agtttggaac tgcctccgtg tcagcggtgt
    30421 gacagccttt ttcactcgta gttctgcgac taacattcct gtcaacatga aactctgcca
    30481 tgaccttgga ctcaacccag atacctattc tgtttctatc ccactcggtt ctactatcaa
    30541 tatggctgga gtagcgatta ccattaacct tttgaccctt gctgcagtta acactcttgg
    30601 aattcctgtt gactttgcca cagcctttgt cctcagtgtg gtagcagcta tctcatcctg
    30661 tgatgcttca ggtattgccg gaggttccct ccttcttatc ccagttgctt gtagcctttt
    30721 cggtatttct aacgatattg ccatacaaat tgttggggtt ggttttgtga ttggtgtcat
    30781 ccaagactca tgtgaaacag cccttaactc ttctacagat gtcctcttta ccgccgttgc
    30841 cgaatacgca gcaacccgta aaaaataact catcaaggca agcctgctca tgtcttgtct
    30901 tttacgcttt tattctaact tattaggaaa ttcttatgtc tattagccaa cgtacgacca
    30961 agctcatctt agctacctgt cttgcctgcc tgcttgctta ttttctcaat ctttcgtcag
    31021 cagtttcggc tggaattatc gctctcttga gcctatctga tacgcgtaga agtactttaa
    31081 aactggctcg caatcgtctt ttttctatgc ttctagctct ggctatcggt gttctagctt
    31141 ttcacttgag cggatttcat atctggagtc tcggcctcta tctggccttc tacgttcctt
    31201 tagcctacaa gatgggctgg gaaattggca tcacaccaag cactgttttg gttagccatc
    31261 tcttggttca agagtcaacc tctccagacc ttctagtcaa tgaattcctt ctctttgcta
    31321 ttggtacagg atttgccttg cttgttaatc tctatatgcc ttcacgagaa gaggaaatcc
    31381 agcactacca cacgctggtg gaagaaaagt taaaagatat cctccagcgc ttcaaatact
    31441 atttatccag aggagacgga cgcaaccgag cacagctggt agcagaatta gacacgcttt
    31501 tgaaagaagc cctcagactg gtctatttgg atcactctga ccacctcttt caccagacag
    31561 actaccatat ccactacttt gagatgagac agcgacaaag tcgtatcctg agaaacatgg
    31621 cccaacagat taacacttgt caccttgccg ccagtgaaag cctgatctta gcgcaactct
    31681 tttcaaaaat tgcaggtcaa ctgagccaga ccaatcctgc ttctgatttg ctagatgaaa
    31741 ttgaacgtta tctggaagtc ttccggaacc gcagtctgcc caagacaaga gaagaatttg
    31801 aaacccgcgc cacccttctt caactcctac gtgaagccaa aaccttcatc caagtaaaag
    31861 ttgattttta ccaaaaatat agacagtaat actcttcaaa ccacgtcagc gtcgccttgc
    31921 tgtatatatg ttactgactt cgtcagttct atccacaacc tcaaaacggt gttttgagct
    31981 gacttcgtca gttatatcta caacctcaaa acggtgtttt gagcagcctg cggctagctt
    32041 cctagtttgc tctttgattt tcattgagta taaaaaagaa aacttcagac caatccacaa
    32101 aaggtgaata tctgaagttt tcttttattt ataagtaatc accataaagg ttaatagtag
    32161 aataaataaa gccaaactca ccaataaagt gagcaccttg accaaggtgt tgctctgcca
    32221 gtagcttggt ttaccaatat tactagtggc atccatggaa aatagttgat tttgacgggg
    32281 ttgtatagtt accaatacaa tcaaagcaag agataggata atagctaaaa caattagtat
    32341 ttcaatcata gatctacctc aaaattccca gcaaagtaaa gagcaaacca atcagaatca
    32401 tcaaacccag taaaagtgaa aaagtcttac taatcttttc ccctcgggtt tctttttcct
    32461 tcttgatggg tttttgtttc aactcttcca tgcggccttc aacgtctttg taaaataaat
    32521 cttcctctga catgttagcc tcctaaaaca gtttgcatgg tttcctgata tctcaccaag
    32581 tcaacataat ttgcatgttg gccttgtttg ccaagtgcct gacgcatttg atcaacatct
    32641 gaaagggcca atttaatggt ctcaaccaaa gcagcaactt cactactttc aaatagatgg
    32701 tctggagcga tataaagtct attgtgcacc gtctgattaa agccaagaat caagagattg
    32761 tgctcaaagg cctgacgcac tgcctgtagc aactcattac tgtggtttat atccaagtaa
    32821 atatccgaca gttgatacag ctcctgaatc ttctgtggac tagcgttctg gtaaagggcc
    32881 acattaggat agcaaagcat gtctaagagc ttagaagaca tctctgtcac cgctgcaata
    32941 cggaaagtga catcaggcaa ggctcctgcg attgcttcta cttgctcaat ctgatctgaa
    33001 ttggtcaaga ttaaggcatc tcgtcttagg aaattatcac gtttgaactg gtaatgataa
    33061 cccaagtgca caaactgatc atggtatttc tcgtcagtta actctaaagc gcgctcataa
    33121 gtcgccttat ttggaatgat gatcttctta gtacgcacat tatcactttc caaaatcaac
    33181 tgcatattac ctggaatggc atcatagaga ggttcctgcc ataccaagac atccgagcca
    33241 gatttatctg gatgatggaa ggaaaccaag aaaggagtcg ctagagtatt aaagataagc
    33301 tgactggtat ctatttccaa atcttgcaaa aagaaggtga taaattcaac tttatttgca
    33361 aagtaacgca tggactgacc tggcaaagtc aataagatat cacccgtcac atggttttcc
    33421 agtaaaactt gttgaccatt gacatcttgg taaactgtca taatcggctc gctatctgcg
    33481 ctataagtcg ttgtagcaaa acaagctccg aagcgattgt agtggtcaac ctgacgtact
    33541 cgaccttcta ggtctttcca gtctacctgt ttaaccaagc gagcctgcat tccatcagca
    33601 taatgaatga cagccctctc ctgcgtcaca tcttcaatac aagcagactg attatctcct
    33661 aaaatttccc aaaaatctga aacgggaact tgattaaaat agagaggttt tccatcctcg
    33721 taacctagat aataggtaaa aggagaaagc agaccatcag gcagaaaacc atctgcatcg
    33781 atgaccactc caagttgaga aagaccagta gcgcctagac tttcatgtaa atctcgactt
    33841 tcttgactgt aactatcata aagttcaatc atggagcacc tcctctactg ttttcttcca
    33901 cttttctaaa atttctttgg tcaagaagcc ttctgcaatt tggtaagaat aggcacgcat
    33961 agcttccaaa cgattttctt gatacaattg acaaatctta gcggcataag cttgcttgat
    34021 ttggtcttct acatggtcag atgaacttgg aatcaaataa ccattttgcc catcctctat
    34081 aaaggtctga ttaccataag gcacatcaaa accaattaga ggtagacctg aaccaatagc
    34141 ttccatcaag gtcagaccaa atccttcgct ggtagaagcc gttaagtaga cctcatactg
    34201 gctataaatc tgcgaaagtt ccgcatgccc cttgagttgg atatagtcct ctgcctgatg
    34261 atttgcaata atttctctaa gcagagaatc ttctccacca ctaccataga tatcaaaggt
    34321 tagttccggt aactccttat gagcttcaat cacagctttc acaagccaat caatgtgctt
    34381 ttctttggca agacgtgaag ccgtaatcaa tgaaaatggt ttgcgccctt gacttgaatc
    34441 tgtcaaggaa tcaatactgc ctacaggaat ggtaacaatc tttggctgat gctgagtata
    34501 tttggcaaat tgctcttgta gaacttcatt ttgtctatca gtagacacga taaagaagtc
    34561 aaccttatct gcattggtaa actgatagtc ataatagtta ttccaaagga tatagtcctc
    34621 atttgtagca ttttcactat aatgctccgc atgaacaact accgctagat gtgctgtctg
    34681 tgcttcctca aacacaacct gtccaatacc tgtctcccta tcgagaatga ccaaatcaga
    34741 cttattcaaa ttcaaagatt tcataaaggc acgcacaaaa gcttgctttc catagaaaat
    34801 cttatccttg aaatgataaa cttcttcctt cccttgattc atcaagatat catagactgg
    34861 agtcccgtct tcattataaa aagttcgttg gtataagact gcaacattgt ccttgggagc
    34921 aaaatactcg ctacaataac gcgtataaga aaagtaatcc ttccgaatca ggtttccctt
    34981 aaaaacatac tcggcatgtt gaaccaagtc cttgttctca tcaaccaaat aacaggttac
    35041 aaacttatct tggtcaaaaa agaatacacg taaaaccttg ccattttttt ctctgtgact
    35101 ttcttcacca ccaaagtaag ccaagacatc atccactgtc acgctagtag gtgcaatttt
    35161 gatatctgtg aaatgattat aaagccagat aacctgatta tcatcaaaac caatattggc
    35221 tgttaagtgc tgaatattat cggctaaaat catatctgta aagataaact tagaggacag
    35281 atttaatttc cgaaaaacac cagcacgata ggcttgagcg tattcaacac cgctactagc
    35341 ccaaccaatt cctaaattta tattgtaaat tgtcatattt tctcctttta tggaaaatga
    35401 gtcacgattt caccttttgg agtgacctca accagcccca tcaggagatt acgcaccata
    35461 tccgcatgaa tctgttcttt catagcttca aagcccgcgt aggcttcttg atagtactct
    35521 acgattggat ttttctgact agcagattga ccaccgatag ccatggatag ctgttgtaga
    35581 tagtctacct gctctaccca gttgtcatca atggctttaa gcagtgaaag tcgtaaaaac
    35641 tgttcatata agtcatgttg attaagtaat tctttctttt cagaaagttc tttatcaatc
    35701 acctgcttca taaagctacg aactgcagtt ttgtcagtta catctatata atctggaacc
    35761 tctttaacat gaaaactaat attggtcaca ataaagtgaa acaataattc acgactagca
    35821 tagtgatcag ccgctacctc ttctgtatat ctctcaatga tatccacaac aacatcctct
    35881 aagtcacgag aaccatctat tagacgattt ctctctttat agactatatc ccgttgtata
    35941 ttcatacttt cagcatactc cagagtctga cgacgtgctg aacgtccagc actatcactg
    36001 gcatgctgag ccttttcgac tagtttccgg tatttacgac ctttcaatac ttccggttga
    36061 gtcatatctt gaacctgata gtctttgtac tttttatgca cccaagatgg accaaatttc
    36121 ttgataacat catcctctaa ggatacaaaa aatttactca taccaggatc tccctgacga
    36181 ccagaacggc cacgaatttg taggtcgatc cgctgacttt ccatccgctc agtcccaata
    36241 acaatcaagc ccccaagctc tgcgactcct ttaccaagct tgatatccgt accacgtcct
    36301 gccatagagg tagccactgt cacagccccc atctgacctg actcggagat aatctgagcc
    36361 tcacgcgccg cattattagc atttaggaca ttatgggcaa tcccttcacg aaacaagaga
    36421 gacgaataga gttgagacat ttcaactgag cctacaaaaa cgagtaaagg atttccctta
    36481 gcatggtatt gcttgatgta ctccaaggat gcatacactt tttcaggtaa agtgatatat
    36541 agattatctg gatagtcaat ccgttgtctc ggacgattgg ttggaatgcg tactacagac
    36601 atattgtaag tttcaataaa ctctttttcc gcgaccttac ctgtccctgt cataccagat
    36661 atcttattaa acatcttaaa aagactctga taggtgatcg aggccatagc ccgcgtctca
    36721 ggagataatt tgacatgttc cttggcttca atagcctgat ggagacctcc ttgaagttta
    36781 gtcatttcca ttagacgccc tgttccctta tcaaccagta ccatctcatt tccacgaatg
    36841 atatagtcct tatctttagt aaagagctta tgagctcgaa tcgcataaac caaatgacga
    36901 gcaaaagacg catgctcttc cttgtataaa ttatcaatcc ctaggaaatt ctcagcagac
    36961 ttggccccct tagtagtgag ccaaacctcc tctttctcct ctttaaagat ataatcctct
    37021 ccttcgacca aggttgttac aagtgtatca atgatcgcat agtaattaga ctgaacacga
    37081 ggagaacccg caataatcag aggagtttgt gcactatcaa gcaagatatc atcaatttca
    37141 tcaataatca catagttaaa cggtcgtaaa aacttacctt cttcattcga ggctaggtta
    37201 tcatttagat aatcaaaacc taaattacta ttggttgtgt agatgatatc cgaagcatag
    37261 ataagcttct tttcttcagc tttcatctcc ttctttggat cttccgtaaa tggtacacca
    37321 atggtcaatc ctagaaaacg ataaacttga cccatttcct cggcatcacg ctttgataaa
    37381 tactcattag gagtcacaac catcactcct tctcctgaaa aagcgttcaa atagacaggc
    37441 atggtagctg tcaaggtctt accttccccc gtattcatct cagcaacatt tccatagtgc
    37501 atgacaatag ctcccatgac ttgaacatca taaggaaaca tccctaaaat ccgcttatct
    37561 gcttcacgca ccacagcaaa agcttcaacc aaaatatcgt ctagactttc tccctcggaa
    37621 agacgctgac gaaactctac tgttttagct actaattctt gatccgaaag agaggacatc
    37681 ttgcctttca gggcattaat ctgctttaaa atctttttca ctttcctaag ctggaaatct
    37741 tgacctaaac gtctaaacac ttctgatctc cttgatagaa aaatgataaa aagttaagga
    37801 ctcaaatcca gcacttaaaa gagaaactcg ataagtataa ctatcttctg gataagtaaa
    37861 tatgaaatct ttcacttttt ctaccttttt ttctaaaata tcaccatagc ggtcaaaaaa
    37921 agttatcttg gtataaactc cattttcagg ctgacagtca aaaaccagtg atagttgata
    37981 ctcctgcttt ctttttaata agggaagctg aggttgggtt cgtgcagcct ggtaattgac
    38041 actagaaaac caagtcttta gaatctcacc agatggcaat agaggattat acagacgaac
    38101 acttttgtca gggtaataag atacagttgt tccatacata taagtcccac caacttctcc
    38161 ccaatgaata gactgtctct gtgtaataat catcttttct cccttccaaa accagtctct
    38221 aagaccattc tataaaagtg caaaaaccaa gaaatattgg tatctgtatc atcattgtgt
    38281 cgtccagcag ttcctttaga taaaatcttc gcacctgtat tacacagata agacactaat
    38341 tgttcatagg cttgtggatc catttcttca tctttcatat aggataaacc aaaggttgtc
    38401 tttgaaaaat ttgcttgttt aaaaattttc caaaaacgct gatccaactc cgtcatatct
    38461 tgagaacttg tcccacctgt atgatgaatt aaacaatcaa aagctaagtt agagacaccc
    38521 ggtgcgtcca aacgtccacg actagctata gttcctaaat tagccaaggg cttaccaact
    38581 atgatggcat ggggttcaaa agaagcacca taatagagag ccggaaacgt tcccatagaa
    38641 agacctgata aaatcaaatc cttatgatca aagcctaaat aatcaagata gtgagtgatc
    38701 gtatccttta cttttccctc tagctcatcc gttccgagat aaaaagctcc cccctctaaa
    38761 cgtggatcag aaaataaaat gaagggacat ccaagagttt tcatcataaa gtaaccctcg
    38821 aatccttctg caggtcgata acctgcaaaa tagacagtca aaggcggttt aaaatcacct
    38881 ggatggaaga aatagtttat ttcatcacgc ttggaatcat gtaggatatt tccaccaagt
    38941 acaaacttac caaattgttt tcgactccat cgttggtgaa gattacctag tttgatagtt
    39001 ccacgacctc ttgcttcaac agatatcgag agaaagtagt ctccgtctcg actatccata
    39061 aaaagtgctt gctccaagtc tttttcagat actattactt cttcaaagaa atcatcaaca
    39121 gacccactcc acattttacg gattactaaa cgaaagtcac aattgccttc cttctcatat
    39181 tcaagccaca actcaatagg gagtgttttt tgcaccataa tattataagc ccaataggca
    39241 agctgggcaa aatcttgccc aaactcacct tccaaactga cataatccaa tccttgataa
    39301 gaaatagctc ctgtaaaatt tggattgact tgtatcgtcg gaggaaagag tttatcacca
    39361 tacccaccgc caaaaagaga tttacttaaa tcattgatta gttgttgggg acttaaaaaa
    39421 tcaattgctt gtgcacatcg tttttttaga aaatccacaa cctctctatc atttatttgt
    39481 agattctggt tataaaataa agtataaggt tcaaaatatt ttacatagga aaataagtct
    39541 ctggaatact gaccatcttc tattaaaact gcatgaaaac ggttaatatc ctctttttca
    39601 attatttcac gaagggcttt tgatgagttt gggtaaaaat aataccaact catattttca
    39661 ggtatgtcat agtgattttc ccaattggca agtcctatct gtaaaatatt aagttccttt
    39721 gacattttta acctcctcta tccatttctc taattttcca agaaattgtt gtcctgtgtg
    39781 ctccttaatc ttatcaattg aatatatcaa ggactcattc cactccttca acctatctgt
    39841 gtaataatgt gcagccttag aaaattctgt aacatctgct aacaaataac cattttttaa
    39901 atgttcaaca tagacggttt caactaggtt gatttgagga attcctgcac taatcccagc
    39961 aatctgtgtg tagagatgag gatgtctatt taaatccaca atcaaacgga caaattctag
    40021 tgtttttatc aaatctaact catcattcaa gttaacaaac tgtaagcgta agtcctggtg
    40081 ttgattttct tccagaggat tttctgcatc accataatca atcgcctttc ccagattttc
    40141 ggattgaatg ttttcttgga tgaaagactc aacaatccct tcaacctcat tcatttgctc
    40201 ctgactagca gcaaaggctc caaaaatcac ctcagtatcc ttattttcag cgacaaagga
    40261 caagacttga agcagagctt gattatcaat cccctgctca aaatccagtt gaaaataaat
    40321 gatggattct ttcttagttt ggcttcgtcc caatcgtaat cgggtgtcaa aagatgataa
    40381 atgataacat tgatgcattc gttcaggata caactcctgc aacaatcgta aactatcctc
    40441 tctatccacc aaaatcaaat ccgatttttc aaaagttaca tctaaatccc taaaggtatc
    40501 ttgaggatta cgtccaatga acagactcaa cagtttagga ttagtactag gtaaacgatc
    40561 tagtaccaac tggtcatgat gagaatgaga aggaagcata aaaatatcct gatccttcac
    40621 atacgtttgc agataattct caaaaaattc tgccaccaga tctcccatat tttgataggt
    40681 aagcatttta aagcgataac ccaaaattgg attgacttct acctgtcctc cttcttttaa
    40741 acgctctctg aattgccact ctcccttgag gttcagatat tcttgatagg ctgcttgccc
    40801 atcttcaaaa aagataatgc tcgatacaaa cccacgatca tccacgatat ggtgcatatg
    40861 tatttgacca tttggttcaa aatactgtat atcactgatg aagccttcaa ctccatgttc
    40921 aaccttagca aatttcttcc catttttttg aacgataatc gtaaagggac tataaataaa
    40981 ttcacagtca tcatcccact caatatctct aatgcttaaa acttgggtat ggagattatg
    41041 aaaatcttgc ataacatcaa aaacggaata agtatccatt tctaacacac catgtctata
    41101 taaaaaataa cgtagatgag gctggtaagc taatactaat agacgagaat ctatatcttg
    41161 ctcttgaaag agccgaatct ggtgaaaggt atcatcaaac tctagacgaa aatgagaaaa
    41221 ataccatgga gtgatatctg catgccatgt tctttctgac ccataccaag ctggaataaa
    41281 ataatacata aaagtctcct aaatcaaagg tctataggtc tcatttagcc ttaaagcctt
    41341 gacctcgtct ctaatcgtaa aaatcatgcc cccgaacatc ataaataagc ctggaatcat
    41401 tgccaatcgt aataactttt catcaaacaa aacaaaaagc atgggaccac ctgccataat
    41461 cacattaaag agaccaccta tgactgagaa acgaaggacc aatcgattaa taaatcgact
    41521 agtatccgca cctggataaa taccataaat gtattctcca gattttttca tacggtctgc
    41581 aatctcttct ccattcatcg taacaaaagc aaaaatgata ctaaataaaa ataagaccga
    41641 aatataaaca tagacccaca aaggctttcc aaccataaat tcctttgata aagccgctaa
    41701 ccctgaatga ttagggaaaa taaatcccaa caagatgaac aaataagctg gtacactaag
    41761 aaaactcatc acatacatat aaggcatccc acctgcagga ttcaacatga tttcgagata
    41821 agaatagcgt ttaaatcgat tgtgtaagcc aattttatta acaggaacca aatagcgagc
    41881 tcgatacata agggcaagta aataagaaaa gacaagggtt aataaagcaa gtaacacaat
    41941 aatccctgtt ggaatgtgta ctgtctgaaa tgtttccaaa acatcctgag gaatatttaa
    42001 aaccatactg gataggagga ttacaataga acctccaatc cccatactcg catttaaatc
    42061 tgacaaccaa acaagaaaaa atgttcctgc tatcagcaat attgtattca ttagaacaac
    42121 caatattgca gaataggagg attgtactgg cagtctcaag ctaactgcca aggattgaat
    42181 cacagcaatt agcaaggtca ggtacatttt acggcgatct tgtatttcta tagacgtaga
    42241 tgttaaaccc aaccgtttag aaaaagaaaa catctgccat aaaatcatgg cggacatcca
    42301 aggggataat ccaacagaaa aaattgataa acttcttaga ttcccacctg ttagggcggc
    42361 tgagaaggct agataggctg ttgaacctcc taaaaaatct ttagtattta ggtcaacaaa
    42421 agggagaata atacgacttc ccaatacata gataaacagt agaaatgagg taaatagtcc
    42481 tttttttact gctattgacg aataaatctt agtcataaaa cactcccctc accttcattg
    42541 tttgtgatat ggtaaataac aattctttta tttcaacttt taccatttct ttgttctgca
    42601 tcaaaaaaca actttaatct gaaacaaata tctttatatt cctcagtatc tgttaattga
    42661 tggtattcta aagtttgctt ataatctttt aaaagattga caaatcgaat acgcagaacg
    42721 gagacatcca aaccagccaa gacacaatcc gatattttct tagaaaacac ttcaacaata
    42781 tctcttgccc aggaaagatc aaattccgtt ctcatgatgc ttcctgaacg tcttctatac
    42841 agatagagat tatcgtttat aaagacgatt ttagaggcta aaagataaaa gcgatgcata
    42901 gttgcttcat catcaaagcg gcgaccattt gaaaagtgaa cttcattgaa taattctttt
    42961 ttaatcaact taaatgtcgg caatataaag gccgagctat tgaatttcca atctcctgct
    43021 tgacggttca taatttcttg tatagctaat tcttcgacgc aaaaatcttg ccctgttaca
    43081 taaaaataaa aattcccgtc actttcgtca taattatagt aattccctat aacaacatct
    43141 gcatcctttt cttggacttg ctgataaaga gtttcaatca tattttcttt tacgatatca
    43201 tctgaatcaa caatcgtgat gtactctccc ttagctacac taatccccat atttttagct
    43261 tgtgctgccc cccccttatt ttcttgatgc aatactcgca cacgattatc ttgcatcata
    43321 aaagcatcac aaatttcccc agaattatcc gtagaaccgt catcaactaa aataatttct
    43381 atattttgat aggtttgctt cagaatatgc tcgacacact ccactaaata ttttcccgta
    43441 ttgtatatcg gtaccacaac actaattaat tcactcatta ctctatctct atattcttca
    43501 ttctatccac taaatcatct ggtctctcca cagaaaaaat accgtcatag agtccatcat
    43561 ccatactttt acgtgtgata tcaaaagcga agattttctt gccactttct tgtgcccttg
    43621 taactacatt aaaaacctct ccacctgtat taatatctaa ataaactata gaatcgtcca
    43681 atagccaatc aattctacta tgtaatacat tttgatatac tgttacattc gtatactgtg
    43741 atagagaggt cagctcctca gaacaatcac acggtgcagc caaatgaaaa tgccaatcag
    43801 gtaaccgttg tactaaatac tctaaatgtt ttatatctgc actccatgtc acaagcatca
    43861 cttgtttttt agactgattg cttctttcaa aataatttaa atcggaacgt tgaaaagcaa
    43921 tctctgacca atccaaatct ctataaaccc accataattc acgtagtcta gatatactat
    43981 atgtattcca aggtttatca tgactagcat agtgaacaat tgtaggtgga ttgtcatcta
    44041 gacgttcaca ttcttgagca aggtgataaa tatcaatacc caccatataa ttatatgttt
    44101 tatctaaggc tagccaatta tcctcaaaat aaatatttaa aatactctga tccccaagat
    44161 gaacaacttg attctgctcg gccgctaatt ccaataaact attgacaata gaatgttctt
    44221 tccactttgc aacatccatt agtaacatac cagtattaaa tccagatttt cgtccttcat
    44281 aggcatagac atcatcaaca gcaccaattg aatatccttt gagatctatc tcaaacaaag
    44341 tagctagttc cccagttaca atgatatcgg aatccagata caatacccta tcagattcaa
    44401 ccacttctgt cgcaaaaaat ctaaagtaag aagcataatt tatatgaggt cctgttttat
    44461 agctttcaaa aagttcttta tcaatgtgta cactgcgaat tgtagaattc acaacttcca
    44521 tttttctccc caataattta aaccattcag gagctatatc actgttgaga atataaaaat
    44581 caacatctct attgtgatac aatacagact ttatagtcgt ctctaaagga ataagatagg
    44641 cattatctgc cgctaatact attgattttc tcatactgtt ctctacctca tgtaagatct
    44701 gattgctgca accatttttt tcggaatgga gcttggatag ataccttcat atgaaatctc
    44761 agaaagattt tcagagcaag tattgtcgaa agctatcatt ggttttttgt acttaagcac
    44821 aaactcatat gcatcttcta attttcgatc atgattcaaa tccaaataca aatctgaagc
    44881 tattactatt tgttccaata acattggtaa ggaatttgga tatacggtaa cattaggaaa
    44941 acgcgttaaa gctagtagtt catttgccat atttgtataa gcaacaatat gaaaatgaac
    45001 ttctggcaat tgctccgcca aataatcgat tttctcgaca caccaagaat tcgttaaatt
    45061 aacacattgc aacttaaata tttgtgattt actagggtac ttcacactct ttgaaaacca
    45121 ttcatttaaa ataacagacc aatccatcaa agagtattcc caccaaactt ctcttagacg
    45181 tccaacagaa aattgattcc aaggcttatc ctgagaaata tagtgtaaaa ttagtggcag
    45241 tggttcgagc ggaatatcaa aaatgaattg atgtttaaag gttgccgccc cataatcata
    45301 tcctatttga aaattatatt gatcttcaag ggaactatat tgatctttaa acaacatatt
    45361 caaaattgac tggtctcctt cttccacatt ctcatgttct ttttctgtta agtcaatcaa
    45421 tttttgtcga atagtttcag atccccattt tttgttgtta atcaagagaa caccagcatt
    45481 gaagccgact cctgctccaa agcaagaacg agctgctgcc aaataatttt cacctaagtc
    45541 taattcaaac aaatcggtca aatcaccagt cacaatcaaa tcactatcta gatagagaac
    45601 tttatcttct gttacaaaat ctggaataaa atagcgtgca aatgtcatat gattgatatg
    45661 aggtaattta ttagaccaat tcatttgaaa ctgtgagcca attaacttgc agtcaatcaa
    45721 gtcgcccccc atctcttgta aatatattct tatttgacta aaccattcct gaggaatgtc
    45781 ctgatttagc agataaattt tcaaatgact attgtgtcta cagagtgact tcatcgccgt
    45841 ttcgatttgt cgaatataag cgtaatcacc tgcaaatact acagcgcgtt tggtatttct
    45901 cattttaaat ccttatcatt tattttaaat agtctagttt aatattcgtg caacaatctg
    45961 actgttatag gtttcatcat caataaattc aatatcttgg tcgaaattat gttctgcagt
    46021 atgtttatga gaaaatttaa ccttagtttt agctcccatt ttcatccatt catactctga
    46081 gtcaatatgg cctacatcca aaacttgata gcccatctgg catagattat aactcagaac
    46141 ttttgctgta ggtccaagca tacataaaat caagcgacca ccagcatact tttcaatttc
    46201 ttgttcaagt tcatgaactc tagaaaaggc actatgagaa ggacagataa ttcgcttaat
    46261 agaatttgcc tcatcgaata aatcatttcc gacacctgaa cgagaagtcg caccttcgac
    46321 tatcagtaag tcacggtttt cccaaatgct tttcaatttt tcaaattgag ctttagcttg
    46381 actcttgtct tcaaaatcga tataagggcg agatacaaag gttgagccat accatgaatc
    46441 actgcataac tctctgtaaa aatccatata atgatccatg tgatctttcc aaaatggaat
    46501 cgcccacgat gtaaacctaa aacgatctgt aaaagcatca ggaaggcaca ctactaaatc
    46561 ttctcgactt tcttggccga taatgtccct catgattgaa accaactctt catcataatc
    46621 ctggtaggga attgaatgcc ctgcaagcat attgatttcc ccatctccaa aacgaactaa
    46681 agaagagttg tgttcaataa tataatccaa ggtttcatct atccctttca cctggattat
    46741 atcaagcggt ttttctagca tatccttagt tatcaatttt tgcaaatcag ccaacattcg
    46801 ttcaggatgt tcacttgaat acaacctttg gccattattc ccattttgag atttataaaa
    46861 ggctagtata ggtttagata gatgagccat ttctgcaacg atatcggatg ttgaagtcag
    46921 taggttgata tctaaataag catccatctt ctccttcaac tcgtctagct tatctctaga
    46981 aattgccgga tagagctgaa tattaggata acgattagac aaatcatata attttggccc
    47041 catagctgtc caagcagcaa tttgaaaaac aacatttggc aactgtccag ccaagtaatc
    47101 caattgttcg atatactgag aagccgtaaa cgttaaacaa gttaaacttg gaagttgtcg
    47161 aaaacaggta agatgtccgt ttttcttaaa atctttaatc gtatcaatca taaaggaaac
    47221 tttcccattt tcgaaaacga tttgtcctaa ctctccgtgc tgagtcgatt gaaaagctag
    47281 tagcgttttt tcttgttctt gcaaagattt taaaaagttc tcatctgcac taccatgatt
    47341 gatatccaaa tatagatttg ttgacttttt cagcttatct aagaccggtg gaacaatttg
    47401 tggatgcaat ctcacattat tatatacagc taattttttt aatttatctc ccatatccgt
    47461 ccaagctgcg atatgaaata ccacctcagg tagagctgta actagctctt ctattccttc
    47521 taaatcttgg gaattcgtta aggttaagca agaaaattcc ttatctagag gcgatattag
    47581 ttcaaattct cccatatggt gttgtaaaat ctgactccac tccaaatcat ggaattccca
    47641 ccataaatca cgataacgat tggctgtcaa ggtagtccag ggttttctgt aggtcgtaaa
    47701 atgaatcacc actggtttat cattaaaagc cagatgttcc tgccaattgt tatacaaagc
    47761 cacaatatca tgccctactt gtaaattata agctcgacct agttctaacc aatcatcttg
    47821 caagacctga ttaaaaatcg tttgatcacc attaaaatgc tcgaaacggc cttcttcaac
    47881 ttccttcatt gtaacaatgc tctgttcaat tagtcgttct tttaatttct cttgacgcca
    47941 ttttttattg ttgattaata aaacacctgc attaaatgta attccatctg tatctttaac
    48001 tgctgcgagt gatttttctt ctaaacaaat actaaataat ttctctaaag aagtatttac
    48061 aatcaaatca ctgtctaaat ataaaacctt atcttcttgg atataatctg caataaaata
    48121 tctagcataa gtaatgctac taatgtgatc ttgcttttcc caatcttgaa acacagtttg
    48181 ttcaggtagt ttaacatcga taatctcact acctaacatg cgagctattt ttcgtggttt
    48241 gcgaaaccaa tctggcatga tatcttgatt caaaatataa atcttaacat ctcgattgtg
    48301 gtataaaata gattttatcg ttgtttctaa ctgcctggtg taattgcgat cccctgctag
    48361 tacaattgtt ttgttcattt cattccctta atcaattccc aagtgataga ttgcatctac
    48421 caataacttt ttagtgaaat agccctcttt taacaaatag ctaaaggtct tgatacgatt
    48481 cgtcatttct tgatattctt gtagattcat tttatcaact atctcatgaa cctcttccag
    48541 actatccgcc ataaagccca agccttgatc tactataaat ttagcagttg acaagctact
    48601 tggtacaatg actggaatgc ccgctgttag ataggtactc accttatgag atatattcaa
    48661 ggtatagtat tggttacttt ctccctcatt ttgatgggtt ccccagacaa ggccaaatcc
    48721 accctttgat aattctagca acaattcctc atcttttttc catccttcga tgctgagact
    48781 tctagcacta gaactagctt cccctttatt tgaaaatact ctcaaaggcg tatcttgaga
    48841 ccaattttgt aagtctggaa aacgctctaa acttccagca aaaaaaagtt cttttttaaa
    48901 agcaggggtg tataaggata aatcatgagg atgatcccac atcccttgaa caagaatctt
    48961 cttagtcgtc aatccttctt ccatcaggcg tgttttcatt ctctctgacg gcactatcaa
    49021 aacatctgat agattataca tatacagata atctttcatg agataatagt tactatcaaa
    49081 catgagggga acaacatcat ggataaagca aataattttc acctgcatat cctttagctt
    49141 atcaaacaag agacgatcaa attcaaaacc attccaggtt ggagactgaa agactaaaat
    49201 atccccaata gagatactgg ccataatacc atccagacgc ttattcattt cagaaggact
    49261 atctgaagca atgttgtaaa aataaatacc aacctctcta aatcccagtt gactagctat
    49321 cttttgaaca gcattttgag ctaagataac cgtactatca ccagccatgc cgtataaatt
    49381 tgttaaatgt agtttcatat tacgctatct cattttttat tactatctac ggaagtaaag
    49441 acaatttttc catcattctt ctgtaaatct ctgtgaactg catattttgt tcttctaatt
    49501 ttgctatcac tctttgtaat ctatttttat aaatcaaaat atgattggtc aagtcatagt
    49561 ctgaacttgc taaaatagct atcttttctt ccctagcccc aatttcatca tacatacgct
    49621 tttcactcca tgtattcgat aaagtatcag ataaaccaac acggtaccag taaacacaac
    49681 gattcaaata gactatcctc gaagctctta gaagtacctt ccatgtccag taagtatcct
    49741 ctgcaatttt tcctatagga aatggtaaat cttgtagtaa ctctctcttg aataacttca
    49801 agacagctac agtccagttc ccatttctga cttcttcgac accttcccta tccataattg
    49861 ctttaccttc tatcacttct agagaatcat ctggatccgt aacataagtc atatacacat
    49921 agcgtgtttc atcataagaa ttataacgcc cgatactaat atctgcgttt tcctttttca
    49981 aagcaccata taatcggtct aaagcatcat gttccaacca atcatcagag tctacaaaag
    50041 taatgtacgc cccccccgaa cattcaatac ctaggttacg agctgatgaa agaccgccgt
    50101 ttgctttctc aaaatatttg aaacgagaat ctttctctac aaattcttca catattttgg
    50161 atgaatgatc tggagagcca tcattgatta ataaacactc aaaattttga tacgtctgat
    50221 tctgaatgct atccaaacac attcgcaaat aattctcaac gttgtagatt ggaactacaa
    50281 tactaattag ttcgtctgcc ataaacttat tctcctataa attgtctaat agcctctacc
    50341 attttgtttg gttcggttga agaaaatata ttagtttgat tgcctatatc atgactagta
    50401 ttttcaaagg taaaaattgg tttagatagt tgttgaacaa cggatacaat attatccact
    50461 tctttataat gattaatatc taaataaaaa tctaaattat ccaaaatttt tcgataatca
    50521 aatggagaaa aacaaggata aatcgtaaca ttgctatatc ttaataaagc aacgacacta
    50581 gacgcaaaat atgtatgtgc tagtatagaa aaatgtacct ctggtaaatt ttctatcaaa
    50641 tattctacat gctccatctc acaactagct gtaaaaattg ctgtatgagc tttaggactg
    50701 tatacaagtt cttcgaaact acgactaata atgtcttttc tcaataaaag atcagaccat
    50761 tctaacagat tataaaacca ccaaacttct ctaaagcgat tattggaaat tatttcccaa
    50821 ggttttaccc cagtataatg tataacacta ggtaaatctc catttttcaa ctcagaaatc
    50881 tcataccatt tatgatttcc ttctatgtgt gcgacgctat ccatccccac cataaaatta
    50941 aaatttcggt ctaatctttt ccatctatca tggaataaca tatttaaaat tccttgatct
    51001 ccatatgctg tttcatgata ttgattggtc agttctaaca gtttcgaaca agcatcttca
    51061 tctctccaag tatctacatt aactaataac attccggagt taaaattggt agaaggaaca
    51121 tcaccaaaag aatcttctac tgctgccaag gcataaccat ctagttctat atcaaataaa
    51181 tagtctaaac ttcctgtaac aatgatgtca gaatctaggt ataaagcacg actttctttg
    51241 acaaaattag gtataaaata acgaaagaaa gtggcataac ttaaattctt taacggtaaa
    51301 tgaaactttt taagaacatg atctacaatc tttacattaa cgatttcaga ttgtatagtc
    51361 ttcaatcgct tattcatcat caaaaaccac tctgacgcaa tatcatcatt aaatacataa
    51421 aattttaaac aattattata acaacaaata gatttaattg cagtttctaa tttatctaca
    51481 taatcattat ctgcattaaa aactatagat tttgtattca ttaacataat ttccttataa
    51541 taaatttcgt atcaaacagc tataatatag aatcattttc acctaaaaag ataattaatc
    51601 acaccctaat attgtactga ccccaaaaag ttagattttt tctgtctaac ttttggggtg
    51661 cagttcatat taaatatctt taggtctatt tatattttat aaagcactct gatgtttgaa
    51721 caactttcat atatgatgaa cggagaaatt ttataaaaaa taatccaact cttcaatctg
    51781 atcactaacc gtcaaaatca gagcatctcc tactaaatga tttttcttca tttgcttatt
    51841 tctctcaatt tttcaatcat tgcttgaact tggtcaacag catatgcctc ctgacctact
    51901 tcataggttt tagtattttc aaaggataag ataggcttgc caagattagc aaattgatcg
    51961 agaatttctt ctgtcttttc gccatgatta atatctaaaa gtacttgact ggtttctacc
    52021 aattcattat cgacatctac caaatagtga attccgttaa atatagtcac gtttggataa
    52081 attgtcatct gagccaatcg atcactaact attactctag ctgctatctt aaactgaata
    52141 tcaggcaagg attgaaccaa tgtctcaatt tgttcaatat ggtctgaggc agtatagatt
    52201 agacaagtga aaggttcctt tattggatag atgtgagatc tttgtaatgg atgtaaatga
    52261 tggttttgtc ccaattctgt ccattcaagc ccatgatagt accaccaaac ttcacgatag
    52321 gtttgggccg ccaaatcttt ccacggtttc cgatgagaaa gatagtgaat aatagcagga
    52381 taatcctgac cctcaggcaa ttgataatca gcaaactgtt tatgaatgac aatatgatta
    52441 taatcaaagt ccaattccaa ccatttatgt tcaaaaagca tattcaagat gctctgatct
    52501 gcctgatcca ccttatcatg ccattcattg gttacatcaa ttaatttttg ggtcatattc
    52561 tcttttttcc aaaaagcatt gtttaccaag agaacaccgg cattaaagat ttcttgacca
    52621 aaataagctc tgcccccaaa atctctaaca gcagccaaag gataatcttg taagtctgta
    52681 gcaaacaagt catccagatt tttcgttaca actagatcac agtccaagta gagggccttg
    52741 tcttcttgca cgaaatcagc tatgaaatag cgtaaaaaga ctgtgtaact aatatccgat
    52801 ttataacatg aaatttgctc agaagttacc cgacaattaa taatttctga gtcaaacttc
    52861 tctaagcgct tatttaattg cttaatccat tcatttggaa aatcgctatg aatcagataa
    52921 aaacgaatcg aacgattatg ataacaaata gacttgattg tcgttaaaac ttggtctaca
    52981 tagccatagt ttgctgcgag gacaatggct ttcttttcac tttcctcttg tctcgatagc
    53041 tgatttaaaa gcctttgttt catttcaaac tctttatacg ttgctgtgtc agataaacca
    53101 ctagcttgac cgttggcgag actgacttcc aacatctgac gataaactgc caagtgtttc
    53161 tctagaggat aacccatatt agctagtagc gtaatacgtt cagacatagc atcaactaaa
    53221 gcgtgcatcc acttttctgt ccaaactctt gataaactac cttttctaat ccgataagca
    53281 taaagacttt tatttaaata aattaccttt tctgataata aatatacctt ttgattgagg
    53341 taaccatctt ctcctaattt acctatgtca aagcgcaact gctcaaacaa tcttgcctta
    53401 tagagtttac cccaagcaga tatcaaagca aaactcttca tttcttgagt ttcatacaag
    53461 ttctcaaaga tagaaacatt atcatatact ttctcataat aggagtctcc caatatatga
    53521 aagtagaaca ttccttcact ttcgttgaaa gaataataat taccaactgc aatatcagcc
    53581 tgatactcta ctattttttt atatagagtt tctacataat cttgctcaat ccaatcatcc
    53641 gagtccacaa aggtcacata atttccggac atattattca gaccggtgtt tcgtgcggca
    53701 gaaagaccag cattttcttg ttctatatag agaattcggt gatccatttc tgaaaattct
    53761 ttacaaattt cacctgaagc atccgtagaa ccatcattaa cgacaacaat ctcaatattt
    53821 ttatatgttt gagtaataat actatctagg cacttcctca gatagttttc cacattgtat
    53881 actggtacaa tgactgttat tttatcatcc actagcaatt ttctccttga tttatgtgcg
    53941 cgagttagtt tagcctaact ttacaggttg tcttactctt cttcatcacg tttacggcgt
    54001 ttcgcaacca atccaatacc tgtaacagct gctagaactc caagtaacac agatccaatt
    54061 gacgactcag tacctgtatt aggcaattct ttttgggatt tacctgtcga tccagaagta
    54121 tttccaactt gtgagttcga atggtttgct gaatttgaaa ctgatgtact tgctgaagct
    54181 gacgcacttg ttgatgctga agctgaagca ctggtgcttg ctgaggccga ggcactggtt
    54241 gaggccgacg cacttgtcga cgctgaggct gacgcactgg tacttgctga ggctgacgca
    54301 ctggtacttg ctgaagccga cgcacttgtc gacgctgagg ctgacgcact ggtacttgct
    54361 gaagctgagg cgcttgtcga tgctgaggct gacgcactgg ttgatgcaga ttcagaagct
    54421 gatgtgcttg ctgaggctga cgcactcgtt gatgctgact cagacgcact cgttgacgct
    54481 gaagccgatg cacttgttga cgctgaggct gaggcgctag tacttgctga agcgga
//
LOCUS       DAVFER010000011        54397 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1105170250
            SAMEA2167659-rid19724873.denovo.011, whole genome shotgun sequence.
ACCESSION   DAVFER010000011 DAVFER010000000
VERSION     DAVFER010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2167659
            Sequence Read Archive: ERR388902
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 54397)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 54397)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928716.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928716.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 04:07:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,118
            CDSs (total)                      :: 2,073
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 120
            CDSs (without protein)            :: 120
            Pseudo Genes (ambiguous residues) :: 0 of 120
            Pseudo Genes (frameshifted)       :: 67 of 120
            Pseudo Genes (incomplete)         :: 47 of 120
            Pseudo Genes (internal stop)      :: 34 of 120
            Pseudo Genes (multiple problems)  :: 23 of 120
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..54397
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2167659-rid19724873.denovo.011"
                     /strain="1105170250"
                     /db_xref="taxon:1313"
     gene            987..1439
                     /locus_tag="VU534_000650"
     CDS             987..1439
                     /locus_tag="VU534_000650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HEU1513280.1"
                     /translation="MIITKISRLGTYVGVNPHFATLIDFLEKTGLENLTEGSIAIDGN
                     RLFGNCFTYLADGQAGAFFETHQKYLDIHLVLENEEAMAVTSPENVSVTQEYDEEKDI
                     ELYTGKVEQLVHLRAGECLITFPEDLHQPKVRINDEPVKKVVFKVAIS"
     gene            1458..2795
                     /locus_tag="VU534_000651"
     CDS             1458..2795
                     /locus_tag="VU534_000651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HEU1513281.1"
                     /translation="MKKMRKFLCLAGIALAAVALVACSGKKEATTSTEPPTELSGEIT
                     MWHSFTQGPRLESIQKSADAFMQKHPKTKIKIETFSWNDFYTKWTTGLANGNVPDIST
                     ALPNQVMEMVNSDALVPLNDSIKRIGQDKFNETALNEAKIGDDYYSVPLYSHAQVMWV
                     RTDLLKEHNIEVPKTWDQLYEASKKLKEAGVYGLSVPFGTNDLMATRFLNFYVRSGGG
                     SLLTKDLKADLTSQLAQDGIKYWVKLYKEISPQDSLNFNVLQQATLFYQGKTAFDFNS
                     GFHIGGINANSPQLIDSIDAYPIPKIKESDKDQGIETSNIPMVVWKNSKHPEVAKAFL
                     EALYNEEDYVKFLDSTPVGMLPTIKGISDSAAYKENETRKKFKHAEEVITEAVKKGTA
                     IGYENGPSVQAGMLTNQHIIEQMFQDIITNGTDPMKAAKEAEKQLNDLFEAVQ"
     gene            2874..3758
                     /locus_tag="VU534_000652"
     CDS             2874..3758
                     /locus_tag="VU534_000652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEU1513282.1"
                     /translation="MVKERNLTRWIFVLPAMIIVGLLFVYPFFSSIFYSFTNKHLIMP
                     NYKFVGLANYKAVLSDPNFFNAFFNSIKWTVFSLVGQVLVGFVLALALHRVRHFKKLY
                     RTLLIVPWAFPTIVIAFSWQWILNGVYGYLPNLIVKLGLMEHTPAFLTDSTWAFLCLV
                     FINIWFGAPMIMVNVLSALQTVPEEQFEAAKIDGASSWQVFKFIVFPHIKVVVGLLVV
                     LRTVWIFNNFDIIYLITGGGPANATTTLPIFAYNLGWGTKLLGRASAVTVLLFIFLVA
                     ICFIYFAIISKWEKEGRK"
     gene            3758..4591
                     /locus_tag="VU534_000653"
     CDS             3758..4591
                     /locus_tag="VU534_000653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEU1513283.1"
                     /translation="MKKKSSIYLDILSHVLLVGATIVAVFPLVWIIISSVKGKGELTQ
                     YPTRFWPEQFTLDYFTHVINDLHFIDNIRNSLIIALATTLIAIIISAMAAYGIVRFFP
                     KLGAIMSRLLVITYIFPPILLAIPYSIAIAKVGLTNSLFGLMMVYLSFSVPYAVWLLV
                     GFFQTVPIGIEEAARIDGANKFVTFYKVVLPIVAPGIVATAIYTFINAWNEFLYALIL
                     INNTGKMTVAVALRSLNGSEILDWGDMMAASVIVVLPSIIFFSIIQNKIASGLSEGSV
                     K"
     gene            4609..6702
                     /gene="nanB"
                     /locus_tag="VU534_000654"
     CDS             4609..6702
                     /gene="nanB"
                     /locus_tag="VU534_000654"
                     /EC_number="3.2.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="neuraminidase NanB"
                     /protein_id="HEU1513284.1"
                     /translation="MNKRGLYSKLGISVVGISLLMGVPTLIHANELNYGQLSISPIFQ
                     GGSYQLNNKSIDISSLLLDKLSGESQTVVMKFKADKPNSLQALFGLSNSKAGFKNNYF
                     SIFMRDSGEIGVEIRDAQKGINYLFSRPASLWGKHKGQAVENTLVFVSDSKDKTYTMY
                     VNGIEVFSETVDTFLPISNINGIDKATLGAVNREGKEHYLAKGSIDEISLFNKAISDQ
                     EVSTIPLSNPFQLIFQSGDSTQANYFRIPTLYTLSSGRVLSSIDARYGGTHDSKSKIN
                     IATSYSDDNGKTWSEPIFAMKFNDYEEQLVYWPRDNKLKNSQISGSASFIDSSIVEDK
                     KSGKTILLADVMPAGIGNNNANKADSGFKEINGHYYLKLKKNGDNDFRYTVRENGVVY
                     NETTNKPTNYTINDKYEVLEGGKSLTVEQYSVDFDSGSLRERHNGKQVPMNVFYKDSL
                     FKVTPTNYIAMTTSQNRGESWEQFKLLPPFLGEKHNGTYLCPGQGLALKSSNRLIFAT
                     YTSGELTYLISDDSGQTWKKSSASIPFKNATAEAQMVELRDGVIRTFFRTTTGKIAYM
                     TSRDSGETWSKVSYIDGIQQTSYGTQVSAIKYSQLIDGKEAVILSTPNSRSGRKGGQL
                     VVGLVNKEDDSIDWKYHYDIDLPSYGYAYSAITELPNHHIGVLFEKYDSWSRNELHLS
                     NVVQYIDLEINDLTK"
     gene            6714..7817
                     /locus_tag="VU534_000655"
     CDS             6714..7817
                     /locus_tag="VU534_000655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEU1513285.1"
                     /translation="MVKYGVVGTGYFGAELARYMQKNDGAEITLLYDPDNAEAIAEEL
                     GAKVASSLDELVSSDEVDCVIVATPNNLHKEPVIKAAQHGKNVFCEKPIALSYQDCRE
                     MVDACKENNVTFMAGHIMNFFNGVHHAKELINQGVIGDVLYCHTARNGWEEQQPSVSW
                     KKIREKSGGHLYHHIHELDCVQFLMGGMPETVTMTGGNVAHEGEHFGDEDDMIFVNME
                     FSNKRFALLEWGSAYRWGEHYVLIQGSKGAIRLDLFNCKGTLKLDGQESYFLIHESQE
                     EDDDRTRIYHSTEMDGAIAYGKPGKRTPLWLSSVIDKEMRYLHEIMEGAPVSEEFAKL
                     LTGEAALEAIATADACTQSMFEDRKVKLSEIVK"
     gene            7991..8689
                     /locus_tag="VU534_000656"
     CDS             7991..8689
                     /locus_tag="VU534_000656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HEU1513286.1"
                     /translation="MPQISKEALIEQIKDGIIVSCQALPHEPLYTEAGGVIPLLVKAA
                     EQGGAVGIRANSVRDIKEIKEVTKLPIIGIIKRDYPPQEPFITATMKEVDELAELDIE
                     VIALDCTKRERYDGLEIQEFIRQVKEKYPNQLLMADTSIFEEGLAAVEAGIDFVGTTL
                     SGYTSYSPKVDGPDFELIKKLCDAGVDVIAEGKIHTPEQAKQILEYGVRGIVVGGAIT
                     RPKEITERFVASLK"
     gene            8708..10225
                     /locus_tag="VU534_000657"
     CDS             8708..10225
                     /locus_tag="VU534_000657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000477452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEU1513287.1"
                     /translation="MFKVLQKVGKAFMLPIAILPAAGLLLGIGGALSNPTTIATYPIL
                     DNSIFQSIFQVMSSAGEVVFSNLSLLLCVGLCIGLAKRDKGTAALAGVTGYLVMTATI
                     KALVKLFMAEGSAIDTGVIGALVVGIVAVYLHNRYNNIQLPSALGFFGGSRFVPIVTS
                     FSSILIGFVFFVIWPPFQQLLVSTGGYISQAGPIGTFLYGFLMRLSGAVGLHHIIYPM
                     FWYTELGGVETVAGQTVVGAQKIFFAQLADLAHSGLFTEGTRFFAGRFSTMMFGLPAA
                     CLAMYHSVPKNRRKKYAGLFFGVALTSFITGITEPIEFMFLFVSPVLYVVHAFLDGVS
                     FFIADVLNISIGNTFSGGVIDFTLFGILQGNAKTNWVLQIPFGLIWSVLYYIIFRWFI
                     TQFNVLTPGRGEEVDSKEISESADSTSNTADYLKQDSLQIIRALGGSNNIEDVDACVT
                     RLRVAVKEVNQVDKALLKQIGAVDVLEVKGGIQAIYGAKAILYKNSINEILGVDD"
     gene            10350..11678
                     /locus_tag="VU534_000658"
     CDS             10350..11678
                     /locus_tag="VU534_000658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HEU1513288.1"
                     /translation="MKFRKLACTVLAGAAVLGLAACGNSGGSKDAAKSGGDGAKTEIT
                     WWAFPVFTQEKTGDGVGTYEKSIIEAFEKANPDIKVKLETIDFKSGPEKITTAIEAGT
                     APDVLFDAPGRIIQYGKNGKLAELNDLFTDEFVKDVNNENIVQASKAGDKAYMYPISS
                     APFYMAMNKKMLEDAGVANLVKEGWTTDDFEKVLKALKDKGYTPGSLFSSGQGGDQGT
                     RAFISNLYSGSVTDEKVSKYTTDDPKFVKGLEKATSWIKDNLINNGSQFDGGADIQNF
                     ANGQTSYTILWAPAQNGIQAKLLEASKVEVVEVPFPSDEGKPALEYLVNGFAVFNNKD
                     DKKVAASKKFIQFIADDKEWGPKDVVRTGAFPVRTSFGKLYEDKRMETISGWTQYYSP
                     YYNTIDGFAEMRTLWFPMLQSVSNGDEKPADALKAFTEKANETIKKAMKQ"
     gene            11930..12796
                     /locus_tag="VU534_000659"
     CDS             11930..12796
                     /locus_tag="VU534_000659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEU1513289.1"
                     /translation="MRETVISYAFLAPVLFFFVIFVLAPMVMGFITSFFNYSMTKFEF
                     VGLDNYIRMFKDPVFTKSLINTVILVIGSVPVVVLFSLFVASQTYHQNVIARSFYRFV
                     FFLPVVTGSVAVTVVWKWIYDPLSGILNFVLKSSHIISQNISWLGDKNWALMAIMIIL
                     LTTSVGQPIILYIAAMGNIDNSLVEAARVDGATEFQVFWKIKWPSLLPTTLYIAIITT
                     INSFQCFALIQLLTSGGPNYSTSTLMYYLYEKAFQLTEYGYANTIGVFLAVMIAIVSF
                     VQFKVLGNDVEY"
     gene            12812..13651
                     /locus_tag="VU534_000660"
     CDS             12812..13651
                     /locus_tag="VU534_000660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEU1513290.1"
                     /translation="MQSTEKKPLTAFTVISTIILLLLTVLFIFPFYWILTGAFKSQPD
                     TIVIPPQWFPKMPTMENFQQLMVQNPALQWMWNSVFISLVTMFLVCATSSLAGYVLAK
                     KRFYGQRILFAIFIAAMALPKQVVLVPLVRIVNFMGIHDTLWAVILPLIGWPFGVFLM
                     KQFSENIPTELLESAKIDGCGEIRTFWSVAFPIVKPGFAALAIFTFINTWNDYFMQLV
                     MLTSRNNLTISLGVATMQAEMATNYGLIMAGAALAAVPIVTVFLVFQKSFTQGITMGA
                     VKG"
     gene            13923..14375
                     /locus_tag="VU534_000661"
     CDS             13923..14375
                     /locus_tag="VU534_000661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000575445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HEU1513291.1"
                     /translation="MIFDDLKNITFYKGIHPNLDKAIDYLYQHRKDSFELGKYDIDGD
                     KVFLVVQENVLNQAENDQFEYHKNYADLHLLVEGHEYSSYGSRIKDEAVAFDEASDIG
                     FVHCHEHYPLLLGYHNFAIFFPGEPHQPNGYAGMEEKVRKYLFKILID"
     gene            14472..14816
                     /locus_tag="VU534_000662"
     CDS             14472..14816
                     /locus_tag="VU534_000662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000254916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1513292.1"
                     /translation="MVSSKYAARASFLDGQGITVDEMAWIIRGIVNALIGRYIKLGTY
                     AAKYGISMARSILSRVAATAAARVGLLTKISGWILRVAVNVADVYGNFANNIAAAWDA
                     YDKIPNNGRINF"
     gene            15093..15737
                     /locus_tag="VU534_000663"
     CDS             15093..15737
                     /locus_tag="VU534_000663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000057467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HEU1513293.1"
                     /translation="MAQKGVSLIKAAFDTDNFLMRFSEKVLDIVTANLLFVVSCLPIV
                     TIGVAKISLYETMFEVKKSRRVPVFKIYLRSFKQNLKLGLQLGLMELGIVFLTLSDLY
                     LFWGQTALPFQLLKAICLGILIFLTIVMLASYPIAARYDLSWKEILQKGLMLASFNFP
                     WFFLMLAILVLIVMVLYLSAFSLLLGGSVFLLFGFGLLVFIQTGLMEKIFAKYQ"
     gene            15906..16823
                     /locus_tag="VU534_000664"
     CDS             15906..16823
                     /locus_tag="VU534_000664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="HEU1513294.1"
                     /translation="MSDLKKYEGVIPAFYACYDDQGEVSPERTRALVQYFIDKGVQGL
                     YVNGSSGECIYQSVEDRKLILEEVMAVAKGKLTIIAHVACNNTKDSMELARHAESLGV
                     DAIATIPPIYFRLPEYSVAKYWNDISSAAPNTDYVIYNIPQLAGVALTPSLYTEMLKN
                     PRVIGVKNSSMPVQDIQTFVSLGGEDHIVFNGPDEQFLGGRLMGARAGIGGTYGAMPE
                     LFLKLNQLIADKDLETARELQYAINAIIGKLTSAHGNMYGVIKEVLKINEGLNIGSVR
                     SPLTPVTEEDRPVVEAAAALIRETKERFL"
     gene            16841..17725
                     /locus_tag="VU534_000665"
     CDS             16841..17725
                     /locus_tag="VU534_000665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEU1513295.1"
                     /translation="MTYYVAIDIGGTNIKYGLVDQEGQLLESHEMPTEAHKGGPHILQ
                     KTKDIVASYLEKGPVAGVAISSAGMVDPDKGEIFYAGPQIPNYAGTQFKKEIEESFTI
                     PCEIENDVNCAGLAEAVSGSGKGASVTLCLTIGTGIGGCLIMDRKVFHGFSNSACEVG
                     YMHMQDGAFQDLASTTALVKYVAEAHGEDVDQWNGRRIFKEATEGNKICMEGIDRMVD
                     YLGKGLANICYVANPEVVILGGGIMGQEAILKPKIRTALKEALVPSLAEKTRLEFAHH
                     QNTAGMLGAYYHFKTKQS"
     gene            complement(17741..18592)
                     /locus_tag="VU534_000666"
     CDS             complement(17741..18592)
                     /locus_tag="VU534_000666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HEU1513296.1"
                     /translation="MDKPDIATIIDSHFEEMTDLEQEIARYFLQAETITDDLSSQQVT
                     QKLHISQAALTRFAKKCGFTGYREFIFQYQHQAENQANQVSKHSPLTKRVLRSYSNMR
                     EQTQDLIDEIQLERIAQLIEDAERIYFFGTGSSGLVAREMKLRFMRLGVVCEALTDQD
                     GFAWTTSIMDENCLVLGFSLSGSTPSILDSLLDAKEMGAKTVLFTSVPNKDSQTYTET
                     VLVATHSQPSYIQRISAQLPMLFFIDLIYAYFLEINRESKEKIFNSYWENKKLNGYRR
                     QKRVRKS"
     gene            18792..20849
                     /gene="pbp2b"
                     /locus_tag="VU534_000667"
     CDS             18792..20849
                     /gene="pbp2b"
                     /locus_tag="VU534_000667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2B"
                     /protein_id="HEU1513297.1"
                     /translation="MRLICMRKFNSHSIPIRLNLLFSIVILLFMTIIGRLLYMQVLNK
                     DFYEKKLASASQTKITSSSARGEIYDASGKPLVENTLKQVVSFTRSNKMTATDLKETA
                     KKLLTYVSISSPNLTERQLADYYLADPEIYKKIVEALPSEKRLDSDGNRLSESELYNN
                     AVDSVQTSQLNYTEDEKKEIYLFSQLNAVGNFATGTIATDPLNDSQVAVIASISKEMP
                     GISISTSWDRKVLETSLSSIVGSVSSEKAGLPAEEAEAYLKKGYSLNDRVGTSYLEKQ
                     YEETLQGKRSVKEIHLDKYGNMESVDTIEEGSKGNNIKLTIDLAFQDSVDALLKSYFN
                     SELENGGAKYSEGVYAVALNPKTGAVLSMSGIKHDLKTGELTPDSLGTVTNVFVPGSV
                     VKAATISSGWENGVLSGNQTLTDQSIVFQGSAPINSWYTQAYGSFPITAVQALEYSSN
                     TYMVQTALGLMGQTYQPNMFVGTSNLESAMEKLRSTFGEYGLGTATGIDLPDESTGFV
                     PKEYSFANYITNAFGQFDNYTPMQLAQYVATIANNGVRVAPRIVEGIYGNNDKGGLGD
                     LIQQLQPTEMNKVNISDSDMSILHQGFYQVAHGTSGLTTGRAFSNGALVSISGKTGTA
                     ESYVADGQQATNTNAVAYAPSDNPQIAVAVVFPHNTNLTNGVGPSIARDIINLYQKYH
                     PMN"
     gene            20860..21456
                     /gene="recR"
                     /locus_tag="VU534_000668"
     CDS             20860..21456
                     /gene="recR"
                     /locus_tag="VU534_000668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein RecR"
                     /protein_id="HEU1513298.1"
                     /translation="MLYPTPIAKLIDSYSKLPGIGIKTATRLAFYTIGMSADDVNEFA
                     KNLLSAKRELTYCSICGRLTDDDPCSICTDPTRDQTTILVLEDSRDVAAMENIQEYHG
                     LYHVLHGLISPMNGISPDDINLKSLMTRLMDSEVSEVIVATNATADGEATSMYLSRLL
                     KPAGIKVTRLARGLAVGADIEYADEVTLLRAIENRTEL"
     gene            21632..22675
                     /locus_tag="VU534_000669"
     CDS             21632..22675
                     /locus_tag="VU534_000669"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HEU1513299.1"
                     /translation="MKQTIILLYGGRSAEREVSVLSAESVMRAVDYDRFTVKTFFISQ
                     SGDFIKTQEFSHAPGQEDRLMTNETIDWDKKVAPSAIYEEGAVVFPVLHGPMGEDGSV
                     QGFLEVLKMPYVGCNILSSSLAMDKITTKRVLESAGIAQVPYVAIVEGDDVTAKIAEV
                     EEKLAYPVFTKPSNMGSSVGISKSENQEELRQALKLAFRYDSRVLVEQGVNAREIEVG
                     LLGNYDVKSTLPGEVVKDVAFYDYDAKYIDNNITMDIPAKISDDVVAVMRQNAETAFR
                     AIGGLGLSRCDFFYTDKGEIFLNELNTMPGFTQWSMYPLLWDNMGISYPKLIERLVDL
                     AKESFDKREAHLI"
     gene            22759..24132
                     /locus_tag="VU534_000670"
     CDS             22759..24132
                     /locus_tag="VU534_000670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000778684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HEU1513300.1"
                     /translation="MKLTIHEIAQVVGAKNDISIFEDTQLEKAEFDSRLIGTGDLFVP
                     LKGARDGHDFIETAFENGAAVTLSEKEVSNHPYILVDDVLTAFQSLASYYLEKTTVDV
                     FAVTGSNGKTTTKDMLAHLLSTRYKTYKTQGNYNNEIGLPYTVLHMPEGTEKLVLEMG
                     QDHLGDIHLLSELARPKTAIVTLVGEAHLAFFKDRSEIAKGKMQIADGMASGSLLLAP
                     ADPIVEDYLPTDKKVVRFGQGAELEITDLVERKDSLTFKANFLEQALDLPVTGKYNAT
                     NAMIASYVALQEGVSEEQIRLAFQDLELTRNRTEWKKAANGADILSDVYNANPTAMKL
                     ILETFSAIPANEGGKKIAVLADMKELGDQSVQLHNQMILSLSPDVLDTVIFYGENIAE
                     LAQLASQMFPIGHVYYFKKTEDQDQFEDLVKQVKESLGAHDQILLKGSNSMNLAKLVE
                     SLENEDK"
     gene            24119..24730
                     /locus_tag="VU534_000671"
     CDS             24119..24730
                     /locus_tag="VU534_000671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEU1513301.1"
                     /translation="MKTSDFVKYLQRMIAITDTGLTFTKDPFDRERYEDLRSLLSEML
                     NQASDLDSEEVAEVLKPTSAYATPLMDVRAWIVEDEKICLVRGQGEDSWALPGGFGEV
                     GYSPTENILKEIEEETGFKAKVERLLAVFDTNRFQLQSKQYTKFVFGCKLLDGQFQEN
                     QEIADLQFFAIDQLPNLSEKRITKEQIELLWQVYQGHRGQYLD"
     gene            24821..25525
                     /locus_tag="VU534_000672"
     CDS             24821..25525
                     /locus_tag="VU534_000672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001055242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR02206 family membrane protein"
                     /protein_id="HEU1513302.1"
                     /translation="MNLWDIFFTTQATEPPKFDLFWYVSLFTLLALTFYTAHRYREKK
                     VYQRFFQILQTVQLILLYGWYWVNHMPLSESLPFYHCRMAMFVVLLLPGQSKYKQYFA
                     LLGTFGTLAAFVYPVPDAYPFPHITILSFIFGHLALLGNSLVYLLRQYNARLLDVKGI
                     FLMTFALNALIFVVNLVTGGDYGFLTKPPLVGDHGLVANYLLVSIVLVATISLTKKIL
                     EFFLAQEAEKMIAKEA"
     gene            25744..27117
                     /gene="ftsA"
                     /locus_tag="VU534_000673"
     CDS             25744..27117
                     /gene="ftsA"
                     /locus_tag="VU534_000673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000090410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HEU1513303.1"
                     /translation="MAREGFFTGLDIGTSSVKVLVAEQRNGELNVIGVSNAKSKGVKD
                     GIIVDIDAAATAIKSAISQAEEKAGISIKSVNVGLPGNLLQVEPTQGMIPVTSDTKEI
                     TDQDVENVVKSALTKSMTPDREVITFIPEEFIVDGFQGIRDPRGMMGVRLEMRGLLYT
                     GPRTILHNLRKTVERAGVQVENVIISPLAMVQSVLNEGEREFGATVIDMGAGQTTVAT
                     IRNQELQFTHILQEGGDYVTKDISKVLKTSRKLAEGLKLNYGEAYPPLASKETFQVEV
                     IGEVEAVEVTEAYLSEIISARIKHILEQIKQELDRRRLLDLPGGIVLIGGNAILPGMV
                     ELAQEVFGVRVKLYVPNQVGIRNPAFAHVISLSEFAGQLTEVNLLAQGAIKGENDLSH
                     QPISFGGMLQKTAQFVQSTPVQPAPAPEVEPVAPTEPMADFQQASQNKPKLADRFRGL
                     IGSMFDE"
     gene            27134..28393
                     /gene="ftsZ"
                     /locus_tag="VU534_000674"
     CDS             27134..28393
                     /gene="ftsZ"
                     /locus_tag="VU534_000674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000144288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HEU1513304.1"
                     /translation="MTFSFDTAAAQGAVIKVIGVGGGGGNAINRMVDEGVTGVEFIAA
                     NTDVQALSSTKAETVIQLGPKLTRGLGAGGQPEVGRKAAEESEETLTEAISGADMVFI
                     TAGMGGGSGTGAAPVIARIAKDLGALTVGVVTRPFGFEGSKRGQFAVEGINQLREHVD
                     TLLIISNNNLLEIVDKKTPLLEALSEADNVLRQGVQGITDLITNPGLINLDFADVKTV
                     MANKGNALMGIGIGSGEERVVEAARKAIYSPLLETTIDGAEDVIVNVTGGLDLTLIEA
                     EEASQIVNQAAGQGVNIWLGTSIDESMRDEIRVTVVATGVRQDRVEKVVAPQARSATN
                     YRETVKPAHSHGFDRHFDMAETVELPKQNPRRLEPTQASAFGDWDLRRESIVRTTDSV
                     VSPVERFEAPISQDEDELDTPPFFKNR"
     gene            28398..29069
                     /locus_tag="VU534_000675"
     CDS             28398..29069
                     /locus_tag="VU534_000675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HEU1513305.1"
                     /translation="MNVKENTELVFREVAEASLSAHRESGSVSVIAVTKYVDVPTAEA
                     LLPLGVHHIGENRVDKFLEKYEALKDRDVTWHLIGTLQRRKVKDVIQYVDYFHALDSV
                     KLAGEIQKRSDRVIKCFLQVNISKEESKHGFSREELLEILPELARLDKIEYVGLMTMA
                     PFEASSEQLKEIFKAAQDLQREIQEKQIPNMPMTELSMGMSRDYKEAIQFGSTFVRIG
                     TSFFK"
     gene            29079..29618
                     /locus_tag="VU534_000676"
     CDS             29079..29618
                     /locus_tag="VU534_000676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HEU1513306.1"
                     /translation="MSLKDRFDRFIDYFTEDEDSSLPYEKRDEPVFTSVNSSQEPALP
                     MNQPSQSAGTKENNITRLHARQQELANQSQRATDKVIIDVRYPRKYEDATEIVDLLAG
                     NESILIDFQYMTEVQARRCLDYLDGACHVLAGNLKKVASTMYLLTPVNVIVNVEDIRL
                     PDEDQQGEFGFDMKRNRVR"
     gene            29618..29881
                     /locus_tag="VU534_000677"
     CDS             29618..29881
                     /locus_tag="VU534_000677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000576515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HEU1513307.1"
                     /translation="MIFLIRMIYNAVDIYSLILVAFAVMSWFPGAYESSLGRWIVALV
                     KPVLAPLQRLPLQIAGLDLSVWVAIVLVRFLGENLVRFLAMIG"
     gene            29878..30663
                     /locus_tag="VU534_000678"
     CDS             29878..30663
                     /locus_tag="VU534_000678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HEU1513308.1"
                     /translation="MNKGIYQHFSIEDRPFLDKGMEWIKKVEDSYAPFLTPFINPHQE
                     KLLKILAKTYGLACSSSGEFVSSEYVRVLLYPDYFQPEFSDFEISLQEIVYSNKFEHL
                     THAKILGTVINQLGIERKLFGDILVDEERAQIMINQQFLLLFQDGLKKIGRIPVSLEE
                     RPFTEKIDKLEQYRELDLSVSSFRLDVLLSNVLKLSRNQANQLIEKKLVQVNYHVVDK
                     SDYTVQVGDLISVRKFGRLRLLQDKGQTKKEKKKITVQLLLSK"
     gene            30672..31460
                     /gene="divIVA"
                     /locus_tag="VU534_000679"
     CDS             30672..31460
                     /gene="divIVA"
                     /locus_tag="VU534_000679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DivIVA"
                     /protein_id="HEU1513309.1"
                     /translation="MPITSLEIKDKTFGTRFRGFDPEEVDEFLDIVVRDYEDLVRANH
                     DKNLRIKSLEERLSYFDEIKDSLSQSVLIAQDTAERVKQAAHERSNNIIHQAEQDAQR
                     LLEEAKYKANEILRQATDNAKKVAVETEELKNKSRVFHQRLKSTIESQLAIVESSDWE
                     DILRPTATYLQTSDEAFKEVVSEVLGEPIPAPIEEEPIDMTRQFSQAEMAELQARIEV
                     ADKELSEFEAQIKQEVEAPTPVVSPQVEEEPLLIQLAQCMKNQK"
     gene            31808..34600
                     /locus_tag="VU534_000680"
     CDS             31808..34600
                     /locus_tag="VU534_000680"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HEU1513310.1"
                     /translation="MKLKDTLNLGKTEFPMRAGLPTKEPVWQKEWEDAKLYQRRQELN
                     QGKPHFTLHDGPPYANGNIHVGHAMNKISKDIIVRSKSMSGFYAPFIPGWDTHGLPIE
                     QVLSKQGVKRKEMDLVEYLKLCREYALSQVDKQREDFKRLGVSGDWENPYVTLTPDYE
                     AAQIRVFGEMANKGYIYRGAKPVYWSWSSESALAEAEIEYHDLVSTSLYYANKVKDGK
                     GVLDTDTYIVVWTTTPFTITASRGLTVGADIDYVLVQPAGEARKFVVAAELLTSLSEK
                     FGWADVQVLETYRGQELNHIVTEHPWDTAVEELVILGDHVTTDSGTGIVHTAPGFGED
                     DYNVGIANNLEVAVTVDERGIMMKNAGPEFEGQFYEKVVPTVIEKLGNLLLAQEEISH
                     SYPFDWRTKKPIIWRAVPQWFASVSKFRQEILDEIEKVKFHSEWGKVRLYNMIRDRGD
                     WVISRQRAWGVPLPIFYAEDGTAIMVAETIEHVAQLFEEYGSSIWWERDAKDLLPEGF
                     THPGSPNGEFKKETDIMDVWFDSGSSWNGVVVNRPELTYPADLYLEGSDQYRGWFNSS
                     LITSVANHGVAPYKQILSQGFALDGKGEKMSKSLGNTIAPSDVEKQFGAEILRLWVTS
                     VDSSNDVRISMDILSQVSETYRKIRNTLRFLIANTSDFNPAQDTVAYDELRSVDKYMT
                     IRFNQLVKTIRDAYADFEFLTIYKALVNFINVDLSAFYLDFAKDVVYIEGAKSLERRQ
                     MQTVFYDILVKITKLLTPILPHTAEEIWSYLEFETEDFVQLSELPEVQTFANQEEILD
                     TWAAFMDFRGQAQKALEEARNAKVIGKSLEAHLTVYPNEVVKTLLEAVNSNVAQLLIV
                     SELTIAEGPAPEAALSFEDVAFTVERATGEVCDRCRRIDPTTAERSYQAVICDHCASI
                     VEENFAEAVAEGFEEK"
     gene            35003..35388
                     /locus_tag="VU534_000681"
                     /pseudo
     CDS             35003..35388
                     /locus_tag="VU534_000681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000769852.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            35923..36615
                     /locus_tag="VU534_000682"
     CDS             35923..36615
                     /locus_tag="VU534_000682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006703946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate mutase"
                     /protein_id="HEU1513311.1"
                     /translation="MVKLVFARHGESEWNKANLFTGWADVDLSEKGTQQAIDAGKLIK
                     EAGIEFDQAYTSVLKRAIKTTNLALEASDQLWVPVEKSWRLNERHYGGLTGKNKAEAA
                     EQFGDEQVHIWRRSYDVLPPNMDRDDEHSAHTDRRYASLDDSVIPDAENLKVTLERAL
                     PFWEDKIAPALKDGKNVFVGAHGNSIRALVKHIKGLSDDEIMDVEIPNFPPLVFEFDE
                     KLNVVSEYYLGK"
     gene            36668..39079
                     /locus_tag="VU534_000683"
     CDS             36668..39079
                     /locus_tag="VU534_000683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000620712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 95 protein"
                     /protein_id="HEU1513312.1"
                     /translation="MIRNKKQDYVLAYKQPASTTYMGWEEEALPIGNGSLGAKVFGLI
                     GAERIQFNEKSLWSGGPLPDSSDYQGGNLQDQYVFLAEIRQALEKRDYNLAKELAEQH
                     LIGPKTSQYGTYLSFGDIHIEFSQQGTTLSQVTDYQRQLNISKALATTSYVYKGTRFE
                     RKAFASFPDDLLVQCFTKEGLETLDFTIELSLTCDLASDGKYEQEKSDYKECKLDITD
                     SHILMKGRVKDNDLRFASYLAWETDGDIRVWSDRVQISGASYANLFLAAKTDFAQNPA
                     SNYRKKLDLEQQVIDLVDTAKEKGYTQLKSRHIEDYQALFQRVQLDLEADVDASTTDD
                     LLKNYKPQEGQALEELFFQYGRYLLISSSRDCPDALPANLQGVWNAVDNPPWNSDYHL
                     NVNLQLNYWPAYVTNLLETVFPVINYVDDLRVYGRLAAVKYAGIVSQKGEENGWLVHT
                     QATPFGWTAPGWDYYWGWSPAANAWMMQTVYEAYLFYRDQDYLREKIYPMLRETVRFW
                     NAFLHKDQQAQRWVSSPSYSPEHGPISIGNTYDQSLIWQLFHDFIQAAQELGLDEDLL
                     TEVKEKSDLLNPLQITQSGRIREWYEEEEQYFQNEKVEAQHRHASHLVGLYPGNLFSY
                     KGQEYIEAARASLNDRGDGGTGWSKANKINLWARLGDGNRAHKLLAEQLKTSTLQNLW
                     CSHPPFQIDGNFGATSGMAEMLLQSHAAYLVPLAALPDAWSTGSVSGLMARGHFEVSM
                     SWEDKKLLQLTILSRSGGDLRVSYPDIEKSVIKMNQEKIKAKCMGKDCISVATAEGDL
                     VQFYF"
     gene            39329..40030
                     /locus_tag="VU534_000684"
     CDS             39329..40030
                     /locus_tag="VU534_000684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU1513313.1"
                     /translation="MAYIEMKHCYKRYQVGDTEIVANCDVNFEIEKGELVIILGASGA
                     GKSTVLNLLGGMDTNDEGEIWIDGVNIADYSSHQRTNYRRNDVGFVFQFYNLVSNLTA
                     KENVELASEIVTDALNPDQALTDVGLAHRLNNFPAQLSGGEQQRVSIARAVAKNPKIL
                     LCDEPTGALDYQTGKQVLKILQDMSRQKGATVIIVTHNGALAPIADRVIQMHDASVKD
                     VVLNQHPQDIDSLEY"
     gene            40032..42740
                     /locus_tag="VU534_000685"
     CDS             40032..42740
                     /locus_tag="VU534_000685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HEU1513314.1"
                     /translation="MIKRKTYWKDLVQSFTGSKGRFLSILILMMLGSLALVGLKVTSP
                     NMEATANAYLTTAQTLDLAVMSNYGLDQADQEELKQTEGAEVEFGYLTDVTMDNGQDA
                     IRLYSKPERISTFQLRKGRLPQSDKEIALATHLQGQYSVGQEISFKEKEEGHSSLKDH
                     TYTITGFVDSAEILSQRDMGYAGSGSGTLTAYGVILPSQFDQKVYNIARLKYQDLAGL
                     NAFSSAYEEKSKQHQEELEQILSDNGKVRLQLLKKEGQESLDKGQETLDKAQTNLQEG
                     KRRLAAAQARIQAQESQLALFPQVQREQASAQLTQAKQELGKEEDKLKQAEQNLAQEK
                     EKLEKHQQVLDDLAEPRYQVYNRQTMPGGQGYLMYSNASSSIRAVGNIFPVVLYAVAA
                     MVTFTTMTRFVDEERTHAGIFKALGYRSKDIIAKFLLYGLVAGTVGTALGSILGHYLL
                     ASVISSVITKGMVVGETQIQFYWTYSLLAFVLSLLASVLPAYLVAWRELHDEAAQLLL
                     PKPPVKGAKILLERIGFIWRRLSFTHKVTARNIFRYKQRMLMTIFGVAGSVALLFAGL
                     GIQSSVAGVPSKQFQQIQQYQMLVSENPSATNQDKVELAEVLKGQEILAYQKIYSKAL
                     YKDFKGKAGLQNITLMMIEKEDLTPFIHLQHHQQELTLKDGIVITAKLAQLAGVKVGQ
                     TLEIEGKELKVVAITENYVGHFIYMSQASYEQLYGQLPQANTYLVSLRDTSATSIESQ
                     AGLLMNQSAVSSVVQNASAIRLFDSIASSLNQTMTILVIVSVLLAIVILYNLTNINVA
                     ERIRELSTIKVLGFHNNEVTLYIYRETIVLSLVGIVLGLIAGFYLHQFLIQMISPATI
                     LFYPQVGWEVYVIPVAAVSIILTLLGFFVNYYLRKVDMLEALKSVE"
     gene            complement(42836..43327)
                     /gene="tpx"
                     /locus_tag="VU534_000686"
     CDS             complement(42836..43327)
                     /gene="tpx"
                     /locus_tag="VU534_000686"
                     /EC_number="1.11.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol peroxidase"
                     /protein_id="HEU1513315.1"
                     /translation="MVTFLGNPVSFTGKQLQVGDKALDFSLTTTDLSKKSLADFDGKK
                     KVLSVVPSIDTGICSTQTRRFNEELAGLDNTVVLTVSMDLPFAQKRWCGAEGLDNAIM
                     LSDYFDHSFGRDYALLINEWHLLARAVFVLDTDNTIRYVEYVDNINSEPNFEAAIAAA
                     KAL"
     gene            complement(43450..44379)
                     /gene="psaA"
                     /locus_tag="VU534_000687"
     CDS             complement(43450..44379)
                     /gene="psaA"
                     /locus_tag="VU534_000687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000733059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding
                     lipoprotein/adhesin PsaA"
                     /protein_id="HEU1513316.1"
                     /translation="MKKLGTLLVLFLSAIILVACASGKKDTTSGQKLKVVATNSIIAD
                     ITKNIAGDKIDLHSIVPIGQDPHEYEPLPEDVKKTSEANLIFYNGINLETGGNAWFTK
                     LVENAKKTENKDYFAVSDGVDVIYLEGQNEKGKEDPHAWLNLENGIIFAKNIAKQLSA
                     KDPNNKEFYEKNLKEYTDKLDKLDKESKDKFNKIPAEKKLIVTSEGAFKYFSKAYGVP
                     SAYIWEINTEEEGTPEQIKTLVEKLRQTKVPSLFVESSVDDRPMKTVSQDTNIPIYAQ
                     IFTDSIAEQGKEGDSYYSMMKYNLDKIAEGLAK"
     gene            complement(44411..45259)
                     /locus_tag="VU534_000688"
     CDS             complement(44411..45259)
                     /locus_tag="VU534_000688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000559784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HEU1513317.1"
                     /translation="MIAEFIDGLQKFHFLQNALITAIVVGIVAGAVGCFIILRGMSLM
                     GDAISHAVLPGVALSFILGLDFFIGAIVFGLLAAIIITYIKGNSIIKSDTAIGITFSS
                     FLALGIILIGVAKSSTDLFHILFGNILAVQDTDMFITMGVGAAILLLIWIFFKQLLIT
                     SFDELLAKAMGMPVNFYHYLLMVLLTLVSVTAMQSVGTILIVAMLITPAATAYLYANS
                     LKSMIFLSSTFGATASVLGLFIGYSFNVAAGSSIVLTAASFFLISFFIAPKQRYLKLK
                     NKHLLK"
     gene            complement(45256..45978)
                     /locus_tag="VU534_000689"
     CDS             complement(45256..45978)
                     /locus_tag="VU534_000689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HEU1513318.1"
                     /translation="MIRIENLSVSYKETLALKDISLVLHGPTITGIIGPNGAGKSTLL
                     KGMLGIIPHQGQAFLDDKEVKKSLHRIAYVEQKINIDYNFPIKVKECVSLGLFPSIPL
                     FRSLKAKHWKKVQEALEIVGLADYAERQISQLSGGQFQRVLIARCLVQEADYILLDEP
                     FAGIDSVSEEIIMNTLRDLKKAGKTVLIVHHDLSKIPHYFDQVLLVNREVIAFGPTKE
                     TFTETNLKEAYGNQLFFNGGDL"
     gene            46269..48161
                     /gene="pepO"
                     /locus_tag="VU534_000690"
     CDS             46269..48161
                     /gene="pepO"
                     /locus_tag="VU534_000690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endopeptidase PepO"
                     /protein_id="HEU1513319.1"
                     /translation="MTRYQDDFYDAINGEWQQTAEIPADKSQTGGFVDLDQEIEDLML
                     ATTDKWLAGEEVPEDAILENFVKYHRLVRDFDKREADGITPVLPLLKEFQELETFADF
                     TAKLAEFELAGKPNFLPFGVSPDFMDARINVLWASAPSTILPDTTYYAEEHPQREELL
                     TLWKESSANLLKAYDFSDEEIEDLLEKRLELDRRVAAVVLSNEESSEYAKLYHPYSYE
                     DFKKFAPALPLDDFFKAVIGQLPDKVIVDEERFWQAAEQFYSEEAWSLLKATLILSVV
                     NLSTSYLTEDIRVLSGAYSRALSGVPEAKDKVKAAYHLAQEPFKQALGLWYAREKFSP
                     EAKADVEKKVATMIDVYKERLLKNDWLTPETCKQAIVKLNVIKPYIGYPEELPARYKD
                     KVVNETASLFENALAFARVEIKHSWSKWNQPVDYKEWGMPAHMVNAYYNPQKNLIVFP
                     AAILQAPFYDLHQSSSANYGGIGAVIAHEISHAFDTNGASFDENGSLKDWWTESDYAA
                     FKEKTQKVIDQFDGQDSYGATINGKLTVSENVADLGGIAAALEAAKREADFSAEEFFY
                     NFGRIWRMKGRPEFMKLLASVDVHAPAKLRVNVQVPNFDDFFTTYDVKEGDGMWRSPE
                     ERVIIW"
     gene            complement(48284..48913)
                     /locus_tag="VU534_000691"
     CDS             complement(48284..48913)
                     /locus_tag="VU534_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HEU1513320.1"
                     /translation="MKIHKTVNPVAYENTYYLEGEKHLIVVDPGSHWEAIRQTIEKIN
                     KPICAILLTHAHYDHIMSLDLVRETFGNPPVYIAESEASWLYTPVDNLSGLPRHDDMA
                     DVVTKPAEHTFVFHEEYQLEEFRFKVLPTPGHSIGGVSLVFPDAHLVLTGDALFRETI
                     GRTDLPTGSMEQLLHSIQTQLFTLPNYDVYPGHGPATTIAHEKAFNPFF"
     gene            49872..52094
                     /locus_tag="VU534_000692"
     CDS             49872..52094
                     /locus_tag="VU534_000692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019316080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HEU1513321.1"
                     /translation="MPKEVNLTGEEVVALTKEYLTEEDVHFVHKALVYAVECHSGQYR
                     KSGEPYIIHPIQVAGILAKLKLDAVTVACGFLHDVVEDTDATLDDLEREFGPDVRMIV
                     DGVTKLGKVEYKSIEEQLAENHRKMLMAMSEDIRVILVKLSDRLHNMRTLKHLRKDKQ
                     ERISKETMEIYAPLAHRLGISSVKWELEDLSFRYLNPTEFYKITHMMKEKRREREALV
                     DEVVTKLEEYTTERHLKGKIYGRPKHIYSIFRKMQDKRKRFEEIYDLIAIRCILDTQS
                     DVYAMLGYVHEFWKPMPGRFKDYIANRKANGYQSIHTTVYGPKGPIEFQIRTKEMHEV
                     AEYGVAAHWAYKKGIKGQVNSKESAIGMNWIKEMMELQDQADDAKEFVDSVKENYLAE
                     EIYVFTPDGAVRSLPKDSGPIDFAYEIHTKVGEKATGAKVNGRMVPLTTKLKTGDQVE
                     IIANPNSFGPSRDWLNMVKTSKARNKIRQFFKNQDKELSVNKGREMLMAQFQENGYVA
                     NKFMDKRHMDQVLQKTSYKTEDSLFAAIGFGEIGAITVFNRLTEKERREEERAKAKAE
                     AEELVKGGEVKVENKETLKVKHEGGVVIEGASGLLVRIAKCCNPVPGDDIVGYITKGR
                     GVAIHRVDCMNLRAQENYEQRLLDVEWEDQYPSSNKEYMAHIDIYGLNRTGLLNDVLQ
                     VLSNTTKNISTVNAQPTKDMKFANIHVSFGIANLSTLTTVVDKIKSVPEVYSVKRTNG
                     "
     gene            52124..52567
                     /locus_tag="VU534_000693"
     CDS             52124..52567
                     /locus_tag="VU534_000693"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-tyrosyl-tRNA(Tyr) deacylase"
                     /protein_id="HEU1513322.1"
                     /translation="MKIIIQRVKKAQVSIEGQIQGKINQGLLLLVGVGPEDQEEDLDY
                     AVRKLVNMRIFSDAEGKMNLSVKDIEGEILSISQFTLFADTKRGNRPAFTGAAKPDMA
                     SDFYDAFNQKLAQEVPVQTGIFGADMQVELVNNGPVTIILDTKKR"
     gene            complement(52834..53019)
                     /locus_tag="VU534_000694"
     CDS             complement(52834..53019)
                     /locus_tag="VU534_000694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000720032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1513323.1"
                     /translation="MKKIIFIKTIQLLVIDGIMLAFLTFKRGLTWDWILIYSGWLIFF
                     HPVLLTYLSNQLCDHFS"
     gene            complement(53038..53451)
                     /locus_tag="VU534_000695"
     CDS             complement(53038..53451)
                     /locus_tag="VU534_000695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000737919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1513324.1"
                     /translation="MKKLYRIHFIAIAVIDLLLFAFFITRLETSFEWLLLSGLIFFLA
                     QGLLLFLLVVRLKHQFAEIYPQINKKIRFYYLGVLTIDFLFFVLLAFISSQRFSSLMP
                     IITACHSTFYYMTADYLRENYPDFYDKHISLWECL"
     gene            complement(53582..54229)
                     /locus_tag="VU534_000696"
     CDS             complement(53582..54229)
                     /locus_tag="VU534_000696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide mononucleotide transporter"
                     /protein_id="HEU1513325.1"
                     /translation="MVVGIAIASGYLNSHLDKFVDWGSWTALVPFGLISVTNVGISML
                     STRFTGKLSKWGNYFGIVNTILSGAIDYILGNKAAIITYPVTFLIYTFAIKKWEASQE
                     GRPNQMSQKQVKLAAIIISIIAFLFAFVTNYIGYGGKMNLLAYVTTIAFALSLIANAL
                     NALKLTTQWGFWLIYNFVQLTKAGIQGNFANIGKYIFYILNAIGALFVWNDEEVR"
BASE COUNT        16626 a         9768 c        11992 g        16011 t
ORIGIN      
        1 aaaaatagaa ggagatagca ggttttcaag cctgctatct ttttttgatg acattcaggc
       61 tgatacgaaa tcataagagg tctgaaacta ctttcagagt agtctgttct ataaaatata
      121 gtagattgaa ataagatgtg aacaactcta tcaggaaagt caaattaatt tatagaatta
      181 ttttagcagt caaggtgtac tgttatagat tcaatatatt atatgactat taaccttgtc
      241 ttctcctaaa attgactttc ttgttttctt atcttgtcca ctcgaaacaa gtattgtaag
      301 aatttgatta tttttgaaag tacttttaat atacttgata tagttaaaaa agatttgaaa
      361 ctaaattcca aattagaaaa agacttgaaa tactaaaaaa aaaaagtata ctctaattga
      421 aaacggtaac aaaactaatt tagagaatga aatatagagt atttctctct taaaagtttt
      481 tggtgaaacg agatgtagaa aggagattta gccaaagagt ctattagtgc tagaataata
      541 gattagaatt attttagaaa aacgaagtga gcagcttata aattcaagtc cccaaataga
      601 ttcatactag tatcttttgc aaaaaataaa gggcgacttc cttcatgaat atcaatttca
      661 tctataagga aggtagctaa ttgaactaac ttatttattc tgtttgtcgc tagaaaaatc
      721 agacctcctt gtgaagattg aggagatact taatgaaaat caaagaagaa actagcaagc
      781 tagtagcaga ttgcccaaaa caccgctttg aggttgtaga taagactgac ctatataatc
      841 caaggtgaag cgactgtggt ttgaagagat tttcaaagag tataggctag agagtagtgt
      901 ttttatgtcc ttctagtaga aaatgctaga cagaagaatg gggaacttgg ataggaaaaa
      961 tagattgaga aaggaggtta gaagagatga ttattacaaa aattagccgt ttaggaactt
     1021 atgtgggagt aaatccacat tttgcaacat taatagattt tctagaaaaa acaggactag
     1081 aaaatttaac agaaggttcg attgctatcg atggtaatcg attgtttggg aattgcttta
     1141 cttatctagc agatggtcaa gcaggggctt tctttgaaac ccaccaaaaa tatttggata
     1201 ttcatttagt tttggaaaac gaagaagcca tggctgttac atcgccggaa aatgtaagcg
     1261 ttacccaaga atatgatgaa gagaaagata ttgaattata cacagggaaa gtggaacagt
     1321 tggttcattt gagagctggc gaatgcctca tcacttttcc agaagattta catcaaccca
     1381 aggttcgtat aaatgatgaa cctgtgaaaa aagttgtctt taaagttgcg atttcttaat
     1441 gtagaaagag aagaacgatg aaaaaaatga gaaagttttt atgtctagct ggaattgcgc
     1501 tagcggctgt tgccttggta gcttgttcag gaaaaaaaga agctacaact agtactgaac
     1561 caccaacaga attatctggt gagattacaa tgtggcactc ctttactcaa ggaccccgtt
     1621 tagaaagtat tcaaaaatca gcagatgctt tcatgcaaaa gcatccaaaa acgaaaatca
     1681 agattgaaac attttcttgg aatgacttct atactaaatg gactacaggt ttagcaaatg
     1741 gaaatgtgcc agatatcagt acagctcttc ctaaccaagt aatggaaatg gtcaactcag
     1801 atgctttggt tccgctaaat gattctatca agcgtattgg acaagataaa tttaacgaaa
     1861 ctgccttaaa tgaagcaaaa atcggagatg attactactc tgttcctctt tattcacatg
     1921 cacaagtcat gtgggttaga acagatttgt taaaagaaca taatattgag gttcctaaaa
     1981 cttgggatca actctatgaa gcttctaaaa aattgaaaga agctggagtt tatggcttgt
     2041 ctgttccgtt tggaacaaat gacttaatgg caacacgttt cttgaacttc tacgtacgta
     2101 gtggtggagg aagcctctta acaaaagatc ttaaagcaga cttgacaagc caacttgctc
     2161 aagatggtat taaatactgg gttaaattgt ataaagaaat ctcacctcaa gattctttga
     2221 actttaatgt ccttcaacaa gctaccttgt tctatcaagg aaaaacagca tttgacttta
     2281 actctggctt ccatatcgga ggaattaatg ccaacagtcc tcaattgatt gattcgattg
     2341 atgcttatcc tattccaaaa atcaaagagt ctgataaaga ccaaggaatt gaaacctcaa
     2401 acattccaat ggttgtttgg aaaaattcaa aacatccaga agttgctaaa gcattcttag
     2461 aagcacttta taatgaagaa gactacgtta aattccttga ttcaactcca gtaggtatgt
     2521 tgccaactat taaggggatt agcgattctg cagcctataa agaaaatgaa actcgtaaga
     2581 aatttaaaca tgctgaagaa gtaattactg aagctgttaa aaaaggtact gctattggtt
     2641 atgaaaatgg gccaagtgta caagctggta tgttgactaa ccaacacatt attgaacaaa
     2701 tgttccaaga tatcattaca aatggaacag atcctatgaa agcagcaaaa gaagcagaaa
     2761 aacaattaaa tgatttattt gaggctgttc agtagatgta aaagactaga aaataggtgg
     2821 gatagtgagc tgaaaagctc tagcccaatc ttgtaaaaga agggagaagg agaatggtta
     2881 aagaacgtaa tttaactcgc tggatatttg ttttgccagc tatgattatc gtaggattac
     2941 tctttgttta tccgtttttc tcgagtattt tttatagctt taccaataag catttgatta
     3001 tgcctaatta taaatttgtt ggtttggcta actataaagc tgtgctatca gatcccaact
     3061 tctttaatgc gttctttaat tcaattaagt ggaccgtttt ctcattagtt ggtcaagttt
     3121 tagtagggtt tgtattggct ttagctcttc acagagtacg ccacttcaag aaattatata
     3181 ggacattatt gattgttcct tgggcatttc ctaccatcgt tattgccttc tcttggcagt
     3241 ggattctaaa cggggtttat ggctacttac ctaatctaat cgtaaaatta ggtttaatgg
     3301 aacatacacc tgcatttttg acagatagta catgggcatt cctatgtttg gtgtttatca
     3361 acatttggtt tggagcacca atgattatgg ttaatgtgct ttcagctttg caaacagtac
     3421 cagaagaaca atttgaggct gctaagatag atggtgcttc aagttggcag gtgttcaagt
     3481 ttatcgtctt tccacatatt aaagtggttg taggacttct agttgttttg agaactgtat
     3541 ggatctttaa taactttgac attatctacc tcattactgg tggtggacca gccaatgcta
     3601 caacgacgct tccaattttt gcttacaacc tgggctgggg aactaaattg ttgggtcgtg
     3661 cttcagcagt tacagtactg ctctttatct tcttggtggc gatttgcttt atctactttg
     3721 ctatcatcag taagtgggaa aaggagggta gaaaataatg aagaagaaat ccagtattta
     3781 tttagatatt ctctcacatg tacttttagt tggtgcgacc atcgttgcag ttttcccatt
     3841 ggtatggatt atcatatctt ctgtcaaagg gaaaggggaa ttaactcagt atccaacacg
     3901 attttggcct gaacagttta cattagatta tttcactcat gttatcaacg atttgcactt
     3961 cattgataac attcgaaaca gtttaatcat tgccttggct acaaccctta ttgcgattat
     4021 tatttctgct atggcagcct atggtattgt tcgattcttt cctaaattgg gagcaatcat
     4081 gtcgagacta ctcgtcatta cctacatttt cccaccaatt ttgttagcaa ttccctattc
     4141 aattgccatt gctaaagttg ggttaacaaa tagtttattt ggcttgatga tggtttatct
     4201 atcttttagt gttccatatg cagtttggct cttagttgga tttttccaaa cagttccaat
     4261 tggaattgaa gaagcggcta gaattgatgg tgcaaataaa tttgttacgt tttataaagt
     4321 tgtgctaccg attgtagcac caggtattgt agcaacagct atttatacat ttatcaatgc
     4381 ttggaatgaa ttcctgtatg ccttgatttt gattaacaat acaggaaaga tgacagtagc
     4441 agtagccctt cgttcactta atggttcaga aatactagac tggggagata tgatggcagc
     4501 gtctgttatt gtagttcttc catcaattat tttcttctct atcatccaaa ataagattgc
     4561 aagtggatta tcagaaggat ctgtgaagta gacgaaagaa ggaaaaaaat gaataaaaga
     4621 ggtctttatt caaaactagg aatttccgtt gtaggcatta gtcttttaat gggagtcccc
     4681 actttgattc atgcgaatga attaaactat ggtcaactgt ccatatctcc tatttttcaa
     4741 ggaggttcat atcaactgaa caataagagt atagatatca gctctttgtt attagataaa
     4801 ttgtctggag agagtcagac agtagtaatg aaatttaaag cagataaacc aaactctctt
     4861 caagctttgt ttggcctatc taatagtaaa gcaggcttta aaaataatta cttttcaatt
     4921 ttcatgagag attctggtga gataggtgta gaaataagag acgcccaaaa gggaataaat
     4981 tatttatttt ccagaccagc ttcattatgg ggaaaacata aaggacaggc agttgaaaat
     5041 acactagtat ttgtatctga ttctaaagat aaaacataca caatgtatgt taatggaata
     5101 gaagtgttct ctgaaacagt tgatacattt ttgccaattt caaatataaa tggtatagat
     5161 aaggcaacac taggagctgt taatcgtgaa ggtaaggaac attacctcgc aaaaggaagt
     5221 attgatgaaa tcagtctatt taacaaagca attagtgatc aggaagtttc aactattccc
     5281 ttgtcaaatc catttcagtt aattttccaa tcaggagatt ctactcaagc taactatttt
     5341 agaataccga cactatatac attaagtagt ggaagagttc tatcaagtat tgatgcacgt
     5401 tatggtggga ctcatgattc taaaagtaag attaatattg ccacttctta tagtgatgat
     5461 aatgggaaaa cgtggagtga gccaattttt gctatgaagt ttaatgacta tgaggagcag
     5521 ttagtttact ggccacgaga taataaatta aagaatagtc aaattagtgg aagtgcttca
     5581 ttcatagatt catccattgt tgaagataaa aaatctggga aaacgatatt actagctgat
     5641 gttatgcctg cgggtattgg aaataataat gcaaataaag ccgactcagg ttttaaagaa
     5701 ataaatggtc attattattt aaaactaaag aagaatggag ataacgattt ccgttataca
     5761 gttagagaaa atggtgtcgt ttataatgaa acaactaata aacctacaaa ttatactata
     5821 aatgataagt atgaagtttt ggagggagga aagtctttaa cagtcgaaca atattcggtt
     5881 gattttgata gtggctcttt aagagaaagg cataatggaa aacaggttcc tatgaatgtt
     5941 ttctacaaag attcgttatt taaagtgact cctactaatt atatagcaat gacaactagt
     6001 cagaatagag gagagagttg ggaacaattt aagttgttgc ctccgttctt aggagaaaaa
     6061 cataatggaa cttacttatg tcccggacaa ggtttagcat taaaatcaag taacagattg
     6121 atttttgcaa catatactag tggagaacta acctatctca tttctgatga tagtggtcaa
     6181 acatggaaga aatcctcagc ttcaattccg tttaaaaatg caacagcaga agcacaaatg
     6241 gttgaactga gagatggtgt gattagaaca ttctttagaa ccactacagg taagatagct
     6301 tatatgacta gtagagattc tggagaaaca tggtcgaaag tttcgtatat tgatggaatc
     6361 caacaaactt catatggcac acaagtatct gcaattaaat actctcaatt aattgatgga
     6421 aaagaagcag tcattttgag tacaccaaat tctagaagtg gccgcaaggg aggccaatta
     6481 gttgtcggtt tagtcaataa agaagatgat agtattgatt ggaaatacca ctatgatatt
     6541 gatttgcctt cgtatggtta tgcctattct gcgattacag aattgccaaa tcatcacata
     6601 ggtgtactgt ttgaaaaata tgattcgtgg tcgagaaatg aattgcattt aagcaatgta
     6661 gttcagtata tagatttgga aattaatgat ttaacaaaat aaaggagaaa aacatggtta
     6721 aatacggtgt tgttggaaca gggtattttg gagctgaatt ggctcgctac atgcaaaaga
     6781 atgatggagc agagattact cttctctatg atccagataa tgcagaggcg attgcagaag
     6841 aattgggagc aaaagtagca agttccttag atgagttggt ttctagcgat gaagtagatt
     6901 gtgttatcgt cgcaactcca aataatcttc ataaggaacc ggttattaag gctgcacagc
     6961 atggtaaaaa tgttttctgt gaaaaaccaa ttgcgctttc ttatcaagat tgtcgcgaga
     7021 tggtagatgc gtgtaaagaa aacaatgtaa cctttatggc aggacatatt atgaatttct
     7081 ttaatggtgt tcatcatgca aaagaactca ttaatcaagg agttatcgga gacgttctat
     7141 attgtcatac agctcgtaat ggttgggaag aacaacaacc gtcagtatca tggaaaaaaa
     7201 ttcgtgaaaa atcaggtggt cacttgtatc accacatcca tgaattggat tgcgttcaat
     7261 tccttatggg gggcatgcct gaaactgtaa ccatgacagg tggaaatgtg gcccatgaag
     7321 gtgaacattt cggtgatgaa gatgatatga tttttgtcaa tatggaattt tctaataagc
     7381 gttttgcctt gttagaatgg ggttcagctt atcgttgggg tgaacattat gtcttaatcc
     7441 aaggaagcaa aggtgccatc cgcttagact tattcaactg taaaggaact cttaagctag
     7501 atgggcaaga aagctatttc ttgattcacg aatcgcaaga agaagatgat gatcggactc
     7561 gtatctatca tagtacagag atggatggag caattgctta tggtaaacca ggtaaacgta
     7621 ctccattatg gctatcatct gtcattgata aagaaatgcg ctatctgcat gagattatgg
     7681 aaggagctcc agtatcagaa gaatttgcaa aacttttgac aggtgaagct gccctagaag
     7741 caattgctac tgcagatgct tgtacccagt ctatgtttga agatcgcaaa gtaaaattgt
     7801 cagaaattgt aaaataaatt ttggtattct cctatttata ggtcgacttg ctcctctgaa
     7861 agtactttta gaggagctgt ttgactttgc tagtttttga aactgaaatc tattatacta
     7921 caaactattg aaagcgtttt aattttaagg tataataatc tcatagaaat aaagaaaagg
     7981 aggaaagagg atgccacaga ttagcaaaga agccttgatt gagcaaatca aagatggaat
     8041 catcgtttct tgtcaggctc ttcctcatga accgctttat acagaagcgg gaggggtgat
     8101 tcccttgctg gtcaaagcgg ctgagcaagg tggagcagtc ggtatccgag caaacagtgt
     8161 tcgcgatatc aaggaaatta aggaagtcac taaacttcca atcattggga ttatcaaacg
     8221 tgattatcca cctcaggaac ccttcatcac ggctactatg aaagaagttg atgaattggc
     8281 agaactggac atcgaggtga ttgctctgga ttgtaccaag cgtgaacgct acgatggttt
     8341 ggaaattcaa gagttcattc gtcaggttaa ggagaaatat cctaatcagc ttttgatggc
     8401 tgatactagt atcttcgaag aagggctagc agctgtagaa gcaggaattg actttgtcgg
     8461 aacaacctta tcaggctaca catcctacag tccaaaagta gacggtccag attttgaatt
     8521 gattaagaaa ctctgtgatg ctggtgtaga tgtcattgca gaaggaaaaa ttcatacacc
     8581 agaacaagcc aaacaaatcc ttgaatatgg agtgcgaggc atcgttgttg gtggcgccat
     8641 tactagacca aaagagatta cagaacgctt cgttgctagt cttaaataag atgtgagggg
     8701 gagttttatg tttaaagttt tacaaaaagt tggaaaagct tttatgttac ctatagctat
     8761 acttcctgca gcaggtctac ttttggggat tggtggtgca ctttcaaacc caaccacgat
     8821 agcaacttat ccaatactag acaatagtat ttttcaatca atattccaag taatgagctc
     8881 tgcaggagag gttgtattca gtaatttgtc actacttctc tgtgtgggat tatgtattgg
     8941 cttagcgaaa cgagataaag gaaccgctgc gttagcagga gtaactggtt acttagttat
     9001 gactgcaacg atcaaagctt tggtaaaact ttttatggca gaaggatctg caattgatac
     9061 tggagttatt ggagcattag ttgtcggaat agttgccgta tatttgcaca accgatataa
     9121 caatattcaa ttaccttccg ctttaggatt ctttggaggt tcacgcttcg ttcctattgt
     9181 tacatcgttc tcttctatct tgattggctt tgtcttcttt gttatttggc cacctttcca
     9241 acaacttctt gtttctacag gtggatatat ttctcaggcg ggtccaattg gaacttttct
     9301 atatggattt ttaatgagac tttctggagc agtaggctta catcatataa tttaccctat
     9361 gttttggtat actgaacttg gtggtgttga aactgttgca ggacaaacag tggttggagc
     9421 tcaaaaaata ttttttgctc aattagccga tttggcccat tctggattat ttacagaagg
     9481 aacaaggttt tttgcaggtc gtttctcaac aatgatgttc ggtttaccgg ctgcctgttt
     9541 agcgatgtac catagtgttc ctaaaaatcg tcgtaaaaaa tacgcgggtt tgttttttgg
     9601 agttgcttta acatctttta ttaccggtat tacagaacca attgaattta tgtttctatt
     9661 cgtcagtccg gttctatatg ttgttcacgc attccttgat ggtgttagct tctttattgc
     9721 agacgtctta aatatttcaa taggaaacac attttcagga ggtgtaatcg atttcacttt
     9781 atttggaatt ttgcagggga acgctaagac gaattgggtt cttcagattc catttggact
     9841 tatttggagt gttttgtatt atattatttt tagatggttc attactcaat tcaacgttct
     9901 aacgccaggg cgaggagaag aagtagattc taaagaaatt tctgaatccg cagattcaac
     9961 ttcaaatact gcagattatt taaaacagga tagcctacaa attatcagag ccttgggtgg
    10021 atcaaataat atagaagatg tagatgcttg tgtgacacgt ttacgtgtag ctgtaaaaga
    10081 agttaatcaa gttgataaag cacttttaaa acaaattggt gcagttgatg tcttagaagt
    10141 gaagggtggc attcaagcaa tctatggagc aaaagcaatc ttatataaaa atagtattaa
    10201 tgaaatttta ggtgtagatg attaagtact tactgactta ataaaaaaca gaggagagtg
    10261 atggatgagt aggatgaaat gaaatcgcat acaagaaata aagaactcat tatccaagtt
    10321 ggatacgctt attacatagg agaatacaaa tgaaatttag aaaattagct tgtacagtac
    10381 ttgcgggtgc tgcggttctt ggtcttgctg cttgtggcaa ttctggcgga agtaaagatg
    10441 ctgccaaatc aggtggtgac ggtgccaaaa cagaaatcac ttggtgggca ttcccagtat
    10501 ttacccaaga aaaaactggt gacggtgttg gaacttatga aaaatcaatc atcgaagcgt
    10561 ttgaaaaagc aaacccagat ataaaagtga aattggaaac catcgacttc aagtcaggtc
    10621 ctgaaaaaat cacaacagcc atcgaagcag gaacagctcc agacgtactc tttgatgcac
    10681 caggacgtat catccaatac ggtaaaaacg gtaaattggc tgagttgaat gacctcttca
    10741 cagatgaatt tgttaaagat gtcaacaatg aaaacatcgt acaagcaagt aaagctggag
    10801 acaaggctta tatgtatccg attagttctg ccccattcta catggcaatg aacaagaaaa
    10861 tgttagaaga tgctggagta gcaaaccttg taaaagaagg ttggacaact gatgattttg
    10921 aaaaagtatt gaaagcactt aaagacaagg gttacacacc aggttcattg ttcagttctg
    10981 gtcaaggggg agaccaagga acacgtgcct ttatctctaa cctttatagc ggttctgtaa
    11041 cagatgaaaa agttagcaaa tatacaactg atgatcctaa attcgtcaaa ggtcttgaaa
    11101 aagcaactag ctggattaaa gacaatttga tcaataatgg ttcacaattt gacggtgggg
    11161 cagatatcca aaactttgcc aacggtcaaa catcttacac aatcctttgg gcaccagctc
    11221 aaaatggtat ccaagctaaa cttttagaag caagtaaggt agaagtggta gaagtaccat
    11281 tcccatcaga cgaaggtaag ccagctcttg agtaccttgt aaacgggttt gcagtattca
    11341 acaataaaga cgacaagaaa gtcgctgcat ctaagaaatt catccagttt atcgcagatg
    11401 acaaggagtg gggacctaaa gacgtagttc gtacaggtgc tttcccagtc cgtacttcat
    11461 ttggaaaact ttatgaagac aaacgcatgg aaacaatcag cggctggact caatactact
    11521 caccatacta caacactatt gatggatttg ctgaaatgag aacactttgg ttcccaatgt
    11581 tgcaatctgt atcaaatggt gacgaaaaac cagcagatgc tttgaaagcc ttcactgaaa
    11641 aagcgaacga aacaatcaaa aaagctatga aacaatagtc cttagttatt ctataaaaag
    11701 tagtttttta aagaacctaa gagtgtatac ccccttttcc ctctacacag atagtgtaag
    11761 aaaagggggc ttttgtttaa aatgtaagaa actgtcacga aattaaaatg aagttcttac
    11821 ataagcgaat cataaaaaat ttcattttga ttttaaaaca gttcaagaaa gtcaaaaaat
    11881 tattctattt gaaagagagg tgccgactgt gaaagtcaat aaaatccgta tgcgggaaac
    11941 agtgatttcc tacgctttcc tagcaccagt attattcttc tttgtcatct ttgtgttggc
    12001 tccgatggtg atgggcttca ttacaagttt ctttaactac tcaatgacta aatttgagtt
    12061 tgtaggcttg gataactata tccgtatgtt taaagatcct gtctttacaa aatctctgat
    12121 taacacagtt attttggtta ttggatctgt accagttgtt gttctattct cactctttgt
    12181 agcatctcag acctatcatc aaaatgtcat tgccagatcc ttctaccgtt tcgtcttctt
    12241 ccttcctgtt gtaacgggta gtgttgccgt gacagttgtt tggaaatgga tttatgaccc
    12301 actatcaggg attctaaact ttgtccttaa gtccagccac atcatcagcc aaaacatttc
    12361 ttggttggga gataaaaact gggcattgat ggcgattatg attattctct tgaccacttc
    12421 agttggtcag cccatcatcc tttatatcgc tgccatgggg aatattgaca attcactggt
    12481 tgaagcggcg cgtgttgatg gtgcaactga gtttcaagtt ttttggaaga ttaaatggcc
    12541 aagccttctt ccaacaactc tttatattgc aatcatcaca acaattaact cattccagtg
    12601 tttcgccttg attcagcttt tgacatctgg tggtccaaac tactcaacaa gtaccttgat
    12661 gtactacctt tacgaaaaag ccttccaatt gacagaatac ggctatgcca acacaattgg
    12721 tgtcttcttg gcagtcatga ttgctatcgt aagctttgtt caatttaaag tacttggaaa
    12781 cgacgtagaa tactaaagaa aggagacagc tatgcaatct acagaaaaaa aaccattaac
    12841 agcctttact gttatttcaa caatcatttt gctcttgttg actgtgctgt tcatctttcc
    12901 attctactgg attttgacag gggcattcaa atcacaacct gatacaattg ttattcctcc
    12961 tcagtggttc cctaaaatgc caaccatgga aaacttccaa caactcatgg tgcagaaccc
    13021 tgccttgcaa tggatgtgga actcagtatt tatctcattg gtaaccatgt tcttagtttg
    13081 tgcaacctca tctctagcag gttatgtatt ggctaaaaaa cgtttctatg gtcaacgcat
    13141 tctatttgct atctttatcg ctgctatggc gcttccaaaa caagttgtcc ttgtaccatt
    13201 ggtacgtatc gtcaacttca tgggaatcca tgatactctc tgggcagtta tcttgccttt
    13261 gattggatgg ccattcggtg tcttcctcat gaaacagttc agtgaaaata tccctacaga
    13321 gttgcttgaa tcagctaaaa tcgacggttg tggtgagatt cgtaccttct ggagtgtagc
    13381 cttcccgatt gtgaaaccag ggtttgcagc ccttgcaatc tttaccttca tcaatacttg
    13441 gaatgactac ttcatgcaat tggtaatgtt gacttcacgt aacaatttga ccatctcact
    13501 tggggttgcg accatgcagg ctgaaatggc aaccaactat ggtttgatta tggcaggagc
    13561 tgcccttgct gctgttccaa tcgtcacagt cttcctagtc ttccaaaaat ccttcacaca
    13621 gggtattact atgggagcgg tcaaaggata atactctgcg aaaatctctt caaactacgt
    13681 cagcttcacc ttgccatact taagtattgc ctgcggttag cttcctagtt tgttcttcaa
    13741 ttttcattga gtataggaaa atcaatctat caagatacag aagtatattt tatagattta
    13801 gagaatatag aggttataag tgtctacaaa atggagggta tgcagttact ttatgaagtt
    13861 ttgtcagaca cttataaact taagaatggt tttagttaac tatcagaaac gaaggaaaga
    13921 gtatgatttt tgacgatttg aaaaacatca ccttttacaa agggattcat cctaatttag
    13981 acaaggctat cgactatctc taccaacatc gtaaggattc tttcgaatta ggaaagtatg
    14041 atattgatgg agataaagtc tttctagttg ttcaggaaaa tgtcctcaat caagctgaaa
    14101 atgatcaatt tgagtatcat aagaactatg cagatttgca tttgctggta gaaggacatg
    14161 aatattcgag ctacggttca cgtatcaaag acgaggcagt agcattcgac gaagcgagtg
    14221 acattggctt tgttcattgt catgaacact acccactctt gttgggttat cacaattttg
    14281 cgattttctt cccaggtgag ccacatcagc caaatggtta tgcaggcatg gaagaaaagg
    14341 ttcgaaaata tctctttaaa attttgattg attaaaaata ggatgaattg tttttttgta
    14401 aagctttgat aatactctac catgaaattg atctttgtga ggtagagaaa tgagaataaa
    14461 atatttaaaa attggtatct tctaagtatg ctgcaagagc tagtttctta gatggacagg
    14521 ggattacagt tgatgagatg gcttggataa ttaggggcat tgtgaatgca ttgattggta
    14581 gatacataaa attaggtact tatgcggcta agtatggtat tagtatggca cgctcgatct
    14641 taagtagggt agctgcaact gcagcagcaa gagtaggatt actgaccaag atttctggat
    14701 ggattttacg agtagctgtg aatgtagctg atgtatatgg taattttgcc aacaatattg
    14761 ctgcagcttg ggatgcatat gataaaattc ctaacaatgg tcgtataaac ttttaaaatg
    14821 cgagaatgaa agcactttgt atttttttat tgaatatgtt agcttggaca gtgcttgcaa
    14881 tgataattcg tggagggcta gatggatttg ataggcatac ttggagtact attttaattg
    14941 cttcgctgtt cggggtatat gattataagc ccatagataa aaatagaaaa aagtccaaaa
    15001 gaaaaaatag atttgttcat ggtagggact tatgaaagct ttactgacaa aaaagaaaac
    15061 agtttacaaa gaaaaatgat ggaggagcaa acatggcaca aaaaggagta agccttatca
    15121 aggcagcatt tgatacagat aactttctca tgcgttttag tgagaaggtc ttggacatcg
    15181 tgacagccaa tcttcttttt gtcgtctctt gtttacccat cgtgacgatt ggagtggcta
    15241 aaatcagcct ctacgagacc atgttcgaag ttaagaagag cagacgggtg cctgttttta
    15301 aaatctatct aagatctttc aagcaaaatc tgaaactagg tcttcagctg ggtttaatgg
    15361 agttaggaat tgtgtttctt accctttcag atctctatct tttctggggt caaacagctc
    15421 tgcccttcca attgctgaaa gccatttgtt taggtattct gatttttctt actatcgtga
    15481 tgctggctag ttaccctatc gcggcacgtt atgacctatc ttggaaagaa attcttcaaa
    15541 aaggattgat gttggctagt tttaactttc cttggttctt cctcatgtta gccattcttg
    15601 tcctcattgt gatggttctt tatctgtccg ccttcagtct actcttaggt ggctcagtct
    15661 tcctactttt tgggtttgga ctattggtct ttatccagac tggattgatg gagaaaattt
    15721 tcgcaaaata ccaataggag ctttatttct gaaactactt tcaaaggctc caaacgctat
    15781 tctataagcg agaaactaaa atctaagtgt ctataagata ttgaaagcct tttcggtaaa
    15841 gtgtatacta aagaagtaaa gaaaaatctg ctttagcaga aaataaaaat aataggagaa
    15901 aatctatgtc agatttgaaa aaatacgaag gtgtcattcc agccttctac gcatgttatg
    15961 atgatcaagg agaagtaagc ccagaacgta cgcgtgcctt ggttcaatac ttcattgata
    16021 aaggtgttca aggtctttat gtcaatggtt cttctggtga atgtatctac caaagcgttg
    16081 aagatcgcaa gttgattttg gaagaagtca tggcggtagc caaaggtaaa ttgaccatta
    16141 ttgcccatgt tgcttgcaat aatactaaag atagtatgga acttgctcgc catgctgaaa
    16201 gcttgggagt agatgctatt gcaacgattc caccaattta tttccgcttg ccagaatact
    16261 cagttgccaa atactggaac gatatcagtt ctgcagctcc aaacacagac tacgtgattt
    16321 acaacattcc tcaattggca ggggttgctt tgactccaag cctttacaca gaaatgttga
    16381 aaaatcctcg tgttatcggt gtgaagaact cttctatgcc agttcaagat atccaaacct
    16441 ttgtcagcct tggtggagaa gaccatatcg tctttaatgg tcctgatgag cagttcctag
    16501 gaggacgcct catgggggct agggctggta tcggtggtac ttatggtgct atgccagaac
    16561 tcttcttgaa actcaatcag ttgattgcgg ataaggacct agaaacagcg cgtgaattgc
    16621 agtatgctat caacgcaatc attggtaaac tcacttctgc tcatggaaat atgtacggtg
    16681 tcatcaaaga agtcttgaaa atcaatgaag gcttgaatat tggatctgtt cgttcaccat
    16741 tgacaccagt gactgaagaa gatcgtccag ttgtagaagc ggctgctgcc ttgattcgtg
    16801 aaaccaagga gcgcttcctc taatctaaaa ggaggtattt atgacatatt acgttgcaat
    16861 tgatatcggt ggaaccaaca tcaagtatgg tttggttgat caagaggggc aacttcttga
    16921 atcgcatgaa atgccaactg aggcgcataa gggtggacct catatcttac aaaagaccaa
    16981 agatatcgta gctagttatt tagaaaaagg cccagtagca ggtgttgcca tatcttctgc
    17041 tgggatggtg gatccggata agggtgagat tttctatgct gggccgcaaa tccctaacta
    17101 cgcaggcacc cagttcaaaa aggaaatcga agaaagcttt actattcctt gtgagattga
    17161 aaatgatgtc aactgtgcag gtcttgctga ggcagtatct ggttcaggca agggagcaag
    17221 tgtgacactt tgcttgacca ttggaaccgg tatcggtggt tgcttgatta tggataggaa
    17281 agtcttccat ggttttagca attcagcctg tgaagtcggg tatatgcata tgcaggatgg
    17341 agcttttcaa gacttggctt ctacaacagc tttagtgaaa tatgtagctg aagcccatgg
    17401 agaagatgtt gatcagtgga atggccgtag aattttcaaa gaagccactg aaggaaacaa
    17461 aatctgcatg gaaggtattg accgtatggt tgactatcta ggaaaaggtc tggcaaatat
    17521 ttgctacgtt gccaatccag aagtggttat tcttggtggt ggtatcatgg ggcaagaggc
    17581 tatcctcaaa cctaagatcc gtacagcctt gaaagaggct ttggtaccaa gtttagcaga
    17641 aaaaacacga ttagaatttg cccatcacca aaatacagca gggatgttgg gtgcatatta
    17701 tcattttaag acaaaacaat cctagtttgg ctcagccaaa ctaggatttt cttacacgtt
    17761 tttgtctacg atagccgttg agttttttat tttcccagta gctattaaag attttttcct
    17821 tgctttcgcg attgatttcc aaaaagtagg cataaatcaa atcgataaag aagagcatag
    17881 gaagttgagc ggatattcgt tggatatagg agggttggct gtgggtggct acaagaacag
    17941 tctctgtata ggtctggcta tctttattgg gaacacttgt aaagagtaca gtctttgccc
    18001 ccatctcctt agcatctaat agactatcta aaatagaagg agttgagcct gaaagtgaga
    18061 agcccagtac tagacaattt tcatccatga tgctggttgt ccaggcaaag ccgtcttggt
    18121 ctgtcaaagc ttcgcagacc acacctagtc gcataaaacg taatttcatt tcacgggcga
    18181 cgaggccaga actccctgtt ccaaagaagt agatacgctc agcatcttcg attagctggg
    18241 caattcgttc tagttggatt tcgtcaatca agtcttgtgt ttgttccctc atattgctat
    18301 aacttctgag gactcgtttg gtcagtggac tgtgcttgga gacttggttg gcttgatttt
    18361 ctgcctgatg ttggtattgg aaaataaatt ctcggtagcc agtaaagcca cactttttag
    18421 caaagcgggt caaagcagct tgagaaatat gtaatttttg ggtgacttgt tgagaagata
    18481 aatcatctgt aatcgtttca gcttgcaaaa aatagcgagc gatttcttgt tctaggtctg
    18541 tcatttcttc aaaatgtgaa tcaatgatag ttgcgatatc tggtttgtcc atagggaaag
    18601 ctcctttaca tgagtcatac tggaagacta gatcagagaa tagtcacact tcattataac
    18661 acataatata aggatagata aataaaaacg catctctgtt ttaaaaacga aaaaatcgaa
    18721 aaagcttctc tcttttccat aattttctac tcaaattgtg gtacaattaa gagtaagatt
    18781 ttaagttaga aatgagactg atttgtatga gaaaatttaa cagccattcg attccgattc
    18841 ggcttaattt attgttttca atcgtcattt tactctttat gaccattatt ggtcgtttgt
    18901 tgtatatgca ggttttgaac aaggattttt acgaaaaaaa gctagcttca gctagtcaga
    18961 ccaagattac aagcagttca gcccgtgggg aaatttatga tgctagtgga aaacctttgg
    19021 tagaaaatac gttaaagcag gttgtttcct ttacgcgtag caataaaatg acggctacag
    19081 acttaaaaga aacagctaaa aagttactga cttatgtgag catcagttct ccaaatttga
    19141 cagaacgcca gctggcggat tactatttgg ctgatcctga aatctataaa aaaatagtgg
    19201 aagctctccc aagtgagaaa cgcttggatt cagatggcaa tcgtctatcc gaatcagaac
    19261 tgtataacaa tgcggtcgat agtgtacaaa cgagtcaact aaactataca gaggatgaaa
    19321 agaaagaaat ctatcttttt agtcagttaa atgctgttgg aaactttgcg acaggaacca
    19381 ttgcgacaga tcctctaaat gattctcagg tggctgttat tgcctctatt tcaaaggaga
    19441 tgcctggcat tagtatttct acttcttggg atagaaaggt tttggaaact tccctttctt
    19501 ctatagttgg gagtgtatcc agtgaaaaag ctggtctccc agcggaagaa gcagaagcct
    19561 atcttaaaaa aggctattct ctaaatgacc gtgtaggaac ctcctatttg gaaaagcaat
    19621 atgaagagac cttacaagga aaacgctcgg taaaagaaat ccatctggat aaatatggca
    19681 atatggaaag cgtggataca attgaggaag gtagtaaggg aaacaatatc aaactgacca
    19741 ttgatttggc tttccaagat agcgtggatg ctttactgaa aagttatttc aattctgagc
    19801 tagaaaatgg tggagccaag tattctgaag gtgtctatgc agtcgccctt aacccaaaaa
    19861 caggtgcggt tttgtctatg tcagggatta aacatgactt gaaaacggga gagttgacgc
    19921 ctgattcctt gggaacggta accaatgtct ttgttccagg ttcggttgtc aaggcggcga
    19981 ccatcagctc aggttgggaa aatggagtct tgtcaggaaa ccagaccttg acagaccagt
    20041 ccattgtctt ccaaggttca gctcccatca attcttggta tactcaggct tacggttcat
    20101 tccctatcac agcggtccaa gctctggagt attcatcaaa tacctatatg gtccaaacag
    20161 ccttaggtct tatggggcaa acctatcaac ccaatatgtt tgtcggcacc agcaatctag
    20221 agtctgctat ggagaaactg cgttcaacct ttggcgaata tggcttgggt actgcgacag
    20281 gaattgacct accagatgaa tctactggat ttgttcccaa agagtatagc tttgctaatt
    20341 acattactaa tgcctttggg cagtttgata actatacgcc gatgcagttg gctcagtatg
    20401 tagcaactat tgcaaataat ggtgttcgtg tggctcctcg tattgttgaa ggcatttatg
    20461 gtaataatga taagggagga ctgggtgact tgattcagca actgcaaccg acagagatga
    20521 ataaggtcaa tatatccgac tccgatatga gcatcttgca ccaaggtttt tatcaggttg
    20581 cccatggtac tagtggattg acaactggac gtgccttttc aaatggtgcc ttggtatcca
    20641 ttagcggaaa aacaggtaca gccgaaagct atgtggcaga tggtcagcaa gcaaccaata
    20701 ccaatgcggt ggcctatgcc ccatctgata atccccaaat cgctgtcgca gtggtctttc
    20761 ctcataatac caatctaaca aatggtgtag gaccttccat tgcgcgtgac attatcaatc
    20821 tgtatcaaaa ataccatcca atgaattaga aaggaaatta tgctttatcc aacacctatt
    20881 gccaagttga ttgacagtta ttctaagtta ccaggtatcg ggattaagac ggctacgcgt
    20941 ctggcctttt atacgattgg gatgtctgct gatgatgtca atgaatttgc aaaaaatctc
    21001 ctttctgcta agagagaatt gacatattgt tctatttgtg gacgtttgac agacgacgat
    21061 ccttgttcta tctgtactga tccgactcgt gaccagacaa caattttagt tcttgaggat
    21121 agtagagatg tggcagccat ggaaaatatc caagaatacc atggactcta tcatgtcctt
    21181 catggcctca tttctcctat gaatggtatc agtccggacg atatcaatct caagagcctt
    21241 atgactcgtc ttatggatag tgaggtttca gaagtgattg tggcgactaa tgctacagcg
    21301 gatggtgaag cgacttccat gtatctttca cgtttgctca agccggctgg tatcaaggtt
    21361 acgcgtctag cacgaggtct cgctgtggga gcggacattg agtatgcgga cgaagtgaca
    21421 ctcttacgag ccattgaaaa tcggacagag ttgtaagtgt aggcaaattt acgaactcca
    21481 ttcatttata aaaaatcaaa gaggctgaaa atcgttccta tcggcctctt tttgtatagt
    21541 gtgatgagta ggctcaggtt caagttttaa aaaaccaagc aaatatgata tactaaagag
    21601 cgagtattct agtagaatta ggacaaataa tatgaaacaa acgattattc ttttatatgg
    21661 tggacggagt gcggaacgcg aagtctctgt cctttcagct gagagtgtca tgcgtgcggt
    21721 cgattacgac cgtttcacag tcaagacttt ctttatcagt cagtcaggtg actttatcaa
    21781 aacacaggaa tttagtcatg ctccggggca agaagaccgt ctcatgacca atgaaaccat
    21841 tgattgggat aagaaagttg caccaagtgc tatctacgaa gaaggtgcag tggtctttcc
    21901 agtccttcac gggccaatgg gagaagatgg ctctgttcaa ggattcttgg aagttttgaa
    21961 aatgccttac gttggttgca acattttgtc atcaagtctt gccatggata aaatcacgac
    22021 taagcgtgtt ctggaatctg ctggtattgc ccaagttcct tatgtggcta tcgttgaagg
    22081 cgatgatgtg actgctaaaa tcgctgaagt ggaagaaaaa ttggcttatc cagtcttcac
    22141 taagccgtca aacatggggt ctagtgtcgg tatttctaag tctgaaaacc aagaagaact
    22201 ccgtcaagcc ttaaaacttg ccttccgata tgacagccgt gtcttggttg agcaaggagt
    22261 gaatgcccgt gaaattgagg ttggcctctt gggtaactac gatgtcaaga gcacgctacc
    22321 aggagaagtt gtcaaggacg ttgcctttta tgactacgat gccaagtata ttgataacaa
    22381 tattactatg gatattcctg ccaaaatcag tgatgatgtg gtggctgtca tgcgtcaaaa
    22441 tgcagaaaca gccttccgtg ccattggtgg ccttggtcta tctcgttgcg atttcttcta
    22501 tacagataag ggagagattt ttctcaacga gctcaatact atgccaggtt tcacccagtg
    22561 gtctatgtac ccactacttt gggacaatat ggggatcagc tacccaaaac taatcgagcg
    22621 tttggttgac cttgccaagg aaagttttga caagcgcgaa gcgcatttga tataaaatga
    22681 aagagagggt agaagccaga accatcactg cacggtgact agagttctcg gacttcagcc
    22741 ctttttaaag gagtagaaat gaaattaaca atccatgaaa ttgcccaagt tgttggagcc
    22801 aaaaatgata tcagtatctt tgaggacacc cagttagaaa aagctgagtt tgatagtcgt
    22861 ttgattggaa ctggagattt atttgtgcca cttaaaggtg cgcgtgatgg ccatgacttt
    22921 attgaaacag cctttgaaaa tggtgcagca gtaaccttgt ctgagaaaga ggtctcaaat
    22981 catccttaca ttctagtaga tgatgttttg acagcctttc aatccttagc atcctactat
    23041 cttgaaaaaa cgactgttga tgtctttgct gttacaggtt caaatggcaa gacaacgact
    23101 aaggatatgt tggcgcattt actgtcaaca agatacaaga cctacaaaac acaaggcaat
    23161 tacaataatg agattggcct tccttacaca gttcttcata tgcctgaagg aacagaaaag
    23221 ttggttttgg agatgggaca ggatcacttg ggcgatattc atctcttgtc tgaattggct
    23281 cgtccaaaaa cagccatcgt gaccttggtt ggagaagccc atttggcctt tttcaaagac
    23341 cgttcagaga ttgctaaggg aaaaatgcaa attgcagacg gaatggcttc aggttccttg
    23401 cttttagcgc cggctgaccc tatcgtagag gactatttgc caactgataa aaaggtggtt
    23461 cgttttgggc aaggggcaga gctggaaatt actgacttgg ttgagcgcaa agatagtctg
    23521 accttcaagg ccaatttctt agagcaagcc cttgatttgc cagtaactgg caagtacaat
    23581 gcgacaaatg ctatgattgc atcctatgtt gccttgcaag aaggagtttc agaggagcaa
    23641 attcgtttgg ccttccaaga tcttgaattg acgcgtaacc gtaccgagtg gaagaaagca
    23701 gccaatggag cagatatcct gtcagatgtt tacaatgcca atccaactgc tatgaaactg
    23761 attttagaga ctttctctgc cattccagcc aatgaaggtg gcaagaaaat tgcagtgttg
    23821 gcggatatga aggagcttgg tgaccagtct gttcaacttc ataatcagat gattttgagc
    23881 ctttctccag atgtgcttga taccgtgatt ttctatggag aaaatattgc tgaattagcc
    23941 caattggcca gtcaaatgtt cccaatcggc cacgtttact acttcaagaa aacagaagac
    24001 caggatcaat ttgaagacct agtcaagcag gtcaaggaaa gccttggagc ccatgaccaa
    24061 atcctgctca aaggctctaa ctctatgaat ctagccaagt tggtagaaag tttagaaaat
    24121 gaagacaagt gattttgtca agtatttgca aagaatgatt gccattacag atactggctt
    24181 aacctttaca aaagatccgt ttgaccgtga gcgctacgaa gacttgcgaa gtctgttatc
    24241 tgaaatgttg aatcaagcat cagaccttga ttccgaagaa gtggcagaag tcttgaagcc
    24301 aacttctgct tatgcgactc cgttaatgga cgtccgtgct tggattgttg aggatgagaa
    24361 gatttgtctg gttaggggac aaggagagga tagttgggct ttgccaggtg gctttggtga
    24421 agtcggctat tctccaacag aaaatattct caaggaaatt gaagaagaaa ccggttttaa
    24481 agccaaagtt gaaagactgc tagctgtttt tgataccaat cgtttccaac tacagagcaa
    24541 acagtataca aagtttgttt ttggatgtaa gcttcttgat ggacaattcc aagaaaatca
    24601 agaaattgct gaccttcaat tttttgccat tgaccaactg ccgaacttat ctgaaaaacg
    24661 cattaccaag gagcaaatag agcttctttg gcaggtttat caaggtcata gggggcaata
    24721 tcttgactaa gaagatgatt atcgtatttc taaatccatt tttaacaact agcatggtat
    24781 aataatatgc aggaaaattt tgaattatga ggaagactag atgaatttat gggatatttt
    24841 ctttacgact caggcaaccg agccgcccaa atttgacctt ttttggtatg ttagcctatt
    24901 tacgctctta gccttaacct tttatacagc ccatcgctat cgtgaaaaga aggtttacca
    24961 acgatttttc caaatcttgc agactgttca gttaatcctt ctttatggtt ggtactgggt
    25021 caatcatatg ccactgtcag aaagcctacc cttttaccat tgccgtatgg ctatgtttgt
    25081 ggtactcttg cttcctggtc aatccaaata taaacaatac tttgcattat tgggaacatt
    25141 tgggacatta gcagcctttg tttatccagt gccagatgct tacccttttc cacatatcac
    25201 cattctatcc tttatctttg gtcatttagc actcttgggg aactctctag tttatctatt
    25261 gagacagtat aatgcgcgat tgctggatgt gaagggaatt tttctcatga cctttgccct
    25321 aaatgccttg atttttgtgg tcaatttggt gacaggtggc gattacggat ttttgacaaa
    25381 accgccattg gttggggatc acggtctagt agctaattat ttacttgttt caattgtgct
    25441 ggtagctact atcagtttga ctaagaaaat cttagaattc tttttagctc aagaagcaga
    25501 aaaaatgatt gcaaaggaag cttaacacag agctttcttt tttgctctta gagagttttt
    25561 acaagcagct tataaaataa gaatttctga atagacaaac tcaaaaaatg gctgggaaat
    25621 ttaggaaaaa agcaagcacg attaaatttt ttgtgttata atattttgtg aatagctatg
    25681 cctatgttta gctatggaat aatacgaagt gcgaaacttg gaagatagag aggaagcgat
    25741 gtaatggcta gagaaggctt ttttacaggt ctagatattg gaacaagctc tgtcaaggtg
    25801 cttgtggccg agcagagaaa tggtgaatta aatgtaattg gcgtgagtaa tgccaaaagt
    25861 aaaggtgtaa aggatggaat tattgttgat attgatgcag cagcaactgc tatcaagtca
    25921 gccatttccc aagcggaaga aaaggcaggc atttcgatta aatcagtgaa tgtcggcttg
    25981 cctggtaatc ttttgcaggt agaaccaact caggggatga ttccagtaac atctgatact
    26041 aaggaaatta cggatcaaga tgttgaaaat gttgtcaaat cagctttgac aaagagtatg
    26101 acacctgacc gtgaagtcat tacctttatt cctgaagaat ttattgtgga tggtttccaa
    26161 gggattcgtg acccacgtgg catgatgggg gttcgccttg aaatgcgtgg tttgctttat
    26221 acaggacctc gtactatctt gcacaatttg cgtaagacgg ttgagcgtgc aggtgttcag
    26281 gttgaaaatg ttatcatttc accactagca atggttcagt ctgttttgaa cgaaggggaa
    26341 cgtgaatttg gtgctacagt gattgatatg ggggcaggtc aaacgactgt cgctacaatc
    26401 cgtaatcaag aactccagtt cacacatatt ctccaagaag gtggagatta tgtaactaaa
    26461 gatatctcca aggttttgaa aacctctcgc aaattagcgg aaggcttgaa actgaattac
    26521 ggggaagcct atccgcctct tgcaagcaaa gaaaccttcc aagtagaggt tattggagaa
    26581 gtagaagcag tcgaagtgac ggaagcctac ttgtcagaaa ttatttctgc acgaatcaag
    26641 cacatccttg aacaaatcaa gcaagaatta gatagaaggc gtctattgga cctccctggt
    26701 ggtattgtct taatcggtgg gaatgccatt ttaccaggta tggttgagct tgctcaggaa
    26761 gtctttggcg tccgtgtcaa gctttatgtt ccaaatcaag ttggtatccg taatccagcc
    26821 tttgcgcatg tgattagttt atcagaattt gcgggtcaat taacagaagt taatcttttg
    26881 gctcagggag cgataaaagg tgagaatgac ttaagtcatc agccaattag ttttggtggg
    26941 atgctgcaaa aaacagctca gtttgtacaa tcaacgcctg ttcaaccagc tcctgctcca
    27001 gaagtagagc cggtggcgcc tacagaacca atggcggatt tccaacaagc ttcacaaaat
    27061 aaaccgaaat tagcagatcg tttccgtgga ttgatcggaa gcatgtttga cgaataaaga
    27121 ggaaaaataa attatgacat tttcatttga tacagctgct gctcaagggg cagtgattaa
    27181 agtaattggt gtcggtggag gtggtggcaa tgccatcaac cgtatggtcg acgaaggtgt
    27241 tacaggcgta gaatttatcg cagcaaacac agatgtacaa gcattgagta gtacaaaagc
    27301 tgagactgtt attcagttgg gacctaaatt gactcgtggt ttgggtgcag gaggtcaacc
    27361 tgaggttggt cgtaaagccg ctgaagaaag cgaagaaaca ctgacggaag ctattagtgg
    27421 tgccgatatg gtcttcatca ctgctggtat gggaggaggc tctggaactg gagctgctcc
    27481 tgttattgct cgtatcgcca aagatttagg tgcgcttaca gttggtgttg taacacgtcc
    27541 ctttggtttt gaaggaagta agcgtggaca atttgctgta gaaggaatca atcaacttcg
    27601 tgagcatgta gacactctat tgattatctc aaacaacaat ttgcttgaaa ttgttgataa
    27661 gaaaacaccg cttttggagg ctcttagcga agcggataac gttcttcgtc aaggtgttca
    27721 agggattacc gatttgatta ccaatccagg attgattaac cttgactttg ccgatgtgaa
    27781 aacggtaatg gcaaacaaag ggaatgctct tatgggtatt ggtatcggta gtggagaaga
    27841 acgtgtggta gaagcggcac gtaaggcaat ctattcacca cttcttgaaa caactattga
    27901 cggtgctgag gatgttatcg tcaacgttac tggtggtctt gacttaacct tgattgaggc
    27961 agaagaggct tcacaaattg tgaaccaggc agcaggtcaa ggagtgaaca tctggctcgg
    28021 tacttcaatt gatgaaagta tgcgtgatga aattcgtgta acagttgttg caacgggtgt
    28081 tcgtcaagac cgcgtagaaa aggttgtggc tccacaagct agatctgcta ctaactaccg
    28141 tgagacagtg aaaccagctc attcacatgg ctttgatcgt cattttgata tggcagaaac
    28201 agttgaattg ccaaaacaaa atccacgtcg tttggaacca actcaggcat ctgcttttgg
    28261 tgattgggat cttcgccgtg aatcgattgt tcgtacaaca gattcagtcg tttctccagt
    28321 cgagcgcttt gaagccccaa tttcacaaga tgaagatgaa ttggatacac ctccattttt
    28381 caaaaatcgt taagtaaatg aatgtaaaag aaaatacaga acttgttttt cgagaagttg
    28441 cagaggctag tctgagtgct catcgagaga gtggttcggt ctctgtcatt gcagttacca
    28501 agtatgtaga tgtaccgaca gcggaagcct tgcttccgct aggtgtccat catatcggtg
    28561 aaaatcgtgt agataagttt ctggaaaaat atgaagcttt aaaagatcga gatgtgactt
    28621 ggcatttgat tggtaccttg caaagacgta aggtgaaaga tgtcattcaa tacgttgatt
    28681 atttccatgc attggactca gtaaagctag caggggaaat tcaaaaaaga agtgaccgag
    28741 tcatcaagtg tttccttcaa gtaaatattt ctaaagaaga aagcaaacac ggtttttcga
    28801 gagaggaact gctggaaatc ttgccagagt tagccagact agataagatt gaatatgttg
    28861 gtttaatgac gatggcacct tttgaggcta gcagtgagca gttgaaagag attttcaagg
    28921 cggcccaaga tttacaaaga gaaattcaag agaaacaaat tccaaatatg cctatgaccg
    28981 agttaagtat gggaatgagt cgtgattata aagaagcgat tcaattcggt tccacttttg
    29041 ttcgtatagg tacatcattt tttaagtagg agagaaccat gtctttaaaa gatagattcg
    29101 atagatttat agattatttt acggaggatg aggattcaag tctcccttat gaaaaaagag
    29161 atgagcctgt gtttacttca gtaaattctt cacaggaacc ggctctccca atgaatcaac
    29221 cttcacagtc ggctggcaca aaagagaaca atatcaccag acttcatgca agacaacagg
    29281 aattggcaaa tcagagtcag cgtgcaacgg ataaggtcat tatagatgtt cgttatccta
    29341 gaaaatatga ggatgcaaca gaaattgttg atttattggc aggaaacgaa agtatcttga
    29401 ttgattttca gtatatgaca gaggtgcagg ctcgtcgttg tttggactat ttggatggag
    29461 cttgtcatgt tttagctgga aatttgaaaa aggtagcttc taccatgtat ttgttgacac
    29521 cagtgaacgt tattgtaaat gttgaagata tccgtttacc agatgaagat caacagggtg
    29581 agttcggttt tgatatgaag cgaaatagag tacgataatg atttttttaa ttcgtatgat
    29641 ttataatgca gtggatattt actccctgat tttggtagcc ttcgctgtca tgtcttggtt
    29701 tccaggtgcc tacgaatcca gtttaggtcg ttggattgta gcgttggtga aaccagtgct
    29761 tgctcccttg caacgcctgc ctttacagat agcgggtctt gatttatctg tttgggttgc
    29821 gattgttttg gttcgatttt taggagaaaa cctagtgcgt tttctggcga tgataggatg
    29881 aataaaggga tttatcagca tttctccata gaagatcgtc catttcttga caagggaatg
    29941 gaatggataa agaaggtaga agatagctat gctccttttt taactccttt tatcaatcct
    30001 catcaggaga agctattaaa gattttggcc aaaacctatg gtcttgcttg tagcagtagt
    30061 ggggaattcg tctcgagtga gtatgttcga gttttattat acccagatta tttccaacca
    30121 gagttttcag attttgaaat atctctccag gaaattgtgt attccaataa atttgaacat
    30181 ttaacgcatg ctaagatttt agggacagtc atcaatcaat tagggattga acggaaactt
    30241 tttggagata tcctagtaga tgaagaacgg gcgcagatta tgattaatca gcagtttctt
    30301 cttctctttc aagatggact aaagaaaatt ggtcgtatac ctgtttcgct ggaggaacgt
    30361 cctttcaccg agaaaataga taagctagaa cagtatcgag aactggattt atctgtgtct
    30421 agttttcgat tagatgttct tttatcaaat gttttgaaac tatctaggaa tcaagcaaac
    30481 cagttgattg aaaagaaact tgtccaagta aattatcatg tggtagacaa atcagattac
    30541 actgttcaag ttggagactt gattagtgtg agaaaatttg gtcgcttgag attacttcaa
    30601 gataagggac aaacgaaaaa agagaagaaa aaaataaccg tccagttatt attaagtaag
    30661 tgaggaatag aatgccaatt acatcattag aaataaagga caagactttt ggaactcgat
    30721 tcagaggttt tgatccagaa gaagtcgatg aatttttaga tattgtggtt cgtgattacg
    30781 aagatcttgt gcgtgcgaat catgataaaa atttgcgtat taagagttta gaagagcgtt
    30841 tgtcttactt tgatgaaata aaagattcat tgagccagtc tgtattgatt gctcaggata
    30901 cagctgagag agtgaaacag gcggcgcatg aacgttcaaa caatatcatt catcaagcag
    30961 agcaagatgc gcaacgcttg ttggaagaag ctaaatataa ggcaaacgag attcttcgtc
    31021 aagcaactga taatgctaag aaagtcgctg ttgaaacaga agaattgaag aacaagagcc
    31081 gtgtcttcca ccaacgtctc aaatctacaa ttgagagtca gttggctatt gttgaatctt
    31141 cagattggga agatattctc cgtccaacag ctacttatct tcaaaccagt gatgaagcct
    31201 ttaaagaagt ggttagcgaa gtacttggag aaccgattcc agctccaatt gaagaagaac
    31261 caattgatat gacacgtcag ttctctcaag cagaaatggc agaattacaa gctcgtattg
    31321 aggtagccga taaagaattg tctgaatttg aagctcagat taaacaggaa gtggaagctc
    31381 caactcctgt agtgagtcct caagttgaag aagagcctct gctcatccag ttggcccaat
    31441 gtatgaagaa ccagaagtag ctccaatgca tccgataggt ccaacaccag ctacagaaac
    31501 tgttgattca ataccgggat ttgaagcacc gcaagaatct gttacaattt tataagaaat
    31561 attctgagaa caatatctta tccttatatt tccagcgagc aggagatggt gtgagtcctg
    31621 taatccctat tgataagatt atcctctcaa aaactcaagt ctgaagctag taagatttga
    31681 cgtttcccac gttacgggat aagagggaga aagactaaat ctttttccga ataaaggtgg
    31741 taccacgatt ttcgtccttt ttggaagtcg tggtttttaa tttgttatta tttataaagg
    31801 agataccatg aaactcaaag acacccttaa tcttgggaaa actgaattcc caatgcgtgc
    31861 aggccttcct accaaagagc cagtttggca aaaggaatgg gaagatgcaa aactttatca
    31921 acgtcgtcaa gaattgaacc aaggaaaacc tcatttcacc ttgcatgatg gccctccata
    31981 cgctaacgga aatatccacg ttggacatgc tatgaacaag atttcaaaag atatcattgt
    32041 tcgttctaag tctatgtcag gattttacgc accatttatt cctggttggg atactcatgg
    32101 tctgccaatc gagcaagtct tgtcaaaaca aggtgtcaaa cgtaaagaaa tggacttggt
    32161 tgagtacttg aaactttgcc gtgagtacgc tctttctcaa gtagataaac aacgtgaaga
    32221 ttttaaacgt ttgggtgttt ctggtgactg ggaaaatcca tatgtgacct tgactcctga
    32281 ctatgaagca gctcaaattc gtgtatttgg tgagatggct aataagggtt atatctaccg
    32341 tggtgctaag ccagtttact ggtcatggtc atctgagtca gcacttgctg aagcagagat
    32401 tgaataccat gacttggttt caacttccct ttactatgcc aacaaggtaa aagatggcaa
    32461 aggagttcta gatacagata cttatatcgt tgtctggaca acgactccat ttaccatcac
    32521 agcttctcgt ggtttgacgg ttggtgcaga tattgattac gttttggttc aacctgctgg
    32581 tgaagctcgt aagtttgtcg ttgctgctga attattgact agcttgtctg agaaatttgg
    32641 ctgggctgat gttcaagttt tggaaactta ccgtggccaa gaactcaacc acatcgtaac
    32701 agaacaccca tgggatacag ctgtagaaga gttggtaatt cttggtgacc acgttacgac
    32761 tgactctggt acaggtattg tccatacagc ccctggtttt ggtgaggacg attacaatgt
    32821 tggtattgct aataatcttg aagtcgcagt gactgttgat gaacgtggta tcatgatgaa
    32881 gaatgctggt cctgaatttg aaggtcaatt ctatgaaaag gtagttccaa ctgttattga
    32941 aaaacttggt aacctccttc ttgcccaaga agaaatctct cactcatatc catttgactg
    33001 gcgtactaag aaaccaatca tctggcgtgc agttccacaa tggtttgcct cagtttctaa
    33061 attccgtcaa gaaatcttgg acgaaattga aaaagtgaaa ttccactcag aatggggtaa
    33121 agtccgtctt tacaatatga tccgtgaccg tggtgactgg gttatctctc gtcaacgtgc
    33181 ttggggtgtt ccacttccta tcttctacgc tgaagatggt acagctatca tggtagctga
    33241 aactattgaa cacgtagctc aactttttga agaatatggt tcaagcattt ggtgggaacg
    33301 tgatgccaaa gacctcttgc cagaaggatt tactcatcca ggttcaccaa acggcgagtt
    33361 caaaaaagaa actgatatca tggacgtttg gtttgactca ggttcatcat ggaatggagt
    33421 ggtggtaaac cgtcctgaat tgacttaccc agccgacctt tacctagaag gttctgacca
    33481 ataccgtggt tggtttaact catcacttat cacatctgtt gccaaccatg gcgtagcacc
    33541 ttacaaacaa atcttgtcac aaggttttgc ccttgatggt aaaggtgaga agatgtctaa
    33601 atctcttgga aatactattg ctccaagcga tgttgaaaaa caattcggtg ctgaaatctt
    33661 gcgtctctgg gtaacaagtg ttgactcaag caatgacgtg cgtatctcta tggatatctt
    33721 gagccaagtt tctgaaactt accgtaagat tcgtaacact cttcgtttct tgattgccaa
    33781 tacatctgac tttaacccag ctcaagatac agtcgcttac gatgagcttc gttcagttga
    33841 taagtacatg acgattcgct ttaaccagct tgtcaagacc attcgtgatg cctatgcaga
    33901 ctttgaattc ttgacgatct acaaggcctt ggtgaacttt atcaacgttg acttgtcagc
    33961 cttctacctt gattttgcca aagatgttgt ttacattgaa ggtgccaaat cactggaacg
    34021 ccgtcaaatg cagactgtct tctatgacat tcttgtcaaa atcaccaaac tcttgacacc
    34081 aatccttcct cacactgcgg aagaaatctg gtcatatctt gagtttgaaa cagaagactt
    34141 cgtccaattg tcagaattac cagaagttca aacttttgct aaccaagaag aaatcttgga
    34201 tacatgggca gccttcatgg actttcgtgg acaagcacaa aaagccttgg aagaagctcg
    34261 taatgcaaaa gttatcggta aatcacttga agcacacttg acagtttatc caaatgaagt
    34321 tgtgaaaact ctactcgaag cagtaaacag caatgtagca caacttttga tcgtgtctga
    34381 gttgaccatc gcagaaggac cagctccgga agctgccctt agcttcgaag atgtagcctt
    34441 cacagttgaa cgtgctactg gtgaagtatg tgaccgttgc cgtcgtatcg acccaacaac
    34501 agcagaacgc agctaccagg cagttatctg tgaccactgt gcaagcatcg tagaagaaaa
    34561 ctttgcggaa gcagtcgcag aaggatttga agagaaataa gattgaaaag tctaggcaaa
    34621 attcaatttg agaagaaaag acaactaatt ttatagtcta ttaaacgcat tgtatcacgt
    34681 ttttgaatac ctgatatgat gcgtttttta tttattttaa aaatttgcga ggtatgactt
    34741 tttatactca acaagaatca aagagaaact tagcaagcta acagtagtaa gataaaatag
    34801 gaatttgata ttagggataa gattggtaaa tagtgtaata tttttacaac aataaattta
    34861 tatagttatt tctggtttct gaaaagtatt atattttatt tcatattata caaattttta
    34921 ttttataata tcagaacata ctttttttaa aagcaaatat gatacaattt tatttgaaaa
    34981 aaataaaaaa ggagatttta ttataaaatt aaaaagactt gctttaatta gtggtatcgt
    35041 cggtcttgtg ggaggaattt tacttcttat tggtcctttt gtcttgttgg gaatagcggt
    35101 aaacacagct gctacaactc ttaatggagg agctactgca ggggcttttt caggtgtagc
    35161 cttactcttg aatgccttga agattgcaaa tcttgttctt ggtatcattg ctattgttta
    35221 ctataaagga gataagcgtg taggtgcagc tccgtctgta ctaatgattg tttctggtgg
    35281 agttagtctc attctattcc gttcttagga tgggttgggg ggatttttgc tattatcgga
    35341 ggatctctat tcctttcaac attgaagaaa ttcaaatcag aagaataaaa ggtattttag
    35401 catgaaaaga acaaaaaagt ttatcggtat aggagtagct ctattatctc tttctcttct
    35461 agttgcatgt ggaacataaa gttcaaagaa tacttcaaca agtaatgatg agaagacagt
    35521 agcaacatcc aatagttcaa aagaaacaat cactttcgat acaccggttg taacagacga
    35581 tgcgattgaa tcaatacgca cttatgcaga ttatatagat ctttataaaa atatttttga
    35641 tgattatttt actaaagctg aggaaggttt caaaggcata gctatggaaa ataatgactc
    35701 gtttactaaa ctaaaagagt caactcaaaa attattcgat gcgcagaaaa aaaggttaaa
    35761 taatgaagat agaatagaaa caaccaaaaa caatgtgatt gccaaacatt gtcaaacagt
    35821 cctttccttt ttggttttga ctagcttttt tgtgaaaaat tgtgtaaaat agaatagata
    35881 aacgagggga aacctcggaa aatttaaagg agaatccatc taatggtaaa attggttttt
    35941 gctcgccacg gtgagtctga atggaacaaa gctaaccttt tcactggttg ggctgatgtt
    36001 gatttgtctg aaaaaggtac acaacaagcg attgacgctg gtaaattgat caaagaagct
    36061 ggtatcgaat ttgaccaagc ttacacttca gtattgaaac gtgctatcaa aacaactaac
    36121 ttggctcttg aagcttctga ccaattgtgg gttccagttg aaaaatcatg gcgcttgaac
    36181 gaacgtcact acggtggttt gactggtaaa aacaaagctg aagctgctga acaatttggt
    36241 gatgagcaag ttcacatctg gcgtcgttca tacgatgtat tgcctccaaa catggaccgt
    36301 gatgatgagc actcagctca cacagaccgt cgttacgctt cacttgacga ctcagttatc
    36361 ccagatgctg aaaacttgaa agtgactttg gaacgtgctc ttccattctg ggaagataaa
    36421 atcgctccag ctcttaaaga tggtaaaaac gtattcgtag gagctcacgg taactcaatc
    36481 cgtgcccttg taaaacacat caaaggtttg tcagatgacg agatcatgga cgtggaaatc
    36541 cctaacttcc caccattggt attcgaattc gacgaaaaat tgaacgtcgt ttctgaatac
    36601 taccttggaa aataaaaaat tgtaagtcta gaattgattt ctaggctttt tatgttagta
    36661 tggaagtatg ataaggaata aaaaacaaga ttatgtactg gcctacaagc aaccagcttc
    36721 aaccacttac atgggttggg aagaagaagc tttaccgata ggcaatggtt ctttaggagc
    36781 aaaagtattt ggccttatag gggctgaacg gattcaattt aatgaaaaaa gtctctggtc
    36841 tggaggtcca cttcctgata gttcagatta tcagggtgga aatcttcagg atcagtatgt
    36901 ttttttagct gagattcggc aggctttgga gaagagagat tacaatctgg ctaaggaact
    36961 ggctgagcag cacctaattg ggccaaaaac gagtcaatat gggacctatc tgtcttttgg
    37021 ggatattcac attgagttca gccagcaagg tacgactttg tctcaggtga cggactatca
    37081 gagacagctg aatattagta aggcacttgc tacgacttct tatgtctata agggaacgcg
    37141 atttgaacgt aaagcttttg cgagttttcc agatgatctc ttggttcaat gttttactaa
    37201 ggaagggttg gaaactctag attttactat agaactatcc ttgacctgtg atttggcttc
    37261 tgatggaaag tatgagcagg aaaaatctga ttacaaggag tgtaagttgg atattactga
    37321 ttctcatatc ttgatgaagg gaagagttaa ggataatgat ctgcggtttg ctagttatct
    37381 agcttgggaa acggatggag atattagagt ttggtcagat agggttcaga tatcaggagc
    37441 cagttatgcc aatctcttct tggccgctaa gacggatttt gcccaaaatc ctgctagcaa
    37501 ttatcgcaag aaactagatt tagagcaaca ggtgatagac ttggtggaca cagctaaaga
    37561 aaagggctat acccaattga aatcaaggca tatcgaggac taccaagcct tattccagcg
    37621 tgttcaattg gatttggaag ctgatgttga cgcatccact acagatgatt tgttaaaaaa
    37681 ttataagcca caagaagggc aggctttgga ggagctgttc ttccagtatg gacggtattt
    37741 attgattagt tcgtccagag actgcccaga tgctctacca gctaacctac agggagtctg
    37801 gaatgcggtc gacaatcctc cttggaattc ggactatcac ttaaatgtca atctgcagct
    37861 gaattattgg ccagcctatg ttaccaatct cctagagacg gtctttccag tcatcaacta
    37921 tgtagatgat ttgcgtgtct atggtcgtct agcggctgta aagtatgcag gaatcgtctc
    37981 tcagaaaggt gaggagaatg gttggttggt tcatactcaa gcgactccct ttggttggac
    38041 ggcacctggt tgggattact attggggttg gtcaccagct gccaatgcgt ggatgatgca
    38101 aaccgtttat gaagcctatt tattttatag ggaccaagac tatctcaggg agaaaattta
    38161 tcccatgttg agggaaacgg ttcgtttttg gaatgccttt ttacataagg atcagcaggc
    38221 gcagcgttgg gtgtcttctc cgtcttattc cccagaacat gggccgattt cgattggcaa
    38281 tacctatgac caatctctga tttggcagtt atttcatgat tttattcagg ctgctcagga
    38341 attgggactg gatgaggact tgttgactga ggttaaggag aagtctgatt tactaaatcc
    38401 tttgcaaatc actcaatctg gtcgaatcag ggagtggtat gaggaggaag agcagtattt
    38461 tcaaaatgag aaagtggagg cccagcatcg gcacgcttcc catctagtgg gactctatcc
    38521 tggcaatctc tttagctaca agggacaaga gtatattgaa gcggcgcgtg ctagcctcaa
    38581 tgatcgtgga gatggcggca caggctggtc caaggctaat aagatcaatc tctgggcgcg
    38641 tttgggagat ggcaatcgag cccataaatt attggcagag cagttaaaga catccacctt
    38701 gcaaaatctt tggtgtagcc atcctccttt tcagatagat ggtaattttg gtgctactag
    38761 tggcatggca gaaatgttac tccagtctca tgcagcttat ctggtacctc tagctgccct
    38821 acctgatgct tggtcaacag gttctgtttc aggcttaatg gcacgtggac attttgaagt
    38881 gagcatgagc tgggaagata aaaaactctt acagttgacc attttatcaa ggagtggagg
    38941 agatttgcga gtttcttatc cagatattga gaagagtgtg attaaaatga atcaagaaaa
    39001 aataaaagcg aaatgcatgg ggaaagattg tatttcggtg gcaacagcag aaggtgatct
    39061 tgttcaattt tatttttaag aagatgttat aaggcagtaa tttgaaactg ccttttaata
    39121 aggatttaag aatataagca gttttcaact agttgaaaaa acgttataat gataatagga
    39181 agtaatactc aatgaaaatc aaagagcaca aactaggaag ctagccgcag gttgctcaaa
    39241 acagtgtttt gaggttgcag atggaagctg acgtggtttg aagagagatt ttcgaggagt
    39301 ataatttgtt tgatagaggg tgggtctgat ggcttatatt gagatgaaac actgttacaa
    39361 gcgttatcag gttggggaca cggagattgt ggccaattgt gatgtgaatt ttgagattga
    39421 aaagggggag ctggttatta tccttggtgc ttcaggtgca ggcaagtcaa cagttcttaa
    39481 ccttcttggg ggaatggata ccaatgatga aggggaaatc tggattgatg gtgttaatat
    39541 tgcggattat agttcccacc agcgcaccaa ttaccgtaga aatgatgtgg ggtttgtttt
    39601 tcagttttat aatctagttt ctaatctgac agctaaggaa aatgtggaac tggcttctga
    39661 aattgtgaca gatgccttga atcctgatca ggccttgaca gatgtaggtc tggctcatcg
    39721 tctcaataac tttccagccc agctttctgg aggggagcaa cagcgagtct ccattgcacg
    39781 cgcggtagcc aaaaatccta aaattctcct ttgtgatgaa ccgactggag ccttggatta
    39841 tcagacgggc aagcaggttt tgaaaattct ccaagacatg tctcgtcaaa agggagcgac
    39901 ggtgatcatc gtgactcata atggagcttt ggcgcccatt gctgatcgcg tgattcaaat
    39961 gcacgatgcc agtgtcaagg atgtggtgct caaccagcat cctcaggata ttgacagttt
    40021 ggagtactag catgatcaag cgaaaaactt attggaagga cttagttcag tccttcacag
    40081 gctccaaggg gcgtttttta tccatcttga tcctgatgat gttgggatct ctagccttag
    40141 taggcctcaa agtaaccagt cccaacatgg aggcgacagc taatgcttat ttaacaactg
    40201 ctcaaacctt ggatttggca gtcatgtcta actatggctt ggatcaagca gaccaagaag
    40261 aactaaaaca gacggagggc gcagaggtcg agtttggcta tttgacagat gtgactatgg
    40321 ataatgggca ggatgccatt cggctgtact ccaaaccaga gcgaatttca acctttcagc
    40381 taagaaaggg acgacttcct cagtcagaca aggaaatcgc tttggccact catttgcaag
    40441 gccaatacag cgtgggacag gagattagtt ttaaagaaaa agaagagggt cattcctctt
    40501 taaaagacca tacttatacc attactggtt ttgtggattc ggctgaaatc ctctcccagc
    40561 gagatatggg ctacgcagga agtggaagtg ggactctgac agcctatggg gtgattttac
    40621 ctagtcaatt tgatcagaaa gtctacaata tagctcgttt gaaatatcaa gatttagcgg
    40681 gtttaaatgc cttttcatca gcttatgaag aaaaatccaa gcaacatcaa gaagagcttg
    40741 aacaaatttt atcagataat ggcaaggtac gtctgcaact tttgaaaaaa gaaggacaag
    40801 agtctctaga caaggggcaa gagacccttg acaaggctca gactaatttg caggaaggca
    40861 agcgtcgttt agcagctgct caagctcgta tacaggctca agaaagtcaa ctagccttgt
    40921 ttcctcaagt tcagagagag caggctagtg ctcaacttac ccaagccaag caggaattgg
    40981 gcaaggaaga ggacaaacta aagcaagctg aacaaaatct agcccaagaa aaggaaaaat
    41041 tagaaaaaca tcagcaagtc ttggatgatt tggcggagcc aaggtatcag gtttataatc
    41101 gtcagaccat gccaggtggt cagggctatc ttatgtatag caatgcttca tccagtattc
    41161 gagcagtggg caatatcttt cctgtggtac tttatgccgt agcagccatg gtgaccttta
    41221 cgaccatgac tcgctttgta gacgaagagc gaactcatgc agggattttt aaggccttgg
    41281 gttatcgtag taaggatatt atcgccaagt ttctccttta tggactagta gctgggactg
    41341 tcggaacggc tctaggtagt atacttggtc attatttgct agccagtgta atttcaagtg
    41401 tcattacaaa aggcatggtg gtgggagaaa ctcagattca gttctattgg acctatagct
    41461 tactagcttt tgtcttgagc ttgttggcga gtgtgttacc agcctatctg gtggcttgga
    41521 gggaacttca tgacgaagca gcccagcttc tacttcctaa acctcctgtc aaaggagcta
    41581 aaatcttatt ggagcgtatc ggttttatct ggcgtcgtct cagttttact cataaggtaa
    41641 cagcccgcaa catctttcgt tataagcaga gaatgttgat gacaatcttt ggtgtggcag
    41701 gttctgtagc tctgctcttt gcaggtttgg gaatccaatc ttctgtagca ggagttccgt
    41761 ctaaacagtt tcaacaaatc caacagtatc agatgcttgt ctctgaaaat cctagtgcga
    41821 ccaatcagga caaggtagag ctagcagaag tgttgaaagg gcaggagata ctagcctacc
    41881 agaaaatcta ttctaaagcg ctatacaagg atttcaaagg caaagctggt cttcaaaaca
    41941 ttactcttat gatgatagag aaggaagatt tgactccctt tatccatctt caacatcatc
    42001 agcaggagct gacattaaaa gatggcatcg ttattacagc taaactcgcc cagctggcag
    42061 gtgtcaaggt tgggcagact ttagaaattg aaggtaagga actaaaggtc gttgctatta
    42121 ctgagaacta cgttggtcac tttatttata tgagtcaggc tagctatgag caactttacg
    42181 gacagctacc ccaagccaac acttatctgg tctcattaag ggataccagt gcaactagta
    42241 tcgaaagtca ggcgggcttg cttatgaatc aatctgcggt gtccagcgtt gtccaaaatg
    42301 cttcagccat tcgactcttc gactctatcg ctagctcact caatcagacc atgaccatct
    42361 tggtcatcgt atcggttcta ttagctattg tcatccttta caatctgacc aatatcaacg
    42421 tagctgagag aatccgtgaa ctctccacta tcaaggttct tggttttcat aataatgaag
    42481 tcaccctcta catttaccgt gagacgattg tgctgtccct tgtgggaatc gtacttggtc
    42541 tgatagctgg tttctattta caccaatttt tgattcaaat gatttcgcct gcgactattc
    42601 tcttttatcc gcaggtaggc tgggaagtct atgtaatccc agtggcagca gtaagcatca
    42661 ttttgacctt gcttggtttc ttcgtcaatt attatctgag aaaggttgat atgttagaag
    42721 ccctgaaatc tgtagagtaa ggtagttatt tttagctgat tgaacttcta tttactaata
    42781 ttcaaaaatc ctccgtttca aagagcaggg aactctttgt gacagaggat tttttctata
    42841 gggctttagc agctgcaatt gcggcttcga agtttggctc agaattgata ttatccacgt
    42901 attcaacgta gcgaatcgta ttgtcagtat cgaggacaaa gactgcgcgt gctaataggt
    42961 gccattcgtt gatcaagagg gcataatcgc gcccgaaaga atggtcaaag tagtctgaaa
    43021 gcataatggc attgtcaagg ccttcagcac cgcaccaacg tttttgagca aaaggtaggt
    43081 ccattgaaac agtcaatacg accgtgttgt ccagtccagc caattcttca ttaaaacgac
    43141 gtgtttgagt tgagcagatg cctgtatcga tagaaggaac gacactcaag acttttttct
    43201 tgccatcaaa atcagccaga gattttttag aaagatctgt tgtagtaaga gaaaaatcaa
    43261 gcgccttgtc gccgacttgt agttgtttac ctgtaaagct cacaggattt ccgagaaaag
    43321 ttaccatagg atactccaat cttttttctt ccattttagc tgaaacagtc ggaattttcc
    43381 aatgatttga ccggaaatat gggcatagaa aaaacgccag ctcatgtgag aatgacgttt
    43441 ttcataggtt tattttgcca atccttcagc aatcttgtca aggttgtatt tcatcatgct
    43501 gtagtagctg tcgccttctt taccttgttc tgcgatagag tcagtaaaga tttgagcgta
    43561 gattgggatg tttgtgtctt gagaaacagt tttcattgga cggtcatcca cacttgattc
    43621 tacaaagagt gatggaactt ttgtttggcg aagtttttca accaaggtct tgatttgttc
    43681 aggagttcct tcttcttcag tattgatttc ccagatgtaa gcacttggga caccataggc
    43741 tttagagaag tatttgaatg ctccttcgct ggttacaatg agtttctttt cagcagggat
    43801 cttattaaat ttatccttac tttctttatc aagtttgtct aacttatcag tatattcttt
    43861 gagatttttt tcatagaatt ctttattgtt agggtctttg gcgctcaatt gtttggcgat
    43921 atttttagca aaaataatac cgttttcaag gttaagccaa gcgtgtgggt cttcttttcc
    43981 tttttcattt tgaccttcaa ggtagataac atcaacgccg tcgctgactg cgaagtagtc
    44041 tttgttttca gttttcttgg cattttctac caattttgta aaccaagcat tgccacctgt
    44101 ttcaaggttg ataccgttat agaaaatcaa attagcctca gaagttttct taacgtcttc
    44161 aggaagtggt tcgtattcgt gtgggtcttg cccaatcgga acgatactat gaaggtcaat
    44221 tttgtcacca gcaatatttt tagtaatatc agcgatgatt gagtttgtag caacaacttt
    44281 tagtttttga ccagaagttg tatctttttt tccgctagca catgctacaa gaatgattgc
    44341 agaaagaaag agaacgagta atgtacctaa ttttttcatt agatcctcca atttattagg
    44401 gctttgcccc ttattttaac aaatgtttat ttttcagttt caaatatcgt tgtttgggag
    44461 cgataaagaa gctaatgaga aagaaactag cagctgtaag cacgatacta gaacctgccg
    44521 caacattaaa actatagcca ataaagagtc ccaaaactga agcagtagct ccgaaggttg
    44581 aggaaaggaa aatcatactt ttcagactat tagcatacag ataagcagtt gcagctgggg
    44641 taatcagcat ggctacaatc aggatagttc cgacactttg catggctgtc acagacacga
    44701 gagtcaggag taccatgaga aggtagtgat agaaattgac aggcattccc atggctttag
    44761 ccaagagttc atcaaaggaa gttatcaaga gttgcttgaa gaaaatccag attaacaaga
    44821 ggatagctgc ccccacaccc atagtaataa acatatccgt atcttggacg gccaggatat
    44881 taccaaaaag gatatggaaa aggtcagttg aacttttagc gacaccaatc aagatgatac
    44941 cgagggctaa gaaagaagaa aaggtaatgc cgatggcggt atcgcttttg ataatcgagt
    45001 ttcctttgat gtaggtaatg atgatggcag ctagcaatcc aaagacaatg gctccgataa
    45061 agaagtcaag gcccaagatg aaggataggg ctacacctgg taagacagca tgtgaaatgg
    45121 catctcccat gagtgacatc ccgcgtagaa taatgaaaca tcccacagct ccagctacaa
    45181 tcccgacgac aatagctgtt atcaaggcat tttgtaggaa atggaatttt tgcaatccat
    45241 cgataaattc tgcaatcata ggtcacctcc attgaaaaag agttgattac cgtaagcttc
    45301 ttttagattg gtttcggtaa aagtttcttt tgttggacca aaggcaatca cttctcgatt
    45361 gacaagtaag acttgatcga agtagtgggg aatcttgctg aggtcgtggt gaacgatgag
    45421 aaccgtcttc ccagcttttt tcaaatctct cagcgtattc atgatgattt cctcactgac
    45481 agagtcaatc ccagcaaagg gttcatccaa gaggatatag tcggcttcct gcaccaaaca
    45541 tctggcaatc aagacccgct ggaattgacc tccagacagt tgactaattt gacgttcagc
    45601 gtagtcagct aggccgacga tttcaagggc ctcttgcact ttcttccaat gtttagcctt
    45661 taaacttcga aagagaggaa tagagggaaa tagtcctaac gagacgcatt ccttgacctt
    45721 gatgggaaag ttgtagtcga tattgatttt ttgttcgaca taggcaattc ggtgtaagga
    45781 ttttttaact tccttgtcat cgagaaatgc ctgaccttga tgtgggataa ttcccaacat
    45841 accttttaat agtgttgatt tcccagcgcc gtttggacca atgatgccgg taattgttgg
    45901 tccatggagc actagtgaaa tatccttaag tgccaacgtt tctttgtagg agacactgag
    45961 gttttcgata cgtatcataa acttgtattc ctcctgtctc ttaatataca ttaaaaaaaa
    46021 aattaagtca agttaatttt tgaaaaaatt aaaataataa ctgaaaaata gattctaaag
    46081 ataactttca ggataaattt ctaaattata aaacgcatag tatcaagtgt aaaaaacttg
    46141 gaattatgcg ttttatcatg gaaagatttt ttataatagc taaaaaataa tagttaaatg
    46201 gttattaatt gcattcccta gtgatttttg ttaagataaa tgcaaataca aatgaaagcg
    46261 agaacaagat gacacgttat caagatgatt tttatgatgc tatcaatgga gaatggcaac
    46321 agacagctga aatcccagca gataagtctc aaacaggagg ttttgttgat ttagaccagg
    46381 aaattgaaga cctgatgctg gcgacaacag acaagtggtt agcaggtgaa gaagtgcctg
    46441 aggatgctat cttggaaaac tttgtcaaat accaccgcct agttcgtgat tttgacaaga
    46501 gagaagctga cggtatcaca cctgtcttac cactccttaa agaattccaa gaattggaga
    46561 cttttgcgga ttttacagct aaactagcag agtttgagct tgcaggaaaa ccaaacttcc
    46621 ttccttttgg tgtatcgcca gactttatgg atgctagaat caatgttcta tgggctagcg
    46681 ctccaagcac aatcttgcca gatacgacct actatgcaga agaacatcct cagcgcgaag
    46741 agctcttgac tctttggaaa gaaagcagcg caaatctcct caaggcttat gatttctctg
    46801 atgaagaaat tgaagacttg ctagaaaaaa gacttgaatt ggaccgccga gttgcggcag
    46861 tggtgctctc taatgaagaa agttcagaat atgctaaact ctatcatcca tattcttacg
    46921 aagatttcaa gaaattcgcg cctgccctac ctttggatga cttcttcaaa gcagttattg
    46981 ggcaattacc agacaaggtt attgtagacg aggaacgttt ctggcaagca gcagagcaat
    47041 tctacagtga ggaagcctgg tctctcctta aagcaacctt gattttgagt gttgtcaatc
    47101 tttcaaccag ctatttaaca gaggatatcc gtgttttgtc tggtgcctac agccgtgccc
    47161 tttctggagt tccagaggca aaagataagg tcaaagcagc ttatcatcta gcacaagaac
    47221 ctttcaagca agccctgggt ctttggtacg cccgtgagaa gttctctcca gaagccaagg
    47281 cggatgtgga gaaaaaagtg gcaaccatga ttgatgttta taaggagcgt ctgcttaaga
    47341 atgactggct cactccagaa acctgtaaac aggctatcgt gaagctcaat gtgatcaaac
    47401 cttatattgg ctatccagaa gaattgcctg cacgttacaa ggataaggta gtgaatgaaa
    47461 ctgccagtct ttttgagaat gctctagcct ttgcgcgtgt ggaaatcaag cacagttgga
    47521 gtaagtggaa ccagcctgta gattataagg aatggggcat gcctgctcat atggtcaatg
    47581 cctactacaa tcctcagaag aacctgattg tctttccagc ggccatttta caggcgcctt
    47641 tctatgactt gcatcagtca tcttctgcta actacggtgg tattggggca gtgattgccc
    47701 atgaaatttc ccacgccttt gatactaacg gggcttcctt tgacgaaaat ggtagcctca
    47761 aggattggtg gacagagagc gactatgctg ccttcaagga gaaaacacaa aaagtcattg
    47821 accaatttga tggacaggat tcttatggag caaccattaa cggtaaattg actgtatcag
    47881 aaaacgtggc tgacttggga ggaatcgcag cagcgcttga agcagctaag agagaagcag
    47941 acttctcagc agaagagttc ttctacaact tcggtcgcat ctggcgcatg aaaggtcgac
    48001 cagaatttat gaaacttttg gctagcgtcg atgtgcacgc accagccaaa ctccgtgtca
    48061 atgtgcaagt accaaacttc gacgatttct ttacaaccta tgatgtcaaa gaaggagacg
    48121 gaatgtggcg ttcaccagag gagcgcgtga ttatttggta atgcaaaaaa tctagtcatc
    48181 agaaaaaagg catccaatca tgtgtgaaaa ccttgatagg atgccttttg taatagaaag
    48241 atttgctgga tagtttactt aaatttcgat tgtcatcatc ttgctagaaa aagggattga
    48301 aggccttttc gtgagcgata gtagtagctg gaccatgtcc tggatagaca tcgtagtttg
    48361 gtagggtgaa gagttgggtc tggatactat gaaggagttg ctccatgcta ccagtcggaa
    48421 ggtcggtccg tccgatagtt tcgcggaata gagcatctcc cgtcaagact agatgagcat
    48481 caggaaagac tagggaaaca ccaccgatag agtgccctgg ggtcggtaga accttaaaac
    48541 gaaattcctc tagttggtat tcttcgtgaa agacaaaggt gtgttctgca ggttttgtga
    48601 ccacatctgc catatcatcg tggcgaggga gaccggagag attatcgaca ggagtgtaga
    48661 gccagctggc ttcgctctct gcgatataga caggaggatt gccaaacgtc tcgcgaacca
    48721 agtccagact catgatatgg tcataatggg cgtgggtcaa gagaatagca cagatcggtt
    48781 tgttgatctt ctcgattgtc tgacgaatgg cttcccaatg actaccagga tcgacgacga
    48841 tgaggtgctt ttcgccttct agataatagg tattttcata ggcaacagga ttcacggttt
    48901 tatggatttt catactagct ccaatctcaa agaatgtact aatactcttc gaaaatctct
    48961 tcaaaccgcg tcaactttat ctgcaacctc aaagcagtgc tttgaacagc ctgcggctag
    49021 ctttctagtt tgctctttga ttttcattga gtataaatta agtatagcac agttagggag
    49081 aataggtaag gatttaaaat gaacttaaaa accagcatga ctagatgaag acaggctggt
    49141 tatcaattta tcaatattgg aaaggtgtca attgcccttc ataggttgca taaactccgt
    49201 cattagcttg tttgatagac gtgatgttta gagtgctacc gtagttggct tctcatttgt
    49261 cgctatattc actataagtt atcctactgg gcaggttctg gtcgttagca tagtattgaa
    49321 cgactgtttt ttatagcttt gctggctgaa taggaacagg cagcaaactc ctaacattag
    49381 gagagcaaag atagaaatag cagttttttt cataggtatt ctccttataa actaaaggat
    49441 agaagaaagt atcttgagga tttttatact cttcaaaaat ctcttcaaac cgcgtcaact
    49501 ttatctgcaa cctcaaagcg gtgctttgag taacctgcgg ctagtttcct agtttgctct
    49561 ttgattttca tttagtatta attccaaaat ccagtcaagg taccagtgta tgtgatacga
    49621 gttccaccgt ttatctttcg tatcttcaat ggaattgggg aagtcagaaa gtctttgggt
    49681 tacaatatgg tttccgttct tctatctctc cttctatcac ctaagtttaa aatctaactt
    49741 cgtagtatat tacggaccaa taattcagaa ttatcaagca attttgaatt atttttttct
    49801 tattctgttc caatctagtt ttcatattct taaaaaagtg ataaaatggt aggaagaatt
    49861 ggagagtaga gatgccgaaa gaagtgaatt taacaggcga agaagttgtc gctttaacca
    49921 aagaatattt aacggaagag gatgttcatt ttgtccataa ggccttggtc tatgctgttg
    49981 aatgccacag tggtcaatat cgcaaatcag gcgagcctta tatcattcac cctatccaag
    50041 tggcaggtat tttagctaag ctaaagctgg atgctgtaac agtagcttgt ggattcttgc
    50101 atgatgtggt ggaagataca gatgcgactt tggacgattt ggaaagagag tttggtcctg
    50161 atgtgcggat gattgttgac ggagttacca agcttggcaa ggtcgagtac aaatcgatcg
    50221 aggagcaatt agcggaaaat catcgcaaga tgctcatggc catgtctgag gacatccgcg
    50281 ttattttggt caaactgtct gaccgcttgc acaatatgcg gaccctgaaa catcttcgaa
    50341 aagacaagca ggagcgtatt tccaaagaaa ccatggaaat ctatgccccg cttgcccatc
    50401 gtttggggat ttccagtgtc aaatgggaat tagaagactt gtctttccgt tatctcaatc
    50461 caacggagtt ttacaagatt acccatatga tgaaggaaaa gcgcagggag cgtgaggcct
    50521 tggtggatga ggtagtcaca aaattagagg agtatacgac agaacgtcac ttgaaaggga
    50581 agatttatgg tcgtcccaag catatttact caattttccg caaaatgcag gacaagagaa
    50641 aacggtttga ggaaatctat gatctgattg ctattcgttg tattttagat acccaaagtg
    50701 atgtttatgc catgcttggt tacgtgcatg aattttggaa accgatgcca ggtcgcttca
    50761 aagactatat cgccaaccgc aaggccaatg gttatcagtc tatccatacg actgtttatg
    50821 gaccaaaagg gccgattgaa ttccagattc gaaccaagga aatgcacgag gtggctgagt
    50881 acggggttgc ggctcactgg gcttataaga aaggtataaa ggggcaagtt aacagcaagg
    50941 aatcagctat tggaatgaac tggatcaagg agatgatgga gctccaagac caggctgatg
    51001 atgctaagga atttgtggac tctgttaagg aaaactattt ggctgaggag atttacgttt
    51061 ttaccccaga tggagctgtc cgttcccttc ccaaagattc aggaccgatt gattttgcct
    51121 acgaaatcca taccaaggtc ggtgaaaaag caactggtgc caaggtcaat ggccgcatgg
    51181 ttccactgac aaccaagtta aagacagggg atcaggttga aattatcgcc aacccgaact
    51241 cctttggacc tagccgtgac tggctcaata tggtcaagac tagcaaggcg cgcaataaga
    51301 ttcgccagtt ctttaaaaac caagataagg aattgtctgt caacaagggt cgtgagatgc
    51361 tgatggctca gttccaagaa aatggctatg tggcaaataa atttatggac aagcgccaca
    51421 tggatcaagt tctgcaaaag accagttaca agacagaaga ctccctcttt gcggccattg
    51481 gttttgggga aatcggtgcg attaccgtct ttaaccgtct gactgaaaag gaacgccgtg
    51541 aggaagagcg tgccaaggcc aaagctgagg cagaggagct tgtcaaaggt ggcgaggtca
    51601 aggttgaaaa taaagaaacc ctcaaggtca agcatgaggg gggagtggtt attgaaggtg
    51661 cttctggtct cctagtgcgg attgctaagt gttgtaaccc cgtgcctggt gacgatattg
    51721 ttggctacat taccaagggt cgtggtgtgg ctattcaccg tgtggactgt atgaacctgc
    51781 gtgcccaaga aaactacgag caacgtctcc ttgatgtgga atgggaagac cagtacccta
    51841 gctcaaataa ggagtatatg gcccatatcg atatctacgg tctcaaccgt acaggactgt
    51901 tgaacgatgt actgcaagtt ctttcaaata caaccaagaa tatttcaacg gtcaatgccc
    51961 aaccaaccaa ggatatgaag tttgctaata tccatgtgtc cttcggtatt gccaacctct
    52021 ctacactgac cacggttgtc gataaaatta agagtgtgcc agaagtttac tctgtcaaac
    52081 ggaccaacgg ctagttgtcc tagctcttac tagaaaggct attatgaaaa tcattatcca
    52141 acgggttaaa aaagcccaag tgagtataga aggccagatt cagggaaaaa tcaatcaggg
    52201 acttttattg ctggttggtg ttggaccaga ggaccaagag gaagatttgg actatgctgt
    52261 gagaaaactg gtcaatatgc ggattttttc agacgcagaa ggcaagatga acctgtctgt
    52321 caaagatatt gaaggagaaa tcctctctat ttctcagttt accctctttg cggatactaa
    52381 gagaggcaat cgtccagcct ttacaggggc agctaaacct gatatggcat cagacttcta
    52441 tgatgctttc aatcaaaaat tagcgcaaga agtgcccgtt cagacaggca tctttggagc
    52501 agatatgcag gttgagctgg ttaataatgg acctgttacc attatcctag atactaaaaa
    52561 gagataagaa agaccaagcc cagtcggctt ggtctttctc atctatcata aaatactcca
    52621 aaaagaaatc ggttcttgat atgcttgggg gaagtctctt ttcaggcttt ggcagatgcg
    52681 ataggaaggg atgagatgtc ctaggatgag gagagttccc tgaaggaaaa gtggaatatc
    52741 acttaaagac accaaggaga gaatcatcag gctatcccat aggagaattt gtaaagcaaa
    52801 acgccagaat ctcggtctaa tctgggaata gagttaacta aagtggtcac aaagttggtt
    52861 tgaaagatag gtcaatagca caggatgaaa gaaaatgagc caaccgctat aaatcaaaat
    52921 ccagtcccaa gtaagccccc ttttaaatgt caaaaatgcc agcatgattc catcaatgac
    52981 aaggagttga atggttttga tgaagatgat ttttttcatg ctaaaacctc cttttcttta
    53041 gagacactcc cataaagaga tgtgtttgtc gtaaaagtct ggatagtttt ctcttaggta
    53101 gtcagctgtc atataataaa aagtagaatg gcaagcagtg atgattggca taagagatga
    53161 aaaacgctga gaactaatga aggctaagag aacaaaaaat agaaaatcaa tggtgagaac
    53221 ccctaaatag tagaagcgaa tctttttatt gatttgagga taaatctcag cgaattgatg
    53281 tttgagtcgg acgaccaaga gaaatagcag gagtccttga gcaaggaaga aaattaaacc
    53341 agagagcaag agccactcaa aagatgtctc gagtctagtg ataaaaaatg caaatagtag
    53401 caaatcaata actgcaattg ctataaaatg gattctatag agttttttca tgacaagacc
    53461 tccctctttt atctaacttc attctactcc aaaagaatgg gagttacaac taaaatgata
    53521 aaaatagcag aagggagatt ctcttaagtt ggctagtatt ctttatttga gtttccttct
    53581 attatctaac ttcttcatca ttccagacaa ataaagctcc gattgcattg aggatataaa
    53641 agatgtattt accgatattg gcgaagtttc cttgaatacc agcttttgtc agctgaacga
    53701 aattgtaaat caaccaaaag ccccactgag ttgttagttt taatgcattc aaagcattgg
    53761 caatgaggga cagtgcaaag gcaatagttg ttacgtaggc aaggagattc atcttgcccc
    53821 catatccgat atagttggtc acaaaggcaa agaggaaggc gatgatggaa atgatgatgg
    53881 ccgccaattt tacctgtttt tggctcattt ggttgggtct gccttcttgc gaagcttccc
    53941 acttctttat agcaaaggta taaatgagga aggtgacggg ataggtaatg atggccgcct
    54001 tatttccaag gatataatca atagcaccgg acaaaatggt attaacaata ccaaagtaat
    54061 ttccccattt gcttaatttc cccgtgaaac gagtggacaa catggaaatc ccaacgttgg
    54121 ttacggaaat caatccaaag ggtacaagag ctgtccatga tccccagtct acaaatttat
    54181 cgaggtgtga gttgaggtaa ccagatgcaa tcgcaatccc aacgaccaaa gcaaccccga
    54241 agaggtcaaa ctatttagat gtagcaaaaa tttttagtga ttttttcata ggttaaacta
    54301 cctttctttt tttcaaatat tctcccacca aatgaaagta aaataaaatg atagaaataa
    54361 aaccctgaaa ataaaggttc tataatattt gtagtgg
//
LOCUS       DAVFER010000012        53335 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1105170250
            SAMEA2167659-rid19724873.denovo.012, whole genome shotgun sequence.
ACCESSION   DAVFER010000012 DAVFER010000000
VERSION     DAVFER010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2167659
            Sequence Read Archive: ERR388902
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 53335)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 53335)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928716.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928716.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 04:07:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,118
            CDSs (total)                      :: 2,073
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 120
            CDSs (without protein)            :: 120
            Pseudo Genes (ambiguous residues) :: 0 of 120
            Pseudo Genes (frameshifted)       :: 67 of 120
            Pseudo Genes (incomplete)         :: 47 of 120
            Pseudo Genes (internal stop)      :: 34 of 120
            Pseudo Genes (multiple problems)  :: 23 of 120
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..53335
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2167659-rid19724873.denovo.012"
                     /strain="1105170250"
                     /db_xref="taxon:1313"
     gene            147..1910
                     /gene="aspS"
                     /locus_tag="VU534_000697"
     CDS             147..1910
                     /gene="aspS"
                     /locus_tag="VU534_000697"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HEU1513326.1"
                     /translation="MKRSMYAGRVREEHIGQEITLKGWVGRRRDLGGLIFIDLRDREG
                     IMQLVINPEKVSAEVMATAESLRSEFVIEVTGQVAAREQANDKLPTGAVELNVTALIV
                     LNTAKTTPFEIKDGIEANDDTRLRYRYLDLRRPEMLENLKLRAKVTHSIRNYLDELEF
                     IDVETPFLSKSTPEGARDYLVPSRVNKGHFYALPQSPQITKQLLMNAGFDRYYQIVKC
                     FRDEDLRGDRQPEFTQVDLETSFLTEQEIQDITESLIARVMKETKGIEVTLPFPRMKY
                     DDAMALYGSDKPDTRFDMLLQDLTEVVRGVDFKVFSEAPAVKAIVVTGAADNYSRKDI
                     DKMTEVAKQYGAKGLAWVKVVDGELNGPVAKFLTGIQEELTTALVLEDKDLVLFVADT
                     LEVANATLGALRGRIAKELGLIDNDKFNFLWVVDWPMFEWSEEEGRYMSAHHPFTLPQ
                     EETAHELEGDLAKVRAIAYDIVLNGYELGGGSLRINQKDLQERMFKALGFSTEEANDQ
                     FGFLLEAMDYGFPPHGGLAIGLDRFVMLLAGEENIREVIAFPKNNKATDPMTQAPSTV
                     ALKQLEELSLQVEEDETNKTN"
     gene            1888..2829
                     /locus_tag="VU534_000698"
     CDS             1888..2829
                     /locus_tag="VU534_000698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000806289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEU1513327.1"
                     /translation="MKQTKRIKRWRYYLRRFAYQIKILRVLQSISREKYDEKISASLV
                     YGFLSAVAVNFFFQPGHVYSSGATGLAQIISALSNHWFGFHIPISLSFYAINFPLMVL
                     AWYQIGHKFTVFTFITVSMSSFFIQFVPVATLTEDPIINSLFGGVVMGLGIGFALRNN
                     ISSGGTDIVSLTIRKKTGKNVGSISFLVNGTIMLIAGLTFGWKYALYSMITIFVSSRV
                     TDAVFTKQKRMQAMIVTNHPEKVIEKIHKKLHRGATMIHDAEGTYNHERKAVLITVIT
                     RAEFNEFKQIMTQVDPSSFVSVSENVHILGRFVEIDN"
     gene            complement(2905..2985)
                     /locus_tag="VU534_000699"
                     /pseudo
     CDS             complement(2905..2985)
                     /locus_tag="VU534_000699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(3121..4107)
                     /locus_tag="VU534_000700"
     CDS             complement(3121..4107)
                     /locus_tag="VU534_000700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001145427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEU1513328.1"
                     /translation="MPVTIKDVAKAAGVSPSTVTRVIQNKSTISDETKKRVRKAMKEL
                     NYHPNLNARSLVSSYTQVIGLVLPDDSDAFYQNPFFPSVLRGISQVASENHYAIQIAT
                     GKDEKERLNAISQMVYGKRVDGLIFLYAQEEDPLVKLVAEEQFPFLILGKSLSPFIPL
                     VDNDNVQAGFDATEYFIKKGCKRIAFIGGSKKLFVTKDRLTGYEQALKHYKLTTDNNR
                     IYFADEFLEEKGYKFSKRLFKHDPQIDAIITTDSLLAEGVCNYIAKHQLDVPVLSFDS
                     VNPKLNLAAYVDINSLELGRVSLETILQIINDNKNNKQICYRQLIAHKIIEK"
     gene            complement(4117..4917)
                     /locus_tag="VU534_000701"
     CDS             complement(4117..4917)
                     /locus_tag="VU534_000701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000938258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1189 domain-containing protein"
                     /protein_id="HEU1513329.1"
                     /translation="MLPYPFSYFSSIWGVRKPLSKRFELNWFQLLFTSIFLISLSMVP
                     IAIQNSSQETYPLETFIDNVYEPLTDKVVQDLSEHATIVDGTLTYTGTASQAPSVVIG
                     PSQIKELPKDLQLHFDTNELVISKESKELTRISYRAIQTESFKSKDSLTQAISKDWYQ
                     QNRVYISLFLVLGASFLFGLNFFIVSLGASFLLYITKRSRLFSFNTFKECYHFILNCL
                     GLPTLITLILGLFGQNMTTLITVQNILFVLYLVTIFYKTHFRDPNYHK"
     gene            complement(5170..6012)
                     /locus_tag="VU534_000702"
     CDS             complement(5170..6012)
                     /locus_tag="VU534_000702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001065636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEU1513330.1"
                     /translation="MNNSIKLKRRLTQSLTYLYLIGLSIVIIYPLLITIMSAFKAGNV
                     SAFKLDTNIDLNFDNFKGLFTETLYGTWYLNTLIIALITMAVQTSIIVLAGYAYSRYN
                     FLARKQSLVFFLIIQMVPTMAALTAFFVMALMLNALNHNWFLIFLYVGGGIPMNAWLM
                     KGYFDTVPMSLDESAKLDGAGHFRRFWQIVLPLVRPMVAVQALWAFMGPFGDYILSSF
                     LLREKEYFTVAVGLQTFVNNAKNLKIAYFSAGAILIALPICILFFFLQKNFVSGLTSG
                     GDKG"
     gene            complement(6014..7306)
                     /locus_tag="VU534_000703"
     CDS             complement(6014..7306)
                     /locus_tag="VU534_000703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000414940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEU1513331.1"
                     /translation="MEKQQPSKAALLSIIPGLGQIYNKQKAKGFIFLGVTIVFVLYFL
                     ALATPELSNLITLGDKPGRDNSLFMLIRGAFHLIFVIVYVLFYFSNIKDAHTIAKRIN
                     NGIPVPRTLKDMIKGIYENGFPYLLIIPSYVAMTFAIIFPVIVTLMIAFTNYDFQHLP
                     PNKLLDWVGLTNFTNIWSLSTFRSAFGSVLSWTIIWALAASTLQIVIGIFTAIIANQP
                     FIKGKRIFGVIFLLPWAVPAFITILTFSNMFNDSVGAINTQVLPILAKFLPFLDGALI
                     PWKTDPTWTKIALIMMQGWLGFPYIYVLTLGILQSIPNDLYEAAYIDGANAWQKFRNI
                     TFPMILAVAAPTLISQYTFNFNNFSIMYLFNGGGPGSVGGGAGSTDILISWIYRLTTG
                     TSPQYSMAAAVTLIISIIVISISMIAFKKLHAFDMEDV"
     gene            complement(7417..8688)
                     /locus_tag="VU534_000704"
     CDS             complement(7417..8688)
                     /locus_tag="VU534_000704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000095461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEU1513332.1"
                     /translation="MSSKFMKSAAVLGTATLASLLLVACGSKTADKPADSGSSEVKEL
                     TVYVDEGYKSYIEEVAKAYEKEAGVKVTLKTGDALGGLDKLSLDNQSGNVPDVMMAPY
                     DRVGSLGSDGQLSEVKLSDGAKTDDTTKSLVTAANGKVYGAPAVIESLVMYYNKDLVK
                     DAPKTFADLENLAKDSKYAFAGEDGKTTAFLADWTNFYYTYGLLAGNGAYVFGQNGKD
                     AKDIGLANDGSIVGINYAKSWYEKWPKGMQDTEGAGNLIQTQFQEGKTAAIIDGPWKA
                     QAFKDAKVNYGVATIPTLPNGKEYAAFGGGKAWVIPQAVKNLEASQKFVDFLVATEQQ
                     KVLYDKTNEIPANTEARSYAEGKNDELTTAVIKQFKNTQPLPNISQMSAVWDPAKNML
                     FDAVSGQKDAKTAANDAVTLIKETIKQKFGE"
     gene            9238..10755
                     /gene="malQ"
                     /locus_tag="VU534_000705"
     CDS             9238..10755
                     /gene="malQ"
                     /locus_tag="VU534_000705"
                     /EC_number="2.4.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-alpha-glucanotransferase"
                     /protein_id="HEU1513333.1"
                     /translation="MKKRQSGVLMHISSLPGAYGIGSFGQSAYDFVDFLVRTKQRYWQ
                     ILPLGATSYGDSPYQSFSAFAGNTHFIDLDILVEQGLLEASDLEGVDFGSDASEVDYA
                     KIYYARRPLLEKAVKRFFEVGDVKDFEKFAQDNQSWLELFAEYMAIKEYFDNLAWTEW
                     PDADARARKASALESYREQLADKLVYHRVTQYFFFQQWLKLKAYANDNHIEIVGDMPI
                     YVAEDSSDMWANPHLFKTDVNGKATCIAGCPPDEFSVTGQLWGNPIYDWEAMDKDGYK
                     WWIERLRESFKIYDIVRIDHFRGFESYWEIPAGSDTAAPGEWVKGPGYKLFAAVKEEL
                     GELNIIAEDLGFMTDEVIELRERTGFPGMKILQFAFNPEDESIDSPHLAPANSVMYTG
                     THDNNTVLGWYRNEIDDATREYMARYTNRKEYETVVHAMLRTVFSSVSFMAIATMQDL
                     LELDEAARMNFPSTLGGNWSWRMTEDQLTPAVEEGLLDLTTIYRRINENLVDLKK"
     gene            10781..13039
                     /gene="glgP"
                     /locus_tag="VU534_000706"
     CDS             10781..13039
                     /gene="glgP"
                     /locus_tag="VU534_000706"
                     /EC_number="2.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000950172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen/starch/alpha-glucan family
                     phosphorylase"
                     /protein_id="HEU1513334.1"
                     /translation="MLSLQEFVQNRYNKTIAECSNEELYLALLNYSKLASSQKPVNTG
                     KKKVYYISAEFLIGKLLSNNLINLGLYDDVKKELAAAGKDLIEVEEVELEPSLGNGGL
                     GRLAACFIDSIATLGLNGDGVGLNYHFGLFQQVLKNNQQETIPNAWLTEQNWLVRSSR
                     SYQVPFADFTLTSTLYDIDVTGYETATKNRLRLFDLDSVDSSIIKDGINFDKTDIARN
                     LTLFLYPDDSDRQGELLRIFQQYFMVSNGAQLIIDEAIEKGSNLHDLADYAVVQINDT
                     HPSMVIPELIRLLTARGIDLDEAISIVRSMTAYTNHTILAEALEKWPLEFLQEVVPHL
                     VPIIEELDRRVKAEYKDPAVQIIDESGRVHMAHMDIHYGYSVNGVAALHTEILKNSEL
                     KAFYDLYPEKFNNKTNGITFRRWLMHANPRLSHYLDEILGDGWHHEADELEKLLSYED
                     KAVVKEKLESIKAHNKRKLARHLKEHQGVEINPNSIFDIQIKRLHEYKRQQMNALYVI
                     HKYLDIKAGNIPARPITIFFGGKAAPAYTIAQDIIHLILCMSEVIANDPAVAPHLQVV
                     MVENYNVTAASFLIPACDISEQISLASKEASGTGNMKFMLNGALTLGTMDGANVEIAE
                     LVGEENIYIFGEDSETVIDLYAKAAYKSSEFYAREAIKPLVDFIVSDAVLAAGNKERL
                     ERFYNELINKDWFMTLLDLEDYIKVKEQMLADYEDRDAWLDKVIVNISKAGFFSSDRT
                     IAQYNEDIWHLN"
     gene            complement(14083..14655)
                     /locus_tag="VU534_000707"
     CDS             complement(14083..14655)
                     /locus_tag="VU534_000707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1513335.1"
                     /translation="MNKLMKFISVFLTSIVLIVSAIPSVSAVYASEQVSQIETNMELQ
                     PVTSLTEEQINTLANEIQSFHPDVSQQWIKEVINRQLQGDYTIPPTYSPFRAVWQGIT
                     VNQMGALLDTAIALALGGTTAGLANLIKVKGKHAAKSAIRSAISRYLGSWFVNDVALE
                     FAMNLLSPGTYLAQLWDKNDAIPNNGRINF"
     gene            complement(15454..16302)
                     /locus_tag="VU534_000708"
     CDS             complement(15454..16302)
                     /locus_tag="VU534_000708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HEU1513336.1"
                     /translation="MNTNLKPKLQRFASATAFACPICQENLTLLETNFKCCNRHSFDL
                     AKFGYVNLVPQIKQSANYDKENFQNRQQILEAGFYQAILDAVSDLLASSKTTTTILDI
                     GCGEGFYSRKLQESHSEKTFYAFDISKDSVQIAAKSEPNWAVNWFVGDLARLPIKDAN
                     MDILLDIFSPANYGEFRRVLSKDGILIKVIPTENHLKEIRQRVQDQLTNKEYSNQDIK
                     EHFQEHFTILSSQTASLTKTITAEQLQALLSMTPLLFHVDQSKIDWSKLTEITIEAEI
                     LVGKAF"
     gene            16454..16732
                     /locus_tag="VU534_000709"
     CDS             16454..16732
                     /locus_tag="VU534_000709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003075836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1513337.1"
                     /translation="MLKEVLTVAKVAKKSSLFLGGVAFGTLGLKILASKEAKKGYSKA
                     LAKAYKLKDELDASVSVVKQHGDDVLQDAKYLYEQEKKEEQLDSLIGE"
     gene            16734..18797
                     /locus_tag="VU534_000710"
     CDS             16734..18797
                     /locus_tag="VU534_000710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000008803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HEU1513338.1"
                     /translation="MSFKVLHRGYQHIRLSSSFSLTLDIQDYLRSLARDEKGIESIQF
                     YMDQQHFTLRIKEGFSVLDNAEAFLKRIDKGKVSELMTLPIRREESAYSIVSGAAVKR
                     VLFRSFVPYPIRYIWTCYQALGYIREAYQTLARKELTMEVLDCSAILLSLFMNQSKTA
                     SNIMFMLDLGNHLDQWSLKKTATDLEQSLLAKESDVFLVQGDTVVSIKSSDVQIGDVL
                     ILSQGNEILFDGQVVSGLGMVNESSLTGESFPVEKRESDLVCANTVLETGELRIRVTD
                     NQMNSRILQLIELMKKSEENKKTKQRYFIKMADKVVKYNFLGAGLTYLLTGSFSKAIS
                     FLLVDFSCALKISTPVAYLTVIKEGLNREMVIKDGDVLEKYLEVDTFLFDKTGTITTS
                     YPIVEKVLPFGDYSEEDILRISACLEEHIYHPIANAIVKQAEIEGIEHEEMHGKLQYI
                     ASKGIKSHIDGQPVLIGNYVLMQDEQIHISSEQNALIEEYKSHYNLLFLAYQNELIGM
                     FCIHTPLRKEAKTALDKLKAQGKKLILATGDTLIRTEELVKDLPFDQVYTDLKPDGKF
                     ELVEKLQKAGHTILMVGDGLNDSAALTLSDIGVVMNESADISKQMSDILLLDNRLDFF
                     QELDSLSSSLQTLIKKNIQDTVVVNSSLIGFGLFNWFSPSNLSILHNLTTLRIVLRSL
                     SIKNR"
     gene            complement(18875..20131)
                     /locus_tag="VU534_000711"
     CDS             complement(18875..20131)
                     /locus_tag="VU534_000711"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000546895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HEU1513339.1"
                     /translation="MHIFDELKERGLIFQTTDEEALRKALEEGQVSYYTGYDPTADSL
                     HLGHLVAILTSRRLQLAGHKPYALVGGATGLIGDPSFKDAERSLQTKDTVDGWVKSIQ
                     GQLSRFLDFENGENKAVMVNNYDWFGSISFIDFLRDIGKYFTVNYMMSKESVKKRIET
                     GISYTEFAYQIMQGYDFFVLNQDHNVTLQIGGSDQWGNMTAGTELLRRKADKTGHVIT
                     VPLITDATGKKFGKSEGNAVWLNPEKTSPYEMYQFWMNVMDADAVRFLKIFTFLSLDE
                     IEDIRKQFEAAPHERLAQKVLAREVVTLVHGEEAYKEALNITEQLFAGNIKNLSVKEL
                     KQGLRGVPNYQVQADENNNIVELLVSSGIVNSKRQAREDVQNGAIYVNGDRIQELDYV
                     LSDADKLENELTVIRRGKKKYFVLTY"
     gene            20273..22738
                     /locus_tag="VU534_000712"
     CDS             20273..22738
                     /locus_tag="VU534_000712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEU1513340.1"
                     /translation="MQNQLNELKRKMLEFFQQKQKNKKSARPGKKGSSTKKSKTLDKS
                     VIFPAILLSIKALFNLLFVLGFLGGMLGAGIALGYGVALFDKVRVPQTEELVNQVKDI
                     SSISEITYSDGTVIASIESDLLRTSISSEQISENLKKAIIATEDEHFKEHKGVVPKAV
                     IRATLGKFVGLGSSSGGSTLTQQLIKQQVVGDAPTLARKAAEIVDALALERAMNKDEI
                     LTTYLNVAPFGRNNKGQNIAGARQAAEGIFGVDASQLTVPQAAFLAGLPQSPITYSPY
                     ENTGELKSDEDLEIGLRRAKAVLYSMYRTGALSKDEYSQYKDYDLKQDFLPSGTVTGI
                     SRDYLYFTTLAEAQERMYDYLAQRDNVSAKELKNEATQKFYRDLAAKEIENGGYKITT
                     TIDQKIHSAMQSAVADYGYLLDDGTGRVEVGNVLMDNQTGAILGFVGGRNYQENQNNH
                     AFDTKRSPASTTKPLLAYGIAIDQGLMGSETILSNYPTNFANGNPIMYANSKGTGMMT
                     LGEALNYSWNIPAYWTYRMLREKGVDVKGYMEKMGYEIPEYGIESLPMGGGIEVTVAQ
                     HTNGYQTLANNGVYHQKHVISKIEAADGRVVYEYQDKPVQVYSKATATIMQGLLREVL
                     SSRVTTTFKSNLTSLNPTLANADWIGKTGTTNQDENMWLMLSTPRLTLGGWIGHDDNH
                     SLSRRAGYSNNSNYMAHLVNAIQQASPSIWGNERFALDPSVVKSEVLKSTGQKPEKVS
                     VEGKEVEVTGSTVTSYWANKSGAPATSYRFAIGGSDADYQNAWSSIVGSLPTPSSSSS
                     SSSSSSDSSNSSTTRPSSSRARR"
     gene            22803..23714
                     /locus_tag="VU534_000713"
     CDS             22803..23714
                     /locus_tag="VU534_000713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HEU1513341.1"
                     /translation="MNQYQKKIVNGKIYSLLSGLIWGICGILGEYFFTHYQVSSGWIT
                     SMRLTLAGSLVLIWSAIQLKSQVLDIWRDKKNYLPFLAYAILGIFSVQYFFYLCVEYS
                     NATTATILQFISPVFILFYNRLVYQKRASKSAVFYVLVAMLGVCLMATKGDLSQLSMT
                     PLALITGLLSAMGVMFNVILPQPFAKRYGFVPTVGWGMILAGLFSNVLSPVYQLSFTL
                     DIWSILICLIIAFFGTAFAFFISMKAVSLVSPLVVAVISASEPLSSALLSVLFLGLVV
                     DWSLLLAIALIILPMIFLSIEEAKESR"
     gene            23944..24642
                     /gene="dapD"
                     /locus_tag="VU534_000714"
     CDS             23944..24642
                     /gene="dapD"
                     /locus_tag="VU534_000714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-acetyltransferase"
                     /protein_id="HEU1513342.1"
                     /translation="MTATKMNAQEIIQFIANAEKKTSVKVTFEGQLATAVPSSVVKLG
                     NVLFGDWKDVAPLLEGLVENQDYVVEQDARNSAVPLLDKRAINARIEPGAIIRDQVEI
                     GDNAVIMMGSVINIGAEIGAGTMIDMGAILGGRAIVGKNSHVGAGAVLAGVIEPASAE
                     PVRVGDNVLIGANAVVIEGVQIGSGSVVAAGAIVTQDVPENVVVAGVPARIIKEIDAQ
                     TQQKTALEDALRTL"
     gene            24710..25840
                     /locus_tag="VU534_000715"
     CDS             24710..25840
                     /locus_tag="VU534_000715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyldiaminopimelate deacetylase"
                     /protein_id="HEU1513343.1"
                     /translation="MLDLIQTRRDLHQIPEIGLEEFKTQAYLLDVIEKLTTGKDFVQI
                     RTWRTGILVYLQGSQPERTIGWRTDIDGLPIVEQTGLPFASQHQGRMHACGHDFHMTI
                     ALGCLERALEEQPKNNLLFLFQPAEENEAGGMLMYEDGAFGDWLPDQFYGLHVRPDLK
                     VGQIATNTHTLFAGTCEVKIRFKGKGGHAAFPHEANDALVAASYFVTQVQSVVSRNVN
                     PIEGAVVTFGVFQAGTTNNVITDTAFLHGTIRALTQDMSLLVQKRVKTVAEGVAAAFD
                     MEVEVELKQGGYLPVENNPALARELMDFFDEKDGIELIDIEPAMTGEDFGYLLSKVDG
                     VMFWLGIDSPYALHHPQMSPKEEVLAIGVAAVSSFLKKKAAE"
     gene            25852..26391
                     /locus_tag="VU534_000716"
     CDS             25852..26391
                     /locus_tag="VU534_000716"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HEU1513344.1"
                     /translation="MKSELRKQVLHEMKAISQEQKQAIDQALTERLLQHPFYQEAKVI
                     ATYLSFSHEFQTQELIEQALKDGKKVLIPKTYPKGRMDFVVYDPQQLVKTFFALLELQ
                     GDLEVVDASQIDLIHVPGLAFTTKGYRIGYGGGYYDRYLEHFSGRTLSTIYPCQIQDF
                     IPENHDIPVQEVLIDEGNL"
     gene            26375..27052
                     /locus_tag="VU534_000717"
     CDS             26375..27052
                     /locus_tag="VU534_000717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HEU1513345.1"
                     /translation="MKEIFDRRYPVTSFFLLVTALVFLLMLVTAGGNFDRADTLFRFG
                     AMYGPAIRLFPEQVWRLLSAIFVHIGWEHFIVNMLSLYYLGRQVEEIFGSKQFFFLYL
                     LSGMMGNLFVFVFSPKSLAAGASTSLYGLFAAIIVLRYATRNPYIQQLGQSYLTLFVV
                     NIIGSVLIPGISLAGHIGGAVGGAFLAVIFPVRGEKRMYNTSQRLGAVVLFVGLAILL
                     FYKGMGL"
     gene            27066..27143
                     /locus_tag="VU534_000718"
                     /pseudo
     CDS             27066..27143
                     /locus_tag="VU534_000718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(27353..28282)
                     /locus_tag="VU534_000719"
     CDS             complement(27353..28282)
                     /locus_tag="VU534_000719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000428165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1513346.1"
                     /translation="MENKFVEFIENNKKVIISSVAVGVVLVLGFGWYSYNQQQAEQQA
                     KIVQLEKDSKSDKEQVDKLFESFDASSDESISKLKELSETSLKTDAGKDYLNNKVKES
                     SKAIVDFHLQKGLAYDVKDSDDKFKDKATLETNVKEITKQIDFIKKVDETFKQENLEE
                     TLKSLNDLVDKYQKQIELLKKEEEKAAEKAKESSSQSNSSGSASNESYNGSSNSNVDY
                     SSSEQTNGYSNNYGGQDYSGSGDSSTNGGSSEQYSSSNSNSGANNVYRYKGTGADGYQ
                     RYYYKDHNNGDVYDDDGNYLGNFGGGIAEPSQR"
     gene            complement(28700..29599)
                     /gene="galU"
                     /locus_tag="VU534_000720"
     CDS             complement(28700..29599)
                     /gene="galU"
                     /locus_tag="VU534_000720"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000202216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HEU1513347.1"
                     /translation="MTSKVRKAVIPAAGLGTRFLPATKALAKEMLPIVDKPTIQFIVE
                     EALKSGIEDILVVTGKSKRSIEDHFDSNFELEYNLKEKGKTDLLKLVDKTTDMRLHFI
                     RQTHPRGLGDAVLQAKAFVGNEPFVVMLGDDLMDITDEKAVPLTKQLMDDYERTHAST
                     IAVMPVPHDEVSAYGVIAPQGEGKDGLYSVETFVEKPAPEDAPSDLAIIGRYLLTPEI
                     FEILEKQAPGAGNEIQLTDAIDTLNKTQRVFAREFKGARYDVGDKFGFMKTSIDYALK
                     HPQVKDDLKNYLIQLGKELTEKE"
     gene            complement(29621..30637)
                     /locus_tag="VU534_000721"
     CDS             complement(29621..30637)
                     /locus_tag="VU534_000721"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000415108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HEU1513348.1"
                     /translation="MEKQTVAVLGPGSWGTALSQVLNDNGHEVRIWGNLPEQINEINT
                     HHTNKHYFKDVVLDENIIAYTDLAETLKDVDAILFVVPTKVTRLVAQQVAQTLDHKVI
                     IMHASKGLEPDSHKRLSTILEEEIPEHLRSDIVVVSGPSHAEETIVRDLTLITAASKD
                     LQTAQYVQKLFSNHYFRLYTNTDVIGVETAGALKNIIAVGAGALHGLGFGDNAKAAII
                     ARGLAEITRLGVALGASPLTYSGLSGVGDLIVTGTSIHSRNWRAGDALGRGESLADIE
                     ANMGMVIEGISTTRAAYELAQELGVYMPITQAIYQVIYHGTNIKDAIYDIMNNEFKAE
                     NEWS"
     gene            30849..31230
                     /locus_tag="VU534_000722"
                     /pseudo
     CDS             30849..31230
                     /locus_tag="VU534_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809823.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            complement(31404..31829)
                     /locus_tag="VU534_000723"
     CDS             complement(31404..31829)
                     /locus_tag="VU534_000723"
                     /inference="COORDINATES: protein motif:HMM:NF025080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU1513349.1"
                     /translation="MTNLSSVDSEELFQFYRERGNAENFIKERKAGFFGDKTDSSTMI
                     KNEVRMMMGCLAYNLYLFLKQLAGDEVKSLTIKRFRRLFLHIAGKYVSTARRHILKFS
                     SLYAYSKQFQALFDTICQINLILPVPYRARGQGKTCLTE"
     gene            complement(31897..32547)
                     /gene="phoU"
                     /locus_tag="VU534_000724"
     CDS             complement(31897..32547)
                     /gene="phoU"
                     /locus_tag="VU534_000724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001245788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HEU1513350.1"
                     /translation="MRNQFDLELHELEQSFLGLGQLVLETASKALLALASKDKEMAEL
                     IINKDHAINQGQSAIELTCARLLALQQPQVSDLRFVISIMSSCSDLERMGDHMAGIAK
                     AVLQLKENQLAPDEEQLHQMGKLSLSMLADLLVAFPLHQASKAISIAQKDEQIDQYYY
                     ALSKEIIGLMKDQETSIPNGTQYLYIIGHLERFADYIANICERLVYLETGELVDLN"
     gene            complement(32562..33314)
                     /gene="pstB"
                     /locus_tag="VU534_000725"
     CDS             complement(32562..33314)
                     /gene="pstB"
                     /locus_tag="VU534_000725"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003101281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEU1513351.1"
                     /translation="MGTFSVRHLDLFYGDFQALKNISIQLPERQITALIGPSGCGKST
                     FLKTLNRMNDLVPSCHIEGQVLLDEQDIYSSKFNLNQLRKRVGMVFQQPNPFAMSIYD
                     NVAYGPRTHGIRDKKQLDALVEKSLKGAAIWEEVKDDLKKSAMSLSGGQQQRLCIARA
                     LAVEPDILLMDEPTSALDPISTLKIEDLIQQLKKDYTIIIVTHNMQQASRISDKTAFF
                     LTGEICEFGDTVDVFTNPKDQRTEDYISGRFG"
     gene            complement(33316..34131)
                     /gene="pstA"
                     /locus_tag="VU534_000726"
     CDS             complement(33316..34131)
                     /gene="pstA"
                     /locus_tag="VU534_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HEU1513352.1"
                     /translation="MSKYLLKLLVYCFSALTFGSLFLIIGFILIKGLPHLSLSLFSWT
                     YTSENISLMPAIISTVILVFGALLLALPIGIFAGFYLVEYTKKDSLCVKIMRLASDTL
                     SGIPSIVFGLFGMLFFVVFLGFQYSLLSGILTSVIMVLPVIIRSTEEALLSVSDSMRQ
                     ASYGLGAGKLRTVFRIVLPVAMPGILAGVILAIGRIVGETAALMYTLGTSTNTPSSLM
                     SSGRSLALHMYMLSSEGLHVNEAYATGVILIITVLMINTLSSLLSRKLVKGAS"
     gene            complement(34124..34987)
                     /gene="pstC"
                     /locus_tag="VU534_000727"
     CDS             complement(34124..34987)
                     /gene="pstC"
                     /locus_tag="VU534_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HEU1513353.1"
                     /translation="MTKQAFKEAVFRAIFFMSATVAVVAILLICFFIFSNGLPFIANY
                     GFARFLLGSDWSPTNIPASYGILPMIVGSLLITLGAIVIGVPTGILTSVFMVYYCPKP
                     VYGFLKSAINLMAAIPSIVYGFFGLQLLVPWIRSFLGNGMSVLTASLLLGIMILPTII
                     SLSESAIRTVPKTYYSGSLALGASHERSIFSVILPAARSGILSAVILGIGRAVGETMA
                     VILVAGNQPIIPSGLFSGTRTLTTNIVLEMAYASGQHREALIATSAVLFFLILLINAY
                     FAYLKGKSSYE"
     gene            complement(35105..35980)
                     /locus_tag="VU534_000728"
     CDS             complement(35105..35980)
                     /locus_tag="VU534_000728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate-binding protein"
                     /protein_id="HEU1513354.1"
                     /translation="MKFKKMLTLAAIGLSGFGLVACGNQSAASKQSASGTIEVISREN
                     GSGTRGAFTEITGILKKDGDKKIDNTAKTAVIQNSTEGVLSAVQGNANAIGYISLGSL
                     TKSVKALEIDGVKASRDTVLDGEYPLQRPFNIVWSSNLSKLGQDFISFIHSKQGQQVV
                     TDNKFIEAKTETTEYTSQHLSGKLSVVGSTSVSSLMEKLAEAYKKENPEVTIDITSNG
                     SSAGITAVKEKTADIGMVSRELTPEEGKSLTHDAIALDGIAVVVNNDNKASQVSMAEL
                     ADVFSGKLTTWDKIK"
     gene            complement(36147..37478)
                     /locus_tag="VU534_000729"
     CDS             complement(36147..37478)
                     /locus_tag="VU534_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000833277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component sensor histidine kinase"
                     /protein_id="HEU1513355.1"
                     /translation="MKRYLQFWLVNLSVSLILIAGMALTWISKGIGLFLLALSLGLGG
                     YWLFCLWKWEVAFETLHQPLLTSSEYFLEKGQEDLKSLAQYVSGLKTKVSQQDQQYKD
                     LAETMEVLLSHLTMGTFLVSAQGQMLLSSRSLPHYFPDVDGDISSLDDLKRMDIRNLV
                     HQAFDQKTRLKQEVSGFHEGDLILEVTAVPVFSPTQSVEAVLVLLYDLTTIRTYEKLN
                     LAFVSNASHELRTPVTSIKGFAETIKGMSAEEEALKDDFLDIIYKESLRLEHIVEHLL
                     TLSKAQQMPIQWTTLSLAEFVQDLTQSLQPQLKKKDLQLKVQVPDDVTLVSDSQLLSQ
                     ILLNLLSNAIRYTEQGGKIEVKTQKVNEGIKISVSDTGIGISQLEQDRIFERFYRVNK
                     GRSRQTGGTGLGLAIVKELSQLLGGQVTVTSQLGRGSCFTIFLPNQSFAQD"
     gene            complement(37479..38186)
                     /locus_tag="VU534_000730"
     CDS             complement(37479..38186)
                     /locus_tag="VU534_000730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU1513356.1"
                     /translation="MTKQVLLVDDEEHILKLLDYHLSKEGFSTQLVTNGRKALALAET
                     EPFDFILLDIMLPQLDGMEVCKRLRAKGVKTPIMMVSAKSDEFDKVLALELGADDYLT
                     KPFSPRELLARVKAVLRRTKGEQEGDDSDNIADDSWLFGTLKVYPERHEVYKANKLLS
                     LTPKEFELLLYLMKHPNMTLTRERLLERIWGYDFGQETRLVDVHIGKLREKIEDNPKA
                     PQFIRTIRGYGYKFKEL"
     gene            complement(38270..38755)
                     /locus_tag="VU534_000731"
     CDS             complement(38270..38755)
                     /locus_tag="VU534_000731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HEU1513357.1"
                     /translation="MAPTDKEDLIRTLELAPHIEGGYFRQTKKASDTINLAGKGRALY
                     TSIYFLLEETNPSHFHRLTADEIWYFHAGSPLTVHMITADGHYEAVTLGLDISKGQQL
                     HYCVPKGTIWGSTVDKDDALVSCLVAPGFEFEDFELFERVDLLATYPEHKEMIERLTR
                     Y"
     gene            38741..39298
                     /locus_tag="VU534_000732"
                     /pseudo
     CDS             38741..39298
                     /locus_tag="VU534_000732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(39613..41304)
                     /locus_tag="VU534_000733"
     CDS             complement(39613..41304)
                     /locus_tag="VU534_000733"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HEU1513358.1"
                     /translation="MNTKELIASELSSIIDSLDQEAILKLLETPKNSEMGDIAFPAFS
                     LAKVERKAPQMIAAELAEKMNSQAFEKVVATGPYVNFFLDKSAISAQVLQAVTTEKEH
                     YADQNIGKQENVVIDMSSPNIAKPFSIGHLRSTVIGDSLSHIFQKIGYQTVKVNHLGD
                     WGKQFGMLIVAYKKWGDEEAVKAHPIDELLKLYVRINAEAENDPSLDEEAREWFRKLE
                     NGDEEALALWQWFRDESLVEFNRLYNELKVEFDSYNGEAFYNDKMDAVVDILSEKGLL
                     LESEGAQVVNLEKYGIEHPALIKKSDGATLYITRDLAAALYRKNEYQFAKSIYVVGQE
                     QSAHFKQLKAVLQEMGYDWSDDITHVPFGLVTKEGKKLSTRKGNVILLEPTVAEAVSR
                     AKVQIEAKNPELENKDQVAHAVGIGAIKFYDLKTDRTNGYDFDLEAMVSFEGETGPYV
                     QYAYARIQSILRKADFKPETAGNYSLNDTESWEIIKLIQDFPRIINRAADNFEPSIIA
                     KFAISLAQSFNKYYAHTRILDESPERDSRLALSYATAVVLKEALRLLGVEAPEKM"
     gene            41440..41886
                     /gene="argR"
                     /locus_tag="VU534_000734"
     CDS             41440..41886
                     /gene="argR"
                     /locus_tag="VU534_000734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEU1513359.1"
                     /translation="MRKRDRHQLIKKMITEEKLSTQKEIQDRLEAHNVCVTQTTLSRD
                     LREIGLTKVKKNDMVYYVLVNETEKIDLVEFLSHHLEGVARAEFTLVLHTKLGEASVL
                     ANIVDVNKDEWILGTVAGANTLLVICRDQHVAKLMEDRLLDLMKDK"
     gene            41937..44471
                     /gene="mutS"
                     /locus_tag="VU534_000735"
     CDS             41937..44471
                     /gene="mutS"
                     /locus_tag="VU534_000735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HEU1513360.1"
                     /translation="MAIEKLSPGMQQYVDIKKQYPDAFLLFRMGDFYELFYEDAVNAA
                     QILEISLTSRNKNADNPIPMAGVPYHSAQQYIDVLIEQGYKVAIAEQMEDPKQAVGVV
                     KREVVQVITPGTVVDSSKPDSQNNFLVSIDREGNQFGLAYMDLVTGDFYVTGLLDFTL
                     VCGEIRNLKAREVVLGYDLSEEEEQILSRQMNLVLSYEKESFEDLHLLDLRLATVEQT
                     ASSKLLQYVHRTQMRELNHLKPVIRYEIKDFLQMDYATKASLDLVENARSGKKQGSLF
                     WLLDETKTAMGMRLLRSWIHRPLIDKERIVQRQEVVQVFLDHFFERSDLTDSLKGVYD
                     IERLASRVSFGKTNPKDLLQLATTLSSVPRIRAILEGMEQPTLAYLIAQLDAIPELES
                     LISAAIAPEAPHVITDGGIIRTGFDETLDKYRCVLREGTSWIAEIEAKERENSGISTL
                     KIDYNKKDGYYFHVTNSQLGNVPAHFFRKATLKNSERFGTEELARIEGDMLEAREKSA
                     NLEYEIFMRIREEVGKYIQRLQALAQGIATVDVLQSLAVVAETQHLIRPEFGDDSQID
                     IRKGRHAVVEKVMGAQTYIPNTIQMAEDTSIQLVTGPNMSGKSTYMRQLAMTAVMAQL
                     GSYVPAESAHLPIFDAIFTRIGAADDLVSGQSTFMVEMMEANNAISHATKNSLILFDE
                     LGRGTATYDGMALAQSIIEYIHEHIGAKTLFATHYHELTSLESSLQHLVNVHVATLEQ
                     DGQVTFLHKIEPGPADKSYGIHVAKIAGLPADLLARADKILTQLENQGTESPPPMRQT
                     SAVTEQISLFDRAEEHPILAELAKLDVYNMTPMQVMNVLVELKQKL"
     gene            44618..46312
                     /gene="patA"
                     /locus_tag="VU534_000736"
     CDS             44618..46312
                     /gene="patA"
                     /locus_tag="VU534_000736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000908145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit PatA"
                     /protein_id="HEU1513361.1"
                     /translation="MLIQKIKTYKWQALASLLMTGLMVASSLLQPRYLQEVLGALLTG
                     KYEAIYSIGAWLIGVAVVGLVAGGLNVVLAAYIAQGVSSDLREDAFRKIQTFSYADIE
                     QFNAGNLVVRMTNDINQIQNVVMMTFQILFRLPLLFIGSFILAVQTLPSLWWVIVLMV
                     VLIFGLTAVMMGMMGPRFAKFQTLLERINAIAKENLRGVRVVKSFVQEKEQFAKFTEV
                     SDELLGQNLYIGYAFSVVEPFMMLVGYGAVFLSIWLVAGMVQSDPSVVGSIASFVNYL
                     SQIIFTIVMVGFLGNSVSRAMISMRRIREILDAEPAMTFKDIPDEELVGSLSFENVTF
                     TYPMDKEPMLKDVSFTIEPGQMVGVVGATGAGKSTLAQLIPRLFDPQDGAIKIGGKDI
                     REVSEGTLRKTVSIVLQRAILFSGTIADNLRQGKGNATLFEMERAANIAQASEFIHRM
                     EKTFESPVEERGTNFSGGQKQRMSIARGIVSNPRILIFDDSTSALDAKSERLVQEALN
                     KDLKGTTTIIIAQKISSVVHADKILVLNQGRLIGQGTHADLVANNAVYREIYETQK"
     gene            complement(46643..46912)
                     /locus_tag="VU534_000737"
                     /pseudo
     CDS             complement(46643..46912)
                     /locus_tag="VU534_000737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019770457.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            47104..48870
                     /gene="patB"
                     /locus_tag="VU534_000738"
     CDS             47104..48870
                     /gene="patB"
                     /locus_tag="VU534_000738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000859866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit PatB"
                     /protein_id="HEU1513362.1"
                     /translation="MKTVQFFWHYFKVYKFSFVVVILMIVLATFAQALFPVFSGQAVT
                     QLANLVQAYQNGNPELVWQSLSGIMVNLGLLVLVLFISSVIYMCLMTRVIAESTNEMR
                     KGLFGKLAQLTVSFFDRRQDGDILSHFTSDLDNILQAFNESLIQVMSNIVLYIGLILV
                     MFSRNVTLALITIASTPLAFLMLIFIVKMARKYTNLQQKEVGKLNAYMDESISGQKAV
                     IVQGIQEDMMAGFLEQNERVRKATFKGRMFSGILFPVMNGMSLINTAIVIFAGSAVLL
                     NDKSIETSTALGLIVMFAQFSQQYYQPIIQVAASWGSLQLAFTGAERIQEMFDAEEEI
                     RPEKAPTFTKLQESVEISHIVFSYLPDKPILKDVSISAPKGQMTAVVGPTGSGKTTIM
                     NLINRFYDVDAGGIYFDGKDIRGYDLDSLRSKVGIVLQDSVLFSGTIRDNIRFGVPDA
                     SQEMVEVAAKATHIHDYIESLPDKYDTLIDDDQSIFSTGQKQLISIARTLMTDPEVLI
                     LDEATSNVDTVTESKIQHAMEVVVAGRTSFVIAHRLKTILNADQIIVLKDGEVIERGN
                     HHELLKLGGFYSELYHNQFVFE"
     gene            49009..49698
                     /locus_tag="VU534_000739"
     CDS             49009..49698
                     /locus_tag="VU534_000739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HEU1513363.1"
                     /translation="MARTVVGVAANLCPVDAEGKIIHSSVSCRFAEIIRQVGGLPLVI
                     PVGDESVVRDYVEMIDKLILTGGQNVHPQFYGEKKTVESDDYNLVRDEFELALLKEAL
                     RQNKPIMAICRGVQLVNVAFGGTLNQEIEGHWQGLPFGTSHSIETVEGSVVAKLFGKE
                     SQVNSVHRQSIKDLAPNFRVTAIDSRDQTIEAIESIDEHRIIGLQWHPEFLVNEEDGN
                     LELFEYLLNEL"
     gene            49702..49881
                     /locus_tag="VU534_000740"
     CDS             49702..49881
                     /locus_tag="VU534_000740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1513364.1"
                     /translation="MEHLVVLSFIFSKFLECGILRKRLNSDKNWRNSTKKLEKNEGKR
                     YDRKEEILEEEHVTY"
     gene            49868..51217
                     /locus_tag="VU534_000741"
     CDS             49868..51217
                     /locus_tag="VU534_000741"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HEU1513365.1"
                     /translation="MSHIKFDYSKVLDKFVAPHEVEYMQSQVTAADELIRKGTGAGSD
                     FLGWLDLPEKYDREEFDRILKAAEQIKSDSDVLVVIGIGGSYLGAKAAIDFLNHHFAN
                     LQTKEERKAPQILYAGNSISSTYLADLVEYVADKDFSVNVISKSGTTTEPAIAFRVFK
                     ELLVKKYGQEEANKRIYATTDRQKGAVKVEADANGWGTFVVPDDIGGRFSVLTAVGLL
                     SIAASGADIKALMEGANAARKDYTSDKISENEAYQYAAVRNILYRKGYATEILVNYEP
                     SLQYFSEWWKQLAGESEGKDQKGIYPTSANFSTDLHSLGQFIQEGTRIMFETVVRVDK
                     PRKNVLIPTLEEDLDGLGYLQGKDVDFVNKKATDGVLLAHTDGDVPNMYVTLPEQDAF
                     TLGYTIYFFELAIALSGYLNAINPFDQPGVEAYKRNMFALLGKPGFEELSKELNARL"
     gene            51341..52801
                     /locus_tag="VU534_000742"
     CDS             51341..52801
                     /locus_tag="VU534_000742"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HEU1513366.1"
                     /translation="MSKDIRVRYAPSPTGLLHIGNARTALFNYLYARHHGGTFLIRIE
                     DTDRKRHVEDGERSQLENLRWLGMDWDESPESHENYRQSERLDLYQKYIDQLLAEGKA
                     YKSYVTEEELAAERERQEVAGETPRYINEYLGMSEEEKAAYIAEREAAGIIPTVRLAV
                     NESGIYKWHDMVKGDIEFEGGNIGGDWVIQKKDGYPTYNFAVVIDDHDMQISHVIRGD
                     DHIANTPKQLMVYEALGWEAPEFGHMTLIINSETGKKLSKRDTNTLQFIEDYRKKGYL
                     PEAVFNFIALLGWNPGGEDEIFSREEFIKLFDENRLSKSPAAFDQKKLDWMSNDYIKN
                     ADLETIFEMAKPFLEEAGRLTDKAEKLVELYKPQMKSVDEIIPLTDLFFSDFPELTEA
                     EREVMTGETVPTVLEAFKAKLEAMTDDEFVTENIFPQIKAVQKETGIKGKNLFMPIRI
                     AVSGEMHGPELPDTIFLLGREKSIQHIENMLKEISK"
     gene            52815..53249
                     /locus_tag="VU534_000743"
     CDS             52815..53249
                     /locus_tag="VU534_000743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HEU1513367.1"
                     /translation="MDIWEKMYEEAQKLYNPHEVSDFVYANHVVAAVEAGDGQIFTGF
                     CMEGTCGVFHLCAERAALFNMYQFSGQTKVKKVLAFRDKPPYGGSSAMPCGACREFLL
                     ELNAENKDAEFMMDYNIRKTVKVAELIPYWWGKERASKFNER"
BASE COUNT        15697 a        10112 c        11511 g        16015 t
ORIGIN      
        1 gtttgaagag attttcgaag agtattagcg ctaattttta gggctttcac ctgactttta
       61 aagactggca aacttttctg atgattttca tgaagagcct gcgcttttat ggtaaaatag
      121 taacagaata aaagaggaga gaaataatga aacgtagtat gtatgctggt cgtgttcgtg
      181 aggaacacat cggacaagaa ataaccttga aaggatgggt tggccgtcgt cgtgaccttg
      241 gtggtttgat ctttatcgat cttcgtgacc gtgaaggaat catgcagttg gttatcaacc
      301 ctgaaaaagt atctgcagag gttatggcaa cagctgaaag ccttcgtagc gaatttgtta
      361 ttgaggtgac tggtcaggtc gctgcgcgtg agcaagccaa tgataagttg ccaactggtg
      421 cggttgagtt aaacgtgaca gctcttattg tgcttaacac agctaagaca acaccatttg
      481 agattaagga tggcattgag gcaaatgacg atacacgttt gcgttaccgt taccttgacc
      541 ttcgtcgtcc agaaatgttg gaaaatctta aacttcgtgc caaggtgacc cactctatcc
      601 gcaactactt ggatgagttg gagtttatcg acgtggagac accattcctt tctaagtcaa
      661 cgcctgaagg ggcgcgtgat tatttagtgc cgtctcgtgt taataagggg catttttacg
      721 ctcttcctca aagtccacaa atcacgaaac agctcttgat gaatgctggt tttgaccgtt
      781 actaccaaat cgttaaatgt ttccgtgacg aggacttgcg tggagaccgc cagcctgaat
      841 ttactcaggt cgacttggaa acgtccttcc ttactgagca agaaatccaa gatattacag
      901 aaagcttgat cgcgcgcgtg atgaaggaaa caaaaggcat cgaagtaacg ctaccattcc
      961 ctcgtatgaa atacgatgat gctatggctc tttacggttc tgacaagcca gatactcgtt
     1021 ttgacatgtt gcttcaggac ttgacagaag tggtccgagg tgtagacttt aaagtctttt
     1081 cagaagcacc tgctgtaaaa gcgattgtgg tcacaggagc tgcggacaac tattcacgta
     1141 aagacatcga caagatgacg gaagtagcca aacagtatgg tgccaaaggt cttgcttggg
     1201 tcaaggtggt tgatggagaa ttaaacggac cagttgccaa gttcttgact ggtatccaag
     1261 aagaattgac aacagcgctt gttcttgaag ataaggactt ggttctcttt gtggcggata
     1321 cgcttgaagt ggctaatgca acactgggtg cccttcgtgg acgtattgct aaagagcttg
     1381 gcttgattga taatgataag ttcaacttcc tttgggtggt tgactggccg atgtttgaat
     1441 ggtctgaaga agaaggccgc tacatgagcg cccaccatcc tttcacactt ccacaggaag
     1501 agactgctca tgaattagaa ggtgatttgg ctaaggttcg tgccattgct tacgatatcg
     1561 tcttgaacgg ttatgagctt ggtggtggta gccttcgtat caaccaaaaa gaccttcaag
     1621 aacgcatgtt caaggctctt ggtttctcaa ctgaagaagc caatgaccag tttggtttcc
     1681 ttcttgaagc catggactat ggtttcccac cacacggtgg tttggctatc gggcttgacc
     1741 gttttgtcat gttgcttgct ggagaagaaa atatccgtga agtcattgcc tttcctaaga
     1801 acaacaaggc aactgaccca atgacacaag ctccatcaac agtcgctctc aaacaactag
     1861 aggaactcag cttacaagta gaagaagatg aaacaaacaa aacgaattaa gcggtggcgc
     1921 tattatctgc gccgctttgc ttatcagata aaaattttac gtgtcttaca aagtatctct
     1981 cgagaaaagt atgatgagaa gatttcggcc tctctggtct atggtttttt atcagcagta
     2041 gcagttaatt tctttttcca accagggcat gtgtattcga gtggtgcaac aggtctggca
     2101 cagattatct ctgccttgag taatcactgg tttggttttc atattccgat ttcgctaagc
     2161 ttctacgcca ttaacttccc tttgatggtc ttagcttggt atcagattgg ccataagttc
     2221 accgtcttta cctttatcac ggtatctatg agttccttct ttatccagtt tgtccctgtg
     2281 gcaaccttga cagaggatcc cattatcaat tccctttttg ggggtgttgt tatgggtttg
     2341 gggattggtt ttgctcttcg aaacaatatc tccagtggtg ggacggatat cgtcagcctg
     2401 actattcgta agaaaacggg taagaatgtc ggtagtattt ctttcttggt aaatggaact
     2461 atcatgctga tagcaggttt gacctttggt tggaaatacg ctctttattc tatgattacc
     2521 atctttgtct ctagccgtgt gacagacgca gtctttacta agcaaaagcg tatgcaggcc
     2581 atgattgtga caaatcatcc agagaaggta attgaaaaaa tccataaaaa attgcaccgc
     2641 ggagcaacca tgatccacga tgcagaagga acctataatc acgagagaaa ggcagtttta
     2701 atcactgtca ttacacgtgc agagtttaat gaatttaaac agattatgac acaagtggat
     2761 ccaagctcct ttgtctctgt ctcggaaaat gttcatattc taggaagatt tgttgagata
     2821 gataattagt gattaatact cttcgaaaat ctcttcaaac cacgtcagct tcaccttgcc
     2881 gtaggtatgg ttactgactt cgtcagtttc atctacaacc tcaaaacagt gttttgagca
     2941 acctgcggct agcttcctag tttgcacttt gattttcatt gagtataaaa agatcttggg
     3001 aaaagactca atttcagtag aaaaggaagt aaatcttccc acaataaaac gcatagtatc
     3061 aagttttttt aatacctgat agtatgcgtt tttgctttta acgacttttt gcccagtctc
     3121 ttatttttcg ataattttgt gggcgatcaa ttgacggtaa caaatttgtt tattgttttt
     3181 attatcatta ataatctgga gaatagtttc aagggaaaca cgaccaagct ctaaactatt
     3241 gatatcgaca taggctgcca agttgagctt gggattaacc gagtcaaagc tgagaacagg
     3301 gacatccagc tggtgtttgg caatatagtt acaaacacct tcagctagga ggctatcggt
     3361 tgtgatgata gcatcaattt gtggatcgtg cttgaataat cgcttgctaa atttatagcc
     3421 cttttcttcc agaaactcgt cggcaaagta gatgcgattg ttgtcagtgg taagtttgta
     3481 atgtttaagc gcctgttcat agcctgttaa acggtctttg gtcacgaaga gctttttact
     3541 tcctccgata aaggcaatgc gtttgcagcc ttttttgatg aaatattcag tcgcatcaaa
     3601 accagcttga acattgtcgt tgtcgacaag tgggatgaaa ggagatagag atttacctaa
     3661 gataaggaag gggaactgtt cttctgcgac gagttttacg agagggtctt cttcttgggc
     3721 atagagaaaa attagcccat ctacacgctt gccgtagacc atttgtgaaa tagcgttgag
     3781 acgctccttc tcatctttcc ctgttgctat ctgaatggca tagtggtttt cagatgcgac
     3841 ttgagagatg ccacgtagaa ccgatggaaa gaaaggattc tggtagaagg cgtctgagtc
     3901 atcaggaaga actaatccga taacctgagt atagctgctt accaagctac gagcgttgag
     3961 gtttgggtgg tagttgagtt ccttcatagc tttgcgaaca cgtttttttg tttcgtcgct
     4021 aatggttgat ttattttgaa taacacgggt tacggttgaa ggcgaaacac cagcagcctt
     4081 ggccacgtct ttaatcgtaa cgggcataaa aatctcctat ttatggtaat ttggatcacg
     4141 gaaatgtgtt ttataaaaga tagtgaccag atacagaaca aaaagaatat tttgtacagt
     4201 aatcagggtt gtcatatttt ggccaaataa tcccaaaata agtgtaatca gagtcggcaa
     4261 tcctaaacag ttcaagataa aatggtagca ctctttaaag gtattaaatg aaaagaggcg
     4321 tgatcttttg gtgatataaa ggagaaagct agctccaaga gagacgataa agaaattcaa
     4381 accaaagagg aagctcgcac cgagaactag gaagaggctg atatagacac gattttgttg
     4441 gtaccagtct ttagaaattg cttgggtcaa gctgtctttg cttttgaaac tctcagtctg
     4501 aatggctcgg taagagatgc gggtcagttc cttgctttcc ttgctgatga ctagctcatt
     4561 tgtatcgaaa tgcagttgca agtccttagg taattccttg atttgacttg gaccaatcac
     4621 aacagaaggg gcttgactag ctgttccagt ataagttaat gtgccatcga caattgtagc
     4681 atgttcagag agatcctgga caaccttatc tgtcagaggt tcatagacat tatcgataaa
     4741 agtttctagc ggataggtct cctgggagct gttttggata gcaatgggta ccatagacaa
     4801 gctgataagg aagatactgg taaagagaag ttgaaaccag ttgagctcga aacgtttgga
     4861 caggggctta cgaacccccc aaatacttga aaaataggaa aatggatatg gaagcatagg
     4921 tatctttcta aaaggtgttt tctatatgag tattattata tagagaaatg cgctttattt
     4981 caagtctagg agaaaaattg cttgctacaa ggatattatt tacagtgaca attgctaata
     5041 atcaatgaaa atcaaagtgc aaactagcca caggttgctc aaagcacaac tttgaggttg
     5101 gagataaagc tgacgtggtt tgaagagatt ttcgaagagt ataaaatgaa aaagggtggc
     5161 ggggataaat tatcccttgt cgccaccact tgtaagtcct gaaacaaagt tcttttgtag
     5221 gaagaagaag agaatacaga ttggaagggc gatgaggata gcacctgctg agaagtaggc
     5281 aatcttcaag tttttcgcat tgttaacgaa ggtttggaga cctacggcaa cagtaaagta
     5341 ttctttctca cgaagcaaga aactagagag gatgtagtcc ccgaaaggtc ccatgaaggc
     5401 ccagagagct tgtacggcaa ccattgggcg aacaagtggt agaacaattt gccagaagcg
     5461 gcggaagtgt cctgcaccgt ctagttttgc agattcgtct aaagacattg gcactgtatc
     5521 gaagtagcct ttcatgagcc aagcattcat cgggatacca ccaccaacgt agaggaagat
     5581 gaggaaccag ttgtggttaa gggcgttcaa cataagcgcc ataacgaaga aggctgtcaa
     5641 agcggccata gttggcacca tttggatgat caagaagaag accaaacttt gtttacgagc
     5701 caagaagttg taacggctgt aagcataacc agcaagtacg atgatacttg tttgaacagc
     5761 catggtaatt aaggcgataa tcaaagtgtt gaggtaccaa gtaccgtaca aggtttcagt
     5821 gaagaggcct ttaaagttat caaaattgag gtcgatatta gtatctagtt taaaggctga
     5881 gacgttacct gctttaaagg ctgacataat ggtaatcaac agtggataga taattacaat
     5941 tgatagacca atcaggtaaa ggtaagtaag gctttgagtc agtctacgtt tgagtttaat
     6001 tgagttattc atcttagacg tcctccatat caaatgcgtg tagtttcttg aatgcgatca
     6061 tagagattga gatgacaatg atagagataa tcaaggtaac agctgccgcc attgagtatt
     6121 gaggagatgt acctgttgtc aaacggtaga tccatgagat caagatatcg gttgaaccag
     6181 ctccacctcc gacactacca ggtcctccac cattgaagag gtacatgata gagaagttgt
     6241 taaagttgaa ggtgtattgg ctaatcaaag taggtgccgc aacagccaaa atcattggga
     6301 aagtgatgtt gcggaatttt tgccaagcgt tggcaccgtc aatataagct gcttcgtaaa
     6361 ggtcgttagg aatagattgc aagataccca aggtcagaac gtagatgtat gggaatccga
     6421 gccaaccttg catcataatc aaggcaatct tagtccaagt tgggtctgtt ttccaaggaa
     6481 taagagctcc atcaaggaaa ggaaggaatt tagccaagat tggcaatact tgagtgttga
     6541 tagcaccgac actatcgtta aacatgtttg agaatgtcaa gatagtgatg aaggctggga
     6601 cagcccaagg aagaaggaaa ataacaccaa agatacgttt tcctttgata aatggttggt
     6661 tggcaatgat agctgtgaag ataccaatta cgatttgtaa agtagaagct gccaaagccc
     6721 aaatgatagt ccaagaaaga acagaaccaa aggcagaacg gaaggtactc aagctccaaa
     6781 tgtttgtaaa gttggtcaaa ccaacccagt ccaacaactt gtttggtggc aagtgttgga
     6841 agtcgtagtt ggtaaaggcg atcatcaagg ttacgataac tgggaagata atcgcgaagg
     6901 tcatggcaac ataagatgga atgatcaaga ggtaagggaa gccattttca taaatccctt
     6961 tgatcatgtc tttgagtgtg cgtggaactg gaattccatt gttaatgcgt tttgcaatcg
     7021 tatgtgcatc tttgatattt gagaaataaa agagtacata aacgattaca aagattagat
     7081 ggaaggcacc acgaatcagc ataaagaggg aattatcacg acctggtttg tcaccaagag
     7141 tgatgaggtt gctcaattca ggggttgcaa gtgctaggaa gtaaaggaca aatacgatgg
     7201 ttacaccaag gaagataaaa cctttggctt tttgtttatt gtaaatctgt cctaacccag
     7261 gaatgataga cagcagggct gctttactag gttgttgctt ttccatatta actcctttca
     7321 taggatacta cttttttata agaaagctaa attatttgtg tctctattga taaattcaaa
     7381 gggggatttg atttccaccc cccttgaaca aattttttat tcaccaaatt tttgtttgat
     7441 tgtttctttg atcaatgtta cagcatcgtt agcagctgtt ttagcatctt tttgaccact
     7501 tacagcatca aagagcatat ttttcgctgg atcccaaact gcagacattt gagagatgtt
     7561 tggcagtggt tgagtgttct tgaactgttt gataacagct gttgtcaact catcgttttt
     7621 accttcagcg tatgaacgag cctcagtatt agctgggatt tcgttagtct tatcatataa
     7681 tactttttgt tgttcagttg caacaaggaa gtctacaaat ttttgagaag cttcaaggtt
     7741 cttaacggct tgaggaatga cccaagcttt accaccaccg aatgcagcat attcttttcc
     7801 atttggaaga gttgggatag ttgcaactcc gtagtttact ttagcatctt taaaggcttg
     7861 agctttccaa ggtccgtcga tgatagcagc tgttttacct tcttggaatt gagtttggat
     7921 taagtttcca gcaccttctg tatcttgcat acctttaggc catttttcgt accaagattt
     7981 agcgtagttg atacctacga tagaaccgtc gtttgcaaga ccgatgtctt tagcgtcttt
     8041 accgttttgg ccaaagacgt aagcaccgtt accggcaaga agtccatatg tatagtagaa
     8101 gtttgtccag tcagctagga aggcagtagt tttaccatct tcaccagcga atgcgtattt
     8161 gctatcttta gcaaggtttt ccaagtcagc aaatgttttt ggagcatctt tcaccaagtc
     8221 tttgttgtag tacataacaa gtgactcgat aacggcagga gcaccgtaaa ctttaccatt
     8281 agcagctgtt acaagagatt tagttgtgtc gtctgtttta gcaccatcgc tcaatttcac
     8341 ttctgaaagt tgtccgtcag aaccaaggct acctacacgg tcgtatggag ccatcataac
     8401 atcagggaca ttaccagatt ggttgtcaag agaaagttta tcaagacctc ctagagcatc
     8461 accagtttta agagtgactt ttactccagc ttctttttca taagctttag caacctcttc
     8521 aatatagctc ttatatccct cgtctacata tacagtgagt tctttgactt cagatgaacc
     8581 agaatcagca ggcttatcag cagttttgct tccgcaagct accaaaagca agctagcaag
     8641 tgtagcagtt ccaagcaccg cagcgctctt cataaattta gatgacatag tgtattcctc
     8701 ctaaagaata gcaagtttta ttgataagga aacgcaaacg ttttccttta tgagcttagt
     8761 atagcacaaa tagaaaacgg ttgcaagtat tttttgtaaa aattttaaaa aatttttaag
     8821 cttgatttga tagcataatt ttgcatttta atagaagaaa agtatgaaat agataagaat
     8881 acagtatttt taataaaaat atatgaaatc tgtctaaaga gggaaatcag gaggggctac
     8941 cttcctattt ctaatctata tctattttct atagacgttt gtgctttgtt gcatataaat
     9001 tcaagctccc taaggaggtt ttgtactttg tatactgtct cgtgagagtc aaactttagg
     9061 attagatagt tttaagttat ctttgctaaa atgagttagt ctccttaaaa ataatcaaaa
     9121 aagtttttta aaaacgcttg caattatgct tgaaaaggag tatacttata agtaacgcaa
     9181 acgtttgcgt ctgaaaaata cgcaacgttc cattatttta acacacgagg tgctattatg
     9241 aaaaaacgtc aaagtggtgt gttgatgcac atctcttctc ttccaggagc ttacggaatc
     9301 ggatcatttg gtcaaagtgc ttacgacttc gttgatttct tggtccgtac aaaacaacgt
     9361 tactggcaaa tccttccatt aggagcaact agttacgggg attctcctta ccaatctttc
     9421 tcagccttcg caggaaacac tcattttatc gatttagata tcttggtgga gcaaggtttg
     9481 ttggaagcaa gtgaccttga aggagttgac tttggtagcg atgcgtctga agttgactat
     9541 gctaaaatct actatgcacg tcgtcctctt ttagaaaaag cggtgaaacg tttctttgaa
     9601 gtcggagatg ttaaagattt tgagaaattt gctcaagaca accaatcatg gcttgagctc
     9661 tttgctgagt atatggctat caaagagtat tttgacaatc ttgcttggac tgaatggcca
     9721 gatgcagatg ctcgtgctcg taaagcttca gcacttgaaa gctatcgtga gcaattggca
     9781 gacaagttgg tttaccaccg tgtgactcaa tacttcttct tccaacaatg gttgaaattg
     9841 aaagcttacg ctaacgacaa ccacatcgaa atcgttgggg acatgccaat ctacgtagcg
     9901 gaagattcaa gtgatatgtg ggcaaatcca catctcttca aaacagatgt caatggtaag
     9961 gctacttgta tcgcaggatg cccaccagat gagttttctg taactggtca gctttggggt
    10021 aatccaatct atgactggga agcaatggac aaagacggct acaaatggtg gattgaacgc
    10081 ttgcgtgaaa gcttcaaaat ctacgatatc gttcgtatcg accacttccg tggcttcgaa
    10141 tcttactggg aaatccctgc tggttccgat acagcagcac ctggtgagtg ggtgaaaggt
    10201 ccaggttaca agctttttgc agccgttaag gaagaacttg gtgagctaaa catcatcgca
    10261 gaagaccttg gcttcatgac agatgaagtg atcgaattgc gtgaacgtac tggcttccca
    10321 ggaatgaaga ttcttcaatt tgccttcaac ccagaagacg aaagcattga tagcccacac
    10381 ttggcacctg ctaactcagt tatgtacaca ggaacacacg ataacaatac ggttcttggt
    10441 tggtaccgta atgagattga tgatgcgact cgtgagtaca tggctcgtta cacgaaccgt
    10501 aaagaatacg aaacagtggt acacgctatg cttcgtacag tattttcatc agttagcttt
    10561 atggcaattg caactatgca agatttacta gaattggatg aggcagctcg tatgaacttc
    10621 ccatctaccc ttggtggaaa ctggtcttgg cgtatgactg aagatcaatt gacaccagct
    10681 gtcgaggaag gtttgcttga cttgacaaca atttatcgcc gaattaatga aaatttggta
    10741 gatttaaaga aataagacaa taatcaggag acaactaaac atgttatcac tacaagaatt
    10801 tgtacaaaat cgttacaata aaaccattgc agaatgtagc aatgaagagc tttaccttgc
    10861 tcttcttaac tacagcaagc ttgcaagcag ccaaaaacca gtcaacactg gtaagaaaaa
    10921 agtttactac atctcagctg agttcttgat tggtaaactc ttgtcaaaca acttgattaa
    10981 ccttggtctt tacgacgatg ttaaaaaaga acttgcagct gcaggtaaag acttgatcga
    11041 agttgaagaa gttgaattgg aaccatctct tggtaatggt ggtttgggac gtttggctgc
    11101 ctgctttatc gactcaattg ctactcttgg tttgaatggt gacggtgttg gtcttaacta
    11161 ccactttggt cttttccaac aagttcttaa aaacaaccaa caagaaacaa ttccaaatgc
    11221 atggttgaca gagcaaaact ggttggttcg ctcaagccgt agctaccaag taccatttgc
    11281 agactttact ttgacatcaa ctctttacga tattgatgtt actggttatg aaacagcgac
    11341 taaaaaccgc ttgcgtttgt ttgacttgga ttcagttgat tcttctatta ttaaagatgg
    11401 tatcaacttt gacaagacag atatcgctcg caacttaact ctcttccttt acccagatga
    11461 tagtgaccgt caaggtgaat tgctccgtat cttccaacaa tacttcatgg tttcaaacgg
    11521 tgcgcaattg atcatcgacg aagcaatcga aaaaggaagc aacttgcatg accttgctga
    11581 ctacgcagtt gtccaaatca acgatactca cccatcaatg gtgattcctg aattgattcg
    11641 tcttttgact gcacgtggta tcgatcttga cgaagcaatc tcaattgttc gtagcatgac
    11701 tgcctacact aaccacacaa tccttgctga agcgcttgaa aaatggcctc ttgaattctt
    11761 gcaagaagtg gttcctcact tggtaccaat catcgaagaa ttggaccgtc gtgtgaaggc
    11821 agagtacaaa gatccagctg ttcaaatcat cgatgagagc ggacgtgttc acatggctca
    11881 catggatatc cactacggat acagtgttaa cggggttgca gcactccata ctgaaatctt
    11941 gaaaaattct gagttgaaag ccttctacga cctttaccca gaaaagttca acaacaaaac
    12001 aaacggtatc actttccgtc gttggcttat gcatgctaac ccaagattgt ctcactactt
    12061 ggatgagatt cttggagatg gttggcacca tgaagcagat gagcttgaaa aacttttgtc
    12121 ttatgaagac aaagcagttg tcaaagaaaa attggaaagc atcaaggctc acaacaaacg
    12181 taaattggct cgtcacttga aagaacacca aggtgtggaa atcaatccaa attctatctt
    12241 tgatatccaa atcaaacgtc ttcacgagta caaacgccaa caaatgaacg ctttgtacgt
    12301 gatccacaaa taccttgaca tcaaagctgg taacatccct gctcgtccaa tcacaatctt
    12361 ctttggtggt aaagcagctc cagcctacac aatcgctcaa gacattatcc atttaatcct
    12421 ttgcatgtca gaagttattg ctaacgatcc agcagtagct ccacacttgc aagtagttat
    12481 ggttgaaaac tacaacgtta ctgcagcaag tttccttatc ccagcatgtg atatctcaga
    12541 acaaatctca cttgcttcta aagaagcttc aggtactggt aacatgaaat tcatgttgaa
    12601 cggagctttg acacttggta ctatggacgg tgctaacgtg gaaatcgctg agttggttgg
    12661 agaagaaaac atctacatct tcggtgaaga ttcagaaact gttatcgacc tttacgcaaa
    12721 agcagcttac aaatcaagcg aattctacgc tcgtgaagct atcaaaccat tggttgactt
    12781 catcgttagt gatgcagttc ttgcagctgg aaacaaagag cgcttggaac gtttttacaa
    12841 tgaattgatc aacaaagact ggttcatgac tcttcttgat ttggaagact acatcaaagt
    12901 caaagagcaa atgcttgctg actacgaaga ccgtgacgca tggttggata aagtcatcgt
    12961 taacatttct aaagcaggat tcttctcatc tgaccgtaca atcgctcagt ataacgaaga
    13021 catctggcac ttgaactaat actcttcgaa aatctcttca aaccacgtca gctttatctg
    13081 caacctcaaa gcagtgcttt gagcaacctg cggctagctt cctagtttgc tctttgattt
    13141 tcattgagta taagatacaa atttatacta atacattttg taaaaaagcg agtttcgatt
    13201 gaaattcgct tttttaatga tgtagatttg ggtcaatctt gtctaaaaat agggaaatcc
    13261 tagatacagt gaaggcttta aatgctggtt tttactgtcc tcagccttat attttttcgt
    13321 agttggttac ctcatatcta ttatattcgc ttacataaag tattataata taattgtagg
    13381 aaagaaggtg tttttatgat atacacactt aaattggtgt tgtttattac ctttcttgta
    13441 ataagcttgt tacctgataa gatttttgga aaaaataaaa aaatttggaa aatagttttt
    13501 gcaatattga cggcagtggc agcattgtca tttatgtact aagttatttt aagaatgtag
    13561 ggaaataaac cctacattct ttttagtttt ttctgttttc taaattctat ttatccaagc
    13621 gattcaacat ttcttgcttc ttcgcttcaa gttctgcacg cttttcttcg atttcggcat
    13681 gttttttctc gagttcagaa caacttgcac cattgctaaa ttcttttcgc catcaggaga
    13741 tagggtgagt cgacatgtct attactcacc caaagcagtc ctacaaagca ggaattttct
    13801 gttacttttt tggaaatagt aacgtttata cagctttgac acttcgtatc aaagcgccaa
    13861 acacactccg aggggtttac agaaagcaga aaaggaatga tctggtataa gatcattcct
    13921 tttctctctt tttctttaag taattatata caatgtacga cgaagtcgtc attgcaatgc
    13981 tgatccacca cctaaaggga actttaaaca acattgataa gataaagaat ataaacaacg
    14041 aaaatacgtt atacccaatt aattttattg tatatctcat gattaaaagt taatccttcc
    14101 gttgttagga atggcatcat ttttatccca taattgtgct aaataagtcc ccggtgataa
    14161 taaattcata gcgaattcta aagcaacatc atttacaaac caactaccta gatatctaga
    14221 aattgctgaa cgaatagcac tttttgctgc atgttttcct tttactttaa ttagatttgc
    14281 aaggcctgca gtagttcctc ctaatgctaa agctattgca gtatctaata gagcacccat
    14341 ttgattaact gtaatacctt gccaaactgc tctaaatgga gagtatgtag gtgggattgt
    14401 ataatcgcct tgtaattgtc ggttaattac ttctttgatc cattgttgtg agacgtctgg
    14461 atgaaaagat tggatttcgt ttgcaagtgt attgatttgt tcttctgtta gagaagtgac
    14521 aggttgaagt tccatatttg tttcaatttg tgatacttgt tcagaagcgt atacagctga
    14581 aacacttgga atcgctgata caattaacac aattgacgtc aaaaaaaccg aaataaattt
    14641 cattaatttg ttcatgagct tttctccttt ttatttgcat ctgcttacat tttatcatat
    14701 actgttatta tagtcaaaaa aatatgctat tatgttaaaa aaatattttt caaaatataa
    14761 atggacggat ttattttgga ttttatttgt tattttgacc tgcctctata ttggtaacca
    14821 tgatttgttt actctcaatc atcaagaatt ctcttttcgt ggtagcgttt ggggtctggt
    14881 actggcctta tatcacttac tattcattga taagtttgtt atatcgaatc gaaaataaag
    14941 attagagcta tgcttgactg tgtactttta ggatttattt tggaggaaga ttttgtctct
    15001 attatttatt attttaaatt tatttatttt gtataagatc tattctttga ggcgggaaaa
    15061 atcgaaatac ttgatttata cggcctatat catatttggg gtaaatgtag tatatggtat
    15121 tcaatggtta ttaaaagaac tgatttcaac tatttcccct taatgtgtat ggaaactata
    15181 acaaaacgca taagattaag gtttgtgtac ctgttcttat acgtttttgt catattgaag
    15241 attttcggta agttttctac ttttgcgaag tctagtttat actcaatgaa aatcaaagag
    15301 taaactagcc gtaggttgct caaagtacag ctttgaggtt gcagataaaa ctgacgaagt
    15361 cagctcaaaa catggttttg aggttgtaga tgaaactgac gaagtcagta accatacgta
    15421 cggcaaggcg acgttgacgt ggtttgaaga gtattagaat gctttcccaa ccaaaatctc
    15481 tgcttcgatg gtaatctctg tcagtttgct ccagtcaatt ttgctctggt caacgtgaaa
    15541 gaggagagga gtcatactga gtagggcttg gagttgttct gctgtgatag tcttagtcag
    15601 agaggcagtt tgactagata ggatggtaaa gtgttcctgg aaatgctcct tgatatcttg
    15661 gttagaatac tccttgtttg tcagctggtc ctgtactctt tgacggattt ctttgaggtg
    15721 attttcagtt gggataacct ttatcaagat accgtctttg gataaaacgc gacgaaattc
    15781 tccatagttg gcaggtgaga agatatcaag cagaatatcc atgttagcgt cttttatagg
    15841 aagtcgtgcc aagtcgccaa cgaaccaatt gactgcccag ttgggttcac ttttagcagc
    15901 gatttggact gaatctttgg agatgtcaaa ggcatagaaa gttttttcag agtgactttc
    15961 ttgtagtttg cgagaataga atccttcacc acaaccgata tccaaaattg ttgtggtagt
    16021 ttttgagctt gcaagcaagt cagatacagc atctaagata gcttggtaaa agccggcttc
    16081 taggatttgt tgacggtttt gaaaattttc cttgtcgtag ttagcagatt gcttgatttg
    16141 agggactaga ttgacatagc caaatttcgc caagtcaaaa gaatgacggt tgcagcactt
    16201 gaaattagtc tctaacagag tcagattttc ttgacagata ggacaggcaa aggcagtcgc
    16261 agaagcaaaa cgctgaagtt tgggcttgag atttgtattc atagtttaag tgtatcaaaa
    16321 gaggcaaatg aaagcaactt taggaataag tagatgggag attcagtaga aataaaacta
    16381 attctccaat ttatagaatg aaattgcttt tatatctaaa ttgctatata ataatgataa
    16441 ggaggaaata agtatgttaa aagaagtatt aaccgttgca aaagttgcga aaaaatcttc
    16501 attatttttg ggtggtgtcg catttggtac ccttggtttg aaaatcttag caagtaagga
    16561 agctaaaaaa ggttattcta aagctttggc taaggcttac aagttgaaag acgagctaga
    16621 tgcatctgtt tctgttgtga agcaacatgg agacgatgtc ttgcaagatg ccaaatattt
    16681 gtacgagcaa gagaaaaaag aagagcaatt agatagcctt ataggtgaat aatatgtctt
    16741 ttaaagtgct acatagagga taccaacata tccgactatc atcttctttt tcacttacct
    16801 tggatattca agactatctt cgttccttgg cgagagatga aaaggggatt gagtctatcc
    16861 agttttacat ggatcaacag cactttactc tacgcataaa agaaggcttt tctgtattag
    16921 ataatgcaga agccttttta aaaagaattg ataaagggaa agtttctgag ttgatgactc
    16981 ttcccattcg tagagaagag agtgcttatt ctattgtttc aggtgcagcg gttaagcgtg
    17041 tactttttcg tagttttgtg ccgtatccta ttcgctatat atggacttgt tatcaggctt
    17101 tgggttatat tagagaagcc tatcaaacac tagcgcgtaa ggaactaacg atggaagtct
    17161 tggactgttc ggctatttta ttgtctttgt ttatgaacca atccaagaca gctagcaata
    17221 tcatgtttat gcttgatttg gggaatcatt tagatcagtg gtccttgaaa aaaactgcaa
    17281 cagatttaga acagagtctt cttgcaaaag agagcgatgt attcctagta cagggcgata
    17341 cggttgttag tatcaagagt tccgatgttc aaataggaga tgtcttgatc ttatctcaag
    17401 gaaatgaaat tctgtttgat ggacaagtag tttcaggttt aggtatggtc aacgaaagtt
    17461 ccttgacagg agagagtttt ccagttgaaa aaagagagtc tgatttggtt tgtgcaaata
    17521 cagtattaga aactggagag ttacgcattc gtgtaacaga taatcagatg aacagccgta
    17581 ttttacagct gattgagttg atgaagaaat ctgaagaaaa caagaaaacg aaacaacgct
    17641 atttcatcaa gatggcggat aaagtcgtca aatataattt cttgggggct gggctgactt
    17701 acctattgac aggttctttt tctaaggcta tttctttcct attggtcgat ttctcctgcg
    17761 ctttgaaaat ctctactcct gtagcttatt tgacagttat caaggaaggg ttgaaccgtg
    17821 aaatggtgat taaggatgga gatgttctgg agaaatatct ggaagttgat actttcttgt
    17881 ttgataagac aggaacaatc acaactagtt atcctatagt tgaaaaggtg ttaccttttg
    17941 gagactatag tgaggaagat attctcagaa tcagtgcctg tcttgaggaa cacatttatc
    18001 atcctattgc taatgccatc gtcaagcaag ctgagataga gggaattgaa catgaggaaa
    18061 tgcatgggaa actccaatat atcgcaagca aggggatcaa atctcatata gatggccaac
    18121 cagttcttat tgggaattat gtcttgatgc aggatgagca gattcatatc agttcagaac
    18181 aaaatgcttt aattgaagag tacaagagtc actacaatct cttattcttg gcttatcaaa
    18241 atgaattgat tggaatgttc tgcattcata ctcctttgag aaaagaagca aaaacagcct
    18301 tggataaact taaggcacag gggaaaaaat tgattctggc aacaggagac accttgatta
    18361 ggacagagga attagtcaaa gatttgccct ttgatcaggt ctatacagac ttgaaacctg
    18421 atgggaaatt tgagttagta gagaaactgc agaaagcagg tcacactatt ttgatggttg
    18481 gagatggatt gaatgactca gcggctttaa ctctatcaga tatcggtgtg gtgatgaatg
    18541 agagtgcaga tatttctaag cagatgagtg atatcttatt gttagataat cgtttggatt
    18601 tcttccaaga gttggattcg ttatcatcat ctttgcaaac actcatcaag aaaaatattc
    18661 aggataccgt tgtcgtaaat agtagtttga ttggctttgg cttatttaat tggttcagtc
    18721 cttcaaatct ctctatctta cataatctaa caaccttgcg cattgtcctg cgtagcctgt
    18781 ctattaaaaa tagatagatg agagttatta acagcaaaaa ggagttacct ttctcgaggt
    18841 taactccttt gtttatagat aaatgttgaa tagtttagta agtcaataca aagtattttt
    18901 tcttcccacg acggataaca gtcagttcat tctctaactt atcagcgtca ctcaagacat
    18961 agtcaagctc ttggatgcgg tcgccgttta cgtagatggc tccgttttgg acgtcttcac
    19021 gggcttggcg ttttgagtta actataccag atgagacgag cagttccacg atattgttgt
    19081 tttcgtctgc ctgtacttgg tagttgggca caccacgaag tccttgtttg agctctttga
    19141 cagaaaggtt tttgatgttt cctgcaaaga gttgctcagt gatgttaagt gcttctttgt
    19201 aggcttcttc tccgtgaaca agtgtaacaa cttcacgagc caagactttt tgagccaagc
    19261 gttcgtgtgg cgctgcttca aattgtttac gaatatcttc aatctcatca agtgacaaga
    19321 aagtaaagat tttcaagaag cgaacagcgt cagcgtccat cacgttcatc cagaattggt
    19381 acatttcgta tggagaagtc ttttcgggat tgagccagac ggcatttcct tctgatttac
    19441 caaatttctt accagttgca tctgtgatta gtggaacagt gataacgtga ccagtcttgt
    19501 ccgccttacg acgaagcaat tcggtaccag ctgtcatatt tccccactgg tcagaaccac
    19561 cgatttgaag agtgacatta tggtcttggt taaggacgaa gaagtcatac ccttgcatga
    19621 tttggtaagc gaactcagtg taagaaattc ctgtttcgat ccgtttttta acagattcct
    19681 tactcatcat gtagttgacc gtgaagtatt ttccaatatc acggaggaag tcaatgaagc
    19741 tgatgctgcc aaaccagtcg tagttgttga ccatgacagc cttgttttcg ccattttcaa
    19801 agtcaagaaa acgagaaagt tgtccttgga tagacttgac ccagccatct actgtgtctt
    19861 ttgtttggag actacgttca gcatctttga aggacggatc tccgatgaga cctgtagcac
    19921 cgccaacgag cgcataaggt ttgtgacctg ctagttgcaa gcgacgactt gtcaagattg
    19981 cgacaaggtg gcctaggtga aggctgtcag cagttggatc gtagccagta taataagaaa
    20041 cttgaccttc ttctagggct ttacgcaaag cttcttcatc agtcgtttga aatatcaaac
    20101 cacgctcttt tagctcatca aaaatgtgca tgtgtttttt ctccttttta aaattattgt
    20161 ttctacctat tgtatcacaa acttgggcaa tagcctagca gaatagggaa gaaagtggct
    20221 attttattga aaatttccct tttgtggtat aatagataaa gtgaggaaat ccatgcaaaa
    20281 tcaattaaat gaattaaaac gaaaaatgct ggaatttttc cagcaaaaac aaaaaaataa
    20341 aaaatcagct agacctggca agaaaggttc aagtaccaaa aaatctaaaa ccttagataa
    20401 gtcagtcatt ttcccagcta ttttactgag tataaaagcc ttatttaact tactctttgt
    20461 actcggtttt ctaggaggaa tgttgggagc tgggattgct ttgggatacg gagtggcctt
    20521 atttgacaag gttcgggtgc ctcagacaga agaattggtg aatcaggtca aggacatctc
    20581 ttctatttca gagattacct attcggacgg gacggtgatt gcttccatag agagtgattt
    20641 gttgcgcact tctatctcat ctgagcaaat ttcggaaaat ctgaagaagg ctatcattgc
    20701 gacagaagat gaacacttta aagaacataa gggtgtagta cccaaggcgg tgattcgtgc
    20761 gaccttgggg aaatttgtag gtttgggttc ctctagtggg ggttcaacct tgacccagca
    20821 actaattaaa cagcaggtgg ttggggatgc gccgaccttg gctcgtaagg cggcagagat
    20881 tgtggatgct cttgccttgg aacgcgccat gaataaagat gagattttaa cgacctatct
    20941 caatgtggct ccctttggcc gaaataataa gggacagaat attgcagggg ctcggcaagc
    21001 agctgaggga attttcggtg tagatgccag tcagttgact gttcctcaag cagcattttt
    21061 agcaggactt ccacagagtc ccattactta ctctccttat gaaaatactg gggagttgaa
    21121 gagtgatgaa gacctagaaa ttggcttaag acgggctaag gcagttcttt acagtatgta
    21181 tcgtacaggt gcattaagca aagacgagta ttctcagtac aaggattatg accttaaaca
    21241 ggacttttta ccatcgggca cggttacagg aatttcacga gactatttat actttacaac
    21301 tttggcagaa gctcaagaac gtatgtatga ctatctagct cagagagaca atgtctccgc
    21361 taaggagttg aaaaatgagg caactcagaa gttttatcga gatttggcag ccaaggaaat
    21421 tgaaaatggt ggttataaga ttactactac catagatcag aaaattcatt ctgccatgca
    21481 aagtgcggtt gctgattatg gctatctttt agacgatgga acaggtcgtg tagaagtagg
    21541 gaatgtcttg atggataacc aaacaggtgc tattctaggc tttgtaggtg gtcgtaatta
    21601 tcaagaaaat caaaataatc atgcctttga taccaaacgt tcgccagctt ctactaccaa
    21661 gcccttgctg gcctacggta ttgctattga ccagggcttg atgggaagtg aaacgattct
    21721 atctaactat ccaacaaact ttgctaatgg caatccgatt atgtatgcta atagcaaggg
    21781 aacaggaatg atgaccttgg gagaagctct gaactattca tggaatatcc ctgcttactg
    21841 gacctatcgt atgctccgtg aaaagggtgt tgatgtcaag ggttatatgg aaaagatggg
    21901 ttacgagatt cctgagtacg gtattgagag cttgccaatg ggtggtggta ttgaagtcac
    21961 agttgcccag cataccaatg gctatcagac cttagctaat aatggagttt atcatcagaa
    22021 gcatgtgatt tcaaagattg aagcagcaga tggtagagtg gtgtatgagt atcaggataa
    22081 accggttcaa gtctattcaa aagctactgc gacgattatg cagggattgc tacgagaagt
    22141 tctatcctct cgtgtgacaa caaccttcaa gtctaacctg acttctttaa atcctactct
    22201 ggctaatgca gattggattg ggaagactgg tacaaccaac caagacgaaa atatgtggct
    22261 catgctttcg acacctagat taaccctagg tggctggatt gggcatgatg ataatcattc
    22321 attgtcacgt agagcaggtt attctaataa ctctaattac atggctcatc tggtaaatgc
    22381 gattcagcaa gcttccccaa gcatttgggg gaacgagcgc tttgctttag atcctagtgt
    22441 agtgaaatcg gaagtcttga aatcaacagg tcaaaaacca gagaaggttt ctgttgaagg
    22501 aaaagaagta gaggtcacag gttcgactgt taccagctat tgggctaata agtcaggagc
    22561 gccagcgaca agttatcgct ttgctattgg cggaagtgat gcggattatc agaatgcttg
    22621 gtctagtatt gtggggagtc taccaactcc atccagctcc agcagttcaa gtagtagttc
    22681 tagcgatagc agtaactcaa gtactacacg accttcttct tcaagggcga gacgataatt
    22741 ctctaaatga agtggccaat caatggattg ccactttttt cctttcgtgt tacaataagg
    22801 gtatgaatca gtatcagaaa aagattgtta acggaaaaat ttattcgctc ctatccggct
    22861 taatatgggg aatctgtgga attttaggag agtacttctt tactcattat caggtgtctt
    22921 cgggctggat tacctctatg cgtttgacac tggcagggag tcttgtactc atttggtctg
    22981 caatacaatt aaaatcgcaa gtgctagata tttggcgaga caagaaaaat tacctgccct
    23041 ttttagccta tgctattttg gggatttttt cagttcagta ttttttctat ctctgtgtag
    23101 aatactcaaa tgctacgaca gcaactattt tacagtttat tagccctgtc tttatcctct
    23161 tttacaatcg cttggtttat caaaaacgag cgtcaaaaag cgctgttttc tatgttttgg
    23221 ttgccatgct gggtgtttgc ttgatggcga caaagggaga cctctctcag ttatccatga
    23281 cgccgctagc tcttataaca ggtttgctga gtgccatggg tgttatgttt aatgttatct
    23341 tgccccaacc ttttgctaag cgttatggtt ttgttcctac ggttgggtgg gggatgattt
    23401 tggcaggttt gtttagcaat gtcctctcgc cggtttatca gctttccttt actcttgata
    23461 tttggagtat cttgatttgc ctcattatcg ctttctttgg aacggctttt gcttttttca
    23521 tttccatgaa ggctgtgtcc ttggtttctc ctttggtggt tgccgttatc agtgccagtg
    23581 aacctctctc ttctgctctc ttgagtgttt tgttcttagg attagtagtg gattggtccc
    23641 tccttctagc tatagccttg attattttac ccatgatatt tttgtctata gaagaagcga
    23701 aagaaagtag ataaaaagtc ttttcttaat tctaaaagtg tgctatactg gaatagtcaa
    23761 taaaacacgg ggagatagtt gtgaagagtg tttttaggtt gtatcggtag gggcttgctt
    23821 ttaccgacag cacgttttat ctcacatccc taaaaaatca tacctaaaaa cagacaaaaa
    23881 ggtttcaaat ttgaggcctt ttttggtaga ataggtatca ttataacgaa ccaggaggca
    23941 cctatgactg ctacaaaaat gaacgctcaa gaaattatcc aatttatcgc caatgctgaa
    24001 aagaaaacca gtgtcaaagt aacctttgag gggcaactcg caactgctgt gcctagctct
    24061 gttgtcaaac taggaaatgt cctattcgga gactggaagg atgtggctcc gcttcttgaa
    24121 ggtttggtag aaaatcaaga ttatgttgtc gagcaagatg ctcgtaattc tgcagttcct
    24181 ttgctagata agcgtgctat caacgctcgt atcgagccag gcgcgattat ccgtgaccag
    24241 gtggaaattg gtgacaatgc tgttatcatg atgggatctg ttatcaatat cggtgctgaa
    24301 atcggtgctg gaaccatgat tgacatgggt gccatccttg gtggccgtgc catcgttgga
    24361 aaaaatagcc acgttggtgc aggtgcagtt ttggcaggtg tgattgagcc agctagtgct
    24421 gaaccagtcc gtgtcggaga caatgttctt atcggtgcta atgcagtggt tatcgaagga
    24481 gtccaaatcg gtagtggttc agttgtcgca gcaggagcta ttgttaccca agatgtccca
    24541 gaaaacgtgg tagtagcagg tgttccagct cgtattatca aagaaattga tgcccaaact
    24601 caacaaaaaa cagcgctaga ggatgcgctt cgtaccttgt aattgtaaaa gtaaaaaaga
    24661 ggcggaaccc tttttccagc ctctttctgc tatatcggag gacagataga tgttagattt
    24721 gattcagact agacgagatt tacaccagat tccagagatt ggcttggagg agttcaagac
    24781 tcaggcttat ttgctggatg tgattgagaa attgactacg ggcaaggatt ttgttcaaat
    24841 tcgtacttgg cggacaggga ttttggtcta cctgcaggga agtcagccgg agcgaaccat
    24901 tggttggcgg acagatattg atggcctgcc tatcgtcgaa caaacaggtc taccttttgc
    24961 ttctcaacac caaggtcgca tgcatgcctg tggccatgat tttcatatga ccattgcctt
    25021 aggctgtctt gagcgcgccc ttgaggagca acccaagaat aatctgctct ttctatttca
    25081 gcctgctgaa gaaaatgaag ctggtggtat gctcatgtat gaggacggtg cttttggaga
    25141 ttggttgcca gatcaattct atggtctcca tgttcgtcca gatttgaaag tcggccagat
    25201 tgcgactaat actcatacac tctttgcagg aacttgcgag gtgaagatcc gtttcaaagg
    25261 caaaggtggc cacgcagctt ttcctcatga agccaatgac gccttggtgg cggctagtta
    25321 ctttgtgacc caagtgcagt cagttgttag ccgcaatgtc aacccaatcg agggagcagt
    25381 ggtgaccttc ggcgtttttc aagctggaac caccaacaat gtcatcacag acacagcttt
    25441 tttacatgga actattcgtg ccttgacaca ggacatgagt ctcttggtgc aaaagagggt
    25501 aaaaacagtt gcagaagggg ttgcagctgc ctttgatatg gaagtcgaag tggaactcaa
    25561 acaaggtgga tacctacctg ttgagaacaa tccagccttg gcgcgtgaac tgatggactt
    25621 ctttgacgaa aaagacggaa tcgagttgat tgatatcgaa cctgctatga caggcgagga
    25681 ctttggttat ctcctttcaa aggttgatgg cgtgatgttt tggctaggta tcgatagtcc
    25741 ctacgctctt catcaccctc aaatgagtcc taaggaagaa gtcttagcta ttggggtggc
    25801 tgcggtgtct agtttcctga aaaagaaggc agcagaatag agggcttgtc tatgaaatcg
    25861 gaattacgca agcaagtctt gcatgaaatg aaggctatat ctcaagagca aaaacaggct
    25921 atagaccaag ctttaaccga gcggctttta caacacccct tttatcaaga agccaaggtc
    25981 atcgcaacct acctctcttt ttctcatgag tttcaaacgc aggaactgat tgagcaggcg
    26041 ctgaaggacg gcaagaaggt tttaataccc aaaacttatc ccaaggggcg catggacttt
    26101 gtggtctatg atccgcaaca gttggtaaaa actttctttg ccttactgga gctacaggga
    26161 gatttggaag tggtggatgc atctcagatt gatttgattc atgttcctgg tctggctttt
    26221 acgacgaaag gatatcggat aggatacggt ggaggctatt atgaccgcta tctggaacat
    26281 ttttctggtc gtactttgag tacgatatat ccttgtcaaa ttcaggactt tatacctgaa
    26341 aaccatgata ttcctgttca ggaggtatta attgatgaag gaaatctttg atagacgtta
    26401 ccctgtgacg agtttcttcc tcttagtgac ggccttggta tttttactaa tgttggtcac
    26461 tgcaggcgga aactttgaca gggcagatac attatttcga tttggagcca tgtatgggcc
    26521 agctattcgc ctctttcccg agcaggtttg gcgtctcttg tctgccattt ttgttcatat
    26581 tgggtgggaa catttcattg ttaatatgct ttcactttat tatcttggaa ggcaggtaga
    26641 ggagattttc ggttctaagc agtttttctt tctctatctt ttatcaggaa tgatgggcaa
    26701 tctctttgtt tttgtattta gtcctaaatc cttagcagca ggcgcctcta cctctcttta
    26761 tgggctattt gccgcgatta ttgttcttcg ctatgcaact cgcaatcctt atatccaaca
    26821 gctagggcaa tcctatctga cactttttgt ggttaacatt attggaagtg ttctgattcc
    26881 aggaatcagc ctagcaggcc atatcggtgg tgcagttggt ggcgcatttc tagcagttat
    26941 ctttccagtt agaggagaaa aacggatgta taacaccagc cagagattag gagcggtagt
    27001 cttgttcgta ggactcgcca ttttgctttt ctacaaggga atgggattgt gacgactaat
    27061 actcaatgaa aatcaaagag caaactagga agctagccgc aggttgctca aagcactgct
    27121 ttgaggttgt agatagaact gacgaagtca gctcaaaaca tggttttgag gttgtagatg
    27181 aaactgacga agtcagtaac catacctacg gtaaggcgat gctgacgtgg tttgaatttg
    27241 attttcattg agtataatat gtaaacttga ataagaaaaa agctacttaa aaaatgagta
    27301 gcttttaatg tgttttggaa ccattcgaaa caacacagct ctaaaatagt tattagcgtt
    27361 gactaggttc tgcaatgccg ccaccaaagt tcccaaggta atttccatcg tcatcataca
    27421 catctccatt attatgatct ttgtagtagt atctttgata gccgtcagca ccagtgcctt
    27481 tatatctgta gacattattt gctccgctgt ttgaattgct agatgaatat tgttctgatg
    27541 atccaccatt tgttgaacta tctcctgaac cagaataatc ttgaccgcca taattatttg
    27601 aatatccatt agtttgttca gatgaactat aatctacatt tgaattggaa gatccattat
    27661 aagactcatt agaagcacta ccagaagaat tactttgact agaagattcc tttgcttttt
    27721 cagcagcttt ttcttcttct ttcttcaaaa gttcgatttg tttttgatat ttatcaacaa
    27781 gatcatttag agatttaaga gtttcttcca aattctcttg tttaaaagtt tcatcaactt
    27841 ttttgataaa atcaatttgt tttgtaattt cttttacatt tgtttcaaga gttgctttat
    27901 ctttaaattt gtcatctgaa tctttaacat cataagccaa acctttttgc aaatgaaaat
    27961 ctacaattgc tttagatgat tctttgactt tgttattaag atagtcttta cctgcatcgg
    28021 ttttaagtga agtttcagat agttctttta atttagaaat agattcatct gaagatgcat
    28081 caaatgattc aaatagttta tcaacttgtt ctttgtctga tttgctatct ttttctaatt
    28141 gtacaatttt tgcttgttgt tctgcttgtt gttggttata tgaataccat ccaaacccta
    28201 ataccaatac aacaccaact gcaactgatg aaatgattac ttttttattg ttttcgataa
    28261 attctacaaa tttgttctcc ataatctttt tctttgatag tgtccgcaat tactttaaaa
    28321 ttaaaattac acctatcttt ctcccttatt atatttttat taatagcttc cacaaaatta
    28381 aacaacttat gttcggctcg gttgatttaa tttaaccatg actactccaa cagttaagtc
    28441 aaatttaaaa ttatttatta ttttggaacc attagaaaca acatagcaaa gttaaaataa
    28501 ggctttgtcc gtacacaact tgaaaaagtg cgcaccgatt cggtgctttt ttgttttact
    28561 atactaattt attctactct tattttaatg aaaaaacaaa tacaagtata gcgttttcat
    28621 tagtttttat taaataggta gattcaagta gagaatttac ttaatttatg tgtggctaat
    28681 ctttatataa atgattttgt tattccttct cagtcaattc ttttccaagt tggatgaggt
    28741 aattcttcaa atcatctttg acttgtgggt gtttgagggc gtagtcgatg gatgttttca
    28801 tgaagccaaa cttgtctccg acatcgtaac gagccccttt gaactcacga gcaaatacac
    28861 gttgtgtttt attgagggtg tcgattgcat ctgtcagctg aatttcattt cctgcacctg
    28921 gagcttgctt ttcgagaatc tcaaaaattt caggcgtgag gaggtagcgt ccgataatag
    28981 caaggtcgct aggagcgtcc tctggagctg gtttttcaac aaaggtttca acactgtaaa
    29041 gaccatcttt tccttcgcct tgcggagcaa taaccccgta agcagatact tcgtcatgag
    29101 ggactggcat gacagcgata gtagacgcgt gggtacgctc gtagtcatcc atgagttgtt
    29161 tggtaagtgg aacagccttt tcgtctgtga tatccatcaa gtcatcacca agcataacga
    29221 caaaaggttc atttccgacg aaagccttgg cttgcaaaac agcatctccg agaccgcgtg
    29281 gatgagtttg gcggataaaa tgcagacgca tgtcagttgt tttatcaact agcttcaaaa
    29341 gatctgtttt ccctttttct ttgaggttat attccaattc gaagtttgaa tcaaagtggt
    29401 cctcaataga acgttttgat ttaccagtga caactagaat atcttcaata cctgatttga
    29461 gagcttcttc cacgataaac tggatagttg gtttgtctac gattggcaac atttctttgg
    29521 caagggcctt ggttgctggt aaaaatcgag ttcctagtcc agcagcaggg atgactgcct
    29581 ttctaacttt tgatgtcata aaaatccttt ctatagaggg ttaagaccac tcattttctg
    29641 ctttaaattc attgttcatg atgtcataaa tggcatcttt gatattggtt ccgtgataaa
    29701 taacttggta aatagcctgt gtaatgggca tatagactcc aagttcttgg gctagttcat
    29761 aggctgctcg agtcgttgaa attccttcga ttaccatgcc catattagct tctatatcag
    29821 ctagggattc tcctcgtccg agagcatctc cagctctcca gttacgagag tggatggaag
    29881 ttcccgttac gatcaaatct cccacaccag ataagccgct ataggtcaat ggactggccc
    29941 cgagtgctac ccctaggcgg gtgatttctg ctaaacctcg agcgatgatg gctgccttag
    30001 cattatcacc aaatccaaga ccatgtaaag ctccagcacc gacagcaata atatttttaa
    30061 gagcaccagc agtttcaacc ccgataacat ccgtattggt ataaagtcgg aagtagtgat
    30121 tactaaatag cttctgaacg tattgagctg tttgtaaatc tttagaagca gcagttatta
    30181 aagttaggtc acgcacaatg gtctcttctg catgactagg ccctgaaaca acgacgatat
    30241 cactacggag atgttcagga atttcttctt caagaatggt tgataatcgt ttatggctat
    30301 caggttctaa tccctttgat gcgtgcatga tgataacctt atggtccaag gtttgtgcaa
    30361 cttgctgggc aacaagtcgt gtcacttttg ttgggacaac aaacaaaatc gcatccacat
    30421 ctttcaatgt ttctgctaag tcggtgtagg caatgatatt ttcgtctaga acgacatctt
    30481 taaagtagtg cttattagta tggtgtgtat taatttcatt gatttgctcg ggaagatttc
    30541 cccaaatacg tacctcgtgt ccattgtcat ttaagacttg tgaaagggcg gttccccaag
    30601 aaccaggccc caagacggcg acggtttgtt tttccatgat ttcctccttg atagagttct
    30661 ttctcttatt ctatcatatt ctaggggatt ttgcacttgc attactgggg tatggtggaa
    30721 aaatacacaa aaaccgagac gaagggataa actcttagtc tttagttaaa gtgagaagaa
    30781 atctgataga tagtttgatt cagtatatgc ttataataga ggtaaacaac tcaggaagtt
    30841 cttgtaggtt gcgagagttt ggcgaaaaaa ttaaaagatt acgtttggct aaaaaaatca
    30901 gtcgttcaga attttgtggt gatgagtctg aattaagtat ccgtcaatta attagaattg
    30961 aaaatggaga atccagacca atactaacaa agttaaaata tattgctgaa cgtttggggg
    31021 ttgaagatta caagttgatg ccaagttata tagagttgga taaggaatac ctagaattga
    31081 agtatttctt gatgaggact cctacatacg aagatgaaac tatcgcccaa aagaaagaga
    31141 gtgtttttga taagattttt gaagagtatt atgataggct acctgaggaa gaaagattta
    31201 tcatcccaaa ttattcatat ctggcactaa cgaactacac agttcaaaaa ttaccagaaa
    31261 agctagttga aatactgtcc ttctggtgat tttgcttaat ttctgatgtt cgagacataa
    31321 ttgaggagat ttgtcttgat tttttcctaa aaaagggcag actcctccct tggtttgatg
    31381 ctcgattttt aaaataaggt gacttattct gttaggcatg ttttcccctg ccctctagct
    31441 ctatatggaa cagggagtat cagatttatc tggcagattg tatcaaataa ggcttgaaac
    31501 tgttttgaat aggcgtatag acttgagaat ttgagaatat gtcgtctagc agtagagaca
    31561 tattttccgg caatatgaag gaagagacgt cgaaaacgct tgatagtcaa ggactttact
    31621 tcatcaccag ctagctgctt taaaaagagg tagagattat aagccagaca gcccatcatc
    31681 atacgtactt cattcttaat catggtcgaa ctatctgtct tatccccaaa gaatcctgct
    31741 ttcctttctt tgataaagtt ttcagcattc cctcgttcac gatagaattg aaacaactcc
    31801 tcactatcta cactgcttaa attggtcaaa tgaacttttt tacaaccata aaaaagagta
    31861 cttaatcgta ctcttctctt ttaaggatta gttgaattaa ttcaaatcca ctagttctcc
    31921 tgtttctagg tagactaggc gttcacaaat gttagcaatg taatcagcga agcgttccag
    31981 atgccctatg atataaaggt attgagttcc attgggaatt gaggtttctt ggtctttcat
    32041 aagtccaatg atttcctttg ataaggcata ataatattgg tcaatctgtt catctttttg
    32101 agcaatacta atagcttttg aggcttggtg caaaggaaag gcaaccaata aatcggctag
    32161 catgctgagg gataatttac ccatttggtg taactgttct tcgtcagggg ctagttgatt
    32221 ttcttttagt tgcaaaacag ctttggcaat gcctgccata tggtctccca tacgttcaag
    32281 gtctgaacaa gaagacatga tgctaatcac aaatcgaagg tcagacactt gtggctgctg
    32341 caaggccaac aaacgggcac aggtcaattc gatagcgctt tgaccttggt tgatagcatg
    32401 atccttattg ataattagct ctgccatctc cttgtctttg gaggctaagg ccagtaaggc
    32461 ttttgaagct gtttcaagga caagttgccc tagtcctaaa aaggattgtt ctaattcatg
    32521 caattctaag tcaaattgat ttctcatagg tttttccttc cttatccgaa ccgtcctgaa
    32581 atatagtctt ctgtgcgctg atcttttgga ttggtaaaca cgtcaacggt atctccaaat
    32641 tcgcaaattt ctcctgttaa gaaaaaagca gttttatctg aaatacgtga agcttgttgc
    32701 atgttatggg taacaatgat aatcgtataa tcctttttta gttgctgaat gaggtcttca
    32761 atttttaaag tggagatagg gtctaaggct gaagtcggct catccattaa cagaatatca
    32821 ggttctactg ctaaagctcg cgcaatgcaa aggcgttgct gctgaccgcc agataaggac
    32881 atggcactct ttttaagatc atctttgact tcttcccaaa tggctgcccc ttttaaagat
    32941 ttctccacta aggcatctaa ttgttttttg tctcgaatac catgtgtcct tgggccataa
    33001 gccacgttat catagataga catggcaaag ggattaggct gttgaaaaac catccctaca
    33061 cgcttacgta gctgattaag gttgaatttg ctactataaa tatcttgctc atctaagagg
    33121 acttggcctt caatatggca agaaggaacc aaatcgttca tccggttaag ggtttttaga
    33181 aaagttgatt tgccacaacc agatgggcct atcaaggcag taatctgtct ttctggtaat
    33241 tgaatcgaaa tattttttaa ggcttgaaaa tccccgtaaa ataagtctag gtgtctgact
    33301 gaaaatgttc ccatactagg aagctccttt cacaagtttt cgagataata agcttgatag
    33361 agtatttatc attaaaacag taataatcaa aatcacgccg gtagcatagg cttcattgac
    33421 atgtagcccc tcacttgaca gcatatacat atgtagggct agagaacggc ctgaagacat
    33481 gagactactt ggcgtattgg tagaggtacc taatgtatac atgagggcag ctgtttcacc
    33541 aacgatacgg ccaatagcta gtatcactcc agctaaaata cctggcatgg caactggtag
    33601 aacaattcta aaaacagtcc gtaacttacc tgccccaagt ccataacttg cttgacgcat
    33661 gctatcacta acagataaaa gggcttcttc tgttgagcga ataatgactg gcaacaccat
    33721 gataactgag gttaagattc ctgataacag agagtattga aaacctaaga agactacaaa
    33781 gaagagcatg ccaaacagac caaaaacaat ggaaggaatc ccagataagg tatctgaggc
    33841 caatcgcatg attttaacac aaagggaatc tttttttgta tattccacaa gataaaaacc
    33901 agcaaaaatc cctatgggca aggctaaaag aagagcacca aagaccagaa taacggtgga
    33961 aataatcgct ggcataaggg aaatgttctc agaagtataa gtccaagaaa agagggatag
    34021 acttagatga ggtaagcctt tgatgaggat aaaaccaatg attaaaaaga gagagccaaa
    34081 ggttaaagct gaaaaacaat aaacgagaag ttttagcagg tatttactca taagatgatt
    34141 ttcctttcaa gtaggcaaag taggcattaa tcaagagaat aaggaaaaag agaactgctg
    34201 aggttgcaat aagggcttcc ctatgctgac ctgatgcgta agccatttcc agaacaatat
    34261 tggttgttaa ggttctggtt cctgaaaaga gtccacttgg aataatcggc tggttgcctg
    34321 ccaccaaaat aactgccatg gtttcaccta ctgcgcgacc gattcctaaa ataactgctg
    34381 ataaaatacc agatctcgca gctggcaaga tgacactaaa aatactccgt tcatgactag
    34441 ctcctagagc caagctacca gaataatacg ttttgggaac tgttcggata gcagattctg
    34501 acaaactgat aatggttggc aaaatcatta ttcctaatag taacgaagcg gttaggacac
    34561 tcatgccatt tcctaaaaag cttctaatcc aaggcaccaa taattgtagg ccgaaaaaac
    34621 cataaacaat agatggaatg gctgccatca agttgatagc tgattttaag aagccataga
    34681 cgggctttgg acaataataa accataaaca ccgatgtcaa gatgcctgtt ggcaccccaa
    34741 tcacaatcgc tcctaaggta attaataagg aaccaacgat cattggtaaa ataccatagc
    34801 ttgccggaat gttcgttggc gaccaatcac tgcctaataa aaaacgggca aagccgtagt
    34861 tagctatgaa aggtaagcca ttactaaaaa taaagaaaca gattagcaaa atagctacaa
    34921 cagctactgt tgcactcatg aaaaaaattg ccctaaaaac tgcttctttg aaggcttgtt
    34981 ttgtcacatc ttgtcctttc tagtgaagaa agtaagggag atacgacacc tccctacttg
    35041 ccttctttat cttattgtac gatgaaacgt ctgcatctct ttagagattt atggagcaaa
    35101 cattttattt aatcttgtcc caggtggtta atttgccact aaaaacgtct gcaagttcag
    35161 ccatactgac ttggcttgcc ttattgtcat tattgaccac aacagcaata ccgtctaaag
    35221 caatagcatc atgggtgaga ctcttacctt cttcaggagt taattcccta gaaaccatac
    35281 caatatcagc ggttttctcc ttaacagcgg taatacctgc tgaagaccca ttagaggtaa
    35341 tatcaatcgt aacttctgga ttttcttttt tataagcttc tgctaatttt tccattaaag
    35401 aagatactga agtggaacct acaacagaca acttgcctga taagtgttgg cttgtatatt
    35461 ccgtggtttc ggttttagct tcaataaatt tattatctgt gaccacttgt tgaccttgtt
    35521 tggagtggat aaagctgata aaatcttgac ctagcttgga aagattagaa gaccaaacaa
    35581 tgttgaaggg acgttgaaga gggtattcac catctaaaac tgtgtctcga ctagccttga
    35641 caccatcaat ctctaaagcc ttgacagatt tcgttaaaga tcccaaggag atgtagccga
    35701 tagcattagc attcccttga actgctgaga gaacaccttc tgtactattt tgaatcacag
    35761 ctgttttggc agtgttgtca atttttttat caccgtcttt tttgagaatc cctgtgattt
    35821 ctgtgaaggc accccgtgtc ccagagccat tttctcgtga aatcacctca atcgttcctg
    35881 aagctgactg tttggaagca gctgactgat tgccacaggc aacaagccca aatcctgata
    35941 agccaatggc tgcaagagta agcatttttt tgaatttcat aataatcacc tttatctcta
    36001 tgtatttttc ttgtgtaggc ttactacatt tatagtctaa caagtctttg taaaggttta
    36061 tccctgattc atgtaaagat tgtgtaaaga atcaaaaaaa gccacttttg aaaaatggct
    36121 gctcctaaaa atagctttaa aaattattag tcctgtgcga aagattggtt aggaagaaaa
    36181 atcgtgaagc aactgcctct gccaagctga ctcgtcaccg tgacttggcc acctaataat
    36241 tgactgagtt ctttgacaat ggcaaggcca agaccagtgc caccagtttg tctgcttcga
    36301 cctttattaa ctcggtaaaa acgttcaaaa atacgatcct gctctaattg actaatacca
    36361 atccctgtat ctgatacaga aatcttaatg ccttcgttca ccttttgggt cttgacctca
    36421 atttttcccc cttgttcagt gtaacggatg gcattggata aaagattgag taagatttgg
    36481 gaaagtaatt gactatctga tacgagggtg acatcatctg gcacctgcac ctttagctgt
    36541 aaatccttct tcttgagctg aggttgcaag ctttgagtca aatcctgtac aaattctgcc
    36601 aaagaaaggg tcgtccattg tataggcatt tgttgagcct tagataaggt aagaagatgc
    36661 tcaacaatat gctcaagacg caaactttct ttgtaaataa tgtctagaaa gtcatccttg
    36721 agcgcttctt cttcagctga catcccctta atggtttcag caaagccctt aatcgaagta
    36781 actggtgtcc tcaattcatg ggaggcattt gagacaaagg ctaaatttaa cttttcataa
    36841 gttctaatcg ttgttaaatc atatagcaag acgagcacag cttccacaga ttgggtgggg
    36901 ctaaaaacgg gaactgctgt cacttctaaa atcaagtcac cctcatgaaa cccacttact
    36961 tcttgtttta accttgtttt ttgatcaaag gcttggtgaa ctaaattccg aatatccatc
    37021 cgtttgaggt catcaagtga acttatgtcg ccgtccacat cgggaaaata atgaggcaga
    37081 gagcgactgg ataataacat ctgaccttga gcggaaacta aaaacgtccc catggttagg
    37141 tgcgacagaa gaacctccat tgtttcggct agatccttgt attgctgatc ctgttgggag
    37201 actttggttt ttaggccaga cacatactga gccaaagact ttaagtcttc ttgccctttt
    37261 tctaaaaagt attcactact ggtcaagaga ggttggtgca aggtctcaaa agcaacttcc
    37321 catttccaaa ggcaaaagag ccagtagcca cctagtccca aagaaagggc tagaagaaag
    37381 agaccgatgc ctttactgat ccaagttaat gccatccctg caatcagaat gaggctaaca
    37441 cttagattga ctagccaaaa ttgaaggtag cgtttcatct ataactcctt gaacttataa
    37501 ccataacccc gaatggttcg aataaattga ggggctttag gattgtcttc aattttttcc
    37561 ctcaacttac caatatgaac gtccaccaaa cgtgtttcct gcccaaagtc atacccccag
    37621 atacgttcca aaagacgctc tctagtcagt gtcatgttgg gatgtttcat aagatagagc
    37681 aagagttcaa attcttttgg ggtcaaactc agtaacttat tcgccttgta gacttcatga
    37741 cgctcagggt atactttcaa ggtcccaaat agccaagaat cgtcagcgat attatctgaa
    37801 tcatctcctt cttgttctcc tttagttcgc ctgaggacag ccttgacacg cgccagcaat
    37861 tctctagggc taaaaggctt ggtcaggtag tcatcagccc ctaattccaa ggccaaaacc
    37921 ttatcaaatt catcactttt cgcagaaacc atcataattg gagttttgac gcctttggct
    37981 ctcagccgct tacaaacttc catgccatct aattgtggta acatgatatc aagcaagata
    38041 aaatcaaagg gttctgtttc tgccaaagct aaggccttcc gtccatttgt caccaattga
    38101 gtagaaaagc cttccttact taaatggtag tcaagcaatt tcagaatgtg ttcttcatca
    38161 tccactaata agacttgttt tgtcatctat tatctcctat tggtaacatt ataacacaat
    38221 tatcagaaat cctaacattg ctaaatcaga ttaaatttgc ctatcaagac tagtatctgg
    38281 tcaaacgctc aatcatctcc ttgtgctctg gataggtcgc cagtagatct accctttcaa
    38341 ataattcaaa atcctcaaat tcaaaaccag gagcaacaag acaagaaacc agagcatcat
    38401 ccttatcaac tgttgatccc caaatagtgc ccttaggaac acagtagtga agttgttgcc
    38461 ctttggatat gtccaggcct aaagtgactg cttcgtagtg accatctgct gtaatcatgt
    38521 gaacagtaag tggggatcct gcatgaaaat accagatttc atctgctgtc aatcggtgaa
    38581 aatgtgaagg attcgtttct tctaataaga aataaatact ggtataaagc gcccttccct
    38641 taccagcaag gtttatagtg tctgaagctt tttttgtttg tctaaaatag ccaccttcaa
    38701 tatggggagc taactctaga gttcttatca agtcttcttt atccgtcgga gccaatgggt
    38761 tgaagtaact cttgttcaaa gtggttttac gatttcaaga actcctctca gttctgagga
    38821 cacggtaatg attgatgcga cggaagtaca aatcaatcgc cctaaaaaaa gaattagcga
    38881 atgattctgg taaaaaaaat gccacgctat gaaggctcaa gcgattgtca caagtcaagg
    38941 gagaattgtt tctttggata tcgctgtgaa ctattgtcat gatatgaagt tgttcaaaat
    39001 gagtcgcaga aatatcggac aagctggtaa aatcttggct gacagtggtt atcaagggct
    39061 catgaagata tatcctcaag cacaaactcc acgtaaatcc agcaaactca agccactaac
    39121 agttgaagat aaagcctata accatgcgct atccaaggag agaagcaagg ttgagaacat
    39181 ctttgccaaa gtaaaaacgt ttaaaatgat ttcaacaacc tatcgaaatc atcgtaaaca
    39241 cttcggatta cgaatgaatt tgattgctgg cattatcaat catgaactag gattctagtt
    39301 ttgcaggaag tctattattt ggttaggtga attagtgaag cgtttaggca agtgtctctg
    39361 gttacgacgt catggactct aaatcgatta tatttagggg tcatgactag tgaagcagtt
    39421 agctagttcg catataagcg gctagcgtct aacaattagg aactttagtt ccaataactt
    39481 taagattacg acgttttagg acataaatcg atcatattta tgtcctaaaa ctagtgaagc
    39541 gcctagccaa agtccgaata ggatttggcg ttagttactt agattgcttt gcaatcaagt
    39601 aactttggcg atttacatct tctctggcgc ttctactcca agcaagcgaa gggcttcttt
    39661 gagaacgact gcggttgcgt agctgagggc tagacggctg tcgcgttctg ggctttcatc
    39721 caagatacgt gtatgtgcat agtatttgtt aaaggattga gccaggctaa ttgcaaattt
    39781 agcaatgata gaaggttcaa agttatctgc cgcacggttg ataatacgtg ggaagtcttg
    39841 aatgagttta atgatttccc agctttcagt atcattcaag ctatagttgc cagctgtttc
    39901 tggtttgaaa tcggctttgc gtaagataga ttggatacga gcgtaggcat attgaacgta
    39961 aggtccagtt tcaccctcga aggataccat agcctctagg tcgaagtcgt atccatttgt
    40021 acggtcggtt ttgaggtcat agaatttaat ggctccaatc ccaacagcat gtgctacttg
    40081 gtctttgttt tctagttcag gatttttagc ctcgatttgg accttggcac ggctaacagc
    40141 ctctgcaaca gtaggctcta gcaagatgac attcccttta cgagtagaga gtttcttccc
    40201 ttcttttgta accaaaccaa aaggaacgtg agtaatgtcg tcactccagt cgtagcccat
    40261 ctcttgcaag acagctttga gctgtttaaa gtgggcagat tgttcttgac caacgacata
    40321 gatagattta gcaaattggt attcgttttt acggtagagg gctgcagcca agtcacgtgt
    40381 gatatagaga gttgcaccat cagacttctt gatgagggct ggatgttcaa ttccatattt
    40441 ctcaagattc acaacttggg caccttctga ttcaagaagt agtccttttt cagaaagaat
    40501 gtctacaact gcatccatct tatcattgta gaaggcttct ccgttatagc tgtcaaattc
    40561 aaccttcaat tcattgtaaa ggcggttaaa ttccactaaa ctttcatcgc ggaaccattg
    40621 ccaaagagcg agagcttcct catctccatt ttcaagttta cggaaccatt cgcgcgcttc
    40681 ttcatccaag ctagggtcat tttcagcttc agcgttgatg cggacataga gtttaaggag
    40741 ttcatcgatt ggatgagctt ttacagcttc ttcgtcgccc cattttttgt aggcaacaat
    40801 caacatccca aattgtttac cccagtctcc caaatggttg accttgaccg tttgataacc
    40861 gattttttgg aaaatatgtg acaagctatc tccgataaca gttgaacgca ggtggccaat
    40921 agaaaatggt ttagcgatat tcggactaga catgtcgata acaacatttt cttgtttacc
    40981 aatattttgg tcagcatagt gttctttttc agtggtaaca gcttgcaata cttgagcaga
    41041 aatggcagat ttatcaagga aaaagttaac gtaaggtcct gttgcgacaa ctttttcaaa
    41101 ggcttggctg ttcatttttt cagccagttc agccgcaatc atttgtggtg ctttacgttc
    41161 gacttttgca agagaaaaag cagggaaagc aatgtctccc atttctgagt ttttaggggt
    41221 ttccagtaac tttaaaatag cctcttggtc caggctatca atgatgctag ataattcgct
    41281 agcaatcaat tcttttgtat tcattaagag ctcctttttg gacttttcta ctattttatc
    41341 acaattttaa agaaagaaga aaaaattttt gaaatctcct gtttttttgg tataatatgg
    41401 ttataaatat agttataaat atgcacgcaa gaggatttta tgagaaaaag agatcgtcat
    41461 cagttaataa aaaaaatgat tactgaggag aaattaagta cacaaaaaga aattcaagat
    41521 cggttggagg cgcacaatgt ttgtgtgacg cagacaacct tgtctcgtga tttgcgcgaa
    41581 atcggcttga ccaaggtcaa gaaaaatgat atggtgtatt atgtactagt aaatgagaca
    41641 gaaaagattg atttggtgga atttttgtct catcatttag aaggtgttgc aagagcagag
    41701 tttaccttgg tgcttcatac caaattggga gaagcctctg ttttggcaaa tattgtagat
    41761 gtaaacaagg atgaatggat tttaggaaca gttgctggtg ccaatacctt attggttatt
    41821 tgtcgagatc agcacgttgc caaactcatg gaagatcgtt tgctagattt gatgaaagat
    41881 aagtaaggtc ttgggagttg ctctcaagac ttatttttga aaaggagaga cagaaaatgg
    41941 cgatagaaaa gttatcaccc ggcatgcaac agtatgtgga tattaaaaag caatatccag
    42001 atgctttttt gctctttcgg atgggtgatt tttatgaatt attttatgag gatgcggtca
    42061 atgctgcgca gattctggaa atttccttaa cgagtcgcaa caagaatgcc gacaatccga
    42121 tccctatggc gggtgttccc tatcattctg cccaacagta tatcgatgtc ttgattgagc
    42181 agggttataa ggtggctatc gcagagcaga tggaagatcc taaacaagca gttggggttg
    42241 ttaaacgaga ggttgttcag gtcattacgc cagggacagt ggtcgatagc agtaagccgg
    42301 acagtcagaa taattttttg gtttccatag accgcgaagg caatcaattt ggcctagctt
    42361 atatggattt ggtgacgggt gacttttatg tgacaggtct tttggatttc acgctggttt
    42421 gtggggaaat ccgtaacctc aaggctcgag aagtggtgtt gggttatgac ttgtctgagg
    42481 aagaagaaca aatcctcagc cgccagatga atctggtact ctcttatgaa aaagaaagct
    42541 ttgaagacct tcatttattg gatttgcgat tggcaacggt ggagcaaacg gcatctagta
    42601 agctgctcca gtatgttcat cggactcaga tgagggaatt gaaccacctc aaacctgtta
    42661 tccgctacga aattaaggat ttcttgcaga tggattatgc gaccaaggct agtctggatt
    42721 tggttgagaa tgctcgctca ggtaagaaac aaggcagtct tttctggctt ttggatgaaa
    42781 ccaaaacggc tatggggatg cgtctcttgc gttcttggat tcatcgcccc ttgattgata
    42841 aggaacgaat cgtccaacgt caagaagtag tgcaggtctt tctcgaccat ttctttgagc
    42901 gtagtgactt gacagacagt ctcaagggtg tttatgacat tgagcgcttg gctagtcgtg
    42961 tttcttttgg caaaaccaat ccaaaggatc tcttgcagtt ggcgactacc ttgtctagtg
    43021 tgccacggat tcgtgcgatt ttagaaggga tggagcaacc tactctagcc tatctcatcg
    43081 cacaactgga tgcaatccct gagttggaga gtttgattag cgcagcgatt gctcctgaag
    43141 ctcctcatgt gattacagat gggggaatta tccggactgg atttgatgag actttagaca
    43201 agtatcgttg cgttctcaga gaagggacta gctggattgc tgagattgag gctaaggagc
    43261 gagaaaactc tggtatcagc acgctcaaga ttgactacaa taaaaaggat ggctactatt
    43321 ttcatgtgac caattcgcaa ctaggaaatg tgccagctca ctttttccgc aaggcgacgc
    43381 tgaaaaactc agaacgcttt ggaaccgaag aattagcccg tatcgaggga gatatgcttg
    43441 aggcgcgtga gaagtcagcc aacctcgaat acgaaatatt tatgcgcatt cgtgaagagg
    43501 tcggcaagta catccagcgt ttacaagctc tagcccaagg aattgcgacg gttgatgtct
    43561 tacagagtct ggcggttgtg gctgaaaccc agcatttgat tcgacctgag tttggtgacg
    43621 attcacaaat tgatatccgg aaagggcgcc atgctgtcgt tgaaaaggtt atgggggctc
    43681 agacctatat tccaaatacg attcagatgg cagaagatac cagtattcaa ctggttacag
    43741 ggccaaacat gagtgggaag tctacctata tgcgtcagtt agccatgacg gcggttatgg
    43801 cccagctggg ttcctatgtt cctgctgaaa gcgcccattt accgattttt gatgcgattt
    43861 ttacccgtat cggagcagca gatgacttgg tttcgggtca gtcaaccttt atggtggaga
    43921 tgatggaggc caataatgcc atttcgcatg cgaccaagaa ctctctcatt ctctttgatg
    43981 aattgggacg tggaactgca acttatgacg ggatggctct tgctcagtcc atcatcgaat
    44041 atatccatga gcacatcgga gctaagaccc tctttgcgac ccactaccat gagttgacta
    44101 gtctggagtc tagtttacaa cacttggtca atgtccacgt ggcaactttg gagcaggatg
    44161 ggcaggtcac cttccttcac aagattgaac cgggaccagc tgataaatcc tacggtatcc
    44221 atgttgccaa gattgctggc ttgccagcag accttttagc aagggcggat aagattttga
    44281 ctcagctaga gaatcaagga acagagagtc ctcctcccat gagacaaact agtgctgtca
    44341 ctgaacagat ttcactcttt gatagggcag aagagcatcc tatcctagca gaattagcta
    44401 aactggatgt gtataatatg acacctatgc aggttatgaa tgtcttagta gagttaaaac
    44461 agaaactata aaaccaagac tcactagtta atctagctgt atcaaggaga cttctttgac
    44521 aattctccac ttttttgcta gaataacatc acacaaacag aatgaaaagg agctgacgca
    44581 ttgtcgctcc cttttgtcta ttttttaagg agaaagtatg ctgattcaga aaataaaaac
    44641 ctacaagtgg caggccctgg cttcgctcct gatgacaggc ttgatggttg ctagttcact
    44701 tctgcaaccg cgttatctgc aggaagtctt aggcgccctc cttactggga aatatgaagc
    44761 tatttatagt atcggggctt ggttgattgg tgtggccgta gtcggtctag ttgctggtgg
    44821 actcaatgtt gtcctcgcag cctatattgc ccaaggagtt tcatccgacc ttcgggagga
    44881 tgccttccgt aaaattcaaa ccttttctta tgctgatatt gaacaattta atgcgggaaa
    44941 tctagtcgtt cgaatgacaa atgatatcaa ccagattcag aacgttgtca tgatgacctt
    45001 ccaaattctt ttcagacttc ccctcttgtt catcggttcg tttatcctag cggttcaaac
    45061 cttaccttct ctgtggtggg tgattgttct catggtagtc ttgatttttg gtttgactgc
    45121 tgtcatgatg ggaatgatgg ggcctcgttt tgccaagttt caaacccttc ttgagcgcat
    45181 caatgccatt gccaaggaaa atttacgtgg cgttcgtgtg gtcaagtcct ttgtccaaga
    45241 aaaagagcaa tttgctaagt ttacagaggt ctcagacgag cttcttggtc aaaaccttta
    45301 cattggttat gccttttcag tagtggaacc ctttatgatg ttggttggtt acggggcggt
    45361 cttcctctct atttggctgg tcgcgggaat ggttcagtcg gatccgtctg ttgttggttc
    45421 catcgcttct tttgttaatt acctaagcca gattatcttt accattgtta tggttggatt
    45481 tttgggaaat tctgtcagcc gtgccatgat ttccatgcgt cgtattcgag aaattcttga
    45541 cgcagagcca gctatgacct tcaaggatat cccagatgaa gagttggttg gaagtcttag
    45601 ctttgaaaat gtgaccttta cctatccaat ggacaaggaa ccgatgctga aagatgtgag
    45661 ctttactatt gaacctggtc aaatggttgg tgtagttgga gcgactggtg caggaaagtc
    45721 aaccttggct caattgattc cacgtctctt tgatccacag gacggggcca ttaaaatcgg
    45781 tggcaaggat attcgagaag tgagtgaagg aaccctgcgt aaaacagttt ccatcgttct
    45841 ccaacgtgcc attcttttta gtggaacgat tgcagataac ttgagacagg ggaaggggaa
    45901 tgctactcta tttgaaatgg agcgcgcagc caatattgcc caggctagtg aattcattca
    45961 tcgtatggag aaaacctttg aaagtccagt tgaagaacgg ggaaccaatt tctctggtgg
    46021 acaaaaacaa aggatgtcga ttgcgcgtgg gattgtcagc aatccacgta ttctgatttt
    46081 tgatgattcg acctcagcct tggatgccaa atcagagcgc ttggtgcaag aagctttgaa
    46141 taaggacttg aaggggacga caaccattat tattgctcaa aaaattagct cggttgtcca
    46201 tgcagacaag atcttggttc taaatcaagg acgattgatt ggtcaaggta cgcatgcaga
    46261 cttggttgcc aacaatgccg tttaccgtga aatctatgaa acacagaaat gaaagacaaa
    46321 ctataagaaa agtcaatagt tttatctaaa ctatttctta tttcaatttg atgatttggc
    46381 gatgatttta gagcacggca aaaagccctt gaaaaagtcc attttttcaa aggtaatcct
    46441 gtgttaattt cagaaattac atcacttttt gttcgtcaaa tggcagctct ttttttagga
    46501 tataaaacag ggttcggata agtttttttg caaggtggat gatggctaca ttgtaatgtt
    46561 ttccttgttc taatttagtc ttaagatagg ccttaaaagc aggcgaaaag cgagggcatg
    46621 ctttggcagc ttgtatgagt acctaccgca gatgagggga actccgtttg accattcttc
    46681 ctgctaaatc aatctgatct gactgataaa tagaagaatc cagtccagcg aaagcttgta
    46741 attgagcagg attatcaaag gcatgaatat ttcgaatctc agctaaaatg accgccccta
    46801 aacgatcccc aatcccagta accgtcgtga tgaccgagtt gaactcagcc atcaagtcat
    46861 tgacacatgt ttccgccttg tcaatgagcc tcttgtaatg tttgatgttt tcattacacg
    46921 agataaaacg tctatgcgtt atcaaactca ttaccaatta aaacaaaaag ctgtggttag
    46981 atcctttcgg aaattgtcaa gcgattggag gaaatgaact aatccacagc ggcttattcc
    47041 aagtatacca cttgggcttt ggcagtagct aactgcgcta aatataatat aaggaggagt
    47101 aaaatgaaga cagttcaatt tttttggcat tattttaagg tctacaagtt ctcatttgta
    47161 gttgtcatcc tgatgattgt tctggcgact tttgcccaag ccctctttcc agtcttttct
    47221 ggacaagcgg tgacgcagct agccaattta gttcaagctt atcaaaatgg caatccagaa
    47281 cttgtatggc aaagcctatc aggaatcatg gtcaatcttg gcctgctggt tttggttcta
    47341 tttatctcta gtgtaatata catgtgtctc atgacgcgcg tgattgcaga atcgaccaac
    47401 gagatgcgca aaggcctctt tggtaagctt gctcagttga cggtttcttt ctttgaccgt
    47461 cgacaagatg gcgatatcct gtctcatttt accagtgatt tggataatat cctccaagcc
    47521 tttaacgaaa gcttgattca ggtcatgagc aatattgttt tatacattgg tctgattctt
    47581 gtcatgtttt cgagaaatgt gacgctggct ctcatcacca ttgccagcac cccattggct
    47641 ttccttatgc tgattttcat cgtgaaaatg gcacgcaaat acaccaacct ccagcagaaa
    47701 gaggtaggga agctcaacgc ctatatggat gagagcatct caggccaaaa agccgtgatt
    47761 gtgcaaggaa ttcaagagga tatgatggca ggatttcttg aacaaaatga gcgcgtgcgc
    47821 aaggcaacct ttaaaggaag aatgttctca ggaattcttt tccctgtcat gaatgggatg
    47881 agcctgatta atacagccat cgtcatcttt gctggttcgg ctgtactttt gaatgataag
    47941 tctattgaaa caagtacagc cctaggtttg attgttatgt ttgcacaatt ttcacagcag
    48001 tactaccagc ctattatcca agttgcagcg agttggggaa gccttcagtt ggcctttact
    48061 ggagctgaac gaattcagga aatgtttgat gcagaggagg aaatccgacc tgaaaaggct
    48121 ccaaccttca ctaagttgca agaaagtgtt gaaatcagtc atatcgtttt ttcatacttg
    48181 cctgataaac ctattttgaa agatgtcagc atttctgccc ctaaaggcca gatgacagca
    48241 gttgttgggc cgacaggttc aggaaaaacg actattatga acctcatcaa tcgcttttat
    48301 gatgttgatg ctggtggtat ttattttgat ggtaaagaca ttcgtggcta tgacttagat
    48361 agtcttagaa gcaaggtggg aattgtattg caagattcgg tcttgtttag cggaacgatt
    48421 agagacaata tccgatttgg tgtgccagat gctagtcagg aaatggttga ggtagcagca
    48481 aaagcaaccc acattcacga ctatatcgaa agtttgcctg ataagtacga tactcttatt
    48541 gatgatgacc agagcatctt ttcaacaggg cagaagcaat tgatttcaat cgctcgaacc
    48601 ctgatgacag atccagaagt tctcattctc gatgaagcaa cttcaaacgt agatacggtg
    48661 acagaaagca agattcagca tgccatggag gtggttgtag caggtagaac tagtttcgtc
    48721 attgcccacc gcttgaaaac cattctcaat gcagatcaga ttattgtcct taaagatgga
    48781 gaagtcattg aacgtggtaa ccaccatgaa cttttgaagc taggtggctt ttattcagaa
    48841 ctctatcaca atcaatttgt tttcgaataa gaaagaagtt gtcctatgtg ggcagctttt
    48901 tcttgtccat aaaaaatgtt tatcacagcc ttaaaaaaaa catattagac gaaagtcatt
    48961 ttgagtgata tgataggact atcgttagca ttcgaaagga gaggcatcat ggctagaacg
    49021 gttgtaggag ttgctgcaaa tctatgtccc gtagacgcag aaggcaaaat cattcattca
    49081 tctgtatctt gtagattcgc agagatcatt cgtcaagtcg gtggtctccc tttagtcatt
    49141 cctgttggtg atgagtcagt tgtacgtgat tatgtggaaa tgattgacaa actcattttg
    49201 acaggaggcc aaaatgttca tcctcagttt tatggagaga aaaagaccgt cgagagcgat
    49261 gattacaatc tggtccgtga cgaatttgaa ttggcactct tgaaggaagc gcttcgtcag
    49321 aataaaccaa ttatggcaat ctgtcgcggt gtccaacttg tcaatgttgc ctttggtgga
    49381 accctcaatc aagaaatcga aggtcactgg caaggactac ctttcgggac atctcactct
    49441 attgagacag tagaaggaag cgtggtggct aagctatttg ggaaagaaag tcaggtcaac
    49501 tcagtccatc gtcaaagcat taaagatttg gcacctaatt tccgtgtaac tgctattgat
    49561 tcaagagacc aaactattga agcgattgag tctatcgacg agcaccgcat tatcggttta
    49621 cagtggcatc cagagtttct ggttaatgaa gaagatggca atttagaatt atttgagtat
    49681 ttattgaatg aactgtaacg attggaacat ctggtcgttc tttcttttat tttttcaaaa
    49741 tttttagaat gtggcatttt acgcaaacgt ttgaattctg ataaaaattg gagaaattcg
    49801 acaaaaaaac ttgaaaaaaa cgaaggtaag cgttatgata gaaaagaaga aatattggag
    49861 gaagaacatg tcacatatta aatttgatta ttcaaaagtt ttagacaaat ttgttgcacc
    49921 acatgaagtg gaatacatgc aatcacaagt aacagcagca gatgaattaa tccgtaaagg
    49981 aactggtgct ggtagcgact tcttgggatg gttggacctt cctgaaaaat acgaccgcga
    50041 agaatttgac cgcatcttga aagctgctga gcaaatcaag tcagacagcg atgttttggt
    50101 tgtgatcggt attggtggat cttaccttgg tgcaaaagca gcaatcgact tcttgaatca
    50161 ccattttgct aacttgcaaa caaaagaaga acgcaaagct ccacaaatcc tttacgcagg
    50221 aaactcaatc tcatctactt accttgctga cttggtagag tatgttgcag acaaagactt
    50281 ctcagtaaac gtaatttcta aatcaggtac aacaactgaa ccagcgattg ctttccgtgt
    50341 ctttaaagaa ctcttggtta agaaatacgg tcaagaagaa gctaacaaac gtatctatgc
    50401 aacaactgac cgccaaaagg gtgctgttaa ggttgaagca gacgctaacg gttggggaac
    50461 atttgttgtt ccagatgata tcggtggacg cttctcagta ttgacagccg ttggtttgct
    50521 ttcaatcgca gcatcaggag ctgacataaa agctcttatg gaaggtgcga atgcagctcg
    50581 caaagactac acttcagaca aaatctctga aaacgaagct taccaatacg cagctgttcg
    50641 taacatcctt tatcgtaaag gctatgcaac tgagatcttg gtaaactatg agccatcact
    50701 tcaatacttc tcagaatggt ggaaacaatt ggctggtgaa tcagaaggaa aagaccaaaa
    50761 aggtatctac ccaacttcag ccaacttctc aactgacttg cactcacttg gtcaatttat
    50821 ccaagaagga actcgtatca tgtttgaaac agttgtccgt gttgacaaac ctcgtaaaaa
    50881 cgtgcttatt cctactttgg aagaagacct tgacggactt ggttaccttc aaggaaaaga
    50941 cgttgacttt gtaaacaaaa aagcaactga cggtgttctt cttgcccaca cagatggtga
    51001 tgtaccaaac atgtatgtga ctcttccaga gcaagacgct ttcactcttg gttacactat
    51061 ctacttcttc gaattggcaa ttgccctttc aggttacttg aatgctatca acccatttga
    51121 ccaaccaggt gttgaagctt ataaacgtaa catgtttgcc cttcttggaa aaccaggatt
    51181 tgaagaattg agcaaagaac ttaacgcacg tctataatag aagaaaagag tggtttgccc
    51241 actcttttta ctctctttat ccatagaaat tggactcagc caagacttgt gatataatat
    51301 agaaagcaaa aaggcagacg cctagataat aggagaaact atgtcaaaag atatccgcgt
    51361 acgttacgca ccaagtccaa caggactact acacatcgga aatgctcgta cagcattgtt
    51421 taattacttg tatgcgcgcc atcatggtgg aacatttctc atccgtatcg aagatactga
    51481 ccgtaaacgc catgtcgagg atggtgaacg ttcacaactt gaaaaccttc gctggttagg
    51541 catggattgg gatgaaagtc cagaatcaca tgagaattat cgccagtctg agcgtttgga
    51601 cttgtatcaa aaatatattg accaactatt agctgaagga aaagcctata aatcttacgt
    51661 tacagaagaa gagttggcag ctgaacgcga acgccaagaa gtagctggcg aaacaccacg
    51721 ctacatcaat gaataccttg gtatgagtga agaagaaaaa gcagcttaca tcgcagaacg
    51781 tgaagcagca gggatcatcc caactgttcg tttggctgtc aatgagtcag gtatctacaa
    51841 gtggcatgat atggtcaaag gcgatatcga atttgaaggt ggcaatatcg gtggtgactg
    51901 ggttatccaa aagaaagacg gttacccaac ttacaacttt gccgttgtta tcgatgacca
    51961 cgatatgcaa atctctcatg ttatccgtgg agatgaccat attgctaata caccaaaaca
    52021 gcttatggtc tatgaagctc ttggttggga agctccagag ttcggtcaca tgaccttgat
    52081 tatcaactct gaaactggta agaagttatc taaacgtgat actaatacac ttcaatttat
    52141 cgaagattac cgaaagaaag gttaccttcc agaagcagtc tttaacttta ttgctcttct
    52201 tggttggaac ccaggtggtg aagatgagat tttctctcgt gaagaattca ttaaactttt
    52261 tgatgaaaac cgcctcagca agtcaccagc agcctttgat cagaaaaaac tagactggat
    52321 gagcaatgat tatatcaaga atgcagacct tgaaaccatc tttgaaatgg caaaaccatt
    52381 cttagaggaa gcaggccgtt tgactgacaa ggctgaaaaa ttagttgagc tctataaacc
    52441 acaaatgaaa tcagtagatg agattatccc attgacagat cttttcttct cagatttccc
    52501 agaattgaca gaagcagagc gcgaagtcat gacgggtgaa acagttccaa cagttcttga
    52561 agcattcaaa gcaaaacttg aagcgatgac agatgatgaa tttgtgacag aaaatatctt
    52621 cccacaaatt aaagcagtcc aaaaagaaac aggtattaaa gggaaaaatc ttttcatgcc
    52681 tattcgtatc gcagtttcag gcgaaatgca tgggccagaa ttaccagata caattttctt
    52741 gcttggacgt gaaaaatcaa ttcagcatat cgaaaacatg ctaaaagaaa tctctaaata
    52801 aagaggatac aataatggac atctgggaaa agatgtacga agaagcacag aaactataca
    52861 atccacatga agtatcagac tttgtttatg ccaatcatgt tgtagctgca gtagaagcag
    52921 gagatggaca aatatttaca ggattctgta tggagggaac ctgtggtgtt ttccatctct
    52981 gcgcagaacg ggcggccctc ttcaatatgt accaattttc aggacaaact aaggttaaga
    53041 aagtattagc ctttcgagac aaaccacctt atggtggaag ttcagccatg ccttgcggtg
    53101 cttgtagaga attcctttta gagcttaatg ctgaaaataa agatgcagaa ttcatgatgg
    53161 actataatat aagaaaaaca gttaaagtcg cagaactaat cccttattgg tggggaaaag
    53221 aacgtgcttc taagtttaat gagcgataga agagtcagta taattctggc tttttttact
    53281 ataagttgaa aaaataaaaa aaaattagaa aaagtagttg acaaagtttg aaaag
//
LOCUS       DAVFER010000013        48811 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1105170250
            SAMEA2167659-rid19724873.denovo.013, whole genome shotgun sequence.
ACCESSION   DAVFER010000013 DAVFER010000000
VERSION     DAVFER010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2167659
            Sequence Read Archive: ERR388902
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 48811)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 48811)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928716.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928716.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 04:07:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,118
            CDSs (total)                      :: 2,073
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 120
            CDSs (without protein)            :: 120
            Pseudo Genes (ambiguous residues) :: 0 of 120
            Pseudo Genes (frameshifted)       :: 67 of 120
            Pseudo Genes (incomplete)         :: 47 of 120
            Pseudo Genes (internal stop)      :: 34 of 120
            Pseudo Genes (multiple problems)  :: 23 of 120
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..48811
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2167659-rid19724873.denovo.013"
                     /strain="1105170250"
                     /db_xref="taxon:1313"
     gene            5..75
                     /locus_tag="VU534_000744"
     tRNA            5..75
                     /locus_tag="VU534_000744"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:37..39,aa:Gly,seq:tcc)
     gene            110..183
                     /locus_tag="VU534_000745"
     tRNA            110..183
                     /locus_tag="VU534_000745"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:144..146,aa:Ile,seq:gat)
     gene            266..355
                     /locus_tag="VU534_000746"
     tRNA            266..355
                     /locus_tag="VU534_000746"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:302..304,aa:Ser,seq:tga)
     gene            366..439
                     /locus_tag="VU534_000747"
     tRNA            366..439
                     /locus_tag="VU534_000747"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:400..402,aa:Met,seq:cat)
     gene            443..515
                     /locus_tag="VU534_000748"
     tRNA            443..515
                     /locus_tag="VU534_000748"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:476..478,aa:Phe,seq:gaa)
     gene            528..608
                     /locus_tag="VU534_000749"
     tRNA            528..608
                     /locus_tag="VU534_000749"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:562..564,aa:Tyr,seq:gta)
     gene            613..683
                     /locus_tag="VU534_000750"
     tRNA            613..683
                     /locus_tag="VU534_000750"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:645..647,aa:Trp,seq:cca)
     gene            698..770
                     /locus_tag="VU534_000751"
     tRNA            698..770
                     /locus_tag="VU534_000751"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:731..733,aa:His,seq:gtg)
     gene            781..852
                     /locus_tag="VU534_000752"
     tRNA            781..852
                     /locus_tag="VU534_000752"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:813..815,aa:Gln,seq:ttg)
     gene            862..945
                     /locus_tag="VU534_000753"
     tRNA            862..945
                     /locus_tag="VU534_000753"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:896..898,aa:Leu,seq:caa)
     gene            1052..2329
                     /locus_tag="VU534_000754"
     CDS             1052..2329
                     /locus_tag="VU534_000754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001277926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--cysteine ligase"
                     /protein_id="HEU1513368.1"
                     /translation="MSCSIDLLKHRYLKNIKENPELFVGIELEYPVASLEGDATDVEV
                     MKDLFHYLVSTLDLTVAKVDDFGNLIQLVDPISQDAILFEVSYTTIEFAFGKAETIQE
                     VENRFNNYMNVIQRKLAESNHAIVGCGIHPNWDKNENCPVAYPRYQMLMDYLNLSRNI
                     IKSDLHHFPEYGTFICGSQVQLDISKTNYLRVINAFTQIEAAKAYLFANSEFSGADWD
                     TKISRDIFWEESMHGIYPENVGVNARLLNDETDFFDYLNHSAIFTAERDGQTYYFYPI
                     QAGDYLATSEIQAFALNGDEVIIYPQEKDFETHRSYQYQDLTTRGTVEFRSVCTQPLD
                     RTFASAAFHLGLLVNLDKLEAYLETAPFFKVFGYDYKSLRRQFSKKNLTDEEETTIIE
                     FSKDLLLLAEEGLVVRNKEEMTYLQPLREELSL"
     gene            2405..3889
                     /locus_tag="VU534_000755"
     CDS             2405..3889
                     /locus_tag="VU534_000755"
                     /EC_number="4.2.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006595200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine synthase"
                     /protein_id="HEU1513369.1"
                     /translation="MTLVYQSTRDANNTVTASQAILQGLATDGGLFTPDTYPKVDLNF
                     DKLKDASYQEVAKLVLSAFLDDFTVEELDYCINNAYDSKFDTPAIAPLVKLDGQYNLE
                     LFHGSTIAFKDMALSILPYFMTTAAKKHGLENKIVILTATSGDTGKAAMAGFANVPGT
                     EIIVFYPKDGVSKIQELQMTTQTGDNTHVIAIDGNFDDAQTNVKHMFNDVALREKLTT
                     NKLQFSSANSMNIGRLVPQIVYYVYAYAQLVKTGEIVAGEKVNFTVPTGNFGNILAAF
                     YAKQIGLPVGKLICASNDNNVLTDFFKTRVYDKKREFKVTTSPSMDILVSSNLERLIF
                     HLLGNNAEKTTELMNALNTQGQYKLTDFDAEILDLFAAEYATEEETAAEIKRVCELDS
                     YIEDPHTAVASAVYKKYQSATGDVTKTVIASTASPYKFPVVAVEAVTGKAGLTDFEAL
                     AQLHEISGVAVPPAVDGLEIAPIRHKTTVAAADMQAAVEAYLGL"
     gene            3950..5230
                     /locus_tag="VU534_000756"
     CDS             3950..5230
                     /locus_tag="VU534_000756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000473957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HEU1513370.1"
                     /translation="MFKKNKDILNIALPAMGENFLQMLMGMVDSYLVAHLGLIAISGV
                     SVAGNIITIYQAIFIALGAAISSVISKSIGQKDQSKLAYHVTEALKITLLLSFLLGFL
                     SIFAGKEMIGLLGTERDVAESGGLYLSLVGGSIVLLGLMTSLGALIRATHNPRLPLYV
                     SFLSNALNILFSSLAIFVLDMGIAGVAWGTIVSRLVGLVILWSQLKLPYGKPTFGLDK
                     ELLTLALPAAGERLMMRAGDVVIIALVVSFGTEAVAGNAIGEVLTQFNYMPAFGVATA
                     TVMLLARAVGEDDWKRVASLSKQTFWLSLFLMLPLSFSIYVLGVPLTHLYTTDSLAVE
                     ASVLVTLFSLLGTPMTTGTVIYTAVWQGLGNARLPFYATSIGMWCIRIGTGYLMGIVL
                     GWGLPGIWAGSLLDNGFRWLFLRYRYQRYMSLKG"
     gene            5234..5854
                     /locus_tag="VU534_000757"
     CDS             5234..5854
                     /locus_tag="VU534_000757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001172828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEU1513371.1"
                     /translation="MQKTAFIWDLDGTLLDSYEAILSGIEETFAQFSIPYDKEKVREF
                     IFKYSVQDLLVRVAEDRNLDVEVLNQVRAQSLAEKNAQVVLMPGAREVLAWADESGIQ
                     QFIYTHKGNNAFTILKDLGVESYFTEILTSQSGFVRKPSPEAATYLLDKYQLNSDNTY
                     YIGDRTLDVEFAQNSGIQSINFLESTYEGNHRIQALADISRIFETK"
     gene            6020..7132
                     /locus_tag="VU534_000758"
     CDS             6020..7132
                     /locus_tag="VU534_000758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HEU1513372.1"
                     /translation="MKKRMLLASTVALSFAPVLATQAEEVLWTARSVEQIQNDLTKTD
                     NKTSYTVQYGDTLSTIAEALGVDVTVLANLNKITNMDLIFPETVLTTTVNEAEEVTEV
                     EIQTPQADSSEEVTTATADLTTNQVTVDDQTVQVADLSQPIAEVTKTVIASEEVAPST
                     GTSVPEEQTTETTRPVEEATPQETTPAEKQETQASPQAASAVEVTTTSSEAKEVASSN
                     GATAAVSTYQPEETKIISTTYEAPAAPDYAGLAVAKSENAGLQPQTAAFKEEIANLFG
                     ITSFSGYRPGDSGDHGKGLAIDFMVPERSELGDKIAEYAIQNMASRGISYIIWKQRFY
                     APFDSKYGPANTWNPMPDRGSVTENHYDHVHVSMNG"
     gene            7455..7880
                     /locus_tag="VU534_000759"
     CDS             7455..7880
                     /locus_tag="VU534_000759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000890080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HEU1513373.1"
                     /translation="MLEIQDLLYQLRLSEQASTQLFEKRLGISLTRYQILLFLLEHSP
                     CNQMAVQERLKIDQAALTRHFKILETEGLVERHRNPENQREVLVEAAKYAKEQLVVNP
                     PLQHIRVKEEIESILTEFERTELSRLLNKLVLGIENIEI"
     gene            7891..8250
                     /locus_tag="VU534_000760"
     CDS             7891..8250
                     /locus_tag="VU534_000760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1304 domain-containing protein"
                     /protein_id="HEU1513374.1"
                     /translation="MSIILTTIVALEHFYIFYLESIATQSDATSRVFNMEKEELAHPS
                     VSSLFKNQGIYKALLGVFLLYVIYFSQNLEIVTIFVLFVIGAATYGSLTADKKIILKQ
                     GGSAILALISILLFKYT"
     gene            8357..9001
                     /gene="pcp"
                     /locus_tag="VU534_000761"
     CDS             8357..9001
                     /gene="pcp"
                     /locus_tag="VU534_000761"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HEU1513375.1"
                     /translation="MKVLVTGFEPFGGEKGNPALEAIKGLPAEIHGAEVRWLEVPTVF
                     HKSAQVLEEEMNRYQPDFVLCIGQAGGRTSLTPERVTINQDDACISDNEDNQPIDRPI
                     RPDGASAYFSSLPIKAMVQAIKKEGLPASVSNTAGTFVCSHLMYQALYLVEKKSPYVK
                     AGFMHIPYMMEQVVNRPTTPAMSLVDIRRGIEAAIGAIIEHGDQELKLVGGETH"
     gene            complement(9029..9886)
                     /locus_tag="VU534_000762"
     CDS             complement(9029..9886)
                     /locus_tag="VU534_000762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HEU1513376.1"
                     /translation="MNYPKIDLKTIRQESKHFQADTPRLFLLYILPSMLVILSGFLNP
                     LSRIHGTVLEQPFFSILGQILQTYLFPLLVSFIGTILLTSSVYATLTLMKDSKTEPSV
                     KNSLALFDEERFSQTFLTLLLKRFYLFLWSIPNLLGIYLLFYSSFLAKKFVTLHPEFP
                     NLDLSSVETERFLMVFGLYFLASLILIIVGNILYIPQYYAYSQVEFLLCYSLDLGQVP
                     PRRILKTSRSFMKGYKFQHFVLDLQLLPWYFLNWITFGIASFSLLPYIQCTKIMFYRA
                     VLARKRPKA"
     gene            10016..11158
                     /gene="tgt"
                     /locus_tag="VU534_000763"
     CDS             10016..11158
                     /gene="tgt"
                     /locus_tag="VU534_000763"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004298827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HEU1513377.1"
                     /translation="MSDSPIKYRLIKKEKHTGARLGEIITPHGTFPTPMFMPVGTQAT
                     VKTQSPEELKEMGSGIILSNTYHLWLRPGDELIARAGGLHKFMNWDQPILTDSGGFQV
                     YSLADSRNITEEGVTFKNHLNGSKMFLSPEKAISIQNNLGSDIMMSFDECPQFYQPYD
                     YVKKSIERTSRWAERGLKAHRRPHDQGLFGIVQGAGFEDLRRQSAHDLVSMDFSGYSI
                     GGLAVGETHEEMNAVLDFTTQLLPENKPRYLMGVGAPDSLIDGVIRGVDMFDCVLPTR
                     IARNGTCMTSQGRLVVKNAQFAEDFTPLDPECDCYTCNNYTRAYLRHLLKADETFGIR
                     LTSYHNLYFLLNLMKQVRQAIMDDNLLEFREYFVEKYGYNKSGRNF"
     gene            11256..13073
                     /locus_tag="VU534_000764"
     CDS             11256..13073
                     /locus_tag="VU534_000764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001220923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HEU1513378.1"
                     /translation="MRIKWFSLIRIIGLLLVLLYHFFQTIFPGGFFGVDVFFTFSGFL
                     ITALLIEEFSKNNEIDLIGFFRRRFYRIVPPVVLMVLVTMPFTFLVRQDYVAGIGGQI
                     AGVLGFMTNFYELLTGGSYESQFIPHLFVHNWSLAVEVHYYILWGLAVWFLSKQAKSN
                     GQLKGMVFLLSAVAFLISFFSMFIGSFLVTSYSSVYFSSLTHVYPFFLGSMLATIVGV
                     RQTTSLVKQLDKIWDLRKTLVVFGGGFGFLVLLTFFVKFTYLFAYLIGFLLASLAALA
                     MILAARVLHEKTHHIQESKIISFLADTSYAVYLFHWPFYIIFSQLTSNLLAVLLTLIC
                     SYGFASLSFYVLEPWIAGKNTPIVQTLRPLPYIHAILAAGTGILTIIVCTVTLLAPQV
                     GAFETDLTVNGLKQAATNIGQTKVMAERADANSLGIADGTMLIGDSVALRANTALQTA
                     LPGAQINAQVSVTTKTANEIMLNNSQNKFLPKTVVIATGVNNPENYKDDWDSIVKNLP
                     KGHHMILVTPYEGDKTKETYAIVEKAAAYMRELAEKTPYITIADWNQVAKEHPEIWAG
                     TDQVHFGSESSTIEAGAKLYADTIATALQTAQDKPVKSK"
     gene            13226..14377
                     /gene="nagA"
                     /locus_tag="VU534_000765"
     CDS             13226..14377
                     /gene="nagA"
                     /locus_tag="VU534_000765"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HEU1513379.1"
                     /translation="MPNYIKADQFFYPHGVRRGGYLELVDGKFGKHVEQIPEGAEVID
                     YTGYSIAPGLVDTHIHGYAGVDVMDNNIEGTLHTMSEGLLSTGVTSFLPTTLTATYEQ
                     LLAVTENLGNHYKEATGAKIRGIYYEGPYFTETFKGAQNPTYMRDPGVEEFHSWQKAA
                     NGLLNKIALAPERDGVEDFVRTVTGEGVTVALGHSNATFDEAKKAIDAGASVWVHAYN
                     GMRGLTHRELGMVGAMYQLPHTYAELICDGHHVDPKACEILIKQKGTENIALITDCMT
                     AGGLEDGDYMLGEFPVVVANGTARLKSTGNLAGSILKLKDGLKNVVEWGIANPHEAVM
                     MASFNPAKSVHIDDVCGQIREGYDADFIVLDKDLELVATYLDGVKRYQA"
     gene            14540..15598
                     /locus_tag="VU534_000766"
     CDS             14540..15598
                     /locus_tag="VU534_000766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent alcohol dehydrogenase family
                     protein"
                     /protein_id="HEU1513380.1"
                     /translation="MKAYTYVKPGLASFVDVDKPVIRKPTDAIVRIVKTTICGTDLHI
                     IKGDVPTCQSGTILGHEGIGIVEEVGEGVSNFKKGDKVLISCVCACGKCYYCKKGIYA
                     HCEDEGGWIFGHLIDGMQAEYLRVPHADNTLYHTPEDLSDEALVMLSDILPTGYEIGV
                     LKGKVEPGCSVAIIGSGPVGLAALLTAQFYSPAKLIMVDLDDNRLETALSFGATHKVN
                     SSDPEKAIKEIYDLTDGRGVDVAIEAVGIPATFDFCQKIIGVDGTVANCGVHGKPVEF
                     DLDKLWIRNINVTTGLVSTNTTPQLLKALESHKIEPEKLVTHYFKLSEIEKAYEVFSK
                     AADHHAIKVIIENDISEA"
     gene            15749..16114
                     /locus_tag="VU534_000767"
     CDS             15749..16114
                     /locus_tag="VU534_000767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1033 family protein"
                     /protein_id="HEU1513381.1"
                     /translation="MYRVIEMYGDFEPWWFLEGWEEDIVASRKFDQYYDALKYYKTCW
                     FRLEQESPLYKSRSDLMTIFWDPEDQRWCDECDEYLQQYHSLALLQDEQVIPDEKLRS
                     GYEKQTSQERNRSCRMKLK"
     gene            16190..17131
                     /locus_tag="VU534_000768"
     CDS             16190..17131
                     /locus_tag="VU534_000768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000249584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II/IV secretion system protein"
                     /protein_id="HEU1513382.1"
                     /translation="MVQEIAQEIIRSARKKGTQDIYFVPKLDAYELHMRVGDERCKIG
                     SYDFEKFAAVISHFKFVAGMNVGEKRRSQLGSCDYAYDHKIASLRLSTVGDYRGHESL
                     VIRLLHDEEQDLHFWFQDIEELGKQYRQRGLYLFAGPVGSGKTTLMHELSKSLFKGQQ
                     VMSIEDPVEIKQDDMLQLQLNEAIGLTYENLIKLSLRHRPDLLIIGEIRDSETARAVV
                     RASLTGATVFSTIHAKSIRGVYERLLELGVSEEELAVVLQGVCYQRLIGGGGIVDFAS
                     RDYQEHQAAKWNEQIDQLLKDGHITSLQAETEKISYS"
     gene            17079..18095
                     /locus_tag="VU534_000769"
     CDS             17079..18095
                     /locus_tag="VU534_000769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000355375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system F family protein"
                     /protein_id="HEU1513383.1"
                     /translation="MDISQVFRLRRKKLATAKQKNIITLFNNLFSSGFHLVETISFLD
                     RSALLDKQCVTQMRVGLSQGKSFSEMMESLGCSSAIVTQLSLAEVHGNLHLSLGKIEE
                     YLDNLAKVKKKLIEVATYPLILLGFLLLIMLGLRNYLLPQLDSSNIATQIIGNLPQIF
                     LGMVGLVSVLALLALTFYKRSSKMSVFSILARLPFIGIFVQTYLTAYYAREWGNMISQ
                     GMELTQIFQMMQEQGSQLFKEVGQDLAQTLKNGREFSQTIGTYPFFRKELSLIIEYGE
                     VKSKLGSELEIYAEKTWEAFFTRVNRTMNLVQPLVFIFVALIIVLLYAAMLMPMYQNM
                     EVNF"
     gene            18097..18423
                     /gene="comGC"
                     /locus_tag="VU534_000770"
     CDS             18097..18423
                     /gene="comGC"
                     /locus_tag="VU534_000770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="comG operon protein ComGC"
                     /protein_id="HEU1513384.1"
                     /translation="MKKMMTFLKKAKVKAFTLVEMLVVLLIISVLFLLFVPNLTKQKE
                     AVNDKGKAAVVKVVESQAELYSLEKNEDASLRKLQADGRITEEQAKAYKEYNDKNGGA
                     NRKVND"
     gene            18416..18820
                     /locus_tag="VU534_000771"
     CDS             18416..18820
                     /locus_tag="VU534_000771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HEU1513385.1"
                     /translation="MIKAFTMLESLLVLGLVSILALGLSGSVQSTFSAVEEQIFFMEF
                     EELYRETQKRSVASQQKTSLNLDGQTLSNGSQKLPVPKGIQAPSGQSITFDRAGGNSS
                     LAKVEFQTSKGAIRYQLYLGNGKIKRIKETKN"
     gene            18825..19085
                     /locus_tag="VU534_000772"
     CDS             18825..19085
                     /locus_tag="VU534_000772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000601743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1513386.1"
                     /translation="MILLEAVVALAIFASIATLLLGQIQKNRQEEAKILQKEEVLRVA
                     KMALQTGQNQVSINGVEIQVFSSEKGLEVYHGSEQLLAIKEP"
     gene            19048..19509
                     /locus_tag="VU534_000773"
     CDS             19048..19509
                     /locus_tag="VU534_000773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000250539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGF"
                     /protein_id="HEU1513387.1"
                     /translation="MVQNSCWQSKSHKVKAFTLLESLLALIVISGGLLLFQAMSQLLI
                     SEVRYQQQSEQKEWLLFVDQLEVELDRSQFEKVEGNRLYMKQDGKDIAIGKSKSDDFR
                     KTNARGRGYQPMVYGLKSVRITEDNQLVRFHFQFQKGLEREFIYRVEKEKS"
     gene            19487..19900
                     /locus_tag="VU534_000774"
     CDS             19487..19900
                     /locus_tag="VU534_000774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGF"
                     /protein_id="HEU1513388.1"
                     /translation="MWKKKKVKAGVLLYAVTIAAIFSLLLQFYLNRQVAHYQDYALNK
                     EKLVAFAMAKRTKDKVEQESGEQFFNLGQVSYQNKKTGLVTRVRTDKSQYEFLFPSVK
                     IKEEKRDKKEEVATDSSEKVEKKKSEEKPEKKENS"
     gene            20037..20631
                     /locus_tag="VU534_000775"
                     /pseudo
     CDS             20037..20631
                     /locus_tag="VU534_000775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000679792.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
     gene            20692..21645
                     /locus_tag="VU534_000776"
     CDS             20692..21645
                     /locus_tag="VU534_000776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000345081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEU1513389.1"
                     /translation="MDFEKIEQAYTYLLENVQVIQSDLATNFYDALVEQNSIYLDGET
                     ELNQVKENNQTLKRLALRKEEWLKTYQFLLMKAGQTEPLQANHQFTPDAIALLLVFIV
                     EELFKEEEITILEMGSGMGILGAIFLTSLTKKVDYLGMEVDDLLIDLAASMADVIGLQ
                     AGFVQGDAVRPQMLKESDVVISDLPVGYYPDDAVASRHQVASSQEHTYAHHLLMEQGL
                     KYLKSDGYAIFLAPSDLLTSPQSDLLKEWLKEEASLVAMISLPENLFANAKQSKTIFI
                     LQKKNEIAVEPFVYPLASLQDASVLMKFKENFQKWTQGTEI"
     gene            21696..22886
                     /locus_tag="VU534_000777"
     CDS             21696..22886
                     /locus_tag="VU534_000777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HEU1513390.1"
                     /translation="MTKTIAINAGSSSLKWQLYLMPEEKVLAKGLIERIGLKDSISTV
                     KFDGRSEQQILDIENHIQAVKILLDDLIRFDIIKAYDEITGVGHRVVAGGEYFKESTV
                     VEGDVLEKVEELSLLAPLHNPANAAGVRAFKELLPDITSVVVFDTSFHTSMPEKAYRY
                     PLPTKYYTENKVRKYGAHGTSHQFVAGEAAKLLGRPLEDLKLITCHIGNGGSITAVKA
                     GKSVDTSMGFTPLGGIMMGTRTGDIDPAIIPYLMQYTEDFNTPEDISRVLNRESGLLG
                     VSANSSDMRDIEAAVAEGNHEASLAYEMYVDRIQKHIGQYLAVLNGADAIVFTAGVGE
                     NAESFRRDVISGISWFGCDVDDEKNVFGVTGDISTEAAKIRVLVIPTDEELVIARDVE
                     RLKK"
     gene            23035..23406
                     /gene="rnpA"
                     /locus_tag="VU534_000778"
     CDS             23035..23406
                     /gene="rnpA"
                     /locus_tag="VU534_000778"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000739244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HEU1513391.1"
                     /translation="MKKNFRVKREKDFKAIFKEGTSFANRKFVVYQLENQKNRFRVGL
                     SVSKKLGNAVTRNQIKRRIRHIIQNAKGSLVEDVDFVVIARKGVETLGYAEMEKNLLH
                     VLKLSKIYREGNGSEKETKVD"
     gene            23381..24205
                     /locus_tag="VU534_000779"
     CDS             23381..24205
                     /locus_tag="VU534_000779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HEU1513392.1"
                     /translation="MKKKLKLTSLLGLSLLIMTACATNGVTSDITAESADFWSKLVYF
                     FAEIIRFLSFDISIGMGIILFTVLIRTVLLPVFQVQMVASRKMQEAQPRIKALREQYP
                     GRDMESRTKLEQEMRKVFKEMGVRQSDSLWPILIQMPVILALFQALSRVDFLKTGHFL
                     WINLGSVDTTLVLPILAAVFTFLSTWLSNKALSERNGATTAMMYGIPVLIFIFAVYAP
                     GGVALYWTVSNAYQVLQTYFLNNPFKIIAEREAVVQAQKDLENRKRKAKKKAQKTK"
     gene            24224..25210
                     /locus_tag="VU534_000780"
     CDS             24224..25210
                     /locus_tag="VU534_000780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein jag"
                     /protein_id="HEU1513393.1"
                     /translation="MVVFTGSTVEEAIQKGLKELDIPRMKAHIKVISREKKGFLGLFG
                     KKPAQVDIEAISETTVVKANQQVVKGVPKKINDLNEPVKTVSEETVDLGHVVDAIKKI
                     EEEGQGISDEVKAEILKHERHASTILEETGHIEILNELQIEEAMREEAGADDLETEQD
                     QAESQELEDLGLKVETNFDIEQVATEVMAYVQTIIDDMDVEATLSNDYNRRSINLQID
                     TNEPGRIIGYHGKVLKALQLLAQNYLYNRYSRTFYVTINVNDYVEHRAEVLQTYAQKL
                     ATRVLEEGRSHKTDPMSNSERKIIHRIISRMDGVTSYSEGDEPNRYVVVDTE"
     gene            25261..25884
                     /locus_tag="VU534_000781"
     CDS             25261..25884
                     /locus_tag="VU534_000781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000932659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P"
                     /protein_id="HEU1513394.1"
                     /translation="MLNKIRDYLDFAGLQYRNPDKAGAEREKMLAFRHKGQEARKVFT
                     ELAKAFQASHPEWQLQQTSQWMNQAQRLRPHFWVYLQRDGQVTEPMMALRLYGTSTDF
                     GISLEVSFIERKKDEQTLGKQAKVLDIPTVKGIYYLTYSNGQSQRWEANEEKRRTLRE
                     KVRSQEVRKVLVKVDVPMTENSSEEEIVEGLLKSYSKILPYYLATRK"
     gene            26015..27472
                     /locus_tag="VU534_000782"
     CDS             26015..27472
                     /locus_tag="VU534_000782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HEU1513395.1"
                     /translation="MEVVSSVLNWFSSNILQNPAFFVGLLVLIGYALLKKPAHDVFSG
                     FVKATVGYMLLNVGAGGLVTTFRPILAALNYKFQIGAAVIDPYFGLAAANNKIVAEFP
                     DFVGTATTALLIGFGINILLVALRKITKVRTLFITGHIMVQQAATVSLMVLFLVPQLR
                     NAYGTAAIGIICGLYWAVSSNMTVEATQRLTGGGGFAIGHQQQFAIWFVDKVAGRFGK
                     KEESLDNLKLPKFLSIFHDTVVASATLMLVFFGAILLILGPDIMSNKEVITSGTLFNP
                     AKQDFFMYIIQTAFTFSVYLFVLMQGVRMFVSELTNAFQGISNKLLPGSFPAVDVAAS
                     YGFGSPNAVLSGFTFGLIGQLITIVLLIVFKNPILIITGFVPVFFDNAAIAVYADKRG
                     GWKAAVILSFISGVLQVALGALCVALLDLASYGGYHGNIDFEFPWLGFGYIFKYLGIV
                     GYVLVCLFLLVIPQLQFAKAKDKEKYYNGEVQEEA"
     gene            27495..27776
                     /locus_tag="VU534_000783"
     CDS             27495..27776
                     /locus_tag="VU534_000783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEU1513396.1"
                     /translation="MVKVLAACGNGMGSSMVIKMKVENALRKLNQTDFTVNSCSVGEA
                     KGLAVGYDIVIASLHLIQELEGRTNGKLIGLDNLMDDKEITEKLSQALQ"
     gene            27853..28338
                     /locus_tag="VU534_000784"
     CDS             27853..28338
                     /locus_tag="VU534_000784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEU1513397.1"
                     /translation="MNLKQALIDNDSIRLGLEANNWKEAVKVAVDPLIESGAILPEYY
                     DAIIESTEEYGPYYILMPGMAMPHARPEAGVQSDAFSLITLQNPVVFSDGKEVSVLLA
                     LAATSSKIHTSVAIPQIIALFELEDSIARLQACQTKEDVLAMIEESKDSPYLEGLDLE
                     S"
     gene            28355..29020
                     /locus_tag="VU534_000785"
     CDS             28355..29020
                     /locus_tag="VU534_000785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HEU1513398.1"
                     /translation="MTKRIPNLQVALDHSDLQGAIKAAVSVGQEVDIIEAGTVCLLQV
                     GSELAEVLRSLFPDKIIVADTKCADAGGTVAKNNAVRGADWMTCICCATIPTMEAALK
                     AIKTERGERGEIQIELYGDWTFEQAQLWLDAGISQAIYHQSRDALLAGETWGEKDLNK
                     VKKLIDMGFRVSVTGGLDVDTLKLFEGIDVFTFIAGRGITEAVDPAGAARAFKDEIKR
                     IWG"
     gene            29024..29887
                     /locus_tag="VU534_000786"
     CDS             29024..29887
                     /locus_tag="VU534_000786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000252119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HEU1513399.1"
                     /translation="MVRPIGIYEKATPTHCTWLERLNFAKELGFDFVEMSIDERDERL
                     ARLDWSKEERLEVVKAIYETGVRIPSICFSGHRRYPLGSKDPVLEEKSLELMKKCIEL
                     AQDLGVRTIQLAGYDVYYEEKSPQTRQRFIKNLRKACDWAEEAQVVLAIEIMDDPFIS
                     SIEKYLAIEKEIDSPFLFVYPDIGNVSAWHNDIYSEFYLGHHAIAALHLKDTYAVTES
                     SKGQFRDVPFGQGCVKWEEAFDILKETNYNGPFLIEMWSENCETVEETRAAIQEAQAF
                     LYPLIKKAGLM"
     gene            29889..30593
                     /locus_tag="VU534_000787"
     CDS             29889..30593
                     /locus_tag="VU534_000787"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HEU1513400.1"
                     /translation="MNQVINAMRKRVCDANQSLPKHGLVKFTWGNVSEVNRELGVIVI
                     KPSGVDYDELTPENMVVTDLDGKILEGDLRPSSDLPTHVQLYKTWSEIGSVVHTHSTE
                     AVGWAQAGRDIPFYGTTHADYFYGSIPCARSLTKDEVEVAYEKDTGLVIVEEFEHRGL
                     NPVEVPGIVVRNHGPFTWGKNPENAVYHSVVLEEVSKMNRFTEQINPRVGPAPQYILE
                     KHYQRKHGPNAYYGQK"
     gene            30772..32445
                     /locus_tag="VU534_000788"
     CDS             30772..32445
                     /locus_tag="VU534_000788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HEU1513401.1"
                     /translation="MVLDKASCDLLQYLMDQETSKTIMAISKDLKESRRKIYYHIDKI
                     NAALGDEALHIISIPRIGIHLTEEQRDACCKLLSEVDSYDYIMSAHERMMIMLLWIGI
                     SKERITIEKLIELTEVSRNTVLNDLNSIRYQLTLEQYQVILQVSKSQGYNLHAHPLNK
                     IQYLQSLLYHIFMEENATFVSILEDKMKERLDDECLLSVEMNQFFKEQVPLVEQDLGK
                     KINHHEITFMLQVLPYLLLSCHNVEQYQERHQDIEKEFSLIRKRIEYQVSKKLGERLF
                     QKFEISLSGLEVSLVAVLLLSYRKDLDIHAESDDFRQLKLALEEFIWYFESQIRMEIE
                     NKDDLLRNLMIHCKALLFRKTYGIFSKNPLTKQIRSKYGELFLVTRKSAEILEGAWFI
                     RLTDDDIAYLTIHIGGFLKYTPSSQKNMKKVYLVCDEGVAVSRLLLKQCKLYFPNEQI
                     DTVFTTEQFKSVEDIAQVDVVITTNDDLDSRFPILRVNPILEAEDILKMLDYLKHNIF
                     RNKSKSFSENLSSLISSYIVDSKLASKFQEEVQTLINQEIVVQAFLEDI"
     gene            32557..33648
                     /gene="ulaG"
                     /locus_tag="VU534_000789"
     CDS             32557..33648
                     /gene="ulaG"
                     /locus_tag="VU534_000789"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HEU1513402.1"
                     /translation="MPNVKEITRESWILATFPEWGTWLNEEIEEEVVPEGNFAMWWLG
                     NCGTWIKTPAGANVVMDLWSNRGKSTKKVKDMVRGHQMANMAGVRKLQPNLRVQPMVI
                     DPFAINELDYYLVSHFHSDHIDPYTAAAILNNPKLEHVKFIGPYHCGRIWEGWGVPKE
                     RIIVVKPGDTIELKDMKIHAVESFDRTCLVTLPVNGADETGGELAGLAVTDEEMAQKA
                     VNYIFETPGGTIYHGADSHFSNYFAKHGKDFKIDVALNNYGENPVGIQDKMTSIDLLR
                     MAENLRTKVIIPVHYDIWSNFMASTNEILELWKMRKDRLQYDFHPFIWEVGGKYTYPQ
                     DQHLVEYHHPRGFDDCFEQDSNIQFKALL"
     gene            33762..35738
                     /gene="tkt"
                     /locus_tag="VU534_000790"
     CDS             33762..35738
                     /gene="tkt"
                     /locus_tag="VU534_000790"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004185329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HEU1513403.1"
                     /translation="MSNLSVNAIRFLGIDAINKANSGHPGVVMGAAPMAYSLFTKQLH
                     INPAQPNWINRDRFILSAGHGSMLLYALLHLSGFEDVSMDEIKSFRQWGSKTPGHPEF
                     GHTAGIDATTGPLGQGISTATGFAQAERFLAAKYNREGYNIFDHYTYVICGDGDLMEG
                     VSSEAASYAGLQKLDKLVVLYDSNDINLDGETKDSFTESVRDRYNAYGWHTALVENGT
                     DLEAIHAAIETAKASGKPSLIEVKTVIGYGSPNKQGTNAVHGAPLGADETASTRQALG
                     WDYEPFEIPEQVYADFKEHVADRGASAYQAWTKLVADYKEAHPELAAEVEAIIDGRDP
                     VEVTPADFPALENGFSQATRNSSQDALNVVAAKLPTFLGGSADLAHSNMTYIKTDGLQ
                     DDANRLNRNIQFGVREFAMGTILNGMALHGGLRVYGGTFFVFSDYVKAAVRLSALQGL
                     PVTYVFTHDSIAVGEDGPTHEPVEHLAGLRAMPNLNVFRPADARETQAAWYLAVTSEK
                     TPTALVLTRQNLTVEDGTDFDKVAKGAYVVYENAADFDTILIATGSEVNLAVSAAKEL
                     ASQGEKIRVVSMPSTDVFDKQDAAYKEEILPNAVRRRVAVEMGASQNWYKYVGLDGAV
                     LGIDTFGASAPAPKVLAEYGFTVENLVKVVRNLK"
     gene            35855..36154
                     /gene="yajC"
                     /locus_tag="VU534_000791"
     CDS             35855..36154
                     /gene="yajC"
                     /locus_tag="VU534_000791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HEU1513404.1"
                     /translation="MNPNITFLIMLVGMMALMFFMQRSQKKQAQKRMESLNKLQKGYE
                     VITIGGLYGTVDEVDTEKGTIVLDVDGVYLTFELAAIKTVLPLKETASLEGAIEK"
     gene            36200..36628
                     /locus_tag="VU534_000792"
     CDS             36200..36628
                     /locus_tag="VU534_000792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000737444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight phosphotyrosine protein
                     phosphatase"
                     /protein_id="HEU1513405.1"
                     /translation="MKKLVFVCLGNICRSPMAEFVMKSMTDNYEIQSRATSSWEHGNP
                     IHKGTQGIFQEYEIPYDKNKTSLQISKEDFEAFDYIIGMDASNISDLRQMCPVDCQDK
                     IYSFSSESVPDPWYTGDFEETYRRVQEGCQAWLERLEKES"
     gene            36630..37040
                     /locus_tag="VU534_000793"
     CDS             36630..37040
                     /locus_tag="VU534_000793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000427064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1513406.1"
                     /translation="MENLTNFYEKYRVYLTRPRLELLAVVTIVFCAVLVFFLNIPGKG
                     VLKLDNGTIVYDGSLVRGKMNGQGTITFQNGDQYTGGFNNGAFNGKGTFQSKEGWTYE
                     GDFVNGQAEGKGKLTTEQEVVYEGTFKQGVFQQK"
     gene            37340..39991
                     /gene="adhE"
                     /locus_tag="VU534_000794"
                     /gene_synonym="adhC"
     CDS             37340..39991
                     /gene="adhE"
                     /locus_tag="VU534_000794"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000763984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HEU1513407.1"
                     /translation="MADKKTVTPEEKKLVAEKHVDELVQKALVALEEMRKLDQEQVDY
                     IVAKASVAALDAHGELALHAFEETGRGVFEDKATKNLFACEHVVNNMRHTKTVGVIEE
                     DDVTGLTLIAEPVGVVCGITPTTNPTSTAIFKSLISLKTRNPIVFAFHPSAQESSAHA
                     ARIVRDAAIAAGAPENCVQWITQPSMEATSALMNHEGVATILATGGNAMVKAAYSCGK
                     PALGVGAGNVPAYVEKSANIRQAAHDIVMSKSFDNGMVCASEQAVIIDKEIYDEFVAE
                     FKSYHTYFVNKKEKALLEEFCFGVKANSKNCAGAKLNADIVGKPATWIAEQAGFTVPE
                     GTNILAAECKEVGENEPLTREKLSPVIAVLKSESREDGITKARQMVEFNGLGHSAAIH
                     TADEELTKEFGKAVKAIRVICNSPSTFGGIGDVYNAFLPSLTLGCGSYGRNSVGDNVS
                     AINLLNIKKVGRRRNNMQWMKLPSKTYFERDSIQYLQKCRDVERVMIVTDHAMVELGF
                     LDRIIEQLDLRRNKVVYQIFADVEPDPDITTVNRGTEIMRAFKPDTIIALGGGSPMDA
                     AKVMWLFYEQPEVDFRDLVQKFMDIRKRAFKFPLLGKKTKFIAIPTTSGTGSEVTPFA
                     VISDKANNRKYPIADYSLTPTVAIVDPALVLTVPGFVAADTGMDVLTHATEAYVSQMA
                     SDYTDGLALQAIKLVFENLESSVKNADFHSREKMHNASTIAGMAFANAFLGISHSMAH
                     KIGAQFHTIHGRTNAILLPYVIRYNGTRPAKTATWPKYNYYRADEKYQDIARMLGLPA
                     STPEEGVESYAKAVYELGERIGIQMNFRDQGIDEKEWKEHSRKLAFLAYEDQCSPANP
                     RLPMVDHMQEIIEDAYYGYKERPGRRK"
     gene            complement(40977..41285)
                     /locus_tag="VU534_000795"
     CDS             complement(40977..41285)
                     /locus_tag="VU534_000795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000134125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEU1513408.1"
                     /translation="MTEEMEYICFQLIANSGAAKSSFIEAIQLAKAGNLKEAKIKVEE
                     AEDSLVEAHKIHSNLIQKEATGEKIGFSLLFMHAEDQMASTEIIQLLSKEFIDLYQNK
                     "
     gene            complement(41282..41590)
                     /locus_tag="VU534_000796"
     CDS             complement(41282..41590)
                     /locus_tag="VU534_000796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEU1513409.1"
                     /translation="MKQILLVCNAGMSTSMLVKKMQQSATERGIEISIQAKSMTEAKK
                     NIHEADVILIGPQIRYELLAVKEIAGNIPVDTIDMRDYGMMNGAKVLEQALAWIGEIR
                     "
     gene            complement(41595..42890)
                     /locus_tag="VU534_000797"
     CDS             complement(41595..42890)
                     /locus_tag="VU534_000797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000798148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEU1513410.1"
                     /translation="MKNSKFIDQFATFAGKLGNQIHLKTLRDAFVTVMPLYILAGLIV
                     LLNNTVFKWIFQGDTLTRFQYWGITIANGTLSISGMIIAVMVGYFLAKNRDFENPLAA
                     SMLSLVSLIVMMPNTVSVVPDGAKDAVNISGVLSFNNTGTGAMFAGVIVAIIATELFI
                     ELSNVKALQMNLGENIPPAVSRSFSVLLPVMTVISLFGVVSALLFNITGMNLISIITI
                     FIQEPIRHIGTSLIGVIIIYSLGNMLWLFGIHQAVIYSAILEPLLLINITENITAANN
                     GQAIPHIINLSQIQTFALMGGSGSTLCLLIATFLVSRNAVSKNVAKLSFGPGIFNINE
                     PVLFGYPIVYNISLAIPFITVPVLGILISYLATVTEFMSPAFIQVPWTTPVFLNAWLA
                     TAGDVRAVLVQFIIFALGVLLYIPFIKVNDKVVEQEMEG"
     gene            complement(42908..44317)
                     /locus_tag="VU534_000798"
     CDS             complement(42908..44317)
                     /locus_tag="VU534_000798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HEU1513411.1"
                     /translation="MKKKLVFPNLFWWGAASSGPQTEGQYGKVHENVMDYWFKTHPED
                     FFDNVGPLVASNFFHTYTEDFHLMKEIGVNSFRTSIQWSRLIKNLETGEPDPKGIAFY
                     NAIIEEAKKNQMDLVMNLHHFDLPVELLQKYGGWESKHVVELFVKFAKTAFTCFGDKV
                     HYWTTFNEPMVIPEAGYLYAFHYPNLKGKGKEAVQVIYNLNLASAKVIQLYRSLELDG
                     KIGIILNLTPAYPRSNSPEDLEASRFTDDFFNKVFLNPAVKGTFPERLVKQLERDGVL
                     WSHTEKELQLMKSNTVDFLGVNYYHPKRVQAQANPEEYQTPWMPDQYFKEYEWLERRM
                     NPYRGWEIFPKAIYDIAMIVKEEYGNIPWFISENGMGVENEARFIDENGVIDDVYRIE
                     FYEEHLRWLHKAIEEGSHCFGYHAWTAFDCWSWNNAYKNRYGFISVDLETQKRTIKSS
                     GRWYRKVSDNNGFEVEIEE"
     gene            44475..45203
                     /locus_tag="VU534_000799"
     CDS             44475..45203
                     /locus_tag="VU534_000799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEU1513412.1"
                     /translation="MSTKYLFIYNEIREKILCNKYTMNEQLPDEMTLAKQFACSRMTI
                     KKALDLLVSEGLIFRKRGQGTFVLSRGSSKRKLIVPERDIRGLTKISEDAHSTIDSRI
                     IHFKLEFANEFLAEKLQVALQSPVYNIYRLRIIDGKPYVLEQTYMSTDVIPGITEDIL
                     QKSIYNYIEGKLGLHIASATKILRASSSSENEQHYLQLLPTEPVFEVEQVAYLDNGTP
                     FEYSISRHRYDLFEFNSFALRHSS"
     gene            45662..45856
                     /locus_tag="VU534_000800"
     CDS             45662..45856
                     /locus_tag="VU534_000800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEU1513413.1"
                     /translation="MKGKEYENRTVSFAISSKGEKMKVENISYRVDHRKLFDNISFDT
                     SSSDVTLITGKNGTGKSTLL"
     gene            complement(46222..47532)
                     /locus_tag="VU534_000801"
     CDS             complement(46222..47532)
                     /locus_tag="VU534_000801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SLC13 family permease"
                     /protein_id="HEU1513414.1"
                     /translation="MIHLIMISAIALAIGIGYRTKINIGLLAIAFSYLIATTLMGLSP
                     KELLHFWPTSLFFTIFSVSLFYNVATTNGTLDVLAQHILYRTRTHPNALYMILYLMAT
                     LLSALGAGFFTTMAVCCPLAITLCQKADKHPLIGAQAVNWGASGGANLITSSSGIVFQ
                     GLFKQMGWEEQAFSLGNHIFIVSIIYPLIVLLLLSCYSHYSKGRTNSSLTIDQPPLLS
                     KVQRQTTLLMISSMVLVWLFPLLHLIFPNIAWIATYQKTFDIGFVSILMVCLALRLKL
                     GKQEAILAKVPWATIIMLCGMSLLMSLAVKSGLVTLIGHLMTTTIPHFWLPLFFCVIA
                     GVMSLFSSTLSVVAPALFPIIAIISAQNPQIDIHLLTTATVIGALSTNISPFSSAGSL
                     IQLSLPNIEERGLAFKKQIILGVPISLSLGLLTTWILILLASLS"
     gene            47769..48641
                     /locus_tag="VU534_000802"
     CDS             47769..48641
                     /locus_tag="VU534_000802"
                     /EC_number="2.4.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxylating nicotinate-nucleotide
                     diphosphorylase"
                     /protein_id="HEU1513415.1"
                     /translation="MSIISTDLTPFQIDDTLKAALREDVHSEDYSTNAIFDHHGQAKV
                     SLFAKEAGVLAGLTVFQRVFTLFDAEVTFQNPHQFKDGDRLTSGDLVLEIIGSVRSLL
                     TCERVALNFLQHLSGIASMTAAYVEALGDDCIKVFDTRKTTPNLRLFEKYAVRVGGGY
                     NHRFNLSDAILLKDNHIAAVGSVQKAIAQARAYAPFVKMVEVEVESLAAAEEAAAAGA
                     DIIMLDNMSLEQIEQAITLIAGRSRIECSGNIDMTTISRFRGLAIDYVSSGSLTHSAK
                     SLDFSMKGLTYLDV"
BASE COUNT        14889 a         8711 c        10681 g        14530 t
ORIGIN      
        1 tttagcgggt gtagtttagt ggtaaaacta cagccttcca agctgttgtc gcgagttcga
       61 ttctcgtcac ccgctttgaa ctttgttctt tgtaccaagt ttttgacttg ggcgcgtagc
      121 tcaggtggtt agagcgcacg cctgataagc gtgaggtcgg tggttcgagt ccactcgtgc
      181 ccatagtgtt tagtccatta ctaggggatt ggaatattat ctgttcacta agaggacacg
      241 ggcttgttcc cgtataaact attttggagg attacccaag tccggctgaa gggaacggtc
      301 ttgaaaaccg tcaggcgtgt aaaagcgtgc gtgggttcga atcccacatc ctccttttat
      361 attaacgcgg gatggagcag ctcggtagct cgtcgggctc ataacccgaa ggtcgtaggt
      421 tcaaatcctg ctcccgcaat aaggctcggt agctcagttg gtagagcaat ggattgaagc
      481 tccatgtgtc ggcggttcga ttccgtctcg cgccatttat atattttgga agggtagcga
      541 agaggctaaa cgcggcggac tgtaaatccg ctccttcggg ttcgggggtt cgaatccctc
      601 cccttccatt ttacgggcat agtttaaagg tagaactaag gtctccaaaa ccttcagtgt
      661 gggttcaatt cctactgccc gtgttaatag aattatggcg ggtgtggtga agtggttaac
      721 acaccagatt gtggctctgg catgcgtggg ttcgatcccc atcactcgcc tattttatat
      781 tggggtatag ccaagcggta aggcaaggga ctttgactcc ctcatgcgtt ggttcgaatc
      841 cagctacccc agttactatt tgccggcgtg gcggaattgg cagacgcgct ggactcaaaa
      901 tccagtgtcc gcaaggacgt gccggttcga ccccggccgc cggtatagta tagtgttagg
      961 aacgttgtta ttcttcgttc cttttttata ttatttttgg tataattata gttattcaaa
     1021 ttttatttag attaagaaag tgtaggggag tatgtcttgt tctatcgatt tattaaaaca
     1081 tcggtatttg aaaaatatta aagaaaatcc tgaattgttt gtcggaattg agttggagta
     1141 tcctgttgca agtttagaag gggatgctac agatgttgaa gttatgaagg atctatttca
     1201 ttatttagtt tctactttgg atctcaccgt agcaaaggta gatgattttg gcaatctgat
     1261 ccagttagta gatccgataa gtcaggatgc tattttattt gaagtttcct atacaacgat
     1321 tgagtttgca tttggtaagg ctgaaacgat tcaagaggtc gaaaatcgtt tcaataatta
     1381 tatgaatgta attcagagaa agttagctga atcaaatcat gctattgttg gctgtggtat
     1441 ccatcccaac tgggataaaa atgagaattg tccagtggct tatccacgct atcagatgtt
     1501 gatggattat ttgaatttga gtagaaatat tattaaatca gatttacatc atttccctga
     1561 atatggtact tttatctgtg ggagccaggt tcagctggat atttcaaaaa ccaactactt
     1621 acgggtgatt aatgctttta ctcaaattga agcggctaag gcttatttat ttgcaaactc
     1681 tgaattttcg ggtgcggatt gggatacgaa aatttcaagg gatattttct gggaagaatc
     1741 tatgcatggt atctatccag agaatgttgg ggtcaatgct agactcctta atgatgaaac
     1801 tgattttttt gactatctaa atcattctgc gatttttact gcggaacgtg atgggcagac
     1861 ctattatttt tatcctattc aggctgggga ctatttggct acgtccgaaa tccaagcatt
     1921 tgctctgaat ggggatgagg ttattattta cccccaagag aaggattttg aaactcatcg
     1981 tagttaccag taccaagatt taacgactcg aggaacagtt gagtttcgta gtgtgtgtac
     2041 acagccactt gataggactt ttgcttctgc agcttttcac ttgggattat tggttaattt
     2101 agacaagtta gaagcttact tagaaacagc acctttcttt aaagtatttg gttatgatta
     2161 caagtcttta aggagacaat tttctaagaa aaatcttaca gatgaggaag aaactacgat
     2221 tattgaattt tccaaagact tactcctact agctgaggag ggactagtgg tgagaaataa
     2281 ggaagaaatg acctatttac agcctttgag agaagaattg agcctataat ttctcttata
     2341 aagggagaat tttctgaaaa atcatgatat aatggacgag actatagata aaggatagag
     2401 agtaatgaca ttagtttatc aatcaacgcg tgatgccaac aatacagtaa ctgccagcca
     2461 agcaattttg caaggtttgg cgacggacgg cggtttgttt acaccggata cttatccaaa
     2521 ggtagatttg aactttgaca aattgaaaga tgcttcttac caggaagttg ctaagctagt
     2581 tttgtcagca tttttagatg actttacagt tgaggagttg gactactgta tcaacaatgc
     2641 ctacgatagc aaatttgata ctccagctat tgcaccatta gtgaaattag atgggcaata
     2701 caatttggaa cttttccatg gttcaacgat tgcctttaag gatatggcct tgtctatttt
     2761 gccatacttt atgacgactg ctgctaagaa acatggtttg gagaacaaga ttgttatctt
     2821 gacagcgaca tctggtgaca cggggaaagc tgctatggcg gggtttgcga atgtgcctgg
     2881 tactgagatt atcgtctttt atccaaagga tggtgtcagc aagattcaag agttacaaat
     2941 gaccactcag actggcgaca atactcatgt tattgctatt gatggtaact ttgacgatgc
     3001 gcaaacaaat gtgaagcaca tgtttaacga cgtggctctt cgtgaaaaat tgactaccaa
     3061 caagttgcaa ttttcatcag ctaactctat gaacattggt cgtctggtgc cacaaattgt
     3121 ttattatgtt tatgcttacg ctcaattggt taagactggt gaaattgtag ctggtgaaaa
     3181 ggttaacttc acagtaccaa caggaaactt tggaaatatc ttggctgcct tttatgccaa
     3241 acaaattggt ttgccagttg gtaaattaat ctgtgcttca aatgacaaca atgttttgac
     3301 agacttcttt aaaacacgtg tctatgacaa aaaacgtgag tttaaggtaa caaccagccc
     3361 atctatggat atcttggtat cttcaaactt ggagcgcttg attttccatc ttttgggaaa
     3421 taatgctgaa aagacaactg aacttatgaa tgccttgaac acgcaaggac aatataagtt
     3481 gacagacttt gatgcagaga ttttggacct ctttgcagct gaatatgcga ctgaggaaga
     3541 aacggcagca gagatcaagc gtgtttgtga gttagattct tatatcgagg accctcatac
     3601 agctgttgct tcagcagttt ataaaaaata ccaatcggcc actggagatg taactaagac
     3661 agtgattgct tcaacagcta gtccatacaa gttcccagta gttgcagtag aagctgtaac
     3721 tggaaaagca ggtttaacag actttgaagc cttggctcaa ttacatgaaa tctcaggcgt
     3781 tgcagtgcca ccagcagttg atgggcttga aatagctcca attcgtcaca agacaacagt
     3841 ggcagctgct gacatgcaag cagcggttga ggcttattta ggactttaag acagagggag
     3901 caaactcggt tgggaaacca actgagtttc ttttcatcag gaggagagat tgtttaagaa
     3961 aaataaagac attcttaata ttgcattgcc agctatgggt gaaaactttt tgcagatgct
     4021 aatgggaatg gtggacagtt atttggttgc tcatttagga ttgatagcta tttcaggggt
     4081 ttcagtagct ggtaatatta tcaccattta tcaggcgatt ttcatcgctc tgggagctgc
     4141 tatttccagt gttatttcaa aaagcatagg gcagaaagac cagtcgaagt tggcctatca
     4201 tgtgactgag gcgttgaaga ttaccttact attaagtttc cttttaggat ttttgtcaat
     4261 cttcgctggg aaagagatga taggactttt ggggacggag agggatgtag ctgagagtgg
     4321 tggactgtat ctatctttgg taggcggatc gattgttctc ttaggtttaa tgactagtct
     4381 aggagccttg attcgtgcaa cgcataatcc acgtctgcct ctctatgtta gttttttatc
     4441 caatgccttg aatattcttt tttcaagtct agctattttt gttctggata tggggatagc
     4501 tggtgttgct tgggggacaa ttgtgtctcg tttggttggt cttgtgattt tgtggtcaca
     4561 attaaaactg ccttatggga agccaacttt tggtttagat aaggaactgt tgaccttggc
     4621 tttaccagca gctggagagc gacttatgat gagggctgga gatgtagtga tcattgcctt
     4681 ggtcgtttct tttgggacgg aggcagttgc tgggaatgca atcggagaag tcttgaccca
     4741 gtttaactat atgcctgcct ttggcgtcgc tacggcaacg gtcatgctgt tggcccgagc
     4801 agttggagag gatgattgga aaagagttgc tagtttgagt aaacaaacct tttggctttc
     4861 tctgttcctc atgttgcccc tgtcctttag tatatatgtc ttgggtgtac cattaactca
     4921 tctctatacg actgattctc tagcggtgga ggctagtgtt ctagtgacac tgttttcact
     4981 acttgggacc cctatgacga caggaacagt catctatacg gcagtctggc agggattagg
     5041 aaatgcacgc ctcccttttt atgcgacaag tataggaatg tggtgtatcc gcattgggac
     5101 aggatatctg atggggattg tgcttggttg gggcttgcct ggtatttggg cagggtctct
     5161 cttggataat ggttttcgct ggttatttct acgctatcgt taccagcgct atatgagctt
     5221 gaaaggatag gaaatgcaaa aaacagcttt tatttgggat ttagacggga ctttattgga
     5281 ctcttacgaa gcgattttat cagggattga ggagactttt gctcagtttt ctattcctta
     5341 tgataaggag aaggtgagag agtttatctt caagtattcg gtgcaagatt tgcttgtgcg
     5401 ggtggcagaa gatagaaatc tggatgttga ggtgctaaat caggtgcgtg cccagagtct
     5461 ggctgagaag aatgctcagg tagttttgat gccaggtgcg cgtgaggtgc tagcttgggc
     5521 agacgaatca ggaattcagc agtttatata tactcataag gggaacaacg cttttaccat
     5581 tctcaaggac ttgggggtgg aatcctattt tacagagatt ttaaccagtc agagtggctt
     5641 tgtgcggaag ccaagtccag aagcggctac ctatctgcta gataagtatc agttgaattc
     5701 tgataatact tattatatag gggatcggac tctggatgtg gaatttgccc agaatagtgg
     5761 gattcaaagc atcaactttt tagagtctac ttatgaaggg aatcacagga ttcaagcgtt
     5821 agcagatatt tcccgtattt ttgagactaa gtgataaaaa gattgtgtca gttttgtgac
     5881 agagacctaa caaactattt caagtaacct agtttgttac aaggaataga cagttctgtt
     5941 aaataggccc gagagggctt tttttctaca ttttttgtgt tatgatagac aggtactcat
     6001 ttgaaaggaa tttgaaagaa tgaagaaaag aatgttatta gcgtcaacag tagccttgtc
     6061 atttgcccca gtattggcaa ctcaagcaga agaagttctt tggactgcac gtagtgttga
     6121 gcaaatccaa aacgatttga ctaaaacgga caacaaaaca agttataccg tacagtatgg
     6181 tgatactttg agcaccattg cagaagcctt gggtgtagat gtcacagtgc ttgcgaatct
     6241 gaacaaaatc actaatatgg acttgatttt cccagaaact gttttgacaa cgactgtcaa
     6301 tgaagcagaa gaagtaacag aagttgaaat ccaaacacct caagcagact ctagtgaaga
     6361 agtgacaact gcgacagcag atttgaccac taatcaagtg accgttgatg atcaaactgt
     6421 tcaggttgca gacctttctc aaccaattgc agaagttaca aagacagtga ttgcttctga
     6481 agaagtggca ccatctacgg gcacttctgt cccagaggag caaacgaccg aaacaactcg
     6541 cccagttgaa gaagcaactc ctcaggaaac gactccagct gagaagcagg aaacacaagc
     6601 aagccctcaa gctgcatcag cagtggaagt aactacaaca agttcagaag caaaagaagt
     6661 agcatcatca aatggagcta cagcagcagt ttctacttat caaccagaag agacgaaaat
     6721 aatttcaaca acttacgagg ctccagctgc gcccgattat gctggacttg cagtagcaaa
     6781 atctgaaaat gcaggtcttc aaccacaaac agctgccttt aaagaagaaa ttgctaactt
     6841 gtttggcatt acatccttta gtggttatcg tccaggagac agtggagatc acggaaaagg
     6901 tttggctatc gactttatgg taccagaacg ttcagaatta ggggataaga ttgcggaata
     6961 tgctattcaa aatatggcca gccgtggcat tagttacatc atctggaaac aacgtttcta
     7021 tgctccattc gatagcaaat atgggccagc taacacttgg aacccaatgc cagaccgtgg
     7081 tagtgtgaca gaaaatcact atgatcacgt tcacgtttca atgaatggat aaacccgact
     7141 tgataacatc attttgacga atgagatcta gctttcgtga tggaaagcga ttctcgttcg
     7201 ttttttcttt gtcatactct tcgaaaatct cttcaaacca cgtcagtttt atctgaaact
     7261 tcaaagctgt gctttgagca acctgcgact agcttcctag tttgcttttt gattttcatt
     7321 gagtatcaat ttgaatggaa aatggaaagt tatcatcttg taatgagtta agcaacattc
     7381 ttgcaatcta ttttacttta tatcacaatt aattagtcaa atattgataa atcaataaaa
     7441 agagagggga agaaatgcta gagattcaag atttactgta tcaactccgc ttgtctgagc
     7501 aagcgagtac gcaattgttt gaaaaaaggc ttgggattag tttgacacgg tatcagattt
     7561 tactgttttt gctggagcat tctccttgta accaaatggc ggttcaggag cgtttgaaaa
     7621 ttgatcaggc tgctttgaca cggcatttca aaattttgga aacggaaggt ttggtggagc
     7681 gtcatcgtaa tcctgaaaat cagcgggaag tgttggtaga ggctgcgaag tatgccaagg
     7741 agcagttagt ggtgaatccc cctctgcaac atatcagggt taaggaagag atagaaagta
     7801 tcttaacaga gtttgagaga acagaactca gccgtttatt aaataaattg gttttgggta
     7861 ttgaaaatat agaaatttaa ggagaaatag atgtcaatta ttttaacaac gatcgttgct
     7921 ttggagcatt tttacatttt ttatttggaa agtattgcca cgcaatcaga tgcgactagt
     7981 cgtgtattta atatggaaaa ggaagaattg gctcatccgt cagtaagttc attgttcaaa
     8041 aatcaaggaa tttataaggc tctgctagga gtctttctct tgtatgtcat ttatttctca
     8101 cagaatttag aaattgtgac tatttttgtc ttatttgtga ttggtgctgc gacttacggc
     8161 tctttaacag cggataaaaa aattattttg aaacaaggtg gatcagctat tttggccttg
     8221 attagtattt tactctttaa atacacttga aggtcgattc taatctcgct aatccttttt
     8281 aatccagaat aagggaaata tgttatactt gtttttaaga aaaaagtctc attgaattgg
     8341 ttttgaggag ttagaaatga aagtattagt gacaggtttt gagccctttg gaggggaaaa
     8401 gggcaatcca gctttggagg ccattaaagg tttaccagct gaaatccatg gtgctgaggt
     8461 ccgttggcta gaggtgccga cagtttttca caaatctgct caagtattgg aagaagagat
     8521 gaatcgttat caacctgact ttgtcctttg tattgggcaa gctggtggaa gaactagttt
     8581 gacacctgaa cgagtgacca ttaatcaaga cgatgcatgc atttctgata acgaagataa
     8641 tcaaccgatt gaccgtccca ttcgcccaga tggtgcttcg gcctacttta gtagtttgcc
     8701 gattaaagcg atggttcaag ctataaaaaa agagggctta ccggcctctg tttccaatac
     8761 ggcagggact tttgtctgca gccatttgat gtatcaggct ctctatttgg tagaaaagaa
     8821 atctccatat gttaaggcag gttttatgca tattccttat atgatggaac aggtggtgaa
     8881 cagaccgact actccagcta tgagtttagt ggatattcgg cgagggatag aagcagcaat
     8941 cggcgctata atagaacatg gagatcagga actcaagttg gtaggcggag aaactcattg
     9001 atagaaaaaa gcttgagggg aaaaaccttc aagcttttgg acgttttcgg gccaatactg
     9061 ctcggtaaaa cataatttta gtgcattgga tataaggtag gagtgaaaaa ctagcaatgc
     9121 caaaggtaat ccaattgagg aagtaccaag gaagaagctg taaatctagg acaaagtgct
     9181 ggaacttgta gcccttcata aaggaacggc tagtttttag gattcgtctt ggtgggacct
     9241 gtcctaggtc tagactataa cagagaagaa attccacctg tgaataggca taatactgtg
     9301 gaatatagag gatatttcct acaatgatca agatgagact tgcaagaaag tagagtccaa
     9361 agaccatgag gaaacgctcg gtttcaactg atgagagatc tagatttgga aactcaggat
     9421 gtagggtgac gaattttttg gctaaaaagc tactataaaa gaggaggtaa atcccaagta
     9481 aattagggat actccataaa aagagataga aacgtttgag aagtagggtc aaaaaggttt
     9541 gagaaaagcg ctcctcatca aagagagcta ggctgttttt tacagatggc tccgttttag
     9601 aatctttcat gagtgtcagt gttgcataga cggaactggt caaaagaata gtcccgataa
     9661 aggagactag tagaggaaag aggtaggttt gaagtatttg gccaagtatg ctgaaaaatg
     9721 gctgttctaa aacagtcccg tggatccgag ataagggatt aagaaaacca gataagatga
     9781 ccagcatact gggaaggata tagaggagaa agagacgggg ggtgtcagcc tgaaaatgtt
     9841 ttgactcctg acgaattgtt tttaaatcaa tttttggata gttcattctc ttattatacc
     9901 atagttctta tacatagttc gtgacagttc ctactttttt tgataaaatc atacagtgtg
     9961 tccttgggca cactgtatga actgggactg tctttcccag cttcggaggt aaaaaatgtc
    10021 agattcacca atcaaatatc gtttgattaa gaaagaaaaa cacacaggag ctcgtctggg
    10081 agaaatcatc actccccacg gtacctttcc gacacctatg tttatgccag ttgggacaca
    10141 agccactgtc aaaactcagt cacctgaaga attgaaggag atgggttcgg gaattatcct
    10201 atcaaacacc tatcatctct ggcttcgccc tggagatgaa ctcattgcac gcgctggtgg
    10261 tctccacaag ttcatgaatt gggaccagcc tatcttgaca gatagtggtg gttttcaggt
    10321 ttattcttta gcagatagcc gtaatatcac agaagaagga gtaaccttta aaaatcatct
    10381 aaatggttct aagatgttcc tatccccaga aaaagccatc tctattcaga ataatctggg
    10441 ttcagacatc atgatgtcct ttgatgaatg tcctcagttt tatcaacctt atgactacgt
    10501 taagaaatcg atcgagcgta ccagccgttg ggctgagcgt ggtttgaagg ctcaccgtcg
    10561 tccacatgac caaggtttgt ttggaattgt gcaaggtgca ggatttgaag accttcgccg
    10621 ccaatcagct catgatcttg tcagcatgga tttctcaggc tactctatcg gtggtttggc
    10681 agtgggagaa acccatgaag agatgaatgc ggtcttggac tttacaactc aactgctgcc
    10741 tgaaaataaa cctcgttatc tgatgggtgt gggagcgcca gatagcttga tcgatggggt
    10801 cattcgtggg gtggatatgt ttgactgtgt cttaccgact cgaattgctc gtaacgggac
    10861 ttgtatgacc agtcaaggac gtttggttgt gaaaaatgcc cagtttgctg aggactttac
    10921 gccactggat cctgagtgtg attgctacac atgtaataac tatacacgcg cttaccttcg
    10981 tcacctgctc aaggctgatg aaacctttgg tatccgcttg actagctacc acaatcttta
    11041 cttcttgctt aacctgatga agcaagtgcg acaagccatc atggatgaca atctcttgga
    11101 attccgtgag tattttgtgg aaaaatatgg ctataataag tcaggacgta atttctaaaa
    11161 tggaattgat ataaaaaaat cctaagtttt ctcttaggat ttttcttctt tttttgatag
    11221 aataaagtgt acaatgaaag gaagaataaa ctcgtatgcg cattaaatgg ttttccttga
    11281 ttaggattat aggtttactt ttggtactct tgtatcactt ctttcagacg atctttcctg
    11341 gaggattttt cggggtagat gtctttttca cattttcagg tttcctgatt acagctctac
    11401 tcattgaaga attttctaag aacaatgaga ttgatttgat aggatttttt agaagacgct
    11461 tttatcggat tgtgccacct gtggttttga tggtcttggt gaccatgcct tttactttct
    11521 tggttcgcca agactatgtt gctggaattg gtggccagat tgcgggcgtc ttaggcttta
    11581 tgaccaactt ctatgaactc ctaacaggtg ggagttatga atctcagttc attcctcatt
    11641 tgtttgttca taattggagt ttggcagttg aggttcacta ctatattctt tggggattgg
    11701 cagtttggtt cttatccaaa caagctaaat caaatggtca gttgaagggg atggtctttc
    11761 tcttatctgc tgttgccttc ttgatcagtt tcttctccat gtttattggt agttttctag
    11821 tgacctctta ttcctctgtt tatttctcca gtttaactca tgtctatcca ttctttttag
    11881 gaagtatgtt agcaactatt gtaggcgttc gtcagacgac ttccctcgtc aagcagttgg
    11941 ataaaatctg ggatttacga aagactttgg tagtttttgg aggaggcttt ggtttcctag
    12001 ttcttttgac tttctttgtc aaattcactt atctttttgc ctatcttatc ggcttcttac
    12061 ttgccagtct tgcagctctt gccatgattc tggcggcgcg tgtcttacat gaaaagacac
    12121 atcatataca ggagtcgaag attatcagct ttttagcgga tactagctat gcggtttatc
    12181 ttttccattg gcctttctat atcattttct cacagttgac atcaaatctt cttgctgtat
    12241 tactgactct gatttgttct tatggctttg ccagtctgtc attttatgta ttggaacctt
    12301 ggattgcagg caagaacaca cctattgtcc aaacccttcg tcccctgcct tatattcacg
    12361 caattcttgc agcaggtaca ggaatcttga ccatcattgt ctgcacggtg accttgttgg
    12421 caccacaagt gggagcgttt gagacagact tgactgtcaa tggcttgaag caagctgcaa
    12481 caaatattgg ccagaccaag gtgatggcag aacgggcaga tgcaaacagt ttgggaattg
    12541 ctgatggcac tatgttaatt ggtgactcag tggctttaag ggcaaataca gcactacaga
    12601 cagctcttcc tggagcacag attaacgcgc aggtcagcgt aacaaccaag accgcaaatg
    12661 aaatcatgct aaataatagc cagaataaat ttttacctaa gacggtggtc attgcgactg
    12721 gggtaaataa tcctgagaat tacaaggatg actgggacag tatcgtgaaa aatcttccta
    12781 agggacacca tatgattttg gtgactcctt atgagggaga taagacaaaa gagacctatg
    12841 ccatcgttga gaaggctgct gcctatatga gagaattggc agagaagaca ccttacatta
    12901 cgatagcaga ttggaatcaa gttgcgaaag agcatccaga aatttgggct ggaacagacc
    12961 aggttcattt cgggagtgag agtagcacta tcgaagcagg agcaaaattg tatgcagata
    13021 cgattgccac agctttgcag acagctcaag acaagccggt taaatcaaaa taacttgtat
    13081 taaaaaagag aagagttgga gaaatccagc tcttttaaaa tatctccaaa aaataggtct
    13141 ataccattta caaataaaaa agaaaggttt ataatgtaat tgacataata aattgtagaa
    13201 tcaatctttt aaggaggtta acattatgcc taactatatt aaagcggatc agtttttcta
    13261 cccacacgga gttcgtcgag gtggttactt ggaacttgtg gacggcaagt ttgggaaaca
    13321 tgtagagcag attcctgaag gggctgaggt gattgactat acaggttata gcattgcccc
    13381 aggtcttgtg gatactcata ttcatggata tgcaggtgta gatgtgatgg acaacaacat
    13441 tgaaggtaca ttgcatacta tgagtgaagg acttcttagt accggtgtta ccagtttctt
    13501 acccacaact ttaacagcca cttatgagca attgcttgca gtcactgaaa atcttggaaa
    13561 ccattataaa gaagcaacag gtgctaagat tcgtgggatt tattatgaag gtccatattt
    13621 cacagaaact tttaaggggg cacaaaatcc aacttatatg agagacccgg gtgttgagga
    13681 gtttcattct tggcaaaaag cggcaaatgg cttgcttaat aaaattgccc ttgcaccaga
    13741 acgtgatggg gtggaagact ttgttcgtac agttacgggc gaaggtgtga cggttgctct
    13801 tggacattca aacgcgactt ttgatgaagc caaaaaagca atcgatgctg gagcgagtgt
    13861 ttgggtgcat gcctacaatg gaatgcgtgg gttgactcac cgtgaattgg ggatggttgg
    13921 agccatgtac caattgccac atacctatgc agagttgatc tgtgatggtc accacgtaga
    13981 tccaaaggct tgcgaaattc ttatcaaaca aaaaggaaca gaaaacatcg ctcttatcac
    14041 agactgtatg acagctgggg gattggaaga cggagattat atgttgggag aattcccagt
    14101 tgtcgttgca aatggaactg cacgcctcaa atcgacaggt aacttggcag gttctatcct
    14161 caaactcaaa gatggtttga agaatgtggt cgaatgggga attgcgaatc cgcatgaagc
    14221 agtcatgatg gccagcttca acccagctaa atccgttcac atcgatgacg tctgtggcca
    14281 aatccgtgaa ggctacgacg ctgacttcat cgtattagat aaagatttgg aattggtagc
    14341 aacctaccta gatggcgtaa aacgttatca agcataagag agaaagcaga agttagagac
    14401 taacttctgc ttttttatgc agggtacttt actggtaaat aaaaagttaa aaaaatcaca
    14461 aaaaaagctt gaagaaacaa agaaaaaggc ttacaattga actataaata ttacaaataa
    14521 aaaaacggag gagtgcttta tgaaagccta tacttatgtt aaaccaggac ttgcttcttt
    14581 tgttgatgta gacaaaccag ttattcgcaa gccaacagac gctattgtgc gtattgtaaa
    14641 aaccactatt tgtggaacag acctccatat tatcaaaggg gatgttccta cttgccaaag
    14701 tggtaccatt cttggccacg aagggattgg gattgttgaa gaagttgggg aaggagtttc
    14761 caacttcaaa aaaggtgaca aggtcttgat ttcttgcgtc tgtgcctgtg gtaaatgcta
    14821 ctactgtaaa aaaggaattt atgctcactg tgaagacgaa gggggctgga ttttcggtca
    14881 cttgattgat ggtatgcagg ctgaatatct acgtgtccct catgcagata atactcttta
    14941 ccatactcca gaagacttgt cagatgaagc tttggttatg ctgtcagaca ttctgcctac
    15001 tggatatgaa attggtgtct taaaagggaa agtagaacct ggttgcagcg tagccattat
    15061 tggttcaggt ccagttggat tggctgctct tttaacagcc caattctatt caccagctaa
    15121 attgattatg gtagacctag acgataaccg cttggaaact gccctatcat tcggtgcgac
    15181 tcataaggtt aattcttcag accctgaaaa agccattaaa gaaatttatg atttgacaga
    15241 tggtcgtggt gtggatgtcg ctatcgaagc tgttggtatt cctgcaacat ttgatttctg
    15301 tcaaaagatt atcggtgtag acggaacggt tgccaactgt ggtgtgcatg gtaaaccagt
    15361 tgaattcgat ttagataaac tttggattcg caacatcaat gtaacaactg gtttggtatc
    15421 tacaaatacg actccacaat tgttgaaagc acttgaaagt cataagattg aaccggaaaa
    15481 attggtaact cactatttca aactcagtga aattgaaaaa gcctacgaag tcttcagtaa
    15541 ggcagcagac caccatgcca ttaaggtcat tatcgaaaac gatatctcag aagcctaagt
    15601 agtaaaaata tttttgtaca taagtaaata gaaattcagt catccatcag atggctggat
    15661 tttttatcaa aaaattaaga aatgagcata tttctttcct tgtctggcgg aattggttat
    15721 aatatacggt acaaaggaat gaatgaatat gtatcgtgtt atagaaatgt acggagattt
    15781 tgaaccgtgg tggttcttag aaggttggga agaagatatt gtagcaagta gaaaatttga
    15841 ccagtattat gatgctctca aatactacaa aacttgctgg tttagattgg aacaagaatc
    15901 gcctctttat aaaagtagaa gcgacttgat gaccattttt tgggacccgg aagaccaacg
    15961 ctggtgtgat gaatgtgatg agtatttaca acaataccat tctttggctc ttttgcagga
    16021 tgagcaggtt atcccagacg aaaaactacg ctcaggctat gaaaaacaaa ccagtcagga
    16081 aaggaatcgt tcttgccgta tgaaattaaa atagagaaaa gtaacttttt tggagttgct
    16141 ttttttattt ttctaactct ttgcgaatag tataggtgag gaggtaagta tggttcaaga
    16201 aattgcacaa gaaatcattc gttcagctcg gaaaaaaggg acgcaggata tctattttgt
    16261 ccctaagtta gacgcctatg agcttcatat gagggtagga gacgagcgct gtaaaattgg
    16321 tagctatgat tttgaaaagt ttgcagccgt tatcagtcac tttaagtttg tggcgggtat
    16381 gaatgtggga gaaaaaagac gtagtcaact gggttcctgt gattatgcct atgaccataa
    16441 gatagcgtct ctacgtttat ctactgtagg cgattatcgg gggcatgaga gtttggttat
    16501 ccgtttgttg cacgatgagg agcaggacct gcatttttgg tttcaggata ttgaagaatt
    16561 aggcaagcag tacaggcaac ggggactcta tctttttgct ggtccggttg ggagtggtaa
    16621 gacgaccttg atgcatgaat tgtccaagtc actctttaaa ggacagcaag ttatgtccat
    16681 cgaagatcct gtcgaaatca agcaggacga catgcttcag ttgcagttga acgaagcaat
    16741 cggcctaacc tatgaaaatc taatcaaact ttccttgcgt catcgaccag atctcttgat
    16801 tatcggagaa attcgtgaca gcgagacggc gcgtgcagtg gtcagagcta gtttgacagg
    16861 tgcgacagtc ttttcaacca ttcacgccaa gagtatccga ggtgtttatg agcgtctgct
    16921 ggagttgggt gtgagtgaag aagaattggc agttgttctg caaggagtct gctaccagag
    16981 attaatcggg ggaggaggaa tcgttgactt tgcaagcaga gattatcaag aacaccaagc
    17041 agccaagtgg aatgagcaaa ttgaccagct tcttaaagat ggacatatca caagtcttca
    17101 ggctgagacg gaaaaaatta gctacagcta agcaaaaaaa tatcatcacc ctatttaaca
    17161 atctcttttc tagcggtttt catctggtgg agactatctc ctttttagat aggagtgctt
    17221 tgttggacaa gcagtgtgtg acccagatgc gtgtgggctt gtctcagggg aaatcattct
    17281 cagaaatgat ggaaagtttg ggatgttcaa gtgctattgt cactcagtta tccctagctg
    17341 aagttcatgg caatctccac ctgagtttgg gaaagataga agaatatctg gacaatctgg
    17401 ctaaggtcaa gaaaaaattg attgaagtag cgacctatcc cttgattttg ctgggttttc
    17461 ttctcttaat tatgctgggg ctacggaatt acctgctccc acaactggat agtagcaata
    17521 ttgccaccca aattatcggt aatctgcccc aaatttttct aggcatggta gggcttgttt
    17581 ccgtgcttgc ccttttagca ctcacttttt ataaaagaag ttctaagatg agtgtctttt
    17641 ctatcttagc acgccttccc tttattggaa tctttgtgca gacctacttg acagcctatt
    17701 atgcacgtga atgggggaat atgatttcac agggaatgga gttgacgcag atttttcaaa
    17761 tgatgcagga acaaggttcc cagctcttta aagaagtcgg tcaagatctg gctcaaaccc
    17821 tgaaaaatgg ccgtgaattt tctcagacga taggaaccta tcctttcttt aggaaggaat
    17881 tgagtctcat catagagtat ggggaagtta agtccaagct gggtagtgag ttggaaatct
    17941 atgctgaaaa aacttgggaa gcctttttta cccgagtcaa ccgcaccatg aatttggtgc
    18001 agccactggt ttttatcttt gtggcactga ttatcgtttt actttatgcg gcaatgctca
    18061 tgcccatgta tcaaaatatg gaggtaaatt tttaaaatga aaaaaatgat gacattcttg
    18121 aaaaaagcta aggttaaagc ttttacattg gtggagatgt tggtggtctt gctgattatc
    18181 agcgtgcttt tcttgctctt tgtacctaat ctgaccaagc aaaaagaagc agtcaatgac
    18241 aaaggaaaag cagctgttgt taaggtggtg gaaagccagg cagaacttta tagcttagaa
    18301 aagaatgaag atgctagcct aagaaagtta caagcagatg gacgcatcac ggaagaacag
    18361 gctaaagctt ataaagaata caatgataaa aatggaggag caaatcgtaa agtcaatgat
    18421 taaggccttt accatgctgg aaagtctctt ggttttggga cttgtgagta tccttgcctt
    18481 gggcttgtcc ggctctgtcc agtccacttt ttcagcggta gaggaacaga ttttctttat
    18541 ggagtttgaa gaactctatc gggaaaccca aaaacgcagt gtagccagtc agcaaaagac
    18601 tagtctgaac ttagatgggc agacgcttag caatggcagt caaaagttgc cagtccctaa
    18661 aggaattcag gccccatcag gccaaagtat tacatttgac cgagctgggg gcaattcgtc
    18721 cctggctaag gttgaatttc agaccagtaa aggagcgatt cgctatcaat tatatctagg
    18781 aaatggaaaa attaaacgca ttaaggaaac aaaaaattag ggcagtgatt ttactggaag
    18841 cagtagtcgc tctagctatc tttgccagca ttgcgaccct ccttttggga caaattcaaa
    18901 aaaataggca agaggaagca aaaatcttgc aaaaggaaga agtcttgagg gtagctaaga
    18961 tggccctgca gacggggcaa aatcaggtaa gcatcaacgg agttgagatt caggtatttt
    19021 ctagtgaaaa aggattggag gtctaccatg gttcagaaca gttgttggca atcaaagagc
    19081 cataaggtca aggcttttac cttgttagaa tccctgcttg ccctcattgt catcagtggg
    19141 ggattactcc tttttcaagc tatgagtcag ctcctcattt cagaagttcg ctaccagcaa
    19201 caaagcgagc aaaaggagtg gctcttgttt gtggaccaac ttgaggtaga attagaccgt
    19261 tcgcagttcg aaaaagtaga aggcaatcgc ctatacatga agcaagatgg caaggacatc
    19321 gccatcggta agtcaaagtc agatgatttc cgtaaaacga atgctcgtgg tcgaggttat
    19381 cagcctatgg tttatggact caaatctgta cggattacag aggacaatca actggttcgc
    19441 tttcatttcc agttccaaaa aggcttagaa agggagttca tctatcgtgt ggaaaaagaa
    19501 aaaagttaag gcaggtgttc tcctctacgc agtcaccata gcagccatct ttagtctttt
    19561 gttgcaattt tatttgaacc gacaagtcgc ccactatcaa gactatgctt tgaataaaga
    19621 aaaattggtt gcttttgcta tggctaaacg aaccaaagat aaggttgagc aagaaagtgg
    19681 ggaacagttt tttaatctag gtcaggtaag ctatcaaaac aagaaaactg gcttagtgac
    19741 gagggttcgt acggataaga gccaatatga gtttctgttt ccttcagtca aaatcaaaga
    19801 agagaaaaga gataaaaagg aagaggtagc gaccgattca agcgaaaaag tggagaagaa
    19861 aaaatcagaa gagaagcctg aaaagaaaga gaattcatag tcaattcaac tataatgcgt
    19921 tgaatccaga atagtccact gtagtttcta gaaaattgct ggaaatggat gttaagctcc
    19981 aattcatttg tttatatctt atttcagttt actatacttt gtgctaaatt aaagatatga
    20041 aacatgattt taaccacaaa gcagaaactt tcgattcccc taaaaatatc ttcctcgcaa
    20101 acttggtatg tcaagcagcc gagaaacaga ttgatcttct atcagacaaa gaaattttag
    20161 atttcggtgg tggcacgggt ctattagcct tgcccctaac ccctagccaa gcaggctaag
    20221 tcagtcactc ttgtagacat ttctgagaaa atgttggagc aagctcgttt gaaagtggag
    20281 cagcaagcaa tcaagaatat ccagtttttg gagcaagatt taccgaaaaa tcccttggag
    20341 aaagagtttg attgccttgc tgttagtcgg gttcttcatc atatgcctga tttggatgcg
    20401 gctctctcac tgtttcatca acatttgaag gaagatggga aactcatcat tgctgatttt
    20461 accaagacag aagctaatca tcatggattt gatttagctg aactggaaaa caagctaatt
    20521 gagcatggtt tttcatctgt gcatagtcag attctctata gtgctgaaga cctgtttcaa
    20581 ggaaatcact cagaattctt tttaatagta gcccaaaaat cactcgccta gtcagggagt
    20641 gatttttcta taaggatgga aaaaagaagg gaaatttggt aagataggaa tatggatttt
    20701 gaaaaaattg aacaagctta tacctattta ctagagaatg tccaagtcat ccaaagtgat
    20761 ttggcgacca acttttatga cgccttggtg gagcaaaata gcatctatct ggatggtgaa
    20821 actgagctaa accaggtcaa ggagaacaat caaaccctta agcgtttagc actacgcaaa
    20881 gaagaatggc tcaagaccta ccagtttctc ttgatgaagg ctgggcaaac agaacccttg
    20941 caggccaatc accagtttac accggatgct attgctttgc ttttggtgtt tattgtggaa
    21001 gagttgttta aagaggagga aattactatc ctcgaaatgg gttctgggat gggaattcta
    21061 ggcgctattt tcttgacctc gcttactaaa aaggtggatt acttgggaat ggaagtggat
    21121 gatttgctga ttgatctggc agctagcatg gcagatgtaa ttggtttgca ggctggcttt
    21181 gtccaaggag atgccgttcg cccacaaatg ctcaaagaaa gcgatgtggt catcagtgac
    21241 ttgcctgtcg gctattatcc tgatgatgcc gttgcgtcgc gccatcaagt tgcttctagc
    21301 caagaacata cttacgccca tcacttgctc atggaacaag ggcttaagta cctcaagtca
    21361 gacggatacg ctatttttct agctccgagt gatttgttga ccagtcctca aagtgatttg
    21421 ttaaaagaat ggctgaaaga agaggcgagt ctggttgcta tgattagtct gcctgaaaat
    21481 ctctttgcta atgccaaaca atctaagact atttttatct tacagaagaa aaatgaaata
    21541 gcagtagagc cttttgttta tccacttgct agcttgcaag atgcaagtgt tttaatgaaa
    21601 tttaaagaaa attttcaaaa atggactcaa ggtactgaaa tataaaatag attttgttat
    21661 aatagttgaa aacgcttaaa aaggggtatc atgttatgac aaaaacaatt gcaatcaatg
    21721 caggaagttc aagtttgaaa tggcaattat acttaatgcc agaagaaaaa gtattggcga
    21781 aaggtttgat tgaacgtatc ggtttgaaag attcaatttc aactgtaaaa tttgacggcc
    21841 gttctgaaca acaaattttg gatattgaaa atcatataca agccgttaaa attttattgg
    21901 atgacttgat tcgtttcgat attatcaagg cttatgacga gattacaggt gttggacatc
    21961 gtgttgttgc tggtggagaa tatttcaaag aatcaacagt tgttgaggga gatgttttag
    22021 aaaaagttga agagttgagt ttgttggctc ctctacacaa cccggccaat gcagcaggtg
    22081 ttcgtgcctt caaggaattg ttgccagaca ttaccagtgt agttgttttt gatacttcct
    22141 tccacacaag tatgccagag aaagcttatc gctaccctct accaacaaaa tattacacag
    22201 aaaacaaggt tcgtaaatac ggtgctcatg gtacaagtca ccagtttgta gcaggagaag
    22261 ctgcaaaact cttgggacgt ccattagaag acttgaagtt aattacctgt catattggta
    22321 acggaggctc aattacagct gtgaaagccg gcaaatctgt agacacttct atggggttca
    22381 ctcctcttgg tggtattatg atgggaacgc gtacagggga tattgatcca gctatcattc
    22441 cttatttaat gcaatataca gaggatttta acacaccaga agatatcagt cgtgttctta
    22501 accgtgaatc aggtcttttg ggagtttctg ctaattctag cgatatgcgc gatatagaag
    22561 cagctgtagc agaagggaat cacgaggcta gcttggctta tgaaatgtat gttgaccgta
    22621 tccaaaaaca tatcggtcag taccttgcag tgctaaatgg agcagatgcc attgttttca
    22681 cagcaggtgt cggtgaaaat gcagagagtt tccgtcgtga tgtaatctca gggatttcgt
    22741 ggtttggttg tgatgttgat gatgaaaaga atgtctttgg cgttacagga gacatctcaa
    22801 cagaggcagc taaaatccgt gtcttggtta ttccaacaga tgaagaatta gtcattgccc
    22861 gtgacgttga acgcttgaaa aaataagtga aactaaaaaa atattcaata caaggagttg
    22921 ggaaagttat ttttccagct tctttttctg atgaaattgt ccaaaacctt gctatgattg
    22981 gcttttttga aaaatatggt ataatagtag taatttaata gatggagttg agttttgaag
    23041 aaaaactttc gtgtaaaaag agagaaagat tttaaggcga ttttcaagga ggggacaagt
    23101 tttgctaatc gcaaatttgt ggtctaccaa ttagaaaacc agaaaaaccg ttttcgagta
    23161 ggtctatcag ttagcaaaaa actggggaat gccgtcacta gaaatcaaat taagcgacgg
    23221 attcggcata ttatccagaa tgcaaaaggg agtctggtag aagatgtcga ctttgttgtc
    23281 attgctcgaa aaggagtcga aaccttggga tacgcagaga tggagaaaaa tctactccat
    23341 gtattaaaat tatcaaagat ttaccgggaa ggaaatggga gtgaaaaaga aactaaagtt
    23401 gactagtttg ctaggactgt ctctgttaat catgacagcc tgtgcgacta atggggtaac
    23461 tagcgatatt acagccgaat cggctgattt ttggagtaaa ttggtttact tctttgcgga
    23521 aatcattcgc tttttatcgt ttgatattag tatcggaatg gggattattc tctttacggt
    23581 cttgattcgt acagtcctct tgccagtctt tcaggtgcaa atggtggctt ctaggaaaat
    23641 gcaggaagct cagccacgca ttaaggcgct tcgagaacaa tatccaggtc gagatatgga
    23701 aagcagaacc aaactagagc aggaaatgcg taaagtattt aaagaaatgg gtgtcagaca
    23761 gtcagactct ctttggccga ttttgattca gatgccggtt attttggccc tgttccaagc
    23821 cctatcaaga gttgactttt taaagacagg tcatttctta tggattaacc ttggtagtgt
    23881 ggatacaacc cttgttcttc cgattttagc agcagtattc acctttttaa gtacttggtt
    23941 gtccaacaaa gctttgtctg agcgaaatgg cgctacgact gcgatgatgt atgggattcc
    24001 agtcttgatt tttatctttg cagtttatgc gccaggtgga gtcgccctat actggacagt
    24061 gtctaatgct tatcaagtct tgcaaaccta tttcttgaat aatccattca agattatcgc
    24121 agagcgcgag gccgtagtac aggcacaaaa agatttggaa aatagaaaaa gaaaagccaa
    24181 gaaaaaggct cagaaaacga aataaataag gaggaatctg gtagtggtag tatttacagg
    24241 ttcaactgtt gaagaagcaa tccagaaagg attgaaagaa ttagatattc caagaatgaa
    24301 ggctcatatc aaagtcattt ctagggagaa aaaaggcttt cttggtctat ttggtaaaaa
    24361 accagcccaa gtggatattg aagcgattag tgaaacgact gttgtcaaag caaatcaaca
    24421 ggtagtaaaa ggcgttccga aaaaaatcaa tgatttgaac gagcctgtga agacggttag
    24481 tgaagaaacc gttgaccttg gtcatgtggt tgatgctatt aaaaaaatag aggaagaagg
    24541 tcaaggtatt tctgatgaag tcaaggctga aatcttaaaa catgaaagac atgccagcac
    24601 tatcttagaa gaaactggtc acattgagat tttaaatgaa cttcaaatcg aggaagcgat
    24661 gagggaagaa gcaggcgctg atgaccttga aactgagcaa gaccaagctg aaagtcaaga
    24721 actagaagac ttgggcttga aagttgaaac gaactttgat attgaacaag tagctacgga
    24781 agtaatggct tatgttcaaa cgattattga tgacatggat gttgaggcta cactttcaaa
    24841 tgattataac cgtcgtagca tcaatctaca aattgacacc aacgaaccag gtcgtattat
    24901 cggctaccat ggtaaagtct tgaaggcctt gcaactgttg gctcaaaatt atctttacaa
    24961 ccgctattcc agaaccttct acgttacaat caatgtcaat gattatgtcg aacaccgtgc
    25021 agaagtcttg cagacctatg cgcaaaaatt ggcgactcgt gttttggaag aagggcgcag
    25081 tcataaaaca gatccaatgt caaatagcga acgcaagatt atccatcgta ttatttcacg
    25141 tatggatggc gtgactagtt actctgaagg tgatgagcca aatcgctatg ttgttgtaga
    25201 tacagaataa gtaaaatcag gtttatcctg attttttgct agttagagga ggttaaactg
    25261 atgttgaata agataagaga ctatttagac tttgctggtt tgcagtaccg taatcctgat
    25321 aaagcgggag cagagcgaga gaagatgctg gcattccgcc acaaaggaca agaggcccga
    25381 aaggttttta cagaactggc caaagccttt caagcaagcc atccagaatg gcaactccaa
    25441 cagactagcc agtggatgaa tcaggcccag cgtttgagac cacatttttg ggtttatcta
    25501 cagagagacg gacaagtgac agaacctatg atggccttac gtttgtatgg gacatctact
    25561 gactttggaa tttctttgga agtcagtttc atcgaacgta agaaggatga gcaaacactg
    25621 ggcaagcagg ccaaagtttt agacattcca accgttaaag ggatttatta tctaacctac
    25681 tctaatggtc aaagtcaacg gtgggaggcg aatgaagaaa agcgtcgtac tttacgcgag
    25741 aaggtgagaa gtcaagaagt tcgaaaagtt ttagtgaagg tagatgttcc tatgacagaa
    25801 aattcgtctg aagaagaaat cgtagaaggc ttattgaagt cttattctaa aattcttccc
    25861 tattatctag ctacgagaaa ataagataat ttgtaaaaca tcataaatca tacagtccaa
    25921 gagtgaacag tccgctgtgt aattcttggt ctttttgttt gcgctttcgc attatataat
    25981 aaacttacaa aaacaattca aaaggagaac aattatggaa gtcgtttcaa gtgttctaaa
    26041 ttggttttct agcaatattt tgcagaatcc cgcatttttc gtaggtttat tggtgttgat
    26101 aggatatgca cttttgaaaa aacctgccca tgacgttttt tcagggtttg ttaaagcaac
    26161 agtagggtat atgttgctta acgtgggtgc tggtggtttg gttacaacct ttcgtccaat
    26221 cttagcagct cttaactaca aattccaaat tggtgcagcg gttatcgacc cttactttgg
    26281 acttgctgca gcaaacaaca aaattgtagc agagtttcca gattttgttg gaactgcaac
    26341 tacagctcta ttgattggtt ttggaataaa tatcttgctc gtagctcttc gaaagattac
    26401 gaaggtaaga accctcttta ttactggtca catcatggta caacaagctg caacagtatc
    26461 tcttatggtt ctattcttag taccacaatt gcgcaatgct tacggtacag cagcgattgg
    26521 tatcatctgt ggactttact gggcagttag ttcaaatatg actgttgagg caactcaacg
    26581 cttgactggt ggtggcggat ttgcgattgg tcaccaacag caatttgcaa tctggtttgt
    26641 agataaagta gcaggacgct ttggtaagaa agaagaaagt ttagacaatc ttaaattacc
    26701 taagttcctc tcaatcttcc acgatacagt tgttgcatct gctaccttga tgctcgtatt
    26761 cttcggagcc attcttttaa tcttgggtcc agacattatg tctaataaag aagtcatcac
    26821 ttcaggaact ctattcaatc ctgctaaaca agatttcttt atgtacatta tccaaacagc
    26881 ctttaccttc tcagtttact tgttcgtttt gatgcaaggt gtccgaatgt tcgtatctga
    26941 gttgacaaac gccttccaag gtatttcaaa caaattgttg ccaggttcat tcccagcggt
    27001 tgacgttgca gcttcttatg gatttggttc tccaaatgct gtcttgtcag gatttacctt
    27061 tggtttgatt ggtcaattga ttacaattgt tttgctcatc gtctttaaaa atccgattct
    27121 tattattaca ggatttgtac cagtgttctt tgacaatgca gccattgcgg tctacgctga
    27181 taaacgcggc ggatggaaag cggctgttat cctttccttt atatcaggtg tccttcaagt
    27241 tgctctagga gctctttgtg tggcccttct cgatttggca tcttatggtg gctaccatgg
    27301 aaatatcgac tttgaattcc catggcttgg atttggatat atcttcaaat accttggtat
    27361 tgttggttat gtacttgtgt gtctcttctt gcttgttatt cctcaacttc aatttgccaa
    27421 agcaaaagat aaagagaaat attacaacgg tgaagttcaa gaagaagctt agtatctaga
    27481 aaaggagaaa taaaatggtt aaagtattag cagcgtgcgg aaatggaatg ggttcatcaa
    27541 tggttatcaa gatgaaggtt gaaaatgctc tccgtaagct taatcaaaca gattttacag
    27601 tcaattcatg cagtgtcggt gaagctaaag gtttagcagt aggatatgac atcgtaatcg
    27661 cttctcttca tttgattcaa gaattggaag ggcgaactaa tgggaagtta attgggcttg
    27721 ataacttgat ggatgataaa gaaatcaccg aaaaactcag tcaagcacta cagtaaaagg
    27781 ttggaggggg ctggacagaa actgagagtt atcgtttctg tccttctccc tctttaaata
    27841 aaggaggcag atatgaattt aaaacaagct ttaattgaca atgactcgat ccgactaggt
    27901 ttagaggcta acaattggaa agaagcagtc aaggtagcag tagatccctt aattgaaagt
    27961 ggggcaattt tgccagagta ttacgatgct atcattgaat cgactgaaga gtatgggcct
    28021 tactatatct tgatgccagg tatggctatg ccccacgcta gacctgaagc aggtgtgcaa
    28081 agtgatgcct tttcattgat taccttacaa aatcctgttg tattttcaga tgggaaagag
    28141 gtatctgttt tgttggcact agcagcaaca agttcaaaaa ttcacacaag tgtagccatt
    28201 ccacaaatta ttgccctatt tgaattagaa gattctattg cacgtttaca ggcttgccag
    28261 actaaagaag atgtcttggc tatgattgaa gaatctaagg atagccctta tctcgaagga
    28321 ttggatttgg aaagttagaa agaggaataa agaaatgaca aaaagaatac ctaatttaca
    28381 agttgcatta gaccattcag acttgcaagg agcgattaaa gcagctgttt ctgttggtca
    28441 ggaagtagat attatcgaag ctggaactgt ttgcttgctt caagttggaa gtgaactggc
    28501 tgaagtcttg cgtagccttt tcccagataa gattattgtg gcagacacaa aatgtgctga
    28561 tgctggtgga acagttgcta aaaataatgc ggttcgtgga gcagactgga tgacttgtat
    28621 ctgttgtgca accatcccta ctatggaagc agctctaaag gctatcaaga ctgaacgagg
    28681 agaacgaggc gaaatccaga tcgagcttta tggcgattgg acttttgaac aagctcagct
    28741 ttggctagat gcaggtatct cacaagctat ttatcaccaa tctcgtgatg ctcttcttgc
    28801 tggtgaaact tggggtgaaa aagaccttaa taaggttaaa aaactcattg acatgggctt
    28861 ccgtgtatct gtaacaggtg gtctagatgt agatactctc aaactctttg aaggtattga
    28921 tgtctttacc tttatcgcag gtcgtggaat tacagaggct gtggatccag caggagcagc
    28981 gcgtgccttc aaggatgaaa tcaaacgaat ttgggggtaa atcatggtac gtccaattgg
    29041 aatttatgaa aaggcaaccc caacacactg tacttggcta gaacgtttaa attttgccaa
    29101 ggagttaggc tttgattttg tcgagatgtc tattgacgaa cgtgacgagc gtttagcaag
    29161 acttgactgg agtaaggaag aacgcttgga agttgtcaaa gcaatctatg aaactggtgt
    29221 tcgtattcct tctatctgtt tttcaggcca tcgtcgctac ccattgggtt caaaagatcc
    29281 agttctagag gaaaaatctc tagaactcat gaaaaaatgt atcgaattag ctcaagactt
    29341 gggagttcgt acgattcaat tagctggtta cgatgtttac tatgaggaaa agtcacccca
    29401 gacacgccaa cgttttatca aaaatttgag aaaagcctgt gactgggctg aagaagctca
    29461 ggtggtactt gctattgaaa ttatggatga tcctttcatc agtagcatcg aaaaatattt
    29521 ggctatagaa aaagagattg actctccctt cctctttgta tatccagata ttggtaatgt
    29581 gtctgcatgg cataatgata tctatagtga gttttatctt ggtcatcatg ccatcgcagc
    29641 tctccatctc aaggatactt atgcagtgac agaaagttca aagggccagt tccgagatgt
    29701 acctttcggg caaggttgtg tcaaatggga agaagctttc gatattttaa aggaaaccaa
    29761 ttataatgga cctttcctaa tcgaaatgtg gtctgaaaat tgtgaaacag tagaagaaac
    29821 acgcgcagcc attcaagagg cgcaagcttt tctctatcca ctcattaaga aagcaggttt
    29881 gatgtaagat gaatcaagta atcaatgcta tgcgtaaacg agtctgtgat gccaatcaat
    29941 cattgccaaa acatggactt gtcaaattta cctgggggaa tgtatctgaa gttaatcgcg
    30001 aactcggtgt cattgttatc aaaccatcag gcgtggatta tgacgaattg acacctgaaa
    30061 acatggtagt gactgatcta gatggtaaga tcctagaagg ggatttaaga ccatcttccg
    30121 acctcccaac tcatgtgcaa ttatataaga cttggtcaga aattggtagt gtggttcaca
    30181 cccattcgac agaagctgtt ggttgggctc aggcaggtcg tgatattcct ttctacggaa
    30241 caacccatgc agattatttc tacggttcaa tcccttgcgc ccgtagtttg accaaggacg
    30301 aagtagaagt ggcctatgaa aaagatactg gcctggttat cgtagaagag tttgaacatc
    30361 gcggacttaa cccggttgaa gtaccaggaa ttgttgtacg caatcacggt ccattcacct
    30421 ggggcaaaaa tccagagaat gctgtttatc actctgtcgt actagaggaa gtatcaaaga
    30481 tgaatcgctt tacagaacaa atcaatccaa gagttggacc tgctccccag tacatactag
    30541 aaaaacacta ccaacgtaaa catggaccaa atgcttatta tggtcaaaag taagaacgat
    30601 gaaggaggag aaaaagataa atttagctcc tctttttaca tttgattttt attgagagta
    30661 aagttggagt tgaagtaatt ttaaaagatt ttttagaaat agcgcttgat atatatatgg
    30721 taaaataaaa agaattgctg tgatatcaat agatttgggg gattttttaa tatggtactg
    30781 gataaggcaa gttgtgattt gcttcaatat ttgatggatc aagaaacgtc caaaacgatt
    30841 atggcgattt cgaaagattt gaaagagtca agaaggaaaa tttattatca cattgacaaa
    30901 atcaatgctg ctctgggtga cgaggcgctt cacatcatta gtattccacg aattggtatt
    30961 cacttaacgg aagagcagag agatgcttgt tgtaaactat tatcggaagt agattcgtac
    31021 gattatatca tgagtgcgca tgaacgtatg atgataatgt tactatggat aggtatttct
    31081 aaagaacgta ttacgattga aaaattgata gagttaacag aggtatctag gaatactgtt
    31141 ctcaatgatt tgaatagtat tcgttatcaa ctaactttgg aacaatatca ggtgatcttg
    31201 caagtgagca agtcacaggg atacaacctt catgcccacc ctcttaataa aattcagtat
    31261 cttcaatcgc ttctatatca tatttttatg gaagaaaatg ccacttttgt atctatttta
    31321 gaagataaga tgaaagagag gttagatgat gagtgtttgc tttctgttga aatgaaccaa
    31381 ttttttaagg aacaggttcc tttagttgaa caagatttag ggaagaaaat aaaccatcat
    31441 gaaataactt ttatgttgca ggttctacct tatttgctgt taagctgtca taatgttgaa
    31501 cagtatcaag aaagacatca ggatatagag aaagaatttt ctttgataag aaaaagaata
    31561 gagtatcagg tgtctaagaa attaggagaa cggttgtttc aaaagtttga aatttctttg
    31621 tcaggacttg aagtttctct tgtagctgtt ctcctcctct cctatcgtaa agatttggat
    31681 attcatgcag aaagtgatga ttttcggcaa ttaaaacttg ctttagaaga atttatctgg
    31741 tattttgaat cacaaatccg aatggagatt gagaacaagg atgatttgtt acgaaatttg
    31801 atgatccact gtaaagcctt gttatttaga aagacttacg gtattttttc taaaaatcct
    31861 ctaacaaaac aaattcgatc caagtatgga gaattatttt tagtcactag aaaatctgcg
    31921 gaaattttag aaggagcatg gtttattcgg ctaacagacg atgatattgc ctatttgacg
    31981 attcatattg gaggattttt aaaatataca ccatcatctc aaaaaaatat gaaaaaagtt
    32041 tatctcgttt gtgatgaagg tgttgcggtt tcgagacttt tgctgaaaca atgcaaactt
    32101 tattttccaa atgagcaaat tgacactgta tttacaacag aacaatttaa gagtgtggaa
    32161 gatattgcac aagttgatgt agtgattact actaatgatg atttggatag cagatttccg
    32221 attttaaggg ttaatcctat ccttgaagca gaagatattt tgaaaatgct agactatctt
    32281 aaacacaata tatttcgtaa taagagcaaa agtttcagtg aaaatctttc tagtcttatt
    32341 tcgtcttata ttgtagacag caagttggct agtaagttcc aagaagaggt tcaaacactt
    32401 ataaatcaag aaatagtagt tcaagctttt ttggaagata tttgaaggac agtccaatga
    32461 tgaacacaaa cctgtgtttt tcttggtctt ttttagtgtt ttgaagggtg gtatactaat
    32521 ctcaaagata acaattatat ccaaaggagg caacatatgc caaacgtcaa agaaattaca
    32581 agagagtcat ggattttagc cactttccca gagtggggaa catggttgaa cgaagaaatc
    32641 gaagaagaag tcgtacctga aggcaacttt gccatgtggt ggctaggcaa ctgtggtact
    32701 tggattaaga caccagctgg tgctaacgtt gtcatggacc tttggtcaaa ccgtggaaaa
    32761 tcaaccaaaa aagtgaaaga tatggttcgt gggcaccaaa tggcaaatat ggcaggtgtt
    32821 cgtaagctgc aaccaaactt gcgtgttcag ccaatggtta tcgatccatt tgctatcaac
    32881 gaactagact attacttagt ttcacacttc cacagtgatc atatcgaccc atacacagct
    32941 gcagcaattc tcaataatcc taagttagag catgttaagt ttatcggtcc ttaccactgt
    33001 ggacgaatct gggaaggatg gggtgttcca aaagaacgta tcatcgttgt taaaccaggt
    33061 gacactatcg aattaaaaga tatgaagatt catgcagtag aatcatttga ccgtacttgc
    33121 ttggtaactc tcccagtgaa cggtgctgat gagacaggcg gtgaacttgc tggcttggct
    33181 gttacagatg aagaaatggc tcaaaaggct gttaactata tctttgaaac accaggtgga
    33241 accatctatc atggtgcaga ttctcacttc tcaaactatt ttgcaaaaca tggtaaagac
    33301 tttaaaattg atgttgcttt gaataactat ggtgaaaatc cggtaggtat ccaagacaaa
    33361 atgacatcta tcgaccttct tcgtatggca gaaaatctgc gtaccaaagt cattatccca
    33421 gttcactatg atatctggtc taacttcatg gcttctacta atgagattct agaactttgg
    33481 aaaatgcgaa aagatcgctt gcaatacgat ttccatccat ttatctggga agttggcggt
    33541 aagtacactt atcctcaaga tcaacactta gtagaatacc atcatccacg tggttttgat
    33601 gattgttttg aacaagactc taacattcaa tttaaagctt tgctataata taaaaatatt
    33661 ctttggaggt tatccgtatg ttgcatgata cggataattt tcatataata gtaaaataga
    33721 atgtgtgatt caataatcac ctcaaataga aaggaaattc tatgtcaaat ctatctgtta
    33781 atgcaattcg ttttctaggt attgacgcca ttaataaagc caactcaggt catccaggtg
    33841 tggttatggg agcggctccg atggcttaca gcctctttac aaaacaactt catatcaatc
    33901 cagctcaacc aaactggatt aaccgcgacc gctttattct ttcagcaggt catggttcaa
    33961 tgctccttta tgctcttctt cacctttctg gttttgaaga tgtcagcatg gatgagatta
    34021 agagtttccg tcaatggggt tcaaaaacac caggtcaccc agaatttggt catacggcag
    34081 ggattgatgc tacgacaggt cctctagggc aagggatttc aactgctact ggttttgccc
    34141 aagcagaacg tttcttggca gccaaatata accgtgaagg ttacaatatc tttgaccact
    34201 atacttacgt tatctgtgga gacggagact tgatggaagg tgtctcaagc gaggcagctt
    34261 catacgcagg cttgcaaaaa cttgataagt tggttgttct ttatgattca aatgatatca
    34321 acttggatgg tgagacaaag gattccttta cagaaagtgt tcgtgaccgt tacaatgcct
    34381 acggttggca tactgccttg gttgaaaatg gaacagactt ggaagccatc catgctgcta
    34441 tcgaaacagc aaaagcttca ggcaagccat ctttgattga agtgaagacg gttattggat
    34501 acggttctcc aaacaaacaa ggaactaatg ctgtacacgg cgcccctctt ggagcagatg
    34561 aaactgcatc aactcgtcaa gccctcggtt gggactacga accatttgaa attccagaac
    34621 aagtatatgc tgatttcaaa gaacatgttg cagaccgtgg cgcatcagct tatcaagctt
    34681 ggactaaatt agttgcagat tataaagaag ctcatccaga actggctgca gaagtagaag
    34741 ccatcatcga cggacgtgat ccagtcgaag tgactccagc agacttccca gctttagaaa
    34801 atggtttttc tcaagcaact cgtaattcaa gtcaagatgc cttgaatgtt gtggcagcta
    34861 aattaccaac ctttctaggt ggatcagctg accttgctca ctcaaacatg acttatatca
    34921 agacggatgg acttcaagac gatgccaatc gcttgaatcg taacattcag tttggtgttc
    34981 gtgaatttgc aatgggaaca atcttgaacg ggatggccct tcatggtgga cttcgtgtat
    35041 acggtggaac tttcttcgtc ttctctgact atgtgaaggc agctgtccgc ttgtcagcct
    35101 tacaaggact tcctgtgact tatgtcttta cccatgattc aatcgcagtt ggggaagatg
    35161 gtccgactca tgaaccagtt gagcatttag caggtcttcg tgctatgcca aatctaaatg
    35221 ttttccgtcc agcagatgcg cgtgaaacgc aagcagcttg gtaccttgca gtgacaagtg
    35281 agaaaacacc aactgccctt gtcttgacac gtcaaaattt gactgttgaa gatggaacag
    35341 acttcgacaa ggttgctaaa ggtgcttatg ttgtatatga aaatgcagcc gactttgata
    35401 ccatcttgat tgcgacaggt tcagaggtta atcttgctgt ctcagctgct aaagaattgg
    35461 ctagtcaagg cgaaaaaatc cgcgtagtca gcatgccatc tacagatgtc tttgataaac
    35521 aagatgcagc ttacaaggaa gaaattcttc caaatgcagt ccgccgtcgt gttgcagtcg
    35581 aaatgggtgc aagtcaaaac tggtacaaat atgttggtct cgatggtgcc gttctaggta
    35641 ttgatacctt cggagcctct gccccagcac caaaagtatt ggcagaatat ggctttactg
    35701 tagaaaatct tgtaaaagtt gttcgaaact tgaaataatc ctaaaaatca gggcgtaagc
    35761 tctggttttt cttaccagaa aagtaaggta caatcttgta aaagtagctg aaatttgata
    35821 tagtagtcct atgtaaaaga caaaggagaa aacaatgaat ccaaatatta cttttttaat
    35881 catgcttgta ggtatgatgg ccttgatgtt ctttatgcaa cgttctcaaa agaaacaagc
    35941 tcaaaagcgt atggaaagct taaataaact acaaaaaggc tatgaagtga ttacaatcgg
    36001 tggactttat ggaacagtcg atgaagtaga tacggagaag ggaacaatag ttcttgacgt
    36061 agatggagtt tacttgactt ttgaactagc tgctatcaag acagtattac cgctgaaaga
    36121 aacagcttca ctagaaggcg caattgaaaa ataagacggg atcacgaact cccgttttct
    36181 ataaaagaaa ggaaatggga tgaaaaaatt agtctttgtc tgtctgggaa atatttgccg
    36241 tagccctatg gccgagtttg ttatgaaatc aatgacagat aactacgaaa tccaaagtcg
    36301 agcaacttcc tcttgggaac atggcaatcc gattcataag gggactcagg gaatttttca
    36361 agagtatgag attccttatg acaagaacaa gacatcgctt cagattagta aggaagattt
    36421 tgaagccttt gattatatta tcggaatgga cgcttcaaat atttctgact tacgtcagat
    36481 gtgtccagta gactgtcaag ataagattta ctcattttca tctgaaagtg ttccagaccc
    36541 ttggtataca ggagattttg aagaaaccta tcgacgtgtt caagagggct gtcaagcttg
    36601 gttagaacgt ttagaaaagg agagttaagg tggaaaatct tacgaatttt tacgaaaagt
    36661 atcgtgtcta tctgactcgt ccacgtttag agcttttggc agtagttacc attgttttct
    36721 gtgctgtact cgtctttttt ctaaatattc caggaaaagg tgtcttaaaa ctcgataatg
    36781 gaacgattgt ttatgatggc agtcttgtcc gcggtaaaat gaatggccaa ggtaccatta
    36841 ccttccaaaa tggagaccaa tatacaggtg gcttcaacaa tggagccttc aacggaaaag
    36901 gtacctttca atctaaagaa ggctggacct acgaaggtga ttttgtaaat ggtcaggctg
    36961 aaggaaaagg gaaactaaca acagaacaag aagtcgttta tgaaggaact tttaaacaag
    37021 gcgtttttca acaaaaataa agcctcctta tcaaaggagg tattattaga atcgcaaggt
    37081 aagcgcttac ctgcaaatcc ctttctttcc aaatccctct tccaagcaag tttgtgaaat
    37141 aaaaaatatt tgaaataaat ttcacaaact tcaaagataa aacctgataa gaaaagaaaa
    37201 tgagaaaagt ttcacaagag tttaaaaatt ctttgtgaaa tgtttatgaa actgtttaca
    37261 aagttgaaat aatgcgttat aataaacttg tgaaaaaatt aacaaaggat atcgttcctt
    37321 gaaagctatg gaggaaaata tggctgataa aaaaactgtg acaccagagg aaaagaaact
    37381 cgttgctgaa aaacacgtag atgagttggt tcaaaaagct ctagttgccc ttgaagaaat
    37441 gcgtaaattg gatcaagaac aagttgacta catcgttgcc aaagcatcag tagcagcttt
    37501 ggatgcccac ggagaattgg ctttacatgc ctttgaagaa acaggacgtg gtgtatttga
    37561 agacaaagca actaagaact tgtttgcctg tgaacacgta gtaaacaaca tgcgccacac
    37621 taagacagtt ggcgttatcg aagaagacga tgtaacagga ttgactctta ttgctgaacc
    37681 agttggtgtt gtttgtggta ttactccaac aacaaaccca acatcaacag caatcttcaa
    37741 atcattgatt tcattgaaga cacgtaaccc aatcgtcttt gccttccatc catcagcaca
    37801 agaatcatct gctcatgcag ctcgtatcgt ccgcgatgca gctatcgcag ctggtgctcc
    37861 tgaaaactgt gtgcaatgga ttactcaacc atctatggaa gcaacaagtg cccttatgaa
    37921 ccacgaaggt gttgcgacaa tccttgcaac aggtggtaat gccatggtta aggcggctta
    37981 ttcatgtggt aaaccagctc ttggggtagg tgccggaaac gttccagctt atgttgaaaa
    38041 atcagcaaac attcgtcaag cagcacacga tatcgtcatg tctaaatcat ttgataacgg
    38101 tatggtctgt gcatctgaac aagcagttat cattgataaa gaaatttacg atgaatttgt
    38161 agcagagttc aaatcttacc acacttactt tgtaaacaaa aaagaaaaag ctcttcttga
    38221 agagttctgc ttcggcgtca aagcaaacag caaaaactgt gctggtgcaa aattgaacgc
    38281 tgacatcgtt ggtaaaccag caacttggat tgcagaacaa gcaggattta cagttccaga
    38341 aggaacaaac attcttgctg cagaatgtaa agaagttggc gaaaatgagc cattgactcg
    38401 tgaaaaattg tcaccagtta ttgcagtttt gaaatctgaa agccgtgaag atggtattac
    38461 taaggctcgt caaatggttg aatttaacgg tcttggacac tcagcagcta tccacacagc
    38521 tgacgaagaa ttgactaaag aatttggtaa agctgttaaa gctattcgtg ttatctgtaa
    38581 ctcaccttct acttttggtg gtatcgggga cgtttacaat gccttcttgc catcattgac
    38641 acttggatgt ggttcttacg gacgcaactc agttggggat aacgttagtg ccattaacct
    38701 cttgaatatc aaaaaagtcg gaagacggag aaataacatg caatggatga aacttccttc
    38761 aaaaacatac tttgaacgtg attcaattca ataccttcaa aaatgtcgtg acgttgaacg
    38821 tgtcatgatc gttactgacc atgccatggt agagcttggt ttccttgatc gtatcatcga
    38881 acaactggac cttcgtcgca ataaggttgt ttaccaaatc tttgcggatg tagaaccgga
    38941 tccagatatc acaactgtaa accgtggtac tgagattatg cgtgccttca aaccagatac
    39001 catcatcgca ctcggtggtg ggtctccaat ggatgctgcc aaagtaatgt ggctcttcta
    39061 cgagcaacca gaagtggact tccgtgacct tgtccaaaaa ttcatggata tccgtaaacg
    39121 tgccttcaag ttcccattgc ttggtaagaa gactaaattc atcgcgattc caactacatc
    39181 tggtacagga tctgaagtaa caccatttgc cgttatctct gataaagcaa acaaccgtaa
    39241 atacccaatc gctgactact cattgacacc aactgtggca atcgtagatc ctgctttggt
    39301 attgacagtt ccaggatttg ttgctgctga tactggtatg gacgtattga ctcacgcgac
    39361 agaagcatac gtatcacaaa tggctagtga ctacactgat ggtttagcac ttcaagccat
    39421 taaattggtc tttgaaaatc tcgaaagctc agttaagaat gcagacttcc actcacgtga
    39481 gaaaatgcat aacgcttcaa caatcgctgg tatggccttt gccaatgcct tcctaggtat
    39541 ttctcactca atggcccata agattggtgc gcaattccac acaatccacg gtcgtacaaa
    39601 tgctatcttg cttccatacg ttatccgtta caacggtaca cgtccagcta agacagcaac
    39661 atggcctaag tacaactact accgtgcaga tgaaaaatac caagatatcg cacgcatgct
    39721 tggacttcca gcttctactc cagaagaagg ggttgaatct tacgcaaaag ctgtctacga
    39781 actcggtgaa cgtattggga tccaaatgaa ttttagagac caaggaattg acgaaaaaga
    39841 atggaaagaa cattctcgta aattagcctt cctggcttat gaagaccaat gttcaccagc
    39901 taacccacgt cttccaatgg tagaccatat gcaagaaatc atcgaagatg catactatgg
    39961 ctacaaagaa agaccaggac gccgtaaata attgtttatc agtctagaag caagacaaaa
    40021 actcaatttg agggaaagat ccagtaattt ttctatgata aaaggcatcc tatcaaggtt
    40081 tttgaacacc tgataggatg cctttttatg atattgaggc ctttttgccc tttttgaaaa
    40141 actagaatag aaacaaaata tataatagat tgaaactaga atagtacata tctgcttcta
    40201 aaacattgtt agaattcgat ttgactgtcc tgatcgattt gtcctgttct tatttcattt
    40261 tgatatataa aaaatatagt atagtagact gaatctaaaa tagtacgaaa caattgctaa
    40321 aacatttata gaaattaatt ttacttttct gatagagttg ttcacatctt atttcaattc
    40381 actatagttt aatttaagag tagtatttac taaggcccaa ttaaaatcaa agagcaaact
    40441 agaaaacgag tgccattcag ctcaaaacac tgatttgaga ttgcagataa gactagcccc
    40501 ctcattaaca gatttacgat aaaacgatga caaggtgtgt tgctttttga tttctaaaga
    40561 gtataatgat agatctctat aaaataagtg cgaaggaaat gagcttttat agtcctttcg
    40621 ttttaaaata ctatctcaga tattcttata tcgacaagaa gtttttgagt cattccctca
    40681 tcatacatat taaataaata gtggctcatt caatttttca ctagaataat aagctagtat
    40741 agtaaactga aataagatat aaacaaataa attggagctt aacatccatt tccagcaatt
    40801 ttttagaaac tacagtggac tattctagat tcaacatatt ataaaaacta gagtaaaaga
    40861 aaaggattgg atcttgtgta atgcaggatc caatcctttc aatcattttg tccaactttt
    40921 ggaggttcct acaatgtagt cgtcattaat aaagacagat gggaatgaca gtgttcctat
    40981 ttattttgat agagatcgat gaattcttta gatagcaact gaataatctc tgttgaagcc
    41041 atttggtctt ctgcatgcat aaatagcaag gagaatccta ttttttctcc agtagcttct
    41101 ttttgtatga gattagagtg aatcttgtgc gcttctacta aggagtcttc cgcttcttca
    41161 actttaattt tcgcttcttt taaatttcct gccttagcta gttggatggc ttcaataaag
    41221 gatgatttgg ctgctccact attggcaatg agctgaaaac agatatattc catttcttct
    41281 gtcatcttat ttctcctatc catgcaagtg cttgttccag aacttttgct ccattcatca
    41341 ttccgtaatc ccgcatatca atggtatcta cagggatatt tcctgcaatt tctttcacag
    41401 caagtaactc ataacgaatt tgtggcccaa ttagaatgac atctgcttca tggatattct
    41461 ttttagcttc tgtcattgat tttgcttgga tagagatttc aatcccacgt tcagtcgcac
    41521 tttgttgcat ttttttaaca agcatacttg tcgacattcc cgcattacat actaataaaa
    41581 tttgtttcat aatcttaacc ttccatttct tgttcaacaa ctttgtcatt aactttgata
    41641 aatggaatgt atagaagaac tccaagtgca aagatgatga attgaactag aactgctctc
    41701 acgtcccctg ctgttgctaa ccatgcattt aagaatactg gtgtagtcca aggaacttgt
    41761 ataaatgcag gactcatgaa ttctgtaact gttgctaagt agctgattaa aataccaagg
    41821 actggaactg tgataaatgg aatagctaat gaaatgttat aaacgattgg gtaaccgaat
    41881 aatactggtt cattgatatt gaagatacca ggtccaaaag ataatttagc cacgttttta
    41941 gagacagcat tgcgactcac taagaatgtt gctattaata aacataatgt agatccacta
    42001 ccacccatta aagcgaatgt ttgtatttgt gataggttga tgatgtgtgg aatggcttgt
    42061 ccattatttg ctgcagtgat gttttcagta atgttaatta atagtaatgg ttctaggatg
    42121 gcactgtaaa taactgcttg gtgaatacca aatagccata acatatttcc taaagagtaa
    42181 ataataatga ccccgattaa gcttgtacca atatgacgaa ttggttcttg aataaagatt
    42241 gtaatgattg agattaagtt cattccagtt atattgaata ataatgctga aacaacccca
    42301 aataaggaga tgacggtcat gactggaagt aatacgctaa atgatctact aacagctggt
    42361 ggaatatttt caccaaggtt catttgtaaa gctttaacgt ttgataattc aatgaataat
    42421 tctgttgcaa taatcgctac gataaccccg gcgaacattg cgcctgtacc tgtgttgttg
    42481 aatgaaagaa cacctgaaat gtttaccgca tcttttgctc cgtcaggaac tacagaaact
    42541 gtatttggca tcatcacaat taaagaaact aatgatagca ttgatgctgc taacgggttt
    42601 tcgaaatctc tgtttttagc taagaaataa ccaaccatta cagcaataat catacctgaa
    42661 atacttaaag taccgtttgc aattgttatt ccccaatatt ggaatcttgt taatgtatcc
    42721 ccttggaaaa tccacttaaa taccgtgttg ttcaaaagaa cgattaaacc tgccaaaata
    42781 tataatggca ttactgttac gaatgcatct cttagggttt ttaaatgaat ttggttccct
    42841 agtttaccag caaaggtggc aaattggtct ataaattttg agtttttcat atgaatatct
    42901 cctctcttta ctcctcaatt tctacttcaa aaccgttatt gtcacttact ttgcgatacc
    42961 atcttcctga gctcttgatg gttctctttt gcgtttctaa atcaacggag ataaatccgt
    43021 aacgattctt atatgcatta ttccaagacc agcaatcaaa tgcggtccaa gcgtggtatc
    43081 caaaacagtg acttccctct tcaatggctt tatgtagcca tcttaaatgt tcttcataaa
    43141 attcaatacg atacacgtca tcgataactc cattttcatc gataaaccgt gcttcgtttt
    43201 caacacccat tccgttttca ctgataaacc atgggatatt accatattct tccttcacaa
    43261 tcatagcaat atcataaatg gctttcggaa aaatttccca accacgatat ggattcatgc
    43321 gacgctccag ccattcatac tctttgaagt attggtctgg catccagggc gtctgatatt
    43381 cctcaggatt tgcttgtgct tgaacacgtt ttggatggta gtagtttact ccaagaaaat
    43441 caaccgtatt tgatttcatc agttgaagct ctttttcggt atgactccat aacacgccat
    43501 ctctctctag ctgttttacc aatctttctg ggaaagttcc tttaacagct ggattcaaga
    43561 agactttgtt aaagaagtca tctgtaaatc gacttgcttc taagtcttct ggagaattac
    43621 ttcttggata agcaggtgtc aagtttaaaa taatcccaat ctttccatca agttctaatg
    43681 agcgatatag ttgaatcact tttgcactag caaggtttag attatagatg acttgtacgg
    43741 cctcttttcc ctttcctttt agatttggat aatggaaagc atataagtat cctgcttctg
    43801 gaatgaccat tggctcattg aaagttgtcc agtaatgaac cttatctcca aagcatgtga
    43861 aagcagtctt ggcaaacttc acgaataact ccactacatg tttgctttcc caaccaccgt
    43921 atttttgaag aagttccact ggtaaatcaa aatgatgtaa attcatcaca agatccatct
    43981 ggttcttttt agcttcttca atgatggcat tgtagaaagc aatacctttt ggatcaggct
    44041 cacctgtctc taaattcttg atgagtcgac tccattggat ggaagtgcgg aaagaattaa
    44101 ctccaatttc cttcatcaag tggaaatctt cggtgtaagt atgaaaaaag ttactggcta
    44161 caagaggtcc gacattatcg aaaaaatctt ctggatgcgt tttgaaccag tagtccatca
    44221 cattttcatg tacttttcca tattgacctt ctgtctgagg tccgctagaa gcagctcccc
    44281 accaaaacag attaggaaat actaactttt ttttcatgct caacctcctt tctattattc
    44341 tatacataaa gtatagcata attttaaaat ttgtctagac atttttaaaa attgttgata
    44401 catatcttgt gtttgcctca tttcttgaac tttgttatac tactattaga atattataga
    44461 gagaaccaga ttaaatgagt acaaaatatt tatttattta caatgagatt cgtgaaaaga
    44521 ttctttgtaa taaatatacc atgaacgaac aattgcctga tgaaatgaca ttagctaaac
    44581 agtttgcctg tagtcgaatg acgatcaaaa aagctttaga cttgttagtt tctgagggct
    44641 taatttttag aaaacgtggg cagggaacct ttgttctctc tcgtggcagc tcaaaaagaa
    44701 aattaatcgt tccagaaaga gatatccggg gactgacaaa aatatctgaa gatgctcatt
    44761 ctacaattga ctcgaggatt attcacttca aattagaatt tgcaaatgaa tttttagcag
    44821 aaaaactaca ggtcgctttg cagagtccag tttataatat ttaccgcctg cgtattattg
    44881 acggtaaacc ttatgttctg gaacaaactt atatgagtac cgatgttatt ccaggtatta
    44941 ctgaagatat tttacaaaaa tcgatttaca attacattga aggaaagtta ggattgcata
    45001 ttgccagtgc tacaaaaatc ttacgagctt cttctagttc agaaaatgag caacattact
    45061 tgcagctcct tccaacggaa ccggtatttg aagtagaaca agtggcttat ttggataacg
    45121 gaactccgtt tgagtactcg attagtcgtc atcgctatga tttatttgaa tttaattctt
    45181 ttgcattacg acattcctcc taggagaaaa tgtgaaaatg aagccaatct tttacagact
    45241 ctagtttaag aaaaatttaa aacagggcaa gaaggtccca tctatgctta aatggtttct
    45301 cttttctaaa taagatggct ttaaaagagt gatcgttgta tccatcatgt tgaaaaatat
    45361 cttcgtatag cttatagagt aggtactgaa attgttcacc tgatctactt cttatagtta
    45421 tttagtttta aatagtgttt caaacattct tacactgacg agaagttttt gagtcttttc
    45481 ttgtaacaca tatagtatac tgtggttaga atagtagact gtgacttcta acaaattgct
    45541 agaaatgaat ttcaatctcc caatttattt gttcatatct tcttttaata tattaaataa
    45601 attctaaatc ataatcattt aaaaaaattt tattttttat ttttcattac gaataatata
    45661 gatgaagggg aaagagtatg aaaacagaac tgtttctttt gctattagtt caaaaggaga
    45721 aaaaatgaaa gtagaaaata tttcgtatag ggtggatcat cgtaaattgt ttgataatat
    45781 ttcttttgat acttcgagtt cagacgtgac attaattact ggtaaaaatg gtacaggaaa
    45841 gtcaacttta ctatagtaga ttgaaactag aatagtacac atctacttct aaaatattgt
    45901 tagaaatcga tttgactatc ctgatctatt tgtcctgttc ttatttcatt tcactatatc
    45961 tcaaattgag tatgacgaag tgcgctccca tgtcctggga acgcactttc ttcatatttt
    46021 tcatattctt gaatccatcg ataaagacta ttgggatgaa tttttaaagt tgaactaatc
    46081 atttttacag gatgagattt acagcagaga gtttgaaggc tttatcaaag gtttttcttg
    46141 gcataatgac ttttcctcgt ttccacttaa ttttgtgtct actttattat accaagtcca
    46201 cccttaagtt agataataaa tctaacttaa ggaagctaga aggatgagaa tccaggtggt
    46261 caagagtccc aaacttaagc tgatggggac acccagaata atttgctttt tgaaggcaag
    46321 gccacgttcc tctatattgg gaagtgagag ttgaatgaga gaaccagctg atgaaaaggg
    46381 tgagatatta gtagatagag cgccaataac ggtggctgtt gtgagtaagt gaatatcaat
    46441 ctgaggattt tgagcactga tgatagcaat gatgggaaag agggctggag ctacaacgga
    46501 tagggtggaa ctaaagagtg acatcactcc ggctatcaca caaaagaaca gaggtaacca
    46561 gaaatgagga atggttgttg tcatgaggtg ccctatcagt gtgactaaac ctgacttgac
    46621 cgctagagac attagtaagc tcatgccgca gagcatgata attgtagccc agggaacctt
    46681 agctaaaatg gcttcttgct tccctaattt gagccttaag gcgaggcaga ccatgagtat
    46741 tgagacaaag ccaatatcaa atgttttttg ataagtagct atccaggcga tgtttgggaa
    46801 aatgagatgc aacaagggaa aaagccaaac caaaaccatg ctgctgatca tgagcaaggt
    46861 ggtttgtctt tgaaccttgc tgaggagtgg tggttggtca atagtcaagg atgagtttgt
    46921 tcttccctta ctatagtgac tgtaacagga taataaaagc aagacgatga gtgggtagat
    46981 aatgctgacg ataaagatat gattgccaag tgaaaaagct tgctcttccc atcccatttg
    47041 cttaaacagg ccttgaaaga caatgcctga gctactggtt atcaaattag cccctcctga
    47101 agctccccaa ttgacggctt gagctccaat caaagggtgt ttgtccgctt tttgacagag
    47161 ggtaatcgct agaggacagc aaacggccat agtagtgaaa aatccagcac ctaaagcaga
    47221 caaaagggtt gccatcaggt ataaaatcat gtagagggcg ttagggtggg tgcgtgtgcg
    47281 gtagagaatg tgttgagcca aaacatcaag agtaccgtta gttgttgcaa cgttataaaa
    47341 gagagagacg ctaaaaatgg taaaaaagag tgaggttggc caaaaatgaa gaagttcttt
    47401 ggggcttaat cccatgagag tggttgcgat gaggtaagaa aaagcaatag ccagcaggcc
    47461 aatattgatt ttggtgcggt aaccaattcc aatggctaga gcaatggcgc taatcattat
    47521 taaatgaatc attgaattgt cctttcagtt agaatatgga aataggttgg caattttggc
    47581 gctcaaaaga ccacctgttt cctattggta cttgactatt atacacaaaa aaaatacaat
    47641 tgtcttgaca attgtcttga cacttgttag aattaaaaat gaggtattca ggcttgtgat
    47701 ttcctatgga agttaatagt gattgcctct aatgcttaca agtgatatta aaaatagagg
    47761 acctagtgat gtcaatcatt tcaactgatt taaccccttt tcaaatagat gatacattga
    47821 aagcagcctt gcgagaagat gttcattccg aagattacag taccaatgcc atttttgatc
    47881 atcatggcca agccaaggtg tcgctttttg ccaaggaagc tggtgtttta gcggggctaa
    47941 ccgtttttca aagggttttt accctatttg atgccgaggt gaccttccag aatcctcatc
    48001 aatttaagga tggggatcgt ttgactagtg gcgatttggt tttagaaatc ataggctcgg
    48061 tgagaagtct cttaacatgt gaacgcgttg ccttgaattt tttacaacat ttatcaggga
    48121 ttgcttcgat gacagctgct tatgtagaag ccttaggcga tgattgcatt aaggtatttg
    48181 atactcgaaa aactactcct aatttacgtc tttttgagaa atatgccgtg agagttggcg
    48241 gtggctataa tcatcgcttt aatttatcag atgctatcct gctaaaagac aatcacattg
    48301 cggcagtagg tagtgttcaa aaggcaattg ctcaagcgcg tgcctatgcc ccttttgtga
    48361 aaatggtcga ggtggaagtg gaaagccttg ctgctgccga agaagctgcg gcggcgggtg
    48421 ctgatattat catgttggat aatatgtcat tggaacagat tgaacaggcc attaccctaa
    48481 ttgcaggacg ttctcggatt gaatgttctg gaaatattga tatgaccact attagccgtt
    48541 ttcgtggttt agcgattgat tacgtctcca gtggtagttt aacccatagt gctaagagtc
    48601 ttgatttttc catgaagggg ttaacctacc ttgatgtcta agttgtaaaa taaactaact
    48661 ttttaaagga tgtctttcct ctagaacgag ttttatgtca gatagtttaa acgcctcttc
    48721 aaatatagta aaatgaacca aaaatagtac acaatgtggt ataatctttt tatggcatat
    48781 tcaatagatt ttcgtaaaaa agttctctct t
//
LOCUS       DAVFER010000014        47180 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1105170250
            SAMEA2167659-rid19724873.denovo.014, whole genome shotgun sequence.
ACCESSION   DAVFER010000014 DAVFER010000000
VERSION     DAVFER010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2167659
            Sequence Read Archive: ERR388902
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 47180)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 47180)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928716.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928716.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 04:07:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,118
            CDSs (total)                      :: 2,073
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 120
            CDSs (without protein)            :: 120
            Pseudo Genes (ambiguous residues) :: 0 of 120
            Pseudo Genes (frameshifted)       :: 67 of 120
            Pseudo Genes (incomplete)         :: 47 of 120
            Pseudo Genes (internal stop)      :: 34 of 120
            Pseudo Genes (multiple problems)  :: 23 of 120
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..47180
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2167659-rid19724873.denovo.014"
                     /strain="1105170250"
                     /db_xref="taxon:1313"
     gene            <1..209
                     /locus_tag="VU534_000803"
     CDS             <1..209
                     /locus_tag="VU534_000803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU1513416.1"
                     /translation="RKSSKLKPLTAEDKAYNHALSKERSKVENIFAKVKTFKMFSTTY
                     RNHRKRFGLRMNLIAGIINHELGF"
     gene            complement(261..623)
                     /locus_tag="VU534_000804"
     CDS             complement(261..623)
                     /locus_tag="VU534_000804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000604884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1513417.1"
                     /translation="MPKTKTLAELADVILWSFDFANDHAHAFFMDNVEWSHADSYFRS
                     FVSDDVEERYTENVYLDSLSVKQKFKFIFDFGDEWRFECQVLREIETEDEEAYLVRSV
                     GTSPEQYPDYDGFDYEEW"
     gene            complement(624..833)
                     /locus_tag="VU534_000805"
     CDS             complement(624..833)
                     /locus_tag="VU534_000805"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1513418.1"
                     /translation="MKQKNYLVSNATVRQTYDKIAESECFLRAIGGIMLHLKLVKQEI
                     EAEKPASVEAWIISVKFKKGCYRHI"
     gene            complement(985..2865)
                     /locus_tag="VU534_000806"
     CDS             complement(985..2865)
                     /locus_tag="VU534_000806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 20 glycosylhydrolase"
                     /protein_id="HEU1513419.1"
                     /translation="MVRFTGLSLKQTQAIEVLKGHISLPDVEVAVTQSDQASISIEGE
                     EGHYQLTYRKPHQLYRALSLLVTVLAEADKVEIEEQAAYEDLAYMVDCSRNAVLNVAS
                     AKQMIEILALMGYSTFEIYMEDTYQIEGQPYFGYFRGAYSAEELQEIEAYAQQFDVTF
                     VPCIQTLAHLSAFVKWGVKEVQELRDVEDILLIGEEKVYDLIDGMFATLSKLKTRKVN
                     IGMDEAHLVGLGRYLILNGVVDRSLLMCQHLERVLDIADKYGFHCQMWSDMFFKLMSA
                     DGQYDRDVEIPEETRVYLDRLKDRVTLVYWDYYQDSEEKYNRNFRNHHKISHDLAFAG
                     GAWKWIGFTPHNHFSRLVAIEANKACRANQIKEVIVTGWGDNGGETAQFSILPSLQIW
                     AELSYRNDLDGLSAHFKTNTGLTVEDFMQIDLANLLPDLPGNLSGINPNRYVFYQDIL
                     CPILDQHMTPEQDKPHFAQAAETLANIKEKAGNYAYLFETQAQLNAILSSKVDVGRRI
                     RQAYQADDKESLQQIARQELPELRSQIEDFHALFSHQWLKENKVFGLDTVDIRMGGLL
                     QRIKRAESRIEVYLAGQLDRIDELEVEILPFTDFYADKDFAATTANQWHTIATASTIY
                     TT"
     gene            complement(2859..3728)
                     /locus_tag="VU534_000807"
     CDS             complement(2859..3728)
                     /locus_tag="VU534_000807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEU1513420.1"
                     /translation="MTIATIDIGGTGIKFASLTPDGKILDKTSISTPENLEDLLAWLD
                     QRLSEQDYSGIAMSVPGAVNQETGVIDGFSAVPYIHGFSWYEALSSYQLPVHLENDAN
                     CVGLSELLAHPELENAACVVIGTGIGGAMIINGRLHRGRHGLGGEFGYMTTLAPAEKL
                     NNWSQLASTGNMVRYVIEKSGHTDWDGRKIYQEAAAGNILCQEAIERMNRNLAQGLLN
                     IQYLIDPGVISLGGSISQNPDFIQGVKKAVEDFVDAYEEYTVAPVIQACTYHADANLY
                     GALVNWLQEEKQW"
     gene            complement(3811..6456)
                     /locus_tag="VU534_000808"
     CDS             complement(3811..6456)
                     /locus_tag="VU534_000808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000432759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HEU1513421.1"
                     /translation="MENVVVHIISHSHWDREWYLPFESHRMQLVELFDNLFDLFENDP
                     EFKSFHLDGQTIVLDDYLQIRPENRDKVQRYIDEGKLKIGPFYILQDDYLISSEANVR
                     NTLIGQQEAAKWGKSTQIGYFPDTFGNMGQAPQILQKSGIHVAAFGRGVKPIGFDNQV
                     LEDEQFTSQFSEMYWQGVDGSRVLGILFANWYSNGNEIPVDKDEALTFWKQKLSDVRA
                     YASTNQWLMMNGCDHQPVQKNLSEAIRVANELFPDVIFVHSSFDEYVQAVEGALPEHL
                     STVTGELTSQETDGWYTLANTSSSRIYLKQAFQENSNLLEQVVEPLTIITGGHNHKDQ
                     LTYAWKTLLQNAPHDSICGCSVDEVHREMETRFAKVNQVGNFVKSNLLNEWKGKIATD
                     KAQSDYLFTVINTGLHDKVDTVSTVIDVATCDFKELHPTEGYKKMAALILPSYRVEDL
                     DGRPVEATIEDLGANFEYNLPKDKFRQARIARQVRVTIPVHLAPLSWTTFQLLEGKQE
                     HREGIYQNGVIDTPFVTVSVDDNITVYDKTTHEAYEDFIRFEDRGDIGNEYIYFQPKG
                     TEPIFAELKGHEVLENTACYAKILLKHELTVPVSADEKLEEEQQGIIEFMKREAGRSE
                     ELTNIPLETELTVFVDNPQIRFKTRFTNTAKDHRIRLLVKTHNTRPSNDSESIYEVVT
                     RPNKPAASWENPENPQHQQAFVSLYDDEKGVTVSNKGLNEYEILGDNTIAVTILRASG
                     ELGDWGYFPTPEAQCLREFEVEFALECHQAQERFSAYRRAKALQTPFTSLQLARQEGS
                     VVATGSLLSHSVLSIPQVCPTAFKVAENEEGYVLRYYNMCSENVRVPESQHLFLDLLE
                     RPYPVHSGLLAPQEIRTEFIKKEEI"
     gene            complement(6547..7827)
                     /locus_tag="VU534_000809"
     CDS             complement(6547..7827)
                     /locus_tag="VU534_000809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
                     /protein_id="HEU1513422.1"
                     /translation="MVYSKEIVREWLDEVAERAKDYPEWVDVFERCYTDTLDNTVEIL
                     EDGSTFVLTGDIPAMWLRDSTAQLRPYLHVAKRDALLRQTIAGLVKRQMTLVLKDPYA
                     NSFNIEENWKGHHETDHTDLNGWIWERKYEVDSLCYPLQLAYLLWKETGETSQFDEIF
                     VAATKEILHLWTVEQDHKNSPYRFVRDTDRKEDTLVNDGFGPDFAVTGMTWSAFRPSD
                     DCCQYSYLIPSNMFAVVVLGYVQEIFAALNLADSQSVIADAKRLQDEIQEGIKNYAYT
                     TNSKGEKIYAFEVDGLGNASIMDDPNVPSLLAAPYLGYCSVDDEVYQATRRTILSSEN
                     PYFYQGEYASGLGSSHTFYRYIWPIALSIQGLTTRDKAEKKFLLDQLVACDGGTGVMH
                     ESFHVDDPTLYSREWFSWANMMFCELVLDYLDIR"
     gene            7999..10083
                     /locus_tag="VU534_000810"
     CDS             7999..10083
                     /locus_tag="VU534_000810"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000803403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GH92 family glycosyl hydrolase"
                     /protein_id="HEU1513423.1"
                     /translation="MKPLLETIDTRFGTTNKHAFSRGNTLPYTGVPFGMNYFVPQTSD
                     QDGSWFFDPHLPIFQGIRLTHQPSPWIGDYSWLLLTPVTSQLGGDSLFHRQSSYDIDK
                     ACFQPHYLKLFSLRYQIETQLTPTCYGASIRLNQKQGKALSLYLHAADELTVEQVDKR
                     TLALRQEGKTETNKNSLTMFTALQMNTDILAISQEAGDWRIDLASSQTEMQLATSFIS
                     PSQALINLPQEDFDSCKSSAQVDWENLLHRFDIIETGEADRTFFDHCLYRLFLFPQTF
                     YEINESGQAIHMDLATGTVKPGVLFSNNGFWDTFRTTFPLFALIIPEHYQRFLEGFLN
                     SYRDTGFLPKWLAPDERGMMPGTLLDGIIADSACKDMTPDLEGELFQAMLETASKADP
                     LGINGRHGLAQYQELGYLSTDHHESVSHTLDYAYSDFCIASCAKKLENIEIAETYKAA
                     SQNYRQLFDAETGYMRARDNQGNFHPDFSPYSWGRDYAECSAIQATLGVLHDIPGLIQ
                     LMGGKETFSNYLLKACQDAPLFETTGYGYEIHEMSEMATAPFGQIAISNQPSFHIPYL
                     FRYSDYPDYTALLIKTLRQKAFHPSWEAYPGDEDNGSLSAWYIWSALGFYPTCPGKPS
                     YDLGIPLFDHLRVYLAKEDKWLDIHTKQNHNHFNFVKECRLDKTLVSTIQHQDLLKAE
                     QLTFTLSWLPSH"
     gene            complement(10123..11802)
                     /locus_tag="VU534_000811"
     CDS             complement(10123..11802)
                     /locus_tag="VU534_000811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000721501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-L-fucosidase"
                     /protein_id="HEU1513424.1"
                     /translation="MKKIKPHGPLPSQTQLAYLGDELAAFIHFGPNTFYDQEWGTGQE
                     DPERFNPSQLDAREWVRVLKETGFKKLILVVKHHDGFVLYPTAHTDYSVKVSPWRRGK
                     GDLLLEVSQAATEFDMDMGVYLSPWDAHSPLYHVDREADYNAYYLAQLKEILSNPNYG
                     NAGKFAEVWMDGARGEGAQKVNYEFEKWFETIRDLQGDCLIFSTEGTSIRWIGNERGY
                     AGDPLWQKVNPDKLGTEAELNYLQHGDPSGTIFSIGEADVSIRPGWFYHEDQDPKSLE
                     ELVEIYFHSVGRGTPLLLNIPPNQAGLFDAKDIERLYEFATYRNELYKEDLALGAEVS
                     GPALSADFACRHLTDGLETSSWASDADLPIQLELDLGSPKTFDVIELREDLKLGQRIA
                     AFHVQVEVDGVWQEFGSGHTVGYKRLLRGAVVEAQKIRVVITESQALPLLTKISLYKT
                     PGLSKKEVVQELAFAEKSLAVAKGENAYFTVKRRECSGPLEAKISIQPGTGVHGVAYQ
                     DEIQVLAFQTGETEKSLTLPTLYFAGDKTLDFYLNLTVDGQLVDQLQVQVS"
     gene            12557..13786
                     /gene="arcA"
                     /locus_tag="VU534_000812"
     CDS             12557..13786
                     /gene="arcA"
                     /locus_tag="VU534_000812"
                     /EC_number="3.5.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000094613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
                     /protein_id="HEU1513425.1"
                     /translation="MSSHPIQVFSEIGKLKKVMLHRPGKELENLLPDYLERLLFDDIP
                     FLEDAQKEHDAFAQALRDEGIEVLYLEQLAAESLTSPEIRDQFIEEYLDEANIRDRQT
                     KVAIRELLHGIKDNQELVEKTMAGIQKVELPEIPDEAKDLTDLVESEYPFAIDPMPNL
                     YFTRDPFATIGNAVSLNHMFADTRNRETLYGKYIFKYHPIYGGKVDLVYNREEDTRIE
                     GGDELVLSKDVLAVGISQRTDAASIEKLLVNIFKKNVGFKKVLAFEFANNRKFMHLDT
                     VFTMVDYDKFTIHPEIEGDLHVYSVTYENEKLKIVEEKGDLAELLAQNLGVEKVHLIR
                     CGGGNIVAAAREQWNDGSNTLTIAPGVVVVYDRNTVTNKILEEYGLRLIKIRGSELVR
                     GRGGPRCMSMPFEREEV"
     gene            13844..14860
                     /gene="argF"
                     /locus_tag="VU534_000813"
     CDS             13844..14860
                     /gene="argF"
                     /locus_tag="VU534_000813"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003073325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HEU1513426.1"
                     /translation="MTNSVFQGRSFLAEKDFTRAELEYLIGLSAHLKDLKKRNIQHHY
                     LAGKNIALLFEKTSTRTRAAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRM
                     FDGIEFRGFSQRMVEELAEFSGVPVWNGLTDEWHPTQMLADYLTVQENFGRLEGLTLV
                     YCGDGRNNVANSLLVTGAILGVNVHIFSPKELFPEKEIVELAEGFAKESGAHVLITED
                     ADEAVKDADVLYTDVWVSMGEEDKFAERVALLKPYQVNMDLVKKAGNENLIFLHCLPA
                     FHDTHTVYGKDVAEKFGVEEMEVTDEVFRSKYARHFDQAENRMHTIKAVMAATLGNLY
                     IPKV"
     gene            15025..15972
                     /gene="arcC"
                     /locus_tag="VU534_000814"
     CDS             15025..15972
                     /gene="arcC"
                     /locus_tag="VU534_000814"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003025409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HEU1513427.1"
                     /translation="MANRKIVVALGGNAILSSDPSAKAQQEALVETAKHLVKLIKNGD
                     DLIITHGNGPQVGNLLLQHLASDSEKNPAFPLDSLVAMTEGSIGFWLKNALQNALLDE
                     GIEKNVASVVTQVVVDKNDPAFVNLSKPIGPFYSEEEAKAEAEKSGATFKEDAGRGWR
                     KVVASPKPVDIKEIETIRTLLNNGQVVVAAGGGGIPVVKENNGHLTGVEAVIDKDFAS
                     QRLAELVDADLFIVLTGVDYVFVNYNKPNQEKLEHVNVAQLEEYIKQDQFAPGSMLPK
                     VEAAIAFVNGRPEGKAVITSLENLGALIESESGTIIEKG"
     gene            16181..17692
                     /locus_tag="VU534_000815"
     CDS             16181..17692
                     /locus_tag="VU534_000815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004191872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HEU1513428.1"
                     /translation="MSEKAKKGFKMPSSYTVLLIIIAIMAVLTWFIPAGAFIEGIYET
                     QPQNPQGIWDVLMAPIRAMLGTHPEEGSLIKETSAAIDVAFFILMVGGFLGIVNKTGA
                     LDVGIASIVKKYKGREKMLILVLMPLFALGGTTYGMGEETMAFYPLLVPVMMAVGFDS
                     LTGVAIILLGSQIGCLASTLNPFATGIASATAGVGTGDGIVLRLIFWVTLTALSTWFV
                     YRYADKIQKDPTKSLVYSTRKEDLKHFNVEESSSVESTLSSKQKSVLFLFVLTFILMV
                     LSFIPWTDLGVTIFDDFNTWLTGLPVIGNIVGSSTSALGTWYFPEGAMLFAFMGILIG
                     VIYGLKEDKIISSFMNGAADLLSVALIVAIARGIQVIMNDGMITDTILNWGKEGLSGL
                     SSQVFIVVTYIFYLPMSFLIPSSSGLASATMGIMAPLGEFVNVRPSLIITAYQSASGV
                     LNLIAPTSGIVMGALALGRINIGTWWKFMGKLVVAIIVVTIALLLLGTFLPFL"
     gene            17714..19045
                     /locus_tag="VU534_000816"
     CDS             17714..19045
                     /locus_tag="VU534_000816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000686986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase"
                     /protein_id="HEU1513429.1"
                     /translation="MKIDITNQVKDEFLISLKTLISYPSVLNEGENGTPFGQAIQDVL
                     EKTLEICRDIGFTTYLDPKGYYGYAEIGQGAELLAILCHLDVVPSGDEADWQTPPFEA
                     TIKDGWVFGRGVQDDKGPSLAALYAVKSLLDQGIQFKKRVRFIFGTDEETLWRCMARY
                     NTIEEQASMGFAPDSSFPLTYAEKGLLQVKLHGPGSDQLELEVGGAFNVVPDKANYQG
                     LLYEQVCNGLKEAGYDYQTTEQTVTVLGVPKHAKDASQGINAVIRLATILAPLQEHPA
                     LSFLATQAGQDGTGRQIFGDIADEPSGHLSFNVAGLMINHERSEIRIDIRTPVLADKE
                     ELVELLTRCAQNYQLRYEEFDYLAPLYVAEDSKLVSTLMQIYQEKTGDNSPAISSGGA
                     TFARTMPNCVAFGALFPGAKQTEHQANECAVLEDLYRAMDIYAEAVYRLAT"
     gene            complement(19451..19741)
                     /locus_tag="VU534_000817"
                     /pseudo
     CDS             complement(19451..19741)
                     /locus_tag="VU534_000817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000501069.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(19729..19980)
                     /locus_tag="VU534_000818"
     CDS             complement(19729..19980)
                     /locus_tag="VU534_000818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000657761.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HEU1513430.1"
                     /translation="MKEFQFERKQRFSLRPYAIGACSVLLGTSLFFAGMGAQPVQDTE
                     TSSALISSHYLDEQDLSEKLKSELQWFELENKLLNLWEH"
     gene            complement(20379..21263)
                     /locus_tag="VU534_000819"
     CDS             complement(20379..21263)
                     /locus_tag="VU534_000819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001838996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HEU1513431.1"
                     /translation="MIFLIVCVLLLVIVTLSTVYVVRQQSVAIIERFGKYQKVANSGI
                     HIRLPFGIDSIAARIQLRLLQSDIVVETKTKDNVFVMMNVATQYRVNEQSVTDAYYKL
                     IRPESQIKSYIEDALRSSVPKLTLDELFEKKDEIALEVQHQVAEEMTTYGYIIVKTLI
                     TKVEPDAEVKQSMNEINAAQRKRVAAQELAEADKIKIVTAAEAEAEKDRLHGVGIAQQ
                     RKAIVDGLAESITELKEANVGMTEEQIMSILLTNQYLDTLNTFASKGNQTIFLPNTPN
                     GVDDIRTQILSALRAEKK"
     gene            complement(21408..22559)
                     /locus_tag="VU534_000820"
     CDS             complement(21408..22559)
                     /locus_tag="VU534_000820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HEU1513432.1"
                     /translation="MAIFYVPAVNLIGKGVVNEVGPYIKELGYKKALLVTDKYIEGSD
                     ILPKTLKPLDTEGIEYVIFSDVEPNPTCKNVTDGVAALQEHGCDFIISLGGGSPQDAA
                     SCISIMATNGGKPQDYEGLHKSAKKGLPVVAINTTAGTSAEITINYVITDEERKVKMV
                     MVDKNSLALISVNDPELMLSKPKGLTAATGMDALTHAVEALVTPGAYDVTKKLSIGAI
                     ELIKEYLPRAVENGHDIEAREGMVNAIFLGGMSFNNAGLGYVHSMAHQLGAVYNLPHG
                     VCCAMLLPVIERENAKRVPEAFRNVAKALGLHVEGKSDQECADYAIAEIEKLSETVGI
                     PKKLTELGIEEKDFDFEYLSKNALIDACAPGNPFMPTLEETIAFYKELF"
     gene            complement(22705..24471)
                     /locus_tag="VU534_000821"
     CDS             complement(22705..24471)
                     /locus_tag="VU534_000821"
                     /EC_number="5.3.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fucose isomerase"
                     /protein_id="HEU1513433.1"
                     /translation="MIQHPRIGIRPTIDGRRQGVRESLEVQTMNMAKSVADLISSTLK
                     YPDGEPVECVISPSTIGRVPEAAASHELFKKSNVCATITVTPCWCYGSETMDMSPDIP
                     HAIWGFNGTERPGAVYLAAVLASHAQKGIPAFGIYGRDVQEASDTDIPEDVKEKLLRY
                     ARAALATGLMRDTAYLSMGSVSMGIGGSIVNPDFFQEYLGMRNESVDMTEFTRRMDRG
                     IYDPEEFERALKWVKENVKEGFDHNREDLVLSREEKDRQWEFVIKMFMIGRDLMVGNP
                     RLAELGFEEEAVGHHALVAGFQGQRQWTDHFPNGDFMETFLNTQFDWNGIRKPFVFAT
                     ENDSLNGVSMLFNYLLTNTPQIFADVRTYWSPEAVKRVTGHTLEGRAAAGFLHLINSG
                     SCTLDGTGQATRDGKPIMKPFWELEESEVQAMLENTDFPPANREYFRGGGFSTRFLTK
                     GDMPVTMVRLNLLKGVGPVLQIAEGYTLELPEDVHHTLDNRTDPGWPTTWFAPRLTGK
                     GAFKSVYDVMNNWGANHGAITYGHIGADLITLASMLRIPVNMHNVPEEDIFRPKNWSL
                     FGTEDLESADYRACQLLGPLHK"
     gene            complement(24554..27670)
                     /locus_tag="VU534_000822"
     CDS             complement(24554..27670)
                     /locus_tag="VU534_000822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001031112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="discoidin domain-containing protein"
                     /protein_id="HEU1513434.1"
                     /translation="MNKEKIKRKLITILFVCIGMLCFGLLAGVKADNRVQMRTTINNE
                     SPLLLSPLYGNDNGNGLWWGNTLKGAWEAIPEDVKPYAAIELHPAKVCKPTSCIPRDT
                     KELREWYVKMLEEAQSLNIPVFLVIMSAGERNTVPPEWLDEQFQKYSVLKGVLNIENY
                     WIYNNQLAPHSAKYLEVCAKYGAHFIWHDHEKWFWETIMNDPTFFEASQKYHKNLVLA
                     TKNTPIRDDAGTDSIVSGFWLSGLCDNWGSSTDTWKWWEKHYTNTFETGRARDMRSYA
                     SEPESMIAMEMMNVYTGGGTVYNFECAAYTFMTNDVPTPAFTKGIIPFFRHAIQNPAP
                     SKEEVVNRTKAVFWNGEGRISSLNGFYQGLYSNDETMPLYNNGRYHILPVIHEKIDKE
                     KISSIFPNAKILTKNSEELSSKVNYLNSLYPKLYEGDGYAQRVGNSWYIYNSNANINK
                     NQQVMLPMYTNNTKSLSLDLTPHTYAVVKENPNNLHILLNNYRTDKTAMWALSGNFDA
                     SKSWKKEELELANWISKNYSINPVDNDFRTTTLTLKGHTGHKPQINISGDKNHYTYTE
                     NWDENTHVYTITVNHNGMVEMSINTEGTGPVSFPTPDKFNDGNLNIAYAKPTTQSSVD
                     YNGDPNRAVDGNRNGNFNSGSVTHTRADNPSWWEVDLKKMDKVGLVKIYNRTDAETQR
                     LSNFDVILYDNNRNEVAKKHVNNLSGESVSLDFKEKGARYIKVKLLTSGVPLSLAEVE
                     VFRESDGKQSEEDIDKITEDKVVSTNKVATQSSTNYEGVAALAVDGNKDGDYGHHSVT
                     HTKADSNAWWQVDLGEEFTVSKVDIYNRTDAEPQRLSNFDVIFLSSSGEEVFRRHFDK
                     VVDGLLSLKVPSVGAKLVKIELKSAAIPLSLAEVEVYGSKRTPKKLSNIALTKETRQS
                     STDYNGFSRLAVDGNKNGDYGHHSVTHTKEDSPSWWEIDLAQTEELEKLIIYNRTDAE
                     IQRLSNFDIIIYDSNDYEVFTQHIDSLESNNLSIDLKGLKGKKVRISLRSAGIPLSLA
                     EVEVYTYK"
     gene            complement(27680..29974)
                     /locus_tag="VU534_000823"
     CDS             complement(27680..29974)
                     /locus_tag="VU534_000823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 95 protein"
                     /protein_id="HEU1513435.1"
                     /translation="MKLWYKKAAANWNEALPIGNGHLGGMIYGSATKECIQLNDETIW
                     YRGKSDRNNPDSLLHLKKIREYLLDGEIQKAEELIKLTVFATPRDQSHYELLGELYIE
                     HIDIQSCALSLYERELDLDTAISNVVFEPNSCNLQIKREYFTSFNKNILCCRIVSSVQ
                     NTLNLNINLGRNKRFNDEVSKLDSSTILMSASAGGRKGVQFKVVCHSKVTDGEVSVLG
                     ETIVIRNATEVFLYLKSMTDYWGNIDISSLQGEFSSIDYFTEKDEHVKKYQEQFNRVD
                     FKLDYSKGCLSIPTNLLLENTKKYSNYLTNLLFHYGRYLLISSSQPNGLPANLQGIWC
                     DELNPIWGSKYTININTQMNYWMVGPCDLPEVEYPLFDMLERMREPGRLTAKKMYGAR
                     GFTAHHNTDGFGDTAPQSHAMGAAIWVLTIPWLCTHIWEHYLYFQDERILTEHFEMIK
                     EAFLFFEDYLFEVDGYLMTGPSVSPENKYRLKNGIEGNACLSSTIDNQILRYFCDSCI
                     GIAKQLGDNSDFISRVKELKKKLPKTKIGSNGQIQEWLEDYEEVEPGHRHISPLFGLY
                     PYNEIDIHKTPELAEAAKITINRRLSNANFLSSQEREQAINNWLVSGLHASTQTGWSA
                     AWLIHFFARLYQGEPAYNQINGLLNNATLGNLFLDHPPFQIDGNLGLVSGICELLVQS
                     HHNWLSLIPALPSAWSEGEVKGFRVRGGYKVSFAWKNGDITFLKLEGGNKDQKVRVRI
                     YGKNTDVQNIELVFNSEKIIELNF"
     gene            complement(30033..30833)
                     /locus_tag="VU534_000824"
     CDS             complement(30033..30833)
                     /locus_tag="VU534_000824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEU1513436.1"
                     /translation="MMNNKVTKVELKKVFKRSFMYGSSWNYERMQNLGFLYTILPVLK
                     KLYPDKDSASPAMKRHLEFFNTHQTAAPFILGVTSAMEEQEGNEGAASITGIKVGLMG
                     PLAGLGDSLFWLTLVPICFSIGASYSKDGGALGIFIALILFNIINIPVKYFGLKYGYT
                     KGSSLIQENNTKGTLNRVTSMATALGLVLVGGLIPSMVGINFGLEFKQGELVISVQEM
                     ITKLIPGFIPMALTLLMCKLIRKGKNPVVLIFSVMAIGVILVVLGILK"
     gene            complement(30830..31603)
                     /locus_tag="VU534_000825"
     CDS             complement(30830..31603)
                     /locus_tag="VU534_000825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000899624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HEU1513437.1"
                     /translation="MLFTQALLVTLVGIIATIDYNGPLFMIHRPLVTSAMVGLVLGDF
                     TQGVLIGSALELTWLGVTGIGGYTPPDTISGAIIGTAFGILSGQGETAGIAIAVPIAV
                     ATQQLDVLAKTLDVYFVKKADNDAKNGDYSKIGFYHYSSLVLITLFKIVPIFLAIMLG
                     GEYVADLFAKVPPIVMQGLNSAGALLPSIGFGMLLNMMLKKNMWVFLLIGFICSVYGG
                     MSTIGISLVGIAVAYFYDMIGSKPQETTSSSDVEEDLDL"
     gene            complement(31628..32098)
                     /locus_tag="VU534_000826"
     CDS             complement(31628..32098)
                     /locus_tag="VU534_000826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000020992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEU1513438.1"
                     /translation="MSIEFVRIDDRLVHGQVVTTWLKKYDIEQVIIVNDRISEDKTRQ
                     SILKISAPVGLKIVFFSVKRFVEVLNSVPIKKRTMLIYTNPKDVYDSIEGNLKLEYLN
                     VGQMSKTEENEKVTGGVALGEEDKYYFKKIVDKGTRVEIQMVPNDKVTMLEKFL"
     gene            complement(32089..32520)
                     /locus_tag="VU534_000827"
     CDS             complement(32089..32520)
                     /locus_tag="VU534_000827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000483177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEU1513439.1"
                     /translation="MFNRGILVASHGNFASGALMTAEMFVGETTNDRVRTLGLMPGEN
                     IVEFEHYFKNQVDELLDSNQEVIVLTDLIGGSPNNVALSRFLNLDSVDIVTGFNIPLL
                     VELISSYDSKINLEEIVHNAQNSLFNVKQQLNVEEEEDLCL"
     gene            complement(32510..32953)
                     /locus_tag="VU534_000828"
     CDS             complement(32510..32953)
                     /locus_tag="VU534_000828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000912114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RbsD/FucU family protein"
                     /protein_id="HEU1513440.1"
                     /translation="MLKHIPKNISPDLLKTLMEMGHGDEIVLADANYPSASCANKLIR
                     CDGVNIPELLDSILYLMPLDSYVDSSIQFMNVVSGDDIPKIWGTYRQMIEGHGTDLKT
                     ITYLRREDFYERSKKAYAIVATGETSLYANIILKKGVVVERENVQ"
     gene            complement(32965..33603)
                     /locus_tag="VU534_000829"
     CDS             complement(32965..33603)
                     /locus_tag="VU534_000829"
                     /EC_number="4.1.2.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001286141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fuculose-phosphate aldolase"
                     /protein_id="HEU1513441.1"
                     /translation="MSDVKQELIKYGKKLVETDLTKGTGGNLSVFDREKQLMAITPSG
                     IDFFEIKESDIVVMDINGNVVEGERLPSSEWYMHLIQYQTRDDIDAIIHAHTTYATVL
                     ACLREPLPASHYMIAVAGKDVRVAEYATYGTKELAVNAAKAMEGRRAVLLANHGILAG
                     AQNLLNAFNIVEEVEYCAKIYCLAKNFGEPVVLPDEEMELMAEKFKTYGQRK"
     gene            complement(33718..35121)
                     /locus_tag="VU534_000830"
     CDS             complement(33718..35121)
                     /locus_tag="VU534_000830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000388528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulokinase"
                     /protein_id="HEU1513442.1"
                     /translation="MEAVLAIDLGATSGRAIVGYLSENKLVMEEINRFSNLPIRVKGH
                     LSWDIDFLLAKILESIRLANTSYKILSIGIDTWGVDFGLIDNEGKLLLQPVHYRDERT
                     KGVLKEISEMTELEKLYSETGNQIMEINTLFQLFKARQESPDSFYKTNKILLMPDLFN
                     YLLTGKFATEKSIASTTQLFDPRSQNWNQNILKLFELDSSLLPEIVSEGNVLGRIKEE
                     YGLGDIPVVNVCSHDTASAIVSVPKTEGSLFISSGTWSLVGVELTSPILTTESFSYGF
                     TNEVGKDGVITFLKNCTGLWIIEELRRSFERRGKAYSFDDIRTMVEKEKENLPLIDTE
                     STEFATESDMHKTLTEYLAYHHETREWTDGQLFKIVYESLAETYRKAIELLEELTHKV
                     YKRIYVIGGGARASYFNQMIADRTGKEVLTGLTEATAVGNIVVQLIAMGQLKGMEEAH
                     HVIEEFLQLESYYSQKN"
     gene            35297..36070
                     /locus_tag="VU534_000831"
     CDS             35297..36070
                     /locus_tag="VU534_000831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEU1513443.1"
                     /translation="MIKDERVLELIEIIKKKKRIAVKELAEITFSSTSTLRRDLIFLE
                     NQGLIKRKHGYVTLSSMNTIELSHQIREGESTRQKRLIASLAKDFIRSGMCIYLDSST
                     TVYELCPYLSELDNLIIFTNGLHTAQTLSETVKDSSKIFITSGEVKHQSCSVVNYDKE
                     NSLLDHFNIDLAFCSARGIDDQYVYEASLSQAISKKNIIDKAHETILLIDSSKFYKTG
                     FFKINPLSKYTTFISDTVPDQKLLDAVELFDGEWVSDIQ"
     gene            complement(37230..38735)
                     /gene="adcA"
                     /locus_tag="VU534_000832"
     CDS             complement(37230..38735)
                     /gene="adcA"
                     /locus_tag="VU534_000832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding
                     lipoprotein AdcA"
                     /protein_id="HEU1513444.1"
                     /translation="MKKISLLLASLCALFLVACSNQKQADGKLNIVTTFYPVYEFTKQ
                     VAGDTANVELLIGAGTEPHEYEPSAKAVAKIQDADTFVYENENMETWVPKLLDTLDKK
                     KVKTIKATGDMLLLPGGEEEEGDHDHGEEGHHHEFDPHVWLSPVRAIKLVEHIRDSLS
                     ADYPDKKETFEKNAAAYIEKLQALDKAYAEGLSQAKQKSFVTQHAAFNYLALDYGLKQ
                     VAISGLSPDAEPSAARLAELTEYVKKNKIAYIYFEENASQALANTLSKEAGVKTDVLN
                     PLESLTEEDTKAGENYISVMEKNLKALKQTTDQEGPAIEPEKAEDTKTVQNGYFEDAA
                     VKDRTLSDYAGNWQSVYPFLEDGTFDQVFDYKAKLTGKMTQAEYKAYYTKGYHTDVTK
                     INITDNTMEFVQGGQSKKYTYKYVGKKILTYKKGNRGVRFLFEATDADAGQFKYVQFS
                     DHNVAPVKAEHFHIFFGGTSQEALFEEMDNWPTYYPDNLSGQEIAQEMLAH"
     gene            complement(38745..39551)
                     /locus_tag="VU534_000833"
     CDS             complement(38745..39551)
                     /locus_tag="VU534_000833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HEU1513445.1"
                     /translation="MLSLLSYDFIQRAFLAVIAMSLFSPVLGTFLILRRQSLMSDTLS
                     HVSLSGVAFGLVLGISPTVSTIAIVLIAAVFLEYLRTVYKSFMEIGTAILMSTGLAVS
                     LIVMSKGKSSSSMSLDQYLFGSIVTISEEQVISLFVIAAVVLILTFLFLRPMYILTFD
                     EDTAFVDGLPVRTMSILFNMVTGVAIALMIPAAGALLVSTIMVLPASIALRLGKNFKS
                     VMLLASAIGFLGMVAGLYISYYAETPASASITIIFVTVFILISLVRRFIK"
     gene            complement(39544..40248)
                     /locus_tag="VU534_000834"
     CDS             complement(39544..40248)
                     /locus_tag="VU534_000834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HEU1513446.1"
                     /translation="MRYITVEDLSFYYDKEPVLEHINYCVDSGEFVTLTGENGAAKTT
                     LIKASLGILQPRIGKVAISKTNTQGKKLRIAYLPQQIASFNAGFPSTVYEFVKSGRYP
                     RKGWFRRLNAHDEEHIKASLDSVGMWEHRDKRLGSLSGGQKQRAVIARMFASDPDVFI
                     LDEPTTGMDAGSKNEFYELMHHSAHHHGKAVLMITHDPEEVKDYADRNIHLVRNQDSP
                     WRCFNVHENGQEVGHA"
     gene            complement(40248..40688)
                     /gene="adcR"
                     /locus_tag="VU534_000835"
     CDS             complement(40248..40688)
                     /gene="adcR"
                     /locus_tag="VU534_000835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001249319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent transcriptional regulator AdcR"
                     /protein_id="HEU1513447.1"
                     /translation="MRQLAKDINAFLNEVILQAENQHEILIGHCTSEVALTNTQEHIL
                     MLLSEESLTNSELARRLNVSQAAVTKAIKSLVKEGMLETSKDSKDARVIFYQLTDLAR
                     PIAEEHHHHHEHTLLTYEQVATQFTPNEQKVIQRFLTALVGEIK"
     gene            complement(40843..42111)
                     /gene="dltD"
                     /locus_tag="VU534_000836"
     CDS             complement(40843..42111)
                     /gene="dltD"
                     /locus_tag="VU534_000836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000919885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HEU1513448.1"
                     /translation="MLKRLWMIFGPVLIAGLLVFLLIFFYPTEMHHNLGAEKRSAVAT
                     TIDSFKERSQKVRALSDPNVRFVPFFGSSEWLRFDGAHPAVLAEKYNRSYRPYLLGQG
                     GAASLNQYFGMQQMLPQLENKQVVYVISPQWFSKNGYDPAAFQQYFNGDQLTSFLKHQ
                     SGDQASQYAATRLLQQFPNVAMKDLVQKLASKEELSTADNEMIELLARFNERQASFFG
                     QFSVRGYVNYDKHVAKYLKILPDQFSYQAIEDVVKADAEKNTSNNEMGMENYFYNEQI
                     KKDLKKLKDSQKSFTYLKSPEYNDLQLVLTQFSKSKVNPIFIIPPVNKKWMNYAGLRE
                     DMYQQTVQKIRYQLESQGFTNIADFSKDGGEPFFMKDTIHLGWLGWLAFDKAVDPFLS
                     NPTPAPTYHLNERFFSKDWATYDGDVKEFQ"
     gene            complement(42104..42343)
                     /gene="dltC"
                     /locus_tag="VU534_000837"
     CDS             complement(42104..42343)
                     /gene="dltC"
                     /locus_tag="VU534_000837"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005591431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HEU1513449.1"
                     /translation="MDIKSEVIEIIDELFMEDVSDMMDEDLFDAGVLDSMGTVELIVE
                     IENRFDIRVPVTEFGRDDWNTANKIIAGIVELQNA"
     gene            complement(42357..43601)
                     /gene="dltB"
                     /locus_tag="VU534_000838"
     CDS             complement(42357..43601)
                     /gene="dltB"
                     /locus_tag="VU534_000838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000969717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HEU1513450.1"
                     /translation="MMEFFQQLPHLEPYGNPQYFVYVIAATLPIFIGLFFKKRFAWYE
                     VLVSLFFIVTMLVGGKTNQLAALGIYLCWEILLLLFYKHYRKSKDGKWVFYLVSFLSL
                     LPIIFVKVQPAINGTQSLLGFLGISYLTFRSVGIVIELRDGVIKDFTLWEFLRFLLFM
                     PTFSSGPIDRFKRFNENYQAIPERDELMDMLDESVRYIMWGFLYKFILAHVLGETLLP
                     PLKNLALQSGGFFNLYALAVMYTFGLELFFDFAGYSMFALAISNLMGIRSPINFNKPF
                     LSRDLKEFWNRWHMSLSFWFRDFVFMRMVMVLTRKKVFKNRNVTSSMAYIVNMLIMGF
                     WHGVTWYYIAYGLFHGLGLVINDAWVRKKKTLNKERKKAGKAALPENRWIQLLGMVVT
                     FHVVMLSFLIFSGFLNNLWFKK"
     gene            complement(43598..45148)
                     /gene="dltA"
                     /locus_tag="VU534_000839"
     CDS             complement(43598..45148)
                     /gene="dltA"
                     /locus_tag="VU534_000839"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012972622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
                     /protein_id="HEU1513451.1"
                     /translation="MSNKPIADMIETIEHFAQTQPSYPVYNVLGQEHTYGDLKADSDS
                     LAAVIDQLGLPEKSPVVVFGGQEYEMLATFVALTKSGHAYIPIDSHSALERVSAILEV
                     AEPSLIIAISAFPLEQVSTPMINLAQVQEAFAQGNNYEITHPVKGDDNYYIIFTSGTT
                     GKPKGVQISHDNLLSFTNWMITDKEFATPSRPQMLAQPPYSFDLSVMYWAPTLALGGT
                     LFTLPSVITQDFKQLFAAIFSLPIAIWTSTPSFADMAMLSEYFNSEKMPGITHFYFDG
                     EELTVKTAQKLRERFPNARIINAYGPTEATVALSAVAVTDEMLATLKRLPIGYTKADS
                     PTFIIDEEGNKLPNGEQGEIIVSGPAVSKGYMNNPEKTAEAFFEFEDLPAYHTGDVGT
                     MTDEGLLLYGGRMDFQIKFNGYRIELEDVSQNLNKSRFIESAVAVPRYNKDHKVQNLL
                     AYVILKDGVREQFERDIDITKAIKEDLTDIMMSYMMPSKFLYRDSLPLTPNGKIDIKG
                     LINEVNKR"
     gene            complement(45169..45300)
                     /locus_tag="VU534_000840"
     CDS             complement(45169..45300)
                     /locus_tag="VU534_000840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="HEU1513452.1"
                     /translation="MKQRKELYLFLGRTALYFLIFLGLLYFFSYLGQGQGSFIYNEF"
     gene            complement(45614..46792)
                     /locus_tag="VU534_000841"
     CDS             complement(45614..46792)
                     /locus_tag="VU534_000841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEU1513453.1"
                     /translation="MSNSFVKLLVSQLFANLADIFFRVTIIANIYIISKSVIATSLVP
                     ILIGISSFVASLLVPLVTKRLALNRVLSLSQFGKTILLAILVGMFTVMQSVAPLVTYL
                     FVVAISILDGFAAPVSYAIVPRYATDLGKANSALSMTGEAVQLIGWGLGGLLFATIGL
                     LPTTCINLVLYIISSFLMLFLPNAEVEVLESETNLEILLKGWKLVARNPRLRLFVSAN
                     LLEIFSNTIWVSSIILVFVTELLNKTESYWGYSNTAYSIGIIISGLIAFRLSEKFLAA
                     KWESILFPLVAMEIVTLTILYFPNAQMFLLFSALVGMLSQLKEVPESVFLQETVEENH
                     LVNVYSVLEVISTLAFSVFVLLMSYITESFGISISFWLSAICLMIEAILIYIRRDYFK
                     "
BASE COUNT        14081 a        10282 c         8514 g        14303 t
ORIGIN      
        1 cacgtaaatc cagcaaactc aagccactaa cagctgaaga taaagcctat aaccatgcgc
       61 tatctaagga gagaagcaag gttgagaaca tctttgccaa agtaaaaacg tttaaaatgt
      121 tttcaacaac ctatcgaaat catcgtaaac gcttcggatt acgaatgaat ttgattgctg
      181 gtattatcaa tcatgaacta ggattctagt tttgcaggaa gtctattgaa atactaagcc
      241 tacacagact gatttcaatt ttaccattct tcatagtcaa aaccatcata atctggatat
      301 tgttctggcg acgttccaac cgaacgtacg agataagctt cttcgtcctc tgtctcgatt
      361 tctctcagca cttggcattc aaaacgccat tcatcaccga agtcgaaaat aaacttaaat
      421 ttttgtttga cacttaggct atccagatag acattttctg tgtaacgttc ttcaacatcg
      481 tcactaacaa agctacgaaa gtaagaatct gcatgactcc actcaacatt atccatgaaa
      541 aatgcgtgag catgatcatt tgcaaaatca aaactccata aaatcacatc tgctagttcc
      601 gctaacgttt ttgtttttgg aatctatata tgtcggtagc aacctttttt aaatttgacg
      661 gaaatgatcc aagcttctac agatgctggc ttttcagctt ctatttcttg ttttactaat
      721 tttaagtgta gcataatacc tccaattgct cttaggaaac attcactttc tgctatttta
      781 tcataagttt gtctaactgt agcatttgaa accagataat tcttctgttt cacgcgaaac
      841 accctgcgcc aagcaaggtg ttcttgtttt tatactcaat gaaaatcaaa gagcaaacta
      901 ggaagctagc tgcaggttgc tcaaaacact gttttgaggt tgcagatgga agctgacgtg
      961 gtttgaagag attttcgaag aatattaagt cgtataaatc gtcgacgctg tcgcaatggt
     1021 atgccactgg ttggctgtag ttgctgcgaa atccttgtct gcgtagaagt cagtaaatgg
     1081 taggatttca acttccagct cgtcgatgcg gtcaagctga ccagccagat aaacctcgat
     1141 acggctttct gctcgtttga tgcgttgcaa gagtccgccc atacggatgt caactgtatc
     1201 caaaccaaag accttgtttt ctttcagcca ttggtggcta aagagggcat ggaagtcttc
     1261 aatttggctt ctaagttctg gtaattcttg tctggcgatt tgttgtaaac tttctttatc
     1321 atccgcttgg taggcctgac gaatgcgtcg tcccacatct actttgctac ttaaaatagc
     1381 attcaactgg gcctgagttt caaagagata ggcatagttt ccagcttttt ctttaatgtt
     1441 agcaagcgtc tcagcagcct gagcgaagtg cggtttgtcc tgttcaggtg tcatgtgttg
     1501 atcaagaatc ggacaaagaa tatcctgata aaaaacatag cggttgggat tgataccgct
     1561 gagattgcct ggtaggtctg gtaagaggtt ggcaaggtca atctgcataa aatcctcaac
     1621 cgttagacca gtattggtct tgaagtgcgc agacaaacca tctaggtcat tgcgatagct
     1681 gagttctgcc cagatttgca agcttggtag gatagagaac tgggcagttt caccaccatt
     1741 gtctccccaa cccgttacga tgacttcttt aatctgattg gcacggcagg ctttattagc
     1801 ctcgatagcc actagacggc taaaatggtt gtgaggtgta aagccaatcc acttccaagc
     1861 tccccctgca aatgcaaggt catggctaat cttgtgatga ttgcggaaat tacggttgta
     1921 tttttcctcg ctatcctgat aataatccca gtaaaccaga gtcacacggt ctttgagacg
     1981 gtctaggtag acacgagttt cctctggaat ttccacatca cggtcgtact ggccatccgc
     2041 tgacatgagt ttgaagaaca tatcactcca catctggcag tggaaaccat atttgtcagc
     2101 aatatccagc acgcgctcca agtgttggca catgaggaga ctacgatcca caacaccgtt
     2161 cagaatcagg tagcgtccca aaccaaccaa gtgggcttcg tccatcccga tattgacctt
     2221 gcgagtcttc agtttagaca acgtggcaaa catgccatca atcaagtcat aaaccttttc
     2281 ttcgccaatg agaagaatgt cctctacatc acggagctcc tgcacttcct tgacacccca
     2341 tttgacaaag gccgacaagt gggccaaggt ctggatgcat ggtacaaagg tcacgtcaaa
     2401 ctgttgggca taggcttcga tttcctgcaa ctcctctgct gaataagctc cacggaaata
     2461 gccaaagtaa ggctgccctt caatctggta agtgtcttcc atgtaaatct caaaggttga
     2521 gtagcccatg agagccaata tctcaatcat ctgcttggca gaagccacat tcagcaccgc
     2581 atttcgagaa cagtcaacca tgtaagccaa atcttcgtaa gctgcttgtt cctcaatctc
     2641 tactttatca gcttctgcta gaactgttac caacaaggac aaggcacgat aaagttggtg
     2701 aggtttgcgg taggtcaatt gatagtgacc ttcctcaccc tcgatagaga tagatgcttg
     2761 gtcagactga gtgacagcca cttccacatc tggtagagaa atgtgacctt ttaaaacctc
     2821 aatagcttgc gtttgtttga gactaagtcc tgtaaatctt accattgctt ttcctcctgt
     2881 agccagttga caagagcacc gtagagattg gcatctgcgt gataggtgca ggcctggata
     2941 actggtgcga ccgtgtattc ttcgtaggca tcgacaaagt cttcaacagc cttcttgaca
     3001 ccttggataa aatctggatt ttgactgata gagccaccca gactgatgac acctggatcg
     3061 atcagatact ggatattgag caagccttgc gccagattgc ggttcatgcg ctcaatggct
     3121 tcttgacaaa ggatattacc agctgcggcc tcttggtaaa tcttgcgacc gtcccaatca
     3181 gtatgaccag atttttcaat cacgtatcgt accatattcc cagttgatgc tagttgcgac
     3241 cagttattaa gtttttcagc aggggcaagg gttgtcatgt agccaaattc tccacccaga
     3301 ccgtggcgac ctcgatgaag tctaccattg ataatcatgg ctccgccaat ccctgtccca
     3361 atcacgacac aggctgcatt ttcaagctct ggatgagcta gtagttcact gagtccaacg
     3421 cagttggcat cattttctaa atggacaggt agctgataag agctaagcgc ctcataccaa
     3481 gaaaagccat ggatgtaggg caccgcactg aagccatcaa tcacacctgt ctcttgattg
     3541 actgcacctg gaacgctcat agcaatccca ctgtaatcct gttctgacaa gcgttgatct
     3601 agccacgcta gtaaatcctc caagttttca ggcgttgaaa tacttgtctt atccagtatt
     3661 ttcccatcag gagtcagact ggcaaactta atcccagtcc ctccgatatc aatcgttgca
     3721 atggtcattg tttttaccat aaaaggggcg aatcagcagt tagttcttac tttttcgccc
     3781 ctcctttctt ttgatgttta ctttttgaaa ttaaatttct tcttttttga tgaattctgt
     3841 acgaatctct tgtggagcca atagtcctga atgaactggg tatggtcgtt caagtaggtc
     3901 aaggaagaga tgttgacttt ctggcacacg tacattttca ctacacatat tgtagtaacg
     3961 aagcacatag ccttcttcat tttcagctac cttaaaggct gttggacaaa cttgcggtat
     4021 gctgagaaca gaatggctca agaggctacc agtcgcaacc acgcttcctt cctgtctagc
     4081 aagctgaagg ctggtaaacg gtgtctgcaa ggctttggca cgacgatagg ctgagaagcg
     4141 ttcttgggct tggtggcatt caagtgcaaa ctcgacttca aactcccgca agcattgtgc
     4201 ttctggcgtt gggaagtagc cccagtcacc tagctcacct gatgcacgca aaatggtcac
     4261 ggcaatggtg ttatccccaa ggatttcgta ttcattcaat cccttgttgg atacagtcac
     4321 ccctttttca tcgtcataca gactgacaaa agcttgttgg tgttgaggat tttcagggtt
     4381 ttcccatgaa gcagctggtt tgtttggtcg tgtcaccacc tcatagatac tttcagaatc
     4441 attgcttgga cgcgtgttat gagtcttgac caagagacgg atacggtgat ccttggcagt
     4501 gttagtaaag cgagtcttga agcggatttg tggattgtca acgaagacag tcaactcagt
     4561 ttccagagga atgtttgtca attcttctga ccgtccagcc tcacgcttca taaactcgat
     4621 gataccttgt tgctcttctt ctagcttttc atccgcactg acaggcacgg tcaattcatg
     4681 tttgagcaag attttagcat agcaagctgt gttttccaag acctcgtggc ccttaagctc
     4741 tgcaaagatt ggctctgttc cttttggttg gaaatagata tactcgtttc cgatgtcccc
     4801 acggtcttca aagcggataa agtcttcata ggcttcgtga gttgtcttgt catagactgt
     4861 gatgttgtca tccacactca ccgttacgaa tggtgtatca atcactccgt tttggtaaat
     4921 accctcacgg tgttcttgtt ttccttccag caattggaag gttgtccaag aaagcggcgc
     4981 taggtgaact ggaatggtca cgcgcacttg acgagcaata cgagcttggc ggaacttgtc
     5041 ttttggtaaa ttatactcaa aattagctcc gaggtcttcg attgtagcct ctacaggacg
     5101 accatccaag tcctccacac ggtaacttgg caagataaga gcagccatct ttttgtagcc
     5161 ttctgttggg tgcaattcct tgaaatcaca agtcgccaca tcaatcactg tgctgacagt
     5221 atcgacctta tcatgcaagc ctgtgttaat gacagtaaag agatagtcac tttgagcctt
     5281 atccgtagca attttaccct tccactcgtt gagcaagtta cttttaacaa agtttcctac
     5341 ttggttgacc ttggcaaaac gcgtttccat ctcgcggtga acttcgtcca cgctacagcc
     5401 acagatacta tcatgtggcg cattctgcaa aagtgttttc caagcatagg tcaactggtc
     5461 cttgtggttg tgtccaccag tgataatagt caagggttct accacttgct ctaggaggtt
     5521 gctattttct tggaaggctt gttttaggta aatgcgggat gaagaagtgt tggcaagtgt
     5581 gtaccagcca tctgtttcct gactggtcaa ctcgcctgta acagttgata agtgttcagg
     5641 aagcgcacct tctacagctt gaacatattc atcaaaagaa ctatgaacaa agattacatc
     5701 cgggaagagt tcatttgcca cacgaatggc ttcgctcaga tttttctgta caggctggtg
     5761 gtcacagccg ttcatcatca accattggtt ggtcgaagcg taggcacgca catctgacaa
     5821 tttttgtttc cagaaggtca aggcctcatc tttgtcaact ggaatttcat tcccgttact
     5881 gtaccagttg gcaaagagaa tacctaaaac acgactacca tccacaccct gccagtacat
     5941 ttctgaaaac tgagacgtaa actgctcatc ttcaaggact tggttgtcaa atccaatcgg
     6001 cttcacacca cgaccaaagg ccgccacgtg aatgcctgat ttttgaagaa tttgaggcgc
     6061 ttgtcccata tttccaaagg tatctggaaa gtagccaatc tgggttgatt taccccattt
     6121 ggcagcttct tgttgaccaa tcaaggtatt gcggacattg gcttcactgg agatcaagta
     6181 gtcatcctgc aagatgtaaa agggaccaat tttaagtttg ccctcgtcaa tgtagcgttg
     6241 gaccttgtcg cgattttcag ggcgaatttg taagtagtca tcaaggacaa tagtttgtcc
     6301 atccaagtgg aaactcttga actcagggtc attttcaaag agatcaaaga gattgtcaaa
     6361 caattccacc aactgcatac gatggctttc aaaaggcaag taccactcac gatcccagtg
     6421 actatgtgag ataatatgta caacaacatt ttccatgaag taaaacctca ttctaaattt
     6481 aaattttaac gttttaaatg taaacttgtg attctgataa gaatcggttg agctaaagcg
     6541 agccccttag cgaatatcca agtaatccaa gaccaactca cagaacatca tgttagccca
     6601 ggagaaccat tcacgagagt agagggtcgg atcatctaca tgaaagcttt cgtgcatgac
     6661 acctgtacca ccatcgcagg caaccagctg atccagcaag aattttttct ctgccttatc
     6721 tcttgttgtc aagccttgga tagaaagggc gattggccag atatagcgat agaaggtatg
     6781 agaactgccg agaccgcttg cgtattctcc ttggtagaag tatggatttt cagagctcaa
     6841 aatggtacga cgagtagctt gatacacttc atcatcgacc gaacagtagc ccagataggg
     6901 cgcagctagt agacttggta catttggatc atccatgatg ctggcatttc ctaggccatc
     6961 cacttcaaaa gcgtaaatct tttcgccctt gctgttggtg gtgtaagcgt agtttttgat
     7021 tccttcttgg atttcatcct gaagacgctt ggcatcagca ataacactct ggctatcagc
     7081 taggtttaat gctgcgaaga tttcttgcac ataacccaag actactacag caaacatatt
     7141 tgacggaatc aagtaactat actggcaaca gtcatcactc ggacgaaaag ctgaccaagt
     7201 catacctgtc actgcaaagt caggtccaaa gccatcattt accaaggtgt cttccttacg
     7261 gtccgtatct cggacaaaac gataaggaga gttcttgtgg tcttgttcca ccgtccacag
     7321 atggagaatt tccttagtcg ctgcgacaaa aatctcatca aactgactag tctcgccagt
     7381 ctctttccag aggagataag ccaactgcaa aggatagcaa agcgaatcca cctcatactt
     7441 gcgctcccag atccagccgt taaggtctgt gtggtcagtc tcgtggtgcc ctttccagtt
     7501 ctcctcaatg ttgaaggagt tagcataggg atccttgagt accaaggtca tctgacgttt
     7561 gaccaaacct gcaatggtct gacgcaggag ggcatctctt ttagctacat gaaggtaggg
     7621 tctgagttgg gctgtcgaat ctcgaagcca catggcagga atatccccag tcaagacaaa
     7681 agttgaacca tcttctaaga tttcaaccgt attgtccaag gtatcggtgt agcaacgctc
     7741 gaaaacatcc acccactctg gatagtcctt agcccgctct gctacttcat ctagccactc
     7801 tctgacaatt tctttcgaat aaaccatttt aaattttacc tctttcaaac aagtttcatg
     7861 ttcagtatat agcttttgag acagaaaata catacacaaa tgatagtcat ttttctacaa
     7921 aatagttatt tttgaaactc cttttctaaa ggccctcttt ttctgatata atgtagaaaa
     7981 acagctaaag gaaagactat gaaaccacta cttgaaacca tcgatacccg ctttggaact
     8041 accaacaagc atgccttttc tcggggaaat accctgccat acacaggcgt gccttttggg
     8101 atgaattact ttgtgcccca gaccagtgac caggatggat cttggttttt tgatccacat
     8161 ctgcctatct ttcaggggat tcgattaact caccagccca gtccttggat tggggactac
     8221 tcttggctcc ttctgacacc tgtcaccagt caactggggg gagacagcct ctttcaccgc
     8281 cagtcttctt atgatataga taaagcttgc ttccagcctc actatttgaa gctcttttct
     8341 ctgcgttatc agattgaaac ccagctcaca ccgacttgct atggtgcttc tattcgtttg
     8401 aatcaaaagc aaggcaaagc cctctccctc tatcttcacg cagcagatga actgacagta
     8461 gagcaagtag ataagcggac tcttgccctg cgacaagaag gtaaaactga aactaacaaa
     8521 aattcgctaa cgatgttcac tgccctgcaa atgaacacgg atattcttgc tatcagccaa
     8581 gaagctggag actggcgaat tgacttagca agtagtcaaa ccgagatgca actagccact
     8641 tctttcatct ctccttctca agctctaatc aatctacctc aagaagattt tgatagctgt
     8701 aaatcaagtg cccaagtgga ttgggaaaat ctcctccatc gttttgacat tatagagaca
     8761 ggagaggctg accgaacctt ctttgaccac tgcctctaca gactcttcct cttcccacag
     8821 actttttatg agattaatga atcagggcaa gccatccaca tggatctggc tactggtact
     8881 gtcaagcctg gtgtcctctt tagcaacaat ggtttctggg ataccttccg caccaccttc
     8941 cccctctttg cccttatcat accggagcac tatcaacgct ttttagaagg tttcctcaat
     9001 agctaccgcg atactggttt ccttccaaaa tggctggctc cagatgaacg gggtatgatg
     9061 ccaggtacac ttttagacgg tattatcgca gatagcgcct gcaaggacat gacccccgac
     9121 ctagaaggag aactcttcca agccatgctc gaaacagcca gcaaagccga ccctctcggc
     9181 atcaatggcc gccacggact agcccaatac caagaactag gttacctctc taccgaccac
     9241 cacgaaagtg ttagccatac tctagactat gcctatagtg acttttgtat cgccagctgt
     9301 gccaaaaaac tagagaacat agaaatcgct gaaacctaca aggctgcttc acaaaattac
     9361 cgccagctat ttgacgctga gacaggttac atgcgagcac gagacaatca aggaaacttt
     9421 caccctgact tctctcctta tagttggggg cgagactacg ctgaatgctc tgccattcaa
     9481 gctactttag gcgttctcca cgacatccct ggcttaatcc aactgatggg tggaaaagaa
     9541 acctttagca actatctttt gaaagcctgt caagatgctc ccctctttga aacaacaggc
     9601 tatggttacg aaattcacga aatgagcgag atggctactg ctccttttgg acaaatagcc
     9661 atttccaacc agcctagttt ccacattcct tatctcttcc gttacagcga ttaccctgac
     9721 tacactgccc ttcttatcaa gacgctccgt cagaaagctt ttcacccaag ttgggaagcc
     9781 tatcctggag atgaagacaa tggtagtctc tctgcttggt acatctggtc agctctcgga
     9841 ttttatccaa cctgtccagg aaaaccaagc tatgacctcg gaatccctct ctttgaccat
     9901 ctacgagtct acctcgctaa agaagataaa tggctggata tccatactaa acaaaaccac
     9961 aaccatttta actttgtcaa agaatgccga ctggacaaaa cactcgtatc aactattcaa
    10021 caccaagacc tcttaaaagc tgaacaacta actttcaccc tcagctggtt accaagtcac
    10081 taataaccaa aagaaccttt gcatcgcgca aaggttcttc ttttatgaaa cttggacttg
    10141 aagttgatcc acaagctgac catccaccgt taggttcaga tagaaatcca aggttttatc
    10201 tcctgcgaaa tacaaggttg gtagcgtcag acttttttca gtctcaccag tttgaaacgc
    10261 aaggacttga atctcatcct gataggcgac accatggaca cctgtccccg gttgaatcga
    10321 aatcttagct tctaaaggac cactacattc tctgcgctta actgtaaaat aggcattttc
    10381 tccctttgcc acagctaggc ttttttctgc aaatgctagt tcctgaacaa cttctttttt
    10441 tgataatcca ggagttttat aaagggaaat cttggtcaac aaaggcaaag cctgtgattc
    10501 tgtaatgact acacgtatct tctgtgcctc aacaactgct cctcgtaaga gacgtttgta
    10561 accaacagta tgacccgaac caaactcctg ccagacacca tccacctcta cttgcacatg
    10621 aaaagcagcg attcgttgcc ctagcttcaa atcttctctt aactcaatta catcaaaagt
    10681 tttaggagaa cctaagtcga gttctaactg gatgggcaag tctgcatcgc ttgcccaaga
    10741 gctggtctca aggccgtctg tcaaatggcg acaagcaaag tctgcggaaa gagctggacc
    10801 agatacctca gctcccagag ccaaatcttc tttatagagc tcattgcgat aggtcgcaaa
    10861 ttcataaagt cgttcaatat cctttgcatc aaagagccca gcttgattcg gcggaatatt
    10921 aagcaagagt ggagttcctc gccctactga gtgaaagtag atttcgacca actcctcgag
    10981 agacttagga tcctgatcct catggtagaa ccagcctgga cggatggaaa catctgcctc
    11041 tccgattgaa aaaatcgtgc ccgagggatc cccgtgctga agatagttca gctctgcttc
    11101 tgttcctagt ttatcaggat tcaccttttg ccacagtgga tcacctgcat accctcgttc
    11161 attgccaatc cagcggatac tggtgccttc tgttgaaaaa atcaagcaat cgccctgcag
    11221 gtcacgaatg gtttcaaacc atttttcaaa ttcataatta accttttgcg cgccctctcc
    11281 tctggcacca tccatccaaa cctcagcgaa cttaccagca ttcccatagt taggatttga
    11341 taagatttcc ttcaactgag ccagataata ggcattgtag tccgcttctc ggtccacatg
    11401 atagagggga ctatgggcat cccacggtga caggtagacc cccatatcca tatcaaactc
    11461 tgtggcagct tgggatactt caaggagcaa gtcgcccttt cctctcctcc aaggactgac
    11521 cttaaccgaa taatctgtgt gagctgtcgg ataaaggaca aagccatcgt ggtgcttgac
    11581 caccaaaatc aactttttga agcccgtttc cttgagcaca cgaacccact cacgcgcatc
    11641 caactgactc gggttaaagc gctcaggatc ctcctgtcca gtcccccatt cttggtcata
    11701 aaaggtatta ggaccgaagt ggataaaagc tgctagttca tctcccagat aagctagctg
    11761 agtctgactt ggtaacggtc catgcggttt gattttcttc atcgttatat atctccttct
    11821 ttagcaactt ctcttattca caaagttatc cacaggttgt ggataataaa ccatgatcta
    11881 acagtcagct ctttccaact ccaactggta ggctcaggat ttttctcctc aatattccct
    11941 cttcaaacag ctctgtcata tggttctgct aacacctctc agaatgctac tctccataat
    12001 tattctcagg cttctttcag gtcattgtgt gaagaccatt cactatccag acttttccac
    12061 agattgtgaa taagtgatta ttctaaacta tcacctcgtc gactataaca aaaaataaaa
    12121 agagggtcaa taagataatt atctcttcct aaatactcag aaaagattct ataatttgta
    12181 caattgaaca agaaatgctt ctccaaaatc tatcttcaaa agaatgttgc atctttttat
    12241 cctttcacac aaacatttct ctttatacag atccaagtga taaccagatg ataattggac
    12301 actttttgat catttgtata ttttttgaaa aattttttaa aaaaatttta tatccttttt
    12361 atagaagttt atgcatttgt atctatgtat tctatcctat gttatgtata ataacataaa
    12421 attgtgctaa acatcataat ttatattatt ttccgagaaa ttatagccat tgacattacc
    12481 taggaattgc gttataacat acatgtaagc ggtacccaaa atggtgccaa gtcaaaattt
    12541 ttaaggagga aaatacatgt cttcacatcc aattcaggtc ttctcagaaa ttgggaaact
    12601 gaaaaaagtt atgttgcacc gtccaggcaa ggagttagaa aacttgttgc cggactatct
    12661 tgaaaggctt ctttttgatg atattccttt cttggaagat gctcaaaaag aacatgatgc
    12721 atttgcccaa gctcttcgcg atgaaggaat tgaggttctc tacctagaac aactcgctgc
    12781 tgaatcattg acctctccag aaatccgcga tcaatttatc gaggaatact tagacgaagc
    12841 caacatccgt gatcgtcaaa ccaaggttgc tattcgtgaa ttgcttcacg gcatcaagga
    12901 caaccaagaa ttggttgaaa aaacaatggc tgggattcaa aaagttgaat tgccagaaat
    12961 tcctgacgaa gctaaagatc taactgactt agttgaatca gagtatccat ttgcaattga
    13021 cccgatgcca aacctctatt tcactcgcga cccatttgca acaattggaa acgccgtatc
    13081 gcttaaccac atgtttgcag acactcgtaa ccgtgaaaca ctctacggta agtatatctt
    13141 caaataccac ccaatctatg gcggaaaagt ggatttggtc tacaaccgtg aagaagatac
    13201 gcgtatcgaa ggtggagacg agttagttct ttctaaagac gtccttgcag taggtatctc
    13261 tcaacgtaca gacgcagctt ctatcgaaaa acttttggtc aacatcttca agaaaaatgt
    13321 tggcttcaag aaagttttgg cctttgaatt tgctaacaac cgtaaattca tgcacttgga
    13381 tactgtcttc actatggtag actatgacaa gttcactatt cacccagaaa tcgaaggcga
    13441 ccttcacgtt tactcagtta cttacgaaaa cgaaaaactt aaaatcgttg aagagaaagg
    13501 tgacttagct gaacttcttg ctcaaaacct tggtgtagaa aaagttcatt tgattcgttg
    13561 cggtggtggc aatatcgtag cagctgcgcg tgaacaatgg aacgacggtt ctaacacttt
    13621 gaccatcgca cctggtgtgg tagttgttta tgaccgcaat accgtgacca ataagatttt
    13681 ggaagaatac gggcttcgct tgattaagat tcgcggaagt gaattggttc ggggccgtgg
    13741 tggacctcgt tgtatgtcta tgccatttga acgtgaagaa gtgtaatcgc tgttcgatat
    13801 tcgtcaatag aaaatgtaaa aaatagaaag aggaaataat aaaatgacaa attcagtatt
    13861 ccaaggacgc agcttcttag cagaaaaaga ctttacccgt gcagagttag aataccttat
    13921 tggtctttca gctcacttga aagatttgaa aaaacgcaat attcaacacc actaccttgc
    13981 tggcaagaat atcgctctcc tatttgaaaa aacatctact cgtactcgtg cagcctttac
    14041 aactgcggct atcgaccttg gtgctcaccc agaatacctc ggagcaaatg atattcagtt
    14101 gggtaaaaaa gaatctactg aagatactgc taaagtattg ggacgtatgt ttgacgggat
    14161 tgaattccgc ggattcagcc aacgtatggt tgaagaattg gcagaattct caggcgttcc
    14221 agtatggaac ggtctaactg acgaatggca cccaactcaa atgctcgctg actacttgac
    14281 tgttcaagaa aacttcggtc gcttggaagg cttgacattg gtatactgtg gtgatggacg
    14341 taacaacgtt gccaacagct tgctcgtaac aggtgctatc cttggtgtca atgttcacat
    14401 cttctcacca aaagaactct tcccagaaaa agaaatcgtt gaattggcag aaggatttgc
    14461 taaagaaagt ggcgcacatg ttctcatcac tgaagatgct gatgaagcag ttaaagatgc
    14521 agacgttctt tacacagacg tttgggtatc aatgggtgaa gaagacaaat tcgcagaacg
    14581 tgtagctctt cttaaacctt accaagtcaa tatggactta gttaaaaaag caggcaatga
    14641 aaacttgatc ttcctacact gcttgccagc attccacgat actcacactg tttatggtaa
    14701 agacgttgct gaaaaatttg gtgtagaaga aatggaagta acagacgaag tcttccgcag
    14761 caagtacgct cgccacttcg atcaagcaga aaaccgtatg cacactatca aagctgttat
    14821 ggctgctaca cttggtaacc tttatattcc taaagtataa ttttagataa taaaccgtct
    14881 accaacagct atgagggctg cgactaatag ctttagtccg gtcctctttt atgtaatggt
    14941 aatctattat ttcttataaa atatgtgaaa aatcattaaa ttgaaatcta aacgcattct
    15001 attgagtgtg ataaaggaga atttatggca aatcgtaaaa ttgtagtagc tttgggagga
    15061 aatgcgattc tttcttctga cccatcagca aaggctcaac aagaagcttt agttgaaaca
    15121 gctaagcatc ttgtaaaatt gattaaaaat ggagatgatc tgattatcac tcacggtaat
    15181 ggacctcaag ttgggaatct cttgctccaa catttggcat cagactctga aaagaaccct
    15241 gccttcccac tcgactcact tgtcgctatg acagaaggta gcatcggttt ctggttgaaa
    15301 aatgctttgc aaaatgctct cttggatgaa ggcatcgaaa aaaatgttgc ctctgttgta
    15361 acgcaagttg tcgtagataa aaatgatcca gcttttgtta acttgagtaa accaatcggt
    15421 cctttctatt cagaagaaga agcaaaagca gaagccgaaa aaagcggagc gactttcaag
    15481 gaagatgctg gccgtggctg gcgtaaggtc gttgcctcac caaaacctgt tgacatcaaa
    15541 gaaattgaaa ccatccgtac tcttttaaat aatggtcaag tcgtcgtagc tgcaggtggt
    15601 ggcggtattc ccgtcgtcaa agaaaacaat ggacatttga ctggtgtcga agcggttatt
    15661 gataaagact tcgcttccca acgtttggca gaattggttg atgcagacct cttcatcgtt
    15721 ttgacaggtg tagattatgt atttgttaac tacaacaagc caaaccagga aaaattggaa
    15781 catgtgaatg ttgcccagct ggaagaatat atcaaacaag atcagtttgc accaggtagc
    15841 atgcttccaa aagtagaagc agctatcgct tttgtcaatg gtcgtccaga aggaaaagca
    15901 gttattactt cccttgaaaa tctaggcgcc ttgattgaat ctgaaagcgg aacaattatt
    15961 gaaaaaggat aagttgtttt actaataaga tgtattctat ttctagtatc tttatatcaa
    16021 attagaaatt attcttgaaa acatgtacaa tatttcaaaa gatactagtt ttagacttta
    16081 atatggtaaa acaaatataa atagaaagcg ttttcttgaa tgtttattta agaaagtagt
    16141 tggtttttta cactttgtta gacatcagga ggaaaaacaa atgagtgaaa aagctaaaaa
    16201 agggtttaag atgccttcat cttacaccgt attattgata atcattgcta ttatggcagt
    16261 gctaacttgg tttatccctg cgggggcctt tatagaaggt atttacgaga ctcagcctca
    16321 aaatccacaa gggatttggg atgtcctcat ggcaccgatt cgggctatgc taggtactca
    16381 tccagaggaa ggttcgctca ttaaagaaac gagcgcagcg attgatgtag ccttcttcat
    16441 ccttatggtt ggtggtttcc ttggcattgt caacaaaact ggtgctcttg acgtagggat
    16501 tgcctctatc gtgaagaagt ataagggccg cgaaaaaatg ttaattttgg tactgatgcc
    16561 tttgtttgcc ctcggtggta caacttatgg tatgggtgaa gaaacaatgg ccttctatcc
    16621 actccttgtg ccagttatga tggccgttgg ttttgatagc ctgactggtg ttgcaattat
    16681 tttgctcggt tctcaaatcg gctgtttggc atctactctg aatccatttg cgacaggtat
    16741 tgcttcagcg actgcgggag ttggtacagg ggacggtatc gtacttcgtc tgatcttctg
    16801 ggttaccttg actgctctta gtacttggtt tgtttaccgt tatgcggata agattcaaaa
    16861 agatccgact aagtcactgg tttatagtac tcgcaaagaa gatttgaaac actttaacgt
    16921 agaagaatct tcatctgtag aatctacact tagcagcaaa caaaaatcag ttctcttctt
    16981 atttgtgttg acattcatct tgatggtatt gagcttcatt ccatggacag accttggcgt
    17041 taccattttt gatgacttta atacttggtt gactggtctt ccagttattg gtaatattgt
    17101 cggttcatct acttctgcac taggtacttg gtacttccca gaaggcgcaa tgctctttgc
    17161 ctttatgggt atcctgattg gtgttattta tggtcttaaa gaagataaga ttatctcttc
    17221 cttcatgaat ggtgctgctg acttgctcag tgttgccttg atcgtagcga ttgctcgtgg
    17281 tattcaagtt atcatgaacg acggtatgat taccgataca atcctcaact ggggtaaaga
    17341 aggcttgagc ggtctatctt cacaagtctt tatcgttgta acttatatct tctatctacc
    17401 tatgtcattc ttgatcccat cttcatctgg tcttgccagc gcaactatgg gtatcatggc
    17461 tccacttgga gaatttgtaa atgtccgtcc tagcttgatt atcactgctt accaatctgc
    17521 ttcaggtgtc ttgaacttga ttgcaccaac atctggtatt gtgatgggag ctcttgcact
    17581 tggacgtatc aacattggta cttggtggaa attcatgggc aaactcgtag tcgctattat
    17641 tgtagtgacc atcgcccttc ttctccttgg aaccttcctt ccattcctat aaaatagtga
    17701 gtgaggtgat tccatgaaaa tagatataac aaatcaagtt aaagatgaat ttcttatatc
    17761 attaaaaacc ttgatttcct atccttcagt actcaatgaa ggagaaaatg gaacaccttt
    17821 tggacaagca atccaagatg tcctagaaaa aactttagag atttgtcgag acataggttt
    17881 cactacctat cttgacccta aaggttatta cggatatgca gaaatcggtc agggagcaga
    17941 gcttctggcc attctctgtc atttggatgt tgttccatca ggtgatgaag cagattggca
    18001 gacaccgcca tttgaagcaa ctatcaaaga cggctgggta ttcggacgtg gtgtccaaga
    18061 tgataaaggc ccttcgctcg cagctctcta tgcagtaaaa agcttgctgg accaaggtat
    18121 tcagttcaaa aagcgcgtac gctttatctt tggtaccgat gaggaaaccc tctggcgctg
    18181 catggcacgc tacaatacca tcgaagaaca ggccagtatg ggctttgcac ctgactcatc
    18241 ttttcctctg acctatgctg aaaaagggct tctacaggtc aaacttcatg gccctggatc
    18301 ggatcaacta gagcttgaag taggaggcgc ctttaacgtt gtaccagaca aggccaacta
    18361 ccaaggtctc ctctatgaac aggtttgtaa cggtctcaaa gaagctggtt atgattacca
    18421 aaccactgaa caaaccgtaa cggttctcgg agtgccaaag catgctaagg atgctagtca
    18481 aggtatcaat gctgtcatcc gactagctac cattcttgct cctctccaag aacaccctgc
    18541 tctcagtttt cttgcaacac aagcaggtca agacggcaca ggaagacaaa tctttggtga
    18601 tatagcagat gaaccttctg gtcacctatc ctttaatgtc gcaggtctca tgatcaatca
    18661 tgaacgttct gaaatccgta ttgacattcg gactcctgtc ttagctgaca aggaagaact
    18721 agtagagttg cttacaagat gtgcacaaaa ctaccaactc cgctacgaag agtttgacta
    18781 tctagcgcct ctatacgtcg cagaagacag taaactcgtt agcacactga tgcaaatcta
    18841 ccaagaaaag actggcgata acagtcctgc tatttcatcc ggtggtgcca cttttgctcg
    18901 caccatgcca aattgtgtag ccttcggcgc cttattccca ggagcgaagc agacagaaca
    18961 tcaggcaaat gaatgtgccg ttctagaaga tttgtaccgt gctatggata tttatgccga
    19021 agccgtctat cgacttgcaa cttaatcagg caactgtttc taccaaaaaa aatcgaccga
    19081 ttaatgaact gcaccccaaa agttagacag aataaatcta acttttgggg tgttttatta
    19141 tgaaattgag ttatgaagat aaagttcaga tctatgaact aagaaagcaa ggacaaagct
    19201 tcaaacagct ttcaaaaaga tttggtgtgg atgtttctgg tctaaagtca tctgaatctt
    19261 tgagatgagc tttataaatc gcttttttca gtttttgcac tggtgtttcg ataaactcaa
    19321 actttttagc cgtggtattg cctgatttta tagtatattg aaactagaat agtacacctc
    19381 tccttctaaa acatttttag aaatcgattt gactgtcctg atcgatttgt cctgttctta
    19441 tttcatttta ctatatttga gccacttcgt ctttaacggc tttattcata agctcttgta
    19501 atttttcttt actatcaatt acttctgatt ttccgttgta atttattgta ataggtttta
    19561 acttacctaa tttctcgaca cgctcattaa tttgatcttt tttgaaggct gcttatgttt
    19621 ttcctaagat tttttcaaaa atatatttat cagatagcgg tttgtcttct tcttcagctt
    19681 ggtttttgta ttaatttgaa acataaggaa caaatccttc atagtaacct aatgctccca
    19741 taagttcaaa agcttgtttt ctaattcaaa ccattgcaac tcagatttca gcttttcaga
    19801 taaatcctgc tcatccaaat aatgacttga aattagtgct gaactcgttt ctgtatcctg
    19861 tacaggctga gcacccatac cagcaaaaaa taaactcgtt cctagcaaga ccgaacaagc
    19921 tcctattgca tatggcctca aagaaaaacg ctgctttctc tcaaattgaa attctttcat
    19981 cccatctccc atcattcatt attactgtat attttgtata tcagaaatag tttgtattca
    20041 caaatctttc tagttattcc cttatcattc ctaattaagg gagataacat acaataattt
    20101 ttagttaaat gtatatcgat gttttttgtt tttcttaata aacgcaatac aaaaagagcc
    20161 tgttaccaag ctctttgtac tcaatgaaaa tcaaagagca aattaggaaa ctagccacag
    20221 gttgctcaaa acaccgtttt gaggttgcag atagaactga cgaagtcagc tcaaaacact
    20281 gttttgaggt tgcagataga actgacgaag tcagtaacat ctatacggca aggcgacgct
    20341 gacgtggttt gaagagattt tcgaagagta ttagtctatt atttcttctc agcgcgaagg
    20401 gctgacaaga tttgtgttcg gatatcatcc acaccatttg gagtatttgg taaaaagata
    20461 gtttgatttc ctttagaggc aaaggtattc aaggtatcca aatactggtt ggtcaagagg
    20521 atagacatga tttgttcttc tgtcatgcca acattggctt ccttgagttc ggtgatagac
    20581 tctgccaatc catccacaat cgccttacgt tgttgggcaa tccccacacc atgaaggcgg
    20641 tctttttctg cttctgcttc agctgcagtg acaattttaa tcttgtcagc ttccgccaat
    20701 tcttgtgctg cgacccgctt acgttgcgcc gcattgattt cattcatgga ttgcttaact
    20761 tctgcatctg gttcgacctt ggtaatcaag gttttcacga taatgtagcc gtaagtggtc
    20821 atttcttctg ctacttggtg ttgaacttca agggcaatct catctttttt ctcaaacaat
    20881 tcatccaagg ttaattttgg aacagaagag cgaagagcat cttcgatata agatttaatc
    20941 tgagattctg gacgtatgag tttatagtaa gcatctgtca cgctctgctc gttgacacgg
    21001 tactgagtcg ctacattcat cataacgaac acattgtcct tggtcttagt ctcaaccaca
    21061 atatcacttt gcaacaagcg caactgaatc cgtgctgcaa tcgagtcaat cccaaaaggc
    21121 aagcgaatat gaataccgct attagcaacc ttttggtatt tcccaaagcg ttcaataatc
    21181 gccaccgact gctgacgaac cacataaact gtactcagtg tgactatcac caataggagc
    21241 acacaaacaa tcagaaaaat catgaaaaat attgccataa tggaacctcc acaagtattt
    21301 ttctagtatt atagcacatt taaagaaggc tgtgccgttt ttactgcgat ttttcctgaa
    21361 atgtcaataa ttagaggtga attgtcctat tgtcgtccaa tctcttgcta aaataactct
    21421 ttataaaagg caatcgtttc ttctaaggtt ggcataaatg gatttcctgg tgcgcaggca
    21481 tcaatcaagg cattcttaga aaggtattca aagtcgaaat ctttttcttc aataccaagt
    21541 tcagtcagtt tcttaggaat acctactgtc tcagaaagct tctcaatctc agcaatcgca
    21601 taatcggcac attcttgatc tgatttacct tctacatgaa gtcccaaggc tttggcaaca
    21661 ttgcggaaag cttctggtac acgtttagca ttttcacgtt ctataactgg tagcaacatg
    21721 gcacagcaca cgccatgtgg caaattatat actgcaccga gttggtgagc cattgagtga
    21781 acatagccaa gaccagcatt attaaagctc ataccaccaa ggaagatggc attgaccata
    21841 ccttcacgcg cttcaatatc atgtccattt tctacagcac gaggaagata ttccttgata
    21901 agctcaatag caccaataga cagtttcttg gttacatcat aagcaccagg tgttaccaaa
    21961 gcttcaacag catgagtcag agcatccata ccagtagcag cagtcaggcc tttaggtttg
    22021 gaaagcatga gttcagggtc attaacagag ataagagcaa ggctattctt gtcaaccatt
    22081 accatcttaa ccttgcgttc ttcatcagta atcacatagt taatggtaat ttctgctgat
    22141 gtacctgccg ttgtattgat agccacaact ggcaagcctt ttttagcaga cttatgaagc
    22201 ccttcataat cctgtggttt tccaccattt gtagccatga tagaaataca actagctgca
    22261 tcctgtggag aacccccgcc aagactgatg ataaagtcac agccatgttc ttgcaaagca
    22321 gctaccccat ctgtgacatt tttacaagta gggtttggct ctacatcgct aaagatgaca
    22381 tattcgattc cttctgtatc cagtggtttt aaagtcttag gtaaaatatc actgccttcg
    22441 atgtacttat ctgtcaccaa aagtgccttt ttatagccaa gttccttgat ataaggaccc
    22501 acttcattta caacaccttt tccaataagg ttgactgccg gaacataaaa tatagccata
    22561 taattttcct cctgcgcctc cgcgctatct atttaacatc attatattac tttttgtatt
    22621 cgttttcaat tatttgtgaa ttgtttaaca aatcttttta aaaggatagg agggacgtaa
    22681 gttcacctcc tatataaaca agttttattt atgtagtggc cccaacaact gacatgcacg
    22741 atagtctgct gattctagat cttctgttcc aaataaggac caatttttag gtctaaagat
    22801 atcttcctca ggtacattat gcatattgac aggaattctc aacatagaag ccaaggtaat
    22861 caagtctgct ccaatgtgtc catatgttat ggctccgtga ttagctcccc aattattcat
    22921 gacgtcatag acagacttga aagcaccttt tcctgtcaaa cgtggagcaa accaagtagt
    22981 tggccatcct ggatctgtac gattatctaa agtatggtga acatcttcag gaagttcaag
    23041 tgtgtaacct tctgcaattt gtagcactgg accaacccct tttagaagat tgagacgtac
    23101 cattgttact ggcatatccc ccttcgtcaa gaaacgagtt gagaatcctc ctccacggaa
    23161 gtattcgcgg tttgctggtg ggaagtctgt attttcaagc atagcctgca cttcactttc
    23221 ttccaactcc cagaatggtt tcataatagg tttgccatct cgagtagctt gacctgtacc
    23281 atccaatgta caagaaccag agttgattag atgtaagaag ccagctgcag cacgaccctc
    23341 taaagtatgt cccgttacac gtttaacagc ctctgggctc caataagtac gcacatcagc
    23401 aaagatttgt ggagtatttg ttaatagata attaaagagc atagacacac catttagtga
    23461 atcattctct gtcgcaaata caaatggttt tcgaatacca ttccagtcaa actgagtatt
    23521 gaggaaagtt tccataaagt ccccatttgg aaaatggtct gtccactgac gttgaccttg
    23581 gaaaccagct actaaagcat ggtgaccaac cgcttcttcc tcaaaaccaa gttcagcaag
    23641 tcttgggtta ccaaccatta agtcacgtcc aatcatgaac atcttaataa caaattccca
    23701 ttgtctatct ttttcttcac ggcttaaaac aaggtcttca cggttatggt cgaatccttc
    23761 ttttacgttt tctttcaccc atttgagcgc acgttcgaac tcttcagggt cgtaaatacc
    23821 acggtccata cggcgcgtga actccgtcat atctaccgat tcatttcgca ttcctaagta
    23881 ttcttggaag aaatccggat ttacaataga accaccaatc cccatcgaaa cactacccat
    23941 tgataggtaa gcagtgtctc tcatcaagcc agttgcaaga gctgcacgcg catagcgtaa
    24001 aagtttttct ttgacatctt ctggaatatc tgtgtcacta gcttcctgaa catctcttcc
    24061 ataaatccca aaggctggaa tccctttttg agcatgtgaa gctagtacag ctgcaagata
    24121 gacagctcct gggcgttctg tcccattaaa tccccaaata gcatgaggaa tatctggaga
    24181 catatccata gtttcactac cataacacca gcatggtgta actgtaattg ttgcgcaaac
    24241 atttgatttt ttaaacaact catgggaagc tgcagcctct ggtacacggc caatagtaga
    24301 tggagaaatc acgcattcca caggttcccc atctggatat ttcaatgtgc ttgaaatcaa
    24361 atctgccaca cttttagcca tgttcattgt ttgcacttca agtgattcgc gtacaccttg
    24421 acgacgacca tcaatagtcg gacgaatccc aatacgtgga tgttgaatca tactattttc
    24481 ctcttatttt tctgtttctt tcatactacc atctccatta tatttacggt agcctgggtg
    24541 ataattttta aaattactta taagtataaa cctctacctc tgctaaactt aaaggaattc
    24601 ctgcgcttct caaagaaatt ctaacctttt ttcccttcag tccttttaag tctatggata
    24661 gattattgct ttctaaactg tcaatatgtt gtgtaaaaac ttcataatca tttgaatcat
    24721 atataataat atcaaaattt gataatctct gaatttcagc atctgttcta ttataaataa
    24781 ttaacttttc taattcttcg gtttgtgcta aatctatctc ccaccatgaa ggagaatctt
    24841 ctttggtatg agtcactgaa tgatgaccat aatctccgtt tttatttcca tcaactgcta
    24901 gacgagaaaa accattgtaa tccgttgaac tctgtcgagt ttcttttgtt aatgcaatat
    24961 tagaaagttt cttcggagtt ctctttgaac catagacttc aacttccgct aaacttaacg
    25021 gaatagctgc tgattttaat tctattttga ctagcttagc ccctacagaa ggtactttta
    25081 aagataacaa accatcaact actttatcaa aatgtcttct aaaaacttct tctcctgatg
    25141 aagatagaaa aataacatca aaattagata aacgctgagg ttcggcatct gttctattat
    25201 aaatatcaac tttagaaacc gtaaactctt ctcccagatc gacctgccac caagcgttag
    25261 aatctgcctt agtatgagtc accgaatgat gtccgtaatc tccatcttta ttaccatcaa
    25321 ctgctaaagc agctacaccc tcataattgg ttgaactttg agtagctacc ttatttgtag
    25381 agactacttt atcttctgtt attttatcta tatcctcttc agattgctta ccatctgatt
    25441 ctctaaaaac ctctacttct gctaaactca aaggcactcc actcgttagt aatttaactt
    25501 taatatacct tgctcctttt tctttgaaat ctagactaac agattcaccc gacaaattat
    25561 taacatgttt cttagcaact tcgtttctat tattgtcata tagaatcaca tcaaaattag
    25621 atagacgttg agtctcagca tctgtgcgat tataaatttt aacaagccca actttatcca
    25681 tttttttcaa atcgacttcc caccaagagg gattatctgc cctagtgtgt gttaccgaac
    25741 cagagttaaa attaccattt ctgttaccat ccacagctct attagggtct ccattgtaat
    25801 ctacagaact ttgtgttgtt ggttttgcat atgctatatt caaattacca tcattaaatt
    25861 tatctggtgt tgggaaagag actggacctg tcccctcagt atttatagac atctctacca
    25921 ttccattatg attaaccgta atggtataaa catgggtatt ctcatcccaa ttttctgtat
    25981 aagtataatg atttttatcg ccacttatat ttatctgagg tttatgacca gtatgccctt
    26041 ttaatgtaag tgttgttgtc ctaaagtcat tatctacagg attgatggaa taatttttgc
    26101 ttatccagtt cgctaactct aattcttctt tcttccaact ttttgatgca tcaaaatttc
    26161 ctgataatgc ccacatagct gtcttatctg tcctgtaatt attcaataaa atatgtaaat
    26221 tatttggatt ttctttaaca acagcgtaag tatgtggcgt caaatctaac gataacgact
    26281 ttgtattatt agtatacata ggcaacatta cttgctgatt tttattgata ttagcattac
    26341 tattataaat ataccaggaa ttacctacac gctgagcata cccatctcct tcataaagtt
    26401 ttggataaag cgagtttaaa tagttgactt tactagacaa ttcctcacta tttttagtca
    26461 aaatttttgc attagggaat atagatgaaa tcttttcctt atcaattttc tcatgtatta
    26521 caggaagaat atgatatctc ccattattat ataaaggcat tgtttcatca ttcgaataaa
    26581 gtccttgata aaatccgttt aatgaactaa tcctaccttc tccattccaa aatacagctt
    26641 ttgttctatt tacaacttct tccttacttg gagctggatt ttgtatagca tgtctaaaga
    26701 aaggaataat acctttagta aatgctggag ttggtacatc atttgtcata aatgtatacg
    26761 cggcacattc gaaattataa actgtgcctc ccccagtata tacattcatc atttccatag
    26821 caatcattga ttctggttcc gatgcatagg atctcatatc cctagctctt ccagtttcaa
    26881 atgtgtttgt ataatgtttt tcccaccatt tccatgtatc tgttgatgag ccccagttat
    26941 cacataagcc actcaaccaa aatccactaa cgatagaatc tgtacccgca tcatctctta
    27001 ttggcgtatt tttagttgcc aacaccaaat ttttatgata tttttgactc gcttcaaaga
    27061 atgtcggatc attcataata gtttcccaga accatttttc atgatcatgc cagataaaat
    27121 gcgctccata tttggcacaa acttccaaat atttagcact atgcggagct aactggttat
    27181 tgtaaatcca ataattctca atatttaaaa caccttttaa cacactatac ttttggaatt
    27241 gttcatctaa ccactctgga ggaactgtat tacgctctcc agccgacata ataaccaaga
    27301 aaactggaat gtttagactt tgagcttcct ccaacatctt gacataccat tctctcaatt
    27361 ctttcgtatc tcgtggaata caacttgttg gtttacagac ttttgcagga tgaagttcaa
    27421 tcgctgcata tggctttaca tcttcaggaa tagcttccca tgctcccttc aatgtgttcc
    27481 cccaccataa tccgttacca ttatcattgc catacaacgg agaaagcaac aatggcgatt
    27541 cattattaat cgtcgttctc atttgaacac gattatcagc cttaactcct gctaacaatc
    27601 caaaacataa catcccaata catacaaaca atattgtgat taattttctt tttatttttt
    27661 ctttattcat gacttatacc taaaaattta actcaataat tttttctgaa ttaaatacca
    27721 attcaatatt ttgtacatca gtatttttgc catatattct tactcttact ttttgatctt
    27781 tgtttcctcc ttccaatttt aggaatgtta tatccccatt tttccaagca aacgatacct
    27841 tatatcctcc tcttactctg aaacctttca cttctccttc tgaccaagca gaaggtaaag
    27901 ctggaattag tgataaccaa ttatgatggc tctgtactaa taattcacaa attccactca
    27961 ccaaacctaa attaccatca atttgaaatg gtggatggtc aagaaataaa ttgccaagag
    28021 tcgcattatt taacaaacca ttaatctggt tataagcagg ttcaccttga tatagtctcg
    28081 caaaaaaatg aatcagccat gcagcactcc aacctgtttg tgtactagca tgcaaaccac
    28141 ttactaacca attattaatc gcttgctccc tctcctgtga agataaaaaa ttagcgtttg
    28201 ataatctcct attgatagtg attttagctg cttctgctaa ttccggagtt ttatgaatat
    28261 caatctcatt ataaggataa agcccaaata gaggtgaaat gtgtctatgc ccaggctcta
    28321 cttcttcata atcttctaac cattcttgga tttgcccatt actacctatt tttgttttag
    28381 gtagtttctt ttttaactcc ttcacacgac taataaaatc cgaattgtct cctaattgtt
    28441 ttgcaatgcc aatgcatgaa tcacaaaaat atcttagaat ttgattatca attgtagatg
    28501 atagacaagc atttccttca ataccatttt ttaagcgata tttattttcc ggtgagacac
    28561 ttggacctgt catcaagtag ccatccacct caaataaata atcttcaaag aaaagaaatg
    28621 cttcttttat catttcaaaa tgttccgtaa gaatacgctc atcttggaaa tataaatagt
    28681 gttcccaaat atgagtacat aaccatggaa tagttaatac ccaaattgca gcccccatgg
    28741 catgagattg gggagccgta tcgccaaaac catccgtatt atgatgtgct gtaaaacctc
    28801 tagctccata cattttctta gcggttagtc ttcccggttc tctcattctt tcgagcatat
    28861 caaataatgg atattctact tctggtaaat cacatggacc taccatccaa taattcattt
    28921 gagtattaat attaatcgta tatttagaac cccaaattgg atttaattca tcacaccata
    28981 ttccttgaag attggcaggt aaaccattcg gttgactaga cgatattaac agatatcttc
    29041 cataatgaaa taacaagtta gtcaagtagt tactatactt tttagtgttt tcaagaagta
    29101 gattcgttgg aatgctaaga caacctttac tatagtctag tttaaaatca actctattaa
    29161 attgctcctg atattttttt acatgttcat ctttttctgt aaagtaatca atactactaa
    29221 attctccctg aagagaagaa atatctatat ttccccaata atccgtcatt gatttgagat
    29281 aaagaaatac ctctgtagca ttccgaataa ctattgtctc tcccaataca cttacttcac
    29341 catccgtaac cttagaatga catactactt taaactgaac accttttcta cctccagcag
    29401 aggccgacat taaaattgta cttgaatcca gtttagatac ttcgtcatta aaccgtttat
    29461 ttctacccaa attaatgttt aaatttaatg tgttttgaac tgatgacact atacggcaac
    29521 ataaaatatt cttattaaaa ctcgtaaaat attctctttt tatttgtaaa ttacaactat
    29581 taggctcaaa cacaacatta gaaatagctg tatctaaatc tagctctctt tcatacaatg
    29641 aaagagcaca agactgaata tctatatgct caatgtaaag ttccccaagt aattcatagt
    29701 ggctttgatc tcttggggta gcaaacactg ttaactttat caattcttcg gctttctgaa
    29761 tttctccatc taaaagatat tcccgaattt ttttaagatg caatagtgag tctggattat
    29821 ttctatctga ctttcctcta taccaaatag tctcatcgtt tagttgaata cattcttttg
    29881 tagctgaacc ataaatcata ccacctaaat gaccgttccc aatcggcaag gcttcattcc
    29941 aatttgcggc agctttctta taccataatt tcactcttta cctctcttcc aaaatggagg
    30001 tgatatccca aataccacct ccacactttc tactacttca aaattcctaa aacaactaga
    30061 ataactccaa tagccataac actaaagatt agtacaaccg gattctttcc ttttctaatt
    30121 aatttacaca ttaataaagt caaagccata gggataaatc ctggaattaa ttttgtaatc
    30181 atttcttgaa cagaaataac aagttccccc tgcttaaatt ctaatccaaa attaatacca
    30241 accattgatg gaatcaaacc acccactagt actagcccta atgctgtcgc catactcgta
    30301 acgcgattca atgttccttt tgtattattt tcttggataa gactagaacc cttagtatac
    30361 ccatatttca aaccgaaata tttaacagga atattaataa tattaaacaa tattaaggcg
    30421 ataaagatac ctaaagcacc gccgtcttta gaataagacg caccaatact aaaacagata
    30481 ggaactagtg tcagccagaa caaactatct cctagaccag ccagtggccc catcaagcca
    30541 actttaatac cagtaattga agctgcacct tcatttcctt cttgttcttc catagcggaa
    30601 gtaactccaa gaataaatgg tgccgctgtt tgatgagtat tgaaaaactc aaggtgacgt
    30661 ttcattgcag gagaagctga atctttgtct gggtatagtt ttttcaatac tggaagaatt
    30721 gtatatagaa aacctaggtt ctgcattctc tcatagttcc atgaagaacc atacataaaa
    30781 cttcgtttga aaactttttt aagttcaact ttagttactt tattattcat catagatcaa
    30841 gatcctcctc aacatcacta cttgaagttg tttcttgtgg tttgcttcca atcatatcgt
    30901 agaagtatgc taccgcaata ccaactagtg agatcccaat ggttgacatt cctccataca
    30961 cagaacaaat gaatccaatc aacaagaata cccacatatt tttcttgagc atcatattta
    31021 aaagcatacc aaaaccaatt gaaggtagta aagcacctgc agagttaagt ccctgcataa
    31081 cgattggtgg aaccttagca aacaagtctg ccacatattc ccctccaagc ataatagcta
    31141 ggaaaattgg tacaatttta aataacgtga ttaaaaccaa acttgaataa tgataaaaac
    31201 cgatctttga ataatctccg tttttagcat cattatcagc ttttttcaca aaataaacat
    31261 ctaaagtttt tgcaagaaca tccaactgtt gggtagcaac tgcaattgga actgctatag
    31321 cgataccagc agtttctcct tgaccagata aaataccaaa tgcagtacca ataatcgcac
    31381 ctgaaatagt atctggtgga gtataacctc caatacctgt tacaccgagc caagttaatt
    31441 caagagctga accaataaga acaccttggg tgaaatctcc taatactaag ccaaccattg
    31501 cacttgtaac taacggacgg tgaatcataa ataacggtcc attatagtca atagtggcaa
    31561 taatcccaac taatgtcacc agtaatgctt gtgtgaatag catatactgt acctccttaa
    31621 attattttta taaaaatttt tccaacattg taactttatc attaggaacc atttgaattt
    31681 caactctcgt tcccttatca actattttct taaaataata tttgtcttct tcacctagag
    31741 ctacacctcc cgttaccttt tcattttcct ccgttttact catctgtcct acattgaggt
    31801 actccaattt taaatttcct tcaatagaat catacacatc ttttggattt gtatatatca
    31861 gcattgttct cttttttatt ggcacagagt ttaaaacttc cacaaaccgt tttacactaa
    31921 agaaaacaat ttttaaacct accggtgcag aaatctttaa aatagattgt cgtgttttat
    31981 cttctgagat gcgatcatta acaatgataa cttgctcaat atcatacttt tttagccacg
    32041 tagtgacaac ttgaccatgt accagacggt catcaatacg aacaaactct atagacataa
    32101 atcttcttcc tcctctacgt taagttgttg tttaacatta aacaaactat tttgagcatt
    32161 gtgaacaatt tcttctaaat tgatttttga atcataactt gatattaatt ccactaggag
    32221 agggatatta aaccctgtta caatatcaac tgaatccaaa tttaaaaacc gtgacaaagc
    32281 cacattatta ggacttcctc caatcaagtc agtcaaaacg ataacctctt gatttgagtc
    32341 taacagttca tccacttgat ttttaaaata atgctcaaac tctacaatat tctctccagg
    32401 catcaaacct aatgtcctaa ctctatcatt tgttgtctca ccaacaaaca tttctgcggt
    32461 catgagagct ccgctagcaa aattaccatg actggcaact aaaattcctc tattgaacat
    32521 tttctctttc aacaactact cctttcttaa ggataatatt agcataaagt gaagtttctc
    32581 ctgtagcaac aatagcataa gctttcttac tacgttcata aaagtcttct cttctaagat
    32641 aagtaatcgt tttaagatct gtaccatgac cttcaatcat ctgtctatag gtaccccata
    32701 tcttaggaat atcatcaccc gaaacaacgt tcataaactg aattgaacta tcgacgtaac
    32761 tatctaatgg cattaaatac agaatggaat ctaataattc tggaatattt acaccatcac
    32821 aacgaattag cttatttgca catgaggcag aaggataatt cgcgtcagct aatactattt
    32881 catctccatg tcccatttcc attaaagtct tcaataaatc tggagaaata tttttcggta
    32941 tatgttttaa cattaatatc ctccctattt tctctgaccg tatgttttaa atttttctgc
    33001 catcaattcc atctcctcat caggaagaac tactggctct ccaaaattct tagctaaaca
    33061 ataaattttt gcacaatatt caacttcttc aacaatatta aatgcattca ataaattttg
    33121 tgcacctgct aaaattccat gattcgctag taaaactgct ctacgacctt ccattgcttt
    33181 agctgcattc acagccaatt ctttcgtgcc atatgttgca tactcagcta cccgaacatc
    33241 tttccctgcc actgcaatca tataatgact cgctggaagt ggttctctga gacaagctaa
    33301 tactgttgca taagttgtat gagcatggat aattgcatcg atatcatcac gagtttgata
    33361 ttgaatcaaa tgcatatacc attcgctaga tggcaagcgt tctccctcta caacatttcc
    33421 attaatatcc atcactacaa tatcggattc tttgatttca aagaaatcaa tacccgacgg
    33481 ggtaattgcc atcaattgtt tttcacgatc gaaaacgctg agattcccac ctgttccttt
    33541 cgtcaaatct gtttctacta gcttcttacc atatttaatt aattcttgtt ttacatctga
    33601 catccttgtc ctcctcatat caaaacacta aatatttttc aattcaccaa ttatcccccc
    33661 ttcctgcaca aaagctaaga agggggaggg aggcaaattt acaaactctc aatcttttta
    33721 attcttttgg gagtaataac tctctaattg tagaaactcc tcaataacat ggtgagcctc
    33781 ttccatccct tttaattgtc ccatagctat gagctgcaca acaatattcc ccacagctgt
    33841 agcctcagtc aaacctgtaa gaacctcttt accagttcta tcagcaatca tttggttaaa
    33901 gtaactggct ctagcacctc ctccaatcac atatatcctc ttataaacct tatgagttag
    33961 ttcttctagt aactctatcg ctttcctata cgtttcagct aggctttcat aaacaatctt
    34021 aaatagttgt ccatctgtcc actctctagt ttcatgatga taagctagat attctgtcaa
    34081 agtcttgtgc atatcagatt ctgttgcaaa ttcagttgat tcagtatcaa tcagaggaag
    34141 attttctttt tctttctcca ccattgtcct aatatcatca aaagaatagg ctttccctct
    34201 tcgttcaaat gaacgtctta gttcctctat gatccacaac cctgtacaat tcttcagaaa
    34261 tgtaatcact ccatctttac cgacttcatt tgtaaatcca taactgaagg attcggtagt
    34321 aagaatcggt gaagtaagtt ccactccaac caaagaccaa gtacctgatg aaataaataa
    34381 actaccttct gtcttaggta ctgagacaat cgcgcttgct gtatcatgac tacaaacatt
    34441 cacaacagga atatcgccta aaccatactc ctcttttatc cttccaagaa catttccctc
    34501 tgaaacaatt tcaggaagta aagatgaatc caattcaaat agttttaaga tattctgatt
    34561 ccaattttga ctcctaggat caaataattg agttgttgaa gcaatgcttt tttctgtagc
    34621 aaacttacct gtcaagagat aattaaacaa atctggcatt aaaagaatct tattggtctt
    34681 atagaaagag tcaggagatt cttgacgtgc cttaaagagt tgaaacaagg tatttatctc
    34741 cataatctga tttcctgtct ctgaatacag tttttctaat tcagtcattt cagatatttc
    34801 ctttaacact ccctttgttc tttcatcacg ataatgaaca ggttgtaata acagcttacc
    34861 ttcattatca atcagtccaa aatcaactcc ccatgtgtca ataccgatag ataaaatctt
    34921 gtaactagta ttagccaagc ggatactttc aagaatttta gctagtagaa agtcaatatc
    34981 ccaagataaa tgccctttta ctctaatagg tagattagaa aagcgattta tttcttccat
    35041 tactagttta ttttcagaaa ggtaaccaac gattgctctt ccagaagtcg cacctaaatc
    35101 tattgctaaa accgcttcca tttttcttct ctcttcgtcc ttgattaact ttattataat
    35161 ccccacgttt tattttttca atatgtgaac gcttacttga ataatgttca aatgttaacc
    35221 caatattcat aaaaataatt caaattcctc caatttgtgc tataatatag ttgaaatgat
    35281 aaattaggag gagcttatga taaaagatga acgtgtactt gaattgattg aaattatcaa
    35341 aaagaaaaaa agaattgccg taaaagagct ggcagaaatc actttctcca gcacaagtac
    35401 cttacgtcgt gatttaattt tcttagaaaa tcaaggtctt atcaaaagaa agcacggata
    35461 cgtgaccctg tcctctatga acacaattga actttctcat caaatacgtg aaggagaaag
    35521 tactaggcaa aaaagactaa tcgctagtct cgctaaagac tttattcggt ctggtatgtg
    35581 tatctatcta gattctagta ctactgtcta cgaactctgt ccctatcttt ctgaacttga
    35641 taatttgatt atttttacaa atggtttaca tactgcacaa accctatctg aaactgttaa
    35701 agatagctcc aaaatcttta tcacatctgg cgaggtcaaa catcaatcct gttccgtggt
    35761 caactatgat aaggaaaatt ctttattaga tcattttaat atcgatttag cattttgttc
    35821 agcaagaggt attgatgacc aatatgttta tgaagcttct ctcagccaag ctatttcaaa
    35881 aaagaatatt attgacaaag cccatgaaac catcttactg attgatagtt ctaaatttta
    35941 caagactgga ttttttaaaa ttaatcccct ctccaaatac acaaccttta tttcagacac
    36001 cgtgccagat caaaaattat tagacgcagt cgaattattt gatggagaat gggtttctga
    36061 tattcaatga aaatcaaata ggaagctagt ctcagcttgc tcaaagtaca gatttgaaaa
    36121 ttgatcaagt cagctcgaaa cactgttttg aggttgtaga tagaactgat gaagtcagtc
    36181 acatatatac ggaaagacga agctgacatg atgtgaagag attttcgaag agtatcgttc
    36241 tgtctgctga ctgatttaca aatattcacc acatgacatt attttcttag caaccctaaa
    36301 aacagaggct ggacaaaaac tcaatttcag gagaaaatgg agtaaacctt cccacaataa
    36361 aacgcatagt atcaagtttt tgcacacctg atattatgcg tttttctgat tttaaagatt
    36421 tttctcttag atctgatatt tcaagaatta agtgaccttg atgatctaaa tgtattgtgg
    36481 tatactattt ttgtcatcgg ttaccgatta cgttcctatg ggttcgtgag aggaggtgaa
    36541 actaatgagc cttatcatag agctcgctct tactattata gcggatgtta tagctggaat
    36601 tatcttgtat ttcgtctgca gatggctaga tagtaaggag tagaccgact gactagccta
    36661 taaacacccg ttaaatcgct aagatacgtc aaaaaagccc ttaactacgg ccatagttag
    36721 gggctttggt gttctaatga accttatcaa ttaactacat tctagcatat aatctacaat
    36781 agttcaagca ttaagtaagg ttgatgacct gaatgtagtg tgatatacta tttttgtcat
    36841 cggttaccga ttacgttcct tacggttcgt gagaggaggt gaaactaatg agccttatac
    36901 cagagcttgc tcttactatt atagcagatg ttatagctgg aattatcttg tatttcgtct
    36961 gcaaatggct agatggtaag aagtagaccg aatgactagc ctataaacac ccgttaaatc
    37021 gctaagatac gtcaaaaaag cccttaacta tggcactagt taggggcttt ggtgttctaa
    37081 tgaaccttat acactaacta cattctagca tataagccca gatatttcaa gagttttatt
    37141 tattgtttaa agttctgaaa ggtctataat gaagttagcc atctagtatc aaaaaaccga
    37201 ctagctctta tgaactagtc gatttctcat caatgcgcca acatttcttg ggcgatttct
    37261 tggccagata ggttatctgg gtagtaggtt ggccagttgt ccatttcttc aaagagggct
    37321 tcttggcttg tgcctccaaa gaagatatgg aaatgttctg ccttaactgg ggcaacattg
    37381 tggtcactaa actgaacata cttgaattgt ccagcgtcag catctgtggc ttcaaagagg
    37441 aaacgcacgc cacgattgcc tttcttgtaa gtcaaaattt tcttaccgac atacttgtaa
    37501 gtgtatttct tgctttgtcc accttgaaca aattccatag tattatcagt aatgttaatc
    37561 ttagtcacat ctgtatgata gccttttgta tagtaagcct tgtactcagc ctgggtcatc
    37621 ttaccagtca acttagcctt gtagtcaaag acttggtcaa acgtgccgtc ttcaaggaaa
    37681 ggataaactg attgccagtt acctgcatag tcactcaagg tgcggtcctt gacagctgca
    37741 tcctcgaagt aaccattttg gactgtcttg gtatcctctg ccttttcagg ttcaattgct
    37801 gggccttctt ggtctgttgt ttgtttcaaa gccttgaggt ttttctccat cacggaaatg
    37861 tagttttctc cagccttggt gtcctcttct gtcagacttt ctaaaggatt gaggacatca
    37921 gttttgacac ctgcttcttt tgaaagtgtg ttagcaaggg cttgtgaggc attttcttca
    37981 aaatagatat aggcgatttt atttttcttg acatactctg tcaattctgc caagcgagca
    38041 gctgatggct ctgcatctgg agaaagtcct gagattgcga cttgtttgag tccatagtcc
    38101 aaggcaagat agttaaaggc tgcgtgttga gtcacaaagc tcttttgttt tgcttgagac
    38161 aaaccttctg cgtaagcctt atccaaggct tgcaattttt cgatataggc agctgcattc
    38221 ttctcaaagg tctctttttt atcaggataa tctgctgaca agctgtcgcg gatgtgctct
    38281 actagtttaa tggcacgaac tggtgataac caaacatggg ggtcaaactc atggtgatga
    38341 ccttcttctc catggtcatg gtctccctct tcttcctcgc cacctggcaa gagcaacata
    38401 tcgcctgtcg ccttgatggt tttcactttt ttcttatcca aggtatctag caatttaggt
    38461 acccatgttt ccatgttttc attttcataa acgaaggtat ctgcatcttg gattttggca
    38521 actgccttgg cagatggttc gtattcatga ggttctgtcc cagcaccgat taggagttct
    38581 acattagccg tatctcctgc gacttgcttg gtaaattcat agacagggta aaaggttgtc
    38641 acgatattga gtttaccatc tgcctgtttt tgattggaac aagccactaa aaacaaggca
    38701 catagactgg ctagtaataa gctaattttt ttcacgttcg tctcctattt gataaaacgt
    38761 cttactaaac tgattagtat aaagacagtt acaaaaataa tggtaatact tgcacttgca
    38821 ggtgtttctg catagtagga aatgtaaagt cctgctacca ttcccaaaaa gccaatcgca
    38881 ctggcaagca gcataaccga tttaaagttt ttccccagac gcagggcaat actagctggc
    38941 aagaccataa tggtcgatac cagaagagct cctgctgcag gaatcataag ggcaatagcc
    39001 acccctgtca ccatgttaaa aagaatggac atggtacgaa ctggcaagcc atccacaaag
    39061 gccgtatctt cgtcaaaagt taagatatac ataggacgaa gaaagagaaa ggtcaaaatc
    39121 aaaacaaccg ccgcaatgac aaagagggaa atgacctgtt cttcactgat agtcacgatc
    39181 gaaccaaaga gatattggtc caaactcatt gaactcgagc ttttaccctt gctcatgaca
    39241 atcagagaaa cagccagacc tgttgacatg aggatagctg tcccgatttc cataaagctc
    39301 ttgtaaaccg tacggagata ctccagaaag accgccgcaa tcaagacaat ggcaatagta
    39361 gaaacagttg gagaaatccc caaaaccaga ccaaaggcta cacctgaaag tgagacgtgg
    39421 ctaagggtat cactcatcaa actctgacga cgcaagatga ggaaggttcc caataccggt
    39481 gagaaaagac tcatagcaat aaccgccaaa aaggcgcgtt gtataaagtc gtaagataat
    39541 aaactaagca tggcccacct cctggccatt ctcatgaaca ttgaaacaac gccatggcga
    39601 gtcttggtta cggactagat gaatattgcg atccgcataa tccttaactt cttcagggtc
    39661 atgggtaatc atcaaaacag ccttgccatg atgatgggcg ctgtggtgca tgagttcgta
    39721 aaattcattt ttacttcctg catccatccc cgttgtcggc tcgtctagga taaacacatc
    39781 agggtcagaa gcaaacatac gcgcaattac cgctcgctgc ttttgtcccc cagatagaga
    39841 ccccaagcgt ttgtctcgat gttcccacat gccaactgag tccagactag ccttgatatg
    39901 ctcctcatca tgagcattca aacgacggaa ccagcctttt ctcggatagc gacccgactt
    39961 gacaaattca tagaccgtac ttggaaaacc agcattaaaa ctggcaattt gttgaggaag
    40021 ataggctatt ctcaatttct taccttgcgt atttgtcttt gaaatagcca cctttccaat
    40081 gcgtggttgc agaattccaa gactagcctt gatgagcgtc gtcttagccg ctccattttc
    40141 cccagtcaag gtaacaaatt ccccactatc aacacaataa ttgatatgtt caagaacagg
    40201 ctccttatca taatagaagg acaaatcctc taccgtaata tatctcatta tttgatttct
    40261 cctactaaag cagtcaaaaa ccgctgaatc actttttgtt catttggagt aaactgagtc
    40321 gccacttgtt cataggttaa aagtgtatgc tcatggtgat ggtggtgctc ctcagcgatt
    40381 ggacgagcca agtcagtcaa ctgataaaaa atcacacgcg catctttaga atctttagat
    40441 gtttccaaca tcccttcctt gaccaaagac ttaatggcct tggtaactgc cgcctgactg
    40501 acattgagac gacgggccaa ttctgaattt gttaaagatt cctctgacaa gagcataagg
    40561 atatgctcct gagtattggt cagggccacc tcgctagtgc aatgacctat taggatttca
    40621 tgctgatttt ccgcctgcaa aatcacctca ttcaaaaaag cattgatatc ctttgctagc
    40681 tgtctcatat ctgactcctt tccttttaga cttctctttt ttaagagaaa aatactattc
    40741 tttgacattt tgtttaccag ttaattatat cacaagcaaa aaaagagtca agaaaaaacg
    40801 tgaaaactag tttcattctt gaactcttct atattatatt atctattgaa attctttgac
    40861 atctccatca taagtcgccc aatctttgct gaaaaagcgc tcattcagat ggtaagtcgg
    40921 agctggtgtg ggattggata ggaaaggatc aactgccttg tcaaaagcca accaacccaa
    40981 ccaaccaagg tgaatggtgt ccttcataaa gaaaggctcc ccgccgtcct tagaaaaatc
    41041 tgctatattg gtaaaacctt gactttctaa ctggtagcga atcttctgca ccgtttgttg
    41101 gtacatatcc tctcgtagac cagcatagtt catccatttt ttattaacag gtggaatgat
    41161 aaaaatcggg tttaccttag atttagaaaa ctgtgttaaa accaactgca agtcattata
    41221 ctctggcgac ttgagatagg taaagctttt ctgagaatcc tttaatttct tcaaatcctt
    41281 cttgatctgc tcattataga aataattttc cattcccatc tcattattgg aagtattttt
    41341 ttcagcatct gctttgacaa catcttctat tgcctgataa gaaaactggt ctggcaagat
    41401 ttttaaatac ttagctacat gcttatcgta gttaacatag cctctaaccg aaaactgacc
    41461 aaaaaaggaa gcttggcgtt cattaaaacg agccaataat tcaatcattt cattgtctgc
    41521 tgtcgacaat tcttctttac ttgccaactt ctgaaccagg tccttcatag ctacgtttgg
    41581 gaactgttgc agtaagcgag tcgctgcata ttgactagcc tgatccccag attgatgttt
    41641 cagaaaacta gtcaactggt ctccattaaa atactgctgg aaggctgctg gatcatagcc
    41701 atttttactg aaccactgag gtgagataac atacacaact tgtttattct ccagctgtgg
    41761 taacatctgt tgcattccaa aatattggtt aagcgatgca gctcccccct gtcctaaaag
    41821 ataaggacgg taggaacgat tgtatttctc agctaatacc gcaggatgag caccgtcaaa
    41881 acgaagccat tcactagagc caaagaaggg aacaaaacgc acatttggat cagatagtgc
    41941 tctgactttt tgacttcgct ccttaaaact atcgatagta gtagccactg ctgaacgctt
    42001 ttcagctcct agattatgat gcatctcagt aggataaaag aaaatgagca gaaaaaccaa
    42061 caaaccagcg atcaagaccg gtccgaagat catccataag cgtttaagca ttttgtagct
    42121 ccacaatacc agctatgatt ttattagctg tattccagtc gtcacgacca aactctgtta
    42181 cagggacacg aatgtcaaaa cggttctcaa tctccacaat caactcaacc gttcccatac
    42241 tatccaagac acctgcatca aaaagatctt catccatcat gtcagaaaca tcttccataa
    42301 acaactcatc aataatttca ataacttctg atttgatatc catattttat ttccttttat
    42361 tttttaaacc atagattatt caagaatcca gaaaagatta agaatgacaa catgacaaca
    42421 tggaaagtga caaccatgcc aagcaactga atccagcgat tctcaggtag ggcagccttc
    42481 cctgcttttt tccgttcctt attgagcgtt tttttcttgc gaacccaggc atcattgatg
    42541 accaagccta gtccatgaaa gagtccatag gcgatatagt accaggtcac accatgccaa
    42601 aatcccataa tcagcatatt tacaatgtag gccatgcttg aggttacatt acgattttta
    42661 aagactttct ttctggttaa caccatcacc attcgcataa agacaaagtc acggaaccag
    42721 aaggacagac tcatatgcca gcgattccaa aactccttta aatcccttga taaaaagggc
    42781 ttgttaaagt tgatagggct acggattccc atcaagtttg agatggccaa agcaaacata
    42841 gaataacctg caaagtcaaa gaagagttcc agaccaaaag tatacataac tgccaaggca
    42901 tagagattaa agaagccacc tgactgcaag gctaaattct tcagaggagg tagtaaggtc
    42961 tctcctaaaa catgagctag gataaactta tacaaaaagc cccacatgat atagcggaca
    43021 gattcatcca gcatatccat caactcatct cgctcaggaa tagcctgata attttcatta
    43081 aatcgcttaa agcgatcgat tggaccactc gagaaagttg gcatgaagag aaggaaacgg
    43141 aggaattccc agagggtaaa atccttaatc actccatctc tcagctcgat gacaattcca
    43201 accgaacgaa aggtcaggta agaaattccc aagaacccaa gcaaagactg cgttccattg
    43261 atagctggtt gcaccttgac aaagataatc ggaagtaggg acagaaaact aactaagtag
    43321 aagacccact tgccatcctt gctttttcga taatgcttgt agaaaagcag gagcaatatt
    43381 tcccagcaaa ggtaaatacc caaggcagct agttgattgg tctttccacc caccaacatg
    43441 gtgacaataa agaagagact taccaacact tcataccagg caaagcgttt cttgaaaaag
    43501 agacctataa agatgggcaa ggttgcagca atcacataaa caaaatactg aggattgcca
    43561 tatggctcta aatgaggaag ctgttgaaaa aactccatca tctcttattc acctcgttaa
    43621 tcaatccttt gatgtcaatc tttccatttg gagttagtgg caaactgtct cggtaaagga
    43681 atttagatgg catcatatag gacatcatga tgtctgtcag gtcttccttg atggccttgg
    43741 taatatcgat atctcgctca aactgctcac gaacaccgtc ttttaagatg acataagcca
    43801 atagattttg taccttgtgg tccttgttat agcgcggtac tgcgacagca gattcgataa
    43861 agcgagactt gttgaggttt tgagagacat cttctaactc aatgcggtaa ccgttaaact
    43921 taatctggaa gtccatgcgt ccgccgtaga gaagcaagcc ctcatctgtc atggttccca
    43981 catcgcctgt gtgataggct ggcagatctt caaactcaaa gaaggcttct gctgtttttt
    44041 caggattgtt catataacct tttgaaacag ctggcccaga aacaatgatt tctccctgct
    44101 caccatttgg cagtttattt ccttcctcgt caatgataaa ggttggagaa tcagccttgg
    44161 tatagccgat tggtaggcgt ttgagagtcg ctaacatctc gtctgtcacg gcaactgctg
    44221 acagagctac tgtcgcttct gttgggccgt aagcattgat gatacgggca tttgggaaac
    44281 gctcgcgcag tttttgagct gttttgaccg tcaattcttc accatcaaag tagaaatgcg
    44341 tgattccagg cattttctca ctgttgaagt attcagacaa catggccata tctgcaaagg
    44401 atggtgttga tgtccagata gcgattggca atgaaaagat agccgcaaag agttgcttaa
    44461 agtcctgagt gatgactgaa ggaagagtga aaagcgtacc accaagtgcc aaggtcggtg
    44521 cccaatacat gacagacaag tcaaaagaat aaggtggctg tgccagcatt tgcggacgac
    44581 tcggtgtcgc aaattcctta tccgtaatca tccagtttgt aaagctgagg agattatcat
    44641 gtgaaatctg cactccctta ggcttaccag tcgtaccaga agtaaagata atgtagtaat
    44701 tatcatctcc cttgactgga tgcgtgattt catagttatt cccttgggca aaggcttctt
    44761 gaacctgagc tagatttatc attggtgtag aaacctgctc caagggaaag gctgaaatgg
    44821 caataatcaa gcttggctct gctacttcta aaatagctga aactcgctcc aaggccgaat
    44881 ggctatcaat tggaatgtag gcatgacctg acttagtcag cgctacaaag gttgccaaca
    44941 tttcatattc ttggccacca aaaacaacca caggagactt ctcaggcaag cctagttggt
    45001 caatgactgc agccaaacta tccgaatcag cctttaaatc gccataagtg tgttcctgcc
    45061 ccaaaacatt atagacagga tagctaggct gtgtctgagc aaaatgctca atggtttcaa
    45121 tcatatctgc tattggttta tttgacacaa tagggattct ccttcaagtt aaaattcatt
    45181 atagataaag cttccttgac cctgaccaag atagctaaag aagtaaagca gccctagaaa
    45241 gataagaaaa tacaaggctg tccgaccaag aaagaggtac aattcttttc tctgtttcat
    45301 caagaaaaac cattcatttc tgtaattttt cgctaaaata agagtgattc ttactagctt
    45361 atttttctac cattgtacca ctttatatag tatcttttca attgtttacc gtatgtttcc
    45421 aatagatttc agcttatttt aaggattata cagtttttct atgtatattt tcaaatagag
    45481 tgatcctgct tcaaaactcc atttcaggag acaatgaagt aaatcttccc ataataaaac
    45541 acacaatatc aagttttttc aacacctgat actatgcgct tttctgattt ttaaagactt
    45601 tttaaccact ctctcattta aaataatctc gtctgatata aattaaaata gcttctatca
    45661 tcagacaaat ggctgatagc caaaaactga tgctaatacc aaaactctca gtaatatagc
    45721 tcattagcaa aacaaatact gaaaatgcta atgtagaaat cacttcaaga acggaataga
    45781 cattaactaa atgattttcc tctactgttt cctgaagaaa tacactttca ggaacttctt
    45841 ttagttgcga taacatacca actaaagctg aaaataataa aaacatctgt gcgtttggaa
    45901 aatatagaat agtcagtgtc actatttcca tagctacaag aggaaaaaga atactttccc
    45961 atttagcagc aaggaacttt tcagatagcc taaaagcaat taagccacta attataatac
    46021 caatagagta tgctgtatta gaatatcccc agtaactttc cgttttattt aataactccg
    46081 ttacaaaaac aagtataatg gaagaaaccc aaatcgtatt tgaaaaaatt tccaataaat
    46141 ttgctgatac aaaaagtctt aatctaggat ttctagcaac taacttccaa cctttgagca
    46201 aaatttcaag attagtttct gactctaaca cctccacttc agcgttagga agaaataaca
    46261 tcagaaagct agaaatgata tacaagacta aattgataca cgtggtaggt aacagaccaa
    46321 ttgttgcaaa caagagtcca cctaatcccc aacctatcaa ttgaacagct tcaccagtca
    46381 ttgataaggc tgaattagcc ttacccaaat cggtcgcata gcgtggcaca atagcatagg
    46441 aaacgggtgc tgcaaaacca tctagtatgg aaattgcaac aacaaataga taggtcacca
    46501 aaggcgctac ggattgcatt acggtaaaca ttcctaccag tatcgccaat aatatagtct
    46561 ttccaaattg agataaagat aaaaccctat ttagcgctaa ccttttagta accaacggaa
    46621 ctaaaagact cgcaacaaaa gaggatattc ctattaagat aggaactagt gatgtggcaa
    46681 ttactgattt tgaaataatg tatatgttag caatgattgt tactctaaag aaaatatctg
    46741 ctaaatttgc aaataattga gagactaaca acttgacaaa tgaattagac atgtagcgct
    46801 ccccctttag ttacaaactt tggaattaaa tttgattttt aatattttag cataaaatag
    46861 cagaaaacaa aagtgaggtt ttttacatga aaaaacaaaa actattgcct ttattattcc
    46921 taattttagg aggaattatg attatcgttg ttggctagta ctaagaagtt agttagttag
    46981 tagaataatt acatcttcaa tcgaaaaaga gactggaaaa agtcttaaaa atcagaaaaa
    47041 cgctcaaatc ctttggcgct ctaagctttt ctaatgatag atttagatag tcaaaaaaat
    47101 atctgaaaag ttcccaggat cgtcgtctca gcatcaaaaa tacgtgaaat ttgcataatt
    47161 aaaataaatt tcaggggagt
//
LOCUS       DAVFER010000015        45601 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1105170250
            SAMEA2167659-rid19724873.denovo.015, whole genome shotgun sequence.
ACCESSION   DAVFER010000015 DAVFER010000000
VERSION     DAVFER010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2167659
            Sequence Read Archive: ERR388902
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 45601)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 45601)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928716.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928716.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 04:07:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,118
            CDSs (total)                      :: 2,073
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 120
            CDSs (without protein)            :: 120
            Pseudo Genes (ambiguous residues) :: 0 of 120
            Pseudo Genes (frameshifted)       :: 67 of 120
            Pseudo Genes (incomplete)         :: 47 of 120
            Pseudo Genes (internal stop)      :: 34 of 120
            Pseudo Genes (multiple problems)  :: 23 of 120
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..45601
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2167659-rid19724873.denovo.015"
                     /strain="1105170250"
                     /db_xref="taxon:1313"
     gene            166..462
                     /locus_tag="VU534_000842"
     CDS             166..462
                     /locus_tag="VU534_000842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000380708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
                     /protein_id="HEU1513454.1"
                     /translation="MDTPDENGYVADDYRITYLEAHIKAMRDAIYQDGVDLLGYTTWG
                     CIDPVSAGTGEMNKRYGFIYVDRDNVGNGALKRSKKKSFYWYKDVIYSNGASIG"
     gene            583..1527
                     /gene="manA"
                     /locus_tag="VU534_000843"
     CDS             583..1527
                     /gene="manA"
                     /locus_tag="VU534_000843"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HEU1513455.1"
                     /translation="MSEPLFLQSVMQEKIWGGAKLRDEFGYDIPSEKIGEYWAISAHP
                     NGVSKVANGRYEGTDLATLYAEHRELFGNRPEPVFPLLTKILDANDWLSVQVHPDDAY
                     GLEHEGELGKTECWYIIAADEGSEIIYGHNAKSKEELRQQIEDKNWDDLLTKVPVKAG
                     DFFYVPSGTMHAIGAGILILETQQSSDTTYRVYDFDRKDDKGNLRELHLEKSIDVLNI
                     GEPANSRPVTVKADDLRSTLLVSNDFFAVYKWEITGKVDFEKTADYSLLSVLAGQGQL
                     TVDGKNYPIQKGSHFILPSDVEAWTLEGQGLELIVSHP"
     gene            complement(1567..2914)
                     /locus_tag="VU534_000844"
                     /pseudo
     CDS             complement(1567..2914)
                     /locus_tag="VU534_000844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466604.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-dependent transporter"
     gene            3142..3882
                     /locus_tag="VU534_000845"
     CDS             3142..3882
                     /locus_tag="VU534_000845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000274781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HEU1513456.1"
                     /translation="MYHIKEAAQLSGVSVKTLHHYDKIGLLVPLKSENGYRTYSQEDL
                     ERLQVILYYKYLGFSLEKIAELLKEERTDLLPHLTRQLDYLTRERQHLDTLISTLQKT
                     IQEQKGERKMTIEEKFTGFSYQDNQKYHQEAVEKYGQEVMGQALERQKGHEDEATAAF
                     NQVFQTLAQNLQVGLPATATENQEQAAKLLQAIRTYGFDCSIEVFGHIGKGYVYNPEF
                     KENIDKFGSETAQYTSDAIAVYVQTNAE"
     gene            complement(3911..4366)
                     /locus_tag="VU534_000846"
     CDS             complement(3911..4366)
                     /locus_tag="VU534_000846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001081770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HEU1513457.1"
                     /translation="MNRREAVEFVNMCMIKNGDKVLVQDRVNPDWSGITFPGGHVERG
                     ESFVDAVIREVKEETGLIISKPQLCGIKNWYDDKDYRYVVLFYKTEHFTGELQSSDEG
                     KVWWEDFENLSHLKLATDDMSDMLRVFLEEDLSEFFYYKNGDDWLYDLK"
     gene            complement(4386..5561)
                     /locus_tag="VU534_000847"
     CDS             complement(4386..5561)
                     /locus_tag="VU534_000847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HEU1513458.1"
                     /translation="MKHFDTIVIGGGPAGMMATISSSFYGQKTLLIEKNRKLGKKLAG
                     TGGGRCNVTNNGSLDNLLAGIPGNGRFLYSVFSQFDNHDIINFFTENGVKLKVEDHGR
                     VFPASDKSRTIIEALEKKITELGGQVATQIEIVSVKKVDDQFVLKSADQTFTCEKLIV
                     TTGGKSYPSTGSTGFGHEIARHFKHTITDLEAAESPLLTDFPHKALQGISLDDVTLSY
                     GKHVITHDLLFTHFGLSGPAALRMSSFVKGGEVLSLDVLPQLSEKDLVTFLEENREKS
                     LKNALKTLLPERLAEFFVQGYPEKVKQLTEKEREQLVQSIKELKIPVTGKMSLAKSFV
                     TKGGVSLKEINPKTLESKLVPGLHFAGEVMDINAHTGGFNITSALCTGWVAGSLHYD"
     gene            complement(5620..6465)
                     /locus_tag="VU534_000848"
     CDS             complement(5620..6465)
                     /locus_tag="VU534_000848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEU1513459.1"
                     /translation="MTWKIIADSGCDYRQLPTPAINTTFVSVPLTIQVADQVFVDDAS
                     LDIDQMMETMYATAEASKSACPSPDDYLRAFEGAKNIFLVTITGTLSGSHNSAQLAKN
                     IYLEDHPDTKIHVIDSLSAGGEVDLLVEKLNDLIDQGLSFEEVVEAITAYQEKTKLLF
                     VLAKVDNLVKNGRLSKLIGTVVGLLNIRMVGKASETGTLELLQKARGSKKSVQAAYDE
                     LVKAGYAGGRIVMAQRNNEKCCQQLSERIRETFPQADIKILPTSGLCSFYAEEGGLLM
                     GYEID"
     gene            6590..7147
                     /locus_tag="VU534_000849"
     CDS             6590..7147
                     /locus_tag="VU534_000849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEU1513460.1"
                     /translation="MSERRISEKSLENLRKSNQESNLLTREAIETALLQLLEKKELTK
                     ISISELVKRAGVSRAAFYRNYDSKEEILESVFKRTVHNIMEQLHHYDLKTDLYLVWVH
                     LFREARKEARVIQLALDYHLEKIFVQAMQEFLEKYHGKSKGVSSYLHSFWSSAIVSVL
                     LKWIKDGMKVPAEKIADLGLPFFKK"
     gene            7166..7633
                     /locus_tag="VU534_000850"
     CDS             7166..7633
                     /locus_tag="VU534_000850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000138511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine/deoxycytidylate deaminase family
                     protein"
                     /protein_id="HEU1513461.1"
                     /translation="MTEKRLAWDEYFAAQALLIANRSTCKRAKVGAILVKDNKVISTG
                     YNGSVSGTEHCIDHECLVIEGHCVRTLHAEVNAILQGAERGVPKGFTAYVTHFPCLNC
                     TKQLLQVGCKRVVYINQYRMDDYAQYLYQEKGTELTHLPLETVQTALKEADLM"
     gene            7722..8351
                     /gene="upp"
                     /locus_tag="VU534_000851"
     CDS             7722..8351
                     /gene="upp"
                     /locus_tag="VU534_000851"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002883819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HEU1513462.1"
                     /translation="MGKIEVINHPLIQHKLSILRRTDTSTKAFRELVDEIAMLMGYEV
                     LRDLPLEDVEIETPITKTVQKQLAGKKLAIVPILRAGIGMVDGLLNLVPAAKVGHIGM
                     YRDEETLQPVEYLVKLPEDIDQRQIFVVDPMLATGGSAILAVDSLKKRGASNIKFVCL
                     VSAPEGVKALQEAHPDVEIFTAALDERLNEHGYIVPGLGDAGDRLFGTK"
     gene            8525..9115
                     /gene="clpP"
                     /locus_tag="VU534_000852"
     CDS             8525..9115
                     /gene="clpP"
                     /locus_tag="VU534_000852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease proteolytic subunit
                     ClpP"
                     /protein_id="HEU1513463.1"
                     /translation="MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSVIA
                     QLLFLDAQDSTKDIYLYVNTPGGSVSAGLAIVDTMNFIKADVQTIVMGMAASMGTVIA
                     SSGAKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRNTLEKILAENSGQ
                     SMEKVHADAERDNWMSAQETLEYGFIDEIMANNSLN"
     gene            9194..9442
                     /locus_tag="VU534_000853"
     CDS             9194..9442
                     /locus_tag="VU534_000853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbG family protein"
                     /protein_id="HEU1513464.1"
                     /translation="MFEKVNRSGLIIYLYYNRDAKKLQDYGDITYHSKKHRYLQLYVP
                     TQEVEQLVGRLSKEKFIKKVRVCHIQELETPFVGNLYR"
     gene            9543..10703
                     /locus_tag="VU534_000854"
     CDS             9543..10703
                     /locus_tag="VU534_000854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEU1513465.1"
                     /translation="MKKKFALSFVALASVALLAACGEVKSGAVNTAGNSVEEKTIKIG
                     FNFEESGSLAAYGTAEQKGAQLAVDEINAAGGIDGKQIEVVDKDNKSETAEAASVTTN
                     LVTQSKVSAVVGPATSGATAAAVANATKAGVPLISPSATQDGLTKGQDYLFIGTFQDS
                     FQGKIISNYVSEKLNAKKVVLYTDNASDYAKGIAKSFRESYKGEIVADETFVAGDTDF
                     QAALTKMKGKDFDAIVVPGYYNEAGKIVNQARGMGIDKPIVGGDGFNGEEFVQQATAE
                     KASNIYFISGFSTTVEVSAKAKAFLDAYRAKYNEEPSTFAALAYDSVHLVANAAKGAK
                     NSGEIKNNLAKTKDFEGVTGQTSFDADHNTVKTAYMMTMNNGKVEAAEVVKP"
     gene            10971..11840
                     /locus_tag="VU534_000855"
     CDS             10971..11840
                     /locus_tag="VU534_000855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HEU1513466.1"
                     /translation="MLQQLVNGLILGSVYALLALGYTMVYGIIKLINFAHGDIYMMGA
                     FIGYFLINSFQMNFFVALIVAMLATAILGVVIEFLAYRPLRHSTRIAVLITAIGVSFL
                     LEYGMVYLVGANTRAFPQAIQTVRYDLGPISLTNVQLMILAISLILMILLQVIVQKTK
                     MGKAMRAVSVDSDAAQLMGINVNRTISFTFALGSALAGAAGVLIALYYNSLEPLMGVT
                     PGLKSFVAAVLGGIGIIPGAALGGFVIGLLETFATAFGMSDFRDAIVYGILLLILIVR
                     PAGILGKNVKEKV"
     gene            11844..12800
                     /locus_tag="VU534_000856"
     CDS             11844..12800
                     /locus_tag="VU534_000856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HEU1513467.1"
                     /translation="MKENLKVNILWLLLLLAGYSLISVLVSVGVLNLFYVQILQQIGI
                     NIILAVGLNLIVGFSGQFSLGHAGFMAIGAYAAAIIGSKSPTYGAFFGAMLVGALLSG
                     AVALLVGIPTLRLKGDYLAVATLGVSEIIRIFIINGGSLTNGAAGILGIPNFTTWQMV
                     YFFVVITTIATLNFLRSPIGRSTLSVREDEIAAESVGVNTTKIKIIAFVFGAITASIA
                     GSLQAGFIGSVVPKDYTFINSINVLIIVVFGGLGSITGAIVSAIVLGILNMLLQDVAS
                     VRMIIYALALVLVMIFRPGGLLGTWELSLSRFFKKSKKEEQN"
     gene            12800..13564
                     /locus_tag="VU534_000857"
     CDS             12800..13564
                     /locus_tag="VU534_000857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002913097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU1513468.1"
                     /translation="MALLEVKQLTKHFGGLTAVGDVTLELNEGELVGLIGPNGAGKTT
                     LFNLLTGVYEPSEGTVTLDGHLLNGKSPYKIASLGLGRTFQNIRLFKDLTVLDNVLIA
                     FGNHHKQHVFTSFLRLPAFYKSEKELKAKALELLKIFDLDGDAETLAKNLSYGQQRRL
                     EIVRALATEPKILFLDEPAAGMNPQETAELTELIRRIKDEFKITIMLIEHDMNLVMEV
                     TERIYVLEYGRLIAQGTPDEIKTNKRVIEAYLGGEA"
     gene            13564..14274
                     /locus_tag="VU534_000858"
     CDS             13564..14274
                     /locus_tag="VU534_000858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000062217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU1513469.1"
                     /translation="MSMLKVENLSVHYGMIQAVRDVSFEVNEGEVVSLIGANGAGKTT
                     ILRTLSGLVRPSSGKIEFLGQEIQKMPAQKIVASGLSQVPEGRHVFPGLTVMENLEMG
                     AFLKKNREENQANLKKVFSRFPRLEERKNQDAATLSGGEQQMLAMGRALMSTPKLLLL
                     DEPSMGLAPIFIQEIFDIIQDIQKQGTTVLLIEQNANKALAISDRGYVLETGRIVLSG
                     TGKELASSEEVRKAYLGG"
     gene            14582..15238
                     /locus_tag="VU534_000859"
     CDS             14582..15238
                     /locus_tag="VU534_000859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEU1513470.1"
                     /translation="MAVKDFMTRKVVYISPDTTVSHAADLMREQGLHRLPVIENDQLV
                     GLVTEGTIAQASPSKATSLSIYEMNYLLNKTKVKDVMIRDVVTVSGYASLEDATYLML
                     KNKISILPVVDNHQVYGVITDRDVFQAFLEIAGYGEEGIRVRFVTEDEVGVLGKIVSL
                     IVEENLNISHTVNIPRKDGKVIIEVQIDGSIDLPALKEKFEANGIQVEEIARTSAKVL
                     "
     gene            15346..16441
                     /gene="prfB"
                     /locus_tag="VU534_000860"
     CDS             join(15346..15417,15419..16441)
                     /gene="prfB"
                     /locus_tag="VU534_000860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511312.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HEU1513471.1"
                     /translation="MDISVIRQKIDANREKLASFRGSLDLEGLEEEIAILENKMTEPD
                     FWNDNIAAQKTSQELNELKNTYNTFHKMEELQDEVEILLDFLAEDESVHDELVAQLAE
                     LDKIMTSYEMTLLLSEPYDHNNAILEIHPGSGGTEAQDWGDMLLRMYTRYGNAKGFKV
                     EVLDYQAGDEAGIKSVTLSFEGPNAYGLLKSEMGVHRLVRISPFDSAKRRHTSFTSVE
                     VMPELDDTIEVEIREDDIKMDTFRSGGAGGQNVNKVSTGVRLTHIPTGIVVQSTVDRT
                     QYGNRDRAMKMLQAKLYQMEQDKKAAEVDSLKGEKKEITWGSQIRSYVFTPYTMVKDH
                     RTSFEVAQVDKVMDGDLDGFIDAYLKWRIS"
     gene            16459..17151
                     /gene="ftsE"
                     /locus_tag="VU534_000861"
     CDS             16459..17151
                     /gene="ftsE"
                     /locus_tag="VU534_000861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012130521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HEU1513472.1"
                     /translation="MSIIEMRDVVKKYDNGTTALRGVSVSVQPGEFAYIVGPSGAGKS
                     TFIRSLYREVKIDKGSLSVAGFNLVKIKKKDVPLLRRSVGVVFQDYKLLPKKTVYENI
                     AYAMEVIGENRRNIKRRVMEVLDLVGLKHKVRSFPNELSGGEQQRIAIARAIVNNPKV
                     LIADEPTGNLDPDNSWEIMNLLERINLQGTTILMATHNSQIVNTLRHRVIAIENGRVV
                     RDESKGEYGYDD"
     gene            17144..18070
                     /locus_tag="VU534_000862"
     CDS             17144..18070
                     /locus_tag="VU534_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU1513473.1"
                     /translation="MISRFFRHLFEALKSLKRNGWMTVAAVSSVMITLTLVAIFASVI
                     FNTAKLATDIENNVRVVVYIRKDVEDNSQTIEKEGQTVTNNDYHKVYDSLKNMSTVKS
                     VTFSSKEEQYEKLTEIMGDNWKIFEGDANPLYDAYIVEANTPNDVKTIAEDAKKIEGV
                     SEVQDGGANTERLFKLASFIRVWGLGIAALLIFIAVFLISNTIRITIISRSREIQIMR
                     LVGAKNSYIRGPFLLEGAFIGLLGAIAPSVLVFIVYQIVYQSVNKSLVGQNLSMISPD
                     LFSPLMIALLFVIGVFIGSLGSGISMRRFLKI"
     gene            18356..20536
                     /locus_tag="VU534_000863"
     CDS             18356..20536
                     /locus_tag="VU534_000863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000974069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEU1513474.1"
                     /translation="MMKDTFKNVLSFEFWQKFGKALMVVIAVMPAAGLMISIGKSIVM
                     INPTFAPLVITGGILEQIGWGVIGNLHILFALAIGGSWAKERAGGAFAAGLAFILINR
                     ITGTIFGVSGDMLKNPDAMVTTFFGGSIKVADYFISVLEAPALNMGVFVGIISGFVGA
                     TAYNKYYNFRKLPDALSFFNGKRFVPFVVILRSAIAAILLAAFWPVVQTGINNFGIWI
                     ANSQETAPILAPFLYGTLERLLLPFGLHHMLTIPMNYTALGGTYDILTGAAKGTQVFG
                     QDPLWLAWVTDLVNLKGTDASQYQHLLDTVHPARFKVGQMIGSFGILMGVIVAIYRNV
                     DADKKHKYKGMMIATALATFLTGVTEPIEYMFMFIATPMYLVYSLVQGAAFAMADVVN
                     LRMHSFGSIEFLTRTPIAISAGIGMDIVNFVWVTVLFAVIMYFIANFMIQKFNYATPG
                     RNGNYETAEGSEETSSEVKVAAGSQAVNIINLLGGRVNIVDVDACMTRLRVTVKDADK
                     VGNAEQWKAEGAMGLVMKGQGVQAIYGPKADILKSDIQDILDSGEIIPETLPSQMTEA
                     QQNTVHFKDLTEEVYSVADGQVVALEQVKDPVFAQKMMGDGFAVEPANGNIVSPVSGT
                     VSSIFPTKHAFGIVTEAGLEVLVHIGLDTVSLEGKPFTVHVAEGQKVAAGDLLVTADL
                     DAIRAAGRETSTVVVFTNGDAIKSVKLEKTGSLAAKTAVAKVEL"
     gene            20588..21403
                     /locus_tag="VU534_000864"
     CDS             20588..21403
                     /locus_tag="VU534_000864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HEU1513475.1"
                     /translation="MKFLTLNTHSWMEKEAEEKFQILLEDILEKDYDLICFQEINQEM
                     TSSEVEVNDLYQALPAAEPIHQDHYVRLLVEKLSEQGKNYYWTWAYNHIGYNRYHEGV
                     AILSKTPIEAREILVSDVDDPTDYHTRRVALAETVVDGKELAVASVHLSWWDKGFQEE
                     WARFEAVLKKLNKPLLLAGDFNNPAGQEGYQAILASPLGLQDAFEVAQEKSGSYTVPP
                     EIDGWKGNTEPLRIDYVFTTKELAVENLHVVFDGNKSPQVSDHYGLNAILNWK"
     gene            21543..22886
                     /locus_tag="VU534_000865"
     CDS             21543..22886
                     /locus_tag="VU534_000865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEU1513476.1"
                     /translation="MSFTKFQFKNYIREALKELKFTTPTEVQDKLIPIVLAGRDLVGE
                     SKTGSGKTHTFLLPIFQQLDEASDSVQAVITAPSRELATQIYQVARQISAHSDVEVRV
                     VNYVGGTDKARQIEKLASNQPHIVIGTPGRIYDLVKSGDLAIHKAKTFVVDEADMTLD
                     MGFLETVDKIAGSLPKDLQFMVFSATIPQKLQPFLKKYLSNPVMEKIKTKTVISDTID
                     NWLISTKGHDKNAQIYQLTQLMQPYLAMIFVNTKTRADELHSYLTAQGLKVAKIHGDI
                     APRERKRIMNQVQNLDFEYIVATDLAARGIDIEGVSHVINDAIPQDLSFFVHRVGRTG
                     RNGLPGTAITLYQPSDDSDIRELEKLGIKFSPKMVKDGEFQDTYDRDRRANREKKQDK
                     LDIEMIGLVKKKKKKVKPGYKKKIQWAVDEKRRKTKRAENRARGRAERKAKRQTF"
     gene            23101..24291
                     /locus_tag="VU534_000866"
     CDS             23101..24291
                     /locus_tag="VU534_000866"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HEU1513477.1"
                     /translation="MSERKLFTSESVSEGHPDKIADQISDAILDAILAKDPEAHVAAE
                     TAVYTGSVHVFGEISTNAYVDINRVVRDTIAEIGYTNTEYGFSAETVGVHPSLVEQSP
                     DIAQGVNEALEVRGNADQDPLDLIGAGDQGLMFGFAVDETEELMPLPIALSHKLVRRL
                     AELRKSGEISYLRPDAKSQVTVEYDENDRPVRVDTVVISTQHDPEATNEQIHQDVIDK
                     VIKEVIPSSYLDDKTKFFINPTGRFVIGGPQGDSGLTGRKIIVDTYGGYSRHGGGAFS
                     GKDATKVDRSASYAARYIAKNIVAADLAKKAEVQLAYAIGVAQPVSVRIDTFGTGTVA
                     ESQLEKAARQIFDLRPAGIIQMLDLKRPIYRQTSAYGHMGRTDIDLPWERLDKVDALK
                     EAVK"
     gene            24844..25779
                     /locus_tag="VU534_000867"
     CDS             24844..25779
                     /locus_tag="VU534_000867"
                     /EC_number="1.3.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate oxidase"
                     /protein_id="HEU1513478.1"
                     /translation="MVSTKTQIAGFEFDNCLMNAAGVACMTIEELEEVKNSAAGTFVT
                     KTATLDFRQGNPEPRYQDVPLGSINSMGLPNNGLDYYLDYLLDLQEKESNRTFFLSLV
                     GMSPEETHTILKKVQESDFRGLTELNLSCPNVPGKPQIAYDFETTDRILAEVFAYFTK
                     PLGIKLPPYFDIVHFDQAAAIFNKYPLKFVNCVNSIGNGLYIEDESVVIRPKNGFGGI
                     GGEYIKPTALANVHAFYQRLNPQIQIIGTGGVLTGRDAFEHILCGASMVQVGTTLHKE
                     GVSAFDRITNELKAIMVEKGYESLEDFRGKLRYID"
     gene            25813..26850
                     /locus_tag="VU534_000868"
     CDS             25813..26850
                     /locus_tag="VU534_000868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HEU1513479.1"
                     /translation="MLAIEESQKLTLSNLPSLSLFTGTDQGQFEVMKSQMLKQIGYDS
                     ADLNFAYFDMKEVVYKDVELELVSLPFFADEKIVILDYFMDITTAKKRFLTDDELKSF
                     EEYLDNPSPTTKLIIFAEGKLDSKRRLVKLLKRDAKAFDAVEVKEQELRQYFQKWSQK
                     QGLQFTNHSFENLLIKSGFQFSEIQKNLLFLQSYKANSVIEEEDIVNAIPKTLQDNIF
                     DLTQFILTKKMDQARDLVRDLTLQGEDEIKLIAVMLGQFRTFTQVKILAESGQTESQI
                     ASSLGSYLGRNPNPYQIKFALRDSRGLSLSFLKQAISYLIETDYQIKTGLYEKGFLFE
                     KALLQIASQVN"
     gene            27023..27628
                     /locus_tag="VU534_000869"
     CDS             27023..27628
                     /locus_tag="VU534_000869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HEU1513480.1"
                     /translation="MAIILPELPYAYDALEPYIDAETMHLHHDKHHQTYVNNANAALE
                     KHPEIGEDLEALLADVESIPADIRQALINNGGGHLNHALFWELMTPEKTAPSAELAAA
                     IDATFGSFEEFQAAFTAAATTRFGSGWAWLVVNKEGKLEVTSTANQDTPISEGKKPIL
                     GLDVWEHAYYVKYRNVRPDYIKAFFSVINWNKVDELYAAAK"
     gene            27784..28296
                     /locus_tag="VU534_000870"
     CDS             27784..28296
                     /locus_tag="VU534_000870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YutD family protein"
                     /protein_id="HEU1513481.1"
                     /translation="MRKEIAPELYNYNKFPGPEFHLHGDKVETEGIAFSLVENIKDAF
                     DVTTFNQRFSEVLTKFDYIVGDWSNEQLRLRGFYKDDRTEEKLEKISRLQDYLLEYCS
                     YGCAYFVLENEAPKRASFDKKMRKTEEETPSRKGKKPTQTKRKSNADKKNRRRQKDDK
                     GQRHFVIRQK"
     gene            28317..29402
                     /gene="rlmN"
                     /locus_tag="VU534_000871"
     CDS             28317..29402
                     /gene="rlmN"
                     /locus_tag="VU534_000871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000804770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HEU1513482.1"
                     /translation="MKPSIHSLVHQTMQEWVLEQGEKKFRADQIWEWLYRKRVQSFEE
                     MTNLSKDLIAKLNDQFVVNPLKQRIVQESADGTVKYLFELPDGMLIETVLMRQHYGLS
                     VCVTTQVGCNIGCTFCASGLIKKQRDLNNGEIVAQIMLVQKYFDERGQDERISHIVVM
                     GIGEPFDNYNNVLNFFRTINDDKGMAIGARHITVSTSGLAHKIRDFADEGVQVNLAVS
                     LHAPNNELRSSIMKINRAFPIEKLFAAIEYYIETTNRRVTFEYIMLNEVNDGVEQALE
                     LTELLKNIKKLSYVNLIPYNPVSEHDQYSRSPKECVLAFYDTLKKKGVNCVVRQEHGT
                     DIDAACGQLRSNTMKRDRQKAVAAVNP"
     gene            29402..29884
                     /locus_tag="VU534_000872"
     CDS             29402..29884
                     /locus_tag="VU534_000872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000976721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HEU1513483.1"
                     /translation="MMKKTYNHILVWGVIFYSICIVCFCFTPQEQSTVGVGTPGIQHL
                     GRLVFLLTPFNSLWKLGEVSDIGQLCWIFLQNILNVFLFFPLIFQLLYLFPNLRKTKK
                     VLLFSFLVSLGIECTQLILDFFFDFNRVFEIDDLWTNTLGGYLAWLLYKRLHKNKVRN
                     "
     gene            29886..31427
                     /locus_tag="VU534_000873"
     CDS             29886..31427
                     /locus_tag="VU534_000873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002918612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEU1513484.1"
                     /translation="MSILEVKNLSHGFGDRAIFEDVSFRLLKGEHIGLVGANGEGKST
                     FMSIVTGKMLPDEGKVEWSKYVTAGYLDQHSVLAERQSVRDVLRTAFDELFKAEARIN
                     DLYMKMAEDGADVDALMEEVGELQDRLESRDFYTLDAKIDEVARALGVMDFGMDTDVT
                     SLSGGQRTKVLLAKLLLEKPDILLLDEPTNYLDAEHIDWLKRYLQNYENAFVLISHDI
                     PFLNDVINIVYHVENQQLTRYSGDYYQFQEVYAMKKSQLEAAYERQQKEIADLKDFVA
                     RNKARVATRNMAMSRQKKLDKMDIIELQSEKPKPSFDFKPARTPGRFIFQAKNLQIGY
                     DRPLTKPLNLTFERNQKVAIIGANGIGKTTLLKSLLGIISPIAGEVERGDYLELGYFE
                     QEVEGGNRQTPLEAVWNAFPALNQAEVRAALARCGLTTKHIESQIQVLSGGEQAKVRF
                     CLLMNRENNVLVLDEPTNHLDVDAKDELKRALKEYRGSILMVCHEPDFYEGWIDQIWD
                     FNNLT"
     gene            complement(31483..32286)
                     /locus_tag="VU534_000874"
     CDS             complement(31483..32286)
                     /locus_tag="VU534_000874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000731914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HEU1513485.1"
                     /translation="MKKLATLLLLSTVALAGCSSVQRSLRGDDYVDSSLAAEESSKVA
                     AQSAKELNDALTNENANFPQLSKEVAEDEAEVIFHTSQGDIRIKLFPKLAPLAVENFL
                     THAKEGYYNGITFHRVIDGFMVQTGDPKGDGTGGQSIWHDKDKTKDKGTGFKNEITPY
                     LYNIRGALAMANTGQPNTNGSQFFINQNSTDTSSKLPTSKYPQKIIEAYKEGGNPSLD
                     GKHPVFGQVIDGMDVVDKIAKAEKDEKDKPTTAITIDSIEVVKDYDFKS"
     gene            complement(32370..32583)
                     /locus_tag="VU534_000875"
                     /pseudo
     CDS             complement(32370..32583)
                     /locus_tag="VU534_000875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864170.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(33062..33271)
                     /locus_tag="VU534_000876"
     CDS             complement(33062..33271)
                     /locus_tag="VU534_000876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000953868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1513486.1"
                     /translation="MLSVNTILEKFYKEHQVKPFISPERELDTWLLSPKPVPKRNMDL
                     LVDDSLAGDIILLWRIQFGTFTTET"
     gene            33441..33713
                     /gene="rpsP"
                     /locus_tag="VU534_000877"
     CDS             33441..33713
                     /gene="rpsP"
                     /locus_tag="VU534_000877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HEU1513487.1"
                     /translation="MAVKIRLTRMGSKKKPFYRINVADSRSPRDGRFIETVGTYNPLV
                     AENQVTLKEDRVLAWLANGAQPSDTVRNILSKEGVLKKFHDSKFSK"
     gene            33733..33972
                     /locus_tag="VU534_000878"
     CDS             33733..33972
                     /locus_tag="VU534_000878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HEU1513488.1"
                     /translation="MDTIENLIIAIVKPLISQPDALTIKIEDTPEFLEYHLNLDQSDV
                     GRVIGRKGRTISAIRTIVYSVPTEYKKVRIVIDEK"
     gene            34549..35337
                     /locus_tag="VU534_000879"
     CDS             34549..35337
                     /locus_tag="VU534_000879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000819180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEU1513489.1"
                     /translation="MKRFEVSTEIGSLSVTYQKQKKVLVCLNGAGLLPSYENFSLILE
                     KPPPTIGYLTIDFPNTGRSPIHDQAGKNLDNLADAVYEVLEELGISEYILCAHSWSGI
                     LACKLLEKPIKRQTLVAIEPTTKKVMFADFSENPYPEMEEQMRLIDECGPELYFKNLT
                     QATFSPETNKKIWELMQEKGLELENQDPEFQISGEITEEDFEDVSIEAHIPVFVFCQP
                     YREKEYRESEYWTSNTKLILGGNHHYLQWSESEKIAAIIRELLE"
     gene            35368..35886
                     /gene="rimM"
                     /locus_tag="VU534_000880"
     CDS             35368..35886
                     /gene="rimM"
                     /locus_tag="VU534_000880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HEU1513490.1"
                     /translation="MNYFNVGKIVNTQGLQGEMRVLSVTDFAEERFKKGAELVLFDEK
                     DQFVQTVTIASHRKQKNFDIIKFKDMYHINTIEKYKGYSLKVAEEDLNDLDDGEFYYH
                     EIIGLEVYEGDSLVGTIKEILQPGANDVWVVKRKGKRDLLLPYIPPVVLNVDIPSKRV
                     DVEILEGLDDED"
     gene            35876..36595
                     /gene="trmD"
                     /locus_tag="VU534_000881"
     CDS             35876..36595
                     /gene="trmD"
                     /locus_tag="VU534_000881"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HEU1513491.1"
                     /translation="MKIDILTLFPEMFSPLEHSIVGKAREKGLLDIQYHNFRENAEKA
                     RHVDDEPYGGGQGMLLRAQPIFDSFDAIEKKNPRVILLDPAGKQFDQAYAEDLAQEEE
                     LIFICGHYEGYDERIKTLVTDEISLGDYVLTGGELAAMTMIDATVRLIPEVIGKESSH
                     QDDSFSSGLLEYPQYTRPYDYRGMVVPDVLMSGHHEKIRQWRLYESLKKTYERRPDLL
                     EHYQLTVEEEKMLAEIKENKE"
     gene            36607..36945
                     /locus_tag="VU534_000882"
     CDS             36607..36945
                     /locus_tag="VU534_000882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001196050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1513492.1"
                     /translation="MQVIKRNGEIAEFNPDKIYQAILKAAQTVYVLTDDLRQNLAQVT
                     KKVVLDLQEAKVERATISMIQSMVEHRLLGAGYITIAEHYISYRLQRDLERSGYGDHI
                     AVHLHFEQIR"
     gene            complement(36976..37296)
                     /locus_tag="VU534_000883"
     CDS             complement(36976..37296)
                     /locus_tag="VU534_000883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001216095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1513493.1"
                     /translation="MRHKFQQVLNKIHDFLNGYDQPDQTETNSLTATIEEAIQKQTAV
                     HLILSETSFTGDIIKYDQQGQQIIVKNFSKNVSRIIRISDIQRLRFVPSTVQTAQKNR
                     FKKE"
     gene            37394..37609
                     /locus_tag="VU534_000884"
     CDS             37394..37609
                     /locus_tag="VU534_000884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000807422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbC family protein"
                     /protein_id="HEU1513494.1"
                     /translation="MAEFTFEIEEHLLTLSENEKGWTKEINRVSFNGAPAKFDIRAWS
                     PDHTKMGKGITLSNEEFQTMVDAFKGN"
     gene            complement(37815..38351)
                     /locus_tag="VU534_000885"
     CDS             complement(37815..38351)
                     /locus_tag="VU534_000885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000709035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HEU1513495.1"
                     /translation="MKKAHVYAIPAIGAALIAALAQISLPIGPVPFTLQNFAIGLIAT
                     VFRPREAVLSAGLYLLLGAIGLPVFAGGGAGFQALVGPTAGYLWFYLVYSGLTSSLTN
                     SKSGVVKIFLANLLGDALVFVGGILSLHFLAGMAFEKALAVGVLPFIIPDLGKLLAIS
                     FISRPLLQRLKNQAYFTN"
     gene            complement(38548..39894)
                     /gene="gor"
                     /locus_tag="VU534_000886"
     CDS             complement(38548..39894)
                     /gene="gor"
                     /locus_tag="VU534_000886"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HEU1513496.1"
                     /translation="MREYDIIAIGGGSGGIATMNRAGEHGAKAAVIEEKKLGGTCVNV
                     GCVPKKIMWYGAQIAETFHQFGEDYGFKTTDLNFDFATLRRNREAYIDRARSSYDGSF
                     KRNGVDLIEGHAEFVDSHTVSVNGELIRAKHIVIATGAHPSIPNIPGAELGGSSDDVF
                     AWEELPESIAILGAGYIAVELAGVLHTFGVKTDLFVRRDRPLRGFDSYIVEGLVKEME
                     RTNLPLHTHKVPVKLEKTTDGITIHFEDGTSHTASQVIWATGRRPNVKGLQLEKAGVT
                     LNERGFIQVDEYQNTVVEGIYALGDVTGEKELTPVAIKAGRTLSERLFNGKTTAKMDY
                     STIPTVVFSHPAIGTVGLTEEQAIKEYGQDQIKVYKSSFASMYSACTRNRQESRFKLI
                     TAGSEEKVVGLHGIGYGVDEMIQGFAVAIKMGATKADFDATVAIHPTASEEFVTMR"
     gene            40159..41358
                     /locus_tag="VU534_000887"
     CDS             40159..41358
                     /locus_tag="VU534_000887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HEU1513497.1"
                     /translation="MKKKNGKAKKWQLYAAIGAASVVVLGAGGILLFRQPSQTALKDE
                     PTHLVVAKEGSVASSVLLSGTVTAKNEQYVYFDASKGDLDEILVSVGDKVSEGQALVK
                     YSSSEAQAAYDSASRAVARADRHINELNQARNEAASAPAPQLPAPVGGEDATVQSPTP
                     VAGNSVASIDAQLGDARDARADAAAQLSKAQSQLDATTVLSTLEGTVVEVNSNVSKSP
                     TGASQVMVHIVSNENLQVKGELSEYNLANLSVGQEVSFTSKVYPDKKWTGKLSYISDY
                     PKNNGEAASPAAGNNTGSKYPYTIDVTGEVGDLKQGFSVNIEVKSKTKAILVPVSSLV
                     MDDSKNYVWIVDEQQKAKKVEVSLGNADAENQEITSGLTNGAKVISNPTSSLEEGKEV
                     KADEATN"
     gene            41342..42043
                     /locus_tag="VU534_000888"
     CDS             41342..42043
                     /locus_tag="VU534_000888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU1513498.1"
                     /translation="MKQLISLKNIFRSYRNGDQELQVLKNINLEVNEGEFVAIMGPSG
                     SGKSTLMNTIGMLDTPTSGEYYLEGQEVAGLGEKQLAKVRNQQIGFVFQQFFLLSKLN
                     ALQNVELPLIYAGVSSSKRRKLAEEYLDKVELTERSHHLPSELSGGQKQRVAIARALV
                     NNPSIILADEPTGALDTKTGNQIMQLLVDLNKEGKTIIMVTHEPEIAAYAKRQIVIRD
                     GVISSDSAQLGKEEN"
     gene            42045..43304
                     /locus_tag="VU534_000889"
     CDS             42045..43304
                     /locus_tag="VU534_000889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU1513499.1"
                     /translation="MQNLKFAFSSIMAHKMRSLLTMIGIIIGVSSVVVIMALGDSLSR
                     QVNKDMTKSQKNISVFFSPKKSKDGSFTQKQSAFTVSGKEEEVPVEPPKPQESWVQEA
                     AKLKGVDSYYVTNSTNAILTYQDKKVENANLTGGNRTYMDAVKNEIIAGRSLREQDFK
                     EFASVILLDEELSISLFESPQEAINKVVEVNGFSYRVIGVYTSPEAKRSKIYGFGGLP
                     ITTNISLAANFNVDEIANIVFRVNDTSLTPTLGPELARKMTELAGLQQGEYQVADESV
                     VFAEIQQSFSFMTTIISSIAGISLFVGGTGVMNIMLVSVTERTREIGLRKALGATRAN
                     ILIQFLIESMILTLLGGLIGLTIASGLTALAGLLLQGLIEGIEVGVSIPVALFSLAVS
                     ASVGMIFGVLPANKASKLDPIEALRYE"
     gene            43428..45425
                     /gene="metG"
                     /locus_tag="VU534_000890"
     CDS             43428..45425
                     /gene="metG"
                     /locus_tag="VU534_000890"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HEU1513500.1"
                     /translation="MSEKNFYITTPIYYPSGKLHIGSAYTTIACDVLARYKRLMGYDV
                     FYLTGLDEHGQKIQQKAEEAGITPQAYVDGMAVGVKELWQLLDISYDKFIRTTDDYHE
                     KVVAQVFERLLAQDDIYLGEYSGWYSVSDEEFFTESQLAEVFRDEAGNVTGGIAPSGH
                     EVEWVSEESYFLRLSKYQDRLVEFFKAHPEFITPDGRLNEMLRNFIEPGLEDLAVSRT
                     TFTWGVPVPSNPKHVVYVWIDALLNYATALGYAQDEHGNFDKFWNGTVFHMVGKDILR
                     FHSIYWPILLMMLDVKLPDRLIAHGWFVMKDGKMSKSKGNVVYPEMLVERYGLDPLRY
                     YLMRNLPVGSDGTFTPEDYVGRINYELANDLGNLLNRTVSMINKYFDGQIPAYVEGVT
                     EFDHVLAEVAEQSIADFHTHMEAVDYPRALEAVWTLISRTNKYIDETAPWVLAKDEAL
                     RDQLASVMSHLAASIRVVAHLIEPFMMETSRAVLTQLGLEEVSSLENLSLADFPADVT
                     VVAKGTPIFPRLNMEEEIAYIKEQMEGNKPAVEKEWNPDEVELKLNKDEIKFEDFDKV
                     EIRVAEVKEVSKVEGSDKLLQFRLDAGDGEDRQILSGIAKYYPNEQELVGKKVQIVAN
                     LKPRKMMKKYVSQGMILSAEHDGKLTLLTVDPAVPNGSVIG"
BASE COUNT        13955 a         8457 c         9942 g        13247 t
ORIGIN      
        1 ttttactata gaacgatttg aaggcgttta tgatatttag ctgtacgaga gtcttttaaa
       61 agtgttttga tggtttggat ttcttcttta gttgatttca tatcactatt atataatgct
      121 ttttgatttt agtttagtat tatcgtagaa aatggactcg gtgctatgga tacaccggat
      181 gagaatggtt atgtagcaga tgactatcgg attacttact tagaggccca catcaaggcc
      241 atgcgagatg ccatttacca agacggggtt gacttgcttg gttatacgac ttggggctgt
      301 atcgatccgg tttcagctgg cacaggggaa atgaataagc gctatggctt tatctatgta
      361 gatcgagata atgtaggaaa cggagctctc aaacgtagca agaagaagtc cttctattgg
      421 tacaaggatg tcatttatag caatggtgca agcatcgggt agagcacatt tgtttactat
      481 ttttataaaa tcttctccct gctttataag atgtaaaaaa gagttcaatt cgaactcttt
      541 ttttgctata atgaggggag aaaaatcaga caggagatcg acatgtcaga accattattt
      601 ttacaatcag ttatgcaaga aaaaatctgg ggtggagcca agctacgtga tgagtttggc
      661 tacgacatcc caagtgaaaa aatcggagaa tattgggcca tctcagccca tccaaatgga
      721 gtctctaaag ttgccaatgg tcgttacgag ggaacagatc ttgctacttt gtatgcggaa
      781 caccgtgaat tatttggcaa tcgtccagaa cctgtatttc cacttttgac caagatcctc
      841 gatgccaacg actggctcag tgtccaagtt cacccagacg atgcttatgg actcgagcat
      901 gaaggcgaac tcggaaaaac agaatgctgg tacattatcg cagcggatga aggttcagag
      961 attatctacg gtcacaatgc caagtcaaaa gaagaactcc gccagcaaat cgaggacaag
     1021 aactgggatg acttgttgac caaagtccct gttaaggctg gagatttctt ctatgtacca
     1081 agcgggacta tgcacgctat cggggcgggt atcttaatcc ttgaaaccca gcagtctagc
     1141 gataccacct atcgcgtcta tgactttgac cgcaaggatg acaaaggcaa cttgcgtgaa
     1201 cttcatcttg aaaaatccat cgatgtcttg aacattggtg agccagcaaa tagccgtcct
     1261 gtaactgtta aagcagatga tttgcgttcc actctccttg tatctaatga tttcttcgca
     1321 gtttacaagt gggaaattac tggaaaagtt gactttgaaa agacagctga ctacagctta
     1381 ttgagtgtct tggctggtca aggtcagcta actgttgacg ggaaaaatta tccaattcaa
     1441 aaaggcagcc actttatcct accaagtgat gttgaagctt ggactctgga agggcaaggt
     1501 ttggaattga ttgttagcca tccataaaaa gaaagggcct gagttcacta ctcaagtcct
     1561 ttttgattac ataaattggg caatgaagac cacaatgatg atgattggaa tgacgaaacg
     1621 aagaaacgaa gaaggaagag ccagacttgg aacagtcctt gtttccatgc tctttcatcg
     1681 agatggagtt cctccattgc aagagccttt ttaaagatat agcctgtaaa aagtgaaagg
     1741 tagagagctc caaatggcat gaggagattg gaaaccaaga agtccatagc gtcaaagaag
     1801 gtcttaccaa aaatgtgaac atccgccatg acaccgtaag atagggctga aggaatgcca
     1861 aagacaaagg tcaaaattcc taaaataaca ctccatttgg cacgtttgct gttatcctgg
     1921 ttggtgatat tgtctacatt gatttccagc atcacgacag aaaaagtgac tgtcgcaaaa
     1981 aggaagagca agaggaagag gacgtagaaa atggttccaa aaggcatctt gtcaaagagt
     2041 tgaggcaaga cgataaagag caggctgggt cccccttcag actggatatt gaagggggat
     2101 cgagcttgga aaatggctag acctgccatg atggatatcg agatattcat ggctacgatg
     2161 gagattcctg actggactag attggttttc ttgtctaagt aagaagcata ggtcaacatg
     2221 actgtaaccc ctagtgagag ggcaaagaaa gattgtccca gagcatagag gagaccagtg
     2281 ctagtcagtt ttgaaaagtc tggtttgagg aagtaaagaa ccccttccat ggcatttggc
     2341 aaactgagag agcgaccgat gataaaaaca aagacgataa agagcagggg catcatgact
     2401 ttcgaagctc tttcaatccc tttttgaacc ccacgtgata caatgaagat attcaatagg
     2461 ataaaggccg cttgagctcc tagggcaatg gctggatttg aaatgattga agtaaataac
     2521 tgagcataat cacccgttcc accaagttgg aacaatttcc caaactcaat acctagatag
     2581 actagaatcc atcctccgat aacactgtaa aaagataaga ggataaagag ggcaaaggcg
     2641 ccaatccaac cgataaagtt gtacttgtta ttcttgccca gttttccaaa ggttttgata
     2701 gcggaaacgc cagcactacg gccaagggca aactcagcca gcaggagagg gaaaccgatt
     2761 aaaatagtgg aaatgagaaa gattagtaaa aagcctccac cgccattagc agcagtcatg
     2821 tagggaaact tccaaacgga accaagcccg atggccagcc agcagatgct agaataaaac
     2881 caagtttcga cccccattgt gatttttctg acatagttaa actctgatct cctttttcaa
     2941 aataagaaaa agctacttga gttgtcaaat agccttctgt ttgattgata gacttgacta
     3001 tcctatcatg ttttctaagg tctgtcaaga aaatcatttt caagttttca cacctttctc
     3061 aaaaaagtta aaaaattttc tcaaaaacgc ttgactctga cctaaggcga ggggttatac
     3121 tatcattgta aggaggaaat catgtaccat ataaaagaag ctgcgcagct ttcaggtgtc
     3181 tctgtcaaga ccctgcatca ctatgacaag ataggactct tggtcccctt aaagtcggaa
     3241 aacggctatc gaacctacag tcaagaggat ttggaacgcc ttcaggtcat tctttactac
     3301 aaatatctag gcttttcttt agagaaaata gcagagctgt taaaggaaga aaggacagat
     3361 ttattgcccc atttgactag gcagttggac tatctaactc gcgaaaggca acatctggat
     3421 accttgattt ccaccttgca aaaaactatt caagaacaaa aaggagaaag aaaaatgacc
     3481 attgaggaaa aattcacggg atttagctat caagacaatc aaaaatacca ccaagaagcg
     3541 gtagagaaat atggtcaaga agtcatggga caagcgctcg aacgccaaaa aggtcacgaa
     3601 gacgaggcta cggccgcctt taaccaagtc tttcaaactt tggcacaaaa tcttcaagtt
     3661 ggtttacctg caacagcaac cgaaaaccag gagcaagcag ccaagctctt gcaagccatt
     3721 cgcacttatg gatttgactg ctctattgag gtattcggtc atatcggtaa aggttacgtc
     3781 tacaacccag agtttaagga aaacattgac aagtttggtt ctgaaacagc ccagtacacg
     3841 tcagatgcca ttgcggttta cgttcagaca aatgcagaat aaataggcta ggaatttcct
     3901 agcctatttt ttacttcaaa tcataaagcc agtcgtcacc gtttttgtag taaaagaatt
     3961 cactgagatc ttcttctaga aacacacgaa gcatatcaga catatcatcg gttgcaagtt
     4021 ttagatgaga aagattttca aagtcctccc accaaacttt cccttcgtct gaagactgga
     4081 gttcaccagt aaagtgttct gtcttgtaaa aaaggacgac ataacgataa tccttgtcgt
     4141 cataccagtt tttgatacca cagagttggg gtttggaaat gatcagacca gtttcttctt
     4201 tcacttcacg aatgacagca tcgacaaagg attcgccacg ttcaacatga ccaccaggaa
     4261 aagtaatgcc agaccagtcg ggattaactc ggtcttggac caggacctta tctccgtttt
     4321 taatcataca catgttaaca aattcgactg cctctcttct gttcattctt cacaaccttt
     4381 aatctttaat cataatgcag acttcccgcc acccagccgg tacagagggc agaagtgatg
     4441 ttaaagccac ccgtgtgggc attgatatcc ataacttcgc ctgcaaagtg gaggccaggt
     4501 accagcttac tttcaagggt tttaggattg atttccttga gactgactcc acccttggta
     4561 acaaaggact ttgcaaggga catttttcca gttacaggaa ttttaagttc tttaatggac
     4621 tggacaagtt gttctcgttc cttttcagtc agttgtttga ctttttcagg atatccttgt
     4681 acaaaaaatt cggccaagcg ttctggtaac aaggttttta aagcgttttt caaggatttt
     4741 tcccgatttt cttctagaaa tgtaaccaag tccttctcag aaagttgagg caaaacatcg
     4801 agtgagagaa cctccccacc tttgacaaag ctagacatgc gtagggcagc aggacctgac
     4861 aaaccaaagt gggtaaagag taaatcatga gtgatgacat gcttaccata acttagggtc
     4921 acatcgtcca gagaaatacc ttgtaaggct ttatgtggaa aatctgttaa taaaggactt
     4981 tcagcagcct caagatcggt gatggtatgc ttaaaatggc gagcaatctc gtgaccaaaa
     5041 ccagtcgaac cagtcgaagg ataagactta ccacctgttg tgacaatgag tttctcacaa
     5101 gtgaaggttt gatccgctga cttaaggaca aactggtcat ctactttttt aacagaaacg
     5161 atttctattt gagtagcaac ttgaccacct agttcggtga ttttcttttc caaagcttcg
     5221 ataatagtcc gagacttgtc actggctgga aagacgcgtc cgtggtcttc gaccttaagt
     5281 ttaacaccat tttctgtaaa aaagttgatg atgtcatgat tatcgaactg ggagaaaaca
     5341 ctgtaaagaa agcgtccgtt tccaggaatt ccagctagca ggttgtctaa gctaccattg
     5401 ttggtcacat tgcaacgtcc cccaccagtc ccagctaatt tttttccaag tttccgattt
     5461 ttttcgatga ggagggtttt ctgtccataa aagctactgg aaatcgtagc catcatacca
     5521 gcaggtcccc caccgatgac aatagtatca aaatgtttca tagctctatt gtaccacaaa
     5581 aaaacaagag atgatggtca cctcttgtca agaatgcaat taatcaattt catagcccat
     5641 cagcaaaccg ccctcttctg catagaaact gcagagacca gaggttggta gaattttaat
     5701 atccgcttgt gggaaggttt cacggattcg ctctgagagc tgttgacaac atttttcgtt
     5761 attgcgttgg gccatgacaa tacggccacc agcatatcca gcttttacta actcatcata
     5821 ggcagcttga actgatttct ttgatcccct tgctttttgt agcaattcga gagtcccagt
     5881 ttcactagct tttccgacca tacgaatgtt gagaaggcca acgaccgtac cgataagctt
     5941 gctcaaacgg ccgttcttca ccaagttatc gactttggct aggacaaaga gcaacttagt
     6001 tttttcttga taggcggtga tagcttcaac cacttcttca aaagacaagc cctggtcaat
     6061 caagtcattc aatttttcta cgagtaggtc aacttcacca ccagcagata aactatcaat
     6121 cacatgaatc ttagtgtcag gatggtcttc cagataaata ttctttgcta gttgagcact
     6181 attgtgactg ccagaaaggg tacctgtgat ggttactagg aaaatgtttt tggcaccttc
     6241 aaatgctcgc aaatagtcat ctgggcttgg acaagccgat tttgaagctt ctgcagttgc
     6301 atacatggtt tccatcattt ggtcaatatc gagactggcg tcatcaacaa agacctgatc
     6361 agctacttga atggttaagg ggacacttac aaaggttgtg ttaatagctg gtgttggcag
     6421 ttgacgataa tcacaaccag agtcagcaat aatcttccaa gtcatagaaa ttctccatct
     6481 ttgtcagtta tacattgaca aaggttctgt ctttttttac aattatatca tgaaaaccct
     6541 tgaaacaaaa gcatcatccg tctgttgtga caagtagaaa gaaaatgtta tgtctgaacg
     6601 tagaatctct gaaaagtctc ttgaaaatct cagaaaatca aaccaagaat ccaatttatt
     6661 aaccagagaa gccattgaaa cagccctctt gcaactcttg gaaaaaaagg aactgaccaa
     6721 gattagtatt tctgaattgg tcaaacgtgc aggtgtttcg cgtgcggcct tttatcgcaa
     6781 ttatgactcc aaagaggaaa ttttagagag cgtctttaaa cgaactgtcc acaatattat
     6841 ggaacagctg catcattacg atttaaagac agacctttat ttggtttggg ttcacctttt
     6901 ccgggaggcc agaaaggaag ctagagtaat tcaattggcc ttggattacc atctggaaaa
     6961 aatctttgtc caagccatgc aggaatttct agaaaaatac catgggaaat caaaaggtgt
     7021 cagctcttat cttcattcct tctggagctc agccatcgtc tctgtccttc taaaatggat
     7081 caaggatggc atgaaggtac cagctgaaaa gattgcagat ttaggtttac cattttttaa
     7141 aaaatagaga aaaaggagaa aagagatgac tgaaaaaaga ctggcctggg atgagtattt
     7201 tgcagcccaa gctctactaa ttgcgaatcg ttccacttgt aaacgtgcta aagtgggcgc
     7261 gattctggta aaagataata aggttatttc cactggttac aatggttcgg tgtcagggac
     7321 tgagcattgt attgatcacg aatgtttggt cattgaaggc cactgcgttc gcacccttca
     7381 cgctgaggtc aatgctatcc ttcaaggtgc tgagcgtggt gttcccaaag gctttacagc
     7441 ctatgtaacc cattttcctt gtctcaactg tacaaaacaa ttgcttcagg tcggctgcaa
     7501 gcgcgtggtt tatatcaacc agtaccgaat ggacgactac gcccaatacc tttatcaaga
     7561 aaaagggaca gaattgaccc atttaccact tgagacagta cagacagctc ttaaagaggc
     7621 tgatctaatg taaaaattat caaaaataaa tggtttagaa agatttttaa accgtttttt
     7681 ggtataataa gaagaataaa ttgaaagaag gaattccaaa aatgggaaaa attgaagtta
     7741 ttaatcaccc actgattcaa cacaaattgt caatcttgcg tcgtacagat acttctacaa
     7801 aagcttttcg tgagctagta gatgagattg caatgttgat ggggtatgaa gtacttcgtg
     7861 atcttccact agaagatgtg gaaatcgaaa caccaattac aaaaacagtt caaaaacaat
     7921 tggcaggtaa gaaattggcc atcgtcccaa tcttgcgtgc aggtatcggg atggttgatg
     7981 gtctcttgaa cttggttcca gctgctaaag ttggccacat cggtatgtac cgtgatgaag
     8041 aaacacttca accagttgaa tacttggtga aattgcctga ggacattgac caacgtcaaa
     8101 tttttgtagt agacccaatg ttggcaacag gtggctcagc aatcttggct gttgattctc
     8161 ttaaaaaacg tggcgcatca aatatcaaat ttgtctgcct tgtatctgct ccagagggtg
     8221 taaaagccct tcaagaagct catccagatg tagaaatctt tacagcagcc ttggatgaac
     8281 gtttgaacga acacggttat atcgttccag gtcttggaga tgctggagac cgcttgttcg
     8341 gtacaaaata agatcgaaaa gaagaatgac ttggaaaagt atttccagtc acgaaaggag
     8401 gttgggtttt tgtttctgtc taatgaaagc agagcaaaaa tttgaccttt tttgaccaag
     8461 atattataat agtcttatct tcagtcattt gaccaacaaa attaaaactc aaaaggagaa
     8521 atgaatgatt cctgtagtta ttgaacaaac aagccgtgga gaacgttctt acgatattta
     8581 ctcacgtctt ctcaaagacc gcatcattat gctgacaggt ccggttgaag acaatatggc
     8641 taactctgtt attgcccaat tgcttttctt ggatgcccaa gatagtacaa aagatattta
     8701 cctttatgtc aatacaccag gtggttctgt ttcagctggt ttggcaatcg tagataccat
     8761 gaactttatc aaggcagatg tccaaaccat tgttatggga atggctgcat ctatggggac
     8821 tgtcatcgca tcaagtggag caaaaggcaa acgtttcatg cttccaaatg ctgaatacat
     8881 gattcaccaa ccaatgggtg gtacaggtgg tggtacccaa caaactgata tggctatcgc
     8941 tgcagaacac ttgctcaaaa ctcgtaatac cttggaaaaa atcttggctg aaaattcagg
     9001 tcagtcaatg gaaaaagtcc atgcagatgc agaacgtgat aactggatga gcgcccagga
     9061 aacacttgaa tatggcttta ttgatgaaat tatggccaac aattcattga actaatgatg
     9121 atagaaggca aactcgactg ggtttgcttt ttttggtata atagggagag atttcttaga
     9181 aagaggattt atcatgtttg aaaaagtcaa tcgctctggc ttgattatct atctttacta
     9241 taatcgtgat gccaaaaaac tgcaggatta tggagatatt acctatcatt ccaagaaaca
     9301 tcgttactta caactctatg ttccaactca agaagtggag caattggtcg gacgcttgag
     9361 caaggaaaaa tttattaaaa aagttagggt ttgtcatatc caagagttgg aaacaccctt
     9421 tgtgggcaat ctttatcgat aggaaaacgt tatcatcgaa aaagttcaag gaaaacattg
     9481 acaattttct gataattcgg tatattctta acagactatt taagaaataa ggagacaaaa
     9541 agatgaagaa aaaatttgcc ctatcgtttg tggcgcttgc aagtgtagca cttcttgcag
     9601 cctgtggaga agtgaagtct ggagcagtca acactgctgg taactcagta gaggaaaaga
     9661 caattaaaat cgggtttaac tttgaagaat caggttcttt agctgcatac ggaacagctg
     9721 aacaaaaagg tgcccaattg gctgttgatg aaatcaatgc cgcaggtggt atcgatggaa
     9781 aacaaatcga agtagtcgat aaagataata agtctgaaac agctgaggct gcttcagtta
     9841 caactaacct tgtaacccaa tctaaagtat cagcagtcgt aggacctgcg acatctggtg
     9901 cgactgcagc tgcggtagcg aacgctacaa aagcaggtgt tccattgatc tcaccaagtg
     9961 cgactcaaga tggattgact aaaggtcaag attacctctt tattggaact ttccaagata
    10021 gcttccaagg aaaaattatc tcaaactatg tttctgaaaa attaaatgct aagaaagttg
    10081 ttctttacac tgacaatgcc agtgactatg ctaaagggat tgcaaaatct ttccgcgagt
    10141 catacaaggg tgaaatcgtt gcagatgaaa ctttcgtagc aggtgacaca gacttccaag
    10201 cagcccttac aaaaatgaaa gggaaagact ttgatgctat cgttgttcct ggttactata
    10261 atgaggctgg taaaattgta aaccaagcgc gtggcatggg aattgacaaa ccaatcgttg
    10321 gtggtgatgg attcaacggt gaggagtttg tacaacaagc aactgctgaa aaagcatcaa
    10381 acatctactt tatctcaggc ttctcaacta ctgtagaagt ttcagctaaa gctaaagcct
    10441 tccttgacgc ttaccgtgct aagtacaatg aagagccttc aacatttgca gccttggctt
    10501 atgattcagt tcaccttgta gcaaacgcag caaaaggtgc taaaaattca ggtgaaatca
    10561 agaataacct tgctaaaaca aaagattttg aaggtgtaac tggtcaaaca agcttcgatg
    10621 cagaccacaa cacagtcaaa actgcttaca tgatgaccat gaacaatggt aaagttgaag
    10681 cagcagaagt tgtaaaacca taatagaaaa atgttgaaat agggaatgag cctttgactc
    10741 actccctgtt tcgatattta atactcttcg aaaatctctt caaactgcgt caacgtcgcc
    10801 ttggattata tatgtgactg acttcgtcag tcttatctac aacctcaaag cagtgctttg
    10861 agcaacctgc ggctagtttc ctagtttgct ctttgatttt cattgagtat aagaacctat
    10921 caaaaagtga gggaaaaccc tcggaattat aaatagaaag agtgaatctt atgctccaac
    10981 aactcgtaaa tggtttgatt ctaggtagtg tttacgcgct gttagcccta ggatatacca
    11041 tggtttacgg aattatcaag ctcatcaact tcgcccatgg tgatatttat atgatgggag
    11101 cctttatcgg ttatttcttg atcaattctt tccaaatgaa tttctttgta gcgcttattg
    11161 tagctatgct agcgacagct attcttggtg tcgtgattga gtttcttgct taccgacctt
    11221 tgcgccactc tactcgtatt gctgttttga ttacggctat tggggtttct ttcctattgg
    11281 agtatggaat ggtctatctg gttggtgcca atacccgtgc cttccctcaa gcgattcaaa
    11341 cagttcgata tgatttggga ccaattagct taacaaatgt gcagttaatg attttggcca
    11401 tttccttgat tttgatgatt ttgttacaag tcattgtcca aaagactaag atggggaaag
    11461 ccatgcgtgc agtatcagta gatagcgacg cggcgcaatt gatggggatc aatgtaaacc
    11521 gtacgattag ctttaccttc gctttgggtt ctgctcttgc gggtgcggct ggtgttctga
    11581 ttgctcttta ttataactct cttgagcctt tgatgggggt tactccaggt cttaaatctt
    11641 tcgttgccgc agtacttggt ggtatcggaa ttattcctgg tgcggctctt ggtggctttg
    11701 tgattggtct attggaaacc tttgcgactg cctttgggat gtcagatttc cgtgatgcca
    11761 ttgtttatgg aatcttgttg ttgatcttga ttgtccgccc agctggtatc cttggtaaga
    11821 atgtgaaaga gaaggtgtaa acgatgaagg aaaatttaaa agttaatatt ctatggttac
    11881 tccttttgtt agctggctat agcttgatta gtgtactggt ttcagtcgga gtacttaatc
    11941 tattctatgt acagatttta caacaaattg gaattaatat tattttggct gttggtctca
    12001 acttaatcgt tggtttttca ggacaatttt cacttggtca tgctggtttc atggcgattg
    12061 gtgcctatgc agcagctatt attggttcta aatcaccaac ctacggtgcc ttctttggag
    12121 ctatgcttgt aggggctttg ctttcaggag cagttgcctt acttgtcggc attccaacct
    12181 tgcgcttgaa gggggactat cttgcggtag caactctggg tgtttctgaa attatccgta
    12241 tctttatcat caatggtgga agccttacaa atggtgcggc aggtatctta gggattccta
    12301 actttacaac ttggcaaatg gtttacttct ttgtcgtgat tacaaccatt gcaaccttga
    12361 acttcttgcg tagcccaatt ggtcgttcaa ccctctctgt tcgtgaagat gaaatcgctg
    12421 ctgagtcagt tggggttaat acgactaaaa ttaaaatcat cgcttttgtc tttggtgcca
    12481 ttactgcaag tattgctggg tcacttcagg caggatttat cgggtctgtt gtaccgaaag
    12541 attacacctt catcaactca atcaacgttt tgattattgt tgtatttggt ggactcggtt
    12601 ccattacagg tgcgattgtt tcggctattg ttctgggaat tttgaatatg cttctccaag
    12661 atgttgctag tgtgcgtatg attatttacg ctttggcctt ggtattggta atgattttca
    12721 gaccaggtgg actccttgga acatgggaac tgagcctatc acgtttcttt aaaaaatcta
    12781 agaaggagga acaaaactaa tggcattact tgaagtaaaa cagttaacca aacattttgg
    12841 tggtctaaca gctgttggag atgtgactct tgaattgaac gaaggggaac tggttggatt
    12901 aatcggtcca aacggagctg ggaaaaccac ccttttcaac cttttgaccg gtgtttatga
    12961 accaagcgag ggaacagtaa ccctagatgg tcaccttttg aatgggaaat caccttataa
    13021 gattgcctct ttgggacttg gacgtacttt ccaaaatatc cgtctcttta aagatttaac
    13081 agttttagat aatgttttga ttgcttttgg aaaccatcac aaacagcatg tttttactag
    13141 tttcttacgc ttaccagctt tttacaagag tgaaaaagaa ttaaaggcta aagctttgga
    13201 attgttgaaa atctttgatt tagatggtga tgcagagact cttgctaaaa atctttccta
    13261 cggacaacaa cgtcgtttgg aaattgttcg tgcccttgct acggaaccta aaattctctt
    13321 cttagatgaa ccagcagcag gtatgaaccc acaggaaaca gccgaattga ctgagttaat
    13381 tcgtcgtatc aaagatgagt ttaagattac aatcatgttg attgaacacg atatgaatct
    13441 ggtcatggaa gtaacagaac gtatctacgt acttgaatat ggccgtttaa tcgctcaagg
    13501 aactccagac gaaattaaga ccaataaacg cgttatcgaa gcttatctag gaggtgaagc
    13561 ctaatgtcta tgttaaaagt tgaaaatctt tctgtgcatt acggtatgat ccaagcagtt
    13621 cgtgatgtaa gctttgaagt taatgaagga gaagttgttt cccttatcgg tgccaacggt
    13681 gcaggtaaga caactattct tcgcaccttg tcaggtttgg ttcgaccaag ttcaggaaag
    13741 attgaatttt taggtcaaga aatccaaaaa atgccagctc agaaaatcgt ggcaagtggt
    13801 ctttcacaag ttccagaagg acgccacgtc tttcctggct tgactgttat ggaaaatctt
    13861 gaaatgggag ctttcttaaa gaaaaatcgt gaagaaaatc aagctaactt gaagaaggtt
    13921 ttctcacgct ttcctcgtct tgaagaacgg aagaaccaag atgcagccac tctttcaggg
    13981 ggggaacaac aaatgcttgc catgggacgc gccctcatgt caacaccaaa acttcttctt
    14041 ttagatgaac catcaatggg acttgcccca atctttatcc aagaaatttt tgatatcatt
    14101 caagatattc agaagcaagg aacaacggtc ctcttgattg aacaaaatgc caataaagca
    14161 cttgcaatct ctgaccgagg atatgtactg gaaacaggga gaatcgtcct atcaggaaca
    14221 ggaaaagaac tcgcttcatc agaagaagtc agaaaagcat atctaggtgg ctaaaacaat
    14281 ccagtggatt gttttagtcg gcagatggag attacgaagt aatcatcaat atagtccggg
    14341 ggaccttttt agtcggtaga ttgagattgc aaacaaatct gcatctacat tgaaagctta
    14401 atttctaata attgaaaaaa tcgaatgaaa aatttcttac cttcattcac agagctcgat
    14461 ttcagagctc tttttgctag cttattcata cttttctgaa tttcgaaaaa gaaatgtaag
    14521 cgtttgatag atttacaaaa agattgtata atagggataa gaatagaaaa ggagaagtct
    14581 catggcagtt aaagatttta tgacccgcaa ggtagtttat attagtccag atacaacagt
    14641 atctcatgca gcagatttga tgagagagca aggtttgcac cgtctgcctg ttatcgaaaa
    14701 tgatcaatta gttggtttgg tgactgaggg aaccattgca caagcaagtc catctaaagc
    14761 aacaagtctt tctatctatg agatgaatta tcttctgaat aagacaaaag taaaagatgt
    14821 catgattcgc gatgttgtca ctgtctcagg ctatgctagt ctagaagatg caacttatct
    14881 gatgttgaaa aataagatta gtattctccc tgtcgtagat aaccatcaag tatacggagt
    14941 tattactgac cgtgacgttt tccaagcctt tcttgaaatt gcaggttatg gcgaagaagg
    15001 gattcgtgta cgctttgtta cagaagatga agttggtgtt cttggaaaaa ttgtttcttt
    15061 gattgtagaa gaaaatttga atatctccca tacagtcaat attccgcgta aggatggtaa
    15121 ggtgattatc gaagtgcaaa tcgatggatc aattgattta ccagccttga aagaaaaatt
    15181 tgaagcaaat ggtattcaag tggaagaaat cgctcgcact tcagcaaaag tcttgtaaga
    15241 agggaagccc aaaggcttct tttttcatga aaaggggatt agagcaaaag atggaaagaa
    15301 atgataaaat atgctataat gaaataatgt aaaaaaggag tatttatgga catttcagta
    15361 attcgtcaga aaattgacgc aaatcgtgaa aaattagctt ctttcagggg gtctctttga
    15421 cctcgaaggg ctagaggaag agattgccat cttggaaaac aagatgacag aacctgattt
    15481 ttggaacgat aatattgcgg cccaaaaaac gtcgcaagaa ttaaatgaat taaaaaacac
    15541 ttacaatacc ttccataaga tggaagagtt gcaggatgaa gtcgaaattt tattggattt
    15601 tttggctgaa gacgagtcag tgcatgatga actggtagcg cagttagccg aacttgataa
    15661 gataatgacc agctacgaga tgactctact cttgtcagaa ccttatgacc acaacaatgc
    15721 catcttggaa atccatccag gttctggtgg tactgaggcg caggactggg gtgatatgtt
    15781 gcttcgtatg tatactcgtt atggtaatgc taaaggcttt aaagtggaag tgttggatta
    15841 ccaagcaggt gatgaggctg gtattaagtc ggtaacttta tcatttgaag ggcctaatgc
    15901 ctatggtctc ctcaagtcag aaatgggtgt tcaccgctta gtgcgaatct caccatttga
    15961 ctctgccaaa cgtcgccata cctctttcac atctgtagaa gtgatgccag aattggatga
    16021 tactattgaa gtggaaatcc gtgaagatga tatcaagatg gataccttcc gttcaggtgg
    16081 tgccggtgga caaaacgtca ataaggtttc aacaggtgta cgtttaaccc acattccaac
    16141 tggaattgtt gtccaatcaa cagtagatcg tacccagtat ggaaatagag atcgtgccat
    16201 gaagatgttg caggctaagc tctatcaaat ggagcaagat aagaaggctg cggaggtaga
    16261 ttctctcaaa ggtgagaaaa aggagatcac ttggggaagc caaatccgtt cttatgtctt
    16321 cacgccttat actatggtaa aagatcaccg aactagcttt gaggttgctc aggtagataa
    16381 ggttatggat ggggacctag atggttttat cgatgcttat ctcaagtggc gaattagcta
    16441 agatagaaag gaactcacat gtcaattatt gaaatgagag atgtcgttaa aaaatacgac
    16501 aacggaacaa ctgctctacg cggtgtttcg gttagcgttc aaccggggga atttgcttac
    16561 atcgtaggac cttcaggagc agggaagtca acttttattc gttctctgta tcgtgaagta
    16621 aaaatcgata aaggaagcct atcagttgct ggttttaatc tggttaagat caaaaagaaa
    16681 gatgtcccgc ttctacgtcg tagtgttggg gttgtcttcc aggattataa attgttacca
    16741 aagaaaactg tctatgaaaa tattgcttac gctatggaag taatcgggga aaatcgccgt
    16801 aatatcaaaa gacgagtgat ggaagttttg gacttggttg gattgaagca taaggttcgt
    16861 tctttcccaa atgaactctc aggtggggag caacagcgga ttgcgattgc gcgtgcaatt
    16921 gtaaataatc ccaaagtatt gatagctgat gagccaacag gaaatctgga tccggataat
    16981 tcatgggaaa ttatgaatct cttggaacgg attaacctac aaggaacaac tattttgatg
    17041 gcgactcata atagccagat tgtaaatacc ttgcgccacc gtgtcattgc cattgaaaat
    17101 ggccgtgtcg ttcgtgacga atcaaaagga gagtatggat acgatgatta gtagattttt
    17161 tcgccattta tttgaagcct taaaaagttt gaaacgaaat ggttggatga cagtagctgc
    17221 tgtcagttca gtcatgatta ctttgacctt ggtggcaata tttgcatctg ttattttcaa
    17281 tacagcgaaa ctagctacag atattgaaaa taatgtccgt gtagtagttt atatccgaaa
    17341 ggatgtggaa gataatagtc agacaattga aaaagaaggt caaactgtta caaataatga
    17401 ctaccacaag gtatatgatt ctttgaagaa catgtctacg gttaaaagtg ttaccttttc
    17461 aagtaaagaa gaacaatatg aaaaattaac cgagataatg ggagataact ggaaaatctt
    17521 tgaaggagat gccaatcctc tctatgatgc ctatattgta gaggcaaaca ctccaaatga
    17581 tgtaaaaact atagccgaag atgctaaaaa aattgaaggt gtctctgagg ttcaagatgg
    17641 cggtgccaat acagaaagac tcttcaagtt agcttcattt atccgtgttt ggggactagg
    17701 gattgctgct ttgttaattt ttatcgcagt tttcttgatt tcaaatacca ttcgtattac
    17761 cattatttcc cgcagtcgcg aaattcaaat catgcgcttg gtcggagcta aaaacagtta
    17821 tatccgtgga ccgttcttgt tagaaggagc ctttatcggt ttattgggag ctatcgcacc
    17881 atctgttttg gtctttattg tttatcaaat tgtttaccaa tctgtcaaca aatcgttggt
    17941 agggcaaaat ctatccatga ttagtccaga tttatttagt ccgttgatga ttgccctact
    18001 atttgtgatt ggggttttca ttggttcatt gggatcagga atatccatgc gccgattctt
    18061 gaagatttag gtaaaatagc tgcttttatg aggagattgt aaaatctcct tttttgctac
    18121 aagagttttt gaaaagagat gcgcagaaga aaagagcttc caaagaagtc ccccagagaa
    18181 gacttcttga tggctaattt gaacttgaaa tttggcgcac tagaaatttt ttagaaaaaa
    18241 gtgtaatttt tttataaaag cctttacaaa aaaaattaaa gtggtataat taaatcatag
    18301 aaagtgcaaa cgttttcgta aaacgtttac ctaaataaaa ataaaggaga tttgaatgat
    18361 gaaagataca ttcaaaaatg tcttgtcttt cgaattttgg caaaaattcg gtaaggcttt
    18421 gatggtagtt atcgcggtta tgccggctgc tggtttgatg atttcaatcg gtaagtctat
    18481 cgtgatgatt aacccaacct ttgcaccact tgtcatcaca ggtggaattc ttgagcaaat
    18541 cggttggggg gttatcggta accttcacat tttgtttgcc ctagccattg gaggaagctg
    18601 ggctaaagaa cgtgctggtg gtgctttcgc cgctggtctt gccttcatct tgattaaccg
    18661 tatcactggt acaatctttg gtgtatcagg cgatatgttg aaaaatccag atgctatggt
    18721 aactactttc tttggtggtt caatcaaagt tgctgattac tttatcagtg ttcttgaagc
    18781 tccagccttg aacatggggg tattcgtagg gattatctca ggttttgtag gggcaactgc
    18841 ttacaacaaa tactacaact tccgtaaact tcctgatgca ctttcattct tcaacgggaa
    18901 acgtttcgta ccatttgtag ttattcttcg ttcagcaatc gctgcaattc tacttgctgc
    18961 tttctggcca gtagttcaaa caggtatcaa taacttcggt atctggattg ccaactcaca
    19021 agaaactgct ccaattcttg caccattctt gtatggtact ttggaacgtt tgctcttgcc
    19081 atttggtctt caccacatgt tgactatccc aatgaactac acagctcttg gtggtactta
    19141 tgacatttta actggtgcag ctaaaggtac tcaagtattc ggtcaagacc cactatggct
    19201 tgcatgggta acagaccttg taaaccttaa aggtactgat gctagtcaat atcaacactt
    19261 gttagataca gtacatccag ctcgtttcaa agttggacaa atgatcggtt cattcggtat
    19321 cttgatgggt gtgattgttg ctatctaccg taatgttgat gctgacaaga aacataaata
    19381 caaaggtatg atgattgcaa cagctcttgc aacattcttg acaggggtta ctgaaccaat
    19441 cgaatacatg ttcatgttca tcgcaacacc tatgtatctt gtttactcac ttgttcaagg
    19501 tgctgccttc gctatggctg acgtcgtaaa cctacgtatg cactcattcg gttcaatcga
    19561 gttcttgact cgtacaccta ttgcaatcag tgctggtatt ggtatggata tcgttaactt
    19621 cgtttgggta actgttctct ttgctgtaat catgtacttt atcgcaaact tcatgattca
    19681 aaaattcaac tacgcaactc cagggcgcaa cggaaactac gaaactgctg aaggttcaga
    19741 agaaaccagc agcgaagtga aagttgcagc aggctctcaa gctgtaaaca ttatcaacct
    19801 tcttggtgga cgtgtaaaca tcgttgatgt tgatgcatgt atgactcgtc ttcgtgtaac
    19861 tgttaaagat gcagataaag taggaaatgc agagcaatgg aaagcagaag gagctatggg
    19921 tcttgtcatg aaaggacaag gggttcaagc tatctacggt ccaaaagctg acattttgaa
    19981 atctgatatc caagatatcc ttgattcagg tgaaatcatt cctgaaactc ttccaagcca
    20041 aatgactgaa gcacaacaaa acactgttca cttcaaagat cttactgagg aagtttactc
    20101 agtagcagac ggtcaagttg ttgctttgga acaagtaaag gatccagtat ttgctcaaaa
    20161 aatgatgggt gatggatttg cagtagaacc tgcaaatgga aacattgtat ctccagtttc
    20221 aggtactgtg tcaagcatct tcccaacaaa acatgctttt ggtattgtga cggaagcagg
    20281 tcttgaagta ttggttcaca ttggtttgga cacagtaagt cttgaaggta aaccatttac
    20341 agttcatgtt gctgaaggac aaaaagttgc agcaggagat ctccttgtca cagctgactt
    20401 ggatgctatc cgtgcagcag gacgtgaaac ttcaacagta gttgtcttca caaatggtga
    20461 tgcaattaaa tcagttaagt tagaaaaaac aggttctctt gcagctaaaa cagcagttgc
    20521 taaagtagaa ttgtaatata cttgaggttg gaagctgtat tccaacctct tattttggga
    20581 gaaaagaatg aaatttttaa cactcaatac tcacagttgg atggagaaag aagcagagga
    20641 aaaattccag attttgcttg aagatattct tgaaaaggac tatgatttga tttgttttca
    20701 agaaatcaat caggagatga cctcgtcaga ggtggaggtt aatgaccttt atcaagcttt
    20761 gccagcagct gagcctattc accaagacca ttatgttaga ctcttggttg aaaagttgtc
    20821 tgagcaaggg aaaaattact actggacctg ggcctataac catatcggct ataaccgcta
    20881 ccacgaaggt gtggctatct tgtctaaaac acctattgaa gccagagaaa ttttggtttc
    20941 agatgtggat gatccaacag actatcatac tcgccgtgtt gccctagctg aaactgtagt
    21001 cgatggcaag gagctagcag ttgccagtgt tcatctctct tggtgggata aaggtttcca
    21061 agaagaatgg gcacgatttg aggctgtctt gaaaaaattg aacaagccac ttttactagc
    21121 tggagatttc aacaatccgg ctggacagga aggttaccaa gctattttag ctagtccatt
    21181 aggcttacaa gacgcatttg aagttgctca agagaaaagt ggtagctata ctgttccgcc
    21241 tgaaattgat ggctggaaag ggaacactga accccttcga atcgattatg tctttactac
    21301 caaagagtta gcggtggaaa atttacatgt cgtatttgat ggtaacaaga gtccacaagt
    21361 gagtgatcac tatggcttga atgctatatt aaactggaaa taataactga aaagaggttg
    21421 gaactataaa attccagcct tttcttacta gagaagctac tggaaatagc ctaaataagt
    21481 gagactactg taatggaata aaatatggta taattgataa ggtagataga atcgaggatg
    21541 ttatgtcatt tacgaaattt caatttaaaa actatattag agaagccttg aaggagttaa
    21601 aatttacaac tccaacagag gtgcaagaca agttgattcc tattgttttg gcaggtcgtg
    21661 acctagtagg agaatcaaaa acaggttcag gtaagactca tactttcttg ttaccgattt
    21721 tccagcaatt agatgaagct agcgatagtg tacaagcagt gattactgca ccgagtcgtg
    21781 agttggctac tcaaatttac caagtagcgc gtcagatttc agctcactca gatgtcgaag
    21841 ttcgtgtggt taattatgtg ggtggtacgg ataaggctcg ccagattgag aaattggcaa
    21901 gcaatcagcc tcatattgtt attggaacac caggccgtat ctacgacttg gttaaatctg
    21961 gtgatttagc tattcataaa gccaagacat ttgttgttga tgaagcagat atgaccttgg
    22021 atatgggatt cttggaaact gttgataaga ttgctggcag tcttccaaaa gacttgcaat
    22081 tcatggtctt ctcagcgact atcccacaaa aactgcaacc attcttgaaa aaatacttat
    22141 caaatcctgt tatggagaaa attaagacca aaacggttat ttctgacacc attgataatt
    22201 ggttgatttc gaccaaggga catgataaga atgctcaaat ttaccagttg actcagttga
    22261 tgcagccgta tttggcaatg atttttgtta acactaaaac gcgtgctgat gaattgcatt
    22321 catatctgac tgctcaaggc ttgaaggttg caaaaatcca tggcgatatt gcccctcgtg
    22381 aacgcaagcg aatcatgaat caggtgcaaa atctggattt tgagtatatt gtcgcaacag
    22441 atttggcagc gcgtgggatt gacattgaag gtgtcagcca tgtcatcaat gatgccattc
    22501 cgcaagactt atcttttttt gttcatcgtg ttggtcgtac tggacgaaat ggcctaccag
    22561 gtacagctat taccctttat cagccaagtg atgactcgga tatccgtgag ttggagaaat
    22621 tgggaatcaa gtttagtcct aagatggtca aagacgggga atttcaagat acctatgacc
    22681 gtgatcgtcg tgccaaccgt gagaaaaaac aagataaact tgatatcgaa atgattggtt
    22741 tggttaaaaa gaaaaagaaa aaagtcaaac cgggttataa gaagaaaatt caatgggcgg
    22801 ttgatgaaaa gcgccgtaaa accaagcgtg ctgaaaatcg cgctcgcggt cgtgcagagc
    22861 gtaaagctaa acgccaaaca ttttaataga aattgttgga gtattgagct ccaacttttt
    22921 tatttatgag aacgaactat ctaaaccgaa acactacatt aaagactgca aattgcgatt
    22981 aaaaatggta taatgataaa gttatatagt cccgataaga tggtaggtat ttattacgaa
    23041 gagttttcct atcagtactt tgtaactcta taacaatatt ttttaagggg ggacattttt
    23101 atgtcagagc gtaaattatt cacgtctgaa tctgtatctg aggggcatcc ggataagatt
    23161 gcagaccaaa tttcagatgc gattttggat gctattttag caaaggatcc agaggcgcac
    23221 gttgctgctg aaacagctgt atatactggt tctgtccacg tttttggtga aatttctaca
    23281 aatgcctatg tggatattaa ccgtgtggtt cgtgatacca ttgcagagat tggttatacc
    23341 aatacagaat atggattttc tgctgagacg gtgggagtac acccatcttt ggtggaacaa
    23401 tctcctgaca tcgctcaagg tgttaacgaa gccttggagg ttcgtggaaa tgctgatcaa
    23461 gatccactgg acttgattgg agcaggtgac caagggctca tgtttggatt tgcagtagat
    23521 gaaacagaag agcttatgcc attgccaatt gcactcagtc ataaattggt tcgtcgtctg
    23581 gcagaacttc gtaagtctgg agaaattagc tatctccgtc cagatgcaaa atcacaagtt
    23641 acagttgagt acgatgaaaa tgaccgtccg gtacgtgtag atacagtcgt tatttctact
    23701 cagcatgatc cagaggccac taatgaacaa atccatcaag atgtgattga caaggtcatc
    23761 aaagaagtta ttccatcttc ttatcttgat gataagacaa aattctttat caatccgaca
    23821 ggtcgttttg taatcggtgg tcctcaaggg gactcaggtt tgactggtcg taagattatt
    23881 gtagatactt atggtggcta ctctcgtcat ggtggtggtg ccttctctgg taaagatgcg
    23941 actaaggtgg atcgttcagc ctcttatgcg gctcgctata ttgccaagaa tatcgttgca
    24001 gcagaccttg ctaagaaggc agaagtgcag ttggcctatg ctatcggtgt tgcgcaacct
    24061 gtttctgttc gtatcgatac tttcggtaca ggaacagtag ctgaaagtca acttgaaaaa
    24121 gcggctcgtc aaatctttga ccttcgccct gcagggatta tccaaatgct ggacctcaag
    24181 cgtccaattt accgtcaaac atcggcttac ggtcacatgg gacgtacaga tattgatctt
    24241 ccatgggaac gtttggataa ggtagatgct ttgaaagaag cagtaaaata agattttaag
    24301 aggggaacgt cctctctttt ttatagtttt taactatact gggatactgt tctgaaaatc
    24361 cattttgcga aagtagagat ttacatgtat agtagattga aactagaata gtacacctca
    24421 acttctaaaa cattgttagc aatcaatttg actgtcctga tcgatttctc ctgttcttgt
    24481 ttcattttac tatatttctt taaaaatgat aaaggttaag atttctcctc gtaatagata
    24541 atcttgggga tatttcaatc caaagtttta ttcgttatca cttgactatt gcaaggtttt
    24601 ctagagcaac agagtcatgg aatggactca tggttgagat ttctccttgt tgcttggact
    24661 tcattcaaaa gtctgttacc caagccttgt tcaaacttct aatacactag ctgtttccat
    24721 agcatgactt ctgtactaga ctttcttttc cgaataaata gatagaacca cagaatctag
    24781 taaacctaga attaaaatta tggtataata ttagcaataa aagaaatctg gaggattaga
    24841 atcatggtat caacgaaaac acaaattgct ggttttgagt ttgacaattg cttgatgaat
    24901 gcagcaggtg tggcttgtat gacgatagag gagttagaag aggtcaaaaa ctcagcggca
    24961 ggaacctttg ttactaagac agcgaccttg gacttccgtc aggggaatcc tgagccacgc
    25021 taccaagatg ttccacttgg ttccatcaac tctatgggct tgccaaataa tggcttagac
    25081 tattatttgg attatctttt agatttgcag gaaaaagagt cgaaccgaac tttcttctta
    25141 tctctggtcg gcatgtctcc agaggaaacc catactattt tgaaaaaagt ccaagagagt
    25201 gattttcgtg gtctgactga gctaaatctt tcctgtccaa atgttccagg taaacctcag
    25261 attgcctatg attttgagac aacagaccgg attttggcag aagtgtttgc ttacttcacc
    25321 aaacctcttg gaattaaatt gccaccttat tttgatattg ttcactttga ccaagcggca
    25381 gctattttca acaaatatcc gctcaagttt gtcaactgcg ttaactctat cggaaacggc
    25441 ctctatatag aagacgaatc tgtcgttatt cggcctaaga atggttttgg tggaattggt
    25501 ggagaataca tcaaaccgac tgctttagcc aatgttcacg ccttttatca acgtttaaat
    25561 cctcaaatcc aaattatcgg aacaggtggc gttctgactg gtcgagatgc ctttgaacac
    25621 atcctctgtg gagcaagtat ggtgcaggtg ggaacgaccc ttcacaaaga aggcgtcagt
    25681 gcttttgacc gcattaccaa tgaactgaaa gcaatcatgg tggaaaaagg ctacgagagc
    25741 ttagaagatt tccgtgggaa attgcgctat attgactaaa ttaaatcgaa aaatctgaag
    25801 aaaggagaga cgatgctagc cattgaagaa agtcagaagt tgactttatc aaatttaccg
    25861 agcctgagcc tatttacagg gacagatcag ggtcagtttg aagtgatgaa gagtcaaatg
    25921 ttgaaacaga ttgggtatga ttctgctgac ctcaactttg cctactttga tatgaaagaa
    25981 gtagtttaca aggatgtgga actggagttg gtcagccttc ctttctttgc ggatgagaaa
    26041 atcgtgatat tagattattt tatggatatc acgactgcta agaaacgctt tttgacagat
    26101 gatgagctta agtcatttga ggaatacctt gacaatcctt ctccaacaac caagttgata
    26161 atctttgcag aaggaaagct ggatagcaaa agacggttag tcaaattact taagcgtgat
    26221 gccaaggcct tcgatgcagt agaagtaaaa gaacaagaat tgcgccagta cttccaaaag
    26281 tggagtcaga aacaaggtct gcagtttacc aatcattctt ttgaaaatct cctcatcaag
    26341 tcggggtttc aatttagcga aatccagaaa aatcttctct ttttacagtc ctataaggcg
    26401 aattctgtta ttgaggaaga ggatattgtt aacgcaattc ccaagacctt gcaggacaat
    26461 atttttgatt taactcagtt tattctgact aaaaagatgg atcaggcgcg cgatttggtg
    26521 agagacttga ccttgcaagg ggaagatgaa atcaaactga ttgcagtcat gctgggacaa
    26581 tttcggactt ttactcaggt gaagattttg gcggagtctg gccaaacaga atcgcagatt
    26641 gcaagtagtt taggtagtta tctgggacgt aacccaaatc cttatcaaat caagtttgca
    26701 ttaagagatt cgagaggact ttctttgagc tttttgaagc aagctatttc ctatttgatt
    26761 gagacagact atcagattaa gacaggtctt tatgaaaaag gtttcctttt tgaaaaggca
    26821 ctcttacaga ttgctagtca ggtcaattga catttgttga aactacaacc cgcgtcagga
    26881 ctatcttgtc gtgggtttct tgctgatttg cttattttat tagaaagtat gtcagtgatt
    26941 tccttatcta taagcaaaaa acttgaaaaa agtgaatgtt tgcgttatca ttttcatata
    27001 gaaagaaaaa gaggtattac agatggctat tatcttacca gaacttccat atgcatacga
    27061 cgctttggaa ccatacatcg atgcggaaac aatgcatttg caccatgaca aacaccatca
    27121 aacttatgtc aacaatgcca atgcagcttt agaaaaacac cctgaaatcg gtgaagacct
    27181 tgaagccttg cttgctgatg tagaatctat cccagctgat atccgtcaag cacttatcaa
    27241 caatggtggc ggacacttga accacgctct tttctgggaa ttgatgactc ccgagaaaac
    27301 agctccttca gcagaactgg cagcagcaat cgatgcaaca tttggttcat ttgaagaatt
    27361 ccaagcagcc ttcactgcag cagcaacaac tcgttttggt tcaggttggg catggttggt
    27421 tgtcaacaaa gaagggaaac ttgaagtgac ttcaacagca aaccaagaca caccaatctc
    27481 agaaggtaaa aaaccaatct tgggcttgga cgtttgggaa catgcttact acgtgaaata
    27541 ccgcaacgtg cgtcctgact acatcaaagc tttcttttca gtaatcaact ggaataaagt
    27601 agatgaattg tacgcagctg ctaaataatg atagttggag ggaagaattg ttcttctctt
    27661 tttaggttat aagattctgg tctgacaaaa tcgtcagact tttttcattt ttatgagaaa
    27721 cgtgctaact gctagaaatt atggtagaat aaagtattaa gtaatcgtga aaaaaggata
    27781 tctatgcgaa aagaaattgc acctgaatta tacaactata acaagtttcc tggtccggag
    27841 ttccatttac acggggacaa ggtcgaaacg gaagggatag ctttttcctt ggttgaaaat
    27901 atcaaggatg cctttgatgt gacgactttt aatcagcgtt tttcagaagt attaaccaag
    27961 tttgattata tcgtggggga ctggagcaac gaacagcttc gcctacgagg tttttacaag
    28021 gatgaccgaa cagaagaaaa acttgaaaaa atcagtcgtt tacaagacta ccttttagag
    28081 tattgtagtt atggttgtgc ctattttgtc ttagaaaatg aagcccctaa gcgagcatca
    28141 tttgacaaga aaatgcgtaa gacggaagaa gaaacacctt ctagaaaagg aaagaaaccg
    28201 actcaaacta aacgaaagtc gaatgcagat aagaaaaata gacgtcgtca gaaagacgac
    28261 aagggacaac gtcattttgt cattcgtcag aagtgagtag agaataagga gaagaaatga
    28321 aaccctcaat tcatagtttg gtacatcaaa ccatgcagga atgggtattg gagcagggag
    28381 aaaagaaatt ccgtgcagat caaatctggg aatggctcta ccgtaaacgt gtgcagtcat
    28441 ttgaagaaat gaccaacctt tccaaggatt tgattgctaa gctcaatgac cagtttgtgg
    28501 tcaatccctt gaaacaacgt attgtgcaag agtctgctga tggtacagtc aaatatctct
    28561 ttgaattgcc cgacggtatg ttaattgaga ctgtactcat gcgtcaacac tatggtttat
    28621 ctgtctgtgt gaccactcag gtcggctgta atatcggttg taccttctgt gcctctggtt
    28681 tgattaagaa gcaacgtgac ctcaataacg gtgaaatcgt agcgcaaatc atgctggttc
    28741 agaaatactt tgatgagcgt ggtcaggatg aacgcatcag ccatatcgtt gtcatgggaa
    28801 tcggtgagcc ctttgataat tacaacaatg tcttgaattt ctttcgtact atcaatgatg
    28861 ataaaggaat ggctatcggt gctcgtcaca tcacggtttc aacctcaggt ttggctcata
    28921 aaattcgtga ctttgctgat gaaggggttc aggtcaatct tgccgtgtct cttcacgcac
    28981 ctaacaatga acttcgttca agtatcatga agattaaccg tgcctttccg attgaaaaac
    29041 tctttgctgc tattgaatac tacattgaga caacaaaccg tcgtgtaacc tttgaatata
    29101 tcatgcttaa tgaagtcaac gacggtgtag aacaagcctt ggaattgact gaattgctca
    29161 agaacatcaa gaaattgtct tatgtaaact tgattcctta taacccagtt agtgagcatg
    29221 accaatatag ccgtagtccc aaagagtgcg tgttggcttt ctatgatacg cttaagaaaa
    29281 aaggggtcaa ctgtgtggtt cgtcaagagc atggtacaga tattgacgca gcttgtggac
    29341 aattgcgctc taacacaatg aaacgtgacc gccagaaggc agtcgcagcg gtaaatcctt
    29401 aatgatgaag aagacttata atcatatttt ggtctgggga gtcattttct atagcatttg
    29461 cattgtctgt ttttgcttta ctcctcaaga acaatctacc gtgggagtgg gaactccagg
    29521 tattcagcat cttggacgcc tggtttttct tttgactcct ttcaattctc tctggaaact
    29581 gggcgaagtg agtgacattg gacaattatg ttggattttt ttacaaaata tcctcaatgt
    29641 cttcttgttt tttcctctga ttttccaact cctttatcta tttccaaatt tgcggaaaac
    29701 aaaaaaggtc cttcttttta gttttcttgt gagtcttgga atcgagtgta cgcaattaat
    29761 cttggacttt ttctttgatt tcaatcgcgt ctttgagatt gatgatttgt ggaccaacac
    29821 tttgggtggc tatctggctt ggctccttta taaacgatta cataaaaaca aggtaaggaa
    29881 ttaaaatgag tattttagaa gttaaaaatc tgagtcacgg ttttggtgac cgtgcaattt
    29941 ttgaagatgt gtccttccgt ctcctcaagg gagaacatat cggcctggtc ggtgccaatg
    30001 gtgaaggaaa atcaaccttt atgagtatcg tgactggtaa aatgctgcca gatgaaggaa
    30061 aggttgagtg gtccaaatat gtgacggctg gttacttgga tcagcactct gtccttgctg
    30121 aaagacagtc ggtgcgtgat gttctccgta cggcttttga tgagcttttc aaagctgaag
    30181 ctcgtatcaa tgacctctat atgaaaatgg ctgaagacgg cgcggatgtt gatgctctca
    30241 tggaagaagt aggagaactt caagaccgtc tggagagtcg tgatttctat accttggatg
    30301 ctaagattga cgaagtagcg cgtgctcttg gtgttatgga ctttggcatg gatacggatg
    30361 taacttcttt gtcaggtggg caaagaacca aggtgctttt ggcaaaactt ctccttgaaa
    30421 agcctgatat cttgctgttg gacgagccga ccaactactt ggatgctgag catattgatt
    30481 ggctcaagcg ctatctccaa aactatgaga atgcctttgt tctcatttcg cacgatattc
    30541 cattcctcaa tgacgttatt aatattgtct atcatgtgga aaatcaacag ctgacgcgtt
    30601 actctggtga ctactaccag ttccaagaag tttatgctat gaagaaatct cagctagagg
    30661 cagcctacga acgccagcag aaagagattg cagacctcaa ggactttgtg gctcgtaata
    30721 aagcccgtgt tgcaactcgt aatatggcta tgtctcgtca aaagaaattg gataagatgg
    30781 atattatcga actccaaagt gagaaaccaa aaccatcctt tgatttcaaa ccagctcgta
    30841 caccagggcg ctttatcttc caagccaaga acttgcaaat tggttacgac cgtcctctta
    30901 ctaagccttt aaatcttacc ttcgaacgca atcaaaaggt tgcgattatt ggtgctaatg
    30961 gtattggaaa aacaactctc ttgaagagtc tcttgggcat tatctcgcca atcgctgggg
    31021 aagtggagcg tggagattat ttagaacttg gttattttga gcaggaagta gaaggcggta
    31081 atcgccaaac tcctcttgaa gctgtctgga atgcctttcc tgcccttaat caagcagaag
    31141 tccgtgcagc ccttgcccgt tgtggtttga caaccaaaca tattgaaagc cagattcaag
    31201 tattatcagg gggagagcaa gccaaggttc gtttctgtct cttgatgaat cgtgaaaaca
    31261 acgttttagt gctggacgag ccgaccaacc atttggatgt ggatgcaaag gatgagctca
    31321 aacgcgctct caaagaatat aggggatcta tccttatggt ctgccacgag ccagactttt
    31381 atgaaggctg gatagaccaa atatgggatt ttaataattt aacttaagaa tgagagtaaa
    31441 agaaatacag taccgaatgt ggatactgta tttttttggt ttttaagatt taaaatcgta
    31501 gtctttcacc acttcgatgc tgtcgattgt gatagcagta gttggcttgt ctttttcatc
    31561 tttttcggcc ttagcaatct tatccacaac atccataccg tcaatcactt gaccaaagac
    31621 tgggtgtttg ccatctagac tagggtttcc accttctttg taggcttcaa taattttctg
    31681 tggatacttg cttgtaggga gtttagaaga ggtatctgta gagttttggt tgatgaagaa
    31741 ctggctgcca ttggtgtttg gttgaccagt attagccata gcaagagcac cacggatgtt
    31801 atacaaataa ggagtaatct cgttcttgaa accagttcct ttgtctttag tcttatcctt
    31861 gtcatgccag atggactgac cacctgtacc gtcccctttt ggatctccag tttggaccat
    31921 aaagccatcg atgacacggt ggaaggtaat accgttatag tagccttctt tggcgtgagt
    31981 gaggaaattt tcaaccgcta gaggagcgag tttagggaag agtttaatgc gaatatcacc
    32041 ttggcttgtg tggaaaatca cttcggcttc atcttcagca acttccttag atagttgtgg
    32101 gaaattggcg ttttcgtttg ttaaagcatc gtttaactcc ttggcagatt gggcagctac
    32161 tttggaactt tcttcagcag caagactgga atcaacataa tcatcaccac gcagactgcg
    32221 ttggacgctg ctacacccag ctagggctac agtagacagt aaaagaaggg ttgctagttt
    32281 tttcattctg atcctctcaa aaattcattt ataaccattg taccctaaaa ggaagtggat
    32341 ttcaaatatt agtagtttac agaactggct tagataatag ttgggatttc atcatcatct
    32401 tgaaaatctt caacttcttc cccagtaaat ggtttctgaa aagaacttag tataaaacgg
    32461 gcaattggtt caacaattag gaaatttaga ggaagagctg caataaagtt tacgaaccag
    32521 gcgcttagat aggtattggg tgtgatagca atgccattgt aaaaaaagtc catagaagga
    32581 catgaaagtg accagctaat tcttcttctg aaaaatgctc atgaagggct tgatccaggt
    32641 cgcaagattt cattttagaa agtccagtaa ctcccttctt cttcaggata ttctttttca
    32701 tggtattatt tagatggtca agtgagtcaa aagaagtttc gacaagagca tacccttttt
    32761 ctaccagagt ttttagatgt ttaggggcat caataccata agtgtactca aagtattttg
    32821 gaaaccagat cttaagaaag ctcgtaaagc tagccagttc tctaaacgct aagaactagc
    32881 tacaacacag catttacaac acttcatggt tcacaccatg gggtgttttt taatgatttt
    32941 aagcaaaatt cacacttaat tgaaagttat ttaaattaga tgaaaattta ttttttgaaa
    33001 aagtgggaaa acattgattc taagcgaatt ttgaatcata ttcgaatggg agtttttaaa
    33061 atcatgtttc agtggtaaaa gtaccaaact ggattctcca tagtaaaatg atatctcctg
    33121 ctagtgaatc atctactaat aagtccatat ttcgcttggg aacgggcttg ggacttagaa
    33181 gccaagtatc caactctcgt tcaggcgata tgaagggttt gacttggtgt tctttataaa
    33241 atttttctaa aatagtattc acggatagca tctttcaaac atttatttcc tattctaaca
    33301 aatttctaaa tactttaaga aatttatagt ctgtcaagtt tttttcttga cacatgccag
    33361 aaatctgcta taatagaaca tgtgctaaat agctcagcta tttcaccgaa ataaaaaatt
    33421 aaagaaatga gactttaaaa atggcagtta aaatccgttt gactcgtatg ggttctaaga
    33481 aaaaaccttt ctaccgtatc aacgtagcag attcacgttc accacgtgac ggacgtttca
    33541 tcgaaacagt tggaacttac aacccacttg ttgctgaaaa ccaagtaact ttgaaagaag
    33601 accgcgttct tgcatggttg gctaatggag ctcaaccttc agacacagta cgtaacatcc
    33661 tttcaaaaga aggcgtattg aaaaaattcc acgattctaa attttcaaaa taagtttaaa
    33721 gtaggttgac agatggatac gattgaaaat ctcattattg cgattgtgaa acccttaatt
    33781 tcacaaccag atgccttaac tatcaagatt gaggatacac cagaattttt ggaatatcat
    33841 ttgaatcttg atcaaagcga tgtgggtcgt gtaatcggtc gtaagggtcg cactatttct
    33901 gcgataagaa cgattgtcta ctctgtccca actgaataca aaaaagtaag aatcgttatt
    33961 gacgaaaaat aagaagggcg ggacggatgt ctcgcttttt tgtgtggaat agaagatata
    34021 gtaaaatgaa acaagaacag gacaaatcga tcaggacagt caaatcgatt tctaacaatg
    34081 ttttagaagt aaaggtgtac tattctagtt tcaatatact ataaaagatt gaacgtttag
    34141 gcaattccaa gactacttaa tcgaacatta acagcagtct cggactgatg aaggtctctt
    34201 tatgaagtta gtggaggaag tcggagaagt agtcgaggtt ttgaataggc gctctggtcg
    34261 aaaagaaggg ataggattcg aacgaggaac ttgccagaga actggctgat atcatttact
    34321 acaccgtcgc aatcgtagct attaatcata ttgaccttac caagactgtc tttgagaaag
    34381 acaaaaccgc agccattaat taccaacata aacataattt ggaaggatta ttgaagggaa
    34441 agtagagata ttgtcccctt cctccaactt gagaaaatcc ttggaacgtg ataaaataaa
    34501 ggataaggat ttttaataat tcattatata gaatcagtgg atttctttat gaagaggttt
    34561 gaagtatcta cagaaattgg tagcctctct gttacttatc aaaagcaaaa gaaagtgcta
    34621 gtttgtttaa acggagcagg tttgctacca agttatgaaa atttttcact tatacttgaa
    34681 aaacctcctc ctacaattgg ttatttgaca attgattttc cgaacacagg taggagtccg
    34741 attcatgacc aagctggaaa aaatctagat aatcttgcag atgcggttta tgaagtactt
    34801 gaagaattag gaatttctga atatatactt tgtgcacata gttggagtgg aattttagct
    34861 tgcaaattac tcgagaaacc aattaagcgt cagactttag tagcaattga accgacaact
    34921 aaaaaagtca tgtttgctga tttttcagaa aatccttatc cagaaatgga agagcagatg
    34981 aggctgattg acgagtgtgg tcctgaactt tattttaaga acttaactca agcaacattt
    35041 agtcctgaaa cgaataaaaa aatctgggaa ttaatgcaag aaaaaggctt agagttggaa
    35101 aatcaagatc cagaatttca gatatctgga gagattactg aggaagattt tgaggatgta
    35161 tctatagaag ctcatattcc tgtatttgtt ttttgtcagc cttatagaga aaaagagtac
    35221 agagaatcag aatattggac ttccaatact aaactcattt taggagggaa tcaccattat
    35281 ttacaatggt cagaatcgga aaaaattgcg gctattattc gagaattgtt agaataagat
    35341 ggaaaaaagg agattacagg agacaagatg aactacttta atgttgggaa aatcgttaat
    35401 acgcagggat tacaggggga gatgcgagtc ttgtctgtga cggattttgc agaagaacgg
    35461 tttaaaaaag gagctgagct ggttttgttt gatgaaaaag atcagtttgt ccaaacagtg
    35521 accatcgcta gccaccgtaa acagaagaac tttgacatta ttaaattcaa agatatgtac
    35581 catatcaata ctatcgaaaa gtacaaggga tacagtctca aggtcgctga ggaagatttg
    35641 aatgacctag acgatggtga attttactat cacgagatta tcggtttgga agtctatgag
    35701 ggtgatagct tggttggaac catcaaggaa atcctgcaac caggtgctaa tgatgtctgg
    35761 gtggtcaaac gaaaaggcaa acgtgatttg cttttacctt atatcccacc agtggttctc
    35821 aatgttgata ttccaagtaa acgggtcgat gtggaaatct tagaagggtt agacgatgaa
    35881 gattgatatt ttaaccctct ttccagagat gttttctcca ctggagcact caatcgttgg
    35941 aaaggctcga gaaaaagggc tcttggatat ccagtatcat aattttcgag aaaatgctga
    36001 aaaggcccgt catgtagatg atgagcccta cggaggcggt cagggcatgt tgctcagagc
    36061 acaacctatt ttcgattcct ttgatgctat tgaaaagaaa aatccgcgcg ttattctcct
    36121 tgatcctgct ggaaagcagt ttgatcaggc ttatgctgaa gatttggctc aagaggaaga
    36181 gctaatcttt atctgtgggc actatgaggg ttatgatgag cgcattaaga ccttggtaac
    36241 agatgagatt tccctaggtg actatgtcct cactggtgga gaattggcag ctatgaccat
    36301 gattgatgct acagttcgcc tgattccaga agtgattggc aaggagtcta gccaccaaga
    36361 tgatagtttt tcttcaggtc ttttagaata tcctcagtac acacgtccct atgattatcg
    36421 aggcatggtc gtgccagatg tattgatgag tggccaccat gaaaagattc gtcagtggcg
    36481 attgtacgag agtttaaaga aaacctacga gcgcagaccg gatttacttg aacattatca
    36541 actgacagta gaagaagaaa aaatgctggc agaaatcaaa gaaaacaaag aataaaggag
    36601 aaacctatgc aagtaatcaa acgtaatggc gaaattgctg aatttaatcc agataagatt
    36661 taccaagcca tcttgaaggc agcccaaact gtttatgttt tgacagatga tttgcgtcaa
    36721 aatcttgctc aagtcactaa gaaggtagtt ttggatttac aagaagccaa ggtggaacgt
    36781 gcgactatca gtatgattca atctatggtt gaacatcgtt tattgggcgc aggttacatt
    36841 accattgcag aacactacat ttcctatcgt ttacaacgtg acttggaaag aagtggttat
    36901 ggagatcata tcgcagttca tttacatttt gaacaaattc gctaagaaaa aagagtggga
    36961 tgaagcaact acatctcact ctttcttaaa tctatttttt tgggctgttt ggacagttga
    37021 ggggacaaat cgcaggcgtt gaatatcgct tatacggata atccggctca catttttgga
    37081 aaaatttttc acgataattt gctggccttg ctgatcatat ttgatgatgt cacctgtaaa
    37141 gcttgtctca gacaagataa ggtgaacagc ggtttgtttc tggatagcct cttcaatagt
    37201 ggctgtaagg gagttggttt cagtctggtc aggttggtca tatccattta aaaaatcatg
    37261 tattttattt agaacttgct ggaatttatg tctcatattg gcctcccttc ttttatatca
    37321 atattatata aaattttcct aaaatctaca agattttacg aataaactaa tgaaactaaa
    37381 aaaggagaag aaaatggcag aatttacatt tgaaatcgaa gagcacttgt tgactctttc
    37441 tgaaaacgaa aaaggttgga ccaaggaaat taaccgtgtg agctttaatg gtgcccctgc
    37501 aaagtttgat attcgtgctt ggagtccaga ccatactaaa atgggcaaag ggattactct
    37561 ctcaaatgaa gaatttcaaa cgatggtgga tgcctttaaa ggcaactaat actcttcgaa
    37621 aatctcttca aaccgcgtca gctttgcctt gccgtatgta tggttactga cttcgtcagt
    37681 ttcatccaca acctcaaaac agtgttttga gcagcctgcg gctagcttcc tagtttgctc
    37741 tttgattttc attgagtata agttttcaaa ataaaagaaa aggatattga gtcatgataa
    37801 ctcgatatcc ttttttagtt agtaaagtaa gcctgatttt taaggcgttg aagtagggga
    37861 cggctaataa aactaatagc tagaagtttg ccaaggtctg gaatgataaa gggaagaacc
    37921 cccacagcaa gagctttttc aaatgccatt ccagctagga aatgcaagct gagaatcccg
    37981 ccgacaaaga caagggcatc acccaagagg tttgcaagaa aaatcttaac aacaccactc
    38041 ttgctgttgg ttagagagga agtaagtcca gagtaaacga gataaaacca aagatagcct
    38101 gcagtagggc caactaaagc ctgaaaacca gctccacctc ctgcaaagac aggaagaccg
    38161 atagcaccta gaagaagata gagtccagca gaaagtacag cctctctcgg tctaaagaca
    38221 gtagcaatca agccgattgc aaagttttgc agagtgaagg gaacaggtcc aattggaaga
    38281 ctgatttgtg ccaaagcagc aatgagagca gccccaatag cagggatagc ataaacgtga
    38341 gcttttttca aaatagttaa cctcttttct aatgtatagt aactattata ctcatatagg
    38401 agtcgatgtc aaccattttt taaaaacaag gtaacaaaaa ctgtaacagc cgattttcgt
    38461 gactagtcaa gttggataat ttttttgttg attcgaaaat cattaaaaaa gaagcagaca
    38521 tatttatatc agcttctttt gtttcgatta acgcatggtt acaaattctt cagatgcagt
    38581 tgggtgaatt gccacagttg catcaaagtc agccttggtt gctcccattt tgatagcaac
    38641 ggcaaatccc tgaatcattt catcaacgcc gtagccaatt ccatgaagtc cgacaacttt
    38701 ttcttctgaa ccagctgtta tgagtttgaa acgggattct tgacggttgc gagtgcaagc
    38761 agagtacata gatgcaaagc ttgatttata aaccttgatt tggtcttgac cgtattcttt
    38821 aatagcttgc tcttctgtca aaccaacagt tccgatagca gggtgtgaaa agacaacagt
    38881 tggaatagtt gagtaatcca tttttgcagt agtttttccg ttaaagagac gttcagatag
    38941 ggtacgtccg gccttgattg caactggagt cagttctttc tcgcccgtta catcacctag
    39001 agcatagatt ccctcaacaa cagtattttg gtattcatcc acttggataa agccacgttc
    39061 gttcagagtc actccagctt tttcaagttg caagccctta acgtttggac ggcgacctgt
    39121 agcccagata acttggctag ctgtgtgact agtaccatct tcgaaatgaa tggtaatgcc
    39181 gtcagtagtt ttttctaact tgacagggac tttgtgagtg tgaagtggta agtttgttct
    39241 ttccatttcc ttgaccaaac cttcaacgat gtaggaatca aaaccacgta aaggacgatc
    39301 gcggcgaaca aagagatctg tcttgacacc aaaagtgtgg agtacgccag ctaattcaac
    39361 ggcgatataa ccagcgccta gaatggcaat tgactctgga agttcttccc aggcaaatac
    39421 atcatcagaa gagccaccta gctcagcacc aggaatatta ggaatacttg gatgggcacc
    39481 tgtagcaatc acgatatgtt tagcacgaat cagttcacca tttacgctta cagtatgaga
    39541 atctacaaat tcagcatgac cttcaatcaa gtctacaccg ttgcgtttaa aactaccatc
    39601 ataagaagaa cgagcgcgat caatgtaggc ttcacgattg cgacgtaggg ttgcaaagtc
    39661 aaagttaaga tcagtagtct taaagccgta gtcttctcca aattgatgga aagtctcagc
    39721 gatttgcgcc ccgtaccaca tgattttttt aggaacacaa ccgacgttga cacaggttcc
    39781 acctaatttc ttttcctcaa taacggctgc tttggctcca tgttcaccag cacggttcat
    39841 ggtagcgatt cctccgctac ctccaccgat agcaatgata tcatattctc tcattgaaaa
    39901 ctcctttgta atcttttaaa tagtagagcg tcttttttga tagttatatt ttattctttt
    39961 tttgatttga ttgcaaaaat ctgctacgca caaaaaattg caaaaaagct tgccaaataa
    40021 gtcaagatag tgtattatat atctagtaca atagaaaagc aaaattccga acgattgttt
    40081 aatcctgaac tgtattgttt gctggaggga aatttggtat aatagcaaag tattgtaaaa
    40141 aagaaaagga gtttcattat gaagaaaaag aatggtaaag ctaaaaagtg gcaactgtat
    40201 gcagcaatcg gtgctgcgag tgtagttgta ttgggtgctg gggggatttt actctttaga
    40261 caaccttctc agactgctct aaaagatgag cctactcatc ttgttgttgc caaggaagga
    40321 agcgtggcct cctctgtttt attgtcaggg acagtaacag caaaaaatga acaatatgtt
    40381 tattttgatg ctagtaaggg tgatttagat gaaatccttg tttctgtggg cgataaggtc
    40441 agcgaagggc aggctttagt caagtacagt agttcagaag cgcaggcggc ctatgattca
    40501 gctagtcgag cagtagctag ggcagatcgt catatcaatg aactcaatca agcacgaaat
    40561 gaagccgctt cagctccggc tccacagtta ccagcgccag taggaggaga agatgcaacg
    40621 gtgcaaagcc caactccagt ggctggaaat tctgttgctt ctattgacgc tcaattgggt
    40681 gatgcccgtg atgcgcgtgc agatgctgcg gcgcaattaa gcaaggctca aagtcaattg
    40741 gatgcaacaa ctgttctcag taccctagag ggaactgtgg tcgaagtcaa tagcaatgtt
    40801 tctaaatctc caacaggggc gagtcaagtt atggttcata ttgtcagcaa tgaaaattta
    40861 caagtcaagg gagaattgtc tgagtacaat ctagccaacc tttctgtagg tcaagaagta
    40921 agctttactt ctaaagtgta tcctgataaa aaatggactg ggaaattaag ctatatttct
    40981 gactatccta aaaacaatgg tgaagcagct agtccagcag ccgggaataa tacaggttct
    41041 aaataccctt atactattga tgtgacaggc gaggttggtg atttgaaaca aggtttttct
    41101 gtcaacattg aggttaaaag caaaactaag gctattcttg ttcctgttag cagtctagta
    41161 atggatgata gtaaaaatta tgtctggatt gtggatgaac aacaaaaggc taaaaaagtt
    41221 gaggtttcat tgggaaatgc tgacgcagaa aatcaagaaa tcacttctgg tttaacgaac
    41281 ggtgctaagg tcatcagtaa tccaacatct tccttggaag aaggaaaaga ggtgaaggct
    41341 gatgaagcaa ctaattagtc taaaaaatat cttcagaagt taccgtaatg gtgaccaaga
    41401 actgcaggtt ctcaaaaata tcaatctaga agtgaatgag ggtgaatttg tagccatcat
    41461 gggaccatct gggtctggta agtccactct gatgaatacg attggcatgt tggatacacc
    41521 aaccagtgga gaatattatc ttgaaggtca agaagtggct gggcttggtg aaaaacaact
    41581 agctaaggtc cgtaaccaac aaatcggttt tgtctttcag cagttctttc ttctatcgaa
    41641 gctcaatgct ctgcaaaatg tagaattgcc cttgatttac gcaggagttt cgtcttcaaa
    41701 acgtcgcaag ttggctgagg aatatttaga caaggttgaa ttgacagaac gtagtcacca
    41761 tttaccttca gaattatctg gtggtcaaaa gcaacgtgta gccattgcgc gtgccttggt
    41821 aaacaatcct tctattatcc tagcggatga accgacagga gccttggata ccaaaacagg
    41881 taaccaaatt atgcaattat tggttgattt gaataaagaa ggaaaaacca ttatcatggt
    41941 aacgcatgag cctgagattg ctgcctatgc caaacgtcag attgtcattc gggatggggt
    42001 catttcgtct gacagtgctc agttaggaaa ggaggaaaac taagatgcag aatctgaaat
    42061 ttgccttttc atctatcatg gctcacaaga tgcgttcttt gcttactatg attgggatta
    42121 ttatcggtgt ttcatcagtt gttgtgatta tggctttggg tgattcccta tctcgtcaag
    42181 tcaataaaga tatgactaaa tctcagaaaa atattagcgt ctttttctct cctaaaaaaa
    42241 gtaaagacgg gtcttttact cagaaacaat cagcttttac ggtttctgga aaggaagagg
    42301 aagttcctgt tgaaccgcca aaaccgcaag aatcctgggt ccaagaggca gctaaactga
    42361 agggagtgga tagttactat gtaaccaatt caacgaatgc catcttgacc tatcaagata
    42421 aaaaggttga gaatgctaat ttgacaggtg gaaacagaac ttacatggac gctgttaaga
    42481 atgaaattat tgcaggtcgt agtctgagag agcaagattt caaagagttt gcaagtgtca
    42541 ttttgctaga tgaggaattg tccattagtt tatttgaatc tcctcaagag gctattaaca
    42601 aggttgtaga agtcaatgga tttagttacc gggtcattgg ggtttatact agtccggagg
    42661 ctaaaagatc aaaaatatat gggtttggtg gcttgcctat tactaccaat atctcccttg
    42721 ctgcgaattt taatgtagat gaaatagcta atattgtctt tcgagtgaat gataccagtt
    42781 taaccccaac tctgggtcca gaactggcac gaaaaatgac agagcttgca ggcttacaac
    42841 agggagaata ccaggtggca gatgagtccg ttgtatttgc agaaattcaa caatcgttta
    42901 gttttatgac gacgattatt agttccatcg cagggatttc tctctttgtt ggaggaactg
    42961 gtgtcatgaa catcatgctg gtttcggtga cagagcgcac tcgtgagatt ggtcttcgta
    43021 aggctttggg tgcaacacgt gccaatattt taattcagtt tttgattgaa tccatgattt
    43081 tgaccttgtt aggtggctta attggcttga caattgcaag tggtttaact gccttagcag
    43141 gtttgttact gcaaggttta atagaaggta tagaagttgg agtatcaatc ccagtcgccc
    43201 tatttagtct tgcagtttcg gctagtgttg gtatgatttt tggagtcttg ccagccaaca
    43261 aggcatcgaa acttgatcca attgaagccc ttcgttatga atgagatcaa caagatggac
    43321 actcgtctat cttgtttttg tatggatttc cctattgaaa ttcattaaaa atgtgatata
    43381 atgaagtgtt agaaaaacag gtttcatttg cctggaaagg aaaaattatg tctgaaaaaa
    43441 atttttatat tacaacgccg atttactatc catctgggaa acttcatatc ggttctgcct
    43501 acacaactat cgcatgtgat gtcctagcac gttacaaacg cctgatgggc tacgatgtat
    43561 tttatctgac aggtcttgat gaacatggtc agaaaatcca gcagaaagcg gaagaagctg
    43621 gtattacacc tcaagcctat gttgatggaa tggcggttgg agttaaagaa ctctggcaat
    43681 tactagatat ctcatacgat aaatttatcc gtacaactga tgactaccat gaaaaagttg
    43741 tcgcacaagt ctttgaacgc ttacttgctc aagatgatat ctacttgggt gaatactctg
    43801 gttggtattc agtatcagac gaagaattct ttacagaaag ccagctggca gaagttttcc
    43861 gtgatgaagc tggaaatgtg actggtggta ttgctccatc aggtcatgag gttgaatggg
    43921 tttctgaaga atcatacttc cttcgcctta gcaaatacca agaccgtttg gtcgaatttt
    43981 tcaaagctca tcctgaattt atcacgccag atggtcgcct taatgaaatg ctacgcaact
    44041 tcatcgagcc aggcttggaa gatttggcgg tatctcgtac aacctttaca tggggagtgc
    44101 ctgtcccatc aaatccaaaa cacgttgtct acgtttggat tgatgccctt cttaactatg
    44161 cgacagctct tggctacgct caagacgaac atggtaactt tgacaagttc tggaatggaa
    44221 cagtcttcca tatggtagga aaagatatcc ttcgcttcca ctctatctac tggccaatcc
    44281 ttcttatgat gttggatgtt aaattacctg atcgtttgat tgcccatggt tggtttgtca
    44341 tgaaagacgg aaaaatgtct aagtcaaaag ggaatgtcgt ttaccctgaa atgttggtag
    44401 agcgttatgg actagatcca cttcgttact acctcatgcg taaccttcca gttggttcag
    44461 acggaacctt tactcctgaa gactatgtcg gccgtatcaa ctatgaattg gctaatgacc
    44521 ttgggaacct ccttaaccgt acggtttcca tgattaataa gtactttgat ggacaaatcc
    44581 ctgcctatgt agaaggtgtg actgaatttg atcatgttct tgctgaggtt gcagaacaat
    44641 caatcgcaga cttccataca cacatggaag cagttgacta tccacgtgcg cttgaagcag
    44701 tctggactct gatctctcgt accaataaat acatcgatga gaccgcacca tgggtcttgg
    44761 ccaaggatga agctcttcgt gaccaattgg caagtgtcat gagccacttg gcagccagca
    44821 ttcgtgtagt tgctcacttg attgaaccat ttatgatgga aactagtcgt gcagttttga
    44881 ctcaacttgg tttggaagaa gtttctagtc ttgaaaactt gagtttggct gacttcccag
    44941 cagatgtgac tgtagttgcc aaaggaacac ctatctttcc acgtctaaat atggaagaag
    45001 aaatcgccta tatcaaggaa caaatggaag gcaataaacc agcagtcgaa aaagaatgga
    45061 atccggacga agttgagctc aaactaaaca aggatgaaat caagtttgaa gactttgaca
    45121 aggttgaaat ccgtgtcgca gaagtcaaag aagtgtctaa agtagaaggt tcagataagt
    45181 tgcttcaatt ccgcttggat gctggtgatg gagaagatcg tcagattctt tcaggaattg
    45241 caaaatacta tccaaatgaa caagaattgg tcggcaagaa agttcaaatc gttgctaacc
    45301 tcaaaccacg taaaatgatg aaaaaatatg tcagccaggg tatgattctc tcagctgaac
    45361 atgatggcaa attaaccctt ctcacagttg atccagctgt accaaatgga agtgtgattg
    45421 ggtaaaagta gacaggacta gttcaggcta gttctgtttt tttatttata ctcaatgaaa
    45481 atcaaagagc aaactaggaa gctagccgca ggttgctcaa aacactgttt tgaggttgta
    45541 gacgaaactg acgaagtcag ctcaaaacat gtttttgagg ttgtagatga aactgacgaa
    45601 g
//
LOCUS       DAVFER010000016        44615 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1105170250
            SAMEA2167659-rid19724873.denovo.016, whole genome shotgun sequence.
ACCESSION   DAVFER010000016 DAVFER010000000
VERSION     DAVFER010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2167659
            Sequence Read Archive: ERR388902
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 44615)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 44615)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928716.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928716.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 04:07:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,118
            CDSs (total)                      :: 2,073
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 120
            CDSs (without protein)            :: 120
            Pseudo Genes (ambiguous residues) :: 0 of 120
            Pseudo Genes (frameshifted)       :: 67 of 120
            Pseudo Genes (incomplete)         :: 47 of 120
            Pseudo Genes (internal stop)      :: 34 of 120
            Pseudo Genes (multiple problems)  :: 23 of 120
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..44615
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2167659-rid19724873.denovo.016"
                     /strain="1105170250"
                     /db_xref="taxon:1313"
     gene            144..1352
                     /locus_tag="VU534_000891"
     CDS             144..1352
                     /locus_tag="VU534_000891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEU1513501.1"
                     /translation="MNYIKRPHYLDFLRKHRDRPIIKVVSGVRRAGKSVLFQLYKEEL
                     LATGVDEDQIIFINFEDLSYYDLRHFQTLFAYIKDQLVSKKTYYIFLDEIQYVEKFEL
                     VADSLFILANVDLYLTGSNAYFMSSQLATNLTGRYVEIEVLPLSFEEYLSGQSLTENL
                     NTTEIFNNYLFSAFPYLLQTSSYDEKIDYLRGIYNSILLNDIVTRLGKPNPTIIERIV
                     RTLLSSTGSLISTNKIRNTLVSQNVSISHNTLENYLTTLTDSLLFYSVPRFDVKGRAL
                     LQRLEKYYPVDLGLRHLLLPDQKEDIRHILENMVYLELRRRYSQVYVGNLDKYEVDFV
                     VVTDLGHYAYYQVSETTLAPETLERELRPLEAIKDQFPKYLLTMDTIQPTANYNGIEK
                     KSIIDWLLEK"
     gene            1728..2132
                     /locus_tag="VU534_000892"
     CDS             1728..2132
                     /locus_tag="VU534_000892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEU1513502.1"
                     /translation="MLFFSISNDLLQLLTSWEKQQRYELAKFGILSNPEQFVFTYIDT
                     KGNINKPLHADYLNNKMKSIRKRHKELTHATPHKLRHTGATLAKKAGMSLEAISEALT
                     HSDTVTTKTYVNTSNIVPLSAGQVAYQHLKNK"
     gene            complement(2395..2787)
                     /gene="rpsI"
                     /locus_tag="VU534_000893"
     CDS             complement(2395..2787)
                     /gene="rpsI"
                     /locus_tag="VU534_000893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HEU1513503.1"
                     /translation="MSQAQYAGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADL
                     RLVINQPFAVTSTVGSYDVFVNVIGGGYAGQSGAIRHGIARALLQVDPDFRDSLKRAG
                     LLTRDSRKVERKKPGLKKARKASQFSKR"
     gene            complement(2806..3252)
                     /gene="rplM"
                     /locus_tag="VU534_000894"
     CDS             complement(2806..3252)
                     /gene="rplM"
                     /locus_tag="VU534_000894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HEU1513504.1"
                     /translation="MNKTTFMAKPGQVERKWYVVDATDVPLGRLSAVVASVLRGKNKP
                     TFTPHTDTGDFVIVINAEKVKLTGKKATDKIYYTHSNHPGGLKQISAGELRSKNAVRL
                     IEKSVKGMLPHNTLGRAQGMKLKVFVGAEHTHAAQQPEVLDISGLI"
     gene            3608..3925
                     /locus_tag="VU534_000895"
     CDS             3608..3925
                     /locus_tag="VU534_000895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HEU1513505.1"
                     /translation="MAFTNTHMRSASFGIVTSLPDDIIDSFWYIIDHFLKNVFELEEE
                     LEFQLLNNQGKITFHFSSQHLPTAIDFDFNHPFDPRYPPRVLVLDMDGRETILLPEEN
                     DLF"
     gene            complement(4075..4887)
                     /gene="folK"
                     /locus_tag="VU534_000896"
     CDS             complement(4075..4887)
                     /gene="folK"
                     /locus_tag="VU534_000896"
                     /EC_number="2.7.6.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-amino-4-hydroxy-6-
                     hydroxymethyldihydropteridine diphosphokinase"
                     /protein_id="HEU1513506.1"
                     /translation="MDQLQIKDLEMFAYHGLFPSEKELGQKFVVSAILSYDMTKAATD
                     LDLTASVHYGELCQQWTTWFQETSEDLIETVAYKLVERTFEFYPLVQEMKLELKKPWA
                     PVHLSLDTCSVTIHRRKQRAFIALGSNMGDKQANLKQAIDKLRARGIHILKESSVLAT
                     EPWGGVEQDSFANQVVEVETWLPAQDLLETLLAIESELGRVREVHWGPRLIDLDLLFV
                     EDQILYTDDLILPHPYIAERLFVLESLQEIAPHFIHPILKQPIRNLYDALKK"
     gene            complement(4930..5484)
                     /gene="folE"
                     /locus_tag="VU534_000897"
     CDS             complement(4930..5484)
                     /gene="folE"
                     /locus_tag="VU534_000897"
                     /EC_number="3.5.4.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP cyclohydrolase I FolE"
                     /protein_id="HEU1513507.1"
                     /translation="MDTQKIEAAVKMIIEAVGEDANREGLQETPARVARMYQEIFSGL
                     GQTAEEHLSKSFEIIDDNMVVEKDIFFHTMCEHHFLPFYGRAHIAYIPDGRVAGLSKL
                     ARTVEVYSKKPQIQERLNIEVADALMDYLGAKGAFVVIEAEHMCMSMRGVRKPGTATL
                     TTVARGLFETDKDLRDQAYRLMGL"
     gene            complement(5465..6787)
                     /locus_tag="VU534_000898"
     CDS             complement(5465..6787)
                     /locus_tag="VU534_000898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000658404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HEU1513508.1"
                     /translation="MKEIENNQWIANYRTDQPHFGLERMVELLALRGNPHLKLKVLHI
                     GGTNGKGSTIAFLKKMLEKLGLRVGVFSSPYLIHYTDQISINGESISEARLEALMADY
                     QSLLEGEAVANLQGTTEFEIITALAYDYFASEQVDVAIMEVGMGGLLDSTNVCQPILT
                     GITTIGLDHVALLGDTLEVIAEQKAGIIKQGMPLVTGRIAPEALAVIDRIAEGKDAPR
                     LAYGTDYQVRHQESVVTGEVFDYTSAVRQGRFQTSLLGLYQIENAGMAIALLDTFCQE
                     DGRELASNDFLGQALEETSWPGRLEIVSRDPLMILDGAHNPHAIKALLVTLQERFADY
                     HKEILFTCIKTKALEDMLDLLGAMPVTELTLTHFADSRATDENVLKEAAKSRNLSYQD
                     WHDFLEQNLTDKKEEKQTVRIVTGSLYFLSQVRAYLMERKNENGYTKD"
     gene            complement(6789..7763)
                     /gene="folP"
                     /locus_tag="VU534_000899"
     CDS             complement(6789..7763)
                     /gene="folP"
                     /locus_tag="VU534_000899"
                     /EC_number="2.5.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteroate synthase"
                     /protein_id="HEU1513509.1"
                     /translation="MMKILEGVTDMSSKANHAKTVICGIINVTPDSFSDGGQFFALEQ
                     ALQQARKLIAEGASMLDIGGESTRPGSSYVEIEEEIQRVVPVIKAIRKESDVLISIDT
                     WKSQVAEAALAAGADLVNDITGLMGDEKMAYVVAEARAKVVIMFNPVMARPQHPSSLI
                     FPHFGFGQTFTEKELADFETLPIEDLMVAFFERALARAAEAGIAPENILLDPGIGFGL
                     TKKENLLLLRDLDKLHQKGYPIFLGVSRKRFVINILEENGFEVNPETELGFRNRDTAS
                     AHVTSIAARQGVEVVRVHDVASHRMAVEIASAIRLADEAENLDLKQYK"
     gene            complement(7858..8565)
                     /locus_tag="VU534_000900"
     CDS             complement(7858..8565)
                     /locus_tag="VU534_000900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU1513510.1"
                     /translation="MKEKNMWKELLNRAGWILVFLLAVLLYQVPLVVTSILTLKEVAL
                     LQSGLIVAGLSIVVLALFIMGARKTKLASFNFSFFRAKDLARLGLSYLVIVGSNILGS
                     ILLQLSNETTTANQSQINDMVQNSSLISSFFLLALLAPICEEILCRGIVPKKIFRGKE
                     NLGFVVGTIVFALLHQPSNLPSLLIYGGMSTVLSWTAYKTQRLEMSILLHMIVNGIAF
                     CLLALVVIMSRTLGISV"
     gene            complement(8618..10036)
                     /locus_tag="VU534_000901"
     CDS             complement(8618..10036)
                     /locus_tag="VU534_000901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HEU1513511.1"
                     /translation="MDKLFKLKENGTDVRTEVLAGLTTFFAMSYILFVNPQILSQTGM
                     PAQGVFLATIIGAVAGTLMMAFYANLPYAQAPGMGLNAFFTFTVVFGLGYSWQEALAM
                     VFICGIISLIITLTNVRKMIIESIPNALRSAISAGIGVFLAYVGIKNAGLLKFTIDPG
                     NYTVVGEGADKAQATIAANSSAVPGLVSFNNPAVLVALAGLAITIFFVIKGIKGGIIL
                     SILTTTVLAIAVGLVDLSSIDFANNHVGAAFEDLKTIFGAALGSEGLGALVSDTARLP
                     ETLMAILAFSLTDIFDTIGTLIGTGEKVGIVATNGENHQSAKLDKALYSDLIGTTVGA
                     IAGTSNVTTYVESAAGIGAGGRTGLTALVVAICFAISSFFSPLLAIVPTAATAPILII
                     VGIMMLGSLKNIHWDDMSEAVPAFFTSIFMGFSYSITQGIAVGFLTYTLTKLVKGQVK
                     DVHVMIWILDALFILNYISMAL"
     gene            10226..11038
                     /locus_tag="VU534_000902"
     CDS             10226..11038
                     /locus_tag="VU534_000902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000162344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEU1513512.1"
                     /translation="MTKKIIAVDLDGTLLNSDSQISDFTKRTIKKVAEKGHQVIITTG
                     RPYRMSKDFYRELGLDTPMINFNGSLTHLPDQVWDFEKCLTVDKKYLLDMVQRSEDIQ
                     ADFIAGEYRKKFYITNPNEEIANPKLFGVEAFQPEDQFQPELVTKDPNCILLQTRASD
                     KYSLAKEMNAFYQHQLSINTWGGPLNILECTPKGVNKAFALDYLLKIMNRDKKDLIAF
                     GDEHNDTEMLAFAGKGYAMKNANPELLPYADEQISLTNDQDGVAKTLQDLFL"
     gene            11378..12397
                     /gene="adhP"
                     /locus_tag="VU534_000903"
     CDS             11378..12397
                     /gene="adhP"
                     /locus_tag="VU534_000903"
                     /EC_number="1.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase AdhP"
                     /protein_id="HEU1513513.1"
                     /translation="MKAVVVNPESTGVAIEEKVLRPLETGEALVEVEYCGVCHTDLHV
                     AHGDFGQVPGRVLGHEGIGIVKEIAPDVKSLKVGDRVSVAWFFEGCGTCEYCTTGRET
                     LCRTVKNAGYSVDGGMAEQCIVTADYAVKVPDGLDPAQASSITCAGVTTYKAIKEAKV
                     EPGQWVVLYGAGGLGNLAVQYAKKVFNAHVIAVDINNDKLALAKEVGADIVINGLEVE
                     DVAGLIKEKTDGGAHSAVVTAVSKVAFNQAVDSIRAGGRVVAVGLPSEMMELSIVKTV
                     LDGIQVIGSLVGTRKDLEEAFQFGAEGLVVPVVQKRPVEDAVAIFDEMEKGQIQGRMV
                     LDFTH"
     gene            12630..13619
                     /gene="manX"
                     /locus_tag="VU534_000904"
     CDS             12630..13619
                     /gene="manX"
                     /locus_tag="VU534_000904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000021981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIAB"
                     /protein_id="HEU1513514.1"
                     /translation="MSIGIIIASHGEFAAGIHQSGSMIFGEQEKVQVVTFMPNEGPDD
                     LYAKFNNAVAAFDAEDEVLVLADLWSGSPFNQASRVMGENPERKFAIITGLNLPMLIQ
                     AYTERLMDAAAGVEKVAANIIKEAKDGIKALPEELNPVEEVASAAAAPVAQTAIPEGT
                     VIGDGKLKINLARLDTRLLHGQVATAWTPDSKANRIIVASDNVAKDDLRKELIKQAAP
                     GNVKANVVPIQKLIEISKDPRFGETHALILFETPQDALRAIEGGVPIKTLNVGSMAHS
                     TGKTLVNTVLSMDKEDVATFEKMRDLGVEFDVRKVPNDSKKDLFDLINKANVK"
     gene            13647..14450
                     /locus_tag="VU534_000905"
     CDS             13647..14450
                     /locus_tag="VU534_000905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HEU1513515.1"
                     /translation="MSIISMVLVVVVAFFAGLEGILDQFQFHQPLVACTLIGLVTGHL
                     EAGIILGGSLQMIALGWSNIGAAIAPDAALASVAAAIIMVLGGDFTKTGIGVAQAVAI
                     PLAVAGLFLTMIVRTISVGLVHTADAAAKKGDFGAVERAHFIALLFQGLRIALPAALL
                     LMVPTETVQSILSAMPDWLKDGMAIGGGMVVAVGYAMVINMMATREVWPFFALGFVLA
                     AVSDITLIGFGAIGVAIALIYLHLSKTGGNGGGGAATSNDPIGDILEDY"
     gene            14474..15385
                     /locus_tag="VU534_000906"
     CDS             14474..15385
                     /locus_tag="VU534_000906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEU1513516.1"
                     /translation="MTEKLQLTKSDRKKVWWRSTFLQGSWNFERMQNLGWAYTLIPAI
                     KKLYTKKEDQIAALERHLEFFNTHPYVAAPVMGVTLALEEERANGVEIDDAAIQGVKI
                     GMMGPLAGIGDPVFWFTVRPILGSLGASLALTGNILGPLLFFVAWNLIRMSFLWYVQE
                     IGYKAGSEITKDMSGGILQDITKGASILGMFILAVLVQRWVNIKFAFDVSKVQLDEKA
                     YIHWDKLPEGSKGIQEAFAQVGQGLSQTPEKVTTFQQNLDMLIPGLSGLLLTLLCMYL
                     LKKKVSPITIILALFAVGIVAHVLHIM"
     gene            complement(15441..16775)
                     /gene="pepC"
                     /locus_tag="VU534_000907"
     CDS             complement(15441..16775)
                     /gene="pepC"
                     /locus_tag="VU534_000907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000991632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase C"
                     /protein_id="HEU1513517.1"
                     /translation="MNAIQESFTDKLFANYEANVKYQAIENAASHNGIFAALERRQSH
                     VDNTPVFSLDLTKDKVTNQKASGRCWMFAALNTFRHKLISQYKLENFELSQAHTFFWD
                     KYEKSNWFLEQVIATSDQELTSRKVSFLLQTPQQDGGQWDMVVSLFEKYGVVPKSVYP
                     ESVSSSSSRELNAILNKLLRQDAQILRDLLVSGADQATVQAKKEDLLQEIFNFLAMSL
                     GLPPRKFDFAYRDKDNNYKSEKGITPQEFYKKYVNLPLEDYVSVINAPTADKPYGKSY
                     TVEMLGNVVGSRAVRYINVPMERLKELAIAQMQAGETVWFGSDVGQLSNRKAGILATD
                     VYDFESSMDIKLTQDKAGRLDYSESLMTHAMVLTGVDLDENGKSTKWKVENSWGDKVG
                     TDGYFVASDAWMDEYTYQIVVRKELLTAEEQAAYGAEPIVLAPWDPMGALAE"
     gene            complement(16993..17715)
                     /locus_tag="VU534_000908"
     CDS             complement(16993..17715)
                     /locus_tag="VU534_000908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HEU1513518.1"
                     /translation="MRLDKFLVACAVGSRTEVKNLLKAGRVTVNGKKEKSAKLQIDEK
                     IDEIRFDGQVLEYEEFVYYMMNKPKGVISATEDPKHRTVLDLLDDLARSKEVFPVGRL
                     DIDTHGLLLLTNDGQLAHVLLSPKRHVDKTYLAQVKGIMTQEDVETFAEGIPLKDFTC
                     QPAILELVSIDTEKNQSQIRVTIAEGKFHQIKRMVGYCGKEVVDLQRLTMGTLVLDEN
                     LERGEWRRLTKEELEILRANII"
     gene            complement(17983..18213)
                     /locus_tag="VU534_000909"
     CDS             complement(17983..18213)
                     /locus_tag="VU534_000909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000901571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HEU1513519.1"
                     /translation="MLGSMFVGLLVGFLAGAMTNRGERMGCFGKMFLGWIGAFLGHLL
                     FGTWGPVLSGTAIIPAILGAMIVLAIFWRRGS"
     gene            complement(18223..19464)
                     /locus_tag="VU534_000910"
     CDS             complement(18223..19464)
                     /locus_tag="VU534_000910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000243957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HEU1513520.1"
                     /translation="MVLPNFKENLEKYAKLLVANGINVQPGHTLALSIDVEQRELAHL
                     IVKEAYALGAHEVIVQWTDDVINREKFLHAPMERLDNVPEYKIAEMNYLLENKASRLG
                     VRSSDPGALNGVDADKLSASAKAMGLAMKPMRIATQSNKVSWTVAAAAGLEWAKKVFP
                     NAASDEEAVDFLWDQIFKTCRVYEADPVKAWEEHAAILKSKADMLNKEQFSALHYTAP
                     GTDLTLGLPKNHVWESAGAVNAQGEEFLPNMPTEEVFTAPDFRRADGYVTSTKPLSYN
                     GNIIEGIKVTFKDGQIVDITAEKGDQVMKDLVFENAGARALGECALVPDPSPISQSGI
                     TFFNTLFDENASNHLAIGAAYATSVVDGAEMSEEELEAAGLNRSDVHVDFMIGSNQMD
                     IDGIREDGTRVPLFRNGNWAN"
     gene            complement(19486..19638)
                     /locus_tag="VU534_000911"
     CDS             complement(19486..19638)
                     /locus_tag="VU534_000911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000776615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1513521.1"
                     /translation="MKLRIFAEDKPAKKVFEYQLELADRTILLSTALLSGAIALAGIF
                     SALKEK"
     gene            complement(19659..19937)
                     /locus_tag="VU534_000912"
     CDS             complement(19659..19937)
                     /locus_tag="VU534_000912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013904578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system YafQ family
                     toxin"
                     /protein_id="HEU1513522.1"
                     /translation="MLKIRYHKQFKKDFKLAMKRGLKAELLEEVLNFLVQEKEHPARN
                     RDHSLTASKHFQGVRECHTQPDWLLVYKVDKSELILNLLRTGSHSDLF"
     gene            complement(19930..20193)
                     /locus_tag="VU534_000913"
     CDS             complement(19930..20193)
                     /locus_tag="VU534_000913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HEU1513523.1"
                     /translation="MSKMSISIRLDSEVKEQAQQVFSNLGMDMTTAINIFLRQAIQYQ
                     GLPFDVRLDENRKLLQALTDLDQNRNMSQSFESVSDLMEDLRA"
     gene            complement(20295..24686)
                     /locus_tag="VU534_000914"
     CDS             complement(20295..24686)
                     /locus_tag="VU534_000914"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HEU1513524.1"
                     /translation="MSNSFEILMNQLGMPAEMRQAPALAQANIERVVVHKISKVWEFH
                     FVFSNILPIEIFLELKKGLSEEFSKTGNKAVFEIKARSQEFSNQLLQSYYREAFSEGP
                     CASQGFKSLYQNLQVRAEGNQLFIEGSEAIDKEHFKKNHLPNLAKQLEKFGFPTFNCQ
                     VEKNDVLTQEQEEAFHAENEQIVQAANEEALRAMEQLEQMAPPPAEEKPAFDFQAKKA
                     AAKPKLDKAEITPMIEVTTEENRLVFEGVVFDVEQKVTRTGRVLINFKMTDYTSSFSM
                     QKWVKNEEEAQKFDLIKKNSWLRVRGNVEMNNFTRDLTMNVQDLQEVVHYERKDLMPE
                     GERRVEFHAHTNMSTMDALPEVEEIVATAAKWGHKAVAITDHGNVQSFPHGYKAAKKA
                     GIQLIYGMEANIVEDRVPIVYNEVEMDLSEATYVVFDVETTGLSAIYNDLIQVAASKM
                     YKGNVIAEFDEFINPGHPLSAFTTELTGITDDHVKNAKPLEQVLQEFQEFCKDTVLVA
                     HNATFDVGFMNANYERHDLPKISQPVIDTLEFARNLYPEYKRHGLGPLTKRFGVALEH
                     HHMANYDAEATGRLLFIFIKEVAEKHGVTDLARLNIDLISPDSYKKARIKHATIYVKN
                     QVGLKNIFKLVSLSNTKYFEGVPRIPRTVLDAHREGLILGSACSEGEVFDVVVSQGVD
                     AAVEVAKYYDFIEVMPPAIYAPLIAKEQVKDMEELQTIIKSLIEVGDRLGKPVLATGN
                     VHYIEPEEEIYREIIVRSLGQGAMINRTIGHGEHAQPAPLPKAHFRTTNEMLDEFAFL
                     GEELARKLVIENTNALAEIFESVEVVKGDLYTPFIDKAEETVAELTYKKAFEIYGNPL
                     PDIVDLRIEKELTSILGNGFAVIYLASQMLVQRSNERGYLVGSRGSVGSSFVATMIGI
                     TEVNPLSPHYVCGQCQYSEFITDGSYGSGFDMPHKDCPNCGHKLSKNGQDIPFETFLG
                     FDGDKVPDIDLNFSGEDQPSAHLDVRDIFGEEYAFRAGTVGTVAAKTAYGFVKGYERD
                     YGKFYRDAEVERLAQGAAGVKRTTGQHPGGIVVIPNYMDVYDFTPVQYPADDVTAEWQ
                     TTHFNFHDIDENVLKLDVLGHDDPTMIRKLQDLSGIDPNKIPMDDEGVMALFSGTDVL
                     GVTPEQIGTPTGMLGIPEFGTNFVRGMVDETHPTTFAELLQLSGLSHGTDVWLGNAQD
                     LIKQGIADLSTVIGCRDDIMVYLMHAGLEPKMAFTIMERVRKGLWLKISEEERNGYIE
                     AMKANKVPEWYIESCGKIKYMFPKAHAAAYVMMALRVAYFKVHHPIYYYCAYFSIRAK
                     AFDIKTMGAGLEVIKRRMEEISEKRKNNEASNVEIDLYTTLEIVNEMWERGFKFGKLD
                     LYCSQATEFLIDGDTLIPPFVAMDGLGENVAKQLVRAREEGEFLSKTELRKRGGLSST
                     LVEKMDEMGILGNMPEDNQLSLFDELF"
     gene            complement(24790..26871)
                     /gene="fusA"
                     /locus_tag="VU534_000915"
     CDS             complement(24790..26871)
                     /gene="fusA"
                     /locus_tag="VU534_000915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HEU1513525.1"
                     /translation="MAREFSLEKTRNIGIMAHVDAGKTTTTERILYYTGKIHKIGETH
                     EGASQMDWMEQEQERGITITSAATTAQWNNHRVNIIDTPGHVDFTIEVQRSLRVLDGA
                     VTVLDSQSGVEPQTETVWRQATEYGVPRIVFANKMDKIGADFLYSVSTLHDRLQANAH
                     PIQLPIGSEDDFRGIIDLIKMKAEIYTNDLGTDILEEDIPAEYLDQAQEYREKLIEAV
                     AETDEELMMKYLEGEEITNEELKAGIRKATINVEFFPVLCGSAFKNKGVQLMLDAVID
                     YLPSPLDIPAIKGINPDTDAEEIRPASDEEPFAALAFKIMTDPFVGRLTFFRVYSGVL
                     QSGSYVLNTSKGKRERIGRILQMHANSRQEIDTVYSGDIAAAVGLKDTTTGDSLTDEK
                     AKIILESINVPEPVIQLMVEPKSKADQDKMGIALQKLAEEDPTFRVETNVETGETVIS
                     GMGELHLDVLVDRMRREFKVEANVGAPQVSYRETFRASTQARGFFKRQSGGKGQFGDV
                     WIEFTPNEEGKGFEFENAIVGGVVPREFIPAVEKGLVESMANGVLAGYPMVDVKAKLY
                     DGSYHDVDSSETAFKIAASLSLKEAAKSAQPAILEPMMLVTITVPEENLGDVMGHVTA
                     RRGRVDGMEAHGNSQIVRAYVPLAEMFGYATVLRSASQGRGTFMMVFDHYEDVPKSVQ
                     EEIIKKNKGED"
     gene            complement(27296..27766)
                     /gene="rpsG"
                     /locus_tag="VU534_000916"
     CDS             complement(27296..27766)
                     /gene="rpsG"
                     /locus_tag="VU534_000916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HEU1513526.1"
                     /translation="MSRKNRAPKRDVLPDPLYNSQLVTRLINRVMLDGKRGTAASIVY
                     GAFEQIKEATGNDALEVFETAMENIMPVLEVRARRVGGSNYQVPVEVRPERRTTLGLR
                     WLVTIARLRGEHTMQDRLAKEILDAANNTGAAVKKREDTHRMAEANRAFAHFRW"
     gene            complement(27786..28199)
                     /gene="rpsL"
                     /locus_tag="VU534_000917"
     CDS             complement(27786..28199)
                     /gene="rpsL"
                     /locus_tag="VU534_000917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HEU1513527.1"
                     /translation="MPTINQLVRKPRKSKVEKSKSPALNVGYNSHKKVQTNVSSPQKR
                     GVATRVGTMTPKKPNSALRKFARVRLSNLIEVTAYIPGIGHNLQEHSVVLLRGGRVKD
                     LPGVRYHIVRGALDTAGVNDRKQGRSKYGTKRPKA"
     gene            28616..32458
                     /gene="spuA"
                     /locus_tag="VU534_000918"
     CDS             28616..32458
                     /gene="spuA"
                     /locus_tag="VU534_000918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored pullulanase SpuA"
                     /protein_id="HEU1513528.1"
                     /translation="MRKTPSHTEKKMVYSIRSLKNGTGSVLIGASLVLLAMATPTISS
                     DESTPTTNEPNNRNTTTLAQPLTDTAAGSGKNESDISSPGNANASLEKTEEKPAASPA
                     DPAPQTGQDRSSEPTTSTSPVTTETKAEEPIEDNYFRIHVKKLPEENKDAQGLWTWDD
                     VEKPSENWPNGALSFKDAKKDDYGYYLDVKLKGEQAKKISFLINNTAGKNLTGDKSVE
                     KLVPKMNEAWLDQDYKVFSYEPQPAGTVRVNYYRTDGNYDKKSLWYWGDVKNPSSAQW
                     PDGTDFTATGKYGRYIDIPLNEAAREFGFLLLDESKQGDDVKIRKENYKFTDLKNHSQ
                     IFLKDDDESIYTNPYYVHDIRMTGAQHVGTSSIESSFSTLVGAKKEDILKHSNITNHL
                     GNKVTITDVAIDEAGKKVTYSGDFSDTKHPYTVSYNSDQFTTKTSWRLKDETYSYDGK
                     LGADLKEEGKQVDLTLWSPSADKVSVVVYDKNDPDKVVGTVALEKGERGTWKQTLDST
                     NKLGITDFTGYYYQYQIERQGKTVLALDPYAKSLAAWNSDDSKIDDAHKVAKAAFVDP
                     AKLGPQDLTYGKIHNFKTREDAVIYEAHVRDFTSDPAIAKDLTKPFGTFEAFIEKLDY
                     LKDLGVTHIQLLPVLSYYFVNELKNHERLSDYASSNSNYNWGYDPQNYFSLTGMYSSD
                     PKNPEKRIAEFKNLINEIHKRGMGAILDVVYNHTAKVDLFEDLEPNYYHFMDADGTPR
                     TSFGGGRLGTTHHMTKRLLIDSIKYLVDTYKVDGFRFDMMGDHDAASIEEAYKAARAL
                     NPNLIMLGEGWRTYAGDENMPTKAADQDWMKHTDTVAVFSDDIRNNLKSGYPNEGQPA
                     FITGGKRDVNTIFKNLIAQPTNFEADSPGDVIQYIAAHDNLTLFDIIAQSIKKDPSKA
                     ENYAEIHRRLRLGNLMVLTAQGTPFIHSGQEYGRTKQFRDPAYKTPVAEDKVPNKSHL
                     LRDKDGNPFDYPYFIHDSYDSSDAVNKFDWTKATDGKAYPENVKSRDYMKGLIALRQS
                     TDAFRLKSLQDIKDRVHLITVPGQNGVEKEDVVIGYQITAPNGDIYAVFVNADEKARE
                     FNLGTAFAHLRNAEVLADENQAGPVGIANPKGLEWTEKGLKLNALTATVLRVSQNGTS
                     HESTAEEKPDSTPSKPEHQNEASHPAHQDPAPEARPDSTKPDAKVADAENKPSQATAD
                     SQAEQPAQEAQASSVKEAVRNESVENSSKENIPATPDKQAELPNTGIKNENKLLFAGI
                     SLLALLGLGFLLKNKKEN"
     gene            complement(32558..33607)
                     /locus_tag="VU534_000919"
     CDS             complement(32558..33607)
                     /locus_tag="VU534_000919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LLM class flavin-dependent oxidoreductase"
                     /protein_id="HEU1513529.1"
                     /translation="MVELGISTFGEITELEGTGQTYSHAERIRQLVAEIELADKVGLD
                     VYGIGEHHRADFAVSAPEIVLAAGAVNTKKIRLTSAVSILSSMDPIRLFQQYATIDAL
                     SNGRSEIMAGRGSFTESFPLFGYDLKDYDSLFDEKLDLLQLVNEKTKLDWQGRLTQTI
                     AGKEVYPRPVQDKLPLWIATGGHVESTVKIAQAGLPIVYAIIGGNPRYFKKLIQAYRE
                     IGSEAGHADKDLKVGAHSWGWIAEDGEQAVKDYFHPTKQVVDAISKDRPHWQELRYEQ
                     YLEQVGPNGAMFVGNPDQVAEKLIRMIEDLGLDRFMLHLPLGSMPHDQVLRAIELFGT
                     QVAPKVRAYFAMKEA"
     gene            complement(33726..35534)
                     /gene="glmS"
                     /locus_tag="VU534_000920"
     CDS             complement(33726..35534)
                     /gene="glmS"
                     /locus_tag="VU534_000920"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014621492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HEU1513530.1"
                     /translation="MCGIVGVVGNTNATDILIQGLEKLEYRGYDSAGIFVLDGADNHL
                     VKAVGRIAELSAKTAGVEGTTGIGHTRWATHGKPTEDNAHPHRSETERFVLVHNGVIE
                     NYLEIKEEYLAGHHFKGQTDTEIAVHLIGKFAEEEGLSVLEAFKKALHIIRGSYAFAL
                     VDSQDPEVIYVAKNKSPLLIGLGEGYNMVCSDAMAMIRETNQYMEIHDQELVIVKADS
                     VEVQDYDGNRRERASYTAELDLSDIGKGTYPYYMLKEIDEQPTVMRKLIQAYTDEAGQ
                     VVVDPDIIKAVQDADRIYILAAGTSYHAGFASKKMLEELTDTPVELGISSEWGYGMPL
                     LSKKPLFIFISQSGETADSRQVLVKANEMGIPSLTVTNVPGSTLSREANYTMLLHAGP
                     EIAVASTKAYTAQIAALAFLAKAVGEANGNAKAQAFDLVHELSIVAQSIESTLSEKET
                     IEVKVRELLETTRNAFYIGRGQDYYVAMEASLKLKEISYIQCEGFAAGELKHGTIALI
                     EEGTPVLALLSDPVLANHTRGNIQEVAARGAKVLTIAEENVAKDTDDIVLTTVHPYLS
                     PISMVVPTQLVAYFATLHRGLDVDKPRNLAKSVTVE"
     gene            complement(35727..37106)
                     /gene="bglA"
                     /locus_tag="VU534_000921"
     CDS             complement(35727..37106)
                     /gene="bglA"
                     /locus_tag="VU534_000921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000943526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HEU1513531.1"
                     /translation="MLRFPKDFVWGSSTSGPQTEGRVAGDGKGDNLWDYWFQVEPNRY
                     YNGIGSDKTSTFYENWERDIELLLETGHTAFRTSIQWSRIFPQGCGKVNTQGVDFYRK
                     VFEAIKAKGIRLLVNLYHFDLPFALQEDGDGWENKATVSAYEDYARFCFETYGDLVDQ
                     WITFNEPIVPVEFGYFYDAHYPHKVDAEAAVKVAYHTQLASSRAVKACHELLPDSKIG
                     IVLNLTPAYPRSQHPADVKAARIAALFQAQSFLDPSVLGTYPQELVEILHEHGLLPDA
                     TEEELELIRDNTVDFLGVNYYQPLRVMAPRFAKHPESPLLPEHFYEPYVMPGRKINSH
                     RGWEIYEQGIYDIAQNIKENYGNIEWMLTENGMGVEGEEKFRQDGMIQDDYRIDFVKG
                     HLRELHRAIEDGANCKGYLIWTFIDCWSWLNSYKNRYGLVELDLETQERRLKKSGHWF
                     KELSDNNGF"
     gene            complement(37205..39058)
                     /locus_tag="VU534_000922"
     CDS             complement(37205..39058)
                     /locus_tag="VU534_000922"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HEU1513532.1"
                     /translation="MKQSKMPIPTLREMPSDAQVISHALMLRAGYVRQVSAGVYSYLP
                     LANRVIEKAKNIMRQEFEKIGAVEMLAPALLSAELWRESGRYETYGEDLYKLKNREKS
                     DFILGPTHEETFTAIVRDSVKSYKQLPLNLYQIQPKYRDEKRPRNGLLRTREFIMKDA
                     YSFHANYDSLDSVYDEYKAAYERIFTRSGLDFKAIIGDGGAMGGKDSQEFMAITSART
                     DLDRWVVLDKSVASFDEIPAEVQEEIKAELLKWIVSGEDTIAYSSESSYAANLEMATN
                     EYKPSNRVVAEEEVTRVATPDVKSIDEVAAFLNVPEEQTIKTLFYIADGELVAALLVG
                     NDQLNEVKLKNHLGADFFDVASEEEVANVVQAGFGSLGPVGLPENIKIIADRKVQDVR
                     NAVVGANEDDYHLTGVNPGRDFTAEYVDIREVREGEISPDGQGVLNFARGIEIGHIFK
                     LGTRYSASMGADVLDENGRAVPIIMGCYGIGVSRLLSAVMEQHARLFVNKTPKGEYRY
                     AWGINFPKELAPFDVHLITVNVKDEEAQALTEKLEASLMGAGYEVLTDDRNERVGVKF
                     SDSDLIGLPIRITVGKKAADGIVEVKIKATGDTIEVHADNVLETLEILSKK"
     gene            complement(39071..40330)
                     /gene="rseP"
                     /locus_tag="VU534_000923"
     CDS             complement(39071..40330)
                     /gene="rseP"
                     /locus_tag="VU534_000923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000900658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HEU1513533.1"
                     /translation="MLGILTFILVFGIIVVVHEFGHFYFAKKSGILVREFAIGMGPKI
                     FAHIGKDGTAYTIRILPLGGYVRMAGWGDDTTEIKTGTPVSLTLADDGKVKRINLSGK
                     KLDQTALPMQVTQFDFEDKLFIKGLVLEEEKTFAVDHDATVVEADGTEVRIAPLDVQY
                     QNATIWGKLITNFAGPMNNFILGVVVFWVLIFMQGGVRDVDTNQFHIMPQGALAKVGV
                     PEMAQITKIGSHEVSNWESLIQAVETETKDKTAPTLDVTISEKGSDKQVTVTPKDSQG
                     RYLLGVQPGVKSDFLSMFVGGFTTAADSALRILSALKNLIFQPDLNKLGGPVAIFKAS
                     SDAAKNGIENILYFLAMISINIGIFNLIPIPALDGGKIVLNILEAIRRKPLKQEIETY
                     VTLAGVVIMVVLMIAVTWNDIMRLFFR"
     gene            complement(40352..41155)
                     /locus_tag="VU534_000924"
     CDS             complement(40352..41155)
                     /locus_tag="VU534_000924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HEU1513534.1"
                     /translation="MTQDLQKRTLFAGIALAIFLPILMIGGLLLQIAIGIIAMLAMHE
                     LLKMRGLETMTMEGLLTLFATFALTIPLENYLTFLPVDGNVVAYSVLISIMLGTTVFS
                     KSYTIEDAVFPLAMSFYVGFGFNALLDARVAGLDKALLALCIVWATDSGAYLVGMNYG
                     KRKLAPRVSPNKTLEGALGGILGAILVTIILMIVDSTVALPYGIYKMSVFAIFFSIAG
                     QFGDLLESSIKRHFGVKDSGKFIPGHGGVLDRFDSMLLVFPIMHLFGLF"
     gene            complement(41164..41922)
                     /locus_tag="VU534_000925"
     CDS             complement(41164..41922)
                     /locus_tag="VU534_000925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HEU1513535.1"
                     /translation="MFGFFKKDKAVEVEVPTQVPAHIGIIMDGNGRWAKKRMQPRVFG
                     HKAGMEALQTVTKAANKLGVKVITVYAFSTENWTRPDQEVKFIMNLPVEFYDNYVPEL
                     HANNVKIQMIGETDRLPKQTFEALTKAEELTKNNTGLILNFALNYGGRAEITQALKLI
                     SQDVLDAKINPGDITEELIGNYLFTQHLPKDLRDPDLIIRTSGELRLSNFLPWQGAYS
                     ELYFTDTLWPDFDEAALQEAILAYNRRHRRFGGV"
     gene            complement(42153..42725)
                     /locus_tag="VU534_000926"
     CDS             complement(42153..42725)
                     /locus_tag="VU534_000926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001098890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase family protein"
                     /protein_id="HEU1513536.1"
                     /translation="MNTVKNKQEILEAFRESPDMMAILTIIRDLGLKDSWLAAGSVRN
                     FIWNLLSDKSPFDHETDIDVIFFDPDFSYEETLLLEKKLREDFPQYQWELKNQVYMHQ
                     HSPHTASYTSSRDAMSKYPERCTAVGLRLNEELDFELYVPYGLEDILNFQVRPTPHFL
                     ENEDRMELYQTRLSKKNWQEKWKNLIFKNT"
     gene            complement(42706..43677)
                     /gene="ruvB"
                     /locus_tag="VU534_000927"
     CDS             complement(42706..43677)
                     /gene="ruvB"
                     /locus_tag="VU534_000927"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000502070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HEU1513537.1"
                     /translation="MGDEELVERTLRPQYLREYIGQDKVKDQLQIFIEAAKMRDEALD
                     HVLLFGPPGLGKTTMAFVIANELGVNLKQTSGPVIEKAGDLVAILNDLEPGDVLFIDE
                     IHRLPMSVEEVLYSAMEDFYIDIMIGAGEGSRSVHLELPPFTLIGATTRAGMLSNPLR
                     ARFGITGHMEYYAHADLTEIVERTADIFEMEITHEAASELALRSRGTPRIANRLLKRV
                     RDFAQIMGNGVIDDVITDKALTMLDVDHEGLDYVDQKILRTMIEMYSGGPVGLGTLSV
                     NIAEERETVEDMYEPYLIQKGFIMRTRSGRVATAKAYEHLGYEYSEK"
     gene            43839..43931
                     /locus_tag="VU534_000928"
     CDS             43839..43931
                     /locus_tag="VU534_000928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HEU1513538.1"
                     /translation="MMELVLKTIIGPIVVGVVLRIVDKWLNKDK"
BASE COUNT        13144 a        10189 c         8525 g        12757 t
ORIGIN      
        1 aagattatac cacattgtgt actatttttg gttcatttta ctatatttct aaacacttag
       61 aaataataaa acaaattaaa tattatttct aaatatttga aaataacatc tatttgtatt
      121 atactatctt tgaggtaact attatgaact atatcaaaag accacattat ttagattttt
      181 taagaaaaca tcgtgaccga ccaatcatca aagttgtgag tggagttaga cgagctggta
      241 aatctgtgct ttttcaactc tataaagagg agttactagc aactggggta gacgaggatc
      301 agattatatt catcaatttc gaagatttga gttactatga tctgcgacat tttcaaacat
      361 tattcgctta tataaaagat caattagtta gcaagaaaac atactatatc tttttagatg
      421 aaattcaata tgttgaaaaa tttgaactgg tagcagatag tctattcatc ttagcaaatg
      481 tagacctcta tttgactgga tctaacgcct actttatgag tagccaatta gcaacaaact
      541 tgactggtcg gtatgttgag atagaggttc ttcctttgtc atttgaagaa tatctatcag
      601 gtcaatctct cacagagaat ctgaatacaa cagaaatttt taacaattat ctctttagtg
      661 ctttccctta cttattgcaa acatcatctt acgatgaaaa aattgactat ctcagaggaa
      721 tatataactc catactgtta aatgatattg tcactagatt gggaaaacca aatcctacta
      781 ttattgagcg cattgtccga acccttctca gtagtacagg tagcttaata tcaacaaata
      841 agattcgcaa taccctagtc agccaaaatg tttcaatatc ccataatact ttggaaaatt
      901 atttgacaac tttgacagat agtttacttt tttattccgt tccacgtttt gatgtaaaag
      961 gtagagcatt attgcaacgt ttagaaaaat attatcccgt tgatttaggt ttacgacatc
     1021 tcttattacc agaccagaaa gaagacatta ggcatatctt ggaaaatatg gtatatttgg
     1081 aattgagacg tagatattca caagtatatg ttggtaattt agataagtat gaggttgatt
     1141 ttgttgttgt aactgatctt ggccactacg cttattatca ggtcagtgaa acaacacttg
     1201 ctccagaaac actagaaaga gaacttagac cactagaagc cattaaagat caattcccta
     1261 aatatctatt aacaatggat acgattcagc caacagccaa ttacaatgga atcgagaaga
     1321 aaagcattat agattggtta ctagaaaaat agataaatat aaatcataca gctaattaga
     1381 tttgcaacag tctgttatca atgattctac ccaaatccta acaagatata gtgaatttcg
     1441 aatacgctat ataatacgga cacttgaaaa tagaaattgg ggatgaaagg ggatctataa
     1501 tttctggaag tactatcaaa aattaatatc atagtcttat tagagaatag catcacccac
     1561 tttctcaaat aagattaaat tgtaactgaa ttataatgaa aaagagactg agcaatcagt
     1621 ctttaaaatc agaaaagcgc atagtatcag gtattgaaca accttgataa tatgcgtttt
     1681 attatggaaa tatttgcttc attttctcct gaaatagagc ttttgctatc ctatttttct
     1741 ctatttctaa tgatttactt caacttctta cctcttggga aaaacaacaa agatatgaac
     1801 tagcaaagtt tggcatcctc agtaatccag aacaatttgt ttttacatat atcgacacaa
     1861 aaggaaacat caacaagcct ttacatgccg actatctgaa caataaaatg aaaagcatta
     1921 gaaagcgaca taaagaactg acacacgcta caccgcataa attacgacat acaggagcga
     1981 cacttgctaa aaaagcagga atgagcttag aagccatttc tgaagcatta actcatagcg
     2041 ataccgttac aactaagact tatgttaata cttcaaacat agttccatta tctgctggac
     2101 aagttgccta ccaacatctt aaaaataagt agggtaattt tagggcaaat tttagggtaa
     2161 acttttttag aaagtataga aaaaagcacc catagggtaa acccttgagt gctttgaaac
     2221 gttgatataa tcgtattgat taacgttttg aggcaactga ccatgtcagg ttgcagccac
     2281 atttgtaagc gactaaagtc gcaacaactg tgtcaattgc accaatttag taagaaagta
     2341 taaaaaaaga acaccccgaa aggtgctctg tataagtata gtaattcttt cgaattaacg
     2401 tttactaaat tgtgatgctt tacgagcttt cttaagacct ggtttcttac gttcaacttt
     2461 acgtgagtca cgtgtaagaa gtcctgcgcg tttcaatgaa tcgcggaagt ctgggtctac
     2521 ttgaagaagg gcacgagcga taccgtgacg gatagctcct gattgaccag cgtatccacc
     2581 acctataacg ttaacgaaaa cgtcgtatga acctacagtt gaagtaactg cgaatggttg
     2641 gttgatgaca agacgaaggt cagcgtgtgg gatgtactct tcaacatctt ttttgttaac
     2701 agtgatttta ccagttcctg gaacaaggcg aacgcgtgca acagcgtttt tacgacgtcc
     2761 agtacctgca tattgtgctt gtgacatact ttattgttcc tttccttaga taagtcctga
     2821 aatgtcaaga acttctggtt gttgtgcagc gtgagtgtgc tcagctccaa caaatacttt
     2881 caacttcata ccttgagcgc gtccaagtgt attgtgtgga agcatacctt taactgattt
     2941 ctcaatcaaa cgtactgcat ttttagaacg aagttcacct gcagagattt gtttcaatcc
     3001 acctgggtgg tttgagtgag tgtagtagat tttatcagtt gcttttttac cagtcaattt
     3061 aactttttca gcattgataa caatcacgaa gtcacctgta tcagtgtgtg gtgtaaatgt
     3121 tggtttgttt tttccgcgaa gtacgctagc aactactgca gaaagacgtc caagtggtac
     3181 atcagttgcg tcaactacgt accatttacg ttcaacttgg cctggtttag ccataaatgt
     3241 tgttttgttc atgatttctc ctatatatag ttcgattttt gtttacggtg atgggtgttc
     3301 cttcccatcg aaaagtattt ggaaggttcc ggggcctttc aaatggggta aacaataccg
     3361 cctactatca taccaaattt tacccctaaa agtcaataga tatgaaaaat atttttcggt
     3421 aacttctcaa agtaactgaa agttatataa tcaagttaat ttgggaattt acctattaac
     3481 ttcggtagat ttttaggaat tttttcccta tttctccctg taactaaaat ccttttcaaa
     3541 aaatcacctt ttcttgattt ttaatcctat ttgctgtatg ataagggaaa agaaagggga
     3601 cagagatatg gcttttacca atacccacat gcgatctgct agttttggta ttgttaccag
     3661 cttgcctgat gacatcattg actctttttg gtatatcatc gaccatttct taaaaaatgt
     3721 ctttgaattg gaagaagaac tcgagtttca attgcttaat aaccaaggaa agattacctt
     3781 ccacttttca agtcaacacc tccctacagc cattgatttt gactttaacc atcctttcga
     3841 ccctcgttat cccccaagag tactggtttt agacatggac ggtagagaaa ctatcctcct
     3901 cccagaagaa aatgacctat tttaatactc aatgaaaatc aaagagcaaa ctaggaagct
     3961 agccgcaagc tgtacttgag tacggtaagg cgacgctgac gtggtttgaa gagattttcg
     4021 aagagtataa aaactctagc cttcagttgc aagtaactga aaactagagt ttttctattt
     4081 tttcaaagca tcatacaagt tgcggatcgg ttgttttaat atcggatgga taaaatgagg
     4141 cgcaatttcc tgtaaggact caaggacaaa aaggcgttcc gctatgtaag gatgaggcaa
     4201 tatgaggtcg tctgtataaa ggatctggtc ctccacaaag agcaagtcca aatcaatcaa
     4261 acgaggtccc caatgcactt ctctcacccg tcccagctct gactcaatgg ctaacaaggt
     4321 ttctaacaag tcttgtgctg gtagccaggt ttccacctca accacttgat tggcaaagct
     4381 atcctgctcc actccacccc aaggctccgt cgctaagaca ctggactctt tgagaatatg
     4441 gatgccacga gctcgcagtt tgtcaatggc ttgcttcaag tttgcttgtt tatctcccat
     4501 attgcttcct agggcgataa aggctcgttg cttgcggcga tgaatggtta ccgagcaagt
     4561 atctagtgac aaatgcaccg gtgcccaagg ttttttcagt tccaacttca tttcttggac
     4621 aagaggataa aactcaaagg tacgttccac cagtttatag gctaccgttt caatcaaatc
     4681 ttcactcgtt tcctgaaacc aagtcgtcca ctgctgacac aattctccgt aatggacaga
     4741 ggctgttaaa tccaagtctg tagctgcctt ggtcatatca taggatagga tggctgaaac
     4801 gacaaatttc tgccccaatt ctttctcact aggaaaaaga ccatgatagg caaacatttc
     4861 caaatcctta atctgcagtt gatccataat gattcctttc tagaaaaatc cgcttgaagc
     4921 ggattctttt tatagcccca ttaaacgata agcttggtca cggagatcct tatctgtttc
     4981 aaatagacca cgagctactg tcgtcaaggt tgcagtgcct ggttttctaa caccacgcat
     5041 actcatacac atatgttccg cctcaatgac aacaaaggct cctttagcac ctagatagtc
     5101 catcaaggca tcggccactt cgatattcaa acgttcttga atttgtggtt ttttcgaata
     5161 aacttcaacc gtacgggcta gcttagacaa gcctgccaca cgaccatctg gaatgtaggc
     5221 aatgtgcgct ctaccataaa atggcaagaa gtggtgttca cacatggtat ggaaaaagat
     5281 atccttttct accaccatat tatcgtcaat aatttcaaag gattttgaca aatgttcctc
     5341 tgctgtttga ccaagacctg aaaaaatctc ttgatacata cgggctacac gagcaggtgt
     5401 ttcctgcaag ccctcgcgat tagcgtcctc tcctacagcc tcgataatca tttttacagc
     5461 cgcttcaatc ttttgtgtat ccattctcgt tcttcctctc catcagatag gccctcactt
     5521 ggctcaagaa atacaaggaa cctgtgacaa tcctaactgt ttgtttctct tcttttttat
     5581 ctgtcaaatt ctgctctaga aaatcatgcc aatcttggta gctgagattt ctagacttag
     5641 ctgcctcttt cagcacgttt tcatccgtcg cccgactatc cgcaaaatgt gttagagtaa
     5701 gctcggtaac tggcatggct cccagcaagt ccaacatatc ctccaaggcc ttggttttga
     5761 tacaagtgaa gaggatttcc ttatgataat ccgcaaaacg ttcttgcaag gttaccaaca
     5821 aggccttgat agcatgggga ttgtgggctc catccaaaat catcaaggga tctcttgaca
     5881 cgatttccaa acgccctggc caacttgttt cttccaaggc ttgaccaaga aaatcattgc
     5941 ttgctagctc tcgaccatct tcttgacaaa aagtatcaag taaagctatg gccatcccag
     6001 cattctctat ttggtacaaa ccaagcaggc tagtctggaa gcgaccttgt ctgacagcac
     6061 ttgtatagtc aaagacttcc cctgtcacca cactttcttg atgacgaacc tgataatctg
     6121 tcccgtaggc aagtctcggc gcatctttcc cttccgcaat gcggtcaatc acagccaagg
     6181 cttctggagc aatacgccct gttaccaagg gcatcccttg tttgataata cctgccttct
     6241 gctctgctat gacctccaag gtgtcaccaa gtagagccac atgatccaag ccaatagttg
     6301 taattcctgt caaaatgggc tgacagacat tggtactatc caaaagtcca cccatgccaa
     6361 cttccatgat ggccacatct acttgctctg aggcaaagta gtcataggcc agggctgtga
     6421 taatctcaaa ctcggttgtg ccctgtaaat tggcgaccgc ttctccctcc agcaaagact
     6481 gatagtctgc catgagagct tctagcctcg cttctgagat cgattcccca ttgatgctaa
     6541 tctggtctgt gtaatgaatg agatagggcg agctaaacac gccaactctc aaccctagct
     6601 tttctagcat ctttttcaaa aaagcaatag tcgagccctt gccgttagtc cctccgatat
     6661 ggaggacctt gagtttgaga tggggattgc cacgcaaagc taacagttcc accattcgtt
     6721 ccaagccaaa atgcggttga tccgtccggt agttagcaat ccactgattg ttttcaattt
     6781 ctttcatctt atttatattg ttttaaatct aaattttccg cttcatcagc cagacgaatg
     6841 gcagaggcaa tttcaactgc catcctgtga ctagctacgt catgcacgcg caccacttct
     6901 acaccctgtc tcgcagcgat actagttaca tgagccgaag ccgtgtcccg atttcggaaa
     6961 ccaagctctg tctcaggatt gacttcaaaa ccattctcct ctaggatatt gatgacaaat
     7021 cgcttgcgcg acactccgag aaagattgga tagcccttct gatgtagttt atccaggtcc
     7081 cgtaaaagaa gcagattttc tttcttggtc agaccaaagc caattcctgg atccaacagg
     7141 atattttctg gtgcaatacc agcttctgcc gctctcgcta gtgctcgttc aaagaaagcc
     7201 accatcaagt cttcgattgg caatgtttca aagtcagcta actctttttc tgtaaaggtt
     7261 tgaccaaaac caaaatgagg gaagataagc gaactaggat gctgaggtcg agccataact
     7321 gggttaaaca tgatgaccac tttcgctctc gcttcagcta ccacataagc cattttctca
     7381 tcacccataa gaccagtgat atcattgact agatcggcac cagcagccaa agcagcctct
     7441 gctacttgac tcttccaagt atcaatagag atgaggacat cactttcctt gcgaatcgct
     7501 ttgatcactg gaacaacacg ctggatttcc tcttctatct caacatagct acttcccggc
     7561 cgagtcgatt ctccgccgat atctagcata ctggctcctt ctgctatcaa tttacgagcc
     7621 tgctggagcg cctgctcaag agcaaaaaat tgaccaccgt ccgaaaagga gtctggggtt
     7681 acattgataa ttccgcaaat aactgtcttt gcatgattgg ctttacttga catatcggtc
     7741 actccctcaa ggattttcat catattattt ttctatttta ccataaaaag aaaaagatgg
     7801 acacgattgc attcatcttt ccctggtaga aagaggtcgg ttcctacata aaaactttta
     7861 aacagaaatt cctaatgtcc gactcataat caccacaaga gccaacaaac agaaagcaat
     7921 cccattaaca atcatgtgaa gcaagatcga catttccaaa cgttgggtct tgtaggctgt
     7981 ccaagataga actgtcgaca tacctccata aatcaataaa gaaggtaaat tacttggttg
     8041 atgcaataaa gcaaacacaa tcgtaccgac tacaaatccc aagttctcct tgcctcggaa
     8101 aatcttttta ggaacaatcc cacgacacaa gatttcctca caaatcggag caagcaaggc
     8161 tagcaagaag aaactggaaa tcaacgaact attttgaacc atatcattaa tctgagactg
     8221 gttagctgtt gtcgtctcat ttgacagttg caataaaatg gaaccaagta tatttgaccc
     8281 gacaataact agataactca agcccaaacg tgccaaatct ttagctctaa aaaaagaaaa
     8341 attaaaacta gctaacttgg ttttacgagc tcccataata aatagagcca gaaccacaat
     8401 tgaaaggcca gcaactatca gccctgactg tagcagggct acttctttta aagtcaaaat
     8461 agaggtaacc actaggggaa cctgatataa aaggacggca agtaaaaaga ccaaaatcca
     8521 gcctgcacga ttcaacaatt ctttccacat atttttctct ttcatcacct atctcctttg
     8581 tattaaaaaa ggggggaaat ccccctgggt cattctatta taaggccatg ctgatgtagt
     8641 taaggataaa caaggcatcc aaaatccaaa tcatgacatg aacatcttta acttgacctt
     8701 taacaagctt agtcaaagtg taagtcaaga aaccaactgc aatcccttga gtgatagagt
     8761 agctgaatcc cataaagata gatgtgaaga aggcaggaac tgcttcagac atatcatccc
     8821 aatggatatt tttcaagcta ccaagcatca taatcccaac gataatcaag attggagctg
     8881 tagccgctgt tggtacgatc gctagaagtg ggctaaagaa gcttgaaatc gcaaaacaga
     8941 tagctacaac caaggctgtc aaaccagtac gtccacctgc accgatacca gcagcagact
     9001 caacataagt cgttacgttt gaagtacctg caatggcacc gactgtcgtt ccaatcaaat
     9061 cagagtaaag agccttatcc aatttggctg attggtgatt ttcaccattt gtcgctacga
     9121 taccaacttt ttcacctgta ccgatcaagg taccaattgt gtcaaaaata tctgtcaatg
     9181 agaaggcaag aatggccatc agagtttcag gcaagcgagc tgtatctgaa accaaagctc
     9241 ccaatccttc tgaaccaaga gctgcaccaa agattgtctt caaatcttca aaagctgcac
     9301 caacatggtt attagcaaaa tcgatactag acaaatcaac caaaccaact gcaatagcaa
     9361 gaacagttgt tgtcaagata gagagaataa ttcccccttt aatccctttg atgacaaaga
     9421 agatagtaat ggcaagtcct gcaagagcca ctaaaacagc tggattatta aagctgacca
     9481 atcctggaac tgctgaagag tttgctgcaa tcgttgcttg agctttgtca gccccttctc
     9541 ctacaacagt atagttgcct ggatcaatcg tgaatttcaa aagtccagca ttcttaatcc
     9601 ctacataggc aaggaagaca ccgataccag ctgaaatagc tgagcgaaga gcattgggaa
     9661 tcgattcaat gatcatttta cgaacatttg tcaaggtaat aatcaatgaa ataatcccac
     9721 agatgaagac catagctagg gcttcttgcc aagaataacc aagcccgaat acaactgtaa
     9781 aggtaaagaa ggcattgagt cccatacctg gcgcttgggc ataaggtaag ttagcataaa
     9841 aagccatcat caaggtaccc gctactgcac caataatcgt cgctaggaag acgccctgag
     9901 caggcattcc tgtttgtgaa agtatttgtg ggtttacaaa gagaatatag ctcattgcaa
     9961 agaaagttgt taaaccagcg agaacctctg tacgaacgtc tgtaccgttc tcttttagtt
    10021 taaataattt gtccatcatc aatctccttt taatttttac gaacaataat agaattatat
    10081 catttatcat tcactttttc aatgtctttg tttgatttgt ttaagaaatt aatccaattt
    10141 cattttttgt ttggaatctg cttttctgcc tgctttctgt tataatagaa gacatcttat
    10201 ctgaaaacac actagaaagg tccatatgac gaaaaaaatt attgcagttg acctggatgg
    10261 aaccctgctc aactcagaca gtcaaatttc tgactttacc aaaagaacca tcaaaaaagt
    10321 tgctgaaaaa ggccatcagg ttattattac gacaggtcgc ccttaccgta tgtcaaaaga
    10381 tttttaccgt gaactgggct tagacactcc tatgattaac ttcaacggat cccttactca
    10441 tttaccagac caagtttggg attttgaaaa gtgtttgact gtagacaaaa aatatctgct
    10501 agatatggtt caacgttcag aggacattca agccgatttt atcgctggag aatatcgtaa
    10561 aaaattctac attacaaatc ccaatgaaga aattgccaat cccaaactat ttggtgtaga
    10621 agctttccag cctgaagatc aattccagcc tgaattggtg accaaggacc ctaactgtat
    10681 cctcttgcag actagagcca gtgacaaata ttccttggca aaagaaatga acgccttcta
    10741 ccagcatcaa ctttctatca atacctgggg aggtccgctc aatatccttg aatgtacccc
    10801 aaaaggtgtc aacaaggcct ttgctttgga ctacttgctc aagataatga atcgtgacaa
    10861 aaaagatttg attgcctttg gagatgaaca caatgatacc gaaatgctcg cttttgctgg
    10921 gaagggttat gccatgaaaa atgccaatcc agagctactc ccttatgcag atgagcaaat
    10981 ttcccttacc aacgaccaag atggggttgc caaaacccta caagacttat tcttataacc
    11041 tatactgata ctcaatgaga atcaaagagc aaacttagga agctagccgt aggttgctca
    11101 aagcactgct ttgaggttgt agatgaagct gacgtggttt gaagagattt tcgaagagta
    11161 tgaccagctt gcaagctggt ctttgtgctc ttttcacagt ctcatcaacc agttaatcga
    11221 ttgttctact ttttgtctcc aaaaccttgg aaaaggcttt cttttgtgat atacttcaca
    11281 tataaataca agagagctcg tcacactcga ctctgttgac aaaaaatcaa tccagtcccg
    11341 ttgtccctgt tctcggtcaa tatcaaggag gatagctatg aaagctgttg ttgtaaatcc
    11401 agaaagcact ggtgttgcta ttgaagaaaa agtactccgt ccacttgaaa ctggggaagc
    11461 acttgtagaa gttgaatact gtggcgtttg ccacaccgac ctccacgttg ctcatggtga
    11521 ctttggtcaa gtcccaggac gtgttcttgg gcacgaaggt atcggtatcg ttaaagagat
    11581 tgctccagat gtgaaaagcc ttaaagtcgg tgaccgcgtc agcgttgctt ggttctttga
    11641 aggatgtggc acttgcgaat actgtacaac tggtcgcgaa accctttgcc gtacagtgaa
    11701 aaatgctggc tactcagtag acggtggtat ggctgaacaa tgtatcgtaa ctgctgacta
    11761 tgctgtcaaa gttcctgacg gacttgatcc agcccaagct tcttctatca catgtgctgg
    11821 agtaacaacc tataaagcta tcaaagaagc aaaagttgaa ccaggccaat gggttgttct
    11881 ttacggtgct ggtggacttg gtaacctcgc tgttcaatac gctaaaaaag tattcaatgc
    11941 tcatgttatc gcagtcgata tcaacaatga caaacttgcc cttgcaaaag aagtaggcgc
    12001 tgacattgtg attaacggcc tcgaagttga agatgtagct ggactcatta aagaaaaaac
    12061 tgatggagga gctcattcag ctgtcgtaac tgctgtgtct aaagttgcct tcaaccaggc
    12121 tgttgactcc attcgtgctg gtggtcgcgt cgtcgctgtt ggtcttcctt ctgaaatgat
    12181 ggaactcagc atcgttaaaa cagtcctcga tggaatccaa gtcatcggtt ctcttgtcgg
    12241 aactcgtaaa gacttagaag aagccttcca atttggtgca gaaggtctgg tagtcccagt
    12301 tgttcaaaaa cgtccagtag aagatgctgt tgccattttc gacgaaatgg aaaaaggcca
    12361 aatccaagga cgtatggtac tcgacttcac ccactaatct aatagaaacc tattttaaaa
    12421 gttggaagct tcttccaact tttttatatt aaattttaaa taagaattca agattactcc
    12481 tcaaaaactc aacatatcaa catacaaaaa taaaaatttt ttaatttttt atgataaata
    12541 gttgcttttt ttatgaaaac ggtttatact taaacagtct taaagttttc ttaaatgaaa
    12601 actaaaacaa aaaaggagga atgacaataa tgagtatcgg aatcattatt gcgagccacg
    12661 gcgaatttgc tgcgggtatt catcagtcag gatctatgat ctttggtgaa caagaaaagg
    12721 ttcaagttgt gacctttatg ccaaatgaag gtcctgatga tctatacgct aagtttaata
    12781 acgctgttgc tgcatttgac gcagaagatg aggttctagt tttggctgac ctttggagtg
    12841 gttctccatt taaccaagct agtcgcgtga tgggagaaaa tcctgagcgt aagtttgcca
    12901 tcatcacagg acttaactta ccgatgttga ttcaagccta cacagagcgc ctcatggacg
    12961 ctgctgcagg tgtagaaaaa gtcgctgcta atatcattaa agaagccaaa gatggcatca
    13021 aagctcttcc agaagagcta aatccagtcg aagaagttgc aagcgctgca gctgctccag
    13081 ttgcccaaac tgctatccca gaaggaactg ttatcggaga cggtaaattg aaaatcaatc
    13141 ttgcccgtct tgacacacgt ctacttcacg gtcaggttgc aactgcttgg actccagatt
    13201 caaaagcaaa tcgtatcatc gttgcttcag ataacgtggc taaagacgac cttcgtaaag
    13261 aattgattaa acaagcagct ccaggtaatg tcaaggctaa cgtggttcca attcaaaaac
    13321 tgattgagat ttcaaaagac ccacgttttg gagaaacaca tgcccttatc ttgtttgaaa
    13381 cacctcaaga tgcccttcgt gccatcgaag gcggcgtgcc aatcaagact cttaatgttg
    13441 gttctatggc tcactcaaca ggtaaaacat tggtcaatac cgttttgtct atggacaaag
    13501 aagacgttgc tacatttgaa aaaatgcgtg acttgggtgt tgaatttgat gtccgtaaag
    13561 taccaaatga ttctaaaaaa gatttgtttg acttgattaa caaagccaat gtcaaataag
    13621 ccattattta tgaaaggatt ttaaacatgt ctattatttc tatggtttta gtagtcgttg
    13681 tagccttctt tgcaggtctt gaaggcatcc tcgaccagtt ccaatttcac caaccacttg
    13741 tagcctgtac ccttattggg cttgtaacag gtcacttgga agcagggatt atcctcggtg
    13801 gatcgcttca aatgattgcc cttggttggt caaatatcgg tgctgctatc gctcctgatg
    13861 ctgcacttgc ttctgtcgct gctgccatta tcatggttct tggtggtgac tttaccaaga
    13921 ctggtatcgg tgttgcccaa gcggttgcta tccctcttgc tgtagctgga cttttcttga
    13981 caatgattgt tcgtacaatt tcagttggtt tggttcatac tgcagatgct gccgctaaaa
    14041 aaggtgactt cggcgctgtg gagcgtgcgc atttcatcgc gctacttttc caaggacttc
    14101 gtatcgcgct tcctgcagct cttctcctta tggtaccaac tgaaactgta caaagtatcc
    14161 ttagtgccat gccagactgg ctcaaagatg gtatggctat cggtggtggt atggtcgttg
    14221 ccgttggtta cgccatggtt atcaacatga tggcaactcg tgaagtatgg ccattcttcg
    14281 ctcttggttt cgttctcgct gctgtgtcag atattactct aatcggattc ggtgctatcg
    14341 gcgttgctat cgctcttatc taccttcacc tttctaaaac tggtggaaat ggtggcggag
    14401 gagccgcaac ttctaacgac ccaatcggcg atatcctaga agactactaa gataagaaag
    14461 gactgaaaac atcatgactg aaaaacttca attaactaaa tcagatcgta aaaaagtttg
    14521 gtggcgttca accttcttac aagggtcttg gaactttgaa cggatgcaaa acttgggctg
    14581 ggcttataca ctcattccag ctatcaaaaa actctatact aaaaaagaag atcaaatcgc
    14641 tgctcttgag cgtcaccttg agttcttcaa cactcatcca tacgtagctg ctccagtcat
    14701 gggggttact cttgcgcttg aagaagaacg tgctaacggt gtggaaatcg atgacgctgc
    14761 tatccaaggg gttaaaatcg gtatgatggg acctcttgct ggtatcggtg acccagtatt
    14821 ctggtttaca gtacgcccaa tccttggatc tctcggtgct tcacttgccc ttactggcaa
    14881 tatcttgggg ccactcctct tctttgttgc atggaacttg attcgtatgt cattcttgtg
    14941 gtatgttcaa gagattggat acaaggctgg atcagaaatc actaaagata tgtctggtgg
    15001 tatccttcaa gatatcacta aaggagcttc tatccttggg atgttcattc ttgctgtcct
    15061 tgttcaacgc tgggtaaata ttaaatttgc tttcgatgtt tctaaagttc aactagatga
    15121 aaaggcttat atccattggg ataaattgcc agaagggtct aaaggtatcc aagaagcatt
    15181 cgcacaagta ggacaaggat tgtctcaaac tcctgaaaaa gttactactt tccaacaaaa
    15241 cttggatatg ttgattcctg gattatcagg actactcctt actttacttt gcatgtactt
    15301 acttaagaaa aaagtatctc caatcactat tatccttgcc ctcttcgcag tgggtattgt
    15361 ggcacatgtt cttcacatca tgtaatcaag caactaaaaa ggaaccaggt tctaaaatct
    15421 gattcctttt ttctatgctt ttattcagcc aaggctccca ttggatccca tggtgcaagt
    15481 acgattggtt ctgctccata ggcagcttgt tcttctgctg tcagcaattc cttacgaaca
    15541 acgatttggt atgtgtattc gtccatccaa gcgtctgagg caacaaagta accatctgta
    15601 ccgaccttgt ctccccatga gttttcaacc ttccacttgg ttgatttacc attttcgtcc
    15661 aagtcaacac ctgtcaagac catggcgtgg gtcatcaagc tttcactata gtccaaacgt
    15721 ccagccttgt cttgagtaag tttaatgtcc atgcttgatt caaagtcata aacatctgtc
    15781 gcaaggatgc cagccttacg gttgctgagc tggccgacat cagaaccaaa ccaaacagtc
    15841 tcacctgctt gcatttgggc aatcgccaat tctttcaagc gctccattgg aacgttgatg
    15901 tagcgaactg cacggctacc aaccacattc cccaacatct caactgtgta agattttccg
    15961 taaggtttat cagcagttgg agcattgata acagaaacgt agtcttctaa aggaagattg
    16021 acatatttct tgtaaaactc ttgtggtgtg attccttttt cacttttgta gttgttatct
    16081 ttatcgcgat aagcaaagtc aaacttgcgt ggtggaagtc ctaatgacat agcaagaaag
    16141 ttaaagattt cttgcaagag gtcttctttc ttagcttgaa cagtcgcttg atctgcacca
    16201 gaaacaagca agtcacgcaa gatttgagca tcttgacgaa gcaatttatt aaggatcgca
    16261 tttagctcac gactgctgct agatgaaaca gactcaggat aaactgactt aggcacgaca
    16321 ccgtattttt caaagaggga aacgaccata tcccattgac cgccatcttg ttgaggtgtt
    16381 tggagtaaga agctaacctt gcggctagtc aattcttggt ctgaagtcgc aatgacttgc
    16441 tccaagaacc agtttgattt ctcatactta tcccagaaga aagtgtgggc ttgtgacaac
    16501 tcaaagttct ccaatttgta ttgcgagatg agtttgtggc ggaaggtgtt gagagccgca
    16561 aacatccagc aacgaccaga cgctttctgg ttagtgacct tgtccttggt taaatccaat
    16621 gagaaaacag gtgtgttgtc tacatggctt tggcgacgtt ccagagctgc aaaaattccg
    16681 ttgtggctgg cagcattttc aatcgcttgg tattttacat ttgcttcata gttggcaaat
    16741 agtttatcag taaatgattc ttgaatcgcg ttcatagatt cctcctttta ttctacagtc
    16801 tattataact cttttcacaa aggaagcaac taaaaaacat aaaaggcgag gacattgtcc
    16861 ctcacctttt tcgaatttat actcttcgaa aatcaaattc aaaccacgtc aacgtcgcct
    16921 tgccgtactc aagtacagcc tgcggctagt ttcctagttt gctctttgat tttcattgag
    16981 tattaaacta aattaaataa tattagcgcg gagaatttct aattcttcct tggtcaagcg
    17041 acgccattcc cctcgttcta ggttctcatc taatactaaa gttcccatag tcaatcgttg
    17101 caagtccacc acttccttgc cacagtagcc caccatacgc ttgatctgat gaaacttccc
    17161 ttctgcaatg gtcacacgga tttggctttg attcttttct gtatctatgg atacaagctc
    17221 cagtatagcg ggttgacagg taaagtcttt gagaggaata ccctcagcaa atgtctccac
    17281 atcttcttgg gtcatgattc ccttgacttg tgccagataa gtcttgtcca catgacgctt
    17341 gggcgaaaga agaacatgag ccagctgacc atcattggtc aagagcaaaa gaccatgcgt
    17401 gtcaatatcc aagcgtccta ctgggaaaac ttccttactc cgcgccaagt catccaacaa
    17461 gtccagaacg gttctgtgct tgggatcctc agtcgctgag ataactcctt tgggcttgtt
    17521 catcatgtag tagacaaact cttcatactc caacacttgc ccatcaaagc gaatctcatc
    17581 tattttttca tcaatctgca atttagctga tttttctttt ttaccattta cagtcacgcg
    17641 cccagccttg agcaagtttt tgacctcagt ccgacttccc accgcacagg caactaaaaa
    17701 tttatctaat ctcatagaac tattatatca tatcaaaagg aggctagtac aatgaccaac
    17761 ctccttttcg tttcatactc ttcaaaaatc tcttcaaacc gcgtcaacgt cgccttgccg
    17821 tatatatgtt actgacttcg tcagttctat ctgcaacctc aaaacagtgt tttgagctga
    17881 cttcgtcagt tctatctgca acctcaaagc agtgctttga gcatcctgcg gctagtttcc
    17941 tagtttgctc tttgattttc attgagtatc agatttagga aattaacttc ctcgtctcca
    18001 aaaaatagct aaaacaatca tggctcctaa aatcgctggg ataatagctg ttcctgataa
    18061 aactggcccc caagttccaa agagcaagtg acctagaaag gctccgatcc aaccgagaaa
    18121 catttttcca aaacatccca ttcgctctcc acgattggtc atagcacctg ctaaaaatcc
    18181 cactaggaga ccaacgaaca tacttcctaa catattatct ccttaatttg cccaattccc
    18241 attacggaaa agaggtaccc gcgttccatc ctcacgaata ccatcgatat ccatttggtt
    18301 agaaccaatc ataaagtcta cgtgaacatc tgaacggtta agccctgcag cttcaagctc
    18361 ctcttcgctc atctccgctc catcaacaac gctagtcgca taggctgcac cgatagccaa
    18421 gtggtttgac gcattttcat cgaaaagggt gttaaagaag gtaatgcctg actgagaaat
    18481 tggacttgga tctggtacca aggcacattc acccaaggca cgcgcacccg cattttcaaa
    18541 gacaaggtct ttcataacct gatcaccctt ctcagcagtg atatctacga tttgtccatc
    18601 cttaaaggtc accttaatgc cttcaatgat atttccgttg tagctaagcg gttttgtaga
    18661 agtgacataa ccatctgcac gacggaagtc aggcgctgtg aagacctctt ctgttggcat
    18721 atttggcaag aattcttcgc cctgtgcatt gacagcacca gctgattccc aaacgtggtt
    18781 ctttggcaaa ccaagtgtta aatctgttcc tggcgctgtg tagtgaaggg ctgaaaattg
    18841 ctccttatta agcatatcgg ccttgctctt gagaatggct gcatgttcct cccaagcctt
    18901 aacaggatct gcttcgtaga cacggcaagt tttgaaaatt tggtcccaaa ggaaatcaac
    18961 tgcttcttcg tcgctcgcag catttgggaa gactttctta gcccactcaa gtcctgctgc
    19021 agctgctaca gtccagctaa ccttgttaga ttgagttgcg atacgcatag gcttcatggc
    19081 aagtcccata gctttagcag aagctgaaag cttgtcagcg tccactccgt tcaaggcacc
    19141 tggatcagat gaacgaactc caagacggct agccttattc tccaagagat agttcatctc
    19201 agcaatcttg tattctggca cattgtccaa acgctccatc ggggcatgga ggaatttctc
    19261 acggttaatc acatcatctg tccactgaac gatgacctca tgcgcaccca aggcataagc
    19321 ttctttcacg attagatgtg ccaattcacg ttgctccaca tcaatagaga gagccaaagt
    19381 gtgaccaggt tgcacgttaa ttccgttcgc aaccaacaat ttcgcatatt tttctagatt
    19441 ttctttaaaa tttggtaaaa ccattctgtt ttctcttttc tatttttatt tttctttcaa
    19501 agcagaaaag attcctgcta aagcaatagc acctgacaag agtgctgtcg atagaagaat
    19561 tgtacgatca gcaagttcta attgatattc aaataccttc ttagccggct tatcttccgc
    19621 aaatattctt agtttcatga gaaccccctt aaaatagatt aaaataaatc actgtgactg
    19681 cctgtcctca gcaaatttaa aatcaattcc gacttgtcta ctttataaac caaaagccaa
    19741 tctggctggg tatggcattc acgaactcct tgaaaatgct tggatgccgt caatgaatga
    19801 tcacgatttc tggcaggatg ttctttttct tgaaccagaa aattcaaaac ttcttctaat
    19861 aattctgcct tcaaaccacg cttcatagcc aacttaaaat cttttttaaa ctgtttatga
    19921 taacgaatct taagcacgta agtcctccat caaatctgag actgattcaa aagactggct
    19981 catattacga ttttggtcta aatccgttaa cgcttggagc aacttccgat tttcgtctag
    20041 tctaacatca aaaggtaatc cctgatattg aattgcctga cgaaggaaaa tattaatagc
    20101 tgttgtcata tccattccca gattactaaa cacctgttgg gcctgctcct taacctcact
    20161 atccagacgg atgcttatac tcatctttga catactctca ccctctttcc atagactatt
    20221 ttaacaaaaa agaaagctaa tgtaaatcta ttggatatac gttagcctct tttaatagat
    20281 tattaagcaa ttttttaaaa caactcatca aacaaactca actggttatc ctctggcata
    20341 tttccaagaa tacccatctc atccatcttt tcaaccaagg ttgatgagag tccaccacgc
    20401 ttgcgtagtt ctgttttaga gaggaattct ccctcttcac gcgcccgcac cagttgcttg
    20461 gcaacgttct ctcccagacc atccattgct acaaatggtg ggataagggt atccccgtcg
    20521 atgaggaact ctgtcgcctg actacagtag agatctaatt taccaaactt gaaacctcgt
    20581 tcccacatct cattgacaat ctcaagagtt gtatagagat cgatttccac attagaggct
    20641 tcattgttct tccgtttttc agagatttct tccattctgc gcttgatgac ctccaagccc
    20701 gcacccatgg tcttgatatc aaaagcctta gcacgaatgg agaagtaagc acagtagtaa
    20761 taaataggat ggtgaacctt gaagtaagct acacgcaagg ccatcataac gtaggctgcc
    20821 gcatgggcct tagggaacat gtacttaatt ttcccacagg attcgatata ccactctggc
    20881 accttattag ccttcattgc ttcgatatag ccatttctct cctcttctga aatctttagc
    20941 cacaaaccct tacgtacccg ttccataatg gtaaaggcca tcttaggttc cagacccgca
    21001 tgcatgaggt aaaccatgat gtcgtcccga caaccgataa cagtcgatag gtccgctatt
    21061 ccttgcttaa tcagatcctg agcattcccc aaccaaacat cagtaccgtg ggacagacca
    21121 gacagctgaa gcaattccgc aaaggttgtc ggatgggttt cgtctaccat tccacgtacg
    21181 aaatttgttc caaactctgg aatccccaac atacccgtag gcgttccaat ttgttcaggt
    21241 gttaccccta gcacatcagt cccagaaaag agtgccatca cgccttcgtc atccatagga
    21301 attttattag ggtcaatacc agacaaatcc tgaagttttc gaatcatagt cggatcatca
    21361 tgtcccagta catcgagttt gaggacgttc tcatcgatat cgtggaagtt aaagtgagtg
    21421 gtctgccatt cagccgtgac atcatctgct ggatactgga caggcgtaaa atcgtagaca
    21481 tccatgtagt tcggaataac aacgattccc cccgggtgtt ggcctgttgt ccgcttgaca
    21541 cccgccgctc cttgagcgag gcgttctact tctgcatcac gataaaactt gccataatct
    21601 cgctcgtaac ctttgacaaa tccataggca gtcttggcag ctaccgtacc aaccgttccc
    21661 gcacggaagg catattcttc accaaagata tcacgcacat ccaagtgggc gctaggctga
    21721 tcttctcccg agaagttcaa gtcaatatca ggaaccttat ccccatcaaa accaaggaag
    21781 gtctcaaacg gaatatcctg tccgttttta ctgagtttgt gaccacagtt tggacagtcc
    21841 ttatggggca tatcaaatcc tgaaccgtac gaaccatctg tgataaactc actgtactga
    21901 cactgaccac agacatagtg aggagagaga ggattgacct ccgtaatccc aatcatggtc
    21961 gcaacgaaac tagatccgac agacccacga gaaccaacca aataaccccg ttcattagaa
    22021 cgttgcacca gcatctgcga tgccagataa atcacagcaa atccattccc cagtatggat
    22081 gttaattctt tttcaatccg caaatcaaca atatctggca gcggatttcc ataaatctca
    22141 aaagctttct tataggtcaa ctcagcaact gtttcttcag ccttgtcgat gaaaggcgta
    22201 tacaagtcac ccttaacgac ttcaacggat tcaaatattt ctgccaaggc attggtgttt
    22261 tcaataacca gtttacgagc cagttcctct cccaaaaagg caaattcatc caacatctca
    22321 ttagtcgttc gaaaatgagc ctttggaagt ggtgctggtt gggcatgttc accatgaccg
    22381 atagttcgat taatcatcgc accctgtccc aaactacgga cgataatttc acgataaatc
    22441 tcttcttccg gttcgatata gtgaacattt cccgtagcca gaacaggctt gccaaggcgg
    22501 tctccaacct ctatcaaact cttgataatg gtctggagtt cctccatatc cttgacctgc
    22561 tctttggcaa tcaagggtgc atagatagcc ggtggcatga cctcgataaa atcataatac
    22621 ttggccacct caaccgccgc atccacacct tgagaaacga ccacgtcaaa aacttcaccc
    22681 tctgaacagg ctgaacctaa aatcaagccc tctcgatggg catctagaac cgttctcgga
    22741 atccgtggca ctccttcaaa atacttggta ttagacaagg aaaccagctt aaagatattt
    22801 tttagaccta cctgattctt gacatagatg gtcgcatgct tgatccgagc ttttttgtaa
    22861 gaatctggac tgattagatc aatgttgagt ctagctaaat cggtcacacc atgtttttct
    22921 gctacctctt tgataaagat gaaaagcaga cgaccagtcg cttccgcatc gtagttggcc
    22981 atgtggtgat gttccaaggc cacaccaaaa cgcttggtca aaggccccaa accatggcgt
    23041 ttatactcag gatagaggtt tctagcaaac tccagcgtat caataactgg ctgactaatc
    23101 tttggaagat catgccgctc ataattagca ttcataaagc caacgtcaaa ggtagcattg
    23161 tgggcaacta ggaccgtatc cttgcaaaat tcttggaatt cttgcaaaac ttgttctagt
    23221 ggtttggcat ttttgacatg atcatctgta attccagtta actctgtagt aaaggctgac
    23281 aagggatgcc caggattgat aaattcatca aattcagcaa taacattccc cttgtacatc
    23341 ttagaagccg caacctgaat caagtcatta tagatagctg aaagtcccgt cgtttccacg
    23401 tcaaagacca cgtaggttgc ttctgacaag tccatctcca cttcgttata gacgataggg
    23461 acacggtcct ccacgatatt ggcttccatc ccatagatca gctggattcc cgctttctta
    23521 gccgccttat agccatgtgg aaaggactgg acattcccat ggtccgtgat agcaaccgcc
    23581 ttgtgtcccc acttagcagc tgttgcaaca atctcttcga cctctggcaa agcatccata
    23641 gtcgacatgt tagtatgagc atgaaactca acccgacgct caccttctgg catcaaatcc
    23701 ttccgctcat agtgaacaac ttcctgcaga tcctgtacgt tcatagtcaa atcgcgtgtg
    23761 aagttattca tctccacatt ccctcgaact cggagccaag aattcttctt gatgaggtca
    23821 aacttctggg cctcttcctc gtttttaacc cacttttgca tagaaaaact tgaagtatag
    23881 tccgtcattt taaagttgat taaaacacga cctgttctag tcactttttg ctccacatca
    23941 aaaacaaccc cttcaaatac cagacgattt tcctctgtcg tcacttcgat cataggagta
    24001 atctccgcct tatccagctt gggtttagct gcagcttttt tcgcttgaaa atcaaaggct
    24061 ggtttctctt ccgctggagg aggtgccatc tgctccagtt gttccatagc acggagcgct
    24121 tcctcattgg cagcttgaac aatctgctca ttttcagcat gaaaggcctc ttcctgctct
    24181 tgggtcagga catcattctt ctcgacttga cagttaaaag ttggaaaacc aaacttttca
    24241 agttgtttgg ctaaattagg aagatgattc ttcttaaaat gttccttatc aatcgcttca
    24301 gatccttcaa taaatagctg attaccctca gcacgaactt gcaaattttg ataaagggac
    24361 ttaaaacctt gactagcaca tggaccttca gagaaagcct ccctatagta ggactgcaag
    24421 agctgatttg aaaattcttg agaccgagcc ttaatttcaa aaacagcttt attgcctgtc
    24481 ttagaaaatt cttcgctcaa acctttcttt aattctaaaa agatttcaat cggtaaaata
    24541 ttagaaaata cgaaatgaaa ctcccatacc ttactaattt tatgaaccac aactcgctca
    24601 atattggcct gtgctaaagc aggagcctgt ctcatttcag caggcatccc caattgattc
    24661 atcaaaattt caaaactatt tgacattcat tttcctcaca ttattcttct actattttac
    24721 catatttaga ggtattttct aaagacaaaa ggaagccact aagtgacttc cttctagagt
    24781 gaggacggat tagtcttcac ctttattttt cttaataatt tcttcttgta ctgacttagg
    24841 tacatcttcg tagtggtcaa ataccatcat gaatgtacca cgtccttgag atgcagaacg
    24901 aagaactgtt gcgtaaccga acatttcagc aagtggaacg taagcacgaa cgatttggct
    24961 gttaccgtgt gcttccatac catctacacg tccacgacga gcagttacgt gacccataac
    25021 atcaccaagg ttttcttctg gaacagtgat tgttacaagc atcattggtt caaggatagc
    25081 tggttgtgct gatttagcag cttctttaag ggaaagtgaa gccgcaatct tgaaggcagt
    25141 ttcagatgag tcgacatcgt gatatgaacc atcataaagc ttagctttaa cgtcaaccat
    25201 tgggtaacct gcaagaacac cgttagccat agattctacc aaaccttttt caaccgctgg
    25261 gataaattca cgaggaacca caccaccgac gattgcgttt tcgaattcga atcctttacc
    25321 ttcttcgttt ggagtaaatt caatccatac atcaccgaat tgacctttac caccagactg
    25381 acgtttgaag aatccacgtg cttgagtaga agcgcggaat gtttcacggt aagatacttg
    25441 aggagcacct acgttcgctt caactttgaa ctcacgacgc atacgatcaa caaggacgtc
    25501 aaggtgaagt tcacccatac ctgagataac tgtttcacca gtttcaacgt ttgtttcaac
    25561 gcggaatgtt ggatcttctt cagccaattt ttgaagggcg atacccatct tgtcttggtc
    25621 agctttagat tttggctcaa ccatcaattg gataactggt tctggaacgt tgattgactc
    25681 aaggatgatt ttagcttttt catctgtcaa tgagtcacca gttgtagtat ctttcaaacc
    25741 aacggcagca gcgatatcac ctgagtaaac agtgtcgatt tcttgacggc tgttagcgtg
    25801 catttgaagg atacgtccga tacgttcacg tttaccttta gaagtattca atacgtatga
    25861 acctgattga agaacacctg agtaaacacg gaagaatgtc aaacgaccta cgaatgggtc
    25921 agtcatgatc ttgaaggcaa gagctgcaaa tggctcttcg tcagatgctg gacgaatttc
    25981 ttcagcgtct gtatctgggt taataccttt gattgctggg atgtcaagtg ggcttggaag
    26041 gtagtcgata accgcatcaa gcatcaattg aacacctttg tttttgaagg ctgaaccaca
    26101 caatactggg aagaattcaa cgttgatagt cgctttacgg ataccagctt tcaattcttc
    26161 gttagtgatt tcttcacctt cgaggtattt catcatcaat tcttcgtcag tttcagcaac
    26221 tgcttcaatc aatttttcac ggtattcttg agcttggtca aggtattcag ctgggatgtc
    26281 ttcttcaagg atatccgtac caaggtcgtt agtatagatt tcagctttca tcttgatcaa
    26341 gtcaatgata ccacggaagt catcttcaga accgattggc aattggattg ggtgtgcatt
    26401 tgcttgaaga cgatcgtgaa gtgtgcttac agagtaaagg aagtcagcac cgattttgtc
    26461 cattttgttg gcaaatacga tacgtggaac tccgtactca gttgcttgac gccaaactgt
    26521 ttcagtttga ggctcaacac ctgattgtga gtcaagaacg gtaaccgcac catccaatac
    26581 acgaagagaa cgttgtactt cgattgtgaa gtccacgtgt cctggtgtgt cgatgatgtt
    26641 tacgcggtgg ttgttccatt gagctgtcgt cgcagcagat gtgatcgtga taccacgttc
    26701 ttgctcttgc tccatccagt ccatttgtga cgcaccttcg tgagtttcac cgattttgtg
    26761 gattttacca gtgtagtaaa gaatacgctc agtagttgtt gttttaccgg catcgacgtg
    26821 agccatgata ccgatattac gagttttttc aagtgaaaat tcgcgtgcca tgaggtttgt
    26881 ttctcctatt tatttttgat ttctattcta ttataacacg attttaataa aaacggatag
    26941 gcaggaccta cccgttctca atgttttcat gctattgttg gtttcaactt acgagatggt
    27001 aagctgagtt atagctaata ctaatcgatt tagctaattt gaacccgggc taaagttagt
    27061 tagccgatgt gagctggaac gggatgctgc gtgaaaaaga taaaactcct tgtattcgtc
    27121 gaatactgcg tcagtttcct atttttacct tgcatcctta ccgttcctag catcatgatt
    27181 tagttgagct caagctaaaa gtctggagaa aaagatgaat ctcattggtt gcaaccgcaa
    27241 cctgcttcga ttccctattt tctctgggac tttcttaacg ctttcgcatc ctatcttacc
    27301 aacggaagtg tgcgaatgca cggttagctt cagccatacg gtgagtatct tcacgtttct
    27361 taactgctgc accagtgttg ttagcagcat ccaagatttc ttttgcaaga cggtcttgca
    27421 ttgtgtgttc accacgaaga cgagcgattg ttaccaacca acgaagtcca agtgttgtac
    27481 gacgttctgg acgaacttca actgggactt ggtagttaga accaccaaca cgacgtgcac
    27541 gtacttcaag tacaggcatg atgttttcca tagctgtttc aaatacttca agtgcatcgt
    27601 tgccagtagc ttctttgatt tgctcaaaag caccgtaaac gattgaagca gcagtaccac
    27661 gtttaccatc aagcataacg cggttgataa gacgagtaac tagttgtgaa ttgtatagcg
    27721 gatctggcaa tacgtcacgt tttggagctc tatttttacg actcatttct ctttatcccc
    27781 tttccttatg cttttggacg tttagtaccg tatttagaac ggccttgttt acgatcgtta
    27841 acacctgcag tatcaagtgc accacggacg atatggtaac gtacccctgg aaggtctttt
    27901 acacgtccac cgcgaagaag caccacgctg tgctcttgca agttgtgtcc gatacctggg
    27961 atgtaggcag taacttcgat aaggttgctc aaacgtacac gagcgaattt acgaagggct
    28021 gagttaggtt ttttaggtgt cattgttcca acacgagttg caacaccacg tttttgtggt
    28081 gaagaaacgt ttgtttgaac ttttttatga ctattgtaac caacgttcaa agctggtgat
    28141 ttagattttt ctacttttga tttacgcggt ttgcgaacca attggttaat tgtaggcatc
    28201 tacattctcc tgtgtttttt tatttttggt gatgatacac ttggtgacag atatcatctg
    28261 tgtgtacttt tgcaacattt gtcagcacgt ccctgtacac tcttgagaga ccaaaagtaa
    28321 aaagtaccgt ctattattgt aacaaaattt tcccttgctt gtcaagatat ttttcttttt
    28381 tattggtaat gttagagatc aatttctgaa taaaaatagc tgagaacaca tcatcttcct
    28441 aataacacgg cttggcttac gtgacatttt tatctccgtc atttatactg atatataaaa
    28501 tagtacggaa aacttctcaa aagtaagaat ttctttcaca aatcaaagaa aacgcttgca
    28561 tattgtttta ctacatgcta tactgatata gaaatttatt gattggagaa tcattatgag
    28621 aaaaacacca tctcacactg agaaaaaaat ggtctacagc atccgttccc tcaaaaatgg
    28681 aactggttct gtccttatcg gcgcaagcct tgtcttgctt gccatggcta caccaactat
    28741 ctcatccgac gaaagtacac caaccactaa cgaacccaac aacagaaata caaccaccct
    28801 tgcccaacct cttactgata cagcagctgg ctctggtaag aacgaaagtg atatttcttc
    28861 acctggaaat gcaaacgctt ccctagagaa aacagaagaa aaacctgctg caagcccagc
    28921 cgatccagca ccacaaactg gacaagatcg ttcaagtgag ccaactactt ctactagtcc
    28981 agtaacaact gaaactaagg cagaagagcc catcgaagat aactacttcc gtatccatgt
    29041 caaaaaactt cctgaagaaa acaaggatgc tcaaggacta tggacttggg acgatgttga
    29101 aaaaccatct gaaaactggc caaacggagc tttgtccttc aaggatgcca agaaagatga
    29161 ctacggctat tacctagatg tcaaattaaa gggagaacaa gccaagaaaa ttagcttcct
    29221 catcaacaat acagctggaa aaaatctaac cggcgataaa tctgtagaaa aactagttcc
    29281 aaaaatgaac gaagcttggt tagaccaaga ttacaaggtt ttctcttacg agccacagcc
    29341 tgcaggaact gttcgcgtca actactaccg cacagatggc aactatgaca agaaatctct
    29401 ctggtactgg ggagatgtga aaaatccaag tagcgctcaa tggcctgacg gaacagactt
    29461 tacggctaca ggcaaatatg gccgctatat cgacattcct cttaatgaag ccgcaagaga
    29521 atttggattt ttattactag atgagagcaa acaaggagac gacgtgaaaa tccgtaaaga
    29581 aaattataag ttcacagatt tgaaaaatca tagccaaatt ttcctaaaag acgatgatga
    29641 atcgatttac acaaatccat actatgtcca tgatatccgt atgacaggag cccaacacgt
    29701 aggcacttct agcattgaaa gtagcttttc aacacttgtc ggtgctaaaa aagaagatat
    29761 cctcaaacac tccaacatca ctaatcacct aggaaacaag gtaactatta ccgatgttgc
    29821 aatcgatgaa gctggtaaga aagtgaccta cagcggagat ttctctgaca caaaacatcc
    29881 ttatactgtt agctacaatt ccgaccaatt cactaccaaa acaagctggc gcctgaaaga
    29941 tgagacatac agctatgatg gcaaactggg agctgaccta aaagaagaag gaaaacaagt
    30001 tgatttgacc ctttggtcac caagtgctga taaggtttct gttgttgtct acgacaagaa
    30061 tgaccctgac aaagtagttg gaactgtcgc tcttgaaaaa ggggaaagag gaacttggaa
    30121 acaaactcta gacagcacaa acaaactcgg aatcacagat ttcactggct actattatca
    30181 ataccaaatc gagcgtcaag gtaaaactgt tcttgcactc gatccttacg ctaaatctct
    30241 tgctgcttgg aatagcgacg attccaagat tgacgatgcc cataaagtgg ctaaagccgc
    30301 ctttgtagat ccagctaaac tcggacctca agacttgact tatggtaaga ttcacaattt
    30361 caagactcgt gaagacgccg ttatctacga agctcatgtg cgtgatttca cttcagatcc
    30421 tgccattgca aaagacttga ccaaaccatt tgggactttt gaagccttca ttgaaaaact
    30481 agactatctc aaagacttgg gtgtaaccca tatccagctc cttccagtct tgtcttacta
    30541 ctttgtcaat gaattgaaaa accatgaacg cttgtctgac tacgcttcaa gcaacagcaa
    30601 ctacaactgg ggatatgacc ctcaaaacta cttctccttg actggtatgt actcaagcga
    30661 tcctaagaat ccagaaaaac gaatcgcaga atttaaaaac ctcatcaacg aaatccacaa
    30721 acgtggtatg ggagctatcc tagatgtcgt ttataaccac acagccaaag tcgatctctt
    30781 tgaagatttg gaaccaaact actaccactt tatggatgcc gatggcacac ctcgaactag
    30841 ctttggtggt ggacgcttgg ggacaaccca ccatatgacc aaacggctcc taattgactc
    30901 tatcaaatac ctagttgata cctacaaagt ggatggcttc cgtttcgata tgatgggaga
    30961 ccatgacgcc gcttctatcg aagaagctta caaggctgca cgcgccctca atccaaacct
    31021 catcatgctt ggtgaaggtt ggagaaccta tgccggtgat gaaaacatgc ctactaaagc
    31081 tgctgaccaa gattggatga aacataccga tactgtcgct gtcttttcag atgacatccg
    31141 taacaacctc aaatctggtt atccaaacga aggtcaacct gcctttatca caggtggcaa
    31201 gcgtgatgtc aacaccatct ttaaaaatct cattgctcaa ccaactaact ttgaagctga
    31261 cagccctgga gatgtcatcc aatacatcgc agcccatgat aacttgaccc tctttgacat
    31321 cattgcccag tctatcaaaa aagacccaag caaggctgag aactatgctg aaatccaccg
    31381 tcgtttacga cttggaaatc tcatggtctt gacagctcaa ggaactccat ttatccactc
    31441 cggtcaggaa tatggacgta ctaaacaatt ccgtgaccca gcctacaaga ctccagtagc
    31501 agaggataag gttccaaaca aatctcactt gttgcgtgat aaggacggca acccatttga
    31561 ctatccttac ttcatccatg actcttacga ttctagtgat gcagtcaaca agtttgactg
    31621 gactaaggct acagatggta aagcttatcc tgaaaatgtc aagagccgtg actatatgaa
    31681 aggtttgatt gcccttcgtc aatctacaga tgccttccga cttaagagtc ttcaagatat
    31741 caaagaccgt gtccacctca tcactgtccc aggccaaaat ggtgtggaaa aagaggatgt
    31801 agtgattggc taccaaatca ctgctccaaa cggcgatatc tacgcagtct ttgtcaatgc
    31861 ggatgaaaaa gctcgcgaat ttaatttggg aactgccttt gcacatctaa gaaatgcgga
    31921 agttttggca gatgaaaacc aagcaggacc agtcggaatt gccaacccga aaggacttga
    31981 atggactgaa aaaggcttga aattgaatgc ccttacagct actgttcttc gagtctctca
    32041 aaatggaact agccatgagt caactgcaga agagaaacca gactcaaccc cttccaagcc
    32101 tgaacatcaa aatgaagctt ctcaccctgc acatcaagac ccagctccag aagctagacc
    32161 tgattctact aaaccagatg ccaaagtagc tgatgcggaa aataaaccta gccaagctac
    32221 agctgattca caagctgaac aaccagcaca agaagcacaa gcatcatctg taaaagaagc
    32281 ggttcgaaac gaatcggtag aaaactctag caaggaaaat atacctgcaa ccccagataa
    32341 acaagctgaa cttccaaata caggaatcaa aaacgaaaac aaactcctat ttgcaggaat
    32401 cagcctcctt gcgctccttg gtctcggttt cttactaaaa aataaaaaag agaactaaac
    32461 tagccctcct atagaaaaat cccccaagca ttatagctcg ggggattaat ttttgtacaa
    32521 tatttgttgt cctaataaac ttgattagga ttttttatta agcctctttc atagcaaaat
    32581 aagctcgtac tttgggtgca acttgtgttc cgaagagttc aatagctctc agaacctggt
    32641 catgaggcat agaaccaagc ggtagatgaa gcatgaagcg gtccaatcct aaatcctcta
    32701 tcatgcgaat caatttttcg gccacctgat ctggattgcc aacaaacatg gcgccatttg
    32761 gccctacctg ctccaaatat tgctcataac gcaattcctg ccagtgcgga cggtctttgg
    32821 aaatagcatc caccacttgc ttagtcggat ggaaataatc tttcaccgcc tgctcaccat
    32881 cttccgcaat ccacccccaa gaatgggctc ccactttcaa gtctttgtca gcatggcccg
    32941 cttcgcttcc aatctcacga taagcctgaa tcaacttttt aaaataacgt ggattaccac
    33001 caataatagc atatacaatc ggtagaccag cctgagcaat cttcactgtt gattcgacat
    33061 gaccacctgt agctatccac aagggcaatt tgtcctgaac tggacgagga taaacttctt
    33121 taccagcaat cgtttgagtc aatcgacctt gccagtctaa cttggtcttt tcattgacta
    33181 actgaagcaa gtctaatttc tcatcaaaaa gagagtcgta gtctttcaag tcataaccaa
    33241 acagagggaa agattccgtg aaagagcccc ttccagccat aatctccgat cgtccatttg
    33301 acaaagcatc gatagtggca tactgttgga acaaacgaat cgggtccatg cttgacagaa
    33361 tgctgactgc actggtcaaa cggattttct tggtattgac tgccccagcg gccagaacaa
    33421 tctctggggc tgatactgca aaatccgccc gatggtgctc accaatccca tatacatcca
    33481 aaccaacctt gtcagccagc tcaatctctg ccaccaactg gcgaatgcgt tcagcatgac
    33541 tgtaagtttg tccagtccct tcaagctccg ttatttcccc aaatgttgaa attcccaatt
    33601 ctaccattgt gattctcctt atctatctct gtacttcaat ttgaaaaatt attctaacac
    33661 gaatcttgag tacaagcaac cgatttgctc attagaaaaa gcctagataa ctagactttt
    33721 ttagcttatt ctaccgttac tgacttggca aggttacgtg gtttgtccac atcgaggcca
    33781 cggtggaggg ttgcaaagta agcgactaat tgcgttggta cgaccattga aattggtgag
    33841 aggtatggat gtacggtcgt aaggacgata tcgtcggtat ctttggctac attctcttct
    33901 gcgatagtga ggactttggc accacgggct gcgacctctt ggatatttcc acgagtatga
    33961 ttggcaagaa ctggatctga caagagagcc aaaacaggcg ttccttcttc aatcaaggca
    34021 atggttccgt gcttgagttc tcctgcagca aagccttcac actggatata agaaatctct
    34081 ttgagtttga gacttgcttc catggctacg tagtaatctt gaccacgtcc gatgtaaaag
    34141 gcgttacgag ttgtttcaag aagttcacga accttgactt caatggtttc tttctctgaa
    34201 agagttgatt cgatagactg agctacgatt gacaattcat gaaccaggtc aaaggcttgc
    34261 gctttagcat taccatttgc ttctccgact gcttttgcaa ggaaggcaag ggctgcgatt
    34321 tgcgctgtat aggctttagt tgatgccacg gcaatttcag gacctgcgtg aaggagcatg
    34381 gtatagttgg cttcacgtga gagggttgaa cctggaacgt ttgtcactgt taagcttgga
    34441 attcccattt cattagcctt gaccaaaact tgacgactat ccgctgtttc accagattgg
    34501 ctgataaaga tgaagagtgg tttcttgctg agaagtggca taccgtagcc ccactcagat
    34561 gagattccaa gttcaactgg tgtatctgtc aattcttcca acattttctt agaagcaaat
    34621 cctgcatggt aagatgttcc agctgcaagg atgtagatgc ggtctgcgtc ttgaacagcc
    34681 ttaatgatat ctgggtctac gacaacttga ccagcctcat ctgtgtaggc ttggatgagt
    34741 ttccgcataa cagttggttg ctcgtcaatt tccttgagca tgtagtaagg gtaagttccc
    34801 ttaccgatat ctgacaagtc aagttcagca gtgtagctag cacgctcacg acgatttcca
    34861 tcatagtctt gaacttccac actatcagcc ttgacgatta ccaactcttg gtcatggatt
    34921 tccatgtatt ggttagtttc acgaatcata gccatggcgt ctgagcagac catgttatag
    34981 ccttctccaa gaccaatcaa aagtggtgat ttatttttag ctacgtagat gacttcagga
    35041 tcttgtgagt caaccaaggc aaaggcataa gaaccacgga tgatgtgaag ggcttttttg
    35101 aaggcttcaa gaactgagag cccttcttct tccgcaaatt ttccaatcaa atgaacggct
    35161 atttcagtat ctgtctgccc cttgaagtgg tgacctgcaa ggtattcttc cttgatttca
    35221 agatagttct caatcacccc attatgcacc aagacaaaac gttccgtctc agagcggtgt
    35281 gggtgagcat tgtcctcagt tggttttccg tgagtagccc aacgagtatg tccgatacca
    35341 gttgttccct caacaccagc tgtcttggca gacaattctg caatacgacc aaccgccttc
    35401 accaaatggt tatcagcacc atctaggaca aaaattcccg cagaatcata gccacggtat
    35461 tcaagctttt caagcccttg aatcaaaata tcagttgcat ttgtgtttcc aacaacacca
    35521 acaattccac acatagtata tacgacacag gcaagctgtg ctttctcctt aaaattggta
    35581 tagtctaatt catcttttat agaatcagca aaaacagtat atacttgttt ctttcacttg
    35641 tcaagagtaa aaattggtat agttcaaatt aagctcctgt aagcataaaa actctgaccg
    35701 attgggataa tcagtcagag tcctttttaa aatccattat tatcgcttaa ttctttgaac
    35761 cagtggcctg atttcttcag acgacgttct tgcgtttcca agtctaattc gaccaaacca
    35821 tagcgatttt tatagctgtt gagccatgac cagcagtcaa taaaggtcca aatcaagtag
    35881 cccttacagt tggcaccatc ttcaatggca cggtgaagtt cacgaagatg accttttaca
    35941 aagtcaatac ggtaatcatc ttgaatcatt ccatcttgac ggaatttttc ttccccttca
    36001 acacccatac cattctcagt caacatccac tcaatattgc cataattttc cttgatattt
    36061 tgggcgatgt cataaatccc ttgctcataa atctcccaac cacggtgaga attgatttta
    36121 cgtccaggca tcacataagg ctcgtaaaaa tgttctggta agagtggact ctctggatgc
    36181 ttagcaaatc gaggagccat aacacgcaaa ggttgatagt agttcacacc aaggaagtcc
    36241 accgtattat cacgaatgag ttccaactct tcctctgtag catcaggtaa aagaccgtgt
    36301 tcatgcaaga tttctaccaa ctcctgtgga taagtcccca agacagatgg atctaagaaa
    36361 gattgggcct gaaaaagggc cgcaatacga gctgccttga catcagcagg atgctggcta
    36421 cgtggataag ccggtgtcaa gttgaggaca atcccaatct tggaatcagg caaaagttca
    36481 tggcaagcct taacagcccg gctgctggcc aattgtgtat gataggctac cttaacagct
    36541 gcctctgcat ccaccttatg tggataatgg gcatcataaa aataaccaaa ttctacagga
    36601 acgatgggct cgttaaaggt aatccattga tccactaaat ctccataagt ctcaaaacaa
    36661 aaacgagcat agtcttcata ggctgagact gtcgccttat tttcccaacc atcaccatcc
    36721 tcttgaaggg caaaaggtaa atcaaaatga tagagattga ctaacagacg aattccttta
    36781 gccttaatag cctcaaagac cttacgataa aaatccacac cttgagtgtt gacttttcca
    36841 cagccttgtg gaaaaatccg tgaccactga atagaagtcc gaaaggctgt gtgaccagtc
    36901 tctaacaaaa gctcaatatc ccgctcccaa ttttcataaa aagtcgatgt cttatctgaa
    36961 ccaatcccat tatagtaacg atttggctcc acttggaacc agtaatccca gagattgtct
    37021 cccttaccgt caccagctac acgtccttct gtctgcggtc cagaagtaga ggatccccag
    37081 acaaaatcct ttggaaatct tagcatacat ttacctcttt atctactcat ttctcccatt
    37141 atacagaaaa aacaaggtaa aaactagtta cattttttcc ttgtttttct tctgattata
    37201 gtttttattt cttgcttagg atttcaagcg tttcaagcac gttatctgca tgaacctcaa
    37261 tggtgtcacc agttgccttg atcttaactt ctacaatgcc atcggccgct tttttaccaa
    37321 cagtgatacg gattggaaga ccaatcaagt cactatcgct aaatttaaca ccgacacgtt
    37381 cgttacggtc atctgtcaag acttcataac cagctcccat caagcttgct tcaagttttt
    37441 ctgtcaaggc ttgcgcttct tcatccttga cattgacagt aatcaaatgc acatcaaatg
    37501 gtgccaattc tttagggaaa ttgattcccc aagcgtaacg gtattcacct tttggcgttt
    37561 tgttaacaaa gaggcgagcg tgttgctcca tcactgctga aagaagacgg ctgacaccga
    37621 taccgtaaca tcccatgatg attggcacag cacgaccatt ttcatccaag acatctgctc
    37681 ccatgcttgc tgaatagcga gttccgagtt tgaaaatatg accgatctca ataccacgcg
    37741 caaagttaag gacaccttgt ccatctgggg aaatttcacc ctcacgaact tcacggatat
    37801 ccacatattc tgcagtaaaa tcacggcctg ggttcacacc agtcaagtgg tagtcatctt
    37861 cgttagcacc gacaactgca ttgcgaacat cttgtacctt acgatctgca ataattttaa
    37921 tattctctgg caaaccaact ggtccaagtg aaccaaatcc tgcttgaaca acattcgcca
    37981 cttcttcttc gctagcaacg tcaaagaaat ctgctcccaa gtgatttttc aacttgactt
    38041 cgttgagttg gtcatttcca actagaaggg ctgcaacaag ctcaccatct gcaatgtaga
    38101 agagggtttt aatcgtttgt tcttctggaa cattgaggaa ggctgcaact tcatcaattg
    38161 atttaacatc tggcgttgca acacgagtaa cttcttcttc agcgacaaca cggttgcttg
    38221 gtttgtactc gtttgttgcc atttctaagt tagctgcata gctagactca cttgagtaag
    38281 caatggtatc ttcaccagag actatccatt tgagcaattc tgccttgatt tcttcttgca
    38341 cttctgcagg aatttcgtca aatgaggcaa ctgacttgtc caagacaacc cagcggtcaa
    38401 ggtctgtacg agcagatgta atggccataa attcttggct atccttacca cccatggctc
    38461 caccgtcacc aataatagcc ttgaagtcta aaccactacg agtgaaaata cgctcatagg
    38521 ctgctttgta ctcatcataa acactatcca aactatcata gttagcgtgg aaactataag
    38581 catccttcat gataaactca cgtgtacgaa gaagtccatt acgcgggcgt ttttcatcac
    38641 gatacttggg ctgaatttga taaaggttga gtggcaattg cttgtaagat ttaacagaat
    38701 cacggacaat agctgtaaag gtttcttcgt gagttggacc taagataaag tctgattttt
    38761 cacggttttt tagtttgtaa aggtcttcac cataggtttc gtaacgacct gattcacgcc
    38821 acaattctgc actaagaagg gctggagcca acatctcaac agcaccaatc ttttcgaatt
    38881 cttggcgcat gatgttttta gctttttcaa tcacacggtt ggcaagtggt agataagaat
    38941 aaacacctgc tgaaacttgg cgaacataac cagcacgcaa cataagagca tggctgataa
    39001 cttgagcatc gcttggcatt tcgcgaagcg ttgggatagg cattttactt tgtttcataa
    39061 tattcctcga ttatctaaaa aagagtcgca taatgtcatt ccaagtcaca gcaatcatca
    39121 agacaaccat gatgaccact ccggccaagg tgacataggt ttcaatttct tgtttcaatg
    39181 gtttgcggcg gatggcttct aggatattga gcacaatctt accaccatcc aaggctggaa
    39241 tcggaataag attaaaaatc ccaatattga tggaaatcat tgccaagaag tacaagatat
    39301 tttcaattcc atttttagca gcatcactac ttgccttaaa gatagcaaca ggtccaccca
    39361 acttgttcaa atctggttgg aaaatcagat ttttcagagc tgagagaatt cggagagctg
    39421 agtcagcagc agttgtaaaa ccacctacaa acatggatag aaaatctgac ttaacccccg
    39481 gttgaacacc tagaaggtaa cgaccttgac tatctttggg tgtaacagtg acttgtttgt
    39541 cactcccctt ttcagaaata gtcacatcca aagtcggtgc cgtcttatct ttggtttctg
    39601 tttccacagc ttggatcaag ctttcccagt tgctaacctc atgtgagcca atcttggtaa
    39661 tttgtgccat ttctggtact cctaccttgg ccaaggcacc ttggggcatg atatggaact
    39721 gattggtatc aacatctctg acaccaccct gcataaagat taaaacccaa aaaacaacga
    39781 cacctaagat aaaattgttc ataggacctg caaaattggt aatcagtttg ccccagatag
    39841 tcgcattttg atattgaaca tctaaaggtg caatccgaac ctcagtacca tctgcttcca
    39901 caaccgttgc atcgtgatcc actgcaaatg ttttttcttc ttccagaacc aatcctttga
    39961 taaagagctt gtcttcaaaa tcaaactggg tcacctgcat agggagggct gtttgatcca
    40021 attttttacc tgagagattg atgcgtttaa ccttaccatc atcagcaagt gtcaaactaa
    40081 caggcgttcc tgtcttgatt tcagttgtat catcacccca accggccatg cggacatagc
    40141 cacccagagg caagattcga atggtatagg ccgttccatc cttgccaatg tgagcaaaaa
    40201 ttttaggtcc cataccgatg gcaaattcac gtactaaaat ccctgatttc ttggcaaagt
    40261 agaagtgacc gaactcgtgc accactacaa taatcccgaa aaccagaata aaggttaaaa
    40321 ttccgagcat agcgtttcct ccgtcttttg attaaaagag tccaaataag tgcatgattg
    40381 gaaatacaag caacatacta tcgaaacgat ccaaaacacc accatgtcca gggataaatt
    40441 tcccagaatc cttaacacca aaatgacgtt tgatcgaact ttctagtaaa tcaccaaatt
    40501 gtccagcaat gctaaagaaa atagcaaaga ctgacatctt gtaaattcca tatggaagag
    40561 caactgtact gtcaactatc ataaggataa tggttactaa aattgctcct aaaataccac
    40621 ccaaggcacc ctcaagggtt ttattaggcg atacccttgg tgctaacttt cgtttcccat
    40681 agttcatccc aacaagatag gcaccactgt ctgtcgccca gacgatacac aaggctaaga
    40741 gagccttgtc caaacctgca acacgagcat ctagtaaagc attaaatcca aagcccacgt
    40801 agaagctcat agcaagaggg aaaaccgcat cctcaatcgt ataagacttg ctaaaaacgg
    40861 tcgttcctaa catgattgaa atcaaaacac tataggcaac cacattccca tcaactggca
    40921 aaaaagtcag gtaattctcc aagggaatgg tcaatgcaaa ggttgcaaag agggtcaaga
    40981 ggccctccat cgtcatggtc tctagacctc tcatcttcaa aagttcatgc atggctagca
    41041 tggctatgat tccgattgct atctgaagca agaggccccc aatcattaaa attggtagga
    41101 aaatagccag ggcaatccct gcaaacaagg ttcttttctg taaatcctgg gtcatatttc
    41161 ctcctaaact cctccaaatc ggcgatgacg acgattatag gcaagaatag cttcctgcaa
    41221 ggccgcttcg tcaaaatcag gccataaggt gtccgtaaaa taaagctcac tataggctcc
    41281 ctgccatgga aggaaattgc tcaaacgtaa ttctccacta gtacggataa tcaagtctgg
    41341 gtctcgtaag tccttaggca aatgctgagt aaagagatag ttaccaatca attcctctgt
    41401 gatgtcacct gggttgattt tggcatctaa aacatcctgg gaaatcaact taagcgcctg
    41461 tgtaatctca gcacgtccac catagttaag agcaaaatta agaatcaatc ctgtgttgtt
    41521 cttagtcaat tcctcagcct tggttaaagc ttcaaaggtt tgcttaggca ggcggtctgt
    41581 ctccccaatc atttgaatct taacattatt cgcatgtagt tccgggacat aattatcata
    41641 aaactctact ggcaagttca tgataaactt gacttcctga tctggacggg tccagttttc
    41701 cgtagaaaaa gcatagaccg taataacctt gacgcccagt ttgttggctg ccttggtcac
    41761 ggtttgcaat gcttccatgc ccgccttatg tccaaaaact cgcggttgca tacgtttttt
    41821 agcccaacgg ccattgccat ccatgatgat gccgatatga gcaggaacct gtgtcggaac
    41881 ctctacttcc acagccttat ctttcttaaa aaatccaaac atgatcttat tcctattcaa
    41941 aaatctatcg tttcattata ccatatttcc ccattttctt ctatcactaa gctatttatt
    42001 ctcaggcacc aagcccattt ttcaaaaaaa taagccgcct gattgggcga ctttattttt
    42061 atagggagat tattatgaaa aagttttagg agtttaagtt aaggtcttct taacttatga
    42121 acttagtgta cactccctag cttaaagttt ccttaagtat ttttaaaaat caaatttttc
    42181 catttctcct gccaattttt cttggataaa cgtgtttgat agagttccat tcggtcttca
    42241 ttttctaaga aatgaggagt tggacgaact tgaaaattca aaatatcctc caaaccataa
    42301 ggtacataga gttcaaaatc taattcttca ttcaagcgca gtccaactgc cgtacaccgt
    42361 tctggatact tactcatagc atcacgagaa ctggtatagg aagcagtgtg aggactgtgc
    42421 tgatgcatat agacctgatt tttcaattcc cactggtact gaggaaaatc ctctctcagc
    42481 tttttctcca gtaataaggt ttcctcataa gaaaaatctg gatcaaagaa aatcacatct
    42541 atatctgttt catgatcaaa aggggatttg tctgacaaaa gattccagat gaaatttctg
    42601 acagaacctg ctgccaacca cgagtctttc aaaccaaggt ctcggatgat cgtcagaatg
    42661 gccatcatat ctggactttc tctaaaagcc tctaagattt cttgcttatt tttcactgta
    42721 ttcataacct aagtgctcat atgccttagc agtcgccacc cgtccagacc gtgtccgcat
    42781 gataaaacct ttttgaatca agtaaggctc atacatgtct tcaactgtct cacgctcttc
    42841 ggcgatattc acagaaagag ttcctagacc aacaggtcct ccactgtaca tctcaatcat
    42901 ggtgcgaagg attttttgat ccacatagtc caaaccttca tggtcaacat ccagcatagt
    42961 caaagcctta tcggtaataa catcatcgat aaccccattc cccattatct gggcaaaatc
    43021 gcgcacgcgc ttgaggagac gattggcaat acgaggggtt ccacgactac gtagggccaa
    43081 ctcagatgct gcctcatggg tgatttccat ctcaaaaata tctgccgtcc gctcgacaat
    43141 ttctgtcaag tcagcatgag cataatactc catatgacct gtaatcccaa aacgtgcccg
    43201 tagtggattt gagagcatac cagcccgagt cgtcgcacca atcaaggtaa aaggaggcaa
    43261 ctccaaatga acactgcgac tgccttcacc agccccaatc ataatatcga tgtagaagtc
    43321 ctccatggca ctataaagca cttcttccac tgacatgggt aagcgatgaa tctcgtcaat
    43381 aaagaggaca tctccaggct ctaaatcatt caaaatcgct accaaatcac ccgctttttc
    43441 gataacagga ccagacgttt gcttgagatt gactcccagt tcattggcaa tgacaaaagc
    43501 catggttgtt ttcccaagcc ctggagggcc aaataagagc acatgatcca gcgcttcatc
    43561 ccgcatttta gcggcttcga taaagatctg aagttgatcc ttaaccttat cctgaccaat
    43621 atattcacgt aaatactgag gacggagcgt gcgttctact aactcctcat cacccatcat
    43681 ctcattatct aaaattctac tcatggctct attatatcaa aaaaaacaag ccacaaacaa
    43741 aaaagccacc tgattgggtg actcctaagt ttagcactta tgtggtataa tattatacgg
    43801 cacttctaca ccgcctacga aaggaggtga gatagcccat gatggaatta gtactcaaaa
    43861 ctattatcgg accaattgtg gtcggtgtcg ttcttcgtat agtcgataaa tggctaaaca
    43921 aggacaaata gtgtcaaaaa agacctcaag cttatttggt cgtgagcttg gggtcttttc
    43981 tagcctatga tatagaacta gtactcaatt cctttttatt atcccatagt tcacgaattt
    44041 tgtcaaaact ttacattttc ttcaaccgct gtacgacaag acggttaaga ttaagagaac
    44101 gttagggatt ctatcaattt catagaaatt ttgatttcgt aaacgaagag acaatcttac
    44161 atgtcacttc tcatttaata cgccactact agacaagcaa aatcattatt acagtagttc
    44221 cagtccttca attaacagtc acttacaatc aaattgagtt tgaactagct gaagcgacca
    44281 cagacctatt tcttagtcat attcgctaaa aaaatccccg ccaaaatctc aaaaagtccc
    44341 cgccaattcc ccgaccaaaa tccgaaaaat accgaaaaat atcgaaaaat tatttttaga
    44401 atagtcccaa aaatcctgaa atagagctaa aaaactccac ctgattcggt ggagttaagg
    44461 gagattatta tgaaaaagaa aagtttagga ttttattaaa taaagttagg aggtctttat
    44521 ttaataacta catgatacaa gacgaaactt aaaactagct taacttttct aaaattttac
    44581 tattttgcaa aaaatttcta tcaccagcac ctcac
//
LOCUS       DAVFER010000017        41133 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1105170250
            SAMEA2167659-rid19724873.denovo.017, whole genome shotgun sequence.
ACCESSION   DAVFER010000017 DAVFER010000000
VERSION     DAVFER010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2167659
            Sequence Read Archive: ERR388902
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 41133)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 41133)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928716.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928716.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 04:07:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,118
            CDSs (total)                      :: 2,073
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 120
            CDSs (without protein)            :: 120
            Pseudo Genes (ambiguous residues) :: 0 of 120
            Pseudo Genes (frameshifted)       :: 67 of 120
            Pseudo Genes (incomplete)         :: 47 of 120
            Pseudo Genes (internal stop)      :: 34 of 120
            Pseudo Genes (multiple problems)  :: 23 of 120
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..41133
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2167659-rid19724873.denovo.017"
                     /strain="1105170250"
                     /db_xref="taxon:1313"
     gene            complement(70..921)
                     /gene="srtC-3"
                     /locus_tag="VU534_000929"
     CDS             complement(70..921)
                     /gene="srtC-3"
                     /locus_tag="VU534_000929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000091736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PI-1 pilus system sortase SrtC-3"
                     /protein_id="HEU1513539.1"
                     /translation="MSRTKLRALLGYLLMLVACLIPIYCFGQMVLQSLGQVKGHATFV
                     KSMTTEMYQEQQNHSLAYNQRLASQNRIVDPFLAEGYEVNYQVSDDPDAVYGYLSIPS
                     LEIMEPVYLGADYHHLGMGLAHVDGTPLPLDGTGIRSVIAGHRAEPSHVFFRHLDQLK
                     VGDALYYDNGQEIVEYQMMDTEIILPSEWEKLESVSSKNIMTLITCDPIPTFNKRLLV
                     NFERVAVYQKSDPQTAAVARVAFTKEGQSVSRVATSQWLYRGLVVLAFLGILFVLWKL
                     ARLLRGK"
     gene            complement(908..1801)
                     /gene="srtC-2"
                     /locus_tag="VU534_000930"
     CDS             complement(908..1801)
                     /gene="srtC-2"
                     /locus_tag="VU534_000930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000370515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PI-1 pilus system sortase SrtC-2"
                     /protein_id="HEU1513540.1"
                     /translation="MDNSRRSRKKGTKKKKHPLILLLIFLVGFAVAIYPLVSRYYYRI
                     ESNEVIKEFDETVSQMDKAELEERWRLAQAFNATLKPSEILDPFTEQEKKKGVSEYAN
                     MLKVHERIGYVEIPAIDQEIPMYVGTSEDILQKGAGLLEGASLPVGGENTHTVITAHR
                     GLPTAELFSQLDKMKKGDIFYLHVLDQVLAYQVDQIVTVEPNDFEPVLIQHGEDYATL
                     LTCTPYMINSHRLLVRGKRIPYTAPIAERNRAVRERGQFWLWLLLGAMAVILLLLYRV
                     YRNRRIVKGLEKQLEGRHVKD"
     gene            complement(1788..2690)
                     /gene="srtC-1"
                     /locus_tag="VU534_000931"
     CDS             complement(1788..2690)
                     /gene="srtC-1"
                     /locus_tag="VU534_000931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PI-1 pilus system sortase SrtC-1"
                     /protein_id="HEU1513541.1"
                     /translation="MVKTKKQKRNNLLLGVVFFIGMAVMAYPLVSRLYYRVESNQQIA
                     DFDKEKATLDEADIDERMKLAQAFNDSLNNVVSGDPWSEEMKKKGRAEYARMLEIHER
                     MGHVEIPVIDVDLPVYAGTAEEVLQQGAGHLEGTSLPIGGNSTHAVITAHTGLPTAKM
                     FTDLTKLKVGDKFYVHNIKEVMAYQVDQVKVIEPTNFDDLLIVPGHDYVTLLTCTPYM
                     INTHRLLVRGHRIPYVAEVEEEFIAANKLSHLYRYLFYVAVGLIVILLWIIRRLRKKK
                     KQPEKALKALKAARKEVKVEDGQQ"
     gene            complement(3028..4209)
                     /gene="rrgC"
                     /locus_tag="VU534_000932"
     CDS             complement(3028..4209)
                     /gene="rrgC"
                     /locus_tag="VU534_000932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010963222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PI-1 pilus minor pilin RrgC"
                     /protein_id="HEU1513542.1"
                     /translation="MISRIFFVMALCFSLVWGAHAVQAQEDHTLVLQLENYQEVVSQL
                     PSRDGHRLQVWKLDDSYSYDDRVQIVRDLHSWDENKLSSFKKTSFEMTFLENQIEVSH
                     IPNGLYYVRSIIQTDAVSYPAEFLFEMTDQTVEPLVIVAKKTDTMTTKVKLIKVDQDH
                     NRLEGVGFKLVSVARDVSEKEVPLIGEYRYSSSGQVGRTLYTDKNGEIFVTNLPLGNY
                     RFKEVEPLAGYAVTTLDTDVQLVDHQLVTITVVNQKLPRGNVDFMKVDGRTNTSLQGA
                     MFKVMKEESGHYTPVLQNGKEVVVTSGKDGRFRVEGLEYGTYYLWELQAPTGYVQLTS
                     PVSFTIGKDTRKELVTVVKNNKRPRIDVPDTGEETLYILMLVAILLFGSGYYLTKKPN
                     N"
     gene            complement(4256..6253)
                     /gene="rrgB"
                     /locus_tag="VU534_000933"
     CDS             complement(4256..6253)
                     /gene="rrgB"
                     /locus_tag="VU534_000933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000836217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PI-1 pilus major pilin RrgB"
                     /protein_id="HEU1513543.1"
                     /translation="MKSINKFLTMLAALLLTASSLFSAATVFAAGTTTTSVTVHKLLA
                     TDGDMDKIANELETGNYAGNKVGVLPANAKEIAGVMFVWTNTNNEIIDENGQTLGVNI
                     DPQTFKLSGAMPATAMKKLTEAEGAKFNTANLPAAKYKIYEIHSLSTYVGEDGATLTG
                     SKAVPIEIELPLNDVVDAHVYPKNTEAKPKIDKDFKGKANPDTPRVDKDTPVNHQVGD
                     VVEYEIVTKIPALANYATANWSDRMTEGLAFNKGTVKVTVDDVALEAGDYALTEVATG
                     FDLKLTDAGLAKVNDQNAEKTVKITYSATLNDKAIVEVPESNDVTFNYGNNPDHGNTP
                     KPNKPNENGDLTLTKTWVDATGAPIPAGAEATFDLVNAQTGKVVQTVTLTTDKNTVTV
                     NGLDKNTEYKFVERSIKGYSADYQEITTAGEIAVKNWKDENPKPLDPTEPKVVTYGKK
                     FVKVNDKDNRLAGAEFVIANADNAGQYLARKADKVSQEEKQLVVTTKDALDRAVAAYN
                     ALTAQQQTQQEKEKVDKAQAAYNAAVIAANNAFEWVADKDNENVVKLVSDAQGRFEIT
                     GLLAGTYYLEETKQPAGYALLTSRQKFEVTATSYSATGQGIEYTAGSGKDDATKVVNK
                     KITIPQTGGIGTIIFAVAGAAIMGIAVYAYVKNNKDEDQLA"
     gene            complement(6477..9137)
                     /gene="rrgA"
                     /locus_tag="VU534_000934"
     CDS             complement(6477..9137)
                     /gene="rrgA"
                     /locus_tag="VU534_000934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PI-1 pilus tip adhesin RrgA"
                     /protein_id="HEU1513544.1"
                     /translation="MKKVRKIFQKAVAGLCCISQLTAFSSIVALAETPETSPAIGKVV
                     IKETGEGGALLGDAVFELKNNTDGTTVSQRTEAQTGEAIFSNIKPGTYTLTEAQPPVG
                     YKPSTKQWTVEVEKNGRTTVQGEQVENREEALSDQYPQTGTYPDVQTPYQIIKVDGSE
                     KNGQHKALNPNPYERVIPEGTLSKRIYQVNNLDDNQYGIELTVSGKTVYEQKDKSVPL
                     DVVILLDNSNSMSNIRNKNARRAERAGEATRSLIDKITSDSENRVALVTYASTIFDGT
                     EFTVEKGVADKNGKRLNDSLFWNYDQTSFTTNTKDYSYLKLTNDKNDIVELKNKVPTE
                     AEDHDGNRLMYQFGATFTQKALMKADEILTQQARQNSQKVIFHITDGVPTMSYPINFN
                     HATFAPSYQNQLNAFFSKSPNKDGILLSDFITQATSGEHTIVRGDGQSYQMFTDKTVY
                     EKGAPAAFPVKPEKYSEMKAAGYAVIGDPINGGYIWLNWRESILAYPFNSNTAKITNH
                     GDPTRWYYNGNIAPDGYDVFTVGIGINGDPGTDEATATSFMQSISSKPENYTNVTDTT
                     KILEQLNRYFHTIVTEKKSIENGTITDPMGELIDLQLGTDGRFDPADYTLTANDGSRL
                     ENGQAVGGPQNDGGLLKNAKVLYDTTEKRIRVTGLYLGTDEKVTLTYNVRLNDEFVSN
                     KFYDTNGRTTLHPKEVEQNTVRDFPIPKIRDVRKYPEITISKEKKLGDIEFIKVNKND
                     KKPLRGAVFSLQKQHPDYPDIYGAIDQNGTYQNVRTGEDGKLTFKNLSDGKYRLFENS
                     EPAGYKPVQNKPIVAFQIVNGEVRDVTSIVPQDIPAGYEFTNDKHYITNEPIPPKREY
                     PRTGGIGMLPFYLIGCMMMGGVLLYTRKHP"
     gene            9653..11182
                     /gene="rlrA"
                     /locus_tag="VU534_000935"
     CDS             9653..11182
                     /gene="rlrA"
                     /locus_tag="VU534_000935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000933118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PI-1 pilus transcriptional regulator RlrA"
                     /protein_id="HEU1513545.1"
                     /translation="MLNKYIEKRITDKITILNILLDIRSIELDELSTLTSLQSKSLLS
                     ILQELQETFEEELTFNLDTQQVQLIEHHSHQTNYYFHQLYNQSTILKILRFFLLQGNQ
                     SFNEFTQKEYISIATGYRVRQKCGLLLRSVGLDLVKNQVVGPEYRIRFLIALLQFHFG
                     IEIYDLNDGSMDWVTHMIVQSNSQLSHELLEITPDEYVHFSILVALTWKRREFPLEFP
                     ESKEFEKLKNLFMYPILMEHCQTYLEPHANMTFTQEELDYIFLVYCSANSSFSKDKWN
                     QEKKTHTIQLILQHTRGKHLLSKFKNILGNDISNSLSFLTALTFLTRTFLFGLQNLVP
                     YYNYYEHYGIESDKPLYHISKAIVQEWMTEQKIEGVIDQHRLYLFSLYLTETIFSSLP
                     AIPIFIILNNQADVNLIKSIILRNFTDKVASVTGYNILISPPPSEEHLTEPLIIITTK
                     EYLPYVKKQYPKGKHHFLTIALDLHVSQQRLIYQTIVDIRKEAFDKRVAMIAKKAHYL
                     L"
     gene            11447..12709
                     /locus_tag="VU534_000936"
     CDS             11447..12709
                     /locus_tag="VU534_000936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HEU1513546.1"
                     /translation="MEHINHTTLLIGIKDKNITLNKAIQHDTHIEVFATLDYHPPKCK
                     HCKGKQIKYDFQKPSKIPFIEIGGFPSLIHLKKRRFQCKSCRKVTVAETTLVQKNCQI
                     SEMVRQKIAQLLLNREALTHIASKLAISTSTSTVYRKLKQFHFQEDYTTLPEILSWDE
                     FSYQKGKLAFIAQDFNTKKIMTILDNRRQTTIRNHFFKYSKEARKKVKVVTVDMSGSY
                     IPLIKKLFPNAKIVLDRFHIVQHMSRALNQTRINIMKQFDDKSLEYRALKYYWKFILK
                     DSRKLSLKPFYARTFRETLTPRECLKKIFTLVPELKDYYDLYQLLLFHLQEKNTDQFW
                     GLIQDTLPHLNRTFKTTLSTFICYKNYITNAIELPYSNAKLEATNKLIKDIKRNAFGF
                     RNFENFKKRIFIALNIKKERTKFVLSQA"
     gene            complement(12847..15171)
                     /gene="pflB"
                     /locus_tag="VU534_000937"
     CDS             complement(12847..15171)
                     /gene="pflB"
                     /locus_tag="VU534_000937"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HEU1513547.1"
                     /translation="MVVKTVVEAQDIFDKAWEGFKGVDWKEKASVSRFVQANYTPYDG
                     DESFLAGPTERSLHIKKIVEETKAHYEETRFPMDTRPTSIADIPAGFIDKENEVIFGI
                     QNDELFKLNFMPKGGIRMAETTLKENGYEPDPAVHEIFTKYVTTVNDGIFRAYTSNIR
                     RARHAHTVTGLPDAYSRGRIIGVYARLALYGADYLMQEKVNDWNAIKEIDEETIRLRE
                     EVNLQYQALQQVVRLGDLYGVDVRKPAMNVKEAIQWVNIAFMAVCRVINGAATSLGRV
                     PIVLDIFAERDLARGTFTESEIQEFVDDFVMKLRTVKFARTKAYDQLYSGDPTFITTS
                     MAGMGNDGRHRVTKMDYRFLNTLDNIGNSPEPNLTVLWTDKLPYNFRRYCMHMSHKHS
                     SIQYEGVTTMAKDGYGEMSCISCCVSPLDPENEEQRHNIQYFGARVNVLKALLTGLNG
                     GYDDVHKDYKVFDIEPIRDEVLEFESVKANFEKSLDWLTDTYVDALNIIHYMTDRYNY
                     EAVQMAFLPTKQRANMGFGICGFANTVDTLSAIKYATVKPIRDEDGYIYDYETIGDYP
                     RWGEDDPRSNELAEWLIEAYTTRLRSHKLYKDAEATVSLLTITSNVAYSKQTGNSPVH
                     KGVYLNEDGSVNLSKLEFFSPGANPSNKAKGGWLQNLNSLSSLDFSYAADGISLTTQV
                     SPRALGKTRDEQVDNLVTILDGYFENGGQHVNLNVMDLNDVYEKIMSGEDVIVRISGY
                     CVNTKYLTPEQKTELTQRVFHEVLSMDDALDALS"
     gene            15519..16580
                     /gene="dinB"
                     /locus_tag="VU534_000938"
     CDS             15519..16580
                     /gene="dinB"
                     /locus_tag="VU534_000938"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000904550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HEU1513548.1"
                     /translation="MLIFPLLNDLSRKIIHIDMDAFFAAVEIRDNPKLRGKPVIIGSD
                     PRQTGGRGVVSTCSYEARAFGVHSAMSSKEAYERCPQAVFISGNYEKYKSVGLQIRAI
                     FKRYTDLIEPMSIDEAYLDVTENKLGIKSAVKIARLIQKDIWQELHLTASAGVSYNKF
                     LAKMASDYQKPHGLTVILPEQAEDFLKQMDISKFHGVGKKTVERLHQMGVFTGADLLE
                     VPEVTLIDRFGRLGYDLYRKARGIHNSPVKSNRIRKSIGKEKTYGKILLAEEDIKKEL
                     TLLSEKVALNLHQQEKAGKIVILKIRYEDFSTLTKRKSLAQKTQDASQISQIALQLYE
                     ELSKKERGVRLLGITMTGF"
     gene            complement(16727..17572)
                     /locus_tag="VU534_000939"
     CDS             complement(16727..17572)
                     /locus_tag="VU534_000939"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000273482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HEU1513549.1"
                     /translation="MYLIEILKSIFFGIVEGITEWLPISSTGHLILAEEFIQYQNQNE
                     AFMSMFNVVIQLGAILAVMVIYFNKLNPFKPTKDKQEVRKTWRLWLKVLIATLPLLGV
                     FKFDDWFDTHFHNMVSVALMLIIYGVAFIYLEKRNKARAIEPSVTELDKLPYTTAFYI
                     GLFQVLALLPGTSRSGATIVGGLLNGTSRSVVTEFTFYLGIPVMFGASALKIFKFVKA
                     GELLSFGQLFLLLVAMGVAFAVSMVAIRFLTSYVKKHDFTLFGKYRIVLGSVLLLYSF
                     VRLFV"
     gene            complement(17603..17740)
                     /locus_tag="VU534_000940"
     CDS             complement(17603..17740)
                     /locus_tag="VU534_000940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001270407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1513550.1"
                     /translation="MRYQTHYQLKQKLWLEPFGNRQAIGGNELIHSGLFQVYHLGFGS
                     S"
     gene            17827..18844
                     /locus_tag="VU534_000941"
                     /pseudo
     CDS             17827..18844
                     /locus_tag="VU534_000941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841243.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            complement(19145..21034)
                     /locus_tag="VU534_000942"
     CDS             complement(19145..21034)
                     /locus_tag="VU534_000942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2207 domain-containing protein"
                     /protein_id="HEU1513551.1"
                     /translation="MKKTFFLLVLGLFCLLPLSVFAIDFKINSYQGDLYIHADNTAEF
                     RQKIVYQFEEDFKGQIVGLGRAGKMPSGFDIDPHPKIQAAKNGAELADVTSEVTEEAD
                     GYTVRVYNPGQEGDIVEVDLVWNLKNLLFLYDDIAELNWQPLTDSSESIEKFEFHVRG
                     DKGAEKLFFHTGKLFREGTIEKSNLDYTIRLDNLPAKRGVELHAYWPRTDFASARDQG
                     LKGNRLEEFNKIEDSIVREKDQSKQLVTWVLPSILSISLLLSVCFYFIYRRKTTPSVK
                     YAKNHRLYEPPMELEPMVLSEAVYSTSLEEVSPLVKGAGKFTFDQLIQATLLDVIDRG
                     NVSIISEGDAVGLRLVKEDGLSSFEKDCLNLAFSGKKEETLSNLFADYKVSDSLYRRA
                     KVSDEKRIQARGLQLKSSFEEVLNQMQEGVRKRVSFWGLPDYYRPLTGGEKALQVGMG
                     ALTILPLFIGFGLFLYSLDVHGYLYLPLPILGFLGLVLSVFYYWKLRLDNRDGVLNEA
                     GAEVYYLWTSFENMLREIARLDQAELESIVVWNRLLVYATLFGYADKVSHLMKVHQIQ
                     VENPDINLYVAYGWHSTFYHSTAQMSHYASVANTASTYSVSSGSGSSGGGFSGGGGGG
                     SIGAF"
     gene            21172..22737
                     /locus_tag="VU534_000943"
     CDS             21172..22737
                     /locus_tag="VU534_000943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HEU1513552.1"
                     /translation="MRKIYLSIFTSLLLMLGLVNVAQADEYLRIGMEAAYAPFNWTQD
                     DDSNGAVKIDGTNQYANGYDVQIAKKIAKDLGKEPLVVKTKWEGLVPALTSGKIDMII
                     AGMSPTAERKQEIAFSSSYYTSEPVLLVKKDSAYASAKSLDDFNGAKITSQQGVYLYN
                     LIAQIPGAKKETAMGDFAQMRQALEAGVIDAYVSERPEALTAEAANSKFKMIQVEPGF
                     KTGEEDTAIAIGLRKNDNRISQINASIETISKDDQVALMDRMIKEQPAEATTTEETSS
                     SFFSQVAKILSENWQQLLRGAGITLLISIVGTIIGLIIGLAIGVFRTAPLSENKVIYG
                     LQKLVGWVLNVYIEIFRGTPMIVQSMVIYYGTAQAFGINLDRTLAAIFIVSINTGAYM
                     TEIVRGGILAVDKGQFEAATALGMTHNQTMRKIVLPQVVRNILPATGNEFVINIKDTS
                     VLNVISVVELYFSGNTVATQTYQYFQTFTIIAVIYFVLTFTVTRILRFIERRMDMDTY
                     TTGANQMQTEDLK"
     gene            22737..23477
                     /locus_tag="VU534_000944"
     CDS             22737..23477
                     /locus_tag="VU534_000944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEU1513553.1"
                     /translation="MTQAILEIKHLKKSYGQNEVLKDISLTVHKGEVISIIGSSGSGK
                     STFLRSINLLETPTDGQILYHGQNVLEKGYDLTQYREKLGMVFQSFNLFENLNVLENT
                     IVAQTTVLKRERTEAEKIAKENLEKVGMGERYWQAKPKQLSGGQKQRVAIARALSMNP
                     DAILFDEPTSALDPEMVGEVLKIMQDLAQEGLTMIVVTHEMEFARDVSHRVIFMDKGV
                     IAEEGKPEDLFTNPKEDRTKEFLQRYLK"
     gene            complement(23586..23801)
                     /locus_tag="VU534_000945"
     CDS             complement(23586..23801)
                     /locus_tag="VU534_000945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1513554.1"
                     /translation="MAKSNFEKVESVVGWVRDKKITGYRISKETNAREMSIIALAQGR
                     AKVKNISFETALGLIDFYEKNYEKFED"
     gene            complement(24536..25786)
                     /gene="ilvA"
                     /locus_tag="VU534_000946"
     CDS             complement(24536..25786)
                     /gene="ilvA"
                     /locus_tag="VU534_000946"
                     /EC_number="4.3.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine ammonia-lyase IlvA"
                     /protein_id="HEU1513555.1"
                     /translation="MLSSKDIIKAHKVLNGVVVNTPLDYDHYLSEKYGAKIYLKKENA
                     QRVRSFKIRGAYYAISQLSKEERERGVVCASAGNHAQGVAYTCNEMKIPATIFMPITT
                     PQQKIGQVRFFGGDFVTIKLVGDTFDASAKAAQEFTVSENRTFIDPFDDAHVQAGQGT
                     VAYEILEEARKESIDFDAVLVPVGGGGLIAGVSTYIKETSPEIEVIGVEANGARSMKA
                     AFEAGGPVKLKEIDKFADGIAVQKVGQLTYEATRQHIKTLVGVDEGLISETLIDLYSK
                     QGIVAEPAGAASIASLEVLAEYIKGKTICCIISGGNNDINRMPEMEERALIYDGIKHY
                     FVVNFPQRPGALREFVNDILGPNDDITRFEYIKRASKGTGPVLIGIALADKHDYAGLI
                     RRMEGFDPAYINLNGNETLYNMLV"
     gene            complement(25836..26192)
                     /locus_tag="VU534_000947"
     CDS             complement(25836..26192)
                     /locus_tag="VU534_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001027901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HEU1513556.1"
                     /translation="MNITNLFSIKTGCDETDRQLQKLFFQLDLQLGELTDQLRKLDSN
                     FVPRSQFVDTLDLNDVEYKEILNYFIFHRNDSEESLVEWLYDWISTNRYELPKEFSIR
                     MAHKYHESVTEVFGDE"
     gene            complement(26430..26666)
                     /locus_tag="VU534_000948"
     CDS             complement(26430..26666)
                     /locus_tag="VU534_000948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1513557.1"
                     /translation="MLADQNKADWSYDENAVINIYDDANFEDGRLHMNFEQFFKLAQI
                     AREEGLEIHSPFERAGATKSARYIAKWILRNKKH"
     gene            complement(26773..27795)
                     /gene="ilvC"
                     /locus_tag="VU534_000949"
     CDS             complement(26773..27795)
                     /gene="ilvC"
                     /locus_tag="VU534_000949"
                     /EC_number="1.1.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HEU1513558.1"
                     /translation="MTVQMEYEKDVKVAALDGKKIAVIGYGSQGHAHAQNLRDSGRDV
                     IIGVRPGKSFDKAKEDGFDTYTVAEATKLADVIMILAPDEIQQELYEAEIAPNLEAGN
                     AVGFAHGFNIHFEFIKVPADVDVFMCAPKGPGHLVRRTYEEGFGVPALYAVYQDATGN
                     AKNIAMDWCKGVGAARVGLLETTYKEETEEDLFGEQAVLCGGLTALIEAGFEVLTEAG
                     YAPELAYFEVLHEMKLIVDLIYEGGFKKMRQSISNTAEYGDYVSGPRVITEQVKENMK
                     AVLADIQNGKFANDFVNDYKAGRPKLTAYREQAANLEIEKVGAELRKAMPFVGKNDDD
                     AFKIYN"
     gene            complement(27861..28337)
                     /gene="ilvN"
                     /locus_tag="VU534_000950"
     CDS             complement(27861..28337)
                     /gene="ilvN"
                     /locus_tag="VU534_000950"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002927678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase small subunit"
                     /protein_id="HEU1513559.1"
                     /translation="MRRMLTAKLQNRSGVLNRFTGVLSRRQVNIESISVGATEDPNVS
                     RITIIIDVASHDEVEQIIKQLNRQIDVIRIRDITDKPHLEREVILVKMSAPAEKRAEI
                     LAIIQPFRATVVDVAPSSITIQMTGNAEKSEALLRVIRPYGIRNIARTGATGFTRD"
     gene            complement(28330..30030)
                     /locus_tag="VU534_000951"
     CDS             complement(28330..30030)
                     /locus_tag="VU534_000951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase large subunit"
                     /protein_id="HEU1513560.1"
                     /translation="MEKISLESPKTGSDLVLETLRDLGVDTIFGYPGGAVLPFYDAIY
                     NFKGIRHILGRHEQGCLHEAEGYAKSTGKLGVAVVTSGPGATNAITGIADAMSDSVPL
                     LVFTGQVARAGIGKDAFQEADIVGITMPITKYNYQVRETADIPRIITEAVHIATTGRP
                     GPVVIDLPKDISALETDFIYSPEVNLPSYQPTLEPNDMQIKKILKQLSKAKKPVLLAG
                     GGISYAEAATELNEFAERYQIPVVTSLLGQGTIATSHPLFLGMGGMHGSFAANIAMTE
                     ADFMISIGSRFDDRLTGNPKTFAKNAKVAHIDIDPAEIGKIISADIPVVGDAKKALQM
                     LLAEPTVHNNTEKWIEKVTKDKNRVRSYDKKERVVQPQAVIERIGELTNGDAIVVTDV
                     GQHQMWTAQYYPYQNERQLVTSGGLGTMGFGIPAAIGAKIANPDKEVVLFVGDGGFQM
                     TNQELAILNIYKVPIKVVMLNNHSLGMVRQWQESFYEGRTSESVFDTLPDFQLMAQAY
                     GIKNYKFDNPETLAQDLEVITEDVPMLIEVDISRKEQVLPMVPAGKSNHEMLGVQFHA
                     "
     gene            complement(30230..31897)
                     /locus_tag="VU534_000952"
     CDS             complement(30230..31897)
                     /locus_tag="VU534_000952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HEU1513561.1"
                     /translation="MSKITTSLFQEMVQAASTRLNKQAEYVNSLNVFPVPDGDTGTNM
                     GMTIENGAKEVADKPASTVGEVASILAKGLLMGARGNSGVITSQLFRGFSQAIKDKDE
                     LTGQDLALAFQSGVEVAYKAVMKPVEGTILTVSRGAAIGAKKKAEQTDDAVEVMRAAL
                     EGAKTALAKTPDMLPVLKEVGVVDSGGQGLVFIYEGFLSALTGEYIASEDFVATPANM
                     SEMINVEHHKSVAGHVATEDITFGYCTEIMVALKQGPTYAKDFDYDEFRNYLDELGDS
                     LLVVNDDEIVKVHVHTEDPGLVMQEGLKYGSLVKVKVDNMRNQHEAQVEKEATQVIKS
                     AEEKEYALIAVVAGKGLADIFCSQGVDYVIEGGQTMNPSTEDFIKAVEQVNARNIIFL
                     PNNKNIFMAAQSAAEVLEQPAVVVEARTLPQGMTSLLAFDPSKSIEENQERMTAALSD
                     VVSGSVTTAVRDTTIDGLEIHENDNLGMVDGKILVSNPDMHQTLTETLKHMLDEDSEI
                     VTFYVGEDGSEELANEIAQEIVEEFEDVEVEIHQGQQPVYPYLFSVE"
     gene            complement(31900..32265)
                     /locus_tag="VU534_000953"
     CDS             complement(31900..32265)
                     /locus_tag="VU534_000953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEU1513562.1"
                     /translation="MTVKINTKDGQIELTDEVIATVVGGAATEIFGVVGMASKNALKD
                     NFQALLGKENYSKGVVVKAAEDGSIAVDVYTVLSYGTKISEVSKNIQERVAFSLENQL
                     GITAQTVNVYIQNIKVVGE"
     gene            complement(32422..32610)
                     /locus_tag="VU534_000954"
     CDS             complement(32422..32610)
                     /locus_tag="VU534_000954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008536053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HEU1513563.1"
                     /translation="MAKVCYFTGRKTVSGNNRSHAMNQTKRAVKPNLQKVTVLIDGKP
                     KKVWASARALKSGKVERV"
     gene            complement(32726..32902)
                     /locus_tag="VU534_000955"
     CDS             complement(32726..32902)
                     /locus_tag="VU534_000955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 8"
                     /protein_id="HEU1513564.1"
                     /translation="MDSDIVVRKSIDELWDLDLTAIPLAAVRDDFYTHNFNSGVLLIN
                     DGMWRAENVTQDLI"
     gene            complement(33013..33210)
                     /locus_tag="VU534_000956"
     CDS             complement(33013..33210)
                     /locus_tag="VU534_000956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 8"
                     /protein_id="HEU1513565.1"
                     /translation="MKEEKKAIVLGADNAYMDKVETTIKSLCVHHYNLKFYVFNDDLP
                     REWFQLMEKRLETLNSEIVNV"
     gene            complement(33493..35037)
                     /locus_tag="VU534_000957"
     CDS             complement(33493..35037)
                     /locus_tag="VU534_000957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HEU1513566.1"
                     /translation="MNIQEEIKKRRTFAIISHPDAGKTTITEQLLYFGGEIREAGTVK
                     GKKTGTFAKSDWMDIEKQRGISVTSSVMQFDYDGKRVNILDTPGHEDFSEDTYRTLMA
                     VDAAVMVVDSAKGIEAQTKKLFEVVKHRGIPVFTFMNKLDRDGREPLDLLQELEEILG
                     IASYPMNWPIGMGKAFEGLYDLYNQRLELYKGDERFASLEDGDKLFGSNPFYEQVKDD
                     IELLNEAGNEFSEEAILAGELTPVFFGSALTNFGVQTFLETFLKFAPEPHGHKKTDGE
                     IVDPYDKDFSGFVFKIQANMDPRHRDRIAFVRIVSGEFERGMSVNLPRTGKGAKLSNV
                     TQFMAESRENVTNAVAGDIIGVYDTGTYQVGDTLTVGKNKFEFEPLPTFTPEIFMKVS
                     AKNVMKQKSFHKGIEQLVQEGAVQLYKNYQTGEYMLGAVGQLQFEVFKHRMEGEYNAE
                     VVMNPMGKKTVRWIKPEDLDERMSSSRNILAKDRFDQPVFLFENDFALRWFADKYPDV
                     ELEEKM"
     gene            35250..35552
                     /gene="gatC"
                     /locus_tag="VU534_000958"
     CDS             35250..35552
                     /gene="gatC"
                     /locus_tag="VU534_000958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006147946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HEU1513567.1"
                     /translation="MKITQEEVTHVANLSKLRFSEEETAAFATTLSKIVDMVELLGEV
                     DTTGVAPTTTMADRKTVLRPDVAEEGIDRDRLFKNVPEKDNYYIKVPAILDNGGDA"
     gene            35552..37018
                     /gene="gatA"
                     /locus_tag="VU534_000959"
     CDS             35552..37018
                     /gene="gatA"
                     /locus_tag="VU534_000959"
                     /EC_number="6.3.5.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HEU1513568.1"
                     /translation="MTFNNKTIEELHNLLVSKEISATELTQATLENIKSREEALNSFV
                     TIAEEQALVQAKAIDEAGIDADNVLSGIPLAVKDNISTDGILTTAASKMLYNYEPIFD
                     ATAVANAKTKGMIVVGKTNMDEFAMGGSGETSHYGATKNAWNHSKVPGGSSSGSAAAV
                     ASGQVRLSLGSDTGGSIRQPAAFNGIVGLKPTYGTVSRFGLIAFGSSLDQIGPFAPTV
                     KENALLLNAIASEDAKDSTSAPVRIADFTSKIGQDIKGMKIALPKEYLGEGIDPEVKE
                     TILNAAKHFEKLGAIVEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGYRAEDA
                     TNLDEIYVNSRSQGFGEEVKRRIMLGTFSLSSGYYDAYYKKAGQVRTLIIQDFEKVFA
                     DYDLILGPTAPSVAYDLDSLNHDPVAMYLADLLTIPVNLAGLPGISIPAGFSQGLPVG
                     LQLIGPKYSEETIYQAAAAFEATTDYHKQQPVIFGGDN"
     gene            37018..38460
                     /gene="gatB"
                     /locus_tag="VU534_000960"
     CDS             37018..38460
                     /gene="gatB"
                     /locus_tag="VU534_000960"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HEU1513569.1"
                     /translation="MNFETVIGLEVHVELNTNSKIFSPTSAHFGNDQNANTNVIDWSF
                     PGVLPVLNKGVVDAGIKAALALNMDIHKKMHFDRKNYFYPDNPKAYQISQFDEPIGYN
                     GWIEVKLEDGTTKKIGIERAHLEEDAGKNTHGTDGYSYVDLNRQGVPLIEIVSEADMR
                     SPEEAYAYLTALKEVIQYAGISDVKMEEGSMRVDANISLRPYGQEKFGTKTELKNLNS
                     FSNVRKGLEYEVQRQAEILRSGGQIRQETRRYDEANKATILMRVKEGAADYRYFPEPD
                     LPLFEISDEWIEEMRTELPEFPKERRARYVSDLGLSDYDASQLTANKVTSDFFEKAVA
                     LGGDAKQVSNWLQGEVAQFLNAEGKTLEQIELTPENLVEMIAIIEDGTISSKIAKKVF
                     VHLAKNGGGAREYVEKAGMVQISDPAILIPIIHQVFADNEAAVADFKSGKRNADKAFT
                     GFLMKATKGQANPQVALKLLAQELAKLKEN"
     gene            38589..39149
                     /gene="efp"
                     /locus_tag="VU534_000961"
     CDS             38589..39149
                     /gene="efp"
                     /locus_tag="VU534_000961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HEU1513570.1"
                     /translation="MIEASKLKAGMTFETADGKLIRVLEASHHKPGKGNTIMRMKLRD
                     VRTGSTFDTSYRPEEKFEQAIIETVPAQYLYKMDDTAYFMNTETYDQYEIPVVNVENE
                     LLYILENSDVKIQFYGTEVIGVTVPTTVELTVAETQPSIKGATVTGSGKPATMETGLV
                     VNVPDFIEAGQKLVINTAEGTYVSRA"
     gene            39171..39560
                     /locus_tag="VU534_000962"
     CDS             39171..39560
                     /locus_tag="VU534_000962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEU1513571.1"
                     /translation="MGIEEQLGEIVIAPRVLEKIIAIATAKVEGVHSFSNRSVSDTLS
                     KLSLGRGIYLKNVDEELTADIYLYLEYGVKVPKVAVAIQKAVKDAVRNMADVELAAIN
                     IHVAGIVPDKTPKPELKDLFDEDFLND"
     gene            39553..39975
                     /gene="nusB"
                     /locus_tag="VU534_000963"
     CDS             39553..39975
                     /gene="nusB"
                     /locus_tag="VU534_000963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000203663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HEU1513572.1"
                     /translation="MTSPLLESRRQLRKCAFQALMSLEFGTDVETACRFAYTHDREDT
                     DVQLPAFLIDLVSGVQAKKEELDKQITQHLKAGWTIERLTLVERNLLRLGVFEITSFD
                     TPQLVAVNEAIELAKDFSDQKSARFINGLLSQFVTEEQ"
     gene            complement(40010..41133)
                     /locus_tag="VU534_000964"
                     /pseudo
     CDS             complement(40010..41133)
                     /locus_tag="VU534_000964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT        12173 a         9152 c         7375 g        12433 t
ORIGIN      
        1 tttttcaacc cactacagtt gacaaagagc cggaaaaagg aacagcctta gctttccttt
       61 catttctttt tatttccctc gtagtaaacg tgctagcttc cacaaaacaa acaggattcc
      121 cagaaatgcc agtaccacta gcccacggta caaccattga gaggttgcaa cacgcgatac
      181 agattgtcct tctttcgtaa aagcaaccct cgcaactgca gctgtttgtg gatctgattt
      241 ttgataaaca gcgactcgtt caaaattcac taataagcgt ttattaaagg taggaatcgg
      301 atcgcaggtt atcaaggtca tgatattttt agagctaacc gattctaatt tttcccattc
      361 cgacggtaaa ataatctctg tgtccatcat ctgatattct acaatttcct ggccattatc
      421 ataataaaga gcatctccaa cttttagctg atccaaatgg cggaaaaaga catggcttgg
      481 ctctgcacgg tgcccagcaa tcactgagcg aatccctgta ccatccagag gcagcggtgt
      541 accatccaca tgagccaagc ccatccctaa atgatgataa tctgctccca aataaaccgg
      601 ctccatgatt tccaaacttg gaatagacaa gtaaccatag actgcatcag ggtcgtcaga
      661 cacttggtaa ttgacctcat atccctccgc caaaaaagga tctacaatgc gattttgcga
      721 agccaagcgt tgattgtagg cgagagaatg gttctgttgt tcttggtaca tttcagttgt
      781 catggatttc acaaatgtag catgaccttt cacctgtcca agagactgca acaccatctg
      841 tccaaaacaa taaataggaa tcaaacaggc taccaacatc aacaagtatc ccaataaggc
      901 tcgtagttta gtccttgaca tgacgcccct ccaattgctt ttctagtcct ttgacaatcc
      961 gtcgattacg atacacgcga tacagcaaga gaaggatgac cgccatcgct cctagtaata
     1021 accacaacca gaattgccca cgctctctca ccgctcgatt ccgctctgca attggtgccg
     1081 tatacggaat ccgcttccca cgtaccaaca gacgatgact gttaatcata tacggtgtac
     1141 aagtcaacaa ggtcgcataa tcttccccat gttgaatcaa gacaggctca aagtcattcg
     1201 gctccaccgt cactatctga tccacttggt aggccaacac ctgatctaaa acgtgaagat
     1261 aaaagatatc cccttttttc atcttatcca attgactgaa caattctgcc gttggcaatc
     1321 ctctgtgagc agtgatcact gtatgggtat tttcacctcc aacaggcagc gaagcccctt
     1381 ctaacagccc tgcccctttc tgaagaatgt cctcactcgt tccgacatac atcggaattt
     1441 cctgatcaat cgcaggaatt tccacatagc caatccgctc atggaccttt agcatattgg
     1501 catattctga gacgcctttc tttttctctt gctctgtaaa aggatcaaga atttcagatg
     1561 gtttcaaggt cgcattgaag gcttgagcca agcgccaacg ctcctcaagt tctgccttat
     1621 ccatctggga aaccgtctca tcaaactctt taataacctc gtttgactca atacgataat
     1681 aataacgaga caccaatgga tatatcgcaa cggcgaatcc tactaagaaa atcagaagaa
     1741 ggatcagcgg atgtttcttc ttttttgtgc ctttttttcg tgaacgtcta ctgttgtcca
     1801 tcctccacct tcacttcctt ccttgctgct ttcagcgcct tcaaagcctt ttccggttgt
     1861 tttttcttct tgcgcaagcg tcgaataatc cataaaagaa tcacaatcaa accaactgcc
     1921 acataaaaca ggtagcgata gagatgactg agtttgtttg ctgcaataaa ttcttcctca
     1981 acctctgcta cgtacggtat ccgatgcccc cgaaccaata gacgatgggt attgatcatg
     2041 tatggcgtac aagtcagcaa ggtcacataa tcatgacctg gtacaatcaa taaatcatca
     2101 aagttcgtcg gctcaatcac ctttacttga tccacttgat aggccatcac ttccttgata
     2161 ttgtgcacat aaaacttatc cccaacttta agtttggtca aatccgtaaa catcttagct
     2221 gttggcaaac ctgtatgtgc cgtaatcacc gcatgggtcg aattgcctcc gatcggcaga
     2281 gaagttccct ctagatgccc agccccttgc tgcaatacct cttcagcagt accagcataa
     2341 accggcaaat ccacgtcaat aacggggatt tccacatgcc ccatccgctc atggatttct
     2401 aacatacgtg catactctgc tcgccctttt ttcttcattt cttccgacca aggatcgcca
     2461 ctcactacat tattcaaaga gtcattgaag gcttgtgcca atttcattcg ttcatcaatg
     2521 tcagcctcat ccaacgttgc tttttcctta tcaaagtcag caatttgttg atttgattcc
     2581 actcgataat acaagcgaga caccagcgga tacgccatta ccgccattcc aatgaaaaat
     2641 accactccta ataggagatt atttcgtttt tgcttttttg tttttaccat ttttatcagc
     2701 atccctttat cttcaaactc atcattttat cgcttttcct aacagacaat cctatctgct
     2761 aagagaaacg agaaaatctc atttctttct gattcaccat ccattttaaa tcagaatccc
     2821 agtcctgtcc attcctaaaa tgattaccag accagtccta tcgttttaca aacaataacc
     2881 cacaatgagg ctggcacaat ctgcccagcc tcatatccgt tattgtgatt catgccacat
     2941 caccatgatt cctgattaac atcacctcag agtactctgg tcttcccttc agcctgctat
     3001 ctttttcata atgatgtaca ttgaatatca gttatttggt tttttcgtaa gataataacc
     3061 actaccaaac aacaaaatgg caacaagcat caagatatac aaggtttctt cccctgtatc
     3121 tggcacatca atccgtggtc gcttgttatt tttaaccact gttaccagtt ccttacgagt
     3181 atctttcccg attgtaaagg aaacaggcga tgttaattga acataaccag ttggagcttg
     3241 gagctcccat aaatagtatg tcccatactc tagaccttcc actcggaaac gaccatcttt
     3301 ccctgatgtt acaactactt ccttaccatt ttgaagaaca ggagtatagt gtccgctttc
     3361 ttctttcatg actttgaaca ttgccccttg aagagaggta ttggtccgac catccacctt
     3421 cataaagtca acattgccac gtggtaattt ctgattgaca accgtaatcg tcaccagctg
     3481 atgatctacc agctggacat ccgtatccag cgtcgtaaca gcatagcctg ccagtggctc
     3541 cacctccttg aaacgatagt tcccaagagg aagatttgtc acaaaaatct ctccattttt
     3601 atcagtatag agagttctcc ctacttgacc agaagaactg taacggtatt ctccaatcaa
     3661 gggaacctct ttttcagaaa catctcttgc tactgatacc aatttaaagc cgacaccctc
     3721 caagcgattg tggtcttgat ccacctttat cagcttcacc tttgttgtca ttgtatctgt
     3781 ttttttcgct acaatgacca aaggctctac cgtttgatct gtcatttcaa aaagaaattc
     3841 agctggataa gaaaccgcat ccgtctggat aatagagcga acatagtaaa gaccatttgg
     3901 aatatgagat acttcaatct gattctcaag gaaggtcatc tcaaacgaag tctttttgaa
     3961 agaagaaagt ttattctcat cccacgaatg caagtctctt acaatttgca cccgatcatc
     4021 ataggaatac gaatcatcca acttccatac ttgcaaccga tgaccatcac gagatggcaa
     4081 ttgactaacc acctcctgat agttctccaa ttgcaagacc aacgtgtgat cttcttgcgc
     4141 ttggactgca tgtgcacccc atacaagaga aaaacacaga gccataacaa agaagatacg
     4201 actaatcatt ttctgcattt tctgcattgt catcaatggc tcctttctct cttacttaag
     4261 caagttgatc ctcatctttg ttgtttttaa catatgcgta cactgcaata cccataatcg
     4321 cagcccccgc tacagcaaag ataattgtac caataccacc cgtttgtggg atagtgattt
     4381 ttttgttgac tacttttgta gcgtcatctt tacctgaacc agcagtatac tcaatgcctt
     4441 gtccagtcgc tgaataagaa gttgcagtga cttcaaattt ctgacggcta gttagtaatg
     4501 cataaccagc aggctgtttt gtttcttcta agtaatatgt acctgcaaga aggcctgtaa
     4561 tttcaaagcg accttgtgca tcagaaacta atttcacaac attttcattg tccttatctg
     4621 ccacccattc aaatgcattg ttggcagcaa tcacagcagc attataagca gcttgagctt
     4681 tgtcaacttt ctctttttct tgctgagttt gttgttgtgc agtaagagcg ttataagcag
     4741 caactgctct atctaaagca tcctttgttg taacaaccaa ctgcttctct tcttgactca
     4801 ctttatctgc tttacgtgct aaatattgac cagcattatc agcatttgca attacaaatt
     4861 ctgccccagc taaacgatta tctttatcat taactttgac aaacttttta ccatatgtaa
     4921 caacttttgg ctctgttgga tcaagtggtt ttggattttc gtctttccag ttcttgacag
     4981 caatttctcc agctgtagtg atttcttgat aatctgctga ataccctttt atactacgtt
     5041 caacgaattt atattctgta tttttatcca atccgttaac agtaactgta tttttgtctg
     5101 ttgtcaaagt tacagtttgt acaactttac cagtctgagc attaaccaaa tcgaacgttg
     5161 cttcagctcc agccggaatt ggtgcacctg tagcatcaac ccatgtcttg gtcaatgtca
     5221 aatcgccgtt ttcatttggc ttattcggct ttggagtatt cccgtgatct ggattattac
     5281 catagttaaa tgttacatca ttagattctg gtacttctac aattgctttg tcattcaatg
     5341 ttgccgaata agtgattttc acagtttttt cagcgttttg gtcattcact ttagctaaac
     5401 cagcatctgt taatttcaaa tcaaaaccag ttgctacttc tgttagagca taatcacctg
     5461 cttcaagtgc aacatcatca acagttactt tcactgtacc tttgttgaat gccaaacctt
     5521 cagtcattct atcgctccag tttgctgttg cataattagc aagtgctgga atttttgtaa
     5581 caatttcgta ctctacaaca tctccaactt ggtggttcac aggtgtatct ttatctacac
     5641 gtggtgtatc tggatttgct ttacctttga aatctttatc aatttttggc tttgcttctg
     5701 tattttttgg atacacatgc gcatccacaa catcgttcaa tggtaattca atttcaattg
     5761 gaactgcttt agaacctgtt aaggttgctc catcttcacc gacataagtt gataaactgt
     5821 gaatttcata aattttatac ttagcagctg gtaaatttgc cgtgttaaat ttagctcctt
     5881 cagcttctgt taattttttc attgcagttg ccggcattgc ccctgagagt ttaaatgttt
     5941 gtggatcaat attcactcct agagtttggc cattttcatc aataatttca ttattagtat
     6001 ttgtccaaac gaacataaca ccggcaattt cttttgcatt tgcaggtaga acacccactt
     6061 tattaccagc atagttacct gtttctaact catttgcaat tttatccata tccccatctg
     6121 ttgccaatag tttatgaacg gtaacagatg ttgttgtcgt cccagccgca aaaactgttg
     6181 cagctgaaaa caggctactc gctgtcagta ataaggcagc aagcattgtt aaaaatttgt
     6241 tgattgattt catgatttct ccttattcat atctcttaaa atcaactgtg agcaatgtaa
     6301 tgaattacac atgacaataa taatcctttt tctgtgcaag ttttcgaaaa catctcccct
     6361 ttcaatgata gtttacttac gaataaaaca ggtttcacca agtaaactta aatctcttct
     6421 tgagtgctac ttcttaaaag tatcgttcag aacatagata ttatcatttc tacactttac
     6481 ggatgtttcc gtgtgtataa tagaactcct cccatcatca tgcaacctat cagatagaat
     6541 ggcaacattc cgataccacc agttcgagga tattctctct ttggaggaat aggttcattg
     6601 gtaatatagt gcttatcatt cgtaaactcg taacccgctg gtatatcttg tggaacgatt
     6661 gaagtcacat ctctgacttc tccatttact atttggaagg caacgatagg cttattttga
     6721 acgggtttat aaccagctgg ttcagaattt tcaaataatc gatatttccc atctgacaga
     6781 tttttaaagg tcaacttacc atcttcacct gttctcacat tttgataagt gccattttga
     6841 tcaatagctc cataaatatc tggataatcc ggatgttgtt tttgaagact aaagaccgca
     6901 cctctcagtg gttttttatc atttttattg accttaataa actcaatgtc accaagtttt
     6961 ttctcttttg aaattgtgat ttctggatac ttccgcacat cacgaatctt aggaatcggg
     7021 aagtcgcgca ctgtgttctg ttctacttcc ttaggatgta aggttgttcg accattggta
     7081 tcataaaatt tattgcttac aaactcatca ttcaaacgaa cattgtaggt caacgtaact
     7141 ttttcatccg ttccaaggta cagacctgtt acacgaatcc ttttctcagt cgtatcatag
     7201 agcacttttg cattttttaa caaaccacca tcattttgtg gaccacctac agcttgtcca
     7261 ttctccaagc gactaccatc gtttgcagtt aaagtgtaat ctgctggatc aaatcttcca
     7321 tctgtgccca attgcaaatc aattaactca cccatcggat ctgtaatcgt accattctca
     7381 attgatttct tttcagttac gatggtgtgg aaataacgat tcaactgttc caatattttt
     7441 gtcgtgtcag taacattggt atagttttca ggtttactag aaatactttg cataaaacta
     7501 gtagccgttg cttcatccgt accaggatct ccgttaatac caatacctac cgtaaagaca
     7561 tcatacccat caggagcaat attcccgtta tagtaccatc ttgtagggtc accatgattg
     7621 gtaattttag cagtattaga attaaacgga taagccagaa tactctctct ccaattaagc
     7681 caaatatatc caccattaat tggatcgcct ataactgcat aaccagccgc cttcatttca
     7741 gaatattttt caggtttaac tgggaaagct gcaggagcac ctttttcata aactgtctta
     7801 tctgtaaaca tctggtaact ttgcccatct ccgcgtacaa ttgtatgttc tccactagtt
     7861 gcttgcgtaa taaaatcact taatagtatt ccatctttat taggagattt actaaaaaat
     7921 gcatttagtt gattttgata tgatggagca aacgtagcat gattaaaatt aatcggatac
     7981 gacatagttg ggacaccatc cgtaatatgg aaaatgactt tttgactatt ttgtctcgct
     8041 tgttgtgtca aaatctcatc tgccttcatc aaagctttct gagtaaaagt ggcaccgaat
     8101 tggtacatca atctatttcc atcatggtct tctgcctcgg taggtacctt attttttaat
     8161 tctacaatgt cattcttatc attagtcagc tttaaataac tataatcttt ggtattggtt
     8221 gtaaaactcg tctgatcata attccaaaaa agagaatcat tcaatcgctt tccgttttta
     8281 tctgctaccc ctttttctac tgtaaactcg gtcccatcaa agatagtgga agcataagtc
     8341 acaagcgcta ccctattttc tgaatcagat gtaattttat caataagaga acgtgtcgcc
     8401 tcaccagctc tttccgcacg tcgagcattc ttgtttcgaa tgttactcat actatttgag
     8461 ttatcgagca agataacgac atccagcggc acagacttat ctttttgttc atacactgtt
     8521 ttcccactaa ccgtcaattc gattccatat tggttatcat ccaaattatt cacttgataa
     8581 attctctttg aaagtgtacc ttctggaatc acacgttcat atggattcgg attcaacgcc
     8641 ttgtgctgtc cgtttttttc cgaaccatct accttaataa tctgataagg tgtttgaaca
     8701 tctggataag tccctgtttg tggatactgg tcagatagag cctcttctcg attttctacc
     8761 tgttcacctt ggacagtcgt ccgaccattc ttctcaactt caacagtcca ttgtttagta
     8821 gagggtttat aaccaactgg aggttgggct tctgtcaagg tgtatgtccc aggttttatg
     8881 tttgaaaata tcgcttctcc tgtttgcgcc tctgtccttt gcgaaacagt tgtgccatcc
     8941 gtattgtttt tcaactcaaa gacggcatct cctagaagcg ctcctccttc gcctgtctcc
     9001 ttaatcacta cttttcctat cgctggactg gtttcaggcg tttctgctaa agcaactatc
     9061 gaagaaaaag ctgtcaactg agatatacag cacagtcctg caactgcctt ctgaaatatc
     9121 tttcttactt ttttcatgtg tgtctccctg ttaagcatta ttcatagaac aagttaatcc
     9181 ttctatgatt cataggtact ttcaatctgt atacacgaag aaacggatta cttatgttct
     9241 gataaaattt atctcactga gttaatccgt tcactaacaa acgtagcaaa agcgtataaa
     9301 agtgcgttat agctatcttc tcaacctggc aatgacacac ttgtatacaa tatagtatag
     9361 tatagtatta ctattaacta tcctagtata aattaaaaca acttccatca caatagatat
     9421 ttttatcaca tattttttta tagaacgaca atatttgata aaaaaatatt ttctaataaa
     9481 aaaaataagc cataaaactc caccaatact cattactatc tttaaaatgc cttttattac
     9541 atgctgtttt atcaataaag tcggaaattc cacaaccttt ttgacaagac aattagtttc
     9601 ttttgtatta taataattaa aattatctat atgcaactaa gattcggtaa ctatgctaaa
     9661 caaatacatt gaaaaaagaa ttacagataa aattaccatt ttaaatatat tattggatat
     9721 tcggtctatt gaactagatg aactgtctac tttaacttca ttacaatcta aaagtctcct
     9781 aagcattttg caggaattac aagaaacatt cgaggaagag ttgacattta atttagatac
     9841 gcaacaagtt caattaatcg aacaccattc tcatcaaacg aattattact tccatcagct
     9901 ttataaccaa tcaactattt taaaaatact ccgcttcttt ctactacaag gtaatcaaag
     9961 ctttaacgaa tttacacaaa aagagtatat ttccatcgca acaggctacc gcgtacgaca
    10021 aaagtgtggc ttgttactac gttcagtagg tttggacctt gtgaaaaatc aagtagttgg
    10081 tcctgaatat cgcattcgtt ttttaattgc actcctccag tttcattttg gtattgagat
    10141 ttatgatttg aatgatggaa gtatggattg ggtcacacat atgattgtgc agtctaattc
    10201 tcaactcagt catgaactgt tagaaatcac acctgacgag tatgttcatt ttagcatact
    10261 agtggcactc acttggaaac gtcgggaatt tccacttgag ttccctgagt ccaaagagtt
    10321 tgaaaaatta aaaaacctct ttatgtatcc gattttgatg gaacattgcc aaacttactt
    10381 agagccacat gccaacatga cttttactca ggaagaactg gattatatct ttttggttta
    10441 ttgttctgct aattcttcgt tttccaagga caaatggaat caagaaaaaa agactcatac
    10501 tattcaactg attcttcagc atacaagagg aaagcatcta ctatccaagt tcaagaatat
    10561 cttaggaaat gacatttcga attctctttc ttttttaaca gcactgactt tcttaacaag
    10621 aacgtttttg tttggtttac aaaatctagt tccctattat aattattacg aacattatgg
    10681 gattgaaagc gacaagccac tgtatcatat ttcgaaagca attgttcaag agtggatgac
    10741 tgagcagaag attgaaggag ttatcgacca gcatcggctg taccttttct cactctactt
    10801 gacagaaacc atcttttcct cactacctgc tatcccgatt tttatcattt taaataatca
    10861 agcagatgta aacttaataa agtccattat tttacggaat tttactgaca aagttgcctc
    10921 tgttacagga tacaatattc taattagtcc tcctccttca gaggagcatt tgacagagcc
    10981 attgattatt attacaacga aagaatacct gccttacgtt aaaaagcagt atcccaaagg
    11041 gaaacatcac tttttgacga ttgccttaga tttgcatgtt agccaacagc gtctcatcta
    11101 tcagacaatt gtagatatcc gaaaagaggc ttttgacaaa cgggtcgcaa tgattgctaa
    11161 aaaggctcac tatttgttat aagttcatcg tactgtctac acacaaaaag gggcttccta
    11221 agccatctct attcttatcc ccatatttcc cagttttggg taaatctgaa cagaaaaaca
    11281 cttctgctct ctagtttctg ctagtgaaca aaagtgtttt ttctggctct ataatttctg
    11341 tagtgggtaa atcccactgt ggagattata gggctttttg agtatcaaaa aagtcccata
    11401 agacttataa tgaaaagcgc ctaaacaact cattagaaag tatcttatgg aacacatcaa
    11461 tcataccaca ttactcatcg gaataaaaga caaaaacatc accttaaata aagccattca
    11521 gcacgatacc catatcgaag tcttcgctac acttgattat cacccaccta aatgtaaaca
    11581 ctgtaaagga aaacaaatca aatacgactt ccaaaagcct tctaaaatcc cttttatcga
    11641 gattggtggt ttccctagcc tcattcattt gaaaaagaga cgatttcaat gcaagtcctg
    11701 tcggaaagtc actgtagctg aaacaactct cgttcagaaa aattgccaaa tctcggaaat
    11761 ggtgagacag aaaattgccc aactcctact caacagagag gctcttacac atatcgcttc
    11821 taaattagcc atctctacct ctacctctac cgtctatcgt aagctcaagc aatttcattt
    11881 ccaagaggat tacaccactt tgcctgaaat cctctcctgg gatgaattct cctaccagaa
    11941 ggggaaattg gctttcattg ctcaggattt caacactaag aaaatcatga ccattcttga
    12001 taacagacgt caaacaacca tccgaaatca tttcttcaag tactcgaaag aagctagaaa
    12061 aaaagttaaa gtcgtcactg ttgatatgtc tggaagttat atccctctca ttaagaaatt
    12121 atttcccaat gctaaaattg ttctcgatcg tttccacatt gtccaacaca tgagcagggc
    12181 tcttaatcag actagaatca acatcatgaa gcaatttgat gataaatctc tggaatacag
    12241 agctcttaaa tattactgga aatttatcct aaaagatagt cggaaactct ctcttaagcc
    12301 tttctatgct agaactttca gagagacctt aactcctagg gagtgtctga agaaaatctt
    12361 tactctagta cctgaactta aagattacta tgacctgtat caactactcc tatttcatct
    12421 acaagagaag aatactgacc agttttgggg cttaattcaa gacacgttac ctcatctcaa
    12481 ccgcaccttt aaaaccactt tgagcacatt tatttgctat aaaaactaca tcactaacgc
    12541 cattgaattg ccttattcta acgctaaact tgaggccact aacaaactca tcaaagacat
    12601 caagcgcaat gcctttggtt ttcggaactt tgaaaacttc aaaaaacgga tttttatcgc
    12661 cctgaacatc aaaaaagaaa ggacgaaatt tgtcctttct caagcttagc tttttttcaa
    12721 cccactacag ttgacaaaga gcccaaaaac attgcatatt gcgccgaagg aattgctcat
    12781 actatcccaa gcacaaaacc ctcagtcgtt tgaccgaggg ttccttttta ttattcaaga
    12841 acttgattag ctcaatgcat ccaaggcgtc atccattgaa agaacttcgt ggaagacacg
    12901 ttgtgtcaat tcagtttttt gttctggagt gaggtattta gtgtttacac agtatccaga
    12961 gatacgtacg ataacgtctt cgcctgacat gattttttcg taaacatcgt tcaagtccat
    13021 aacgttcaag ttaacgtgtt gtccaccgtt ttcgaagtaa ccatcaagaa ttgttaccaa
    13081 gttatcaact tgttcatcac gagtcttacc aagagcgcga ggtgatactt gtgtagtcaa
    13141 tgagataccg tcagctgcat aactaaagtc aaggctagaa agtgagttca agttttgcaa
    13201 ccaaccacct ttagctttgt tagatgggtt agcacctggt gagaagaatt caagtttaga
    13261 caagttcaca gaaccatctt cgttgaggta tacacctttg tgaactggtg agttaccagt
    13321 ttgtttagag taagcaacgt tagatgtgat tgtcaaaagt gatactgtag cttctgcgtc
    13381 tttgtatagt ttgtggctac gtagacgagt tgtgtaagct tcgatcaacc attctgccaa
    13441 ttcgtttgaa cgtgggtcat cttcacccca gcgtgggtag tcaccgattg tttcgtaatc
    13501 gtagatgtag ccatcttcgt cacggattgg tttaactgta gcgtatttga tagctgacaa
    13561 tgtatcaaca gtgttagcaa atccacagat accgaatccc atgttggcac gttgtttagt
    13621 tggcaagaag gccatttgaa cagcttcgta gttgtaccta tcagtcatgt agtggatgat
    13681 gttcaaggca tctacgtaag tgtcagtcaa ccagtcaaga gatttttcaa agttcgcttt
    13741 aactgattca aattcaagaa cttcgtcacg gattggttcg atatcaaata ctttgtagtc
    13801 tttgtgaaca tcgtcgtaac caccattcaa accagtaaga agggctttaa gaacgtttac
    13861 acgagcaccg aagtactgga tgttgtggcg ttgttcttca ttttctggat caagtggaga
    13921 cacacagcat gagatacagc tcatttcacc atatccgtct ttagccattg ttgttacacc
    13981 ttcgtattgg atagaagagt gtttgtggct catgtgcata cagtagcgac ggaagttgta
    14041 tggcaatttg tcagtccaaa gaactgtcaa gtttggttct ggtgagttac cgatgttgtc
    14101 aagagtgttc aagaaacggt agtccatctt agtaacacgg tgacgaccgt cgttacccat
    14161 accagccata gaagttgtga taaaggttgg gtcacctgag tacaattggt cataagcttt
    14221 tgtacgagca aatttaactg tacgaagttt cataacgaaa tcatcaacga attcttggat
    14281 ttctgattca gtaaatgtac cacgagcaag gtcacgttct gcaaagatgt ccaatacgat
    14341 tggtacacga cctagagatg tagcagcacc gttaatcaca cggcagacag ccatgaaagc
    14401 aatgttaacc cattggattg cttctttcac gttcatcgct ggtttgcgaa catcaacccc
    14461 gtaaaggtca cccaggcgaa caacttgttg caatgcttgg tattgaaggt ttacttcttc
    14521 acgaagacgg attgtttctt catcgatttc tttgattgca ttccagtcat ttactttttc
    14581 ttgcatcaag tagtctgcac cgtaaagagc aagacgtgcg taaacaccga tgatacgtcc
    14641 gcgtgagtat gcatctggaa gaccagttac agtgtgtgcg tgacgagcgc gacgaatatt
    14701 tgaagtgtag gcacggaaaa taccgtcgtt aactgttgtt acatatttag tgaagatttc
    14761 gtgaacagct gggtctggtt cgtatccatt ttctttcaaa gtagtttcag ccatacggat
    14821 accacctttt ggcatgaagt tcaatttgaa gagttcatcg ttttggatac cgaagataac
    14881 ttcattttct ttgtcgataa atccagcagg gatatcagcg atagatgttg gacgagtgtc
    14941 cattgggaaa cgagtttctt cgtagtgtgc tttagtttct tctacaattt tcttgatgtg
    15001 aagtgaacgc tctgttggtc ctgcaaggaa gctttcgtct ccatcataag gtgtgtagtt
    15061 agcttgtaca aatcgtgata cacttgcttt ttctttccaa tctacgcctt tgaagccttc
    15121 ccaagctttg tcaaaaatat cttgtgcttc aacaactgtc ttaacaacca tattaatgtc
    15181 ctcttttttc tagtaacagt catctgttac attcataaga caagtatacc atatagtaac
    15241 cgatttcaac aagtgaaaat tccctatttt tacactttct tttctaaaac agtctatatt
    15301 ttatttcaaa ctgtattata tttttgaaaa aataaagtcc ttttttcttt ttttcagaaa
    15361 aaagggtata ataaaagaaa ataagcagta acactcaatg gaaatcgaaa agcaaactag
    15421 gaagctagcc gcagattgct caaaacactg ttttgaggtt gcagatagag ctgacgtggt
    15481 ttgaagagat tttcgaagag tataaaaagg tgctaggcat gttgattttt cctttgttaa
    15541 atgatttgtc aagaaaaatc atccatattg acatggatgc cttttttgct gcagtggaaa
    15601 tcagggataa tcctaaactc agaggaaaac ctgtcattat tggaagcgac cctcggcaaa
    15661 caggtggacg gggagtcgtt tctacctgta gttatgaggc aagagctttt ggtgtccatt
    15721 ctgccatgag ttccaaggaa gcttatgaac gttgtcccca ggctgtcttt atctcaggga
    15781 attatgagaa atacaagtct gtgggactcc agattcgagc tatttttaag cgctatacag
    15841 atttgattga acccatgagc attgacgaag cctatttgga tgtgacagaa aataaactcg
    15901 gtatcaagtc agcggtcaaa attgctcgcc tcattcaaaa agatatctgg caagaactcc
    15961 atctaactgc ttccgcaggc gtttcttaca acaaattctt agctaaaatg gcgagtgatt
    16021 atcaaaaacc acatggtttg acagtgattc tacctgaaca ggctgaggat tttctcaaac
    16081 aaatggatat ttccaaattt catggagtag gaaaaaagac agtagaacgt cttcatcaaa
    16141 tgggcgtttt tactggtgct gatttacttg aagttcctga ggtaacccta atagaccgtt
    16201 ttggtagact aggctatgat ctgtatcgaa aggctcgtgg cattcacaac tctccagtca
    16261 aatccaatcg catccgtaaa tcaatcggca aggagaaaac ctacgggaag attctccttg
    16321 ctgaggaaga tatcaaaaaa gagctgactc ttctatcaga aaaagtcgct ctcaatctac
    16381 atcaacaaga aaaagctgga aaaattgtca ttttgaaaat ccgctacgag gacttttcaa
    16441 ctcttaccaa acgaaaaagt cttgctcaaa aaacacaaga tgctagtcag ataagccaaa
    16501 tagccctgca actctatgaa gaattaagca agaaagaaag aggtgtccgc ctattgggga
    16561 ttaccatgac tggattttaa agctcaatga aaatcaaaga gcaaactagg aggctagccg
    16621 caggctgctc aaaacactgt tttgaggttg cagataaagc tgacgcggtt tgaagagatt
    16681 ttcgaagagt ataaaacctt gaagagttgc cccttcaagg tttttcttat acaaataaac
    16741 ggacaaaact gtaaagtagc aaaacactac caagcacgat acggtattta ccaaaaaggg
    16801 tgaagtcgtg ttttttcaca tagctggtca agaagcgaat agccaccatg ctgaccgcaa
    16861 aagctactcc catcgcgacc aagagcaaaa acaattgccc aaagctcaag agttctccgg
    16921 ctttcacaaa tttgaaaatc tttaaggcac tagctccaaa cataacagga atcccaagat
    16981 agaaggtaaa ttctgtcaca actgaacgac tggttccatt taacaaacca ccgacaatcg
    17041 ttgcacctga acggctagtc cctggtaaaa gagcaagaac ttggaagagt ccgatataga
    17101 aagcggtcgt ataaggaagc ttgtccaact ctgttacact tggctcgata gcacgcgctt
    17161 tattgcgctt ttccaaatag atgaaggcaa ccccgtagat aatcaacatg agagcaactg
    17221 aaaccatgtt atggaagtgg gtatcaaacc aatcatcaaa tttaaagaca ccaagtaaag
    17281 gtaaagtagc aatcaagacc ttcaaccata gtctccaagt cttacgaact tcctgtttgt
    17341 ccttggtcgg tttaaaagga ttgagcttgt taaaataaat caccataact gctaaaatag
    17401 caccaagctg aatcacgaca ttaaacatgg acataaaggc ttcattttga ttttggtatt
    17461 ggatgaattc ctctgctaaa atcaagtgac ctgtactgga aatcggcaac cattccgtaa
    17521 ttccttcaac aattccgaag aagatagatt ttaaaatttc aataagatac atagattact
    17581 ccctatatta tatttagcgc agttagctac tgccaaagcc caagtggtat acttggaata
    17641 agccactatg gattagttca tttcctccaa tcgcttgacg atttccgaaa ggctctaacc
    17701 acagcttttg tttcaattgg taatgagttt gataacgcat agacgtttga tctcgtctaa
    17761 ggtaacaagg caaaaaattc gtggataacc aagtagactt gaaatactat atctggaggt
    17821 actcccatgc tttatgtagg cattgatatc gctaaaaata aacacgatgt tacagccttg
    17881 aatgttccag gaaaaactgt tcttaaacca ctcacttttt caaataataa agctggtttt
    17941 gaactcttag atctgtctat tcgacagatc aaccaagact gtctcatcgc tcttgaagat
    18001 actggacatt atgcctttaa tctactgaac ttcctgcatg aacaaggata taaagtttac
    18061 acctacaatc ctttgctcat caaggaattt gccaaatcat tatcacttcg caagactaaa
    18121 acggataaga aagacgctca tggcatcgct cttaaacttc tttctgaccc caatcgtgaa
    18181 caatttcaac acgataatcg gcaagtagac ctaaaaatac tggctagaca tattcatcgt
    18241 ctcaagaaaa acagtctgat tggaaagtac aatacactcg ttgtcttgat atcatctttc
    18301 ctgagttgga taaaatcgtt ggaaagcatt cagaatatac ctaccaactc ttgacacgct
    18361 accctaatcc tcagaaaagg attgaggcag gatttgataa gctgatagaa attaagcgat
    18421 tgaccgcttc taaaattcag gatatcctct cagtcgcacc tcgttctatc ggaacaacat
    18481 ctcctgctcg tgaattcgaa atcatcaagc attacaagag gctcattgac aaggcggaaa
    18541 catgtatcaa tgactcgatg gctgagttca actcggtcat cacgacggtt actgggattg
    18601 gggatcgttt agggcggtca ttttagccga gattcgaaat attcatgcct ttgataatcc
    18661 tgctcaatta caagctttcg ctggactgga ttcttctatt tatcagtcag gtcagattga
    18721 tttagctgga agaatggtca aacggggttc ccctcatctg cggtgggcac tcatacaagc
    18781 tgccaaatca tgccctcgct tttcacctgc ttctaaggcc tatcttaaga ctaagttaga
    18841 ataaggaaaa cattacaatg tagccatcat ccaccttgca aaaaaactta tccgaaccct
    18901 gttttatatc ctaaaaaaga gctgccattt gacgaacaaa aagtgatgta atttctgaaa
    18961 ttaacacagg attacctttg aaaaaatgga ctttttcaag ggctttttgc cgtgctctaa
    19021 aatcatcgcc aaatcatcaa attgaaataa gaaatagttt agataaaact attgactttt
    19081 cttatagttt gtcttttttc tatcttccat tatatcatac tttttcagtc tatggtagct
    19141 ctctttaaaa ggcaccgata ctgccgccac ctccgcctcc agagaagcca ccaccagaac
    19201 ttccacttcc agaagataca gagtaggtgc ttgctgtatt tgcgacacta gcataatggc
    19261 tcatttgtgc tgttgaatga taaaacgtac tgtgccagcc ataagctaca tagagattga
    19321 tatctggatt ttccacttga atctgatgaa ccttcatcaa atgactaacc ttgtccgcat
    19381 agccaaataa ggtcgcatag accaagaggc gattccagac cacaatactt tccagttcag
    19441 cctgatccaa tcgtgcaatc tcacgcaaca tattttcaaa actggtccag agatagtaga
    19501 cctcagctcc cgcttcattt agaacaccat cacgattatc tagtcgaagc ttccaataat
    19561 agaaaacaga caaaactaac cctagaaaac caagtattgg caaagggagg taaagatagc
    19621 catgaacgtc taaactgtac aagaacaaac caaatccgat aaataggggc aggatagtca
    19681 aggcacccat acccacttgc aaggcctttt ccccaccagt taaaggacga taataatctg
    19741 ggagccccca gaaggaaact cgttttctca ctccttcttg catctggttc aatacctctt
    19801 caaaagaaga tttgagttga agccctcttg cttgaatccg tttttcatca gaaactttgg
    19861 ctctacgata aagactatca gataccttgt aatccgcaaa caaattggaa agagtttctt
    19921 cttttttacc tgaaaaagct agatttaggc agtctttctc aaagcttgac aaaccatctt
    19981 cttttactag cctcaaacca actgcatctc cttctgaaat gatagagaca ttcccacggt
    20041 ctatcacatc tagcaaggta gcttgaataa gttgatcaaa ggtgaatttt ccagctccct
    20101 tgaccaaggg actcacttcc tccaaggagg tcgagtagac tgcttctgat aaaaccatag
    20161 gctctaattc cattggtggt tcatagagac gatgattttt ggcatatttg actgaaggag
    20221 tggtctttct tctataaata aaatagaagc agacactcaa taacaaggag atggaaagga
    20281 tcgaagggag gacccaagta acgagttgtt tactctgatc tttttctcta acaatcgagt
    20341 cttctatctt attaaactct tctaaacgat tccctttcaa tccctgatcc ctagcgctag
    20401 caaaatcggt ccgaggccaa taggcatgca actcaactcc acgcttagcc ggaagattgt
    20461 ctaaacggat agtataatca aggttactct tttcaatcgt tccctctcta aaaagtttcc
    20521 ctgtatggaa aaagagtttt tcagccccct tgtctcccct tacatgaaat tcaaactttt
    20581 caatagactc tgaactatct gtcagaggtt gccaatttaa ttcagcgata tcatcataaa
    20641 ggaaaagtaa attttttaag ttccagacga ggtcaacttc aactatgtcg ccctcctgac
    20701 ctggattata gactctcaca gtataaccat ccgcttcttc tgttacttcg ctagtcacat
    20761 ctgctagttc tgcaccgttt ttcgcggcct gaatctttgg atgagggtca atgtcaaacc
    20821 cgctaggcat cttaccagca cgtccaagtc ccacgatttg gcccttaaag tcctcctcaa
    20881 actggtaaac tatcttctgt ctaaactctg ccgtattgtc tgcatgaata tacaaatccc
    20941 cttgataaga gtttatcttg aaatcaatgg caaaaacaga gagtggaaga aggcaaaaca
    21001 agcctaacac cagtaagaaa aaagtttttt tcatcaacta agcccccttt ttatctttct
    21061 tatcattata gcattttttc gtaagtaaag acttacttat gttgaaaaat tacgcatttt
    21121 tcgataaaat aggagacagt tattttttaa tagatcagaa taggagaaat catgagaaaa
    21181 atatacttat ctattttcac aagtctcttg ctgatgctag gacttgtcaa tgttgctcaa
    21241 gccgatgaat atttacgcat cggtatggaa gcagcatatg ctccctttaa ctggacccag
    21301 gatgatgata gcaacggagc tgtcaaaatc gatgggacca atcagtatgc caacggatac
    21361 gatgttcaaa tcgccaagaa aatcgctaag gacttaggta aagaaccttt ggttgttaaa
    21421 accaagtggg aaggtctagt ccctgccctt acttctggta agattgacat gattatcgca
    21481 ggtatgagtc caactgcaga acgcaaacaa gaaattgcct tttcgagcag ttactatact
    21541 agcgaaccag ttttgcttgt caaaaaagat tctgcctacg caagtgctaa atctttggat
    21601 gactttaacg gtgcaaaaat cacttctcaa caaggggtct acctttataa cttgattgca
    21661 caaatcccag gtgctaaaaa agaaacagcc atgggagact tcgctcaaat gcgacaagct
    21721 cttgaggctg gtgtcattga tgcttatgtt tctgaacgtc cagaagcact gactgctgaa
    21781 gctgcgaact ctaagttcaa gatgattcaa gtagaacctg gtttcaaaac tggggaagaa
    21841 gatacagcta tcgctatcgg gcttcgtaaa aatgacaatc gtattagcca aatcaatgcc
    21901 agcattgaaa ccatttcaaa agatgaccaa gttgccttga tggatcgtat gatcaaggaa
    21961 caacctgccg aagctacaac aactgaagag actagcagta gtttctttag ccaagttgct
    22021 aaaattcttt ctgaaaactg gcaacaactc ttgcgtggtg ctggtatcac tcttttaatc
    22081 tctatcgtcg gaaccatcat aggtctcatt attggacttg ccattggtgt cttccgtact
    22141 gctcctctct ctgaaaacaa agtcatttac ggcctacaaa aactagtcgg ctgggttctc
    22201 aatgtctaca ttgaaatttt ccgtggtacg ccaatgattg ttcaatcgat ggttatctac
    22261 tatggaactg cccaagcttt cgggatcaac cttgaccgta cactggctgc tatcttcatc
    22321 gtttcaatca ataccggtgc ctacatgact gaaatcgtcc gtggtggtat cctagcagtt
    22381 gacaagggac aatttgaagc tgcgactgct cttggtatga cccataacca gaccatgcgt
    22441 aagattgtcc tacctcaggt agtccgtaac atcctacctg caactggtaa tgaatttgtc
    22501 atcaatatca aagatacatc tgtattgaac gttatctctg ttgtcgaact ttatttctca
    22561 ggaaataccg tggcaacaca aacctatcaa tacttccaga catttacaat catcgccgtg
    22621 atttactttg tcctcacctt caccgtaaca cgtatcctac gctttatcga gcgcagaatg
    22681 gacatggata cctacactac aggtgctaac caaatgcaaa cggaggattt gaaataatga
    22741 cacaagcaat ccttgaaatt aaacacctca aaaaatccta tggacaaaac gaagtgctaa
    22801 aagacatttc actcactgtc cacaagggag aggtcatctc tatcatcgga agctctggaa
    22861 gcggaaaatc gaccttccta cgctccatta acctacttga aacaccaact gatggacaaa
    22921 tcctttatca tggacaaaac gtcctcgaaa aaggctatga cctcacgcaa taccgtgaaa
    22981 agttggggat ggttttccaa tcctttaacc tctttgaaaa tctcaatgtt cttgaaaaca
    23041 caatcgtcgc tcagacaact gtcctaaaac gcgaacgcac agaagctgaa aagattgcca
    23101 aagaaaacct ggaaaaggtc ggcatgggag aacgctactg gcaagccaaa ccaaaacaac
    23161 tctcaggtgg tcaaaaacaa cgtgtggcca tcgctcgtgc cctctccatg aatccggacg
    23221 ctattctctt tgatgaacca acatcagctc tcgatccaga aatggttgga gaagtcctca
    23281 aaatcatgca ggacctggct caggaaggct tgaccatgat tgtcgtaacc catgaaatgg
    23341 aatttgcccg tgatgtctct caccgtgtta tctttatgga taagggcgtg atcgctgaag
    23401 aaggtaaacc agaagacctc ttcaccaatc ctaaagaaga ccgaacaaaa gagttccttc
    23461 aacgctatct caaataaaaa gaaaaggctg catcaaccgt gcagtctttt tgctgtcctc
    23521 aaaatgaaaa ggcagattct ctatctctac tacttgaagg tcaagaatcc gccgttatcc
    23581 aaagattaat cttcaaattt ttcataattt ttttcataga aatcaattag gcctagggct
    23641 gtttcaaatg aaatattttt tacttttgca cgaccctgcg ccagagcaat gatagacatt
    23701 tcacgcgcat tcgtttcttt agagatacgg tagcctgtga ttttcttatc acgaacccag
    23761 ccaacaactg attctacttt ttcaaagttt gacttagcca tgtttttctc ctattttctt
    23821 ctttataata tttaattgta tacgttttta ctacttttgt caataaaaaa aacatatatt
    23881 caacgaaaat aattagttca gaattttctt acttcctttt taaatccgat aatatatagg
    23941 ttttgctagc ctctacacca taaatatttg ctaataaaaa tactgtatta ttaccctctt
    24001 aaggtgcgaa attattcaag ttcttaaaaa atgcttctct atttccgtaa gatagcttat
    24061 ttcttcgatt taagaactga agatgatagt tctaaccttt agaaatccaa gccttcacta
    24121 gctcaaaaac tcctatcttt cttcctcaat aaatcatctg agagataggt attccttatg
    24181 tccttcaaat tcatcactcc tttggatatt gaggtgctag cctagaagca gacacccgat
    24241 tatctaaacc atccttaata gagatgacaa gacagataag ctcagttaat tacttatata
    24301 tctttttaat atagtatatt tgtcaacaaa aagaaatcaa atcatacctt atactcaatg
    24361 aaaatcaaag agcaaactag gaagctagcc gcaagttgct caaaacactg ttttgaggtt
    24421 gcagatagag ctaacgtggt ttgaagagat tttcgaagag tattaaagac agtgtgacta
    24481 tgcttgtcaa tagataggaa atcaaaatga aggtatgata tttttttatt agtcctcaga
    24541 caagcatatt ataaagcgtt tcattaccat ttaagttaat ataagctgga tcaaaacctt
    24601 ccattctacg aatcaaacct gcataatcat gcttatctgc taaagcgatc ccaattaata
    24661 ctgggcctgt tcccttgcta gctcgtttga tatactcaaa acgtgtgata tcatcatttg
    24721 gccccaggat atcatttaca aactcacgca aagctcctgg acgttgtggg aaattgacca
    24781 caaagtaatg tttgatacca tcataaatca aggcacgctc ttccatttct ggcatacggt
    24841 tgatatcatt atttcctcca gaaatgatac aacaaatggt tttcccctta atatattcag
    24901 ctaaaacctc taaagaggcg atactagccg ctccagcagg ttctgcgact atcccttgct
    24961 tagagtaaag gtcaatcaag gtttcagaaa tcaatccctc atcgacacct accaaagttt
    25021 taatatgttg acgagttgct tcataggtca actgacctac cttttgcaca gcaatcccat
    25081 cagcaaattt atcaatttcc ttgagtttta ctggacctcc agcctcaaag gcagctttca
    25141 tggaacgcgc tccattcgcc tctactccga taacctcaat ctctggactt gtttccttga
    25201 tataggtaga aaccccggca atgagaccgc caccaccaac aggaaccaag acagcatcaa
    25261 aatcaatcga ttcttttcga gcttcttcta aaatctcata agcaactgtt ccttgacctg
    25321 cttgaacatg agcatcatca aaaggatcaa taaaggtacg attttcagag actgtaaatt
    25381 cttgagctgc tttggctgag gcatcaaagg tatctccaac tagtttaata gttacaaaat
    25441 ccccaccaaa aaagcgaacc tgaccaatct tttgttgtgg cgtagtaatg ggcataaaga
    25501 tagtagcagg aattttcatt tcattacaag tataggctac tccctgcgca tgatttcccg
    25561 cagaagcgca gactacccca cgttcacgtt cttccttgct gagctgggaa atggcataat
    25621 aggcaccacg aattttaaag gagcgaacac gctgggcatt ttcttttttc aaataaatct
    25681 tagcaccata cttctccgat aaataatgat cgtaatccag tggagtattc acaaccacac
    25741 cgttcaagac cttgtgagcc ttgattatat cttttgaact taacatataa aacctctttt
    25801 tctataaaaa acagtcacta atgactgttt tttagttatt catctccgaa aacttcagta
    25861 acactttcat ggtatttatg agccatacga atcgaaaact ctttaggaag ttcataacga
    25921 tttgtggaaa tccaatcata taaccattct accaaacttt cttcactatc attacgatgg
    25981 aagataaaat agtttaaaat ttctttatat tctacatcat tcaaatccaa cgtgtctaca
    26041 aattgactac gaggaacaaa attagaatct aattttctta gttgatctgt caattctccc
    26101 aattgtaaat ccaactgaaa aaatagtttt tgcagttgcc tatcagtttc atcacatcct
    26161 gtcttgatag aaaacaaatt ggtaatattc atatgatttc aacccctaaa taagtacatc
    26221 taatatccca cgaatagctg aagctaaagt tttcgcagtc cagtcattta aacccgattc
    26281 tttcaatcca gatgcaataa tttgctctat ttgatataaa ccgccatcta tcgtctcatt
    26341 tattctgcga agaggacctt caatatagga taaagcttct ccgaatctaa cagctgattt
    26401 aggtcctaat gatttaccaa ctatatttgt taatgttttt tatttctcaa aatccatttc
    26461 gctatataac gagcagattt agtcgcacca gctctctcaa acggagaatg aatttcaaga
    26521 ccttcttctc tagctatttg tgccaatttg aagaattgtt caaagttcat atgcaaccta
    26581 ccatcttcaa aattagcatc atcataaatg ttaattacag cattttcatc atacgaccaa
    26641 tctgctttat tttggtctgc tagcactatt accgacggtg taattacatt atacaactag
    26701 aaccaataat aacgatgcaa tttttctcat aatctttttc ataaaatcat ctccagcgct
    26761 atatatttct aattagttat agattttgaa tgcatcatcg tcgtttttac caacgaatgg
    26821 cattgcttta cgcaattctg caccaacttt ttcaatttca aggttagctg cttgttcacg
    26881 gtaagcagtc aattttggac gtccagcttt atagtcattt acaaagtcat ttgcaaattt
    26941 accattttgg atgtctgcca agacagcctt catattttct ttaacttgtt cagtgattac
    27001 acgtggacct gatacatagt caccgtattc agcagtgttt gaaatagatt gacgcatttt
    27061 cttgaatcca ccttcgtaga tcaagtcaac gatcaatttc atttcgtgaa gaacttcaaa
    27121 gtaagccaat tctggagcgt aacctgcttc tgtcaagact tcgaaacctg cttcgataag
    27181 ggcagtcaaa ccaccacaaa gtacagcttg ttcaccaaac aaatcttctt cagtttcttc
    27241 tttgtaagtt gtttcaagaa gacctacacg agccgctcca acacctttac accagtccat
    27301 agcaatgttt ttagcatttc ctgttgcatc ttggtatact gcataaagag ctggaacacc
    27361 aaatccttct tcgtaagtac gacgtaccaa gtgtcctggt cctttaggag cacacatgaa
    27421 gacatctaca tccgcaggaa ctttgataaa ttcaaagtgg atgttgaaac catgggcaaa
    27481 tccaactgcg tttccagctt ccaagtttgg agcgatttct gcttcgtaca attcttgttg
    27541 aatttcgtct ggcgccaaga tcatgataac atcagccaac ttagtagctt ctgctactgt
    27601 gtaagtatca aatccatctt cttttgcttt atcaaaagat ttacctggac gtacaccgat
    27661 aataacgtca cgacctgaat cacgcaagtt ttgagcatgc gcatgccctt gtgaaccata
    27721 accgataacg gcgatttttt taccgtcaag tgctgctact ttaacatctt tttcatattc
    27781 catttgaact gtcatagctt ttctctcttt tctattattt attgcctttt aggctggttt
    27841 aataaattta agttggattt ttaatcgcgg gtaaatccag ttgcacccgt tcgagcaata
    27901 ttgcgaatac cgtatgggcg aatgactcgc aatagggctt cgctcttttc tgcatttccc
    27961 gtcatctgaa tggtaatcga gcttggcgct acgtctacta ctgttgcacg gaaaggttga
    28021 ataatcgcta aaatctcagc tctcttctca gctggcgctg acatcttaac caaaatcacc
    28081 tcgcgctcca aatgaggctt gtctgtaata tctcgaatgc gaatcacatc aatctgacga
    28141 ttgagctgtt tgatgatttg ctccacttca tcatgagaag caacatcaat aataatagtg
    28201 atacgcgata cattcggatc ttctgttgct ccaacagaga tgctttcaat attaacctga
    28261 cgacgagata ggacacctgt aaagcgattg aggactcctg aacgattttg tagttttgct
    28321 gttaacattc tacgcatgga actgcacccc caacatctca tgattactct taccagccgg
    28381 taccattggt aacacctgtt ccttacgaga aatatctacc tcaattagca taggaacatc
    28441 ctcagtgatg acttcaaggt cttgagccaa ggtctcagga ttgtcaaact tatagttttt
    28501 aataccataa gcctgcgcca tcaattggaa atcaggaagg gtatcaaaga ccgactctga
    28561 tgttctgcct tcatagaagg attcctgcca ctggcgaacc attccaagtg aatgattgtt
    28621 cagcataacc accttgattg gcaccttgta aatattcaaa atagccaact cctggttggt
    28681 catttggaaa ccaccatccc caacaaacaa gactacttcc ttatctgggt tagcaatttt
    28741 agcaccgatt gctgctggaa ttccaaagcc cattgttccc aaaccacctg aagtcactaa
    28801 ctgacgttca ttttggtagg gataatactg agctgtccac atttggtgtt gaccaacgtc
    28861 tgttaccaca atggcatctc cattcgtcaa ttcaccaatt cgttcaataa ctgcttgcgg
    28921 ttgaaccaca cgctctttct tatcataaga acgaacacga ttcttgtctt tagtgacttt
    28981 ctcaatccac ttttcagtgt tgttgtgaac tgttggttct gctagcaaca tttgcaaggc
    29041 cttcttagca tctccaacta caggaatgtc tgcactgata atcttgccaa tctcagctgg
    29101 gtcaatatca atgtgggcaa ccttagcatt cttagcgaaa gtcttaggat tccccgtcaa
    29161 acggtcatcg aaacgagaac caatactaat cataaagtcc gcttccgtca tagcaatatt
    29221 tgctgcgaat gacccgtgca tgcctcccat tccaagaaag agtgggtgac tcgttgcaat
    29281 cgttccttgt cccaaaagac tggttaccac tggaatttga tagcgttctg caaattcatt
    29341 tagttccgta gcagcctcag cataactaat tccaccacca gctaacaaga ctggcttttt
    29401 agccttggac aattgcttca agattttctt gatttgcata tcattcggct caagagtcgg
    29461 ctgataactt ggtaaattca cttctggtga ataaatgaag tctgtttcta aagcagatat
    29521 gtcttttggt aggtcaatta caactggccc tggacggcct gtagttgcga tatggacagc
    29581 ttccgtaatg atacgcggaa tatcagctgt ctcacgaact tggtaattgt acttagtgat
    29641 tggcatggta attcccacga tgtctgcctc ctgaaaggca tccttcccaa tccctgctcg
    29701 cgccacctga cctgtaaaga ccaaaagggg aacgctatcg ctcatggcat ccgcaatccc
    29761 tgtaatggca tttgttgctc ctggtccact agtgacgacg gcaacaccca actttccagt
    29821 tgatttggca taaccttcag cttcatgcaa acaaccttgc tcatggcgcc ctagaatgtg
    29881 gcgaatgcct ttaaaattat atatcgcatc ataaaaaggc aaaaccgcac caccaggata
    29941 accaaagatg gtatcaactc ctaaatcacg aagtgtttcc aaaactaggt ccgaccccgt
    30001 cttaggagat tctaaactga ttttctccat tattcccctt tctttcctct taaaaataac
    30061 ttgttactat cataccattt tttcaaaatt tttcaagata aaagaagaaa ttttctgaat
    30121 tttctatttt aacgtttatt tatgaatgtt atttttgttt ttattaaaaa gataccgatt
    30181 tcatttacta aaaagaaaaa agaactgatt tctcagtcct tcattaatct tattccacac
    30241 taaataggta tgggtaaaca ggttgttgac cttggtgaat ctcgacttca acgtcttcga
    30301 attcttctac gatttcttga gcgatttcat tggcaagttc ttcgcttccg tcttcaccta
    30361 catagaaggt tacgatttca ctgtcttcat ccaacatatg tttcaaggtt tcagtcaatg
    30421 tttggtgcat atcagggttt gacacaagaa tttttccatc caccatacct aaattatcgt
    30481 tttcatggat ttctaagcca tcgatcgttg tatcacgcac ggctgttgtg acgcttccgc
    30541 taacgacatc gctaagagca gctgtcatac gctcttggtt ttcttcaatg gacttgcttg
    30601 gatcaaaggc aagaagactt gtcatacctt gaggaagagt gcgagcctct accactaccg
    30661 ctggttgctc caaaacttct gccgcagatt gagctgccat gaagatgttc ttgttgtttg
    30721 gcaagaagat gatgttacgg gcattaacct gttcaacagc cttgataaag tcttctgttg
    30781 aagggttcat ggtttgaccg ccttcgataa cataatccac gccttgagaa cagaagatat
    30841 ctgctagacc tttaccagcc accacagcaa tcaaagcata ctctttttct tcagccgact
    30901 tgataacttg agtagcttct ttctcaacct gtgcttcgtg ttggttacgc atattgtcaa
    30961 cttttacctt gaccaagcta ccatatttga gaccttcttg cataacaagt cctggatctt
    31021 ctgtatgaac atggactttg acaatttcat catcgttaac aacaaggaga gaatctccaa
    31081 gctcatccaa gtagttacgg aattcatcgt agtcaaaatc tttagcatag gttggacctt
    31141 gcttaagagc taccatgatt tcagtacagt aaccaaacgt gatgtcctca gtcgctacgt
    31201 gaccagctac agacttatga tgctctacat tgatcatctc actcatgttg gcaggagtcg
    31261 ctacaaagtc ctcagatgca atatattcgc cagtaagggc tgaaaggaaa ccttcgtaga
    31321 tgaagaccaa tccttgacca cctgagtcca caacgccaac ttctttcaat actggaagca
    31381 tgtctggtgt tttagctaga gctgttttag caccttccaa ggctgcgcgc atgacttcaa
    31441 cagcgtcatc tgtttgctca gcttttttct tagcaccgat agcagctcca cgagaaactg
    31501 ttaaaatcgt tccttcaaca ggtttcatca ctgccttata ggcaacttcc acacctgatt
    31561 ggaaggccag agccaagtct tgacctgtta actcgtcttt atccttgata gcttgggaaa
    31621 atccacggaa aagctgagac gtaatcactc ctgagttccc acgcgcaccc atcaaaagcc
    31681 ctttggcaag aatgctcgct acttctccaa ctgtagaagc tggcttgtct gcaacttctt
    31741 tagcaccatt ttcaatggtc attcccatat ttgtcccagt atctccatct ggaactggaa
    31801 agacgtttaa tgaattgaca tattcagctt gcttattcaa gcgagttgat gcagcctgca
    31861 ccatttcttg aaataagcta gtagtaattt ttgacacggt tattctccta caactttgat
    31921 attttgaatg tagacattta cagtctgagc agtaattcca agctggtttt ccaagctaaa
    31981 ggcaacacgc tcttgaatgt tttttgacac ttcactaatc tttgttccgt agcttaacac
    32041 ggtatataca tcaactgcaa tactgccatc ttcggctgcc tttacgacga cacctttaga
    32101 ataattttcc ttacctagca gggcttggaa attatctttg agggcatttt tactagccat
    32161 accgaccaca ccaaaaatct cagttgctgc tccacctacg acggttgcaa tcacttcatc
    32221 tgttagttcg atttgaccat cttttgtatt aatttttaca gtcatccttt ttacctcaac
    32281 tagttgatac tctattttat catatttcag cccaagtgta aaagcagaat gatgtatcag
    32341 cggatattta ctctattttt caaacgatgt tatacccaca ataaaagaaa aaagacccta
    32401 aggtctcctt tgcttttatt attaaacgcg ttcaacttta cctgatttca aagcacgagc
    32461 tgaagcccaa acttttttag gtttaccatc gataagaaca gtaacttttt gaaggtttgg
    32521 ttttacggca cgttttgttt ggttcatcgc gtgtgaacgg ttgtttcctg atacagtctt
    32581 acgacctgta aagtaacata ctttagccat tgtgttttcc tcctattaga tctaatatag
    32641 cggatgtgct agcaccacat accgtactat gttatcacat tttcttgttt tttgcaaggg
    32701 aattggaaga ttttttattt gtgtcttaaa tcaggtcttg cgtgacattt tctgctctcc
    32761 acatgccatc gttgattaac agaacaccag aattaaaatt atgtgtataa aaatcatctc
    32821 taactgcagc taagggtata gccgtcaagt ccaaatccca cagctcatct atcgattttc
    32881 ttacaacaat atctgaatcc aaatacagta cacgagactc gcttacatac tttggaataa
    32941 aatacctaaa aaagccgcat atgaaagtcc ctcaaagggg agacgataac ctttcagaat
    33001 attactgtca atctaaacat tcacaatctc actattcaaa gtctctagtc ttttttccat
    33061 caattggaac cattctcgcg gaaggtcatc attaaaaaca taaaacttaa gattataatg
    33121 atgaacacaa agagatttta ttgttgtttc aactttatcc atataagcat tatctgcacc
    33181 taagacaatc gcttttttct cttctttcac tttttatctc atttcttttt attcccatca
    33241 tattattccc atcatatgtt tcccatcata tgtttctacg taaccattat tttcgcctat
    33301 tcgttcgtaa aaccatacca gtggagattt tagatgaagt cccattacgg tttacaattt
    33361 ttacattacg acacggagtt ttacaaatcg atttcatttg ccaaacgtag ttagtgaggc
    33421 agttagctag ttcgccaaat agcgactagc gtccaacaat ttggaacttt agttccaatt
    33481 gttggtactg agtcacatct tctcctctaa ctctacgtct ggatacttgt ccgcaaacca
    33541 gcggagggca aagtcatttt caaagagaaa gactggttgg tcaaaacggt ctttggctaa
    33601 gatattgcga cttgacgaca tccgttcatc caagtcctca ggcttgatcc aacgaacggt
    33661 ctttttaccc attgggttca taactacttc cgcattgtac tcgccttcca tgcggtgttt
    33721 aaagacttca aactggagtt gacctacagc gcctagcatg tactcacctg tttggtaatt
    33781 cttataaagc tgaacggctc cttcttgcac caattgctca atccccttgt ggaaggattt
    33841 ttgcttcata acattcttag cagaaacttt catgaaaatc tcaggtgtaa aggttggcag
    33901 gggttcaaat tcaaacttgt tttttccaac cgtcaaggta tccccaacct gataagtacc
    33961 ggtatcgtaa accccgataa tatcacctgc cacggcattg gtcacattct cacgactctc
    34021 cgccataaac tgggtaacat tagatagttt agccccctta ccagtacgag ggagattgac
    34081 actcatgccg cgctcaaatt cgccagatac gatacggaca aaggcaatac ggtcacggtg
    34141 acgagggtcc atgttggctt ggattttaaa gacaaagcct gagaaatcct tgtcataagg
    34201 atccacaatt tcaccgtctg ttttcttgtg accatgtggt tctggagcaa acttgaggaa
    34261 ggtttcaagg aaggtctgca caccaaagtt tgtcagggct gaaccgaaaa agacaggcgt
    34321 caattctcca gccagaatag cttcctctga aaactcattc ccggcttcat ttaaaagctc
    34381 aatgtcatcc ttgacttgct cgtagaaagg attgctacca aagagtttgt ccccgtcttc
    34441 tagactggca aaacgctcat cccctttgta aagctctaaa cgttggttat agaggtcata
    34501 caagccctca aaggctttcc ccatcccgat aggccagttc atagggtagc tagcaatgcc
    34561 caagatttct tccaattctt gcaagagatc caaaggctca cgaccgtcac ggtccagctt
    34621 gttcataaag gtaaagactg gaatgccacg atgtttcaca acctcaaaca atttcttggt
    34681 ttgagcctcg atccccttgg cagagtccac gaccatgacc gcagcatcca ccgccatcaa
    34741 ggtacgatag gtatcttctg agaagtcctc gtgccctggc gtgtctaaga tattcacgcg
    34801 cttgccgtcg tagtcaaatt gcataacaga tgaagtaaca gaaatcccac gttgcttctc
    34861 gatatccatc cagtcagatt tagcaaaagt ccctgttttc ttccctttta ccgtaccagc
    34921 ctcacgaatc tcacccccaa agtagagtaa ctgctcagtg atggttgttt tccccgcgtc
    34981 cgggtgggag ataatggcaa aggtacgacg tttcttaatt tcttcttgaa tattcataag
    35041 ttctctttct ttgattctct atttttcttg tttcaatagc tgagaatgat ttttacattg
    35101 gattttacca ttcctttcaa cactccatta tatcggattt tagcattttt ttcaatttct
    35161 atttcttttc acttccccct cccttattta taggaaaata tggtaaaata gaacagacta
    35221 aaaatcatca tttcacgaaa ggatgcaaga tgaaaattac gcaagaagag gtaacacacg
    35281 ttgccaatct ttcaaaatta agattctctg aagaagaaac tgctgccttt gcgaccacct
    35341 tgtctaagat tgttgacatg gttgaattgc tgggcgaagt tgacacaact ggtgtcgcac
    35401 ctactacgac tatggctgac cgcaagactg tactccgccc tgatgtggcc gaagaaggaa
    35461 tagaccgtga tcgcttgttt aaaaacgtac ctgaaaaaga caactactat atcaaggtgc
    35521 cagctatcct agacaatgga ggagatgcct aatgactttt aacaataaaa ctattgaaga
    35581 gttgcacaat ctccttgtct ctaaggaaat ttctgcaaca gaattgaccc aagcaacact
    35641 tgaaaatatc aagtctcgtg aggaagccct caattcattt gtcaccatcg ctgaggagca
    35701 agctcttgtt caagctaaag ccattgatga agctggaatt gatgctgaca atgtcctttc
    35761 aggaattcca cttgctgtta aggataacat ctctacagac ggtattctca caactgctgc
    35821 ctcaaaaatg ctctacaact atgagccaat ctttgatgcg acagctgttg ccaatgcaaa
    35881 aaccaagggc atgattgtcg ttggaaagac caacatggac gaatttgcta tgggtggttc
    35941 aggtgaaact tcacactacg gagcaactaa aaacgcttgg aaccacagca aggttcctgg
    36001 tgggtcatca agtggttctg ccgcagctgt agcctcagga caagttcgct tgtcacttgg
    36061 ttctgatact ggtggttcca tccgccaacc tgctgccttc aacggaatcg ttggtctcaa
    36121 accaacctac ggaacagttt cacgtttcgg tctcattgcc tttggtagct cattagacca
    36181 gattggacct tttgctccta ctgttaagga aaatgccctc ttgctcaacg ctattgccag
    36241 cgaagatgct aaagactcta cttctgctcc tgtccgcatc gccgacttta cttcaaaaat
    36301 cggccaagac atcaagggta tgaaaatcgc tttgcctaag gaatacctag gcgaaggaat
    36361 tgatccagag gttaaggaaa caatcttaaa cgcggccaaa cactttgaaa aattgggtgc
    36421 tatcgtcgaa gaagtcagcc ttcctcactc taaatacggt gttgccgttt attacatcat
    36481 cgcttcatca gaagcttcat caaacttgca acgcttcgac ggtatccgtt acggctatcg
    36541 cgcagaagat gcaaccaacc ttgatgaaat ctatgtaaac agccgaagcc aaggttttgg
    36601 tgaagaggta aaacgtcgta tcatgctggg tactttcagt ctttcatcag gttactatga
    36661 tgcctactac aaaaaggctg gtcaagtccg taccctcatc attcaagatt tcgaaaaagt
    36721 cttcgcggat tacgatttga ttttgggtcc aactgctcca agtgttgcct atgacttgga
    36781 ttctctcaac catgacccag ttgccatgta cttagccgac ctattgacca tacctgtaaa
    36841 cttggcagga ctgcctggaa tttcgattcc tgctggattc tctcaaggtc tacctgtcgg
    36901 actccaattg attggtccca agtactctga ggaaaccatt taccaagctg ctgctgcttt
    36961 tgaagcaaca acagactacc acaaacaaca acccgtgatt tttggaggtg acaactaatg
    37021 aactttgaaa cagtcatcgg acttgaagtc cacgtagagc tcaacaccaa ttcaaaaatc
    37081 ttctcaccta cttctgccca ctttggaaat gaccaaaatg ccaacactaa cgtgattgac
    37141 tggtctttcc caggagttct accagttctc aataaagggg ttgttgatgc cggtatcaag
    37201 gctgctcttg ccctcaacat ggacatccac aaaaagatgc actttgaccg caagaactac
    37261 ttctatcctg ataaccccaa agcctaccaa atttctcagt ttgatgaacc aatcggatat
    37321 aatggctgga ttgaagtcaa actagaagac ggtacgacca agaaaatcgg tatcgaacgt
    37381 gcccacctag aggaagacgc tggtaaaaac acccatggta cagatggcta ctcttatgtt
    37441 gacctcaacc gccaaggggt tcccttgatt gagattgtat ctgaggcaga tatgcgttct
    37501 cctgaagaag cctatgctta tctgacagcc ctcaaggaag ttatccagta cgctggcatt
    37561 tctgacgtta agatggagga aggttcgatg cgtgtggatg ccaacatctc ccttcgtcct
    37621 tatggtcaag agaaattcgg taccaagact gaattgaaga acctcaactc cttctcaaac
    37681 gttcgtaaag gtcttgaata cgaagtccaa cgccaggctg aaattcttcg ctcaggtggt
    37741 caaatccgcc aagaaacacg ccgttacgat gaagcgaata aagcaaccat cctcatgcgt
    37801 gtcaaggaag gggctgctga ctaccgctac ttcccagaac cagacctacc cctctttgaa
    37861 atttctgacg agtggattga ggaaatgcgg actgagttgc cagagtttcc aaaagaacgt
    37921 cgtgcgcgtt atgtatctga ccttggttta tcagactacg atgctagtca gttgactgct
    37981 aataaagtca cttctgactt ctttgaaaaa gctgttgccc taggtggtga tgccaaacaa
    38041 gtctctaact ggctccaagg ggaagtcgct cagttcttga atgctgaagg taaaacactg
    38101 gaacaaatcg aattgacacc agaaaacttg gttgaaatga ttgccatcat cgaagacggt
    38161 actatttcat ctaagattgc caagaaagtc tttgtccatc tagctaaaaa tggcggtggc
    38221 gcgcgtgaat acgtggaaaa agcaggtatg gttcaaattt cagatccagc tatcttgatc
    38281 ccaatcatcc accaagtctt tgccgataac gaagctgctg ttgccgactt caagtcaggc
    38341 aaacgtaacg ccgacaaggc ctttacagga ttccttatga aggcaaccaa aggccaagcc
    38401 aacccacaag ttgcccttaa actacttgca caggaattgg cgaagttgaa agaaaactag
    38461 acagaacaaa accagcccta aggttggttt tttcttctct accaactccc aataactatt
    38521 ttggctttat ttccagagta ttttatggta aaatgaagag taataatatt tattaaagag
    38581 gtaaaaacat gattgaagca agtaaattaa aagctggtat gacctttgaa acagctgacg
    38641 gcaaattgat tcgcgttttg gaagctagtc accacaaacc aggtaaagga aacacgatca
    38701 tgcgtatgaa attgcgtgat gtccgtactg gttctacatt tgacacaagc taccgtccag
    38761 aggaaaaatt tgaacaagct attatcgaga ctgtcccagc tcaatacttg tacaaaatgg
    38821 atgacacagc atacttcatg aatacagaaa cttatgacca atacgaaatc cctgtagtca
    38881 atgttgaaaa cgaattgctt tacatccttg aaaactctga tgtgaaaatc caattctacg
    38941 gaactgaagt gatcggtgtc accgttccta ctactgttga gttgacagtt gctgaaactc
    39001 aaccatctat caaaggtgct actgttacag gttctggtaa accagcaacg atggaaactg
    39061 gacttgtcgt aaacgttcca gacttcatcg aagcaggaca aaaactcgtt atcaacactg
    39121 cagaaggaac ttacgtttct cgtgcctaat ctctagaaag aggtcattct atgggaattg
    39181 aagaacaact tggcgaaatc gttatcgccc cacgtgtact tgaaaaaatc attgctatcg
    39241 ctactgcaaa ggtagagggt gttcactctt tttcaaacag atcagtgtct gatacccttt
    39301 caaaactttc actcggccgt ggcatttatc ttaaaaacgt ggacgaagaa ctcacagcag
    39361 atatctatct ctaccttgag tacggagtaa aagttcctaa ggtagcggtt gctatccaga
    39421 aagctgtcaa agatgccgtc cgtaatatgg ctgatgtaga actcgctgct atcaatattc
    39481 acgttgcagg tatcgtccca gataaaacac caaaaccaga attgaaagat ctatttgacg
    39541 aggacttcct caatgactag tccactatta gaatctagac gccaactccg taaatgcgct
    39601 tttcaagctc tcatgagcct tgagttcggt acggatgtcg aaactgcttg tcgtttcgcc
    39661 tatactcatg atcgtgaaga tacggatgta caacttccag cctttttgat agacctcgtt
    39721 tctggtgttc aagctaaaaa ggaagaacta gataagcaaa tcactcagca tttaaaagca
    39781 ggttggacca ttgaacgctt aacgctcgtg gagagaaacc tccttcgctt gggagtcttt
    39841 gaaatcactt catttgacac tcctcagctg gttgctgtta atgaagctat cgagcttgca
    39901 aaggacttct ccgatcaaaa atctgcccgt tttatcaatg gactgctcag ccagtttgta
    39961 acagaagaac aataaggctc tttgtcaact gtagtgggtt gaaaaaaagc taagctcgag
    40021 aaaggacaaa tttcgtcctt tcttttttga tgttcaaagc gataaaaatc cgttttttga
    40081 agttttcaaa gtttcgaaaa ccaaaggcat tgcgcttgat aagtttgatg agattattgg
    40141 tcgcttccag tttggcatta gaatagtgta gttgaagggc gttgacaatc ttttctttat
    40201 ctttgaggaa ggttttaaag acagtctgaa aaataggatg agcctgctta agattgtcct
    40261 caataagtcc gaaaaatttc tctggttcct tattctggaa gtgaaacagc aagagctgat
    40321 agagctgata gtggtgtttc aagtcttgtg aatggctcaa aagcttgtct aaaatctctt
    40381 tattggttaa gtgcatacga aaagtaggac gataaaatcg cttatcactc agtctacggc
    40441 tatcctgttg aatgagtttc cagtagcgct tgatatcctt gtattcatgg gattttcgat
    40501 gaaactgatt catgatttgg acacgcacac gactcatggc acggctaaga tgttgtacaa
    40561 tgtgaaagcg atcaagaacg attttagcat tcgggagtga aacagtctgg gagactgttt
    40621 cagcctgagc ctaggaattt gaaagcgaag ctgtttagcc aagtcatagt aagggctaaa
    40681 catatccata gtaataattt tgacgcgaca tcggacaact ctatcgtagc gaagaaagtg
    40741 atttcgaatg atagcttgtg ttctaccctc aagaacagtg atgatattga gattgttaaa
    40801 atcttgcgca atgaagctca tctttccctt tgtaaaagca tactcatccc aagacataat
    40861 ctcaggaaga caagaaaaat catgtttaaa gtgaaaatca ttgagcttac gaataacagt
    40921 tgaagttgag atggaaagct gatgggcaat atcagtcata gaaatctttt caatcaactt
    40981 ttgagcaatc ttttggttga tgatacgagg gatttggtga tttttcttga cgagggaagt
    41041 ctcagcgacc gctatttttg agcactgata gcacttaaag cgacgctttc taaggaggat
    41101 tctagtaggc ataccagttg tctcaaggta agg
//
LOCUS       DAVFER010000018        39951 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1105170250
            SAMEA2167659-rid19724873.denovo.018, whole genome shotgun sequence.
ACCESSION   DAVFER010000018 DAVFER010000000
VERSION     DAVFER010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2167659
            Sequence Read Archive: ERR388902
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 39951)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 39951)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928716.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928716.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 04:07:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,118
            CDSs (total)                      :: 2,073
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 120
            CDSs (without protein)            :: 120
            Pseudo Genes (ambiguous residues) :: 0 of 120
            Pseudo Genes (frameshifted)       :: 67 of 120
            Pseudo Genes (incomplete)         :: 47 of 120
            Pseudo Genes (internal stop)      :: 34 of 120
            Pseudo Genes (multiple problems)  :: 23 of 120
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..39951
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2167659-rid19724873.denovo.018"
                     /strain="1105170250"
                     /db_xref="taxon:1313"
     gene            1..518
                     /locus_tag="VU534_000965"
                     /pseudo
     CDS             1..518
                     /locus_tag="VU534_000965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="internal stop; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
     gene            complement(511..684)
                     /locus_tag="VU534_000966"
     CDS             complement(511..684)
                     /locus_tag="VU534_000966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001022221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteinase"
                     /protein_id="HEU1513573.1"
                     /translation="MNIKKRVLSAGLTFASALLLAACGQSGSDTKTYSSTFSGNPTTF
                     NYLLDYYADNIVN"
     gene            complement(843..2450)
                     /locus_tag="VU534_000967"
     CDS             complement(843..2450)
                     /locus_tag="VU534_000967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HEU1513574.1"
                     /translation="MQEKWWHNAVVYQVYPKSFMDSNGDGVGDLPGITSKLDYLAKLG
                     ITAIWLSPVYDSPMDDNGYDIADYQAIAAIFGTMEDMDQLIAEAKKRDIRIIMDLVVN
                     HTSDEHAWFVEACENTDSPERDYYIWRDEPNDLDSIFSGSAWEYDEKSGQYYLHFFSK
                     KQPDLNWENEKLRQKIYEMMNFWIDKGIGGFRMDVIDMIGKIPDEKVVNNGPMLHPYL
                     KEMNQATFGDKDLLTVGETWGATPEIAKFYSDPKGQELSMVFQFEHIGLQYQEGQPKW
                     HYQKELNIAKLKEIFNKWQTELGVEDGWNSLFWNNHDLPRIVSIWGNDQEYREKSAKA
                     FAILLHLMRGTPYIYQGEEIGMTNYPFETLDQVEDIESLNYAREALEKGVPIEEIMDS
                     IRVIGRDNARTPMQWDESKNAGFSTGQPWLAVNPNYEMINVQEALANPDSIFYTYQKL
                     VQIRKENSWLVRADFELLDTADKVFAYIRKDGDRRFLVVANLSNEEQDLTVEGKVKSV
                     LIENTAAKEVLEKQVLAPWDAFCVELL"
     gene            2603..4087
                     /locus_tag="VU534_000968"
     CDS             2603..4087
                     /locus_tag="VU534_000968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008535024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HEU1513575.1"
                     /translation="MKKQAFSSEQYLNLQRDHILERINQFDGKLYLEFGGKMLEDFHA
                     ARVLPGYEPDNKIKLLQELKEQVEVVIAINASNIEHSKARGDLGISYDQEVLRLIDKF
                     NELGIFVGSVVITQYAGQPAADAFRNQLEKNGIDSYLHYPIKGYPTDMDHIISPEGMG
                     KNDYIKTSRNLIVVTAPGPGSGKLATCMSNMYHDQINGIKSGYAKFETFPVWNLPLHH
                     PVNLAYEAATADLDDVNMIDPFHLQTYGETTVNYNRDIEIFPVLKRMLERILGKSPYA
                     SPTDMGVNMVGFAITDDEAAVEASKQEIIRRYYQTVLDFKAEKVGEAAVKKIELLMND
                     LGITPADRKVAVVARQKAEETGGPALAFELPNGEIVTGKNSELFGPTAAALINAIKKS
                     ADIAKEVKLIEPEVVKPIQGLKIDHLGSRNPRLHSNEILIALAITATENPDAARAMEE
                     LGNLKGSEAHSTIILTDEDKNVLRKLGINVTFDPYYQYDRLYRK"
     gene            4182..4664
                     /locus_tag="VU534_000969"
     CDS             4182..4664
                     /locus_tag="VU534_000969"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HEU1513576.1"
                     /translation="MSKEVIVESFELDHTIVKAPYVRLIGEETGPKGDIISNYDIRLV
                     QPNEDSIPTAGLHTIEHLLAKLIRTRIDGMIDCSPFGCRTGFHMIMWGRHTSAKIAAV
                     IKDSLKEIAETTTWEDVPGTTIESCGNYKDHSLFSAKEWAKLILEQGISDDAFERHVI
                     "
     gene            complement(4960..7065)
                     /locus_tag="VU534_000970"
     CDS             complement(4960..7065)
                     /locus_tag="VU534_000970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001063405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEU1513577.1"
                     /translation="MNNNFNNFNNMDDLFNQLMGGMRGYSSENRRYLINGREVTPEEF
                     AHYRATGQLPGNAETDVQMPQQASGMKQGGVLAKLGRNLTAEAREGKLDPVIGRNKEI
                     QETSEILSRRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKNKEIISIDISGL
                     EAGTQYRGSFEENVQNLVNEVKEAGNIILFFDEIHQILGAGSTGGDSGSKGLADILKP
                     ALSRGELTVIGATTQDEYRNTILKNAALARRFNEVKVNAPSAENTFKILQGIRDLYQQ
                     HHNVILPDEVLKAAVDYSVQYIPQRSLPDKAIDLVDVTAAHLAAQHPVTDVHAVEREI
                     ETEKDKQEKAVEAEDFEAALNYKTRIAELERKIENHTEDMKVTASVNDVAESVERMTG
                     IPVSQMEASDIERLKDMAHRLQDKVIGQDKAVEVVARAIRRNRAGFDEGNRPIGNFLF
                     VGSTGVGKTELAKQLALDMFGTQDAIIRLDMSEYSDRTAVSKLIGTTAGYVGYDDNSN
                     TLTERVRRNPYSIILLDEIEKADPQVITLLLQVLDDGRLTDGQGNTVNFKNTVIIATS
                     NAGFGYEANLTEDADKPELMDRLKPFFRPEFLNRFNAVIEFSHLTKEDLSKIVDLMLA
                     EVNQTLAKKDIDLVVSQAAKDYITEEGYDEVMGVRPLRRVVEQEIRDKVTDFHLDHLD
                     AKHLEADMEDGVLVIREKV"
     gene            complement(7674..8654)
                     /locus_tag="VU534_000971"
     CDS             complement(7674..8654)
                     /locus_tag="VU534_000971"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000470804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HEU1513578.1"
                     /translation="MFISISAGIVTFLLTLVEIPAFIQFYRKAQITGQQMHEDVKQHQ
                     AKAGTPTMGGLVFLITSVLVAFFFALFSSQFSNNVGMILFILVLYGLVGFLDDFLKVF
                     RKINEGLNPKQKLALQLLGGVIFYLFYERGGDILSVFGYPVHLGFFYIFFALFWLVGF
                     SNAVNLTDGVDGLASISVVISLSAYGVIAYVQGQMDILLVILAMIGGLLGFFIFNHKP
                     AKVFMGDVGSLALGGMLAAISMALHQEWTLLIIGIVYVFETTSVMMQVSYFKLTGGKR
                     IFRMTPVHHHFELGGLSGKGNPWSEWKVDFFFWGVGLLASLLTLAILYLM"
     gene            complement(8656..10908)
                     /gene="pbpX"
                     /locus_tag="VU534_000972"
     CDS             complement(8656..10908)
                     /gene="pbpX"
                     /locus_tag="VU534_000972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2X"
                     /protein_id="HEU1513579.1"
                     /translation="MKWTKRVIRYATKNRKSPAENRRRVGKSLSLLSVFVFAIFLVNF
                     AVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGTIYDRNGVPIAEDATSYNVYAVIDE
                     NYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVREQLSQPNLKQVSFGAKGNGITY
                     ANMMSIKKELEAAEVKGIDFTTSPNRSYPNGQFASSFIGLAQLHENEDGSKSLLGTSG
                     MESSLNSILAGTDGIITYEKDRLGNIVPGTEQVSQRTMDGKDVYTTISSPLQSFMETQ
                     MDAFQEKVKGKYMTATLVSAKTGEILATTQRPTFDADTKEGITEDFVWRDILYQSNYE
                     PGSTMKVMMLAAAIDNNTFPGGEVFNSSELKIADATIRDWDVNEGLTGGRTMTFSQGF
                     AHSSNVGMTLLEQKMGDATWLDYLNRFKFGVPTRFGLTDEYAGQLPADNIVNIAQSSF
                     GQGISVTQTQMIRAFTAIANDGVMLEPKFISAIYDPNDQTARKSQKEIVGNPVSKDAA
                     SLTRTNMVLVGTDPVYGTMYNHSTGKPTVTVPGQNVALKSGTAQIADEKNGGYLVGLT
                     DYIFSAVSMSPAENPDFILYVTVQQPEHYSGIQLGEFANPILERASAMKDSLNLQTTA
                     KALEQVSQQSPYPMPSVKDISPGDLAEELRRNLVQPIVVGTGTKIKNSSAEEGKNLAP
                     NQQVLILSDKAEEVPDMYGWTKETAETLAKWLNIELEFQGSGSTVQKQDVRANTAIKD
                     IKKITLTLGD"
     gene            complement(10912..11229)
                     /gene="ftsL"
                     /locus_tag="VU534_000973"
     CDS             complement(10912..11229)
                     /gene="ftsL"
                     /locus_tag="VU534_000973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HEU1513580.1"
                     /translation="MAEKMEKTGQILQMQLKRFSRVEKAFYFSIAVTTLIVAISIIFM
                     QTKLLQVQNDLTKINAQIEEKKTELDDAKQEVNELLRAERLKEIANSHDLQLNNENIR
                     IAE"
     gene            complement(11241..12191)
                     /gene="rsmH"
                     /locus_tag="VU534_000974"
     CDS             complement(11241..12191)
                     /gene="rsmH"
                     /locus_tag="VU534_000974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HEU1513581.1"
                     /translation="MTKEFHHVTVLLHETIDMLDVKPDGIYVDATLGGAGHSEYLLSK
                     LSEKGHLYAFDQDQNAIDNAQKRLAPYIEKGMVTFIKDNFRHLQACLREAGVQEIDGI
                     CYDLGVSSPQLDQRERGFSYKKDAPLDMRMNQDASLTAYEVVNNYDYHDLVRIFFKYG
                     EDKFSKQIARKIEQAREVKPIETTTELAEIIKLVKPAKELKKKGHPAKQIFQAIRIEV
                     NDELGAADESIQQAMDMLALDGRISVITFHSLEDRLTKQLFKEASTVEVPKGLPFIPD
                     DLKPKMELVSRKPILPSAEELEANNRSHSAKLRVVRKIHK"
     gene            12357..12551
                     /locus_tag="VU534_000975"
     CDS             12357..12551
                     /locus_tag="VU534_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001082472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU1513582.1"
                     /translation="MNRVKEFRKELGISQLELAKDIGVSRQTINMIENDKYNPTLELC
                     LNLARSLQTDLNSLFWEEDF"
     gene            12567..13109
                     /locus_tag="VU534_000976"
     CDS             12567..13109
                     /locus_tag="VU534_000976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3278 domain-containing protein"
                     /protein_id="HEU1513583.1"
                     /translation="MKKETFTEKLIKRTYGISGPLDEYKRREADSIGNQVFIILFYLM
                     IFGNLIPLLLAYKYPQEVALIYPPLILVIALIASGYVTYQMKKTGITVIEPDMLNEKE
                     SKQLHYPGLKAGLFFGLWMFFITPLLRILIDEGQDYFHSLLTIRNGVSSILGSIFFGA
                     SIQFLISRRIAKTKKNQDED"
     gene            13120..13362
                     /locus_tag="VU534_000977"
     CDS             13120..13362
                     /locus_tag="VU534_000977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1513584.1"
                     /translation="MKKEKKQLRYPGLKAGSIYGTVIFFIIPLIDTLTSENPNFISSL
                     LNTKHIFKTILGAFFFGVMIHIVDSLRIARAKKDQD"
     gene            13373..13708
                     /locus_tag="VU534_000978"
     CDS             13373..13708
                     /locus_tag="VU534_000978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000838135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1513585.1"
                     /translation="MKSLARLLIIHVFISIFLFFALTSGAISHTVLLLLLLFLPALNK
                     GLEKIQSKRIPVLNAALFFLLISFPQLLTNPVQWKFSIFLVVTIISSLAYFYNFYQVV
                     KEVDQKQLI"
     gene            complement(13818..14819)
                     /locus_tag="VU534_000979"
     CDS             complement(13818..14819)
                     /locus_tag="VU534_000979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000412458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEU1513586.1"
                     /translation="MEKKLTIKDIAEMAQTSKTTVSFYLNGKYEKMSQETREKIEKVI
                     HETNYKPSIVARSLNSKRTKLIGVLIGDITNSFSNQIVKGIEDIASQNGYQVMIGNSN
                     YSQESEDRYIESMLLLGVDGFIIQPTSNFRKYSRIIDEKKKKMVFFDSQLYEHRTSWV
                     KTNNYDAVYDMTQSCIEKGYEHFLLITADTSRLSTRIERASGFVDALTDANMRHASLT
                     IEDKHTNLEQIKEFLQKEIDPDEKTLVFIPNCWALPLVFTVIKELNYNLPQVGLIGFD
                     NTEWTCFSSPSVSTLVQPSFEEGQQATKILIDQIEGRNQEERQQVLDCSVNWKESTF"
     gene            complement(14879..16780)
                     /locus_tag="VU534_000980"
     CDS             complement(14879..16780)
                     /locus_tag="VU534_000980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000657070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alginate lyase family protein"
                     /protein_id="HEU1513587.1"
                     /translation="MKEERRQFFERVDGNQCRDYILSHCSKDYEKVKSSLERLMDNRF
                     MFDSPWDMEPCSKIHQIQPMVWDQVFEDDPEWSYMLNRQEYLLQFMIGYLVEGDKDYI
                     QKCKFFLFDWIEQVREFSPQSLMTRTLDTGIRSFTWLKLLLLLLKFDLLEEKELEKIL
                     VSLEKQIDFMKSYYRAKYTLSNWGILQTIPMLAIYHFFSDKMDLEEAYHFASEELKQQ
                     IETQILGDGSQFEQSILYHVEVYKALLDLCLLLPDLQDSYQELLEKMATYIQMMTGLD
                     GRTLAFGDSDSTETTEILSLSAVVLNQEDLLNGLDVKVDLLSLLFLGREKVKRLQEFE
                     KRAWQPKSMIFEDSGHVCIKDEHRYLFFKNGPLGSAHSHSDENSFCLQYQGQPIFIDA
                     GRYSYREIYERYLLKSAWSHSTCIVDGKAPERITGSWEYEYYPHSLFCHHKEREGVHY
                     IEGAYWSAEPDLPYLHRRKILMLVEDVWLLVDDIRCQGQHEVLTQFILDKDVTYQDGK
                     INQLRLWSEVDFDLEDTIISPKYNELERSSKLTKRQFFENQMLDYTIIAHESFEIIRH
                     SVYQTDDREVENALAFEVKNDETDKLILLLSEDIGVGEKLCLVDGTKMRGKCLVYDKI
                     NERMIRLQC"
     gene            complement(16802..17095)
                     /locus_tag="VU534_000981"
     CDS             complement(16802..17095)
                     /locus_tag="VU534_000981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000381741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HEU1513588.1"
                     /translation="MDTTLFYGIVIVLAVSPLLLSSFHSIRQQKLLRKQMEQRQEYLA
                     SLTFGDEVLLLSGIHGKIISIQDDLVSLQIAKGVVIHVEKESVMGKTKELLFK"
     gene            complement(17095..17913)
                     /locus_tag="VU534_000982"
     CDS             complement(17095..17913)
                     /locus_tag="VU534_000982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEU1513589.1"
                     /translation="MTGSNKLTKRDYLKTSLRAFFCQNGFNYSNYQGLGYANVMYPAL
                     KKHYGEDQEGFYQALEENCEFYNTNPHFLPFITSLHLVMLENGRPAKETRSIKMALMG
                     PLAGIGDSLSQFCLAPLFSTIAASFAQEGLVVGPILFFLAMNTILTAIKLSTGLYGYK
                     LGTTVIDKLSEQMATISRIANIIGVTVIAGLAATSVKIMVPITFAAGEVKADAKQSIV
                     SIQGMLDKVAPALLPALFTLLVYYLIKEKKWTTYKLVILTVIIGIIGSWLKIIA"
     gene            complement(17900..18679)
                     /locus_tag="VU534_000983"
     CDS             complement(17900..18679)
                     /locus_tag="VU534_000983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000026606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HEU1513590.1"
                     /translation="MSINVFQAILIGLWTAFCFSGMLLGIYTNRCIVLSFGVGIILGD
                     LPTALAMGAIGELAYMGFGVGAGGTVPPNPIGPGIFGTLMAITSAGKVSPEAALALST
                     PIAVAIQFLQTFAYTVRAGAPETAMKHLKNHNLKKFKFTLNATIWLFAFIGFTLGCLG
                     ALSMDTLLKLVDYIPPVLLTGLTVAGKMLPAIGFAMILSVMAKKELIPFVLLGYVCAA
                     YLNIPTIGIAIVGTIFALIEFYNKPKTADHVVEEEAHDDWI"
     gene            complement(18694..19185)
                     /locus_tag="VU534_000984"
     CDS             complement(18694..19185)
                     /locus_tag="VU534_000984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000178618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HEU1513591.1"
                     /translation="MTMPNIIMTRIDERLIHGQGQLWVKYLGCNTVIVANDEVSTDKM
                     QQTLMKTVVPDSVAMRFFPLQKVIDIIHKANPAQTIFIVVKDVKDALTLVEGGVTIKE
                     INIGNIHNAPGKEQVTRSIFLGEEDKAALKELSQTHQVTFNTKTTPTGNDGAVQVNIM
                     DYI"
     gene            complement(19196..20386)
                     /locus_tag="VU534_000985"
     CDS             complement(19196..20386)
                     /locus_tag="VU534_000985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003074342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="unsaturated chondroitin disaccharide hydrolase"
                     /protein_id="HEU1513592.1"
                     /translation="MIKKVTIEKIKSPERFLEVPLLTKEEVGQAIDKVIRQLELNLDY
                     FKEDFPTPATFDNVYPIMDNTEWTNGFWTGELWLAYEYSQQDAFKNIAHKNVLSFLDR
                     VNKRVELDHHDLGFLYTPSCMAEYKINGDGEAREATLKAADKLIERYQEKGGFIQAWG
                     DLGKKEHYRLIIDCLLNIQLLFFAYQETGDQKYYDIAESHFYASANNVIRDDASSFHT
                     FYFDPETGQPFKGVTRQGYSDDSCWARGQSWGVYGIPLTYRHLKDESCFDLFKGVTNY
                     FLNRLPKDHVSYWDLIFNDGSDQSRDSSATAIAVCGIHEMLKHLPEVDADKDIYKHAM
                     HAMLRSLIEHYANDQFTPGGTSLLHGVYSWHSGKGVDEGNIWGDYYYLEALIRFYKDW
                     NLYW"
     gene            complement(20398..20832)
                     /locus_tag="VU534_000986"
     CDS             complement(20398..20832)
                     /locus_tag="VU534_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEU1513593.1"
                     /translation="MKIVLVGHGHFATGIYSSLQLIAGNQENVEAIDFVEGMSADELK
                     QKILLAISNEEEVLILSDLLGGSPFKVSSTIMGENPAKTMNVLSGLNLAMLMEAVFAR
                     MAHSFDEVVNKSVVAAQGGVVNGKELFSTDAEEEEEDFESGI"
     gene            21103..21918
                     /locus_tag="VU534_000987"
     CDS             21103..21918
                     /locus_tag="VU534_000987"
                     /EC_number="1.1.1.69"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate 5-dehydrogenase"
                     /protein_id="HEU1513594.1"
                     /translation="MTNTSFSIEQFSLKGKIALITGASYGIGFAIAKSYAEAGATIVF
                     NDINQDLVNKGIEAYREVGIQAHGYVCDVTDEDGIQAMVKQIEQEVGVIDILVNNAGI
                     IRRVPMCEMSAADFRKVIDIDLNAPFIVSKAVIPSMIKKGHGKIINICSMMSELGRET
                     VSAYAAAKGGLKMLTRNIASEYGGANIQCNGIGPGYIATPQTAPLRELQEDGSRHPFD
                     QFIIAKTPAARWGNTEDLMGPAVFLASDASNFVNGHILYVDGGILAYIGKQPE"
     gene            21937..22578
                     /locus_tag="VU534_000988"
     CDS             21937..22578
                     /locus_tag="VU534_000988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RpiB/LacA/LacB family sugar-phosphate isomerase"
                     /protein_id="HEU1513595.1"
                     /translation="MKIALINENSQASKNHIIYDSLKEATDKKGYQLFNYGMRGEEGE
                     SQLTYVQNGLMAAILLNTKAVDFVVTGCGTGVGAMLALNSFPGVVCGLAVDPTDAYLY
                     SQINGGNALSIPYAKGFGWGAELTLKLMFERLFAEEMGGGYPRERVIPEQRNARILNE
                     VKQITHNDLMTILKIIDQDFLKDTISGKYFQEYFFENCQDDEVAAYLKEVLAK"
     gene            22609..23610
                     /locus_tag="VU534_000989"
     CDS             22609..23610
                     /locus_tag="VU534_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HEU1513596.1"
                     /translation="MTKILLFGEPLIRISPLDATSIGDHVASSTYFGGSEINIACNLQ
                     ALGISTKVFTALPANEIGDRFLTFLKQHQIDTSSICRLGDRIGLYYLENGFGCRQSEV
                     FYDRKHTSISQIRPNMLDMDSLFQGISHFHFSGITVAIGQEVRAILLLLLEEAKRRGI
                     VVSMDLNLRTKMISVLEAKYEFSKFARFTDYCFGIDPLMIDDQNLEMFPRDSASLEEV
                     ENRMRLLKEAYGFKAIFHTLRSSDEQDKNVYQAYALEELFEESVQLKTAVYQRIGSGD
                     AFISGALYQLLHHSSLKTTIDFAVASATLKCTLPGDHLSTSSTSIENLLANAQDIIR"
     gene            23620..24249
                     /locus_tag="VU534_000990"
     CDS             23620..24249
                     /locus_tag="VU534_000990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HEU1513597.1"
                     /translation="MTKSDTIIELKKQKIVAVIRGNTKEEGLQASIACIKGGIKAIEI
                     AYTNQYAGQIIKELVDLYQDDQSVCIGAGTVLDAVTARDAILAGANYVVSPSFHAETA
                     KMCNLYSTPYIPGCITLTEITTALEAGSEIIKLFPGSTLSPAYISAVKAPIPQVSVMV
                     TGGVGLNNIPQWFAAGADAVGIGGELNKLASQGNFDRISEIAQQYITLR"
     gene            complement(24628..25013)
                     /gene="tnpA"
                     /locus_tag="VU534_000991"
                     /pseudo
     CDS             complement(24628..25013)
                     /gene="tnpA"
                     /locus_tag="VU534_000991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005816675.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
     gene            complement(25397..28597)
                     /locus_tag="VU534_000992"
     CDS             complement(25397..28597)
                     /locus_tag="VU534_000992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001193686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored hyaluronate lyase"
                     /protein_id="HEU1513598.1"
                     /translation="MQTKTKKLIVSLSSLVLSGFLLNHYMTIGAEETTTNTIQQSQKE
                     VQYQQRDTKNLVENGDFGQTEDGSSPWTGSKAQGWSAWVDQKNSADASTRVIEAKDGA
                     ITISSHEKLRAALHRMVPIEAKKKYKLRFKIKTDNKIGIAKVRIIEESGKDKRLWNSA
                     TTSGTKDWQTIEADYSPTLDVDKIKLELFYETGTGTVSFKDIELVEVADQLSEDSQTD
                     KQLEEKIDLPIGKKHVFSLADYTYKVENPDVASVKNGILEPLKEGTTNVIVSKDGKEV
                     KKIPLKILASVKDAYTDRLDDWNGIIAGNQYYDSKNEQMAKLNQELEGKVADSLSSIS
                     SQADRTYLWEKFSNYKTSANLTATYRKLEEMAKQVTNPSSRYYQDETVVRTVRDSMEW
                     MHKHVYNSEKSIVGNWWDYEIGTPRAINNTLSLMKEYFSDEEIKKYTDVIEKFVPDPE
                     HFRKTTDNPFKALGGNLVDMGRVKVIAGLLRKDDQEISSTIRSIEQVFKLVDQGEGFY
                     QDGSYIDHTNVAYTGAYGNVLIDGLSQLLPVIQKTKNPIDKDKMQTMYHWIDKSFAPL
                     LVNGELMDMSRGRSISRANSEGHVAAVEVLRGIHRIADMSEGETKQCLQSLVKTIVQS
                     DSYYDVFKNLKTYKDISLMQSLLSDAGVASVPRPSYLSAFNKMDKTAMYNAEKGFGFG
                     LSLFSSRTLNYEHMNKENKRGWYTSDGMFYLYNGDLSHYSDGYWPTVNPYKMPGTTET
                     DAKRADSDTGKVLPSAFVGTSKLDDANATATMDFTNWNQTLTAHKSWFMLKDKIAFLG
                     SNIQNTSTDTAATTIDQRKLESGNPYKVYVNDKEASLTEQEKDYPETQSVFLESFDSK
                     KNIGYFFFKKSSISMSKALQKGAWKDINEGQSDKEVENEFLTISQAHKQNRDSYGYML
                     IPNVDRATFNQMIKELESSLIENNETLQSVYDAKQGVWGIVKYDDSVSTISNQFQVLK
                     RGVYTIRKEGDEYKIAYYNPETQESAPDQEVFKKLEQAAQPQVQNSKEKEKSEEEKNH
                     SDQKNLPQTGEGQSILASLGFLLLGAFYLFRRGKNN"
     gene            28820..29296
                     /locus_tag="VU534_000993"
     CDS             28820..29296
                     /locus_tag="VU534_000993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HEU1513599.1"
                     /translation="MTSLYDFSVLNQNNQATPLDSYRGKVLLIVNTATGCGLTPQYQG
                     LQELYERYQDQGFEILDFPCNQFMGQAPGSAEEINAFCSLHFQTTFPRFAKIKVNGKE
                     ADPLYVWLQDQKSGPLGKRVEWNFAKFLIGRDGQVFERFSSKTDPKQIEEAIQTLL"
     gene            complement(29518..31731)
                     /locus_tag="VU534_000994"
     CDS             complement(29518..31731)
                     /locus_tag="VU534_000994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000688702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 31 protein"
                     /protein_id="HEU1513600.1"
                     /translation="MKIFKGEFYRISVLTDKLVRLEYSQTGSFEDRTTQLIYNRDFGQ
                     ISLDYIETSNVLDIMTDYFHLHFNKGEFNAENLFIELKGNFAVYGSRWYFGESIETLK
                     GTARTLDKADGAISLEDGIISRNGIALLDDSQGFIWDEQSGYIERENQIDLYFFAYGH
                     DYRGAIRDFYHLTGSTPLLPRYALGNWWSRYWPYTSDEYLDLIDRFETEKIPLSIGVL
                     DMDWHITDIPARFGSGWTGYSWNRNLIPNPEQLLQQLHDRKLKLSLNVHPADGIRAYE
                     EAYPQIAKRLGLNVELEEPAIFDFFNPSFREAYFKDVHYELEKQGVDFWWIDWQQGTQ
                     GMLDPLWLLNHYHYQDSCKNAEGGLILSRYAGPGSHRYPVGFSGDTIISWNSLRFQPY
                     FTATASNIGYSWWSHDIGGHMLGDYDEELQTRWLQFGVFSPITRLHSSRSPFNSKEPW
                     FFSETTSKIMKKYLRLRHQMIPYLYTMNVQTHEEGAPLISPIYYFYPENDESYNVPNQ
                     YFFGTELMVAPIVEKMDLTFQSAKVDVWFPEGEWYDFFSEKKYTGGVKLSVYRDISTT
                     PVFAKSGAIIPLVGSEIGMGVDLPEVVDWYVFPGKQHSFEMLEDQNGQRYKTRLSIDW
                     EMGMVELALQGDSSIVPSNRKHRIHFKGTNVSIIELPNKNDTAKFEWKDNKRTSLNDE
                     VFRLLKTASLPYELKDRLLNQFINAKNSHDLMNILHHQDKELRGRLLEMIFTSQN"
     gene            complement(32132..32308)
                     /locus_tag="VU534_000995"
     CDS             complement(32132..32308)
                     /locus_tag="VU534_000995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1513601.1"
                     /translation="MFLDIDKEKMTIMGIAFENRSVFKSVWYALSTNMIEGWRPTVSD
                     VEKLRDEALALGMT"
     gene            complement(32687..34033)
                     /gene="celB"
                     /locus_tag="VU534_000996"
     CDS             complement(32687..34033)
                     /gene="celB"
                     /locus_tag="VU534_000996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HEU1513602.1"
                     /translation="MDQQNGLFGFLENHVMGPMGKLAQFKVVRAITAAGMAAVPFTIV
                     GSMFLVFSILPQAFSFWPIVADIFSASFDKFTSLYMVANYATMGSLSLYFVLSLAYEL
                     TKIYAEEEELNMNPLNGALLALMAFVMTVPQIIFDGGMMKTVTSLKEGAVIADGWAMG
                     NVVARFGTTGIFTAIIMAIVTVLIYRMCVKHNWVIKMPEAVPEGVSRGFTALVPGFVV
                     AFVVIFINGLLVAMGTDIFKVIAIPFGFVSNLTNSWIGLMIIYLLTQLLWIVGIHGAN
                     IVFAFVSPIALANMAENAAGGHFAVAGEFSNMFVIAGGSGATLGLCLYIAFASKSEQL
                     KAIGRASVVPALFNINEPLIFGLPIIYNPALAIPFILAPMVTATIYYVANSLNFIKPI
                     IAQVPWPTPVGIGAFLGTADLRAVLVALVCAFAAFLVYLPFIRVYDQKLVKEEQGI"
     gene            complement(34113..34619)
                     /locus_tag="VU534_000997"
     CDS             complement(34113..34619)
                     /locus_tag="VU534_000997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1513603.1"
                     /translation="MDKKERQKIEQQRREMALTNTFFNRYLLLRYSIALFFFGNIYWL
                     LSQFISPSPIIIFPIMLIVFSILATVEQFKLYGNRKEKLGITLMFVRIQMLISIGLLV
                     LTWTSWFKNLFPIFENNQVARLFVFVVLLLGLVLSLLDIRRIKKIYKRTDKAYQQFVQ
                     LEKNSLSL"
     gene            complement(34650..34964)
                     /locus_tag="VU534_000998"
     CDS             complement(34650..34964)
                     /locus_tag="VU534_000998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001070943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIA"
                     /protein_id="HEU1513604.1"
                     /translation="MNQEELQVAAFEIILHSGNARSEIHEAFAKMREGSFDDAESKLN
                     QSNEIILEAHHAQTKLLQEYASGVEIKIEIIMVHAQDHLMTTMTLLEVAKEMLALYKK
                     VN"
     gene            complement(34974..36953)
                     /locus_tag="VU534_000999"
                     /pseudo
     CDS             complement(34974..36953)
                     /locus_tag="VU534_000999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001101767.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
     gene            complement(37071..37385)
                     /locus_tag="VU534_001000"
     CDS             complement(37071..37385)
                     /locus_tag="VU534_001000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003037418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIB"
                     /protein_id="HEU1513605.1"
                     /translation="MAKALIICAAGMSSSLMAQKTTEFLKGKGKDIVVDAISATEGGK
                     AIAAAAFDLYLVSPQTKMYFKQFEEAGSKAGKPVVQIPPQAYIPIPMGIEKMANLILE
                     NI"
     gene            complement(37515..37754)
                     /locus_tag="VU534_001001"
     CDS             complement(37515..37754)
                     /locus_tag="VU534_001001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000580385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SemiSWEET family sugar transporter"
                     /protein_id="HEU1513606.1"
                     /translation="MIGSIAAILTTFAFLPQVFRVVKTKDTGSIALGMYVMQVIGIAL
                     WLAHGIRIGDLPLILANSVSFLLSGIILFYKLKYK"
     gene            complement(37806..39242)
                     /locus_tag="VU534_001002"
     CDS             complement(37806..39242)
                     /locus_tag="VU534_001002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HEU1513607.1"
                     /translation="MTTFKDGFLWGGAVAAHQLEGGWQEGGKGISVADVMTAGRHGVA
                     REITLGVLEGKYYPNHEAIDFYHRYKEDIALFAEMGFKCFRTSIAWTRIFPKGDELEP
                     NEEGLQFYDNLFDECLKNGIEPVITLSHFEMPYHLVTEYGGWKNRKLIDFFARFAEVV
                     FKRYKDKVKYWMTFNEINNQANYQEDFAPFTNSGIVYEEGDNREAIMYQAAHYELVAS
                     ARAVKIGHEINPDFQIGCMIAMCPIYPVTCNPKDILMAMKAMQKRYYFADVHVLGKYP
                     EHIFKYWERKGISVDFTAQDKEDLLGGTVDYIGFSYYMSFAIDSHRENNPYFDYLETE
                     DLVKNNYVKASEWEWQIDPEGLRYALNWFTDHYHLPLFIVENGFGAIDQVAADGMVHD
                     DYRIEYLGAHIREMKKAVVEDGVDLMGYTPWGCIDLVSAGTGEMRKRYGFIYVDKDDN
                     GKGSYNRSPKKSFGWYKEVISSNGESVE"
     gene            complement(39432..39770)
                     /locus_tag="VU534_001003"
     CDS             complement(39432..39770)
                     /locus_tag="VU534_001003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000176371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antibiotic biosynthesis monooxygenase"
                     /protein_id="HEU1513608.1"
                     /translation="MTLTIHVYYKGDGDSAIKFAREMLDSGLVKEIRNQKGNLKYEYF
                     LPIEKEGTILLIDQWINQETLDKHYQSKTMQKILDLRKKYHLQMQVERYIEDDSGMPE
                     SDKSFIDTGN"
BASE COUNT        12063 a         8678 c         6726 g        12484 t
ORIGIN      
        1 aacaaaaccc agaaaaagta gccttatttc ttaagaattt taatagttta aagcacctag
       61 cacctgttta gattgatgaa acaggattcg atacttattt ttatcgagaa tatggtcgct
      121 cattaaaagg tcagttaaga agaggcaaag tatctggaag aagatatcag aggatttctt
      181 tggttgcagg tctaacaaat ggtgagttaa tcgctccaat aacttacgaa gagacgatga
      241 cgagcgactt ttttgaagct tggtttcaga aatttctctt accaacatta aacacaccat
      301 cggttattat tatggataat gcaagattcc atagaatggg taagttagaa ctcttgtgtg
      361 aagagtttgg gtataaactt ttacctcttc ctccctactc acctgagtac aatcctattg
      421 agaaaacatg ggctcatatc aaaaagcacc tcaaaaaggt attaccaagt tgcaatacct
      481 tttatgaggc tcttttgtct tgttcttgtt tcaattgact atattatcag cgtaatagtc
      541 taatagatag ttaaatgtag ttggatttcc actaaaggtt gatgagtaag tttttgtatc
      601 tgaacctgat tggccgcaag cagctaaaag caaagcagat gcaaaagtca ggcctgcact
      661 aaggacacgc ttctttatgt tcatcttctt tctccttaat agtgggaatt tgtaaagtta
      721 attgaatttc aagaatgaaa gtttataaac tttggttata aaaaacaaag gatttctgtc
      781 ttttatacag tcctcccttg tttttatacg atttcaattt taaatttttc tgcaaaaaat
      841 atttatagta attccacaca gaaagcatcc catggagcca agacctgttt ttcaagtact
      901 tctttagccg cagtgttttc aatcaagaca gatttgactt ttccttctac tgtcaagtct
      961 tgctcttcat tggacaagtt agccacaact aggaagcgac ggtcgccatc cttacgtata
     1021 taagcaaaga ccttatcagc cgtatcaagc aattcaaagt cagctcgaac tagccagcta
     1081 ttctccttgc gaatttggac cagtttctga taggtataga aaatagaatc tggatttgcc
     1141 agcgcttctt ggacattgat catctcgtaa tttggattaa ccgccaacca aggttgacct
     1201 gttgagaaac cagcgttttt gctctcgtcc cattgcatag gggtacgggc attgtcacgt
     1261 ccaataacac ggatactgtc catgatttct tcaatcggaa cacctttttc aagagcctca
     1321 cgcgcatagt tgagagattc aatatcttct acttgatcca gtgtttcaaa cggatagttg
     1381 gtcatcccaa tctcctcacc ttggtagata taaggagttc ctctcatgag atgaagtaag
     1441 attgcaaagg ctttggcaga tttttcgcgg tattcttggt catttcccca gattgagaca
     1501 atacgaggga ggtcatggtt gttccagaag agggaattcc agccgtcctc aactcctaac
     1561 tctgtctgcc atttgttgaa gatttctttt aacttagcga tattcagctc tttttgatag
     1621 tgccatttag gctgaccttc ctgatactga agaccgatat gttcaaactg gaagaccata
     1681 gacaattctt gcccctttgg atcagagtag aacttggcaa tctctggagt tgctccccaa
     1741 gtctccccta ctgtcaagag atccttatct ccaaaggtcg cctgattcat ttccttgaga
     1801 tagggatgga gcataggacc attattgact accttctcgt caggaatttt gccaatcatg
     1861 tcaataacat ccatacggaa accaccaata cctttatcaa tccagaagtt catcatctca
     1921 taaattttct ggcgaagttt ttcattttcc cagttgagat ccggctgttt cttgctgaaa
     1981 aagtggagat agtattgacc tgacttttca tcgtattccc aagcagaccc actaaagata
     2041 gaatctaggt cattgggttc atcgcgccag atatagtagt ctcgctcagg gctgtcagta
     2101 ttttcacagg cttcgacaaa ccaagcatgt tcatctgagg tatgattgac caccaagtcc
     2161 atgatgatac gaatgtcacg cttcttagct tctgcaatca gctgatccat gtcctccatg
     2221 gttccaaaaa tagccgcaat cgcttgataa tcagcaatat catagccatt atcatccata
     2281 gggctgtcat aaacgggaga aagccaaatt gctgtgattc ctagcttagc tagatagtcc
     2341 aacttactgg taatacctgg caaatcacca actccatctc cattactatc cataaaactc
     2401 tttggataga cttgatagac tacggcattg tgccaccatt tttcttgcat ctgtttacct
     2461 cattattttc ataatctata gtctatgata gcacttttta aaattttgtg caagcgtttg
     2521 cttaatcttt ttaatttctt ttttagctcc gtagtttcct aacttccaat tttttattat
     2581 aatagagtcc agaggtaaaa aaatgaaaaa acaagctttt agttctgaac aatatttgaa
     2641 tttacaacgc gaccatattt tggagcgcat taaccaattt gacggcaagc tctacttaga
     2701 gtttggcggt aaaatgttag aagatttcca cgctgctcgt gtccttcctg gttatgaacc
     2761 tgacaacaaa atcaagctct tgcaagaatt gaaagagcag gttgaggttg tgattgccat
     2821 taatgctagc aacattgaac attccaaagc acgtggcgac ttaggcattt cttatgacca
     2881 agaagttctt cgtttgattg ataaattcaa tgaattaggg atttttgttg gttccgttgt
     2941 cattacacaa tacgctggcc aacccgctgc agatgccttc cgcaatcaac ttgagaaaaa
     3001 cggaattgat tcttatcttc attatccaat caaaggatat ccgacggata tggatcacat
     3061 catttcccca gaaggcatgg gcaaaaacga ctacatcaaa accagtcgca acttgattgt
     3121 cgtaaccgct cctggacctg gttctggaaa attggcaacg tgtatgtcca atatgtacca
     3181 cgaccaaatc aatggcatca aatctggcta cgctaaattt gaaaccttcc ctgtttggaa
     3241 tcttcccctt catcatccag ttaacttggc ttatgaagct gccacagctg accttgatga
     3301 tgtcaacatg attgacccct tccatcttca aacctatgga gaaaccactg tcaactacaa
     3361 ccgtgatatc gaaatcttcc cagtgctcaa acgcatgttg gaacgtattc tcggaaaatc
     3421 accatacgct tcaccgacag atatgggtgt caacatggtt ggtttcgcta ttacagatga
     3481 cgaggccgct gtcgaagctt ctaaacaaga aatcatccgc cgttactatc aaacagttct
     3541 tgacttcaaa gctgaaaaag ttggcgaagc tgccgtcaag aaaattgagt tgctcatgaa
     3601 cgacctcggt atcacacctg cagaccgtaa ggttgctgtc gttgcgcgcc aaaaagcaga
     3661 agaaactggt ggaccagccc tagcctttga attgccaaat ggggaaatcg tcactggtaa
     3721 gaactcagaa ctctttggtc ctacagccgc tgccttgatc aacgccatca aaaaatcagc
     3781 tgacatcgct aaagaagtaa aactaatcga gcctgaagtt gttaagccaa tccaaggtct
     3841 taaaatcgat catctcggta gccgcaatcc acgccttcat tcaaatgaaa tcctgattgc
     3901 acttgctatc acagctacag aaaatcctga tgctgcccgc gctatggaag aactcggcaa
     3961 cctcaaagga agcgaagccc actcaaccat catcttgact gatgaagaca agaatgtcct
     4021 tcgtaaactg ggtatcaacg taacctttga cccatactac caatacgacc gcttatatcg
     4081 taagtaaaga tttcaacctc tccagcctcg gagaggtttt ctctctgtct caggagcaac
     4141 ctttatgata taatgagaga agaaaactga aaggatttac catgtcaaaa gaagttattg
     4201 tcgaaagttt tgaacttgac cacaccattg tcaaagcacc ctatgttcgc ttgattgggg
     4261 aagaaacagg accaaaagga gacatcatct ccaattatga tattcgcttg gtgcaaccaa
     4321 acgaagactc tatccctact gccggccttc acactatcga gcacctctta gccaaactca
     4381 tccgtacccg cattgacggc atgattgact gttcaccatt tggttgccgc acaggcttcc
     4441 acatgattat gtggggacgt cacaccagtg ctaaaatcgc agctgttatc aaggattcgc
     4501 tcaaggaaat cgctgaaact actacttggg aagatgtccc agggacaacc atcgaatctt
     4561 gcggaaacta caaggaccac agcctcttct ctgctaaaga atgggcaaaa ctcatcttgg
     4621 aacaagggat ttcagatgat gcctttgaac gtcatgtgat ttaaaatcga gtaggggata
     4681 atctctagcc cctctcacac caccgtacgt accattcggc atacggcggt tcaactaact
     4741 tttaacgcat gtcgttcaag gtaataatcc aaacacgaaa ccagtccacg tttttccagg
     4801 actggttttg atatagcacg tttaagtacc gacttctgag ctactatagt atattgaaac
     4861 tagaataata cacttctact atacgacatg cctgtcgtac ctaaaaagga accagttttt
     4921 ttcagctggc tccttctttt ttatcctcaa aattctgtct tagactttct cacgaataac
     4981 caaaacgcca tcttccatat ctgcttccag atgtttagca tctaaatgat ccaagtggaa
     5041 gtctgtcacc ttatcacgaa tttcttgttc aaccacgcga cggagaggac gaacccccat
     5101 gacttcgtcg taaccttctt ctgtgatata atctttagcc gcttgactga ctaccaagtc
     5161 aatgtctttc ttagccaagg tttggttaac ttcagccaac atcaaatcta caatcttaga
     5221 aaggtcttcc ttagtcaagt gtgagaactc gatgactgca ttaaagcggt tgaggaattc
     5281 tggacggaag aagggtttca aacggtccat caattctggt ttatccgcat cttctgtcaa
     5341 gttggcttca tagccaaatc cagcatttga ggtcgcaata atgacagtgt tcttgaagtt
     5401 tactgtattt ccttgaccat ctgtcaaacg accatcatct agaacttgga ggagaagggt
     5461 aataacttga gggtcagcct tttcaatttc atccaagaga atgatagagt atggattgcg
     5521 acgaacacgt tctgttaagg tattgctatt gtcatcataa cccacatagc ctgctgttgt
     5581 accaattagc ttagaaacag ctgtgcggtc actgtattca gacatatcta aacggataat
     5641 cgcatcctgg gttccaaaca tatcgagtgc caattgctta gcaagctccg tcttaccaac
     5701 cccagtagac cctacaaaga ggaagttgcc gattgggcga tttccttcat caaaaccagc
     5761 acggttacga cggatagcac gagctacaac ttctacggcc ttatcttgac caatcacctt
     5821 gtcttgcaag cgatgagcca tatctttcaa acgttcgata tctgaagctt ccatttgcga
     5881 tactgggata cctgtcattc gttccacaga ttcagccaca tcgttgacac ttgcagtcac
     5941 tttcatatct tctgtgtggt tttcgatttt cctttccaat tctgcaatgc gtgttttata
     6001 gtttagagct gcttcaaaat cttctgcttc aactgctttt tcttgcttgt ctttttccgt
     6061 ttcgatttct cgttcaacag catgcacatc tgttactgga tgttgagccg ccaagtgagc
     6121 agccgttaca tcgacaaggt caatagcctt atctggcaag ctacgttgag gaatgtattg
     6181 aacagaataa tccaccgctg ctttcaagac ttcgtctggc aagatgacat tgtggtgttg
     6241 ttgatagagg tcacgaattc cttgaagaat tttaaaagta ttctctgccg aaggagcatt
     6301 gaccttcact tcgttgaaac gacgagcaag agcagcattc ttcaagatgg tgttacggta
     6361 ttcgtcttga gttgttgccc caatcactgt caattctcca cgagagagag ctggcttgag
     6421 aatatccgca agtcctttag aaccactgtc tccaccagtg ctaccagcac caagaatttg
     6481 gtgaatttca tcaaagaaga ggataatatt ccctgcttct ttcacttcat tgactaagtt
     6541 ttggacattt tcttcaaagc taccacggta ttgagtacca gcctcaagac ctgagatatc
     6601 aatagaaata atttccttgt tcttgatagc agcaggaaca tctccgttca caatggcttg
     6661 cgctagacct tcgacaactg ctgtcttacc aacacctgca tctccgacca aaacaggatt
     6721 gttcttggtg cggcgtgaga ggatttcaga tgtttcttga atttccttgt ttcgtccgat
     6781 aacaggatcc aacttgccct cacgcgcttc tgctgttaag tttcgaccta gttttgcaag
     6841 gacaccgcct tgtttcatac ctgatgcctg ttgtggcatt tgcacatcag tttctgcatt
     6901 tcctggtaat tgaccagtcg cacgatagtg agcaaattcc tcaggtgtga cttcgcgtcc
     6961 attaattaag taacggcgat tttcagaact gtatcctcgc ataccaccca tcaattggtt
     7021 aaataaatca tccatgttat taaaattatt aaagttgtta ttcatattct ttacctcttt
     7081 ttgtttactt agttatgatt actgatattg actatctttg accattgttt taaaaaattt
     7141 agactagcta gatcgctacc ctacgtacta tttctggttt ttctttttca agcaggagta
     7201 gactatcttt acttctgaag atttctagat gaaacataga cccacctctt tctattttac
     7261 tttaaataag tgttctagta aggctttcat ttaccttacg ttcataatat actacattgg
     7321 tcagaaaagg tcaagagttt tgactttaac tgaccaatat ttttttacac tcttcgaaaa
     7381 cctcttcaaa ccacatcagc ttctccttat ctacaacctc aaaaccgtgt tttgagctga
     7441 cttcgtcagt tctatcaacc atctcaaaac tgtatattaa aacgaaataa gaacaggaca
     7501 aatcaatcag gacagtcaaa tcgatttcta acaatatttt agaagtagat gtgtactatt
     7561 ctagtttcaa tctactatat tttgagcagc ctaaagttag ctttctagtt tgttctttga
     7621 ttttcattgt gtatttaaac acaaaaacac cctgaaacat cagggtgcca ttcttacatc
     7681 aaatataaaa ttgctagggt caggagactt gctagaagtc ccactcccca aaagaagaag
     7741 tcaaccttcc actcgctcca aggatttcct ttaccagaca atcccccaag ctcaaaatgg
     7801 tgatgtacag gcgtcatacg gaaaatacgt ttaccacctg tcagtttgaa ataactgact
     7861 tgcatcataa cagaagttgt ttcaaaaaca tacacaattc cgataatcaa gagagtccat
     7921 tcttggtgga gagccataga gatagctgcc agcatcccac ctagggccaa acttcccaca
     7981 tcacccataa agaccttggc aggcttatgg ttaaagatga agaaaccgag caaaccacca
     8041 atcatggcaa gaatcactag aagaatatcc atctgacctt gcacataggc aataactcca
     8101 taggcagaca aactaatcac aacggaaata ctagctaaac cgtcaacacc gtctgtcaag
     8161 tttactgcgt ttgaaaaacc gactagccag aaaagagcga agaaaatata gaaaaatccc
     8221 aaatgaactg gataaccaaa gacagacagg atatcgccac cgcgctcata gaaaagatag
     8281 aagataactc cacctagaag ctgaagagct aatttttgct taggattaag cccctcattg
     8341 attttacgaa agaccttgag aaagtcatct aaaaatccga ccaagccata caagaccaag
     8401 atgaacaaaa tcattcccac attattgctg aattggctac taaatagggc gaaaaagaaa
     8461 gcaaccaaaa cagaagtaat caagaaaacc aaacctccca ttgtaggagt cccagctttt
     8521 gcctgatgct gtttgacatc ctcatgcatc tgctggcctg taatttgcgc ctttctataa
     8581 aattggataa aggccggaat ttctactaaa gttagtaaaa atgtcacaat tccagcactg
     8641 atggaaataa acatattagt ctcctaaagt taatgtaatt tttttaatgt ccttgatagc
     8701 tgtgttagca cgaacatctt gcttctgcac agtagagccc gaaccttgaa attcaagttc
     8761 tatattgagc cacttagcaa gggtctcagc agtctccttt gtccaaccat acatatctgg
     8821 aacctcctct gctttatcag ataagataag gacttgctgg ttcggggcaa gattcttccc
     8881 ttcttcagca gaactgtttt taatcttcgt tcctgttccc acaacgatgg gttgtacaag
     8941 attgcgacgc aattcttctg ctaaatcacc aggtgaaata tccttgacac taggcatagg
     9001 ataaggactt tgttgactta cttgctctaa agccttagct gttgtttgaa gattgagaga
     9061 gtctttcata gctgaagccc gctccaagat aggattggca aattctccca actgaatacc
     9121 tgaataatgt tcaggttgtt ggaccgtcac atacaagata aaatcaggat tttcagccgg
     9181 actcatcgat acagccgaga aaatatagtc ggttaacccg actagataac caccattttt
     9241 ctcgtcagca atctgagccg taccagactt gagggctaca ttttgcccag gaacagttac
     9301 agttggcttg cctgtgctgt ggttatacat ggttccataa accggatccg tccctaccaa
     9361 aaccatgtta gtccgagtta gactagctgc atctttagaa acaggatttc ccacaatttc
     9421 tttttgagat ttccgagcag tttgatcatt tggatcataa atggcactaa taaatttagg
     9481 ctccagcatg acaccgtcat tagcaatagc tgtaaaggca cgaatcattt gcgtctgggt
     9541 cactgaaatc ccttgtccaa atgagctttg cgcaatgttg acaatattat ccgcaggaag
     9601 ctgaccagca tactcatccg tcaaaccgaa acgggtcgga actccaaatt taaaacgatt
     9661 aagataatca agccaggtag catctcccat cttttgctca aggagggtca tcccaacgtt
     9721 acttgagtgt gcaaaacctt gagaaaaagt catcgttctg ccaccagtca atccttcatt
     9781 aacgtcccaa tctcgaatcg tggcatctgc aatttttaac tcactactat taaagacttc
     9841 tcctcctgga aaggtattat tatcaatagc agcagccaac atcatcactt tcatagtgga
     9901 acctggctca tagttacttt ggtaaaggat atcacgccaa acaaagtcct ctgtaatgcc
     9961 ttcttttgta tctgcatcaa aggtcggtcg ttgcgttgtt gccagaattt cccctgtttt
    10021 agcactgacc aaagtcgctg tcatgtactt tccttttacc ttctcttgaa aagcatccat
    10081 ctgggtttcc ataaaggact ggagggggct ggaaatggtt gtataaacat ccttaccgtc
    10141 catcgttcgt tgggaaactt gttctgttcc gggtacaata ttacccagac gatccttttc
    10201 ataggtaata atgccgtctg tccctgcaag aatactgttc aaggaactct ccattccaga
    10261 ggttcccagc aagctcttgc ttccatcttc attttcatgg agctgagcta gaccgataaa
    10321 actagaagca aattgtccgt ttgggtaact acgattggga ctggttgtaa aatcaatccc
    10381 cttgacctct gcagcttcca attctttttt gatagacatc atattggcat aggtaatccc
    10441 atttcccttt gctccaaagg aaacttgctt gagattaggt tgcgagagtt gctctcttac
    10501 ataggattct tccatgtcca gatacttatg aaagacctct gcaaccttgt taaattgtgt
    10561 tttttctacg taaagaatct tacccgttgc tgacttatag ttctcatcaa tgaccgcata
    10621 gacattatag gaggttgcat cctcagcaat cgggactcca tttcggtcat aaatagtccc
    10681 acgtttggca ggaactgtac gggtggtttg atgaaccttc ttagcttcct tcgctaaatc
    10741 tgttccaaag cgagtgcctg tcccaataat gaccgcaaaa ttgactaaaa aaatggcaaa
    10801 aacaaagaca gataataaac tcagactttt tccaactctg cgtctgtttt cagccggcga
    10861 tttccgattt ttggtcgcat aacggattac tctttttgtc cacttcatat cttactccgc
    10921 tattctaata ttttcattgt ttaattgcaa atcgtgtgaa ttggcaattt ctttcaaacg
    10981 ttctgcacgt aatagttcat tgacctcttg cttggcatcg tccaattcgg tcttcttttc
    11041 ctctatctgc gcattgattt ttgtcaaatc attctgcact tgcaagagct tggtctgcat
    11101 aaaaataata ctaatggcta caataagagt ggttacagca atggaaaagt aaaaagcttt
    11161 ttccacacgc gaaaaccgtt taagttgcat ctgtagtatt tgacctgttt tttccatttt
    11221 ttctgccatc tttttccctc ttacttgtga atttttctga ccacgcgcaa cttggctgag
    11281 tgcgagcggt tattggcttc taactcttcc gcacttggca agattggctt acgggacacc
    11341 aattccatct tgggcttgag atcatctggg atgaaaggca agccttttgg aacttcaact
    11401 gttgaagctt ccttgaacaa ttgcttggtc aagcggtctt ctaaggaatg aaaggtaatc
    11461 actgaaattc taccatccag agccaacata tccatagcct gctggatgga ctcatctgcc
    11521 gctcccagtt catcattgac ttcaattcga atagcctgga aaatctgctt agcaggatgc
    11581 cccttcttct tgagttcctt ggcaggtttg accaacttga taatctctgc taactcagtc
    11641 gttgtctcaa tcggcttcac ttcacgcgct tgctcaatct tacgcgcaat ctgtttagag
    11701 aatttgtcct ctccatactt gaagaaaata cgaaccaagt catgatagtc ataattgttc
    11761 accacttcat aggctgtcag gctagcatcc tgattcatcc gcatgtccag tggcgcatcc
    11821 tttttataag aaaaaccacg ctcacgctgg tctaattgag gactagacac tcccaagtca
    11881 taacaaattc catcaatttc ctgaacacca gcttcgcgca aacatgcctg taaatgacgg
    11941 aagttgtcct tgataaaggt caccattccc ttctcaatgt aaggtgccaa gcgtttttgc
    12001 gcattgtcaa tggcattctg atcctggtca aaggcataga gatggccttt ttcacttaat
    12061 ttacttaata aatactcgct atgtcctgct ccgcccaaag tcgcatcaac gtagatacca
    12121 tcaggcttta cgtcaagcat atcaatcgtt tcgtggagta agaccgttac atgatgaaat
    12181 tcttttgtca tatcttatct attttaccac aaatccgacc agcttgcact tgtcagacaa
    12241 ataggacaag gagactacta tttcttcaaa aaatatgtca aaaatacttg acactttatg
    12301 tttaaaagac tataatatag tcaaatatat acgacataaa tcagaaagga gaacagatga
    12361 atcgtgtgaa agaatttcgc aaggaattgg gtatttccca gctcgaactc gccaaggata
    12421 tcggtgtctc gagacagact atcaatatga ttgaaaacga caagtacaat ccaaccttgg
    12481 aactctgtct caatctcgcc cgcagcctcc aaactgacct caacagtctc ttttgggagg
    12541 aagattttta aaaaaggagc aaactcatga aaaaagaaac cttcactgaa aaactgatca
    12601 aacgcacata cggtatttct ggtccccttg acgaatacaa acggcgtgag gccgatagta
    12661 ttgggaacca agtctttatc atcctctttt atctgatgat tttcggaaat cttattccac
    12721 tccttctggc ctataaatac cctcaagaag tggctctaat ctatcctcct ctgattttag
    12781 tgattgccct catcgcttct ggctatgtca cctaccaaat gaaaaaaaca ggcatcacag
    12841 tcattgaacc agatatgctg aatgagaaag aaagcaagca actacactac ccaggtctga
    12901 aagcaggttt gttctttggt ctatggatgt tttttataac tcctcttctc aggatactca
    12961 tagatgaagg tcaggactat tttcattctc ttctcactat aagaaatggt gtatcaagta
    13021 ttctcggttc tattttcttc ggagcgagca tacagttcct catctcccgt cgcattgcaa
    13081 aaactaagaa aaatcaagat gaggattagg aggaaactca tgaaaaaaga aaagaaacag
    13141 ttacgttatc ctggtctgaa agcaggttcg atttatggaa cagtgatatt ttttataatt
    13201 ccactcattg ataccctaac aagtgaaaat ccaaatttta tcagttctct tctaaataca
    13261 aaacatattt ttaaaactat actgggagct ttctttttcg gagtgatgat acatattgtc
    13321 gactcacttc gtattgcaag agctaaaaaa gaccaggatt aggaggtgcc ttatgaaatc
    13381 actagctaga ctactgatca ttcatgtttt tatcagtatt ttccttttct tcgcccttac
    13441 ttcaggagct atttctcata cagttttact actcctactc ctctttcttc ctgcgctcaa
    13501 taaaggactt gagaaaatac aatcaaaacg gatacctgtc ctcaacgcag ccctcttctt
    13561 tctcctcata tcctttccac aacttttaac caaccctgtc caatggaaat tttcaatatt
    13621 cctagtcgta accatcattt caagtttggc ctacttctat aacttttatc aagtagttaa
    13681 agaagtagat caaaaacagt tgatttagga gcttgctccc ataatttctc atttcatagg
    13741 caaataatcc cacctagctt gttctaggtg ggattatttt atttcttaac agagattgca
    13801 agtcattttc cttcatttta gaaagtcgac tctttccaat tcacactaca atccaagact
    13861 tgttgccttt cttcttgatt gcgaccttca atctggtcaa tcaaaatctt tgtagcctgt
    13921 tgtccttcct caaaggaggg ctgaaccagc gtcgaaacac ttggagaaga aaagcaagtc
    13981 cactccgtat tgtcaaaacc aatcaaccca acttgtggca agttataatt caactctttg
    14041 ataacggtaa agactagagg tagggcccaa cagttaggga taaataccag agttttttca
    14101 tcgggatcga tttctttttg taaaaattcc ttaatttgtt ccaaattcgt atgcttatct
    14161 tcaatggtta gactggcgtg acgcatatta gcatctgtta aagcatccac aaaaccactt
    14221 gcccgctcaa tccgagtact caaacgactc gtatccgctg taatcaagag aaaatgttca
    14281 taaccttttt cgatacagga ctgggtcatg tcataaacgg catcatagtt attggtttta
    14341 acccagctag tccggtgttc atagagctga ctatcaaaaa agaccatttt cttctttttc
    14401 tcatcgatga tacgagaata ttttcggaaa ttagaggtcg gctgaataat aaagccgtct
    14461 actcccaaga gaagcatgct ttcaatatac cggtcctcac tctcttggct gtaattacta
    14521 tttcctatca ttacctggta gccattctgg ctggcgatat cctcaattcc cttaacaatt
    14581 tggtttgaga aactgttggt aatatcacca atcaaaacac cgattaattt tgttcgtttg
    14641 gagtttaagc tacgcgcaac aatgctcggt ttgtaatttg tttcatgaat aactttttca
    14701 atcttttcac gtgtctcttg ggacattttt tcatatttcc cgtttaggta aaatgacacg
    14761 gttgttttcg aggtctgagc catttccgca atgtctttta tggtcagttt cttctccaat
    14821 ctaaaacacc tcctactaat acttattata acatattcac tattcaaaat gcctatttct
    14881 agcactgcaa gcgaatcatt ctctcattta ttttatcata tactaaacat tttccacgca
    14941 tttttgttcc gtcaacgagg cacaattttt cacctacacc aatatcctcg cttaataaca
    15001 gaatcagctt gtctgtttca tcatttttca cttcaaaagc cagagcattt tccacttcac
    15061 gatcatctgt ctggtagaca gaatgacgga tgatttcaaa actctcatgc gcaatgatgg
    15121 tataatccag catctgattc tcaaagaatt ggcgcttggt gagtttgcta cttctttcaa
    15181 gctcattgta tttaggagaa atgatggtat cttccaaatc aaaatcaact tcactccata
    15241 gtctcaactg attgattttc ccatcttgat aggtcacatc cttgtcaagg ataaactgag
    15301 tcaacacctc atgttgacct tgacacctga tgtcatctac caagagccag acatcctcta
    15361 ccaacatgag gatttttctc ctgtgaagat aaggcaaatc aggttctgct gaccaataag
    15421 ccccctcaat ataatgcact ccctcccttt ctttatggtg acaaaacagg gagtgaggat
    15481 agtattcata ttcccaggat cccgtgattc tttccggagc tttcccatct acaatgcagg
    15541 tcgaatgact ccaagcactc tttaagagat aacgttcata tatctcccga taagaataac
    15601 gcccagcatc tatgaaaata ggttggcctt gatactgtaa gcaaaaacta ttctcgtcac
    15661 tatgactatg ggcacttcct agcggaccat ttttgaaaaa tagataacga tgttcatcct
    15721 taatgcagac atgtccagag tcttcaaaga tcatggactt aggctgccaa gctctctttt
    15781 caaattcctg cagtcgcttg accttttctc gccccaggaa caagaggcta agcaaatcaa
    15841 ctttaacgtc cagaccgtta agaaggtctt cctggttcaa aaccacagca gacaggctca
    15901 aaatttctgt cgtttctgta gaatcgctat caccaaaagc caaagtccgt ccatctaagc
    15961 ctgtcatcat ttgaatatag gtcgccatct tttccagcaa ctcttggtaa ctatcttgca
    16021 agtctggaag caagagacac aaatccagca aggctttata aacctctaca tgatagagaa
    16081 tcgactgttc aaactggctt ccatctccta aaatctgtgt ctcaatttgc tgtttcaact
    16141 cctctgaagc aaaatggtaa gcttcttcta gatccatctt atctgaaaag aaatgataga
    16201 tagcaagcat cggaattgtt tgtaaaatcc cccagttact aagggtgtac ttggcgcgat
    16261 agtagctttt cataaagtca atctgctttt ctagactgac caaaattttc tctagttctt
    16321 tctcctctag caagtcaaat ttcaagagga gcaagagtag tttcaaccaa gtaaaggaac
    16381 gaatacccgt atccaaggtt ctagtcatca aggattgagg agaaaattct ctcacctgct
    16441 caatccaatc aaatagaaag aacttgcact tttgaatata gtccttatct ccttctacca
    16501 gataccctat cataaactgc aagagatatt cttgtcgatt gagcatataa gaccattctg
    16561 gatcatcttc aaatacttga tcccatacca tcggctggat ttgatggatt tttgaacaag
    16621 gctccatatc ccaaggacta tcaaacataa aacgattgtc catcaagcgt tcaagggaac
    16681 tcttgacttt ctcatagtct tttgaacagt gcgacaagat ataatcacga cattgatttc
    16741 catcgactct ttcaaaaaat tgtcttcttt cttctttcat tatctattac cagaaaaaga
    16801 actacttaaa aagcagttct tttgtctttc ccattacact ttccttttct acatggatga
    16861 ccacaccttt tgcaatctgc aaggagacca agtcatcttg gatagaaatg atttttccat
    16921 gaattccaga caataacaac acttcatcac caaatgttaa agaagctaaa tactcttgtc
    16981 gttgctccat ctgtttgcga agcaactttt gctgacgaat agaatgaaag cttgacagta
    17041 aaaggggact cactgccaag acaatcacta ttccataaaa caatgttgta tccattaagc
    17101 tataatctta agccagcttc cgataattcc gatgataact gttaaaataa cgagtttata
    17161 tgttgtccat ttcttttctt tgatcaagta gtaaactaaa agtgtaaata gggctggtag
    17221 aagagctgga gcaaccttat caagcattcc ctgaatactt acgatacttt gtttagcgtc
    17281 tgctttaact tcccctgcag caaaggtaat cggcaccata atcttaacag atgtcgctgc
    17341 caaaccagca attacggtta caccgataat attggcaata cgagaaatcg ttgccatctg
    17401 ttcgcttagt ttatcaatca cagttgttcc tagtttgtat ccatacagac cagttgacaa
    17461 tttaatcgct gttaaaatcg tattcatcgc aaggaagaac aagattggac cgacaaccaa
    17521 gccttcttga gcaaacgaag ctgcgatggt tgagaacaat ggagctaaac agaattgaga
    17581 aagagaatcc ccaatacctg ccaatggtcc catcaaggcc atcttgatgc tacgtgtttc
    17641 ttttgccgga cggccatttt ccaacattac aagatgcaag ctggtaataa aaggcaggaa
    17701 gtgtgggttg gtattataga attcacagtt ttcttccaag gcttggtaga aaccttcctg
    17761 atcctctcca tagtgttttt tcaaagcagg atacatcaca ttggcatatc ccaacccttg
    17821 atagttacta tagttaaatc cattttgaca aaagaatgcc cgcaaagacg ttttaagata
    17881 atcacgtttt gttaatttgt tagatccagt catcgtgtgc ttcctcctct accacatgat
    17941 ccgctgtttt tggcttgtta taaaattcaa tcaaagcaaa gatagtacct acaattgcaa
    18001 taccaattgt tgggatgttt agataagctg cacaaacata tcccaacaag acaaagggaa
    18061 tcaactcttt cttagccatc actgacaaga tcatcgcaaa accgatagct gggagcattt
    18121 taccagcaac tgtcaaacct gtaagtaata ccggtggaat gtagtctacg agtttcaaca
    18181 aggtatccat tgaaagggca cccaagcaac ccaaggtaaa tccaataaag gcaaacaacc
    18241 aaattgttgc atttagagtg aacttaaatt tcttcaaatt atggtttttc aagtgcttca
    18301 tagctgtttc aggcgcacca gcacgtacag tgtaggcgaa agtttgtaag aattgaatcg
    18361 ccacagcaat cggagtagag agggcaagag ccgcttctgg actgacttta ccagcactag
    18421 tgatagccat caaggtacca aagataccag gtccgattgg gtttggtgga acagtacctc
    18481 cagcaccaac accgaatccc atataagcca attcaccaat agctcccatt gcaagagcag
    18541 taggcagatc acctagaata attccgacac caaatgacag aacaatacat ctattggtgt
    18601 aaattcctaa cagcattcca ctaaaacaga aagctgtcca taatccaatt aaaatcgctt
    18661 gaaatacatt aatcgacata acgatctcct cttttaaata tagtccataa tgttgacttg
    18721 aacagctcca tcatttcctg ttggagttgt tttcgtatta aatgttactt gatgagtttg
    18781 gctcaattcc ttgagggccg ccttgtcctc ttcacccagg aagatggagc gtgtcacttg
    18841 ctctttacca ggggcattgt gaatgttccc aatattgatt tctttgatag tgacaccacc
    18901 ttctaccaag gttaaagcgt ccttcacatc ctttacaacg ataaagatcg tttgagcagg
    18961 attagccttg tgaatgatat caatcacctt ttgcaaaggg aagaaacgca tggcaactga
    19021 gtctggcaca actgttttca tcagagtttg ttgcatcttg tccgtgctta cttcgtcatt
    19081 ggcaacaatg accgtattac aacctaggta ttttacccaa agttgtcctt gtccatgaat
    19141 caaccgttca tcgatacggg tcataataat atttggcatt gtcatatttc tcctcctacc
    19201 aatataggtt ccagtctttg tagaaacgga taagggcttc taggtaatag tagtcacccc
    19261 agatattgcc ttcatccact cctttacctg aatgccatga gtacacaccg tggaggagac
    19321 ttgtcccacc aggggtaaat tgatcatttg cataatgttc gatcaaggaa cgaagcatgg
    19381 catgcatagc atgtttataa atatctttgt cagcatccac ctctgggaga tgttttagca
    19441 tttcatgaat cccacagacg gcgatagctg ttgctgaaga atctcgtgat tgatcactac
    19501 catcattaaa aatcaaatcc caataggaca catgatcttt tggcagacga ttcaagaaat
    19561 aattggtcac acccttaaac aagtcaaagc aggactcgtc ttttaagtga cgataagtca
    19621 aaggaatacc atagactccc catgattgac cacgtgccca gcatgaatca tcactatacc
    19681 cttgtctcgt tacaccttta aagggttgac ctgtctcagg atcaaaatag aaggtgtgga
    19741 aggacgaagc gtcatcacgg attacattat tagctgaagc atagaaatgg ctttctgcaa
    19801 tatcgtagta tttttgatcg cctgtttctt gataagcaaa gaataagagt tggatattga
    19861 gcaagcagtc gataatcaaa cggtaatgct ctttcttgcc caagtctccc caagcttgaa
    19921 taaaaccacc tttttcttga tagcgttcaa tcaacttatc tgcagctttc aaggttgctt
    19981 ctctagcctc tccatctcca tttatcttat attcagccat acaagacggt gtgtacaaga
    20041 agccgagatc atggtgatcc aattctactc tcttattgac acgatccagg aaagaaagaa
    20101 catttttatg agcgatgttt ttaaatgcat cctgttgact gtattcataa gccaaccaca
    20161 gttctcctgt ccagaaacca ttggtccatt ccgtgttatc catgattgga tagacattat
    20221 caaaggtagc tggcgtcggg aaatcttcct tgaaatagtc aaggttgagt tctaactgcc
    20281 gaataacctt atcgattgcc tggccgactt cttctttcgt cagaagtggt acttctaaga
    20341 agcgctcagg cgattttatt ttttcaatcg taaccttttt tatcattctt ttacccttta
    20401 aatacccgat tcgaaatctt cttcctcttc ctctgcatcc gttgaaaaca attctttacc
    20461 atttacgact ccgccctggg ccgccactac tgatttatta acaacctcat caaagctatg
    20521 agccattcta gcaaagactg cttccattaa catggctaag ttcaaacccg agagaacatt
    20581 cattgtcttg gctggatttt ctcccattat ggtagaagaa accttgaatg gcgatcctcc
    20641 caagagatca cttaggatta aaacttcttc ttcatttgaa attgcaagta agattttttg
    20701 cttgagttca tctgctgaca ttccttccac aaagtcaatc gcctccacat tttcttgatt
    20761 acctgcaatc aattgtaaag aactataaat ccctgtagca aaatgtccat gccctacaag
    20821 tacaattttc atcttttctc ctttcttttt aggtttaccg gtttacttta tattccccat
    20881 tgtaatcctt tatttttatc ttgtcaatag tttttttaaa aaaatattag cgctttcatt
    20941 atctttttaa ccagtttaat agacagaaat ttcaaaatct tccgtttttt taggaaaaca
    21001 aaccttttta taaataaaaa tatttattta ttgacaaaac cggtttacta gaatataatt
    21061 tggttataga gaagtcttaa caaatttgaa aggaagtatc aaatgacaaa tacatcattc
    21121 tcaattgagc agttttcttt aaaaggaaaa attgctctca tcaccggcgc ttcttatgga
    21181 attggatttg ctattgccaa atcctacgct gaagccggcg ctactattgt ctttaacgat
    21241 atcaatcaag atctggtcaa taaagggatt gaagcttatc gtgaagttgg catccaagcc
    21301 catggatatg tctgtgacgt gacagacgag gacggtatcc aagccatggt caagcaaatc
    21361 gaacaagagg ttggtgtcat tgacatcctc gttaataacg ctggtattat ccgccgagtt
    21421 ccaatgtgcg aaatgagcgc cgctgatttc cgtaaggtca tcgatattga cttaaacgca
    21481 ccatttatcg tttcaaaggc agttattcct tctatgataa agaaagggca tggaaagatt
    21541 atcaatattt gttcgatgat gagcgaactg ggacgtgaaa cagttagcgc ttatgctgct
    21601 gctaaagggg gcttgaaaat gttgacccgc aacattgcgt ctgaatacgg tggagccaat
    21661 atccaatgta acggaattgg accgggttat attgccactc ctcaaacagc acctcttcgt
    21721 gaattgcaag aagatggttc tcgccaccca tttgaccagt tcatcattgc aaaaacacct
    21781 gctgcacgtt ggggaaatac tgaagatttg atgggccctg ctgtctttct cgctagtgat
    21841 gccagcaatt ttgtcaatgg ccacatccta tatgtagatg gcggtatctt agcctacatc
    21901 ggaaaacaac ctgagtaaaa atagaaagaa gatcttatga aaatcgcatt aatcaatgaa
    21961 aatagtcaag ctagcaagaa tcacattatt tacgatagtc taaaagaagc gacagataaa
    22021 aaaggctacc aattatttaa ctatggtatg cgtggagaag aaggagaaag tcaattaact
    22081 tatgtgcaga acggactaat ggctgccatc cttttaaata caaaggcagt tgactttgtt
    22141 gttaccggct gtggtacggg tgtaggggct atgcttgctt taaacagctt ccctggtgtt
    22201 gtctgtggtc tagcagtgga cccaactgac gcttaccttt attctcaaat caatggtggt
    22261 aacgccttgt ctatccctta tgccaaagga tttggctggg gggcagaact gaccctcaaa
    22321 ttgatgtttg aacgcttatt tgctgaagaa atgggcggtg gctacccaag agaacgtgta
    22381 atccctgaac aacgcaacgc tcgtatctta aacgaggtga aacaaatcac ccacaatgat
    22441 ttgatgacca tccttaaaat aatcgaccaa gacttcctca aagacaccat ctctggcaaa
    22501 tacttccaag aatacttctt tgaaaactgc caagatgatg aagttgctgc ttatttgaaa
    22561 gaagtattag ccaagtaaag ctattctaaa ccagaaagga actaatggat gacgaaaata
    22621 ttactgtttg gcgaaccatt aattcgaatt tcaccattag atgccaccag tatcggcgat
    22681 catgttgcca gttcgactta ttttggcgga tcagaaatta acatcgcttg taatttgcaa
    22741 gccctgggta tctcaacgaa agtttttacc gcactccctg ccaacgagat tggagatcgt
    22801 tttctcacat tcttgaaaca gcaccaaatc gataccagtt caatctgtcg gcttggcgat
    22861 cgaatcggcc tctactattt ggagaacggc tttggttgtc gtcaaagtga agttttctac
    22921 gatcgtaagc atacgagtat cagccagatt cggccaaaca tgctagatat ggattctctc
    22981 tttcagggga ttagccattt tcattttagt ggaatcaccg tagctatcgg tcaagaggtc
    23041 cgtgcgatcc ttctcctact cttggaagaa gccaagcgcc gaggaattgt cgtttcaatg
    23101 gatctcaatc tgagaacaaa gatgatttca gtcctagaag ccaagtatga attttctaag
    23161 tttgcacgtt ttactgacta ttgcttcggt attgatcctc tcatgattga tgaccaaaat
    23221 ctagagatgt ttccaagaga cagtgctagc ctagaagagg tggaaaatcg catgcgactt
    23281 ttaaaagaag cctatggttt caaggccatt ttccataccc tccgctctag tgatgagcaa
    23341 gacaaaaatg tctatcaagc ctatgctcta gaagaactat ttgaagagtc tgtccaacta
    23401 aaaactgcag tctatcaacg aattggtagc ggggatgcct ttatatctgg tgccctttac
    23461 caactactcc atcattcctc cctaaaaact accattgact ttgcagttgc gagcgcaact
    23521 ctcaaatgca ctcttccagg agaccatctc tccacttcct caactagtat tgaaaattta
    23581 ctggcaaatg cacaagatat cattcgttag gagaattaca tgaccaaatc agatacgatt
    23641 attgaactaa aaaaacaaaa aattgtcgct gttattcgag gaaatacaaa ggaagaagga
    23701 ctacaagcct cgattgcttg tatcaagggc ggtatcaaag ctattgaaat cgcctatacc
    23761 aatcagtatg caggacaaat catcaaggaa cttgtagact tgtatcagga cgatcagagt
    23821 gtttgtatcg gtgcaggtac tgtgcttgat gccgtaactg ctagagatgc cattctagct
    23881 ggagcaaatt acgttgtttc tccatctttc catgctgaaa ctgcgaaaat gtgcaatctc
    23941 tacagcacac cgtacattcc aggctgtatt accctcacag agatcacgac tgcacttgaa
    24001 gccggtagtg aaatcatcaa actcttccca ggtagtactc tcagtccagc atatatctct
    24061 gcagtcaagg caccgatccc acaagtttcc gtaatggtaa ccggaggagt cggcctaaac
    24121 aacatccctc aatggttcgc tgctggtgca gatgccgttg gaattggtgg cgaactcaat
    24181 aaactcgctt cccaaggcaa ctttgaccgc atcagcgaga ttgcccaaca gtatattaca
    24241 ctcagataaa atcataacta cccgtctaac gggtggttta tctcagagct ataagcccaa
    24301 atcatcagcc agcgcctaaa gacgctggct ttcacgttgt tcaagcctta ttgctcttga
    24361 ctcgtcactt gcctctttaa gagactttgg tattacttac cactatccct aaagggatcc
    24421 tcatattctt ttacactcaa tttatctagt gctatagtag attgaaactg gaatagtaca
    24481 cctctgcttc taaaacattg ttaaaaatcg atttgactgt cctgatcgat tttgtcctgt
    24541 tcttatttca ttttactata tatcatactt tactcgttct caaattttca tactcatgaa
    24601 gaaatcatcc actcgataat ttctttaatc ttgactatat ttcttaattg tggcttcatt
    24661 aagccctact ggacttacat aataaccttc ctcccagaaa tgccgattcc caaacttgta
    24721 cttgagattg gcgtgtttgt caaacatcat gagtgcactt ttgcctttta aataccccat
    24781 aaaacttgaa acacttagcc tcgacggaat actgactaac atgtgtacat ggtctggcat
    24841 taagtgaccc tcgatcattt caacaccttt ataactacac aagcgatgaa atatttcgtc
    24901 taaactactt ctatattgat tatagatgac ttttcgtcta tacttagggg tgaacacaat
    24961 atgatagaac acctccactt tgtgtatgat aaactatgag tcttttgtgc catatttttt
    25021 ctcctttcgc tttacaattg gattgaacac ctttattgta tcgcgtttgg agtttttttg
    25081 gtataacctt cgacgcgcac ccgtatagcg ggtggttgtt ttgtctcgca cctcacggag
    25141 cgagacggac taatatagtg gagtgaaata ggatacgaac aaattgatta ggaaaatcaa
    25201 atgaatttat agaaatcttt tagcagttat aacgttctat tctagtttca aaacgctata
    25261 gtcacataat aatgaagtaa aaaaggataa gtatcaactt atcctttttt aaaagaaaaa
    25321 tccgaagata tttggccttc ttcggatttt ttctattttc cacagtttca tgtaattcat
    25381 ctagatgatg aacaaattag ttgttctttc ctctacggaa tagataaaat gccccaagta
    25441 gcaagaaccc tagacttgcc aagattgact gaccttctcc tgtctgaggg agattctttt
    25501 gatccgaatg gttcttttcc tcttcagatt tttccttttc ttttgaattc tgtacttgtg
    25561 gctgagctgc ttgctctagc tttttaaaga cttcctgatc tggagctgat tcctgggttt
    25621 caggattata gtaggcaatc ttatattcat ccccttcttt tcgaatggta tagactccac
    25681 gtttcaaaac ttggaattgg ttggaaatag tagagacaga atcatcatat ttcacaatgc
    25741 cccaaactcc ttgtttagca tcataaacag actgaagggt ttcgttattt tcgatgaggc
    25801 tactttctaa ctcttttatc atttgattga aggtggcacg atccacgtta ggaatgagca
    25861 tatagccata agaatctcta ttttgcttat gagcctgact aatcgtaaga aattcatttt
    25921 caacttcctt gtctgactgt ccttcattga tatccttcca ggctcccttt tgcaaagcct
    25981 tactcatact gattgaactc ttcttaaaga aaaagtaacc aatattcttt ttcgaatcga
    26041 acgattctaa aaagacactt tgggtttcag gataatcctt ttcttgttct gtaagggagg
    26101 cttctttatc attgacatag actttatatg gattacctga ttccagtttt ctctggtcaa
    26161 ttgtagttgc agcagtatct gttgaagtgt tttggatatt gcttcctaaa aaggcgatct
    26221 tatcctttag cataaaccag ctcttatgag cagtcaatgt ttgattccag ttggtgaaat
    26281 ccatggttgc tgtcgcattg gcatcatcta gtttgctcgt tccaacgaaa gcagacggta
    26341 aaactttacc tgtatcgcta tccgctctct tagcatccgt ctctgttgta ccaggcatct
    26401 tatatggatt aactgttggc cagtagccat cgctatagtg actcaaatcg ccattgtaaa
    26461 gatagaacat cccatcactc gtataccaac cacgtttatt ttccttgttc atgtgttcgt
    26521 aattcaaggt acgactggaa aagagtgaca agccaaatcc aaaccctttc tctgcattgt
    26581 acatggctgt tttatccatc ttgttaaagg cagataggta acttggtctt ggaacacttg
    26641 cgactcctgc atcacttaac aaggattgca tcaaactgat atccttataa gtcttcaaat
    26701 tcttaaagac atcataataa ctatccgatt gaacaatggt cttcacaaga ctctgcaaac
    26761 attgtttggt ttctccttca gacatatccg ctattcggtg aatccctctt agtacttcta
    26821 ctgcggccac gtgcccctcg ctatttgcac gactgatcga gcgtccacga ctcatatcca
    26881 tcaactctcc attcaccagc aaaggagcaa acgatttatc aatccagtgg tacatggttt
    26941 gcattttatc tttatcgatt ggattcttgg tcttttgaat gactggcaac agttgagaca
    27001 ggccatcaat caaaacattc ccataagcac ccgtataggc aacattggtg tggtcgatat
    27061 aggatccatc ttgataaaaa ccttcacctt ggtctaccaa cttgaacact tgctcaatcg
    27121 agcgaatggt agaagaaatt tcttgatcat ccttacgcag taaaccagct attactttta
    27181 cccttcccat atcaactaag tttccaccta gagccttgaa tgggttatca gtcgtctttc
    27241 ggaaatgttc gggatctggt acaaattttt caatcacatc tgtatatttt ttaatttcct
    27301 catcagagaa gtattctttc atcagagaca aggtattgtt gatggcacga ggtgtaccga
    27361 tttcataatc ccaccagttc ccaacaatgc tcttttcact attgtagaca tgtttatgca
    27421 tccattccat ggaatccctg actgttcgaa cgacagtttc atcttgataa taacgagaag
    27481 aaggattggt cacttgcttg gccatctcct ccaatttccg ataagtggca gtcagatttg
    27541 cagacgtttt ataatttgaa aatttttccc acaaataggt gcggtccgcc tgacttgaaa
    27601 tactggatag gctatcagct acctttcctt ccaattcctg gtttaatttg gccatctgtt
    27661 catttttaga atcatagtat tgattcccag cgatgatgcc attccagtca tccaaacggt
    27721 ctgtgtatgc atccttaaca gaggccagaa tcttcaaagg aatctttttc acttccttgc
    27781 catctttact gacaatgaca ttggttgtcc cttccttaag aggttctaaa attccatttt
    27841 tgactgaagc aacgtcagga ttttctacct tataagtata gtccgcaaga gaaaaaacat
    27901 gtttttttcc aattggtaaa tcaatctttt cctcaagctg tttatctgtt tgagaatcct
    27961 cagaaagctg gtctgctacc tctaccagct caatatcctt aaaggaaaca gtcccagttc
    28021 ctgtttcata gaataactcc agcttgattt tatcaacatc taaagtcggg ctatagtctg
    28081 cttcaatggt ctgccagtcc tttgttcctg acgtcgttgc agaattccac aatcgcttgt
    28141 ccttaccact ttcctcaatg atacgaactt tggcaatccc gattttatta tctgttttaa
    28201 tcttgaaacg cagtttatac tttttcttag cttcaatagg aaccatacgg tgaagcgctg
    28261 cccttaattt ctcatggctt gagatagtga tagccccatc cttagcctca atgactcgag
    28321 ttgaggcatc tgcactattc ttctggtcta cccaagctga ccacccctga gctttgcttc
    28381 ctgtccacgg actgcttccg tcctccgtct gaccaaaatc accattttca actaaatttt
    28441 ttgtatccct ttgctgatac tgaacttcct tctggctttg ctgaatggta ttcgtagtcg
    28501 tttcttccgc tccaattgtc atataatggt ttaataaaaa tcctgataaa acaagtgaag
    28561 acaaactcac aatgagcttc tttgtttttg tttgcatgta tacactccaa taaacatatt
    28621 gtaaaatcaa taggaactaa atctcaaatt agagatttat agcaactaag taaaccggtt
    28681 taattaaatc ataccatttt taaagttatt tgtaaacggt ttctatcata ttgaaggctt
    28741 attcttcaac aatatcttcc atccgactcg acgaaaaaag taaaaactgt tacaatgtag
    28801 aaaaagaaaa gaggccctca tgacttcact ttatgatttt tccgttttga accaaaacaa
    28861 ccaagcaact cccttggata gctatcgtgg caaagttctc ttgattgtca acactgctac
    28921 tggatgtggt ttaacgcccc agtaccaggg acttcaagaa ctctatgaac gctatcaaga
    28981 tcagggcttc gaaatattgg atttcccttg caatcagttt atgggacaag cacccggcag
    29041 cgcagaggaa atcaacgcct tctgtagcct acattttcaa accaccttcc cacgttttgc
    29101 caagattaag gtcaacggta aggaagcaga ccctctctat gtctggttac aagaccagaa
    29161 atccggccca ctaggaaaac gagtcgaatg gaatttcgct aagtttctca tcggtcgaga
    29221 tgggcaagtc tttgaacgct tttcttcaaa aacagaccca aaacaaattg aagaggcgat
    29281 acaaactcta ctataattca caatctcact atgattaggt ttcctttaac ctgatgaata
    29341 gtgagatttt ttgatgggct ttgacttaaa tagaaaaaca ccccatgata tgaaacatga
    29401 agtgttgtaa agtctatgtt gtaggtgctt atttcacaat ttcaatgtga ccagtgataa
    29461 cgaataccat acagaatctt catatacact aaacaaatga ctttctaatt atttcaatta
    29521 gttttggcta gtaaatatca tttccaacaa acgccctctc aattccttat cctgatgatg
    29581 caagatattc attaagtcat gagagttttt cgcattgatg aattgattta acaatctatc
    29641 ttttaattca tatggaagag aagctgtctt tagtagtcta aaaacttcgt catttaaaga
    29701 tgtcctttta ttatctttcc attcaaattt agctgtatca ttcttatttg gcaattcaat
    29761 tatagacaca ttcgttcctt taaaatgaat tctatgtttt ctattgcttg gaacgatact
    29821 agaatctcct tgtaatgcta actctaccat tcccatttcc caatcgattg ataatcttgt
    29881 tttatatctt tgaccatttt gatcttcaag catttcaaaa gaatgttgtt ttcctgggaa
    29941 tacataccaa tctacaactt caggtaaatc aacacccata cctatctcag aaccaaccaa
    30001 gggaatgatt gcaccacttt ttgcaaacac aggcgtagtc gagatgtccc tataaacact
    30061 taacttcaca ccacctgtgt attttttctc tgaaaagaag tcataccatt caccttcagg
    30121 gaaccataca tctacttttg cagattggaa tgtcaaatcc atcttttcta caatgggagc
    30181 caccatcagt tctgttccaa aaaagtattg gtttggaaca ttatagctct catcattctc
    30241 tggatagaaa taatagattg gactgattaa tggggcacct tcctcatgtg tctgtacatt
    30301 catggtatat agatagggaa tcatctgatg tctcaaacga aggtatttct tcataatctt
    30361 agatgttgtt tctgaaaaaa accaaggttc tttactatta aaaggacttc tagaactatg
    30421 taatcgagta atcggactaa aaacaccaaa ctgtagccat ctagtttgta gctcttcgtc
    30481 ataatccccc aacatatgtc caccgatatc atgactccac caactataac cgatattaga
    30541 tgctgtcgct gtaaaatagg gttgaaatct taaggaattc caactaataa tagtatcccc
    30601 tgaaaaacca acagggtagc ggtgactacc aggacctgca tatcttgata aaatcaaacc
    30661 accttctgca tttttacaac tatcctgata gtgataatgg tttaaaagcc aaagtggatc
    30721 tagcatacct tgtgtccctt gttgccagtc aatccaccaa aaatctactc cctgcttttc
    30781 tagttcataa tgaacatctt taaagtaggc ttccctaaaa gagggattaa aaaaatcaaa
    30841 aatagcaggt tcttctagtt ctacatttaa ccccaaccgt tttgcgattt gaggataagc
    30901 ttcttcataa gcccgtatcc catcagcagg atggacattt aaggagagtt ttagctttct
    30961 atcatgaagt tgttgcaata actgttctgg atttggtatt aagtttctat tccaactata
    31021 tcctgtccag ccacttccaa agcgagctgg aatgtcagtt atatgccaat ccatatctaa
    31081 cacaccgata gataatggaa ttttctctgt ttcaaatctg tctattaaat ccaagtattc
    31141 atccgacgta taaggccaat atctactcca ccaattgcct aaagcatatc ttggcaacaa
    31201 gggtgttgaa ccagtcaaat ggtaaaaatc tctgattgct cctctataat catgcccata
    31261 ggcaaagaaa tacaggtcaa tttgattttc tctctcaata taaccagatt gttcatccca
    31321 aataaatcct tgagaatcat ccaataaggc tataccattt cggctaataa ttccatcttc
    31381 taacgagatt gctccatctg ccttatccag agtccgagct gttcctttta acgtttcaat
    31441 agattcacca aaataccagc gactaccata tacggcaaaa tttcctttta attctataaa
    31501 taaattttcg gcgttaaatt ctcctttatt aaagtgcaga tgaaaatagt ccgtcataat
    31561 atctagtacg tttgatgtct cgatataatc taacgaaatt tggccaaaat ctctattata
    31621 gataagttgt gtcgttctat cctcaaaact tccagtttga gagtattcta accttactag
    31681 cttgtctgtt aatacagaga ttcgataaaa ctctccctta aaaattttca atttgttttc
    31741 ctccttttat ggtagcataa aaacagaacg caccattttt gatgcgtttt tcattattct
    31801 gaatgcaatg ttctatctgt tatatctatg acaaataata gtcaattgaa aaaatgcagt
    31861 ggacaaaata tcttttaaca aaccaagagt ttattaaaga gttatcactt ttcaactttt
    31921 ctaagcttat gcagttgtga aacaaactac ttttaaacta ttaactaaga taggattgat
    31981 aaataatttc aaactcttac tagcaatcat acgatattca agctcacgtg cttttttcct
    32041 tcctgcttat ttcttagaac tgaagaaccc ggatcggtat ataaattatc cggatcaaca
    32101 tagtcataag attcataaca gttgcgcttc attaagtcat ccccagagca agagcttcat
    32161 ctcgtaattt ttcaacatca ctaaccgtag gtcgccatcc ttcaatcata tttgtactta
    32221 aagcatacca aacactctta aaaacggatc ggttttcaaa agctattccc atgattgtca
    32281 tcttttcttt atctatatct aagaacatat gctacctcct ttagatacat tataccatgt
    32341 ttctctgtag cttttaaaaa ttttattttg tttgtcatat ctaagttttc agcacgctta
    32401 tcctatttta taagcctcaa acccaaatat aaaacgcatt ctttttgctt ttttactatt
    32461 gtatcgtatt ctacgataac atactttact ttattgtttt tttaaataac agcagttccc
    32521 tgtttatcaa ctattcgaac tactttctat tttgcttcat accctacata gcgaaaaaat
    32581 atgaaaaagc agagaagaat atcttaaaaa gacctcttca ctgctaatat taacactcat
    32641 tatttaaact atatggattc tatcatcgag tatacttttt tacttattag ataccttgct
    32701 cttctttcac caatttttga tcatatacac ggatgaatgg aagatagact aggaatgctg
    32761 caaatgcaca tactagagca actaatacag ctcgaagatc tgctgtccct aagaaagctc
    32821 caatccctac tggagttggc catggaacct gtgcgataat tggcttaata aagtttagag
    32881 aattcgctac gtaataaata gtagcagtaa ccattggtgc taaaataaat ggtatagcca
    32941 aggctggatt atagataata ggtaatccaa aaattaatgg ttcattaata ttaaataagg
    33001 ctggaactac agatgctcgt cctattgctt taagctgttc agatttagag gcaaaagcaa
    33061 tatataaaca tagtcctaaa gttgcaccag aaccacctgc aattacaaac atattagaaa
    33121 attcacctgc aacagcgaag tgcccgccag cagcattttc agccatgtta gcaagagcaa
    33181 ttggactaac aaatgcaaaa acaatgttcg caccgtggat acctacaatc caaagtagtt
    33241 gagtcaatag ataaataatc attaaaccaa tccacgaatt agtcagattg gatacaaaac
    33301 caaatggaat tgcaatgact ttaaaaatat ctgttcccat tgctacaaga agaccgttga
    33361 taaagataac aacaaatgca acaacaaatc ccggaaccaa agcggtaaat ccacgagaaa
    33421 ctccttctgg aacagcttca ggcattttaa taacccaatt atgtttaaca cacatacgat
    33481 aaataagaac agtcacaatt gccataatga ttgcggtaaa aatccctgtt gtcccaaaac
    33541 gtgcgactac atttcccatt gcccatccat ctgcaattac tgcaccttct tttagacttg
    33601 tcacagtctt catcattcca ccatcaaaaa tgatttgcgg tactgtcatg acaaaagcca
    33661 tcaaggcaag caaggcacca ttaagaggat tcatattgag ttcttcttcc tctgcataaa
    33721 tttttgtcaa ttcatatgca agtgatagaa cgaaataaag agatagagaa cccatagtcg
    33781 catagtttgc aaccatgtaa agtgatgtga atttatcaaa tgaagcagag aaaatatctg
    33841 ccacaattgg ccaaaatgag aaagcttgtg gcaaaatact gaataccaaa aacattgatc
    33901 ctacaatagt aaatggtaca gcagccatac ctgcagccgt gatagcacgt actactttaa
    33961 actgagcaag tttgcccatt ggtcccataa catggttttc aagaaaacca aacaacccgt
    34021 tttgttgatc cataaataga cctccttaat aaaacataat aatttttact ttctaaagac
    34081 tagtttcaaa tacaaattat actagatcag gattataaac taagtgagtt cttttccaat
    34141 tggacaaatt gttgataagc cttatctgtt cgtttataaa tttttttaat tcttctaatg
    34201 tctaacaaac tcagaactaa acctaataga agaactacaa aaacaaataa acgtgctact
    34261 tggttatttt caaaaatcgg aaaaagattc ttaaaccaac ttgtccaagt taaaacaagt
    34321 aatcctattg aaataagcat ttgtattcta acaaacatta gtgttattcc caacttttct
    34381 ttcctatttc cataaagttt aaattgttca acagttgcta aaatagaaaa tactatgagc
    34441 ataatgggga aaataataat aggcgaggga ctaataaact gactcaaaag ccaataaata
    34501 ttcccaaaaa agaagagtgc tattgaataa cgtagaagaa gatatcgatt gaaaaaagta
    34561 ttagttagag ccatctctcg acgttgttgt tcaatctttt gtcgttcttt tttatccata
    34621 tcatttcctc cttatataac aacacatatt tagttaactt tcttataaag agctaacatt
    34681 tcctttgcta cttctaataa tgtcatagtg gtcattaaat gatcttgagc atgtaccatg
    34741 ataatttcaa ttttaatttc cactccactt gcgtattctt gcaagagttt ggtttgtgca
    34801 tgatgcgctt caagaattat ctcatttgat tgatttaatt tactttctgc atcatcaaaa
    34861 ctaccttctc tcatttttgc aaatgcttca tgtatttctg accttgcatt tcccgaatgc
    34921 aggataattt caaatgctgc aacctgcagt tcctcttgat tcatataaac ctcctatttt
    34981 atcttctcaa atatgttaat aaaatcttca aagttattgc aagatattag ctgattttgc
    35041 aattcatcat tctctgtcag agagactatc tttttagtca cagttgccaa accttcgttc
    35101 ccatatattg atggagatag aagaaatact agctggacat gtgaactttg attatcccag
    35161 agtaacgaat ctttacaaat tgcaaccgaa acctttccct ctgtaccaaa gggctgaata
    35221 ggatgcggaa ctgcaatttt ttcagaaaaa acaactgaac ttaattcttc gcgctgttta
    35281 attccataaa gtaaagattg ttcaaactca tttgattcac caacagataa actctcaacc
    35341 atcttttcaa gtaaatttac cttgtctgat tcagtacata ttaaaaagtt ttctttacta
    35401 aaatactgtc taaagccgtt gttttcaaat ttgttaatct ttgatgattg tacataacta
    35461 gaaacttgca tctaatccat agcttttcta atcatttcca tctcatcact cttaagaaac
    35521 acactaactt taaaaactgg gatttgaaaa tatagatttg ataaatcaat agctgacact
    35581 ataaaatcta ttcctttaag tttttcttga ttcaattcat agtagcctat tacatcaaca
    35641 acttctactc gcttcccaaa ctccgtttcc aaacgatttc ttaacatttg ggctgcacca
    35701 aatcctgttg cacaaatagc aagaatatta aacttagtac tctctttgct acgttccata
    35761 gcagctaaaa agtgaagact tacatatgct acttcatcat ctgatattgt ccactccaag
    35821 aacttgtcca tatttgcaag aatttctcta gtcataaaga atatatcact ataattctgt
    35881 ttaatttcat ctaccaaagg gttatttaag gtaatccggc tttctaaacg tacttgtagt
    35941 gtcattagat gagttatcaa tccttcaatt agttggaaat ctgaagaaaa gttatacata
    36001 tcatctaatc ctaaattctg aaatgtttta aataaagatt tttttaaaac ttcttcagaa
    36061 atattcttct gatttttttg acattgttga ctcttagcta acaaatgcaa agtaatgtag
    36121 tctatttcct gaactggaaa ttcctgattt gttacttctc ttactttaga aagaattctt
    36181 tgggcaacct ttctctctat tgcatcatca gtcatctgac agtctatatt ttttatttca
    36241 aatccggatt ttaaacgaat cacagacaat gctatgtgaa ctactaaatt ctgtagtaca
    36301 aaatcagata gttttaggtt ggcctcttgg cattcatcca aaacaattct agcaaattct
    36361 tctaatggaa cagtttgatc aaaaaagtta aattttacat agcaatgtat tgttttaaaa
    36421 aattgattct ctaggaaata atttatgata aaacgtcgtt tatcacgttc ctcgcctgag
    36481 acataaactc ctttattcgc cctactctca atggacaaat tatactctga taacatcact
    36541 cgtatctttc tgaaatcatg agataatgtt gaacgactaa cgtaaagttc atcagctaaa
    36601 tcatcaaaaa gaactggaac ttgctcaaat aataatttat ttaagataaa tactaaacga
    36661 tcatcacctt ttgaaaccgc agttttcgta tagtcttctt ccagttcata agtttgtcta
    36721 aactcctggt aagcgccttg attctcaaaa aatatttgat acccttgacc ttgttttgaa
    36781 atcaaccgga ctccttgaat aatcattgtc ttctcaatta atttcagtac attacggaca
    36841 gttctatctg aacaggataa atattctgcc agttctttgc ttgtaacaaa acgttcctta
    36901 ttttttatta aaaattgaag gatatctttc tctttaatgt ttaacacatt cattccctcc
    36961 taaaacgtat gttttcatat attgaagcat attatacact taaatcagtt tatatcaaac
    37021 tcaaaacaat ttatcttaac ctaaatattt attgacattt catgtgttca tcaaatattc
    37081 tcaagaatca aattagccat tttttcaatt cccattggaa taggaatata ggcttgagga
    37141 ggtatttgta caactggttt tcctgcttta gaaccagcct cttcaaattg cttaaagtac
    37201 atttttgttt gaggactgac aagatacaaa tcaaaagctg ctgctgcgat agctttccct
    37261 ccttcagtag cactaatagc atcaactaca atatctttcc cttttccttt tagaaactct
    37321 gttgttttct gtgccataag tgatgaagac attcctgctg cacaaataat taaagctttt
    37381 gccataatat tttctccttt tcttaaatcc aatcaaagct gtgctaagtt ggcttatttg
    37441 ttatctattt ttattataaa ataaagcgtt tccaatgaca attccctcat tttcctaaat
    37501 gatatggaaa aaaattattt atacttcaat ttataaaata aaattattcc tgagagtaga
    37561 aatgaaacac tatttgctaa aatcaaaggc aagtctccta tacgaatacc atgagcaagc
    37621 cacaatgcaa taccaataac ttgcataaca tacataccta gagcaataga tcctgtgtcc
    37681 tttgtcttaa ctacacgaaa aacttgtggt aaaaatgcaa atgttgttaa aattgctgca
    37741 atacttccaa tcatatgtca cctcaatatg ctaaacaaac tgagaataat ctcagtttgt
    37801 ttatactatt ctactgattc accgttagat gaaataactt ccttatacca gccaaaagat
    37861 tttttcgggg aacgattata acttcccttc ccattatcat ctttatctac ataaataaag
    37921 ccataacgtt tccgcatttc accggtacca gctgaaacca aatcaataca tccccatgga
    37981 gtataaccca ttaaatcaac accatcttca actacagcct ttttcatttc acgaatatgg
    38041 gcacctagat attcaattct ataatcatca tgtaccatac catctgctgc aacttgatct
    38101 atagctccaa aaccattttc aacaataaag agtggtaagt gatagtggtc tgtaaaccaa
    38161 tttaacgcat aacgcaaacc ttctggatca atttgccact cccattcaga agccttaaca
    38221 taattatttt tcactaaatc ttctgtttca agataatcaa aataaggatt attttcacga
    38281 tgagagtcga tagcaaagga catatagtaa ctgaaaccaa tgtaatctac agtcccacca
    38341 agtaaatctt ctttatcctg ggcagtaaaa tcaactgaaa taccttttcg ttcccaatac
    38401 ttgaaaatat gctcaggata tttacctaaa acatgcacat cagcaaaata ataacgcttc
    38461 tgcatagctt tcattgccat taagatatcc ttaggattgc aagtaactgg ataaattgga
    38521 cacatcgcaa tcatacaacc tatttgaaaa tctggattaa tctcatgacc aatttttaca
    38581 gctcgtgcag aagcaactaa ttcgtaatgt gctgcttgat acataattgc ttctctatta
    38641 tcaccttcct catatacaat acctgagtta gtaaatggtg caaaatcttc ctgataattc
    38701 gcttgattat tgatttcatt gaaagtcatc caatatttaa ccttatcttt gtaacgttta
    38761 aatacgactt ctgcaaaacg agcaaagaaa tcaatcaatt tcctattttt ccaaccacca
    38821 tattcggtca ctaagtgata aggcatttca aaatgagata gagtgatgac aggttcaata
    38881 ccattcttta agcattcatc aaaaagatta tcataaaact gtaatccttc ttcattcggc
    38941 tctaactcat caccttttgg aaagatacgt gtccatgcaa tagaggtacg gaagcacttg
    39001 aatcccattt cagcaaaaag tgctatatct tctttataac ggtgataaaa atctatcgcc
    39061 tcatgatttg gataatattt accctctaaa actcccaaag taatttcacg agctactcca
    39121 tgacgaccag cagtcataac atcagcaaca ctaattccct tgccaccttc ttgccatcca
    39181 ccttcaagtt gatgagcagc aacagcacca ccccataaaa atccatcttt aaaagtagtc
    39241 atcttttttc ctcctgactt tgatactctt attataaacc ttaaaccaaa agatgaaaac
    39301 gcattctttt tccttattgt taaggaaaga agtaattttt aatggaaata gaacaatatc
    39361 ttcttgtatt ctcgtaatga tatctttacg attttcaata ctttcaaact acaaaaactc
    39421 tcacaataat tctaattccc tgtgtctata aacgacttat cgctttctgg catcccagaa
    39481 tcatcttcta tataacgttc aacttgcatc tgcaagtgat atttttttct taaatctaag
    39541 attttctgca ttgtctttga ttgataatgt ttatctaaag tttcttgatt tatccactga
    39601 tcaataagga gaatagttcc ctctttttca attggtaaaa aatattcgta tttcaagtta
    39661 cctttttgat ttctaatttc tttaacaagg ccactatcaa gcatttctct tgcaaacttt
    39721 attgcactat ctccatcacc tttataatat acatgaatag tcaatgtcat cttatatcct
    39781 ccaaaatcat ccttcaattt taaaaaaaca agtttagatg aggatctaaa cttgtttttt
    39841 atgaactaat tatctaacgt ttcgccatta ctttcaatca cttctttata ccaataaaat
    39901 gattttttct tatagcgatt tatagtcaat tgaaacaaga gcaggacaaa a
//
LOCUS       DAVFER010000019        38756 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1105170250
            SAMEA2167659-rid19724873.denovo.019, whole genome shotgun sequence.
ACCESSION   DAVFER010000019 DAVFER010000000
VERSION     DAVFER010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2167659
            Sequence Read Archive: ERR388902
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 38756)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38756)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928716.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928716.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 04:07:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,118
            CDSs (total)                      :: 2,073
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 120
            CDSs (without protein)            :: 120
            Pseudo Genes (ambiguous residues) :: 0 of 120
            Pseudo Genes (frameshifted)       :: 67 of 120
            Pseudo Genes (incomplete)         :: 47 of 120
            Pseudo Genes (internal stop)      :: 34 of 120
            Pseudo Genes (multiple problems)  :: 23 of 120
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38756
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2167659-rid19724873.denovo.019"
                     /strain="1105170250"
                     /db_xref="taxon:1313"
     gene            complement(31..1404)
                     /gene="mnmE"
                     /locus_tag="VU534_001004"
     CDS             complement(31..1404)
                     /gene="mnmE"
                     /locus_tag="VU534_001004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002906470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HEU1513609.1"
                     /translation="MITREFDTIAAISTPLGEGAIGIVRLSGTDSFAIAQKIFKGKDL
                     NKVASHTLNYGHIIDPLTGKVMDEVMVGAMKSPKTFTREDIIEINTHGGIAVTNEILQ
                     LAIREGARLAEPGEFTKRAFLNGRVDLTQAEAVMDIIRAKTDKAMNIAVKQLDGSLSD
                     LINNTRQEILNTLAQVEVNIDYPEYDDVEEATTAVVREKTMEFEQLLTKLLRTARRGK
                     ILREGISTAIIGRPNVGKSSLLNNLLREDKAIVTDIAGTTRDVIEEYVNINGVPLKLI
                     DTAGIRETDDIVEQIGVERSKKALKEADLVLLVLNASEPLTAQDRQLLEISQETNRII
                     LLNKTDLPETIETSELPEDVIRISVLKNQNIDKIEERINNLFFENAGLVEQDATYLSN
                     ARHISLIEKAVESLQAVNQGLELGMPVDLLQVDLTRTWEILGEITGDAAPDELITQLF
                     SQFCLGK"
     gene            complement(1541..1723)
                     /locus_tag="VU534_001005"
     CDS             complement(1541..1723)
                     /locus_tag="VU534_001005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005589823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-oxalocrotonate tautomerase"
                     /protein_id="HEU1513610.1"
                     /translation="MPFVRIDLFEGRTLEQKKALAKEVTEAVVRNTGAPQSAVHVIIN
                     DMPEGTYFPQGEMRTK"
     gene            1847..2446
                     /locus_tag="VU534_001006"
     CDS             1847..2446
                     /locus_tag="VU534_001006"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HEU1513611.1"
                     /translation="MAQLYYRYGTMNSGKTIEILKVAYNYEEQGKGVVIMTSALDTRD
                     GVGYVSSRIGMKRPALAIEETTDIFGYIRDLPEKPYCVLVDEAQFLKRHHVYDLARVV
                     DELDIPVMAFGLKNDFRNELFEGSKYLLLLADKIDEIKTICQYCKKKATMVLRTQDGL
                     PVYDGEQIQIGGNETYISVCRKHYFAPMITSNKEQNYDN"
     gene            2436..2915
                     /locus_tag="VU534_001007"
     CDS             2436..2915
                     /locus_tag="VU534_001007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU1513612.1"
                     /translation="MTIELRDVTMENYFDVLNLDVKEYQKQFIATNAISLAEAYVYTK
                     NGDFVAPLAVYDNDAIIGFVMIAYDKKIGISSGNYLLFRFMIDKNFQNQGYFKPIMDK
                     VLDYVRTAPAGLSNKLWLSYEPENEQARFCYLSYGFKETGEISENEVVAIYDLTIEK"
     gene            2925..4004
                     /gene="prfA"
                     /locus_tag="VU534_001008"
     CDS             2925..4004
                     /gene="prfA"
                     /locus_tag="VU534_001008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HEU1513613.1"
                     /translation="MNIYDQLQVVEDRYEELGELLSDPDVVSDTKRFMELSKEEASNR
                     DTVIAYREYKQVLQNIVDAEEMIKESGGDADLEELAKQELKDAKAEKEEYEEKLKILL
                     LPKDPNDDKNIILEIRGAAGGDEAALFAGDLLTMYQKYAEAQGWRFEVMEASMNGVGG
                     FKEVVAMVSGQSVYSKLKYESGAHRVQRVPVTESQGRVHTSTATVLVMPEVEEVEYDI
                     DPKDLRVDIYHASGAGGQNVNKVATAVRIVHLPTNIKVEMQEERTQQKNREKAMKIIR
                     ARVADHFAQIAQDEQDAERKSTIGTGDRSERIRTYNFPQNRVTDHRIGLTLQKLDTIL
                     SGKLDEVVDALVLYDQTQKLEELNK"
     gene            4004..4843
                     /gene="prmC"
                     /locus_tag="VU534_001009"
     CDS             4004..4843
                     /gene="prmC"
                     /locus_tag="VU534_001009"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000761890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HEU1513614.1"
                     /translation="MKLAQLFSNFEEELIRQGEEAESLSFVYRSLKNLSFTDFIFALQ
                     QEVTTEEEKQFVEDIYQQLAAHKPAQYIIGQADFYGMHLKVDERVLIPRPETEELVEL
                     ILAENPVKNLMVLDIGTGSGAIALALAKNRPDWSVTAADISQDALDVASENAKNQNLQ
                     IFLKKSDCFTEISEKYDIIVSNPPYISREDESEVGLNVLYSEPHLALFADEDGLAIYR
                     RIAEDAKDYLKDGGKIYLEIGYKQGQSVPELFRKHLPEKRVRTLKDQFGQDRMVVVDD
                     GQD"
     gene            4827..5429
                     /locus_tag="VU534_001010"
     CDS             4827..5429
                     /locus_tag="VU534_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000969311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonylcarbamoyl-AMP synthase"
                     /protein_id="HEU1513615.1"
                     /translation="MMDRIRQELENGGAVVLPTETVYGLFAKALDEKAVDHVYQLKRR
                     RRDKALNLNVASLEDILYFSKNQPTYLQKLVEIFLPGPLTIILEANDRVPYWVNSGLA
                     TVGFRMPSHPITLDLIRETGPLIGPSANISGQASGVTFNQILEDFDQEVLGLEDDAFL
                     TGQDSTILNLSGDKVKILRQGAIKREDILARLPKISFEEE"
     gene            5431..5862
                     /locus_tag="VU534_001011"
     CDS             5431..5862
                     /locus_tag="VU534_001011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014947335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU1513616.1"
                     /translation="MLRDLRETDVKAICDINQEALGYTFSPEETASQLARLSQDSHHF
                     LLGYEDAANHVLLGYVHAEVYESLYSKAGFNILALAVSPQAQGQGIGKSLLQGLEEEA
                     KRCGYGFIRLNSANHRLGAHAFYEKVGYTCDKMQKRFIRIC"
     gene            5924..7180
                     /locus_tag="VU534_001012"
     CDS             5924..7180
                     /locus_tag="VU534_001012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HEU1513617.1"
                     /translation="MIFDKDDFKAYDADLWNAIAKEEERQQNNIELIASENVVSKAVM
                     AAQGSILTNKYAEGYPGRRYYGGTDVVDVVETLAIERAKEIFGAKFANVQPHSGSQAN
                     CAAYMSLIEPGDTVMGMDLASGGHLTHGAPVSFSGQTYNFVSYSVDPKTELLDFDAIL
                     KQAQEVKPKLIVAGASAYSQIIDFSKFREIADAVGAKLMVDMAHIAGLVAAGLHPSPV
                     PYAHITTTTTHKTLRGPRGGLILTNDEELAKKINSAIFPGIQGGPLEHVVAAKAVSFK
                     EVLDPAFKEYAANVIKNSKAMADVFLQDPDFRIISGGTENHLFLVDVTKVVENGKVAQ
                     NLLDEVNITLNKNSIPYESLSPFKTSGIRIGAAAITARGFGEEESRKVAELIIKTLKN
                     SENEAVLEEVRSAVKELTDAFPLYED"
     gene            7188..8162
                     /locus_tag="VU534_001013"
     CDS             7188..8162
                     /locus_tag="VU534_001013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HEU1513618.1"
                     /translation="MDIYIKKAIIHQFSPDDTELFLADKFLNITPKIEEYLRKKIEHV
                     YSDEAKTGIFEEENPFFNHITDDLLETSVTLANLWKEEFSISENLKTNDLIFVQFSKE
                     GVEHFAFLRIALRETLTHLGGEVDNPIKLTQNNLPGFGTGADEALVVNLQSSKYHLIE
                     KRIKYNGTFLNYFSDNLLAVAPKISPKKSIKELEKTAQRIAKSFNTDDFQFQSKVKSA
                     IFNNLEESNELSPEKLANDLFDNNLTARLSFIDQVKEAVPEPVQFDEIDASRQLKKFE
                     NQKLSLSNGIELIVPNNVYQDAESVEFIQNENGTYSILIKNIEDIQSK"
     gene            8162..8776
                     /gene="pmp23"
                     /locus_tag="VU534_001014"
     CDS             8162..8776
                     /gene="pmp23"
                     /locus_tag="VU534_001014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000476388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall hydrolase Pmp23"
                     /protein_id="HEU1513619.1"
                     /translation="MFKRIRRVLVLAVFLFAGYKAYRVHQDVKQVMTYQPMVREILSE
                     QDTPANEELVLAMIYTETKGKEGDVMQSSESASGSTNTINDNASSIRQGIQTLTGNLY
                     LAQKKGVDIWTAVQAYNFGPAYIDFIAQNGKENTLALAKQYSRETVAPLLGNRTGKTY
                     SYIHPISIFHGAELYVNGGNYYYSRQVRLNLYIIKCFTLFSTSG"
     gene            8850..9824
                     /locus_tag="VU534_001015"
     CDS             8850..9824
                     /locus_tag="VU534_001015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1002 domain-containing protein"
                     /protein_id="HEU1513620.1"
                     /translation="MRKKLFLTSAAILWAVTAMNSVHAATDVQKVIDETYVQPEYVLG
                     SSLSEDQKNQTLKKLGYNASTDTKELKTMTPDVYSKIMNVANDSSLQLYSSAKIQKLG
                     DKSPLEVKIETPENITKVTQDMYRNAAVTLGMEHAKITVAAPIPVTGESALAGIYYSL
                     EANGAKVPQANKDLAQEELKALSDINAENKDKSGYDANKLNVALADIKSGLAKAKESK
                     GNLTEEDIRKIVEDTLKNYKLDQVITGNQINIIINFALNLSKSDILSNADFTKTLNDL
                     KQSIVSQAGDSFKNINLNFDADKALEDGGNFLSSLWQALVNFFKSFGS"
     gene            9898..11529
                     /gene="rlmD"
                     /locus_tag="VU534_001016"
     CDS             9898..11529
                     /gene="rlmD"
                     /locus_tag="VU534_001016"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000914584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HEU1513621.1"
                     /translation="MLKKNDIVEVEIVDLTHEGAGVAKVDGLVFFVENALPSEKILMR
                     VLKVNKKIGFGKVEKYLVQSPHRNQDLDLAYLRSGIADLGHLSYPEQLKFKTKQVKDS
                     LYKIAGIADVEVAETLGMEHPVKYRNKAQVPVRRVNGVLETGFFRKNSHNLMPLEDFF
                     IQDPVIDQVVVALRDLLRRFDLKPYDEKEQSGLIRNLVVRRGHYSGQIMVVLVTTRPK
                     VFRVDQLIEQVIKQFPEIVSVMQNINDQNTNAIFGKEWRTLYGQDYITDQMLGNDFQI
                     AGPAFYQVNTEMAEKLYQTAIDFAELKKDDVIIDAYSGIGTIGLSVAKHVKEVYGVEL
                     IPEAVENSQKNASLNKITNAHYVCDTAENAMKKWLKEGIQPTVILVDPPRKGLTESFI
                     KASAQTGADRIAYISCNVATMARDIKLYQELGYELKKVQPVDLFPQTHHVETVALLSK
                     LDVDKHISVEIELDEMDLTSAESKATYAQIKEYVWNKFELKVSTLYIAQIKKKCGIEL
                     REHYNKSKKDKQIIPQCTPEKEEAIMDALRHFKMI"
     gene            11743..12021
                     /locus_tag="VU534_001017"
     CDS             11743..12021
                     /locus_tag="VU534_001017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1513622.1"
                     /translation="MKKDKEVYDKVCEYLSPHLNKDMEVLELACWFRVITVIEANSYV
                     NIRSSRLLPKFKTQKINSWCAAYNIHFNNGYCKQHTNEFKDSLKSLIL"
     gene            12267..12485
                     /locus_tag="VU534_001018"
     CDS             12267..12485
                     /locus_tag="VU534_001018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001207345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU1513623.1"
                     /translation="MALNYKPLWIQLAKKGLKKTDVIAMAGLTTNVMAQMGKDKPITF
                     KNLERICKALSCTPNDIISFEDNFSDEE"
     gene            12878..13903
                     /locus_tag="VU534_001019"
     CDS             12878..13903
                     /locus_tag="VU534_001019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000790748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-siderophore ABC transporter
                     substrate-binding protein"
                     /protein_id="HEU1513624.1"
                     /translation="MKNKFFLIAILAMCIVFSACSSNSVKNEENTSKEHAPDKIVLDH
                     AFGQTILDKKPERVATIAWGNHDVALALGIVPVGFSKANYGVSADKGVLPWTEEKIKE
                     LNGKANLFDDLDGLNFEAISNSKPDVILAGYSGITKEDYDTLSKIAPVAAYKSKPWQT
                     LWRDMIKIDSKALGMEKEGDELIKNTEARISKELEKHPEIKGKIKGKKVLFTMINAAD
                     TSKFWIYTSKDPRANYLTDLGLVFPESLKEFESEDSFAKEISAEEANKINDADVIITY
                     GDDKTLEALQKDPLLGKINAIKNGAVAVIPDNTPLAASCTPTPLSINYTIEEYLNLLG
                     NACKNAK"
     gene            13893..14900
                     /locus_tag="VU534_001020"
     CDS             13893..14900
                     /locus_tag="VU534_001020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001244688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEU1513625.1"
                     /translation="MRNKKQINLGIIFIICLGLLITIFLSLKLGTKEINIRDFLAAFG
                     MGNTNDDFIKSIIYKRIPRTIFAILAGSSLAISGVLMQSVTRNPIADPGILGINTGAS
                     LSVVIGLSFLGISSSISHISFAIIGGLVSAIFVYAIAVSGKAGLTPIKLALSGTCVSM
                     ALSSFVSFLILPNNNVLDKFRFWQIGSLGAATLSSISTLLPFIILGHLIAIFISSDLN
                     ALAMGDEMAVGLGVNVNRIRSLAIIASVLLCSSITAIGGPIGFVGLIVPHFCGLFISK
                     DIRTMTISSSFIGAELLLICDIIGRMLGKPGEIEVGIITAIIGGPVLIYVTMKNRGVN
                     N"
     gene            14900..15907
                     /locus_tag="VU534_001021"
     CDS             14900..15907
                     /locus_tag="VU534_001021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEU1513626.1"
                     /translation="MQNLIIGIQKRKNRITLFSSLFLLIIISLSFFILLIGDESYSFS
                     TLIKVLNSETVPGASFSIMEIRLPKLLAGIIAGWSFGLAGFIFQTMLRNPLASPDIIG
                     VTSSSSIAAVFCILVLKTNSLTTGIISITCGLTSSLILFLLAKKDGFSAARLIILGIG
                     FQAVTRAGTSFLLLKVARYELQEVMRWLSGSLSFTKLDDIPLVLIVSIIATILVLFFN
                     KRLEIIELGEEIAIGLGANPELSRLVLIFCAVSLTAFSTSITGPIACISFLAGPIALN
                     IGKKRSPILAGLVGILLVLLSDIFSQNILPARYPVGVVTGLLGSPYLIYLLIKMNRRN
                     I"
     gene            15907..16701
                     /locus_tag="VU534_001022"
     CDS             15907..16701
                     /locus_tag="VU534_001022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000677523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU1513627.1"
                     /translation="MKGLWSNNLTCGYDEKIILENINIKIPEEKISVIIGSNGCGKST
                     LIKTLSRLIKPLEGEVLLDNKSINSYKEKDLAKHIAILPQSPIIPESITVADLVSRGR
                     FPYRKPFKSLGKDDLEIINRSMVKANVEDLANNLVEELSGGQRQRVWIALALAQDTSI
                     LLLDEPTTYLDISYQIELLDLLTDLNQKYKTTICMILHDINLTARYADYLFAIKEGKL
                     VAEGKPEDILNDKLVKDIFNLEAKIIRDPISNSPLMIPIGKHHVNS"
     gene            17089..17478
                     /locus_tag="VU534_001023"
     CDS             17089..17478
                     /locus_tag="VU534_001023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEU1513628.1"
                     /translation="MPKRYLLDGKTPRISATNIDNGILGYYEDIDDKNYRVFENFISV
                     SFLGAVFYHKYKASLDMKIHCLKLKNKELNKEVAFYLTSIIRQALKNTEYKDQISSTV
                     LPDIKIKLPIDSRGTPDWNYMERYRDR"
     gene            17444..17758
                     /locus_tag="VU534_001024"
     CDS             17444..17758
                     /locus_tag="VU534_001024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001835032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1513629.1"
                     /translation="MGITWKDIEIDKEREGEIDKKSTPIFYGEFKNVRLSKEEYKNLK
                     EKLNSHTDIMINKLSRYMESSGKTYQNHYVTILKWYEEDKDKLRQKGLNKKMNYDVGE
                     SL"
     gene            18442..18603
                     /locus_tag="VU534_001025"
     CDS             18442..18603
                     /locus_tag="VU534_001025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005761276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1513630.1"
                     /translation="MDNDWNGLADLIANLIAKYAGALDLDNLPDPTPAKNQEMKNSFD
                     MAKTQIETD"
     gene            18695..20374
                     /locus_tag="VU534_001026"
     CDS             18695..20374
                     /locus_tag="VU534_001026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEU1513631.1"
                     /translation="MSKEKIKVYLYTRVSTSIQIEGYSLEAQKSRMKAFAIYNDYEIV
                     GEYEDAGKSDKSIEGRIQFNRMMEDIKSGKDGVSFVLVFKLSRFARNAADVLSTLHIM
                     QDYGVNLICVEDGIDSSKDAGKLMISVLSAVAEIERENISIQTMEGRIQKAGEGKWNG
                     GFAPYGYKLEDGKLFINEEEAVAIRTIFDQYVNTTIGANGISKYLENHGIRKIPRQNG
                     KNPLFDAGLIRKILKNPVYNGKIAFGRRTLEKVHGTRNEYKQVEQDEYLISEGIHEAI
                     VSDEVWQAAQVKLKSQAKKYEHVNKGKDTRTHLLSGIVKCPICGVGMFGNKCIKKKKD
                     GTKYKDFYYYGCNHRQMIRGNKCTFSKQIREELLDDAVAEVIVKIVSNPKFASMMQEK
                     INMKVDTSEIEKEIDNYQKELRKSHSTKFKLIEEIDNLDVEDKHYKRRKQDLDDRLYR
                     MYDKLDELESSLIDAKAKKQTIEAEKLTGDNIYKVLIYFDKLYKVMNDVERRQLISAL
                     ISEIQVYEEKQSNGQWLKSITFKLPIIEENLNIGLDNDEQVECVSLLEKRS"
     gene            20642..21208
                     /locus_tag="VU534_001027"
     CDS             20642..21208
                     /locus_tag="VU534_001027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1513632.1"
                     /translation="MVILELYQNDYSKDLVAFDSIEDGKAFVAQIPGYTLETEDGFEV
                     EYFNPKNIPDYMEIIFNGNIVPLSKFMFDPEENVNIIWKEISNLSLKNDRVIEGYSKI
                     DAYVVNNHEVKAYVETRETNYRKAKDFLESRGYEIDRSFFGSEDGEAILYRKKGIEVW
                     HFLCHLDPMFVEIEDVEGYVKEEVGEIQ"
     gene            21530..21718
                     /locus_tag="VU534_001028"
     CDS             21530..21718
                     /locus_tag="VU534_001028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopG family transcriptional regulator"
                     /protein_id="HEU1513633.1"
                     /translation="MATDKNRIMISLDDKNLEKLENLVEDARDRRGMRLTKSQVIELL
                     LNTVDYFDDIMGAIYSKK"
     gene            21780..22538
                     /locus_tag="VU534_001029"
     CDS             21780..22538
                     /locus_tag="VU534_001029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HEU1513634.1"
                     /translation="MVVYIRQSKLPSEVSINKYNAQVGAYLQGEEVILYQSFSEIKEL
                     TSEDIVVDYIMETRALLKMMGLNVPVHDYPIELKEFYGRKIYAGILGEIVNIPDNWGK
                     FIKPKAGSKVFTGRVVNGTHDLIGIGLPFDYPIWISEVVEFIAEWRCFVLDGRVLDVR
                     PYTGDYHAQFDASVIDEAISCWKDAPIAYGLDIGVTRDGRTLVVEVNDGYALGNYGLS
                     PLKSINFHRARWKEMVKPYFEKNEIFKIQQDVIF"
     gene            22596..23450
                     /locus_tag="VU534_001030"
     CDS             22596..23450
                     /locus_tag="VU534_001030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000900021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribosylglycohydrolase family protein"
                     /protein_id="HEU1513635.1"
                     /translation="MLGAIIGDIVGSVYEWNNIKTKDFPLFRKDCFFTDDTVMTCAVA
                     EAIMNGGQKDDFIDAMKKYGRMYPNADYGARFNAWLNSDNREPYNSFGNGSAMRISPC
                     AWIMDCGFYAKTGIWPSSRGLTSLSAEVTHNHPEGVKGAMATADAIFLCRFYFGGYCR
                     EYEQSINDNPTECKRRIKDYIEKEYDYNLSQTLDEIRPNYRFNETCQETVPQAIIAFL
                     ESRDFEDAIRNAISLGGDSDTLAAITCSIAEAAYGIPDWIKDKAYSYLDEPLKDVVRR
                     WENRIKAY"
     gene            23562..24446
                     /locus_tag="VU534_001031"
     CDS             23562..24446
                     /locus_tag="VU534_001031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HEU1513636.1"
                     /translation="MKKAMVIINPTSGGEKALDYKEKLENKAKEYFEYVETKITEKAL
                     DATHFAEEASREQYDAVVVFGGDGTVNEVISGIDERDYIPKLGIIPGGTGNLITKLLE
                     INQDIDGAIDELDFDLTNKIDIGKANDNYFGYIFSIGSLPEAIHNVEIEDKTKFGILT
                     YAVNTMKSVMTDQVFNIKVETENGNYVGEASHVLVLLTNYFADKKIFEENKDGYANIL
                     ILKDASIFSKLSVIPDLLKGDVVANDNIEYIKARNIKISSDSELESDVDGDKSDNLPV
                     EIKVLAQRVEVFSKPKED"
     gene            24609..24971
                     /locus_tag="VU534_001032"
     CDS             24609..24971
                     /locus_tag="VU534_001032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001867177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha amylase N-terminal ig-like
                     domain-containing protein"
                     /protein_id="HEU1513637.1"
                     /translation="MELSAIYHRPESEYDYLYKDKKLHIRIRTKKGDIESINLHYGDP
                     FIFMEEFYQDTKEMVKITSGTLFDHWQVEVSVDFARIQYLFELRDTEGQNILYGDKGC
                     VENSLENLHAIGNGFKLP"
     gene            24952..26348
                     /locus_tag="VU534_001033"
                     /pseudo
     CDS             24952..26348
                     /locus_tag="VU534_001033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845046.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 13 protein"
     gene            26434..26751
                     /locus_tag="VU534_001034"
     CDS             26434..26751
                     /locus_tag="VU534_001034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000995815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1513638.1"
                     /translation="MNCRGHETRQRIVRDFEVQPKAHIKLLANQQKHSDAGATIEDEY
                     YVFIAESKIDGKKEVIQCCMGAARDFLELINHKGLPLFNPLVGDSHVNNRQEYDNTGS
                     GNL"
     gene            26797..27078
                     /locus_tag="VU534_001035"
     CDS             26797..27078
                     /locus_tag="VU534_001035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000266233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1513639.1"
                     /translation="MWLIILWNAKPDTPLFNFKDEVIKYKTYEPFESSIKRVNTTIKN
                     GSKGKTLTEMINGYRADNDIRDEICNFNILKNKIRDMKNQQGNTMESYF"
     gene            27523..27999
                     /locus_tag="VU534_001036"
     CDS             27523..27999
                     /locus_tag="VU534_001036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003042293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU1513640.1"
                     /translation="MIGKNIKSLRKTHDLTQLEFARIVGISRNSLSRYENGTSSVSTE
                     LIDIICQKFNVSYVDIVGEDKMLNPVEDYELTLKIEIVKERGANLLSRLYRYQDSQGI
                     SIDDESNPWILMSDDLSDLIHTNIYLVETFDEIERYSGYLDGIERMLEISEKRMVA"
     gene            27999..28760
                     /locus_tag="VU534_001037"
     CDS             27999..28760
                     /locus_tag="VU534_001037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxin PezT"
                     /protein_id="HEU1513641.1"
                     /translation="MEIQDYTDSEFKHALARNLRSLTRGKKSSKQPIAILLGGQSGAG
                     KTTIHRIKQKEFQGNIVIIDGDSFRSQHPHYLELQQEYGKDSVEYTKDFAGKMVESLV
                     TKLSSLRYNLLIEGTLRTVDVPKKTAQLLKNKGYEVQLALIATKPELSYLSTLIRYEE
                     LYIINPNQARATPKEHHDFIVNHLVDNTRKLEELAIFERIQIYQRDRSCVYDSKENTT
                     SAADVLQELLFGEWSQVEKEMLQVGEKRLNELLEK"
     gene            28788..29944
                     /locus_tag="VU534_001038"
                     /pseudo
     CDS             28788..29944
                     /locus_tag="VU534_001038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001213952.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            30776..31132
                     /locus_tag="VU534_001039"
     CDS             30776..31132
                     /locus_tag="VU534_001039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000817622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1513642.1"
                     /translation="MKRDVRDIRKQFRLTEAEEKQILALMRERGETNFSDFLRKSLLS
                     SDLQKQMETWFALWQSQKLEQISRDVHEVLILAQSERQVTQEHVSILLTCVQELIQEV
                     ANTIPLSKEFREKYMR"
     gene            31137..31502
                     /locus_tag="VU534_001040"
     CDS             31137..31502
                     /locus_tag="VU534_001040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000263054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
                     /protein_id="HEU1513643.1"
                     /translation="MEHRYRTNLKKVFLSDSELNQLNINIDQSGCKSFSEYARRTLLD
                     PGMNFITIDTNGYQDLVFELKRIGNNINQIARSVNQSQLISGEELQELKKGIGELIKE
                     VDKEFNLQAQKLKEFHGHH"
     gene            31489..33312
                     /locus_tag="VU534_001041"
     CDS             31489..33312
                     /locus_tag="VU534_001041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002917262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HEU1513644.1"
                     /translation="MVITKHFAIHGKSYRRKLIKYILNPEKTNNLALVSDYGMKNFLD
                     FPSYEEMVQMYHENFISNDTLYDFRHDRMEENQRKIHAHHIIQSFSPEDHLTPEQINR
                     IGYETVKELTGGKFRFIVATHVDKDHLHNHIIINSVDSNSDKKLKWDYKVERNLRMIS
                     DRFSKIAGAKIIENRYSHQRYEVYRKTNHKYELKQRLYFLMEHSRDFEDFKKNAPLLH
                     VEMDFRHKHATFFITDSTMKQVVRGKQLNRKQPYTEEFFKNYFAKREIESLMEFLLLK
                     VENMDDLLQKAKLFGLTINPKQKHVSFQFAGVEVKETELDQKNLYDVEFFQDYFKNRK
                     DWQAPETEDFVQLYQEEKLSKEKELPSDEKFWESYQEFKSNRDAVHEFEVELSLNQIE
                     KVVDDGIYVKVKFGIRQEGLIFVPNMQLDMEEDKVKVFIRETSSYYVYHKDAAEKNCY
                     MKGRTLIRQFSYENQTIPLRRKATVDMIKEKIAEVDALIELEVENQSYVTIKDELVHE
                     LAASELRINELQERMSTLNQVAEYLLASVESKQEMKLNLSKLNITENISANIVEKKLK
                     SLGNQLELERGRYEKMVVRLDKFINRLNTGLSKGDGIDFQK"
     gene            33426..34292
                     /locus_tag="VU534_001042"
     CDS             33426..34292
                     /locus_tag="VU534_001042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000537001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU1513645.1"
                     /translation="MGTLLATRLKNRRKELKMSQRELAEGICKQGQISRLESGEFTPG
                     ADFLHALAKKLKVSMDYFFDEQVVEEVNELSEFKKLAQTFITNRNYESLKYIYELENV
                     KAHRLSLADKFYMEWIKSLIDFYFYGQKEEAITRLENMLPQLNVSDLNYLQVSNTLFN
                     FYYDIEDLERFNEIRDKLEHQVNQLNLNTIEELELSIKFNYNVCRYLWLQKNIEEAIT
                     KITATIKQCKEYRTTYLLADLYLLMGSVSENFSSKSSVKEYFETAHFLYKLEENMSMA
                     LKVEHYFADITE"
     gene            34883..35134
                     /locus_tag="VU534_001043"
     CDS             34883..35134
                     /locus_tag="VU534_001043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000098314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1513646.1"
                     /translation="MSSQMKAFLNELQGNMEVVGEFFDNPEKVIRKFGIVGREKEALL
                     IRDLNDMDDYALSIQNSVASPSGAHSSTCHFVRQDLQSA"
     gene            35363..35665
                     /locus_tag="VU534_001044"
     CDS             35363..35665
                     /locus_tag="VU534_001044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000792536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1513647.1"
                     /translation="MKNKYDVKRIIPDELSESLDIFLKNYSETGLSDYNTYLFYGFIL
                     KSYKLPRENRYSIKLLVKELQNRGLKVTLIINIYYHALNCLALNDGLKIYGEDFLI"
     gene            35662..37008
                     /locus_tag="VU534_001045"
     CDS             35662..37008
                     /locus_tag="VU534_001045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein kinase"
                     /protein_id="HEU1513648.1"
                     /translation="MNYEKYLNYLDYETEIEDAYHNLLLEYKISDNFSDEHWLYNLPS
                     NITQSKGFKIHLSASILNANLVAKKFFDFIFSREKKINFKILVSIKELSLQNTGLNGY
                     SQVGKFITIYPKDNKEFQRLLHKLEILYKGVKGVNIPSDFRFQLSEVVYYRYGEFVKD
                     STFKDKRDKKIPSNVNVPIRDYYIPRYNTIPDQYIILEVISKNAKGGVYKVFNTQKRV
                     YSLLKEASDLSLVDFTNRDSVNRLINEREILVELEKEEFTPKVFNDFYIKNSYFVEFE
                     FIIADKLSEYNMVSGSYDWFLTLIDYMEIINSKYNLSYRDLSFNNILIDNRNNIYIID
                     FEHALRKETQIEEKKLPLFGTPGFYETNLNLLNNQPEDIMGLVLLLYWSQNLDDFNVF
                     SKMSFLEAMEYAMNFNSRRLDTLDKSDWLYDIYKKAFNYKYDTFSELKKDFIEVLK"
     gene            37022..37939
                     /locus_tag="VU534_001046"
     CDS             37022..37939
                     /locus_tag="VU534_001046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000995574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU1513649.1"
                     /translation="MNCFLKMNNVSVRYDDVIALKDITLQINKGDFIGLLGSNGAGKS
                     TLINSIVGFQEIYLGEIEYCDKDLIVSSQPFAHLGFTPQTTVIDFYTTVKDNVILGLN
                     LAGKFGKNAEKLCQIALEIVGLADKKNNLVETLSGGQLQRVQIARAIAHNPDFYILDE
                     PTVGLDTESAEKFLMYLKDKSLEGKTIIISSHDINLLEKFCKKILFLQNGSISFFGDM
                     RDFVDNSTIKLNFSMQNRISRYQIEFLENFRFKVHIEDNDSFTIEVPIEEKILDVINE
                     VGKACEIKNFSTSKLTLQESYLQRIGGEK"
     gene            37936..38736
                     /locus_tag="VU534_001047"
     CDS             37936..38736
                     /locus_tag="VU534_001047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000642567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU1513650.1"
                     /translation="MKADQLRHKSDLGLRGLAIIAKNEIIAFFRSKGLIISQFLQPIL
                     YVVFIIIGLNSSIKNIQFNDIKTSYAEYTIIGVIALLIIGQMTQVIYRVTIDKKYGLL
                     ALKLCSGVRPLYYILGMSIYSILGLIVQEIIIYIITLAFEINIAMDRFFYTVLLSIVV
                     LLFWDSLAILLTMFINDYRRRDIVIRFVLTPLGFTAPVFYLIDSAPSIVRWIGQLNPL
                     TYQLTILRNFYFKNSTTLELVFLLLTSLLVLISVSFIIPKIKLILIER"
BASE COUNT        13472 a         5905 c         7697 g        11682 t
ORIGIN      
        1 catgaccgaa tgaaggatca tggatttttc ttattttcct aaacagaatt ggctaaagag
       61 ttgggtgatg agttcatctg gagcagcatc tccagtgatt tctcctagaa tttcccaagt
      121 acgggtcaag tcaacttgaa gcaagtcaac tggcatccct agttcaagac cttggttaac
      181 agcttgtagg ctttcaacgg ccttctcaat caaggaaatg tgacgggcgt ttgacaagta
      241 ggtagcatct tgctcaacca aaccagcatt ttcaaagaag aggttgttga ttctctcttc
      301 gattttatcg atgttttgat ttttaagaac tgaaatgcgg atgacatctt caggtagttc
      361 cgaagtttca atcgtttcag gcaggtcagt tttgttaaga agaataatgc gattagtctc
      421 ctgactgatt tctaggagtt ggcgatcttg ggcggttagt ggttcactag cgtttagtac
      481 tagcagaact aggtcagctt ccttaagagc ttttttcgaa cgctcaactc caatttgttc
      541 aacgatatca tccgtttcac gaataccggc tgtatcaatc aatttgagag gtacaccatt
      601 gatgttgacg tactcttcga tgacatctcg tgttgtccca gcgatatctg ttacgatagc
      661 cttgtcctca cgcaagaggt tgttgagaag gcttgatttc ccaacgttgg gacgtccaat
      721 gatagccgtt gaaattcctt cacgaaggat tttaccacga cgtgctgtcc taaggagttt
      781 ggttagtaat tgctcaaact ccattgtctt ctctcggaca acagcagtag tggcttcctc
      841 aacatcgtca tactcaggat agtcgatatt gacctcaact tgggcaagtg tattgaggat
      901 ttcttgacgg gtattgttaa tgaggtcaga aagggagccg tctaattgtt tgaccgcaat
      961 gttcatggcc ttgtcagtct tggcacggat gatatccatc acagcctctg cctgtgtcaa
     1021 gtctacgcga ccgtttaaaa aagcacgttt ggtaaattca ccaggttctg ccaaccgagc
     1081 cccttcacga atagctagct ggagaatttc attggtcacc gcaatcccac cgtgggtgtt
     1141 aatctcgata atatcctcac gagtgaaggt ctttggagac ttcatagccc caaccataac
     1201 ctcgtccatg actttaccag tcagaggatc aataatgtga ccgtagttga gagtgtggct
     1261 ggcaaccttg ttcaagtctt ttcctttaaa aatcttttgc gcaatagcaa aactgtctgt
     1321 tccgctcagg cggacaatac caatagcccc ttcacctagt ggagtagaga tagcagcgat
     1381 ggtatcaaat tcacgtgtaa tcataatgtt tcctttaatt aatagctctt ttcttggaaa
     1441 ttctccaagt ttcttttcaa attgtaacaa atttaggata tttcttcaat gaatgctact
     1501 tggagattga aaaagcctaa gcaattctgc ttaagctagc ttatttagta cgcatttccc
     1561 cttgtgggaa gtaagttcct tctggcatgt cgttgatgat gacatggaca gcagattgag
     1621 gggctccagt gttgcggaca actgcttccg ttacttcctt agcaagagct ttcttttgct
     1681 cgagcgtgcg tccttcaaat aaatcgatgc gtacaaatgg cataatagct tcctccacta
     1741 gtttttgatt tcttctattt taccacattt tgccgtttaa agcttaagaa aattatgata
     1801 tactagaatg tagcaaaaat ttagaaatgg acgtgaagca agaaacatgg cacagttgta
     1861 ctatcgttat gggaccatga actctggtaa aacgattgag attctcaaag tggcctataa
     1921 ctacgaggag caaggaaaag gtgttgtgat tatgacctcg gctctggata cgcgtgacgg
     1981 cgttggctat gtgtcgagtc gaattggcat gaaacgccct gcccttgcga ttgaggaaac
     2041 aacggatatc tttggctata tccgagacct accagaaaaa ccttactgtg ttttggtcga
     2101 tgaagcccag tttctcaaac gccaccatgt ttacgaccta gctcgtgttg tggacgagtt
     2161 agacataccc gtcatggctt ttggcttgaa aaatgacttt cgcaatgaat tgttcgaagg
     2221 ttccaaatat ctcttgcttt tagcagacaa gattgacgaa atcaagacca tctgtcagta
     2281 ttgcaagaaa aaggcgacca tggtgttgcg aacacaggat ggactgcccg tttacgatgg
     2341 agaacagatc cagattggtg gtaacgaaac ctatatctca gtttgccgta aacattattt
     2401 tgcgccaatg ataacctcta acaaggagca aaactatgac aattgaacta agagatgtta
     2461 caatggaaaa ttattttgat gttttaaatt tggatgtcaa ggaatatcaa aaacaattca
     2521 ttgcaaccaa cgcaattagt ttagctgaag catacgtcta cactaaaaat ggagattttg
     2581 tagctccatt ggcagtttat gataatgatg caattatagg ttttgtgatg atagcttatg
     2641 ataaaaagat cggaattagt agtggaaatt atttactatt tcgttttatg attgataaga
     2701 attttcaaaa tcaaggatat tttaaaccaa ttatggataa agtactagac tatgttcgaa
     2761 cagcgccagc aggtttaagc aataaacttt ggttgtctta tgaaccagaa aatgaacagg
     2821 caagattttg ttacctcagt tatggattta aagaaactgg ggaaatatcc gagaatgaag
     2881 tagtagcaat ctatgattta acaattgaga aataaggaga aaaaatgaac atctatgatc
     2941 aactacaagt tgtagaagac cgttatgaag aattaggaga attgctgagt gaccctgatg
     3001 tcgtttcaga caccaagcgt tttatggagc tttcaaaaga agaagcttcc aatcgtgaca
     3061 ccgtaatagc ctaccgtgag tataaacaag tccttcaaaa tatcgtcgat gccgaagaga
     3121 tgattaagga atcaggcgga gatgcggact tggaagaatt ggccaagcaa gaactcaaag
     3181 atgccaaggc tgaaaaagaa gaatatgaag aaaaactgaa aattttgctc cttccaaagg
     3241 atccaaacga tgacaagaat atcatccttg aaatccgtgg agcagctggt ggagacgaag
     3301 cggcactttt cgctggagat ttgctaacta tgtaccaaaa gtatgcggaa gcccaaggtt
     3361 ggcgctttga agtcatggaa gcctctatga atggtgtcgg tggttttaaa gaagtggttg
     3421 ctatggtttc aggtcagtct gtatactcta agcttaagta tgaatcaggt gcccaccgtg
     3481 tgcaacgtgt tcctgtgaca gaaagccaag gccgtgttca tacttcgaca gcgacagttc
     3541 ttgttatgcc agaagttgaa gaggttgaat acgacattga tccaaaagac cttcgtgtcg
     3601 acatctatca cgcctctggt gctggtggac agaacgtcaa taaggttgcg actgccgttc
     3661 gtatcgttca cttgccaacc aatatcaagg ttgagatgca ggaagaacgt acccagcaga
     3721 agaaccgtga gaaggccatg aaaatcatcc gtgcccgtgt tgctgaccac tttgctcaga
     3781 ttgctcaaga tgagcaggac gctgagcgta agtcgacaat cggtactggt gaccgttcag
     3841 aacggatccg aacttataac ttcccacaaa accgtgtcac agaccaccgt atcggcttga
     3901 ccctccaaaa actagatacg attttgtctg gtaaattgga cgaagttgtg gatgccttgg
     3961 tgctttatga ccaaacacaa aaactagaag aattaaacaa ataatgaaat tagctcaatt
     4021 attttcaaat tttgaagaag agttgataag acaaggagag gaagcggaaa gcctctcttt
     4081 tgtctatcgt agtctgaaaa atctatcttt tacagacttt atttttgccc tccagcagga
     4141 ggtgacaaca gaggaagaaa aacaatttgt agaagatatt taccagcaac tagcagctca
     4201 caagccagct cagtacatca ttggacaggc agatttttat ggaatgcatt taaaggtgga
     4261 tgaacgggtt ttgattcctc gtccagaaac agaggagttg gtggagctta tcctggctga
     4321 aaatcctgtg aaaaatctta tggtcctaga tatcggaaca ggtagtggag ctattgctct
     4381 cgctctagca aaaaacagac cagattggtc agtgacggca gcagatattt cccaagatgc
     4441 tttagatgta gctagcgaaa atgctaaaaa tcaaaatctt caaatatttt taaaaaaatc
     4501 tgactgtttt acagaaattt ctgaaaaata tgatataatt gtttccaatc caccctatat
     4561 ctctcgtgaa gatgagtcag aggtaggctt gaatgtcttg tattcggagc ctcatctagc
     4621 tctctttgca gatgaggatg gcctagctat ttaccgtaga attgcggaag atgcaaaaga
     4681 ctatctcaaa gatggtggta agatttacct tgaaattgga tacaagcaag gtcaaagtgt
     4741 tcctgaactt tttaggaaac atcttcctga aaagcgagta cgaacactca aggaccaatt
     4801 tggtcaagat aggatggttg tcgttgatga tggacaggat tagacaagag ttggaaaatg
     4861 gtggagctgt cgttttgcct acagagacag tttacggtct ctttgctaag gcgctagacg
     4921 aaaaagcagt tgaccatgtt taccagctta aacgtcgacg tagagacaag gcgctcaatc
     4981 tcaatgttgc ctctttagag gacatcttgt acttttcaaa gaatcagcca acttatcttc
     5041 aaaaacttgt agagatcttt ttaccaggtc ccttgaccat tattctcgaa gctaatgacc
     5101 gagttcccta ttgggtcaat tctggccttg caactgttgg atttcggatg cctagtcatc
     5161 ccattaccct tgatttgatt cgagagacag gtcccttgat tgggccgtct gccaatatct
     5221 caggtcaggc gagtggagtg acctttaatc aaattctaga ggattttgac caagaggttc
     5281 tgggtctgga agacgatgct tttctaactg gacaggattc aactattttg aatttgtcgg
     5341 gagacaaggt gaaaatctta cgtcaagggg ccattaagcg agaagatatt cttgctcggt
     5401 tgccaaagat ttcttttgag gaggaatgag atgctaagag atttaagaga aactgatgtg
     5461 aaagctatat gtgacatcaa ccaagaggct ttgggttata cttttagtcc agaggaaacg
     5521 gctagccaac tagctagact gtctcaggat tcccatcatt tcctacttgg ctatgaggat
     5581 gcagctaatc atgtcttact tggatatgtc cacgctgaag tttacgaatc actctattcc
     5641 aaagcaggat ttaatatctt agctttagca gtttcacctc aagcgcaagg tcaaggtatt
     5701 ggtaaaagtt tactacaagg gttggaagaa gaagcaaaaa gatgtggtta tgggtttatc
     5761 cgcttaaatt ctgccaatca tcgtctgggt gctcatgcat tttatgaaaa agttggctat
     5821 acttgtgata aaatgcagaa acggtttatt cgcatctgtt agtttgattt tcttattgta
     5881 aaatcaaact aatggactag tcacacaata aaggagaaga cctatgattt ttgacaaaga
     5941 tgattttaaa gcatatgatg ctgatctctg gaatgctatt gccaaagaag aagaacgcca
     6001 acaaaataat atcgagttaa ttgcttcgga aaacgtagtt tccaaggctg ttatggcagc
     6061 tcaagggtct atcttgacaa ataaatatgc cgagggttac ccaggacgcc gttattatgg
     6121 tggaactgat gtagtagacg ttgtagagac tcttgctatt gaacgcgcaa aagaaatttt
     6181 cggtgctaaa tttgccaatg ttcaaccaca ttcaggaagc caagctaact gtgcggctta
     6241 catgtccttg attgagccag gtgatacggt tatgggaatg gatttggcat caggtggtca
     6301 tttgactcat ggggctcctg ttagcttctc tggtcaaacc tacaactttg tttcttatag
     6361 tgttgatcct aaaacggaac tcttagactt tgatgctatc ttgaaacaag cccaagaagt
     6421 aaaaccaaaa ctgattgtag ctggtgcttc agcctattct caaattatcg atttttcaaa
     6481 attccgtgaa atcgcagatg ctgtcggtgc gaagctcatg gtggacatgg cccatatcgc
     6541 tggcttggtt gcggctggcc ttcatccaag cccagttcca tacgctcata tcacaacaac
     6601 aacgacccac aaaacccttc gtggacctcg tggtggtttg attttgacca atgacgaaga
     6661 acttgctaaa aaaatcaatt cagctatttt cccaggtatt cagggcggtc ctttagagca
     6721 tgttgtggcg gctaaggcag tttccttcaa agaagttttg gatccagcct tcaaggaata
     6781 tgctgccaat gtaattaaga acagcaaggc tatggcagat gtcttcttgc aagaccctga
     6841 tttccgtatt atttcaggtg gaactgaaaa ccatctcttc cttgttgatg tgactaaagt
     6901 tgtagaaaac ggcaaagttg ctcaaaactt gttggatgaa gtcaatatta ccttaaataa
     6961 aaactcaatc ccttacgaaa gcttgtcacc attcaagaca agtgggattc gtatcggagc
     7021 agcagccatt actgcacgtg gatttggtga agaagaaagt cgcaaagtgg ctgaactcat
     7081 cattaaaacc cttaagaatt cagaaaatga ggctgtatta gaagaagtga gaagtgcagt
     7141 caaagaattg acagatgcct tcccattata cgaggactaa aacttttatg gacatttata
     7201 ttaagaaagc cattattcac cagttcagtc cggatgatac cgaactgttc ttagcagata
     7261 agtttctcaa tattactcca aaaatcgaag aatacctgcg taaaaaaatt gaacatgtgt
     7321 attcagatga agccaagact gggattttcg aagaagaaaa tcccttcttc aatcatatta
     7381 cagacgattt gttggagaca tcagtaacgc tggctaatct ctggaaagag gagtttagca
     7441 tttctgaaaa tctcaagacc aatgacttga tttttgtgca attttctaaa gaaggtgtag
     7501 aacatttcgc tttcttgcga attgccctgc gggagacctt gacccacctc ggaggagaag
     7561 ttgataatcc aatcaagcta actcagaata acctgcctgg atttggaaca ggagctgatg
     7621 aggccttggt ggtcaatctt cagagtagca agtatcacct gattgaaaaa cgaatcaagt
     7681 acaacgggac ttttttgaac tatttttcag ataatcttct tgctgtcgct cctaagattt
     7741 ctcctaaaaa atctatcaag gaactggaaa aaacagccca gagaattgct aaatctttta
     7801 acacagatga ttttcaattt caatccaagg tcaaatcagc tattttcaac aacctagaag
     7861 aaagcaatga attgtcacct gagaaattgg ctaatgacct ttttgacaac aatctgacgg
     7921 ctcgtttgag ctttattgac caagtcaaag aagccgtacc agaacctgtt caatttgatg
     7981 aaattgatgc cagtcgccaa ttaaagaaat ttgaaaacca aaaactctcc ttatcaaatg
     8041 gaattgagct catcgttccc aataacgtct atcaagacgc cgagtctgtt gagtttatcc
     8101 aaaacgaaaa tggaacctac tctatcttaa tcaaaaatat cgaggatatc caaagtaaat
     8161 aatgtttaaa cgaattcgaa gagtgcttgt actagcagtc ttcctttttg ctggctataa
     8221 agcttaccgc gttcatcaag atgtcaaaca agtcatgacc tatcaaccca tggtgcgaga
     8281 aatattgagt gaacaagaca ccccagcaaa cgaagagctt gtgcttgcta tgatttatac
     8341 tgaaacaaaa ggaaaagaag gcgatgttat gcagtctagt gagtctgcaa gtggttccac
     8401 caacaccatc aatgataatg cctctagcat tcggcaaggc attcaaactc tgacaggcaa
     8461 tctctatctg gcgcagaaga agggggtaga tatctggaca gctgttcaag cctataattt
     8521 tggacctgcc tatatcgatt ttatcgccca aaatggcaag gaaaataccc tggctctagc
     8581 caaacagtac tctcgtgaga ctgttgcccc cttgcttggt aataggactg gaaagactta
     8641 tagttatatt caccccattt ccatttttca cggtgctgaa ctctatgtaa atggaggaaa
     8701 ctattattat tctagacagg tacgacttaa cctttacatc atcaaatgtt tcactctctt
     8761 ttcaacatct ggctagacca ggtgtttttg ttataagttt tctttaagat agatatatta
     8821 ctctaaagaa gtaaaggagg aaattcccta tgagaaagaa actctttctg actagcgctg
     8881 cgatcttgtg ggcagtaaca gctatgaata gcgtccatgc agcaacagat gttcaaaaag
     8941 ttatcgatga aacctatgtc caacctgaat atgtcctagg ttcctcccta tctgaagacc
     9001 aaaaaaatca aactcttaaa aaactgggct acaatgcctc aacagatacc aaagaactca
     9061 agaccatgac acctgatgtt tattctaaaa tcatgaatgt ggccaatgac tctagcttac
     9121 agttgtattc atcagccaag attcaaaagc taggtgacaa atcgccactt gaggtcaaga
     9181 ttgaaacacc agaaaatatc actaaggtga ctcaggatat gtaccgaaac gcagcagtaa
     9241 cgctgggtat ggaacatgcc aaaatcactg tagcagcccc tattccagtt acaggagaaa
     9301 gtgctttagc agggatttac tattcgctag aggctaatgg agccaaggtg ccacaagcta
     9361 ataaagattt ggctcaagaa gagctaaaag ctttgtcaga tatcaatgct gaaaacaagg
     9421 acaaatcagg ctatgatgct aataaattaa acgttgccct agctgatatc aagtcaggac
     9481 tcgccaaagc taaagaaagt aagggaaatc tgacagaaga agatatccgc aagattgttg
     9541 aagatacctt aaaaaattac aaacttgatc aggtcataac aggaaaccag atcaatatca
     9601 tcatcaattt tgccttgaat ctctcaaaga gtgatatcct cagcaatgca gatttcacta
     9661 aaaccctaaa tgaccttaaa caaagcatcg tatcacaagc tggcgacagt tttaaaaata
     9721 tcaaccttaa ctttgatgcg gataaggcgc tagaggacgg tggtaacttc ttaagctccc
     9781 tctggcaagc ccttgtcaac ttcttcaaga gttttggttc ttaagaaatt tcatggtata
     9841 atggatggta accgtaacgt tgccgtcttt tttgtcggcc aatagaaaga gaaaagaatg
     9901 ttaaagaaaa atgatattgt agaagttgaa attgttgatt tgacccatga aggggcagga
     9961 gttgccaagg tagatggttt ggtctttttt gtagagaatg ctttaccgag tgaaaaaatt
    10021 ctcatgcgtg tcctcaaggt caataaaaag attggctttg gaaaagttga aaaatacctt
    10081 gtccagtcac cacaccgtaa tcaagatcta gatttggctt acctgcgttc aggaatcgcg
    10141 gatttaggac acctttctta tccagaacag ctcaagttta aaaccaagca agtcaaggac
    10201 agtctctaca agattgctgg aattgcagat gtagaagttg ctgaaacgct tggtatggaa
    10261 catccagtca agtatcgcaa taaggcgcag gtgcccgttc gtcgagtgaa tggtgtcttg
    10321 gaaacaggat ttttccgtaa gaattcgcat aacctcatgc cccttgaaga tttctttatc
    10381 caggatcctg tcattgacca agtcgtagta gctcttcgag acctgctccg tcgttttgat
    10441 ttaaaacctt atgacgaaaa ggaacagtct ggattgattc ggaatcttgt ggtgcgtcgt
    10501 ggtcactatt caggacaaat catggtcgtt ttggtgacaa ctcgtccaaa agtttttcgt
    10561 gttgaccaat tgattgaaca agttatcaag cagttcccag agattgtgtc tgtcatgcaa
    10621 aatatcaacg accagaatac caatgcgatt tttggtaagg agtggcgcac tctttatggt
    10681 caagactata ttacggacca gatgttggga aatgacttcc aaatcgctgg cccagccttt
    10741 taccaagtca atactgaaat ggcggagaaa ctctatcaaa cagccattga ctttgcagag
    10801 ttaaaaaaag atgatgtgat tattgatgcc tattctggta ttggaaccat tggtttatca
    10861 gtcgccaagc atgtcaaaga agtctacggt gttgaactga ttccagaagc agtagagaat
    10921 agccagaaga atgcttcttt gaacaagatt actaatgccc actatgtctg tgacacggct
    10981 gaaaatgcca tgaagaaatg gctcaaggaa ggtattcaac caaccgttat cttggttgat
    11041 cctccacgca agggcttgac agaaagcttt atcaaagcaa gcgcccaaac aggagccgat
    11101 cgcatcgcct atatctcctg caatgtcgca accatggcgc gtgatattaa actataccaa
    11161 gagttgggat atgaattgaa gaaagtccag ccggtggatc tatttcctca aacgcatcac
    11221 gtcgagacgg tagcactttt gtccaaactc gatgtcgata agcacataag tgttgaaatt
    11281 gagctggatg agatggattt gacaagtgcg gagagcaaag caacatatgc tcaaatcaaa
    11341 gaatatgttt ggaataaatt tgaattaaaa gtttcgacat tatatattgc acagataaaa
    11401 aagaaatgtg gaatagaatt acgagaacat tacaacaagt ctaaaaagga taaacaaatt
    11461 attccacagt gtacacctga aaaagaagaa gccatcatgg atgctttgag acacttcaaa
    11521 atgatttaat agaaaagaat gacagtatat gactttctgc atttattaca ttcctacttg
    11581 gtataggaac agctattatt cctttcttgc aaggtatcaa ttagaaaata ggctcaatat
    11641 aaagattgat aggatcattt ttatatttaa aggagcgttg aaatgattga taaaggcaac
    11701 aaaaaatttt aggataaatt tgctaagttg tatgcctctt ttatgaaaaa agataaagag
    11761 gtttatgata aagtttgtga atatcttagt cctcatttga ataaagatat ggaggtgctt
    11821 gaacttgctt gttggtttcg tgtcataaca gttatagagg caaatagtta tgtaaatata
    11881 aggagttcaa gacttctacc aaagtttaaa actcaaaaaa taaatagttg gtgtgctgct
    11941 tacaatatcc attttaataa tggatattgt aagcagcaca ccaatgaatt taaagattct
    12001 ttaaagagtc ttattttgtg atgaaaattt aatatgtaaa tctcagacga tagaaattaa
    12061 aaactctatc gtctttttta tactcaaaat taggaggtaa aaatggtaag gataagaggt
    12121 cccacttaaa acaatttatg gcaaaataag gacggaataa cacaacaaat tctctaaaac
    12181 aaatcactaa atcaatgtaa gattgaatga aatcaatatt tatgctataa ttaaataaat
    12241 ttaatgaaga aaaaaagagg gatattatgg cacttaacta taaaccatta tggatacagt
    12301 tagcaaaaaa aggactaaag aaaacagatg taatagctat ggcaggactt acaacaaatg
    12361 ttatggcaca aatgggaaag gataaaccaa ttacatttaa gaatttagaa agaatatgta
    12421 aggctttatc ttgcactcct aatgatatta ttagttttga agataatttt agtgacgagg
    12481 aatagaaaat gactttaagg acagaagatc aagttaggga ttatgcaaga gaagtatagg
    12541 ctttaatgaa gttgaagaaa acatcaatca aggtactggt caaataacta cttttaatca
    12601 attaggcttc aagggatatt caaataagcc agatggttgg tatttaccta aaaatatgaa
    12661 tgatgtagca ataatccttg aaacaaaatc agaagaaaga gatattagca aacaaatttt
    12721 tattgatgag ttaatgaaaa atatagacat aatttaacta aaaataaaaa ctagatcctt
    12781 ttttgaaaaa attatattat taaatttgta actgtatcta ttgacaatga taattattat
    12841 cgatacaata gacttgaaat atgtttaagg agtttttatg aaaaacaaat tttttctaat
    12901 agctatttta gctatgtgta tagtttttag cgcttgttct tctaattctg ttaaaaatga
    12961 agaaaatact tctaaagagc atgcgcctga taaaatagtt ttagatcatg ctttcggtca
    13021 aactatatta gataaaaaac ctgaaagagt tgcaactatt gcttggggaa atcatgatgt
    13081 agcattagct ttaggaatag ttcctgttgg attttcaaaa gcaaattacg gtgtaagtgc
    13141 tgataaagga gttttaccat ggacagaaga aaaaatcaaa gaactaaatg gtaaagctaa
    13201 cctatttgac gatttggatg gacttaactt tgaagcaata tcaaattcta aaccagatgt
    13261 tatcttagca ggttattctg gtataactaa agaagattat gacactctat caaaaattgc
    13321 tcctgtagca gcatacaaat ctaaaccttg gcaaacttta tggagagata tgattaaaat
    13381 tgattcaaaa gccttaggta tggaaaaaga aggtgatgag ttaatcaaaa atactgaagc
    13441 tcgtatatcc aaagaattag aaaaacatcc agaaatcaaa ggaaaaatca aaggaaaaaa
    13501 agtattattt actatgatta atgctgcaga tacatcaaaa ttctggattt atactagcaa
    13561 agatccaaga gcaaattatt taacagattt aggtctagtt ttccctgaat cattaaaaga
    13621 atttgagagt gaagatagtt ttgcaaagga aatttctgca gaagaagcaa ataagataaa
    13681 tgatgctgat gtaatcataa cttatggtga tgataaaact cttgaagctt tacaaaaaga
    13741 tcctctttta ggtaaaataa atgcaattaa aaatggtgcc gttgctgtaa ttccagataa
    13801 tacaccgtta gcagcctcat gcactccaac accactttca ataaactata ctattgaaga
    13861 atacctaaat cttttaggaa atgcatgcaa aaatgcgaaa taaaaaacaa ataaacctag
    13921 gcataatttt tataatctgc ctaggtcttc ttattacaat atttttgtca ttaaagcttg
    13981 gaacaaaaga aattaatatc agagattttt tagcagcttt tggaatgggt aatacaaatg
    14041 atgattttat taaatcaatt atatataaaa gaatacctag aactattttt gcaattttag
    14101 caggttctag tcttgccata agcggtgtat tgatgcaatc agttactaga aacccaatag
    14161 ctgatccagg tatactcggt ataaacacag gagcaagtct tagtgtagta attggtcttt
    14221 cttttttagg aatttcatca agcataagcc atataagttt tgcaatcatt ggtggcttag
    14281 taagtgcaat ttttgtatac gcgattgctg taagcggaaa agcaggcctt acccctataa
    14341 aacttgcctt atcaggaact tgtgttagta tggctttaag cagttttgta agttttttaa
    14401 ttttaccgaa taataacgtc ttagacaaat ttagattttg gcaaataggt agccttggag
    14461 cagctacatt atcttctata tctacactac taccttttat aattttaggt cacttgatag
    14521 ctatatttat ttcatcagat ttaaacgctt tagctatggg tgatgaaatg gctgttggtc
    14581 ttggagttaa tgttaatagg ataagatcac ttgcaataat tgcaagtgtg cttttatgtt
    14641 caagtattac tgcaattggt ggacctattg gcttcgtagg tcttatagtt cctcactttt
    14701 gtggcttatt tataagcaaa gatatacgca caatgaccat ttcttcatct tttataggtg
    14761 cagagctctt gcttatatgt gatataatcg gccgtatgtt aggtaaacca ggtgaaattg
    14821 aagtagggat aattactgca ataatcgggg gtccagtact tatttatgta actatgaaaa
    14881 atagaggggt taataactaa tgcaaaattt aattataggt attcaaaaaa gaaaaaatag
    14941 aataacacta ttttcctcac tatttttatt aataataatc agtctatcat ttttcatttt
    15001 acttatcgga gatgaaagtt attctttttc aactttgatt aaagtcttaa atagtgaaac
    15061 tgttcctgga gctagttttt cgattatgga aattagatta ccaaaattat tagcaggaat
    15121 tatagctggc tggtcttttg gattggcagg atttatcttt caaactatgt taagaaatcc
    15181 tcttgcaagt cctgatataa tcggtgtcac aagttcttca tctattgcag cggtcttttg
    15241 catattggta ttaaaaacaa atagtttaac tactggaatt atttcaataa cttgtggact
    15301 aacatcatct ttaatattat ttttactagc taaaaaagat ggtttttcag cagcaagact
    15361 gataatatta ggtattggtt ttcaagctgt cacaagagca ggcacctcat ttttattgtt
    15421 gaaagtagca agatatgaat tacaagaagt tatgagatgg ctcagtggct ctttatcttt
    15481 tacaaagtta gatgacatac ctcttgttct aatagtaagt attattgcta ctatattagt
    15541 tttatttttt aataaaagac tagaaattat tgaacttggt gaagaaatag caatcggact
    15601 tggagcaaat cccgagcttt caaggcttgt tttaattttt tgcgctgtat ctttaactgc
    15661 tttttctact tcaattacag gaccaatagc ttgtatatct tttttagctg gtcccatagc
    15721 cttaaatatt ggcaagaaaa gaagcccaat attagctgga ttggttggaa ttttactagt
    15781 tttgttatca gacatattct ctcaaaatat tttaccagct agatatccag taggtgttgt
    15841 aactggcttg ttaggttcac catacttaat atacttacta ataaaaatga acaggaggaa
    15901 tatataatga aaggtctgtg gtcaaataat cttacctgcg gttatgatga aaaaataatc
    15961 ttggaaaata taaatataaa aatacctgaa gaaaaaatat cagttattat tgggtcaaat
    16021 ggttgtggga aatcaacact cattaaaacc ttgtctcgac ttataaagcc attagaggga
    16081 gaagtattgc ttgataataa atcaattaat tcttataaag aaaaagattt agcaaaacac
    16141 atagctatat tacctcaatc tccaataatc cctgaatcaa taacagtagc tgatcttgta
    16201 agccgtggtc gtttccccta cagaaagcct tttaagagtc ttggaaaaga tgaccttgaa
    16261 ataataaaca gatcaatggt taaggccaat gttgaagatc tagcaaataa cctagttgaa
    16321 gaactttctg ggggtcaaag gcaaagagta tggatagctc tagccctagc ccaagataca
    16381 agtatcctac ttttagatga gccaactact tacttggata tctcatatca aatagaacta
    16441 ttagacctct tgactgatct aaaccaaaaa tataagacaa ccatttgcat gattttgcac
    16501 gatataaatc taacagcaag atacgctgat tacctatttg caattaaaga aggtaaactt
    16561 gttgcagagg gaaagcctga agatatacta aatgataaac tagttaaaga tatctttaat
    16621 cttgaagcaa aaattatacg tgaccctatt tccaattcgc ctctaatgat tcctattggc
    16681 aagcaccatg ttaactctta ataattgaat attggaattc atttaaaagt cgcaaatttt
    16741 gaactgaccc tcaaaagtta ggccaaaaaa ctaactaaag gaggtcagtt ttttaatggc
    16801 aaatacagca cagaatttaa gataaaatta gtaaaagaat atcatgaatg aaaaatagga
    16861 tatagagaat aacagcaata ttaaaaagat caggactgat aataaacaaa aagaaagtac
    16921 aacgactagt tcaaaagcta aaacttcaag taaaaagtta ttcaagaaaa tctagaaaat
    16981 actcatccta caaaggacag gtaggaaaaa tatcagacaa caaaataaaa agaaatattt
    17041 attaccgaaa aaaaggggaa atcgagttaa gtaccaacag gctcatctat tccaaaaaga
    17101 tatttactcg atggaaaaac tcctagaatt agtgctacaa atattgacaa tggtatctta
    17161 ggttactacg aagatataga tgataaaaat tatagagttt ttgaaaattt tatatctgtt
    17221 tcatttttag gagcagtctt ttatcataaa tataaagcaa gcctagatat gaaaattcat
    17281 tgtttaaaat taaaaaataa agaattgaat aaagaagtag cattctattt aacttcaatt
    17341 attaggcaag ctttaaaaaa tactgaatat aaagatcaaa tatctagcac agtattgcca
    17401 gatatcaaaa ttaaattacc gatagacagt agaggtactc cagattggaa ttacatggaa
    17461 agatatagag atagataaag agagagaggg agagatagat aaaaagtcca cccccatttt
    17521 ttatggagaa ttcaaaaatg taaggttaag caaagaagaa tataaaaatc taaaagaaaa
    17581 attaaactca cacacagata taatgataaa taaactatcc agatacatgg aaagcagtgg
    17641 taagacctat caaaaccact atgtgacaat cttaaaatgg tatgaagaag ataaagacaa
    17701 actaagacag aaaggtttaa ataaaaaaat gaattatgat gtaggagaat ctttatagat
    17761 aaaaagaggt ggaaaggcac tattaaagac tttaagtcta aaaaggtatc aaagtatgcc
    17821 agagataaaa aaatataaat atgacacttt aaaggcgatt agaaaattaa agaaatgcta
    17881 gaagactttt agatgacagt taccaagagg gtctaatttt cactgctatt tatgcagtgg
    17941 gaattggacc tttttatata agcaaattct atttcaaaat tggttaccaa gaaagacttc
    18001 ttttcactgt taagtataag agggtaattt atagaatttt gttacatcaa gataaatatt
    18061 ttctgatggt caaattttaa aaagattaat aactctcgat aaattttgaa ccttaacaat
    18121 tgaatagacc aagacaagac gttaattatt tttggagcgt aataacctat ccgtcaagat
    18181 ctttcggctg aataattcgg caaaaaaagt tctgctaagc aaaaagaaag tgagcgataa
    18241 gtaagagttt gaatataggg agggataccc tatccgctat gaagaaaatg agggtaatga
    18301 tacttctaag gttgaagccg gctcatccgg aatagaggcg gaagtgagat tcctatgttg
    18361 ctaatccaaa gcacttgtca atgtcaaaaa acttaattaa acaaataatt attagatata
    18421 aaactttaga ggaggtatat attggacaat gactggaatg gattggctga tttaatagca
    18481 aatctgattg caaaatatgc tggtgcttta gatttagata atctacccga tccaacgcca
    18541 gcaaaaaatc aagagatgaa aaatagtttt gacatggcaa aaacacaaat tgagacggac
    18601 taataaaagt gttataatat acttgaaatg atagtccaaa cttaaattaa aaaaattata
    18661 tatgatatag aaaaattata ttgaggttaa tactatgtca aaagaaaaaa taaaagtata
    18721 cctctataca cgagtatcta cgtcaataca gatagagggg tattcgttag aggcacaaaa
    18781 atcacgaatg aaagcttttg ctatttacaa cgattatgaa attgttggag agtatgaaga
    18841 tgccgggaag tctgacaagt ctattgaagg tagaatacag ttcaatcgaa tgatggaaga
    18901 tataaaatct ggaaaagatg gagtatcttt tgttcttgtg tttaagttat caagatttgc
    18961 aagaaatgcc gctgatgttc tttctacact tcatataatg caggattatg gagttaatct
    19021 tatctgcgtt gaagatggca ttgattcatc taaagatgct gggaaactaa tgatttctgt
    19081 tttatcagct gtggctgaaa tagaaagaga aaacatcagt attcaaacaa tggaaggtcg
    19141 cattcaaaaa gcaggggaag gaaaatggaa tggtggcttt gctccgtatg gatataaact
    19201 tgaagacggc aagctgttta taaatgagga agaggcagtt gcaataagaa cgattttcga
    19261 ccagtatgta aatactacga taggagccaa tgggatatct aaatacttag agaatcatgg
    19321 aattagaaaa atcccaagac agaatggtaa gaatcctttg tttgatgcag gtcttataag
    19381 aaagatatta aagaatcctg tatataatgg gaaaatagca tttggaagaa gaactttaga
    19441 aaaagttcat ggtacaagaa atgaatataa gcaggttgaa caagatgaat atctaatatc
    19501 tgaagggata catgaagcta tagtttccga tgaagtttgg caagctgctc aggttaagct
    19561 aaaatctcaa gcaaagaaat atgagcatgt gaataaagga aaagatacac gcacacactt
    19621 gctttctgga attgtaaaat gcccgatatg tggagtggga atgtttggga acaagtgtat
    19681 caagaaaaag aaagatggca caaagtataa agatttttat tactatggtt gtaaccatag
    19741 gcagatgata agaggtaata agtgtacatt cagtaagcaa attagagaag aattgttaga
    19801 tgatgctgtt gcagaggtga ttgtcaagat agtaagtaat ccgaaatttg cttctatgat
    19861 gcaagaaaaa atcaacatga aggtggatac ctctgaaata gaaaaagaaa tagataatta
    19921 ccaaaaggaa ttgagaaaga gtcattctac aaagtttaag ctaattgagg aaatagataa
    19981 tttagatgtt gaagataagc attataagag aaggaaacag gatttagatg atagactata
    20041 tcgtatgtat gacaaactag atgaattaga atcatcacta attgatgcga aagcaaagaa
    20101 acagactatt gaagctgaaa agcttacagg agataacata tataaggttc tgatctattt
    20161 tgataagctc tataaagtca tgaatgatgt agagcgtagg cagttaattt cagctttgat
    20221 ttctgaaatt caagtttatg aagaaaaaca atctaacgga caatggctaa aatccattac
    20281 ttttaagcta ccaattatag aagaaaatct caacataggt ttggacaatg atgaacaagt
    20341 tgaatgtgta agtttattag agaaacgtag ttaatcctca aaaggttccc cgaacctttt
    20401 gagtcccact gacgcatcac gctgaggcgg tatcactgct tgtacgagtt gaagcatcag
    20461 caaagtaaaa gtagatgttc agccaatgcg acgaggtgag accgaaggtc gataaggtgt
    20521 gttctgggta taagactcgt aaagtaagta ggaaatatga tgagatgata cagagagcct
    20581 gaattggtca ggtgacgtgc ttatttacat tagcctgata atgaaaatgg agagattatc
    20641 gatggttata ttggaattgt accaaaatga ttattctaaa gatttagtag catttgattc
    20701 catagaagat gggaaagcct ttgtagctca aatcccggga tacactctgg aaacagaaga
    20761 tggttttgaa gtggagtatt ttaatcctaa aaacataccg gattatatgg aaattatttt
    20821 taacggaaat attgttcctt tatctaaatt tatgttcgat cctgaggaaa atgtaaacat
    20881 tatttggaaa gagatttcaa atttatccct caaaaatgat agagtgatcg aaggatattc
    20941 aaaaattgat gcatatgtcg ttaacaacca tgaagttaaa gcctatgtcg aaacaagaga
    21001 aacgaactat cgtaaagcaa aagacttctt agaaagccgc ggatatgaaa tcgacagaag
    21061 ctttttcgga agtgaagacg gtgaagcgat tctttacaga aaaaaaggga tcgaagtttg
    21121 gcatttcttg tgtcacttag acccaatgtt tgtagagatt gaagatgtag aaggatatgt
    21181 taaagaagaa gttggagaga ttcaatagtc aaccaaagtt ccttgtgagt atataccttt
    21241 gctagtaaaa gagtcaaaac gttataacga agggggggaa gaaaaccctt gagtgtaagt
    21301 ctttttcttg tttagaggga aagtattaga gtagccgctc ataatttata ctagatttga
    21361 taactgattt gagacagatt ttatttctat aaatattgtg aaaatttttt aataccaaag
    21421 atttaaagtt actgtgttaa aaatcctctc cacttttaaa ctaatgtatt ataaaagcca
    21481 gttgacacta gtgttacacc tgtgatagaa ttaacttgag gtgatgaaaa tggcaaccga
    21541 taaaaataga ataatgatta gcttggatga taaaaatcta gagaaacttg aaaatttagt
    21601 agaagatgct agagatagaa ggggaatgcg actaacaaag tcccaggtta ttgaattact
    21661 cctaaatacc gttgattatt tcgatgatat tatgggggct atttactcaa aaaaataaga
    21721 gcaaaattgc tattattttt tacaaattgg tgtaacacta gtgatatagg agtgatgaaa
    21781 tggttgttta tattagacaa agtaaattac caagtgaggt ttcaattaat aaatacaatg
    21841 ctcaagtagg tgcctactta caaggagaag aagttatttt atatcaatct ttttctgaaa
    21901 taaaagagtt aacaagtgaa gatatagttg tagattatat aatggagact agagcattac
    21961 taaaaatgat gggcttaaac gttccggttc atgactatcc tattgagctt aaagagtttt
    22021 atggtcgaaa gatttatgct ggtattttag gagagattgt gaatatacct gataattggg
    22081 gaaaatttat taagcctaaa gctggttcaa aagtctttac tggaagagtt gttaatggaa
    22141 cccatgattt aataggtatt ggtctacctt tcgactatcc tatatggatt agtgaggttg
    22201 tagaattcat agctgaatgg cgttgttttg tgttagatgg tcgcgtatta gatgttcgac
    22261 cctatacagg tgattatcat gcacaatttg atgcaagtgt aattgatgaa gcgatatcat
    22321 gttggaaaga tgcgccaata gcttatggac tagatatcgg tgttactcgc gatggcagaa
    22381 cacttgttgt tgaagtaaat gatggttatg cattgggaaa ttatggccta tctcctttaa
    22441 aatcaatcaa ttttcataga gctaggtgga aagaaatggt aaaaccctat tttgaaaaaa
    22501 atgaaatttt taaaatccaa caggatgtta ttttctaaaa taaatatggt agataaccaa
    22561 tataaaaagc atcaaaatga acaaggagga atctgatgct tggagcaatt attggagata
    22621 ttgtcggttc tgtttacgaa tggaacaata tcaaaacaaa ggactttcct ttatttcgga
    22681 aggactgctt ttttacagat gacacggtta tgacctgtgc tgttgcagaa gcaattatga
    22741 atggtggaca aaaagatgac ttcattgacg cgatgaagaa atatggcaga atgtatccga
    22801 atgctgatta cggtgctcgg tttaatgcat ggctaaacag cgataaccgt gagccttata
    22861 atagctttgg gaatggatca gctatgcgta tttctccatg tgcttggatc atggactgtg
    22921 gtttttatgc gaaaactggt atatggccat catctagagg acttacgagt ctttctgcag
    22981 aggtaactca taatcatcca gaaggtgtca aaggcgctat ggctacagct gatgctatct
    23041 ttctatgtcg tttttacttt ggtggttatt gtagagagta cgagcaatca attaacgaca
    23101 atcctacaga gtgtaaaaga cgaattaagg attatataga aaaagaatac gattacaatc
    23161 tatctcaaac tttagatgaa atccgtccta actatcgttt taacgaaaca tgtcaggaaa
    23221 ctgtccctca agccattatc gcctttcttg aaagtagaga cttcgaagat gcgataagaa
    23281 atgccatctc acttggtggc gacagtgata ctctcgcagc aatcacttgt agcatagcag
    23341 aggcagctta cggtattcct gattggatca aggataaggc ctattcttac ttggatgaac
    23401 ccttaaagga tgtagttagg cgatgggaaa atagaataaa agcgtattaa tctccagtac
    23461 gtcagatttc tcttttctgt attttcattg tataatagga ttacatttac ttgcatacga
    23521 cgaaatgtaa acatttctgt ttaaaattaa ggataaaatc aatgaaaaaa gcaatggtaa
    23581 ttatcaaccc tacttctggt ggcgagaagg ctttggatta caaagaaaag ctggagaata
    23641 aagcaaaaga atactttgaa tatgttgaaa ccaaaattac cgaaaaagcg ctggatgcaa
    23701 cacattttgc tgaagaagct tctcgtgagc agtatgatgc agtggttgtg tttggtggag
    23761 atggaactgt caatgaagtc atttcaggta ttgatgagag agactacatt cctaagttag
    23821 ggattatccc aggcggtacg ggtaacctca ttacaaaact tttggaaatc aatcaagaca
    23881 tcgatggcgc aattgacgaa ctggattttg atttaaccaa taagattgat atcggtaaag
    23941 caaatgacaa ctattttggt tatatcttta gtatcggttc tctgcctgag gcgattcaca
    24001 atgttgaaat agaggacaaa acaaaattcg gtattttaac ctatgctgta aataccatga
    24061 agtctgtcat gacagatcag gtctttaaca ttaaggttga gacagaaaat ggaaattatg
    24121 ttggtgaagc tagccatgtt ttggtccttt tgacaaatta cttcgctgat aagaaaatct
    24181 ttgaagaaaa caaggacggc tatgccaaca ttttgattct gaaagatgcc tctatattct
    24241 ccaaattatc cgtcattcct gatttattaa aaggggatgt tgtcgcaaat gataatatcg
    24301 agtatatcaa agcgcgtaat attaaaatct cttcagatag tgaattggag tcagatgttg
    24361 acggagataa atcagataac ctacctgtag aaatcaaagt cctagctcag cgagtagaag
    24421 tattttcaaa accgaaagag gattagtata tagagaaagc cttttttaag gctttttgta
    24481 tactttaaaa gatagttcct ttaacaacgg acattccttg caaatagttt acaaaaatag
    24541 tatactggat tcattgagtt tgaaaacgtt tgcgtaaaat ttgaatgaat actttaggag
    24601 acaaattgat ggaattgagt gctatttacc ataggcctga gtcggagtat gactatcttt
    24661 ataaggataa gaaactccat attcgaattc gaactaagaa aggggacatt gaaagcatca
    24721 acttgcacta tggggaccct tttatcttta tggaggagtt ttatcaggat acaaaagaaa
    24781 tggtcaagat aacttctggt accttatttg accattggca ggttgaagtg tcagttgact
    24841 ttgcacgtat ccagtatctc tttgagctca gagatacaga aggtcaaaat attttgtatg
    24901 gcgataaagg gtgtgtggaa aattctctag aaaatcttca tgcaattggg aatggattta
    24961 agttgcctta gcttcatgag attgatgcct gcaaggttcc tgactgggtt tcaaatacgg
    25021 tatggtatca gatatttcct gaaagatttg ccaatggcaa tgctctatta aacccagaag
    25081 ggactttaga ctgggattca tctgtcacac ctaagagcga tgatttcttt ggtggtgatt
    25141 tacaggggat tattgatcat atgaattact tgcaagactt gggtattact ggactatatc
    25201 tttgtcccat ctttgaatct acaagcaatc acaagtacaa tacgacagat tactttgaaa
    25261 ttgaccgtca ttttggagac aaggagacct ttcgggaact ggtggatcaa gcgcatcatc
    25321 gtggcatgaa agtcatgctg gatgcggtat ttaatcatat tggttcgcaa tctcttcaat
    25381 ggaaaaatgt cgtcaaaaat ggtgaacagt ctgcttataa ggattggttc catattcaac
    25441 aattcccagt gacaactgaa aagctagtta ataagagaga cttaccctat catgtttttg
    25501 gtttcgagga ctatatgcct aagctaaata cagccaatcc agaggtcaag aattatcttt
    25561 taaaggttgc gacttattgg attgaagagt ttaatatcga tgcttggcgt ttggatgtgg
    25621 ctaatgagat tgaccatcag ttctggaagg attttcgtaa ggcagtttta gctaaaaatc
    25681 ctgatcttta tatcctagga gaagtctggc atacatctca gccttggcta aatggagatg
    25741 agttccatgc cgtcatgaat tatcctttat ctgatagtat caaggactat ttcttacgag
    25801 gaattaagaa gacagaccag ttcatcgatg aaatcaatgg agagtctatg tattacaagc
    25861 agcagatttc agaggtcatg tttaatctct tggattcaca tgatacagag cgaatcctgt
    25921 ggacggccaa tgaagatgtt caactggtta aatcagcctt agcctttctc tttttacaaa
    25981 aaggaacacc gtgcatttat tacggaaccg agctagcctt gactggagga ccagatccag
    26041 attgtcgtcg ttgtatgcct tgggaacgtg tatcaagtga caatgatatg ctgaacttta
    26101 tgaagaggct gattaaaatt cggaaatacg cgtcagtaat catttcgcat ggcaagtata
    26161 gccttcaaga aatcaactct gatctagtag ctctggaatg gaaatacgaa ggacggatcc
    26221 tcaaagcaat attcaaccaa tcaacagaag attatctttt agagaaagaa gcagtagcac
    26281 tagcaagcaa ttgccaagaa ttggataatc agcttgtcat ctctccagat ggatttatga
    26341 ttttctaaaa actagttgat gaagattatg gtacatttca taccttatat agtataataa
    26401 ggctagttac taaacttgta aaggagaact taaatgaatt gtagaggaca tgaaacaaga
    26461 caaagaattg ttagagattt tgaagttcag cctaaagcac atattaagct gttagcaaat
    26521 caacaaaaac atagtgatgc aggagcaact attgaagatg aatattatgt atttatcgct
    26581 gagagtaaaa ttgatggcaa gaaggaagtt attcagtgtt gcatgggtgc ggcaagggat
    26641 tttttagaac taattaatca caaagggcta cctcttttta atccgcttgt aggtgattct
    26701 catgtaaata atagacaaga atatgacaat acagggagtg gaaatttata acctgaaaag
    26761 tggaatgaaa ctgcaaagca gctttataat gctataatgt ggttgattat tttatggaat
    26821 gctaagccgg atacaccttt atttaatttt aaagacgaag taattaagta taaaacatat
    26881 gagccttttg aaagcagtat aaaaagagta aatactacta taaagaatgg tagtaaaggg
    26941 aaaactctga ctgagatgat taatggctac agagcggata acgatattag agatgaaatt
    27001 tgtaacttta atattctgaa aaataaaatt cgtgatatga aaaaccaaca aggaaataca
    27061 atggaatctt acttttagtt attgttgaat tttgggtatt ctataaaata tcctaattga
    27121 gatttaaata gtagactata caatatagtt aaaatatcag taaaaacaac actttattga
    27181 ggtattggat acgctttgct aatagcctaa taatcacatg tggagtgttg ctacaacgaa
    27241 aaaggtgata atccttgatt tcaagctatt ttataagcat tttgtctttg tagataaagg
    27301 caattttgac aataaaaatc ctaaaaggtg aatcgttata gatgtatttg tagatatcgt
    27361 ttgcgcatcg aaaaaattaa tacaagaata aatatttata gctctttagg tgacttttat
    27421 agaagtaaag tttaggatag aaaaacaaga aataacgcac catttttggt gcgttatgct
    27481 tttttatgct ataatggatt tataaaaata aaggagtttg ctatgattgg aaagaacata
    27541 aaatccttgc gtaaaacaca tgacttaaca caactcgaat ttgcacggat tgtaggtatt
    27601 tcacgaaata gtctgagtcg ttatgaaaat ggaacgagtt cagtctctac cgaattaata
    27661 gacatcattt gtcagaagtt taatgtatct tatgtcgata ttgtaggaga agataaaatg
    27721 ctcaatcctg ttgaagatta tgaattgact ttaaaaattg aaattgtgaa agaaagaggt
    27781 gctaatctat tatctcgact ctatcgttat caagatagtc agggaattag cattgatgat
    27841 gagtctaatc cttggatttt aatgagtgat gatctatctg atttgattca tacgaatatc
    27901 tatctagtag aaacttttga tgaaatagag agatatagtg gctatttgga tggaattgaa
    27961 cgtatgttag agatatctga aaaacggatg gtggcctaat ggaaatccaa gattatactg
    28021 atagtgaatt caaacatgct ttagcaagga atcttcgttc actgacaaga ggaaaaaagt
    28081 ccagtaagca acctatagcg attttgcttg gagggcaaag tggtgccggt aagactacaa
    28141 ttcatcgtat taaacagaaa gaatttcaag gaaatattgt tatcatagat ggtgatagtt
    28201 ttcgttctca gcatccacac tatttagaac tgcagcaaga atatggcaaa gacagtgtag
    28261 aatataccaa agattttgca ggaaaaatgg tagagtcttt agtaacaaaa ttgagtagtt
    28321 tgagatacaa tcttttgata gagggaactt tacgaacagt tgatgttcca aagaaaacag
    28381 cacaactctt gaaaaataag ggatatgaag tacaattggc cttaattgcg acaaagcctg
    28441 aattgtcgta tctaagtact cttatccgtt atgaagaact gtacattatc aatccaaatc
    28501 aagcacgcgc aactccaaaa gaacatcatg atttcattgt aaatcatcta gttgataaca
    28561 cacgaaaatt ggaagaacta gctatctttg aaagaattca aatttaccaa cgagatagaa
    28621 gttgtgtata tgattcaaaa gaaaatacaa cttcagcagc agatgttctt caagagttac
    28681 tctttgggga gtggagtcag gtagagaagg agatgttgca ggtgggggaa aagagactta
    28741 atgaattact tgaaaaataa acaattgata tttttaggag aatagaaatg agagggttta
    28801 ataacaagat aaagtctgtt tatcaagaac taacaaattc caaagagaaa ttcggtagct
    28861 ttcacaagac tttaattcat ttgcatacac ctgtttctta tgattacaag ctattttcta
    28921 attggactgc aacgaaatat agaaaaatta ctgaagatga actatatgat atattttttg
    28981 aaaataagaa aataaaagtt gataagacaa ttttttttag taattttgat aaggttgttt
    29041 tttctagttc aaaagaatat attagttttc ttatgttagc agaggcaatc ataaaaaatg
    29101 gaatagaaat agttgtagta actgatcata atactaccaa aggtattaaa aagttacaaa
    29161 tggcagtctc aatcataatg aaaaattatc cgatttatga tatacatcct catattttac
    29221 atggagtaga aattagtgca gcagataaat tgcatattgt atgtatatat gattatgaac
    29281 aagaatcatg ggttaatcaa tggttaagtg aaaatattat aagtgagaaa gatggaagtt
    29341 atcaacattc actgactata atgaaggatt tcaataatca aaaaatagtt aactatattg
    29401 ctcatttcaa tagttatgac attttgaaaa aaggttctca cttatcaggt gcatataaac
    29461 gaaaaatttt ttctaaagaa aatacacgat tttggagttt aatattaact cgaaagaatc
    29521 ttcgcaacaa cttgatattc tctataaaga agttggtgta ttaagtttgg gacaaaaagt
    29581 tgtagccatg cttgattttt tattagcata tagtgattat tctaaagact tcagaccatt
    29641 gattattgat cagcctgaag acaatctaga caatcgttat atttacaggc atttagttca
    29701 gcagtttaga gatgtgaaag ctcaacgtca aattatttta gcaacacata atgctacaat
    29761 tgtaacaaat tctatgacag atcaagttgt tattatggag tcagatggag ttaacggatg
    29821 gattgaatca cagggatatg ttagtgaaaa atatataaaa aatcatatca tcaatcaatt
    29881 agagggagga aaagattcct tcaagcataa aatgtctata tatgagacgg ctttatcaga
    29941 gtagagtcag aaaaagtagg ttagaaattt agcctacttt tttctttgtc cgacaggcat
    30001 agtgtacatc tgaggtccaa gtcctctgtg gatatttgct gcagatgaaa ccaatagcga
    30061 ctcctaagcc tgaatatcgt gaggtagggg ggataggaag gaattagcga aatcaaggtt
    30121 ctacaaacag aatcgtgact tgaagccata tatagcggat gaggaactct aaaatccaaa
    30181 taggtgtcgt aacctatata cgtaaattac gagagtaaac taggaaagat gtacggctta
    30241 ttccgtgagc gtttaggacg tagtacaacg aatcatggga gtcagctgaa cacatagtat
    30301 tgaagaaatt tctgtaatgg aaatggagcg aagaagtgaa caattaaatg aatacctctc
    30361 taattaaatt tgtcaattct aattcctggt atgaaaagac agtgacctga aaatgtaaac
    30421 gatgggagct gatcataaat ataggacggt acatgcagtg gtgttagaga ttagtcctta
    30481 cttgatttgt gataacttcc ccaaatttct tctgctatac ttttctcaac ttttaaaaat
    30541 ccaactaaga attttacctg ggggtttggg ggcggagcca ctaagttatc ttatcgttag
    30601 ctgtcaaaac tggtaggttt tgataggctg gcgatatgat ttttgggata ttgtggacac
    30661 aatatctgag ctcgcaaagc cttacaagaa tgaaaatcag ttgttggaaa agtgtactga
    30721 cattgtatgg tagctcacat tgtcagtaca agtattttgg aaaggaagta gcagtatgaa
    30781 acgagatgtg cgtgatattc ggaaacaatt tcgtttaaca gaagcagaag aaaagcaaat
    30841 tctagctttg atgagagagc ggggagagac taatttctct gattttcttc gtaaaagttt
    30901 actttcctct gatttacaaa aacagatgga gacatggttt gccctctggc aatcccaaaa
    30961 actagaacaa atcagtcgtg acgttcatga agttttaatc ttggcacagt cagaacgtca
    31021 agtcacccaa gagcatgtat ctattctctt aacgtgcgtg caggaattga ttcaagaggt
    31081 tgcaaacacc atacccctca gtaaagaatt tcgtgagaag tacatgaggt aagcacatgg
    31141 aacatcgtta ccgaaccaat ctcaagaaag tgtttttgtc tgatagtgag ttgaaccaac
    31201 taaatataaa tatcgatcaa agtggttgta aatccttttc tgaatatgcg agacgaactc
    31261 tactcgatcc tggtatgaat tttatcacga ttgacacaaa cggttaccaa gatttagtgt
    31321 ttgagttaaa gaggattggc aataatatca accagattgc tcgaagtgtt aatcaatctc
    31381 agttaatttc tggtgaagaa ttgcaggagt tgaaaaaagg aattggtgaa ttgataaaag
    31441 aagttgataa ggaatttaat ctgcaagcgc agaagctaaa ggagttccat ggtcatcact
    31501 aaacactttg ccattcacgg aaagagttac cgcagaaagc ttatcaagta cattctcaat
    31561 cctgagaaaa ccaataatct tgccttggtg tcggactatg gcatgaagaa ttttctggac
    31621 tttcctagct atgaggaaat ggtgcagatg tatcatgaaa atttcatcag caacgatacg
    31681 ctttacgatt ttcgccacga caggatggaa gaaaatcaac gaaaaataca cgctcaccac
    31741 atcattcagt ctttctcgcc agaggatcat ctcactcctg aacaaatcaa tcggataggt
    31801 tatgagactg tgaaggaatt aactggtggc aaatttcgtt ttatcgttgc gacccatgtt
    31861 gataaagacc acctgcacaa tcacatcatt atcaattcag tagatagcaa ttctgacaaa
    31921 aagctcaagt gggactacaa ggtggagcga aatcttcgca tgatttctga ccgtttttct
    31981 aaaatcgcag gtgctaaaat cattgagaac cgctattctc accagcggta tgaagtctat
    32041 cgtaagacta atcacaagta tgaactcaag cagcgactct attttttgat ggaacattct
    32101 agggactttg aggatttcaa aaagaatgct ccgctactac atgtggagat ggatttccgt
    32161 cacaagcatg ccaccttttt tattacggac tcaactatga aacaggtggt gcgtggcaag
    32221 caactcaatc gcaagcagcc ttacacagaa gaatttttta agaactactt tgccaaaaga
    32281 gaaatagaaa gtctcatgga atttttattg ctgaaagttg agaatatgga tgatttactt
    32341 cagaaagcaa aactttttgg actaactatc aatcctaaac aaaagcatgt ttcttttcaa
    32401 tttgcaggag tggaggtaaa ggagacagag ctagaccaga aaaatcttta tgatgtagag
    32461 tttttccaag attattttaa aaatagaaaa gattggcaag ctccagaaac tgaggatttc
    32521 gttcaacttt atcaagaaga aaagttatcc aaagaaaaag aacttccaag cgatgagaag
    32581 ttctgggagt cctatcaaga gttcaagagt aacagagatg ccgttcatga atttgaggtg
    32641 gagttgtcac tcaatcaaat tgaaaaagta gtggatgatg gaatttacgt caaggtcaag
    32701 tttggtattc gtcaggaggg acttatcttt gtgccgaaca tgcagcttga tatggaagag
    32761 gataaggtga aggttttcat cagggaaacc agctcctact atgtctacca caaagacgct
    32821 gccgagaaaa attgttatat gaaaggtcga accttaatta gacagttcag ctatgaaaat
    32881 caaaccattc cattacgcag aaaagcgaca gtcgatatga ttaaagagaa gattgcggaa
    32941 gtggatgctt tgattgaact ggaagtagaa aatcaatctt atgtcacgat taaagatgag
    33001 ttagtgcatg aactagcagc gtctgaattg agaatcaatg agttgcaaga acgaatgtca
    33061 accttgaatc aagtagcaga atatctactg gcttcagttg aaagtaagca agaaatgaaa
    33121 ttaaatcttt caaaactgaa tataactgag aatatcagtg ctaatattgt tgagaaaaaa
    33181 ttgaagagcc tggggaatca actggaattg gaaaggggca ggtatgaaaa gatggtagtc
    33241 aggctagata aatttataaa tcgcttaaat acaggacttt caaaaggaga tgggatagat
    33301 tttcaaaaat aggaatctag ccaataatta tatacaatgt gtatcttttg taaaatatat
    33361 ttgaaattta gatttaatca tgttacaatt aacattgaaa tcaaatagaa aaggaagatg
    33421 caaacgtggg tacactatta gcaacaagat taaaaaatag acgaaaagaa ttaaaaatgt
    33481 ctcagcgaga attagctgag ggtatctgta aacaggggca aattagtcga ttagagagtg
    33541 gagagttcac ccctggagcg gattttttac atgcccttgc taagaaatta aaagttagta
    33601 tggactactt ttttgatgag caggttgtag aggaagtcaa tgagttatca gagtttaaga
    33661 agttagcaca gacatttatc acaaatcgta attatgaatc tttaaaatat atatatgaat
    33721 tggaaaatgt aaaagcccat cgcttatctc tagcagataa attttacatg gaatggataa
    33781 agtctcttat agatttttat ttttatggac agaaagaaga ggcaattaca cgattagaga
    33841 atatgctacc tcagttaaat gtatctgatt tgaactacct tcaagtttca aacactctat
    33901 tcaattttta ttatgatatt gaagatttag aacgttttaa tgagattaga gacaagctag
    33961 agcatcaagt gaatcagctt aatttaaaca caattgaaga gttagaacta tcaattaagt
    34021 tcaattataa cgtttgtcga tacctatggt tacagaaaaa tattgaagaa gctattacga
    34081 aaatcacagc tacgataaag caatgtaagg agtacaggac aacttatcta ttagctgatt
    34141 tgtatttatt gatgggaagt gtaagtgaaa atttttcttc taaaagttca gtaaaagaat
    34201 attttgagac tgctcatttt ctctacaaac ttgaggaaaa catgtcaatg gctttgaaag
    34261 tcgaacatta ttttgcagat ataacagaat aaggaatacg gtgttctagt gagcatcgtt
    34321 ttttaaatct aatttgaata caaaaaagta ttaaataaaa aaaaataaaa aaagattata
    34381 aaaatacttg acaagctaat tttgaagtga taaaataaat gcaagaaaac gaaaggagag
    34441 gtatatgaga agtttgttta ggaaaattgt tgctttgtta gtcataggat taatcctatt
    34501 agggactgct ggaggaactc aagttcataa gatggctaga gggattgatc caggtcctgc
    34561 gaatggtatt tatagatagg agattatagt cacttaaaaa tcaaaaaatt ataaaatttt
    34621 tgttttactt aaatagatat tttatgatgg gcgaagtttt tataactagt tcctataagt
    34681 acagaaacct attttaattt actaatttca aaacaatttt ttgagatata tgtaattaaa
    34741 tctaaattaa gctttaaaaa attattttta gcaatttgat tttgaaagtg tcatgcagca
    34801 atatgaaagc gtagaataga ggtgtttcca atgtacaagt aagttttgat tccaaataaa
    34861 gtaatagaaa aggagctata taatgagtag tcaaatgaaa gctttcttga atgaacttca
    34921 aggaaatatg gaagttgttg gagaattttt tgataatcct gaaaaggtaa ttagaaaatt
    34981 tggaattgtc ggaagagaga aggaagcatt gctaatccgt gacttaaatg atatggatga
    35041 ttatgctctt tcaattcaaa atagcgttgc atcgccttct ggggcacata gtagcacttg
    35101 ccattttgtt agacaagatt tacaatccgc ataattgtta atatataaaa cataaaattt
    35161 caattttcaa ttagggataa tagaattcct tactatgata tagaaagtga attaattagg
    35221 aaatcttagt cagaggtttc tgattaattc attttttata tattaagagt gatgtgaaat
    35281 gttcaaattg tgagactact ctcggattgt tgtatagaaa tttaaaattt tattgtgagc
    35341 tttttaagga agagtggccg atatgaaaaa taaatacgat gttaaaagaa ttattccgga
    35401 tgaattatca gaatcactag atatttttct aaaaaattat tctgaaactg gattgtcaga
    35461 ttataatact tatctctttt atggttttat cttgaagtcc tataaattgc ctcgagaaaa
    35521 tagatatagc ataaaattat tggtgaagga attacaaaat agaggactga aagttacatt
    35581 gattatcaac atttattatc acgctttaaa ttgtttggct ttaaatgatg gtctaaaaat
    35641 ttatggagaa gatttcttaa tatgaattac gaaaagtatt taaactattt ggactatgaa
    35701 actgaaatag aagacgcata ccataattta ttattagaat ataaaattag tgataatttt
    35761 agtgatgaac attggttata taatttgccg tctaatatca cccaatctaa gggatttaaa
    35821 atacacctga gcgcttcaat attaaatgct aatttggttg ctaaaaaatt ctttgatttt
    35881 atattttcta gagagaagaa gataaatttc aaaattttgg ttagcattaa agaactttct
    35941 ttgcaaaata cagggcttaa tggttattca caagtcggga aattcattac aatttatcca
    36001 aaagataata aagagtttca acgtttgtta cacaaattag aaatattgta taaaggtgta
    36061 aagggtgtaa acataccatc agatttcaga tttcaactta gcgaggttgt atattacaga
    36121 tatggggagt tcgtaaaaga tagcactttc aaggataaaa gagataagaa aatcccttca
    36181 aatgtgaatg ttccaataag ggattactat attccaagat ataacactat tcctgatcaa
    36241 tatattattt tggaagtgat ttctaaaaat gccaaaggtg gagtttataa agtatttaat
    36301 actcaaaagc gagtttattc tttattaaaa gaagctagtg atttatcgtt ggttgatttt
    36361 acaaatagag attctgtgaa tcgtttaata aatgaaagag aaatattagt agaattggaa
    36421 aaggaggaat ttactccaaa agtttttaac gatttttaca taaagaattc gtattttgtg
    36481 gaatttgagt ttattattgc agataaatta agcgagtata atatggttag tggctcgtat
    36541 gattggtttt taacattaat tgattatatg gagataataa actccaaata taatctttcc
    36601 tatagagatt tatcatttaa taatatactt attgataata gaaataatat ttatattata
    36661 gactttgagc atgccctaag gaaagaaact caaattgaag aaaaaaagtt gcctctattt
    36721 ggaactccag ggttttatga aaccaactta aatttattga ataatcaacc agaggatatt
    36781 atgggattgg ttttgttatt atattggagt cagaatttag atgattttaa cgtcttttca
    36841 aaaatgagtt ttttagaagc gatggagtat gcaatgaatt ttaattcgcg tcgcttagac
    36901 acacttgata aatcagattg gctttatgat atttataaaa aagcgttcaa ttataaatat
    36961 gatacttttt ctgaattaaa aaaagatttt atagaggtat taaaataaag gtaggggtgt
    37021 tatgaattgt ttcttgaaaa tgaataatgt aagtgttcgt tatgatgacg taatagcttt
    37081 aaaagatata actttacaaa taaataaggg agatttcatt ggcttattag gttcaaatgg
    37141 tgcaggtaaa tctacgttaa ttaattctat tgtaggtttt caagagattt atttaggaga
    37201 aatagagtat tgtgataaag atttgatagt tagttctcaa ccttttgctc atttaggctt
    37261 tactcctcaa accacagtaa ttgattttta tactactgtg aaggacaatg taatattggg
    37321 gctgaacctt gctggaaagt ttgggaaaaa tgctgagaag ttgtgtcaaa tagccttaga
    37381 aattgttggg ttagctgata aaaaaaataa tttggtagaa acattgtcag gtggacaact
    37441 gcaacgcgtc cagattgcta gagcaatagc tcataatcca gatttttata ttttagatga
    37501 acctaccgtt ggtttagata ctgaatctgc cgaaaaattt ttaatgtatt taaaagataa
    37561 gagtttggaa ggaaaaacta ttatcatatc ttcacatgac ataaatctac tcgaaaagtt
    37621 ttgtaaaaaa atactttttt tacaaaatgg ctccatatca ttttttggtg atatgcgtga
    37681 ctttgtagat aattcaacta tcaaattaaa tttttcaatg cagaatagaa tttctagata
    37741 tcaaattgaa tttttagaaa attttagatt taaagttcac atcgaagata atgatagttt
    37801 tacaatagaa gtccctatag aagaaaagat cttagatgtt atcaatgagg taggaaaagc
    37861 atgtgaaatt aaaaactttt caacaagtaa attaacctta caagaaagtt atttgcaaag
    37921 aataggagga gaaaaatgaa ggctgatcaa ttaaggcaca aatcggactt aggtttaaga
    37981 ggtctagcga ttattgctaa aaatgagatt attgcttttt ttagaagtaa aggtttaatt
    38041 atttctcagt ttctacaacc aatcttatat gttgttttta taataatagg attaaattct
    38101 tcgataaaga acattcagtt taatgatata aaaacctctt atgcagaata tacaatcatt
    38161 ggtgttatag ctttattgat aatcgggcag atgactcaag ttatttatag ggtgacaata
    38221 gataaaaaat atgggctact tgctcttaag ttatgcagtg gagttcgtcc tttatattat
    38281 attttaggga tgagtatcta ttctatatta gggttgatag ttcaagaaat tattatatat
    38341 ataattacgt tagcgtttga gataaatatc gcaatggata gattttttta tacagttttg
    38401 ttatctattg ttgttttatt attttgggac tcccttgcaa ttttacttac aatgtttatc
    38461 aatgattaca gaagacgtga tattgtaata cgttttgtac taacaccgct tggttttaca
    38521 gctcctgttt tctacttaat agattctgct cctagtattg tgagatggat tggtcagtta
    38581 aatcccttaa cttatcaatt aactattttg agaaactttt attttaaaaa ttcaacaact
    38641 ttggaattag ttttcttatt gttaacatca ttacttgtcc ttatatctgt atcttttatt
    38701 ataccaaaga taaaattgat actgatagaa agataaaagt tgggtcatcc aacttt
//
LOCUS       DAVFER010000020        34117 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1105170250
            SAMEA2167659-rid19724873.denovo.020, whole genome shotgun sequence.
ACCESSION   DAVFER010000020 DAVFER010000000
VERSION     DAVFER010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2167659
            Sequence Read Archive: ERR388902
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 34117)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34117)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928716.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928716.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 04:07:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,118
            CDSs (total)                      :: 2,073
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 120
            CDSs (without protein)            :: 120
            Pseudo Genes (ambiguous residues) :: 0 of 120
            Pseudo Genes (frameshifted)       :: 67 of 120
            Pseudo Genes (incomplete)         :: 47 of 120
            Pseudo Genes (internal stop)      :: 34 of 120
            Pseudo Genes (multiple problems)  :: 23 of 120
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34117
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2167659-rid19724873.denovo.020"
                     /strain="1105170250"
                     /db_xref="taxon:1313"
     gene            123..344
                     /locus_tag="VU534_001048"
     CDS             123..344
                     /locus_tag="VU534_001048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU1513651.1"
                     /translation="MYRRLRDLREDHDLPQKQIATILSFTNSAYAKIERGEHALTADV
                     LVKLSDFYDVSTDYLLGLTDFPDKIRFRK"
     gene            791..1093
                     /locus_tag="VU534_001049"
                     /pseudo
     CDS             791..1093
                     /locus_tag="VU534_001049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            1249..2478
                     /locus_tag="VU534_001050"
     CDS             1249..2478
                     /locus_tag="VU534_001050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HEU1513652.1"
                     /translation="MKISKRHLLNYSILIPYLLLSILGLIVVYSTTSAILIEEGKSAL
                     QLVRNQGIFWIVSLILIALIYKLRLDFLRNERLIILVILIEMLLLFLARFIGISVNGA
                     YGWISVAGITIQPAEYLKIIIIWYLAHRFSKQQEEIATYDFQVLTQNQWLPRAFNDWR
                     FVLLVLIGSLGIFPDLGNATILVLVSLIMYTVSGIAYRWFSTILALVSAASVFVLTTI
                     SLIGVETFSKIPVFGYVAKRFSAFFNPFADRADAGHQLANSYFAMVNGGWFGLGLGNS
                     IEKRGYLPEAHTDFVFSIVIEEFGFVGASLILALLFFMILRIILVGIRAENPFNAMVA
                     LGVGGMMLVQVFVNIGGISGLIPSTGVTFPFLSQGGNSLLVLSVAVAFVLNIDASEKR
                     AKLYRELENQPMNLLLK"
     gene            2498..5194
                     /gene="ppc"
                     /locus_tag="VU534_001051"
     CDS             2498..5194
                     /gene="ppc"
                     /locus_tag="VU534_001051"
                     /EC_number="4.1.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxylase"
                     /protein_id="HEU1513653.1"
                     /translation="MSLQKLENYSNKSVVQEEVLILTELLEDITKNMLAPETFEKIIQ
                     LKELSTQEDYQGLNRLVTSLSNDEMVYISRYFSILPLLINISEDVDLAYEINHQNNID
                     QDYLGKLSTTIKLVAEKENAVEILEHLNVVPVLTAHPTQVQRKSMLDLTNHIHSLLRK
                     YRDVKLGLINKDKWYNDLRRYIEIIMQTDMIREKKLKVTNEITNAMEYYNSSFLKAVP
                     HLTTEYKRLAQAHGLNLKQAKPITMGMWIGGDRDGNPFVTAKTLKQSALTQCEVIMNY
                     YDKKIYQLYREFSLSTSIVNVSKQVREMARQSKDNSIYREKELYRRALFDIQSKIQAT
                     KTYLIEDEEVGTRYETANDFYKDLIAIRDSLLENKGESLISGDFVELLQAVEIFGFYL
                     ASIDMRQDSSVYEACVAELLKSAGIHSRYSELSEEEKCDLLLKELEEDPRILSATHAE
                     KSELLAKELAIFKTARVLKDKLGDDVIRQTIISHATSLSDMLELAILLKEVGLVDTER
                     ARVQIVPLFETIEDLDHSEETMRKYLSLSLAKKWIDSRNNYQEIMLGYSDSNKDGGYL
                     SSCWTLYKAQQQLTAIGDEFGVKVTFFHGRGGTVGRGGGPTYEAITSQPLKSIKDRIR
                     LTEQGEVIGNKYGNKDAAYYNLEMLVSAAINRMITQKKSDTNTPNRYETIMDQVVDRS
                     YDIYRDLVFGNEHFYDYFFESSPIKAISSFNIGSRPAARKTITEIGGLRAIPWVFSWS
                     QSRVMFPGWYGVGSSFKEFINKNPENIAILRDMYQNWPFFQSLLSNVDMVLSKSNMNI
                     AFEYAKLCEDEQVKAIYETILNEWQVTKNVILAIEGHDELLADNPYLKASLDYRMPYF
                     NILNYIQLELIKRQRRGELSSDQERLIHITINGIATGLRNSG"
     misc_binding    5277..5494
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            5607..6611
                     /locus_tag="VU534_001052"
     CDS             5607..6611
                     /locus_tag="VU534_001052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEU1513654.1"
                     /translation="MKNKRLIGIIAALAVLVAGSLIYSSMNKSEAQNNKDEKKITKIG
                     VLQFVSHPSLDLIYKGIQDGLAEEGYKDDQVKIDFMNSEGDQSKVATMSKQLVANGND
                     LVVGIATPAAQGLASATKDLPVIMAAITDPIGANLVKDLKKPGGNVTGVSDHNPAQQQ
                     VELIKALTPNVKTIGALYSSSEDNSKTQVEEFKAYAEKAGLTVETFAVPSTNEIASTV
                     TVMTSKVDAIWVPIDNTIASGFPTVVSSNQSSKKPIYPSATAMVEVGGLASVVIDQHD
                     LGVATGKMIVQVLKGAKPADTPVNVFSTGKSVINKKIAQELGITIPESVLKEAGQVIE
                     "
     gene            6680..7546
                     /locus_tag="VU534_001053"
     CDS             6680..7546
                     /locus_tag="VU534_001053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU1513655.1"
                     /translation="MIVSIISQGFVWAILGLGIFMTFRILNFPDMTTEGSFPLGGAVA
                     VTLITKGVNPFLATLVAVGAGCLAGMAAGLLYTKGKIPTLLSGILVMTSCHSIMLLIM
                     GRANLGLLGTKQIQDVLPFDSDLNQLLTGLIFVSIVIALMLFFLDTKLGQAYIATGDN
                     PDMARSFGIHTGRMELMGLVLSNGVIALAGALIAQQEGYADVSRGIGVIVVGLASLII
                     GEVIFKSLSLAERLVTIVVGSIAYQFLVWAVIALGFNTSYLRLYSALILAVCLMIPTF
                     KQTILKGAKLSK"
     gene            7543..8301
                     /locus_tag="VU534_001054"
     CDS             7543..8301
                     /locus_tag="VU534_001054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU1513656.1"
                     /translation="MTAIVELKNATKIVKNGFDEEKIILNDVSLEIFERDFITILGGN
                     GAGKSTLFNTIAGTLSLTSGTIRILGEDLTKFSPEKRAKYLSRVFQDPKMGTAPRMTV
                     AENLLIAKFRGEKRGLLPRRLTSYKDEFQATIEKVGNGLEKHLNTPIEFLSGGQRQAL
                     SLLMATLKRPELLLLDEHTAALDPKTSVALMELTDEFVKKDQLTALMITHHMEDALKY
                     GNRLIVMKEGRIIQDLNQEEKAKMKISDYYQLFE"
     gene            8391..10151
                     /gene="dnaG"
                     /locus_tag="VU534_001055"
     CDS             8391..10151
                     /gene="dnaG"
                     /locus_tag="VU534_001055"
                     /EC_number="2.7.7.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000227865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HEU1513657.1"
                     /translation="MVDKQVIEEIKNNANIVEVIGDVISLQKAGRNYLGLCPFHGEKT
                     PSFNVVEDKQFYHCFGCGRSGDVFKFIEEYQGVPFIEAVQILGQRVGIEVEKPLYSEQ
                     KSASPHQALYDMHEDAAKFYHAILMTTTMGEEARNYLYQRGLTDEVLKHFWIGLAPPE
                     RNYLYQRLSDQYREEDLLDSGLFYLSDANQFVDTFHNRIMFPLTNDQGKVIAFSGRIW
                     QKTDSQTSKYKNSRSTAIFNKSYELYHMDRAKRSSGKASEIYLMEGFMDVIAAYRAGI
                     ENAVASMGTALSREHVEHLKRLTKKLVLVYDGDKAGQAATLKALDEIGDMPVQIVSMP
                     DNLDPDEYLQKNGPEDLAYLLTKTRISPIEFYIHQYKPENSENLQAQIEFLEKIAPLI
                     VQEKSIAAQNSYIHILADSLASFDYTQIEQIVNESRQVQRQNRMEGISRPTPITMPVT
                     KQLSAIMRAEAHLLYRMMESPLVLNDYRLREDFAFATPEFQVLYDLLGQYGNLPPEVL
                     AEQTEEVERAWYQVLAQDLPAEISPQELSEVEMTRNKALLNQDNMRIKKKVQEASHVG
                     DTDTALEELERLISQKRRME"
     gene            10154..11263
                     /gene="rpoD"
                     /locus_tag="VU534_001056"
     CDS             10154..11263
                     /gene="rpoD"
                     /locus_tag="VU534_001056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HEU1513658.1"
                     /translation="MATKQKEVTTFDVQVAEFIRNHKQKGTATDDEINASLVIPFTLD
                     ADGIEDLLQRIQDAGISITDNEGNPSARVLSNEEEPELSDEDLIGSTSAKVNDPVRMY
                     LKEIGVVPLLTNEEEKELALAVEAGDIEAKQRLAEANLRLVVSIAKRYVGRGMQFLDL
                     IQEGNMGLMKAVDKFDYSKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETINK
                     LVREQRNLLQELGQDPTPEQIAERMDMTPDKVREILKIAQEPVSLETPIGEEDDSHLG
                     DFIEDEVIENPVDYTTRIVLREQLDEILDTLTDREENVLRLRFGLDDGKMRTLEDVGK
                     VFNVTRERIRQIEAKALRKLRQPSRSKPLRDFIED"
     gene            11277..11606
                     /locus_tag="VU534_001057"
     CDS             11277..11606
                     /locus_tag="VU534_001057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HEU1513659.1"
                     /translation="MAYTEEQIENIKTRILTALEEVIDPELGIDIVNLGLIYEIRFDG
                     DTGQTEIDMTLTTMGCPLADLLTDQIYDAMIEVPEVTDTEVKLVWYPAWTVEKMSRYA
                     RIALGIK"
     gene            11721..12764
                     /gene="cpoA"
                     /locus_tag="VU534_001058"
     CDS             11721..12764
                     /gene="cpoA"
                     /locus_tag="VU534_001058"
                     /EC_number="2.4.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosylglucosyldiacylglycerol synthase"
                     /protein_id="HEU1513660.1"
                     /translation="MEKKKLRINMLSSSEKVAGQGVSGAYRELVRLLHRAAKDQLIVT
                     ENLPIEADVTHFHTIDFPYYLSTFQKKRSGRKIGYVHFLPATLEGSLKIPFFLKGIVK
                     RYVFSFYNRMEHLVVVNPMFIEDLVAAGIPREKVTYIPNFVNKEKWHPLPQEEVVRLR
                     TDLGLSDNQFIVVGAGQVQKRKGIDDFIRLAEELPQITFIWAGGFSFGGMTDGYEHYK
                     KIMENPPKNLIFPGIVSPERMRELYALADLFLLPSYNELFPMTILEAASCEAPIMLRD
                     LDLYKVILEGNYRATAGREEMKEAILEYQANPAVLKDLKEKAKNISREYSEEHLLQIW
                     LDFYEKQAALGRK"
     gene            12780..14105
                     /locus_tag="VU534_001059"
     CDS             12780..14105
                     /locus_tag="VU534_001059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HEU1513661.1"
                     /translation="MRIGLFTDTYFPQVSGVATSIRTLKTELEKQGHAVFIFTTTDKD
                     VNRYEDWQIIRIPSVPFFAFKDRRFAYRGFSKALEIAKQYQLDIIHTQTEFSLGLLGI
                     WIARELKIPVIHTYHTQYEDYVHYIAKGMLIRPSMVKYLVRGFLHDVDGVICPSEIVR
                     DLLSDYKVKVEKRVIPTGIELAKFERPEIKQENLKELRSKLGIQDGEKTLLSLSRISY
                     EKNIQAVLAAFADVLKEEDKVKLVVAGDGPYLNDLKEQAQNLEIQDSVIFTGMIAPSE
                     TALYYKAADFFISASTSETQGLTYLESLASGTPVIAHGNPYLNNLISDKMFGTLYYGE
                     HDLAGAILEALIATPDMNEHTLSEKLYEISAENFGKRVHEFYLDAIISNNFQKDLAKD
                     DTVSQRIFKTVLYLQQQVVAVPVKGSRRMLKASKTQLISMRDYWKDHEE"
     gene            14136..14312
                     /locus_tag="VU534_001060"
     CDS             14136..14312
                     /locus_tag="VU534_001060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HEU1513662.1"
                     /translation="MRSGRDKKIAGVCAGVAHYLDMDPTIVQVIWGVLTCCYGAGIVA
                     YIILWIIAPVATDY"
     gene            14371..14505
                     /locus_tag="VU534_001061"
     CDS             14371..14505
                     /locus_tag="VU534_001061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4044 domain-containing protein"
                     /protein_id="HEU1513663.1"
                     /translation="MAFGDNGNRKKTMFEKITLFIVIIMLVASLLGIFATAIGALSNL
                     "
     gene            14569..15879
                     /gene="obgE"
                     /locus_tag="VU534_001062"
     CDS             14569..15879
                     /gene="obgE"
                     /locus_tag="VU534_001062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HEU1513664.1"
                     /translation="MSMFLDTAKIKVKAGNGGDGMVAFRREKYVPNGGPWGGDGGRGG
                     NVVFVVDEGLRTLMDFRYNRHFKADSGEKGMTKGMHGRGAEDLRVRVPQGTTVRDAET
                     GKVLTDLIEHGQEFIVAHGGRGGRGNIRFATPKNPAPEISENGEPGQERELQLELKIL
                     ADVGLVGFPSVGKSTLLSVITSAKPKIGAYHFTTIVPNLGMVRTQSGESFAVADLPGL
                     IEGASQGVGLGTQFLRHIERTRVILHIIDMSASEGRDPYEDYLAINKELESYNLRLME
                     RPQIIVANKMDMPESQENLEDFKKKLAENYDEFEELPAIFPISGLTKQGLATLLDATA
                     ELLDKTPEFLLYDESDMEEEAYYGFDEEEKAFEISRDDDATWVLSGEKLMKLFNMTNF
                     DRDESVMKFARQLRGMGVDEALRARGAKDGDLVRIGKFEFEFVD"
     gene            15889..16047
                     /locus_tag="VU534_001063"
     CDS             15889..16047
                     /locus_tag="VU534_001063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1513665.1"
                     /translation="MGDKPISFRDADGNFVSAADVWNEKKLEELFNRLNPNRALRLAR
                     TKKENPSQ"
     gene            17190..18449
                     /locus_tag="VU534_001064"
     CDS             17190..18449
                     /locus_tag="VU534_001064"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HEU1513666.1"
                     /translation="MRKIVINGGLPLQGEITISGAKNSVVALIPAIILADDVVTLDCV
                     PDISDVASLVEIMELMGATVKRYDDVLEIDPRGVQNIPMPYGKINSLRASYYFYGSLL
                     GRFGEATVGLPGGCDLGPRPIDLHLKAFEAMGATASYEGDNMKLSAKDTGLHGASIYM
                     DTVSVGATINTMIAAVKANGRTIIENAAREPEIIDVATLLNNMGAHIRGAGTNIIIID
                     GVERLHGTRHQVIPDRIEAGTYISLAAAVGKGIRINNVLYEHLEGFIAKLEEMGVRMT
                     VSEDSIFVEEQSNLKAINIKTAPYPGFATDLQQPLTPLLLRANGRGTIVDTIYEKRVN
                     HVFELAKMDADISTTNGHILYTGGRDLRGASVKATDLRAGAALVIAGLMAEGKTEITN
                     IEFILRGYSDIIEKLRNLGADIRLVED"
     gene            18465..19016
                     /locus_tag="VU534_001065"
     CDS             18465..19016
                     /locus_tag="VU534_001065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU1513667.1"
                     /translation="MNIWTKLAMFSFFETDRLYLRPFFFSDSQDFREIASNPENLQFI
                     FPTQASLEESQYALANYFMKSPLGVWAICDQKNQQMIGSIKFEKLDEIKKEAELGYFL
                     RKDAWSQGFMTEVVRKICQLSFEEFGLKQLFIITHLENKASQRVALKSGFSLFRQFKG
                     SDRYTRKMRDYLEFRYVKGEFNE"
     gene            19009..20286
                     /locus_tag="VU534_001066"
     CDS             19009..20286
                     /locus_tag="VU534_001066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEU1513668.1"
                     /translation="MSKHQEILSYLEELPVGKRVSVRSISNHLGVSDGTAYRAIKEAE
                     NRGIVETRPRSGTIRVKSQKVAIERLTFAEIAEVTSSEVLAGQEGLEREFSKFSIGAM
                     TEQNILSYLHDGGLLIVGDRTRIQLLALENENAVLVTGGFQVHDDVLKLANQKGIPVL
                     RSKHDTFTVATMINKALSNVQIKTDILTVEKLYRPSHEYGFLRETDTVKDYLDLVRKN
                     RSSRFPVINQHQVVVGVVTMRDAGDKSPSTTIDKVMSRSLFLVGLSTNIANVSQRMIA
                     EDFEMVPVVRSNQTLLGVVTRRDVMEKMSRSQVSALPTFSEQIGQKLSYHHDEVVITV
                     EPFMLEKNGVLANGVLAEILTHMTQDLVVNSGRNLIIEQMLIYFLQAVQIDDILRIQA
                     RIIHHTRRSAIIDYDIYHGHQIVSKANVTVKIN"
     gene            20302..21162
                     /locus_tag="VU534_001067"
     CDS             20302..21162
                     /locus_tag="VU534_001067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl aminopeptidase"
                     /protein_id="HEU1513669.1"
                     /translation="MITLKSAREIEAMDKAGDFLASIHIGLRDLIKPGVDMWEVEEYV
                     RRRCKEENFLPLQIGVDGAMMDYPYATCCSLNDEVAHAFPRHYILKDGDLLKVDMVLG
                     GPIAKSDLNVSKLNFNNVEQMKKYTQSYSGGLADSCWAYAVGTPSEEVKNLMDVTKEA
                     MYKGIEQAVVGNRIGDIGAAIQEYAESRGYGVVRDLVGHGVGPTMHEEPMVPNYGIAG
                     RGLRLREGMVLTIEPMINTGDWEIDTDMKTGWAHKTIDGGLSCQYEHQFVITKDGPVI
                     LTSQGEEGTY"
     gene            21542..22345
                     /locus_tag="VU534_001068"
                     /pseudo
     CDS             21542..22345
                     /locus_tag="VU534_001068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
     gene            22536..24827
                     /gene="pcrA"
                     /locus_tag="VU534_001069"
     CDS             22536..24827
                     /gene="pcrA"
                     /locus_tag="VU534_001069"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000992850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PcrA"
                     /protein_id="HEU1513670.1"
                     /translation="MNALLNGMNDRQAEAVQTTEGPLLIMAGAGSGKTRVLTHRIAYL
                     IDEKLVNPWNILAITFTNKAAREMKERAYSLNPATQDCLIATFHSMCVRILRRDADHI
                     GYNRNFTIVDPGEQRTLMKRILKQLNLDPKKWNERTILGTISNAKNDLIDDVAYAAQA
                     GDMYTQIVAQCYTAYQKELRQSESVDFDDLIMLTLRLFDQNPDVLTYYQQKFQYIHVD
                     EYQDTNHAQYQLVKLLASRFKNICVVGDADQSIYGWRGADMQNILDFEKDYPKAKVVL
                     LEENYRSTKTILQAANEVIKNNKNRRPKNLWTQNADGEQIVYYRADDELDEAVFVART
                     IDELSRSQNFLHKDFAVLYRTNAQSRTIEEALLKSNIPYTMVGGTKFYSRKEIRDIIA
                     YLNLIANLSDNISFERIINEPKRGIGLGTVEKIRDFANLQNMSMLDASANIMLSGIKG
                     KAAQSIWDFANMMLDLREQLDHLSITELVESVLEKTGYVDILNSQATLESKARVENIE
                     EFLSVTKNFDDTTDVTEEETGLDKLSRFLNDLALIADTDSGSQETSEVTLMTLHAAKG
                     LEFPVVFLIGMEENVFPLSRATEDSDELEEERRLAYVGITRAEKILYLTNANSRLLFG
                     RTNYNRPTRFINEISSDLLEYQGLARPANTSFKASYSSGSISFGQGMSLAQALQDRKR
                     GAAPKSIQSSGLPFGQFTAGAKPASSEANWSIGDIALHKKWGEGTVLEVSGSGARQEL
                     KINFPEVGLKKLLASVAPIEKKI"
     gene            24870..25550
                     /gene="radC"
                     /locus_tag="VU534_001070"
     CDS             24870..25550
                     /gene="radC"
                     /locus_tag="VU534_001070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000286923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HEU1513671.1"
                     /translation="MYSISFQEDSLLPRERLAKEGVEALSNQELLAILLRTGTRQASV
                     FEIAQKVLNNLSSLTDLKKMTLQELQSLSGIGRVKAIELQAMIELGHRIHKHETLEME
                     SILSSQKLAKKMQQELGDKKQEHLVALYLNTQNQIIHQQTIFIGSVTRSIAEPREILH
                     YAIKHMATSLILVHNHPSGAVAPSQNDDHVTKLVKEACELMGIVLLDHLIVSHSNYFS
                     YREKTDLI"
     gene            complement(25547..26236)
                     /locus_tag="VU534_001071"
     CDS             complement(25547..26236)
                     /locus_tag="VU534_001071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HEU1513672.1"
                     /translation="MKKPVIGITGNEKTHPDDDIMMSYAAKGFVEGVKDAGGIPIILP
                     IGDQEMACHYISLIDKLILTGGQNVDPKFYGEPKTIDSDDYHLQRDIFELALIKEAIK
                     QKKPIFSVCRGTQLFNVAMGGTLYQDIEDHWQDSSVEYTTQRLVTEPDTVLQEIYGEI
                     SHINSFHHQSIKDLAPNLKVVAHDPKDGIIEAVMSTDDVAFLGVQWHPELLFENRPKD
                     KKLFDYVVNEL"
     gene            complement(26254..26895)
                     /locus_tag="VU534_001072"
     CDS             complement(26254..26895)
                     /locus_tag="VU534_001072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HEU1513673.1"
                     /translation="MKDKQFAIPKATAKRLSLYYRIFKRFHAEKIERANSKQIAEAIG
                     IDSATVRRDFSYFGELGRRGFGYDVKKLMTFFADLLNDNSITNVMLVGIGNMGHALLH
                     YRFHERNKMKIIMAFDLDDHPEVGTQTPDGIPIYGISQIKDKIKDADVKTAILTVPSV
                     KSQEVANLLVDAGVKGILSFSPVHLHLPKDVVVQYVDLTSELQTLLYFMRKED"
     gene            complement(26978..27193)
                     /locus_tag="VU534_001073"
     CDS             complement(26978..27193)
                     /locus_tag="VU534_001073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4649 family protein"
                     /protein_id="HEU1513674.1"
                     /translation="MFELTYKDCYHVERTLKYEDHEALMLTLSGCVTLPDTLYVTSLT
                     FRGKKVYQGLVGDLYRFLSHADFLHQN"
     gene            complement(27201..27548)
                     /locus_tag="VU534_001074"
     CDS             complement(27201..27548)
                     /locus_tag="VU534_001074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1831 domain-containing protein"
                     /protein_id="HEU1513675.1"
                     /translation="MAFEKIIQLKNCRYDYTLSPSVKKFTLKDNTFFETKVGNYELTR
                     LLEKVPNSGEGFQLKIIINKELTGAKINITDKFGLRLVDIFKSEDHHIHQEKFYFLMD
                     SLVERGVFTKSER"
     gene            complement(27553..28668)
                     /locus_tag="VU534_001075"
     CDS             complement(27553..28668)
                     /locus_tag="VU534_001075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEU1513676.1"
                     /translation="MIYLDNAATTPMSAVAISAMTKVMQETHGNPSSIHGHGRQAGKL
                     LREARQELAQLLRTKPQHIFFTSGGTEGNNTTIIGYCLRHQEQGKHIITTAIEHHAVL
                     ETIDYLVQHFGFEATIIQPENQEITAQQIQKALRDDTILVSTMFVNNETGNLLPIAEI
                     GQILKQHPAAYHVDAVQAIGKIPIHSEELGIDFLTASAHKFHGPKGIGFLYASSMDFD
                     SYLHGGDQEQKKRAGTENLPAIVGMVAALKEDLEKQEEHFQHVQNLETAFLAELEGIQ
                     YYLNRGKHHLPYVLNIGFPGQKNDLLLLRLDLAGISISTGSACTAGVVQSSHVLEAMY
                     GANSERLKESLRISLSPQNTVEDLQTLAKTLKEIIGG"
     gene            complement(28678..29637)
                     /locus_tag="VU534_001076"
     CDS             complement(28678..29637)
                     /locus_tag="VU534_001076"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HEU1513677.1"
                     /translation="MSDRKNMKLFALNSNQEIAQKIAQAVGVPLGKLSSRQFSDGEIQ
                     VNIEESVRGYDVYIIQSTSFPVNNHLMELLIMVDACVRASAHSINVVLPYFGYARQDR
                     IACPREPLTAKLVANMLVKAGVDRILTLDLHAVQVQGFFDIPVDNLFTVPLFAKHYCD
                     KGLLGSDVVVVSPKNSGVKRARSLAEYLDAPIAIIDYPQDDATRNEGYIIGDVEGKKA
                     ILIDDILNTGRTFSEASKIVEREGATEIYAVSSHGLFVEGAAELLDNTNIKEILVTDS
                     VATKEKTPKNVCYITASELIGDAIVRIHERKPVSPLFAYNKKK"
     gene            complement(29750..30319)
                     /locus_tag="VU534_001077"
     CDS             complement(29750..30319)
                     /locus_tag="VU534_001077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HEU1513678.1"
                     /translation="MKHLEIELKTLLKKDEYNRLKDQFTGVTPVLQTNYYIDTPDFEL
                     REKKVAMRIRTFEDWAELTLKVPQSVGNMEYNQKLQLKDAENYLSKEELPQGLVLDEL
                     AKHGIQSKNWQVLGCLTTLRYEMKTAIGLMALDQSRYFDITDYELELEVENHEQGKQD
                     FRQFLEKNQISYQKAPSKLVRFVKSMKNS"
     gene            30447..31118
                     /locus_tag="VU534_001078"
     CDS             30447..31118
                     /locus_tag="VU534_001078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HEU1513679.1"
                     /translation="MTLEWEEFLDPYIQAVGELKIKLRGIRKQYRKQNKHSPIEFVTG
                     RVKPIESIKEKMARRGITYATLEHDLQDIAGLRVMVQFVDDVKEVVDILHKRQDMRII
                     QERDYITHRKASGYRSYHVVVEYTVDTINGAKTILAEIQIRTLAMNFWATIEHSLNYK
                     YQGDFPDEIKKRLEITARIAHQLDEEMGEIRDDIQEAQALFDPLSRKLNDGVGNSDDT
                     DEEYR"
     gene            31102..31920
                     /locus_tag="VU534_001079"
     CDS             31102..31920
                     /locus_tag="VU534_001079"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000799053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HEU1513680.1"
                     /translation="MKNTGKRIDLIANRKPQSQRVLYELRDLLKRNQFILNDTNPDIV
                     ISIGGDGMLLSAFHKYENQLDKVRFIGLHTGHLGFYTDYRDFELDKLVTNLQLDTGAR
                     VSYPVLNVKVFLENGEVKIFRALNEASIRRSDRTMVADIVINGVPFERFRGDGLTVST
                     PTGSTAYNKSLGGAVLHPTIEALQLTEIASLNNRVYRTLGSSIIVPKKDKIELIPTRN
                     DYHTISVDNSVYSFRNIERIEYQIDHHKIHFVATPSHTSFWNRVKDAFIGEVDE"
     gene            31917..32813
                     /locus_tag="VU534_001080"
     CDS             31917..32813
                     /locus_tag="VU534_001080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEU1513681.1"
                     /translation="MRFEFIADEHVKVKTFLKKHEVSKGLLAKIKFRGGAILVNNQPQ
                     NATYLLDVGDYVTIDIPAEKGFETLEAIELPLDILYEDDHFLVLNKPYGVASIPSVNH
                     SNTIANFIKGYYVKQNYENQQVHIVTRLDRDTSGLMLFAKHGYAHARLDKQLQKKSIE
                     KRYFALVKGDGHLEPEGEIIAPIARDEDSIITRRVAKGGKYAHTSYKIVASYGNIHLV
                     YIHLHTGRTHQIRVHFSHIGFPLLGDDLYGGSLEDGIQRQALHCHYLSFYHPFLEQDL
                     QLESPLPDDFSNLITQLSTNTL"
     gene            32857..33831
                     /gene="pta"
                     /locus_tag="VU534_001081"
     CDS             32857..33831
                     /gene="pta"
                     /locus_tag="VU534_001081"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HEU1513682.1"
                     /translation="MEVFESLKANLVGKNARIVLPEGEEPRILQATKRLVKETEVIPV
                     LLGNPEKIKIYLEIEGIMDGYEVIDPQHYPQFEEMVSALVERRKGKMTEEDVRKVLVE
                     DVNYFGVMLVYLGLVDGMVSGAIHSTASTVRPALQIIKTRPNVTRTSGAFLMVRGTER
                     YLFGDCAININPDAEALAEIAINSAITAKMFGIEPKIAMLSYSTKGSGFGESVDKVVE
                     ATKIAHDLRPDLEIDGELQFDAAFVPETAALKAPGSTVAGQANVFIFPGIEAGNIGYK
                     MAERLGGFAAVGPVLQGLNKPVNDLSRGCNADDVYKLTLITAAQAVHQ"
BASE COUNT        10298 a         6106 c         7530 g        10183 t
ORIGIN      
        1 aaaacttgat acataaaaat aaaagtctat ataaaggatg gtaaaattcc tgttgtccga
       61 tttggacaat atcctaaata gttacaatat atggtctata ctttttctta ggagaaagct
      121 agatgtacag acgtttgaga gatttgaggg aggatcatga tctgccccaa aagcaaatag
      181 ctacaatact ttcgtttaca aattcagctt atgccaaaat tgaacggggt gagcatgcgt
      241 tgacggctga tgtattggtt aaactctcag atttctatga cgtcagtaca gactatttat
      301 tgggattaac tgattttcct gataaaattc gctttagaaa ataatctcct caatttcata
      361 gagtttgaaa atgagtgaga ttttttattt gccctttgac aactgaatag cctaaaatgg
      421 tactttcctc atttgtggag caaatttgaa tggctcgcca tgataagagc gattttaaaa
      481 tcatcaataa aatagagcga tactttatat gccatgatac aaatgatata caatgatact
      541 tctgaccgtt cagcctgcca acgtaaaaga gcagcaagtg aaattcttat gatgacttca
      601 tcagtcatgc cacgttgaat gtgtgagttt gttagataaa cgcaattaat cctcaaaagg
      661 ttccccgaac cttttgagtt ctacagacgc atcacgtgga gtgtgtaagc ttgttgctaa
      721 aagcgtaaaa accttggaac gaaaggaata atagactttc tgcgaaacaa aaatataata
      781 caataaaact atgaatgatg aagcaagtaa acaattgagc gatagccgtt tcaagatcct
      841 tgtaggtgtt cagcgcacga cttttgaaga gatgttagct gtgttaaaaa cagcttatca
      901 acgtaaacgc gcaaaaggtg gacgaaaaag caaattaagc ctagacgatc tccttatggt
      961 aactattcaa tacatgcgag aatagagcac ttatgaacaa attgcggctg attttggcat
     1021 tcacgaaagc aacttaatcc gtcggagtca atgggttgaa gcaactctta ttcaaaatgg
     1081 ttttacgatt tcaaattctg ccttaattct gtaaaaacag taaaattcga aggattgtaa
     1141 ggtaagagtt tttttctttc tgaaaaaatg gtataatagc aatcaaaact agaaaataaa
     1201 acggaatttg gaacagattt gtctgtatcc tagtagagtg gtgatactat gaagattagt
     1261 aagaggcact tattaaatta ttccatcttg attccctact tgcttttatc tattttgggc
     1321 ttgattgtgg tctattcgac caccagtgct attttaattg aagaaggcaa gagcgccttg
     1381 cagttggttc gaaaccaagg aatcttttgg attgttagtt tgatactgat tgccttaatt
     1441 tataaattga gactagattt tttgagaaat gagcgactaa tcattttagt tatattaata
     1501 gaaatgcttt tattgttctt ggctcgtttt attggtattt ccgtaaacgg ggcatacggt
     1561 tggatttcgg ttgcaggaat aactattcag ccagctgagt acttaaaaat cattattatt
     1621 tggtatttag ctcaccgatt ctccaaacag caagaagaaa tagctactta tgattttcaa
     1681 gttttgactc aaaatcaatg gcttccccgt gcttttaatg attggcgatt cgttctccta
     1741 gttctgattg gaagtttggg aattttccct gatttaggaa atgcgactat tttagtcttg
     1801 gtttccttga ttatgtatac agttagtgga atcgcttatc gctggttttc aaccattctg
     1861 gcgctcgtat ctgccgcttc tgtctttgtc ttgaccacta tcagcctaat cggtgttgag
     1921 accttttcaa aaattccagt attcggctat gtagccaagc gctttagtgc cttttttaat
     1981 ccttttgccg atcgtgctga tgcaggtcac cagttagcta attcttattt tgccatggtc
     2041 aatggcggtt ggtttggtct aggtcttgga aactcgattg aaaaacgagg ttatttgcca
     2101 gaagctcata cagactttgt cttttctatc gtgattgaag aatttggctt tgttggtgcc
     2161 agtcttattt tagctctctt gtttttcatg attttgcgga ttatcttggt cggtatccga
     2221 gcggagaatc ctttcaatgc catggttgca ctcggtgtcg gagggatgat gttggttcag
     2281 gtatttgtca atatcggagg gatttcgggc ttgattccat ctacaggagt gactttcccc
     2341 ttcttatccc agggtggaaa tagtcttcta gtcttatcag tggcagtagc ctttgtctta
     2401 aatattgatg ccagtgaaaa acgcgctaaa ttgtaccgag aattggaaaa tcaaccaatg
     2461 aaccttctgt tgaagtagga taaagaaagg atagtttatg tctcttcaaa aattagaaaa
     2521 ttatagtaat aaaagtgttg tgcaagaaga agtcttgatt ctaacagaat tactggaaga
     2581 tattactaaa aatatgcttg ccccagagac ctttgaaaaa ataatacagt tgaaagaatt
     2641 atcaacgcag gaagattatc aaggtctaaa ccgtctagtg actagcttat caaatgatga
     2701 aatggtctat atttcacgct atttctctat cttgcctctt ttgattaata tttcagagga
     2761 tgtggattta gcttatgaaa tcaatcatca aaataatatt gatcaggact atttaggtaa
     2821 attatctaca acgattaaat tggtagcaga aaaggaaaat gccgttgaga tcctagaaca
     2881 cttgaatgtt gtccctgttt tgacagccca tccaacacaa gtgcaacgca aaagtatgtt
     2941 ggatttaaca aatcatattc atagtctttt gcgtaaatac cgtgatgtta agttggggtt
     3001 gatcaataaa gataaatggt acaatgattt gcgtcgttac atcgaaatta tcatgcagac
     3061 agacatgatt cgtgagaaaa aattaaaagt gactaacgaa atcacgaatg ctatggaata
     3121 ttataacagc tcctttttga aagctgtacc tcatttgacg acggagtata agcgcttagc
     3181 gcaagcgcat ggtctgaatt taaaacaggc taaaccaatc accatgggta tgtggatagg
     3241 tggtgaccgt gatggaaatc catttgttac agcaaagacc ttgaagcagt ctgcactcac
     3301 tcagtgtgaa gtcatcatga actactatga taaaaagatt taccaacttt atcgtgaatt
     3361 ttctctttca actagcattg tcaacgtcag caagcaagtc agagaaatgg ctcgtcaatc
     3421 caaggataac tcgatttacc gcgaaaaaga gctttaccgt cgtgccttgt ttgatattca
     3481 atcaaaaatt caggcaacta aaacctatct gattgaggat gaagaagttg ggactcgtta
     3541 tgaaaccgcc aatgatttct acaaggattt gattgccatt cgagattctc tactagaaaa
     3601 taagggcgag tccttgattt caggtgattt tgtggaatta ttgcaggcag tagagatatt
     3661 tggtttttac ttagcatcaa ttgatatgcg acaagactct agcgtctatg aagcctgtgt
     3721 ggcagaactc ttgaaatcag caggaattca ttctcgttat agcgagttga gcgaagaaga
     3781 aaagtgtgac cttctcttga aagaattaga agaagatccc cgaattcttt ctgcgactca
     3841 cgcagaaaaa tcagaattat tagcaaaaga attagctatt tttaagacgg ctcgtgtttt
     3901 gaaagataag ttgggagatg atgtcatccg tcagaccatc atttcacatg caaccagcct
     3961 ttctgatatg ctagaattag ctattctgtt aaaagaagta ggactggtgg atacggaaag
     4021 ggcgcgtgtt cagattgttc ccctttttga aacaattgaa gacttggatc attcagagga
     4081 aacaatgaga aaatatcttt ctcttagcct tgccaaaaaa tggattgact cacgaaataa
     4141 ctaccaagaa atcatgcttg gctactctga cagtaataaa gatggcggtt acttgtcatc
     4201 atgttggacc ctctacaagg ctcaacaaca attgactgct attggagatg aatttggcgt
     4261 taaggttacc ttcttccatg gtcgtggtgg tactgtcggt cgtggtggtg ggccaaccta
     4321 tgaagccatt acatctcaac cgctcaagtc tatcaaggat cgtatccgct tgacggagca
     4381 gggtgaagta attgggaata aatacggtaa caaagacgcc gcttactata accttgaaat
     4441 gctagtatcg gcagctatta accgtatgat tactcagaag aagagcgata ccaatacccc
     4501 aaatcgttat gaaaccatta tggatcaagt agtggaccgt agttacgata tctaccgtga
     4561 tttggtcttt ggtaatgagc atttctatga ttatttcttc gagtcaagtc caatcaaggc
     4621 tatttcaagt tttaatattg gttctcgtcc agccgctcgt aagactatta ctgaaatcgg
     4681 tggtttgcgt gccatccctt gggtattctc atggtcacag agtcgtgtta tgttccctgg
     4741 atggtacggg gttggttcaa gcttcaagga atttatcaat aaaaatccag agaatattgc
     4801 tatcttacga gatatgtacc aaaattggcc tttcttccaa tcgcttcttt caaatgttga
     4861 tatggttttg tcaaaatcaa atatgaatat tgcttttgaa tatgctaaac tttgtgaaga
     4921 cgagcaagtt aaggccatct atgagactat tttaaatgaa tggcaagtta ctaagaacgt
     4981 tatcttggct attgaaggac atgacgaact cttagctgac aatccatatc taaaagctag
     5041 tctggattac cgtatgcctt actttaatat tctcaactat attcagttgg agttgattaa
     5101 acgccaacgt cgtggagaat tgtccagtga tcaagaacga ttgattcata tcaccatcaa
     5161 cggaattgcg acaggattgc gtaattcagg ttgataattt tcaagagtga atgctaaaag
     5221 tgaatatcaa aaaaattcta atagactatt gacaagtagt ttaaaaatga tataatttaa
     5281 ccattcagaa aagtaatcat acaaactttt tagagagtct gtggtagctg aaaacagata
     5341 agtggcaatg atgaaaattg ggctgaatgc tatttagaat ttgaaattat aaaaattcgg
     5401 taagcacacc ttacagtgca tctcgttatt gcgagactga gcgataggga aattccctat
     5461 aattgaggtg gtaccgcgca tcgacgtcct cacacaagtt ttttgtgtga ggattttttt
     5521 gatggaggtt agtatggaaa gaaaacgatg gcgtcgcttg tttagataag tgaaatatgt
     5581 taaaggaaat aaaaaggaga aacagaatga aaaataaacg tttaattgga attattgctg
     5641 cattagcagt cttagtagca ggaagcttga tttattcttc aatgaataaa tcagaagctc
     5701 agaataataa ggatgagaag aaaataacca agattggtgt gcttcaattt gtgagccatc
     5761 catcccttga tttgatttat aaagggatcc aagatggact tgcagaagaa ggatataaag
     5821 atgatcaagt taaaattgat tttatgaact cagaaggtga ccaaagtaag gttgcgacaa
     5881 tgagtaaaca attggttgca aatgggaatg accttgtggt tggtatcgca acaccagcag
     5941 cccaagggtt ggctagtgca acaaaagacc taccggttat catggccgct attacagacc
     6001 caattggtgc taacttggtt aaagatttga aaaaaccagg tggcaacgtt acaggggtat
     6061 ctgaccacaa tccagctcaa caacaagttg aactcatcaa ggctctgaca ccgaatgtga
     6121 aaacaatcgg agctctttac tcaagtagcg aagacaattc aaaaacacag gtcgaagaat
     6181 ttaaggctta tgctgaaaaa gcaggtctga cagtggaaac atttgcagtt ccttcaacaa
     6241 atgaaattgc ctcaactgtc actgttatga ctagcaaggt agatgctatt tgggttccaa
     6301 ttgataacac cattgcatca ggatttccaa cggttgtctc tagcaatcaa agttctaaga
     6361 aaccaattta tcccagtgcg acagctatgg tagaagtagg tggtttggca tcagttgtaa
     6421 ttgaccaaca tgaccttggt gtggcaacag gtaaaatgat tgtgcaagtc ttgaaaggtg
     6481 caaaaccagc cgatacccca gtcaatgtct tttcaactgg taagtcagtc atcaataaaa
     6541 aaatagcaca agaactaggt attactattc ctgagtctgt tctcaaagaa gcaggacaag
     6601 tcatcgaata aataaggtag ggaggaggag actcttccca ttttttaaaa agatgaatat
     6661 agaaaggatt aaataaaata tgattgtttc cattatttct caaggatttg tctgggctat
     6721 tctaggtctg ggaatcttta tgacatttag gattttaaac tttccagata tgacgacaga
     6781 aggttccttc cctcttgggg gagctgttgc tgtcactttg ataaccaaag gcgtgaaccc
     6841 atttttagcg acacttgttg ctgtaggagc aggttgtttg gctggaatgg cagcaggcct
     6901 tctttataca aaagggaaga tcccaacctt gctctcaggg attttggtga tgacttcttg
     6961 tcactcaatc atgctcttga ttatgggacg tgcgaattta ggcctgcttg gaaccaagca
     7021 aattcaggat gttttgcctt ttgattcgga tttgaatcaa ctcttgacag gtctcatctt
     7081 tgtgagtatt gttattgctc tcatgctctt tttcttggac actaaactcg gacaagccta
     7141 tattgctaca ggggataatc ctgatatggc tagaagtttc gggattcata ctggacgcat
     7201 ggagctcatg ggcttggtct tatcaaatgg tgtgattgcc cttgcaggtg ccctcattgc
     7261 tcagcaagaa ggttatgccg atgtgtctcg agggatcggg gttatcgttg tggggcttgc
     7321 aagtttgatt attggagaag ttattttcaa gagtttgagc ttggcagagc gtttggttac
     7381 tatcgttgta ggttctatcg cttatcaatt tttagtgtgg gcagttatcg cacttggctt
     7441 taatacaagt taccttcgtt tatacagtgc cttgatttta gcagtctgcc tcatgattcc
     7501 aacatttaag caaacaatct tgaaaggagc caagttaagc aaatgacagc aattgtagaa
     7561 ttaaaaaatg caaccaaaat cgttaaaaat ggctttgatg aagaaaagat tattttaaat
     7621 gatgtttcct tagaaatttt tgaacgggac tttatcacga ttttgggcgg aaatggtgct
     7681 ggaaaatcaa ctctctttaa cactatagca gggaccttat cactaactag tggaactatc
     7741 cgtattttag gtgaagatct cactaagttt tcacccgaga agcgtgccaa gtacctgtct
     7801 cgtgtcttcc aagatccaaa gatggggaca gctccccgta tgacggtcgc tgaaaatctt
     7861 ttaatcgcca agtttcgtgg tgaaaagcgt ggattgttac cacgacgctt gactagctat
     7921 aaggatgaat ttcaggcaac cattgaaaaa gtaggaaatg gtcttgagaa acacttgaat
     7981 acaccgattg agttcttatc aggtggacaa agacaggctt tgagtctctt gatggcaacc
     8041 ttgaagcgac ctgaattact cctgttagat gagcatactg ctgccctgga tccaaagact
     8101 agtgttgctt tgatggaatt gacagatgaa tttgttaaga aagatcagct aacagccctt
     8161 atgattactc atcatatgga agatgctctc aaatacggca atcgcttgat tgtcatgaaa
     8221 gaaggacgaa ttatccaaga tttaaaccaa gaagaaaaag caaaaatgaa aatctctgat
     8281 tattatcaac tctttgaata aagtagggaa aatgagtgaa atggtttact ttttttctga
     8341 aataaagtat actatataaa gtaaactatg ataacatgga ggtattgtgt atggttgaca
     8401 aacaagtcat tgaagaaatc aaaaacaatg ccaacattgt ggaagtcata ggagatgtga
     8461 tttctttaca aaaggcagga cggaactatc tagggctctg tccttttcat ggtgaaaaaa
     8521 caccatcttt caatgttgta gaggacaagc agttttatca ctgtttcggt tgtggtcgct
     8581 caggtgatgt ctttaagttc atcgaggagt accaaggggt tccctttata gaagcagtcc
     8641 aaatcttagg tcagcgtgtt ggaattgagg ttgaaaaacc gctttatagt gagcagaagt
     8701 cagcctcacc tcaccaagct ctttatgata tgcacgaaga tgcagccaaa ttttaccatg
     8761 ctattctcat gacaacgact atgggcgaag aggccagaaa ttacctttat cagcgggggt
     8821 tgacagatga agtgcttaaa catttttgga ttggtttagc acctccagaa cgaaactatc
     8881 tctatcaacg tttgtctgat cagtatcgtg aagaggattt actggattca ggcctgtttt
     8941 atctctcgga tgccaatcaa tttgtagaca cctttcacaa tcgcattatg tttcccctga
     9001 caaatgacca aggaaaggtc attgccttct caggtcgtat ctggcaaaaa acggattcac
     9061 aaacttctaa gtataaaaac agccgatcga ctgcaatttt taacaaaagt tacgaattat
     9121 atcatatgga tagggcaaaa agatcttctg gaaaagctag tgagatttac ctgatggaag
     9181 gattcatgga tgttattgca gcctatcggg ctggaatcga aaatgctgtg gcgtcgatgg
     9241 gaacagcctt gagtcgagag catgttgagc atctgaaaag gttaaccaag aaattggttc
     9301 ttgtttacga tggagataag gctgggcaag ccgcgacatt gaaagcattg gatgaaattg
     9361 gtgatatgcc tgtgcaaatc gtcagcatgc ctgataactt ggatcctgat gagtatctac
     9421 aaaaaaatgg tccagaagac ttggcctatc tattaacgaa aactcgtatt agtccgattg
     9481 agttctacat tcatcagtac aaacctgaaa acagtgaaaa tctgcaggct cagattgagt
     9541 ttcttgaaaa aatagctccc ttgattgttc aagaaaagtc catcgctgct caaaacagct
     9601 atattcatat tttagctgac agtctggcgt cctttgatta tacccagatt gagcagattg
     9661 ttaatgagag tcgtcaggtg caaaggcaga atcgcatgga aggaatttcc agaccgacgc
     9721 caatcaccat gcctgtcacc aagcagttat cggctattat gagggcagaa gcccatctac
     9781 tctatcggat gatggaatcc cctcttgttt tgaacgatta ccgtttgcga gaagactttg
     9841 catttgctac acctgaattt caggtcttat atgacttgct tggccagtat ggaaatcttc
     9901 ctccagaagt tttagcagag cagacagagg aagttgaaag agcttggtac caagttttag
     9961 ctcaggattt gcctgctgag atatcgccgc aggaacttag tgaagtagag atgactcgaa
    10021 acaaggctct cttgaatcag gacaatatga gaatcaaaaa gaaggtgcag gaagctagcc
    10081 atgtaggaga tacagataca gccctagaag aattggaacg tttaatttcc caaaagagaa
    10141 gaatggagta ataatggcaa caaaacaaaa agaagtaaca acatttgacg tacaggtagc
    10201 agaatttatc cgtaatcata agcaaaaagg gacagcaaca gatgatgaaa tcaatgcaag
    10261 tctggttatt ccttttacct tggacgctga tgggattgaa gatctcttgc aacggattca
    10321 ggatgcaggc atttctatca cagataacga aggaaatcca agtgcgcgtg ttctcagcaa
    10381 tgaagaagaa ccagaactca gcgatgagga cttgattggg tcaacttctg ctaaggtcaa
    10441 tgaccctgtc cgtatgtact tgaaagaaat aggggtcgtt cctctcttga ccaatgaaga
    10501 ggagaaagag ttggcactgg ctgttgaagc tggtgatatc gaagccaaac aacgtcttgc
    10561 ggaagccaat cttcgtttgg ttgtttccat tgccaaacgc tatgtcggtc gtggtatgca
    10621 gttccttgac ttgattcaag aaggaaatat gggcttgatg aaggcggttg acaagtttga
    10681 ctattctaaa gggttcaagt tttcaactta tgcaacttgg tggattcgtc aggctatcac
    10741 tcgtgctatt gcggaccaag ctcgtaccat ccgtatccca gttcacatgg ttgaaactat
    10801 caataaattg gttcgtgaac agcggaatct ccttcaagaa ttggggcaag atccgacacc
    10861 agaacagatt gctgaacgaa tggatatgac acctgataag gttcgtgaaa tcttgaagat
    10921 tgcccaagaa ccagtatctc ttgaaactcc tatcggtgaa gaggacgata gccaccttgg
    10981 agactttatc gaagatgaag tgattgaaaa tccagtggat tatacgactc gtatcgtctt
    11041 gcgtgagcaa ttggatgaaa tcttagatac tcttacagac cgtgaagaaa atgttctgcg
    11101 tctacgtttt ggactagatg atggaaaaat gcgcacactt gaagatgtgg ggaaagtctt
    11161 taacgtaact cgtgagcgta tccgtcagat tgaagcaaag gctttgagaa aactacgcca
    11221 accaagtcgt agcaaaccgc ttcgtgattt tattgaagac taagagtgag gaaaatatgg
    11281 cttatacaga agagcaaatt gaaaacatca aaacacggat tttaacagcc ttggaagaag
    11341 tcatcgaccc tgagttggga atcgatattg tcaatcttgg tttgatctat gagattcgtt
    11401 ttgacggtga cacagggcaa acagagattg acatgacttt gacaactatg ggttgtccct
    11461 tagcagacct tttgacagac cagatttatg atgctatgat agaggttcca gaagtaacgg
    11521 atactgaggt taaattagtc tggtatccag cctggacagt tgaaaaaatg agtcgctatg
    11581 cccgcattgc cctaggcatt aagtaaacat ataaaagcat gtgagagact gttggaaaag
    11641 cgaggaaatt tcccctcttt tcctctagtc tctcctttct tttgctgatt ttattcaaag
    11701 aaaatgatat aatagtagtt atggagaaaa agaaattacg catcaatatg ttgagttcaa
    11761 gtgagaaagt agcaggacag ggagtttcag gtgcttaccg tgaattagtt cgtcttcttc
    11821 accgtgctgc caaggaccaa ttgattgtta cagaaaatct tccaatcgag gcagatgtga
    11881 ctcactttca tacgattgat tttccctatt atttatcaac cttccaaaag aaacgctcag
    11941 ggagaaagat tggctatgtg catttcttgc cagctacact tgagggaagt ttgaaaattc
    12001 catttttctt aaagggaatt gtgaaacgct atgtattttc tttttacaac cggatggagc
    12061 acttggttgt ggtcaatcct atgtttattg aggatttggt agcagctggt attccacgtg
    12121 aaaaagtgac ctatattcct aactttgtca acaaggaaaa atggcatcct ctaccacaag
    12181 aagaggtagt cagactgcgc acagatcttg gtcttagtga caatcagttt atcgtagtag
    12241 gtgctgggca agttcagaaa cgtaaaggga ttgatgactt tatccgtctg gctgaggaat
    12301 tgcctcagat tacctttatc tgggctggtg gcttctcttt tggtggtatg acagatggtt
    12361 atgaacacta taagaaaatt atggaaaatc cccctaaaaa tttgattttt ccaggcattg
    12421 tatcgccaga gcggatgcgc gaattgtatg ctctagcgga tcttttcttg ttgcctagtt
    12481 acaatgagct ctttcctatg actattttag aagctgcgag ttgtgaggct cctattatgt
    12541 tgcgtgattt agatctctat aaggtgattt tggagggaaa ttatcgggcg acagcgggta
    12601 gagaagagat gaaagaggct attttggaat atcaagcaaa tcctgctgtc ttaaaagatc
    12661 tcaaagaaaa ggctaagaat atttccagag agtattctga agagcatctg ttacaaatct
    12721 ggttggactt ttatgagaaa caagccgctt tagggagaaa gtaaaaagtg aggtaatcta
    12781 tgcgaattgg tttatttaca gatacctatt ttcctcaggt ttctggtgtt gcgaccagta
    12841 ttcgaacctt gaaaacagaa cttgaaaagc agggacatgc tgtttttatc tttacgacga
    12901 cagataagga tgtcaatcgc tacgaagatt ggcaaattat ccgcattcca agtgttcctt
    12961 tctttgcttt taaggatcgt cgctttgcct accgaggttt tagcaaggca cttgaaattg
    13021 ctaaacagta tcagctagat attatccata ctcagacaga attttctctt ggcctgttgg
    13081 ggatttggat tgcgcgtgaa ttgaaaattc cagtcatcca tacctatcac acccagtatg
    13141 aagactatgt ccattatatt gctaagggga tgttgatccg gccgagtatg gtcaagtatc
    13201 tggttagagg tttcctgcat gatgtggatg gggttatttg ccctagtgag attgtccgtg
    13261 acttgctatc tgattataag gtcaaggttg aaaaacgggt cattcctact gggattgaat
    13321 tagccaagtt tgagcgtccg gaaatcaagc aggaaaattt gaaagaactg cgtagtaaac
    13381 tagggattca agatggtgaa aagacgttgc ttagtctttc gagaatctcc tatgaaaaaa
    13441 atattcaagc agttttagca gcctttgctg atgttctgaa agaggaagac aaggttaaac
    13501 tggtagtagc tggggatggc ccttatctga atgacctcaa agagcaagcc cagaacctag
    13561 agattcaaga ctcagtcatc tttacaggga tgattgctcc tagtgagacg gctctttact
    13621 ataaagcggc ggatttcttc atttcggcat cgacaagcga aacgcaaggt ttgacctact
    13681 tggaaagctt agccagtgga acacctgtca ttgctcacgg aaatccttat ttgaacaacc
    13741 tcatcagtga taaaatgttt ggaaccttgt actatggaga acatgatttg gctggtgcta
    13801 ttttggaagc cctgattgca acaccagaca tgaacgagca taccttatca gagaaattgt
    13861 atgagatttc agctgagaac tttgggaaac gagtgcatga gttttatctg gatgccatta
    13921 tttcaaataa cttccagaaa gatttggcta aagatgatac ggtcagtcag cgtatcttta
    13981 agacagtttt gtatcttcag caacaggtgg ttgctgtacc tgtaaaagga tctagacgca
    14041 tgttgaaggc ttcaaaaaca cagttgatca gtatgagaga ctattggaaa gaccatgaag
    14101 aatagaaaga ggaacagcta tgaaaaaaac aattaatgag aagcggtcgt gataaaaaga
    14161 ttgcgggtgt ttgtgctggg gtggcccatt atctggatat ggatccgact atcgttcaag
    14221 tcatttgggg tgttcttact tgctgttacg gagctggaat tgtagcttac attattttat
    14281 ggattatcgc accagtagca actgactatt gaaaactagc tcaattcatg ctaagataat
    14341 agaaaataga atgtaacgaa ggagagaaaa atggcatttg gagataatgg aaatcgtaaa
    14401 aaaactatgt ttgagaaaat aaccttgttt atcgtgatta tcatgctagt agcaagttta
    14461 ttgggaattt ttgcaactgc aattggtgcc ctcagtaatc tataaaatag attcaagaaa
    14521 atttagtgac tgggatttcc cagccctttt ttaaagtgag aagaaataat gagtatgttt
    14581 ttagatacag ctaagattaa ggtcaaggct ggtaatggtg gcgatggtat ggttgccttt
    14641 cgtcgtgaaa aatatgtccc taatggaggc ccttggggtg gtgatggtgg tcgtggaggc
    14701 aatgtggtct tcgttgtaga cgaaggacta cgtaccttga tggatttccg ctacaatcgt
    14761 catttcaagg ctgattctgg tgaaaaaggg atgaccaaag ggatgcatgg tcgtggtgct
    14821 gaggacctta gagttcgagt accacaaggt acgactgttc gtgatgcgga gactggcaag
    14881 gttttaacag atttgattga acatgggcaa gaatttatcg ttgcccacgg tggtcgtggt
    14941 ggacgtggaa atattcgttt cgcgacacca aaaaatcctg caccggaaat ctctgaaaat
    15001 ggagaaccag gtcaggaacg tgagttacaa ttggaactaa aaatcttggc agatgtcggt
    15061 ttagtaggat tcccatctgt agggaagtca acacttttaa gtgttattac ctcagctaag
    15121 cctaaaattg gtgcctacca ctttaccact attgtaccaa atttaggtat ggttcgcacc
    15181 caatcaggtg aatcctttgc agtagccgac ttgccaggtt tgattgaagg ggctagtcaa
    15241 ggtgttggtt tgggaactca gttcctccgt cacatcgagc gtacacgtgt tatccttcac
    15301 atcattgata tgtcagctag cgagggccgt gatccatatg aggactacct agctatcaat
    15361 aaagagctgg agtcttacaa tcttcgcctc atggagcgtc cacagattat tgtagctaat
    15421 aagatggaca tgcctgagag tcaggaaaat cttgaagact ttaagaaaaa attggctgaa
    15481 aattatgatg aatttgaaga gttaccagct atcttcccaa tttctggatt gaccaagcaa
    15541 ggtctggcaa cacttttaga tgctacagct gaattgttag acaagacacc agaatttttg
    15601 ctctacgacg agtccgatat ggaagaagaa gcttactatg gatttgacga agaagaaaaa
    15661 gcctttgaaa ttagtcgtga tgacgatgcg acatgggtac tttctggtga aaaactcatg
    15721 aaactcttta atatgaccaa ctttgatcgt gatgaatctg tcatgaaatt tgcccgtcag
    15781 cttcgtggta tgggggttga tgaagccctt cgtgcgcgtg gagctaaaga tggggatttg
    15841 gtccgcattg gtaaatttga gtttgaattt gtagactagg agactggtat gggagataaa
    15901 ccgatatctt tccgagatgc ggatggtaat tttgtttccg ccgcagacgt ttggaatgaa
    15961 aagaaattgg aagaactatt taatcgtctc aatccaaatc gtgccttgag attggcacga
    16021 actaaaaagg aaaatccatc tcagtaaaga agctaaaaaa tcccgtgcct catcagacac
    16081 gggattttgt ggtacgacag gcatgtatag caaactgaat ctggaatagc acagcatatc
    16141 ttctaaaata tagtaaaatg aaatgagaac aggacaaatc gatcaggaca gtaaaatcga
    16201 tttctaacaa tgttttataa gcagagatgt actattctag tttcaatcaa ctatattgtt
    16261 ataaattgat ttgaatttca aaattaaatt gtttgattct tatttcaatt tgttatagta
    16321 tatctgatgt caaagttctc ggcgagtcaa atagcgattc ccaagcctga ctatcgtgag
    16381 gtagcggatt aaaatggtct ggggatagac cgttttaagt ctgacgctgg aaataagaat
    16441 tgtcagaaga agggatagcg aaatcgtggc tctacgaaca ggaacgtgat aataaggcgt
    16501 atatagcgga taagagggca tcaaactcta aagtccaaaa aggtagtcgt aacctatatg
    16561 cgtaaatcac gagagtaatt gaattcgtac taagattttc tattttcact gtaacctttt
    16621 aacgccctta tatcttgtat acacgaggaa agatgtacga cttatcccgt gaggtctatc
    16681 actataaaga gaaaacgaca gatagaagtg atcctgagtc acggttatct gtctgatagg
    16741 acggtatgta taaaacgctt ctgtgaactg agagaagggg gagaagttct tgctaaaatt
    16801 tagttgaaca gccgtattcc gatacttaga taagagatct agtcttagct cctactcagt
    16861 tttaggggat aaaaaagggg caatagcgat tcgagaaaga ttatactctt cgaaaatctc
    16921 ttcaaatcac gtcaatatcg ccttgtcgta tgtgtaggat actgactacg tcagttccat
    16981 ctacaacctc aaaacagtgt tttgagcaac ctgcggctag tttcctagtt tgatctttga
    17041 ttttcattga gtattagtaa ttcagttact aactcgtcaa ctctgattta tccaataaaa
    17101 ttgaaaagga tggaaaaaag gataaattta tgatatactt tattttgaag accttattag
    17161 aaatcttgaa agagtattga aaacttagaa tgagaaaaat tgttatcaat ggtggattac
    17221 cactgcaagg tgaaatcact attagtggtg ctaaaaatag tgtcgttgcc ttaattccag
    17281 ctattatctt ggctgatgat gtggtgactt tggattgcgt tccagatatt tcggatgtag
    17341 ccagtcttgt cgaaatcatg gaattgatgg gagctactgt taagcgttat gacgatgtat
    17401 tggagattga cccaagaggt gttcaaaata ttccaatgcc ttatggtaaa attaacagtc
    17461 ttcgtgcatc ttactatttt tatgggagcc tcttaggccg ttttggtgaa gcgacagttg
    17521 gtctaccggg aggatgtgat cttggtcctc gtccgattga cttacacctt aaggcgtttg
    17581 aagctatggg tgccactgct agctacgagg gagataacat gaagttatct gctaaagata
    17641 caggacttca tggtgcaagt atttacatgg atacggttag tgtgggagca acgattaata
    17701 cgatgattgc tgcggttaaa gcaaatggtc gtactattat tgaaaatgca gcccgtgaac
    17761 ctgagattat tgatgtagct actctcttga ataatatggg tgcccatatc cgtggggcag
    17821 gaactaatat catcattatt gatggtgttg aaagattaca tgggacacgt catcaggtga
    17881 ttccagaccg cattgaagct ggaacatata tatctttagc tgctgcagtt ggtaaaggaa
    17941 ttcgtataaa taatgttctt tacgaacacc tggaagggtt tattgctaag ttggaagaaa
    18001 tgggagtgag aatgactgta tctgaagaca gcatttttgt cgaggaacag tctaatttga
    18061 aagcaatcaa tattaagaca gctccttacc caggctttgc aactgatttg caacaaccgc
    18121 ttacccctct tttactaaga gcgaatggtc gtggtacaat tgtcgatacg atttacgaaa
    18181 aacgtgtaaa tcatgttttt gaactagcaa agatggatgc ggatatttcg acaacaaatg
    18241 gtcatatttt gtacacgggt ggacgtgatt tacgtggggc cagtgttaaa gcgaccgact
    18301 taagagctgg ggctgcacta gtcattgctg ggcttatggc tgaaggtaaa actgaaatta
    18361 ccaatatcga gtttatctta cgtggttatt ctgatattat cgaaaaatta cgtaatttag
    18421 gagcggatat tagacttgtt gaggattaaa ccgtagaggt gtttatgaat atttggacca
    18481 aattagcaat gttttctttt tttgaaacgg atcgcttgta tttgcgtcct ttctttttta
    18541 gtgatagtca ggacttccgc gagatagctt caaatccaga aaatcttcaa tttattttcc
    18601 caacgcaggc aagtctggaa gaaagtcaat atgcactggc caattacttt atgaagtccc
    18661 ctttgggagt gtgggcaatt tgtgaccaga aaaatcaaca aatgattggt tctattaaat
    18721 ttgagaagtt agatgaaatc aaaaaagaag ctgagcttgg ctattttttg agaaaagatg
    18781 cttggtcgca aggatttatg acagaggttg ttagaaaaat ttgtcagctt tcttttgagg
    18841 aatttggctt aaaacaatta tttatcatta cccaccttga aaataaagct agccaaagag
    18901 ttgctcttaa gtctggattt agtttgttcc gtcagtttaa gggaagtgat cgttacacaa
    18961 gaaaaatgcg ggattatctt gaatttcggt atgtaaaagg agagttcaat gagtaagcat
    19021 caggaaattc taagctattt ggaggaatta ccagtaggta aaagggtcag tgttcgtagc
    19081 atttcgaatc atctaggagt tagtgatgga acagcctatc gggctattaa agaagctgaa
    19141 aaccgtggaa ttgtggagac ccgtcctaga agtggaacaa ttcgtgttaa atcccagaaa
    19201 gttgctatag agagattaac gtttgctgaa attgcagaag tgacttcttc tgaggttctg
    19261 gctgggcaag aaggtttaga gagagaattt agtaagtttt caattggtgc catgactgaa
    19321 caaaatatct tgtcttacct tcatgatggg gggctcttga ttgtcggaga ccgaacccgt
    19381 attcagttgc tagccttgga aaatgaaaat gcagttctgg ttacaggggg atttcaggtt
    19441 catgatgatg tgcttaaact ggccaatcaa aaagggattc ctgttctaag aagtaagcat
    19501 gataccttta ccgtcgcgac catgatcaat aaagccttgt caaatgtcca aatcaagact
    19561 gatattctga cagttgagaa actttatcgc cctagtcatg agtatggttt tctgagagag
    19621 acagatacag ttaaagatta tttggacttg gttcgtaaga atcgtagcag ccgtttccct
    19681 gttatcaatc aacatcaggt cgttgttggt gttgtaacca tgagagacgc tggtgataaa
    19741 tcaccaagca cgacaattga taaggttatg tctcgtagtc tatttttggt tggattatcg
    19801 acaaatattg ccaatgtgag tcaacggatg atcgcagaag actttgaaat ggtaccagtt
    19861 gttcgaagca atcaaacttt gcttggcgtt gtgacgcgac gagatgtcat ggagaagatg
    19921 agccgttccc aagtttcggc tctaccaact ttttctgagc agattggaca aaagctctct
    19981 tatcaccatg atgaagtagt cattacagtg gaacccttta tgctagaaaa aaatggagtt
    20041 ttggctaatg gtgtattggc agaaattctg acccacatga cccaagattt agttgttaat
    20101 agtggtcgca atctcattat cgagcagatg ctgatctact ttttgcaggc tgttcagata
    20161 gatgatatat tgcgcattca ggcacggatt attcatcata cgagacggtc agctataatt
    20221 gattacgata tttatcatgg tcaccagatt gtttcaaaag caaatgtgac tgttaaaatt
    20281 aattagaaac taggagaaaa gatgataaca ttaaaatcag ctcgtgaaat cgaagctatg
    20341 gacaaggctg gtgattttct agcaagtatt catataggct tacgtgattt gattaagcca
    20401 ggcgtagata tgtgggaagt tgaagaatat gtccgccgtc gttgtaaaga agaaaatttc
    20461 cttccacttc agattggggt tgacggtgcc atgatggact atccttatgc tacctgttgc
    20521 tctcttaacg atgaagtggc tcacgctttc cctcgtcatt atatcttgaa agatggtgat
    20581 ttgctcaaag ttgatatggt tttgggaggt cccattgcta aatctgacct aaatgtctca
    20641 aaattaaact tcaacaatgt tgaacaaatg aaaaaataca ctcagagcta ttctggtggt
    20701 ttagcagact catgttgggc ttatgctgtt ggtacaccgt ccgaagaagt caaaaacttg
    20761 atggatgtaa ccaaagaagc tatgtacaag ggtattgagc aagctgttgt tggaaatcgt
    20821 atcggtgata tcggtgcggc tattcaagaa tacgctgaaa gtcgtggtta cggtgtagtg
    20881 cgtgatttgg ttggtcatgg tgttggccca actatgcacg aagaaccaat ggttcctaac
    20941 tatggtattg caggtcgtgg actccgtctt cgtgaaggaa tggtcttaac cattgaacca
    21001 atgatcaata caggcgattg ggaaattgat acagatatga aaactggttg ggcgcataag
    21061 accattgacg gtggattgtc atgtcagtat gaacaccaat ttgtcattac gaaagatgga
    21121 cctgttatct tgactagcca aggtgaagaa ggaacttatt aataaaaagt gaaaagacta
    21181 ctggaagttt attttgataa aaaatccagt agatcttttc ataataaaac gcattgtatc
    21241 aagtgttagg ggctgatatc atgcgttttt ctgcttttaa gattttttcc aactctgttt
    21301 gtaagcgcat cataacaaag ggtctaggat tcagggctct cctcctatat actattagta
    21361 aagtaaaact aagggaggat attttagtgt cgcagtctat tgttcctgta gagattccac
    21421 aatattgtcg ttttgattct aaaaagagaa atggaattct gtttaatgtt cgtattgcca
    21481 atcttaaatt tactttttta tattatactt cctgcgaaac aaaatatggt atagtagttc
    21541 tatgaatgat gaagcaagta aacaactaac tgatgcacga tttaagcgtc ttgttggtgt
    21601 tcagcgtacc acttttgaag agatgttagc tgtattaaaa acagcttatc aacttaaaca
    21661 cgcaaaaggt ggacgaaaac ctaaattaag cctagaagac cttcttatgc ccactcttca
    21721 atagtgcgag aatatcgaac ttatgaagaa attgcggctg attttggtat tcacgaaagc
    21781 aactttatcc gtcggagcca atgggttgaa ataactcttg ttcaaagtgg ttttacggtt
    21841 tcaagaactc ctctcagttc tgaggacacg gtaatgattg atgcgacgga agtaaaaatc
    21901 aatcgcccta aaaaaacaat tagcgaatga ttctggtaaa aagaaatttc acgctatgaa
    21961 ggctcaagcg attgtcacaa gtcaagggag aattgtttct ttggatatcg ctgtgaacta
    22021 tagtcatgat atgaagttgt tcaaaatgag tcgtagaaat atcgaacaag ctggtaaaat
    22081 cttggctgac agtggttatc aagggctcat gaagatatat cctcaagcac aaactccacg
    22141 taaatccagc aaactcaagc cgctaacagc tgaagataaa gcctataacc atgcgctatc
    22201 taaggaaaga agcaaggttg agaacatctt tgccaaagta aaaacgttta aaatattttc
    22261 aacaacctat cgaaatcatc gtaaacgctt cggattacga atgaatttga gtgctggtat
    22321 tatcaatcat gaactaggat tctagttttg caggaagtct attgaggtat tgagctagtt
    22381 tatgaaaaaa ttgggtgaaa agtcgagtgt tttagaaacc cacagtgtag tattctagtt
    22441 tcaatccact atattttgct actccccgta aagtttctat tttccctgat ttctgatata
    22501 atagaaatat tgacttcaag agtaaggaag agaagatgaa cgcattatta aatggaatga
    22561 atgaccgtca ggctgaggcg gtgcaaacga cagaaggtcc cttgctaatc atggcagggg
    22621 ctggttctgg aaagactcgt gttttgaccc accgtatcgc ttatttgatt gatgaaaagc
    22681 tggtcaatcc ttggaatatc ttggccatta cctttaccaa caaggctgcg cgtgagatga
    22741 aagagcgtgc ttatagcctc aatccagcga ctcaggactg tctgattgcg accttccact
    22801 ccatgtgtgt gcgtattttg cgtcgcgatg cggaccatat tggctacaat cgtaatttta
    22861 caattgtgga tcctggtgaa cagcgaacgc tcatgaaacg tattctcaaa cagttgaact
    22921 tggaccctaa aaaatggaat gaacgaacta ttttggggac catttccaat gctaagaatg
    22981 atttgattga tgatgttgct tatgctgccc aagctggcga tatgtatacg caaattgtgg
    23041 cccagtgtta tacagcctat caaaaagaac ttcgtcagtc tgaatccgtt gactttgatg
    23101 atttgattat gctgaccttg cgtctctttg atcaaaatcc tgatgttttg acctactacc
    23161 agcaaaaatt ccaatacatc cacgttgatg agtaccaaga taccaaccac gctcagtacc
    23221 aattggtcaa actcttggct tcccgtttta aaaatatctg tgtggttggg gatgcggacc
    23281 agtctatcta cggttggcgt ggtgctgata tgcagaatat cttggacttt gaaaaggatt
    23341 accccaaagc caaggttgtt ttgttggagg aaaattaccg ctcaaccaaa accattctcc
    23401 aagcggccaa cgaggttatt aaaaataata aaaatcgccg tcctaaaaat ctctggactc
    23461 aaaacgctga tggggagcaa atcgtttact atcgtgccga tgatgagctg gatgaggctg
    23521 tatttgtagc cagaaccatc gatgaactta gtcgcagtca aaacttcctt cataaggatt
    23581 ttgcagttct ctatcggact aatgcccagt cccgtacaat tgaggaagcc ctgctcaagt
    23641 ctaacattcc ttataccatg gttggcggaa ccaaattcta cagccgtaag gaaattcgcg
    23701 atattattgc ttatctcaac cttattgcta atttgagtga caatattagt tttgagcgta
    23761 ttatcaacga gcctaaacgt ggaattggtc taggtacagt tgagaaaatc cgtgattttg
    23821 caaatttgca aaatatgtct atgctggatg cttctgctaa tattatgttg tctggtatca
    23881 agggtaaggc agcccaatct atctgggatt ttgccaatat gatgcttgat ttgcgggagc
    23941 agctagacca cttaagcatt acagagttgg ttgagtccgt cctagaaaaa acaggttatg
    24001 tcgatattct taactcccaa gcgactctag aaagcaaggc acgggttgaa aatatcgaag
    24061 agtttctttc tgttacgaag aactttgatg acaccacgga tgtgacagaa gaggaaactg
    24121 gtctggacaa actgagtcgt ttcttaaatg acttggcttt gattgccgac acagattcag
    24181 gtagtcagga gacatcagaa gtgaccttga tgaccctgca tgctgccaaa ggtctcgaat
    24241 ttccagttgt ctttttgatt gggatggaag aaaatgtctt tccacttagt cgtgcgactg
    24301 aagattcaga tgaattagaa gaagagcgcc gtctagccta tgtaggtatc acgcgtgcag
    24361 agaaaattct ctatctgacc aatgccaact cacgcttgct ttttggtcgt accaattata
    24421 accgtccgac tcgttttatt aacgaaatca gttcagactt gcttgagtat caaggtctgg
    24481 ctcgtcctgc aaatacaagc tttaaggcat catatagcag tggtagtatt tcctttggtc
    24541 aaggtatgag tttggctcag gctcttcaag accgtaaacg cggtgctgcc ccaaaatcaa
    24601 tccagtcaag cggtcttcca tttggtcaat ttacagctgg cgcaaaacca gcatctagcg
    24661 aggcaaattg gtccattggt gatattgctc tccacaagaa atggggagag ggaaccgttc
    24721 tggaagtttc aggtagcggt gctaggcagg aattgaaaat caatttccca gaagtaggtt
    24781 tgaaaaaact tttagccagt gtggctccaa ttgagaaaaa aatctaattt tccatccttc
    24841 tcacgaataa taaagtgagg aggattttta tgtacagtat ttcattccaa gaagattcac
    24901 tattaccaag agaaaggctg gccaaggaag gagttgaagc gcttagtaac caagagttgc
    24961 tagctatttt actcaggaca ggaacacgtc aagctagcgt ttttgaaatt gcccaaaaag
    25021 tcttgaacaa tctttcaagc ctaacggatt tgaaaaaaat gaccctgcag gaattgcaga
    25081 gtttgtctgg tattgggcgt gttaaggcca tagaattaca agctatgatt gaactggggc
    25141 atcgtattca caaacacgag actcttgaaa tggaaagtat tctcagcagt caaaagttgg
    25201 ccaagaagat gcagcaggaa ttaggggata aaaaacaaga gcacctggtg gcactctatc
    25261 tcaatactca aaatcaaatc atccatcagc agaccatttt tatcgggtct gtaactcgta
    25321 gtatcgctga accgcgagag attcttcact atgcaatcaa gcatatggcg acttctctta
    25381 tcttggtcca caatcatcct tcaggagcgg tagcgcctag ccaaaatgat gatcatgtca
    25441 ctaaacttgt taaagaagcc tgcgaattga tggggattgt tctcttggac catttgattg
    25501 tctctcattc taattacttt agttatcgtg aaaagacaga tttaatctaa agttcattaa
    25561 cgacatagtc aaagagtttt ttatctttgg gacgattttc aaaaagaagt tctggatgcc
    25621 attggacacc gagaaaggcg acatcatccg tactcatgac agcctcaatg ataccatctt
    25681 taggatcatg agccacaact tttaaatttg gtgctaagtc cttgatgctc tggtggtgga
    25741 aggagttgat atgagagatt tctccataga tttcttggag aacggtatct ggttctgtta
    25801 ccaagcgttg agttgtgtac tcaacagaag aatcctgcca atggtcttcg atatcttggt
    25861 acaaagttcc acccatggca acgttaaaga gttgggtacc acggcagaca gagaaaatgg
    25921 gctttttctg tttaatagct tccttgatga gggccagttc gaagatatct ctttgaaggt
    25981 gatagtcatc actatcaatg gttttgggtt cgccataaaa ttttggatcg acattttgcc
    26041 cacctgtcaa gatgagcttg tcaatcaaac tgatatagtg gcaggccatt tcttgatcac
    26101 caatcggtag gatgatggga atccctccag catctttaac gccttcaaca aagccttttg
    26161 ctgcgtagct catcatgatg tcatcatctg gatgagtttt ttcgtttcct gtaatcccaa
    26221 taactggttt tttcataaaa tgattttcgc tttctaatcc tcttttcgca tgaagtagag
    26281 gagggtttgg agttcacttg tcaaatcgac atactgaacg accacgtctt ttggtaaatg
    26341 cagatggact ggtgaaaaac tgagaattcc tttcacacca gcatcaacca agagattagc
    26401 aacctcttgt gacttgacgc tgggaacagt taggatagca gtcttcacat cagcatcctt
    26461 gattttatcc ttgatctgag aaatcccgta aatgggaatc ccgtcaggag tttgggtacc
    26521 gacttcagga tggtcgtcta ggtcaaaggc catgataatc ttcatcttgt tacgttcgtg
    26581 gaagcggtag tggagaaggg catggcccat atttccaata ccaaccagca tgacattggt
    26641 aatagagttg tcattgagca aatcggcaaa aaatgtcatt agttttttga catcatagcc
    26701 aaaaccacga cgaccaagtt caccaaaata ggaaaaatca cgacgtacgg tcgctgaatc
    26761 aataccgata gcctctgcaa tttgcttaga gttggcacgt tcaatctttt ctgcatgaaa
    26821 tctcttaaaa attcgatagt agagagagag tctttttgct gtagcttttg gaatagcaaa
    26881 ctgtttatct ttcacaaaat cacaaccttt ctattcttct attttataga aacattgtga
    26941 aaaaatcaac aaaaataaga aaaaactaag aaaaatctta gttttgatgt aaaaaatctg
    27001 catgagatag aaaacggtag aggtctccga ccagcccctg ataaactttt ttgcccctaa
    27061 aagtcagaga agtcacataa agtgtatctg gtaaggttac acatcctgac aaagtcaaca
    27121 tgagagcctc atgatcctca tacttgagag tacgctctac atgatagcag tccttatagg
    27181 tcagttcaaa cattttggct ctatctttcc gattttgtaa agacaccacg ttctaccaag
    27241 ctatccatga ggaagtagaa tttttcctga tgaatatggt ggtcttctga tttgaaaata
    27301 tcaactagac gaaggccaaa cttgtcagtg atattgattt tagcccctgt aagttccttg
    27361 ttaatgatga ttttgagttg gaagccttca ccgctgtttg gcactttttc caaaaggcga
    27421 gtcagttcat agttaccaac cttagtttca aaaaaggtgt tatctttgag ggtgaatttt
    27481 ttaacagaag ggctaagagt gtaatcgtaa cgacaatttt ttaactgaat gattttttca
    27541 aatgccatat ggctaacctc cgataatttc ttttaaggtt tttgcgaggg tttgtaggtc
    27601 ttcaacggta ttttgtggcg acaaactgat gcgaagggat tccttcaagc gttctgaatt
    27661 tgcgccatac atggcttcaa gaacatggct ggattggaca acgcctgcag tacaggctga
    27721 gccagtagag attgaaattc cagctaaatc tagccgaagg agtaagaggt catttttctg
    27781 accaggaaat ccaatattga gaacataagg gagatgatgt tttcctctat tcaggtaata
    27841 ctgaatgccc tccagctctg ccagaaaggc agtttctaga ttttgtacat gttgaaaatg
    27901 ttcttcttgt ttttctaggt cttcttttag ggctgcaacc atgcctacaa tggcaggcag
    27961 attttcagtt cctgcacgtt ttttctgttc ctggtctccg ccatgtagat aggaatcaaa
    28021 gtccatgcta gatgcgtaga gaaaaccgat tcccttagga ccatggaatt tgtgggcaga
    28081 agcagtgaga aaatcaatgc ccaattcttc tgaatgaatt gggattttac caatagcctg
    28141 aactgcatca acatgatagg cagcagggtg ttgcttgagt atttggccaa tttcagcgat
    28201 gggcagtagg tttcctgtct cattattgac aaacatggta gaaaccaaaa tcgtatcgtc
    28261 acgtaaagcc ttttgaattt gctgggctgt gatttcttga ttttctggct ggataatggt
    28321 tgcttcaaac ccaaagtgtt gaaccaagta atcaattgtt tcaaggacag catggtgctc
    28381 gatggcagtt gtgatgatat gttttccttg ttcttggtga cgaagacagt agccaatgat
    28441 ggtagtatta ttgccttcag tcccaccaga agtgaaaaag atatgttgag gttttgtcct
    28501 tagtaactgg gctagttcct gacgggcttc tcgcaagagt ttgccagctt gacgaccatg
    28561 accatgaata ctagaaggat ttccgtgggt ttcttgcata accttggtca tagctgaaat
    28621 agcaactgct gacataggag tcgttgcagc attgtccaaa taaatcaaag aatcacctta
    28681 tttcttttta ttgtaggcaa agagtgggct gactggtttt ctttcgtgaa tacggacgat
    28741 agcatcacca attaactcac tagcagtgat gtagcataca tttttaggag ttttttcttt
    28801 tgttgctact gaatcagtca caagaatttc tttaatatta gtattgtcaa gaagctcagc
    28861 agctccctcg acgaagagac cgtggctaga aacagcataa atttctgtag ctccttcacg
    28921 ttcaacgatt ttagaagctt cagagaaggt acgtcctgta tttaaaatat catcaatcaa
    28981 gatagctttc ttaccttcaa catcaccaat aatataacct tcgttacgag ttgcatcgtc
    29041 ttgagggtag tcgataatgg cgataggagc atcaagatat tcagccaggc tacgcgcacg
    29101 tttgacacct gaatttttag ggctaacgac aacaacatct gaaccaagca atcctttatc
    29161 gcagtaatgt tttgcgaata ggggaacagt gaaaagatta tccactggaa tatcaaagaa
    29221 accttgaacc tgaacggcat gcaaatcaag agtcaggata cgatcaactc cagccttaac
    29281 cagcatattg gcaactagtt ttgctgtaag tggctcacga ggacaagcaa tgcggtcttg
    29341 acgtgcatag ccaaaatatg gaaggacaac gttgatactg tgggcacttg cacgcacaca
    29401 agcatcgacc atgattaaca attccattag gtggttgttg acagggaaac ttgttgattg
    29461 gatgatgtaa acatcataac cacggacact ttcttcgata tttacttgga tttctccgtc
    29521 tgaaaattga cgtgatgata gttttccaag tgggacacca acagcttggg caattttttg
    29581 tgcaatctct tggttagagt tgagtgcgaa aagtttcatg ttttttctat ctgacattat
    29641 agaccgtcct ctgtaaactt tataaatcct agttatattt accttacata tatgaactgg
    29701 gatttgtgta tttttatctt ttctatttta ccaaaaaatg gagattattt cagctatttt
    29761 tcatactttt gacaaatcga accaattttg aaggagcttt ttgataggaa atctgatttt
    29821 tctctaaaaa ttgtcgaaaa tcctgtttgc cttgctcatg attttccact tcaagctcca
    29881 attcgtaatc tgttatatca aagtatcggc tctgatccag tgccatgaga ccaatagctg
    29941 ttttcatttc atagcgaagc gttgttagac aaccaagaac ctgccagttc ttactttgga
    30001 taccatgttt cgccaattca tccagtacta gcccttgagg aagttcttcc ttactcagat
    30061 agttctcagc atcttttagt tgcaattttt ggttgtattc catgtttcca acactctgcg
    30121 ggactttgag tgtcaactca gcccagtctt caaaggttcg aatgcgcata gcgactttct
    30181 tttctcgcag ttcaaaatca ggcgtgtcga tgtagtaatt tgtttgaaga acaggagtga
    30241 cacctgtgaa ctggtctttt agacgattgt attcatcttt tttcaatagt gttttcaatt
    30301 caatttctaa atgtttcatt tttcttacct ttttttatcg ttgaaagcgg atttatggta
    30361 taataagcat tgtatttatt gtatatgaat ctggagaaaa aatcaaagat atttttgacg
    30421 gataatatga gaacaaggga gaatatatga ccttagaatg ggaagaattt ctagatcctt
    30481 acattcaagc tgttggtgag ttaaagatta aacttcgtgg tattcgtaag caatatcgta
    30541 agcaaaataa gcattctcca attgagtttg tgaccggtcg agtcaagcca attgagagca
    30601 tcaaagaaaa aatggctcgt cgtggcatta cttatgcgac cttggaacac gatttgcagg
    30661 atattgctgg cttacgtgtg atggttcagt ttgtagatga cgtcaaggaa gtagtggata
    30721 ttttgcacaa gcgtcaggat atgcgaatca tacaggagcg agattacatt actcatagaa
    30781 aagcatcagg ctatcgttcc tatcatgtgg tagtagaata tacggttgat accatcaatg
    30841 gagctaagac tattttggca gaaattcaaa ttcgtacttt ggccatgaat ttctgggcaa
    30901 cgatagaaca ttctctcaac tacaagtacc aaggggattt cccagatgag attaagaagc
    30961 gactggaaat tacagctaga atcgcccatc agttggatga agaaatgggt gaaattcgtg
    31021 atgatatcca agaagcccag gcactttttg atcctttgag tagaaaatta aatgacggtg
    31081 taggaaacag tgacgataca gatgaagaat acaggtaaac gaattgatct gatagccaat
    31141 agaaaaccgc agagtcaaag ggttttgtat gaattgcgag atcttttgaa gagaaatcag
    31201 tttatactca atgataccaa tccggatatt gtcatttcca ttggcgggga tggtatgctc
    31261 ttgtcggcct ttcataagta cgaaaatcag cttgacaagg tccgctttat cggtcttcat
    31321 actggacatt tgggcttcta tacagattat cgtgattttg agttggacaa gctagtgact
    31381 aatttgcagc tagatactgg ggcaagggtt tcttaccctg ttctgaatgt gaaggtcttt
    31441 cttgaaaatg gtgaagttaa gattttcaga gcactcaacg aagccagcat ccgcaggtct
    31501 gatcgaacca tggtggcaga tattgtaata aatggtgttc cctttgaacg ttttcgtgga
    31561 gacgggctaa cagtttcgac accgactggt agtactgcct ataacaagtc tcttggcggt
    31621 gctgttttac accctaccat tgaagctttg caattaacgg aaattgccag ccttaataat
    31681 cgtgtctatc gaacactggg ctcttccatt attgtgccta agaaggataa gattgaactt
    31741 attccaacaa gaaacgatta tcatactatt tcggttgaca atagcgttta ttctttccgt
    31801 aatattgagc gtattgagta tcaaatcgac catcataaga ttcactttgt cgcgactcct
    31861 agccatacca gtttctggaa ccgtgttaag gacgccttta tcggcgaggt ggatgaatga
    31921 ggtttgaatt tatcgcagat gaacatgtca aggttaagac cttcttaaaa aagcacgagg
    31981 tttctaaggg attgctggcc aagattaagt ttcgaggtgg agctattctg gtcaataatc
    32041 aaccgcaaaa tgcaacgtat ctattggacg ttggagacta cgttaccatt gacattcccg
    32101 ctgagaaagg ctttgaaacc ttggaggcta ttgagcttcc attagatatt ctctatgagg
    32161 atgaccactt tctagtcttg aataaaccct atggagtggc ttctattcct agtgtcaatc
    32221 actctaatac cattgccaat tttatcaagg gttactatgt caagcaaaat tatgaaaatc
    32281 agcaggttca cattgttacc agactagata gggatacttc tggcttgatg ctctttgcca
    32341 agcacggtta tgcccatgca cgattagaca agcagttgca gaagaaatct atcgagaaac
    32401 gctactttgc tttggttaag ggagatggac atttggagcc agaaggggaa attattgctc
    32461 cgattgcgcg tgatgaagat tccattatta ccagacgagt ggctaaaggc ggaaagtatg
    32521 cccatacttc atacaagatt gtagcttctt atggaaatat tcacttggtc tatattcacc
    32581 tgcacactgg tcgaacccat caaatccgag tccatttttc tcatatcggt tttcctttgc
    32641 tgggagatga tttgtatggt ggtagtctgg aagatggtat tcaacgtcag gctctgcatt
    32701 gccattacct atccttttat catccatttt tagagcaaga cttgcagtta gaaagtccct
    32761 tgccggatga tttcagtaac cttattaccc agttatcaac taatactcta taaaaactgt
    32821 ctcagagtat aattattatc ttaaaggaga aaactcatgg aagtttttga aagtctcaaa
    32881 gccaaccttg ttggtaaaaa tgctcgtatc gttctccctg aaggggaaga gcctcgtatt
    32941 cttcaagcaa caaaacgctt agtaaaagaa acagaagtga ttcctgtttt gcttggaaat
    33001 cctgaaaaaa ttaaaattta tcttgaaatt gaaggaatca tggatggtta tgaggtcatc
    33061 gaccctcaac attatcctca atttgaagaa atggtttctg ccttggtgga gcgtcgcaag
    33121 ggcaaaatga ctgaagaaga tgtacgcaag gttttggttg aagatgtcaa ctactttggt
    33181 gtgatgttgg tttacttggg cttggttgat ggaatggtgt caggagcgat tcactcaaca
    33241 gcttcaacag ttcgcccagc tctacaaatc atcaaaactc gtccaaatgt aactcgtact
    33301 tcaggagcct tcctcatggt tcgtggtacg gaacgttacc tatttggaga ctgtgccatt
    33361 aacatcaatc cagatgcaga agccttggct gaaattgcca tcaactcagc aatcacagct
    33421 aagatgtttg gcatcgaacc taaaattgcc atgttgagct attctactaa aggttcaggg
    33481 tttggtgaaa gcgttgataa ggtcgttgaa gcaactaaaa ttgctcacga cttgcgtcct
    33541 gaccttgaaa tcgatggtga gttgcaattt gatgcagcct ttgttcctga aactgcagct
    33601 ctgaaagctc ctggaagtac ggtagctggt caagcaaatg tcttcatctt cccaggtatc
    33661 gaggcaggaa atattggtta caagatggct gaacgcctgg gtggctttgc ggctgtagga
    33721 cctgttttgc aaggtttaaa caagccagtt aatgatcttt ctcgtggatg taatgcagat
    33781 gatgtttaca agttgaccct catcacagca gctcaagcag ttcatcaata gtgaaaacta
    33841 taaagtgata tactatgcta tactgtagtt atgaaactat gtacgaaaag cactgccatt
    33901 aattcctgag aactaaatta ctgattggtg tcaaaaagga aaacttccaa gcgatgatat
    33961 cctgtctata cacgacctat agaaatctgt aatatacata tccgtaaaac gataaattcc
    34021 ctttttgatt ttaaatgagt atgaaaagag aattttttgg ctctttgtca actgtagtgg
    34081 gttgaagaaa agctaagctc gagaaaggac aaatttc
//
LOCUS       DAVFER010000021        34008 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1105170250
            SAMEA2167659-rid19724873.denovo.021, whole genome shotgun sequence.
ACCESSION   DAVFER010000021 DAVFER010000000
VERSION     DAVFER010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2167659
            Sequence Read Archive: ERR388902
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 34008)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34008)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928716.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928716.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 04:07:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,118
            CDSs (total)                      :: 2,073
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 120
            CDSs (without protein)            :: 120
            Pseudo Genes (ambiguous residues) :: 0 of 120
            Pseudo Genes (frameshifted)       :: 67 of 120
            Pseudo Genes (incomplete)         :: 47 of 120
            Pseudo Genes (internal stop)      :: 34 of 120
            Pseudo Genes (multiple problems)  :: 23 of 120
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34008
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2167659-rid19724873.denovo.021"
                     /strain="1105170250"
                     /db_xref="taxon:1313"
     gene            complement(177..413)
                     /locus_tag="VU534_001082"
     CDS             complement(177..413)
                     /locus_tag="VU534_001082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU1513683.1"
                     /translation="MDVILSAIIFGISHLILSHRDPISLLYYSLIGFFFALVYRSTDN
                     LRLTILCHSFFNFLNHAKPIWIFVYNYIYYHFFR"
     gene            complement(426..899)
                     /locus_tag="VU534_001083"
     CDS             complement(426..899)
                     /locus_tag="VU534_001083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001246431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1513684.1"
                     /translation="MRNTKKLRQFGIFLLIILLSTYLPQTIGLYVTIILGLGADVYSL
                     ILTMGLVGSFLLLIWRLKKKKMLFIFEKKSWNWSFVFYLFATYVVYQILGNFWARYAH
                     LINHRNIHDEYFTVLFSNGQPTFLSTILSFVLPVIIGPVFEETLDRGYFMNTFFP"
     gene            complement(917..1102)
                     /gene="briC"
                     /locus_tag="VU534_001084"
     CDS             complement(917..1102)
                     /gene="briC"
                     /locus_tag="VU534_001084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biofilm-regulating peptide BriC"
                     /protein_id="HEU1513685.1"
                     /translation="MTGTNTFTVLSTEDLEQTSGGLAVWEDGYSRWLYYREFAPYMRQ
                     GALNSYIDAWKYGFRAG"
     gene            complement(1261..2028)
                     /locus_tag="VU534_001085"
     CDS             complement(1261..2028)
                     /locus_tag="VU534_001085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HEU1513686.1"
                     /translation="MNIAKIVREAREQSRLTTLDFATGIFDEFIQLHGDRSFRDDGAV
                     VGGIGWLGDQAVTVVGIQKGKSLQDNLKRNFGQPHPEGYRKALRLMKQAEKFGRPVVT
                     FINTAGAYPGVGAEERGQGEAIARNLMEMSDLKVPIIAIIIGEGGSGGALALAVADRV
                     WMLENSIYAILSPEGFASILWKDGTRAMEAAELMKITSHELLEMDVVDKVISEIGLSS
                     KELIKSVKKELQTELARLSQKPLEELLEERYQRFRKY"
     gene            complement(2025..2891)
                     /locus_tag="VU534_001086"
     CDS             complement(2025..2891)
                     /locus_tag="VU534_001086"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001173351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit beta"
                     /protein_id="HEU1513687.1"
                     /translation="MALFSKKDKYIRINPNRSVREKPQAKPEVPDELFSQCPGCKHTI
                     YQKDLGSERICPHCSYTFRISAQERLALTIDMGTFKELFTGIESKDPLHFPGYQKKLA
                     SMREKTGLHEAVVTGTALIKGQTVALGIMDSNFIMASMGTVVGEKITRLFEYATVEKL
                     PVVLFTASGGARMQEGIMSLMQMAKISAAVKRHSNAGLFYLTILTDPTTGGVTASFAM
                     EGDIILAEPQSLVGFAGRRVIENTVRESLPEDFQKAEFLLEHGFVDAIVKRRDLPDTI
                     ASLVRLHGGSPR"
     gene            complement(2928..4295)
                     /gene="accC"
                     /locus_tag="VU534_001087"
     CDS             complement(2928..4295)
                     /gene="accC"
                     /locus_tag="VU534_001087"
                     /EC_number="6.3.4.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000488661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HEU1513688.1"
                     /translation="MFRKILIANRGEIAVRIIRAARELGIATVAVYSTADKEALHTLL
                     ADEAVCIGPGKATESYLNINAVLSAAVLTEAEAIHPGFGFLSENSKFATMCEEVGIKF
                     IGPSGHVMDMMGDKINARAQMIKAGVPVIPGSDGEVHNSEEALIVAEKIGYPVMLKAS
                     AGGGGKGIRKVEKPDDLVSAFETASSEAKANYGNGAMYIERVIYPARHIEVQILGDEH
                     GHVIHLGERDCSLQRNNQKVLEESPSIAIGKTLRHEIGAAAVRAAEFVGYENAGTIEF
                     LLDEASSNFYFMEMNTRVQVEHPVTEFVSGVDIVKEQICIAAGQPLSVKQEDIVLRGH
                     AIECRINAENPAFNFAPSPGKITNLYLPSGGVGLRVDSAVYPGYTIPPYYDSMIAKII
                     VHGENRFDALMKMQRALYELEIEGVQTNADFQLDLISDRNVIAGDYDTSFLMETFLPK
                     YQEKE"
     gene            complement(4307..4729)
                     /gene="fabZ"
                     /locus_tag="VU534_001088"
     CDS             complement(4307..4729)
                     /gene="fabZ"
                     /locus_tag="VU534_001088"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HEU1513689.1"
                     /translation="MIDIQGIKEALPHRYPMLLVDRVLEVSEDTIVAIKNVTINEPFF
                     NGHFPQYPVMPGVVIMEALAQTAGVLELSKPENKGKLVFYAGMDKVKFKKQVVPGDQL
                     VMTATFVKRRGTIAVVEAKAEVDGKLAASGTLTFAIGN"
     gene            complement(4726..5211)
                     /locus_tag="VU534_001089"
     CDS             complement(4726..5211)
                     /locus_tag="VU534_001089"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001052236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HEU1513690.1"
                     /translation="MNLNDIKDLMTQFDQSSLREFSYKNGTDELQFSKNEARPVPEVA
                     TQVAPAPVLATPSPVAPTSAPAETVAEEVPAPAEASVATEGNLVESPLVGVVYLAAGP
                     DKPAFVTVGDSVKKGQTLVIIEAMKVMNEIPAPKDGVVTEILVSNEEMVEFGKGLVRI
                     K"
     gene            complement(5214..6449)
                     /gene="fabF"
                     /locus_tag="VU534_001090"
     CDS             complement(5214..6449)
                     /gene="fabF"
                     /locus_tag="VU534_001090"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000774039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HEU1513691.1"
                     /translation="MKLNRVVVTGYGVTSPIGNTPEEFWNSLATGKIGIGGITKFDHS
                     DFDVHNAAEIQDFPFDKYFVKKDTNRFDNYSLYALYAAQEAVNHANLDVEALNRDRFG
                     VIVASGIGGIKEIEDQVLRLHEKGPKRVKPMTLPKALPNMASGNVAMRFGANGVCKSI
                     NTACSSSNDAIGDAFRSIKFGFQDVMLVGGTEASITPFAIAGFQALTALSTTEDPTRA
                     SIPFDKDRNGFVMGEGSGMLVLESLEHAEKRGATILAEVVGYGNTCDAYHMTSPHPEG
                     QGAIKAIKLALEEAEISPEQVAYVNAHGTSTPANEKGESGAIVAVLGKEVPVSSTKSF
                     TGHLLGAAGAVEAIVTIEAMRHNFVPMTAGTSEVSDYIEANVVYGQGLEKEIPYAISN
                     TFGFGGHNAVLAFKRWENR"
     gene            complement(6471..7202)
                     /gene="fabG"
                     /locus_tag="VU534_001091"
     CDS             complement(6471..7202)
                     /gene="fabG"
                     /locus_tag="VU534_001091"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HEU1513692.1"
                     /translation="MKLEHKNIFITGSSRGIGLAIAHKFAQAGANIVLNSRGAISEEL
                     LAEFSNYGIKVVPISGDVSDFADAKRMIDQAIAELGSVDVLVNNAGITQDTLMLKMTE
                     ADFEKVLKVNLTGAFNMTQSVLKPMMKAREGAIINMSSVVGLMGNIGQANYAASKAGL
                     IGFTKSVAREVASRNIRVNVIAPGMIESDMTAILSDKIKEATLAQIPMKEFGQAEQVA
                     DLTVFLAGQDYLTGQVVAIDGGLSM"
     gene            complement(7236..8156)
                     /gene="fabD"
                     /locus_tag="VU534_001092"
     CDS             complement(7236..8156)
                     /gene="fabD"
                     /locus_tag="VU534_001092"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HEU1513693.1"
                     /translation="MTKTAFLFAGQGAQYLGMGRDFYDQYPIVKETIDRASQVLGYDL
                     RYLIDTEEDKLNQTRYTQPAILATSVAIYRLLQEKGYQPDMVAGLSLGEYSALVASGA
                     LDFEDAVALVAKRGAYMEEAAPADSGKMVAVLNTPVEVIEEACQKASELGVVTPANYN
                     TPAQIVIAGEVVAVDRAVELLQEAGAKRLIPLKVSGPFHTALLEPASQKLAETLAQVS
                     FSDFTCPLVGNTEAAVMQKEDIAQLLTRQVKEPVRFYESIGVMQEAGISNFIEIGPGK
                     VLSGFVKKIDQTAHLAHVEDQASLVALLEK"
     gene            complement(8149..9123)
                     /gene="fabK"
                     /locus_tag="VU534_001093"
     CDS             complement(8149..9123)
                     /gene="fabK"
                     /locus_tag="VU534_001093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000857459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-[acyl-carrier-protein] reductase FabK"
                     /protein_id="HEU1513694.1"
                     /translation="MKTRITELLKIDYPIFQGGMAWVADGDLAGAVSKAGGLGIIGGG
                     NAPKEVVKANIDKIKSLTDKPFGVNIMLLSPFVEDIVDLVIEEGVKVVTTGAGNPSKY
                     MERFHEAGIIVIPVVPSVALAKRMEKIGADAVIAEGMEAGGHIGKLTTMTLVRQVATA
                     ISIPVIAAGGIADGEGAAAGFMLGAEAVQVGTRFVVAKESNAHPNYKEKILKARDIDT
                     TISAQHFGHAVRAIKNQLTRDFELAEKDAFKQEDPDLEIFEQMGAGALAKAVVHGDVD
                     GGSVMAGQIAGLVSKEETAEEILKDLYYGAAKKIQEEASRWTGVVRND"
     gene            complement(9242..9466)
                     /locus_tag="VU534_001094"
     CDS             complement(9242..9466)
                     /locus_tag="VU534_001094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000257841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HEU1513695.1"
                     /translation="MAVFEKVQEIIVEELGKDASEVTLESTFDDLDADSLDLFQVISE
                     IEDAFDIQIEAENDLKTVGDLVAYVEEQAK"
     gene            complement(9526..10500)
                     /locus_tag="VU534_001095"
     CDS             complement(9526..10500)
                     /locus_tag="VU534_001095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III"
                     /protein_id="HEU1513696.1"
                     /translation="MAFAKISQVAHYVPEQVVTNHDLAQIMDTNDEWISSRTGIRQRH
                     ISRTESTSDLATEVAKKLMAKAGITGEELDFIILATITPDSMMPSTAARVQANIGANK
                     AFAFDLTAACSGFVFALSTAEKFIASGRFQKGLVIGSETLSKAVDWSDRSTAVLFGDG
                     AGGVLLEASEQEHFLAESLNSDGSRSECLTYGHSGLHSPFSDQESADSFLKMDGRTVF
                     DFAIRDVAKSIKQTIDESPIEVTDLDYLLLHQANDRILDKMARKIGVDRAKLPANMME
                     YGNTSAASIPILLSECVEQGLIPLDGSQTVLLSGFGGGLTWGTLILTI"
     gene            complement(10500..10934)
                     /locus_tag="VU534_001096"
     CDS             complement(10500..10934)
                     /locus_tag="VU534_001096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEU1513697.1"
                     /translation="MDYQRINEYLTSIFNNVLVIEEVNLRGSRFKDISIKEMHTIDVI
                     GKAPDVTPSQVSKELMVTLGTVTTSLNNLERKGYIERVRSEQDRRVVHLHLTKKGRLI
                     HRLHKRFHKAMVEKIIDGMSEEEIAVMGKGLTNLYQFLEDLK"
     gene            complement(11028..11813)
                     /locus_tag="VU534_001097"
     CDS             complement(11028..11813)
                     /locus_tag="VU534_001097"
                     /EC_number="4.2.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase"
                     /protein_id="HEU1513698.1"
                     /translation="MEHIIYQLEEDLAILTLNRPEVANGFHIPMCEEILEALTLAEEN
                     PAVHFILINANGKVFSVGGDLVEMKRAVDEDDIPSLTKIAELVNTISYKIKQIAKPVL
                     MEVDGAVAGAAANMAVAADFCLATDKAKFIQAFVGVGLAPDAGGIHLLSRSIGVTRAA
                     QLAMTGEALTAEKALEWGLVYRVSEAEKLEKTREQLLKKLRRASSNSYAAIKKLVWES
                     QFKDWQGYATLELNLQKSLAQTEDFKEGVRAHSERRRPKFTGK"
     gene            12138..13502
                     /locus_tag="VU534_001098"
     CDS             12138..13502
                     /locus_tag="VU534_001098"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HEU1513699.1"
                     /translation="MKVVKFGGSSLASASQLEKVLNIVKSDSERRFVVVSAPGKRNAE
                     DTKVTDALIKYYRDYVAGNDISKNQSWIIDRYAAMVSELGLKPAVLEKISKSIHALAT
                     LPIEENEFLYDTFLAAGENNNAKLIAAYFNQNGIDARYMHPREAGIVVTSEPGHARII
                     PSSYDKIEELTNTNEVLVIPGFFGVTKENQICTFSRGGSDITGSIIAAGVKADLYENF
                     TDVDGIFAAHPGIIHQPHSIPELTYREMRELAYAGFSVLHDEALLPAYRGKIPLVIKN
                     TNNPDHPGTRIVLKHSNDEFPVVGIAGDSGFVSINMSKYLMNREVGFGRKVLQILEEL
                     NIGWEHMPTGIDNLSIILRSRQLTPIKEEEILRQLVQKAKVDHAEIEHDLSIIMIVGE
                     KMKSHIGVTATATRALSENKINIQMMSQGSSEVSIMFVVNKDQEKAAIKALYNAFFGE
                     SKED"
     gene            13505..13876
                     /locus_tag="VU534_001099"
     CDS             13505..13876
                     /locus_tag="VU534_001099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000079352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF956 family protein"
                     /protein_id="HEU1513700.1"
                     /translation="MAQSLNKTVLLSTTGTSYLSIAGKVGKFLVGDQALEFYPDVNVE
                     QFIQIPWSHINQIGANVTGRKISRHFEVFTDKGKFLFASKDSGAILKIAREKLGNDKV
                     VKLPTLIQTISQKFKNLFAKK"
     gene            14089..15363
                     /gene="serS"
                     /locus_tag="VU534_001100"
     CDS             14089..15363
                     /gene="serS"
                     /locus_tag="VU534_001100"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000884256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HEU1513701.1"
                     /translation="MLDIKRIRTDFEAVAEKLATRGVDAAVLNEMKEIDAKRRNILVK
                     VETLKAERNTVSAEIAQAKRNKENTDDKIAAMQNLSAEVKALDAELAEIDAKLTEFTT
                     TLPNIPADSVPVGADEDDNVEVRRWGTPREFDFEPKAHWDLGEDLGILDWERGGKVTG
                     ARFLFYKGLGARLERAIYNFMLDEHGKEGYTEVITPYIVNHDSMFGTGQYPKFKEDTF
                     ELSDTNFVLIPTAEVPLTNYYRDEILDGKDLPIYFTAMSPSFRSEAGSAGRDTRGLIR
                     LHQFHKVEMVKFAKPEESYEELEKMTANAENILQKLNLPYRVVALSTGDMGFSAAKTY
                     DLEVWIPAQNNYREISSCSNTEDFQARRAQIRYRDEADGKVKLLHTLNGSGLAVGRTV
                     AAILENYQNEDGSVTIPEALRPYMGGAEVIKP"
     gene            complement(15388..16287)
                     /locus_tag="VU534_001101"
     CDS             complement(15388..16287)
                     /locus_tag="VU534_001101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000735961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HEU1513702.1"
                     /translation="MKKLPLVFSGCLLGLAGAGNLILDTLPVLSHLFSLIGLVLWIYF
                     LILHLFNWKETKQELTKPPLLSGMATFPMAGMILSTYVFRVFSYLPLVAQGIWWFSFL
                     LDLTLIAGFTIKFACPGRRVHATPSWTVLYVGIAVAALTYPLVGIIEIAYATLSFGFL
                     LTFYLYPLIYSDLKKHPLPLALLGQEGIYCAPFSLLLASLVRVGGTSLPTWVLIVMIL
                     ASQSFFFFVLTRLPNILKQGFQPAFSALTFPTIITATSLKMAQGILKLPFLDYLVLAE
                     TIICLTILFFVLGAYLIWLRKKV"
     gene            complement(16397..16945)
                     /locus_tag="VU534_001102"
     CDS             complement(16397..16945)
                     /locus_tag="VU534_001102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000206764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HEU1513703.1"
                     /translation="MTTFTIHTVESAPAEVKEILETVEKDNNGYIPNLIGLLANAPTV
                     LEAYQIVSSIHRRNSLTPVEREVVQITAAVTNGCAFCVAGHTAFSIKQIQMNDDLIQA
                     LRNRTPIETDPKLDTLAKFTLAVINTKGRVGDEALSEFLEAGYTQQNALDVVFGVSLA
                     ILCNYANNLANTPINPELQPYA"
     gene            complement(17163..18485)
                     /locus_tag="VU534_001103"
     CDS             complement(17163..18485)
                     /locus_tag="VU534_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:alanine symporter family protein"
                     /protein_id="HEU1513704.1"
                     /translation="MLELLKSIDAFAWGPPLLILLVGTGIYLTIRLGLLQVLRLPKAF
                     QLIFIQDKGHGDVSSFAALCTALASTVGTGNIIGVATAIKVGGPGALFWMWMAAFFGM
                     ATKYAEGLLAIKYRTKDDHGAVAGGPMHYILLGMGEKWRPLAVLFAVAGVLVALLGIG
                     TFTQVNSIAESIQNTTTISPAITALVLSVFVAIAVFGGLKSISKVSTTVVPFMAIIYI
                     LGTLTVIFFNIGKIPGTIALVFTSAFSPLAAVGGFAGASVRMAIQNGVARGVFSNESG
                     LGSAPIAAAAAKTNEPVEQGLISMTGTFIDTLIICTLTGLTILVTGVWSGDLNGVALT
                     QSAFSTNFSHFGPALLTIFLVLFAFTTILGWNYYGERCFEFLFGVRFIWLYRVVFVLM
                     VLLGGFIELDMVWIIADIVNALMALPNLIALLVLSPVVIAETKKYFDK"
     regulatory      complement(18576..18664)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            complement(18828..21164)
                     /locus_tag="VU534_001104"
     CDS             complement(18828..21164)
                     /locus_tag="VU534_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HEU1513705.1"
                     /translation="MNKKILETLEFDKVKALFEPHLLTEQGLEQLRQLAPTAKADKIK
                     QAFAEMKEMQALFVEQPHFTILSTKEIAGVCKRLEMGADLNIEEFLLLKRVLLASREL
                     QNFYTNLENVSLEELALWFEKLHDFPQLQGNLQAFNDAGFIENFASEELARIRRKIHD
                     SESQVRDVLQDLLKQKAQLLTEGIVASRNGRQVLPVKNTYRNKIAGVVHDISASGNTV
                     YIEPREVVKLSEEIASLRADERYEMLRILQEISERVRPHAAEIANDAWIIGHLDLIRA
                     KVRFIQERQAVVPQLSENQEIQLLHVCHPLVKNAVANDVYFGQDLTAIVITGPNTGGK
                     TIMLKTLGLTQVMAQSGLPILADKGSRVGIFEEIFADIGDEQSIEQSLSTFSSHMTNI
                     VDILGKVNQHSLLLLDELGAGTDPQEGAALAMAILEDLRLRQIKTMATTHYPELKAYG
                     IETAFVQNASMEFDTATLRPTYRFMQGVPGRSNAFEIAKRLGLSEVIVGDASQQIDQD
                     NDVNRIIEQLEEQTLESRKRLDNIREVEQENLKMNRALKKLYNELNREKETELNKARE
                     QAAEIVDMALSESDQILKNLHSKSQLKPHEIIEAKAKLKKLAPEKVDLSKNKVLQKAK
                     KKRAPKVGDDIVVLSYGQRGTLTSQLKDGRWEAQVGLIKMTLEEKEFDLVQAQQEKPV
                     KKKQVNVVKRTSGRGPQARLDLRGKRYEEAMNELDTFIDQALLNNMAQVDIIHGIGTG
                     VIREGVTKYLQRNKHVKSFGYAPQNAGGSGATIVTFKG"
     gene            complement(21268..21816)
                     /locus_tag="VU534_001105"
     CDS             complement(21268..21816)
                     /locus_tag="VU534_001105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000622948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
                     /protein_id="HEU1513706.1"
                     /translation="MISFLLLLVLVWGFYIGYRRGLLLQVYYLISAMASAFMAGQFYK
                     GLGEQFHLLLPYANSQEGQGTFFFPSDQLFQLDKVFYAGIGYLLVFGIVYSIGRLLGL
                     LLHLIPSKKLGGKLFQVSAGILSMLVTLFVLQMALTILATIPMAVIQNPLEKSIVAKH
                     IIQSIPVTTSWLKQIWVTNLIG"
     gene            complement(21813..22115)
                     /gene="zapA"
                     /locus_tag="VU534_001106"
     CDS             complement(21813..22115)
                     /gene="zapA"
                     /locus_tag="VU534_001106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HEU1513707.1"
                     /translation="MANLNRFKFTFGKKSLTLTSEHDNLFMEEIAKVATEKYQAIKEQ
                     MPSADDETIALLLAVNCLSTQLSREIEFDDKEQELEELRHKLVTCKQEQSKIEDSL"
     gene            22202..23083
                     /locus_tag="VU534_001107"
     CDS             22202..23083
                     /locus_tag="VU534_001107"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000146880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HEU1513708.1"
                     /translation="MASITLTPSEKDIQAFLEHYQTSLAPSKNPYIRYFLKLPQATVS
                     IYTSGKILLQGEGAEKYASFFGYQAVEQTSGQNLPLIGTDEVGNGSYFGGLAVVAAFV
                     TPDQHDFLRKLGVGDSKTLTDQKIRQITPILKEKIQHQALLLSPSKYNEVIGDRYNAV
                     SVKVALHNQAIYLLLQKGVQPEKIVIDAFTSAKNYDKYLAQEANRFSNPISLEEKAEG
                     KYLSVAVSSVIARDLFLENLENLGRELGYQLPSGAGTASDKVASQILQAYGMQGLSFC
                     AKLHFKNTEKAKKRLER"
     gene            23087..23701
                     /gene="lepB"
                     /locus_tag="VU534_001108"
     CDS             23087..23701
                     /gene="lepB"
                     /locus_tag="VU534_001108"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001048155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HEU1513709.1"
                     /translation="MNSFKNFLKEWGLFLLILSLLALSRIFFWSNVRVEGHSMDPTLA
                     DGEILFVVKHLPIDRFDIVVAHEEDGNKDIVKRVIGMPGDTIRYENDKLYINDKETDE
                     PYLADYIKRFKDDKLQSTYSGKGFEGNKGTFFRSIAQKAQAFTVDVNYNTNFSFTVPE
                     GEYLLLGDDRLVSSDSRHVGTFKAKDITGEAKFRLWPITRIGTF"
     gene            23980..26346
                     /locus_tag="VU534_001109"
     CDS             23980..26346
                     /locus_tag="VU534_001109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000454449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HEU1513710.1"
                     /translation="MEVYFSGTIERIIFENPSNFYRILLLEIDDTDAEDFDDFEIIVT
                     GTMADVIEGEDYTFWGQIVQHSKYGEQLQISRYDRAKPTSKGLVKYFSSSHFKGIGLK
                     TAQKIVDTYGENTIDEILQHPEKLEGIAGLSAKNREAFVSTLRLNYGTEMILAKLANY
                     GIPNKLAFQIQDFYKEETLDVVENYPYQLVEDIKGLGFTIADQLAEELGIESQAPERF
                     RAGLVHSLFQACMETGDTYVEARDLLEQTLTLLESSRPVELDPSQVAQELSYLIEEDK
                     VQQIDTKIFDNSLFFAEEGIRSHLVRILEKGKQKSHDLETIQKHITTVEQELGIEYDN
                     IQKQAICDAIQNKVFILTGGPGTGKTTVINGIIAVYALLEGLDFRKKSNLPILLAAPT
                     GRAARRMNELTGLPSATIHRHLGMTGDDDTSHLEDYLDADFIIVDEFSMVDTWLANQL
                     FSNISSNSKILIVGDSDQLPSVSPGQVLADLLHIPLIPQTRLEKIYRQSKESTIVTLA
                     SQIRQGILPADFTQKKADRSYFEIASGHIPATIEKILGAALRNGIPARDIQVLAPMYR
                     GTAGIDAINQLMQDLLNPPQKDQLSFEAPQCHYRKRDRVIHLVNDAEINVFNGDLGAI
                     TDLIPGKYTESKQDEIVIDFDGNEVSYPRNEWYKIRLAYAMSIHKSQGSEFPVVILPI
                     TSASRRMLERNLIYTAITRAKSKLILLGELQAFDYATQHIGTARKTYLIERFSDLLEN
                     VEEKQQAVSETVTSSASEQSYILTEENWDRIPAMIGITDTDLKEIFGK"
     gene            complement(26394..27677)
                     /locus_tag="VU534_001110"
     CDS             complement(26394..27677)
                     /locus_tag="VU534_001110"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HEU1513711.1"
                     /translation="MSVSFENKETNRGVLTFTISQDQIKPELDRVFKSVKKSLNVPGF
                     RKGHLPRPIFDQKFGEEALYQDAMNALLPNAYEAAVKEAGLEVVAQPKIDVTSMEKGQ
                     DWVITAEVVTKPEVKLGDYKNLEVSVDVEKEVTDADVEERIERERNNLAELVIKEAAA
                     ENGDTVVIDFVGSIDGVEFDGGKGENFSLGLGSGQFIPGFEDQLVGHSAGETVDVIVT
                     FPEDYQAEDLAGKEAKFVTTIHEVKAKEVPALDDELAKDIDEEVETLADLKEKYSKEL
                     AAAKEEAYKDAVEGAAIDTAVENAEIVELPEEMIHEEVHRSVNEFLGNLQRQGINPDM
                     YFQITGTTQEDLHNQYQAEAESRTKTNLVIEAVAKAEGFDASEEEIQKEVEQLAADYN
                     MEVAQVQNLLSADMLKHDITIKKAVELITSTATVK"
     gene            complement(28463..29599)
                     /locus_tag="VU534_001111"
     CDS             complement(28463..29599)
                     /locus_tag="VU534_001111"
                     /EC_number="1.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000682970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HEU1513712.1"
                     /translation="MKHSVHFGAGNIGRGFIGEILFKNGFHIDFVDVNNQIIHALNEK
                     GKYEIEIAQKGQSRIEVTNVAGINSKEHPEQVIEAIQKTDIITTAIGPNILPFIAELL
                     AKGIEARRVAGNTQALDVMACENMIGGSQFLYQEVKKYLSPEGLTFADNYIGFPNAAV
                     DRIVPAQSHEDSLFVVVEPFNEWVVETKRLKNPDLRLKDVHYEEDLEPFIERKLFSVN
                     SGHATSAYIGAHYGAKTILEALQNPNIKSRIESVLAEIRSLLIAKWNFDKKELENYHK
                     VIIERLENPFIVDEVSRVARTPIRKLGYNERFIRPIRELKELSLSYKNLLKTVGYVFD
                     YRDVNDEESIRLGELLAKQSVKDVVIQVTGLDDQELIEQIVEYI"
     gene            complement(29661..30098)
                     /locus_tag="VU534_001112"
     CDS             complement(29661..30098)
                     /locus_tag="VU534_001112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEU1513713.1"
                     /translation="MKLEKHLIKLNKQFSNKEEAICYCGQVLYEGGYVNEDYIEAMIE
                     RDKELSVYMGNFIAIPHGTDAAKNDVLKSGITVVQVPRGVDFGNVSNPQVATVLFGIA
                     GIGNEHLEIIQKISIFCADVDNVLKLADAQSKEEVLRLFDAVE"
     gene            complement(30100..32055)
                     /locus_tag="VU534_001113"
     CDS             complement(30100..32055)
                     /locus_tag="VU534_001113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HEU1513714.1"
                     /translation="MLLTKREEQLLKAFLHVGKLSMQDMTEILQVSSRTIYRTLSDLT
                     DSMEQYGIEITKHGKYYILTGELDDLPTELEVLVEYSPQERQELITYRLLTESGFVTN
                     EALQECTKVSNVTIIQDISDIDKRLLDFDLKIERQKGYRISGDSVGKRRFLAILLTNC
                     ISVADFSTGNFGSFDILEADRTGLASQIVNKQLSGFPDMDARMKMFFAILLSLIGQEQ
                     NIENSPNTSKQALEISQKIFQAYSKQTAQFYSIQEIIYFASILDELIIKRQDNPLFTE
                     KFDGEFFYNISNLIDTVSMYTKIDFFKDKVLFNFLFHHIRFSLGVPILFQGENLPESI
                     QILVERNKFLYTVISLLVNDIFPKYLHTEYEYGMIALHFISSLGRSPEIYPVRVLLLT
                     DERRVTRDLLVSKIKSVAPFVELIDIQSLVDYHSIDLSQYDYILSTKPLTNQEIDVIS
                     SFPTVKELLELQERLQYVQAHRTIVARDAIAPEKSYDLQDYLISSSQLLSQFELVQLE
                     NNQSFEHTVEQIIQYQKNVSDRAYLTRKLLSHFQNSPMAIPNTGLVLLHSQSSKVTTN
                     SFTMFELKLPISALSMKREEEEVKRCLLMLMSKEASEEARDLMTAISQSIIENHLYTE
                     IYKTGNQSIIYQMLNTIFNEKIKKLEN"
     gene            complement(32079..33848)
                     /locus_tag="VU534_001114"
     CDS             complement(32079..33848)
                     /locus_tag="VU534_001114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000391672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol transporter subunit IICBA"
                     /protein_id="HEU1513715.1"
                     /translation="MEEKVSLKVRVQKLGTSLSNMVMPNIGAFIAWGVLTALFIADGY
                     LPNEQLATVVGPMLTYLLPILIGYTGGYMIHGQRGAVVGAIATVGAITGSSVPMFIGA
                     MVMGPLGGWTIKKFDEKFQEKIRPGFEMLVNNFSAGLVGFALLLLAFYAIGPVVSTLT
                     GAVGNGVEAIVNARLLPMANIIIEPAKVLFLNNALNHGIFTPLGVEQVAQAGKSILFL
                     LEANPGPGLGILLAYAVFGKGSAKSSSWGAMVIHFFGGIHEIYFPYVMMKPTLFLAAM
                     AGGISGTFTFQLLDAGLKSPASPGSIIAIIATAPKGVWPHLNVLLGVLVAAVVSFLVA
                     ALILHADKSTEDSLEAAQAATQAAKAQSKGQLVSTSVDAVVSTDSVEKIIFACDAGMG
                     SSAMGASILRDKVKKAGLEIPVSNQAISNLLDTPKTLIVTQEELTPRAKDKSPSAIHV
                     SVDNFLASSRYDEIVASLTGASPIAEIEGDIPTSAPVDSQESDLNHIDAVVVAYGKAQ
                     GTATMGCETIRAIFRNKNIRIPVSTAKISELGEFNSKNIMIVTTISLQAEVQQAAPNS
                     QFLIVDSLVTTPEYDKMAARMYK"
BASE COUNT        10106 a         7622 c         6418 g         9862 t
ORIGIN      
        1 tctttctaat gagttgtttt gtcgcttttc attataggtc atatgggact ttttttctac
       61 aataaaatag gctccataat atctataggg gatttaccca ctacaaatat tatagagcca
      121 acaataaaaa gaaaaagtgt ttgatagata tcaaacactt ttttctttgc ctcccactat
      181 ctaaaaaaat gataatagat ataattgtaa acaaaaatcc agataggttt tgcatgattg
      241 agaaagttaa aaaaactatg gcagagaatc gttaatctca gattgtcggt agaacgataa
      301 acaagggcaa aaaagaaacc aatcagacta taatataata aactaattgg atctctgtga
      361 gatagtatca aatggctaat cccaaagatg atagcagata ggataacatc caaatagtac
      421 ttggactagg gaaagaaggt attcataaaa taccctctat caagagtctc ctcaaaaaca
      481 ggaccgatga ttacaggcag gacaaaagat aagatagtcg ataaaaaggt tggttgtcca
      541 tttgaaaaaa gcacggtaaa atactcatca tgaatattcc tatgattaat caaatgagca
      601 tagcgtgccc aaaaattacc gagaatctga taaaccacat aagttgcaaa taagtagaag
      661 acaaatgacc agttccagct ctttttctca aagataaaga gcatcttttt cttttttaac
      721 ctccaaatta atagaaggaa acttcccact aatcccattg ttaaaataag agaatagaca
      781 tcagctccta accctaaaat gatcgtcaca tacaatccaa ttgtttgtgg taaataggta
      841 gatagtaaaa taataagcaa aaatattcca aattgtctta gtttttttgt gtttctcatc
      901 gtactttttt gaaagattac cctgctcgga agccgtactt ccaagcatct atataagaat
      961 taagtgcccc ttgcctcata tagggagcaa attctctata atataaccat ctactatatc
     1021 catcttccca aacagcaaga ccacctgaag tttgctccaa gtcctcagtt gaaagaactg
     1081 taaatgtatt tgtacctgtc attgcaagta ccttcttaaa atagattgtt gtaggctcac
     1141 atttatagta tatttctttt tttgtctatt ttatagccca tctcctcaac tggcaatttt
     1201 tcgacctgaa ttacattttt ccataaaaaa tgagaccttt ctagtctcat ttagtcattc
     1261 ttagtatttt ctaaatcgtt gatagcgttc ttccagcaac tcttctagcg gtttttgtga
     1321 aagtctagcc agctccgttt ggagttcttt tttgacactc ttaatcagtt ctttactaga
     1381 aagtcctatt tcagaaatca ccttatccac cacgtccatt tctaacagtt catgcgaagt
     1441 gattttcatc agttctgctg cttccatagc gcgagtaccg tccttccata aaatggaagc
     1501 aaagccttct ggactgagaa tggcatagat agaattttcc agcatccaga cacggtccgc
     1561 gacagctaga gccagagccc cgcctgaacc accttcaccg ataataatgg cgataatagg
     1621 aactttcagg tcactcattt ccatgagatt gcgagcgata gcttcccctt gaccacgttc
     1681 ttccgctccg acaccaggat aagcacctgc tgtattgata aaggtcacaa ctggacggcc
     1741 aaatttctca gcctgtttca tcaaccgcag tgcctttcgg tagccttctg gatgtggttg
     1801 gccaaaattc cgtttgaggt tgtcttgcaa actcttgcct ttttggatac caaccactgt
     1861 tacagcttgg tctccaagcc aaccaatacc accaacaact gcaccatcat cacgaaaaga
     1921 acggtcacca tgtaattgga taaattcatc aaaaatgcct gtcgcaaagt ccaaggttgt
     1981 caagcgactc tgctcacgcg cttctctgac tatttttgca atattcatct aggactccct
     2041 ccatgcaatc tgactaggct agcaatcgta tctggtaagt ctcttctttt gacaatagca
     2101 tccacaaagc catgttctaa taggaattct gccttttgga aatcctcagg caagctttca
     2161 cgaaccgtat tttcaatcac acgacgccca gcaaaaccaa ccaagctctg tggttcagcc
     2221 agaatgatat cgccttccat agcgaaagaa gctgtcacac caccagtcgt tggatctgtc
     2281 aaaatggtca ggtaaaagag accagcattt gaatggcgtt taaccgccgc agagatctta
     2341 gccatctgca tgagactcat gattccttcc tgcatacggg ctccaccaga ggctgtgaat
     2401 aggacaactg gcaatttttc gacagtcgca tactcaaaca aacgagtgat tttttcacct
     2461 acaaccgtac ccatagaagc catgataaag ttagaatcca taatcccaag agccacagtc
     2521 tgacctttaa taagagcagt tcctgtcaca acggcttcat gcagacctgt tttttcacgc
     2581 atagatgcca gtttcttttg gtaaccaggg aaatgcaagg gatccttgct ttcaatccct
     2641 gtaaacaatt ctttgaaggt tcccatatca atcgtcaaag ccaagcgttc ttgggcagaa
     2701 atacgaaagg tatagctaca gtgcggacag atacgttcac ttcccagatc cttctgatag
     2761 atggtatgct tacagcctgg acactgggaa aataattcat ctggaacctc tggcttagct
     2821 tgaggttttt ccctaaccga acgattggga ttgattcgaa tatacttatc ttttttacta
     2881 aatagagcca ttgattcccc ttttcggttt aaactcttaa agtcatttta ttctttttct
     2941 tgatatttag gtaagaaggt ttccatcaag aaggaagtat cataatcccc agcaatgaca
     3001 ttgcgatctg aaatgaggtc aagctggaaa tctgcattgg tctgcactcc ttcaatttct
     3061 aattcataga gggcacgttg cattttcatc aaggcgtcaa aacgattttc gccgtgtact
     3121 atgattttgg caatcatact atcataataa ggcggaatgg tataacctgg ataaactgct
     3181 gaatccacgc gcaagccaac tccaccactt ggcagataga gattagtaat cttacctgga
     3241 cttggagcaa agttaaaggc tgggttttct gcattgatac gacactcgat ggcatgaccg
     3301 cgtaggacaa tatcttcttg cttaacagac aaaggctgac ctgccgcaat gcaaatctgt
     3361 tccttaacga tatcaacacc tgaaacaaac tctgttactg gatgttctac ctgaacacga
     3421 gtattcatct ccatgaaata gaaattgcta cttgcttcat caagaagaaa ttcaatggtt
     3481 cctgcattct catagccaac aaactctgcc gctcgaacag cagcagcacc tatttcatga
     3541 cgcagcgttt ttccgattgc aatcgaggga ctttcttcca aaaccttttg gttattcctt
     3601 tgaagagaac aatcccgttc acccaagtga atcacatgtc catgctcatc acctaggatt
     3661 tgaacctcaa tgtgccgagc tggatagata acccgttcta tgtacatggc accattgcca
     3721 taattggcct tggcctcact agaggcagtt tcaaaggcag aaacgaggtc atctggtttt
     3781 tcaaccttac gaatcccttt accacctcca cctgctgaag ccttgagcat aacaggatag
     3841 ccaatttttt cagcaacaat caaagcttct tcagagttat gcacttctcc atctgaacct
     3901 ggtataacag gcacacctgc tttaatcatc tgagcacgcg cattgatctt atcccccatc
     3961 atatccataa catgaccaga tggaccgata aacttgatac ctacttcttc acacatggtc
     4021 gcaaatttgg aattttcact gagaaatcca aaaccagggt gaatagcttc tgcctcagtc
     4081 aagactgcag ctgatagaac tgcattaata ttgagataag actctgttgc cttgccagga
     4141 ccaatacaaa ctgcttcatc tgccaaaagc gtatgaagag cttccttatc agcagttgaa
     4201 taaaccgcta ccgtcgcaat ccccaattca cgtgccgcac ggataatacg aaccgcaatt
     4261 tcaccacgat tggcaattaa aatttttcga aacatggaga acctccttag ttcccaattg
     4321 caaaagtaag ggtaccactg gctgcaagct tgccatccac ttcagccttt gcttcaacca
     4381 cagctatggt gccacgacgt tttacaaaag tcgctgtcat aaccaattgg tcgcctggta
     4441 caacttgctt cttgaactta accttgtcca taccagcgta aaagaccagt tttcctttat
     4501 tttcaggttt tgataactcc aacacaccgg cagtttgcgc caaggcttcc ataatcacaa
     4561 cacctggcat aactgggtat tgaggaaagt ggccgttaaa gaaaggctcg ttgatggtca
     4621 catttttgat agcaacaatg gtatcctcgc tcacttccaa gacacggtcc actagaagca
     4681 taggataacg gtggggaaga gcttctttga ttccttgaat atcgatcatt tgatacgtac
     4741 caatccttta ccaaactcaa ccatttcttc gttagagacg agaatttccg ttaccacacc
     4801 atccttagga gctgggattt cattcatgac tttcatggct tcgataatta ccaatgtttg
     4861 accttttttg acactatcac caactgtaac gaaggcaggt ttatctggtc cagcagccaa
     4921 gtaaaccact ccaacaagtg gactctctac aagatttccc tcagtagcca cacttgcttc
     4981 agctggagct ggaacttctt ctgctacagt ctctgctgga gcagatgtag gagctactgg
     5041 actcggtgtt gctagaacgg gtgctggagc gacttgagtt gcaacttcag gcacaggtct
     5101 tgcttcattc ttgctaaact gcaactcatc cgtcccattt ttataagaaa attctctcaa
     5161 acttgactgg tcaaattgag tcatcaagtc tttaatatcg tttaaattca tacttatcta
     5221 ttctcccaac gtttgaaagc aagaactgca ttgtggcctc caaaaccaaa agtatttgaa
     5281 atagcgtatg gaatttcttt ctccaagcct tgtccataaa cgacattagc ttcgatataa
     5341 tctgatactt cacttgtccc agctgtcatt ggtacaaagt tatgacgcat agcttcgatg
     5401 gtgacgatag cttctactgc acccgcagcc cccagcaaat gtcctgtaaa agacttggtt
     5461 gatgatacag gtacttcctt accaagaaca gctacgatag caccactttc tcctttttca
     5521 ttggcaggag ttgacgttcc gtgagcattg acataggcta cttgctctgg agaaatctca
     5581 gcttcttcca aggctagttt gatggccttg atagctccct gaccttctgg atgtggagaa
     5641 gtcatgtggt aggcatcaca agtatttccg taaccaacca cttcagccag gatagtagct
     5701 ccacgttttt cagcgtgttc aagactttct agaaccaaca tccctgaacc ttcacccata
     5761 acaaacccat tgcgatcctt atcaaatggg atcgaagcac gagttggatc ctctgtagta
     5821 gagagagctg ttaaggcttg gaaaccagcg atggcaaaag gtgtgataga agcttctgtt
     5881 cctcccacca acatcacatc ttggaaacca aacttaatgg agcggaaggc atccccaatc
     5941 gcatcatttg atgaagagca ggcagtattg atagatttac aaacaccgtt tgcaccaaaa
     6001 cgcatggcta cattcccaga agccatattt ggtaaagctt ttggaagagt cattggtttg
     6061 acacgtttgg gtcctttttc atgaaggcga agtacctgat cttcaatttc cttgattcca
     6121 ccaataccag atgcaacgat aacaccaaaa cgatccctat taagagcctc tacatcaaga
     6181 ttggcatgat ttacagcctc ttgggctgca tacaaggcat ataaagaata gttatcaaaa
     6241 cggttggtat ctttttttac aaagtattta tcgaacggaa aatcttggat ttctgccgca
     6301 ttatgcacat caaagtcact atgatcaaat tttgtaatgc caccaatgcc gattttccca
     6361 gttgctaaac tattccaaaa ttcttctggt gtatttccga ttggagatgt tactccataa
     6421 cctgttacca ctactcgatt tagtttcatt cttttcacct ctagctttcg ctacatactt
     6481 aagccaccat caatggcaac cacttgtcca gttagataat cttggcctgc taaaaatact
     6541 gtcaaatctg caacctgctc tgcctgccca aattctttca tcggaatctg agctagtgta
     6601 gcttccttaa tcttatctga caggatagcg gtcatatcag actcaatcat tcctggagca
     6661 atcacattga ctcgtatatt ccgactagcg acctcgcgtg ccacagactt ggtaaagcca
     6721 atcaagccag ccttagaagc agcataatta gcttgaccaa tattccccat caaaccaaca
     6781 acactagaca tattaatgat agcaccttct ctggctttca tcatcggttt caagactgat
     6841 tgtgtcatat taaaggcacc agtcagattg accttgagca ctttttcaaa atctgcttct
     6901 gtcatcttga gcataagagt atcttgggta atccctgcat tgttgaccaa aacatctact
     6961 gaacccagtt ctgcaatagc ttgatcaatc atacgcttag cgtctgcaaa atctgataca
     7021 tctcctgaaa tgggaaccac cttgatacca tagtttgaaa actcagcgag caattcttct
     7081 gagattgccc cacgactgtt taagacaatg ttggctcctg cttgagcaaa cttgtgggcg
     7141 atggcaagac caattccacg actcgaacct gtaataaaga tatttttatg ttctagtttc
     7201 atttttttcc tttcaaaact tctacttatt ttagtctatt tttctaaaag tgctactaaa
     7261 ctcgcttgat cttccacatg agctaagtga gcagtttgat caattttttt aacaaaacct
     7321 gacaagactt tccccggtcc aatctcgata aagttgctta tgcctgcttc ttgcatgacc
     7381 ccaatacttt catagaaacg aacgggttcc ttgacctgac gcgtcaagag ctgagcaatg
     7441 tcctcttttt gcatcacagc agcttctgta ttgccgacta ggggacaagt aaaatctgaa
     7501 aaacttacct gagctagagt ttcagctagt ttctggctag caggttcaag gagagcggtg
     7561 tgaaagggac ctgacacctt aagaggaatc aagcgtttgg cacctgcttc ttgcaaaagt
     7621 tcaaccgctc gatcaactgc aaccacttct ccagcaatga cgatttgtgc aggtgtgtta
     7681 tagttggctg gagtaaccac tccaagttca gaagcttttt gacaggcttc ttcaatgacc
     7741 tctactggcg tattgagaac tgctaccatc ttgccagagt cagcaggagc cgcttcttcc
     7801 atataggctc cacgcttagc taccaaggca accgcatctt caaaatccaa ggcgccactt
     7861 gccaccaagg cagagtattc tccaagagac aaaccagcaa ccatatcagg ctgatagccc
     7921 ttttcttgca ataaacggta gatagcaacc gaagtcgcta gaatggctgg ttgcgtatag
     7981 cgggtctgat tgagtttgtc ttcttccgta tcgatgagat aacgcaaatc ataaccgagc
     8041 acctggctcg ctcgatcaat cgtttcttta acaatcggat actgatcata gaaatcccgt
     8101 cccatcccta gatactgggc accttgacca gcaaataaaa aggctgtttt agtcatttct
     8161 tacaactcct gtccagcgag aggcttcttc ttgaattttc ttagcggctc cgtaatacaa
     8221 atcttttagg atttcttcag ctgtttcttc tttagaaaca agccctgcga tttgacctgc
     8281 cataacagag ccaccatcca catcaccgtg aacaactgct ttggctagag cacctgctcc
     8341 catttgttca aagatttcta aatcaggatc ttcttgctta aaggcatctt tttcagccag
     8401 ttcaaaatct ctagtcaact gatttttaat agcacgaaca gcatgaccaa agtgctgagc
     8461 tgaaatcgta gtatcaatat cccttgcttt taaaattttc tccttgtagt ttggatgggc
     8521 attcgactct tttgcaacta caaaccgtgt ccccacctgt acagcctctg cacctagcat
     8581 aaagccagcc gcagcacctt caccatccgc aattcctcct gcagcaataa caggaataga
     8641 tatagctgtg gctacctgtc gcaccaaggt catggttgtt aatttaccga tatgcccccc
     8701 agcttccatt ccttctgcaa taacagcgtc tgcaccgatt ttttccatgc gtttagctaa
     8761 agcgacacta ggaacaacag gaataacgat tatcccagct tcatggaaac gttccatata
     8821 cttgcttgga tttcctgctc ctgttgtgac aactttaaca ccttcttcaa taacgagatc
     8881 cacgatgtct tccacaaagg gagataagag catgatgttg accccaaagg gtttatcagt
     8941 caatgatttg attttatcaa tattggcctt gacaacttct ttcggggcat ttcccccacc
     9001 gataattcct aatcctccag ccttggaaac agcccctgcc aaatcaccat cagcaaccca
     9061 ggccatccct ccttggaaaa taggataatc aatcttcaat aattctgtaa tacgcgtttt
     9121 catagtgcct ccaaccttcc ttgcttacgt aatagttcga tttcaccata atttgacagt
     9181 caaactatta cctaaacaag agggagtggg tttctcccta ctccttctac taatattctg
     9241 cttattttgc ttgctcttca acgtaagcaa ccaagtcacc aactgttttc aagtcatttt
     9301 ctgcttcgat ttggatatca aaagcatctt cgatttctga gattacttgg aacaagtcca
     9361 atgaatctgc gtccaaatca tcaaaagttg attcaagtgt tacttctgat gcgtcttttc
     9421 caagttcttc aacgataatt tcttgtactt tttcaaatac tgccatgata ggactccttt
     9481 aaaataaata gtttttttat aacaatgtgt tcaccacatg attacctaaa ttgtaagaat
     9541 gagcgtgccc caggtcaagc ctccaccgaa gcctgataga agaacagtct ggctaccatc
     9601 taaagggatg agaccttgtt ctacacactc tgaaagtaaa atcgggatac tggctgcact
     9661 ggtattgcca tattccatca tattggctgg aagtttggct cggtcaacac caatttttct
     9721 agccatctta tccaaaatac ggtcattggc ttgatgaagt agcagataat ccaagtctgt
     9781 cacctctata ggagattcat caatagtctg cttgatagac ttggctacat ctcgaatggc
     9841 aaaatcaaag actgtgcgtc catccatctt caaaaacgaa tctgcacttt cttgatctga
     9901 aaatggagaa tgtaaacctg aatgcccata agttaaacac tcgctgcgac ttccatcgct
     9961 attgagactc tcagctaaga aatgctcttg ctcgctagct tctaacaaga caccaccagc
    10021 accatctcca aacaacacag ctgttgatcg atccgaccaa tcgactgcct tagagagggt
    10081 ttcactacca atcaccaagc ctttttgaaa gcgaccagaa gcgataaact tttcagcagt
    10141 tgaaagagca aatacaaatc cactgcaagc cgcggttaag tcaaaagcaa aggctttatt
    10201 agcaccaata ttagcttgaa cacgagcagc tgtagagggc atcatcgaat ctggagtaat
    10261 ggtagctagg atgataaaat ccagttcttc tcctgttatt ccagcttttg ccatcagttt
    10321 cttagcaacc tctgtagcca aatcactggt agattctgtt cttgaaatat gcctttgtcg
    10381 tattcccgtt cgacttgaaa tccactcatc attggtatcc ataatctgag ccaagtcgtg
    10441 atttgtaacc acttgctctg gcacataatg agcaacctga cttatttttg caaaagccat
    10501 tatttcaaat cctccaaaaa ttggtaaaga ttagtcaaac ctttacccat gacagcaatt
    10561 tcttcctcgc tcatgccatc aataattttt tctaccatgg ccttgtggaa gcgtttatgc
    10621 agtctatgaa tcaagcgacc cttctttgtc aaatgcagat gcaccacacg acgatcctgt
    10681 tctgaccgaa ctcgctcaat gtagccctta cgctctaaat tgttcaaact tgtcgtaaca
    10741 gttccaagag ttaccatcaa ctcttttgac acttgacttg gagtcacgtc tggagcctta
    10801 ccgatgacat caatcgtatg catttctttg atggagatat ccttaaaacg actacctctc
    10861 aagttcactt cctcaattac aaggacattg ttaaatatag atgttaaata ttcattgatt
    10921 cgttggtagt ccatttttca tatccctcct tcttcaaaaa acttttacaa tcaaaacatt
    10981 tgacagaaag aattatatca aaattcaaag aatgatgcaa gtatttttta ttttcctgta
    11041 aatttaggtc ttcttctctc cgaatgagct cgcactcctt ctttgaaatc ctctgtttga
    11101 gctaaggatt tctgtaggtt cagttctaaa gtagcgtaac cctgccagtc tttaaattgg
    11161 ctctcccaaa ccaacttctt aatggcagca taggaattac ttgaagcacg tcttaatttt
    11221 ttaagaagct gttctctcgt cttttcaagt ttttcagctt cagaaacgcg gtaaaccaac
    11281 ccccattcta gggctttttc tgccgttaaa gcctctcctg tcatagctaa ttgagcagca
    11341 cgcgtcacac cgatactgcg gctcaagaga tgaatccccc ctgcatctgg agccaaacca
    11401 acaccaacaa aggcttggat aaacttagcc ttatccgtcg ccaaacagaa atctgccgca
    11461 acagccatat tcgctgcggc acctgcaaca gcaccgtcaa cttccattaa aacaggtttg
    11521 gctatttgct tgattttata agaaatcgta ttgaccaact ctgcgatttt tgtcaatgat
    11581 ggaatatcat cctcatccac tgcccgcttc atctctacca aatctccccc aactgagaag
    11641 acctttccat tggcattgat taagataaaa tgcacagctg gattttcttc tgccaaagtc
    11701 agagcttcta aaatctcctc acacatggga atatgaaaac catttgcgac ctcaggacgg
    11761 ttcaaggtaa ggattgccaa gtcctcttca agttgataaa taatgtgttc catcagggct
    11821 cctttttatt ttataagcag tttatactct tcgaaaatct ctttaaaccg cgtcagcttc
    11881 catctgcaac ctcaaaacag tattttgagc tgacttcgtc tagcttctta gtttgctctt
    11941 tgattttcat tgagtgttaa attatttcac tgtcaaagta tatctttttt aggagcagaa
    12001 agcaagaaaa aatcgactga aagtgtctca gccgataaga aaggctcgct ttaggctaga
    12061 aagcatctta ttttcttcat tgaaaaaagc ctttctttct gctataatcg tataaaatac
    12121 ttactttagg agttcttatg aaagttgtta aatttggagg tagttctctt gcctctgcta
    12181 gtcaattaga aaaagtttta aacatcgtca aaagcgattc agagcgtcgt tttgtagtcg
    12241 tttctgcgcc tggtaaacgc aatgctgaag atactaaggt tacggatgcc ctgattaaat
    12301 actaccgcga ctatgttgcg ggtaacgata ttagcaagaa ccaaagctgg attatcgacc
    12361 gctatgctgc tatggttagt gaattgggac taaaaccagc tgtgctagaa aaaatttcta
    12421 aaagcattca cgccttggcc actcttccta ttgaagaaaa tgaatttctc tacgatactt
    12481 tcctagcagc cggtgaaaat aacaatgcca aattgattgc tgcctacttt aaccaaaatg
    12541 gtatcgatgc acgctatatg caccctagag aagctgggat tgtggtcaca agtgaacctg
    12601 gtcacgctcg catcattcca tcaagttatg acaagattga agaattgaca aacaccaatg
    12661 aagtccttgt cattcctggt ttctttggtg tcactaagga aaatcaaatc tgtactttct
    12721 cacgtggagg ttctgatatt acaggttcta tcattgctgc tggtgtcaaa gctgacctct
    12781 atgaaaactt tacggacgtt gatggtatct ttgcagccca ccctggtatt atccaccaac
    12841 cacactcgat tcctgagttg acctaccgtg aaatgcgcga gttggcctat gcaggcttct
    12901 cagtccttca tgacgaggct cttcttcctg cctaccgtgg aaaaattcct ctggttatca
    12961 agaataccaa caaccctgac catccaggta ctcgtatcgt tctaaaacac agtaatgatg
    13021 aatttccagt tgtgggaatt gctggtgact caggctttgt cagcattaac atgtcgaaat
    13081 acctcatgaa ccgtgaggtt ggatttggcc gcaaggttct gcaaatcctg gaagaactta
    13141 acatcggttg ggaacatatg ccaacaggta tcgacaatct ttctatcatt ctccgttctc
    13201 gccaactaac tcccatcaag gaagaagaaa tcctgcgtca gttggttcaa aaggctaaag
    13261 tagatcatgc agaaatcgaa cacgaccttt ctatcattat gattgttggt gaaaaaatga
    13321 agagccatat cggagtgact gctactgcga cacgcgctct atctgaaaac aaaatcaaca
    13381 tccagatgat gtctcaaggt tctagtgaag tttctattat gtttgttgtc aataaagacc
    13441 aagagaaagc agcaattaaa gccctctaca atgccttttt tggagaaagt aaggaagact
    13501 aagcatggcc caatcactta acaaaacagt actcctcagt acgacaggca cttcctacct
    13561 ctctatcgct gggaaagttg ggaaattcct tgtcggagat caggctttgg aattttaccc
    13621 agatgtcaat gtcgaacaat ttatccagat tccttggagc catatcaatc agattggagc
    13681 caatgtcact ggacgcaaaa tcagccgcca cttcgaagtc tttacagaca aaggaaaatt
    13741 cctctttgct tcaaaagact caggtgccat tctcaaaatt gcacgcgaaa aactaggcaa
    13801 tgacaaggtc gtcaaacttc cgaccctgat tcagacaatt agccaaaaat ttaaaaatct
    13861 atttgcaaaa aagtagaaac tttagtataa tcatagcaac ggataagtag gttatcttct
    13921 tctttcagaa agtctgcggg tactgcgagc agataggagg gataggtgaa attctaccgt
    13981 tagtgacaat tacatacaca atcaagtgca cacctgtgaa gttggatgga accgtggccc
    14041 tgccactcca acgttttgtc agggtgcttt tttcataaag gagttcttat gttagatatc
    14101 aaacgtattc gtacagattt tgaagctgtc gcagaaaaat tagctacacg tggtgtagat
    14161 gctgctgtct tgaatgaaat gaaagaaatc gatgctaaac gtcgtaacat cttggtcaag
    14221 gttgaaactc tcaaagcaga acgtaacaca gtttctgctg agattgccca agctaagcgc
    14281 aacaaggaaa atacagatga caagattgct gccatgcaaa atctatctgc tgaggttaaa
    14341 gccttggatg ctgaattggc agaaatcgat gctaaattga cagaatttac aacgactctt
    14401 ccaaatatcc cagctgacag cgttcctgtt ggggctgacg aagacgacaa tgtggaagtt
    14461 cgccgttggg gtactccacg cgagtttgac ttcgaaccta aagctcactg ggatctcggt
    14521 gaagaccttg gtatccttga ctgggaacgc ggtggtaagg taacaggcgc tcgcttcctc
    14581 ttctataaag gcctcggtgc tcgtttggaa cgtgctatct acaactttat gttggatgaa
    14641 catggaaaag aaggctatac tgaagtcatc acaccttaca tagtcaacca tgattctatg
    14701 tttggtactg gtcagtatcc aaaatttaag gaagatactt ttgaactcag cgataccaac
    14761 tttgtcttga ttccaactgc tgaagttcct ctgacaaact actaccgtga tgaaatctta
    14821 gacggcaaag atcttccaat ctacttcact gccatgagtc cgtcattccg ttctgaggct
    14881 ggttctgccg gtcgtgatac gcgtggcttg atccgtttgc accaattcca caaggttgaa
    14941 atggtcaaat ttgccaaacc agaagaatct tacgaagaat tggaaaaaat gacagccaac
    15001 gctgaaaaca ttcttcaaaa actcaacctt ccataccgtg tcgttgctct ctctactgga
    15061 gatatgggct tctcagctgc gaagacttac gacttggaag tgtggattcc agcacaaaac
    15121 aattaccgtg aaatctcaag ctgttcaaac acagaagatt tccaagcccg tcgtgcccaa
    15181 atccgttacc gtgatgaagc agatggcaag gtgaaactcc ttcatacctt gaacggttct
    15241 ggacttgcag ttggacgtac agtggctgca attcttgaaa attaccaaaa tgaagatggt
    15301 tctgtgacca tcccagaagc acttcgtcca tacatgggtg gagctgaagt catcaaacca
    15361 taaaaaataa ggtttagcta tttctagcta gacctttttt cgtaaccaaa tcagataagc
    15421 acctagtaca aagaataaaa tagttaggca tataatggtt tcagccaata ccaggtaatc
    15481 cagaaatgga agtttcaaaa ttccctgagc catcttgagc gaggtcgctg tgataatggt
    15541 tgggaaggtg agggctgaga aggctggttg aaaaccttgt tttaaaatgt tgggcagacg
    15601 agttaaaaca aagaaaaaga aggattgaga agccaaaatc atgacaatca agacccaagt
    15661 cggcaggctg gttcctccta ctcgaactag agaagccaag agtagagaga aaggagcaca
    15721 gtagattcct tcttgtccaa gcaaggctag tgggagtgga tgtttcttta aatcgctata
    15781 aataagggga tagagataga aggtcaagag aaaaccaaaa ctcaaggtcg cataggcaat
    15841 ttcgataata cctaccagag gataggtcaa ggcagccact gctatcccca catagagaac
    15901 cgtccagctt ggagtggcat gaaccctccg ccctggacaa gcaaacttga tggtaaaacc
    15961 agcaatcaag gtcaaatcca agagaaatga aaaccaccaa atcccttgtg ctaccaaagg
    16021 aagataagag aatacgcgaa agacataggt cgataaaatc atcccagcca taggaaaggt
    16081 tgccattcct gacaaaagag ggggcttggt caattcttgc ttggtttctt tccaattaaa
    16141 gagatgcaga attagaaagt aaatccataa aaccaaacca atcagactaa aaagatggga
    16201 tagaaccggc aacgtatcta aaataagatt tccagctcct gccaaaccta gcaaacaacc
    16261 tgaaaatact aaggggagtt ttttcatcct aacctccaat aatcatgtta gtttcagtat
    16321 aacataaaag cgcttaaatg aggatttaaa aaaacgaagt ccgcttattt cagacttcat
    16381 tttactcaga tatgaattag gcataaggtt gcaattctgg attaattggt gtattagcta
    16441 agttgttggc atagttacag aggattgcta ggctgacacc aaaaaccaca tccaaggcat
    16501 tttgttgagt gtagccagct tctaaaaact cagacaaggc ttcatctcct acacgaccct
    16561 tggtattgat aactgccaag gtaaacttag ctagggtatc caatttagga tctgtttcaa
    16621 ttggagtacg attgcgaaga gcttgaatca agtcatcatt catctggatt tgtttgatgg
    16681 aaaaggctgt gtgacctgcg acacagaagg cacaaccatt ggtcacggct gccgtgattt
    16741 gcaccacttc acgctcaacg ggtgtcaggc tgttgcgacg gtggatagat gagacaattt
    16801 ggtaggcttc taaaacagtc ggggcattgg ccaagagacc gattaggttg ggaatatagc
    16861 cattgttgtc tttttctact gtttcaagaa tttctttcac ttctgctggt gctgactcta
    16921 ctgtatggat agtaaatgtt gtcataagat acctcttttc ttattattga cactaatatt
    16981 attggaaaat cttataaaat cctgattcct aagtttatct aagataaagc tttattctct
    17041 cataagattt tcgttgttat attagtttat cacacttcca atcacttgta taatatatat
    17101 tatatatcag gctgataaaa attatttata ggcaaaaaaa tcacacgagc tgtgtgattc
    17161 cattatttgt caaaatactt tttagtttca gcaataacga ctggcgacaa gaccaagagg
    17221 gcaatcaagt ttggcagagc catcaaggcg ttaacgatat ctgcgataat ccagaccata
    17281 tccaactcga taaatcctcc taacaagacc atgagcacaa aaaccacacg gtagagccag
    17341 ataaagcgaa ccccaaagag gaactcaaaa cagcgttctc cgtaatagtt ccaacctaga
    17401 atcgttgtaa aggcaaaaag tacaaggaag atggtcaaga gagcaggccc aaagtgtgaa
    17461 aagtttgttg agaaagctga ctgagtcaag gcaaccccat tcaagtcacc gctccaaact
    17521 ccagttacca agatggtcaa accagttaga gtacaaatga tgagggtatc aataaaggtt
    17581 cctgtcatgg aaatcaaacc ttgctctact ggttcatttg tcttggcagc tgcagctgca
    17641 ataggagcag aacccagacc agattcgttt gagaacacac cacgcgccac accattttga
    17701 atagccatcc gaacgctagc accagcaaat ccacctaccg cagcaagggg actaaaagct
    17761 gaggtaaaga ctaaagcgat tgtgccaggg atttttccga tattaaagaa aataactgta
    17821 agagttccta agatataaat gatggccata aaaggaacaa cagtagttga aaccttagaa
    17881 atagacttga gtccaccaaa gactgcaatc gctacaaaga cagacaagac gagagctgtg
    17941 atggctggcg aaatcgtcgt tgtattttgg atagattctg caatcgagtt gacttgggtg
    18001 aaggttccga ttcccaagag agcaaccaat actcctgcta ctgcaaacaa aacagcaagt
    18061 ggtcgccact tttctcccat ccctagaagg atataatgca tgggacctcc cgctactgca
    18121 ccatggtcgt ccttggtgcg gtatttgatg gccaagagtc cttccgcata cttggtagcc
    18181 attccaaaga aagccgccat ccacatccaa aatagagctc ctggtccacc aaccttgata
    18241 gccgtcgcaa ctcctatgat atttcctgtt ccaacagttg atgccaaggc tgtacacaga
    18301 gctgcaaaac tggatacatc accatgtccc ttatcctgga taaaaataag ctgaaaggcc
    18361 ttgggtagac gcaaaacctg caagagtcct agccgaatag ttaggtaaat ccctgttccg
    18421 accaataaaa tcaagagggg cggtccccaa gcaaaagcat cgattgattt aagcaattct
    18481 aacatttcct tctcctatcg tttcaacccc aaaagaaaga gcacatgcaa gatacatgta
    18541 ctctggaatg cttagataaa tgctaaaaag cggtctatcc tagctctgtc cttttacctg
    18601 agagtttgag cagttgcctg ccttgcccct tcggtgcctt tacggtctct ccagagttcc
    18661 gtccatttac agtcatggaa aatcaaacga ttccccactt ctattaaact tcattcggtg
    18721 ttggtattta attgattcta attttacaaa aaatgttggc ttttgtcaat gtgtttatta
    18781 gtaaaaatta gttcaacagt ttttacttta taaagtccag aatactgcta tcctttaaaa
    18841 gtgacaatag tcgcaccact gcctccagca ttttgtgggg catagccgaa actcttgaca
    18901 tgtttgtttc tttgcaagta tttggtaact ccttcacgga tgactcctgt tccgatacca
    18961 tggatgatat caacttgagc catattgtta agcaaggctt ggtcgatgaa ggtatctagc
    19021 tcattcatgg cttcttcata gcgcttgcct cgaagatcca gtctagcttg aggtcctcgc
    19081 ccagaagttc gtttcacaac attgacctgt ttcttcttga ctggtttttc ttgctgggct
    19141 tgaacaagat caaactcttt ctcttccaag gtcatcttaa tcaagccaac ttgggcttcc
    19201 cagcgaccgt ccttgagttg actggtcaag gtaccacgct gaccataact gagaaccacg
    19261 atatcatctc ccacctttgg agctcgtttt ttcttggcct tttgaaggac cttattttta
    19321 gacaagtcca ctttttcagg agccaatttt ttcaacttgg ccttggcttc aatgatttcg
    19381 tggggcttga gttgggattt actgtggaga tttttgagaa tctggtcact ttcacttagg
    19441 gccatatcca caatctcagc agcctgttca cgcgccttgt taagctcggt ttccttttca
    19501 cgattaagct cgttgtagag tttttttagc gcacggttca tcttgagatt ttcttgctcc
    19561 acctcacgga tattgtccaa acgtttgcgg ctttccagcg tctgctcttc taattgctca
    19621 atgatacgat tgacgtcatt gtcctgatcg atctgctgac tggcatctcc tacgataact
    19681 tcagataggc ctagacgttt ggcaatttca aaggcattac ttcggccagg aacaccctgc
    19741 ataaagcgat aggtcgggcg aagagttgca gtatcaaact ccatactggc attttgcaca
    19801 aaggctgtct caataccgta ggccttgagt tctggatagt gggtcgtcgc catggtcttg
    19861 atttgacgca ggcgaaggtc ctccagaata gccatggcaa gggctgctcc ctcttgggga
    19921 tcagtaccag cccccaactc atccaaaagt aagagtgaat gttggttgac cttgccaaga
    19981 atatccacga tattggtcat atgactagag aaggtagaca agctctgctc aatagactgc
    20041 tcatctccaa tatcagcaaa gatttcttca aaaataccaa cacgacttcc cttgtctgct
    20101 aaaatcggca atcctgactg ggccatgacc tgtgtcaagc ccagagtttt gagcatgatg
    20161 gtcttcccac ctgtattggg acctgtaatg acaatagctg ttaaatcttg accaaaatag
    20221 acatcatttg cgacggcatt tttgaccaaa ggatggcaga catggagcag ttgaatctct
    20281 tgattttctg acagctgagg cacgactgct tgtctttctt ggataaatcg aaccttggca
    20341 cgaatcaagt ccagatgacc gataatccaa gcgtcattag caatctcagc cgcatgaggg
    20401 cggacacgct cagaaatttc ttggagaatg cgaagcattt catagcgctc atctgctcgc
    20461 agactagcaa tttcttcgct cagtttgact acctcacggg gttcgatata gacggtgttt
    20521 ccactagcag aaatatcatg aacgacacct gcaatcttat tgcggtaggt gtttttgact
    20581 ggtaaaacct gacggccatt tctgctagca acaattcctt ccgtcaacag ctgcgctttt
    20641 tgcttgagca agtcttgtaa aacatcgcgt acctgactct cgctatcatg tatttttcga
    20701 cggattcgcg ccaattcttc actggcaaaa ttttcaatga aacccgcatc attaaaggcc
    20761 tgaagatttc cttgtaattg cggaaaatca tgtaatttct caaaccaaag ggctaattct
    20821 tccaagctga cattttccag attggtgtaa aaattttgaa gttctcggct ggcaagaagc
    20881 acgcgtttca agagtaggaa ctcctcgata ttgagatccg ctcccatctc caacctcttg
    20941 cagactcctg caatttcctt agttgagaga atagtaaaat gcggttgctc gacgaaaaga
    21001 gcctgcattt ccttcatctc agcaaaagcc tgtttgattt tatctgcttt ggcagtcgga
    21061 gccagttgtc tcaattgctc caagccctgc tcggtcaaca aatgaggctc aaacaaggcc
    21121 ttgaccttat cgaactctaa tgtttctaat attttcttat tcatctttat ttccttgtct
    21181 ttgaatgtct aggtgtggta gctttttaca ttctgataga ttcgagtcaa atctgtaaac
    21241 aaagggctag gaaaactcct gcccttttta tccgattaaa tttgtcaccc agatttgttt
    21301 gagccaactg gttgttaccg gtatgctctg gatgatgtgt tttgcgacga tactcttttc
    21361 aagaggattt tgtataactg ccatggggat ggtcgccaag attgtcaagg ccatttgcaa
    21421 gacaaataag gtcaccaaca tggacaagat acctgctgaa acttggaaca acttaccacc
    21481 cagttttttg ctaggaatca agtgtaagag aagaccaagt aaacgaccaa tgctatagac
    21541 aatcccaaat acaagcaagt agccgatacc tgcataaaag accttatcca gctgaaagag
    21601 ttgatccgat gggaaaaaga aagtcccctg accttcctgc gaatttgcat aagggagcaa
    21661 taaatggaat tgctctccaa gccccttata aaactggcca gccataaaag ccgatgccat
    21721 ggctgaaatc aggtaataaa cctgtaagag caggcctctc cgatagccga tataaaatcc
    21781 ccaaaccaag accaatagaa gaaggaatga aatcataagg aatcctcaat cttgctctgt
    21841 tcttgcttac aagtcacaag cttgtgacgg agttcttcta gctcttgctc cttatcgtca
    21901 aattcaatct cacggctgag ctgagttgat aaacagttga ctgccaacaa aagagcgatt
    21961 gtttcatcat ctgcgctagg catttgttct ttaattgctt ggtatttttc tgtcgcaacc
    22021 ttagcgattt cctccataaa aaggttgtca tgttcgcttg tcaaggttaa cgattttttc
    22081 ccgaatgtaa atttgaatcg atttagattt gccataaaat tcacctcacg atattatacc
    22141 aaaattcgct aattttgtca gtttttacaa attttactgc ttttgtggta caatagaaac
    22201 tatggcaagt atcacactca caccaagcga aaaggatatt caggcttttc ttgaacacta
    22261 tcaaaccagt ctggctccta gcaagaatcc ctatatccgc tactttttga aactacctca
    22321 agcaacggtt tctatctata cttctggaaa aatcttgctt cagggtgaag gggctgaaaa
    22381 atacgccagt ttctttggct atcaagctgt agagcaaacc agcggacaaa atcttccttt
    22441 aattgggaca gatgaggtgg gaaatggttc ctactttggt gggcttgcag ttgtggctgc
    22501 ctttgtcaca cctgaccagc acgacttttt acgaaaactc ggtgtggggg attctaagac
    22561 tctgaccgac caaaagatcc gtcagattac tcctattctc aaggaaaaaa ttcagcacca
    22621 ggcactcctt ctctcaccca gcaagtacaa cgaggtcatc ggagaccgct acaacgctgt
    22681 ttcggttaag gttgccctcc ataatcaggc tatctatctc ctccttcaaa aaggtgttca
    22741 gcctgagaaa attgtgattg atgcctttac cagtgctaaa aattatgaca agtacttggc
    22801 acaagaggcc aatcgtttca gcaatcctat cagcttagaa gaaaaggctg agggcaaata
    22861 cttgtctgtc gcagtttctt ctgtcattgc gcgtgatctc tttctggaaa atcttgaaaa
    22921 tttgggacga gaactgggtt atcagctccc aagtggagct ggaacggctt ctgacaaggt
    22981 ggctagccag attttgcaag cctatggtat gcagggactc agcttctgcg ccaaattgca
    23041 ctttaaaaac actgaaaaag cgaaaaaacg cttagaaagg taagttatga attcatttaa
    23101 aaatttctta aaagagtggg gattgttcct cctaattctg tcattactag ctttaagtcg
    23161 tatctttttt tggagcaatg ttcgcgtaga aggacattcc atggatccga ccctagcgga
    23221 tggcgaaatt ctcttcgttg taaaacacct tcctattgac cgttttgata tcgtggtggc
    23281 ccatgaggaa gatggcaata aggacatcgt caagcgcgtg attggaatgc ctggcgacac
    23341 cattcgttac gaaaatgata aactctacat caatgacaaa gaaacggacg agccttatct
    23401 agcagactat atcaaacgct tcaaggatga caaactccaa agcacttact caggcaaggg
    23461 ctttgaagga aataaaggaa ctttctttag aagtatcgct caaaaagctc aagccttcac
    23521 agttgatgtc aactacaaca ccaactttag ctttactgtt ccagaaggag aataccttct
    23581 cctcggagat gaccgcttgg tttcgagcga cagccgccac gtaggtacct tcaaagcaaa
    23641 agatatcaca ggggaagcta aattccgctt atggccaatc acccgtatcg gaacatttta
    23701 agaaacctaa gaggcagaga atcaccaatc tcagcctctt cttctatcgt gagaagtgat
    23761 tgtttattta caaatactca atgaaaatca aagaacaaac taggaagcta gccgtaggct
    23821 gcttaaaaca gtgttttgag gttgtggata gaactgacga agtcagctca aaatactgtt
    23881 ttgaggttgc agatggaagc tgacgtggtt tgaagatatt ttcgaagagt ataaaataaa
    23941 aacaatccca actctcacct attcatgcaa aggaatttta tggaagttta tttttcagga
    24001 actattgaac ggattatttt tgaaaatccc agcaattttt atcgcatcct cctcctagaa
    24061 atcgacgata cggacgcaga ggattttgat gattttgaaa tcattgtcac aggaaccatg
    24121 gctgatgtaa ttgagggcga agactatact ttttgggggc aaattgtcca gcactccaag
    24181 tatggagaac aactgcaaat cagtcgttat gatcgcgcaa aaccaactag taagggcttg
    24241 gtcaagtact tttcaagtag ccatttcaag gggattggtc tcaagacagc tcagaaaatc
    24301 gtggatacct atggcgaaaa taccattgac gaaattttgc aacacccaga aaagttagaa
    24361 ggcatcgcag gactctctgc caaaaatcgc gaggctttcg tctccactct ccgtctcaac
    24421 tacggaacgg agatgatttt ggccaaacta gccaactacg gcattcccaa caaactagcc
    24481 tttcagattc aagactttta caaggaagaa acccttgatg tggttgaaaa ttatccctac
    24541 cagctggttg aggatatcaa gggtttgggc tttaccattg ctgaccaact agctgaggaa
    24601 ctaggcatcg aaagtcaggc tcctgaacgc ttccgcgccg gtctagttca cagtcttttt
    24661 caggcctgta tggaaacagg ggacacctat gttgaagcac gggatttgct ggaacaaacc
    24721 cttactctcc ttgagtcttc ccgtcccgtg gaactagacc ccagccaagt tgcccaagag
    24781 ctctcctacc tgatcgaaga agacaaggtt cagcagattg ataccaagat ctttgacaac
    24841 agcctctttt tcgctgagga aggcatccgc agtcacttgg ttcgtatcct tgaaaaagga
    24901 aaacagaaga gtcatgattt agaaaccatt caaaaacata tcactactgt cgagcaagaa
    24961 ctgggaattg agtatgataa cattcaaaaa caggctatct gtgatgctat ccagaataag
    25021 gtctttatcc tgacaggtgg gcctggtact ggtaagacaa ctgttatcaa tggaatcatt
    25081 gctgtttatg cccttttaga aggacttgac ttcaggaaga aaagcaatct gcccattctt
    25141 cttgctgctc caactggtcg agctgctcgt cgcatgaatg aattgacagg tttgcctagc
    25201 gcgaccatac atcgccactt gggaatgaca ggtgacgatg ataccagtca tctggaagat
    25261 tacctagatg ctgactttat catcgtggat gaattctcta tggtagatac ttggctggcc
    25321 aatcaactct tctccaatat ctcttctaac agtaagatcc tcatcgtagg tgacagtgat
    25381 cagctacctt ctgtcagtcc tggacaggtt ctagcggatc tacttcatat tcctttgatt
    25441 cctcagactc gcttggaaaa aatttatcga caaagcaaag aatcaaccat cgtcacccta
    25501 gctagtcaga ttcgacaggg catcttgcca gctgatttca cccaaaaaaa agctgaccgt
    25561 tcctactttg aaattgctag tggccatatt cctgccacca ttgaaaaaat cttaggtgcc
    25621 gccctcagaa atggtattcc cgcccgtgat atccaagttc tggctcctat gtaccgaggg
    25681 acggcaggga ttgatgctat caatcagctc atgcaagacc tgctcaatcc cccacaaaaa
    25741 gatcaactca gttttgaagc tcctcagtgt cactatcgta agagagacag ggtcattcat
    25801 ttggttaacg atgctgaaat caatgtcttt aatggggatt taggagctat cacagacctg
    25861 attcctggta aatacaccga atcgaaacaa gacgagattg tcattgattt tgatggtaat
    25921 gaagtctctt acccccgtaa cgaatggtac aagattcgct tggcctatgc catgagtatt
    25981 cataagtctc agggaagtga gttcccagtt gtcatcctac cgattactag tgctagccga
    26041 cgtatgctgg agcgaaatct catctacaca gccattacac gtgccaaaag caaactcatc
    26101 ttactaggcg aattacaagc cttcgactat gctacccaac acatcggaac tgcccgaaaa
    26161 acctatctga ttgaacgctt cagtgatcta ctggagaatg ttgaagaaaa gcaacaagct
    26221 gtctctgaaa cagtcacatc aagtgcctct gaacaatcct acatcctaac cgaagaaaac
    26281 tgggaccgca tcccagccat gattgggatt acagacacag acctcaaaga gatttttgga
    26341 aaatagtgca tcagaaaacc caccaattca ggtgggtttt ctgtttatta agattatttt
    26401 actgttgctg tgcttgtgat caattcaaca gcttttttga tagtgatatc atgtttcaac
    26461 atgtcagctg aaagcaagtt ttgaacttgt gcaacttcca tgttgtagtc tgctgccaat
    26521 tgctcaactt ctttttggat ttcttcttct gaagcatcaa atccttcagc tttggcaact
    26581 gcttcgataa caaggttagt cttagtacgt gactcagctt ctgcttggta ttggttgtga
    26641 aggtcttctt gagtagttcc agtgatttgg aagtacatgt cagggttgat cccttgacgt
    26701 tgcaaattcc caaggaattc atttactgaa cggtgaactt cttcatggat catttcttct
    26761 ggaagttcta cgatttcagc attttctaca gctgtatcaa ttgctgcacc ttcaactgca
    26821 tctttgtaag cttcttcttt agcagcagcc aattctttgc tgtatttttc tttcaagtca
    26881 gcaagtgttt caacttcttc atcaatgtct tttgcaagtt catcgtcaag agccggaact
    26941 tctttagctt ttacttcgtg gatagttgtc acgaatttag cttctttacc tgcaaggtct
    27001 tctgcttggt agtcttctgg gaatgttacg ataacatcaa cggtttcgcc agctgagtga
    27061 cctaccaatt ggtcttcgaa accagggatg aattgacctg aaccaagtcc aagtgagaag
    27121 ttttcacctt ttccaccgtc aaattcaaca ccgtcgatag aaccaacgaa gtcgatcaca
    27181 acagtgtcgc cgttttcagc agcagcttcc ttgataacca attcagccag gttgttgcgt
    27241 tcgcgttcga tacgctcttc gacatcagcg tcagttactt ctttttctac atcaactgat
    27301 acttcaaggt ttttgtagtc acccaatttt acttcaggtt ttgtaacgac ttcagcagtg
    27361 ataacccagt cttgaccttt ttccattgaa gttacgtcaa tttttggttg ggcaaccact
    27421 tcaagaccag cttcttttac agctgcttca taagcgtttg gcaaaagtgc gttcattgca
    27481 tcttgataaa gagcttcttc accaaatttt tggtcgaaga tagggcgtgg aaggtgacct
    27541 ttacggaaac ctggaacatt aagagatttc ttcactgact tgaagacacg gtccaattct
    27601 ggtttgattt ggtcttgaga gatagtgaaa gtcaagacac cacggtttgt ttctttgttt
    27661 tcaaatgata cagacattct gtcatttctc cttaaaattt tttaaataca gtctattata
    27721 acattttcta taaataaaat ctagactaat gcagacaatt atagacaaca agcctttttc
    27781 ctaactaaaa cactcataaa gtatagacaa ttttagacta ctttggatat cttttggtta
    27841 gtcattttcc aaaactaatt tatctaattt ttcagttata tagtagattg aaactagaat
    27901 agtacacctc tacttctaaa acatttttag aaatcgattt gactgtcctg atcgatttgt
    27961 cctgttcttg tttcatttta ctatatagat cgcattcgaa agaattcgtt ccaaaattgc
    28021 ttggttcgtt cttctcttgg acgactaaag aattgatggg cattattttt ttcaacaatt
    28081 ttcccactgt ccataaaaat aacatgatgg gctacatctc tagcaagacc tatctcataa
    28141 agctgatcaa aaactcaatc tgaggagaaa atccaataag gctttccata ataaaggaca
    28201 tcctatcaag atttttgaac acccgatagg ctgccttttc ccgattttga agactttttg
    28261 tccagcttct tttaccttat aaataacaac aaaaatcaaa gacaagctag aaagattacc
    28321 gcagataact caaacagtgt tttgagattg cagataagac tgacggagtc agctcaaagc
    28381 actgctttga ggttgtagat agaacaacat atgcctaaga caaagcgatg ctaacctgat
    28441 ttgaagagat tttcgaaaaa gattaaatat actctacaat ttgctcaatc aattcttggt
    28501 cgtctaaacc tgtaacttgt ataacaacat ctttgactga ttgtttagcc aacaattcac
    28561 ctaatcgaat actttcttca tcatttacat cgcgatagtc aaagacatag ccaactgttt
    28621 taagtaggtt tttatatgac aaactgagtt ctttcaattc acgtatcggc cggatgaatc
    28681 gttcattata gcctaatttt cggattggag tacgagctac gcgactaacc tcgtccacta
    28741 tgaaagggtt ttcaagtcgt tctataatga ctttgtgata attctccaat tcttttttat
    28801 caaagttcca tttggcaatc aagagactcc gaatttcagc taatacagat tcaatccgag
    28861 atttaatatt aggattttga agagcttcca aaattgtctt ggcaccataa tgcgcaccaa
    28921 tgtaagctga agttgcatgt ccagaattga ctgaaaaaag ttttcgctca ataaagggtt
    28981 ctaaatcttc ttcataatgc acatctttta gacgtaaatc tggattttta agacgcttgg
    29041 tttccacgac ccattcatta aagggctcga ccacaacaaa aagggaatct tcgtgacttt
    29101 gtgctggaac aatcctgtct actgcagcat ttggaaaacc tatgtagtta tcagcaaatg
    29161 tcaaaccttc cggacttaaa tatttcttga cttcttgata aagaaattga gacccgccaa
    29221 tcatattttc acaggccata acatccaatg cctgtgtatt tcctgcaact cggcgagctt
    29281 cgattccttt ggctagaagt tcggcgataa aagggagtat attaggtccg attgcagtag
    29341 taataatatc cgtcttttga atcgcttcaa tgacttgctc aggatgttct ttgctattaa
    29401 tgccagccac attagttact tctatacgag actgtccttt ctgtgcaatt tcaatttcat
    29461 acttgccctt ttcattcaga gcatgaatta tctgattatt gacatccaca aaatcaatat
    29521 ggaaaccatt tttaaataga atttcaccta taaaaccacg accgatatta ccggcaccaa
    29581 aatgaacaga atgtttcatt caatttctcc ttttcctatt tgagggacat atatactaga
    29641 tgacaaatga ctaaattcaa ttattcaaca gcatcaaata agcgcaatac ttcctctttt
    29701 gactgagcat ctgctagttt aagaacatta tctacatctg cacagaagat agaaattttc
    29761 tgaataattt ctaagtgttc attaccaata ccagcaatac caaaaagaac cgttgccact
    29821 tgagggttag atacattccc aaaatcaacc cctctaggga cttgaacgac tgtaatacca
    29881 gacttgagga catcattttt tgctgcatct gttccatgcg gtatggcgat aaagttaccc
    29941 atgtaaacag atagctcttt atctcgctca atcatggctt caatatagtc ttcattaaca
    30001 tatccaccct cataaagaac ttgcccacaa taacaaatag cttcctcctt gttagaaaat
    30061 tgtttattaa gcttaatcaa atgtttttca agtttcatat tagttctcca atttcttaat
    30121 tttttcgtta aaaatagtat ttagcatctg ataaataatg gattgatttc ccgtcttgta
    30181 aatctctgta taaagatgat tttcaataat cgactgacta atagctgtca ttaaatctct
    30241 agcttcctcg ctagcttctt tagacattag cattagcaga caccttttga cctcttcttc
    30301 ctctcgtttc attgacaatg cggagatagg tagtttgagt tcaaacatag taaaactatt
    30361 tgttgttact ttgctagact gactatgtaa aagcaccaga ccagtattag gaatagccat
    30421 aggactattc tggaagtgag ataacaattt tcttgttagg taagctctgt cactcacatt
    30481 cttctgatat tggatgattt gttctaccgt gtgctcaaat gattgattat tctccaattg
    30541 aaccaactcg aattgactca aaagctgact actagatatt aaataatctt gcaagtcata
    30601 acttttctct ggagcgatag catcacgcgc gacaattgta cgatgtgcct gtacatactg
    30661 aagtcgttcc tgtaattcaa gcaattcttt gacggttgga aaactagaaa ttacatcgat
    30721 ttcctgatta gtcagcggct tggtagataa aatataatca tactgactga gatcaatact
    30781 gtggtaatct actagagatt gaatatctat caactctaca aaaggagcaa cactcttaat
    30841 tttactgact aataaatctc tagtgacccg acgttcatcc gttaaaagca aaacacggac
    30901 tggataaatc tctggactac ggcctaagct agagataaaa tgtagggcaa tcatgccata
    30961 ctcatactct gtatgaagat atttcggaaa aatatcattc actaaaagac tgatgactgt
    31021 ataaagaaat ttattccttt caactaaaat ctggatagat tctggcaaat tttcaccctg
    31081 aaaaaggata gggacgccta aactgaaccg aatatgatgg aaaagaaaat tgaataaaac
    31141 cttgtcctta aaaaagtcaa tcttggtata catggaaacc gtatcaatca gatttgaaat
    31201 attgtagaaa aattcaccat caaatttctc cgtaaagagc ggattgtcct gacgtttaat
    31261 gattaattca tccaagatgc tcgcaaaata gataatttcc tgaatactat aaaattgtgc
    31321 agtctgctta gagtaagctt gaaaaatttt ttgagaaatt tccaaagcct gcttactagt
    31381 attaggtgaa ttttcaatgt tttgctcctg acctataaga gataacaaga tcgcaaaaaa
    31441 catcttcatc ctagcatcca tatctggaaa acctgacagt tgcttattaa caatctgact
    31501 ggccagccca gttctatctg cttctaaaat atcaaagctc ccaaaattac cggttgaaaa
    31561 atctgctact gagatacagt ttgtcagtaa aatagccaaa aatcttctct taccaactga
    31621 atcaccagaa atccgataac ctttttgtcg ttcaattttc agatcaaagt ctaaaagacg
    31681 cttatcaata tctgaaatat cctgaataat agttacatta ctgactttcg tgcactcttg
    31741 caatgcttca ttggtgacaa aaccactctc agtcagaagg cgataggtaa tcaactcttg
    31801 tctttcttgg ggactatact caactaacac ttcaagttct gtcggcaaat catccaactc
    31861 tccagtcaaa atatagtatt tcccatgctt cgttatttcg attccatatt gctccatgct
    31921 atctgtcaaa tctgataaag ttcgataaat tgttctagat gaaacctgta agatttcagt
    31981 catatcttgc attgaaagct tccctacatg taggaaagcc ttcaataatt gttcttctcg
    32041 tttggttaat agcattcgta atttagaaac ctctagttct atttgtacat tctagcagcc
    32101 attttgtcat attctggtgt tgttactaaa ctatccacaa taagaaattg agaattcggt
    32161 gctgcttgct gcacttctgc ctgtaaagaa atagttgtta caatcattat gtttttagaa
    32221 ttaaattcac ctaattctga aattttggca gtagaaactg gaatacgaat attcttgttt
    32281 ctaaaaatag cccgaatcgt ttcacagccc atagttgcag ttccctgtgc tttaccataa
    32341 gcaactacta cagcatcaat atggttaagg tcactttcct gactatctac tggtgctgaa
    32401 gttggtatat ctccttcaat ttctgctatt ggagaagctc ctgttaatga agctacaatt
    32461 tcatcataac gagaggacgc taagaaatta tcaacagaaa catgaatagc acttggactc
    32521 ttgtctttag ctcttggtgt cagttcttcc tgagtaacaa ttaatgtttt tggtgtatca
    32581 agcaaatttg agattgcctg attagatact ggaatctcta gacctgcttt tttaacctta
    32641 tctcgaagaa tactagctcc catagcagag cttcccatac cagcatcgca ggcgaaaatg
    32701 attttttcca ctgagtctgt cgaaacaact gcatcaacag aagttgatac taactgacct
    32761 ttagactgag ccttagctgc ttgggtagcc gcctgagcag cttcgagcga atcctcagtt
    32821 gacttgtctg catgaagaat aagggctgct acaaggaaag aaacaactgc tgccactaaa
    32881 acacctaaaa gaacatttag atggggccaa acaccttttg gcgccgtagc tataatcgca
    32941 ataatagaac ctggtgaagc tggagattta agaccagcgt ctaagagttg aaaagtaaaa
    33001 gttccagaga tacctcctgc catagcagct aaaaatagag taggcttcat cataacataa
    33061 ggaaagtaaa tttcatgaat ccctccgaag aaatgaataa ccattgcccc ccaagaagaa
    33121 gatttagcag aacctttacc gaatacagca taagctaata gaattcccag acctggtcca
    33181 ggattagctt ccaataggaa gagaattgac ttaccagctt gagctacctg ttctactccc
    33241 agaggagtaa aaatgccatg attgagggca ttattgagga aaaggacttt agccggttcg
    33301 atgataatat tagccatagg aaggaggcga gcattgacaa tagcctcaac accattccca
    33361 acagctccag taagagtcga tacgactgga ccgattgcgt agaaagccaa aagcaataat
    33421 gcaaaaccaa cgagaccagc tgagaagtta ttaactaaca tttcaaatcc gggacgaatt
    33481 ttttcctgga acttctcatc aaatttcttg atagtccatc ctcccagtgg gcccattacc
    33541 atagctccga taaacatagg aacactagaa cctgtgattg caccaacagt agcaatagct
    33601 cctacaacgg caccacgttg gccatggatc atatatccac ctgtgtaacc aatcaggatt
    33661 ggcaataaat acgttaacat aggaccaaca acagtagcta actgttcatt tggcagatag
    33721 ccatcagcga taaagagggc agtcaatact ccccaagcaa taaatgctcc aatattgggc
    33781 ataaccatat ttgaaagcga tgtccctagt ttttgaaccc tgactttcaa tgatactttt
    33841 tcttccatta gatcatcctc cttttcttaa aactagtata tacaaagtta aaaaccttta
    33901 aaactaaagt tttgtcacag attttgtgtc aaaacattac ttttgacgag gctgggcaaa
    33961 aaggcttaaa aattataaaa cgcatcatat caggtgtaca tgaactac
//
LOCUS       DAVFER010000022        33778 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1105170250
            SAMEA2167659-rid19724873.denovo.022, whole genome shotgun sequence.
ACCESSION   DAVFER010000022 DAVFER010000000
VERSION     DAVFER010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2167659
            Sequence Read Archive: ERR388902
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 33778)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33778)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928716.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928716.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 04:07:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,118
            CDSs (total)                      :: 2,073
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 120
            CDSs (without protein)            :: 120
            Pseudo Genes (ambiguous residues) :: 0 of 120
            Pseudo Genes (frameshifted)       :: 67 of 120
            Pseudo Genes (incomplete)         :: 47 of 120
            Pseudo Genes (internal stop)      :: 34 of 120
            Pseudo Genes (multiple problems)  :: 23 of 120
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33778
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2167659-rid19724873.denovo.022"
                     /strain="1105170250"
                     /db_xref="taxon:1313"
     gene            1..1163
                     /locus_tag="VU534_001115"
                     /pseudo
     CDS             1..1163
                     /locus_tag="VU534_001115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     N-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(1291..2313)
                     /gene="cbpF"
                     /locus_tag="VU534_001116"
     CDS             complement(1291..2313)
                     /gene="cbpF"
                     /locus_tag="VU534_001116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000771060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpF"
                     /protein_id="HEU1513716.1"
                     /translation="MKLLKKMMQIALATFFFGLLATNTVFADDSEGWQFVQENGRTYY
                     KKGDLKETYWRVIDGKYYYFDPLSGEMVVGWQYIPAPHKGVTIGPSPRIEIALRPDWF
                     YFGQDGVLQEFVGKQVLEAKTATNTNKHHGEEYDSQAEKRVYYFEDQRSYHTLKTGWI
                     YEEGHWYYLQKDGGFDSRINRLTVGELARGWVKDYPLTYDEEKLKAAPWYYLNPATGI
                     MQTGWQYLGNRWYYLHSSGAMATGWYKEGSTWYYLDAENGDMRTGWQNLGNKWYYLRS
                     SGAMATGWYQESSTWYYLNASNGDMKTGWFQVNGNWYYAYDSGALAVNTTVGGYYLNY
                     NGEWVK"
     gene            complement(2332..3153)
                     /gene="cbpG"
                     /locus_tag="VU534_001117"
     CDS             complement(2332..3153)
                     /gene="cbpG"
                     /locus_tag="VU534_001117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001100143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpG"
                     /protein_id="HEU1513717.1"
                     /translation="MNVEGRGSANFIKDNVLITAAHNYYRHDYGKEADDIYVLPAVSP
                     SQEPFGKIKVKEVRYLKEFRNLNSKDAREYDLALLILEEPIGAKLGTLGLPTSQKNLT
                     GITVTITGYPSYNFKIHQMYTDKKQVLSDDGMFLDYQVDTLEGSSGSTVYDASHRVVG
                     VHTLGDGANQINSAVKLNERNLPFIYSVLKGYSLEGWKKINGSWYHYRQHDKQTGWQE
                     INDTWYYLDSSGKMLTDWQKVNGKWYYLNSNGAMVTGSQTIDGKVYNFASSGEWI"
     gene            complement(3234..3473)
                     /locus_tag="VU534_001118"
     CDS             complement(3234..3473)
                     /locus_tag="VU534_001118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000754500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1513718.1"
                     /translation="MKKTVYKKLGISIIASTLLASQLSTVSALSVISSTGEEYEVSET
                     LEKGPESNDSSLSEISPTYGSYYQKQSEVLSVMMI"
     gene            complement(3623..3889)
                     /locus_tag="VU534_001119"
                     /pseudo
     CDS             complement(3623..3889)
                     /locus_tag="VU534_001119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060522.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
     gene            complement(3914..4168)
                     /locus_tag="VU534_001120"
     CDS             complement(3914..4168)
                     /locus_tag="VU534_001120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HEU1513719.1"
                     /translation="MAANYLKAMQSYLKETDLPKLEQLVVTKSLWDTVDILDRVVGSL
                     VYEHPELEEIILILFENLFKPRQLYLQPQNSVLSNLRLAS"
     gene            complement(4150..4391)
                     /locus_tag="VU534_001121"
                     /pseudo
     CDS             complement(4150..4391)
                     /locus_tag="VU534_001121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812384.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
     gene            complement(4392..5024)
                     /locus_tag="VU534_001122"
     CDS             complement(4392..5024)
                     /locus_tag="VU534_001122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU1513720.1"
                     /translation="MKILLVDDHEMVRLGLKSYFDLQDDVEVVGEASNGSQGIDLALE
                     LRPDVIVMDIVMPEMNGIDATLAILKEWPEAKILIVTSYLDNEKIMPVLDAGAKGYML
                     KTSSADELLHAVSKVAAGELAIEQEVSKKVEYHRNHMELHEELTARERDVLQLIAKGY
                     ENQRIADDLFISLKTVKTHVSNILAKLEVSDRTQAAVYAFQHHLVGQEEF"
     gene            complement(5038..6033)
                     /locus_tag="VU534_001123"
     CDS             complement(5038..6033)
                     /locus_tag="VU534_001123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEU1513721.1"
                     /translation="MKKQAYVIIALTSFLFVFFFSHSLLEILDFDWSIFLHDVEKTEK
                     FVFLLLVFSMSMTCLLALFWRGIEELSLRKMQANLKRLLAGQEVVQVADPDLDASFKS
                     LSGKLNLLTEALQKAENQSLAQEEEIIEKERKRIARDLHDTVSQELFAAHMILSGISQ
                     QALKLDREKMQTQLQSVTAILETAQKDLRVLLLHLRPVELEQKSLIEGIQILLKELED
                     KSDLRVSLKQNMTKLPKKIEEHIFRILQELISNTLRHAQASCLDVYLYQTDVELQLKV
                     VDNGIGFQLGSLDDLSYGLRNIKERVEDMAGTVQLLTAPKQGLAVDIRIPLLDKE"
     gene            complement(6030..6728)
                     /locus_tag="VU534_001124"
     CDS             complement(6030..6728)
                     /locus_tag="VU534_001124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-active antibiotics response protein"
                     /protein_id="HEU1513722.1"
                     /translation="MRKFKIFLFIEACLLTGALILMVSEHFSRFLLILFLFLLLIRYY
                     TGKEGNNLLLVAATILFFFIVMLNPFVILAIFVAVIYSLFLLYPMMNQEKEQTNLVFE
                     EVVTVKKEKNRWFGNLHHFSSYQTCQFDDINLFRFMGKDTIHLERVILTNHDNVIILR
                     KMVGTTKIIVPVDVEVSLSVNCLYGDLIFFNQPKRALRNEHYHQETKDYLKSNKSVKI
                     FLTTMIGDVEVVRG"
     gene            complement(6805..7815)
                     /locus_tag="VU534_001125"
     CDS             complement(6805..7815)
                     /locus_tag="VU534_001125"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000210649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HEU1513723.1"
                     /translation="MTTNRKDEHILYALEQKSSYNSFDEVELIHSSLPLYNLDEIDLS
                     TEFAGRKWDFPFYINAMTGGSNKGREINQKLAQVAESCGILFVTGSYSAALKNPTDDS
                     FSVKSSHPNLLLGTNIGLDKPVELGLQTVEEMNPVLLQVHVNVMQELLMPEGERKFRS
                     WQSHLADYSKQIPVPIVLKEVGFGMDAKTIERAYEFGVRTVDLSGRGGTSFAYIENRR
                     SGQRDYLNQWGQSTMQALLNAQEWKDKVELLVSGGVRNPLDMIKCLVFGAKAVGLSRT
                     VLELVETYTVEEVIGIVQGWKADLRLIMCSLNCATIADLQKVDYLLYGKLKEAKDQMK
                     KA"
     gene            complement(7799..8806)
                     /locus_tag="VU534_001126"
     CDS             complement(7799..8806)
                     /locus_tag="VU534_001126"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000562378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HEU1513724.1"
                     /translation="MIAVKTCGKLYWAGEYAILEPGQLALIKDIPIYMRAEIAFSDSY
                     RIYSDMFDFAVDLRPNPDYSLIQETIALMGDFLAVRGQNLRPFSLEICGKMEREGKKF
                     GLGSSGSVVVLVVKALLALYDVSVDQELLFKLTSAVLLKRGDNGSMGDLACIVAEDLV
                     LYQSFDRQKVAAWLEEENLATVLERDWGFSISQVKPTLECDFLVGWTKEVAVSSHMVQ
                     QIKQNINQNFLTSSKETVTSLVEALEQGKSEKIIDQVEVASKLLEGLSTDIYTPLLRQ
                     LKEASQDLQTVAKSSGAGGGDCGIALSFDAQSTKTLKNRWADLGIELLYQERIGHDDK
                     S"
     gene            complement(8793..9746)
                     /gene="mvaD"
                     /locus_tag="VU534_001127"
     CDS             complement(8793..9746)
                     /gene="mvaD"
                     /locus_tag="VU534_001127"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000373478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HEU1513725.1"
                     /translation="MDREPVTVRSYANIAIIKYWGKKKEKEMVPATSSISLTLENMYT
                     ETTLSPLPANVTADEFYINGQLQNEVEHAKMSKIIDRYRPAGEGFVRIDTQNNMPTAA
                     GLSSSSSGLSALVKACNAYFKLGLDRSQLAQEAKFASGSSSRSFYGPLGAWDKDSGEI
                     YPVETDLKLAMIMLVLEDKKKPISSRDGMKLCVETSTTFDDWVRQSEKDYQDMLIYLK
                     ENDFAKIGELTEKNALAMHATTKTASPAFSYLTDASYEAMAFVRQLREKGEACYFTMD
                     AGPNVKVFCQEKDLEHLSEIFGHRYRLIVSKTKDLSQDDCC"
     gene            complement(9728..10606)
                     /gene="mvk"
                     /locus_tag="VU534_001128"
     CDS             complement(9728..10606)
                     /gene="mvk"
                     /locus_tag="VU534_001128"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HEU1513726.1"
                     /translation="MTKKVGVGQAHSKIILIGEHAVVYGYPAISLPLLEVEVTCKVVP
                     AESPWRLYEEDTLSMAVYASLEYLNITEACIRCEIDSAIPEKRGMGSSAAISIAAIRA
                     VFDYYQADLPHDVLEILVNRAEMIAHMNPSGLDAKTCLSDQPIRFIKNVGFTELEMDL
                     SAYLVIADTGVYGHTREAIQVVQNKGKDALPFLHALGELTQQAEVAISQKDAEGLGQI
                     LSQAHLHLKEIGVSSPEADFLVETTLSHGALGAKMSGGGLGGCIIALVTNLTHAQELA
                     ERLEEKGAVQTWIESL"
     gene            complement(10781..11059)
                     /locus_tag="VU534_001129"
     CDS             complement(10781..11059)
                     /locus_tag="VU534_001129"
                     /inference="COORDINATES: protein motif:HMM:NF024736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU1513727.1"
                     /translation="MIRKAYDTDLNDQEWAKIEPYFSKHRTYKWPKRVLVNETLYVTK
                     TGCQWRMLPHDFPLYLMVWSFFRRSMTTGWFQVNGRWYYAYSAQVPWQ"
     gene            11584..12546
                     /locus_tag="VU534_001130"
     CDS             11584..12546
                     /locus_tag="VU534_001130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001817814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lanthionine synthetase"
                     /protein_id="HEU1513728.1"
                     /translation="MTSSTEFGNFVSNLSFQHGIAGLLFPLNKLYPPELDSKILSIIK
                     KAVTIRTTHTYEYQYSLLFGDAGYLWLLLHLFSISKNQYYLQLANVTAKKLIENYDTL
                     EEIDFALGKSGVLLSLIKYYQFTNDNTLKIFIHNSIGEIYHYFLQRDTAKESILDYSF
                     AHGYCGIAYALFAYSKVLEPSMFYNDLHTFHTELKKLLEKVTSNTENLGNLQLSWCKG
                     ISGIILYLCMYDCDGNKDIISKYQEFVFNHHLKMMTGYCHGITSLLQTTVYNQNKLLM
                     KKIQQVILACSERDDHGLLMFQGDSGKADLFDFGIGSMGYIGVY"
     gene            12589..13821
                     /locus_tag="VU534_001131"
     CDS             12589..13821
                     /locus_tag="VU534_001131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000765682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEU1513729.1"
                     /translation="MKLFWTNNIYRQLLLNSCFSSFGDSIFYLAIINYVAQYNFAPLA
                     ILLISISEMVPLLSQLFLGILGDFQENRVKHALWIAKIKILLYAILTVFLVLSPFSLV
                     SVIMIVIINLISDTLSYLSAYMMNALYISVIKDDLHDAMGFRQSLMRVVRIVANLAGA
                     FLINVISIQTISLINTLTFVIAFLGLYVIRHTLYEVEKRIEMSHTALSFKKYFQHLKQ
                     SLAVLLRLKDTVILLFLTTSMIAILDVSPRLIALRFIQQTLAQLSIGQLLALLSIIMS
                     CGAILGNMTSSNLFKNIRFTHLLVFCEISLLTLITSILCQAYIVIFMTSFISSTIIGI
                     LSPRLQAAVFAHIPSDKMGTVGSALSTVDILAPSLLSLLALSIASGVSVQLALIFLYL
                     ILIALIFCQWLVKFNTHN"
     gene            complement(13939..14937)
                     /gene="cbpJ"
                     /locus_tag="VU534_001132"
     CDS             complement(13939..14937)
                     /gene="cbpJ"
                     /locus_tag="VU534_001132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpJ"
                     /protein_id="HEU1513730.1"
                     /translation="MKILKKTMQVGLTVFFFGLLGTSTVFADDSEGWQFVQENGRTYY
                     KKGDLKETYWRVIDGKYYYFDSLSGEMVVGWQYIPFPSKGSTIGPYPNGIRLEGFPKS
                     EWYYFDKNGVLQEFVGWKTLEIKTKDSVGRKYGEKREDSEDKEEKRYYTNYYFNQNHS
                     LETGWLYDQSNWYYLAKTEINGENYLGGERRAGWINDDSTWYYLDPTTGIMQTGWQYL
                     GNKWYYLRSSGAMATGWYQEGTTWYYLDHPNGDMKTGWQNLGNKWYYLRSSGAMATGW
                     YQDGSTWYYLNAGNGDMKTGWFQVNGNWYYAYSSGALAVNTTVDGYSVNYNGEWVR"
     gene            complement(14955..15977)
                     /gene="cbpC"
                     /locus_tag="VU534_001133"
     CDS             complement(14955..15977)
                     /gene="cbpC"
                     /locus_tag="VU534_001133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000771084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpC"
                     /protein_id="HEU1513731.1"
                     /translation="MKLLKKMMQVALAVFFFGLLATNTVFANTTGGRFVDKDNRKYYV
                     KDDHKAIYWHKIDGKTYYFGDIGEMVVGWQYLEIPGTGYRDNLFDNQPVNEIGLQEKW
                     YYFGQDGALLEQTDKQVLEAKTSENTGKVYGEQYPLSAEKRTYYFDNNYAVKTGWIYE
                     EGHWYYLNKLGNFGDDSYNPLPIGEVAKGWTQDFHVTIDIDRSKPAPWYYLDASGKML
                     TDWQKVNGKWYYFGSSGSMATGWKYVRGKWYYLDNKNGDMKTGWQYLGNKWYYLRSSG
                     AMVTGWYQDGSTWYYLDPSNGDMKIGWTKVNGKWYYLNSNGAMVTGSQTIDGKVYNFA
                     SSGEWI"
     gene            complement(16076..16765)
                     /locus_tag="VU534_001134"
     CDS             complement(16076..16765)
                     /locus_tag="VU534_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000518023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU1513732.1"
                     /translation="MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQ
                     TDYDLMLLNVNLGDMMAQDFAEKLSRTKPASVIMILDHWEDLQEELEVVQRFAVSYIY
                     KPVLIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
                     REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIK
                     TVRGVGYTMQE"
     gene            complement(16777..18201)
                     /gene="gndA"
                     /locus_tag="VU534_001135"
     CDS             complement(16777..18201)
                     /gene="gndA"
                     /locus_tag="VU534_001135"
                     /EC_number="1.1.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004185725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent phosphogluconate dehydrogenase"
                     /protein_id="HEU1513733.1"
                     /translation="MTKANFGVVGMAVMGRNLALNIESRGYTVAIYNRSKEKTEDVIA
                     CHPEKNFVPSYDVESFVNSIEKPRRIMLMVQAGPGTDATIQALLPHLDKGDILIDGGN
                     TFYKDTIRRNEELANSGINFIGTGVSGGEKGALEGPSIMPGGQKEAYELVADVLEEIS
                     AKAPEDGKPCVTYIGPDGAGHYVKMVHNGIEYGDMQLIAESYDLMQHLLGLSAEDMAE
                     IFTEWNKGELDSYLIEITADILSRKDDEGQDGPIVDYILDAAGNKGTGKWTSQSSLDL
                     GVPLSLITESVFARYISTYKEERVHASKVLPKPAAFNFEGDKAELIEKIRQALYFSKI
                     ISYAQGFAQLRVASKENNWNLPFADIASIWRDGCIIRSRFLQKITDAYNRDADLANLL
                     LDEYFLDVTAKYQQAVRDIVALAVQAGVPVPTFSAAITYFDSYRSADLPANLIQAQRD
                     YFGAHTYQRKDKEGTFHYSWYDEK"
     gene            complement(18277..19671)
                     /gene="mapZ"
                     /locus_tag="VU534_001136"
     CDS             complement(18277..19671)
                     /gene="mapZ"
                     /locus_tag="VU534_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000039255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mid-cell-anchored protein MapZ"
                     /protein_id="HEU1513734.1"
                     /translation="MSKKRRNRHKKEGQEPQFDFDEAKELTVGQAIRKNEEVESGVLP
                     EDSILDKYVKQHRDEIEADKFATRQYKKEEFVETQSLDDLIQEMREAVEKSEASSEEV
                     PSSEDILLPLPLDDEEQGLDPLLLDDENPTEMTEEVEEEQNLSRLDQEDSEKKSKKGF
                     ILTVLALVSVIICVSAYYVYRQVARSTKEIETSQSTTANQSDVDDFNTLYDAFYTDSN
                     KTALKNSQFDKLSQLKTLLDKLEGSREHTLAKSKYDSLATQIKAIQDVNAQFEKPAIV
                     DGVLDTNAKAKSDAKFTDIKTGNTELDKVLDKAISLGKSQQTSTSSSSSSQTSSSSSS
                     QASSNTTSEPKPSSSNETRSSRSEVNMGLSSAGVAVQRSASRVAYNQSAIDDSNNSAW
                     DFADGVLEQILATSRSRGYITGDQYILERVNIVNGNGYYNLYKPDGTYLFTLNCKTGY
                     FVGNGAGHADDLDY"
     gene            complement(19684..20841)
                     /locus_tag="VU534_001137"
     CDS             complement(19684..20841)
                     /locus_tag="VU534_001137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HEU1513735.1"
                     /translation="MKKEFNLIATVAAGLEAVVGREVRELGYDCQVENGRVRFQGDVR
                     AIIETNLWLRAADRIKIIVGTFPAKTFEELFQGVFALDWENYLPLGARFPISKAKCVK
                     SKLHNEPSVQAISKKAVVKKLQKHYARPEGVPLMENGPEFKIEVSILKDVATVMIDTT
                     GSSLFKRGYRTEKGGAPIKENMAAAILQLSNWYPDKPLIDPTCGSGTFCIEAVMIARK
                     MAPGLRRSFAFEEWNWISDRLIQEVRTEAAKKVDRELELDIMGCDIDARMVEIAKANA
                     QVAGVAGDITFKQMRVQDLRSDKINGVIISNPPYGERLSDDAGVTKLYAEMGQVFAPL
                     KTWSKFILTSDEAFESKYGSQADKKRKLYNGTLKVDLYQYFGQRVKRQEVK"
     gene            complement(20926..21306)
                     /gene="rnpB"
                     /locus_tag="VU534_001138"
     ncRNA           complement(20926..21306)
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="VU534_001138"
                     /product="RNase P RNA component class B"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00011"
     gene            complement(21327..21656)
                     /gene="gpsB"
                     /locus_tag="VU534_001139"
     CDS             complement(21327..21656)
                     /gene="gpsB"
                     /locus_tag="VU534_001139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000146522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division regulator GpsB"
                     /protein_id="HEU1513736.1"
                     /translation="MASIIFSAKDIFEQEFGREVRGYNKVEVDEFLDDVIKDYETYAA
                     LVKSLRQEIADLKEELTRKPKPSPVQAEPLEAAITSSMTNFDILKRLNRLEKEVFGKQ
                     ILDNSDF"
     gene            complement(21726..22253)
                     /locus_tag="VU534_001140"
     CDS             complement(21726..22253)
                     /locus_tag="VU534_001140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1273 domain-containing protein"
                     /protein_id="HEU1513737.1"
                     /translation="MATALVLGYSAFDLGLFSDKDPRLKLIKKAIRKDLEAMAADGVS
                     WLVFTGSLGFEYWVLEVAQEMKTEYGFQLATIFAFETHGENWNEGNQMKLSRFKQVDF
                     VKYAYPRYEHKGQLRDYQQFLLENTTSSYLFYDEENETKLAYFYQKMKNQEDYFIKRL
                     TFDELNELAENFSEN"
     gene            22319..22915
                     /gene="recU"
                     /locus_tag="VU534_001141"
     CDS             22319..22915
                     /gene="recU"
                     /locus_tag="VU534_001141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HEU1513738.1"
                     /translation="MVNYPHKVSSQKRQTSLSQPKNFANRGMSFEKMINATNDYYLSQ
                     GLAVIHKKPTPIQIVQVDYPQRSRAKIVEAYFRQASTTDYSGVYNGYYIDFEVKETKQ
                     KRAIPMKNFHPHQIQHMEQVLAQQGICFVLLHFSSQQETYLLPAFDLIRFYHQDKGQK
                     SMPLEYIREYGYEIKAGAFPQIPYLNVIKEHLLGGKTR"
     gene            22912..25071
                     /locus_tag="VU534_001142"
     CDS             22912..25071
                     /locus_tag="VU534_001142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001040003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 1A"
                     /protein_id="HEU1513739.1"
                     /translation="MNKPTILRLIKYLSISFLSLVIAAIVLGGGVFFYYVSKAPSLSE
                     SKLVATTSSKIYDNKNQLIADLGSERRVNAQANDIPTDLVKAIVSIEDHRFFDHRGID
                     TIRILGAFLRNLQSNSLQGGSTLTQQLIKLTYFSTSTSDQTISRKAQEAWLAIQLEQK
                     ATKQEILTYYINKVYMSNGNYGMQTAAQNYYGKDLNNLSLPQLALLAGMPQAPNQYDP
                     YSHPEAAQDRRNLVLSEMKNQGYISAEQYEKAVNTPITDGLQSLKSASNYPAYMDNYL
                     KEVINQVEEETGYNLLTTGMDVYTNVDQEAQKHLWDIYNTDEYVAYPDDELQVASTIV
                     DVSNGKVIAQLGARHQSSNVSFGINQAVETNRDWGSTMKPITDYAPALEYGVYDSTAT
                     IVHDEPYNYPGTNTPVYNWDRGYFGNITLQYALQQSRNVPAVETLNKVGLNRAKTFLN
                     GLGIDYPSIHYSNAISSNTTESDKKYGASSEKMAAAYAAFANGGTYYKPMYIHKVVFS
                     DGSEKEFSNVGTRAMKETTAYMMTDMMKTVLTYGTGRNAYLAWLPQAGKTGTSNYTDE
                     EIENHIKTSQFVAPDELFAGYTRKYSMAVWTGYSNRLTPLVGNGLTVAAKVYRSMMTY
                     LSEGSNPEDWNIPEGLYRNGEFVFKNGARSTWNSPAPQQPPSTESSSSSSDSSTSQSS
                     STTPSTNNSTTTNPNNNTQQSNTTPDQQNQNPQPAQP"
     gene            complement(25238..30541)
                     /locus_tag="VU534_001143"
     CDS             complement(25238..30541)
                     /locus_tag="VU534_001143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001032503.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HEU1513740.1"
                     /translation="MNKGLFEKRCKYSIRKFSLGVASVMIGAAFFGTSPVLADSVQSG
                     STANLPADLATALATAKENDGRDFEAPKVGEDQGSPEVTDGPKTEEELLALEKEKPAE
                     EKPKEDKPAAAKPETPKTVTPEWQTVANKEQQGTVTIREEKGVRYNQLSSTAQNDNAG
                     KPALFEKKGLTVDANGNATVDLTFKDDSEKGKSRFGVFLKFKDTKNNVFVGYDKDGWF
                     WEYKSPTTSTWYRGSRVAAPETGSTNRLSITLKSDGQLNASNNDVNLFDTVTLPAAVN
                     DHLKNEKKILLKAGSYDDERTVVSVKTDNQEGVKTEDTPAEKETGPEVDDSKVTYDTI
                     QSKVLKAVIDQAFPRVKEYSLNGHTLPGQVQQFNQVFINNHRITPEVTYKKINETTAE
                     YLMKLRDDAHLINAEMTVRLQVVDNQLHFDVTKIVNHNQVTPGQKIDDESKLLSSISF
                     LGNALVSVSSNQTGAKFDGATMSNNTHVSGDDHIDVTNPMKDLAKGYMYGFVSTDKLA
                     AGVWSNSQNSYGGGSNDWTRLTAYKETVGNANYVGIHSSEWQWEKAYKGIVFPEYTKE
                     LPSAKVVITEDANADKNVDWQDGAIAYRSIMNNPQGWEKVKDITAYRIAMNFGSQAQN
                     PFLMTLDGIKKINLHTDGLGQGVLLKGYGSEGHDSGHLNYADIGKRIGGVEDFKTLIE
                     KAKKYGAHLGIHVNASETYPESKYFNEKILRKNPDGSYSYGWNWLDQGINIDAAYDLA
                     HGRLARWEDLKKKLGDGLDFIYVDVWGNGQSGDNGAWATHVLAKEINKQGWRFAIEWG
                     HGGEYDSTFHHWAADLTYGGYTNKGINSAITRFIRNHQKDAWVGDYRSYGGAANYPLL
                     GGYSMKDFEGWQGRSDYNGYVTNLFAHDVMTKYFQHFTVSKWENGTPVTMTDNGSTYK
                     WTPEMRVELVDADNNKVVVTRKSNDVNSPQYRERTVTLNGRVIQDGSAYLTPWNWDAN
                     GKKLSTDKEKMYYFNTQAGATTWTLPSDWAKSKVYLYKLTDQGKTEEQELTVKDGKIT
                     LDLLANQPYVLYRSKQTNPEMSWSEGMHIYDQGFNSGTLKHWTISGDASKAEIVKSQG
                     ANDMLRIQGNKEKVSLTQKLTGLKPNTKYAVYVGVDNRSNAKASITVNTGEKEVTTYT
                     NKSLALNYVKAYAHNTRRDNATVDDTSYFQNMYAFFTTGADVSNVTLTLSREAGDQAT
                     YFDEIRTFENNSSMYGDKHDTGKGTFKQDFENVAQGIFPFVVGGVEGVEDNRTHLSEK
                     HNPYTQRGWNGKKVDDVIEGNWSLKTNGLVSRRNLVYQTIPQNFRFEAGKTYRVTFEY
                     EAGSDNTYAFVVGKGEFQSGRRGTQASNLEMHELPNTWTDSKKAKKATFLVTGAETGD
                     TWVGIYSTGNASNTRGDSGGNANFRGYNDFMMDNLQIEEITLTGKMLTENALKNYLPT
                     VAMTNYTKESMDALKEAVFNLSQADDDISVEEARAEIAKIEALKNALVQKKTALVADD
                     FASLTAPAQAQEGLANAFDGNVSSLWHTSWNGGDVGKPATMVLKEPTEITGLRYVPRG
                     SGSNGNLRDVKLVVTDESGKEHTFTATDWPNNNKPKDIDFGKTIKAKKIVLTGTKTYG
                     DGGDKYQSAAELIFTRPQVAETPLDLSGYEAALVKAQKLTDKDNQEEVASVQASMKYA
                     TDNHLLTERMVEYFADYLNQLKDSATKPDAPTVEKPEFKLRSLASEQGKTPDYKQEIA
                     RPETPEQILPATGESQSDTALILASVSLALSALFVVKTKKD"
     gene            complement(30843..32825)
                     /locus_tag="VU534_001144"
     CDS             complement(30843..32825)
                     /locus_tag="VU534_001144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEU1513741.1"
                     /translation="MKSSKLFALAGVTLLAATTLAACSGSGSSTKGEKTFSYIYETDP
                     DNLNYLTTAKAATANITSNVVDGLLENDRYGNFVPSMAEDWSVSKDGLTYTYTIRKDA
                     KWYTSEGEEYAAVKAQDFVTGLKYAADKKSDALYLVQESIKGLDAYVKGEIKDFSQVG
                     IKALDEQTVQYTLNKPESFWNSKTTMGVLAPVNEEFLNSKGDDFAKATDPSSLLYNGP
                     YLLKSIVTKSSVEFAKNPNYWDKDNVHVDKVKLSFWDGQDTSKPAENFKDGSLTAARL
                     YPTSASFAELEKSMKDNIVYTQQDSITYLVGTNIDRQSYKYTSKTSDEQKASTKKALL
                     NKDFRQAIAFGFDRTAYASQLNGQTGASKILRNLFVPPTFVQADGKNFGDMVKEKLVT
                     YGDEWKDVNLADSQDGLYNPEKAKAEFAKAKSALQAEGVQFPIHLDMPVDQTATTKVQ
                     RVQSMKQSLEATLGADNVIIDIQQLQKDEVNNITYFAENAAGEDWDLSDNVGWGPDFA
                     DPSTYLDIIKPSVGESTKTYLGFDSGEDNVAAKKVGLYDYEKLVTEAGDETTDVAKRY
                     DKYAAAQAWLTDSALIIPTTSRTGRPILSKMVPFTIPFALSGNKGTSEPVLYKYLELQ
                     DKAVTVDEYQKAQEKWMKEKEESNKKAQEDLAKHVK"
     gene            33030..33215
                     /locus_tag="VU534_001145"
     CDS             33030..33215
                     /locus_tag="VU534_001145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001136123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1513742.1"
                     /translation="MPQPIVPVEIPQSRRFDSKKRNDILLKIRIGKLEVSFFQSLNLE
                     MIEQLLDKVLLYDNSSI"
     gene            33196..33519
                     /gene="tnpB"
                     /locus_tag="VU534_001146"
     CDS             33196..33519
                     /gene="tnpB"
                     /locus_tag="VU534_001146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HEU1513743.1"
                     /translation="MTIHLSSLGQVYLVCGKTDMRQGIDSLAYLVKTHFELDPFSGQI
                     FLFCGGRKDRFKVLYWDGQGFWLLYKRFENGRLTWPSTEKDVKALAPEQVDWLMKGFS
                     ITPKI"
BASE COUNT         9778 a         7606 c         6019 g        10375 t
ORIGIN      
        1 ctgatttaaa acaagaaatg agtaataaag tctgacatga aggctggact aaagatagag
       61 tttctcttga atacggtctc ccaagtcgta cgatacttct taactggcta gcacaataca
      121 ggaaaaacgg gtatactatt gttgagaaaa caagagggag agtacctaaa atgggacgta
      181 agccaaaaac gagacctgaa gagaggacag aattagaacg tcttcaagca gaaaatgagt
      241 acctgagagc ggagaatgcc atcctaaaaa agttaagaga actccgattg aaggaggaga
      301 aagaagaaag acagaaattg ttcaagaatt aatgactgaa ttttcgttag ctcttcttct
      361 aaaagtcatt aaactagctc gttcgaccta ctactatcac ttgaaacagc tagataaacc
      421 agataaggac taagagctta aagctgaaat tcaatccatt tttatcgaac acaagggaaa
      481 ttatacttat cgccgggttc atttagaact aagaaatcgt ggttatctgg taaatcataa
      541 aagaattcaa ggcttgatga aagtactcaa tttacaagct aaaacgcgac agaaacgaaa
      601 atattcttct cataaaagac gttggcaaga aggcagagaa tctcattcaa ggccaatttg
      661 aaggctctaa aacaatggaa aagtgctaca cagatgtgac agaatttgcc attccagcaa
      721 gtactcaaaa gctttactta tcaccagttt tagatggctt taatagcgaa attatcgcct
      781 ataatctttc aacttcaccc aacttagaac aagtacaaac aatgttggaa caggcattca
      841 cagagaagca ctacgagaat acgattctcc atagtgacca aggctggcaa taccaacacg
      901 attcttatca tcgattccta gagagtaagg gaattcaagc atccatgtca cgtaagggaa
      961 acagcccaga caatagtatg atggagtcct tctttgggat tctgaaatcg gaaatgtttt
     1021 acggttatga gaagtcgttt cagtcgctta agcaattgga acaagccatt atagactata
     1081 ttgattacta caacaataaa cgaattaagg taaaactaaa aggacttagc cctgtgcaat
     1141 acagaactaa atccttcgga taaattaatt gtctaactgt ttgagggcag tacagaaaaa
     1201 ccttgatact atgcgttttt tgattgtgaa gacttttatc cacctattat acaaagttaa
     1261 gtatccatca cagtttacaa ttagccttca ttacttaacc cattcaccat tatagtttaa
     1321 gtagtaacca cctactgtgg tattaacagc taaagcacct gaatcatagg catagtacca
     1381 gttaccattg acttggaacc agcctgtttt catatctcca ttacttgcat ttagatagta
     1441 ccaagtcgaa ctttcctgat accaaccagt tgccatagct cctgatgaac ggagatagta
     1501 ccatttgttc ccaaggtttt gccagccagt tctcatatca ccattttcag catctagata
     1561 gtaccaagtt gagccttcct tataccagcc agttgccata gctcctgacg aatggaggta
     1621 gtaccatcta ttacctagat attgccaacc tgtttgcata atgccagttg ctggatttag
     1681 atagtaccat ggagctgctt ttagcttctc ttcatcatac gtaagagggt aatccttaac
     1741 ccaaccacgt gctagctctc caaccgtcaa tctgttgatg cgcgaatcaa agccaccatc
     1801 cttctgtaaa taataccaat gaccctcttc ataaatccaa ccagttttta aagtatgata
     1861 actacgctga tcttcaaaat aatagactcg tttctctgct tggctatcat attcttcccc
     1921 atgatgtttg ttggtattcg tagcagtttt tgcttctaaa acttgcttgc caacaaattc
     1981 ttgtaataca ccatcttgac caaaataaaa ccaatctggt ctaagagcaa tctctattct
     2041 tggagaagga ccaatcgtaa cccccttgtg tggagcaggt atatattgcc agccgacaac
     2101 catctctccg gataaaggat caaaataata gtacttccca tctatcactc tccagtaggt
     2161 ttcttttaga tccccctttt tgtagtaggt tctaccattt tcttggacaa actgccatcc
     2221 ttcagaatca tctgcaaata ctgtatttgt cgctaacaaa ccgaagaaaa atgtggctag
     2281 tgcgatttgc atcatttttt tcaaaagctt cattttatat atcctccaac attaaatcca
     2341 ctcaccagat gaagcgaagt tataaacttt accatcgata gtttggctac ctgtaaccat
     2401 tgctccattt gaattgagat aataccattt tccatttact ttttgccaat ctgtaagcat
     2461 cttaccggaa ctgtctaaat aataccaagt atcatttatc tcctgccaac ccgtttgttt
     2521 atcatgttgt ctataatggt accaactacc atttattttc ttccatcctt caagagagta
     2581 acctttaaga accgaataaa taaatggcaa atttcgttca tttaatttaa ctgcactgtt
     2641 aatttgatta gctccatctc ctaaagtatg cactcctact acacggtgac tagcatcata
     2701 aactgtagat ccactagacc cctctaaagt atcaacttgg taatccaaga acatgccatc
     2761 atcacttaaa acttgttttt tatctgtata catttgatga attttaaaat tatatgatgg
     2821 atagcctgtg atagtcacag ttattcctgt caaatttttt tgactagtag gaagacccaa
     2881 agtccctaat tttgcaccaa tgggctcttc tagaattaat aaagccaagt catattccct
     2941 tgcatcctta gaatttaaat ttctaaattc cttcaaataa cgaacttcct ttactttgat
     3001 ctttccaaat ggttcttgac ttggactaac agccggaaga acataaatat catccgcttc
     3061 tttcccatag tcatgtctgt agtagttgtg agccgctgta attaacacat tatctttaat
     3121 aaaattcgca cttcccctcc cttctacatt cattccatcg gctactccat aatacttaga
     3181 taaaaccata gctgaagtcg aatacggata ctgtaaagta ttatcaattt taatcaaatc
     3241 atcattaccg ataatacttc tgattgcttt tggtagtatg aaccatacgt tggtgaaatc
     3301 tcagataatg aagaatcatt agactctgga cctttttcta gtgtctcact tacctcatat
     3361 tcttcacctg tactagaaat aacactcaaa gcagatactg tcgataactg gctagccaat
     3421 aaagtactcg caataattga aatacccaat tttttataaa cagttttctt cattattgta
     3481 tcctcctaat gtaattatag cgtactattc taaatttctt aatctactat agaatcaaga
     3541 aatctaccac cttctttaaa taccctccat tatcacataa acaggtaaac ttttcaatta
     3601 atgactgcgc ttttcaatca cgctagaggt acttgcttgc ttctttgata ctaagttcag
     3661 ccattctttc cttgtttttc tcaataaagc atgttaccca agtgggattc gttttggagt
     3721 agtctcgcag agtccagcca atggctttat tgataaaaaa ttctgtttgg ttcaagttat
     3781 gaaggagaat cttttccatt aattgagtat tggtcttctc ttttcttaac aactggtggt
     3841 caatagcgac acgtctcagc cagatattat ctgataggct ccattttata ctcaatgaaa
     3901 atcaaagagc aaactaggaa gctagccgca ggttgctcaa aacactgttt tgaggttgca
     3961 gatagagctg acgtggtttg aagagatttt cgaagagtat taagattatt tcttctagtt
     4021 cagggtgttc atacaccaaa ctccctacta ctcgatctag gatatctacc gtgtcccaca
     4081 aggattttgt cacgactaac tgctctagct taggcaaatc ggtttccttt agataagact
     4141 gcattgcttt caaatagtta gcagccacat attggtattt tctaggatcc ttttcccagc
     4201 aagtgtctgc aaaatcccaa tcgataatct ttgttttttt cgcttctgga aaatatttta
     4261 tagagtttat ttctttcagg caccgcaata cctagaaaag aaaattgatg gcgcatatag
     4321 gcttccatgg accttgcttt tttagagtct tttgctgctt ctagctcctc aagtaaatct
     4381 gctaaactca tctaaaactc ctcttgcccc accaaatggt gctgaaaggc atagacagcc
     4441 gcctgggtac gatcgctgac ttcaagtttg gcaagaatat tggacacgtg ggtcttgacc
     4501 gtcttgagag agataaagag gtcatctgcg atgcgctgat tttcgtagcc cttggcgatg
     4561 agttggagaa catctcgctc acgcgcagtc aattcttcat gaagttccat atgattgcgg
     4621 tggtattcaa ccttcttgct aacctcttgc tcaatggcca gctcgccagc agctacctta
     4681 ctgacggcat gaagcaattc atctgcacta gaagtcttga gcatatagcc tttggcacca
     4741 gcatctaaga ctggcatgat tttttcattg tccaaataag aggtcacaat caaaatcttg
     4801 gcttcaggcc attctttaag gattgctaag gtcgcgtcaa tcccattcat ctcaggcatg
     4861 acaatatcca tgacaatgac atctggacgc agttccaagg ccaagtcaat cccttgagac
     4921 ccgttggacg cctcacccac aacttctaca tcgtcttgga ggtcaaagta gcttttcaag
     4981 cccaatcgga ccatttcatg gtcatctact agtaaaattt tcatctttac tcctttatca
     5041 ttccttatct aacaggggaa tacggatatc aaccgccagc ccttgcttgg gagctgtcaa
     5101 gagttgaact gttccagcca tatcttcaac ccgctccttg atatttcgca gtccataact
     5161 caagtcgtct aagctcccta actggaaacc aatcccattg tccaccacct tcagttgcaa
     5221 ttcaacatct gtctgataga ggtagacatc taggcaagat gcctgggcat ggcggagggt
     5281 attgctaatc aactcttgca ggatacggaa gatatgctcc tcgattttct taggcaattt
     5341 cgtcatattc tgcttgagac taaccctaag atcactcttg tcctcaagct cttttaaaag
     5401 aatttgaatc ccttctatca agctcttctg ctccagttca actggtcgca aatgcaagag
     5461 caaaacccgc aaatccttct gggctgtttc taaaatagct gtgacactct gcaactgggt
     5521 ctgcatcttt tctctatcca atttcaaagc ctgctgactg atacccgata aaatcatgtg
     5581 ggccgcaaac aactcctgac tgactgtatc gtgcaaatcc cgagcaattc gcttccgttc
     5641 cttctcgatg atttcctctt cctgagcaag gctctgattt tcagcttttt gaagagcctc
     5701 tgtcaaaagg ttaagtttac ctgataagga cttgaaactg gcatccaaat ctggatctgc
     5761 aacctgaacc acttcttgcc ctgctaataa acgcttgaga ttagcctgca tttttcttag
     5821 agaaagctct tcgatccctc gccaaaacag ggctaagaga caggtcatgg acatgctgaa
     5881 aaccaacaat aaaaagacaa atttttctgt tttttcgaca tcgtgcaaaa agatagacca
     5941 gtcaaaatca agtatttcca gcaagctgtg ggagaaaaaa aagacaaata ggaaggaggt
     6001 gagagcaata atgacatagg cttgtttttt catcctctaa ccacctccac atcaccaatc
     6061 atagtggtca agaaaatctt gacactcttg ttactcttga gatagtcttt tgtttcttga
     6121 tgatagtgtt cattgcggag ggctcgcttg ggctggttga aaaaaatcaa atccccatag
     6181 agacagttaa cgctgagact gacttccaca tctacaggta cgatgatttt ggtcgttcct
     6241 accatctttc tgaggataat gacattgtca tgattggtta agatgaccct ctccagatga
     6301 atagtgtcct tgcccatgaa gcgaaagaga ttgatatcat cgaattggca agtctggtag
     6361 cttgaaaaat gatgaagatt tccaaaccaa cgatttttct ccttcttaac cgtcacgacc
     6421 tcttcaaaaa ccaaattggt ctgctctttt tcctggttca tcatcgggta aagaagaaag
     6481 aggctataga taaccgcaac aaaaatagct agaatcacaa aaggattgag cataacgatg
     6541 aaaaagaaga gaatggttgc cgctactaaa agaagattat ttccctcttt accagtgtag
     6601 tagcgaatca aaagcaaaaa gaggaatagt atcagcagaa aacgcgaaaa atgctctgat
     6661 accatcaaaa tcagagctcc tgtcagaaga caggcttcga taaataaaaa gattttaaat
     6721 tttctcatag gttcatcctc tcccttctat tttatcacaa ttcaaaaaag tcacctcagt
     6781 ctgaggatgg aaaaaaggcg ctggttacgc ctttttcatc tgatcctttg cttcttttaa
     6841 ttttccataa agaagatagt ctactttttg tagatctgct atggtggcac agttaaggga
     6901 acacataatc aagcgtagat ctgctttcca gccttggaca atgccaatca cttcttcaac
     6961 tgtgtaggtt tcaaccaatt ccagaacggt tcgtgacaat cccacagcct tagcaccaaa
     7021 aaccaagcac ttaatcatat ccagcggatt ccgaacccct ccactaacca agagttcgac
     7081 cttatctttc cattcttggg cattgagaag ggcctgcatg gtagactgac cccattgatt
     7141 gaggtaatca cgctggccac tacgacggtt ttcgatatag gcaaagctgg tgccaccacg
     7201 acccgatagg tccactgtac gaacaccgaa ttcataggct ctttcgattg tcttggcatc
     7261 cattccaaag cccacttcct tgaggacaat aggaacggga atttgcttgc tataatctgc
     7321 tagatgcgat tgccagcttc taaacttcct ttctccctcg ggcatgagta attcctgcat
     7381 gacattgaca tgcacttgca atagaacagg attcatctct tctacagtct gaagtcctaa
     7441 ctcgacaggc ttgtccaatc caatattggt tccaaggagg agattgggat gactagactt
     7501 gacagaaaaa gaatcatccg ttggattttt gagggctgcg ctataagaac ccgttacaaa
     7561 taaaatacca caggattccg ccacctgagc cagcttttga ttgatttctc ttcccttatt
     7621 acttccacca gtcatggcat tgatataaaa aggaaagtcc cactttcgac cagcaaactc
     7681 tgtcgaaaga tcgatttcat ccagattgta aagaggcaag gaagaatgaa tcagctccac
     7741 ctcatcaaag ctattatagg aacttttctg ctcaagggca tagaggatat gctcgtcctt
     7801 acgatttgtc gtcatgtcct atcctttctt gatataagag ctcaatcccc agatcggccc
     7861 aacgattttt taaggttttg gttgattgcg catcaaaact cagggcgatg ccacagtcac
     7921 caccaccagc accactactc ttggcaacgg tctgcaaatc ttgactggct tctttcaact
     7981 gtctaagcaa aggcgtgtaa atatctgtac tcaagccttc taaaagcttg ctggctactt
     8041 ctacttgatc gataatcttt tctgatttcc cctgttccaa ggcttctacc agagaagtca
     8101 ccgtttcttt tgaggaagtt aaaaaatttt gattgatatt ttgcttgatt tgctggacca
     8161 tgtgactcga tacagccact tccttggtcc atcccactaa gaaatcacat tctaaagttg
     8221 gtttcacttg tgaaattgaa aagccccaat cacgctccag aactgtcgcc aagttttctt
     8281 cttctaacca agcagccacc ttctggcgat caaatgactg gtagagaacc aaatcctctg
     8341 ccacaataca ggcaaggtcg cccatggaac cattgtctcc tcgcttaagc aagacagcgc
     8401 tagtcagctt gaacaagagc tcctgatcaa cagaaacatc atacagagcc agtaaagcct
     8461 tgacaaccaa gacaacgacg ctgccactag aacctagacc aaactttttc ccttctcgtt
     8521 ccattttgcc acagatttct agagaaaaag gtcttaaatt ctgaccacga acagcgagga
     8581 agtctcccat caaagcaatc gtttcttgaa tcaagctata gtcaggatta ggccttaagt
     8641 ccactgcgaa atcaaacata tctgaataga tacggtagct gtcagaaaaa gcaatctcag
     8701 ccctcatata gatgggaata tcctttatca aagctaactg ccctggctct aaaatagcat
     8761 attcacctgc ccaatagagt tttccgcaag ttttaacagc aatcatcttg actcaaatcc
     8821 tttgtttttg acacaatcaa gcgataacga tgaccgaaaa tttctgataa atgctccaag
     8881 tctttctcct gacagaagac cttaacattg ggaccagcat ccatggtaaa gtagcaggcc
     8941 tctcctttct cacgaagctg gcgaacaaag gccatagcct cataagaggc atccgtcaga
     9001 taagaaaagg ctggactagc agtctttgtc gtagcatgca tagccagggc atttttctcc
     9061 gttaattctc caatcttggc aaaatcattt tccttgagat aaatcagcat atcctgatag
     9121 tccttctcag actgacgaac ccagtcgtcg aaagtcgtcg aggtttccac acaaagtttc
     9181 atcccgtcac ggctagagat tggttttttc ttgtcctcta gcaccaacat aatcatagct
     9241 agtttcaagt ctgtctctac agggtaaatt tctccactat ccttatccca ggctcctagt
     9301 ggtccataaa aactccgaga agaagaacct gaggcaaatt tggcttcctg tgccaactga
     9361 cttctatcca atccaagctt gaaataagca ttacaagcct tgaccagggc ggacaaacca
     9421 ctagaacttg aggacagacc cgctgccgta ggcatattgt tttgagtatc gatacggaca
     9481 aagccctcac cagctggacg ataacggtca ataatcttac tcatcttggc atgctcgacc
     9541 tcattttgta gctgaccatt gatgtaaaat tcgtcagctg ttacattggc tggtaaaggc
     9601 gacaaggtcg tctctgtata catattttcc aaagttagag aaatactgct agtagcaggc
     9661 accatctctt tttctttttt ctttccccaa tatttgataa tagcaatatt tgcgtaggaa
     9721 cgtactgtta caggctctct atccatgtct gaacagctcc tttctcttct aatctttctg
     9781 ctagttcttg tgcgtgtgtc aaattggtta ccaaggctat gatacaacct cctagcccac
     9841 caccgctcat cttggcaccc agagcaccat ggctaagagt cgtttcaacc aaaaagtctg
     9901 cctcagggct actgactcca atttctttta aatgtaaatg cgcttgactg aggatttgtc
     9961 ccagtccttc agcatctttt tgtgaaatcg caacttctgc ttgctgggtt aattctccca
    10021 aggcatgcaa aaacggtagg gcatccttgc ccttattttg aaccacttgg atggcttcac
    10081 gagtatgacc ataaacaccc gtatcggcaa tcaccaaata ggcggataaa tccatctcaa
    10141 gttctgtaaa tcctacgttc ttgataaagc gaataggttg gtcactaaga caggtcttag
    10201 catccaaacc actaggattc atatgggcaa tcatttcagc tcgattgacc aagatttcta
    10261 gtacatcatg aggcagatca gcctgatagt agtcaaatac tgcacgaatg gccgctatgc
    10321 tgatagccgc tgacgaaccc atcccccgtt tctcagggat agccgagtca atctcacaac
    10381 gaatgcaggc ttctgtgata ttcaaatact ccagtgaggc ataaaccgcc atggacaagg
    10441 tatcctcctc ataaaggcgc caaggactct ctgcaggaac taccttacag gtcacctcca
    10501 cctccaaaag aggcagggaa atggcaggat aaccgtaaac gaccgcatgt tcccctatta
    10561 aaattatctt actatgtgcc tgaccgacac caactttttt tgtcattttt tccttttact
    10621 agacgaaaaa acgtcttatt tttcatacaa gtattaattc tttcctatct attttattat
    10681 attttcacaa aaaaagcgat tgtttccatt cacaatcgct tctttcatta ttgaacccat
    10741 tcgccattat agttgacaga atagccatct acggtcgtat tcactgccaa ggcacctgag
    10801 cgctataagc gtagtaccat ctgccattga cctggaacca acctgtcgtc atagaacgac
    10861 gaaagaaact ccataccatt aagtaaagag gaaagtcgtg agggagcatg cgccattgac
    10921 aacctgtttt agtgacgtac aaagtctcat taacaagtac tcgtttcggc catttatagg
    10981 tgcggtgttt ggagaaatag ggttcaatct tcgcccattc ttgatcgttt aaatcagtat
    11041 catatgcttt gcgtatcata actctagctt aacatttttt tgtgaataca ggttctaaat
    11101 aatcgaccac gaaaatttct taagtggaaa acgccttatg aagtatgcta cgggaaagtt
    11161 atgcacttaa tttgacaatt caagatgtaa aaatatatac tatagtagat tgaaactaga
    11221 atagtacacc tctacttcta aaatattgtt agaaatcgat ttgactgtcc tgatcgattt
    11281 atcctgttat tatctcattt tactataata tttgataagt tatcctaaaa gtattattat
    11341 gttgttgtgt tatagattga ttgaatctaa ctaaaggatc ctattcaatt actagaacta
    11401 tcacatactc aaggtcagct cacagatgag caactatttt ggttacaatg tctactaaat
    11461 ttaagtcaaa caaataattt agtcaaaatt aaaaaaatag aggaacataa atatgattac
    11521 aaaacagaat gtaatagtgt tctacaattt ttactagata aaactgtaaa ttctgaagga
    11581 aggatcactt cttcaacaga atttggaaat ttcgtaagta atttatcatt ccaacacgga
    11641 atagctggac tactgtttcc tctaaataaa ttgtaccccc cagaactgga ttctaaaata
    11701 ctctctatca tcaagaaggc agtgacaatt agaacgacac acacatatga atatcaatac
    11761 tcactgctat ttggtgatgc aggctatcta tggttactcc tacatttatt ttctatcagt
    11821 aaaaatcaat actatctaca attagcaaac gtcaccgcta aaaaattaat agagaattat
    11881 gatactctag aggaaataga ctttgcattg ggaaaatctg gtgtcctatt atcattaata
    11941 aaatactatc aatttaccaa tgacaatact cttaaaattt tcatccacaa tagtataggg
    12001 gaaatttatc attatttcct acaaagagat acagccaaag aaagcatttt agactatagc
    12061 tttgctcatg gatattgtgg aattgcatat gctttatttg cctattctaa agtcttagaa
    12121 ccttctatgt tttataatga tctccataca ttccatactg aattaaaaaa attattagaa
    12181 aaagttactt ctaatactga aaatttagga aatttacaac tttcttggtg caaaggaatt
    12241 tccggaataa tcttatatct ttgtatgtac gattgtgacg gaaacaaaga tattattagt
    12301 aaatatcaag aatttgtttt taaccatcat ctaaaaatga tgacaggata ttgccacgga
    12361 ataactagct tactacaaac cactgtctac aatcaaaaca aattactgat gaaaaaaatc
    12421 caacaggtaa ttttagcatg ttctgaacga gatgatcacg gtttactgat gtttcaagga
    12481 gatagtggta aagcagattt gtttgacttc ggaataggaa gcatggggta tattggtgtc
    12541 tattaaataa taaattccca ttcgatgtgc agacataagg agaaaagtat gaaattattt
    12601 tggacaaaca acatatatag acagttgctg ctaaacagct gtttttcatc attcggcgac
    12661 agtattttct acctcgccat tatcaattat gtggctcagt acaatttcgc tccgctagcg
    12721 attttactga tttccatttc agagatggtt cccctactat cgcaactctt tctcgggatt
    12781 ctaggagatt ttcaagaaaa tagagtcaaa cacgcactct ggattgccaa aatcaaaatc
    12841 ctgctctacg ctattttgac agtatttctc gtcttgtcgc ccttttcatt agtttcagtc
    12901 attatgattg tcatcatcaa cctcatctct gacaccttga gctacctgtc tgcctacatg
    12961 atgaacgccc tctacatcag tgtaattaag gacgacctgc atgatgccat ggggttcagg
    13021 cagtctctga tgagggttgt ccgtattgtc gccaatctgg ctggcgcatt ccttatcaat
    13081 gttataagta ttcaaactat ttcccttatc aacactctga cttttgtcat tgcctttttg
    13141 ggcctgtatg ttattcgaca taccttgtat gaggttgaaa aaagaattga aatgtcacat
    13201 acagcactga gttttaagaa atattttcaa catcttaaac agtcgctggc tgtgctcctg
    13261 aggttaaaag ataccgtcat actactgttt ctgacgacca gtatgattgc catcttggat
    13321 gtgtcccctc ggctgattgc cctccgcttc atccaacaga cactagcaca actgagcatt
    13381 gggcaactcc tcgccctgct ctccatcatc atgtcttgtg gagctatcct tggcaatatg
    13441 accagcagta atctatttaa aaatatccgt ttcacgcacc tcttggtttt ctgtgagatt
    13501 tccctattga ctctaataac tagtatcctt tgtcaagcct atatcgtaat tttcatgacc
    13561 agtttcatca gttctacgat tatcggcatt ctcagccctc gcctacaagc agctgtcttt
    13621 gcccatatcc ccagtgacaa gatggggacg gtgggctctg ctctgagcac agtggacatt
    13681 ctcgccccgt ccctgctctc cctattagcc ctatccatag catcgggcgt ttcggtgcag
    13741 ttagcattga tatttttgta tcttatttta attgctctta tcttttgtca atggttagtc
    13801 aagttcaaca ctcataacta acgaaaaagc atgtgtagat ttcacatgct tttaatctcc
    13861 ccaatcgtca ggtcaagtac aacaaagtca cttctttgat taagcgagtg ttctaatata
    13921 attataagcg ccctgtcatt accgaaccca ttcgccatta tagttgacag aatagccatc
    13981 tacggtcgta ttcactgcca aagcacctga gctataagca tagtaccagt tgccattgac
    14041 ctggaaccaa cctgtcttca tgtctccatt acctgcattt aggtagtacc aagttgaacc
    14101 atcttgatac caaccagttg ccatagctcc tgatgaacgg agatagtacc atttgttccc
    14161 aaggttttgc caacctgttt tcatatcgcc atttgggtgg tctaaataat accaagtggt
    14221 accttcctga taccagccag tggccattgc tcctgaggaa cggaggtagt accacttatt
    14281 acctagatat tgccaacctg tttgcataat accagttgtt ggatctaggt agtaccaagt
    14341 cgaatcatcg tttatccacc ccgcacgtct ttcaccacca aggtagtttt ctccattaat
    14401 ttccgtctta gctagataat accagttaga ctgatcataa agccaacctg tctctaaaga
    14461 atgattttga ttaaagtaat agttcgtata ataacgcttc tcttctttat cttctgaatc
    14521 ttcacgtttt tccccgtact ttcttccaac actgtcttta gttttaatct ctaatgtttt
    14581 ccaaccaaca aactcttgta gcactccatt tttatcgaag tagtaccact ctgactttgg
    14641 aaaaccttct aatctgatac catttgggta aggaccaatt gtactacctt tagatggaaa
    14701 cgggatatat tgccagccga caaccatctc tccagataga gaatcaaaat aatagtactt
    14761 accatcaatc actcgccagt aggtttcttt gaggtccccc tttttgtagt aggttcttcc
    14821 gttttcttgg acaaactgcc atccttcaga atcatctgca aatactgtac tggtccctag
    14881 caaaccaaag aaaaatactg tcagtccaac ttgcatagtt tttttcaaaa ttttcatcta
    14941 tataccctcc aatattaaat ccactcacca gatgaggcga aattataaac tttaccatcg
    15001 atagtttggc tacctgtaac cattgctcca tttgaattga gataatacca ttttccattt
    15061 acttttgtcc aacctatttt catatctcca ttagaaggat ctaaatagta ccaagttgaa
    15121 ccatcttgat accagccagt taccatagct cctgatgaac ggaggtagta ccacttgtta
    15181 ccaaggtatt gccatcctgt tttcatatca ccatttttat tatctaagta ataccatttg
    15241 cctcgtacat atttccaacc tgttgccata gaaccagagg agccaaaata ataccatttt
    15301 ccgtttactt tttgccaatc tgtaagcatc ttacctgaag catctaggta gtaccatgga
    15361 gcaggtttgc ttctatcaat gtcaatagta acatgaaaat cttgagtcca acccttagca
    15421 acttcaccaa ttggtagtgg attgtaagaa tcatcgccaa aatttcctag cttatttaaa
    15481 taataccaat gaccctcttc ataaatccag cctgtcttta cagcataatt attatcaaaa
    15541 taataagttc tcttttcagc agatagagga tattgttcac cgtatacttt tcctgtattt
    15601 tcagacgttt ttgcctctag tacttgttta tctgtttgtt ctagcaaagc accatcttgt
    15661 ccaaaatagt accacttctc ctgaaggcca atttcattaa ctggttggtt atcgaataaa
    15721 ttatcacgat aacctgttcc aggaatttct aagtattgcc aaccgacaac catctctcca
    15781 atatcaccaa aatagtaagt tttaccgtct attttatgcc aatagattgc tttatgatca
    15841 tcttttacat aatattttct attatcctta tcaacaaatc ggccacctgt ggtattcgca
    15901 aataccgtat ttgtagctag caaaccaaag aaaaagactg ctaatgcgac ttgcatcatt
    15961 tttttcaaaa gcttcatttt atatatcctc ctaaaacgat tgtagtaaaa actagattgt
    16021 atgtcaatat ataaaaactc ctcaaaaaag cagttacaca actgcaactg cttttctatt
    16081 cttgcatggt atatccaaca ccacgcacag ttttaatgta gcttttttgg cctttaacat
    16141 caagcttgct ccgtagatag cggatataga catctacgat atttgtctcg gtcgcacttt
    16201 catacttcca aacactttcc aacaattgct cacgagtcaa tactttcttg cttcccataa
    16261 gtgtcgccaa aaggtcatac tcacggcgtg tcagagcaat catctcttca ccacgataaa
    16321 ccgtgtgatg ttcaacatct atcctaagat tgcggtaggt ccttggaact ttcatcagac
    16381 tgcagtgttg atcaatgaag tcccgacctc ggaagatcgc cgaaatacgc gctaccagat
    16441 tttcgataag gactggctta tagatgtatg aaactgcaaa acgctgaaca acttccagct
    16501 cttcttgcaa gtcttcccaa tgatctaaaa tcatgatgac tgaggcaggt ttagttcggc
    16561 tcaatttttc tgcaaaatcc tgagccatca tatctcccag attaacgttc aataacatca
    16621 aatcatagtc tgtctgaaga gccatggaga gggctttttg cccctcctct accagatcaa
    16681 cccgatactg ctctttctgg agttccaaac ttaaaaaatg agctagattt cgttctttct
    16741 caagtaataa aatccgtttc cccatggctg acctacttat ttttcgtcat accaagagta
    16801 gtggaaggtt ccttctttgt ctttacgttg gtaagtgtga gcaccaaagt agtcacgttg
    16861 tgcttggatc aagttagctg gaaggtcagc tgaacggtag ctatcaaagt aagtaatagc
    16921 tgctgagaaa gttggcactg gcacacctgc ttgaaccgca agagctacga tatcacgtac
    16981 tgcttgttgg tacttagcag taacatccaa gaagtactcg tccaaaagaa ggttggcaag
    17041 atctgcatcg cggttgtaag catctgtaat cttttgcaag aaacgagaac ggatgataca
    17101 gccatcacgc cagatagatg cgatatctgc aaatggcaag ttccagttgt tttctttaga
    17161 ggctacacgc aattgagcaa atccttgtgc gtatgaaatg atttttgaga agtaaagggc
    17221 ttgacggatc ttttcaatca attcagcctt gtctccttca aagttgaagg cagctggttt
    17281 tggaagcacc ttgctagcat gtacacgttc ttctttgtaa gttgaaatgt agcgtgcaaa
    17341 cactgactca gtaatcagtg acaatggtac accaaggtca agagatgatt ggctagtcca
    17401 tttaccagtt cccttgttac ctgcagcatc aaggatgtag tctacgattg gtccatcttg
    17461 gccttcatcg tctttacggc tcaagatatc agctgtgatt tcaatcaagt agctgtctaa
    17521 ttcacccttg ttccactcag taaagatttc agccatatct tctgcagaaa ggcctagcaa
    17581 gtgttgcatc aagtcatagc tttctgcgat caattgcata tcaccgtact caataccatt
    17641 gtgaaccatt ttcacatagt gaccagctcc atcaggaccg atgtaagtca cacatggttt
    17701 gccatcttct ggtgctttag ctgagatttc ttcaagaaca tccgcaacca attcgtaggc
    17761 ttctttttgt ccaccaggca tgatagaagg accttcaagg gcaccttttt caccaccaga
    17821 aaccccagta ccgataaagt tgataccaga gtttgccaat tcttcattac gacggatggt
    17881 atctttgtag aaagtatttc ctccgtcaat caagatatca cccttgtcaa ggtgtggaag
    17941 aagggcttgg atagtagcat ctgtaccagg tccagcttga accatcagca tgatacgacg
    18001 aggtttttcg attgagttta caaaactttc aacgtcatag cttggtacaa agttcttttc
    18061 aggatggcaa gcaatcacat cttccgtttt ttctttacta cggttgtaga tagcaactgt
    18121 gtaaccacga gattcaatat taagggcaag gttacgaccc attacggcca tacctacgac
    18181 accaaagtta gcttttgtca tttgacactc ctcttgtttc atttgtttta ttttatcatt
    18241 tttacttttg aaaagaaaga attttgtaac gactgcttag taatctaagt catccgcatg
    18301 accagcgcca tttccgacaa agtagcctgt cttacagtta agggtaaaga gataggttcc
    18361 atctggcttg tagaggttgt aataaccatt gccgttaacg atattgacac gttcaaggat
    18421 atattggtct ccagtgatat agccacgtga acgtgaagtc gctagaattt gttccaagac
    18481 accatccgca aaatcccagg cagagttatt actatcatca atagcagact gattataggc
    18541 aacacgactg gcacttcttt gaacagcaac ccctgcactc gagagaccca tattgacttc
    18601 actgcgacta cttctagtct catttgaact acttggtttt ggctcactag tcgtatttga
    18661 acttgcttga cttgaacttg agctgctagt ttgacttgaa cttgagctag aagtacttgt
    18721 ttgctggctc ttaccaagac tgatagcctt atctagcact ttatcaagct ccgtatttcc
    18781 agttttaata tccgtaaatt tagcatccga tttggctttg gcattggtat ccaacacacc
    18841 atccacaata gctggtttct caaattgagc attgacatct tgaatagcct tgatttgcgt
    18901 tgctagacta tcatatttag atttggcaag cgtatgttca cgactacctt ccagcttatc
    18961 aagtaaagtc ttgagttgac tcagtttatc aaactggcta tttttcaaag ccgttttatt
    19021 gctatctgtg taaaaggcgt cataaagtgt attaaaatca tccacatccg attgattggc
    19081 tgtagttgat tgagaagttt caatttcctt agtcgaacga gccacttgac ggtagacata
    19141 ataagcactg acacaaataa ttactgatac aagcgccaaa acggtcaaaa taaagccttt
    19201 tttacttttc ttttctgagt cctcttgatc cagacgagaa aggttttgct cctcttccac
    19261 ttcttcagtc atttctgttg gattttcatc atctagcaat agaggatcca agccttgctc
    19321 ctcatcgtcc agaggcaagg gtagtaagat gtcttcagaa gatggaactt cctccgaaga
    19381 agcttctgac ttctctacag cctcacgcat ctcttgaatt aaatcatcca gactctgagt
    19441 ttcaacgaac tcctcttttt tgtattgacg agtcgcaaac ttatccgcct caatttcatc
    19501 tctgtgttgc ttaacatact tgtccaaaat ggaatcctca ggcaagactc ctgattccac
    19561 ttcttcattt ttacgaatag cttgaccaac tgttagctct tttgcttcat caaaatcaaa
    19621 ttgcggttct tgaccttctt ttttatgacg atttcgtctt tttttactca tgagtatccc
    19681 tttctatttt acctcttgcc gtttgacacg ctgaccaaaa tattgatata gatccacttt
    19741 caaggttccg ttgtataact tacgcttctt atctgcttgg ctaccatact tgctttcaaa
    19801 agcttcatca ctagtcagga taaatttgct ccaagttttc agcggtgcaa atacttgccc
    19861 catctcagca tagagcttgg tcacccctgc atcatctgac aaacgttcac cataaggcgg
    19921 attggaaatg attactccat tgattttatc ggaacgtaaa tcctgcacgc gcatctgctt
    19981 aaaagtaatg tctcctgcaa caccagctac ctgagcattg gccttagcaa tttccaccat
    20041 gcgagcatca atatcacagc ccatgatatc cagctcaagc tcacggtcta cttttttagc
    20101 cgcttctgtg cgcacttctt gaatcaagcg atcgctgatc cagttccatt cctcaaatgc
    20161 aaaagagcga cgaagacctg gcgccatctt tctagcaatc ataactgcct caatacagaa
    20221 agtccccgaa ccacaggtcg gatcaatcaa aggcttgtct ggataccagt tagaaagttg
    20281 taaaatggct gctgccatat tttccttgat aggagcgcca cctttttcgg tacgataacc
    20341 acgtttaaag aggctagacc cggtcgtatc aatcatgaca gttgccacat ctttgagaat
    20401 agagacctca atcttaaact ctgggccatt ctccatcaga ggaacccctt ctgggcgagc
    20461 atagtgtttc tgcaatttct tgacaacagc tttcttagaa atagcctgaa cactgggctc
    20521 attgtgaagt ttggacttaa cacatttagc ttttgaaatc gggaaccgag ctccaagtgg
    20581 taaataattt tcccaatcca aagcgaaaac tccctgaaat agctcttcaa aagtcttagc
    20641 tgggaacgtt cctacgataa ttttgatacg atctgctgcc cgaagccaaa ggttggtttc
    20701 gataatagct ctcacgtctc cttgaaaacg aacacgtcca ttttcaacct gacaatcgta
    20761 gcccaactct cgcacttcac gaccaacgac agcctcaagc cctgctgcca cagttgcaat
    20821 taaattaaat tcttttttca tgttacagtc ttgcaagacc tttctatatg tccactttaa
    20881 aaaatgaggt tgagaaaatt tctcagcccc aacctatatg caattttcta taagccatgt
    20941 tttgttccag aagtgactag gaccacttcc ttcgataatc atctgtctac cactaacagc
    21001 tctagctgat agcagtcaga atactacgtt cgtttccgcg tactccatgc cccgaccaaa
    21061 atttgggttg ctagcttgag gggtttaccg cgttccactc tctctgtttc cagaaagact
    21121 ccgtcactgt ggcactttca agcctactct ggcctatcca aggacttagc catttcaact
    21181 gccgtaacga tttctcgtcc ctaggcttat ggtttcgcct agcacaaaca ctacaggcat
    21241 cacagcctgt gctagcatgg actttcctca tgagaaacaa ttctcctcac gcgattatcc
    21301 aaaaattgca catctcaaat aactacttaa aaatctgagt tatctaaaat ttgtttacca
    21361 aaaacttctt tttccaatct attcaggcgt ttcaaaatat caaaattcgt catagaactt
    21421 gtaattgccg cttcaagggg ttctgcttga actggtgaag gtttcggttt acgagttaat
    21481 tcttccttca aatccgcaat ttcctgacga agtgacttga ccaaggcagc ataggtttca
    21541 tagtccttga tgacatcgtc taaaaactcg tcaacttcta ctttattata gccacggacc
    21601 tcacgtccaa actcttgttc aaaaatatct ttcgctgaaa aaataatact tgccatgtct
    21661 ctctccattc tcgcttgcta gtattattat ataaaaaaag gcaaacaaaa atcaaggtca
    21721 aagcttcaat tttcggaaaa attttcagca agttcattta attcatcaaa tgttaatctc
    21781 tttataaaat agtcctcttg atttttcatc ttttggtaaa aataagctag ttttgtttca
    21841 ttttcttcat cataaaaaag ataggaacta gtcgtgtttt ccagcaaaaa ctgctggtaa
    21901 tctcttaact gccccttgtg ttcatagcga ggataggcat atttgacaaa gtctacctgc
    21961 ttaaagcgac tcagtttcat ctgattgcct tcattccaat tttccccatg ggtttcaaaa
    22021 gcaaaaatgg tggccaactg gaaaccgtat tcagttttca tctcctgagc aacctctaaa
    22081 acccaatatt caaaacccaa actccctgta aacacaagcc aagacacccc atctgctgcc
    22141 atagcctcta aatctttacg tatcgctttt ttaatcaatt taagacgagg atccttatca
    22201 gaaaataaac ccaaatcaaa agcagaatag cctaaaacca aagctgtagc catttttaac
    22261 cctttctgtg caaattatgg tataataaag tgatgttatt gtaccaataa ggagaattat
    22321 ggtcaactat ccacataaag tttcatcaca aaaaagacaa acatctcttt ctcaacccaa
    22381 aaatttcgca aatcgaggaa tgtcttttga aaagatgatc aatgctacca acgactacta
    22441 tttgtctcag ggcttggctg ttatacataa gaaaccaact cctattcaaa tcgtacaagt
    22501 ggactatcca caacgaagtc gtgccaagat tgttgaagcc tattttcgac aagcttcaac
    22561 gacggactat tctggcgttt ataatggata ttacatcgac tttgaagtca aggaaacaaa
    22621 acaaaaacgt gcgattccga tgaaaaattt tcatccacat cagattcagc atatggaaca
    22681 agtccttgcc caacaaggaa tctgctttgt ccttcttcac ttttcttctc agcaagaaac
    22741 ctacttattg ccggcattcg atttgattcg cttctatcat caagataagg gacaaaaatc
    22801 aatgccactt gaatatattc gagaatatgg atatgaaatc aaggctggtg ccttccctca
    22861 aattccttat ctcaatgtta tcaaagaaca tttattaggt ggtaaaacaa gatgaacaaa
    22921 ccaacgattc tgcgcctaat caagtatctg agcattagct tcttaagctt ggttatcgca
    22981 gccattgtct taggcggagg agtttttttc tactacgtta gcaaggctcc tagcctatcc
    23041 gagagtaaac tagttgcaac aacttctagt aaaatctacg acaataaaaa tcaactcatt
    23101 gctgacttgg gttctgaacg ccgcgtcaat gcccaagcta atgatattcc cacagatttg
    23161 gttaaggcaa tcgtttctat cgaagaccat cgcttcttcg accacagggg gattgatacc
    23221 atccgtatcc tgggagcttt cttgcgcaat ctgcaaagca attccctcca aggtggatca
    23281 actctcaccc aacagttgat taagttgact tacttttcaa cttcgacttc cgaccagact
    23341 atttctcgta aggctcagga agcttggtta gcgattcagt tagaacaaaa agcaaccaag
    23401 caagaaatct tgacctacta tataaataag gtctacatgt ctaatgggaa ctatggaatg
    23461 cagacagcag ctcaaaacta ctatggtaaa gacctcaata atttaagttt acctcagtta
    23521 gccttgctgg ctggaatgcc tcaggcacca aaccaatatg acccctattc acatccagaa
    23581 gcagcccaag accgccgaaa cttggtctta tctgaaatga aaaatcaagg ctacatctct
    23641 gctgaacagt atgagaaagc agtcaataca ccaattactg atggactaca aagtctcaaa
    23701 tcagcaagta attaccctgc ttacatggat aattacctca aggaagtcat caatcaagtt
    23761 gaagaagaaa caggctataa cctactcaca actgggatgg atgtctacac aaatgtagac
    23821 caagaagctc aaaaacatct gtgggatatt tacaatacag acgaatacgt tgcctatcca
    23881 gacgatgaat tgcaagtcgc ttctaccatt gttgatgttt ctaacggtaa agtcattgcc
    23941 cagctaggag cacgccatca gtcaagtaat gtttccttcg gaattaacca agcagtagaa
    24001 acaaaccgcg actggggatc aactatgaaa ccgatcacag actatgctcc tgccttggag
    24061 tacggtgtct acgattcaac tgctactatc gttcacgatg agccctataa ctaccctggg
    24121 acaaatactc ctgtttataa ctgggatagg ggctactttg gcaacatcac cttgcaatac
    24181 gccctgcaac aatcgcgaaa cgtcccagcc gtggaaactc taaacaaggt cggactcaac
    24241 cgcgccaaga ctttcctaaa tggtctagga atcgactacc caagtattca ctactcaaat
    24301 gccatttcaa gtaacacaac cgaatcagac aaaaaatatg gagcaagtag tgaaaagatg
    24361 gctgctgctt acgctgcctt tgcaaatggt ggaacttact ataaaccaat gtatatccat
    24421 aaagtcgtct ttagtgatgg gagtgaaaaa gagttctcta atgtcggaac tcgtgccatg
    24481 aaggaaacga cagcctatat gatgaccgac atgatgaaaa cagtcttgac ttatggaact
    24541 ggacgaaatg cctatcttgc ttggctccct caggctggta aaacaggaac ctctaactat
    24601 acagacgagg aaattgaaaa ccacatcaag acctctcaat ttgtagcacc tgatgaacta
    24661 tttgctggct atacgcgtaa atattcaatg gctgtatgga caggctattc taaccgtctg
    24721 acaccacttg taggcaatgg ccttacggtc gctgccaaag tttaccgctc tatgatgacc
    24781 tacctgtctg aaggaagcaa tccagaagat tggaatatac cagaggggct ctacagaaat
    24841 ggagaattcg tatttaaaaa tggtgctcgt tctacgtgga actcacctgc tccacaacaa
    24901 cccccatcaa ctgaaagttc aagctcatca tcagatagtt caacttcaca gtctagctca
    24961 accactccaa gcacaaataa tagtacgact accaatccta acaataatac gcaacaatca
    25021 aatacaaccc ctgatcaaca aaatcagaat cctcaaccag cacaaccata acatttatca
    25081 cccagatttt tctgggtgat tttgtcatag cactattgta tttatgtgct taacaaaagc
    25141 ctgagaagac atcttctcag gctttttctg tactataaac ctcattggaa aagatagaga
    25201 ctgcttccgt aatcttgtta agaggtttta ctaaatacta gtctttcttc gtttttacta
    25261 caaagagagc agatagggct agactaacac ttgctaggat gagggctgtg tcagattgac
    25321 tctcacctgt tgctggcaag atttgttcag gtgtttctgg tctagctatt tcttgcttat
    25381 aatctggcgt cttaccttgc tcggaagcta aagatctaag tttaaactca ggtttctcta
    25441 cagttggagc atctggtttc gtagcagaat cttttaattg gttgagataa tctgcaaagt
    25501 attccaccat tctttccgtc aagagatggt tatccgtcgc atatttcatg cttgcctgaa
    25561 cgctagctac ttcctcttga ttgtctttgt ctgttaattt ctgagcctta accaaagctg
    25621 cttcatagcc tgacaagtca agaggtgttt ctgctacctg tggacgagta aagataagtt
    25681 ccgctgcaga ttggtattta tctccaccat ctccgtatgt cttggtacca gtaaggacaa
    25741 ttttcttagc cttgattgtc ttaccaaagt caatatcttt tggtttgttg ttatttggcc
    25801 aatcagttgc agtaaaggta tgctccttgc cagactcatc tgtcacaaca agtttcacat
    25861 ctcgcaagtt accatttgaa cctgatccac gcggaacata gcgaagtcct gtgatttcag
    25921 ttggttcttt caagaccata gttgcaggct tgcctacatc tccaccattc caagatgtat
    25981 gccatagact agacacattg ccatcaaagg catttgcaag accttcttga gcctgagcag
    26041 gagctgtaag acttgcaaag tcatctgcta ccaaagccgt cttcttctga accaaagcat
    26101 tcttcaaagc ttcaatcttg gcaatctctg cacgcgcttc ttccacactg atatcatcat
    26161 cggcctgact gaggttaaag accgcctctt tcaaagcatc catagactct ttggtgtagt
    26221 tagtcatggc aaccgttggc aagtagttct tcagagcatt ttctgtcaac atcttacctg
    26281 ttagggtaat ttcttcgatt tgaagattat ccatcatgaa gtcgttataa ccacggaagt
    26341 tggcatttcc accagaatca ccacgagtat tacttgcatt tccagttgag tagataccta
    26401 cccaagtatc gcctgtttct gcacctgtca caaggaaggt tgccttcttg gctttcttag
    26461 aatctgtcca agtatttggc aattcatgca tttccaagtt gcttgcttga gtaccacgac
    26521 gacctgactg gaattctccc ttaccgacta caaaagcata ggtattgtct gatcctgctt
    26581 cgtattcaaa ggttacacgg taggtcttac ctgcttcaaa acggaagttt tgtgggatgg
    26641 tttggtaaac caagttacga cggctcacta gtccatttgt cttgagtgac caatttcctt
    26701 cgataacatc atcgactttc ttaccattcc aaccacgttg tgtatatgga ttgtgttttt
    26761 cagacaagtg agtgcggtta tcttcaacac cttcgacacc acccactaca aatgggaaga
    26821 taccctgagc aacattttca aagtcttgct tgaaggtgcc tttacctgta tcatgcttgt
    26881 ctccgtacat gcttgaattg ttttcaaagg tacgaatttc atcaaagtaa gttgcttgat
    26941 caccagcttc acgactcaat gtcagagtaa catttgagac gtccgctcca gttgtaaaga
    27001 aggcgtacat gttttggaag taacttgtat cgtcaactgt agcattgtca cgacgtgtat
    27061 tgtgggcgta ggccttaaca tagttgagcg cgagagactt attggtataa gtagtcactt
    27121 ctttttcacc agtattcaca gtgatacttg ccttggcatt actacggtta tctacaccaa
    27181 cataaacggc atacttggta tttggtttca agccagttaa tttctgagtg agactaactt
    27241 tttctttgtt tccttgaata cgaagcatat cgtttgcccc ttgagacttg acaatttctg
    27301 ccttagaagc atcgcctgaa atggtccaat gtttcaaggt accgctatta aatccttggt
    27361 catagatgtg catgccttca ctccatgaca tttcaggatt agtttgtttc gaacgataga
    27421 gaacgtatgg ttgatttgct agaagatcta gggtaatttt accatctttt acagttagtt
    27481 cttgctcttc tgtcttacct tggtcagtta gcttgtaaag gtaaaccttg ctctttgccc
    27541 aatcgcttgg aagggtccaa gttgttgcac cggcctgcgt attgaagtag tacatctttt
    27601 ccttatcagt agaaagtttc ttaccatttg catcccagtt ccaaggagtc aagtaagctg
    27661 aaccatcttg gatgacacgt ccgttgagcg ttactgtacg ttcgcgatat tgtggactat
    27721 tgacatcatt tgacttacga gttacaacta ctttattatt gtcagcatct accaattcca
    27781 ctcgcatttc tggagtccat ttataggtgc taccgttatc ggtcatagtc accggtgtac
    27841 cattttccca tttacttaca gtgaagtgtt ggaagtactt agtcatgacg tcatgggcaa
    27901 ataagttggt tacatagcca ttgtagtcac ttcttccctg ccagccttca aagtctttca
    27961 tgctgtagcc acctagcagt ggatagttgg ctgcaccacc ataacttctg tagtccccta
    28021 cccaagcatc tttttggtgg ttacggataa agcgggtgat ggcactgttg atacctttat
    28081 tggtgtagcc accgtaggtc aagtcagctg cccagtgatg gaaggtagag tcgtactcac
    28141 caccatggcc ccactcgatc gcaaagcgcc agccttgttt gttaatttct ttagcaagaa
    28201 cgtgggtagc ccaggcaccg ttatcacctg attgaccatt accccaaacg tccacataga
    28261 taaagtcgag accgtcacca agttttttct tcaaatcttc ccaacgtgcc aaacgaccat
    28321 gagctaggtc ataggcagca tcaatgttga taccttgatc tagccagttc caaccatagc
    28381 tatagcttcc atctggattc ttacggagaa ttttttcatt gaagtattta gactcaggat
    28441 aagtttctga agcgttaacg tggataccta gatgagctcc atatttctta gccttctcaa
    28501 ttagggtctt gaagtcttcg acaccaccga tacgcttacc aatatcagca tagttcaagt
    28561 gaccagagtc atggccttcg ctaccatatc ctttaaggag aacaccttgc ccaagaccat
    28621 ctgtatggag attgattttc ttgataccat ccaaggtcat aaggaatggg ttttgtgctt
    28681 gagaaccaaa gttcatcgcg atacggtaag ctgtgatatc cttaactttt tcccaacctt
    28741 gaggattgtt cataatgcta cgataagcaa tggcaccatc ttgccaatca acgttcttgt
    28801 ctgcattggc atcttcagtg ataacaacct tagcacttgg aagttccttc gtgtattctg
    28861 ggaaaacaat gcccttataa gctttttccc attgccattc agagctgtgg attcctacat
    28921 agttggcatt tccgactgtt tctttataag ctgtcaaacg agtccagtca ttcgaaccac
    28981 caccatagct gttttgagag ttactccaaa caccagcagc aagcttatct gtagaaacaa
    29041 atccatacat gtaaccctta gccaaatcct tcattggatt ggttacatcg atatgatcat
    29101 ctccgctgac atgcgtattg tttgacatgg ttgccccatc aaacttagca ccagtttgat
    29161 tactagaaac agagactaaa gcattgccga ggaaactaat agaagaaagt agtttgcttt
    29221 cgtcatcaat cttttgacct ggagtgactt gattgtggtt gacaatctta gtcacatcaa
    29281 agtgcaattg attgtctaca acttgcaagc gtactgtcat ttccgcattg attaagtgag
    29341 catcatcgcg aagcttcatc aagtactctg ctgttgtctc attgattttc ttataagtga
    29401 cttcaggggt gattcggtgg ttattgataa agacttggtt gaactgttgc acctgtcctg
    29461 gcaaagtatg cccgttcaag ctgtattcct tgacacgagg gaaggcttgg tcaatcactg
    29521 ctttgaggac cttagactga atcgtgtcat aagtcacctt gctatcatca acttcaggac
    29581 ctgtttcttt ttcagcaggg gtatcctctg tttttacccc ctcttggtta tccgttttaa
    29641 cgctaacaac tgttcgctca tcgtcataag agcccgcctt gagaagaatc ttcttctcat
    29701 ttttaagatg gtcattgacc gcagctggta gagtcactgt gtcaaagaga ttgacatcat
    29761 tattgctggc atttagctga ccgtctgact tgagagtgat agagagacgg tttgttgatc
    29821 ctgtttcagg agcagcaaca cgactacctc tataccaagt gctagttgtt ggagatttat
    29881 actcccagaa ccagccatcc ttgtcataac cgacaaaaac attattcttg gtatctttaa
    29941 atttcaaaaa gacaccaaag cgtgatttgc ccttttcaga atcatctttg aaggttaaat
    30001 caacagttgc atttccattg gcatcaacgg tcaagccctt cttttcaaac agggctggtt
    30061 tgcctgcgtt atcattttga gcagttgagg atagttggtt gtagcggaca cctttttctt
    30121 ctcggatagt gactgttccc tgttgctctt tattcgctac cgtttgccat tcaggggtta
    30181 ccgtcttagg tgtttcaggt ttagcagctg caggtttatc ctcttttggt ttttcttcag
    30241 ccggtttttc tttttcaagt gctaatagtt cttcttctgt cttaggtcca tctgtaactt
    30301 ctggagaacc ttggtcttct cccaccttag gcgcttcaaa atcacgccca tcattctctt
    30361 ttgctgttgc aagagcagta gctaaatcag ctggtaagtt cgccgtggaa ccagactgca
    30421 cgctatctgc aagaaccgga cttgtcccaa agaatgcagc tccaatcata acagaagcaa
    30481 cacctaatga aaatttccga atactatatt tacaacgttt ttcaaataat cctttattca
    30541 taaacttcta aatcctttca tttttgagca aacgtttaca ttttcttttt aaaaaatact
    30601 ccttcctctg aaagtgcaat gcttaactct gataaataaa aaataattat acttttaata
    30661 taacaaataa tagctgagaa agcaatagga aacaagtaaa attaacaaaa attttctcta
    30721 ttctgacaaa aagaggctcc aacttttggg ggtccgtaca ttttagaatc tttctttaca
    30781 aatgtaaaaa aggattcagc attcaaggga aatactaaat cctttcttat attttgcaac
    30841 agttatttca catgttttgc gagatcttct tgagcctttt tattagactc ttctttttct
    30901 ttcatccatt tttcctgagc tttttggtat tcatctacag tgactgcctt gtcttgaagt
    30961 tccaagtatt tatacaagac tggttcactt gtacctttat ttcctgacaa tgcaaatggt
    31021 attgtaaatg gtaccatctt agacaagatt ggacgccctg tacgagatgt agttggaata
    31081 atcaaagcac tatctgtcaa ccaagcttgg gctgcagcgt atttatcata gcgtttagca
    31141 acatctgtag tctcatcacc agcctcagta accaattttt cgtagtcata tagacctact
    31201 tttttagcag ctacattatc ttcccctgag tcaaacccta aatatgtttt agtactttct
    31261 cctacagaag gtttgataat atcaaggtag gttgatggat cggcaaagtc tggaccccaa
    31321 ccgacattat ctgataaatc ccagtcttcg ccagcagcat tttcagcaaa atatgtaata
    31381 ttgtttactt cgtctttttg tagttgttga atatcaataa tgacattatc agctcctaaa
    31441 gttgcttcca aggattgttt catagattgg acgcgctgaa cttttgtagt tgctgtttgg
    31501 tcaactggca tatccaaatg aattgggaat tggactcctt ctgcttgtaa ggctgattta
    31561 gctttagcaa attcagcctt ggctttttct ggattgtaaa gaccatcctg agaatctgca
    31621 agattaacat ccttccattc atccccataa gtgaccaatt tctctttgac catatcgcca
    31681 aagtttttac catctgcttg aacaaatgtt ggtggcacaa agagattacg caagatttta
    31741 cttgctccag tttgtccatt caactgagag gcataggctg tacggtcaaa tccaaaggca
    31801 atagcctgac ggaaatcctt gtttaagaga gcctttttag tcgatgcctt ttgttcgtcg
    31861 ctggtcttag atgtgtattt ataggactga cggtcaatat ttgtaccaac tagatacgta
    31921 atagagtctt gttgagtata gacaatattg tccttcatac tcttctcaag ttctgcgaaa
    31981 cttgcacttg ttggatagag acgagctgct gtaaggctac catctttaaa gttttctgca
    32041 ggtttgctgg tatcttgacc atcccagaat gacaatttaa ctttgtcaac atgcacattg
    32101 tccttatccc agtagttcgg atttttcgca aattcaacag aggatttggt cacaatggat
    32161 ttcaacaaat aaggaccgtt atacaagaga ctacttggat ccgtagcttt ggcaaaatca
    32221 tctccttttg aattcaaaaa ctcttcatta actggcgcaa gcacacccat ggttgtctta
    32281 gaattccaga agctttctgg tttgttcaaa gtgtactgaa ctgtctgttc atccagagcc
    32341 ttaattccta cttgtgagaa atctttgatt tcccctttta cataggcatc caaccctttg
    32401 attgattctt gaacaaggta aagagcatct gattttttat cagcagcata ttttaatcct
    32461 gttacaaagt cttgagcttt gactgccgcg tattcttcac cttcagaagt ataccatttt
    32521 gcatccttac ggatagtata agtgtaagtc aatccatcct tggatacaga ccaatcctca
    32581 gccatagacg gcacaaagtt cccgtagcga tcattttcta gcaaaccatc aaccacgtta
    32641 ctggtaatat ttgctgtcgc agccttagca gttgtcaaat agttgaggtt atcagggtct
    32701 gtctcataaa tgtatgagaa tgtcttctca cctttagtgc ttgaacctga tccagagcat
    32761 gcagctaaag tagtcgccgc caataatgtc acgcccgcaa gggcaaatag ttttgaactt
    32821 ttcatcattt tctcctttaa aactttctct ccattataga ctcttttcag aaagttgtca
    32881 acagaatttt cagaattttt gaaaattatt tttcaaacaa catctttgca aaaaatatga
    32941 atatcgtaag cgcgtcataa caaggtatct atcattcatg gagctcctcc tgtatactat
    33001 tagtaaagta aatattggag gatattttaa tgccacaacc tattgttcct gtagagattc
    33061 cacaatctcg tcgttttgat tctaaaaaga gaaatgatat tctacttaaa attcgtattg
    33121 gcaagcttga agtaagtttt tttcaatctc tcaatctcga aatgatagaa cagcttttgg
    33181 ataaggtgtt gctctatgac aattcatcta tctagcctag ggcaggtcta tctcgtgtgt
    33241 gggaaaactg atatgagaca aggaatcgat tcactggctt atctcgttaa aacccacttt
    33301 gaattggatc ctttctccgg tcaaatcttt ctcttttgtg gtggacgtaa agaccgcttt
    33361 aaagtccttt actgggatgg tcaaggattt tggctactat ataaacgctt tgagaacggc
    33421 agactgactt ggcccagtac agaaaaggat gtcaaagctc tcgcacctga acaagtagat
    33481 tggctgatga aaggcttttc tatcactcca aaaatatagt agattgaaac tagaatagta
    33541 cacctctgct tctaaaacat tgttagaaat cgattttact gtcctgatcg atttgtcctg
    33601 ttattatttc attttactat aaatccatca gaaagtcgtg atttctattg aaatgaggac
    33661 tttcttttta tactcatctg ctttcaaaaa gcactctaat taacgatgga ctttatcacc
    33721 tccttctcca gtccttgtat aacatcttga agttgattca tgacatcttc caaagttc
//
LOCUS       DAVFER010000023        33761 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1105170250
            SAMEA2167659-rid19724873.denovo.023, whole genome shotgun sequence.
ACCESSION   DAVFER010000023 DAVFER010000000
VERSION     DAVFER010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2167659
            Sequence Read Archive: ERR388902
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 33761)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33761)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928716.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928716.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 04:07:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,118
            CDSs (total)                      :: 2,073
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 120
            CDSs (without protein)            :: 120
            Pseudo Genes (ambiguous residues) :: 0 of 120
            Pseudo Genes (frameshifted)       :: 67 of 120
            Pseudo Genes (incomplete)         :: 47 of 120
            Pseudo Genes (internal stop)      :: 34 of 120
            Pseudo Genes (multiple problems)  :: 23 of 120
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33761
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2167659-rid19724873.denovo.023"
                     /strain="1105170250"
                     /db_xref="taxon:1313"
     gene            <1..379
                     /locus_tag="VU534_001147"
     CDS             <1..379
                     /locus_tag="VU534_001147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="histidine motif-containing protein"
                     /protein_id="HEU1513744.1"
                     /translation="RNKNGQADTNQTEKPSEEKPQTEKPEEETPREEKPQSEKPESPK
                     PTEEPEESPEESEEPQVETEKVEEKLREAEDLLGKIQDPIIKSNAKETLTGLKNNLLF
                     GTQDNNTIMAEAEKLLALLKESK"
     gene            801..1175
                     /locus_tag="VU534_001148"
     CDS             801..1175
                     /locus_tag="VU534_001148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002960428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS-dependent dihydroxyacetone kinase
                     phosphotransferase subunit DhaM"
                     /protein_id="HEU1513745.1"
                     /translation="MESIGLVIVSHSKHIAEGVVELISKVAKDVPITYVRGTEGGGIG
                     TSFEQVDRVVSENPADTLLAFFDLGSAKMNLKMVTDFSDKSIIINRVPIVEGAYNAAA
                     LLQAGAELSVIQTQLAELEINK"
     gene            1635..2348
                     /locus_tag="VU534_001149"
     CDS             1635..2348
                     /locus_tag="VU534_001149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000499426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjjG family noncanonical pyrimidine
                     nucleotidase"
                     /protein_id="HEU1513746.1"
                     /translation="MFYKFLLFDLDHTLLDFDAAEDVALTQLLKEEGVADIQAYKDYY
                     VPMNKALWKDLELKKISKQELVNTRFSRLFAHFGQEKDGSFLAQRYQFYLAQQGQTLS
                     GAHDLLDSLIERDYNLYAATNGITAIQTGRLAQSGLAPYFNQVFISEQLQTQKPDALF
                     YEKIGQQIAGFSKEKTLMIGDSLTADIQGGNNAGIDTIWYNPHHLENHTQAQPTYEVY
                     SYQDLLDCLDKNILEKITF"
     gene            2406..3008
                     /locus_tag="VU534_001150"
     CDS             2406..3008
                     /locus_tag="VU534_001150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1513747.1"
                     /translation="MSEVDFNEAVNYEFTSDTCQLANSIYQSLFKFFDKKNFSGDLIF
                     TWKSPSLVKEGDYIGRRDSQVDNLRVIGNIFPNYLTNRKYSLNMNRNGCMGDFPHDFF
                     DIYLDHVAKYAYEQKVNNIKEYYPLKRAILHQENALYFRFFSNFDDFLEKNYLKTIWQ
                     VSKETPFSEMDFNMFKNISEKIIFERGSKMLNDLKSNYKK"
     gene            3146..3799
                     /locus_tag="VU534_001151"
     CDS             3146..3799
                     /locus_tag="VU534_001151"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HEU1513748.1"
                     /translation="MEHSSWHALIKAQLPEGYFGKINQFMEQVYSQGIIYPPKEKVFQ
                     ALLTTLLEEVKVVILGQDPYHGPGQAQGLSFSVPDSIPAPPSLQNILKELSDDIGVKK
                     SHDLTAWAEQGVLLLNACLTVPAGQANGHAGQIWEPFTDAVIQVVNHLDRPVVFVLWG
                     AYARKKKALVTNPHHLIIESAHPSPLSVYRGFWGSKPFSKANAFLKETGQEPIDWLR"
     gene            3809..4273
                     /locus_tag="VU534_001152"
     CDS             3809..4273
                     /locus_tag="VU534_001152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003012002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HEU1513749.1"
                     /translation="MPQLATICYIDNGKELLMLHRNKKPNDVHEGKWIGVGGKLERGE
                     TPQECAAREILEETGLKAKPVLKGVITFPEFTPDLDWYTYVFKVTEFEGDLIDCNEGT
                     LEWVPYDEVLSKPTWEGDHTFVEWLLEDKPFFSAKFVYDGDKLLDTQVDFYE"
     gene            4286..5554
                     /locus_tag="VU534_001153"
     CDS             4286..5554
                     /locus_tag="VU534_001153"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HEU1513750.1"
                     /translation="MLLIKNGRVMDPKSGLDQVCDVLVQDGKIIKIASEITEEGAETI
                     DATGLVVAPGLVDIHVHFREPGQTHKEDIHTGALAAAAGGFTTVVMMANTSPTISDVE
                     TLQAVLQSAAKEKINVKTVATITKNFNGKNLTDFKALLEAGAVGFSDDGIPLESSKIV
                     KEAMEEAKKLNTFISLHEEDPGLNGVLGFNENIAREHFHICGATGVAEYAMMARDVMI
                     AYATKAHVHIQHLSKEESVKVVEFAQGLGAEVTAEVAPQHFSKTEALLLTQGSNAKMN
                     PPLRLESDRRAVIEGLKSGVITVIATDHAPHHVDEKNVEDITKAPSGMTGLETSLSLS
                     LTYLVEAGELSLMELLEKMTYNPAKLYNFEAGYLAENGPADITIFDAKADRFVDSHFA
                     SKAANSPFIGETLKGQVKYTICKGQIVYQA"
     gene            5568..5828
                     /locus_tag="VU534_001154"
     CDS             5568..5828
                     /locus_tag="VU534_001154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1513751.1"
                     /translation="MNYFRKRRERQAKSNSGIYCPAANRSKIQYETKEKADHAVQYDN
                     GGLVRSYYCRTCACWHTTSKSNKPPLSLKNYGLKLFGLDKSE"
     gene            5839..7200
                     /gene="pdrM"
                     /locus_tag="VU534_001155"
     CDS             5839..7200
                     /gene="pdrM"
                     /locus_tag="VU534_001155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000278543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-coupled multidrug efflux MATE transporter
                     PdrM"
                     /protein_id="HEU1513752.1"
                     /translation="MYKTKCLREKLVLFLKIFFPILIYQFANYSASFVDTAMTGQYNT
                     MDLAGVSMATSIWNPFFTFLTGIVSALVPIIGHHLGRGKKEEVASDFYQFIYLALGLS
                     VVLLGMVLFLAPIILNHIGLEAAVAAVAVRYLWFLSIGIIPLLLFSVIRSLLDSLGLT
                     KLSMYLMLLLLPLNSGFNYLLIYGAFGVPELGGAGAGLGTSLAYWVLLGISVLVLFKQ
                     EKLKALHLEKRIPLNMDKIKEGVRLGLPIGGTVFAEVAIFSVVGLIMAKFSPLIIASH
                     QSAMNFSSLMYAFPMSISSAMAIVVSYEVGAKRFDDAKTYIGLGRWTALIFAAFTLTF
                     LYIFRGNVASLYGNDPKFIDLTVRFLTYSLFFQLADTFAAPLQGILRGYKDTVIPFYL
                     GLLGYWGVAIPVATLFDSLTDFGAYSYWIGLIISLIVSGALYRWRLTVIMKRFESLAK
                     SKC"
     gene            7354..8322
                     /locus_tag="VU534_001156"
     CDS             7354..8322
                     /locus_tag="VU534_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine pyrophosphate-dependent dehydrogenase
                     E1 component subunit alpha"
                     /protein_id="HEU1513753.1"
                     /translation="MSTLDKNLLLEMFRKMEEIRRMDLKIAQLVKKGKVPGMTHFSVG
                     EEAANVGAMLALNPDDLITSNHRGHGQAIAKGIDLNGMMAEILGKYTGTCKGKGGSMH
                     IADLDAGNLGANGIVGGGMGIAVGAALSQQMQNTGKIVVCFFGDGATNEGVFHEAVNM
                     ASIWNLPVIFYCINNGYGISADIKKMTNIEHIHQRSAAYGIPGMFIEDGNNVIDVYEG
                     FQKAVDHVRSGNGPVLIESVTYRWLGHSSSDPGKYRTREEVELWKQKDPIENLRNYLI
                     ENNIASAEELEEIQAQVKEAVEASVKFAEESPFPPLESAFEDIYAD"
     gene            8338..9330
                     /locus_tag="VU534_001157"
     CDS             8338..9330
                     /locus_tag="VU534_001157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000448722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HEU1513754.1"
                     /translation="METKTMSFRDTIILAMSEEMRRDENVFLMGEDVGVFGGDFGTSV
                     GMLEEFGPERVRDCPISEAAISGAAAGAAMTGLRPIVDMTFMDFSVIAMDNIVNQAAK
                     TRYMFGGKGQVPMTVRCAAGNGVGSAAQHSQSLESWFTHIPGLKVVAPGTPADMKGLL
                     KSSIRDNNPVIILEYKSEFNQKGEVPVDPDYTIPLGVGEIKRQGTDVTVVTYGKMLRR
                     VVQAAEELAEEGISVEIVDPRTLVPLDKDIIINSVKKTGKVVLVNDAHKTSGYIGEIS
                     AIISESEAFDYLDAPIRRCAGEDVPMPYAQNLENAMIPTVESIKDAIRKTYNKE"
     gene            9548..10591
                     /locus_tag="VU534_001158"
     CDS             9548..10591
                     /locus_tag="VU534_001158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide acetyltransferase"
                     /protein_id="HEU1513755.1"
                     /translation="MADDKLRATPAARKLADDLGINLYDVSGSGANGRVHKEDVETYK
                     DTNVVRISPLAKRIALEHNIAWQEIQGTGHRGKIMKKDVLALLPENIENDSIKSPAQI
                     EKVEEVPDNVTPYGKIERIPMTPMRKVIAQRMVESYLTAPTFTLNYEVDMTEMLALRK
                     KVLEPIMEATGKKTTVTDLLSLAVVKTLMKHPYINASLTEDGKTIITHNYVNLAMAVG
                     MDNGLMTPVVYNAEKMSLSELVVAFKDVIGRTLDGKLAPSELQNSTFTISNLGMFGVQ
                     SFGPIINQPNSAILGVSSTIEKPVVVNGEIVIRPIMSLGLTIDHRVVDGMAGAKFMKD
                     LKELIETPISMLI"
     gene            10655..12340
                     /gene="lpdA"
                     /locus_tag="VU534_001159"
     CDS             10655..12340
                     /gene="lpdA"
                     /locus_tag="VU534_001159"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HEU1513756.1"
                     /translation="MPKAGVDMTEGQIVQWNKKVGEFVKEGEILLEIMTDKVSMELEA
                     EEDGYLIAILKGDGETVPVTEVIGYLGEERENIPTAGAASPEASPVPVASTSNDDGKS
                     DDAFDIVVIGGGPAGYVAAIKAAQFGGKVALVEKSELGGTCLNRGCIPTKTYLHNAEI
                     IENIGHAANRGIVIENPNFTVDMEKLLETKSKVVNTLVGGVAGLLRSYGVTVHKGIGT
                     ITKDKNVLVNGSELLETKKIILAGGSKVNKINVPGMESPLVMTSDDILEMNEVPESLV
                     IIGGGVVGIELGQAFMTFGSKVTVIEMMDRIVPAMDVEVSKNLRLILERKGMTILTGT
                     KLQEIIEENGQLRIKVEGKDDIIASKALLSIGRMPDLEGIGEVEFELDRGCIKVNEYM
                     ETSVPGIYAPGDINGTKMLAHAAFRMGEVSAENALKGNHAVAKLNLTPAAIYTLPEVA
                     AVGLTEEQAREKYDVAIGKFNFAANGRAIASDAAQGFVKVIADKKYGEILGVHIIGPA
                     AAELINEASSIIEMEITVEEMLKTIHGHPTYSEVMYEAFADVLGMAIHSPKKK"
     gene            12404..13393
                     /locus_tag="VU534_001160"
     CDS             12404..13393
                     /locus_tag="VU534_001160"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000873976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HEU1513757.1"
                     /translation="MKYIINHSNDTAFNIALEEYAFKHLLDEDQIFLLWINKPSIIVG
                     RHQNTIEEINRDYVRENGIEVVRRISGGGAVYHDLNNLNYTIISKEDENKAFDFKSFS
                     TPVINTLAQLGVKAEFTGRNDLEIDGKKFCGNAQAYINGRIMHHGCLLFDVDLSVLAN
                     ALKVSKDKFESKGVKSVRARVTNIINELPKKITVEKFRDLLLEYMKKEYPEMTEYVFS
                     EEELAEINRIKDTKFGTWDWNYGKSPEFNVRRGIKFTSGKVEVFANVTESKIQDIKIY
                     GDFFGIEDVAAVEDVLRGVKYEREDVLKALKTIDITRYFAGISREEIAEAVVG"
     gene            complement(13458..14528)
                     /gene="xerS"
                     /locus_tag="VU534_001161"
     CDS             complement(13458..14528)
                     /gene="xerS"
                     /locus_tag="VU534_001161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000817875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerS"
                     /protein_id="HEU1513758.1"
                     /translation="MKREILLERIDKLKQLMPWYVLEYYQSKLAVPYSFTTLYEYLKE
                     YDRFFSWVLESGISNADKISDIPLSVLENMSKKDMESFILYLRERPLLNANTTKQGVS
                     QTTINRTLSALSSLYKYLTEEVENDQGEPYFYRNVMKKVSTKKKKETLAARAENIKQK
                     LFLGDETEGFLTYIDQEHPQQLSNRALSSFNKNKERDLAIIALLLASGVRLSEAVNLD
                     LRDLNLKMMVIDVTRKGCKRDSVNVAAFAKPYLENYLAIRNQRYKTEKTDTALFLTLY
                     RGVPNRIDASSVEKMVAKYSEDFKVRVTPHKLRHTLATRLYDATKSQVLVSHQLGHAS
                     TQVTDLYTHIVSDEQKNALDSL"
     gene            complement(15112..16662)
                     /locus_tag="VU534_001162"
     CDS             complement(15112..16662)
                     /locus_tag="VU534_001162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
                     /protein_id="HEU1513759.1"
                     /translation="MEEQSEIVRSKKEFAFASSTILSQVGRGIIVGLIVGIIVGSFRF
                     LIEKGFHLIQGVYQDQGYLVRNLFVLVLFYILICWLSAKLTRSEKDIKGSGIPQVEAE
                     LKGLMSLNWWGILWKKYVLGILAIASGLMLGREGPSIQLGAVGGKGIAKWLKSSPVEE
                     RSLIASGAAAGLAAAFNAPIAALLFVVEEVYHHFSRFFWVSTLAASIVANFVSLLMFG
                     LTPVLDMPDNIPPMTLDQYWIYLVMGIFLGFSGFLYEKAVLNVGRVYDLIGQKIHLDR
                     AYYPILAFILIIPVGIFLPQIIGGGNQLVLSLTEQNFSFQVLLAYFLIRFIWSMISYG
                     SGLPGGIFLPILALGSLLGALVGVICVNLGLVSQEQFPIFVILGMSGYFGAISKAPLT
                     AMILVTEMVGDIRNLMPLGLVTLVSYIIMDLLKGTPVYEAMLEKMLPEEVSSEGEVTL
                     IEIPVSDKIAGKQVHELNLPHNVLITTQVHNGKSQTVNGSTRMYLGDMIHLVIPKSEI
                     GKVKDLLL"
     gene            complement(16678..17457)
                     /locus_tag="VU534_001163"
     CDS             complement(16678..17457)
                     /locus_tag="VU534_001163"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HEU1513760.1"
                     /translation="MATIKEIKEFLVTVKELESPIFLELEKDNRSGVQKEISKRKRAI
                     QAELDENLRLESMLSYEKELYKQGLTLIAGIDEVGRGPLAGPVVAAAVILSKNCKIKG
                     LNDSKKIPKKKHLEIFQAVQDQALSIGIGIIDNQVIDQVNIYEATKLAMQEAISQLSP
                     QPEHLLIDAMKLDLPISQTSIIKGDANSLSIAAASIVAKVTRDELLKEYDQQFPGYDF
                     ATNAGYGTAKHLEGLTKLGVTPIHRTSFEPVKSLVLGKKES"
     gene            complement(17444..18295)
                     /gene="ylqF"
                     /locus_tag="VU534_001164"
     CDS             complement(17444..18295)
                     /gene="ylqF"
                     /locus_tag="VU534_001164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HEU1513761.1"
                     /translation="MATIQWFPGHMSKARRQVQENLKFVDFVTILVDARLPLSSQNPM
                     LTKIVGDKPKLLILNKADLADPAMTKEWRQYFESQGIQTLAINSKEQVTVKVVTDAAK
                     KLMADKIARQKERGIQIETLRTMIIGIPNAGKSTLMNRLAGKKIAVVGNKPGVTKGQQ
                     WLKTNKDLEILDTPGILWPKFEDETVALKLALTGAIKDQLLPMDEVTIFGINYFKEHY
                     PEKLAERFKQMKIEEEAPVIIMDMTRALGFRDDYDRFYSLFVKEVRDGKLGNYTLDTL
                     EDLDGND"
     gene            complement(18514..18690)
                     /locus_tag="VU534_001165"
     CDS             complement(18514..18690)
                     /locus_tag="VU534_001165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001853125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEU1513762.1"
                     /translation="MQAGIPTDNEVSYDLIYQQETLPATGSSTSELTALGLLAVGSLV
                     FLVHNMTGTVFCSL"
     gene            complement(18742..24756)
                     /locus_tag="VU534_001166"
     CDS             complement(18742..24756)
                     /locus_tag="VU534_001166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000417171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HEU1513763.1"
                     /translation="MEKYFGEKQERFSFRKLSVGLVSATISSLFFMSVLASSSVDAQE
                     TAGVHYKYVADSELSSEEKKQLVYDIPTYVENDDETYYLVYKLNSQNQLAELPNTGSK
                     NERQALVAGASLAAMGILIFAVSKKKVKNKTVLHLVLVAGIGNGVLVSVHALENHLLL
                     NYNTDYELTSGEKLPLPKEISGYTYIGYIKEGKTTSESEVSNQKSSVATPTKQQKVDY
                     NVTPNFVDHPSTVQAIQEQTPVSSTKPTEVQVVEKPFSTELINPRKEEKQSSDSQEQL
                     AEHKNLETKKEEKISPKEKTGVNTLNPQDEVLSGQLNKPELLYREETMETKIDFQEEI
                     QENPDLAEGTVRVKQEGKLGKKVEIVRIFSVNKEEVSREIVSTSTTAPSPRIVEKGTK
                     KTQVIKEQPETGVEHKDVQSGAIVEPAIQPELPEAVVSDKGEPEVQPTLPEAVVTDKG
                     ETEVQPESPDTVVSDKGEPEQVAPLPEYKGNIEQVKPETPVEKTKEQGPEKTEEVPVK
                     PTEETPVNPNEGTTEGTSIQEAENPVQPAEESTTNSEKVSPDTSSKNTGEVSSNPSDS
                     TTSVGESNKPEHNDSKNENSEKTVEEVPVNPNEGTVEGTSNQETEKPVQPAEETQTNS
                     GKIANENTGEVSNKPSDSKPPVEESNQPEKNGTATKPENSGNTTSENGQTEPEPSNGN
                     STEDVSTESNTSNSNGNEEIKQENELDPDKKVEEPEKTLELRNVSDLELYSLSNGTYK
                     QHISLEQVPSNPNSYFVKVKSSSFKDVYLPVASISEERKNDKILYKITAKVEKLQQEI
                     ESRYKDNFTFYLAKKGTEETTNFTSFSNLVKAINQNPSGTYHLAASLNANEVELGPDE
                     RSYIKDTFTGRLIGEKDGKNYAIYNLKKPLFENLSGATVEKLSLKNVAISGKDDIGSL
                     ANEAQNNTKIKQVHVDGVLAGERGIGGLLAKAEQSSITESSFKGRIINTYETTAAYNI
                     GGMVGHLTGDKALLTKSKATVAISSNTNTSDQTVGGLAGLVDRDAQIQDSYAEGDINN
                     VKHFGRVAGVAGNLWDRTSGDVRHAGSLTNVLSDVNVTNGNAITGYHYNEMKVKDTFS
                     SKANRVYNVTLVKDEVVSKESFEERGTMLDASQIASKKAEINPLILPTVEPLSTSGKK
                     DSDFSKVAYYQAKRNLTYKNIEKLLPFYNKATIVKYGNLVNENSLLYQKELLSAVMMK
                     DNQVITDIVSNKQTANKLLLHYKDDLSEKLDLKYQNDFAKLAEYSLGNTGLLYTPNQF
                     LYDQTSIIKQVLPDLQKVDYHSEAIRKTLGISPNVKQTELYLEDQFAKTKQQLEDSLK
                     KLLSADAGLASANPVTEGYLVDKIKRNKEALLLGLTYLERWYNFSYGQVNVKDLVLYH
                     LDFFGKGNASPLDTLIELGKSGFNNLLAKNNVDTYGISLASQHGTTDLFSTLEHYRKV
                     FLPNTSNNDWFKSETKAYIVEEKSTIEEVKTKQGLAGTKYSIGVYDRITSATWKYRNM
                     VLPLLTLPERSVFVISTMSSLGFGAYDRYRSSDHKAGKALNDFVEENARETAKRQRDH
                     YDYWYRILDDNAREKLYRNILLYDAYKFGDDNTVGKATEVADFDNPNPAMQHFFGPVG
                     NKVGHNQHGAYATGDAVYYMGYRMLDKDGAITYTHEMTHDSDQDIYLGGYGRRSGLGP
                     EFFAKGLLQAPDHPDDATITINSILKHSKSDSTESRRLQVLDPTTRFNNADDLKQYVH
                     NMFDVVYMLEYLEGNSILKLDTNQKQQLLRKVTNEYHPDPDGNKVYATNVVRNLTVEE
                     VERLRSFNDLIDNNILSSREYASGKYERNGYFTIKLFAPIYAALSNDIGTPGDLMGRR
                     IAYELLAAKGFKDGMVPYISNQYEEEAKQKGKTINLYGKTRGLVTDDLVLEKVFNNQY
                     HTWSEFKKAMYQERQDQFDRLNKVTFNDTTQPWQTFAKKTTSSVDELQKLMDVAVRKD
                     AEHNYYHWNNYNPDIDSEVHKLKRAIFKAYLDQTNDFRSSIFENKK"
     gene            complement(24965..26143)
                     /locus_tag="VU534_001167"
     CDS             complement(24965..26143)
                     /locus_tag="VU534_001167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1513764.1"
                     /translation="MTLPVRKSLHDAVLQASKADTWEQATKEWNEVSFIFNGIGRSNC
                     VCGNAIKYAYELFNGVTGQRLFPIGSDCVRHFHRLSLDQQLEEEEKLLRKVENLTRKA
                     QKKEKIKVNKSNFDERLLKWLWEKGVFKPNRGNQFAPERDYQLFLEVFQGGSWTKAEP
                     KKKARMEEVLEKCIKPFLLGKSDDQLYLVKLGKEKIDYEQELRIQAEKERKKRDKIAK
                     QYADNLVLAMGPAERAYQDYFGFTETLTQEERKWEKILFGKNRAERAIKAKQYQKELE
                     KDQRIASQDPIERKQKQTWILNSYFRELPEEKARFSRLLLEYRKSGEVPFSTEYLSDH
                     LIDFFYKMKAFEFEIAPEQVRDFLKKSLQEDHRSSAQGSWIEGILLNCLKPFLERLVI
                     "
     gene            complement(26358..30008)
                     /gene="addA"
                     /locus_tag="VU534_001168"
     CDS             complement(26358..30008)
                     /gene="addA"
                     /locus_tag="VU534_001168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000767270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HEU1513765.1"
                     /translation="MKLIPFLSEEEIQKLQEAEANSSKEQKKTAEQIEAIYTSAQNIL
                     VSASAGSGKTFVMAERILDQLARGVEISQLFISTFTVKAATELKERLEKKISKKIQET
                     DDVDLKQHLGRQLADLPNAAIGTMDSFTQKFLGKHGYLLDIAPNFRILQNQSEQLILE
                     NEVFHEVFEAHYQGKQKETFSHLLKNFAGRGKDERGLRQQVYKIYDFLQSTSNPQKWL
                     SESFLKGFEKADFTSEKEKLTEQIKQALWDLESFFRYHLDNDAKEFAKAAYLENVQLI
                     LDEIGSLNQESDSQAYQAVLARVVAISKEKNGRALTNASRKADLKPLADAYNEERKTQ
                     FAKLGQLSDQIAILDYQERYHGDTWKLAKTFQSFMSDFVEAYRQRKRQENAFEFADIS
                     HYTIEILENFPQVRESYQERFHEVMVDEYQDTNHIQERMLELLSNGHNRFMVGDIKQS
                     IYRFRQADPQIFNEKFQRYAQNPQEGRLIILKENFRSSSEVLSATNDVFERLMDQEVG
                     EINYDNKHQLVFANTKLTPNPDNKAAFLLYDKDDTGEEEESQTETKLTGEMRLVIKEI
                     LKLHQEKGVAFKEIALLTSSRSRNDQILLALSEYGIPVKTDGEQNNYLQSLEVQVMLD
                     TLRVIHNPLQDYALVALMKSPMFGFDEDELARLSLQKAEDKVHENLYEKLVNAQKMAS
                     SQKGLIHTALAEKLKQFMDILASWRLYAKTHSLYDLIWKIYNDRFYYDYVGALPNGPA
                     RQANLYALALRADQFEKSNFKGLSRFIRMIDQVLEAQHDLASVAVAPPKDAVELMTIH
                     KSKGLEFPYVFILNMDQDFNKQDSMSEVILSRQNGLGVKYIAKMETGAVEDHYPKTIK
                     LSIPSLTYRQNEEELQLASYSEQMRLLYVAMTRAEKKLYLVGKGSREKLESKEYPAAK
                     NGKLNSNTRLQARNFQDWLWAISKVFTKDKLNFSYRFIGEDQLTREAIGELETKSPLQ
                     DSSQADNRQSDTIKEALEMLKEVEVYNTLHRAAIELPSVQTPSQIKKFYEPVMDMEGV
                     EIAGQGQSVGKKISFDLPDFSTKEKVTGAEIGSATHELMQRIDLSQQLTLASLTETLK
                     QVQTSQAVRDKINLDKILAFFDTVLGQEILANTDHLYREQPFSMLKRDQKSQEDFVVR
                     GILDGYLLYENKIVLFDYKTDRYDEPSQLVDRYRGQLALYEEALSRAYSIENIEKYLI
                     LLGKDEVQVVKV"
     gene            complement(30005..33280)
                     /gene="rexB"
                     /locus_tag="VU534_001169"
     CDS             complement(30005..33280)
                     /gene="rexB"
                     /locus_tag="VU534_001169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent nuclease subunit B"
                     /protein_id="HEU1513766.1"
                     /translation="MKLLYTDIRTSLTEILTREAEELVAAGKRVFYIAPNSLSFEKER
                     AVLEYLSQQASFSITVTRFAQMARYLVLNDLPAKTTLDDIGLGLAFYKCLAELDPKDL
                     RVYGAIKQDPQLIQQLIELYHEMTKSQMSFLDLENLTDEDKRADLLLIFEKVTAYLNQ
                     GQLAQESQLSHLIEAIENDKVSSDFNQIALVIDGFTRFSAEEERVVDLLHGKGVEIVI
                     GAYASKKAYTSPFSEGNLYQASVKFLHHLASKYQTPAQDCSQTHEKMDSFDKASRLLE
                     SSYDFSELALDVDEKDRENLQIWSCLTQKEELELVARSIRQKLHENSDLSYKHFRILL
                     GDVASYQLSLKTIFDQYQIPFYLGRSEAMAHHPLTQFVESILALKRYRFRQEDLINLL
                     RTDLYTDLSQSDIDAFEQYIRYLGINGLPAFQQTFTKSHHGKFNLERLNVLRLRILAP
                     LETLFASRKQKAEKLLQKWSVFLKEGAVTKQLQDLTTTLEAVEQERQAEVWKAFCHVL
                     EQFATVFAGSQVSLEDFLALLHSGMSLSQYRTIPATVDTVLVQSYDLIAPLTADFVYA
                     IGLTQDNLPKISQNTSLLTDEERQNLNQATEEGVQLLIASSENLKKNRYTMLSLVNSA
                     RKQLFLSAPSLFNESESKESAYLQELIHFGFRRREKRMNHKGLSKEDMGSYHSLLSSL
                     VAYHQQGEMSDTEQDLTFVKVLSRVIGKKLDQQGLENPAIPTSPSSKTLAKDTLQALY
                     PAKQEFYLSTSGLTEFYRNEYSYFLRYVLGLQEELRLHPDARSHGNFLHRIFERALQL
                     PNEDSFDQRLEQAIQETSQEREFEAIYQESLEAQFTKEVLLDVARTTGHILRHNPAIE
                     TIKEEANFGGKDQAFIQLDNGRSVFVRGKVDRIDRLKANGAIGVVDYKSSLTQFQFPH
                     FFNGLNSQLPTYLAALKREGEQNFFGAMYLEMAEPVQSLMAVKSLAGAVVEASKSMKY
                     QGLFLEKESSYLGEFYNKNKANQLTDEEFQLLLDYNAYLYKKAAEKILAGRFAINPYT
                     ENGRSIAPYVQQHQAITGFEANYHLGQARFLEKLDLADGKRLVGEKLKQAWLEKIREE
                     LNR"
     gene            complement(33480..33635)
                     /locus_tag="VU534_001170"
                     /pseudo
     CDS             complement(33480..33635)
                     /locus_tag="VU534_001170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710121.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
BASE COUNT         9662 a         6586 c         6912 g        10601 t
ORIGIN      
        1 aagaaacaaa aatggtcaag ctgataccaa tcaaacggaa aaaccaagcg aggagaaacc
       61 tcagacagaa aaacctgagg aagaaacccc tcgagaagag aaaccgcaaa gcgagaaacc
      121 agagtctcca aaaccaacag aggaaccaga agaatcacca gaggaatcag aagaacctca
      181 ggtcgagact gaaaaggttg aagaaaaact gagagaggct gaagatttac ttggaaaaat
      241 ccaggatcca attatcaagt ccaatgccaa agagactctc acaggattaa aaaataattt
      301 actatttggc acccaggaca acaatactat tatggcagaa gctgaaaaac tattggcttt
      361 attaaaggag agtaagtaaa ggtagcagca ttttctaact cctaaaaaca ggataggaga
      421 acgggaaaac gaaaaatgag agcagaatgt gagttctagt tctcattttt ttcatgaaaa
      481 tgtgcaaaat atagtagatt gaaactagaa tagtatacct ctacttctaa aacattgtta
      541 gaaatcgatt tgactgtcct gttcttattt cattttacta tatcttaaca gatagtgtaa
      601 ataaagataa actatttact ggctaattaa tcagttaaac actagttaag gagtaatgat
      661 gaaaaaaaga acaatactat tattgatggc cagtctgtta gctcttgtct taggagcatg
      721 tggtttcttg gacatattga tcctggatca ttctcatcag gattactctt tactgctatt
      781 ttagaaactg gggtggtttg atggaaagta ttggtcttgt tatcgtttca cattccaaac
      841 acattgcaga aggtgttgtt gaactgatta gtaaagtagc taaagatgtt ccgattactt
      901 atgtaagagg aaccgagggc ggaggaattg gaacgagttt tgaacaagta gatagggttg
      961 tttccgaaaa tccagcagat actttacttg ccttttttga cctaggttct gctaaaatga
     1021 acttaaaaat ggtgactgat ttcagtgata aaagtatcat catcaacagg gttccaattg
     1081 tagaaggtgc ctataatgca gctgctcttc ttcaggctgg tgcagaactg tcagttattc
     1141 aaacacagtt agcggagctt gaaatcaata aataaggaat tttactataa ctctttttat
     1201 agataagcta ttgattatct caactataaa atgttaagta aatgatttca aaatcagaaa
     1261 gggattgctt tatgcagttc ctttttattt taacaggagt gaaactatag tgtttctaaa
     1321 ttgtgaatca atcaaaactg attgtgatgg ggctattcta gctttagaaa ccttcaaaaa
     1381 ttaaaattta aggcaatcaa ttacttggaa gagtatgaaa gcatttagtt tataggaatt
     1441 ctaggtctag aattacatat atatatttat gaagacgggg tgttcgatag ttagtattgt
     1501 tctattctga aagatttgag ctgtcagttg tatagaaagt gttcgaattt ttttaagtga
     1561 ttaaattagt taattgtatg aggtgcttta tgatataatg ttcttaatga attttcagaa
     1621 aggaaaacct caaattgttc tacaaatttc tactcttcga cctcgaccac actcttcttg
     1681 attttgatgc tgctgaggat gtggctttga cccaacttct aaaagaagaa ggagttgcgg
     1741 atattcaggc ttataaagat tattacgttc ctatgaacaa ggctctctgg aaagacttgg
     1801 agctgaagaa aatcagtaaa caagagctgg ttaacacgcg cttttctcgt ttatttgctc
     1861 attttggaca ggaaaaagac ggtagttttc ttgcccagcg ttaccaattt tacctcgccc
     1921 agcagggaca aacactatcg ggcgctcatg atctcttgga cagcctcatt gagcgtgatt
     1981 ataacttgta tgctgcgaca aatggcatta ctgccattca gacaggacgt ttggctcaat
     2041 ctggtctagc accttatttc aatcaagtct ttatctcaga acagttgcaa actcaaaagc
     2101 cggatgctct tttttatgaa aagattggcc agcaaattgc tggatttagt aaagaaaaga
     2161 cgctgatgat tggagattct ctaaccgccg acattcaagg tggcaataat gcggggattg
     2221 acactatctg gtataatcct catcacctcg aaaatcacac acaagcccag ccgacttacg
     2281 aagtctattc ttaccaagac ttgctggatt gtttagataa aaatattctt gaaaagatca
     2341 cattttaaag gagacgagct aatgactaca aaaaagctaa tattactatt gaagagtaca
     2401 ttgaaatgtc tgaagttgat tttaatgaag ctgttaatta tgaatttaca tctgacactt
     2461 gtcaattagc aaatagtatt tatcaatctc tttttaagtt ttttgataag aaaaatttct
     2521 ctggcgattt aatttttact tggaaatctc catcattagt caaagaaggg gattatattg
     2581 ggagaaggga ttcacaagta gataatctta gagtaatagg aaatatattt ccgaattatc
     2641 ttactaatcg aaaatatagc ctcaatatga atcgtaatgg ctgtatggga gattttcctc
     2701 atgacttttt tgatatatac ctagatcatg tagcaaaata tgcctacgaa caaaaagtta
     2761 ataatattaa agagtattat cctttaaaaa gagcgatttt acaccaagag aatgcattgt
     2821 attttcgatt tttttctaat tttgacgact ttttagaaaa aaattattta aagactatat
     2881 ggcaagtttc taaagaaact cctttttctg agatggattt taatatgttt aaaaatattt
     2941 cagaaaagat aatcttcgaa agaggtagta aaatgcttaa tgatttaaaa agtaattata
     3001 aaaaatagcc agtctttata aactgtattc acgtattcaa atcgtatata tagtcgattt
     3061 attaaatctt tagataaact gtaaaaagtg gtttccatag ccactttttg ctataataga
     3121 ggcagtaaaa atgaaggagt cggctatgga acactcgtct tggcatgctt tgattaaggc
     3181 gcaattacct gagggttatt tcgggaaaat caatcagttt atggagcagg tctattctca
     3241 ggggattatt tatccaccca aggaaaaggt ttttcaggct ctcttgacaa cactgcttga
     3301 agaagttaag gtggtaattc tagggcaaga cccctatcac ggaccaggtc aagcgcaggg
     3361 cttgagtttt tctgtacctg actctatccc agctccacca tccttgcaaa atatcttgaa
     3421 agaattgtca gatgatatcg gagttaagaa atctcatgat ttgacagctt gggctgagca
     3481 aggagtcttg cttcttaatg cttgtttgac tgttcctgct ggacaggcca atggtcatgc
     3541 tggtcaaatc tgggagcctt ttactgatgc tgtgattcag gtggtcaatc atctagatag
     3601 accagtcgtt tttgtactct ggggagctta tgcacgtaag aagaaggcat tagttaccaa
     3661 tcctcatcac ttgattatcg aatcagccca tccaagtcct ttgtcggttt atagaggatt
     3721 ttggggttcc aagccctttt ccaaggccaa tgcattctta aaagagacag gacaagagcc
     3781 aatcgattgg cttagataag gagaaaatat gcctcagtta gcgacgattt gctacattga
     3841 taatgggaaa gaactgctca tgctccatcg taataagaaa cccaatgatg tccatgaagg
     3901 gaaatggatt ggtgtgggtg gtaagctaga gagaggagag acgccccagg aatgcgcggc
     3961 gcgtgaaatc cttgaagaaa cagggctcaa agccaagcca gttctaaaag gtgtcatcac
     4021 ttttcctgaa tttacaccag atttagactg gtacacctat gtttttaagg tgacggagtt
     4081 tgagggcgac ttgattgact gcaatgaggg gacgctagaa tgggttccct atgatgaggt
     4141 tttgagcaag ccgacttggg aaggtgacca cacctttgtt gagtggcttt tagaggataa
     4201 acccttcttt tcagccaagt ttgtttatga tggggataaa ttgttggata cccaagttga
     4261 tttctatgaa taaaggagaa agcagatgct actaatcaaa aatggtcgtg taatggatcc
     4321 caagtctggt ttggatcaag tttgtgatgt cttagttcaa gatgggaaaa ttatcaaaat
     4381 tgcgtctgag atcacggaag aaggagcaga aacgattgat gctactggtc ttgtggttgc
     4441 tcctggcttg gtcgatattc atgttcattt ccgtgaacct ggtcaaacac ataaagaaga
     4501 cattcatact ggtgccctag cagccgctgc aggtggtttt actactgtcg tcatgatggc
     4561 taataccagt ccaaccattt cagacgtgga gactttgcaa gcagttctcc agtcagctgc
     4621 caaagagaag attaatgtca agacagttgc gaccattact aaaaacttta atggtaaaaa
     4681 cttgactgac tttaaggcac tcttagaagc tggtgcggtt ggtttctctg atgacggtat
     4741 tccgcttgag agcagtaaga ttgtcaagga agccatggag gaagccaaaa aactcaatac
     4801 ctttatcagc cttcatgagg aagatccagg tttgaacggt gttcttggct ttaatgaaaa
     4861 tattgctaga gaacatttcc atatctgcgg tgctactggg gtggctgagt acgctatgat
     4921 ggcgcgtgat gtcatgattg cctatgcaac taaagcccat gttcacatcc agcatttgtc
     4981 taaggaagaa agtgttaaag tagtggagtt tgctcagggg ttaggtgcag aagtcacagc
     5041 agaagtagcg ccacagcatt tctctaagac agaagcactt cttttaacac aaggtagcaa
     5101 tgctaagatg aatccaccgc ttcgtttgga atcagaccgt cgtgccgtta tcgaaggtct
     5161 caaatcaggt gtcatcacag ttattgcgac tgaccacgcg cctcatcatg tagatgaaaa
     5221 aaatgttgag gatattacca aagcgccatc tggtatgact ggcttagaaa catccctgtc
     5281 tctcagcttg acctatttag tagaagctgg tgagttgagc ttgatggaat tacttgaaaa
     5341 aatgacatac aacccagcca agctttacaa ctttgaagca ggttacttgg ctgagaatgg
     5401 tccagcagat atcactattt ttgatgccaa ggctgaccgc tttgtggact cccattttgc
     5461 ttccaaagca gctaattcac cattcatcgg tgaaacctta aaagggcagg ttaaatatac
     5521 catctgtaag ggacaaatcg tctatcaagc ttgataggag ttagaatatg aattattttc
     5581 gaaaacgtag ggagagacaa gcgaaatcta atagtggaat ttactgtccc gcagctaatc
     5641 gttccaaaat tcaatatgaa actaaagaaa aagctgacca tgcggttcaa tatgataacg
     5701 gaggtttagt tagaagctat tattgtcgta catgtgcgtg ttggcatact acttcaaaat
     5761 ctaataaacc tccgctaagt ttgaaaaact atggtctgaa actctttggt ttagataaat
     5821 cagaatagaa agagaagtat gtataagaca aagtgtttac gagagaagtt agtattattt
     5881 ttaaaaattt tcttcccaat cctgatctac caatttgcca attattctgc ctcttttgtt
     5941 gatactgcaa tgacaggtca atacaacact atggacttgg ctggtgtatc tatggcaacc
     6001 agtatctgga atcctttctt tacatttcta acagggattg tgtcagcctt ggtgcctatc
     6061 attggtcacc atcttggtcg aggcaaaaag gaagaagttg cgtctgattt ttaccaattt
     6121 atttatttgg ccttgggcct atctgtggtc ttgctgggga tggtactttt cttggcacca
     6181 ataatcttga atcatattgg gttagaagca gcagtagcgg cagtagcggt tcgctatctt
     6241 tggtttttat ctatcgggat tatccccttg ttgctcttta gcgtcattcg ttccttgctg
     6301 gattcgctgg gcttgaccaa actgtccatg tacctcatgc ttttgttact ccctctcaat
     6361 agcggattta actatctctt gatttacggt gcctttggtg ttccagaact gggaggggct
     6421 ggtgctggtt taggaacatc cttggcctac tgggtcttgc ttgggatttc tgttctggtt
     6481 ttatttaaac aggagaagct caaagcctta caccttgaga aacgaattcc acttaatatg
     6541 gataaaatta aggaaggagt tcgtttaggt ctgcctattg ggggaactgt cttcgcggaa
     6601 gtggctatct tttcagtggt tggcttgatt atggctaagt tttcgccctt gattatagct
     6661 agtcaccagt cagctatgaa cttttcaagt cttatgtacg cctttcctat gagtatctca
     6721 tcggctatgg ctattgtcgt ttcctatgaa gtgggagcca agcgatttga tgatgcgaaa
     6781 acctatattg gtctaggaag atggactgcc ctcatttttg cggccttcac cttaaccttc
     6841 ctttacattt ttaggggaaa tgtggccagt ctttatggta acgacccaaa atttatcgat
     6901 ttgacagtgc gttttttaac ttatagtctt ttcttccagt tagcagatac ctttgcggcg
     6961 ccgcttcagg gaattttgcg ggggtataag gatacagtta ttccttttta ccttggtttg
     7021 cttggttatt ggggcgtagc aatccctgtg gctacgctat ttgattccct aacagatttt
     7081 ggagcttatt cttactggat cggcttgatt attagtttga ttgtgagcgg ggcgctctac
     7141 cgttggcgtt taactgtgat tatgaagaga tttgaatctt tagcaaaatc caaatgctaa
     7201 aaagtttgtg aaaaaatatt cttgacaaga aaatcccttg ttttcacggg gttttctttt
     7261 ttattttgtg aaatttcttt tagaaaaact ttgacagtat ttgccaaaag cggtaaaata
     7321 gtaaggtaag aagaaagtta gaaaggcaag aagatgtcaa ctttagataa aaatcttttg
     7381 ctagaaatgt tccgtaagat ggaagaaatc cgtcgcatgg acttaaaaat tgcacaatta
     7441 gtaaagaaag ggaaagtgcc aggaatgacg cacttttctg ttggtgaaga ggcagctaac
     7501 gtgggggcta tgttagctct caatccagat gatctgatta cctcaaacca ccgtggacac
     7561 gggcaagcta ttgctaaagg gattgacctc aacggaatga tggctgaaat ccttggtaaa
     7621 tacactggaa cctgtaaagg gaaaggtgga tctatgcata tcgctgacct tgatgctggg
     7681 aaccttggtg ccaatggtat cgtaggtggt ggtatgggga tcgctgtcgg tgcagccctc
     7741 agtcagcaaa tgcaaaatac cggtaaaatc gttgtctgct tctttggaga tggtgcgacc
     7801 aatgaaggtg ttttccacga agcagtgaac atggcttcta tctggaacct gccagtcatt
     7861 ttctattgca ttaacaacgg ttacggtatc tctgcggata tcaagaaaat gaccaatata
     7921 gaacatatcc atcaacgtag cgccgcttat ggaattcctg gaatgttcat cgaagacggt
     7981 aacaatgtca tcgatgtcta tgaaggattt cagaaagctg tggaccatgt tcgcagtggc
     8041 aatggtccag tcttgattga aagtgtaact tatcgctggc tcggtcactc atcatctgac
     8101 cctggtaaat atcgtacgcg tgaagaagtg gaattgtgga aacaaaaaga tccaatcgaa
     8161 aacctccgca attaccttat tgaaaataac attgcaagtg ccgaagaatt ggaagaaatc
     8221 caagcgcaag taaaggaagc agtagaagct tctgttaaat ttgcagagga aagcccattc
     8281 ccaccgcttg aatcagcctt tgaagatatt tacgcagact aaggagaaag agataaaatg
     8341 gaaacaaaaa caatgtcctt ccgtgacacc attatccttg ctatgtctga ggaaatgcgt
     8401 cgcgatgaaa atgtgttctt gatgggagaa gacgtcggtg tcttcggagg agacttcggt
     8461 acttctgttg gaatgcttga agaatttggt ccagaacgtg tccgtgactg tccgatttct
     8521 gaagctgcca tctctggagc agcagcagga gcagccatga caggacttcg tccaatcgtc
     8581 gatatgacct tcatggactt ctctgttatt gccatggaca atatcgtcaa ccaagctgct
     8641 aaaacacgtt acatgtttgg tggtaaaggt caggttccaa tgactgttcg ttgtgcagct
     8701 ggtaacggag ttggctctgc cgcccagcac tcacaatctc tagagtcttg gtttactcac
     8761 attccaggac ttaaggttgt ggcacctgga acacctgcgg acatgaaagg cctgcttaag
     8821 tcttctatcc gtgataacaa cccagttatt atacttgagt acaagtcaga atttaaccaa
     8881 aaaggggaag tgccagttga tccagactac acaattccac ttggggttgg tgaaatcaaa
     8941 cgccaaggaa cggatgtaac agttgttact tatggaaaaa tgcttcgccg tgtggttcaa
     9001 gctgctgaag aattagcaga agaaggaatt tcagttgaaa ttgttgaccc acgtaccctt
     9061 gttccgcttg ataaggatat catcataaac tcagtgaaga agactggtaa ggttgttctg
     9121 gtcaacgatg cccacaaaac aagtggctat atcggtgaaa tttcagctat tatttcagaa
     9181 tcagaagcat ttgactatct agatgcacca attcgccgtt gtgcaggaga agatgtgccg
     9241 atgccttatg cacaaaacct agaaaatgca atgattccaa cagttgaaag tatcaaagat
     9301 gcaatccgaa aaacttataa caaagaatag ggttacataa gataagttat gtaaataaaa
     9361 taaagctgac gagaaacttt gtatctttta ggtgcagagc tcttcgtcat taatatctta
     9421 gattagagca cgggctaaaa gatcggaaaa aagataaatc tccttggctt catcgaagcc
     9481 atcgtcgatt tcctattttt cagtcgcttt tgacgccctt tgtatcataa atagaattgg
     9541 agaggtcatg gctgatgaca agctaagagc gactcctgca gctagaaagt tagcggatga
     9601 tttagggata aacctctacg acgtttctgg ctcaggtgca aacggtcgtg tccacaaaga
     9661 agacgtggaa acttataaag acacaaacgt ggttcgcatt tcgccacttg caaaacgaat
     9721 tgccctcgaa cataacattg cttggcagga aatccaagga accggtcatc gtggtaaaat
     9781 catgaagaag gatgttttgg ccctgcttcc tgaaaatatc gaaaacgata gcatcaaatc
     9841 tcctgctcag attgaaaaag tggaagaagt ccctgataac gtaacaccat atggtaaaat
     9901 cgagcgtatt ccaatgacac caatgcgtaa ggttattgcc caacgcatgg ttgaatctta
     9961 cttgactgcg ccaaccttca ccctcaacta tgaagttgat atgactgaaa tgttggctct
    10021 tcgtaagaag gttcttgagc caatcatgga agcaactggg aagaagacta ctgtaacaga
    10081 ccttctttcg cttgcagttg ttaagactct tatgaaacac ccatacatca acgcttcatt
    10141 gacagaagat ggcaagacta ttatcactca caactatgtc aatcttgcca tggcagttgg
    10201 gatggataat ggattgatga cacctgttgt ttacaatgct gagaagatga gtctttcaga
    10261 actggttgta gcctttaagg atgttattgg ccgtaccttg gatggtaaat tggctccaag
    10321 tgagttacaa aattcaacat tcacaatcag taatttggga atgtttggtg ttcagtcctt
    10381 tggtccgatt attaaccaac ccaactcagc tatccttggt gtcagttcga caatcgagaa
    10441 gccagttgtc gtcaatggtg aaattgtgat tcgcccaatc atgagtttag gattaaccat
    10501 tgaccaccgt gtcgtagatg gtatggctgg tgctaagttt atgaaggact tgaaagagtt
    10561 gattgaaacg ccaatctcaa tgttaattta agagcaagag tattcatttt taagatatag
    10621 ataaaggaag gaagacatgg ccttagaagt aattatgcca aaagccggcg tggatatgac
    10681 agaaggacaa atcgtccaat ggaataaaaa agtcggagaa tttgtaaaag aaggagaaat
    10741 ccttttggaa atcatgactg ataaagtcag catggaattg gaagccgaag aagatgggta
    10801 cttgattgcc attctcaaag gagatggtga aactgtccct gtaacggaag ttatcggtta
    10861 ccttggtgaa gaaagggaaa acatcccaac agctggagca gcatcgccag aagctagccc
    10921 tgtacctgta gcaagtacct caaacgatga tggtaagagc gatgatgctt ttgatatcgt
    10981 tgtgattggt ggaggtcctg ctggttatgt tgcagccatt aaagctgccc aattcggcgg
    11041 taaggttgcc cttgttgaga aatctgaact tggtggaacc tgcttaaacc gtggatgtat
    11101 tccaaccaag acctaccttc ataacgctga aattattgaa aatatcggtc atgctgcaaa
    11161 tcgtggtatc gtgattgaaa atcctaactt cactgttgat atggaaaaac ttttagaaac
    11221 taaatctaaa gttgttaata ctcttgttgg tggtgttgca ggacttcttc gtagctacgg
    11281 agttactgtt cataaaggaa ttggtacaat cactaaagac aagaacgtct tggtaaatgg
    11341 ttctgaattg cttgaaacca agaaaatcat tcttgctggt ggttcaaaag tcaacaagat
    11401 caacgtccct ggtatggaat ctccacttgt catgactagt gatgacattc ttgaaatgaa
    11461 cgaagtgcca gaaagccttg ttatcatcgg tggtggagtt gtcggtatcg aactcggtca
    11521 ggccttcatg acatttggtt caaaagtgac tgttatcgaa atgatggacc gtatagttcc
    11581 agctatggat gtggaagttt ctaagaacct tcgcttgatt cttgagcgta aaggaatgac
    11641 catcttgact ggtactaaac tgcaagaaat cattgaggaa aatggtcaac ttcgtatcaa
    11701 ggttgaagga aaagacgata tcatcgcaag caaagctctt ctttcaattg gtcgtatgcc
    11761 agaccttgaa ggtattggag aggttgagtt tgaattggat cgtggttgta tcaaggtcaa
    11821 cgaatacatg gaaacttcag ttccaggcat ttatgcacca ggtgacatca acggtactaa
    11881 gatgttggct cacgcagctt tccgcatggg tgaagtttcc gctgaaaatg cccttaaagg
    11941 aaatcatgca gttgccaaat tgaatttgac tcctgcagcc atctacactc tccctgaagt
    12001 agcagcagta ggtttgacag aagaacaagc ccgtgagaaa tacgatgttg ccatcggtaa
    12061 gtttaacttt gctgctaacg gtcgtgctat tgcatctgac gcagctcaag gtttcgtaaa
    12121 agttatcgct gataagaaat acggagaaat ccttggtgta cacattattg gtcctgcagc
    12181 cgcagaatta ataaacgaag catcaagcat catcgaaatg gaaatcactg ttgaggaaat
    12241 gctgaagacc atccacgggc acccaactta ctctgaagtg atgtacgaag cgtttgcaga
    12301 tgttctagga atggccatcc attcacctaa gaaaaaataa aacgaagata gattagactg
    12361 gaaggttatt tccagtttct atcatataaa gtaaagggat atcatgaaat acattatcaa
    12421 tcattcaaat gacactgctt ttaatattgc cttggaagaa tacgccttta aacacctttt
    12481 ggatgaggat caaatcttcc tactttggat taacaagcca tctatcattg ttggtcgtca
    12541 ccagaacact atcgaagaaa tcaaccgtga ttatgttcgc gaaaatggta ttgaggtagt
    12601 tcgccgtatt agtggtggtg gagctgttta ccacgattta aataacctca actacacgat
    12661 catctccaaa gaagatgaaa ataaggcatt tgacttcaag agcttctcaa ctccggttat
    12721 caataccctg gctcaacttg gggttaaagc tgagttcaca ggtcgtaatg accttgagat
    12781 tgatggtaag aagttctgtg gcaatgccca agcctatatc aacggccgta tcatgcacca
    12841 cggttgcttg ctctttgacg ttgatttgtc agtcctcgca aatgccctta aggtttcaaa
    12901 agataaattt gaatcaaaag gtgtgaaatc cgtccgtgcc cgtgtaacca atattatcaa
    12961 tgaattacca aaaaaaatca cagtcgaaaa attccgtgat ttactcttgg aatacatgaa
    13021 aaaagagtac ccagagatga ctgaatacgt cttttcagaa gaagaattgg ccgaaatcaa
    13081 tcgcatcaag gatactaagt ttggaacttg ggactggaac tatggtaaat cacctgaatt
    13141 taacgtccgt cgtggaatca aattcactag tggtaaggtt gaagtctttg ctaacgttac
    13201 tgaatcaaaa atccaagaca tcaagattta tggtgacttc tttggtattg aagacgttgc
    13261 tgcagtagaa gatgtccttc gtggggtgaa atacgaacgc gaagatgttc ttaaggcgct
    13321 aaaaaccatt gatatcacac gctacttcgc tggtattagc cgtgaagaaa tcgctgaagc
    13381 ggtagttgga taaatcaaaa agaagttggc caacttcttt ttttgatatt tatttacata
    13441 atttaaaata cgtaaaatca taaactatcc agagcattct tttgttcatc actaacaata
    13501 tgggtataga ggtcagtgac ttgtgtgcta gcatgtccta gttggtgact gactaaaact
    13561 tgtgatttag tcgcatcata gagcctagtt gctagtgtat ggcgcagttt atggggtgtt
    13621 acacgcactt taaaatcctc tgagtattta gcaaccattt tctcaacgct agaagcatcg
    13681 atacgattag gaacacctct gtagagagtt aaaaaaaggg ctgtatctgt tttttccgtt
    13741 ttatagcgtt gattccgaat ggccagataa ttctctaaat aaggtttagc aaaagcagcg
    13801 acattgactg agtcacgttt gcaacctttt cgagtaacat caataaccat catttttaga
    13861 ttgagatctc ttagatctag attaacagct tcagataagc gaacaccaga tgccaagaga
    13921 agggcaataa tggctaaatc tcgttcttta tttttgttga atgatgagag agctcgattt
    13981 gaaagctgtt gtgggtgctc ttgatcgata taagttagaa aaccttctgt ttcatcacct
    14041 agaaagagtt tttgcttgat attttcagct ctggcagcaa gggtttcttt ctttttcttg
    14101 gtggaaactt ttttcattac attacgatag aaataaggtt ccccctgatc gttttcaacc
    14161 tcctcggtta gatacttgta aagactagaa agtgctgata aggttcgatt gatagttgtc
    14221 tgtgaaacac cttgttttgt tgtattagca ttcagcaagg gacgttcacg tagataaagg
    14281 ataaaggatt ccatgtcttt cttagacata ttttccaaaa ctgataaagg aatatcggat
    14341 attttatcag cgtttgaaat accagactcc aaaacccagc tgaaaaatcg gtcatattcc
    14401 ttaaggtatt cgtacagggt tgtaaaactg tagggcacag ccagcttaga ttggtagtat
    14461 tccagaacat accagggcat gagttgtttt agtttgtcga ttcgttccag taaaatctca
    14521 cgtttcatgt attttctcca taagtaagta tactagtagt atagcataga cttgtatatt
    14581 tttcaagaaa attatagttt ttcggaaaga tgttatagga gtttttcaaa gtgataaaaa
    14641 gacttagacc tacaaacaaa acagaataag gaaaataata aaaatctcac ccactaaact
    14701 tctgttaata ctacataact gaagagctat ataaggagct atgagataca aaacacattg
    14761 tataatagat tgaaactaga atagtacatc tggacttcta aaacattgct agaaattgat
    14821 ttgattgtcc tgattgtttt atcctatttc tatttcattt ctctatataa ttgctattgt
    14881 tttctttttc atgattttaa tcttactgta cagatttgat acagtaaact cctttctagc
    14941 tttatacttt atcatttcta acttaattat agtcttattt ttaataaagt tcaattattt
    15001 atatgtaaaa ttcctcatca gtaaaaaata accgatctca ttcctgagaa tcggttttct
    15061 aaataaatca aactgatcat ttacataaca taaattatgt aaatactcat actacaacaa
    15121 caaatctttg acttttccaa tttcactttt tggaataacc aggtgaatca tatcacccag
    15181 atacattctg gttgagccgt taactgtttg gctcttgcca ttatggactt gagttgtgat
    15241 gaggacgttg tgtggtaagt tgagttcatg aacttgtttc ccagcaattt tatcagaaac
    15301 tggtatttcg ataagtgtaa cttctccttc gctagatact tcttctggaa gcattttttc
    15361 cagcatggct tcatagactg gcgtaccttt gagcaaatcc atgataatat aagaaacaag
    15421 agtgacaaga ccaagtggca taaggttgcg aatatctcct accatctcag ttacgaggat
    15481 catagcggtt aagggagctt ttgatatggc tccaaaatag ccactcattc ctagaatgac
    15541 aaatataggg aattgctctt gactgacaag tccaagattg acacagataa caccaactaa
    15601 ggcaccaagc aaagaaccaa gagctaaaat ggggaggaaa attcctcctg gcagtccact
    15661 tccatagcta atcatactcc aaataaagcg gattaaaaag taagctaata aaacttggaa
    15721 actaaaattt tgttcagtta aagaaaggac aagctgattt ccgccaccaa tgatttgagg
    15781 taagaagatt ccgactggta tgataaggat aaaagccaag atgggataat aagccctatc
    15841 caaatggatt ttttgaccaa tcaagtcata aactcttcca acgtttaata cagctttctc
    15901 atagagaaaa cctgaaaatc caaggaaaat tcccatgacg agatatatcc aatactgatc
    15961 tagggtcatg ggaggaatgt tatctggcat atccaatact ggtgtcaaac cgaacatgag
    16021 tagagacaca aagtttgcta cgatgctggc tgctagagtt gagacccaga aaaagcgcga
    16081 aaaatggtga tagacttctt ctacaacaaa gagaagtgct gcaataggag cattaaaggc
    16141 tgcggctaaa cctgctgcag ctccactggc aatcaaggaa cgttcctcta ctggactgga
    16201 tttgagccac ttggcaattc ctttaccacc aactgctcca agttgaatgc tgggtccctc
    16261 tcgacccagc atgagtccac tggcaatagc aagaatacct agcacatatt ttttccaaag
    16321 aatgccccac cagttgaggg acatgaggcc tttcagttcg gcttcgactt gaggaattcc
    16381 tgagccttta atatcttttt ctgaccgtgt tagtttggca ctgagccaac agatgagtat
    16441 ataaaacaaa accagtacaa aaagattgcg cactaagtac ccttgatctt gataaactcc
    16501 ttgtatcagg tggaagccct tttcaattaa gaaacgaaag gatccgacga taattccaac
    16561 gatgaggccg acaatgattc ctcgaccaac ttgggatagt atagtgctgg atgcaaaggc
    16621 gaattctttc ttagaacgga ctatttccga ctgttcctcc atgttatttc ctttcaatta
    16681 actttctttt ttacctaaaa ccagtgattt aacgggttca aagctggttc ggtgaattgg
    16741 ggtaactcct agttttgtga ggccttccag atgtttagct gtgccatatc ctgcattagt
    16801 agcgaaatca tagccaggga actgctgatc gtattctttc agcaattcat cacgtgttac
    16861 cttggctact atagatgctg ctgcgataga gagggagttg gcatctcctt tgataatgga
    16921 ggtttgtgaa atgggcaagt ccagtttcat ggcatcaatc aaaaggtgct ctggttgagg
    16981 gctgagctgg gagattgctt cttgcatggc tagtttggtt gcttcataga tgttgacttg
    17041 gtcgatgacc tgattatcta tgataccaat tccaatcgac aaggcttggt cttgaacggc
    17101 ttggaaaatc tccagatgtt tctttttagg aattttcttg ctgtcgttga gacctttaat
    17161 cttacaattt ttagataaaa taacggccgc agcgactaca ggaccagcaa gaggaccacg
    17221 accaacctca tcaatacctg caattaaggt caatccttgc ttataaagtt ctttttcata
    17281 agaaagcatg gattccaagc gcaaattttc atctaattca gcttgaatgg ctcttttacg
    17341 cttgctgatt tccttttgaa ctcctgagcg attatccttt tcaagctcta aaaaaatagg
    17401 gctttctaac tccttgactg tcacaaggaa ttctttgatt tctttaatcg ttgccatcga
    17461 ggtcttccaa tgtatctaag gtatagttac cgagtttgcc atcacggact tccttcacga
    17521 agagactgta aaaacggtca tagtcatcac ggaaaccgag ggcgcgggtc atatccataa
    17581 taatcacagg cgcttcttct tcaattttca tttgtttgaa gcgttcagcc agcttttctg
    17641 gataatgttc tttgaaataa ttgataccaa aaatggtaac ctcatccata ggaagcaact
    17701 ggtctttgat agctccagtc aatgccaact taagtgcaac agtttcatcc tcaaacttag
    17761 gccagagaat ccccggtgta tccaagattt ccaggtcttt attggtttta agccattgtt
    17821 gaccttttgt gacccctggc ttgtttccaa caacagcaat ctttttacca gccaaacggt
    17881 tcatcagagt tgatttacca gcgtttggaa tcccgataat catagtacgc aaggtttcaa
    17941 tctgaatccc acgttctttc tggcgagcaa tcttatcagc catgagcttc ttggccgcat
    18001 ctgttacaac ttttacagtc acttgctctt tggagttgat agctagcgtc tggattcctt
    18061 gtgattcaaa atactgacgc cattccttgg tcattgctgg atcagccaag tcggccttgt
    18121 ttaaaatcaa gagttttggt ttatcaccaa caatcttggt caacatagga ttttgactag
    18181 atagaggcaa gcgtgcatct actaaaatcg tcacaaaatc aacaaatttt aaattctcct
    18241 gcacctgtcg acgagcttta gacatgtgac caggaaacca ttgaatagta gccattgagt
    18301 tttttccttt catagcaagg atttagatcc cctattttat tttactattg tttgaacata
    18361 gagagttttc aaatgaatga tgtccaaaca gttcttgttt tatgacatag aaatctactt
    18421 tatattatat catgccttct ttattttgtc cgatgatagc cttttaccct atcttttacc
    18481 ctatatagaa aaaagccatc aaatgatgac ttttcagagg gagcaaaaaa ctgttcccgt
    18541 catattatga accaaaaaaa ctaaactacc aacagctaat aggcctaaag ctgtaagctc
    18601 agaagttgat gaacctgttg caggaagagt ttcctgctga taaataagat cataacttac
    18661 ttcattatca gtaggaattc ctgcttgaat cttggtttgt tcttcatcac ctttttaaac
    18721 tttatttcct aatagtagac actatttttt attctcaaaa attgaacttc taaaatcatt
    18781 tgtttggtca agataggctt taaagattgc tctcttgagc ttgtggactt cactatctat
    18841 gtctggattg tagttattcc aatggtagta attgtgttct gcatccttac gaacagcaac
    18901 gtccattaat ttctgtaatt catctacact gcttgtagtt ttcttggcaa atgtttgcca
    18961 aggctgtgtt gtatcattaa aagtaacttt gttcaatcta tcaaactgat cttgtcgttc
    19021 ttgatacata gctttcttaa actcactcca agtatgatat tggttattaa ataccttttc
    19081 caaaaccaag tcatctgtaa ccaaacctct tgttttaccg tagagattga ttgtcttgcc
    19141 cttttgtttg gcttcttctt cgtattggtt tgagatatat ggtaccatac catctttaaa
    19201 gcctttagca gctagtagtt cataggctat acgacgtccc atcaggtcac ctggtgttcc
    19261 tatatcatta cttaatgcag cataaatcgg tgcaaataac ttaatagtga agtagccatt
    19321 tctttcgtat ttacctgagg catattccct agacgaaaga atattattat caatcaaatc
    19381 attgaatgaa cgtagtcttt caacttcttc tactgttaga tttctgacaa catttgttgc
    19441 atagacctta tttccatcag gatcaggatg gtactcattt gtaacttttc taagaagttg
    19501 ttgtttttga ttcgtatcca atttaagaat tgaatttcct tcgagatatt ccaacatata
    19561 aacaacgtca aacatgttgt ggacatattg cttcaaatca tctgcattat taaatcttgt
    19621 agttggatca agtacttgta atcgtcgact ttctgtacta tcagattttg aatgtttcaa
    19681 gatggagttg atggtaatgg tcgcatcatc tggatggtct ggtgcttgta ataatccttt
    19741 agcaaagaac tctggtccca agccacttct tcgaccatat cctccaagat aaatgtcctg
    19801 atctgagtca tgtgtcatct catgcgtata agtaatagct ccatccttat ccaacattcg
    19861 ataacccata taataaactg catcacctgt agcataagca ccgtgttgat tatgcccaac
    19921 tttatttcca acaggtccaa agaaatgttg cattgcagga tttggattat caaaatctgc
    19981 cacttctgta gctttcccta cggtattatc atcgccaaat ttataagcat cgtaaagcaa
    20041 aatatttcta taaagttttt cacgtgcatt gtcgtctaaa atacgatacc aataatcgta
    20101 gtgatctcgc tgacgtttgg ctgtttcacg cgcattttct tcaacaaaat cattgagagc
    20161 cttgcccgct ttatggtcac tactgcggta gcgatcataa gctccaaatc ctagactaga
    20221 catggtcgag atgacaaata cggatctctc tggcaaggtc aggagaggca agaccatatt
    20281 gcggtatttc catgtggcac tcgtgatacg atcataaaca ccgatagaat acttggtgcc
    20341 agctaaccct tgcttcgttt tcacctcttc gatagtggat ttttcttcga caatgtaagc
    20401 cttagtctct gatttaaacc agtcattatt gcttgtattt ggtaaaaaga cttttcggta
    20461 atgttccagc gtgctaaaca aatctgtcgt tccatgttga ctggcaagac tgataccata
    20521 agtatcgaca ttattcttag ctagaagatt gttaaagcca gatttaccca actcaatcag
    20581 agtatctaat ggtgaagcat tccccttacc aaagaagtcc aaatggtaca gaactaggtc
    20641 tttgacattc acctgaccat agctaaagtt ataccaccgt tccagatagg tcaagccaag
    20701 tagcaaggct tccttgttgc gtttgatttt atctacaaga taaccttcag tgacggggtt
    20761 agcactagcc agtccagcat ccgctgacaa gagttttttc aaactgtctt ccagttgttg
    20821 ttttgttttg gcgaactggt cttctagata gagctcagtt tgcttgacgt ttggagaaat
    20881 acccagcgtc tttctgatgg cttctgaatg atagtcaacc ttttgtaagt caggtaagac
    20941 ttgcttgatg atagaggttt ggtcatacag gaattggttt ggcgtataga gaagtccagt
    21001 attgcccaga ctatattctg ctaatttggc gaaatcattc tggtatttga gatccagctt
    21061 ctcagataaa tcatccttgt agtgaagcaa gagtttgttt gcagtctgtt tgttagaaac
    21121 aatgtctgtg atgacttggt tgtccttcat catgactgct gacaagagtt ctttttgata
    21181 taaaagactg ttctcattga ccaggtttcc gtatttgacg atggttgcct tgttgtagaa
    21241 aggtagcaat ttttcaatgt ttttataagt caagttgcgc ttagcttgat aataggccac
    21301 cttagaaaaa tcactgtctt ttttgccact tgttgaaagt ggctccactg ttggtagaat
    21361 gagaggattg atttctgctt ttttgcttgc aatttgagaa gcatctagca ttgttcctct
    21421 ttcttcaaag gattccttgc tgacgacctc atccttgacc aaggtgacat tgtagactct
    21481 gttggccttg ctgctgaatg tgtcctttac cttcatttcg ttatagtggt aaccagtgat
    21541 ggcatttccg ttggttacat taacatcgct gagaacattg gtcaaacttc cagcatgcct
    21601 aacatcacca gaagttcgat cccacaaatt gcctgccact ccagcgactc taccaaagtg
    21661 cttgacattg ttgatatcac cttcagcata gctatcttgg atctgtgcat ctcggtctac
    21721 taggcctgca agtccaccca cagtctgatc tgaagtattt gtgttagatg aaatggctac
    21781 tgtcgctttt gacttagtaa gtaaagcctt gtcacctgtc aaatgaccga ccataccacc
    21841 gatattgtag gcagcagtcg tttcataagt gttgataatt cttcccttga aactgctctc
    21901 tgtgatgctt gattgctcag ccttagccag caaaccaccg ataccacgtt caccagccag
    21961 aacaccatcg acgtgaactt gcttaatttt tgtgttattc tgagcttcat ttgccagtga
    22021 accgatatca tctttccctg aaatagcaac attttttaga ctcagttttt ctactgtagc
    22081 accactcaag ttttcaaaca gaggtttttt caaattatag atagcataat tcttgccatc
    22141 tttttcaccg attaaacgac cagtaaaggt gtccttgata taggatcttt catcaggacc
    22201 aagctccact tcgttagcat tcaggctggc cgctaaatga taggttccag agggattttg
    22261 gtttatagct ttgaccagat tactaaagga agtaaagttt gttgtttctt ctgttccctt
    22321 cttagctaga tagaaggtaa aattatcttt atatctgctt tctatctcct gctgaagctt
    22381 ctctactttt gctgtgattt tataaaggat tttatcattt tttctttcct ctgatattga
    22441 tgctactggt aggtatacat ctttgaatga agaagatttc actttaacaa agtagctatt
    22501 tggattgctt ggaacttgct ctaacgaaat gtgttgttta taagtaccat ttgacaaact
    22561 gtataactct aggtcggaaa catttcttaa ttcaagtgtt ttctctggtt cttctacctt
    22621 tttatcaggg tctagttcat tttcttgttt aatttcttcg tttccatttg aattggatgt
    22681 gtttgattcg gttgaaacat cctcagttga atttccgttt gatggttctg gttctgtttg
    22741 tccattctct gatgttgtat tacctgaatt ttctggtttt gttgcagttc cgtttttttc
    22801 tggttgattt gattcttcaa ctggtggttt tgaatcacta ggtttattgg atacttctcc
    22861 agtattttcg ttagctattt tcccagagtt tgtttgtgtt tcttctgcag gttgaactgg
    22921 tttttctgtt tcttgatttg aggtaccttc tactgtgcct tcatttggat ttactggaac
    22981 ttcttctaca gttttttctg aattttcatt tttagagtca ttatgttctg gtttatttga
    23041 ttctccaact gaggttgtcg aatcactagg attactggac acttccccag tatttttgct
    23101 agatgtatct ggtgatactt tctctgaatt cgttgttgat tcttctgcag gttgaactgg
    23161 attttctgct tcttgaattg aggttccttc tgtagtacct tcatttggat ttactggtgt
    23221 ttcttctgtt ggttttactg gaacttcttc agttttttct ggaccttgtt ctttggtctt
    23281 ctcaaccgga gtttcaggtt ttacttgctc aatattaccc ttatattctg gaagcggtgc
    23341 tacctgctct ggttcacctt tatcacttac cacagtatct ggcgactctg gttgaacctc
    23401 agtctcacct ttgtcggtca caactgcttc gggtaatgta ggttgaactt ctggttcgcc
    23461 tttgtcactt actacagctt cgggcaactc aggctgaatt gcgggttcaa caatagctcc
    23521 agactgtacg tccttatgtt ctacaccagt ctcaggttgt tcctttataa cttgagtttt
    23581 tttagtacct ttttcgacta ttcttggact aggcgcagtc gttgaagttg aaacaatttc
    23641 tcgcgaaact tcttccttgt ttacagagaa tattctgacg atttcaactt tcttacctaa
    23701 tttaccttct tgttttactc ttacagttcc ttcagctaaa tcaggatttt cttgaatttc
    23761 ttcttgaaaa tctatttttg tctccatagt ttcctcacga tataagagtt caggtttgtt
    23821 caattgacct gataaaactt catcctgtgg atttaatgta tttaccccag tcttttcttt
    23881 tggagaaatc ttctcctctt tcttcgtttc tagattctta tgttcggcta attgttcttg
    23941 agaatctgaa gattgtttct cttcttttct tggattgatt aattcagtag agaaaggttt
    24001 ttcaactact tgaacttctg tcggcttagt tgaagaaaca ggtgtttgtt cctgaatagc
    24061 ttgtactgtt gatggatggt ctacaaaatt cggtgtaaca ttataatcca ccttttgttg
    24121 ttttgtagga gtggcaactg aactcttttg attacttact tcagactcag aagtcgtttt
    24181 tccctctttg atatatccaa tataagtgta acctgaaatc tctttaggaa gaggtaattt
    24241 ttctccagag gtcaattcat agtccgtatt gtaatttagc aaaagatgat tttctaaagc
    24301 atggactgaa actaagacac catttcctat ccctgcaacc aatactaaat gtaataccgt
    24361 tttattctta acctttttct tggaaacagc aaaaattaaa attcccatag cagctaagct
    24421 agcaccagca actagggctt gcctctcatt cttgcttcca gtatttggca attccgccag
    24481 ttgattttga gaatttaact tataaacaag ataataagtt tcatcatcat tctccacgta
    24541 tgtcggaata tcatagacaa gctgcttctt ttcttctgat gatagctctg aatctgccac
    24601 atatttatag tgaactcccg cagtttcttg agcatccaca gatgaactag ctaatacaga
    24661 cataaaaaat aaacttgaaa tcgttgcaga tacaagtcct actgataatt ttctaaatga
    24721 aaaacgctct tgtttttcac caaaatactt ttccattatt cctccttgaa ataaaattta
    24781 tatatgttac aaagaccttt attatattag tgtattatct attatctata gaaaaggcag
    24841 tataccttaa ttatactctt aatttacaaa aaagtcttaa aattgagatg cgctttcata
    24901 ctttgtttta tattatttgg aggtacaata acacctacca tgaaatttac acggtaggtg
    24961 ttactcatat cactaatcgt tctaaaaatg gtttgaggca gttgaggaga attccttcta
    25021 tccagcttcc ttgtgctgat gagcgatggt cttcctgcag gctttttttt agaaaatctc
    25081 ggacttgttc tggtgcgatt tcaaattcaa aggctttcat tttatagaaa aagtcgatga
    25141 gatgatctga caggtattca gttgaaaagg gtacttcacc actttttcta tattctaata
    25201 agagtctaga aaatcgagct ttttcttcag gaagctcacg aaaataggaa ttgaggatcc
    25261 aagtctgctt ctgttttctt tcaattggat cctgactggc aattcgttgg tctttttcca
    25321 gctctttttg gtattgtttg gccttgatag ctcgttctgc tctattttta ccaaaaagaa
    25381 ttttttccca cttgcgttct tcttgagtca gggtctctgt aaagccaaag taatcttgat
    25441 aagcacgctc tgcgggtccc atggctagaa ccagattgtc tgcatattgc ttggcgattt
    25501 tatccctctt cttgcgttct ttctctgcct ggatacggag ttcttgttcg tagtcaattt
    25561 tctccttgcc tagcttgaca aggtagagtt ggtcatccga tttcccaagt aaaaagggtt
    25621 tgatacactt ttcaaggact tcttccatcc gagccttttt ctttggttcc gccttggtcc
    25681 aacttcctcc ctgaaagact tctaggaaaa gctggtagtc tctctcaggc gcaaattgat
    25741 tgccacgatt gggtttgaaa acaccttttt cccagagcca ttttagaagt cgctcgtcaa
    25801 agttactttt attgaccttg attttttcct ttttctgagc ttttctggtt agattttcaa
    25861 cctttctgag cagtttttct tcctcttcca attgctggtc aagggacaat cgatgaaaat
    25921 gacgaacaca gtcgctacca attggaaaga ggcgttggcc tgtgacaccg ttaaagagtt
    25981 cataagcgta tttgatggca tttccacaga cacaattgct acggccgata ccgttaaaaa
    26041 taaaggaaac ttcattccat tccttggtag cttgttccca agtatccgct ttcgaagcct
    26101 gtaaaactgc atcgtgcagg gattttctaa ctggaagtgt catgaggtct cctttctaat
    26161 actcaataaa aatcaaagag caaactagaa agctagccgc aatcagctca aaacactgtt
    26221 ttgaggttgt agatagaact gacgaagtca gctcaaaaca ctgttttgag gttgtggata
    26281 gaactgacga agtcagtaac catatataca gcaaggcgaa gctgacgtgg tttgaagaga
    26341 ttttcaaaga gtataagtta tacttttaca acttgaacct cgtctttacc gagtaaaatc
    26401 aagtattttt caatattttc aatcgaatag gctcgtgata aagcctcttc gtatagagct
    26461 aactgaccac gatagcggtc tacgagttga cttggttcat catagcggtc tgtcttgtag
    26521 tcgaacagaa caattttgtt ttcgtaaagc agatagccat caaggatacc acggacaaca
    26581 aagtcttcct gactcttttg gtctcgtttg agcatggaga aaggttgctc gcgataaaga
    26641 tggtcggtat tagcaagaat ttcctgaccg agtactgtgt caaagaaagc aagaatttta
    26701 tcaagattga tcttgtctct gacagcttgg ctagtttgaa cttgtttgag tgtttctgtt
    26761 aggctagcaa gggttagttg ctggctgagg tcaattctct gcatgagttc gtgagtagca
    26821 ctaccaatct cagctccagt taccttttct ttggttgaaa aatctggcaa atcgaagctg
    26881 attttcttgc ctactgactg accttgacca gcaatctcga caccttccat atccataact
    26941 ggttcgtaga atttcttgat ttgacttggg gtttgaacac taggaagttc aatagctgcg
    27001 cggtgaagag tattataaac ttccacctcc ttcagcattt ccagagcttc tttgatggta
    27061 tctgactgac gattgtctgc ttgggagcta tcttggagag gactcttggt ttccaactct
    27121 ccgatagctt ctctggtcaa ctgatcttcg ccaataaaac gataactaaa gttgagcttg
    27181 tccttagtaa acactttact gatagcccaa agccaatctt ggaaattccg tgcttgcagt
    27241 ctagtattgc tatttagttt cccatttttg gctgctgggt attccttgga ttccagcttt
    27301 tcacgagaac ccttgccgac aagatagagc tttttctcag cccgcgtcat agcaacatac
    27361 agcaaacgca tctgctcaga atagcttgct agctgtaatt cctcttcgtt ctgcctatag
    27421 gtcagactag gaatggagag tttgatggtt ttaggatagt ggtcttctac tgcccctgtc
    27481 tccatcttgg caatatattt gacaccaaga ccattctgac gactgagaat gacttctgac
    27541 atagagtctt gcttgttgaa atcttgatcc atattgagga taaagacgta aggaaactcc
    27601 agccctttac tcttgtggat ggtcatgagc tctactgcat cttttggcgg tgcgacggcc
    27661 acgcttgcca aatcgtgctg ggcttctaag acttggtcaa tcatacgaat aaaacgcgac
    27721 aaacctttga aattgctctt ttcaaattga tcagcacgca gtgctagggc atagagattg
    27781 gcctgcctag caggaccatt cggcaaagcc ccaacatagt cataataaaa acggtcgttg
    27841 taaatcttcc aaatcaagtc atagagagag tgggttttgg catacaagcg ccaagaagct
    27901 aggatatcca tgaattgctt tagtttttca gctagagctg tgtgaatcaa gcctttttga
    27961 ctacttgcca ttttttgtgc attgaccagt ttctcataga gattttcgtg gactttatcc
    28021 tctgctttct gaagggacaa acgtgctagc tcatcctcat caaaaccaaa cattggagac
    28081 ttcataaggg caaccaaggc gtagtcttgc aggggattgt gaatgacacg aagagtgtct
    28141 agcatgactt gcacttctag ggattggaga taattgtttt gctctccgtc agttttgaca
    28201 ggaattccgt actcagacag ggcgaggaga atctggtcat tacgactgcg gctggaggtc
    28261 agaagggcaa tttccttaaa ggcaacacct ttttcttgat gaagtttcag aatctccttg
    28321 ataactaagc gcatttcgcc tgttagtttc gtttctgttt gactctcttc ttcctcacct
    28381 gtatcgtcct tgtcgtagag gagaaatgct gccttgttgt ctggattggg agtcagtttg
    28441 gtattggcaa aaacaagctg gtgcttgtta tcatagttga tttcgccgac ctcttggtcc
    28501 atgagacgtt caaagacatc attggttgct gacagcactt ctgaactact acggaaattt
    28561 tccttgagga taatgagcct gccttcttgg ggattttgcg catagcgttg gaatttctca
    28621 ttgaaaatct gcgggtctgc ctgacggaaa cgatagatgg attgcttgat atctcccacc
    28681 ataaagcgat tgtggccatt agacaacaat tccagcatcc gttcttgaat atggttggta
    28741 tcctgatact catcgaccat gacttcatgg aagcgctcct gataagactc acgaacttgt
    28801 gggaaattct ctaaaatctc aatggtgtaa tggctgatat cagcgaattc gaaggcattt
    28861 tcctgtcgtt ttctctgacg ataagcctct acaaaatcgc tcatgaaaga ttggaaggtt
    28921 ttagctagtt tccaagtgtc tccatgataa cgttcttgat agtcgagaat cgctatctgg
    28981 tctgataatt gtcctagttt agcaaactgg gtctttctct cttcgttgta ggcatcagcc
    29041 aggggcttca aatcagcctt acggctggca ttagtcagag ctcgaccgtt tttctcctta
    29101 gagatggcga caacacgcgc aagcactgcc tgataagcct gactatcgga ctcctgattt
    29161 agggagccaa tttcatccag aattaactga acattttcta aataggcagc ctttgcaaac
    29221 tccttggcat cgttatccag atggtaacgg aaaaagcttt ccaaatccca aagggcttgt
    29281 ttgatttgct cggtcagttt ttctttttca ctggtaaaat cagctttctc aaatcctttg
    29341 aggaaagatt cactcagcca cttttgagga ttactggtgg attggaggaa gtcatagatt
    29401 ttatagacct gctggcgcag accccgttcg tccttgccac gcccagcaaa gtttttcagc
    29461 aaatgactaa aggtctcttt ctgtttacct tggtaatgcg cttcaaagac ctcatgaaag
    29521 acttcgtttt cgagaataag ttgctcgctt tggttttgta aaatacggaa attaggtgca
    29581 atatcaagca gataaccatg tttgccaagg aatttttgtg tgaaagaatc catggttcca
    29641 atggcagcgt tgggtaggtc tgccaactgg cgacccaagt gttgtttgag gtcgacatca
    29701 tctgtttctt ggattttctt gctgattttt ttctctaaac gttctttaag ttcagttgca
    29761 gccttgacgg taaaggttga gataaagagt tgagaaattt cgacaccacg cgccaattgg
    29821 tccagaatgc gctctgccat gacaaaggtc tttccagaac cagccgatgc tgagaccagg
    29881 atattctggg cagaagtgta gatagcttcg atttgctcgg cagttttctt ctgttccttg
    29941 ctcgaatttg cttctgcttc ttgcagtttt tgaatctcct cctcacttaa aaagggaata
    30001 agcttcatcg attcaactcc tctcttattt tttcaagcca agcttgcttg agtttttctc
    30061 cgaccagacg cttgccatca gctaggtcca acttttctag gaaacgggct tggcccagat
    30121 ggtaattggc ttcaaagcct gtaatagcct gatgttgctg gacgtatggg gcaatgcttc
    30181 tgccattttc agtataagga ttgatggcga accggcctgc taaaatcttc tcagcagctt
    30241 tcttgtaaag ataggcattg tagtccagta ggagctgaaa ttcctcatct gtcagttgat
    30301 tagccttgtt tttgttataa aattcgccta aataactgct ttctttttcc aagaagagcc
    30361 cttggtattt catagatttg ctggcttcta ccactgctcc tgccagactt tttaccgcca
    30421 tcagagattg gacaggttca gccatttcca agtacatggc gccgaaaaag ttctgctccc
    30481 cttctctttt tagggcagca agataggttg gtaactgaga attgagccca ttaaagaaat
    30541 gaggaaactg gaactgagtc agactggatt tgtagtctac tactcctatc gctccattag
    30601 ctttcaaacg gtcaatccgg tccaccttgc ctcgtacaaa gacactgcgt ccattgtcta
    30661 attgaataaa ggcttggtct tttccaccaa aatttgcttc ttctttgatg gtttcgatgg
    30721 ctggattgtg tcggagaata tgtccagttg tccgtgcaac atcaagcaaa acttccttgg
    30781 taaactgggc ttccaaactt tcttgataaa tagcttcaaa ttcgcgttct tgactggttt
    30841 cttgaatagc ttgttctaga cgttggtcaa aggaatcttc attaggcaac tgtaaggcgc
    30901 gttcaaagat acgatgcaag aaattcccgt gactacgggc atcaggatgc aaacgtaatt
    30961 cctcctgcaa gcctaaaacg tagcgtagga aataactgta ttcattgcga taaaactctg
    31021 tcaaacccga cgtagacagg taaaactcct gtttggcagg atagagagct tgcaaggtgt
    31081 ccttggctaa ggtcttgctg cttggactgg ttgggatagc tggattttcc agaccttgct
    31141 gatctagttt tttacctatg acacgcgaca gaaccttgac aaaagtcaaa tcttgctcag
    31201 tatcgctcat ctcaccctgc tggtgatagg caaccagact agacaaaaga ctgtgatagg
    31261 accccatatc ctccttagac agtcctttgt gattcatcct cttctctctc cgcctaaatc
    31321 caaaatggat caactcttga agataggcag attccttact ttcactttcg ttaaaaaggc
    31381 ttggagccga caagaacaac tgcttacgag cagaattgac caaggaaagc atagtgtagc
    31441 gatttttctt gagattttca ctgctggcaa tcagtaattg aacgccttct tcggtcgctt
    31501 ggtttaggtt ttgcctttct tcatctgtca gaagactggt gttttgagaa atttttggta
    31561 aattgtcctg agttagtcca atagcataga caaagtcagc agtcaatggt gcaatcaaat
    31621 cgtaactctg caccagaaca gtgtccactg ttgctggaat ggtacggtat tgggacaaac
    31681 tcattccaga atggagcaag gctaggaagt cttccagact aacctgtgaa ccagcaaaaa
    31741 cagtcgcaaa ttgttctaaa acatggcaga aagccttcca aacttcggct tgtctttcct
    31801 gttctacagc ttccaaagtg gttgtcaaat cttgtaactg cttggtcaca gctccttctt
    31861 ttagaaagac actccatttt tgtaggagtt tttcagcctt ttgttttcgg ctggcaaaga
    31921 gggtttcaag aggtgctaaa attctcaggc ggaggacatt caaacgctca agattaaatt
    31981 ttccatggtg ggatttggtg aaggtttgct gaaaggctgg caagccattg ataccaagat
    32041 agcggatata ttgctcaaaa gcatcaatat cagactgact gaggtcagta tacaaatcag
    32101 ttctaagaag attaatcaaa tcctcctgac gaaaacggta acgttttaaa gctaaaatag
    32161 actcgacaaa ctgagtcaag ggatgatgag ccatggcttc gcttctacca agataaaaag
    32221 gaatctgata ctggtcaaaa atggttttga gagataactg gtaagaagct acatccccca
    32281 agagaatacg aaaatgcttg tagctcaggt ctgagttctc atgtaatttc tgacgaatac
    32341 tacgggctac tagctccaac tcctcctttt gcgtcaaaca agaccagatt tgtaaatttt
    32401 cacggtcttt ctcatcgaca tccaaagcga gttctgaaaa gtcataagaa gactccaaca
    32461 aacgagaggc cttgtcaaaa ctatccatct tctcatgagt ttgagaacag tcctgagcag
    32521 gcgtttggta tttagaagcc agatgatgga gaaattttac gctggcttgg tagagattgc
    32581 cctcgctaaa aggactggta taggctttct tactagcata agccccgata acaatctcaa
    32641 cacctttgcc gtgaagtaag tccacaaccc gctcttcctc agcagaaaaa cgagtaaagc
    32701 cgtcaatgac caaggcgatt tgattaaaat cactacttac cttgtcattc tcaatagcct
    32761 caatcaaatg ggacaactga ctttcctggg ctaactgacc ttgattaaga taggctgtta
    32821 ctttctcaaa aatcaagagt aaatccgccc tcttatcctc atctgttaaa ttctccaagt
    32881 ccaaaaaact catctgagat ttggtcatct catggtaaag ctcaattaac tgctggatca
    32941 attgaggatc ctgcttaata gcgccataaa cacgcaagtc cttgggatcg agttcggcaa
    33001 ggcatttgta aaaggccaac ccaagaccga tatcatcaag agtagtttta gctggtaaat
    33061 cattcaagac cagatagcga gccatttgag caaagcgcgt gacggtaatc gaaaaagaag
    33121 cctgctggga caagtattcc agcacggcgc gttccttttc aaaagaaaga gagttggggg
    33181 caatgtagaa gacccgcttg ccagctgcaa ctagctcttc tgcctctctt gttagaattt
    33241 ctgtcaaaga agtccgaata tcagtataaa gtaatttcat ctcagcctcg ttggaatttt
    33301 tcatcaccct atattatacc atgattagcc tcgtaaatct gttaaaatat ttaggccatc
    33361 ctttcttttc ttcatcatct gctaaatctt aaatacttag ctttacttgt attagataga
    33421 ataagtctgg ctactgaaaa tcacataata aaaaagcctc ggtaacaagg ctttgagttt
    33481 tatgattgtt tcttaggtac ggaatacact tcaatgtgtt gtcccagtat cttaatgtcg
    33541 actggtagat tgtctgattt atcgccatca acatcggact ctaattcgat atcagaagaa
    33601 gttttaatat tacgtgcctt tatatattca atattcttga tagaatgatt gaactatagt
    33661 aaattgaaac tataatagta caccgtggat gctaaaatat ttctagaaat taatttgatt
    33721 tccctaatca agctattcgt atcttatttc aatctactat a
//
LOCUS       DAVFER010000024        28815 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1105170250
            SAMEA2167659-rid19724873.denovo.024, whole genome shotgun sequence.
ACCESSION   DAVFER010000024 DAVFER010000000
VERSION     DAVFER010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2167659
            Sequence Read Archive: ERR388902
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 28815)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28815)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928716.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928716.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 04:07:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,118
            CDSs (total)                      :: 2,073
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 120
            CDSs (without protein)            :: 120
            Pseudo Genes (ambiguous residues) :: 0 of 120
            Pseudo Genes (frameshifted)       :: 67 of 120
            Pseudo Genes (incomplete)         :: 47 of 120
            Pseudo Genes (internal stop)      :: 34 of 120
            Pseudo Genes (multiple problems)  :: 23 of 120
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28815
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2167659-rid19724873.denovo.024"
                     /strain="1105170250"
                     /db_xref="taxon:1313"
     gene            complement(322..939)
                     /locus_tag="VU534_001171"
     CDS             complement(322..939)
                     /locus_tag="VU534_001171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HEU1513767.1"
                     /translation="MSQDKQMKAVSPLLQRVINISSIVGGVGSLIFCIWAYQAGILQS
                     KETLSAFIQQAGIWGPPLFIFLQILQTVVPIIPGALTSVAGVFIYGHIIGTIYNYIGI
                     VIGCAIIFYLVRLYGAAFVQSVVSKRTYNKYIGWLDKGNRFDRFFIFMMIWPISPADF
                     LCMLAALTKMSFKRYMTIIILTKPFTLVVYTYGLTYIIDFFWQML"
     gene            complement(1354..1548)
                     /locus_tag="VU534_001172"
                     /pseudo
     CDS             complement(1354..1548)
                     /locus_tag="VU534_001172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155340.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            complement(2058..2138)
                     /locus_tag="VU534_001173"
                     /pseudo
     CDS             complement(2058..2138)
                     /locus_tag="VU534_001173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            2255..3148
                     /locus_tag="VU534_001174"
     CDS             2255..3148
                     /locus_tag="VU534_001174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU1513768.1"
                     /translation="MLEVRSLEKSFGSKQVLFGIDFQARPGRILGLVGKNGAGKTTIF
                     HSILKFLEYQGEIGLDGQDIRQETYARIGYLPEERSLMPKLTVLEQVRYLATLKGMDA
                     KEVKEKLPQWMKRLEVKGKLTDKIKSLSKGNQQKIQLIITLIHEPDLIILDEPFSGLD
                     PVNTELLKQVIFQEKERGATIIFSDHVMTNVEELCDDILMIRDGRVVLHGPVQDVRNQ
                     YGKTRLFVSSERSKEELENLPHVKQVSLTKQGSWKLILEDESAGRELFSILTQGQYIA
                     TFDQQAPTIDEIFKLESGVEV"
     gene            3145..4344
                     /locus_tag="VU534_001175"
     CDS             3145..4344
                     /locus_tag="VU534_001175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001245382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU1513769.1"
                     /translation="MRNMWVVIKETYLRHVESWSFFFMVISPFLFLGISVGIGHLQGS
                     SMAKNNKVAVVTTVPSVAEGLKNVNGVNFDYKDEASAKEAIKEEKLKGYLTIDQEDSV
                     LKAVYHGETSLENGIKFEVTGTLNELQNQLNRSTASLSQEQEKRLAQTIQFTEKIDEA
                     KENKKFIQTIAAGALGFFLYMILITYAGVTAQEVASEKGTKIMEVVFSSIRASHYFYA
                     RMMALFLVILTHIGIYVVGGLAAVLLFKDLPFLAQSGILDHLGDAISLNTLLFILISL
                     FMYVVLAAFLGSMVSRPEDSGKALSPLMILIMGGFFGVTALGAAGDNLLLKIGSYIPF
                     ISTFFMPFRTINDYAGGAEAWISLAITVIFAVVATGFIGRMYASLVLQTDDLGIWKTF
                     KRALSYK"
     gene            complement(4756..5523)
                     /locus_tag="VU534_001176"
     CDS             complement(4756..5523)
                     /locus_tag="VU534_001176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000498762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1513770.1"
                     /translation="MFWNLVRYEFKNVNKWYLALYAAVLVLSALIGIQTQGFKNLPYQ
                     ESQATMLLFLATVFGGLMLTLGISTIFLIIKRFKGSVYDRQGYLTLTLPVSEHHIITA
                     KLIGAFIWSLISTAVLALSAVIILALTAPEWIPLSYVITFVETHLPQIFLTGISFLLN
                     TISGILCIYLAISIGQLFNEYRTALAVAVYIGIQIVIGFIELFFNLSSNFYVNSLVGL
                     NDHFYMGAGIAIVEELIFIAIFYLGTYYILRNKVNLL"
     gene            complement(5540..6235)
                     /locus_tag="VU534_001177"
     CDS             complement(5540..6235)
                     /locus_tag="VU534_001177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU1513771.1"
                     /translation="MSLLVFENVSKSYGATPALENVSLDIPAGKIVGLLGPNGSGKTT
                     LIKLINGLLQPDQGRVLINDMDPSPATKAVVAYLPDTTYLNEQMKVKEALTYFKTFYK
                     DFNLERAHHLLADLGIDENSRLKKLSKGNKEKVQLILVMSRDARLYVLDEPIGGVDPA
                     ARAYILNTIINNYSPTSTVLISTHLISDIEPILDEIVFLKDGKVVRQGNVDDIRYESG
                     ESIDQLFRQEFKA"
     gene            complement(6240..6605)
                     /locus_tag="VU534_001178"
     CDS             complement(6240..6605)
                     /locus_tag="VU534_001178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEU1513772.1"
                     /translation="MSWTFDNKKPIYLQIMEKIKLQIVSHTLEPNQQLPTVRELASEA
                     GVNPNTIQRALSDLEREGFVYSKRTTGRFVTKDKELIAQSRKQLSEEELEHFVSSMTH
                     FGYEKEELPGVVSDYIKGV"
     gene            6745..7218
                     /gene="nrdR"
                     /locus_tag="VU534_001179"
     CDS             6745..7218
                     /gene="nrdR"
                     /locus_tag="VU534_001179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001203675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor NrdR"
                     /protein_id="HEU1513773.1"
                     /translation="MRCPKCGATKSSVIDSRQAEEGNTIRRRRECDECQHRFTTYERV
                     EERTLVVVKKDGTREQFSRDKIFNGIIRSAQKRPVSSDEINMVVNRIEQKLRGRNENE
                     IQSEDIGSLVMEELAELDEITYVRFASVYRSFKDVSELESLLQQITQSSKKKKER"
     gene            7219..8388
                     /locus_tag="VU534_001180"
     CDS             7219..8388
                     /locus_tag="VU534_001180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000802368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation and membrane attachment
                     family protein"
                     /protein_id="HEU1513774.1"
                     /translation="MKPIDRFSYLKNNRVSQDTSSLVQCYLPIIGQEALSLYLYTISF
                     WDNGRKEYLFSSILNHLNFGMDRLIKSLKILSAFNLLTLYQKGDVYQLALHAPLSSQD
                     FLGHPVYRRLLEKKIGDVAVEDLKVESADGEEIPVSLNQVFPELAELGSQEDLGLKKK
                     VANDFDLEHFRQLMARDGLRFADEQSDVLNLFAIAEEKKWTWFETYQLAKSTAVSQVI
                     STKRMREKIAQKPVSSDFSLKEATIIKEAKSKTALQFLAEIKQTRKGTITQTERELLQ
                     QMAGLGLLDEVINIILLLTFNKVDSANINEKYAMKVANDYAYQKIHSAEEAVLRIRDR
                     GQKAKTQKQNQTAPEKTNVPKWSNPEYKNETSEETRLELERKKQELLARLEKGGD"
     gene            8389..9285
                     /gene="dnaI"
                     /locus_tag="VU534_001181"
     CDS             8389..9285
                     /gene="dnaI"
                     /locus_tag="VU534_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HEU1513775.1"
                     /translation="MESVGDVLKRQPSRFYYQDLVQKIMKDPDVAAFIQQESLTPKEL
                     NRSISKFNQYITERDKFLRGDTDYIAKGYKPILVKNHGYADVSYEETPELIAAEKEAA
                     IKNRLKLINLPASLKKASLAQVDLDDLGRLPVFEKLLAFVEQYPAIRKGLYLYGDFGV
                     GKSFMVAALAHDLSEKRGVSSTLLHYPSFVIDVKNAISDGNVKTLVDEIKLSEVLILD
                     DIGAEQSTVWVRDEILQVILQYRMQENLPTFFTSNFNFEDLEKHFAKVKHGNDETWEA
                     RRVMERIRYLAEETRLEGVNRR"
     gene            9282..9995
                     /locus_tag="VU534_001182"
     CDS             9282..9995
                     /locus_tag="VU534_001182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent oxidoreductase"
                     /protein_id="HEU1513776.1"
                     /translation="MTETIKLMKAHTSVRRFKEQEIPQVDLNEILTAAQMASSWKNFQ
                     SYSVIVVRSQEKKDALYELVPQEAIRQSAVFLLFVGDLNRAEKGARLHTDTFQPQGVE
                     GLLISSVDAALAGQNALLAAESLGYGGVIIGLVRYKSEEVAELFNLPDYTYSVFGMAL
                     GVPNQHHDMKPRLPLENVVFEEEYQEQSTEAIQAYDRVQADYAGARATTSWSQRLAEQ
                     FGQAEPSSTRKNLEQKKLL"
     gene            10009..11319
                     /gene="der"
                     /locus_tag="VU534_001183"
     CDS             10009..11319
                     /gene="der"
                     /locus_tag="VU534_001183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HEU1513777.1"
                     /translation="MALPTIAIVGRPNVGKSTLFNRIAGERISIVEDVEGVTRDRIYA
                     TGEWLNRSFSMIDTGGIDDVDAPFMEQIKHQAEIAMEEADVIVFVVSGKEGITDADEY
                     VARKLYKTHKPVILAVNKVDNPEMRNDIYDFYALGLGEPLPISSVHGIGTGDVLDAIV
                     ENLPNEYEEENPDVIKFSLIGRPNVGKSSLINAILGEDRVIASPVAGTTRDAIDTHFT
                     DTDGQEFTMIDTAGMRKSGKVYENTEKYSVMRAMRAIDRSDVVLMVINAEEGIREYDK
                     RIAGFAHEAGKGMIIVVNKWDTLEKDNHTMKNWEEDIREQFQYLPYAPIIFVSALTKQ
                     RLHKLPEMIKQISESQNTRIPSAVLNDVIMDAIAINPTPTDKGKRLKIFYATQVATKP
                     PTFVIFVNEEELMHFSYLRFLENQIRKAFVFEGTPIHLIARKRK"
     gene            11408..11743
                     /locus_tag="VU534_001184"
     CDS             11408..11743
                     /locus_tag="VU534_001184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1513778.1"
                     /translation="MEHLFKFLLLAPYFYFDNWIEKANRNSKFFPIFYYFYWFYIPFY
                     SLFSLAWTVVSVLFFNTVLRNVTDIKLWGIWFLFILLAIGMNWLTYSCFKEMFRLRQE
                     LGKSKGGRH"
     gene            11883..12218
                     /locus_tag="VU534_001185"
     CDS             11883..12218
                     /locus_tag="VU534_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1513779.1"
                     /translation="MEHLFKMIILLPCFYFFSWIDKDNRESKFFPIFYYFYWIYITLY
                     ALFSLAWTVFSVLFFNIVLRNLTDIKLWGIWLLLLLIAFASDWLAYVFFKKMLDLRRE
                     LGKSKGGRH"
     gene            12403..13194
                     /locus_tag="VU534_001186"
     CDS             12403..13194
                     /locus_tag="VU534_001186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1513780.1"
                     /translation="MKIPLLTFARHKFVYVLLTLLFLALVYRDVLMTYFFFDIHAPDL
                     AKFDGQAIKNDLLKSALDFRILQFNLGFYQSFIIPIIIVLLGFQYIELKNKVLRLSIG
                     REVSYQGLKRKLTLQVASIPCLIYLVTVLIIAIITYFFGTFSPLGWNSLFSDGSGLQR
                     LLDGEIKSYLFFTCVLLIGIFINAIYFLQIVDYVGNVTRSAITYLMFLWLGSMLLYSA
                     LPYYMVPMTSLMQASYGDVSLMKLFTPYILYIVPYMVLEKYEDNV"
     gene            13187..13828
                     /locus_tag="VU534_001187"
     CDS             13187..13828
                     /locus_tag="VU534_001187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000475766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1513781.1"
                     /translation="MFKNFNNILLNRKIVLLLRIVLMMILINHLLSTAVQKQDAVIFF
                     KRELISIFSYNDYSEANLEIPKLLLNLSLFMVGWLSVILLESDLADHYHHLIRYQSSS
                     FFDYTRKRLVVISKFFTQDLFVWFLGLLPLGIHFKTVALFFLLAQLMMLYLLLSYLIA
                     LISAGAGFSFFLYFLAFVGQEWMMDHIVTVYLVLLSLLVMLIVSRLEEKFKKG"
     gene            13832..14464
                     /locus_tag="VU534_001188"
     CDS             13832..14464
                     /locus_tag="VU534_001188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001235275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEU1513782.1"
                     /translation="MRLEIINGQKIYGKRPILNQLNLVFQSGKIYGLKGDNGSGKTVL
                     LKILAGYIKLDKGKVLQDGKVYGVKNHYIQDAGILIEKVEFLSHLSLRENLELLRYFS
                     SKVTEKRIAYWIQYYDLQEFEDIEYRHLSLGTKQKMALIQAFISSPSILFLDEPMNAL
                     DEKSVRLTKQVILSYLKKENGLVILTSHISEDISDLCTDVLVVENGHIQM"
     gene            14492..14779
                     /locus_tag="VU534_001189"
     CDS             14492..14779
                     /locus_tag="VU534_001189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000940707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1513783.1"
                     /translation="MAHLKSFITRYSKVYIGLVLLIWLSFFFIPWDKPLLGIRIDIFI
                     IQKILLAFGILSILMALLSKKVSLFVFGLICCLSLWINLFITFAILPIFGN"
     gene            14925..17438
                     /gene="secA"
                     /locus_tag="VU534_001190"
     CDS             14925..17438
                     /gene="secA"
                     /locus_tag="VU534_001190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HEU1513784.1"
                     /translation="MANILKTIIENDKGEIRRLEKMADKVFKYEDQMAALTDDQLKAK
                     TVEFKERYQNGESLDSLLYEAFAVVREGAKRVLGLFPYKVQVMGGIVLHHGDVPEMRT
                     GEGKTLTATMPVYLNALSGKGVHVVTVNEYLSERDATEMGELYSWLGLSVGINLATKS
                     PMEKKEAYECDITYSTNSEIGFDYLRDNMVVRAENMVQRPLNYALVDEVDSILIDEAR
                     TPLIVSGANAVETSQLYHMADHYVKSLNKDDYIIDVQSKTIGLSDSGIDRAESYFKLE
                     NLYDIENVALTHFIDNALRANYIMLLDIDYVVSEEQEILIVDQFTGRTMEGRRYSDGL
                     HQAIEAKEGVPIQDETKTSASITYQNLFRMYKKLSGMTGTGKTEEEEFREIYNIRVIP
                     IPTNRPVQRIDHSDLLYASIESKFKAVVEDVKARYQKGQPVLVGTVAVETSDYISKKL
                     VAAGVPHEVLNAKNHYREAQIIMNAGQRGAVTIATNMAGRGTDIKLGEGVRELGGLCV
                     IGTERHESRRIDNQLRGRSGRQGDPGESQFYLSLEDDLMKRFGSERLKGIFERLNMSE
                     EAIESRMLTRQVEAAQKRVEGNNYDTRKQVLQYDDVMREQREIIYAQRYDVITADRDL
                     APEIQSMIKRTIERVVDGHARAKQDEKLEAILNFAKYNLLPEDSITMEDLSGLSDKAI
                     KEELFQRSLKVYDSQVSKLRDEEAVKEFQKVLILRVVDNKWTDHIDALDQLRNAVGLR
                     GYAQNNPVVEYQAEGFRMFNDMIGSIEFDVTRLMMKAQIHEQERPQAERHISTTATRN
                     IAAHQASMPEDLDLSQIGRNELCPCGSGKKFKNCHGKRQ"
     gene            17519..18550
                     /locus_tag="VU534_001191"
     CDS             17519..18550
                     /locus_tag="VU534_001191"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000232189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HEU1513785.1"
                     /translation="MVFTAKSSKINIEEVRALSKLEGQALERKSQRDQELEAIIRGED
                     QRILLVIGPCSSDNEEAVLEYAKRLAVLQEEVADRIFMVMRVYTAKPRTNGDGYKGLI
                     HQPNATEAPSLINGIKAVRHLHYRVITETGMTTADEMLYPENLPLVDDLISYMAVGAR
                     SVEDQQHRFVASGAGFSTGFKNPTSGNLNVMFNGIYAAQNKQSFLFLGKEVETTGNPL
                     SHAILRGALNEYGKNIPNYYYDNLIDTIAQYEKMGLENPFIIIDTNHDNSGKQYIEQI
                     RIVRQTLINRAWNEKIKQFVRGFMIESYLEDGRQNEPEVFGKSITDPCLGWDNTEALV
                     REIYKTLGE"
     gene            18552..19583
                     /locus_tag="VU534_001192"
     CDS             18552..19583
                     /locus_tag="VU534_001192"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HEU1513786.1"
                     /translation="MAFIEKGQEIDMEVIKAETQLSAEALRLKESRDRELADIISGED
                     DRILLVIGPCSSDNEEAVLEYARRLSALQKKVADKIFMVMRVYTAKPRTNGDGYKGLV
                     HQPDTSKAPSLINGLQAVRQLHYRVITETGLTTADEMLYPSNLILVDDLVSYHAVGAR
                     SVEDQEHRFVASGIDAPVGMKNPTSGNLGVMFNAIYAAQNKQTFLYHGQEVETSGNPL
                     AHVILRGAVNEYGNYMPNYYYENLLQAIERYETMGLENPFILIDTNHDNSGKQYMEQI
                     RIVRQTLQNRDWNEKIKKTVRGFMIESYLADGRQNQPEIFGCSITDPCLGWENTEALV
                     EEIYVTLTK"
     gene            19622..19990
                     /locus_tag="VU534_001193"
     CDS             19622..19990
                     /locus_tag="VU534_001193"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000061844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HEU1513787.1"
                     /translation="MRMIVGHGIDIEELASIESAVTRHEGFAKRVLTAQEMERFTSLK
                     GRRQIEYLAGRWSAKEAFSKAMGTGISKLGFQDLEVLNNERGAPYFSQAPFSGKIWLS
                     ISHTDQFVTASVILEENHES"
     gene            19980..21083
                     /locus_tag="VU534_001194"
     CDS             19980..21083
                     /locus_tag="VU534_001194"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000648075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HEU1513788.1"
                     /translation="MKASPHRPTKALIHLGAIRQNIQQMGAHIPQGTLKLAVVKANAY
                     GHGAVAVAKAIQDDVDGFCVSNIDEAIELRQAGLSKPILILGVSEIEAVALAKEYDFT
                     LTVAGLEWIQALLDKEVDLTGLTVHLKIDSGMGRIGFREASEVEQAQDLLQQHGVCVE
                     GIFTHFATADEESDDYFNAQLERFKTILASMKEVPELVHASNSATTLWHVETIFNAVR
                     MGDAMYGLNPSGAVLDLPYDLIPALTLESALVHVKTVPAGACMGYGATYQADSEQVIA
                     TVPIGYADGWTRDMQNFSVLVDGQACPIVGRVSMDQITIRLPKLYPLGTKVTLIGSNG
                     DKEITATQVATYRVTINYEVVCLLSDRIPREYY"
     gene            21102..23117
                     /gene="recG"
                     /locus_tag="VU534_001195"
     CDS             21102..23117
                     /gene="recG"
                     /locus_tag="VU534_001195"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001048793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HEU1513789.1"
                     /translation="MNLHQPLHVLPGVGPKSAEKYAKLGIENLQDLLLYFPFRYEDFK
                     TKQVLELEDGEKAVLSGQVVTPASVQYYGFKRNRLRFSLKQGEVVFAVNFFNQPYLAD
                     KIELGATLAVFGKWDRAKASLTGMKVLAQVEDDLQPVYRLAQGISQASLVKVIKTAFD
                     QGLDLLIEENLPQSLLDKYKLMSRCQAVRAMHFPKYLAEYKQALRRIKFEELFYFQMQ
                     LQMLKSENRVQGSGLVLNWSQEKVTAVKVSLPFALTQAQEKSLQEILTDMKSDHHMNR
                     LLQGDVGSGKTVVAGLAMFAAVTAGYQAALMVPTEILAEQHFESLQNLFPNLKLALLT
                     GSLKAAEKREVLETIAKGEADLIIGTHALIQDGVEYARLGLIIIDEQHRFGVGQRRIL
                     REKGDNPDVLMMTATPIPRTLAITAFGDMDVSIIDQMPAGRKPIVTRWIKHEQLPQVL
                     TWLEGEIQKGSQVYVISPLIEESEALDLKNAIALSEELTTHFAGKAEVALLHGRMKSD
                     EKDQIMQDFKERKTDILVSTTVIEVGVNVPNATVMIIMDADRFGLSQLHQLRGRVGRG
                     DKQSYAVLVANPKTDSGKDRMRIMTETTNGFVLAEEDLKMRGSGEIFGTRQSGLPEFQ
                     VADIIEDFPILEEARKVASYISSIEAWQEDPEWRMIALHLEKKEHLD"
     gene            23145..23294
                     /locus_tag="VU534_001196"
     CDS             23145..23294
                     /locus_tag="VU534_001196"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1513790.1"
                     /translation="MKIKEQTRKLTAGCSKHCFEVVDETDEVSSKHRFEVADRTDEVS
                     NIYIR"
     gene            23632..24612
                     /locus_tag="VU534_001197"
     CDS             23632..24612
                     /locus_tag="VU534_001197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetylxylan esterase"
                     /protein_id="HEU1513791.1"
                     /translation="MKNPALLEEIKTYRGRDEVPEDFDDFWDGEVKNVSTLPSYHLEE
                     RDFHIPQVKCYELTFEGSKEGKVYARIVLPKSEEKVPLIFHFHGYMGRGWDWADMLGF
                     TVAGYGVVSMDVRGQSGYSQDGLRSPLGNTVKGHIIRGAVEGRDHLFYKDVYLDIYQL
                     VEIVASLSQVDEKRLSSYGASQGGALALVAAALNPRIQKTVAIYPFLSDFRRVIEIGN
                     TSEAYDELFRYFKFHDPFHETEEEIMATLAYIDVKNLAHRIQGEVKMITGLDDDVCYP
                     ITQFAIYNRLTCDKTYRIMPEYAHEAMNVFVNDQVYNWLCGSEIPFKYLK"
     gene            25373..25600
                     /locus_tag="VU534_001198"
     CDS             25373..25600
                     /locus_tag="VU534_001198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000576349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1513792.1"
                     /translation="MIFKAFKTKKQRKRQVELLLTVFFDSFLIDLFLHLFGIVPFKLD
                     KILIVSLIIFPIISTSIYAYEKLFEKVFDKD"
     gene            25888..28785
                     /gene="nanA"
                     /locus_tag="VU534_001199"
     CDS             25888..28785
                     /gene="nanA"
                     /locus_tag="VU534_001199"
                     /EC_number="3.2.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014632427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored neuraminidase NanA"
                     /protein_id="HEU1513793.1"
                     /translation="MNRSVQERKCRYSIRKLSVGAVSMIVGAVVFGTSPVLAQEGASE
                     QPLANETQLSGESSTLTDTEKSQPSSETELSGNKQEQERKDKQEEKIPRDYYARDLEN
                     VETVIEKEDVETNASNGQRVDLSSELDKLKKLENATVHMEFKPDAKAPAFYNLFSVSS
                     ATKKDEYFTMAVYNNTATLEGRGSDGKQFYNNYNDAPLKVKPGQWNSVTFTVEKPTAE
                     LPKGRVRLYVNGVLSRTSLRSGNFIKDMPDVTHVQIGATKRANNTVWGSNLQIRNLTV
                     YNRALTPEEVQKRSQLFKRSDLEKKLPEGAALTEKTDIFESGRNGNPNKDGIKSYRIP
                     ALLKTDKGTLIAGADERRLHSSDWGDIGMVIRRSEDNGKTWGDRVTITNLRDNPKASD
                     PSIGSPVNIDMVLVQDPETKRIFSIYDMFPEGKGIFGMSSQKEEAYKKIDGKTYQILY
                     REGEKGAYTIRENGTVYTPDGKATDYRVVVDPVKPAYSDKGDLYKGDQLLGNIYFTTN
                     KTSPFRIAKDSYLWMSYSDDDGKTWSAPQDITPMVKADWMKFLGVGPGTGIVLRNGPH
                     KGRILIPVYTTNNVSHLDGSQSSRVIYSDDHGKTWHAGEAVNDNRQVDGQKIHSSTMN
                     NRRAQNTESTVVQLNNGDVKLFMRGLTGDLQVATSKDGGVTWEKDIKRYPQVKDVYVQ
                     MSAIHTMHEGKEYIILSNAGGPKRENGMVHLARVEENGELTWLKHNPIQKGEFAYNSL
                     QELGNGEYGILYEHTEKGQNAYTLSFRKFNWEFLSKNLISPTEAKVKRTREMGKGEMG
                     KGVIGLEFDSEVLVNKAPTLQLANGKTATFLTQYDSKTLLFAVDKEDIGQEIIGIAKG
                     SIESMHNLPVNLAGARVPGGVNGSKAAVHEVPEFTGGVNGTEPAVHEIAEYKGSDSLV
                     TLTTKKDYTYKAPLAQQALPETGNKESDLLASLGLTAFFLGLFTLGKKREQ"
BASE COUNT         8756 a         5265 c         6422 g         8372 t
ORIGIN      
        1 aaagcacaaa atccgcttgg gaaaccaaac ggattttgtg gttgaaaaca atatttttga
       61 gcctttcctt aagtgattac ggacggtagc gactttcttc aaaattccat acctaaactt
      121 tgagacacta ggctcaaagt ttccgaatac ctgaaaccat tagatttcag gtgtttctat
      181 cacggcggaa aggctaggta agtcctcgcc tcactatcga aaaatatgca tgatttccat
      241 accaaagtat atttagtatc aagctatagt taatctacgc tttaaaaatc cacttgggaa
      301 accaaacgga ttttttacgt gtcaaagcat ttgccagaaa aagtcaataa tataggtcag
      361 accgtaggta taaaccacga gggtaaaggg tttggtcaga atgatgatgg tcatgtagcg
      421 cttgaagctc atcttggtca gggcagccag catacagaga aagtcagctg ggctaatggg
      481 ccaaatcatc ataaaaataa agaagcggtc aaaacgattg cccttatcta gccagccgat
      541 gtacttgttg taggtgcgct tgctgacgac agactggaca aaggcagctc cgtataggcg
      601 cactagataa aagataatgg cacagccaat cacgatgccg atatagttgt agatagtccc
      661 gatgatgtgc ccgtagataa agaccccagc caccgaggtc aaggcccctg gaatgatagg
      721 gacgacagtc tgtaaaatct gtaaaaagat aaagagaggt ggaccccaga tgcctgcctg
      781 ctggataaag gcagagaggg tttccttgga ttgtaaaatc ccagcctgat aagcccaaat
      841 acagaaaatc aaactcccaa ccccaccgac aatcgatgag atattgataa ctcgctgcag
      901 aaggggagaa acagctttca tttgtttatc ctgtgacatg taaactcctc atagatagta
      961 tatttctact ataccatatt ttggaggaga aagggggaat gagtcttttt tgataaggaa
     1021 tagaaagtaa atagcccttc gagacttaga ataggtctgt caactaaagg ttatatgcat
     1081 tctaggtttc gaataatcgc aattccataa atttaaaagc attctaagtt tcgaatagct
     1141 tatctgagat aattttgagg cattcgcgct ttcgaatagt cattttccct aaagtttaga
     1201 tgtattctga agctagaaag actaaaatct aaaagtagta agagtctctc tctgatggac
     1261 gtaatttatg gctagtatga atcctttgaa ttgttagtta attttaatat taatcagttc
     1321 tgaaataatt actaaatata gttagatagt gaattaatta ttgctaaatt tcaagttcaa
     1381 gttagtcatc cagaagtctt ctctggggga cttgtagttc aagcattttt taggatagtt
     1441 gttaatctac ttttcgatga atgcgacttc cttggtagtc gttttcttag ttcccttagg
     1501 cttaggtaac catctatgaa tgagcctgtt gtgattttca ttagatccta taggggtgtg
     1561 cataatagat atagcagatt gaaactagaa tagtatacat ctacttctaa aacattgtta
     1621 gaaatcaatt tgactgtcct gatcaatttg tcctgttctt atttcatttt actatataat
     1681 ccttagaaaa catatcggac aagcggttga attctgttcc gtccattagt agataaagga
     1741 ttactccttc ttgaaatgac agatgaactt gtttcttata aaaatgttgt ctgaaactat
     1801 tagccttttt ccagaagttt tagaggaaga aaactttacg aggaaaaagg agttactcaa
     1861 ataacaattc aggattaaaa atagacagtt gaggagcgga aggtataaat taagtttgct
     1921 gctgtataat ggatttatca ctaatactct tcgaaaatct cttcaaacca cgtcagcttc
     1981 gccttgccgt agatatagtt actgacttcg tcagttctat ccacaacctc aaaacagtgt
     2041 tttgagctga cttcgtcagt tttatctgca acctcaaagc tgtactttga gcagtctacg
     2101 gctagcttcc tagtttgctc tttgattttc attgagtata aaagtgctcc aggccatatt
     2161 ttacacagca atagtcttct aaaaatggac aaaaaacatt gtaaaggcta tcaaaaagga
     2221 gtataatgag tgcaagaaat ttcggaggtg aaagatgcta gaagtaagaa gtctagagaa
     2281 aagttttgga tccaagcaag ttttgtttgg tattgacttt caagcgcgac caggtcgtat
     2341 tttgggacta gtcggaaaaa atggtgctgg aaaaacaacg attttccata gtattttgaa
     2401 attcctagaa tatcagggag aaatcggtct ggatggtcag gatattcgtc aggagaccta
     2461 tgctcggatt ggttatctgc ctgaagaacg cagtctcatg cctaaattga cagttcttga
     2521 acaagttcgc tacttggcga ctctaaaagg catggatgcc aaagaagtca aagaaaaact
     2581 ccctcaatgg atgaagaggt tggaagtgaa aggaaagctg acagataaaa tcaagagtct
     2641 gtcaaaagga aatcagcaga agattcagct cattattact ctgattcatg aaccagacct
     2701 gattatcttg gatgagcctt ttagtggatt ggacccagtt aatacagaat tgctcaaaca
     2761 agtcattttt caggaaaaag agcgcggagc aaccattatc ttttctgacc atgtcatgac
     2821 caatgttgag gaactttgtg acgatattct gatgatccga gatggccgtg tggtcttgca
     2881 cggaccagtt caggatgtcc gcaatcaata cgggaaaacg cgtctctttg tttcaagtga
     2941 acgaagcaag gaagaattgg aaaatcttcc tcatgtcaaa caggtgagct tgaccaaaca
     3001 aggcagttgg aaattgattt tggaggatga gagcgctgga agggaactct tctcaatctt
     3061 gactcaaggt caatatatcg caacatttga ccaacaagcg ccaactatcg atgaaatctt
     3121 taaactagaa tcaggagtgg aagtatgaga aatatgtggg ttgtaatcaa ggaaacctat
     3181 cttcgacatg tcgagtcatg gagtttcttc tttatggtga tttcgccgtt cctcttttta
     3241 ggaatctctg taggaattgg gcatctccaa ggttcttcta tggctaaaaa taataaagtg
     3301 gcagtagtga caacagtgcc atctgtagca gaaggactga agaatgtaaa tggtgttaac
     3361 ttcgactata aagacgaagc aagtgccaaa gaagcaatta aagaagaaaa attaaaaggt
     3421 tatttgacca ttgatcaaga agatagtgtt ctaaaggcag tttatcatgg cgaaacatcg
     3481 cttgaaaatg gaattaaatt tgaggttaca ggtacactca atgaactgca aaatcagctt
     3541 aatcgttcaa ctgcttcctt gtctcaagag caggaaaaac gcttagcgca gacaattcaa
     3601 ttcacagaaa agattgatga agccaaggaa aataaaaagt ttattcaaac aattgcagca
     3661 ggtgccttag gattctttct ttatatgatt ctgattacct atgcgggtgt aacagctcag
     3721 gaagttgcca gtgaaaaagg caccaaaatt atggaagtcg ttttttctag cataagggca
     3781 agtcactatt tctatgcgcg gatgatggct ctgtttctag tgattttaac gcatattggg
     3841 atctatgttg taggtggtct ggctgccgtt ttgctcttta aagatttgcc attcttggct
     3901 cagtctggta ttttggatca cttgggagat gctatctcac tgaatacctt gctctttatt
     3961 ttgatcagtc ttttcatgta cgtagtcttg gcagccttcc taggatctat ggtttctcgt
     4021 cctgaggact cagggaaagc cttgtcgcct ttgatgattt tgattatggg tggttttttt
     4081 ggagtgacag ctctaggtgc agctggtgac aatctcctct tgaagattgg ttcttatatt
     4141 ccctttattt cgaccttctt tatgccgttt cgaacgatta atgactatgc ggggggagca
     4201 gaagcatgga tttcacttgc tattacagtg atttttgcgg tggtagcaac aggatttatc
     4261 ggacgcatgt atgctagtct cgttcttcaa acggatgatt tagggatttg gaaaaccttt
     4321 aaacgtgcct tatcttataa atagaagagc cttgcgaaag cgaggttttt aaaggtgaaa
     4381 agggtggaat cacgaaccta attatgtaca cattatgtaa acaggttgct tgaaaactca
     4441 attgtatagt gaactgaatc tggaatagga taatattact tctaaaacat tcttataaat
     4501 tgatttgaat tccaaaatcc catcgttccg ttcttatttc attttgcgat atagtgaaag
     4561 gaaataagtc agctcacaaa aaacgcatat taccaaggtt cttatgaact gcccccaaaa
     4621 gttagacaga aaaaatctaa cttttggggg gcagtacata ttcaacacct gatactatgc
     4681 gttttctaat tttaaagact ttttgcctgg tctcttttgt tctatgagta tgttacatat
     4741 ctaggtaaaa attatttaaa gcaaattaac cttatttctc aagatgtagt aggttccgag
     4801 ataaaagata gctatgaata tgagttcttc aacaatggct atacctgctc ccatatagaa
     4861 atggtcattg agtcctacca gtgaattgac atagaaatta gaactaagat tgaagaaaag
     4921 ttcaataaat ccaatgacga tttggatacc aatgtagact gcaacagcga gtgctgtacg
     4981 gtattcattg aaaagctgtc caatggaaat agccaggtag atgcagagga ttcctgaaat
     5041 agtatttagt aggaaggata tacctgtaag aaagatctga gggagatgtg tttctacaaa
     5101 tgtaatcaca taagaaagag gaatccattc tggagctgtt aaagccagaa taataacagc
     5161 acttagagcc aatacagcgg tgctaatcaa tgaccagata aaggcaccga ttagtttggc
     5221 tgtgatgata tggtgttcag aaactggcaa ggtcaaagtc agatagcctt gtcggtcgta
     5281 gacactacct ttgaagcgtt taataatcaa gaaaatggtt gaaatcccaa gtgtaagcat
     5341 caagccacca aagactgtag ctagaaaaag tagcatagta gcctgacttt cttggtaagg
     5401 tagattttta aagccttgtg tctgtattcc gatgagggca gaaaggacta gcacggctgc
     5461 gtagagggct aaataccact tgttaacatt tttaaattcg tagcgaacta aattccaaaa
     5521 cataaataat ctcctttgct taggccttaa attcctgacg gaagagttgg tcaatggatt
     5581 cacctgactc gtagcgaata tcatctacat ttccttgacg gacgactttt ccgtctttta
     5641 ggaagacaat ttcatccaag attggctcga tatcagaaat caagtgggta gaaatcaaaa
     5701 cggtagaagt tggtgagtag ttgttgataa tggtattgag gatataagca cgggctgctg
     5761 gatccacccc accaatgggt tcgtccaaaa catagagacg agcatcacgg ctcataacca
     5821 aaatcagttg aaccttttct ttgtttcctt ttgatagttt cttgagacga ctattttcat
     5881 caatgcccag gtctgcaagt agatgatggg cgcgttcaag attgaaatct ttatagaagg
     5941 tcttgaagta ggttagggct tctttgacct tcatttgctc attgagatag gtcgtatcag
     6001 gcaaataagc tacaacggcc ttggttgctg ggcttgggtc catgtcgttg atgaggacac
     6061 gtccttgatc tggttgtaag aggccattaa ttagtttaat cagggttgtt tttcctgagc
     6121 cgtttggccc aagaaggccg acaatttttc cagctggaat gtcaagagaa acattttcaa
     6181 gggctggtgt tgctccatat gatttggata cattttcaaa tactagtaat gacataggct
     6241 taaactcctt taatataatc actgactacg cctggtagtt cttctttttc atagccaaaa
     6301 tgggtcatgg aggaaacgaa gtgttccaat tcttcttctg ataattgttt gcgtgactgg
     6361 gcgattagct ccttatcctt agtcacaaat cgtccagttg ttcgcttgct gtagacaaat
     6421 ccttctcgtt caaggtctga taaggctctt tggatggtat tgggattgac accagcctcg
     6481 ctagctagct ccctcacggt tggaagttgt tgattgggtt ccagtgtatg ggaaacaatc
     6541 tgaagcttga ttttctccat aatctgtaaa tagatgggtt ttttgttgtc aaatgtccag
     6601 gacatcttag tctcctttct tttaccttgt tgtcttaatt aaataataca acaaaacaaa
     6661 aaacttgtca agcaaaaaga agaattgttt tgggaatcgc ttaaaaaatg gtataatgaa
     6721 aagaaaacga taaggaggga aaggatgcgt tgtccaaaat gtggggctac caagtcaagt
     6781 gttatcgata gtcgccaagc agaagaaggg aacaccattc gtagaagacg tgagtgcgac
     6841 gaatgccaac accgttttac aacctacgaa cgagtagaag aaagaacctt agtggttgtt
     6901 aaaaaagatg gcacacggga acaattctcc agagataaaa tctttaatgg gattatccgc
     6961 tcagcccaga aacgtcctgt gtcaagtgat gaaatcaaca tggtagtcaa tcgtatcgaa
     7021 cagaaactcc gtggtcgaaa tgaaaatgaa attcaaagtg aggacattgg ttcactcgtc
     7081 atggaggagt tggctgaatt ggacgagatt acctatgtac gttttgctag tgtctatcgt
     7141 agttttaagg atgtcagtga gttagagagc ttgctccaac aaatcaccca gtcctctaaa
     7201 aagaaaaagg aaagataaat gaagccaatt gaccgttttt cttatctaaa gaataatcgg
     7261 gtgtcgcaag atacctcatc tctggtacag tgctacctcc cgattatcgg tcaggaggca
     7321 ctgagccttt atctttatac aatcagtttt tgggataatg gtagaaagga atatcttttt
     7381 tcaagcattc tcaaccatct caactttggg atggatagac tgataaaatc attgaaaatc
     7441 ttatctgctt ttaatctctt gaccctctat caaaagggtg atgtttatca gctagccctc
     7501 catgctcctc tatctagtca agacttcttg gggcatcctg tttatcgcag actcttagag
     7561 aaaaagattg gcgatgtagc tgtggaggat ttgaaagttg aaagtgctga tggtgaagaa
     7621 atacctgtct cactcaatca agtctttcca gaattggcag aactaggcag tcaagaagac
     7681 cttggtctca agaagaaagt ggccaatgat tttgacttgg aacattttcg ccagctgatg
     7741 gctcgagatg gacttcgttt tgcggatgag cagtccgatg tcttaaacct ctttgctatt
     7801 gccgaggaga agaaatggac ttggtttgaa acctatcaat tggccaagtc aacagctgtt
     7861 tcccaggtta tttcaaccaa acgcatgcgt gaaaaaattg ctcaaaaacc agtttcctct
     7921 gactttagtc ttaaggaagc gaccattatc aaagaagcta aaagtaaaac tgccctgcag
     7981 ttcttagcag aaatcaagca aacacgcaag ggaaccatta cccaaacaga aagagaactc
     8041 ttgcaacaga tggctggctt gggcttactg gacgaagtca tcaatattat tctcttattg
     8101 acctttaata aggtggattc ggcaaatatc aatgagaaat atgccatgaa ggtagccaat
     8161 gactatgcct atcaaaagat tcattcggca gaagaggccg ttttacgaat tcgtgatcga
     8221 gggcagaaag caaaaacaca aaaacagaat cagactgccc cagaaaaaac caatgttcct
     8281 aaatggagta atcctgaata taagaatgaa accagcgagg aaactcgtct ggaactagaa
     8341 cgtaagaagc aagaactatt agctcgatta gaaaaaggag gagattagat ggaaagtgtc
     8401 ggagacgtac tcaaacgtca acccagccgt ttttattatc aagatttggt ccagaaaatc
     8461 atgaaggacc ctgatgttgc ggcctttatc cagcaagaat ccttaactcc aaaggaatta
     8521 aatcgcagta tctccaagtt taatcagtac atcaccgagc gtgacaagtt tctccgtggg
     8581 gatacggatt atattgccaa aggctacaag ccgattttgg ttaagaatca tggttatgca
     8641 gatgtttcat atgaagaaac tcctgagcta atcgcggctg aaaaagaagc ggctattaag
     8701 aaccgtctca agttaatcaa tctaccagcc agtctcaaga aagctagttt ggctcaagtt
     8761 gacttggatg atttggggcg cttaccagtt tttgaaaagc tactagcctt cgtggagcaa
     8821 tatccagcta ttcgaaaagg tctttactta tatggagact ttggtgtggg taaaagtttc
     8881 atggtggcgg ccttagctca tgatttatca gaaaaacgtg gtgtttcatc aactctcctc
     8941 cactatccta gctttgtcat tgatgtcaaa aatgctatca gtgatggcaa tgttaagacc
     9001 ttggtggatg agattaagct gtctgaggtc ctgattttag atgatattgg cgccgagcaa
     9061 tcaaccgttt gggtgcgtga cgaaatcctg caggtcattc tccaatatcg gatgcaggaa
     9121 aatttaccga cctttttcac atccaacttc aactttgaag atttggagaa gcattttgcg
     9181 aaagtgaaac atggaaatga cgaaacctgg gaagccagac gggtcatgga acgcatccgt
     9241 tatttggctg aggagactcg tttagaagga gtaaaccgtc gatgacagaa accattaaat
     9301 tgatgaaggc tcatacttca gtgcgcaggt ttaaagagca agaaattccc caagtagact
     9361 taaatgagat tttgacagca gcccagatgg catcatcttg gaagaatttc caatcctact
     9421 ctgtgattgt ggtacgaagt caagagaaga aagatgcctt gtatgaattg gtacctcaag
     9481 aagccattcg ccagtctgct gttttccttc tctttgtcgg agatttgaac cgagcagaaa
     9541 agggagcccg acttcatacc gacaccttcc aaccccaagg tgtggaaggt ctcttgatta
     9601 gttcggtcga tgcagctctt gctggacaaa acgccttgtt ggcagctgaa agcttgggct
     9661 atggtggtgt gattatcggt ttggttcgat acaagtctga agaagtggca gagctcttta
     9721 acctacctga ctacacctat tctgtctttg ggatggcact gggtgtgcca aatcaacatc
     9781 atgatatgaa accgagactg ccactagaga atgttgtctt tgaggaagaa taccaagaac
     9841 agtcaactga ggcaatccaa gcttatgacc gtgttcaggc tgactatgct ggggcgcgtg
     9901 cgaccacaag ctggagtcag cgcctagcag aacagtttgg tcaagctgaa ccaagctcaa
     9961 ctagaaaaaa tcttgaacag aagaaattat tgtagaaagt gagaaattat ggccctacca
    10021 actattgcca ttgtaggacg tcccaatgtt gggaaatcaa ccctatttaa tcggatcgct
    10081 ggtgagcgaa tctccattgt agaagatgtc gaaggagtga cacgtgaccg tatttatgca
    10141 acgggtgagt ggctcaatcg ttcttttagc atgattgata caggaggaat tgatgatgtc
    10201 gatgctcctt tcatggaaca aatcaagcac caggcagaaa ttgccatgga agaagcagat
    10261 gttatcgttt ttgtcgtgtc tggtaaggaa ggaattactg atgcagacga atacgtagct
    10321 cgtaagcttt ataagaccca caaaccagtt atcctcgcag tcaacaaggt ggacaaccct
    10381 gagatgagaa atgatatata tgatttctat gctctcggtt tgggtgaacc attgcctatc
    10441 tcatctgtcc atggaatcgg tacaggggat gtgctagatg cgatcgtaga aaatcttcca
    10501 aatgaatatg aggaagaaaa tccagatgtc attaagttta gcttgattgg tcgtcctaac
    10561 gttggaaaat caagcttgat caatgctatc ttgggagaag accgtgttat tgctagtcct
    10621 gttgctggaa caactcgtga tgccattgat acccacttta cagatacaga tggtcaagag
    10681 tttaccatga ttgatacggc tggtatgcgt aagtctggta aggtttatga aaatactgag
    10741 aaatactctg ttatgcgtgc catgcgtgct attgaccgtt cagatgtggt cttgatggtc
    10801 atcaatgcgg aagaaggcat tcgtgagtac gacaagcgta tcgcaggatt tgcccatgaa
    10861 gctggtaaag ggatgattat cgtggtcaac aagtgggata cgcttgaaaa agataaccac
    10921 actatgaaaa actgggaaga agatatccgt gagcagttcc aatacctgcc ttacgcaccg
    10981 attatctttg tatcagcttt aaccaagcaa cgtctccaca aacttcctga gatgattaag
    11041 caaatcagcg aaagtcaaaa tacacgtatt ccatcagctg tcttgaacga tgtcatcatg
    11101 gatgccattg ccatcaaccc aacaccgaca gacaaaggaa aacgtctcaa gattttctat
    11161 gcgacccaag tggcaaccaa accaccaacc tttgtcatct ttgtcaatga agaagaactc
    11221 atgcactttt cttacctgcg tttcttggaa aatcaaatcc gcaaggcctt tgtttttgag
    11281 ggaacaccga ttcatctcat cgcaagaaaa cgcaaataaa aaagtagaat ctggaatgac
    11341 agttccggat ttttttgata taataaaata atagaaaacg ctatcaaaag aaggggggat
    11401 gtcggtgatg gaacatttgt ttaaattctt acttttagca ccgtactttt attttgataa
    11461 ctggattgaa aaggccaaca gaaatagtaa gttttttcca attttttatt atttttactg
    11521 gttttacatc cccttctatt ctctttttag ccttgcttgg acagttgttt cagttctgtt
    11581 tttcaatacc gtcttgagaa atgtgacaga tatcaagtta tggggcattt ggtttctttt
    11641 tattctgcta gctattggta tgaattggtt aacttattcc tgtttcaaag aaatgtttcg
    11701 cttgagacag gaactaggga agtctaaggg tggaaggcat tgatttatat cggtttctat
    11761 ttgtaggagg tggcttatgg tacctctaaa atcatttatt acacgctatt ccaaggttta
    11821 tattggtaat aacatttaat agaacgaaac taaagaaaat aatttaaaag aggaggtttg
    11881 tgatggaaca cttgtttaaa atgataatct tattaccctg tttttacttt ttcagctgga
    11941 ttgacaagga taatagagaa agtaaatttt tcccaatttt ttactatttt tactggattt
    12001 acatcaccct ctatgctctt tttagccttg cttggacagt tttttcagtt ctgtttttca
    12061 atatcgtctt gagaaatttg acagatatca agttatgggg tatttggcta ttattactac
    12121 ttatcgcttt tgctagtgac tggttagcct atgtcttttt caaaaaaatg cttgacttga
    12181 gacgggaact agggaagtct aaaggcggaa ggcattgatt tatactcttc gaaaatctct
    12241 tcaaaccacg tcaacgtcgc cttggattat atatgtaact gacttcgtca gtcttatcta
    12301 caacctcaaa gcagtgcttt gagcaacttg cggctagttt cctagtttgc tctttgattt
    12361 tcattgagta ttatattact ttctatttgt aggaggtggc ttatgaagat tcctctctta
    12421 acttttgcaa ggcataaatt tgtttatgtc ttgcttactt tgctttttct tgctttggtt
    12481 tatcgtgatg ttttgatgac ttatttcttt tttgatattc atgcgcccga tctagctaaa
    12541 ttcgatggac aagcaattaa aaatgactta ttaaaatcag cattagattt tcgtattctc
    12601 cagttcaatc taggttttta tcaatcattt attattccaa tcatcattgt tttgctaggt
    12661 tttcaatata ttgagctgaa aaataaagtt ttacgattga gtattggaag agaagtgagt
    12721 tatcaagggt taaaaagaaa gttgactttg caagttgcaa gtatcccttg tttgatatat
    12781 ttagtgactg tgctgataat tgcaattata acctatttct ttgggacttt ttctcctctt
    12841 ggatggaatt ctctattttc tgatggaagt ggtttacaaa gactcctaga tggagagata
    12901 aaaagctatt tgttctttac ttgtgtccta ctaatcggta ttttcatcaa tgcaatctat
    12961 tttttacaaa tagttgatta tgtggggaat gtgactcgtt cggcaatcac ctatttgatg
    13021 tttctttggc ttggttctat gctgctttat agtgccttgc cttactatat ggttcctatg
    13081 acgagtttga tgcaagctag ctatggggat gtaagtttga tgaaactctt tactccttat
    13141 atcctttata ttgtccctta catggtgctt gaaaaatatg aagataatgt ttaagaattt
    13201 taacaatatt ttgctaaata gaaagattgt tttactactt cgtatagttc tgatgatgat
    13261 tttgataaac catctattgt caacagcggt tcaaaagcag gatgctgtta tctttttcaa
    13321 gagagaattg atttcaattt tttcctataa tgactattct gaagcgaatt tagaaatccc
    13381 caaactattg ttaaaccttt cgcttttcat ggtaggatgg ctctctgtca ttttacttga
    13441 aagtgatttg gcagaccatt accatcactt gattcgctat caatcaagct cctttttcga
    13501 ttatacaagg aaacgattgg ttgtcatttc taaatttttt actcaagatt tgtttgtctg
    13561 gtttcttggt ttacttcctc taggaattca tttcaaaaca gtcgcacttt tctttttact
    13621 tgctcagtta atgatgttgt acttactact gtcttatctg atagcactga ttagtgcggg
    13681 cgctggtttt tccttttttc tctatttttt agcatttgtg ggacaagaat ggatgatgga
    13741 tcatattgta acagtgtatt tagtactctt aagtttatta gttatgttga ttgttagtcg
    13801 cttggaagag aaatttaaga aaggataaac gatgagactt gaaattataa atggacagaa
    13861 aatttatggg aaaagaccta ttttaaatca gttgaatttg gtgtttcaat caggaaaaat
    13921 ttatggactt aaaggtgata atggatctgg caagacggtt cttttaaaga tacttgctgg
    13981 ttatattaag cttgacaaag gaaaagttct tcaagatggt aaagtttacg gggtaaaaaa
    14041 tcattatatt caggatgcag gaattttaat tgaaaaagtc gagtttttat ctcatttatc
    14101 cctgagagaa aatttggaac tgttaaggta tttttcatct aaagttacgg aaaaaagaat
    14161 tgcctattgg attcaatact atgatttaca ggaatttgaa gacattgaat accgtcattt
    14221 atccttagga acaaagcaaa aaatggcctt gattcaagcc tttatttcct ctccttctat
    14281 actctttctc gatgaaccta tgaatgcttt ggatgagaag agtgtgaggt taaccaaaca
    14341 ggtcatttta tcttacctga aaaaagaaaa tggtctggtt atcctgacgt cgcacatatc
    14401 ggaagatatt tcagaccttt gtacagatgt attagttgtc gaaaatggac atatacaaat
    14461 gtaaaggata tacaatccta ggagatggct tatggcacat ctaaaatcat ttattacacg
    14521 atattccaag gtttatattg gtttagttct gctgatctgg ctgtctttct tctttatccc
    14581 ttgggataaa ccacttctgg ggataaggat tgacatcttc atcatacaga aaatcttgct
    14641 agcttttgga attctgtcca ttctcatggc cttgctgtcc aagaaagtca gtctctttgt
    14701 ttttggactg atttgctgtc tttctctttg gattaactta tttatcacat ttgccatttt
    14761 gccgattttt ggcaattaaa cagtcataaa agtcggagag gttagcttga aaactaacct
    14821 ctttttcctt ttcaaaatgg ggattcttcc ttgaaaataa tcagtaattg tgctaaaatt
    14881 aaaggaacat tctaaaatat tcggaattta aagtaaggaa aaacatggct aatattttaa
    14941 aaacaattat cgaaaatgat aaaggagaaa tccgtcgtct ggaaaagatg gctgacaagg
    15001 ttttcaaata cgaagaccaa atggctgctt tgactgacga ccaactaaaa gcaaaaacag
    15061 ttgaatttaa ggaacgttat caaaatggag aatcactgga ttcattgctt tacgaagcat
    15121 ttgcggttgt ccgtgaaggt gccaaacgtg tcctaggtct cttcccttat aaggttcagg
    15181 tcatgggggg gattgttctt caccatggtg acgtgccaga gatgcgtaca ggggaaggga
    15241 aaaccttgac tgcgaccatg ccggtatacc tcaatgccct ttcaggtaaa ggggttcacg
    15301 tagttacggt taatgaatac ctgtcagaac gtgacgcgac tgagatgggt gaattgtact
    15361 cttggcttgg tttgtcagta gggattaact tggctaccaa atctccaatg gagaaaaaag
    15421 aagcctatga gtgtgatatt acttactcaa ctaactcaga aatcggattt gactaccttc
    15481 gtgacaacat ggtcgttcgc gccgaaaaca tggtacaacg tccgcttaac tatgccttgg
    15541 tcgatgaggt tgactctatc ttgattgacg aggctcgtac acctttgatt gtatcaggtg
    15601 ccaatgcggt tgaaaccagt cagttgtatc acatggcaga ccactatgta aaatctttga
    15661 acaaagatga ctacatcatc gatgtgcagt ctaagactat tggtttgtct gattcaggga
    15721 ttgacagggc tgaaagctac ttcaaacttg aaaacctcta tgacatcgaa aacgtggctt
    15781 tgactcactt tatcgataac gcccttcgtg ccaactacat catgcttctc gatattgact
    15841 atgtggtgag cgaagagcaa gaaatcttga ttgtcgacca atttacaggt cgtaccatgg
    15901 aaggtcgtcg ttattctgat ggattgcacc aagctattga agccaaagaa ggtgtgccaa
    15961 tccaggatga aaccaagaca tctgcctcaa tcacgtacca aaacctcttc cgtatgtaca
    16021 agaaattgtc tggtatgacg ggtacaggta agactgagga agaagaattc cgtgaaatct
    16081 acaacattcg tgttattcca atcccaacaa accgtcctgt tcaacgtatt gaccactcag
    16141 accttcttta tgcaagtatc gaatctaagt ttaaagcggt tgtcgaagac gttaaggctc
    16201 gttaccaaaa gggtcaacct gtcttggttg gtacagtagc ggttgaaact agtgactaca
    16261 tttctaagaa attggttgca gctggtgttc ctcacgaagt cttgaatgcc aaaaaccact
    16321 atagagaagc ccaaatcatc atgaatgctg gtcaacgtgg tgccgttacc atcgcaacca
    16381 acatggcggg tcgtggtacc gacatcaagc ttggtgaagg tgttcgtgaa cttggaggac
    16441 tttgtgttat tggtacagaa cgtcatgaaa gtcgtcgtat cgataaccag cttcgtggac
    16501 gttcaggtcg tcaaggagat ccaggtgagt cacaattcta cctatctctt gaagatgatt
    16561 tgatgaaacg ttttggttct gaacgcttga agggaatctt tgaacgcttg aacatgtctg
    16621 aagaggccat tgagtctcgc atgttgacgc gtcaggttga agcagctcag aaacgtgtcg
    16681 aaggaaataa ctacgatacc cgtaaacaag tccttcaata cgatgatgtc atgcgtgaac
    16741 aacgtgagat tatctatgct caacgttacg atgtcatcac tgcagatcgt gacttggcac
    16801 ctgaaattca gtctatgatc aaacgcacga ttgaacgtgt cgttgatggt catgcgcgtg
    16861 ccaaacaaga tgaaaaacta gaggcaattt tgaactttgc taagtacaac ttgcttcctg
    16921 aagattctat tacgatggaa gacttgtcag gcttgtctga taaggccatc aaggaagagc
    16981 ttttccaacg ttccttgaag gtttacgata gtcaggtttc aaaactacgc gatgaagaag
    17041 cagttaaaga attccaaaaa gttttgattc tacgagtggt ggataacaag tggacagatc
    17101 atatcgatgc ccttgatcaa ttgcgtaacg cggttggact tcgtggctat gctcagaaca
    17161 accctgttgt tgagtatcag gcagaaggtt tccgtatgtt taatgatatg attggttcga
    17221 ttgagtttga tgtgacacgc ttgatgatga aagcacaaat tcatgaacaa gaaagaccac
    17281 aggcagaacg tcatatcagt acaacagcga ctcgcaatat cgctgctcac caagcaagta
    17341 tgccagaaga tttggatttg agccagattg gacgcaatga actttgccca tgtggttctg
    17401 gtaagaaatt taaaaactgt cacggtaaaa gacaataaaa tgagatagtt tagaggcgga
    17461 tatcttgtga aaagtaaatt tttactgggt atccgtttgc tttataagga gatgagttat
    17521 ggtatttaca gcaaaaagct ctaaaataaa tatagaagaa gttcgtgcct tgtcaaaatt
    17581 agaaggtcag gctttggaga ggaaatcaca gcgagatcaa gagctagaag ccattatacg
    17641 tggagaagac cagcgaattc tcttggtaat cgggccatgc tcatctgaca acgaagaagc
    17701 tgtccttgaa tacgctaagc gtttggcagt cctacaagaa gaagtggcag atcgtatctt
    17761 tatggttatg cgtgtttata ctgccaaacc ccgtaccaac ggagatggct ataagggctt
    17821 gattcaccag cctaacgcga cagaagcgcc tagtcttatc aatggaatca aagccgttcg
    17881 ccatcttcac tatcgtgtca tcacagaaac agggatgaca actgctgatg aaatgcttta
    17941 tcctgaaaac cttccgcttg tagatgattt gatttcttac atggcagttg gtgcccgttc
    18001 agttgaagac cagcaacacc gctttgtggc aagtggggca ggattttcta ctggttttaa
    18061 aaatccaacc tctggaaatc tcaatgtcat gtttaatggg atttatgctg ctcaaaacaa
    18121 acaaagtttc cttttcttag gaaaagaagt agaaacaact gggaacccgc tttcacacgc
    18181 tattcttcgt ggtgctctta atgagtatgg aaaaaatatt cccaactact attatgacaa
    18241 tttaattgat accattgccc agtatgagaa aatgggcttg gaaaatcctt ttatcatcat
    18301 tgataccaat catgacaatt ctggtaagca gtatattgaa cagatccgaa ttgtccgcca
    18361 gaccttgatt aaccgtgctt ggaatgaaaa aattaagcag ttcgttcgtg gttttatgat
    18421 tgagtcttat ctggaagatg gtcgacaaaa tgagccagaa gtatttggta agtctatcac
    18481 agacccttgc ctgggttggg ataacacaga agctcttgtc agagaaattt acaaaacgtt
    18541 aggagaataa gatggcattt attgaaaaag gtcaagaaat cgatatggaa gtcatcaagg
    18601 ctgaaaccca attgtctgcg gaagccttga gactcaagga aagccgtgac agggaattgg
    18661 cagatattat ttcaggggaa gatgaccgta ttctcttggt gattggtcct tgctcttctg
    18721 ataatgaaga ggcggtcttg gaatatgctc gccgtttatc tgccttgcaa aagaaggtag
    18781 cggataagat tttcatggtc atgcgcgtgt atactgctaa gcctcgtacc aatggagacg
    18841 gctataaagg attagttcac cagccagata cttctaaggc tccaagcctg attaatggct
    18901 tgcaggctgt gcgccagttg cactaccgcg tgattacaga gactggtttg acaacggcag
    18961 atgagatgct ttatccgtca aatctgatct tggtggatga cttggtcagc taccatgccg
    19021 ttggagctcg ttctgtggaa gaccaagagc accgctttgt ggcttctggg attgatgcac
    19081 cagtagggat gaaaaatcca acctcaggaa atttgggtgt tatgtttaac gccatctatg
    19141 ctgctcaaaa caagcaaacc ttcctttatc atgggcagga agttgagaca tcaggtaatc
    19201 ctttggccca tgttatcctc cgtggagcag tcaacgagta tggcaattat atgccgaatt
    19261 actactatga aaatctactc caagccattg aacgctatga aaccatggga cttgaaaatc
    19321 cttttatcct cattgacacc aaccatgata actcaggcaa gcaatatatg gagcagattc
    19381 gaattgttcg ccagaccttg cagaatcgtg attggaatga gaaaattaaa aagacggttc
    19441 gaggatttat gattgaatct tacctagcag atggtcgtca aaaccaacca gagatctttg
    19501 gttgctctat tactgaccct tgcctaggtt gggaaaatac agaggccttg gtagaagaga
    19561 tttatgttac cttgacaaaa taagtgaaaa ggatggagtt ggggaatctc aactcctttt
    19621 gatgagaatg atagttggac acggaattga catcgaagaa ttggcttcga tagaaagcgc
    19681 agttacacga catgaaggat ttgctaagcg tgtactgacc gctcaggaaa tggagcgctt
    19741 caccagtctc aaaggacgca ggcaaataga atatttagct ggtcgctggt cggctaagga
    19801 ggccttttcc aaggctatgg gaacgggcat tagcaagctc ggttttcagg atttggaagt
    19861 cttgaacaat gaacgtgggg cgccttattt tagtcaggca ccattttcag gaaagatttg
    19921 gctgtctatc agccacaccg atcagtttgt gacagccagt gtcattttgg aggaaaatca
    19981 tgaaagctag tccacataga ccaaccaagg ctctgattca tctgggagct attcgacaaa
    20041 atattcagca aatgggggct catatccctc aaggaacgct caagttggct gtggttaagg
    20101 ccaatgctta tggtcatgga gctgttgccg ttgccaaggc aattcaagat gatgttgatg
    20161 gcttttgcgt ttccaatatc gatgaagcca ttgaactcag acaagctgga ctcagcaagc
    20221 caatcctcat tttaggagtt tctgaaatcg aagctgttgc tctagctaaa gaatatgact
    20281 tcaccttgac agtggctgga ctggagtgga ttcaagcact cttagataag gaagtggacc
    20341 taactggatt gacagtccac ctcaagattg attcagggat gggacggatt ggttttagag
    20401 aggcaagtga ggttgagcag gctcaagatt tgctccaaca acacggtgtt tgtgttgaag
    20461 gaatctttac ccactttgct actgctgatg aggaatcaga tgactatttt aatgcccagt
    20521 tagaacggtt taaaactatt ttagctagta tgaaggaagt tccagagctg gttcatgcta
    20581 gcaattctgc aacgactctt tggcatgtag agactatttt caatgcggtt cgtatgggag
    20641 atgccatgta tggcctcaat ccaagtggag cggtcttgga tttgccttat gatttgatac
    20701 cggccttgac cttggagtct gctctggttc atgtcaagac agttccagct ggagcttgca
    20761 tgggctatgg agcaacttat caagcggata gcgagcaagt catcgcgacc gtgccaatcg
    20821 ggtatgcaga tggatggaca agagacatgc aaaatttctc tgtcttggta gatggccaag
    20881 cttgcccaat tgtcggcagg gtttcgatgg accaaatcac tattcgattg cctaagcttt
    20941 atccgctagg aaccaaggta accttgattg gctccaatgg ggataaggaa atcactgcaa
    21001 ctcaggtagc gacctaccgc gtaaccatta actatgaggt ggtttgcctc ctcagcgacc
    21061 gtattccgag agaatattat tagaaaagaa aggagtggag catgaatcta catcaaccct
    21121 tgcatgtctt gcctggtgtg ggaccaaagt cagcagaaaa atacgccaaa ctaggaattg
    21181 aaaacttgca agatctcttg ctctactttc ctttccgtta tgaagacttc aaaaccaagc
    21241 aggtgctgga gctggaagac ggtgagaagg cagttctttc tggtcaggta gtgactcctg
    21301 ctagtgtcca gtattatggt ttcaagcgca atcgcctgcg ttttagtctc aagcagggag
    21361 aggtcgtttt tgcggtgaat ttctttaacc agccctatct ggctgataaa atagagttgg
    21421 gagcaaccct tgctgtcttt ggaaaatggg accgcgctaa ggctagtctg actgggatga
    21481 aggttctggc tcaggtagaa gatgacctcc agcctgtcta tcgtctggct cagggaatca
    21541 gtcaggccag tctggtcaag gtcatcaaga cggcttttga tcagggactg gacctcttga
    21601 tagaagaaaa tctgccccag tctttactag acaaatacaa actcatgtcc cgttgtcagg
    21661 cagtccgtgc tatgcatttt ccaaagtatt tggcagaata caagcaggct cttcgccgta
    21721 taaagtttga ggaactcttt tatttccaaa tgcagctgca gatgctcaag tctgaaaata
    21781 gagttcaggg aagtggtctg gttctgaatt ggtctcagga aaaagtgaca gcagttaaag
    21841 taagtcttcc ttttgccctg acccaagctc aggaaaagag tttgcaggaa attttaactg
    21901 atatgaagtc cgaccaccac atgaatcgtc tcctacaagg ggatgtgggg agtggaaaaa
    21961 cggtagtcgc tggcttggcc atgtttgcgg cagtgacagc aggttatcag gctgccctaa
    22021 tggtaccaac agaaatcctc gcagagcaac actttgagag tttacagaac ctttttccca
    22081 atttgaaact ggctctcttg acaggttcct tgaaagctgc agaaaagaga gaagtcttgg
    22141 agaccattgc caagggtgag gctgatttga ttataggaac tcacgctctg atacaagatg
    22201 gggtggagta tgctcgtctt ggtttgatta ttatcgatga gcagcaccgt tttggtgtag
    22261 ggcaaaggcg tattttacgg gaaaaaggtg acaatccaga tgtcctcatg atgacggcga
    22321 ctcccattcc acggacgctt gccatcacag cctttggaga tatggatgtt tccattatcg
    22381 accagatgcc agcaggtcgg aagcctattg tgacgcgctg gatcaaacat gagcaactac
    22441 ctcaggtctt gacttggtta gagggggaaa ttcaaaaagg ttcccaagtc tatgtcatct
    22501 ctcctttgat tgaagaatca gaagctctag atttgaaaaa tgccattgcc ttatcagagg
    22561 agttgacgac tcattttgca ggcaaggcag aggtggctct tctacatggt aggatgaaga
    22621 gtgacgaaaa agaccagatc atgcaggatt tcaaggagag aaagacggat attctggttt
    22681 cgacgacggt tattgaggtt ggggtcaacg ttcccaatgc gactgtcatg attatcatgg
    22741 atgccgatcg cttcggtctc agtcaacttc accagcttag aggtcgtgtc ggtcgggggg
    22801 acaagcagtc ctacgctgtt ctcgttgcta atcccaagac ggattctggg aaagaccgca
    22861 tgcgtatcat gacagaaacg accaatggat ttgtccttgc ggaggaagat ttgaaaatgc
    22921 gtggttctgg tgagattttt ggaaccagac agtcaggact tccagagttc caagtggctg
    22981 atattatcga agattttccg attttagaag aagcaagaaa ggttgctagc tacattagtt
    23041 ctatagaagc ttggcaagaa gatccagagt ggcgcatgat tgcccttcat ctggaaaaga
    23101 aagaacatct ggattaagct ttctctaagg aaaacttata ctcaatgaaa atcaaagagc
    23161 aaactaggaa gctaaccgca ggttgctcaa aacactgttt tgaggttgtg gatgaaactg
    23221 acgaagtcag ctcaaaacac cgttttgagg tggcagatag aactgacgaa gtcagtaaca
    23281 tatatatacg gtaaggcgac gctgacgtgg tttgaagaga ttttcgaaga gtattaagct
    23341 agtttttagg tttggctctt atactagagt catcaaaaag aaacgaggac tctcatatga
    23401 cagtaacgat taaagtaaat taccaaacca ctttccaaaa gaaggaagca aaaaactagt
    23461 ataaacagaa gagagagcga aatgctcttt tttcgtttct aaaactactt tcagcccatc
    23521 atcctaaaag taaagaatct aaattcactt tctatttacc cttctttctt gcattgatta
    23581 catagatatg ctacagttgt ggtaacgatt acaaaataaa aggagcatgc tatgaaaaat
    23641 ccagctttgc tagaagaaat taagacctat agaggaaggg atgaggttcc ggaagacttt
    23701 gatgatttct gggatgggga agtgaaaaat gtttccacgc ttccatccta ccacttggag
    23761 gaaagagatt tccacattcc tcaagtcaag tgctatgagt taacatttga aggaagcaag
    23821 gaaggaaagg tctatgcacg cattgttctt ccaaagagtg aggagaaggt cccattaatc
    23881 ttccattttc atggttatat gggacgtggc tgggactggg ccgacatgct gggcttcacc
    23941 gtagctggtt acggtgttgt ttccatggat gtgcggggcc agtcaggtta ctcacaagac
    24001 ggcttgcgtt ctcctttagg aaataccgtg aaggggcata ttatccgtgg tgctgtggaa
    24061 ggtcgggacc acctctttta taaggatgtt tatctggata tttaccagtt ggtcgaaatt
    24121 gttgctagtc tgtctcaggt tgatgagaag cgtctttcta gctatggtgc ctcacaagga
    24181 ggggctctag ctctagttgc agcagcgctc aatcctcgaa ttcagaaaac agttgccatt
    24241 tatcccttct tgtcagactt cagacgggtg attgagattg gtaatactag cgaggcttac
    24301 gacgaacttt tccgttattt caagtttcac gaccccttcc atgaaacaga ggaggaaatc
    24361 atggcgaccc ttgcctatat cgatgtcaaa aatcttgccc atcgtatcca aggtgaggtt
    24421 aagatgatta cgggcttgga cgacgatgtt tgctatccca ttacccagtt tgcgatttat
    24481 aatcgtctga cctgcgataa aacctatcgc atcatgcctg agtatgctca cgaagccatg
    24541 aatgtatttg tcaatgacca agtctacaac tggctctgtg gaagtgagat tccttttaaa
    24601 tatctaaaat aaggagtcga ctctaagcac aaaatcttaa aaattacaaa cacgcatagt
    24661 atcaggggat taagaaaact ttatactatg cgttttatca tggaaatata gtaaaatgaa
    24721 ataagaacag gacaaatcga tcaggacagt caaatcgatt tctaacaatg ttttagaaac
    24781 aaatgtgtac tattctagtg tcaatctatt atatttatag aattttttgt tgctagattt
    24841 gtcaaattgc ttaaaataat ttttttcaga aagcaaaagc cgatacctat cgagtagggt
    24901 agttcttgct atcgtcaggc ttgtctgtag gtgttaatac ttttcaaaaa tctcttcaaa
    24961 ccacgtcagc ttcgccttgc cgtaggtatg gttactgact tcgtcagttc tatccacaac
    25021 ctcaaaacag tgttttgagc atcatgcggc tagcttctta gtttgctctt tgattttcat
    25081 tgagtataaa aacagatgag tttctgtttt ctttttatgg actataaatg ttcagctgaa
    25141 actactttca aggacattat tatataaaag aattttttga aactaaaatc tactatatta
    25201 cactatattg aaagcgtttt aaaaatgagg tataataaat ttactaacgc ttataaaaag
    25261 tgatagaatc tatttttatg tatatttaaa gatagattgc tgtaaaaata gtagtagcta
    25321 tgcgaaataa cagatagaga gaagggattg aagcttagaa aaggggaata atatgatatt
    25381 taaggcattc aagacaaaaa agcagagaaa aagacaagtt gaactacttt tgacagtttt
    25441 tttcgacagt tttctgattg atttatttct tcacttattt gggattgtcc cctttaagct
    25501 ggataagatt ctgattgtga gcttgattat atttcccatt atttctacaa gtatttatgc
    25561 ttatgaaaag ctatttgaaa aagtgttcga taaggattga gcaggaagta tggtgtaaat
    25621 agcataggct gatgtccatc atttgcttat aaagagatat tttagtttaa ttgcagcggt
    25681 gtcctggtag ataaactaga ttggcaggag tctgattgga gaaaggagag gggaaaattg
    25741 gcaccaattt gagatagttt gtttagttca tttttgtcat ttaaatgaac tgtagtaaaa
    25801 gaaagttaat aaaagacaaa ctaagtgcat tttctggagt aaatgtctta tttcagaaat
    25861 cgggatatag atatagagag gatcagtatg aatcggagtg ttcaagaacg taagtgtcgt
    25921 tatagcatta ggaaactatc ggtaggagcg gtttctatga ttgtaggagc agtggtattt
    25981 ggaacgtctc ctgttttagc tcaagaaggg gcaagtgagc aacctctggc aaatgaaact
    26041 caactttcgg gggagagctc aaccctaact gatacagaaa agagccagcc ttcttcagag
    26101 actgaacttt ctggcaataa gcaagaacaa gaaaggaaag ataagcaaga agaaaaaatt
    26161 ccaagagatt actatgcacg agatttggaa aatgtcgaaa cagtgataga aaaagaagat
    26221 gttgaaacca atgcttcaaa tggtcagaga gttgatttat caagtgaact agataaacta
    26281 aagaaacttg aaaacgcaac agttcacatg gagtttaagc cagatgccaa ggccccagca
    26341 ttctataatc tcttttctgt gtcaagtgct actaaaaaag atgagtactt cactatggca
    26401 gtttacaata atactgctac tctagagggg cgtggttcgg atgggaaaca gttttacaat
    26461 aattacaacg atgcaccctt aaaagttaaa ccaggtcagt ggaattctgt gactttcaca
    26521 gttgaaaaac cgacagcaga actacctaaa ggccgagtgc gcctctacgt aaacggggta
    26581 ttatctcgaa caagtctgag atctggcaat ttcattaaag atatgccaga tgtaacgcat
    26641 gtgcaaatcg gagcaaccaa gcgtgccaac aatacggttt gggggtcaaa tctacagatt
    26701 cggaatctca ctgtgtataa tcgtgcttta acaccagaag aggtacaaaa acgtagtcaa
    26761 ctttttaaac gctcagattt agaaaaaaaa ctacctgaag gagcggcttt aacagagaaa
    26821 acggacatat tcgaaagcgg gcgtaacggt aacccaaata aagatggaat caagagttat
    26881 cgtattccag cacttctcaa gacagataaa ggaactttga tcgcaggtgc agatgaacgc
    26941 cgtctccatt cgagtgactg gggtgatatc ggtatggtca tcagacgtag tgaagataat
    27001 ggtaaaactt ggggtgaccg agtaaccatt accaacttac gtgacaatcc aaaagcttct
    27061 gacccatcga tcggttcacc agtgaatatc gatatggtgt tggttcaaga tcctgaaacc
    27121 aaacgaatct tttctatcta tgacatgttc ccagaaggga agggaatctt tggaatgtct
    27181 tcacaaaaag aagaagccta caaaaaaatc gatggaaaaa cctatcaaat cctctaccgt
    27241 gaaggagaaa agggagctta taccattcga gaaaatggta ctgtctatac accagatggt
    27301 aaggcgacag actatcgcgt tgttgtagat cctgttaaac cagcctatag cgacaagggt
    27361 gatctataca agggtgacca attactagga aatatctact tcacaacaaa caaaacttct
    27421 ccatttagaa ttgccaagga tagctatcta tggatgtcct acagtgatga cgacgggaag
    27481 acatggtcag ctcctcaaga tattactccg atggtcaaag ccgattggat gaaattcttg
    27541 ggtgtaggtc ctggaacagg aattgtactt cggaatgggc ctcacaaggg acggattttg
    27601 ataccggttt atacgactaa taatgtatct cacttagatg gctcgcaatc ttctcgtgtc
    27661 atctattcag atgatcatgg aaaaacttgg catgctggag aagcggtcaa cgataaccgt
    27721 caggtagacg gtcaaaagat ccactcttct acgatgaaca atagacgtgc gcaaaataca
    27781 gaatcaacgg tggtacaact aaacaatgga gatgttaaac tctttatgcg tggtttgact
    27841 ggagatcttc aggttgctac aagtaaagac ggaggagtga cttgggagaa ggatatcaaa
    27901 cgttatccac aggttaaaga tgtctatgtt caaatgtctg ctatccatac gatgcacgaa
    27961 ggaaaagaat acatcatcct cagtaatgca ggtggaccga aacgtgaaaa tgggatggtc
    28021 cacttggcac gtgtcgaaga aaatggtgag ttgacttggc tcaaacacaa tccaattcaa
    28081 aaaggagagt ttgcctataa ttcgctccaa gaattaggaa atggggagta tggcatcttg
    28141 tatgaacata ctgaaaaagg acaaaatgcc tataccctat catttagaaa atttaattgg
    28201 gaatttttga gcaaaaatct gatttctcct accgaagcga aagtgaagcg aactagagag
    28261 atgggcaaag gagagatggg caaaggagtt attggcttgg agttcgactc agaagtattg
    28321 gtcaacaagg ctccaaccct tcaattggca aatggtaaaa cagcgacttt cctaacccag
    28381 tatgatagca agaccttgtt gtttgcagta gataaggaag atatcggaca ggaaattatt
    28441 ggtatagcta aaggaagcat cgaaagtatg cataatcttc ctgtaaatct agcaggtgcc
    28501 agagttcctg gcggagtaaa tggtagcaaa gcagcggtgc atgaagttcc agaatttaca
    28561 gggggagtta atggtacaga gccagctgtt catgaaatcg cagagtataa gggatctgat
    28621 tcgcttgtaa ctcttactac aaaaaaagat tatacttaca aagctcctct tgctcagcag
    28681 gcacttcctg aaacaggaaa caaggagagt gacctcctag cttcactagg actaacagct
    28741 ttcttccttg gtctgtttac gctagggaaa aagagagaac aataagagaa gaattctaaa
    28801 catttgattt tgtaa
//
LOCUS       DAVFER010000025        26262 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1105170250
            SAMEA2167659-rid19724873.denovo.025, whole genome shotgun sequence.
ACCESSION   DAVFER010000025 DAVFER010000000
VERSION     DAVFER010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2167659
            Sequence Read Archive: ERR388902
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 26262)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26262)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928716.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928716.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 04:07:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,118
            CDSs (total)                      :: 2,073
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 120
            CDSs (without protein)            :: 120
            Pseudo Genes (ambiguous residues) :: 0 of 120
            Pseudo Genes (frameshifted)       :: 67 of 120
            Pseudo Genes (incomplete)         :: 47 of 120
            Pseudo Genes (internal stop)      :: 34 of 120
            Pseudo Genes (multiple problems)  :: 23 of 120
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26262
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2167659-rid19724873.denovo.025"
                     /strain="1105170250"
                     /db_xref="taxon:1313"
     gene            169..666
                     /locus_tag="VU534_001200"
     CDS             169..666
                     /locus_tag="VU534_001200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000920162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HEU1513794.1"
                     /translation="MLKSEKQSRYQMLNEELSFLLEGETNVLANLSNASALIKSRFPN
                     TVFAGFYLFDGKELVLGPFQGGVSCIRIALGKGVCGEAAHFQETVIVGDVTTYLNYIS
                     CDSLAKSEIVVPMMKNGQLLGVLDLDSSEIEDYDAMDRDYLEQFVAILLEKTAWDFTM
                     FEEKS"
     gene            666..2321
                     /gene="dnaX"
                     /locus_tag="VU534_001201"
     CDS             666..2321
                     /gene="dnaX"
                     /locus_tag="VU534_001201"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000283769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HEU1513795.1"
                     /translation="MYQALYRKYRSQNFSQLVGQEVVAKTLKQAVEQEKISHAYLFSG
                     PRGTGKTSVAKIFAKAMNCPNQVGGEPCNNCYICQAVTDGSLEDVIEMDAASNNGVDE
                     IREIRDKSTYAPSLARYKVYIIDEVHMLSTGAFNALLKTLEEPTQNVVFILATTELHK
                     IPATILSRVQRFEFKSIKTQDIKEHIHYILEKENISSEPEAVEIIARRAEGGMRDALS
                     ILDQALSLTQGNELTTAISEEITGTISLSALDDYVAALSQQDVPKALSCLNLLFDNGK
                     SMTRFVTDLLHYLRDLLIVQTGGANTHHSSVFVENLALPQKNLFEMIRLATVSLADIK
                     SSLQPKIYAEMMTVRLAEIKSEPALSGAVENEIATLRQEVARLKQELSNVGAVPKQVA
                     PAPSRPATGKTVYRVDRNKVQSILQEAVENPDLARQNLIRLQNAWGEVIESLGGPDKA
                     LLVGSQPVAANEHHAILAFESNFNAGQTMKRDNLNTMFGNILSQAAGFSPEILAISME
                     EWKEVRAAFSAKAKSSQTEKEVEESLIPEGFEFLADKVKVEED"
     gene            2349..2543
                     /locus_tag="VU534_001202"
     CDS             2349..2543
                     /locus_tag="VU534_001202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3272 domain-containing protein"
                     /protein_id="HEU1513796.1"
                     /translation="MNKQQFIIMALFTAAETYFFNEAWMTGRYIMAAFWAILLFRNFR
                     VSYVMGKIVDVIDQHFNRKD"
     gene            2693..3463
                     /gene="sufC"
                     /locus_tag="VU534_001203"
     CDS             2693..3463
                     /gene="sufC"
                     /locus_tag="VU534_001203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000114488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HEU1513797.1"
                     /translation="MSVLEIKDLHVEIEGKEILKGVNLTLKTGEIAAIMGPNGTGKST
                     LSAAIMGNPNYEVTKGEVLFDGVNILELEVDERARMGLFLAMQYPSEIPGITNAEFLR
                     AAMNAGKEDDEKISVREFITKLDEKMELLNMKEEMAERYLNEGFSGGEKKRNEILQLL
                     MLEPTFALLDEIDSGLDIDALKVVSKGVNAMRGEGFGAMIITHYQRLLNYITPDVVHV
                     MMEGRVVLSGGPELAARLEREGYAKLAEELGYDYKEEL"
     gene            3491..4753
                     /gene="sufD"
                     /locus_tag="VU534_001204"
     CDS             3491..4753
                     /gene="sufD"
                     /locus_tag="VU534_001204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HEU1513798.1"
                     /translation="MTRENIKLFSEMHAEPSWLADLRQKAFDKIETLELPVIECVKFH
                     RWNLGDGTITENEPSANVPDFTALDHHLKLVQVGTQTVFEQTPVELAEQGVVFTDFHS
                     ALEEIPELIEEFFMSSVKYDDDKLAAYHTAYFNSGAVLYIPDNVEITEPIEGIFYQDS
                     DSNVPFNKHIMIIVGKNSKISYLERLESRGEGSDKATANITVEVIARSGAQVKFAAID
                     RLGENVTAYISRRGKLGNDASIDWAIGVMNEGNVVADFDSDLIGNGSHADLKVVALSS
                     GRQVQGIDTRVTNYGCNSIGNILQHGVILEKATLTFNGIGHIIKGAKGADAQQESRVL
                     MLSDQARSDANPILLIDENDVTAGHAASIGQVDPEDMYYLMSRGLDKATAERLVVRGF
                     LGSVIVEIPVKEVRDEMIATIEEKLSKR"
     gene            4764..5990
                     /locus_tag="VU534_001205"
     CDS             4764..5990
                     /locus_tag="VU534_001205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000887707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEU1513799.1"
                     /translation="MLDVEAIRKDFPILDQIVNDEPLVYLDNAATTQKPLVVLKAINS
                     YYEQDNANVHRGVHTLAERATASYEAARETIRKFINAGSTKEVLFTRGTTTSLNWVAR
                     FAEEILTEGDQVLISVMEHHSNIIPWQEACRKTGAELVYVYLKDGALDMEDLRAKLTD
                     KVKFVSLAHASNVLGVVNPIKEITQLAHQVGAIMVVDGAQSTPHMKIDVQDLDLDFFA
                     FSGHKMAGPTGIGVLYGKEKYLEQMSPVEFGGEMIDFVYEQFASWKELPWKFEAGTPN
                     MAGAIGLATAVDYLEKIGMDAVEAHEQELIAYVYPKLQAIEGLTIYGSQDLAQRSGVI
                     AFNLGDLHPHDLATALDYEGVAVRAGHHCAQPLLQYLEVPATARASFYIYNTKADCDK
                     LVDALQKTKEFFNGTF"
     gene            5977..6417
                     /locus_tag="VU534_001206"
     CDS             5977..6417
                     /locus_tag="VU534_001206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SUF system NifU family Fe-S cluster assembly
                     protein"
                     /protein_id="HEU1513800.1"
                     /translation="MALSKLDSLYMAVVADHSKNPHHQGKLEDAEQISLNNPTCGDVI
                     NLSVKFDAEDRLEDIAFLNSGCTISTASASMMTDAVLGKTKQEILELATIFSEMVQGQ
                     KDERQDQLGDAAFLSGVAKFPQRIKCATLAWNALKKTIENQEKQ"
     gene            6471..7883
                     /gene="sufB"
                     /locus_tag="VU534_001207"
     CDS             6471..7883
                     /gene="sufB"
                     /locus_tag="VU534_001207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HEU1513801.1"
                     /translation="MAEERVEPKPIDLGEYKFGFHDDVEPVLSTGKGLNEGVIRELSA
                     AKGEPEWMLEFRLKSYETFKKMPMQTWGADLSEIDFDDLIYYQKPSDKPARSWDDVPE
                     KIKETFERIGIPEAERAYLAGASAQYESEVVYHNMKEEFQKLGIIFTDTDSALKEYPD
                     LFKQYFAKLVPPTDNKLAALNSAVWSGGTFIYVPKGVKVDIPLQTYFRINNENIGQFE
                     RTLIIVDEGASVYYVEGCTAPTYSSNSLHAAIVEIFALDGAYMRYTTIQNWSDNVYNL
                     VTKRAKAQKDATVEWIDGNLGAKTTMKYPSVYLDGEGARGTMLSIAFANAGQHQDTGA
                     KMIHNAPHTSSSIVSKSIAKGGGKVDYRGQVTFNKNSKKSVSHIECDTIIMDDLSASD
                     TIPFNEIHNSQVALEHEAKVSKISEEQLYYLMSRGLSESEATEMIVMGFVEPFTKELP
                     MEYAVELNRLISYEMEGSVG"
     gene            complement(8114..9355)
                     /locus_tag="VU534_001208"
     CDS             complement(8114..9355)
                     /locus_tag="VU534_001208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HEU1513802.1"
                     /translation="MKKIFLTLLTVSLLGGASTAVAQDFTIAAKHAIAVEANTGKILY
                     EKDATQPVEIASITKLITVYLVYEALENGSITLSTPVDISDYPYQLTTNSEASNIPME
                     ARNYTVEELLEATLVSSANSAAIALAEKIAGSEKDFVDMMRAKLLEWGIQDATVVNTT
                     GLNNETLGDNIYPGSKKDEENKLSAYDVAIVARNLIKKYPQVLEITKKPSSTFAGMTI
                     TSTNYMLEGMPAYRGGFDGLKTGTTDKAGESFVGTTVEKGMRVITVVLNADHQDNNPY
                     ARFTATSSLMDYISSTFTLRKIVQQGDAYQDSKAPVQDGKEDTVTAVAPEDIYLIERV
                     GNQSSQSVQFTPDSKAIPAPLEAGTVVGHLTYEDKDLIGQGYITTERPSFEMVADKKI
                     EKAFFLKVWWNQFVRFVNEKL"
     gene            9458..10567
                     /locus_tag="VU534_001209"
     CDS             9458..10567
                     /locus_tag="VU534_001209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HEU1513803.1"
                     /translation="MFRRNKLFFWTTEILLLTIIFYLWRQMGSLINPFVSVLNTIMIP
                     FLLGGFFYYLTNPIVTFLNKVCKLNRLLGILITLCTLVWGMVIGVVYLLPILINQLSS
                     LIISSQTIYSRVQDLIIDLSNYPALQNLDVEATIQQLNLSYVDILQNILNSVSNSVGS
                     VLSALISTVLILIMTPVFLVYFLLDGHKFLPMLERTILKRDRLHIAGLLKNLNATIAR
                     YISGVSIDAIIIGCLAYIGYSIIGLKYALVFAIFSGVANLIPYVGPSIGLIPMIIANI
                     FTDPHRLLIAVIYMLVVQQVDGNILYPRIVGSVMKVHPITILVLLLLSSNIYGVVGMI
                     VAVPTYSILKEISKFLSHLYENHKIMKERERELAK"
     gene            11101..11448
                     /gene="ssrA"
                     /locus_tag="VU534_001210"
     tmRNA           11101..11448
                     /gene="ssrA"
                     /locus_tag="VU534_001210"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            complement(11631..11718)
                     /locus_tag="VU534_001211"
     tRNA            complement(11631..11718)
                     /locus_tag="VU534_001211"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(11682..11684),aa:Ser,seq:gga)
     gene            11880..12620
                     /locus_tag="VU534_001212"
     CDS             11880..12620
                     /locus_tag="VU534_001212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000920650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEU1513804.1"
                     /translation="MLKTERKQLILEELNQHHVVSLEKLVSLLETSESTVRRDLDELE
                     AENKLRRVHGGAELPYSLQEEETIQEKSVKNLQEKKLLAQKAASLIKEKDVIFIDAGT
                     TTAFLIHELVNKNVTVVTNSIHHAAQLVEKQIPTVMVGGNVKTATDASIGGVALNQIN
                     QLHFDRAFIGINGVDDGYYTTPDMEEGAVKRAILENAKQTYVLVDSSKIGQTCFAKVA
                     PLKRAIVITSQGHELLQVIKEKTEVIEV"
     gene            12617..13528
                     /gene="pfkB"
                     /locus_tag="VU534_001213"
     CDS             12617..13528
                     /gene="pfkB"
                     /locus_tag="VU534_001213"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015605104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HEU1513805.1"
                     /translation="MIYTVTLNPSIDYIVRLDQVKVGSVNRMDSDDKFAGGKGINVSR
                     VLKRLNIPNTATGFIGGFTGKFITDTLAEEEIETRFVQVAEDTRINVKIKADQETEIN
                     GTGPTVESVQLEELKAILSSLTAEDTVVFAGSSAKNLGNVIYKDLISLTRQTGAQVVC
                     DFEGQTLIDSLDYQPLLVKPNNHELGAIFGVKLESLDEIEKYARELLAKGAQNVIISM
                     AGDGALLVTSEGAYFAKPIKGTVKNSVGAGDSMVAGFTGEFVKSKDVVEAFKWGVACG
                     TATTFSDDLATAEFIKETYGKVEVEKR"
     gene            13525..15477
                     /locus_tag="VU534_001214"
     CDS             13525..15477
                     /locus_tag="VU534_001214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEU1513806.1"
                     /translation="MKIQDLLRKDVMLLDLQATEKTAVIDEMIKNLTDHGYVTDFETF
                     KEGILAREALTSTGLGDGIAMPHSKNAAVKEATVLFAKSNKGVDYESLDGQATDLFFM
                     IAAPEGANDTHLAALAELSQYLMKDGFADKLRQATSADQVIELFDQASEKTEELVQAP
                     ANDSGDFIVAVTACTTGIAHTYMAQEALQKVAAEMGVGIKVETNGASGVGNQLTAEDI
                     RKAKAIIIAADKAVEMDRFDGKPLINRPVADGIRKTEELINLALSGDTEVYRAANGAK
                     AATASNEKQSLGGALYKHLMSGVSQMLPFVIGGGIMIALAFLIDGALGVPNENLGNLG
                     SYHELASMFMKIGGAAFGLMLPVFAGYVAYSIAEKPGLVAGFVAGAIAKEGFAFGKIP
                     YAAGGEATSTLAGVSSGFLGALVGGFIAGALVLAIKKYVKVPRSLEGAKSILLLPLLG
                     TILTGFVMLAVNIPMAAINTAMNDFLGGLGGGSAVLLGIVLGGMMAVDMGGPVNKAAY
                     VFGTGTLAATVSSGGSVAMAAVMAGGMVPPLAIFVATLLFKDKFTKEERNSGLTNIIM
                     GLSFITEGAIPFGAADPARAIPSFILGSAVAGGLVGLTGIKLMAPHGGIFVIALTSNA
                     LLYLVSVLVGAIVSGVVYGYLRKPQA"
     gene            15641..17866
                     /locus_tag="VU534_001215"
     CDS             15641..17866
                     /locus_tag="VU534_001215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000908822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HEU1513807.1"
                     /translation="MLISLGIAILLIFAAFKLGAAGITLYNLIRLLVGSLAYLAIFGL
                     LIYLFFFKWIRKQEGLLSGFFTIFAGLLLIFEAYLVWKYGLDKSVLKGTMAQVVTDLT
                     GFRTTSFAGGGLIGVALYIPTAFLFSNIGTYFIGSILILVGSLLVSPWSVYDIAEFFS
                     RGFAKWWEGHERRKEERFVKQEEKARQKAEKEARLEQEETEKALLDLPPVDMETGEIL
                     TEEAVQNLPPIPEEKWVEPEIILPQAELKFPEQEDDSDDEDVQVDFSAKEALEYKLPS
                     LQLFAPDKPKDQSKEKKIVRENIKILEATFASFGIKVTVERAEIGPSVTKYEVKPAVG
                     VRVNRISNLSDDLALALAAKDVRIEAPIPGKSLIGIEVPNSDIATVSFRELWEQSQTK
                     AENFLEIPLGKAVNGTARAFDLSKMPHLLVAGSTGSGKSVAVNGIIASILMKARPDQV
                     KFMMVDPKMVELSVYNDIPHLLIPVVTNPRKASKALQKVVDEMENRYELFAKVGVRNI
                     AGFNAKVEEFNSQSEYKQIPLPFIVVIVDELADLMMVASKEVEDAIIRLGQKARAAGI
                     HMILATQRPSVDVISGLIKANVPSRVAFAVSSGTDSRTILDENGAEKLLGRGDMLFKP
                     IDENHPVRLQGSFISDDDVERIVNFIKTQADADYDESFDPGEVSENEGEFSDGDAGGD
                     PLFEEAKSLVIETQKASASMIQRRLSVGFNRATRLMEELEIAGVIGPAEGTKPRKVLQ
                     Q"
     gene            complement(17911..18339)
                     /locus_tag="VU534_001216"
     CDS             complement(17911..18339)
                     /locus_tag="VU534_001216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1513808.1"
                     /translation="MSNYRRTSKPKTEHIKKGFTVFQKTVATIASILGLITASITIMN
                     ALDNNKNIKKEPTTSQTTTIVKEIQKESPKENTSPTKETNTSQEKTQQEETPKSSVKE
                     EKKEDQKTATQDSSTPASSKPATENEKQSNAPTSENKSNQ"
     gene            18477..19619
                     /locus_tag="VU534_001217"
     CDS             18477..19619
                     /locus_tag="VU534_001217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000638948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEU1513809.1"
                     /translation="MIYFDNSATTKPYPEALETYMQVASKILGNPSSLHRLGDQATRI
                     LDASRQQIADLIGKKSDEIFFTSGGTEGDNWLIKGVAFEKAQFGKHIIVSAIEHPAVK
                     ESALWLKSQGFEVDFAPVDKKGLVDVEALAGLIRHDTILVSIMAVNNEIGSIQPIEAI
                     SEFLADKPTISFHVDAVQALAKIPTEKYLTERVDCATFSSHKFHGVRGVGFVYIKSGK
                     KITPLLTGGGQERDYRSTTENVAGIAATAKALRLSMEKLDIFRSKTGQMKAVIRQALL
                     NYPDIFVFSDEENFAPHILTFGIKGVRGEVIVHAFEDYDIFISTTSACSSKAGKPAGT
                     LIAMGVDKDKAKSAVRLSLDLENDMSQVEQFLTKLKLIYNQTRKVR"
     gene            19628..20842
                     /gene="thiI"
                     /locus_tag="VU534_001218"
     CDS             19628..20842
                     /gene="thiI"
                     /locus_tag="VU534_001218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001200101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 4-thiouridine(8) synthase ThiI"
                     /protein_id="HEU1513810.1"
                     /translation="MQYSEIMIRYGELSTKGKNRMRFINKLRNNISDVLSIYTQVKVT
                     ADRDRAHAYLNGADYTAVAESLKQVFGIQNFSPVYKVEKSVEVLKSSVQEIMRDIYKE
                     GMTFKISSKRSDHNFELDSRELNQTLGGAVFEAIPNVQVQMKSPDINLQVEIREEAAY
                     LSYETIRGAGGLPVGTSGKGMLMLSGGIDSPVAGYLALKRGVDIEAVHFASPPYTSPG
                     ALKKAQDLTRKLTKFGGNIQFIEVPFTEIQEEIKAKAPEAYLMTLTRRFMMRITDRIR
                     EVRNGLVIINGESLGQVASQTLESMKAINAVTNTPIIRPVVTMDKLEIIDIAQEIDTF
                     DISIQPFEDCCTIFAPDRPKTNPKIKNAEQYEARMDVEGLVERAVAGIMITEITPQAE
                     KDEVDDLIDNLL"
     gene            20977..21801
                     /locus_tag="VU534_001219"
     CDS             20977..21801
                     /locus_tag="VU534_001219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001076725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEU1513811.1"
                     /translation="MNQSYFYLKMKEHKLKVPYTGKERRVRILLPKDYEKDTDRSYPV
                     VYFHDGQNVFNSKESFIGHSWKIIPAIKRNPDISRMIVVAIDNDGMGRMNEYAAWKFQ
                     ESPIPGQQFGGKGVEYAEFVMEVVKPFIDETYRTKADCQHTAMIGSSLGGNITQFIGL
                     EYQDQIGCLGVFSSANWLHQEAFNRYFECQKLSPDQRIFIYVGTEEADDTDKTLMDGN
                     IKQAYIDSSLCYYHDLIAGGVHLDNLVLKVQSGAIHSEIPWSENLPDCLRFFAEKW"
     gene            21823..22562
                     /locus_tag="VU534_001220"
                     /pseudo
     CDS             21823..22562
                     /locus_tag="VU534_001220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000546805.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
     gene            22575..23741
                     /locus_tag="VU534_001221"
     CDS             22575..23741
                     /locus_tag="VU534_001221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001108652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HEU1513812.1"
                     /translation="MNYLVISPYYPQNFQQFTIELANKGITVLGIGQESYEQLDEPLR
                     NSLTEYFRVDNLENIDEVKRAVAFLFYKHGPIGRIESHNEYWLELDATLREQFNVFGA
                     KPEDLKKTKYKSEMKKLFKKAGVPVVPGAVIKTEADVDQAVKEIGLPMIAKPDNGVGA
                     AATFKLETEDDINHFKQEWDHSTLYFFEKFVTSSEICTFDGLVDKDGKIVFSTTFDYA
                     YTPLDLMIYKMDNSYYVLKDMDPKLRKYGEAIVKEFGMKERFFHIEFFREGDDYITIE
                     YNNRPAGGFTIDVYNFAHSLDLYRGYAAIVAGEEFPASDFETQYCLATSRRANAHYVY
                     SEEDLLAKYSQQFKVKKVMPAAFAELQGDYLYMLTTPSRQEMEQMIADFGQRQE"
     gene            24249..25742
                     /locus_tag="VU534_001222"
     CDS             24249..25742
                     /locus_tag="VU534_001222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent DNA methyltransferase"
                     /protein_id="HEU1513813.1"
                     /translation="MITGELKNKIDQLWEILWTEGNANPLTNIEQLTYLLFMKDLDSV
                     ELGRESDAEFLGIPYEGVFPKDKPEYRWSTFKNIGDAQEVYRLMTQEIFPFIKNLKGD
                     TDDTAFSRYMREAIFQINKPATLQKAISILDVFPTRGLDVDFDNDKQSITDIGDIYEY
                     LLSKLSTAGKNGQFRTPRHIIDMMVELMQPTIKDIISDPAMGSAGFLVSASRYLKRKK
                     DEWETNTDNINHFHNQMFHGNDTDTTMLRLGAMNMMLHGVENPQISYLDSLSQDNEEA
                     DKYTLVLANPPFKGSLDYNSTSNDLLATVKTKKTELLFLSLFLRTLKPGGRAAVIVPD
                     GVLFGSSKAHKGIRQEIVENHKLDAVISMPSGVFKPYAGVSTAILIFTKTGNGGTDKV
                     WFYDMKADGLSLDDKRQPISDNDIPDIIERFHHLEKEAERQRTDQSFFVPVAEIKEND
                     YDLSINKYKEIEYEKVEYEPTEVILKKINDLEKEIQAGLAELEKLLK"
     gene            25755..>26262
                     /locus_tag="VU534_001223"
     CDS             25755..>26262
                     /locus_tag="VU534_001223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000756162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEU1513814.1"
                     /translation="MKKVKLGEVLSLKKGKKATVLAEQTTLSQRYIQIDDLRNNNNLK
                     FTESLNMTEALPDDILIAWDGANAGTVGYGLSGAVGSTITVLKKNERYKEKIISDYLG
                     VFLESKSQYLRDHSTGATIPHLNKNILLDLQLELLGIEEQENIICILNTIKRLITKRK
                     FQLDELNLL"
BASE COUNT         7831 a         4840 c         5772 g         7819 t
ORIGIN      
        1 gtcgcttttc attataggtc atatgggact ttttttctac aataaaatag gctccataat
       61 atctataagg gatttaccca ctacaaatat tatagagcca aaaatccttt gtttactaaa
      121 caagggattt ttcttttgtc tctgctcctt ttttgatata atagttctat gttaaaatca
      181 gaaaaacaat cacgttatca aatgttaaat gaagaattgt ccttcctatt ggaaggcgaa
      241 accaatgttt tggctaatct ttccaacgcc agtgctctca taaaatcacg ttttcctaat
      301 accgtatttg caggctttta tttgttcgat ggaaaggaat tggttttagg ccccttccaa
      361 ggaggtgttt cctgcatccg tattgcacta ggcaagggtg tttgtggtga ggcagctcac
      421 tttcaggaaa ctgttattgt tggagatgtg acgacctatc tcaactatat ttcttgtgat
      481 agtctagcta aaagtgaaat tgtggtgccg atgatgaaga atggtcagtt acttggagtt
      541 ctggatctgg attcttcaga gattgaggat tacgatgcta tggatcgaga ttatttggaa
      601 caatttgtcg ctattttgct tgaaaagaca gcatgggact ttacgatgtt tgaggaaaaa
      661 tcttaatgta tcaagcactt tatcgaaaat atagaagtca aaacttctcc cagttagttg
      721 gtcaagaagt tgtggctaag actcttaaac aagcggtgga gcaagagaaa ataagtcacg
      781 cttatctttt ttctggtcct cgtggaacgg gaaaaaccag tgttgctaaa atctttgcca
      841 aggctatgaa ctgtcccaat caagtgggtg gcgaaccttg caataactgc tatatttgtc
      901 aagcagtgac ggacggtagt ttagaagatg tcattgaaat ggatgcagct tctaataatg
      961 gggtagatga aattcgcgaa attcgtgata aatctaccta tgcgcctagc cttgctcgtt
     1021 ataaggttta tatcatagat gaggttcaca tgctgtctac aggggctttt aatgccctcc
     1081 taaagacgct ggaagaacca acacagaatg tagtctttat tttggccact actgaattgc
     1141 acaagattcc tgctactatt ctatcccgtg tgcaacgttt tgagtttaaa tcaattaaga
     1201 cacaggatat taaggaacat attcactata tcttagaaaa agaaaatatc agttctgaac
     1261 cagaggctgt ggaaatcatt gccagacggg cggaaggtgg aatgcgggac gccttgtcta
     1321 ttttggatca agccctgagt ttgacacagg gaaatgagct gacgactgct atctctgaag
     1381 aaattactgg caccattagc ctatcagcct tggatgatta tgtggcggcc ttgtctcaac
     1441 aggatgttcc caaagctttg tcttgcttga atcttctttt tgacaatggt aagagcatga
     1501 ctcgttttgt gaccgatctt ttgcactatt taagagactt gttaattgtt caaacagggg
     1561 gagcaaatac tcatcatagt tcagtctttg tagaaaattt ggcacttcct caaaaaaatc
     1621 tgtttgaaat gattcgctta gcaacagtga gtttagcaga tattaagtct agtttgcaac
     1681 ccaagattta tgctgaaatg atgaccgtcc gtttggcgga aatcaagtcc gaaccagctc
     1741 tatcaggagc ggttgaaaat gaaattgcta cgctgagaca ggaagttgcc cgtctcaaac
     1801 aagagctttc taatgtaggt gcggttccta aacaagttgc accagctcct agtcgaccag
     1861 ctacgggcaa aacagtctat cgtgtcgatc gcaataaagt gcaatctatc ttacaagagg
     1921 ccgtcgaaaa tcctgattta gcacgtcaaa atttaattcg tttgcagaat gcctggggag
     1981 aggtaattga aagtctaggt gggccggaca aggctctgct agttggttct caaccggttg
     2041 ctgccaatga acaccatgct attcttgctt ttgagtctaa cttcaatgct ggtcaaacta
     2101 tgaaacgaga caatctcaat accatgtttg gtaatatcct cagtcaggcg gcaggttttt
     2161 cacctgagat tttagctatt tccatggagg aatggaaaga agttcgcgca gccttttcag
     2221 ccaaagccaa atcttctcaa actgaaaaag aagtagaaga aagcctgatt ccagaaggat
     2281 ttgaattttt ggctgataaa gtgaaggtag aggaagacta aagaaagatt tcatgataca
     2341 ataagtttat gaataaacaa caatttatta ttatggcgct gtttacagct gctgagacct
     2401 attttttcaa tgaagcctgg atgactggcc gctatattat ggcagccttt tgggcaattt
     2461 tactctttag aaatttccga gtcagttatg tgatgggcaa aatcgttgat gtcatcgatc
     2521 agcattttaa taggaaagac tagccctcag cttccagaca aaatcaaagc cttttaggct
     2581 tttttttgtt atactagaaa agtatattta tagaattttt gctctatttc tggggaaatc
     2641 agacgttttt ctagtaagta ctgtaaaagt tttgaaaaag aaaggaacta tcatgtcagt
     2701 attagagatc aaagatcttc acgttgagat tgaaggaaaa gaaattttaa aaggggttaa
     2761 cctgaccctg aaaacaggag aaattgccgc tatcatggga ccaaatggta caggtaaatc
     2821 gactctttct gccgctatca tgggaaatcc aaactatgaa gtaactaaag gtgaagtttt
     2881 gtttgatggc gtaaacatcc ttgagttgga agtggatgag cgtgcgcgta tgggactttt
     2941 ccttgctatg caatacccat cagaaatccc tggaattacc aatgctgagt ttcttcgtgc
     3001 cgctatgaat gcgggtaaag aagatgatga gaagatttca gttcgtgagt ttattactaa
     3061 gctagatgaa aaaatggaat tgctcaacat gaaagaagaa atggcagagc gttacctcaa
     3121 cgaaggcttc tctggtggtg agaaaaaacg caatgaaatt cttcaacttt tgatgttgga
     3181 gccaacattt gctcttttgg acgagattga ctcaggtctt gatattgacg ctcttaaagt
     3241 tgtgtctaaa ggtgtcaatg ccatgcgtgg tgaaggtttt ggtgctatga tcatcactca
     3301 ctaccaacgt cttttgaact atatcacacc tgatgtggta cacgtgatga tggaaggtcg
     3361 tgttgtcctt tctggtggtc cagaattggc tgcgcgtttg gaacgtgaag gatacgcaaa
     3421 attagctgaa gaacttggct acgactacaa ggaagaattg taattccctc gtatctttta
     3481 ggagaagtaa atgactagag aaaatattaa acttttttca gaaatgcacg ctgaaccaag
     3541 ctggttggct gatctccgtc aaaaagcttt tgacaagatt gagactttgg aattaccagt
     3601 tattgagtgt gtcaaattcc accgttggaa tctgggtgat ggaacgatta cagaaaatga
     3661 gccatcagca aatgttccag atttcacagc tttagatcat cacttgaagt tggtgcaagt
     3721 aggaactcaa actgttttcg aacaaactcc agttgagtta gctgaacagg gtgttgtctt
     3781 cacagacttt cactcagctt tagaagaaat tccagagctg atcgaagaat tcttcatgtc
     3841 atctgttaag tatgatgatg acaagttggc ggcttaccac acagcttact ttaacagtgg
     3901 tgctgtactc tatattccag ataacgtaga aatcacagag ccaattgaag gaattttcta
     3961 ccaagatagc gatagcaatg tgccgtttaa caagcatatt atgattatcg ttggtaaaaa
     4021 ttctaagatt agttatctgg agcgtttaga gtcacgcggt gaaggaagtg acaaagcaac
     4081 tgccaatatc acagtggaag tgattgcacg ttctggtgcg caagtcaagt ttgctgctat
     4141 cgaccgtcta ggtgaaaacg tcactgccta cattagccgt cgtggtaaat taggcaacga
     4201 tgcaagtatt gactgggcta tcggtgtcat gaacgaagga aatgtcgttg ctgattttga
     4261 tagtgacttg attggtaatg gtagccatgc tgacctcaag gttgtagctc tttcaagtgg
     4321 tcgtcaggta caagggattg atactcgtgt aactaactat ggctgcaact caatcggaaa
     4381 cattctacaa catggggtta tccttgaaaa agcaactttg actttcaatg gtatcggcca
     4441 catcatcaag ggtgctaagg gagcagatgc gcaacaagag agccgtgttc tcatgctttc
     4501 agaccaagcg cgttcagatg ctaacccaat tcttttgatt gatgaaaatg acgtaactgc
     4561 aggccatgca gcctctattg gtcaggtaga tccagaagat atgtactacc tcatgagtcg
     4621 tggcttggat aaggcaactg cagagcgttt ggttgttcgt ggtttccttg gatctgttat
     4681 cgtggagatt ccagtcaagg aagttcgtga tgaaatgatt gcaactatcg aagagaaatt
     4741 gtcaaaacgc taaggggcag cctatgttag atgtagaagc gattcgcaag gattttccaa
     4801 ttttagatca gattgtcaat gatgaacctc tggtctatct ggacaatgct gcgacgacac
     4861 aaaaaccact agtagttctg aaagctatta acagctacta tgagcaggac aatgccaatg
     4921 ttcaccgtgg tgtccatacc ttagcggaac gagcgacagc ttcttatgaa gctgctcgtg
     4981 aaaccattcg taagtttatt aatgcaggct ctacaaagga agttctcttt accagaggaa
     5041 cgacaaccag ccttaactgg gtggcacgct ttgctgagga aattctcact gagggagacc
     5101 aggtcttgat ttcagtaatg gaacaccatt ctaatatcat tccatggcag gaagcttgtc
     5161 gaaagactgg agcagagctt gtctatgtct atcttaaaga cggtgccttg gatatggagg
     5221 atttgcgagc taaattgact gataaggtta aatttgtttc cctagctcat gcctccaatg
     5281 ttcttggtgt ggtcaatccg atcaaggaaa tcactcaatt agcccaccaa gttggggcaa
     5341 ttatggtagt ggatggtgct caatctacac ctcatatgaa gattgatgtc caggacttgg
     5401 atctggactt tttcgccttt tcgggtcaca agatggctgg tccgactggt atcggtgtcc
     5461 tttacggcaa agaaaagtat cttgagcaaa tgtctccagt agaatttggc ggcgagatga
     5521 ttgattttgt ctacgagcaa tttgctagtt ggaaggaatt gccttggaaa tttgaggctg
     5581 gaacgccaaa tatggcagga gctattggac ttgcgactgc agttgattat ctggaaaaga
     5641 ttggtatgga tgccgttgaa gctcatgaac aggaattgat tgcgtacgtc tatccaaaac
     5701 tgcaggcaat tgagggattg accatttacg gttctcagga tttggctcaa cgttcgggtg
     5761 ttattgcctt taacctaggt gatctccatc ctcacgatct tgcgacggct ctggattatg
     5821 aaggagtggc tgttcgtgct ggtcaccatt gtgcgcaacc cttgcttcag tatttggaag
     5881 tcccagcaac agctcgtgca agtttttata tctacaatac caaggcagat tgcgacaaac
     5941 tagtcgatgc cctacaaaag acaaaggagt ttttcaatgg cactttctaa actagatagc
     6001 ctttatatgg cagtggtagc agaccattcg aaaaatccac atcaccaagg gaagttagaa
     6061 gatgctgagc aaatcagtct caacaatccg acttgtgggg atgtcatcaa cctctctgtc
     6121 aagtttgatg cagaggaccg tttggaagat attgcttttc taaattcagg atgcacgatt
     6181 tcaactgctt ctgctagtat gatgacagat gccgttttag gaaaaaccaa acaagaaatt
     6241 ttagaactgg cgactatttt ttctgaaatg gttcaagggc aaaaagatga gcgtcaagac
     6301 caacttggag acgcggcatt cttgtcaggt gttgccaaat tccctcaaag aatcaagtgt
     6361 gcaaccctag cttggaatgc ccttaagaaa acaattgaaa atcaagaaaa acagtaagac
     6421 aagtttcttt tgtcttatga attattagaa atgaagaaag aaaggatact atggctgaag
     6481 aaagagtaga accaaaacca attgaccttg gtgaatataa atttggtttc catgacgatg
     6541 tagagcctgt cttatcgaca ggaaaaggac tcaacgaagg tgttattcgt gaattatctg
     6601 ctgctaaggg tgagcctgag tggatgttgg agttccgttt gaagtcttat gaaaccttca
     6661 aaaaaatgcc catgcaaact tggggagcag acttgtcaga gattgacttt gatgacttaa
     6721 tctactacca aaaaccatct gacaaaccag cccgttcttg ggatgatgta cctgaaaaga
     6781 ttaaagaaac ctttgaacgt atcgggattc cagaagctga acgtgcttat ttagcagggg
     6841 cttctgccca gtacgagtca gaagtggttt accacaacat gaaggaagag ttccaaaaat
     6901 taggtattat ctttacagat acagattccg cactcaagga atacccagac ttatttaaac
     6961 aatactttgc gaagttggta ccgccgacag ataacaagtt ggcagccctc aactcagcag
     7021 tatggtcggg tggaactttt atctacgtgc caaaaggtgt caaggtagat attccacttc
     7081 aaacttattt ccgtatcaat aacgaaaata taggtcagtt cgaacgtacc ttgattatcg
     7141 ttgatgaggg agcaagcgtc tactacgtag aaggatgtac agcaccaaca tattcaagca
     7201 atagcttaca cgctgccatt gtagaaattt ttgctttgga cggagcttat atgcgttata
     7261 caactatcca aaactggtct gataacgtct ataacttggt aacaaagcgt gctaaggctc
     7321 aaaaggatgc cactgttgag tggattgatg gaaacttggg tgccaaaacg actatgaaat
     7381 atccatctgt ttaccttgat ggagaaggag cgcgtggtac catgctctct atcgcctttg
     7441 ctaatgcagg gcaacaccaa gacacgggtg ctaagatgat tcacaatgct ccacatacca
     7501 gctcgtctat tgtgtctaaa tccatcgcta aaggtggagg aaaggttgac taccgtggac
     7561 aagtcacctt taacaagaac tctaagaaat ctgtttccca cattgaatgt gataccatta
     7621 tcatggatga cttgtcagca tcagatacta ttccatttaa tgaaattcac aactcgcaag
     7681 tggctttgga acacgaagcc aaagtatcta agatttcaga agagcaattg tattatctca
     7741 tgagccgtgg attgtcagaa tctgaggcaa ctgaaatgat tgtcatggga tttgtagaac
     7801 cctttacaaa agaacttcca atggaatacg cagttgagct gaaccgcttg attagctatg
     7861 aaatggaggg atcagttgga taaaatttga ttttatactc ttcgaaaatc tcttcaaacc
     7921 acgtcagcat cgccttaccg tatgtatggt tactgacttc gtcagtttca tctacaacct
     7981 caaaacagtg ttttgagcaa cctgcggcta gcttcctagt ttgttctttg attttgagta
     8041 ttagatttac tcaaaatcaa ggattttgaa gatgaacttg tatcaaaaaa tcgcggttta
     8101 aaatcgcgat tttttataat ttctcgttaa caaagcggac aaactgattc caccaaactt
     8161 ttaagaagaa ggctttttca attttcttgt ctgctaccat ttcgaaacta gggcgctctg
     8221 tggtgatgta accttgacca atcaagtcct tgtcttcata agtcaaatgg ccaaccactg
     8281 ttccagcttc aagtggtgct gggattgctt tggaatcagg tgtgaattga acagattggg
     8341 aagattgatt cccaacacgt tcgattagat agatatcctc tggagccact gcagttactg
     8401 tatcttcttt tccatcttgt acaggggctt tgctatcttg ataggcatcg ccttgttgaa
     8461 cgattttgcg aagtgtaaat gtagaagaaa tataatccat tagggaagat gtagctgtaa
     8521 atcgagcgta aggattattg tcttgatgat ctgcatttaa aacaactgtg atgactctca
     8581 tgcctttttc gacagtagta ccaacaaaag actctccagc cttatctgtt gttcctgttt
     8641 ttagcccatc aaaaccacca cggtaagcag gcataccttc taacatgtag ttggttgaag
     8701 tgattgtcat cccagcaaaa gtagaagaag gttttttggt gatttctaag acttgtgggt
     8761 attttttgat gaggttgcga gcaacgatag cgacatcata agcactaagc ttattttcct
     8821 catctttttt agaacctggg taaatgttat cccctagagt ttcattgtta agacctgtcg
     8881 tattgacaac agtggcatcc tgaattcccc attccaagag ttttgcccgc atcatatcga
     8941 cgaaatcttt ttctgagcca gcaattttct cagctagggc aatagcggcg ctgttggcac
     9001 tagataccag agttgcttca agcaactctt cgacagtata attacgggcc tccataggaa
     9061 tattactggc ttcagaattt gtcgtcaatt gataaggata atcagaaata tctacaggag
     9121 tggagagggt aatacttccg ttttccaaag cttcatagac cagataaaca gtaatcaatt
     9181 ttgttatgga agcaatttcg acaggttgcg ttgcatcctt ctcatagaga attttaccag
     9241 tatttgcctc aacagcaatc gcatgtttag cggcaatggt aaaatcttga gcaacagcag
     9301 tagaagcacc ccctaaaaga gagacagtta acaaagttaa aaatattttt ttcatagtag
     9361 tcttattcta tcataaagaa aaaaaatatt cttgctttaa taattcatct gttaagcttt
     9421 ttgaaaatat ggtaaaataa agtaagggag gtaactcatg tttcgtagaa ataaattatt
     9481 tttttggacc acagaaattt tactcttaac catcatcttt tacctatgga gacagatggg
     9541 gtctttgatt aacccttttg ttagcgtgct taatacaatt atgattccat ttttattagg
     9601 gggctttttt tattatttga caaaccctat tgttactttc ttaaataaag tctgtaaact
     9661 caatcgtttg cttggtattt taattacctt gtgtactttg gtctggggaa tggtcatagg
     9721 tgttgtctat ctcttaccta ttttgattaa tcagttatct agtttgatta tatctagtca
     9781 aactatttat agtcgagtac aagacttaat catagactta tctaattatc ctgcgctcca
     9841 gaatttggat gtagaagcta caattcagca gttaaactta tcctatgttg atattcttca
     9901 aaatatccta aatagcgtat caaatagtgt ggggagcgtc ttgtcagctc ttatcagtac
     9961 tgttttgatt ttgattatga ctccagtttt tttggtttat ttcttattag atggacataa
    10021 attcttgccc atgcttgaaa gaacgattct aaagagggat cgcttgcata ttgcaggctt
    10081 attaaagaat ttaaatgcga cgattgctcg ctatattagt ggagtttcga ttgacgcaat
    10141 cattataggt tgtttggctt atattggcta tagtattatt ggtttaaaat atgctttagt
    10201 ttttgccatt ttttctggtg tagccaattt aattccttat gtggggccaa gtattggttt
    10261 gattcctatg atcatcgcaa atatattcac tgatccccat agactgctga ttgcagtgat
    10321 ttatatgctt gttgttcagc aggtagatgg caatatctta tatcctcgaa tcgtaggaag
    10381 tgttatgaag gttcatccaa tcacgatttt agttttactt ttgttgtcaa gcaatatcta
    10441 tggtgtagtt ggaatgattg tcgcagtgcc aacctattct atcttgaaag aaatttctaa
    10501 gttcttatcc catttgtatg aaaatcataa aataatgaaa gaacgagaaa gagaattagc
    10561 taagtaaaag tcaggagaac cctgattttt ctttactgga agtggccttt agattagaag
    10621 actgaaaata agttaaagtc ttaaactaat tttcacagct aagaatagta gaagttaatc
    10681 tgataaaaat cgaaaaaacc agtggaattc tgtgtcaggg taagttccac tggttttcat
    10741 agtctattaa agttcgaatg aaacctattt atagtagatt gaaactagaa tagtacacct
    10801 ctaattctaa aacattgtta gaaatcgatt tgactgtcct gatctattcg ttctattctt
    10861 atttcatttt actatatttt ggtgcaataa gtgaaaagta gtccgaataa tataaggatt
    10921 gattttatag tttttaaact caaatgaatt gaaataaaga gagtacgaaa attctcatct
    10981 gaaagtattt tagaataatt ctcttcgtga atttcttcaa aacagatagc ttcatcttag
    11041 gtatgtgatt tctttttgca tttttgagtt agataaggta taatgatttt attgtctttt
    11101 ggggtcgtta cggattcgac aggcattatg aggcatattt tgcgactcgt gtggcgacgt
    11161 aaacgctcag ttaaatataa ctgcaaaaaa taacacttct tacgctctag ctgcctaaaa
    11221 accagcaggc gtgacccgat ttggattgct cgtgttcaat gacaggtctt attattagcg
    11281 agatacgatt aagccttgtc tagcggtttg ataagagatt gatagactcg cagtttctag
    11341 acttgagtta tgtgtcgagg ggctgttaaa ataatacata acctatggtt gtagacaaat
    11401 atgttggcag gtgtttggac gtgggttcga ctcccaccgg ctccattatt cctttgcatt
    11461 cttttgcatt ccttggtaaa acgttgttaa atcaacgttt tttattttta tctttggtat
    11521 tcctttgcat tcttttgcta aaaagggagt cacaaacaga ccctatttta aaaaaaggat
    11581 agaaaaaagg atacaacatt tgtcgcatcc taaaaataat cttttttcga cggaagacat
    11641 gggattcgaa cccacgcacg ctattacacg cctaccgcgt ttccaacacg gcctcttaag
    11701 cctcttgagt aatcttccaa tacttactca aatagtctac cataaaggct cttatcttgc
    11761 aataaaaatt ctagaaataa gaaaaatgat agattttgaa agaaaatgat aaaaaatgct
    11821 tgacttcgaa agaaagtatg atagaatgaa tagtgtaaac gataacagga ggtgattcag
    11881 tgttaaaaac agaacgtaaa caactaattt tagaggagtt aaatcaacat catgtagttt
    11941 ctctagaaaa attagttagt ttgctagaaa cgtcagaatc aacggttcga agagacttgg
    12001 atgagttgga agcggaaaac aagcttcgtc gtgtgcatgg tggagcagaa ctcccctact
    12061 ccttacagga agaagaaacc attcaagaaa aatctgtcaa aaaccttcaa gaaaagaaat
    12121 tgctggctca gaaagcagcc tctctcatta aagaaaaaga tgtcatcttt atcgatgctg
    12181 gaacaacaac tgcttttttg attcatgaat tggtcaataa gaatgttaca gttgtgacca
    12241 actccattca ccatgccgct cagttggttg aaaagcagat tccaactgtc atggttggag
    12301 gaaacgtcaa gacggcgaca gatgctagta tcgggggcgt tgctcttaac cagattaacc
    12361 aattgcactt tgaccgtgcc tttatcggaa taaatggtgt tgacgatggc tattatacga
    12421 ctcctgatat ggaggaggga gctgtgaaaa gagctatttt ggagaatgcc aagcagacct
    12481 acgtcttggt ggattcgtca aaaattggac aaacttgctt tgccaaggta gccccactca
    12541 aacgcgctat cgttatcact agtcaagggc atgagctctt gcaggttatt aaggagaaaa
    12601 cggaggtaat agaagtatga tttatacagt cacactcaat ccatccattg actatatcgt
    12661 tcgtttggac caagtcaaag ttggtagtgt caatcgtatg gacagtgatg ataagtttgc
    12721 tggtgggaaa ggaatcaatg tcagccgtgt cttgaaacgt ttgaatatac caaatacagc
    12781 gacgggattt atcggtggct ttactggtaa atttatcaca gatactttag cagaggaaga
    12841 aatcgagaca cgttttgtcc aggtggcaga agatactcgt atcaatgtta aaatcaaagc
    12901 agaccaagaa acagaaatca acggaacggg tccaactgtt gaatcggttc agctagaaga
    12961 attgaaagct attttatcta gtctgacagc agaagataca gttgtctttg caggttcaag
    13021 tgctaaaaat ctaggcaatg ttatctataa ggatttgatt tccttgacgc gccagactgg
    13081 tgcgcaagtg gtctgtgact ttgaaggaca gaccttaatt gatagtttgg actaccagcc
    13141 tcttcttgta aaaccaaaca atcatgaact tggagcgatt tttggggtta aactcgaaag
    13201 tttagatgaa attgagaaat acgctcgtga gttactggct aagggtgctc aaaatgttat
    13261 tatctctatg gctggtgatg gtgcccttct tgtcacatct gagggagctt acttcgctaa
    13321 accaatcaaa ggaacagtca aaaattcagt tggagctggt gattctatgg ttgctggatt
    13381 cacaggtgaa tttgtcaaat caaaagacgt agtagaagcc ttcaaatggg gagtggcttg
    13441 cggaacggca actaccttct cagatgactt ggcaacggcg gaatttatta aagaaacata
    13501 tggaaaagtt gaggtagaaa aacgatgaaa attcaagacc tattgagaaa agatgtcatg
    13561 ttgctagatt tgcaggcaac tgaaaaaaca gctgtcatcg acgagatgat taaaaatttg
    13621 acagaccacg gttatgtaac agattttgaa acatttaaag aaggaatttt ggcgcgtgaa
    13681 gctttgactt ctactggttt gggtgatgga atcgcaatgc ctcacagcaa aaacgctgct
    13741 gtcaaagaag cgacagttct atttgctaag tcaaataagg gtgttgacta cgagagcttg
    13801 gatggacaag caactgacct cttcttcatg attgcagctc cagaaggtgc caatgatact
    13861 cacttggcag ccttggcaga attgtctcaa tacttgatga aagacggttt tgcagacaaa
    13921 cttcgtcaag caacatctgc agaccaagtt atcgaacttt ttgaccaagc ttcagaaaaa
    13981 actgaggaac ttgttcaagc acctgctaat gactctggtg actttatcgt agctgttaca
    14041 gcttgtacaa caggtattgc ccacacttac atggcccaag aagcccttca aaaagtagct
    14101 gctgaaatgg gggttggtat caaggtcgaa accaacggtg ctagcggtgt tggaaatcaa
    14161 ctaactgcag aagatatccg taaggctaaa gctattatca ttgcagcaga caaggccgtt
    14221 gaaatggatc gatttgatgg aaaaccattg atcaatcgtc cagttgctga cggtatccgt
    14281 aagacagaag agctaattaa cttggctctt tcaggagata ctgaagtcta ccgtgccgct
    14341 aatggtgcca aagctgcaac agcctctaac gaaaaacaaa gccttggtgg tgccttgtac
    14401 aaacacttga tgagtggtgt atctcaaatg ttaccattcg ttatcggtgg tggtatcatg
    14461 attgcccttg ccttcttgat tgacggtgct ttgggtgttc caaatgaaaa ccttggcaat
    14521 cttggttctt accatgagtt agcttctatg ttcatgaaaa ttggtggagc tgcctttggt
    14581 ttgatgcttc cagtctttgc gggttatgtt gcctactcta ttgctgaaaa accgggtttg
    14641 gtagcaggtt tcgtggctgg tgctattgcc aaagaaggtt ttgcctttgg taaaattcct
    14701 tatgccgcag gtggtgaagc aacttcaact cttgcaggtg tctcatctgg tttcctaggt
    14761 gcccttgttg gtggatttat cgcaggtgcc ttggttcttg ccatcaagaa atacgttaaa
    14821 gttcctcgtt cactcgaagg tgctaaatca atccttctat tgccacttct tggaacaatc
    14881 ttgacaggat ttgttatgct agctgtgaat atcccaatgg ctgcaatcaa cactgctatg
    14941 aatgacttcc taggcggtct tggaggaggt tcagctgtcc ttcttggtat cgtccttggt
    15001 ggaatgatgg ctgttgacat gggtggacca gttaataaag cagcttatgt ctttggtaca
    15061 ggtacgcttg cagcaactgt ttcttcaggt ggttctgtag ccatggcagc agttatggct
    15121 ggaggaatgg tgccaccact tgcaatcttt gtcgcaactc ttcttttcaa agataaattt
    15181 actaaggaag aacgtaactc tggtttgaca aacatcatca tgggcttgtc atttatcact
    15241 gagggagcga ttccatttgg tgccgctgac ccagctcgtg cgattccaag cttcatcctt
    15301 ggttcagcag tagcaggtgg actcgttggt cttactggta tcaaactcat ggcgccacac
    15361 ggaggaatct tcgttatcgc ccttacttca aatgctctcc tttacctcgt ttctgtcttg
    15421 gtaggagcaa tcgtaagtgg tgtggtttat ggttacctac gcaaaccaca agcataaaaa
    15481 atagaaaaat gaaaagattg gaccgtttgg tgcagtcttt ttctcttccc gaaatgcctg
    15541 tgaaatatgg tataatagaa gaatggcaaa caagaataca agtacaacaa gacggagacc
    15601 gtctaaagca gaactggaaa gaaaagaagc gattcaacga atgttgattt cgttaggaat
    15661 tgcgatttta ttgattttcg cagccttcaa attaggggct gcaggtataa ccctttataa
    15721 tttaattcgc ttgctagtgg gtagcctagc ttatctggcg atattcggcc tattaatcta
    15781 tctcttcttt ttcaagtgga tacgaaaaca ggaaggactc ttatctggct ttttcaccat
    15841 atttgctggc ttactcttga tttttgaggc ctacttggtt tggaaatatg gtttggacaa
    15901 gtccgttcta aaagggacca tggctcaggt tgtgacagat ctgactggtt ttcgaacgac
    15961 tagctttgct ggagggggct tgatcggggt cgctctttat attccaacag cctttctctt
    16021 ttcaaatatc ggaacttact ttattggttc tatcttgatt ttagtgggtt ctctcctagt
    16081 cagcccttgg tctgtttacg atattgctga atttttcagt agaggctttg ccaaatggtg
    16141 ggaagggcac gagcgtcgaa aagaggaacg ctttgtcaaa caagaagaaa aagctcgcca
    16201 aaaggctgag aaagaggcta gattagaaca agaagagact gaaaaagcct tactcgattt
    16261 gcctcctgtt gatatggaaa cgggtgaaat tctgacagag gaagctgttc aaaatcttcc
    16321 acctattcca gaagaaaagt gggtggaacc agaaatcatc ctgcctcaag ctgaacttaa
    16381 attccctgaa caggaagatg actcagatga cgaagatgtt caggtcgatt tttcagccaa
    16441 agaagccctt gaatacaaac ttccaagctt acaactcttt gcaccagata aaccaaaaga
    16501 tcagtctaaa gagaagaaaa ttgtcagaga aaatatcaaa atcttagaag caacctttgc
    16561 tagctttggt attaaggtaa cagttgaacg ggccgaaatt gggccatcag tgaccaagta
    16621 tgaagtcaag ccggctgttg gtgtaagggt caaccgcatt tccaatctat cagatgacct
    16681 cgctctagcc ttggctgcca aagatgtccg gattgaagca ccaatccctg ggaaatccct
    16741 aatcggaatt gaagtgccca actccgatat tgccactgta tctttccgag aactatggga
    16801 acaatcgcaa acgaaagcag aaaatttctt ggaaattcct ttagggaagg ctgttaatgg
    16861 aaccgcaaga gcttttgacc tttctaaaat gccccacttg ctagttgcag gttcaacggg
    16921 ttcagggaag tcagtagcag ttaacggcat tattgctagc attctcatga aggcgagacc
    16981 agatcaagtt aaatttatga tggtcgatcc caagatggtt gagttatctg tttacaatga
    17041 tattccccac ctcttgattc cagtcgtgac caatccacgc aaagccagca aggctctgca
    17101 aaaggttgtg gatgaaatgg aaaaccgtta tgaactcttt gccaaggtgg gagttcggaa
    17161 tattgcaggt tttaatgcca aggtagaaga gttcaattcc cagtctgagt acaagcaaat
    17221 tccgctacca ttcattgtcg tgattgtgga tgagttggct gacctcatga tggtggccag
    17281 caaggaagtg gaagatgcta tcatccgtct tgggcagaag gcgcgtgctg caggtatcca
    17341 catgattctt gcaactcagc gtccatctgt tgatgtcatc tctggtttga ttaaggccaa
    17401 tgttccatct cgtgtagcat ttgcggtttc atcaggaaca gactcccgta cgattttgga
    17461 tgaaaatgga gcagaaaaac ttcttggtcg aggagacatg ctctttaaac cgattgatga
    17521 aaatcatcca gttcgtctcc aaggctcctt tatctcggat gacgatgttg agcgcattgt
    17581 gaacttcatc aagactcagg cagatgcaga ctacgatgag agttttgatc caggtgaggt
    17641 ttctgaaaat gaaggagaat tttcggatgg agatgctggt ggtgatccgc tttttgaaga
    17701 agctaagtct ttggttatcg aaacacagaa agccagtgcg tctatgattc agcgtcgttt
    17761 atcagttgga tttaaccgtg cgacccgtct catggaagaa ctggagatag caggtgtcat
    17821 cggtccagct gaaggtacca aacctcgaaa agtgttacaa caataaaaaa atagcttctt
    17881 tccaagtttg gagggaagct attttagtgg ctattgattg cttttatttt ctgaagttgg
    17941 cgcattggac tgtttttcgt tttcagtagc aggtttactt gaagcaggag tagaagagtc
    18001 ctgagttgct gttttctgat cttctttttt ctcttccttg acgctagatt ttggtgtttc
    18061 ctcttgctgt gttttttctt gactagtgtt agtctcttta gttggactgg tgttttcctt
    18121 aggggattcc ttttggattt ctttgacaat ggttgtcgtc tggcttgtcg taggttcttt
    18181 tttaatattt ttgttattat ccaaggcgtt cataatcgtg atacttgcgg taatcaagcc
    18241 aaggatacta gcgattgtag caacggtttt ttgaaagact gtaaagcctt ttttgatgtg
    18301 ttctgttttt ggttttgaag ttctacgata gttagacata cattctctcc tttgattatg
    18361 atttattata ctctgtttct ttaaaaaaat cttaaaaaaa gagaaatttc cctttcttgt
    18421 cgcaagctcc gtttcatgat acaatagagg aagtgatttt agaaagcgtg agaaacatga
    18481 tttactttga taattcagcg acgaccaagc cttatcctga agcccttgaa acctatatgc
    18541 aggtcgcttc aaaaatttta ggaaacccat ctagtctcca tcgtttggga gaccaagcaa
    18601 cacgaatctt agatgcttct cgccaacaga ttgcagattt aatcggtaag aaaagcgatg
    18661 aaatcttctt tacctcgggt ggaacagaag gggataactg gcttatcaag ggtgtggcct
    18721 ttgaaaaagc tcagtttggc aagcacatca ttgtttcagc cattgaacat ccagcagtca
    18781 aagagtcagc cctctggttg aaaagtcaag gatttgaagt ggattttgct ccagttgata
    18841 agaaaggctt ggtcgatgtt gaggcgttag caggtttgat acggcatgat acaatcctcg
    18901 tttccatcat ggctgtgaac aatgaaatcg gctctatcca acctattgag gctatttcag
    18961 aattcttggc agacaagccg actatttcct tccacgttga tgcggttcag gcgcttgcca
    19021 aaattccgac tgaaaagtat ctgacagaac gggtggattg cgcgactttc tctagtcaca
    19081 agttccacgg ggttcgaggt gttggctttg tctatatcaa atctggcaag aagattacac
    19141 ctcttcttac aggtggtggc caggagcgag attatcgttc gacaactgaa aatgtggcag
    19201 ggattgcagc gacagccaag gccctccgtt tgtctatgga aaagctagat atctttagga
    19261 gcaagactgg gcagatgaag gcagtgattc gccaagctct tctgaactat ccggatattt
    19321 ttgtcttttc agatgaggaa aactttgcac ctcatattct gacttttgga atcaaaggtg
    19381 ttcgaggtga agtcatcgtt cacgcctttg aagactatga tattttcatc tcaacaacct
    19441 cagcttgttc atctaaggca ggaaaaccag ccggtacctt gattgccatg ggagtggaca
    19501 aagataaggc caagtcagct gtgcgtctta gcctagactt ggaaaatgat atgagtcagg
    19561 tcgagcagtt tttgaccaag ttaaaattga tttacaatca aactagaaaa gtaagatagg
    19621 agcattcatg cagtattcag aaattatgat tcgctacgga gagttgtcaa ccaagggtaa
    19681 aaaccgtatg cgtttcatca ataaacttcg taataatatt tcggacgttt tgtctatcta
    19741 tacccaagtt aaggtaacag cagatcgcga ccgtgcccac gcttacctca atggagctga
    19801 ttacacagca gttgcagaat ctctcaaaca agtttttgga attcaaaact tttctcctgt
    19861 ttataaggtt gaaaaatctg tagaagtttt gaagtcttct gtccaagaga ttatgcggga
    19921 catctacaag gaaggtatga cctttaagat ttctagcaag cgtagcgacc acaactttga
    19981 acttgatagt cgtgaactca accaaacact tggaggggct gtattcgaag ccattccaaa
    20041 tgtgcaagtt caaatgaaaa gtcctgacat caatcttcag gtggagattc gtgaagaagc
    20101 agcctatctt tcttatgaaa ccattcgtgg ggctggtggt ttgccagttg gaacttcagg
    20161 taaagggatg ctcatgttgt caggagggat tgactcacct gtagcaggtt atcttgctct
    20221 taagcgtggg gtggatatcg aggcagttca ctttgctagt ccaccatata ctagtcctgg
    20281 tgccctcaag aaagcgcagg acttgacccg taaattgacc aagtttggcg gaaatatcca
    20341 gtttatagag gtgcctttca cagagattca agaggaaatc aaagccaaag cgccagaagc
    20401 ttatttgatg actctaactc gtcgctttat gatgcggatt actgaccgta ttcgtgaggt
    20461 acgaaatggt ttggttatca tcaatgggga aagtctaggt caagtagcca gccaaaccct
    20521 tgaaagtatg aaggctatca atgctgttac caacactccc atcattcgtc ctgtggttac
    20581 catggacaag ttggaaatca ttgacatcgc ccaggaaatc gatacctttg acatttcaat
    20641 ccaaccgttt gaagactgtt gtaccatttt tgcaccagat cgtccaaaaa caaatcctaa
    20701 aattaagaat gcggagcagt acgaagcgcg tatggatgtt gaaggcttgg ttgagcgagc
    20761 agtggctgga atcatgatta ctgaaatcac acctcaagcc gaaaaagatg aagttgatga
    20821 cttgattgac aatctgctct aattcagaaa atccaaaaga atagcgaaaa tcagtaaaaa
    20881 aagttagttt tttctctaaa aacaggtaaa aaactaactt tttttatttt tatgatataa
    20941 tgatataaaa ttttgaatat agagagtttt ctgacaatga atcaatccta cttttatcta
    21001 aaaatgaaag aacacaaact caaggttcct tatacaggta aggagcgccg tgtacgtatt
    21061 cttcttccta aagattatga gaaagataca gaccgttcct atcctgttgt atactttcat
    21121 gacgggcaaa atgtttttaa tagcaaagag tctttcattg gacattcatg gaagattatc
    21181 ccagctatca aacgaaatcc ggatatcagt cgcatgattg tcgttgctat tgacaatgat
    21241 ggtatggggc ggatgaatga gtatgcggct tggaagttcc aagaatctcc tatcccaggg
    21301 cagcagtttg gtggtaaggg tgtggagtat gctgagtttg tcatggaggt ggtcaagcct
    21361 tttatcgatg agacctatcg tacaaaagca gactgccagc atacggctat gattggttcc
    21421 tcactaggag gcaatattac ccagtttatc ggtttggaat accaagacca aattggttgc
    21481 ttgggcgttt tttcatctgc aaactggctc caccaagaag cctttaaccg ctatttcgag
    21541 tgccagaaac tatcgcctga ccagcgcatc ttcatctatg taggaacaga agaagcagat
    21601 gatacagaca agaccttgat ggatggcaat atcaaacaag cctatatcga ctcgtcgctt
    21661 tgctattacc atgatttgat agcaggggga gtacatctgg ataatcttgt gctaaaagtt
    21721 cagtctggtg ccatccatag tgaaatccct tggtcagaaa atctaccaga ttgtctgaga
    21781 ttttttgcag aaaaatggta agttaagaaa ggaaaaaacg aaatgcatat tgaacatctt
    21841 agccactgga gtggtcatct taaccgtgaa atgtacctta accgttatgg acatggtggg
    21901 attccagttg tggtctttgc ttcatcaggt ggtagtcaca acgaatacta tgattttggc
    21961 atgattgatg cctgtgcttc ctttatcgag gaaggccttg tccagttctt taccctatct
    22021 agtttggata gtgagagctg gttggctact tggaaaaatg ctcatgacca agcggaaatg
    22081 caccgtgcct acgaacgtta tgtgattgag gaggccattc ttttatcaag cacaagacag
    22141 gttggtttga tggcatgatg acgacaggtt gctctatggg agcctatcat gcactcaatt
    22201 tcttcctcca gcatccagat gtctttacca aagtgattgc tctcagtggt gtttacgacg
    22261 cacgtttctt tgtcggtgat tactacaacg atgatgctat ttaccaaaac tcgccagtag
    22321 attatatttg gaaccaaaac gacggctggt ttattgaccg ttaccgtcag gcagagattg
    22381 tgctgtgtac ggggcttgga gcctgggaac aagatggttt gccatccttt tacaagctca
    22441 aagaagcctt tgacaagaaa caaattccag cctggtttgc tgaatgggga catgatgtcg
    22501 cccatgactg ggaatggtgg cgtaaacaaa tgccttattt cctcggtaat ctctatttat
    22561 aaaaggagtt acctatgaat taccttgtta tttctcccta ctatccacaa aactttcaac
    22621 agtttaccat cgaactagct aataaaggca tcacagtctt gggaattggt caagagtctt
    22681 acgagcaatt ggatgagccc ttgcgcaata gcttgaccga gtattttcgt gttgataatc
    22741 ttgagaacat agatgaagtc aaacgtgcag ttgcttttct cttttataaa catggtccaa
    22801 ttggccgcat cgagtctcac aatgaatact ggcttgagct agacgcaaca ctcagagaac
    22861 aattcaatgt ttttggtgcc aaaccagagg atctcaaaaa gacgaaatat aagtctgaaa
    22921 tgaagaaact tttcaaaaaa gcaggtgttc ctgtggtacc tggagctgtt atcaagacgg
    22981 aagcagatgt tgatcaagca gtgaaagaaa tcggtcttcc aatgattgcc aaacctgata
    23041 atggagtggg agcagccgca acctttaaac ttgagacaga agacgatatc aatcacttca
    23101 agcaagaatg ggaccattca accctttatt tctttgaaaa atttgtcact tccagcgaaa
    23161 tctgtacctt tgacgggctc gtggacaagg atggaaagat tgtcttctca acaacctttg
    23221 actacgccta tacaccgctt gacctcatga tttataagat ggacaattct tattatgtgc
    23281 tcaaggatat ggatcctaaa ctgcgcaagt atggggaagc aattgtcaaa gaatttggta
    23341 tgaaagaacg gtttttccat attgagttct tccgtgaggg ggacgattat attaccatcg
    23401 agtacaataa ccgccctgca ggtggtttta ccattgatgt ttataacttt gctcattcct
    23461 tggaccttta tcgtggctat gcagctattg tcgcaggaga ggagttcccg gcgtcagact
    23521 ttgaaactca gtattgtttg gctacttctc gccgtgcaaa tgctcactat gtttattcag
    23581 aagaggattt gcttgccaaa tatagccagc agttcaaggt taaaaaagtc atgccagctg
    23641 ccttcgcgga acttcaagga gattacctgt atatgctgac cactccgagt cgacaagaaa
    23701 tggagcagat gattgcagat ttcggacaac gtcaagaata agaactatcg gattaaggaa
    23761 attaactccc ttaatccttt tgttttgtct gataaaaaat aagagcatcc caacaaggta
    23821 gctatcataa aacttgttcg ataactattt gaagcaggat taggtggtca gaaattaaat
    23881 tttaatattt caattgagtc atagtattgt gtttgcgtat ccttaaatca gctaaaagga
    23941 tccatgacga cacctatacg atatagtttt caagatacca aacaagtcta ttaatattca
    24001 atgaaaatca aagagcaaac taggaagcta gccgcaggtt tctcaaaaca ctgttttgag
    24061 gttgtggata gaactgacag agtcagtatc atatacctac ggcaaggtga agctgacgtg
    24121 gtttgaagag attttcgaag agtataaaat attcaggtga cgcatagata tagttaattg
    24181 aagctttgtt tgaaatctga taaaataatg atattactaa gttttaaaaa ctaaagaaaa
    24241 gggaagatat gattacaggc gaattaaaaa ataaaatcga tcagctgtgg gaaattcttt
    24301 ggacagaagg aaacgcaaat cctttaacaa atattgaaca gttgacttat ctcttattta
    24361 tgaaagattt ggatagtgtc gagcttggac gtgaaagtga tgctgaattt ctagggattc
    24421 cttatgaggg agtttttcca aaagataaac ctgaataccg ttggtcaact tttaaaaata
    24481 taggagatgc tcaggaagtt tatcgtttaa tgactcagga gatttttccg tttattaaaa
    24541 atctcaaggg ggatacagat gatacagcct tttcacgata tatgcgagaa gctatttttc
    24601 aaataaataa acctgctacg cttcaaaagg caatttctat cttagatgtt tttccaacta
    24661 ggggattaga tgtagatttt gataatgaca aacaaagtat tactgatatc ggagatatct
    24721 atgaatatct gttatcaaaa ttgtcgaccg caggtaaaaa tggacagttc cgtacacctc
    24781 gtcacatcat cgatatgatg gttgagttga tgcaaccgac tatcaaagat atcatctcag
    24841 atcccgctat gggttctgct ggcttcttag tatctgctag ccgttactta aagcgtaaga
    24901 aagatgaatg ggaaaccaat acagataata tcaatcattt tcataatcag atgtttcatg
    24961 gaaatgatac ggatacgact atgttgagac ttggggcgat gaacatgatg ctacatggag
    25021 tagaaaatcc acaaatcagt taccttgact cgctgtctca agataatgaa gaagccgata
    25081 aatatacttt ggttttagca aatcctcctt ttaagggctc acttgactac aattcaacct
    25141 ctaatgacct tcttgcaacc gtaaaaacca aaaaaacaga attactcttt ctttctcttt
    25201 tcttgcgaac tttaaaacca ggtggacgag cagcagttat cgtacctgat ggtgtccttt
    25261 ttggttcgtc taaagctcat aaaggaattc gtcaggaaat tgtagagaat cataagcttg
    25321 atgctgtaat ctcaatgcct agtggtgtgt tcaagcctta tgctggagtt tcaactgcca
    25381 ttctcatctt tacaaaaact ggtaatggtg gtactgacaa agtctggttt tacgatatga
    25441 aagcggatgg tttaagtttg gatgataagc gacaaccgat tagcgacaat gatattccag
    25501 atattatcga acgctttcat catcttgaaa aagaagcaga acgtcagaga acggatcaat
    25561 ctttctttgt tccagttgct gagataaagg aaaatgatta tgatttgtct atcaataaat
    25621 ataaagagat tgagtatgaa aaagttgagt atgaaccaac agaagtcata ttaaagaaaa
    25681 tcaatgattt agaaaaagaa attcaagctg gcttggctga attggaaaaa ttactcaagt
    25741 agggaggtgg ctgtatgaaa aaagtgaagt tgggggaagt cttatctcta aaaaaaggca
    25801 agaaagccac tgtacttgct gaacaaacaa ctctaagcca acgttatatt caaatagatg
    25861 atttaagaaa taataataat ttaaaattca ctgaaagttt aaatatgact gaagcactcc
    25921 cagatgatat tctgatagca tgggatggag ctaatgcagg aacagttggt tatggattat
    25981 cgggagctgt tggtagtaca attacggtct taaaaaagaa tgagcgatac aaagaaaaaa
    26041 ttatatcaga ttacttggga gtctttttgg aaagtaaatc gcagtattta cgagatcatt
    26101 caacaggtgc aacaattcct catttaaaca agaatatatt acttgattta caattagaat
    26161 tgctaggtat cgaagaacaa gagaacatta tctgtattct taatacgatt aaaaggctta
    26221 ttactaaaag aaaatttcag ttagatgaac taaacttgct cg
//
LOCUS       DAVFER010000026        24947 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1105170250
            SAMEA2167659-rid19724873.denovo.026, whole genome shotgun sequence.
ACCESSION   DAVFER010000026 DAVFER010000000
VERSION     DAVFER010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2167659
            Sequence Read Archive: ERR388902
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 24947)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24947)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928716.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928716.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 04:07:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,118
            CDSs (total)                      :: 2,073
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 120
            CDSs (without protein)            :: 120
            Pseudo Genes (ambiguous residues) :: 0 of 120
            Pseudo Genes (frameshifted)       :: 67 of 120
            Pseudo Genes (incomplete)         :: 47 of 120
            Pseudo Genes (internal stop)      :: 34 of 120
            Pseudo Genes (multiple problems)  :: 23 of 120
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24947
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2167659-rid19724873.denovo.026"
                     /strain="1105170250"
                     /db_xref="taxon:1313"
     gene            complement(<1..326)
                     /locus_tag="VU534_001224"
     CDS             complement(<1..326)
                     /locus_tag="VU534_001224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU1513815.1"
                     /translation="MEQLHFITKLLDIKDPNIKILDIINMDTHKEIIAKLDYEAPSCP
                     DCGSLMKKHDFQKPSKIPYLETTGMPSRILLRKRRFKCYHSSKMMVAETPLVKKNHQI
                     PRIINQ"
     gene            complement(466..990)
                     /locus_tag="VU534_001225"
     CDS             complement(466..990)
                     /locus_tag="VU534_001225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000684222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topology modulation protein"
                     /protein_id="HEU1513816.1"
                     /translation="MKIAIIGYSGSGKSTIAEKLSNYYSIPKLHMDTLQFQPGWQDSD
                     CEWMLTEIKNFLTKHKAWVIDGNYSWCYYQERMQEADQIIFLNFSPLTCLFRAFKRYL
                     KYRGKVRESMAVDCPERFEWEFIRWILWDGRSKTQKENYQKLCQEYSHKVTILRNQRE
                     LDQFLDKKRKSYNS"
     gene            complement(1043..1279)
                     /locus_tag="VU534_001226"
     CDS             complement(1043..1279)
                     /locus_tag="VU534_001226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001274003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HEU1513817.1"
                     /translation="MANIKSAIKRAELNVKQNEKNSAQKSAMRTAIKAFEANPSEELF
                     RAASSAIDKAETKGLIHKNKASRDKARLSAKLVK"
     gene            complement(1347..2267)
                     /locus_tag="VU534_001227"
     CDS             complement(1347..2267)
                     /locus_tag="VU534_001227"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HEU1513818.1"
                     /translation="MTNEFLHFEKISRQTWQSLHRKTTPPLTEEELESIKSFNDQISL
                     QDVTDIYLPLAHLIQIYKRTKEDLAFSKGIFLQRESKSQPFIIGVSGSVAVGKSTTSR
                     LLQILLSRTFTDATVELVTTDGFLYPNQTLIEQGILNRKGFPESYDMEALLNFLDRIK
                     NGQDVDIPVYSHEVYDIVPEEKQSVKAADFVIVEGINVFQNPQNDRLYITDFFDFSIY
                     VDAGVDDIESWYLDRFLKMLSLAQNDPDSYYYRFTQMPIGEVESFAHQVWISINLTNL
                     QNYIEPTRNRAEVILHKSKNHEIDEIYLKK"
     gene            2457..2860
                     /locus_tag="VU534_001228"
                     /pseudo
     CDS             2457..2860
                     /locus_tag="VU534_001228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698118.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            3076..3657
                     /locus_tag="VU534_001229"
     CDS             3076..3657
                     /locus_tag="VU534_001229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000289981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEU1513819.1"
                     /translation="MYYAENPDAAHDIHELRVDLLGEKMTFLTDAGVFSKKMVDFGSQ
                     LLLKCLDVNQGETVLDVGCGYGPLGLSLVKVYGVQATMVDINTRALDLAQRNAEKNNA
                     KATIFQSNIYARVQGRFDHVISNPPIRAGKQVVHEIIEKSKDFLEIGGDLTIVIQKKQ
                     GAPSAKSKMEDVFGNCEILKKDKGYYILRSVKE"
     gene            3654..4931
                     /locus_tag="VU534_001230"
     CDS             3654..4931
                     /locus_tag="VU534_001230"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001202959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HEU1513820.1"
                     /translation="MRAVDLIQKKRDGQELTSSEIEWLIEGYVSGTVPDYQMSAFAMA
                     VYFKGMTTREISDLTMNMVKTGQEFDLSAIDGVKVDKHSTGGVGDKVTLILAPLVASF
                     GVPVAKMSGRGLGHTGGTIDKLESIKGYQVERSQEDFIRQVQDIGVSVIGQSDQLVKA
                     DKLLYALRDVTATVDTIPLIASSVMSKKIAAGADAILLDVTVGEGAFMKTVDEARELA
                     QTMVDLGKVVGRKTVAVITDMSQPLGRAIGNRLEILEALEILQGQGRQDITHFICELA
                     QIMLGLANVNKTVEEVHQHLENGQALAKFEEMVQAQGGDLEDLYRPVNVAHVVEIPAQ
                     ETGVISALPAMDFGLYAMRLGAGRAVKSDALDYETGIVFEKKIGDSVQKGEIVAKVYT
                     NEKIPPQLVTDFQKCVKISDEVKKIREIVEIIS"
     gene            4949..5611
                     /gene="deoC"
                     /locus_tag="VU534_001231"
     CDS             4949..5611
                     /gene="deoC"
                     /locus_tag="VU534_001231"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000773666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HEU1513821.1"
                     /translation="MKLNKYIDHTLLKQDAKKKQIDSLLSEAREYDFASVCVNPTWVE
                     HAKKGLEGTDVKVCTVVGFPLGATTSAVKAFETKEAIQNGADEIDMVINVGALKSGNL
                     ALVESDIRAVVEASGDKLVKVIIEACLLTDQEKVVVCQLAQKAGADFVKTSTGFSTGG
                     ATIADVTLMRETVGSDMGVKAAGGARSYADALAFVEAGATRIGTSAGVAILKGELADG
                     DY"
     gene            5598..5987
                     /locus_tag="VU534_001232"
     CDS             5598..5987
                     /locus_tag="VU534_001232"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HEU1513822.1"
                     /translation="MATTELIELAIETSKHAYVPYSHFPIGAVLVAKDGSVYTGVNIE
                     NASYPLTNCGERTAIFKAISEGQREFSELIVYGQTEKPISPCGACRQVMAEFFEQDLK
                     VTLVAKDKSTVEMTVGELLPYSFTDLN"
     gene            6077..7129
                     /locus_tag="VU534_001233"
     CDS             6077..7129
                     /locus_tag="VU534_001233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family protein"
                     /protein_id="HEU1513823.1"
                     /translation="MNKKQWLGLGLVAVAAVGLAACGNRSSRNAASSSDVKTKAAIVT
                     DTGGVDDKSFNQSAWEGLQAWGKEHNLSKDNGFTYFQSTSEADYANNLQQAAGSYNLI
                     FGVGFALNNAVKDAAKEHTDLNYVLIDDVIKDQKNVASVTFADNESGYLAGVAAAKTT
                     KTKQVGFVGGIESEVISRFEAGFKAGVASVDPSIKVQVDYAGSFGDAAKGKTIAAAQY
                     AAGADIVYQVAGGTGAGVFAEAKSLNESRPENEKVWVIGVDRDQEAEGKYTSKDGKES
                     NFVLVSTLKQVGTTVKDISNKAERGEFPGGQVIVYSLKDKGVDLAVTNLSEEGKKAVE
                     DAKAKILDGSVKVPEK"
     gene            7273..8808
                     /locus_tag="VU534_001234"
     CDS             7273..8808
                     /locus_tag="VU534_001234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000929819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU1513824.1"
                     /translation="MAHENVIEMRDITKVFGGFVANDKINLHLRKGEIHALLGENGAG
                     KSTLMNMLAGLLEPTSGEIAVNGQVVNLDSPSKAASLGIGMVHQHFMLVEAFTVAENI
                     ILGSELTKNGVLDIAGASKEIKALSERYGLAVDPSAKVADISVGAQQRVEILKTLYRG
                     ADILIFDEPTAVLTPSEIDELMAIMKNLVKEGKSIILITHKLDEIRAVSDRVTVIRRG
                     KSIETVEIAGATNADLAEMMVGRSVSFKTEKQASKPKEVVLSIKDLVVNENRGVPAVK
                     NLSLDVRAGEIVGIAGIDGNGQSELIQAITGLRKVESGSIELKGDSIVGLHPRQITEL
                     SVGHVPEDRHRDGLILEMMISENIALQTYYKEPHSKNGILNYSNITSYAKKLMEEFDV
                     RAASELVPAAALSGGNQQKAIIAREIDRDPDLLIVSQPTRGLDVGAIEYIHKRLIEER
                     DNGKAVLVVSFELDEILNVSDRIAVIHDGKIQGIVSPETTNKQELGVLMAGGNLGKEK
                     SDV"
     gene            8801..9859
                     /locus_tag="VU534_001235"
     CDS             8801..9859
                     /locus_tag="VU534_001235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU1513825.1"
                     /translation="MSKKLQQISVPLISVFLGILLGAIVMWIFGYDAIWGYEELFYTA
                     FGSLRGIGEIFRAMGPLVLIGLGFAVASRAGFFNVGLPGQALAGWILSGWFALSHPDM
                     PRPLMILATIVIALIAGGIVGAIPGILRAYLGTSEVIVTIMMNYIVLYVGNAFIHAFP
                     KDFMQSTDSTIRVGANATYQTPWLAELTGNSRMNIGIFFAIIAVAVIWFMLKKTTLGF
                     EIRAVGLNPHASEYAGISAKRTIILSMIISGALAGLGGAVEGLGTFQNVYVQGSSLAI
                     GFNGMAVSLLAANSPIGILFAAFLFGVLQVGAPGMNAAQVPSELVSIVTASIIFFVSV
                     HYLIERFVKPKKQVKGGK"
     gene            9862..10818
                     /locus_tag="VU534_001236"
     CDS             9862..10818
                     /locus_tag="VU534_001236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU1513826.1"
                     /translation="MSIITLLPLLVSSMLIYSAPLIFTSIGGVFSERGGVVNVGLEGI
                     MVMGAFSGVVFNLEFAEQFGAATPWLSLLVAGLVGSVFSIIHAAATVHFRADHVVSGT
                     VLNLMAPALAVFLVKVLYNKGQTDNLSQTFGRFDFPVLANIPVIGDIFFKSTSLLGYL
                     AIAFSFLAWFILFKTQFGLRLRSVGEHPQAADTLGINVYKMRYLGVIISGFLGGIGGA
                     IYAQSISVNFSVTTIVGPGFIALAAMIFGKWNPIGAMLSSLFFGLSQSLAVIGSQLPF
                     LQGVPAVYLQIAPYVLTILVLAAFFGKAVAPKADGINYIKSK"
     gene            10903..12174
                     /locus_tag="VU534_001237"
                     /pseudo
     CDS             10903..12174
                     /locus_tag="VU534_001237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(12217..12858)
                     /gene="plsY"
                     /locus_tag="VU534_001238"
     CDS             complement(12217..12858)
                     /gene="plsY"
                     /locus_tag="VU534_001238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HEU1513827.1"
                     /translation="MITIVLLILAYLLGSIPSGLWIGQVFFQINLREHGSGNTGTTNT
                     FRILGKKAGMATFVIDFFKGTLATLLPIIFHLQGVSPLIFGLLAVIGHTFPIFAGFKG
                     GKAVATSAGVIFGFAPIFCLYLAIIFFGALYLGSMISLSSVTASIAAVIGVLLFPLFG
                     FILSNYDSLFIAIILALASLIIIRHKDNIARIKNKTENLVPWGLNLTHQDPKK"
     gene            12994..14937
                     /gene="parE"
                     /locus_tag="VU534_001239"
     CDS             12994..14937
                     /gene="parE"
                     /locus_tag="VU534_001239"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HEU1513828.1"
                     /translation="MSKKEININNYNDDAIQVLEGLDAVRKRPGMYIGSTDGAGLHHL
                     VWEIVDNAVDEALSGFGDRIDVTINKDGSLTVQDHGRGMPTGMHAMGIPTVEVIFTIL
                     HAGGKFGQGGYKTSGGLHGVGSSVVNALSSWLEVEITRDGAVYKQRFENGGKPVTTLK
                     KIGTAPKSKTGTKVTFMPDATIFSTTDFKYNTISERLNESAFLLKNVTLSLTDKRTNE
                     AIEFHYENGVQDFVSYLNEDKEILTPVLYFEGEDNGFQVEVALQYNDGFSDNILSFVN
                     NVRTKDGGTHETGLKSAITKVMNDYARKTGLLKEKDKNLEGSDYREGLAAVLSILVPE
                     EHLQFEGQTKDKLGSPLARPVVDGIVADKLTFFLMENGELASNLIRKAIKARDAREAA
                     RKARDESRNGKKNKKDKGLLSGKLTPAQSKNPAKNELYLVEGDSAGGSAKQGRDRKFQ
                     AILPLRGKVVNTAKAKMADILKNEEINTMIYTIGAGVGADFSIEDANYDKIIIMTDAD
                     TDGAHIQTLLLTFFYRYMRPLVEAGHVYIALPPLYKMSKGKGKKEEVAYAWTDGELEE
                     LRKQFGKGATLQRYKGLGEMNADQLWETTMNPETRTLIRVTIEDLARAERRVNVLMGD
                     KVEPRRKWIEDNVKFTLEETTVF"
     gene            15357..17828
                     /gene="parC"
                     /locus_tag="VU534_001240"
     CDS             15357..17828
                     /gene="parC"
                     /locus_tag="VU534_001240"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HEU1513829.1"
                     /translation="MSNIQNMSLEDIMGERFGRYSKYIIQDRALPDIRDGLKPVQRRI
                     LYSMNKDSNTFDKSYRKSAKSVGNIMGNFHPHGDSSIYDAMVRMSQNWKNREILVEMH
                     GNNGSMDGDPPAAMRYTEARLSEIAGYLLQDIEKKTVPFAWNFDDTEKEPTVLPAAFP
                     NLLVNGSTGISAGYATDIPPHNLAEVIDAAVYMIDHPTAKIDKLMEFLPGPDFPTGAI
                     IQGRDEIKKAYETGKGRVVVRSKTEIEKLKGGKEQIVIIEIPYEINKANLVKKIDDVR
                     VNNKVAGIAEVRDESDRDGLRIAIELKKDANTELVLNYLFKYTDLQINYNFNMVAIDN
                     FTPRQVGIVPILSSYIAHRREVILARSRFDKEKAEKRLHIVEGLIRVISILDEVIALI
                     RASENKADAKENLKVSYDFTEEQAEAIVTLQLYRLTNTDVVVLQEEEAELREKIAMLA
                     AIIGDERTMYNLMKKELREVKKKFATPRLSSLEDTAKAIEIDTASLIAEEDTYVSVTK
                     AGYIKRTSPRSFAASTLEEIGKRDDDRLIFVQSAKTTQHLLMFTSLGNVIYRPIHELA
                     DIRWKDIGEHLSQTITNFETNEEILYVEVLDQFDDATTYFAVTRLGQIKRVERKEFTP
                     WRTYRSKSVKYAKLKDDTDQIVAVAPIKLDDVVLVSQNGYALRFNIEEVPVVGAKAAG
                     VKAMNLKEDDVLQSGFICNTSSFYLLTQRGSLKRVSIEEILATSRAKRGLQVLRELKN
                     KPHRVFLAGAVAEQGFVGDFFSTEVDVNDQTLLVQSNKGTIYESRLQDLNLSERTSNG
                     SFISDTISDEEVFDAYLQEVVTEDK"
     gene            17960..18982
                     /locus_tag="VU534_001241"
     CDS             17960..18982
                     /locus_tag="VU534_001241"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HEU1513830.1"
                     /translation="MTVTIDWENLGFSYMKLPYRYLAHFKNGQWDQGELTEDATLHIS
                     ESSPSLHYGQQAFEGLKAYRTKDGSVQLFRPDENAKRLQRTCDRLLMPQVPTDMFVEA
                     CKAVVRANEEYVPPYGTGGTLYLRPLLIGVGDIIGVKPAEEYIFTIFAMPVGNYFKGG
                     LVPTNFLIQDEYDRAAPNGTGAAKVGGNYAASLLPGKMAKSRHFSDVIYLDPSTHTKI
                     EEVGSANFFGITADNEFVTPLSPSILPSITKYSLLYLAEHRLGLTPIEGDVPIDNLDR
                     FVEAGACGTAAVISPIGGIQHGDDFHVFYSETEVGPVTRKLYNELTGIQFGDIEAPEG
                     WIVKVD"
     gene            19038..19742
                     /locus_tag="VU534_001242"
     CDS             19038..19742
                     /locus_tag="VU534_001242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEU1513831.1"
                     /translation="MVLSTSAILVACGKTDKEADAPTTFSYVYAVDPASLGYSIATRT
                     SRTDVIGNVIDGLMENDKYGNVAPSQKDYDLNSTGWAPSYQDPASHLNIIDPKSGSAM
                     KHLGITKGKDKDVVAKPGLDKYKKLLEDAVSETTDLEKRYEKYAKAQAWSTDSSLLMP
                     TASSGGSPVVSNVVPFSKPYSQVGIKGDPYIFKGMKLQKDIVTTKEYNEVFKKWQKEK
                     LESNSKYQKELEKHIK"
     gene            19807..20496
                     /locus_tag="VU534_001243"
     CDS             19807..20496
                     /locus_tag="VU534_001243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000454813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HEU1513832.1"
                     /translation="MEWIRLIGIAIIVVGFILKFDTIATVVLAGLVTALVSGVSLVEF
                     LEILGKEFSNQRVLTIFMVTLPLVGLSETFGLKQRSIDLIRKIKGLTVGNFYTVYFFI
                     RELAGFFSIRLGGHPQFVRPLVQPMGEAAAESQLGRKLTEVEDETIKARAAANENFGN
                     FFAQNTFVGAGGVLLIGGTLDQLGYESNYAGIASTSIIVAVITLIVVGIYNYLFDKKL
                     ISKKTRGGEQK"
     gene            20493..21416
                     /locus_tag="VU534_001244"
     CDS             20493..21416
                     /locus_tag="VU534_001244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HEU1513833.1"
                     /translation="MTELAKQLLELTYIVIGCQFLHTAYCSYKDKTNPVRLGTSAFWT
                     LLSITFIGGSYMPNMSIGIIVILLSLLTLFKQVRIGTLPSLDEMKANIESNRLKNKIF
                     IPVMLMAILALVLAQMIPEFSKISISLAALFATISVLVITNSHPKSLLSENNRMTQQV
                     STSGIVPQLLGALGAIFTVAGVGDVISHLISGIVPSDSRFIGVLAYVLGMVLFTMIMG
                     NAFAAFTVITAGVGVPFVFALGANPIVAGALAMTAGYCGTLLTPMAANFNALPAALMD
                     MKDQNGVIKAQAGVALVMIVIHIFLMYFLAF"
     gene            21431..22075
                     /gene="pcp"
                     /locus_tag="VU534_001245"
     CDS             21431..22075
                     /gene="pcp"
                     /locus_tag="VU534_001245"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HEU1513834.1"
                     /translation="MKILVTGFNPFGGEKINPALEAVKLLPSEINGAEVRWVEIPTVF
                     YKSSEVLEAEILRYQPDAVLCIGQAGGRTGLTPERVAINQDDARIPDNEGNQPIDTPI
                     RIDGASAYFSSLPIKAMVQAIKKQGLPAVVSNSAGTFVCNHLMYQALYLVDKKFPNMR
                     AGFMHIPYMMEQVINKPNTAGMSLCDIVRGIEVAIEAIVDYKDKDLQLVGGETH"
     gene            22243..22473
                     /locus_tag="VU534_001246"
     CDS             22243..22473
                     /locus_tag="VU534_001246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000037109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2969 domain-containing protein"
                     /protein_id="HEU1513835.1"
                     /translation="MSKKDKKIEIQVADAKVNVGKDSFEGYTLTIGKKVIGEIAELDG
                     QFAIIKNGNVDSFYKKLEKAVEILIENYNLAK"
     gene            22523..22603
                     /locus_tag="VU534_001247"
     tRNA            22523..22603
                     /locus_tag="VU534_001247"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:22557..22559,aa:Tyr,seq:gta)
     gene            22613..22684
                     /locus_tag="VU534_001248"
     tRNA            22613..22684
                     /locus_tag="VU534_001248"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:22645..22647,aa:Gln,seq:ttg)
     gene            22846..24048
                     /gene="rpsA"
                     /locus_tag="VU534_001249"
     CDS             22846..24048
                     /gene="rpsA"
                     /locus_tag="VU534_001249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HEU1513836.1"
                     /translation="MNEFEDLLNSVSQVETGDVVSAEVLTVDATQANVAISGTGVEGV
                     LTLRELTNDRDADINDFVKVGEVLDVLVLRQVVGKDTDTVTYLVSKKRLEARKAWDKL
                     VGREEEVVTVKGTRAVKGGLSVEFEGVRGFIPASMLDTRFVRNAERFVGQEFDTKIKE
                     VNAKENRFILSRREVVEAATAAARAEVFGKLAVGDVVTGKVARITSFGAFVDLGGVDG
                     LVHLTELSHERNVSPKSVVTVGEEIEVKILDLNEEEGRVSLSLKATVPGPWDGVEQKL
                     AKGDVVEGTVKRLTDFGAFVEVLPGIDGLVHVSQISHKRIENPKEALKVGQEVQVKVL
                     EVNADAERVSLSIKALEERPAQEEGQKEEKRAARPRRPRRQEKRDFELPETQTGFSMA
                     DLFGDIEL"
     gene            complement(24134..24947)
                     /locus_tag="VU534_001250"
                     /pseudo
     CDS             complement(24134..24947)
                     /locus_tag="VU534_001250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
BASE COUNT         7527 a         4384 c         5618 g         7418 t
ORIGIN      
        1 ttttggttga tgatacgagg gatttggtga tttttcttta ccaggggagt ctcagcaacc
       61 atcatttttg aagagtgata gcacttgaaa cggcgttttc taaggagaat tctagaaggc
      121 ataccagttg tttcgaggta agggatctta gacggttttt gaaagtcatg tttcttcatt
      181 agacttccac aatcagggca agatggagcc tcataatcca gcttagcgat aatttctttg
      241 tgggtatcca tattgatgat atctagaatc ttgatgtttg ggtctttaat atcgagcagt
      301 tttgtgataa aatgtaattg ttccatatga ttctttctaa tgagttgttt tgtcgctttt
      361 cattataggt catatgggac tttttttcta cacaaaaata ggctccataa tatctatagt
      421 ggatttaccc actacaaata ttatagagcc caaaaaggaa gccctttatg aattgtagga
      481 cttccttttc ttatccagaa attgatctag ctctctctga tttcgaagaa tagtgacttt
      541 atgtgaatat tcttggcaaa gtttttggta attttctttt tgagttttgc tacgcccatc
      601 ccaaagaatc catctgataa actcccactc aaagcgttca gggcaatcta ccgccatact
      661 ttctctgact tttccacggt atttaagata acgcttaaag gctctaaaga gacaggtcaa
      721 tggcgaaaaa ttgagaaaga tgatttggtc agcttcttgc attcgttctt ggtagtagca
      781 ccaagaataa ttaccatcga tgacccaagc tttatgcttg gtgagaaagt tttttatctc
      841 ggttaacatc cattcgcagt cactgtcttg ccaaccaggt tgaaattgga gtgtgtccat
      901 gtgcagtttt ggaatggagt agtagttaga taacttttct gctatagttg acttaccaga
      961 accagaatat ccgataattg cgattttcat tttctacctt ttcctatttg gagacaaaaa
     1021 aacagcctct atggactgtt tcttatttaa caagtttagc tgaaagacga gctttatcgc
     1081 ggcttgcttt gtttttgtga atcaaacctt tagtttctgc tttatcgata gctgagctag
     1141 cagcacggaa aagttcttca gatgggtttg cttcgaaagc ttttatagca gtacgcatag
     1201 ctgatttttg agctgagttc ttttcgtttt gtttaacgtt caattcagcg cgtttgatag
     1261 ctgatttaat gtttgccaat gttcttacct ccatatttac taactatacc attatatatg
     1321 aaaacttacg ttttgacaag ggaaaattac ttttttaagt aaatttcatc gatttcatgg
     1381 ttcttgcttt tatgaagaat cacttctgca cgatttctgg ttggttcaat ataattttgc
     1441 agatttgtga gattgatact gatccagacc tgatgggcaa aggactccac ttccccaatc
     1501 ggcatctgag taaaacgata atagtagcta tcagggtcgt tttgggctag actcagcatt
     1561 ttcaagaaac ggtccagata ccaactttca atatcatcca ctccagcatc tacatagatg
     1621 gaaaagtcaa agaagtcagt gatatagaga cgatcgtttt gtggattttg aaagacattg
     1681 attccctcaa caattacaaa atcagcagct ttgacacttt gtttctcttc gggtacgatg
     1741 tcgtaaactt catgagaata gacaggaata tctacatctt gtccattttt gatgcggtcc
     1801 aagaagttga gaagagcttc catatcatag ctttcaggaa atcctttacg atttaaaatc
     1861 ccctgctcaa tcaaggtttg attgggatag agaaaaccat cagttgtaac caactcaacc
     1921 gtagcatctg taaacgtacg ggacagtagg atttgaagta ggcgactggt tgtggatttt
     1981 ccaacggcaa cactcccaga aaccccaata ataaaaggtt gagatttact ttcacgttgg
     2041 aggaaaattc cttttgaaaa ggctaaatct tccttagttc gcttgtaaat ctgaatcaaa
     2101 tgagccaagg ggagatagat atctgtaacg tcttggagac tgatttggtc attaaaactc
     2161 ttgatagatt ccaattcttc ttctgtcaaa ggaggtgttg tctttcgatg taaagattgc
     2221 caagtctggc ggctgatttt ttcaaaatgt aaaaattcgt tggtcatttg ttttccccta
     2281 gatattttgt ctatcatacc ataaaaagct aaaaaaataa agcggtttct tgaatgtggt
     2341 aagtcaatgg tatatagtat aagtgatcaa tttattgatg aaataggaga tagattctac
     2401 tgatttataa gcttataaag ggggcttttt agttcacaac ttataggagg tgtactatga
     2461 aaatcttaaa acgttacata ttggaactct gttttatttt aagttttgct ttacctttta
     2521 taaaaggaac caatgcagat aatggtagat gctttgtgga aacctattac ggttttactt
     2581 ttttgatgga acatgctatt gtaacagctg tctttatttg ttcgttctta attgctttct
     2641 tactaaaaaa cgatggacga aatggattgc tgcgggtagt tattgctttt tagtcctacg
     2701 gattgcgaca gagggttatt tcttccacat gtcactagaa gatttgatac gactttggac
     2761 aagtttggaa atcctgacac aaacgtatca gttgggcttt tatctaaaca ttttgttagg
     2821 aattttgttg ataataaagt attttaaggt taagcaatag aaataataat ctgcctgatt
     2881 atagatgata aactttttgt ttttatctgg actgtgatat ttatagttct aaatggttta
     2941 ttatttataa gtgttgaaag agattgaaga aaatggcttc gtgacttgct ttcttcggtc
     3001 tttttcgttt tattatcaat ttgtaaacga tttacaattt gagtcaaatt atggtaaaat
     3061 agtgtcatga gtaaaatgta ctatgcagaa aatcctgacg ctgctcacga cattcatgag
     3121 ttgagagtgg acttgttggg agaaaaaatg acttttttga cagatgcggg tgtttttagc
     3181 aagaaaatgg ttgactttgg aagtcaactc ttgctcaagt gtctggatgt caaccaagga
     3241 gagacagtcc tagatgtagg ctgtggttat ggtccattag gtttgtcctt ggtcaaggtt
     3301 tacggagttc aggcgaccat ggttgatatt aacactcgtg ccctggattt agctcagaga
     3361 aatgctgaaa aaaataatgc aaaagcgacg atatttcaat ctaatattta tgcaagagtt
     3421 caagggcgat ttgaccatgt catttccaat cctcctatcc gtgcgggcaa gcaagtcgtt
     3481 catgaaatca tcgagaaaag taaagatttc ttggaaattg gtggagattt gaccatcgtc
     3541 atccagaaaa aacaaggagc tccaagtgcc aagtctaaga tggaagatgt gtttggcaat
     3601 tgtgaaatcc ttaaaaaaga caagggatac tatatcctta gaagtgtgaa agaatgagag
     3661 cagttgattt aatccaaaaa aaacgagacg gtcaagaact gacttcaagt gaaattgaat
     3721 ggctgataga aggctatgta tcaggaactg ttcctgatta tcagatgtct gcctttgcta
     3781 tggctgttta ttttaaagga atgacgactc gagaaatctc tgatttaacg atgaatatgg
     3841 ttaagactgg gcaagagttt gacctgtcag ccattgatgg tgtgaaagtt gacaagcatt
     3901 ctactggtgg tgtcggcgat aaggtaacct tgattttagc tcctcttgtt gctagcttcg
     3961 gtgtgcctgt agcaaaaatg agtggtcgtg gtcttggcca tacaggcgga acaattgata
     4021 aattggagtc cattaagggc tatcaagtag aacgtagtca agaggatttt attcgtcagg
     4081 ttcaggatat tggagtatct gtcattgggc aatcagacca gctggtcaaa gcagataagc
     4141 ttctctatgc ccttcgtgat gtgaccgcaa ctgtcgacac gattcctttg attgcgagtt
     4201 cggtgatgag caagaaaatt gcggcagggg cggatgctat tttgctagac gtgactgtcg
     4261 gtgagggtgc cttcatgaag acggttgatg aggcgcgtga gttggctcaa actatggtag
     4321 atcttggtaa ggttgttgga cggaagacag tagcagtgat tacggatatg agccagcctt
     4381 tgggacgagc gattggaaat cgtctggaaa tccttgaagc attggagatt ttgcaaggtc
     4441 aaggacgtca ggatattacc cactttattt gtgaattggc tcaaattatg cttggtttgg
     4501 caaatgttaa caaaactgtt gaagaagttc accaacatct tgagaatggt caagcactgg
     4561 ctaagtttga ggaaatggtg caagcccaag gtggagactt ggaagacctc tatcgtcctg
     4621 taaatgtagc tcatgtggtg gaaatccctg ctcaggaaac gggtgtcatt tcagctcttc
     4681 cagctatgga ctttggtctt tatgccatga ggctgggtgc tggtcgtgca gttaagtctg
     4741 atgccttgga ctatgaaaca ggaattgttt ttgaaaagaa gattggagac tccgttcaaa
     4801 agggtgaaat tgttgcaaaa gtatacacaa atgaaaaaat tccacctcaa ctagttacag
     4861 atttccaaaa atgtgttaaa ataagtgatg aagtgaaaaa aatccgtgaa attgtagaaa
     4921 tcatctccta aatggaggga aaaccgaaat gaaattaaat aaatatatag atcatacgct
     4981 tttaaaacaa gatgcaaaga aaaaacaaat tgatagtttg ttgtctgagg ctagagagta
     5041 tgactttgcc agtgtttgcg ttaatccgac ctgggttgaa catgctaaaa aaggacttga
     5101 aggcacagat gttaaggttt gcacagtagt aggtttccct ttgggagcaa caacttcagc
     5161 cgtgaaagca tttgagacaa aagaagctat ccaaaatggt gcagatgaga ttgatatggt
     5221 gatcaatgtt ggagctctca aatcaggtaa tttagccttg gttgagtcag atattcgcgc
     5281 agtagtggaa gcaagtggtg ataagttagt gaaagtcatt attgaagctt gccttctgac
     5341 agaccaagaa aaagttgttg tttgccaatt ggcccaaaaa gctggggctg actttgtcaa
     5401 aacatctact ggcttttcaa ctggtggtgc tacgatagca gatgttacat taatgcgtga
     5461 aacagttgga tctgatatgg gtgtcaaggc cgccggtgga gctcgttctt atgcagatgc
     5521 tcttgccttt gtcgaagcag gtgcgacccg tatcggaacg tcagctgggg tagctatttt
     5581 aaaaggagaa ttggcagatg gcgactactg agttgattga actggcaatt gaaaccagca
     5641 aacatgccta tgtcccctat tctcactttc ctatcggagc agttttagta gctaaagacg
     5701 gaagtgttta cacgggagtg aatattgaaa atgctagcta tcctttgacc aattgcggtg
     5761 agagaacagc tatttttaag gctatatctg aaggccaaag agaattttca gaattgattg
     5821 tctatggtca aactgaaaaa ccgatctcgc catgtggtgc ttgtcgccaa gtgatggctg
     5881 aattttttga acaagatcta aaagtgacct tagtcgcaaa agataaatcg acggtcgaga
     5941 tgacggtcgg ggaattactt ccatactctt ttacagactt aaactagtct gagtcgctct
     6001 ctgagtggca cggtccttgt ggccaaccaa tccatacttg caacatcgtt gcacatctta
     6061 tttaggaggt tcagtaatga acaagaaaca atggctaggt cttggcctag ttgcagtggc
     6121 agcagttgga cttgctgcat gtggtaaccg ctcttctcgt aacgcagctt catcttctga
     6181 tgtgaagaca aaagcagcaa tcgtcactga tactggtggt gttgatgaca aatcattcaa
     6241 ccaatcagct tgggaaggtt tgcaggcttg gggtaaagaa cacaatcttt caaaagataa
     6301 cggtttcact tacttccaat caacaagtga agctgactac gctaacaact tgcaacaagc
     6361 ggctggaagt tacaacctaa tcttcggtgt tggttttgcc cttaataatg cagttaaaga
     6421 tgcagcaaaa gaacacactg acttgaacta tgtcttgatt gatgatgtga ttaaagacca
     6481 aaagaatgtt gcgagcgtaa ctttcgctga taatgagtca ggttaccttg caggtgtggc
     6541 tgcagcaaaa acaactaaga caaaacaagt tggttttgta ggtggtatcg aatctgaagt
     6601 tatctctcgt tttgaagcag gattcaaggc tggtgttgcg tcagtagacc catctatcaa
     6661 agtccaagtt gactacgctg gttcatttgg tgatgcggct aaaggtaaaa caattgcagc
     6721 cgcacaatac gcagccggtg cagatattgt ttaccaagta gctggtggta caggtgcagg
     6781 tgtctttgca gaggcaaaat ctctcaacga aagccgtcct gaaaatgaaa aagtttgggt
     6841 tatcggtgtt gatcgtgacc aagaagcaga aggtaaatac acttctaaag atggcaaaga
     6901 atcaaacttt gttcttgtat ctactttgaa acaagttggt acaactgtaa aagatatttc
     6961 taacaaggca gaaagaggag aattccctgg cggtcaagtg atcgtttact cattgaagga
     7021 taaaggggtt gacttggcag taacaaacct ttcagaagaa ggtaaaaaag ctgtcgaaga
     7081 tgcaaaagct aaaatccttg atggaagcgt aaaagttcct gaaaaataat ggatggaagt
     7141 catttcttag gaagcggcca agggccgctt ttttaagagt tgagacaaag tcattttgtc
     7201 taagtaaagc ttgctactag acaaactagc aagttttatt gaaataaaat aagactctga
     7261 aaggaagagc acatggcaca cgaaaatgtc attgagatgc gtgatattac caaggtgttt
     7321 ggtggatttg ttgccaacga caaaatcaac ttgcacctac gaaaaggtga aattcatgca
     7381 cttttaggag aaaatggggc tggtaagtcc acgctaatga acatgttagc aggccttctt
     7441 gaaccaacta gtggtgaaat cgcggtcaac ggtcaagttg tcaatctcga ctccccatct
     7501 aaagcagcta gcttgggaat cgggatggtt caccagcact ttatgttggt tgaagccttc
     7561 acagtggctg aaaacatcat tttaggtagt gaattgacta aaaatggtgt gctagatatc
     7621 gctggagcta gcaaagaaat caaggctctt tctgaacgtt atggcttagc tgttgaccct
     7681 tctgccaagg tagcagatat ctcagttgga gcccaacaac gtgtagaaat tttaaaaaca
     7741 ctttatcggg gggctgatat ccttatcttt gacgaaccaa cggctgtttt gactccatca
     7801 gaaattgatg agttgatggc tattatgaaa aatcttgtca aagaaggaaa atcaattatc
     7861 ttgattaccc acaaattgga tgaaattcga gcagtttctg accgtgttac agttatccgt
     7921 cgtgggaaat caattgaaac cgttgaaatt gcaggggcta ccaatgctga tttggcggaa
     7981 atgatggtag gacgttctgt ttcctttaaa acagagaagc aagcctctaa accaaaagaa
     8041 gtggttttgt ctatcaaaga tttggtggtc aatgaaaacc gtggtgttcc agctgttaaa
     8101 aatctgtcct tggatgttcg tgctggagag attgttggta ttgcggggat tgatggaaat
     8161 ggtcagtctg aactgattca agccattaca ggtcttcgta aggttgaatc tggtagcatt
     8221 gagctaaaag gagattcaat tgtaggcttg cacccacgtc agattacaga actaagtgtt
     8281 gggcacgttc cagaagaccg tcaccgtgat ggcttgattt tggaaatgat gatatctgaa
     8341 aatattgccc ttcaaaccta ctataaagaa ccacatagta aaaatggaat tttgaattat
     8401 tcaaatatta cttcttatgc taaaaagctg atggaagagt ttgatgttcg cgctgccagt
     8461 gaattagttc ctgcagctgc actctcagga ggaaatcaac aaaaagcaat tattgctcgt
     8521 gaaattgatc gagatcctga tctccttatc gttagccagc caactcgtgg gttggatgtc
     8581 ggtgccattg agtatatcca caaacgcttg attgaagagc gtgataatgg caaggctgtc
     8641 cttgttgtca gctttgaatt ggatgagatt ttaaacgtct cagaccgtat tgccgttatc
     8701 cacgatggta agattcaagg tattgtatca ccagaaacaa ccaataaaca agaacttggt
     8761 gtcttgatgg ctggtggaaa cttgggaaag gagaagagtg atgtctaaaa aattacaaca
     8821 aatttcggtt cccttgattt ctgtattcct aggaatttta ctcggagcca ttgtcatgtg
     8881 gatcttcggt tatgatgcta tttggggcta cgaagaattg ttctatacag cctttggcag
     8941 tctgcgtggg attggagaaa tcttccgtgc tatgggtcct ctggtcttga ttggtcttgg
     9001 ttttgccgtt gccagtcgag ctggtttctt taacgtcgga cttcctggtc aggctttggc
     9061 aggttggatt ctcagtggtt ggtttgccct gtcgcatcca gatatgcccc gtcccttgat
     9121 gattctagca accatcgtga ttgccttgat tgctggtggg attgtcggag cgattccagg
     9181 tattcttagg gcctatctag ggacgtcaga ggttattgta accatcatga tgaactacat
     9241 tgtcttgtat gtagggaatg cctttatcca tgctttccct aaagacttca tgcaaagtac
     9301 agattcgacc attcgtgttg gggctaatgc aacctatcag acaccttggt tggctgagtt
     9361 gactggtaac tcacggatga atattggtat tttctttgcc atcattgccg ttgcagttat
     9421 ttggttcatg ctcaagaaaa caactcttgg ttttgaaatc cgtgcagttg gtcttaatcc
     9481 acatgcttca gaatatgctg gtatttctgc caagcggact attatcctat ctatgattat
     9541 ttcaggtgcc ttggcaggtc ttggtggagc tgttgaaggt ttgggaacct tccagaacgt
     9601 ctatgttcaa ggttcgtcat tagctatcgg atttaacgga atggcggtta gtttgcttgc
     9661 ggccaactca ccaattggta tactctttgc agccttccta tttggcgttc tccaagttgg
     9721 ggctcctggt atgaatgcgg cgcaggtacc atctgagctt gtcagcattg taacagcgtc
     9781 tattatcttc tttgtcagtg ttcattacct tatcgaacgc tttgtcaaac cgaaaaaaca
     9841 agttaaagga ggtaagtaaa gatgtctatt ataaccttgc tccccctctt ggtgtcttct
     9901 atgctgattt actcagcacc tctcatcttt acaagtatcg gtggtgtttt ctctgaacgt
     9961 ggtggtgtgg taaacgttgg ccttgaagga attatggtta tgggtgcctt ttctggagtt
    10021 gtctttaacc ttgaatttgc agaacaattt ggagcagcaa ctccatggct atccttgctt
    10081 gtagcaggat tggttggtag tgttttctct atcatccacg cagcagcgac ggttcatttc
    10141 cgtgcagacc atgttgtcag cggtacggta ttgaacttga tggcgcctgc cttggctgtt
    10201 ttcttagtta aagttcttta taacaaagga caaaccgaca acctaagtca aacttttgga
    10261 cgctttgatt tcccagtctt ggcaaatatc ccagtgattg gtgatatctt cttcaagtca
    10321 actagtctac ttggttatct ggcgattgcc ttctcattcc ttgcttggtt tattctcttt
    10381 aagactcaat ttggtcttcg tctccgctct gtcggtgaac atcctcaagc agcggatacc
    10441 ttgggaatca acgtctacaa gatgagatat ttaggggtta ttatttcagg ttttctaggt
    10501 ggaattggcg gagcgattta tgcgcaatca atctcagtta acttctcagt gacaactatt
    10561 gttggacctg gatttatcgc ccttgctgcg atgatctttg ggaaatggaa tccaatcggt
    10621 gctatgcttt ctagtctctt ctttggactt tcacaaagtt tggctgttat cggttctcaa
    10681 ttgccgttcc tacaaggagt gccagcggtt tatcttcaaa ttgcacctta tgttttgaca
    10741 attcttgtct tagcagcctt ctttggaaaa gcagtcgcac caaaagcaga tggtatcaac
    10801 tacatcaaat caaaataagc atacaaaaaa acgtcagtcc aatgactgaa ctacacccca
    10861 aaagttagac agaaaaaatc taacttttgg ggtgttttta ttatgaaatt aagttatgat
    10921 gataaagttc agatctatga acttagaaaa caaggatata gcttagagaa gctttcaaat
    10981 aaatttggga taaacaattc taatcttagg tatatgatta aattgattga tcgttacgga
    11041 atagagttcg tcaaaaaagg aaaaaatcgt tactattctc ctgatttaaa acaagaaatg
    11101 attaataaag tctgacatga aggctggact aaagatagag tttctcttga atacggtctc
    11161 ccaagtcgta cgatacttct taactggcta gcacaataca ggaaaaacgg gtatactatt
    11221 gttgagaaac caagagggag agtacctgag agcggagaat gccatcctaa aaaagttaag
    11281 agaactccga ttgaaggagg aaaaagagaa agaagaaaga cagaaattgt ttaagaatta
    11341 atgactgagt tttcgttaga tcttctttta aaagtcatta aactagctcg ttcgacctac
    11401 tactatcact tgaaacagct agataaacca gataaggacc aagagcttaa agctgaaatt
    11461 caatccattt ttatcgaaca caaaggaaat tatgcttatc gtcggattta tttagaacta
    11521 agaaatcgtg gttatctggt aaatcataaa agagttcaag gcttgatgaa agtactcaat
    11581 ttacaagcta aaacgcgaca gaaacgaaaa tattcttctc ataaaggaga cgttggcaag
    11641 aaggcagaga atctcattca aggccaattt gaaggctcta aaacaatgga acagtgctac
    11701 acagatgtga cagaatttgc cattccagta agtacttaaa agctttactt atcaccagtt
    11761 ttagatggct ttaatagcga aattatcgcc tataatcttt caacttcacc caacttagaa
    11821 caagtacaaa caatgttgga acaggcattc acagagaagc actacgagaa tacgattctc
    11881 catagtgacc aaggctggca ataccaacac gattcttatc atcggttcct agagagtaag
    11941 ggaattcaag catccatgtc acgtaagggc aacagccaag acaacggtag gatggaatct
    12001 ttctttggca ttttaaaatc cgaaatgttt tatggctatg agaaaacatt taaatcactt
    12061 aatcaattgg aacaagccat tatagactat attgattact acaacaacaa acgaattaag
    12121 gtaaaactaa aaggacttag tcctgtgcag tacagaacta aatcctttgg ataaattatt
    12181 tgtctaactg tttgggggca gtacagaact ggcattttat tttttaggat cttgatgggt
    12241 taggttcaat ccccaaggga ccaaattttc agttttattt ttgatacgag ctatattgtc
    12301 cttatgacga atgataatca aactagcaag tgctaagata atagcgatga agagagagtc
    12361 atagttactc aggataaaac caaaaagtgg aaagagcaga accccgataa cagccgcaat
    12421 cgatgctgtg acactagaca gtgaaatcat actgccaaga tagagagctc caaagaagat
    12481 aatcgcaagg tagagacaga agataggcgc aaatccgaaa atcactccag cactggttgc
    12541 gacagcctta ccacctttaa atcctgcaaa gatagggaag gtatggccga taacagccaa
    12601 aagtccaaag atgagaggag aaacgccttg tagatgaaaa ataatcggaa gcagcgttgc
    12661 tagggttcct ttgaaaaagt caatcacaaa ggttgccata ccagctttct tacctaaaat
    12721 gcggaaggtg ttggtcgttc cagtgttacc agaaccatgc tcgcgtagat tgatttgaaa
    12781 gaatacttgt ccaatccaga gaccagatgg aatcgaaccc agcagatagg ctaggattaa
    12841 taaaactatt gtaatcatac tcctattata tcatgaattg ggaaagaaaa gcagagaatc
    12901 tctgctgaaa ttgtcacatc ggagaaagaa aaattttgca aaatccttgg aaaacctgta
    12961 gaatagtaaa gatgaacgaa taggaggttc cttgtgtcaa aaaaggaaat caatattaac
    13021 aattataatg atgatgctat tcaggtgcta gaagggttgg atgcggtccg aaaacgtcca
    13081 gggatgtata ttggatcgac cgatggcgct ggtcttcatc acctagtttg ggaaatcgtt
    13141 gataatgcag tcgatgaagc cttgtctggg tttggtgatc gtattgatgt aactatcaat
    13201 aaagacggta gtctaacggt tcaagaccat ggacgtggga tgccgacagg tatgcacgct
    13261 atgggaattc caactgttga ggttatcttt accattcttc atgccggagg gaaattcggt
    13321 caaggtggct ataagacatc aggtggactt cacggagtgg gttcttccgt tgttaacgcc
    13381 ctttctagct ggttagaagt tgaaattacc cgtgatggcg cagtttacaa gcaacgtttc
    13441 gaaaatggtg gaaaacctgt cacgactttg aagaaaatcg gtacagcacc caagtctaaa
    13501 acaggcacca aagttacttt tatgcctgac gcgactatat tttctacgac agatttcaag
    13561 tacaatacca tttcagagcg ccttaatgaa tcagcctttc tcttgaaaaa tgtgaccttg
    13621 tctttaacgg acaagcgaac aaatgaagcg attgagttcc actatgagaa tggagtacaa
    13681 gattttgttt cttatctcaa cgaagataag gaaatcttga cgccagttct ttactttgaa
    13741 ggggaagaca atggttttca agtggaagta gccctccagt acaatgacgg attctcagat
    13801 aacattctat cttttgtcaa taacgttcgc accaaggacg gtggaacgca cgagacagga
    13861 ctcaagtctg ccattaccaa ggtcatgaat gactatgcac gtaaaacagg tcttctcaag
    13921 gaaaaagata aaaaccttga aggttcagac tatcgtgagg gactagcggc cgttctttct
    13981 atcttagttc ctgaagaaca cttgcagttt gaaggacaga ccaaggataa actaggaagc
    14041 cccctagctc gcccagttgt ggatggaata gtggctgata agttgacctt tttccttatg
    14101 gaaaatgggg aattagcttc taacctcatc cgcaaggcta tcaaggcccg tgatgctcgt
    14161 gaagcagcac gtaaggcgcg tgatgagagc cgaaatggga agaaaaacaa gaaagataag
    14221 ggcttgttgt ctgggaaatt gaccccagcc caatctaaga atcctgctaa gaatgaactc
    14281 tatctagttg agggggactc tgccggtggt tctgccaaac aaggtcgtga ccgcaagttc
    14341 caggctattc tacctcttcg tggtaaggtt gtcaatacag ccaaggccaa gatggcggat
    14401 atcctcaaaa atgaagagat caataccatg atttatacca ttggtgcggg tgttggagca
    14461 gacttctcta ttgaagatgc caactatgat aagatcatta tcatgaccga tgcggatacc
    14521 gacggtgccc atatccagac cttgctcttg acatttttct accgttacat gcgtccgcta
    14581 gtcgaggcag gtcatgtcta tattgccctc ccacctcttt acaagatgtc caaaggtaaa
    14641 ggcaagaaag aagaagtggc ctacgcttgg acggacggag aactagaaga actccgtaaa
    14701 cagttcggta aaggcgctac cctccaacga tacaaaggac ttggtgagat gaatgcggac
    14761 cagctctggg aaacaaccat gaacccagaa acacgtaccc tcatccgtgt cacaattgaa
    14821 gatttagcgc gcgccgaacg ccgcgtcaat gttctcatgg gagataaggt agaaccacgc
    14881 cgtaaatgga ttgaagataa tgtcaagttt acgctagaag aaacgacagt gttttaatga
    14941 aagaaaataa tatgttagta aactggaaat tagagtcgga tgtgaatgac tatgtgaaaa
    15001 agcagtttga aaatcttggt ttgaaaaaat tgcaggatta ttaatgaaga atctgctatg
    15061 agtgcttatc tcaaagaggc gcttaaggga gcggctaaga cacaaactaa gactaatttt
    15121 ggaaaaccag attttcatat tgaaaaatac aaacaggata gtttggttac ttatcgtaac
    15181 tgaacacggg aggaattccc gtaaaatatc ttttactgca taaaaaccta ctctacattc
    15241 tttgaaagga gttgaacacg ccctagatac tgtgtgaaaa agataaattc tcttgtgagt
    15301 ttgcttactt caagaatttt ctattttcac ttggtatttt atgggctttg tatcttatgt
    15361 ctaacattca aaacatgtcc ctggaggaca tcatgggaga gcgctttggt cgctactcca
    15421 agtacattat tcaagaccgg gctttgccag atattcgtga tgggttgaag ccggttcagc
    15481 gccgtattct ttattctatg aataaggata gcaatacttt tgacaagagc taccgtaagt
    15541 cggccaagtc agtcgggaac atcatgggga atttccaccc acacggggat tcttctatct
    15601 atgatgccat ggttcgtatg tcacagaact ggaaaaatcg tgagattcta gttgaaatgc
    15661 acggtaataa cggttctatg gacggagatc ctcctgcggc tatgcgttat actgaggcac
    15721 gtttgtctga aattgcaggc taccttcttc aggatatcga gaaaaagaca gttccttttg
    15781 catggaactt tgacgatacg gagaaagaac caacggtctt gccagcagcc tttccaaacc
    15841 tcttggtcaa tggttcgact gggatttcgg ctggttatgc cacagacatt cctccccata
    15901 atttagctga ggtcatagat gctgcagttt acatgattga ccacccaact gcaaagattg
    15961 ataaactcat ggaattcttg cctggaccag acttccctac aggggctatt attcagggtc
    16021 gtgatgaaat caagaaagct tatgagactg ggaaagggcg cgtggttgtt cgttccaaga
    16081 ctgaaattga aaagctaaaa ggtggtaagg aacaaatcgt tattattgag attccttatg
    16141 aaatcaataa ggccaatcta gtcaagaaaa tcgatgatgt tcgtgttaat aacaaggtag
    16201 ctgggattgc tgaggttcgt gatgagtctg accgtgatgg tcttcgtatc gctatcgaac
    16261 ttaagaaaga cgctaatact gagcttgttc tcaactactt atttaagtac accgacctac
    16321 aaatcaacta caactttaat atggtggcga ttgacaattt cacacctcgt caggttggga
    16381 ttgttccaat cctgtctagc tatatcgctc accgtcgaga agtgattttg gcgcgttcac
    16441 gctttgacaa agaaaaggct gagaaacgtc tccatatcgt cgaaggtttg attcgtgtga
    16501 tttcgatttt ggatgaagtc attgctctta tccgtgcttc tgagaataag gcggacgcca
    16561 aggaaaacct caaagttagc tatgatttta cggaagaaca ggctgaggct atcgtaactt
    16621 tgcaactgta ccgtttgacc aataccgatg tggttgtctt gcaggaagaa gaagcagagc
    16681 ttcgtgagaa gattgctatg ctggcggcta ttatcggtga tgaaaggact atgtacaatc
    16741 tcatgaagaa agaacttcgt gaggtcaaga agaaatttgc aactcctcgt ttgagttctt
    16801 tagaagacac tgcgaaagca attgagattg atacagctag tcttatcgct gaggaagata
    16861 cctacgtcag cgtgaccaag gcaggttaca tcaagcgtac cagtccacgt tcctttgcgg
    16921 cttccacctt ggaagaaatt ggcaagcgtg atgatgaccg tttgattttt gttcaatctg
    16981 ccaagacaac ccagcacctc ttgatgttca caagtcttgg aaatgtcatc tacagaccaa
    17041 tccatgagtt ggcagatatt cgttggaagg acatcggaga gcatctgagc caaaccatca
    17101 caaactttga aacgaatgaa gaaatccttt atgtggaagt actggatcag tttgacgatg
    17161 cgacaaccta ctttgcagtg actcgccttg gtcaaatcaa acgggtagag cgaaaagaat
    17221 tcactccatg gcggacctat agatctaagt ctgtcaagta tgctaagctc aaagacgata
    17281 cagatcagat tgtagcagtg gctccgatta aactagatga tgttgtcttg gttagtcaaa
    17341 atggttatgc cctgcgtttc aatatcgaag aggttccggt tgtcggtgct aaggcagcag
    17401 gtgtcaaggc tatgaatttg aaagaagatg atgtcctcca atctggcttt atctgtaata
    17461 cttcgtcctt ctacctcttg acccagcgtg gaagcttgaa acgtgtttcc attgaggaaa
    17521 ttctagcaac cagccgtgcc aaacgaggat tacaagtctt gcgtgagttg aaaaacaaac
    17581 cgcatcgtgt cttcttggca ggagcagttg cagagcaagg atttgttggc gatttcttca
    17641 gtacggaagt ggatgtgaac gaccaaactc tgcttgtcca atccaataaa ggaacaatct
    17701 atgaaagccg attgcaagac ttgaacttgt cagaacgcac tagcaatgga agcttcattt
    17761 ctgacacgat ttcagatgaa gaagtttttg acgcttatct tcaggaagta gttactgaag
    17821 ataaataagt gaaatgaaga atcagttcta agagttggtt tttattggag aaattttctg
    17881 aaaattacaa aatatacttg ctattttaga aaaatagtgt agaatataag aaataggttt
    17941 ttagaataag gagtggaata tgacagtaac gattgattgg gaaaacctcg gtttttccta
    18001 tatgaaatta ccttatcgct atcttgctca tttcaaaaat ggacaatggg atcaaggaga
    18061 gcttacagag gatgcaactt tgcatatttc agagtcttct ccaagtcttc actatggaca
    18121 acaagcattt gaaggtttga aagcttatcg tactaaggat ggcagtgttc aactgttccg
    18181 tcctgatgaa aatgctaaac gtctgcaacg tacatgtgac cgtctcttga tgccacaagt
    18241 tccgacagac atgtttgtag aagcttgtaa agcagttgtc cgtgcgaatg aagaatacgt
    18301 accaccatac ggaacaggtg gaaccttata tcttcgccct cttttgattg gtgtcggaga
    18361 tattatcggg gtaaaaccgg cagaagagta cattttcacc atctttgcta tgccagttgg
    18421 aaattacttt aaaggtggtt tggtcccaac caacttcttg attcaggatg agtacgaccg
    18481 tgcagcacca aatggtacag gtgcggctaa ggttggtgga aactatgctg caagtctctt
    18541 accaggaaaa atggccaagt cacgtcattt ctcagatgtt atctatctgg acccatcaac
    18601 tcatacaaag attgaagaag tcggatcagc taacttcttt ggaattacag ctgataatga
    18661 atttgtaaca ccattgagtc catctatctt gccatctatt accaagtatt ccttgcttta
    18721 tttggcagaa catcgcttgg gattaactcc tattgagggt gatgttccaa ttgataatct
    18781 tgaccgtttt gtagaggcag gtgcctgtgg tacagcagcg gttatttctc caattggagg
    18841 tattcaacat ggtgatgatt tccatgtatt ctatagtgaa acagaagtag gtcctgtgac
    18901 gcgtaaatta tataatgaat tgacgggtat tcagtttggc gatattgaag cgccagaagg
    18961 ttggattgta aaagtagatt aaaataaacc aaaggagatt ctttatgaaa tagaaaaagt
    19021 ggctcttaac agcaggagtg gtcctgagca cgtcagctat tttagtggct tgtggaaaaa
    19081 ctgataaaga agcagatgca ccgacaacat tttcttatgt ctatgcagta gatccagcat
    19141 cattgggcta cagtatagcg actcgaacat cgaggacaga cgttattgga aatgttattg
    19201 atggtttgat ggaaaatgat aaatacggca atgttgctcc ttctcaaaaa gactatgatt
    19261 tgaacagtac aggatgggct ccaagctatc aagatccagc gtctcacttg aatattatag
    19321 atccaaaatc tggttctgcc atgaaacacc ttggtattac gaaaggaaaa gataaggatg
    19381 ttgtagctaa acctggtttg gataaatata agaaattgtt agaagatgct gtttctgaga
    19441 ccactgacct agagaaaaga tatgaaaaat atgccaaagc tcaagcttgg tcgacagata
    19501 gttcattatt gatgccaaca gcttcatctg gtggttctcc agttgtaagt aacgtagtac
    19561 cattctcaaa accatactca caagttggta ttaaggggga tccatatatc tttaaaggaa
    19621 tgaaattgca aaaagatatt gttacaacaa aagaatataa cgaggttttt aaaaaatggc
    19681 aaaaagaaaa attggaatcc aatagcaaat accaaaaaga actagaaaaa cacattaaat
    19741 aaggaatggt attgatcttg ataaaatttt aaaaatactg tcattttgaa tataaaggag
    19801 tttgatatgg agtggattag attaatagga atagcaatca ttgttgtggg ttttatttta
    19861 aaatttgata caattgcaac agtagtctta gctggtttgg ttacagcttt agtttcaggt
    19921 gtttctctcg ttgaattttt ggagattttg ggaaaagaat ttagcaatca gcgagtgctc
    19981 acgattttta tggttacctt gcctcttgtg gggctgtcag aaacctttgg actcaagcaa
    20041 cgatcaatcg atttgattcg aaagattaaa ggtctgacag ttggaaactt ctatacagtt
    20101 tatttcttta ttcgagagtt agctggtttc ttttcaattc gtctaggagg acaccctcag
    20161 tttgtcagac ctttggttca acctatggga gaagcagctg cagagtctca attaggtaga
    20221 aagttaacag aggttgaaga tgagacaata aaagcgcgtg cggctgcgaa tgaaaatttt
    20281 ggaaatttct ttgctcaaaa tacgtttgta ggtgctgggg gagtcctctt gataggggga
    20341 acattagatc agttaggcta tgaaagcaat tatgcaggga ttgcttctac atctattatt
    20401 gttgctgtta taacacttat tgtagtgggg atttataatt atttatttga taaaaaattg
    20461 atatcaaaaa agactagggg aggagaacaa aaatgacaga gttggcaaag caactattag
    20521 agttgaccta tattgtgatt ggttgtcaat ttctccatac agcctattgt agttataaag
    20581 ataaaacaaa cccagttcga cttgggacat ctgcattttg gactctattg tctattacgt
    20641 ttataggtgg ttcctatatg ccaaatatga gtattggtat tattgtaatc ctattatcgc
    20701 tgttaacatt gtttaagcaa gtccgtatcg gaaccttgcc atccttagat gaaatgaaag
    20761 ccaatattga atctaacagg ttgaaaaata aaatttttat tccagttatg ctgatggcaa
    20821 tacttgcgtt ggtcttagcg caaatgattc cagaatttag caagatttcg attagccttg
    20881 ccgccttgtt tgctacaatt tctgttcttg tgattaccaa tagtcaccct aagagtctgt
    20941 tatcagaaaa taatcgaatg actcagcaag tttcaacaag tgggattgtt cctcaattat
    21001 taggggcttt gggggctatt tttactgtag caggtgttgg tgatgttatc tctcatctga
    21061 ttagcggtat tgttccttca gatagtcgct ttataggagt tttggcctat gttcttggaa
    21121 tggttctatt cacaatgatt atgggaaatg cttttgcagc attcaccgtt attacagcag
    21181 gtgttggagt tccctttgta tttgctctgg gagctaatcc aattgtggct ggtgctcttg
    21241 ccatgacagc aggttattgt gggaccttat tgaccccaat ggctgctaat tttaacgctc
    21301 taccagcagc attgatggat atgaaagatc agaatggcgt tataaaggct caagcaggtg
    21361 ttgctctagt aatgattgtt attcacatat tcttaatgta ctttctcgca ttttagtaaa
    21421 ggaaaataaa atgaaaatat tggttacagg ttttaatcct tttggaggtg aaaagattaa
    21481 tccagctttg gaggctgtaa aattattacc atctgagatt aatggggctg aagttcgctg
    21541 ggtagaaatt ccaacggttt tttataagtc gtcagaagtt ttagaggcag aaatattacg
    21601 atatcaacca gatgctgtac tttgtattgg acaagcaggc ggcaggaccg gcttaacacc
    21661 tgaacgagtg gctattaatc aagatgatgc tcgcatacct gataacgaag gcaatcaacc
    21721 aattgataca ccgattcgta ttgatggagc atcggcctat tttagtagtt tacctatcaa
    21781 agcgatggta caagctatca aaaaacaggg acttccggca gttgtatcca atagtgcagg
    21841 aacctttgtt tgcaatcatt tgatgtacca agctctttat ttagtggata aaaaattccc
    21901 taatatgaga gcaggtttca tgcatattcc atatatgatg gaacaagtaa taaataagcc
    21961 gaatactgca ggaatgagtc tatgtgatat tgtaagaggc atagaggtag ctattgaagc
    22021 tattgtagac tacaaagata aggatttgca gttagtaggc ggtgagactc actgataacc
    22081 taaaaaggat agtcaattat gcttgtttac taactattaa ctatgctaaa tcaattgagg
    22141 ttgtttacat aaaactctat atcagagaag cctgatatag agttttttct tgctagtttt
    22201 aggatttttt tgtaaaatag aaaaagtgaa gagaggtatg aaatgagcaa gaaagataaa
    22261 aaaatcgaaa ttcaagtagc ggatgccaaa gttaatgttg gtaaagacag ttttgaaggt
    22321 tatacattga ctatcggtaa aaaagttatc ggagaaattg ccgaattaga cggacaattt
    22381 gccattataa agaatgggaa tgtcgatagt ttttataaaa aattggaaaa agctgtggaa
    22441 attttgattg aaaattataa tttagcaaaa taagtcttgt ttttttgaaa ttttcatgat
    22501 ataatagtcc atgttgattg taggagagat agcgaagagg ctaaacgcgg cggactgtaa
    22561 atccgctcct tcgggttcgg gggttcgaat ccctctctct ccatttcatt aatggggtat
    22621 agccaagcgg taaggcaagg gactttgact ccctcatgcg ttggttcgaa tccagctacc
    22681 ccagttctta ggtaataatc aagatagaaa gcaaaatatc ttagggtatt ttatttttat
    22741 aattgaaaga cgtgaatgat atgaacatgt ccttgcgggt gcttaggaaa aaaattataa
    22801 gtatgtcaag tttaagaaaa acttgattgt tggaggattt tttagatgaa cgaatttgaa
    22861 gatttgctaa atagcgttag tcaagttgag actggtgatg ttgttagtgc tgaagtattg
    22921 acagttgatg cgactcaagc taacgttgca atctctggaa ctggtgttga aggtgtcttg
    22981 actcttcgcg aattgacaaa cgatcgtgat gcagatatca atgactttgt taaagtagga
    23041 gaagtattgg atgttcttgt acttcgtcaa gtagttggta aagatactga tacagttaca
    23101 taccttgtat ctaaaaaacg ccttgaagct cgcaaagcat gggacaaact tgttggtcgc
    23161 gaagaagaag ttgttactgt taaaggaacg cgtgccgtta aaggtggact ttcagtagaa
    23221 tttgaaggtg ttcgtggatt tatcccagct tcaatgttgg atactcgttt cgtacgtaac
    23281 gctgagcgtt ttgtaggtca agaatttgat actaaaatca aagaagttaa cgctaaagaa
    23341 aaccgcttca tcctttcacg tcgtgaagtt gttgaagcag ctactgcagc agctcgcgct
    23401 gaagtattcg gtaaattggc tgttggtgat gttgtaactg gtaaagttgc tcgtatcaca
    23461 agcttcggcg ctttcgtcga ccttggtggt gttgacggat tggttcactt gactgaattg
    23521 tcacatgaac gtaatgtatc accaaaatca gttgtaactg ttggtgaaga aattgaagtg
    23581 aaaatccttg atcttaacga agaagaagga cgtgtatcac tttcacttaa agcaacagta
    23641 ccaggaccat gggatggcgt tgagcaaaaa ttggctaaag gtgatgtagt agaaggaaca
    23701 gttaaacgtt tgactgactt cggtgcattt gttgaagtat tgccaggtat cgatggactt
    23761 gttcacgtat cacaaatttc acacaaacgg attgaaaatc caaaagaagc tcttaaagtt
    23821 ggtcaagaag ttcaagttaa agttcttgaa gttaacgcag atgcagaacg cgtgtcactt
    23881 tctattaaag ctcttgaaga acgtccagcc caagaagaag gacaaaaaga agaaaaacgt
    23941 gctgctcgtc cacgtcgtcc aagacgtcaa gaaaagcgtg atttcgaact tccagaaaca
    24001 caaacaggat tttcaatggc tgatttgttt ggtgatatcg aactttaatc aaattgaaaa
    24061 ttcacaaaat cctttgttta ctaaacaagg gatttttctg gctctttgtc aactgtagtg
    24121 ggttgaagaa aagctaagct cgagaaagga caaattttgt cctttctttt ttgatattca
    24181 gagcgataaa aatccgtttt ttgaagtttt caaagttccg aaaaccaaag gcattgcgct
    24241 tgataagttt gatgagatta ttggtcgctt ccagtttggc gttagaatag tgtagttgaa
    24301 gggtgttgac aagcttttct ttatctttga ggaaggtttt aaagacagtc tgaaaaatag
    24361 gatgaacctg cttaagattg tcctcaataa gtccgaaaaa tttctccggt tccttattct
    24421 gaaagtgaaa cagcaagagt tgatagagct gatagtggtg tttcaagtct tccgaataac
    24481 tcaaaagctt gtttaaaatc tctttattgg ttaagtgcat acgaaaagta ggacgataaa
    24541 atcgcttatc actcagttta cgactatcct gttgtatgag cttccagtag cgcttgatag
    24601 ccttgtattc atgagacttt cgatgaaact gattcatgat ttggacatgc acacgactca
    24661 tagcacggct aagatgttgt acaatatgaa agcgatcaag aacgatttta gcattcggga
    24721 gtgaaacagt ctgggagact gtttcagcct gagcctagaa atttgaaagc gaagttgtct
    24781 agctaagtca tagtaagggc taaacatatc catagtaatg attttgacgc gacatcggac
    24841 ggctctatca tatttaagaa agtgatctcg gatgatagct tgtgttctac cttcaagaac
    24901 agtgatgata tcgagcttgt caaaatcttg cgcaataaag ctcatct
//
LOCUS       DAVFER010000027        24737 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1105170250
            SAMEA2167659-rid19724873.denovo.027, whole genome shotgun sequence.
ACCESSION   DAVFER010000027 DAVFER010000000
VERSION     DAVFER010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2167659
            Sequence Read Archive: ERR388902
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 24737)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24737)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928716.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928716.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 04:07:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,118
            CDSs (total)                      :: 2,073
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 120
            CDSs (without protein)            :: 120
            Pseudo Genes (ambiguous residues) :: 0 of 120
            Pseudo Genes (frameshifted)       :: 67 of 120
            Pseudo Genes (incomplete)         :: 47 of 120
            Pseudo Genes (internal stop)      :: 34 of 120
            Pseudo Genes (multiple problems)  :: 23 of 120
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24737
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2167659-rid19724873.denovo.027"
                     /strain="1105170250"
                     /db_xref="taxon:1313"
     gene            <1..593
                     /locus_tag="VU534_001251"
     CDS             <1..593
                     /locus_tag="VU534_001251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000362880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HEU1513837.1"
                     /translation="FRHDYAGMLVSMQMAIDSGNLQEIDRIYNEVLVKANHKLRSDKY
                     TYFDLNNIEDSALRSLVAQSIVYARNNGVEFTLEVKDTITKLPIELLDLVRIMSVLLN
                     NAVEGSADSYKKQMEVAVIKMETETVIVIQNSCKMTMTPSGDLFALGFSTKGRNRGVG
                     LNNVKELLDKYNNIILETEMEGSTFRQIIRFKREFE"
     gene            590..1342
                     /locus_tag="VU534_001252"
     CDS             590..1342
                     /locus_tag="VU534_001252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000866085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU1513838.1"
                     /translation="MKVLILEDVIEHQVRLERILDEISKESNIPISYKTTGKVREFEE
                     YIENDEVNQLYFLDIDIHGIEKKGFEVAQLIRHYNPYAIIVFITSRSEFATLTYKYQV
                     SALDFVDKDINDEMFKKRIEQNIFYTKSMLLENEDVVDYFDYNYKGNDLKIPYHDILY
                     IETTGVSHKLRIIGKNFAKEFYGTMTDIQEKDKHTQRFYSPHKSFLVNIGNIREIDRK
                     NLEIVFYEDHRCPISRLKIRKLKDILEKKSQK"
     gene            1394..1465
                     /locus_tag="VU534_001253"
     tRNA            1394..1465
                     /locus_tag="VU534_001253"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1427..1429,aa:Glu,seq:ttc)
     gene            1471..1544
                     /locus_tag="VU534_001254"
     tRNA            1471..1544
                     /locus_tag="VU534_001254"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1505..1507,aa:Asn,seq:gtt)
     gene            complement(1585..2127)
                     /locus_tag="VU534_001255"
     CDS             complement(1585..2127)
                     /locus_tag="VU534_001255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator
                     C-terminal domain-containing protein"
                     /protein_id="HEU1513839.1"
                     /translation="MQESNKRLKTKRTIENAMVQLLMEQPFDKISTVKLVEKAGISRS
                     SFYTHYKDKYDMIEHYQSKLFHTFEYIFQKHAHHKRDAILEVFEYLESEPLLAALLSE
                     NGTKEIQNFLRNKLHIMLSTDLQKRFMQLNLNTTELEYSSIYLTHALFGVCQTWIAHG
                     KKESSQEITDFLMKMLGDTN"
     gene            2306..3073
                     /locus_tag="VU534_001256"
     CDS             2306..3073
                     /locus_tag="VU534_001256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip domain-containing protein"
                     /protein_id="HEU1513840.1"
                     /translation="MIGISLIPDLYNIIFLSSMWDPYGQLSDLPVAVVNNDKEASYNG
                     NTMAIGKDMVSNLKENKTLDFHFVDEEEGKKGLEDGDYYMVVTLPSDLSEKTTTLSNI
                     QSTAAYQSLTSEQQTEISDSVSQNSTDSIQSAQSIVALVQDLQGSLENLQNQSSNLST
                     LKNQSNQVSPITSTSLIGLSSGLTEIQGDVTSKLVPASQSIASGVNAYTTGVDKVSQG
                     ASQLSEKNATLTGSLDKLVSGSNTLTQKSSRLTAGVG"
     gene            3158..3433
                     /locus_tag="VU534_001257"
     CDS             3158..3433
                     /locus_tag="VU534_001257"
                     /inference="COORDINATES: protein motif:HMM:TIGR03057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1513841.1"
                     /translation="MADGSGKLAEGGTKLTSGLEDLQTGLASLGQGLGNASDQLKSVS
                     TESKNAEILSNPLNLSKTDNDQVPVNGIAIAPYMISVALFLQQYQQI"
     gene            3523..3837
                     /locus_tag="VU534_001258"
     CDS             3523..3837
                     /locus_tag="VU534_001258"
                     /inference="COORDINATES: protein motif:HMM:TIGR03062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip family protein"
                     /protein_id="HEU1513842.1"
                     /translation="MAGILVYGGVQLIGLTANHEMRIFILIILTSLVFMSMVTTLATW
                     NSRIGAFFSLILLLLQLASSAGTYPLALTNDFFRSINPWLPMSYSVSGLRQTISINKS
                     FS"
     gene            complement(3938..6490)
                     /locus_tag="VU534_001259"
     CDS             complement(3938..6490)
                     /locus_tag="VU534_001259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HEU1513843.1"
                     /translation="MKSFLKTYRTYFISFIIPVVIMSGVYLSQSIYWNSDNSPLLGDG
                     FHQYVIFDVALRNILHGNSNLFYTFTSGLGLNFYALSSYYLGSFLAPLVYFFDLTNMP
                     DAIYLTTLLKFGLIGLSTFFSLNKLFQSIPQILKLALSTSYALMSFTVSQLEIKTWLD
                     VFILIPLIITGLHLLITEKKLLLYFTSLSILFIQNYYFGYMTVLFLIFWYLCQISWDF
                     KTRKSSVLDFIVISFLAGMASLIMTLPTLFDLQTHGEKLTEVTKFQTESSWYLDLFAK
                     QFIGSFDTTKYGAIPMIFVGLFPFILTILFFTLKSIKFHVKLIYVIFFAFLIASFYIE
                     ALDLFWQGMHTPNMFLHRYAWIFSTLLIYTAAEVLKRLKELKVWNFLVSLFLVVAGFL
                     ATIYLKSHYSFLTDLNILLTLEFLVVYSLLLLAVIKKFISVNLFAILISLFILVEMSL
                     NASSQMDGIAKEWGFASRSAYSRDIPAMESFSTYIGNQFTRTEKLQTQTGNDSMKFNY
                     NGISQFSSVRNRSSSSTLDKLGFKSSGTNLNLRYANNSILADSLFGIQYNISDSPIDK
                     YGFKDIYQKDNLTLYENQYSLPIAVASQSVYNDVKFNEHTLDNQASFLNQLANVNFDY
                     FSPIPYEKTEKIENTNDLISVTSSSNEDAAIQYQIEVPENSQVYLSFINLHFSNDKQK
                     KVDILVNGEKKTFTTDNVFSFFNLGYTKEKKTFNINVSFPGNSQVSFESPTFYRLDTK
                     TFTEAIQKIKEQPVTVSTSKNKVFATYDVQQDTSIFFTIPYDKGWSAYQDGKKIEIKQ
                     AQTGFMKVDIPKGKGTITLSFIPNGFITGAICSFTSLLLFGIYNHRRKSSKA"
     gene            complement(6552..8174)
                     /locus_tag="VU534_001260"
     CDS             complement(6552..8174)
                     /locus_tag="VU534_001260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEU1513844.1"
                     /translation="MLTVSDVSLRFSDRKLFDDVNIKFTEGNTYGLIGANGAGKSTFL
                     KILAGDIEPTTGHISLGPDERLSVLRQNHFDYEDERAIDVVIMGNEKLYSIMKEKDAI
                     YMKEDFSDEDGVRAAELEGEFAELGGWEAESEASQLLQNLNIPEELHYQNMSELANGE
                     KVKVLLAKALFGKPDVLLLDEPTNGLDIQSITWLEDFLIDFDNTVIVVSHDRHFLNKV
                     CTHMADLDFGKIKLYVGNYDFWKESSELAAKLLADRNAKAEEKIKQLQEFVARFSANA
                     SKSRQATSRKKMLDKIELEEIVPSSRKYPFINFKAEREIGNDLLTVENLTVKIDGETI
                     LDNISFILRPDDKTALIGQNDIQTTALIRAIMGDIDYEGTVKWGVTTSQSYLPKDNSA
                     DFAGGESILDWLRQFASKEEDDNTFLRGFLGRMLFSGDEVNKPVNVLSGGEKVRVMLS
                     KLMLLKSNVLVLDDPTNHLDLESISSLNDGLKNFKESIIFASHDHEFIQTLANHIIVL
                     SKNGVIDRIDETYDEFLENAEVQAKVKELWKD"
     gene            8380..9405
                     /gene="trpS"
                     /locus_tag="VU534_001261"
     CDS             8380..9405
                     /gene="trpS"
                     /locus_tag="VU534_001261"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000165445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HEU1513845.1"
                     /translation="MTKPIILTGDRPTGKLHIGHYVGSLKNRVLLQEEDKYDMFVFLA
                     DQQALTDHAKDPQTIVESIGNVALDYLAVGLDPNKSTIFIQSQIPELAELSMYYMNLV
                     SLARLERNPTVKTEISQKGFGESIPTGFLVYPIAQAADITAFKANYVPVGTDQKPMIE
                     QTREIVRSFNNAYNCDVLVEPEGIYPENERAGRLPGLDGNAKMSKSLNNGIYLADDAD
                     TLRKKVMSMYTDPDHIRVEDPGKIEGNMVFHYLDVFGRPEDAQEIADMKERYQRGGLG
                     DVKTKRYLLEILERELGPIRERRIEFAKDMGEVYNMIQKGSERAREVAGQTLSEVKGA
                     MGLHYFN"
     gene            9557..11035
                     /gene="guaB"
                     /locus_tag="VU534_001262"
     CDS             9557..11035
                     /gene="guaB"
                     /locus_tag="VU534_001262"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HEU1513846.1"
                     /translation="MSNWDTKFLKKGFTFDDVLLIPAESHVLPNDADLTTKLADNLTL
                     NIPIITAAMDTVTESQMAIAIARAGGLGVIHKNMSIAQQADEVRKVKRSENGVIIDPF
                     FLTPEHTIAEADELMGRYRISGVPVVETLENRKLVGILTNRDLRFISDYNQPISNHMT
                     SENLVTAPVGTDLATAESILQEHRIEKLPLVDEEGSLSGLITIKDIEKVIEFPNAAKD
                     EFGRLLVAGAVGVTSDTFERAEALFEAGADAIVIDTAHGHSAGVLRKIAEIRAHFPDR
                     TLIAGNIATAEGARALYEAGVDVVKVGIGPGSICTTRVIAGVGVPQVTAIYDAAAVAR
                     EYGKTIIADGGIKYSGDIVKALAAGGNAVMLGSMFAGTDEAPGETEIFQGRKFKTYRG
                     MGSIAAMKKGSSDRYFQGSVNEANKLVPEGIEGRVAYKGAAADIVFQMIGGIRSGMGY
                     CGAANLKELHDNAQFIEMSGAGLKESHPHDVQITNEAPNYSM"
     gene            complement(11086..12183)
                     /gene="recF"
                     /locus_tag="VU534_001263"
     CDS             complement(11086..12183)
                     /gene="recF"
                     /locus_tag="VU534_001263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000266665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HEU1513847.1"
                     /translation="MWLQHLSLKTFRNYKETKIDFNPKLNVFLGRNAQGKTNMLEAIY
                     FLALTRSHRTRTDKNLIHFDEEQLHLSGLVQKKTGSIPLEIELTQKGRVTKVNHLKQA
                     RLSDYVGHMNVVLFAPEDLQLIKGAPSIRRKFIDMELGQIKPIYLSDLTNYNHILKQR
                     NTYLKSAQKIDETFLSVLDDQLVDYGCRVMNHRLDFIKKLESFGRKKHFELSNQIEEL
                     SISYQSSVNITDKQNLSESFKIALEKSRSRDLFKKNTGVGPHRDDISFYINGMDASFG
                     SQGQHRSLVLSIKLAEIELMESITTESPILLLDDVMSELDNTRQLKLLETISQSIQTF
                     ITTTSLDHLQNLPENLSIFTIQDGKAAVNGN"
     gene            complement(12186..12554)
                     /gene="yaaA"
                     /locus_tag="VU534_001264"
     CDS             complement(12186..12554)
                     /gene="yaaA"
                     /locus_tag="VU534_001264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HEU1513848.1"
                     /translation="MEYKLFEEFITLQALFKELGITHSGGAIKSFLSEHSVYFNRELE
                     SRRGKKLRIGDKVDIPDMNIDILLTQPTSEEQDEYQADKVEKERIAKLVKKMNKGVKK
                     DKSKPASSPKSQQAPRFPGR"
     gene            12713..13963
                     /locus_tag="VU534_001265"
     CDS             12713..13963
                     /locus_tag="VU534_001265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HEU1513849.1"
                     /translation="MELVHGISTHFIQSKKFKTNKITVRFTAPLSLDTIAGHMLSASM
                     LETANQMYPTSQDLRRHLASLYGTDMSTNCFRRGQSHIIELTFTYVRDEFLSRKNVLT
                     SQILELVKETLFSPVVVDNGFDPALFEIEKKQLLASLAADMDDSFYFAHKELDKLFFH
                     DERLQLEYSDLRNRILAETPQSSYSCFQEFLANDRIDFFFLGDFNEVEIQNVLESFGF
                     KGRKGDVKVQYCQPYSNILQEGMVRKNVGQSILELGYHYCSKYGDEQHLPMIVMNGLL
                     GGFAHSKLFTNVRENAGLAYTISSELDLFSGFLRMYAGINRENRNQARKMMNNQLLDL
                     KKGYFTEFELNQTKEMIRWSLLLSQDNQSSLIERAYQNALFGKSSADFKSWIAKLEQI
                     DKDAICRVANNVKLQAIYFMEGIE"
     gene            13960..15243
                     /locus_tag="VU534_001266"
     CDS             13960..15243
                     /locus_tag="VU534_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HEU1513850.1"
                     /translation="MTKVVFEEKYYPAVKEMVYRTRLANGLTVALLPKKEFKEVYGSV
                     TVQFGSVDTFVTEVDGDVKQYPGGIAHFLEHKLFEREDSSDLMSAFTSLGADSNAFTS
                     FTKTNYLFSATDYFLENLDLLDELVTSAHFTEASILTEQDIIQQEREMYQDDPDSCLF
                     FSTLANLYPGTPLATDIVGSEESISQINLTNLQENFTKFYKPVNMSLFLVGNFDVERV
                     QDYFESKELKDSDFQEVAREKLFLQPVKPTDSMRMEVSSPKLAIGVRGKREVSEADCY
                     RHHILLKLLFAMMFGWTSDRFQKCYESGKIDASLSLEVEITSRFHFVMLTMDTKEPVA
                     LSHQFRKAIRNFTKDLDITEEHLDIIKREMFGEFFSSMNSLEFIATQYDAFENGEIIF
                     DLPKILQEITLEDVLDAGHHLIDDGDIVDFTIFPS"
     gene            15285..16106
                     /locus_tag="VU534_001267"
     CDS             15285..16106
                     /locus_tag="VU534_001267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEU1513851.1"
                     /translation="MRKKTIGEVLRLARINQGLSLDELQKKTEIQLDMLEAMEADDFD
                     QLPSPFYTRSFLKKYAWAVELDDQIVLDAYDSGSMITYEEVDVDEDELTGRRRSSKKK
                     KKKTSFLPLFYFILFALSILIFVTYYVWNYIQTQPEEPSLSNYSVVQSTSSTSSVPHS
                     SSSSSSSIESAISVSGEGNHVEIAYKTSKETVKLQLAVSDVTSWVSVSESELEGGVTL
                     SPKKKSAEATVATKSPVTITLGVVKGVDLTVDNQTVDLSKLTAQTGQITVTFTKN"
     gene            16117..16662
                     /gene="pgsA"
                     /locus_tag="VU534_001268"
     CDS             16117..16662
                     /gene="pgsA"
                     /locus_tag="VU534_001268"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HEU1513852.1"
                     /translation="MKKEQIPNLLTIGRILFIPIFIFILTIGNSIESHIVAAIIFAVA
                     SITDYLDGYLARKWNVVSNFGKFADPMADKLLVMSAFIMLIELGMAPAWIVAVIICRE
                     LAVTGLRLLLVETGGTILAAAMPGKIKTFSQMFAIIFLLLHWTLLGQVLLYVALFFTI
                     YSGYDYFKGSAYVFKGTFGSK"
     gene            16659..17486
                     /locus_tag="VU534_001269"
     CDS             16659..17486
                     /locus_tag="VU534_001269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HEU1513853.1"
                     /translation="MKSIIDVKNLSFRYKENQNYYDVKDITFHVKRGEWLSIVGHNGS
                     GKSTTVRLIDGLLEAESGEIVIDGQRLTEENVWNIRRQIGMVFQNPDNQFVGATVEDD
                     VAFGLENQGLSRQEMKKRVEEALALVGMLDFKKREPARLSGGQKQRVAIAGVVALRPA
                     ILILDEATSMLDPEGRRELIGTVKGIRKDYDMTVISITHDLEEVAMSDRVLVMKKGEI
                     ESTSSPRELFSRNDLDQIGLDDPFANQLKKSLSQNGYDLPENYLTESELEDKLWELL"
     gene            17471..18310
                     /locus_tag="VU534_001270"
     CDS             17471..18310
                     /locus_tag="VU534_001270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000510406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HEU1513854.1"
                     /translation="MGIALENVNFTYQEGTPLASAALSDVSLTIEDGSYTALIGHTGS
                     GKSTILQLLNGLLVPSQGSVRVFDTLITSTSKNKDIRQIRKQVGLVFQFAENQIFEET
                     VLKDVAFGPQNFGVSEEDAVKTAREKLALVGIDESLFDRSPFELSGGQMRRVAIAGIL
                     AMEPAILVLDEPTAGLDPLGRKELMTLFKKLHQSGMTIVLVTHLMDDVAEYANQVYVM
                     EKGRLVKGGKPSDVFQDVVFMEEVQLGVPKITAFCKRLADRGVSFKRLPIKIEEFKES
                     LNG"
     gene            18303..19097
                     /locus_tag="VU534_001271"
     CDS             18303..19097
                     /locus_tag="VU534_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000377903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEU1513855.1"
                     /translation="MDSMILGRYIPGDSIVHRLDPRSKLLAMMLLILIVFWANNPLTN
                     LILFIATGIFIALSGVSLSFFIQGLKSMFFLIAFTTIFQLFFISNGNVLFEFSFVRIT
                     DYALQQAGIIFCRFVLIIFFSTLLTLTTMPLSLASAVEALLAPLKRVKVPVHEIGLML
                     SMSLRFVPTLMDDTTRIMNAQKARGVDFGEGSIVQKVKAMIPILIPLFATSLKRADSL
                     AIAMEARGYQGGKGRSQYRQLKWTLKDTLTILVILVLGCCLFFLKS"
     gene            19156..19974
                     /gene="mreC"
                     /locus_tag="VU534_001272"
     CDS             19156..19974
                     /gene="mreC"
                     /locus_tag="VU534_001272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001078980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HEU1513856.1"
                     /translation="MNRFKKSKYVIIVFVTVLLVSALLATTYSSTIVTKLGDGISLVD
                     RVVQKPFQWFDSVKSDLAHLTRTYNENESLKKQLYQLEVKSNEVESLKTENEQLRQLL
                     DMKSKLQATKTLAADVIMRSPVSWKQELTLDAGRSKGASENMLAIANGGLIGSVSKVE
                     ENSTIVNLLTNTENADKISVKIQHGSTTIYGIIIGYDKENDVLKISQLNSNSDISAGD
                     KVTTGGLGNFNVADIPVGEVVATTHSTDYLTREVTVKLSADTHNVDVIELVGNS"
     gene            19974..20468
                     /gene="mreD"
                     /locus_tag="VU534_001273"
     CDS             19974..20468
                     /gene="mreD"
                     /locus_tag="VU534_001273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001249461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HEU1513857.1"
                     /translation="MRQLKRVGVFLLLPFFVLIDAHISQLLGSFFPHVHLASHFLFLF
                     LLFETIEVSEYLYLVYCFVIGLVYDVYFFHLIGITTLLFILLGAFLHKLNSVILLNRW
                     TRMLAMIVLTFLFEMGSYLLAFMVGLTVDSMSIFIVYSLVPTMILNFLWITVFQFIFE
                     KYYL"
     gene            20562..21740
                     /locus_tag="VU534_001274"
     CDS             20562..21740
                     /locus_tag="VU534_001274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HEU1513858.1"
                     /translation="MKKKILASLLLSTVMVSQVAVLTTAHAETTDDKIAAQDNKISNL
                     TAQQQEAQKQVDQIQEQVSAIQAEQSNLQAENDRLQAESKKLEGEITELSKNIVSRNQ
                     SLEKQARSAQTNGAVTSYINTIVNSKSITEAISRVAAMSEIVSANNKMLEQQKADKKA
                     ISEKQVANNDAINTVIANQQKLADDAQALTTKQAELKAAELSLAAEKATAEGEKASLL
                     EQKAAAEAEARAAAVAEAAYKEKRASQQQSVLASANTNLTAQVQAVSESAAAPVRAKV
                     RPTYSTNASSYPIGECTWGVKTLAPWAGDYWGNGAQWATSAAAAGFRTGSTPQVGAIA
                     CWNDGGYGHVAVVTAVESTTRIQVSESNYAGNRTIGNHRGWFNPTTTSEGFVTYIYAD
                     "
     gene            21964..22743
                     /gene="rpsB"
                     /locus_tag="VU534_001275"
     CDS             21964..22743
                     /gene="rpsB"
                     /locus_tag="VU534_001275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000268478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HEU1513859.1"
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMAKYIFTERNGIHVIDLQ
                     QTVKYADQAYDFMRDAAANDAVVLFVGTKKQAADAVAEEAVRSGQYFINHRWLGGTLT
                     NWGTIQKRIARLKEIKRMEEDGTFEVLPKKEVALLNKQRARLEKFLGGIEDMPRIPDV
                     MYVVDPHKEQIAVKEAKKLGIPVVAMVDTNTDPDDIDVIIPANDDAIRAVKLITAKLA
                     DAIIEGRQGEDAVAVEAEFAALETQADSIEEIVEVVEGDNA"
     gene            22822..23862
                     /locus_tag="VU534_001276"
     CDS             22822..23862
                     /locus_tag="VU534_001276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003053075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Ts"
                     /protein_id="HEU1513860.1"
                     /translation="MAEITAKLVKELREKSGAGVMDAKKALVETDGDIEKAIELLREK
                     GMAKAAKKADRVAAEGLTGVYVNGNVAAVIEVNAETDFVAKNAQFVELVNTTAKVIAE
                     GKPANNEEALALIMPSGETLEAAYVSATATIGEKISFRRFALIEKTDAQHFGAYQHNG
                     GRIGVISVVEGGDEALAKQLSMHIAAMKPTVLSYKELDEQFVKDELAQLNHVIDQDNE
                     SRAMVNKPALPHLKYGSKAQLTDDVIAQAEADIKAELAAEGKPEKIWDKIIPGKMDRF
                     MLDNTKVDQAYTLLAQVYIMDDSKTVEAYLESVNASVVEFARFEVGEGIEKAANDFEA
                     EVAATMAAALNN"
     gene            24108..24431
                     /gene="tnpB"
                     /locus_tag="VU534_001277"
     CDS             24108..24431
                     /gene="tnpB"
                     /locus_tag="VU534_001277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HEU1513861.1"
                     /translation="MIIQLSDLGQVHLVCGKTDMRQGIDSLAYVVKTHFELDPFSDQV
                     FLFCGGRKDRFKVLYWDGQGFWILYKRFENGKLTWSSTEKDVKALAPEQVDWLMKGFS
                     ITPQI"
     gene            complement(24572..>24737)
                     /locus_tag="VU534_001278"
     CDS             complement(24572..>24737)
                     /locus_tag="VU534_001278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS630 family transposase"
                     /protein_id="HEU1513862.1"
                     /translation="PEMNPIEQVWKEIRKRGFKNKAFRTLEDVIQGLEKEVIKSIVNR
                     RRTRMLFENR"
BASE COUNT         7926 a         3937 c         5032 g         7842 t
ORIGIN      
        1 gttttcgaca tgattatgct ggaatgcttg tcagcatgca gatggcaatt gacagtggta
       61 atttacagga aattgacaga atttacaatg aagttttagt caaagcaaat cataaattgc
      121 gttcagataa gtacacttac tttgatttga acaacataga agactcagct ttacgaagtt
      181 tggttgctca gtcaattgtc tatgctcgaa ataatggtgt agagtttaca ctggaagtaa
      241 aagatacgat taccaagctt ccaattgaac tattggattt ggttcgtatc atgagcgttt
      301 tattgaataa tgctgtcgaa ggatcggctg atagctataa aaagcagatg gaagtagcag
      361 ttattaagat ggaaactgaa acagttattg tgattcagaa ttcatgtaaa atgacgatga
      421 ctccttcagg agatctattt gccttaggat tctccactaa gggaagaaat cgcggagtcg
      481 gattaaataa tgtgaaagaa ctactagata agtacaacaa tattatttta gaaacagaga
      541 tggaaggcag tacatttaga caaatcatta gatttaagag ggaatttgaa tgaaagtttt
      601 aattttagaa gatgttattg aacatcaagt gagactagag agaatattgg atgaaatttc
      661 gaaagaatcg aatattccaa tatcatacaa gacaacggga aaagtccgtg aatttgaaga
      721 atacattgaa aatgatgaag taaatcagct ttatttccta gatatcgata ttcatggaat
      781 tgagaaaaag ggatttgaag tggctcagct cattcgtcat tacaatcctt acgctattat
      841 cgtctttatc actagtcgat cagagtttgc gactctaacc tataaatacc aggtatcagc
      901 cctagatttt gttgataagg atatcaatga tgagatgttt aagaagagaa ttgagcaaaa
      961 tatcttctac acgaagagta tgttacttga aaatgaagat gttgtagatt atttcgacta
     1021 caattacaag ggaaatgatt taaaaattcc ttaccatgat attttgtata ttgaaacaac
     1081 aggggtatct cataaattgc gcattattgg taagaatttt gcaaaagagt tttatggtac
     1141 catgacagat attcaggaaa aggacaaaca tactcagcga ttttattctc ctcacaagtc
     1201 atttttggta aatataggta atatcagaga aattgatcga aaaaacttag aaattgtttt
     1261 ctatgaagac catcgttgtc ctatttcaag attaaaaatt agaaaattaa aagatatttt
     1321 agagaaaaaa tctcaaaagt gattgacaat tagcaagaaa ttgatataat ggttatatct
     1381 gctacagata gaaggtccgt tggtcaaggg gttaagacac cgccttttca cggcggtaac
     1441 acgggttcga atcccgtacg gactatttta tccgccatag ctcagttggt agtagcgcat
     1501 gactgttaat catgatgtcg taggttcgag tcctactggc ggagtataga taaaagggaa
     1561 cacagctgtg ttcctctttt tgtatcaatt tgtatcacca agcattttca taaggaagtc
     1621 tgttatttct tgagaacttt ctttttttcc atgtgcaatc caagtttggc agacaccaaa
     1681 aagtgcatga gttagataga tgctactata ttctaattca gtggtattta gattcagttg
     1741 cataaatcgc ttttgtaaat ctgtactaag catgatatga agtttatttc gtaagaaatt
     1801 ttggatttct ttagtcccat tttcagaaag aagggcagcc agaagtggtt ctgactctag
     1861 atattcaaaa acttctaaaa tagcgtctct tttgtgatga gcatgttttt gaaaaatata
     1921 ttcaaatgta tggaatagct tgctttgata gtgctcaatc atatcatact tatccttata
     1981 gtgagtatag aagctggaac gactaattcc ggctttttct actaatttga cagtagaaat
     2041 tttatcaaat ggctgttcca tcagtaattg taccatagca ttttcaatag ttcgctttgt
     2101 ttttaagcgt ttgttacttt cttgcatatt tcctccttgt aaacaaatta gactatatgt
     2161 ctaaaaatag attttttatc ttgtaattta gattttttaa tgtataatct attatatcaa
     2221 aattttagac aatatgttta aaaaaggaga aactaagttt aaagaatgga aagcaattta
     2281 aaaaaaacca acctttatta ttgtcatgat cgggatttct cttattccag atctgtacaa
     2341 tatcatattt ttgtcatcaa tgtgggatcc atatgggcaa ttgtctgact tacctgtggc
     2401 agttgtaaat aatgataaag aggcttccta taatggtaat actatggcaa taggaaaaga
     2461 catggtgtcc aatttaaaag aaaataaaac cttggatttt cattttgtag atgaagagga
     2521 aggaaagaag ggattggaag atggcgatta ctatatggta gtgactttac caagtgattt
     2581 atctgaaaaa acaactacat tatccaatat tcaatcgaca gcagcttatc aatcattgac
     2641 aagtgagcaa caaactgaga taagtgattc tgtatctcaa aattcaactg atagtattca
     2701 atcggctcag tcaattgtag ctttagtaca agatttacag ggaagtttag aaaacttaca
     2761 aaatcaatct tctaatcttt cgactttaaa aaatcaatct aatcaagtat cacctattac
     2821 ttctacttct ttgataggat tgtcaagtgg attaacagag atacaaggag atgttactag
     2881 caaattagtt cctgccagtc agtcgattgc atcaggtgta aacgcatata ctacaggtgt
     2941 tgataaagtt tctcagggcg caagtcaact aagtgaaaaa aatgccacct tgacaggtag
     3001 tttggataaa ctagtttcag gctcaaacac cttgacacaa aaatcttcta gattgacagc
     3061 aggagttggt taattacaat caggatctgg gcaattagca gacaaatcca gtcagttact
     3121 ttcaggtgct tctccattag agaatagagc taataaattg gcagatggat ctgggaaact
     3181 agcagaaggt ggaacaaagt taacttctgg attggaagat ttacagacag gacttgcttc
     3241 tttaggacaa ggactaggta atgctagtga tcaactcaaa tcagtatcaa cagaatctaa
     3301 aaatgcagag attttgtcaa atccactcaa tctttcaaaa acagacaatg atcaagttcc
     3361 tgtaaatgga atcgcaatag ctccttatat gatatcagtt gctctttttt tgcagcaata
     3421 tcaacaaata tgatatttgc gaaattgcct tcaggacgtc atccagagag ccgttgggct
     3481 tggttgaaat cttgagctga aataaatggt attatagctg ttttggcagg aattttggta
     3541 tatggaggag ttcagcttat tggtttaact gctaatcatg agatgagaat atttattctc
     3601 atcatcctaa caagtttagt attcatgtct atggtgacca ctttagcaac gtggaatagc
     3661 cgtataggag cttttttctc acttattttg cttttactac agttagcatc aagtgcaggt
     3721 acttatccac ttgctttgac aaatgatttc tttagatcta ttaatccctg gttaccaatg
     3781 agctattcag tttcgggatt acgacaaaca atctctatca acaagtcatt ttcctagctg
     3841 tcatactagt tctatttact agtttaggta tgctagccta tcaacataag aaaatggaag
     3901 aagattaaaa aaatcgaccg attaactggt cgatttttta tgccttagat gactttcgtc
     3961 tgtgattata gattccaaat agtaagagag aagtaaagga acagattgct ccagtaataa
     4021 aaccattggg aatgaaggaa agtgtaatag ttcctttccc cttgggaatg tcaactttca
     4081 taaatccagt ttgagcttgt ttaatttcta ttttcttacc atcttggtag gcagaccaac
     4141 ctttgtcata aggaatggtg aagaaaatag atgtatcttg ttggacatca tatgtagcaa
     4201 aaaccttgtt tttagaagtt gatactgtga caggttgttc tttaattttt tgaattgcct
     4261 cggtgaaagt tttggtatct aaacgataga aggtaggaga ttcaaatgat acttgtgaat
     4321 ttccagggaa actaacattg atattgaaag tttttttctc tttagtatat cctagattaa
     4381 agaaggagaa gacattatca gttgtaaaag tctttttttc accatttaca aggatgtcaa
     4441 ccttcttttg tttatcgtta gaaaagtgaa ggtttatgaa agagagataa acttggctgt
     4501 tttctggaac ttcaatttga tactggattg ctgcatcttc atttgaagaa cttgtgacac
     4561 taatcaaatc attagtattt tctatttttt ctgttttttc ataaggtatt ggagaaaaat
     4621 aatcaaaatt gacgttagca agttgattta aaaatgaggc ctgattatcc aaggtatgtt
     4681 cattgaactt gacatcattg taaacagatt gactcgcaac tgcaatcgga agagagtatt
     4741 gattttcata tagggtaaga ttatcttttt gatagatatc tttaaagcca tacttatcaa
     4801 taggactgtc tgagatattg tactggatac caaataaact atcagccaaa atactattat
     4861 ttgcatatcg gagattgaga ttagtcccag aggatttaaa accaagttta tctaaagtag
     4921 agcttgatga acgatttcga acagatgaaa attgagagat tccattgtag ttgaatttca
     4981 tactgtcatt tcctgtctga gtttgtagtt tttcagtacg agtaaattga tttccaatat
     5041 atgttgagaa agattccata gctgggatat ctcgactata agcacttcga gaagcaaatc
     5101 cccattcctt agcaattccg tccatttgag atgaagcatt taaactcatt tcaaccagta
     5161 taaataaaga gattagaatg gcaaatagat tcacagatat aaactttttg ataactgcaa
     5221 ggagtaaaag agaatagaca accaaaaatt caagagtaag cagaatattc aaatctgtta
     5281 aaaaagaata atgcgatttt agatagatgg tagctaaaaa tcctgctact acaagaaaaa
     5341 gcgaaactaa aaaattccag actttaagtt ctttcagacg ctttaagact tctgctgctg
     5401 tgtaaattaa caaggtagag aaaatccaag catagcgatg taaaaacatg tttggagtat
     5461 gcatgccttg ccaaaataag tcaagagctt ctatgtaaaa gcttgcaatt agaaatgcaa
     5521 agaatattac atatatgagt ttcacgtgaa acttaataga tttcagcgta aaaaataaaa
     5581 tggtcaaaat aaagggaaat agtccaacaa aaatcattgg gatggcccca tactttgttg
     5641 tgtcaaagga accaatgaat tgcttagcaa agagatcaag ataccagcta ctttcagttt
     5701 gaaactttgt aacttcagtc aatttttccc catgtgtctg taaatcaaat agagtgggaa
     5761 gagtcataat caaactagcc ataccagcta aaaaggagat aactatgaaa tcaagaacag
     5821 atgattttcg agtcttaaag tcccacgaaa tttgacagag ataccagaaa ataagaaaca
     5881 atactgtcat atatccaaaa taataatttt gaataaataa gattgacaga cttgtaaagt
     5941 acaataggag tttcttttca gttatcagta gatgtaaacc agttataatt aaaggaatca
     6001 agataaaaac atctagccag gtttttatct ctaattgact gacagtgaaa ctcatcagag
     6061 cataggaagt agataaggct agttttaaaa tctgagggat agattgaaac aatttattca
     6121 aactaaaaaa ggttgacaga ccaatcaatc caaattttaa gagagttgtc agatagatag
     6181 catctggcat attcgttaga tcaaaaaagt aaaccagagg cgcgagaaaa ctacccaagt
     6241 aataactaga tagggcatag aagtttagcc ctagaccact tgtaaaggtg taaaacagat
     6301 tactatttcc atgtaggata tttcgtaagg ctacatcaaa aataacgtat tgatgaaagc
     6361 catctcctaa tagaggagag ttgtcgctat tccagtagat actttgagat agatatactc
     6421 cagacataat cactacagga atgatgaaag aaataaaata ggttcgatat gtttttaaaa
     6481 atgatttcat gttacctcgt agaatgatag aaaactcagt tggttaaccc aactgagttt
     6541 tgaagtttta tttagtcttt ccaaagttct ttaacttttg cttgtacttc tgcattttct
     6601 aggaattcat cgtaggtttc atcgatacgg tcaatgacgc catttttaga taagacaatg
     6661 atatggttag ccaaagtttg aataaattcg tggtcatggc tggcaaagat gattgattct
     6721 ttaaagtttt tcaatccatc attcaagctt gagatagatt ccaagtccaa gtgatttgtt
     6781 ggatcatcaa gtacaaggac atttgatttt aagagcatga gttttgaaag catgacacga
     6841 actttttctc cccctgacaa gacatttaca ggtttgttaa cttcatctcc agagaagagc
     6901 atacggccga ggaagccacg taggaaagta ttgtcatctt cttctttact tgcgaattga
     6961 cgcaaccagt caagaattga ttctcctcct gcaaaatcag ctgagttatc ttttggtagg
     7021 taagattgac tagttgtaac tccccacttg acagttcctt catagtcaat atctcccatg
     7081 attgcacgaa ttaatgcagt cgtttgaata tcattttgtc caataagtgc tgtcttatca
     7141 tctggacgca agatgaaact aatattatcc aagatagttt caccatcaat ctttacagtt
     7201 aaattttcta ctgtcaagag atcattacca atctcacgtt ccgctttaaa gttgataaat
     7261 ggatatttac gactagatgg cacaatctct tctagctcaa tcttatcaag cattttctta
     7321 cgtgatgttg cctgccttga cttagaagca ttggcagaga aacgagcaac aaattcttgc
     7381 aattgtttaa ttttttcttc tgctttagca ttacggtctg ctagcaattt agcagcaagc
     7441 tcagaagatt ccttccagaa gtcgtagttt ccgacataga gtttgatttt tccaaagtca
     7501 aggtcggcca tgtgagtaca aactttgttt aagaagtgac ggtcgtggga tactacgata
     7561 actgtgttat caaagtcaat caagaagtct tctaaccaag taatcgattg gatatccaaa
     7621 ccgttagtag gctcgtccaa gagaagaaca tctggtttac caaaaagtgc tttggcgagg
     7681 agaaccttta ctttttcacc gttggccaat tcgctcatgt tttggtagtg taattcttct
     7741 ggaatgttta ggttttgaag tagttgagag gcttcactct ctgcttccca acctccaagt
     7801 tcggcaaact ctccttcgag ttcggcagca cgaaccccgt cctcgtctga gaaatcttcc
     7861 ttcatgtaga tagcatcttt ctctttcatg atgctataaa gtttttcatt tcccatgata
     7921 acgacatcaa tggcacgttc atcttcgtag tcaaagtgat tttgacgaag aacagagaga
     7981 cgttcatctg gaccaagaga gatgtgacca gtagtaggtt cgatatctcc agctaaaatt
     8041 tttaaaaagg ttgattttcc ggcaccatta gcaccgatta atccgtaagt atttccttct
     8101 gtaaatttga tattgacatc atcaaaaagt ttgcgatcac taaaacgtag tgaaacatca
     8161 gatactgtaa gcaatgtttt tctcctatat gtgtaatata tttattctac tagaaaatac
     8221 agaaatattc aaatttttat ttgtcaattt tgtgtaaatt atatttacag tatcctttac
     8281 acaaatctgt aaaaagcaag gctgatttat tttgataaat tacggttatt tcattaaaaa
     8341 aatgctataa ttgaaaggac tatatcgaag gagaacaaaa tgactaaacc cattatttta
     8401 acaggagacc gtccaacagg aaaattgcat attggacatt atgttggaag tctcaaaaat
     8461 cgagtattat tacaggaaga ggataagtat gatatgtttg tgttcttggc tgaccaacaa
     8521 gccttgacag atcatgccaa agatcctcaa accattgtag agtctatcgg aaatgtggct
     8581 ttggattatc ttgcagttgg attggatcca aataagtcaa ctatttttat tcaaagccag
     8641 attccagagt tggctgagtt gtctatgtat tatatgaatc tagtttcgtt agcacgtttg
     8701 gagcgaaatc caacagtcaa gacagagatt tctcagaaag gatttggaga aagcattccg
     8761 acaggattct tggtctatcc aatcgctcaa gcagctgata tcacagcttt caaggctaat
     8821 tatgttcctg ttgggacaga tcagaaacca atgattgagc aaactcgtga aattgttcgt
     8881 tcttttaaca atgcatataa ctgtgatgtc ttggtagagc cggaaggtat ttatccagaa
     8941 aatgagagag cagggcgttt gcctggttta gatggaaatg ctaaaatgtc taaatcacta
     9001 aataatggta tttatttagc tgatgatgcg gatactttgc gtaaaaaagt aatgagtatg
     9061 tatacagatc cagatcatat ccgcgttgag gatccaggta agattgaggg aaatatggtt
     9121 ttccattatc tagatgtttt tggtcgtcca gaagatgctc aagaaattgc tgatatgaaa
     9181 gaacgttatc aacgaggtgg tcttggtgat gtgaagacca agcgttatct acttgaaata
     9241 ttagaacgtg aactgggtcc tattcgtgag cgccgtattg aatttgctaa ggatatggga
     9301 gaagtttata atatgattca aaaaggtagt gaaagagcgc gtgaagttgc gggtcaaacc
     9361 ctatctgagg taaaaggggc aatgggactt cattacttta actaagttta ttttacaaga
     9421 aactatcttt tctatctcga agaaaagata gttttttatt tacccctgta acatttgaca
     9481 aatttttata gaatggtatg atagatacaa tataaaaaga gtcaagctca aaaagaaaga
     9541 aaagaggaaa cttcgaatgt ctaattggga cactaaattt ttgaaaaaag gttttacctt
     9601 tgatgatgta ttgcttattc cagctgaaag tcatgtgttg cctaacgatg cagatttaac
     9661 aactaaattg gcagataatt tgactttaaa tatcccaatt attaccgctg ccatggacac
     9721 agttacagag agtcaaatgg ccattgctat tgctcgtgca ggcggtctcg gagttatcca
     9781 taaaaacatg tcaattgctc aacaagcaga cgaggttcgt aaggtaaaac gttctgaaaa
     9841 tggagttatt attgatccgt tcttcttgac gcctgaacat acaattgctg aagcagatga
     9901 gcttatgggt cgttaccgca tcagtggtgt tccagttgtt gaaacacttg aaaatcgtaa
     9961 attggttggt attttgacaa accgagatct tcgttttatt tcagattata atcaaccaat
    10021 ttcaaaccat atgactagtg aaaatcttgt tactgctcct gtgggtacgg atcttgcaac
    10081 ggctgagagt attcttcaag agcatcgtat tgaaaaactt ccgttggtcg atgaagaagg
    10141 cagtctttct ggtttgatca ctatcaaaga tattgaaaaa gttattgagt ttccaaatgc
    10201 ggctaaagat gagtttggtc gtcttctagt tgcaggtgca gtaggtgtta cttcagatac
    10261 atttgaacgt gcagaggctc tttttgaggc aggagcggat gcgattgtta ttgatactgc
    10321 acatggtcat tctgcaggtg tcttgcgtaa aattgccgag attcgtgctc atttcccaga
    10381 tcggactttg attgctggaa atattgctac tgctgaaggt gcacgtgccc tttatgaagc
    10441 gggtgtagac gttgttaagg ttggtattgg accaggttct atctgtacta ctcgtgtgat
    10501 tgctggtgtt ggtgttccgc aagtaacagc tatctacgat gctgcagctg ttgcgcgcga
    10561 atatggtaaa acgattattg ctgacggtgg gatcaagtat tctggagata ttgtaaaagc
    10621 acttgctgca ggtggaaatg ctgttatgct tggatctatg tttgctggaa ctgatgaagc
    10681 tccaggcgaa actgaaatct tccaaggacg taaattcaag acttaccgtg gtatgggatc
    10741 aattgctgct atgaagaaag gttcaagcga ccgttatttc caaggttctg tcaatgaagc
    10801 aaacaagctt gttccagaag gaattgaagg tcgtgttgct tataaaggag cggcagctga
    10861 tattgttttc caaatgattg gtggtattcg ctctggtatg ggttactgtg gtgcagctaa
    10921 ccttaaagaa ctacacgata atgctcaatt tattgaaatg tctggtgctg gtttgaaaga
    10981 aagccatcct catgatgtgc aaattactaa tgaggcacca aattattcta tgtaaaaaac
    11041 aatgaaaaga actccagtga aaacaggagt tcttttacaa tgttgtcaat ttccatttac
    11101 agcagcttta ccatcctgaa tagtgaagat acttagattt tctggcagat tttgaagatg
    11161 gtctaagctt gttgttgtga taaaggtttg gattgattga gaaatcgttt ctaataattt
    11221 taactgtcta gtgttgtcaa gttcactcat cacatcgtca agcagtaata taggagattc
    11281 tgtggtaatg ctttccatta attcgatttc tgctaatttt atcgagagga cgagactacg
    11341 atgttgacct tggcttccga aactagcatc catcccattt atataaaaag aaatgtcatc
    11401 tcgatgagga ccgacaccag tattcttttt aaataaatct ctggatctac ttttttctaa
    11461 agcaattttg aaagattcgg ataagttttg tttgtcagtt atattgacag aagattgata
    11521 ggatattgac aactcttcga tctgattaga gagttcaaaa tgtttcttac gcccaaatga
    11581 ttctagtttt tttatgaaat ctaagcggtg attcattaca cgacatccat aatcaactag
    11641 ctgatcatct aacacagaaa ggaatgtttc atctattttt tgagctgatt ttaggtaagt
    11701 gtttctttgc tttaggatgt ggttataatt ggttaagtca gataaataga ttggcttaat
    11761 ttgcccaagt tccatatcaa tgaattttcg tcgaatcgaa ggtgctcctt taattagttg
    11821 taaatcttca ggagcaaata agacaacatt catgtgtcct acataatctg aaaggcgtgc
    11881 ctgttttaag tgattaactt ttgttacacg acctttttgt gttagttcga tttctagggg
    11941 aatggatcca gtttttttct gaacgagacc tgaaagatga agttgttcct catcaaaatg
    12001 aatgagattt ttatctgttc gagttcgatg actacgcgtt aaggctaaaa aatagatagc
    12061 ctctaacatg tttgtttttc cttgtgcatt acgtcccaaa aagacattca atttaggatt
    12121 aaagtctatt ttcgtttctt tgtaattacg aaaagtcttg agagatagat gttgtagcca
    12181 catgattatc taccagggaa tcgtggagct tgttggcttt taggtgatga agcaggtttc
    12241 gatttgtctt ttttaactcc cttattcatc tttttgacaa gtttagcgat ccgttctttt
    12301 tcaactttat cagcttggta ttcatcttgt tcttcagaag taggttgtgt caacaagatg
    12361 tcaatgttca tgtcagggat gtcaacttta tcgccaatac gaagtttttt tccacgacgg
    12421 ctctctaatt ccctattaaa gtaaacagaa tgttcagaga gaaatgattt aatagctcct
    12481 ccgctatgtg taattccaag ttctttgaat agtgcttgga gggtaataaa ttcttcaaat
    12541 aatttgtatt ccataattca cctcaatctt tggtattata ccatattttc ctaaaaatag
    12601 tgagagagac agcgagaaat gtaagcgatt tttatttcaa aagtgttaca gggaacaaga
    12661 aaatttcagg ttttcgtgat ataatagaag tctgtatata aggaggtaaa tcatggagtt
    12721 agtgcatgga atttcaacac attttatcca atcaaaaaag tttaaaacaa acaaaattac
    12781 cgtgcgtttt accgctccat tatcccttga tacgattgca ggtcacatgt tgagtgcaag
    12841 tatgctagag actgctaatc agatgtaccc cacttctcaa gatttgagga gacacttggc
    12901 cagtctatac ggtacagata tgtcaaccaa ttgtttcaga agagggcaaa gccacattat
    12961 agaattgaca tttacctatg ttcgtgatga gtttttaagt aggaaaaacg tgctaacctc
    13021 tcagattttg gaacttgtaa aagaaactct tttttcaccc gtagtagttg ataatgggtt
    13081 tgatccggcc ttatttgaaa ttgagaaaaa acaattgcta gcaagtttag cagctgatat
    13141 ggatgattct ttttattttg cacataaaga attggataaa ttgttttttc atgatgaacg
    13201 tcttcaattg gaatatagtg atttacgaaa tcgtatttta gctgaaactc cacaaagttc
    13261 ttattcttgt ttccaagaat ttttagccaa tgatcgaata gatttctttt tcctaggtga
    13321 ttttaatgag gttgaaattc aaaatgtatt agaatcattt ggctttaaag gtcgaaaagg
    13381 agatgtgaag gttcagtatt gtcaacctta ttctaatatc cttcaggaag gtatggttcg
    13441 gaaaaatgtg ggacaatcca ttttggaatt aggttatcat tactgttcta aatatggtga
    13501 tgagcaacat ttacccatga ttgtaatgaa tggtttactt ggtggatttg ctcactctaa
    13561 gctctttaca aatgtccgtg aaaatgctgg attagcttat accatttcaa gtgagcttga
    13621 tttatttagt ggattcttga ggatgtatgc tggtatcaat cgagaaaatc gtaaccaggc
    13681 tcgtaaaatg atgaataatc aactgcttga tttaaaaaaa ggttatttta cagagtttga
    13741 gttaaatcag accaaggaaa tgattcgttg gtcgttgtta ctttctcaag ataatcaatc
    13801 ttcattgatt gaacgtgctt atcaaaatgc cttatttgga aaatcttcag cagactttaa
    13861 aagttggatt gcaaagcttg aacaaattga caaagatgct atttgtagag tagctaataa
    13921 tgtgaaacta caagcgattt actttatgga aggaatagaa tgacaaaggt tgtttttgaa
    13981 gaaaaatact atccagctgt aaaagaaatg gtttatcgaa ctcgtttggc caacggattg
    14041 acagttgctc ttttgcctaa aaaggaattt aaagaggttt acgggagtgt cactgtacag
    14101 tttggttcgg tagatacgtt tgtcacagaa gttgacggag atgtaaaaca atatcctgga
    14161 ggaattgctc attttcttga acataaatta tttgagagag aagattctag tgatttgatg
    14221 tcggctttta cgagtctagg tgcagatagt aatgccttta caagctttac aaaaacaaac
    14281 tatctttttt cagcaacgga ttatttttta gaaaatttag atttacttga tgaattggta
    14341 acatcagcac actttactga agcttccatt ctgacagagc aggatattat tcagcaagaa
    14401 cgagaaatgt accaagatga tccagattcg tgtttattct tttcaacttt agcgaatttg
    14461 tatcctggta cacctttagc aactgatata gttggaagtg aggagtccat ttcccaaatc
    14521 aatctaacta atttgcaaga aaattttaca aagttttaca aacctgtaaa catgtctctg
    14581 tttttagttg gtaattttga tgtggagcga gtacaggact attttgaaag caaagaactg
    14641 aaagattcag attttcagga agtagcaaga gaaaagttgt ttttacagcc tgtaaagcca
    14701 acagatagta tgagaatgga agtatcttct cccaaactag cgattggagt tagaggtaag
    14761 cgagaagttt ctgaagcgga ttgctatcga catcatattt tattaaaatt attgtttgca
    14821 atgatgtttg gttggacttc ggatcgtttt caaaaatgtt atgaatcagg taaaattgat
    14881 gcgtccttat ctctggaagt tgaaataaca agtcgctttc attttgtcat gttgacaatg
    14941 gatacgaaag agccagttgc tttgtctcat caatttagga aggctattcg taattttaca
    15001 aaggatttag atattacaga ggaacattta gatattatca aaagagagat gtttggcgaa
    15061 tttttcagta gcatgaactc tcttgaattt attgcaacgc aatatgatgc ttttgaaaat
    15121 ggtgagataa tttttgattt gccgaaaatt ttacaggaaa ttactttaga ggatgtcctt
    15181 gatgctggac atcatttaat agatgatggt gacatagttg attttacaat attcccatcg
    15241 tagtaaccta ttataataga cactagaaag aagggatgac aagtatgaga aaaaaaacaa
    15301 ttggagaggt tttacgatta gctagaatca atcagggatt gagtttagat gaattgcaga
    15361 aaaagacaga aatccagtta gatatgttgg aagcaatgga agcagacgat ttcgatcaac
    15421 ttccaagtcc tttttacacg cgttctttct tgaaaaaata tgcatgggct gttgagttag
    15481 atgaccaaat tgttttggat gcttatgatt ctgggagtat gattacttat gaggaagtag
    15541 atgttgatga agatgagttg acaggtcgta gacgttcaag taagaaaaag aagaaaaaaa
    15601 catcattttt acctttattt tattttatcc tttttgcttt atcgatttta atttttgtga
    15661 cttattatgt ttggaactat attcaaactc aaccagagga gccttctctt tctaattaca
    15721 gtgtggttca atcaacaagt tcaactagct ctgttcccca ctcctcaagt agtagttctt
    15781 ctagtataga atcagctata agtgtatcag gcgaaggaaa tcatgtagaa atcgcttata
    15841 agacaagtaa ggaaacagtt aaattgcaat tggcagtttc agatgttaca agttgggtca
    15901 gtgtttcaga aagcgaactt gagggcggtg taaccttatc gccaaagaag aaaagtgcag
    15961 aagcaacagt tgcaactaaa agtcctgtaa caattacgtt aggtgttgta aaaggtgttg
    16021 atttgacagt agataatcag actgttgatt tatcgaaatt aacagctcag actggacaaa
    16081 tcactgtaac ctttactaaa aattaaggaa aaacgaatga aaaaagaaca aattcccaat
    16141 ctcttaacaa taggtcgaat tctctttata cctattttta tctttatttt aacgatagga
    16201 aattcgatag agagtcatat agttgcagct attatctttg ctgttgccag tattaccgac
    16261 tatttagatg gatatttagc tcgtaaatgg aatgtggtca gtaattttgg taaatttgca
    16321 gatcctatgg cggataagtt actagttatg tcggctttta ttatgttgat tgagttaggt
    16381 atggctccgg cttggattgt tgcagtgatt atctgtcgtg agttagctgt gacaggttta
    16441 aggcttttat tggttgaaac tggtggaaca attttagcag cagcaatgcc tggaaaaatt
    16501 aaaactttta gtcagatgtt tgccattatt ttcttgctat tacattggac tttgcttggt
    16561 caagttctac tttatgtagc cttatttttc actatctact ctggctatga ctatttcaag
    16621 ggtagtgcct atgtatttaa agggacattt ggttcgaaat gaaatcaata attgatgtaa
    16681 aaaatctttc ttttcgctat aaagaaaatc agaactacta cgatgtgaag gatattacgt
    16741 ttcacgtgaa acgtggagaa tggctttcga ttgtagggca taatggtagt ggtaaatcaa
    16801 cgacggttcg attaattgat ggcttactgg aagcagaatc cggagagatt gtaattgatg
    16861 gccaacgttt gactgaggaa aatgtttgga atatacgtcg tcaaatcggt atggtttttc
    16921 aaaatccaga caatcaattt gttggagcga ctgttgaaga tgatgttgct tttggtttgg
    16981 aaaatcaggg actttctcgt caagaaatga aaaagagagt ggaagaagct ctggctttag
    17041 ttggcatgtt ggactttaaa aagagagagc cagcgcgtct atcaggtggc caaaagcaac
    17101 gtgtggccat tgcaggtgtt gtagccctaa gaccagctat tttaatctta gatgaagcaa
    17161 cgagtatgtt ggatcctgag gggcgtagag aacttattgg gacagtaaaa ggaattcgaa
    17221 aagactatga tatgacggtc atttctatta cccatgattt ggaagaagtc gccatgagtg
    17281 atcgcgtatt ggtcatgaaa aaaggggaaa ttgaatcaac tagtagtcca agggagcttt
    17341 tctctcgaaa tgatttagat caaattggat tagacgatcc ttttgctaat caattaaaaa
    17401 aatctttgag ccagaatggc tatgatttac ctgaaaatta tttgacagaa agtgagctag
    17461 aggataagct atgggaattg ctctagaaaa tgtgaatttt acatatcaag aaggtactcc
    17521 cttagcttca gcagctttgt cggatgtttc tttgacgatt gaagatggct cttatacagc
    17581 tttaattggg cacacaggta gtggtaaatc aactatttta caactcttaa atggtttatt
    17641 ggtgccaagt caagggagtg tgagggtttt tgatacctta atcacctcga cttctaaaaa
    17701 taaagatatt cgtcaaatta gaaaacaggt tggcttggta tttcagtttg ctgaaaatca
    17761 gatttttgaa gaaacggttt tgaaggacgt tgcttttgga ccgcaaaatt ttggagtttc
    17821 tgaagaagat gctgtgaaga ctgcgcgtga gaaactggct ctggttggaa ttgatgaatc
    17881 actttttgat cgtagtccgt ttgagctgtc agggggacaa atgagacgtg ttgccattgc
    17941 aggcatactt gccatggagc cagctatatt agtcttagat gagccaacag ctggtctaga
    18001 tcctctaggg agaaaagagt tgatgaccct gttcaaaaaa ctccaccagt cagggatgac
    18061 catcgtcttg gtaacgcatt tgatggatga tgttgctgaa tatgcgaatc aagtctatgt
    18121 aatggaaaag ggacgtttag taaagggggg caaaccaagt gatgtctttc aagacgttgt
    18181 ttttatggaa gaagttcagt tgggagtacc taaaattacg gccttttgta aacgattggc
    18241 tgatagaggc gtgtcattta aacgattacc gattaagata gaggagttca aggagtcgct
    18301 aaatggatag tatgatttta gggcgttata tcccagggga ttcgattgtt caccgattgg
    18361 atccacgtag caaattgctt gctatgatgc tactgatttt gattgtgttt tgggctaata
    18421 accccttgac gaatctgatt ctttttatag cgacagggat atttattgcc ttgtcaggag
    18481 tatctctttc attttttatt cagggcttga agtctatgtt tttcttgatt gccttcacaa
    18541 ctatttttca actatttttc atttctaatg ggaatgtttt atttgagttt tcgtttgtga
    18601 gaatcacgga ttatgctttg caacaagctg ggattatttt ttgtcgcttt gtattgatta
    18661 ttttcttttc aactttgtta accttaacaa ccatgccttt aagtttggca tcagctgtcg
    18721 aagctttatt agcaccttta aagcgtgtga aagttccagt tcatgaaatt ggattgatgc
    18781 tgtctatgag tttgcgtttt gtcccaacct tgatggatga tacgactcgg attatgaatg
    18841 cacagaaagc tcgtggagtg gattttggag aaggaagcat cgttcaaaaa gtaaaggcga
    18901 tgattcccat tttgattcct ctttttgcga caagtttaaa acgtgcagat tccttggcta
    18961 tcgctatgga agcgcgtggc tatcagggtg gaaaaggcag aagtcaatac cgacaattga
    19021 aatggactct aaaggatacg ctgaccattc ttgttattct cgtacttggt tgttgtttat
    19081 ttttcttaaa atcttagtag ctttcaggaa ttgataaaaa gttactgtaa cagtttttga
    19141 tataaaggta gggatatgaa ccgttttaaa aaatcaaaat atgtcattat tgtttttgtc
    19201 actgttctgc ttgtgtcagc tctcttagcg acgacttatt caagtacaat tgtgacaaaa
    19261 ttaggagatg gaatctcatt ggttgataga gttgtacaaa aaccttttca gtggtttgat
    19321 tctgtcaaat cagatttggc tcatttgaca cgaacatata atgaaaatga aagtttgaag
    19381 aaacagcttt accaattaga agttaaatca aatgaggtgg aaagtttaaa gacagaaaat
    19441 gaacaactgc gccaattgct tgatatgaag tctaaattgc aagccacaaa gactttagca
    19501 gcagatgtta ttatgcgttc tccggtatct tggaagcagg agttgacctt agatgcaggt
    19561 agatcaaaag gtgcttctga gaacatgtta gctattgcaa atggtggctt gattgggagt
    19621 gtttcaaaag tagaggagaa ctctactata gtcaaccttc tgacaaatac ggaaaatgct
    19681 gataagattt ctgttaaaat tcaacatggc tctactacaa tttatggaat tattattggc
    19741 tatgacaagg aaaatgacgt tcttaaaatt agccaattaa atagtaatag cgatattagt
    19801 gcgggagata aggtgactac tggtggatta ggaaacttta acgttgctga tattcctgtt
    19861 ggtgaagtgg ttgccacaac gcatagtaca gactatttga cacgagaagt aactgttaaa
    19921 ttgagtgcag atactcataa tgtagatgtg atagaattag tggggaattc ataatgagac
    19981 agttgaagcg agttggagta tttttattgc ttcctttctt tgttctaatt gacgcccata
    20041 ttagccagct tctgggctca tttttccccc atgtacattt ggctagtcat tttctttttc
    20101 tatttctctt atttgagacg atagaagtat cagagtatct ctacctagtc tattgttttg
    20161 ttataggctt ggtttatgat gtttactttt tccatctaat agggattaca actctcttat
    20221 ttatcttatt gggagccttc cttcataaat tgaatagtgt tattttgttg aatcgttgga
    20281 caagaatgct agctatgatt gtgctgacat tcctgtttga aatgggtagt tatcttttgg
    20341 cttttatggt agggttgaca gtagatagca tgtcgatttt tatagtctat agcttggtac
    20401 cgacgatgat tttaaatttt ttatggatta ctgtttttca atttattttt gaaaaatatt
    20461 atctataaga acgacatata aatgtaacaa aggcgtaata tttattaggc ctttttttgg
    20521 tatactagta ttgtctttaa aagaaggagt atctacgtaa tatgaagaaa aaaatcttag
    20581 cgtcactttt attaagtaca gtaatggttt ctcaagtagc tgttttaaca actgcgcatg
    20641 cagaaacgac tgatgacaaa attgctgctc aagataataa aattagtaac ttaacagcac
    20701 aacaacaaga agcccaaaaa caagttgacc aaattcagga gcaagtatca gctattcaag
    20761 ctgagcagtc taacttgcaa gctgaaaatg atagattaca agcagaatct aagaaactcg
    20821 agggtgagat tacagaactt tctaaaaaca ttgtttctcg taaccaatcg ttggaaaaac
    20881 aagctcgtag tgctcaaaca aatggagccg taactagcta tatcaatacc attgtaaact
    20941 caaaatcaat tacagaagct atttcacgtg ttgctgcaat gagtgaaatc gtatctgcaa
    21001 acaacaaaat gttagaacaa caaaaggcag ataaaaaagc tatttctgaa aaacaagtag
    21061 caaataatga tgctatcaat actgtaattg ctaatcaaca aaaattggct gatgatgctc
    21121 aagcattgac tacgaaacag gcagaactaa aagctgctga attaagtctt gctgctgaga
    21181 aagcgacagc tgaaggggaa aaagcaagtc tattagagca aaaagcagca gctgaggcag
    21241 aggctcgtgc agctgcggta gcagaagcag cttataaaga aaaacgagct agccaacaac
    21301 aatcagtact tgcttcagca aacactaact taacagctca agtgcaagca gtatctgaat
    21361 ctgcagcagc acctgtccgt gcaaaagttc gtccaacata cagtacaaac gcttcaagtt
    21421 atccaattgg agaatgtaca tggggagtaa aaacattggc accttgggct ggagactact
    21481 ggggtaatgg agcacagtgg gctacaagtg cagcagcagc aggtttccgt acaggttcaa
    21541 cacctcaagt tggagcaatt gcatgttgga atgatggtgg atatggtcac gtagcggttg
    21601 ttacagctgt tgaatcaaca acacgtatcc aagtatcaga atcaaattat gcaggtaatc
    21661 gtacaattgg aaatcaccgt ggatggttca atccaacaac aacttctgaa ggttttgtta
    21721 catatattta tgcagattaa tttacagagg gactcgaata gagccctctt ttcaggtttt
    21781 accgtgacaa tccctattaa aaattatatc aaaatagctt gaaaatattg gaaaagtatg
    21841 gtagaatgaa aattgtcgtg tgaacgataa tactcattct tgatgaattg tgaagcagtt
    21901 gcccttgggt cgttttgcga gttgaagtca agaagaggaa aaaaacaaaa aggagaaata
    21961 ctcatggcag taatttcaat gaaacaactt cttgaggctg gtgtacactt tggtcaccaa
    22021 actcgtcgct ggaatcctaa gatggctaag tacatcttta ctgaacgtaa cggaatccac
    22081 gttatcgact tgcaacaaac tgtaaaatac gctgaccaag catacgactt catgcgtgat
    22141 gcagcagcta acgatgcagt tgtattgttc gttggtacta agaaacaagc agctgatgca
    22201 gttgctgaag aagcagtacg ttcaggtcaa tacttcatca accaccgttg gttgggtgga
    22261 actcttacaa actggggaac aatccaaaaa cgtatcgctc gtttgaaaga aattaaacgt
    22321 atggaagaag atggaacttt cgaagttctt cctaagaaag aagttgcact tcttaacaaa
    22381 caacgtgcgc gtcttgaaaa attcttgggc ggtatcgaag atatgcctcg tatcccagat
    22441 gtgatgtacg tagttgaccc acataaagag caaatcgctg ttaaagaagc taaaaaattg
    22501 ggaatcccag ttgtagcgat ggttgacacc aatactgatc cagatgatat cgatgtaatc
    22561 atcccagcta acgatgacgc tatccgtgct gttaaattga tcacagctaa attggctgac
    22621 gctattatcg aaggacgtca aggtgaggat gcagtagcag ttgaagcaga atttgcagct
    22681 ttagaaactc aagcagattc aattgaagaa atcgttgaag ttgtagaagg cgacaacgct
    22741 taatttatac aaatagtaat tacctaggag ggcggggctt agcccggctc tcctattttc
    22801 aaaaaatata ggagaattaa aatggcagaa attacagcta aacttgtaaa agagttgcgt
    22861 gaaaaatctg gtgccggtgt tatggacgct aaaaaagcgc ttgtagaaac agacggtgac
    22921 atcgaaaaag cgattgaatt gcttcgtgaa aaaggtatgg ctaaggcagc taagaaagct
    22981 gaccgtgttg ctgcagaagg tttgactggt gtttatgtta acggtaatgt tgcagcagtt
    23041 attgaagtaa acgctgaaac tgacttcgtt gcaaaaaacg ctcaattcgt tgaattggta
    23101 aatactacag ctaaagtcat tgctgaagga aaacctgcta acaacgaaga agctcttgct
    23161 ttgataatgc cttcaggtga aactcttgaa gctgcatacg tatctgcaac agcaactatc
    23221 ggagagaaaa tctcattccg tcgctttgca ttgattgaaa aaacagacgc acaacacttt
    23281 ggagcatacc aacataacgg tggacgtatc ggtgttattt cagttgttga aggtggagac
    23341 gaagcacttg ctaaacaatt gtcaatgcac atcgcagcga tgaaaccaac agttctttct
    23401 tacaaagaat tggatgagca attcgttaaa gatgagttgg cacaattgaa tcacgttatc
    23461 gaccaagaca acgaaagccg tgcaatggtt aataaaccag ctcttccaca cttgaagtat
    23521 ggatcaaaag ctcaattaac tgatgatgtt attgctcaag ctgaagctga catcaaagct
    23581 gaattggctg cagaaggcaa accagaaaaa atctgggaca aaattattcc aggtaaaatg
    23641 gatcgcttca tgcttgataa cactaaagtt gaccaagctt acacacttct tgcacaagtt
    23701 tacatcatgg atgacagcaa gacagttgaa gcataccttg aatcagttaa cgcttcggta
    23761 gttgagtttg ctcgctttga agttggtgaa ggtatcgaga aagctgcaaa cgacttcgaa
    23821 gctgaagttg cagctacaat ggcagcagcc ttgaataact aataatagaa aggaagcaaa
    23881 ttgcttcctt ttttgtatag ggcttagatt tttcctgaaa ttgttttttc cccagtctca
    23941 ctcgattaga ataattaaaa caaaaagccc tataataagg gctaagtgca tttaggagac
    24001 tatacttcaa attcatagta agcgcgtcat aacaaggtat ctatcctaat tccccaactt
    24061 ccagtatacc agataaaaaa taattatcgg aggaaaggta ttgtactatg ataattcaac
    24121 taagtgattt aggtcaagtt caccttgttt gtggcaagac agatatgagg cagggaatag
    24181 actcattagc ctatgtagtt aaaacccact ttgaattgga tcctttctcc gatcaagtct
    24241 ttctcttttg tggtggacgt aaagaccgct ttaaagttct ttactgggat ggtcaaggat
    24301 tttggatatt atataaacgc tttgagaacg gaaaactgac ttggtccagt acagaaaagg
    24361 atgtcaaagc tctcgcacct gaacaagtag attggctgat gaagggcttt tctatcactc
    24421 cccaaatata gtggatttaa actagaatag tacacctctg cttctaaaac attgttagaa
    24481 atcgatttga ctatcctgtt cttatttcat tttactataa attcatcaga aagtcgtgat
    24541 ttctattgaa atgaggactt tctttttata ctcatctgtt ttcaaaaagc attctagtcc
    24601 gtctccgatt aacgatggac tttatcacct ccttctccag tccttgtatg acatcttcca
    24661 aagttcgaaa ggctttattc ttaaatccac gtttacgaat ttctttccac acttgttcaa
    24721 tggggttcat ctctggt
//
LOCUS       DAVFER010000028        24591 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1105170250
            SAMEA2167659-rid19724873.denovo.028, whole genome shotgun sequence.
ACCESSION   DAVFER010000028 DAVFER010000000
VERSION     DAVFER010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2167659
            Sequence Read Archive: ERR388902
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 24591)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24591)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928716.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928716.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 04:07:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,118
            CDSs (total)                      :: 2,073
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 120
            CDSs (without protein)            :: 120
            Pseudo Genes (ambiguous residues) :: 0 of 120
            Pseudo Genes (frameshifted)       :: 67 of 120
            Pseudo Genes (incomplete)         :: 47 of 120
            Pseudo Genes (internal stop)      :: 34 of 120
            Pseudo Genes (multiple problems)  :: 23 of 120
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24591
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2167659-rid19724873.denovo.028"
                     /strain="1105170250"
                     /db_xref="taxon:1313"
     gene            200..511
                     /locus_tag="VU534_001279"
     CDS             200..511
                     /locus_tag="VU534_001279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1513863.1"
                     /translation="MELKDFTEKEQEMIKKRLTMSNISDKETTEKILALVPQDLIKRI
                     PFFVRKHATTRTIKRISIEYPELYAVAQTSGEIPEKKREELRQIITTIFEQKMNKHSI
                     K"
     gene            515..1231
                     /locus_tag="VU534_001280"
     CDS             515..1231
                     /locus_tag="VU534_001280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEU1513864.1"
                     /translation="MKKYFIGGLGSNAYHSKDFLQELDSQVYFLNPYEKHLRDETELK
                     SWFKNEIVEEESICLIGHSLGGDLARYFASEFEEVKKLILLDGGYLDLDKILPLDTEL
                     EETKNYIKSQIVSDLDVLTSKEKSEAKHWSENMEKAVRQSYHWNVEYNRYELAINYEN
                     IEAILRLRRKIQAFKREVGDTLFISPRYPNEATWREEALKELPDYFDTIFLENFGHEL
                     YTQAPKEIASLMNEWLAYFL"
     gene            complement(1360..2175)
                     /locus_tag="VU534_001281"
     CDS             complement(1360..2175)
                     /locus_tag="VU534_001281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000617844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
                     /protein_id="HEU1513865.1"
                     /translation="MIRFLVLAGYFELTIYLHLSGKLNQYINMHYSYLAYISMVLSFI
                     LAIVQLYIWMKQVKTHSHLNSRLAKITSISLLAIPLVIGLTFPTVSLDSQTVSAKGYH
                     FPLSEGTDLAIQTSEGTTSQYLKPDTSSYFSKSAYEKEMRTAADKYLSQDSIQITNEN
                     YMEVMEAIYDYPDEFEGKTIQFTGFVYNDPSHANSQFLFRFGIIHCIADSGVYGLLTK
                     GNTRQYENNTWITAKGKLVNHYHKELKQNLPTLEIDSFTKVDKPENPYVYRAF"
     gene            complement(2172..3077)
                     /locus_tag="VU534_001282"
     CDS             complement(2172..3077)
                     /locus_tag="VU534_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HEU1513866.1"
                     /translation="MTAFQQLPSSVLQTGAIFLSIIIEALPFVLIGSIVSGLIEVYIT
                     PDKVYHFLPRNRWGRIFFGTFVGILFPSCECGIVPIINRFLEKKVPSYTAVPFLVTAP
                     VINPIVLFATYSAFGNSFHVALLRALGSILVAVILGIFLGFFWQEPIQKENRLACHEH
                     DFSYLSSAKKVFQVFVQAIDEFFDTGRYLVFGCLFASIIQVYVPTRILTSISATPLFA
                     ILLLMILAFLLSLCSEADAFIGASLLSSFGLAPVLAFLVIGPMLDIKNILMMKNYLKA
                     RFISHFITIVTLVVLVYSLLIGVIL"
     gene            3467..4786
                     /locus_tag="VU534_001283"
     CDS             3467..4786
                     /locus_tag="VU534_001283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000442116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1919 domain-containing protein"
                     /protein_id="HEU1513867.1"
                     /translation="MERQTLKDIEVIIVNQSTEEIASISQQMNLSFNIKIIDENSFAE
                     LSDMITGDYITFLSSNDSLFDWTFEKMYHAIKLSDSDVVLGHFADLVDGVFYFYPFWG
                     DNWLTENLTNVQVLQKMDDTDHRIRKQYRSLFGKLFNSKLLRKINQFDINNLIWRLYI
                     HSKTATYINFPTYIYKPVIDAKPLKDSYKIILENYENRIKDCAVLENYDIERAKKQYI
                     QELANFSAWLKNDGEYLDSDIVYHKLIAAEKGIFPFLELDRLDFTIISNNCVGGLIYK
                     QLGFQYRTPFVGLFILPDDYYKLTKHFRYYMEQELVFEEELISPSWTHEVYPLGHLGD
                     IDIHFLHYSSIEEARTKWEKRKKRINWNNLYFKFDNKDSASEEILNKMDNLPYSNKLI
                     LVNRPYKNLKSQCVIPGQEHLPELAIMSDPLNTFDIMAWLKKGGNAL"
     gene            4888..7017
                     /locus_tag="VU534_001284"
     CDS             4888..7017
                     /locus_tag="VU534_001284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding transcriptional accessory protein"
                     /protein_id="HEU1513868.1"
                     /translation="MDKKYEKISQDLGVTLKQIDTVLSLTAEGATIPFIARYRKDMTG
                     SLDEVAIKAIIDLDKSLTNLNDRKEAVLAKIQEQGKLTKELEEAILVAEKLADVEELY
                     LPYKEKRRTKATIAREAGLFPLARLILQNIVDLEKEAEKFVCEGFATGKEALTGAVDI
                     LVEALSEDVTLRSMTYQEVLRHSKLTSQAKDESLDEKQVFQIYYDFSETVGTMQGYRT
                     LALNRGEKLGVLKIGFEHATDRILAFFATRFKVKNAYIDEVVQQSVKKKVLPAIERRI
                     RTELTEKAEEGAIQLFSDNLRNLLLVAPLKGRVVLGFDPAFRTGAKLAVVDATGKMLT
                     TQVIYPVKPASARQIEEAKKDLADLIGQYGVEIIAIGNGTASRESEAFVAEVLKDFPE
                     VSYVIVNESGASVYSASELARQEFPDLTVEKRSAISIARRLQDPLAELVKIDPKSIGV
                     GQYQHDVSQKKLSESLDFVVDTVVNQVGVNVNTASPALLSHVAGLNKTISENIVKYRE
                     EEGKITSRAQIKKVPRLGAKAFEQAAGFLRIPESSNILDNTGVHPENYTAVKELFKRL
                     DIKDLNEEAQSKLKSLSVKEMAQELDLGPETLKDIIADLLKPGRDFRDSFDAPVLRQD
                     VLDIKDLVVGQKLEGVVRNVVDFGAFVDIGIHEDGLIHISHMSRKFIKHPSQVVAVGD
                     LVSVWVKKIDTEREKVNLSLLAPNETD"
     gene            7004..7453
                     /locus_tag="VU534_001285"
     CDS             7004..7453
                     /locus_tag="VU534_001285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000778579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HEU1513869.1"
                     /translation="MKLTDYVKQVSLEDFGRPFIHHVQWNRRLRSTGGRFFPKDGHLD
                     FNPKVYQELGLDVFRKIVRHELCHYHLYFQGKGYQHKDRDFKELLKAVDGLRFVPSLP
                     NSNSKPIKLYRCQSCQQRYQRKRRIDTQRYRCGLCRGKLLLVNQPED"
     gene            7511..7783
                     /locus_tag="VU534_001286"
     CDS             7511..7783
                     /locus_tag="VU534_001286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HEU1513870.1"
                     /translation="MNSKFYKMRRNRMISGVLAGLSDKWNFDVTLVRFLFAIFTVANF
                     GLGVIIYIILASIMPTKEEIEAEMYGTGPRKRKEAQAIDDNEGWFW"
     gene            complement(8137..8328)
                     /locus_tag="VU534_001287"
     CDS             complement(8137..8328)
                     /locus_tag="VU534_001287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000680763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1513871.1"
                     /translation="MKHKEHILIGLLYLLSPFIGQLLVEHTHFISTEFTGTAYVICWL
                     SVVISIHHFSKNVLSQQQK"
     gene            8756..9514
                     /locus_tag="VU534_001288"
     CDS             8756..9514
                     /locus_tag="VU534_001288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU1513872.1"
                     /translation="MTLLDVKHVQKIYKTRFQGNQVEALKDIHFTVEKGDYVAIMGES
                     GSGKSTLLNILAMLDKPSRGQVYLNGTDTATIKNSQASSFRREKLGFVFQDFNLLDTL
                     SVKDNILLPLVLSRRPITEMMKKLVVTAENLGINQLQEKYPYEISGGQKQRVAVARAI
                     ITEPEILLADEPTGALDSKSSAALLDVFNEINERGQTILMVTHSTAAASRAKRVLFIK
                     DGILYNQIYRGEKTERQMFQEISDTLTVMASEVN"
     gene            9516..11504
                     /locus_tag="VU534_001289"
     CDS             9516..11504
                     /locus_tag="VU534_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU1513873.1"
                     /translation="MFRLTNKLAVSNLIKNRKLYYPFALAVLLAVTITYLFYSLTFNP
                     KIAEIRGGTTIQATLGFGMFVVTLASAIIVLYANSFVMKNRSKELGIYGMLGLEKRHL
                     ISMTFKELVVFGILTVGAGIGIGALFDKLIFAFLLKLMKLKVELVATFQMNVVIAVLV
                     VFGLIFLGLMFLNALRIARMNALQLSREKASGEKRGRFLPLQTILGSISLGIGYYLAL
                     TVTDPLTALTTFFLAVLLVIFGTYLLFNAGITVFLQILKKNKKYYYQPNNLISVSNLI
                     FRMKKNAVGLATIAILSTMVLVTMSAATSIFNSAESFKKVLNPHDFGVSGQNVEKEDL
                     DKLLSQFASDKGYSVKEKEVLRYSNFGIANQEGTKLTIFEKGQNRVQPTTVFMVFDQK
                     DYENMTGQKLSLSGNEVGLFAKNDGLKGQKALTLNDHQFSVKEEFNKDFIVNHVPNKF
                     NILTTDYNYLVVPDLQAFLDQFPDSAIYNQFYGGMNVNVSEEEQLKVAEEYENYLNQF
                     NAQLDTEGSYVYGSNLADASSQMSALFGGVFFIGIFLSIIFMVGTVLVIYYKQISEGY
                     EDRERFIILQKVGLDQKQIKQTINKQVLTVFFLPLLFAFIHLAFAYHMLSLILKVIGV
                     LDTTMMLIVTLSICAIFLIAYVLIFMITSRSYRKIVQM"
     gene            complement(11546..12190)
                     /locus_tag="VU534_001290"
     CDS             complement(11546..12190)
                     /locus_tag="VU534_001290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000234620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VIT family protein"
                     /protein_id="HEU1513874.1"
                     /translation="MLRAGVLDANDGIISIAGVVIGVASATTNIWIIFLSGFTAILAG
                     AFSMAGGEYVSVSTPKDTEEAAVSREKLLLDQDRELAKKSLYAAYIQNGEFKTSAQLL
                     TNKIFLKNPLKALVEEKYGIEYEEFTNPWHAAISSFVAFFLRSLPPMLSVTIFPSDYR
                     IPATVLIVGVALLLTGYTSARLGKAPTKTAMIRNLAIGLLTMGVTFLLGQLFSI"
     gene            complement(12216..13211)
                     /locus_tag="VU534_001291"
     CDS             complement(12216..13211)
                     /locus_tag="VU534_001291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HEU1513875.1"
                     /translation="MQNHYTTKGEHLTIDSRRLIERWKKEGKSNREIASLLGKVPQTI
                     HTEIKRGTVRQCLGKGRFKEVYSADYAQQSYENNRKRSVKKSSLTKELKEKILHYHNQ
                     KFSPEMMVMAKGVNVGISTIYYWIHHGKLGLSKQDLLYPRKGKALKKQASTNFKPAGQ
                     SIEQRLEAINFRLENGHYEIDTVLLTRAKNYCLLVLTDRKSRHQIIRLIPNKSADVVN
                     QALKLILKQHKILSITADNGTEFNRLSNVFSEEHIYYAHPYASWERGTNENHNRLIRR
                     WLPKGTKKMTPKEVAFIEKWINNYPKKCLDYKSPREDFLMANLNLKFSVRNKSRN"
     gene            13918..15393
                     /locus_tag="VU534_001292"
     CDS             13918..15393
                     /locus_tag="VU534_001292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000661022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HEU1513876.1"
                     /translation="MKELDQNQAPIYEALVKLRKKRIVPFDVPGHKRGRGNPELVELL
                     GEKCVGIDVNSMKPLDNLGHPISIIRDAEELAADAFGASHAFLMIGGTTSSVQTMILA
                     TCKAGDKIILPRNVHKSAINALVLCGAIPIYIEMSVDPKIGIALGLENDRVAQAIKDH
                     PDAKAILINNPTYYGICSDLKGLTEMAHEAGMMVLVDEAHGAHLHFTDKLPISAMDAG
                     ADMAAVSMHKSGGSLTQSSILLIGEQMNSEYVRQIINLTQSTSASYLLMASLDISRRN
                     LALRGKESFEKVIELSEYARREINAIGGYYAYSKELIDGVSVCDFDVTKLSVYTQGIG
                     LTGIEVYDLLRDEYDIQIEFGDIGNILAYISIGDRIQDIERLVGALADIKRLYSRDGK
                     DLIAGEYIQPELVLSPQEAFYSERKSLTLDDSVGQVCGEFVMCYPPGIPILAPGERIT
                     REIVDYIQFAKERGCSLQGTEDPEVNHINVIKRKTNYKKSQ"
     gene            complement(15359..16075)
                     /locus_tag="VU534_001293"
     CDS             complement(15359..16075)
                     /locus_tag="VU534_001293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HEU1513877.1"
                     /translation="MLYVGIDVAKNKHDVTALNVPGKTVLKPLTFSNNKAGFELLDLS
                     LRQLNQDCLIALENTGHYAFNLLNFLHEQGYKVYTYNPLLIKKFAKSLSLRKTKTDKK
                     DAHGIALKLLSDPNREQFQHDNRQVELKILARHIHRLKKKQSDWKVQYTRCLDIIFPE
                     LDKIVGKHSEYTYQLLTRYPNPQKRLEAGFDKLIEIKRLTASNSRAFCRALKSSPNHQ
                     IEIRNSLDKTIDFSYSLSFS"
     gene            16331..17191
                     /gene="speE"
                     /locus_tag="VU534_001294"
     CDS             16331..17191
                     /gene="speE"
                     /locus_tag="VU534_001294"
                     /EC_number="2.5.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyamine aminopropyltransferase"
                     /protein_id="HEU1513878.1"
                     /translation="MDLWFSEVHTPDVKLSLRTAKQLYAGKSEWQDIEVLDTPAFGKI
                     LILNGHVLFSDADDFVYNEMTVHVPMAVHPNPKKVLVIGGGDGGVAQVLTLYPELEQI
                     DIVEPDEMLVEVCREYFPDFAAGLDDPRVTIYYQNGLRFLRNCEDDYDIIINDATDPF
                     GHTEGLFTKEFYGNSYRALKEDGIMIYQHGSPFFDEDESACRSMHRKVNQAFPISRVY
                     QAHIPTSPAGYWLFGFASKKYHPVKDFDKEGWKKRQLFTEYYTANLHVGAFMLPKYVE
                     DILEEEEGKK"
     gene            17188..18447
                     /locus_tag="VU534_001295"
     CDS             17188..18447
                     /locus_tag="VU534_001295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000088792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="saccharopine dehydrogenase family protein"
                     /protein_id="HEU1513879.1"
                     /translation="MSRLLVIGCGGVAQVAISKICQDSETFTEIMIASRTKSKCDDLK
                     AKLEGKTSTKIETAALDADKVEEVIALIESYKPEAVLNVALPYQDLTIMDACLATGVH
                     YIDTANYEAEDTEDPEWRAIYEKRCKELGFTAYFDYSWQWAYQEKFKEAGLTALLGSG
                     FDPGVTSVFSAYALKHYFDEIHYIDILDCNGGDHGYPFATNFNPEINLREVSAPGSYW
                     EDGKWVEVEAMSIKREYDFPQVGQKDMYLLHHEEIESLAKNIPGVKRIRFFMTFGQSY
                     LTHMKCLENVGLLRTDTINFNGQEIVPIQFLKALLPDPASLGPRTVGKTNIGCIFTGV
                     KDGVKKTIYIYNVCDHQECYAEVGSQAISYTTGVPAMIGTKLVMNGTWKQAGVYNLEE
                     LDPDPFMEALNEYGLPWVVVENPQMVD"
     gene            18447..19574
                     /gene="nspC"
                     /locus_tag="VU534_001296"
     CDS             18447..19574
                     /gene="nspC"
                     /locus_tag="VU534_001296"
                     /EC_number="4.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxynorspermidine decarboxylase"
                     /protein_id="HEU1513880.1"
                     /translation="MKLEQVPTPAYVIDLAKLEANCRILQYVQEEAGCKVLLAQKAYS
                     LYKTYPLISQYLSGTTASGLYEAKLAREEFPGEVHVFAPAFKDADLEELLEIMDHIVF
                     NSERQLRKHGPRCREAGVSVGLRLNPQCSTQGDHALYDPCAPGSRFGVTIDKIPSDLL
                     DLVDGLHFHTLCEQGADDLQTTLKAVEEQFGPYLHEVKWLNMGGGHHITREGYDVDLL
                     ISEIKRIRKTYNLEIYIEPGEAIALNAGYLATEVLDIVENGMEILVLDASATCHMPDV
                     LEMPYRPPLRNGFESQEKAHTYRLSSNTCLTGDVIGDYSFENPVQIGDRLYFQDMAIY
                     SFVKNNTFNGIGLPSLYLMDEQGDCSLLKAFGYQDFKGRLS"
     gene            19571..20656
                     /gene="aguA"
                     /locus_tag="VU534_001297"
     CDS             19571..20656
                     /gene="aguA"
                     /locus_tag="VU534_001297"
                     /EC_number="3.5.3.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="agmatine deiminase"
                     /protein_id="HEU1513881.1"
                     /translation="MMDSPKKLGYHMPAEYEPHHGTLMIWPTRPGSWPFQGKAAKRAF
                     TQIIETIAEGERVYLLVEQAYLSEAQSYLGDKVVYLDIPTNDAWARDTGPTILVNDKG
                     KKLAVDWAFNAWGGTYDGLYQDYEEDDQVASRFAEALERPVYDAKPFVLEGGAIHSDG
                     QGTILVTESCLLSPGRNPNLTKEEIENTLLESLGAEKVIWLPYGIYQDETNEHVDNVA
                     AFVGPAELVLAWTDDENDPQYAMSKADLELLEQETDAKGCHFTIHKLPIPAVRQVVTE
                     EDLPGYIYEEGEEKRYAGERLAASYVNFYIANKAVLVPQFEDVNDQVALDILSKCFPD
                     RKVVGIPARDILLGGGNIHCITQQIPE"
     gene            20666..21541
                     /gene="aguB"
                     /locus_tag="VU534_001298"
     CDS             20666..21541
                     /gene="aguB"
                     /locus_tag="VU534_001298"
                     /EC_number="3.5.1.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001246759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-carbamoylputrescine amidase"
                     /protein_id="HEU1513882.1"
                     /translation="MRNVRVATIQMQCAKDVATNIQTAERLVRQAAEQGAQIILLPEL
                     FEHPYFCQERQYDYYQYAQSVAENTAIQHFKVIAKELQVVLPISFYEKDGNVLYNSIA
                     VIDADGEVLGVYRKTHIPDDHYYQEKFYFTPGNTGFKVWNTRYAKIGIGICWDQWFPE
                     TARCLALNGAELLFYPTAIGSEPILDTDSCGHWQRTMQGHAAANIVPVIAANRYGLEE
                     VTPSEENGGQSSSLDFYGSSFMTDETGAILERAERQEEAVLLATYDLDKGASERLNWG
                     LFRDRRPEMYRQITD"
     gene            complement(21722..22531)
                     /locus_tag="VU534_001299"
     CDS             complement(21722..22531)
                     /locus_tag="VU534_001299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000593565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEU1513883.1"
                     /translation="MIKLLALDMDGTLLNEAKEIPQAHITAIHKAIEKGVKLVLCTGR
                     PLFGVLPYYKKLELDLQNEYIIVNNGCSTHQTSDWSLVDWKELSPADIEYLYDLAEKS
                     DVQLTLFDESHYFVLGDKPNQVIENDAKLVFSDLTEISLEEATSGKFRMFQGMFLGTK
                     EQTDDFEQRFAEELCQRFSGVRSQPVIYEAMPLGTTKATALSRLAEILKIDSSEIMAM
                     GDANNDIEMLQFAGLGIAMGNASDYIKSLADAVTSSNEEDGVARAIEKYIL"
     gene            22803..23024
                     /locus_tag="VU534_001300"
     CDS             22803..23024
                     /locus_tag="VU534_001300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000602450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_0924 family bacteriocin-like peptide"
                     /protein_id="HEU1513884.1"
                     /translation="MILMTKNINLTNEELELIQGGADPYGKNPNGRYDWEIEPVLTLL
                     VHGFCPRGTYDSGYIGGGNHLCKGSAARF"
     gene            23078..23749
                     /locus_tag="VU534_001301"
     CDS             23078..23749
                     /locus_tag="VU534_001301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU1513885.1"
                     /translation="MKKRAIQILLALSLIFYKSTWFWRLFNYLAKPYLPASREFFQIL
                     LLMESGVLFLAVIYLLVFAGKKIFHFKWQLRYFIYLLLGYIISYMSDFLFSYFISLSS
                     NQISLNETVEMMGRQEFPYFLLIVCFIAPIAEELIYRGVLMTTFFKNSPWYGDVLLSA
                     IIFGYIHINFALTPLAFFIYASGGLILALLYRMTKNLYYPILVHILINITAFWDVWLL
                     LFSGS"
     gene            complement(23801..23998)
                     /locus_tag="VU534_001302"
     CDS             complement(23801..23998)
                     /locus_tag="VU534_001302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU1513886.1"
                     /translation="MFIFYPQLLYLFIIPYFRSFPKRKKEHPILLNYLHYLPFSSQPY
                     FQNQFKKITGYTPLQYRKEKR"
     gene            23991..>24591
                     /locus_tag="VU534_001303"
     CDS             23991..>24591
                     /locus_tag="VU534_001303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001025716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEU1513887.1"
                     /translation="MNIQQLRYVVAIANSGTFREAAEKMYVSQPSLSISVRDLEKELG
                     FKIFRRTSSGTFLTRRGMEFYEKSQELVKGFDIFQNQYANPEEEKDEFSVASQHYDFL
                     PPTITAFSERYPDYKNFRIFESTTVQILDEVAQGHSEIGIIYLNNQNKKGIMQRVEKL
                     GLEVIELIPFHTHIYLREGHPLAQKEELVMEDLADLPTVR"
BASE COUNT         7459 a         4489 c         5193 g         7450 t
ORIGIN      
        1 accaacaaga cgtttaaatc gtgcatcagt tagttgttta cttgcttcat aattcataga
       61 actactatac catattttgt ttcgcaggaa gtctaatgct aaaatcttat cagtgagaag
      121 atttcttaaa gtttattctt tgtagtttca tctgtattag tacataattt aacttagaga
      181 aaataggagg actaatcgaa tggaattaaa agattttaca gaaaaagaac aggaaatgat
      241 taagaaaagg cttacaatgt ctaatattag tgacaaagaa actactgaga agattctggc
      301 gctagtccca caagacttga ttaagcgaat cccgtttttt gtcagaaaac atgctacaac
      361 acgtacgatt aaacgcattt caattgaata ccctgaactc tacgctgtag ctcaaacaag
      421 tggtgagatt ccagaaaaaa aacgcgaaga attgcgtcag attatcacaa ctatctttga
      481 acaaaagatg aataagcata gtattaagta gagaatgaaa aaatatttta ttggcggttt
      541 gggaagcaat gcctatcata gcaaggattt tcttcaagaa ctagattcgc aggtctattt
      601 tctaaatcca tatgaaaagc atcttcgaga tgaaacagaa ttgaaatcat ggtttaaaaa
      661 tgaaattgta gaggaagaat ctatctgtct gataggccat tctcttggag gagatttagc
      721 tcgttatttc gcatcggaat ttgaagaagt aaagaaactg attcttttgg atggtggcta
      781 tctagattta gataagattt tacctttgga tacagagtta gaggaaacta aaaattatat
      841 caaatctcaa attgtttcgg acttagatgt tcttacttct aaagaaaaat ctgaagcaaa
      901 gcattggtca gaaaatatgg agaaagctgt aagacagtct tatcactgga atgttgagta
      961 taatagatat gagttggcta taaattatga aaatatagaa gcgatactcc gcctacggag
     1021 aaaaatacaa gcttttaaga gagaagtggg agataccttg tttattagtc ctcgctatcc
     1081 taatgaagct acatggagag aggaagccct aaaagaattg ccagactatt ttgatactat
     1141 ttttttagaa aactttggcc atgagcttta tactcaagca cctaaagaaa tcgctagtct
     1201 aatgaatgag tggctcgctt attttctatg agctacttgt attgctggga atggtataag
     1261 atgaaaatct acaagtcact aattttcata taacaaaaaa cgaacaggct ctttttctgt
     1321 tattcagaag agaacttgtt cgtttttatc ttgattttct taaaaagctc tatatacata
     1381 gggattttct ggtttatcga ctttggtaaa gctgtcgatt tccaaggttg gaaggttttg
     1441 tttgagttct ttatggtagt gattgaccag ttttcctttg gctgttatcc aagtgttgtt
     1501 ttcatactgc cgggtattgc ccttggtcag caatccatag acaccagaat ctgcgataca
     1561 gtggataatg ccgaatcgga acagaaattg actattggca tgactggggt cgttatagac
     1621 aaagcctgta aactggattg tcttgccctc aaactcatct ggatagtcgt agatagcctc
     1681 catgacttcc atatagtttt cattagtgat ctgaatacta tcttgggata agtatttatc
     1741 cgccgccgtt cgcatttcct tttcataggc tgattttgaa aaataagaac tggtatctgg
     1801 tttcaaatat tggcttgtcg tcccttcgct tgtctgaatg gctagatccg ttccttccga
     1861 tagggggaaa tgataacctt tagcagaaac agtctgagaa tccaagctaa cagttgggaa
     1921 agttaagccg atgacaagtg gaatagccag aagagaaata ctcgttatct tggctaatcg
     1981 gctgttcaga tgactgtggg ttttgacttg cttcatccag atatacaatt gaacgatagc
     2041 caagataaaa gaaagcacca tggagatata ggccagatag gaatagtgca tgttgatgta
     2101 ctggtttagt ttgcccgaca gatggaggta aatagtcagt tcaaaatagc cagctaaaac
     2161 taaaaatcga atcataggat aactccaatc aagagagaat agactaagac gacaagagtt
     2221 acaattgtta tgaagtgact gataaatcgt gctttcaagt aatttttcat catgagaata
     2281 tttttgatat ccagcattgg accaatgacg agaaaggcca gaactggtgc caaaccgaaa
     2341 ctcgagagaa gagaagcacc tataaaggca tccgcctcac tacagagcga aagaagaaag
     2401 gctaaaatca tcaagagcag gatggcaaaa agaggggtcg cactgataga ggtcagaatc
     2461 cgagtcggaa cgtagacctg tattatagaa gcaaagaggc agccaaatac caaataacgc
     2521 cccgtatcaa aaaattcatc aatggcctgc acaaagactt gaaaaacttt ttttgcagaa
     2581 ctcaagtaag aaaaatcatg ctcatgacaa gccagacgat tttctttctg aatcggttct
     2641 tgccagaaaa atcctagaaa aattcctagt attacagcca caagaatgga acccagagct
     2701 cgtaataggg cgacatggaa ggagttgcca aaggcagaat aggtcgcaaa aagaacaatg
     2761 ggattgataa caggtgctgt cacaagaaaa ggaacggccg tgtaacttgg aacctttttt
     2821 tccagaaaac gattgatgat ggggacgatt ccacattcac aagaagggaa aagtataccg
     2881 acaaaggtcc caaaaaagat tctcccccaa cgatttcgag ggagaaaatg ataaaccttg
     2941 tcaggtgtga tataaacttc aatcagccct gagacaatgc ttcctatcag aacgaaggga
     3001 agggcttcaa tgataatgga gagaaaaatg gctccagttt gaagtacact agatgggagt
     3061 tgttgaaaag cagtcatcta gtttttcttt tctgctttga cttttttctc tttgtcatca
     3121 gggaaagtaa cttgtttcaa atcagggagt ttagcaaact cttcaaacat cttgtccaag
     3181 tcgtctcgtt ttgtaaattt gacagccata ggtgtacctc gattctagat tctacctcta
     3241 ttatactatt attttgcgga aaagggaaaa gttaaaattt caaattgagt agctaagaga
     3301 taatatagct tgatattacc tgatatatat cataattgtg ctataattaa ataaaaagaa
     3361 aatcattatc agaaaattat gggaggtagt caaactgact tactcaatta gtgttgtttt
     3421 gttacatcaa ggagataaaa atagtttatt agagtctttg tcaatagtgg agagacaaac
     3481 attaaaagat atagaagtta ttattgtaaa tcaatctaca gaggagatag cttccattag
     3541 ccaacagatg aatctatcat ttaatattaa gattatagat gagaattctt ttgctgagtt
     3601 gtctgatatg attacaggag attatattac gtttctatct tcaaatgatt cattatttga
     3661 ttggacattt gaaaagatgt atcatgcgat aaaattatcc gattctgatg ttgttcttgg
     3721 tcattttgct gatttggttg atggagtatt ttacttttat cctttttggg gggataattg
     3781 gttgacagaa aatttaacga atgttcaagt tttacaaaag atggatgata cagatcatcg
     3841 aattagaaaa caatatcgct cattatttgg aaaattattc aatagtaagc ttttacgaaa
     3901 aataaatcaa tttgatataa acaaccttat ttggagactt tatattcact ctaaaactgc
     3961 aacctatatt aatttcccga catatatcta taaacctgtt atagatgcta aacctctaaa
     4021 agactcctac aaaatcatat tagaaaatta tgaaaataga atcaaagatt gcgccgtctt
     4081 agaaaactat gatatagaaa gagcgaaaaa acaatatatt caagaattgg caaattttag
     4141 tgcttggtta aaaaatgacg gtgaatattt agattctgat attgtttatc ataagttaat
     4201 agctgcagag aaaggaattt tcccttttct tgagcttgat agattagatt ttacgattat
     4261 aagtaataat tgtgttggag gattaattta taaacagctt ggttttcaat atagaacacc
     4321 ttttgttggt ttatttattc ttcctgatga ttattataaa cttacaaagc attttcgtta
     4381 ttatatggaa caagaacttg ttttcgaaga ggaacttatt tcaccgagct ggactcatga
     4441 agtttatcct ttggggcact taggagatat agatattcat tttctacatt attctagtat
     4501 tgaagaagca cgaactaagt gggaaaaaag aaaaaaacgc ataaattgga ataatcttta
     4561 ttttaaattt gataataaag attcagctag tgaagaaatt ttaaataaga tggataatct
     4621 tccttattct aataaattaa ttttagtcaa tcgtccatat aaaaatttga aaagtcaatg
     4681 tgttattcca ggtcaggaac atcttccaga actggctatt atgtctgatc cattaaatac
     4741 ttttgatatc atggcttggt taaaaaaagg tggcaatgct ctttaagtgc aagttattgc
     4801 gctgtagcat ataaatctat ttcctacata ttttttaaat gttctacgag ttaatttgaa
     4861 acgtttagct tgtggtataa tagatttatg gataaaaaat atgaaaaaat ctctcaggat
     4921 ttgggagtga cgttaaagca aattgatacc gttctaagtt tgacagctga aggggcgact
     4981 attcccttta tcgcgcgtta tcgcaaggac atgactggta gtctggatga ggtggcgatt
     5041 aaggctatta ttgatttgga taaaagtctg acaaatctca atgaccgtaa ggaagctgtc
     5101 ttagctaaga ttcaagaaca aggtaagttg accaaggaat tggaagaagc tatcttagtt
     5161 gccgaaaaat tagcagacgt tgaagaactc tatcttcctt ataaggaaaa gcgtcgtacc
     5221 aaggcaacca ttgcccgtga agctggactc tttcctcttg ctcgcttgat tttgcagaat
     5281 atagttgact tagagaaaga agctgaaaag ttcgtctgtg aaggatttgc gactggcaag
     5341 gaagccttga ccggtgcagt tgatattttg gtcgaagcct tatcggaaga tgtgaccttg
     5401 cgttctatga cttatcagga agtgctgaga cactctaaac ttacttctca agccaaggat
     5461 gaaagtcttg atgaaaagca ggtttttcag atttattatg atttttcaga gacagttgga
     5521 actatgcaag gctatcgtac cttggctctc aatcgtgggg agaaacttgg tgtcttgaag
     5581 atcggttttg aacatgcgac ggaccgtatt cttgccttct ttgctactcg tttcaaggtg
     5641 aaaaatgctt atattgatga agttgttcag caatccgtta agaaaaaggt cttgcctgct
     5701 atcgagcgtc gtattcggac agaattaact gagaaagctg aagaaggagc tatccaactt
     5761 ttttctgaca atctgcgcaa tctcctcttg gttgctccac tgaaagggcg cgtggttctt
     5821 ggatttgacc cagcctttcg tacaggtgcc aagctagctg tcgtggatgc aacaggaaaa
     5881 atgctgacaa ctcaggttat ttatcctgtt aaaccagcat cagctcgtca aatcgaagaa
     5941 gccaagaaag atttagcaga tttaattggt caatacggtg tagagattat tgccattgga
     6001 aatggaacgg ccagtcgtga aagtgaagct tttgtagcgg aagttctgaa agatttccct
     6061 gaagtcagct atgttatcgt taatgaaagt ggtgcttctg tctattctgc cagcgaactt
     6121 gctcgtcagg agtttccaga cttgaccgtt gaaaaacgct ctgccatttc tatcgcccgt
     6181 cgtttgcaag atcctcttgc ggaattggtc aaaatcgatc ctaagtcaat tggtgtcggt
     6241 caataccaac acgatgtcag tcagaagaaa ctatctgaga gtctggactt tgttgtcgat
     6301 acagtggtta accaagttgg tgtcaatgtc aatacagcta gcccagctct tctttcacac
     6361 gtagctggac tcaacaaaac tatctctgaa aatattgtca aataccgcga ggaagaagga
     6421 aaaatcactt cacgcgccca aatcaagaaa gttcctcgtc tgggagccaa ggcctttgag
     6481 caggctgctg gtttccttcg tatccctgaa agtagcaata tccttgataa tacaggagtt
     6541 cacccagaga attacactgc agttaaggaa ctcttcaaac gtttagatat taaagaccta
     6601 aacgaagaag cccaaagcaa actcaagtcg ctttcagtca aggaaatggc gcaagagtta
     6661 gaccttggtc cagaaactct taaagatatc attgcagatc ttctcaaacc aggtcgagat
     6721 ttccgtgatt cctttgacgc acctgtgctt cgccaagatg tcctagatat caaggactta
     6781 gtggttggac aaaagctaga aggagtggtg cgtaacgttg ttgatttcgg tgcttttgtt
     6841 gatatcggaa ttcatgagga cggtctcatc catatttccc atatgagtcg caagtttatc
     6901 aaacacccta gtcaagtggt ggcagttgga gatttggtga gcgtttgggt taagaaaatt
     6961 gatactgaac gtgaaaaagt taatctgtct ctcctagctc caaatgaaac tgactgatta
     7021 cgtcaagcag gtttcactag aagacttcgg cagacctttt atccatcatg tccagtggaa
     7081 taggcgtcta cgttcgacag gtgggcgatt tttccccaaa gatgggcatt tggattttaa
     7141 tcccaaggtt tatcaggaac tggggttgga cgtttttagg aaaattgtcc gacatgaact
     7201 ctgtcattat cacctctatt ttcaagggaa aggctatcaa cacaaggatc gggattttaa
     7261 ggaactgttg aaagcagtgg atggattacg gtttgtacca tccttgccca atagtaactc
     7321 caagccaatc aagctctatc gttgccaatc ctgccagcaa aggtatcagc gtaagcgtag
     7381 gattgatacc caacgctatc gctgtggact ttgtcgagga aagttgctat tagtaaatca
     7441 gcctgaggac tgatgaaagc cgagcctatc cgtgatatac tagtctaacc tagcagaaag
     7501 aggaaatatc atgaacagta agttttataa aatgagacga aatcgcatga tttcaggagt
     7561 tttagcaggt ctgtcagaca agtggaactt tgatgttacc cttgtacgtt ttctgtttgc
     7621 catttttaca gtcgcaaact ttggacttgg ggtgattatc tatatcatcc tagcttctat
     7681 catgccaacc aaggaagaaa tcgaagcaga aatgtacgga acaggcccac gtaaacgcaa
     7741 agaagctcaa gccattgacg ataatgaagg ctggttttgg tgaggtttta caaaagattt
     7801 ggaatacgca aaaagcttta aatcaatagt ctaaactgct tgatttaaag cttttttact
     7861 tttatactca ataaaaatca aagtgcaaac taggaagcca gccgcaggct gtaatttagt
     7921 cggcaatgtg aagttgatat agtttgcact ttgatttttg aatagtatta ataatatttc
     7981 gccagcttca tccacaaact atagtggatt ggaactagaa taggacacct atacttctaa
     8041 aacattgtta gaaatcgatt tgactgtcct gatcgatttg tcctgttctt atttcatttt
     8101 actataaaag cagtaattta aacgcagttt tttaatctat ttttgctgtt gagacaatac
     8161 atttttggaa aaatggtgga tgctgataac aactgataac cagcaaataa cataagcagt
     8221 gccggtaaat tctgtactga taaagtgtgt gtgttcaact aagagctgac cgatgaatgg
     8281 agagagcaga tagagaagtc cgatgagtat atgttctttg tgtttcatta aagcgcacct
     8341 tctttcctta taggttgaac gacttgcaag tgttaaattg aatggtatgt tatctaggta
     8401 agcttactaa aatgttagtt cccgcttcct ccttttcaaa gtaagccttt tcacacttat
     8461 attttacaac tttaaaaata ggaaatcaaa tcattttcta agtaattttg cttatatttc
     8521 acccaatctt acaaaaatgt aagattaaag tctcttttgt aaggttaggt tatggcaagc
     8581 ggtctttttt tgatgtaaac tagactcata aagaacaaag gagtaacatc atgaaacaaa
     8641 tcttacataa gaaaactaga aaaccaagtc acaaagaaat tgagcgcgtt cagctgggat
     8701 gcactatgat gcaagctaca tttcatttga tgggatatta agaaaggaga ttttcatgac
     8761 acttttagat gtaaaacacg ttcaaaaaat ttataaaaca cgttttcagg gcaaccaagt
     8821 agaagccctc aaggatattc actttaccgt agaaaagggt gactacgttg ccatcatggg
     8881 tgagtctggt tctggtaaat caactcttct caatattcta gctatgttgg ataaaccaag
     8941 tcgtggtcag gtttacttga atggaactga caccgcaact attaaaaatt cacaggcttc
     9001 tagtttccgg cgtgaaaagc taggatttgt cttccaagac tttaacttgc tagatactct
     9061 gtctgttaag gacaatatct tgcttccgct tgtcttgtca agaagaccta taacggagat
     9121 gatgaagaaa ttggtggtga cagctgagaa tctgggtatt aaccaattgc aagagaagta
     9181 cccttacgag atttctggtg gtcagaaaca gcgtgtagca gtagcccgcg ccatcatcac
     9241 agaacctgaa attctccttg cggacgagcc aacaggagcc cttgattcca agtcatctgc
     9301 agccttactt gatgtcttta atgaaatcaa tgagcgtggg caaaccatcc tcatggtaac
     9361 ccactcaaca gcagctgcta gcagggccaa gcgtgttctc tttatcaaag acggcattct
     9421 ttacaaccaa atctaccgtg gagagaagac agagcgtcag atgttccaag aaatctctga
     9481 taccttgact gtcatggcaa gcgaggtgaa ttagtatgtt tcgattaacc aataagttag
     9541 cggtatcgaa cttgattaaa aaccgcaaac tctactatcc ctttgcactg gctgttctct
     9601 tggcagtcac catcacctat ctcttttact ccctaacctt caatccaaag attgcggaaa
     9661 tccgtggagg aaccaccatt caagcaacac ttggatttgg tatgtttgtc gttacccttg
     9721 cgtcagccat tatcgtcctc tatgccaata gttttgtcat gaaaaaccgt tccaaggaac
     9781 tgggtatata tggcatgtta ggcttggaga agcgccatct aatcagtatg acctttaagg
     9841 agttagtggt atttgggatt ctaactgttg gagcgggtat cggtattgga gccttgtttg
     9901 acaagttaat tttcgctttc ctgctcaaac taatgaaact gaaggttgag ctggttgcta
     9961 ccttccaaat gaatgttgtc attgcagtac ttgttgtctt tggattgatt ttcctaggcc
    10021 tcatgttcct gaatgctctt cgaatcgccc gtatgaatgc cctccagctc tcgcgtgaga
    10081 aagcaagcgg agagaaaaga ggtcgcttcc tacctctcca aacgattctt ggttccataa
    10141 gtttagggat tggctattat cttgccctta cggtaaccga tcctcttaca gccctaacaa
    10201 ctttcttcct agctgttttg ctggttatct ttggtactta tctattgttt aatgcaggga
    10261 ttacagtctt cctacaaatc ttaaagaaaa acaagaaata ctattaccaa cctaataacc
    10321 tcatatctgt ttccaacttg attttccgta tgaagaaaaa tgcggttgga ctagcaacca
    10381 tcgctatttt gtcaacaatg gttttggtaa ccatgtcagc agcgacaagc attttcaatt
    10441 ccgcagaaag ctttaaaaaa gttctaaatc ctcatgattt tggggtttca gggcaaaatg
    10501 ttgaaaaaga agatttggac aaactcttga gccagtttgc aagtgacaaa ggttatagtg
    10561 tcaaagagaa agaagtactt cgttacagta actttggtat tgcaaatcaa gaaggaacca
    10621 agttaactat ttttgaaaaa ggacaaaacc gtgtccaacc cacaacagtt ttcatggtat
    10681 ttgaccaaaa agattatgaa aatatgactg gtcaaaaact gtctctatca ggaaatgagg
    10741 tcggtctctt tgccaaaaat gacggactga aaggacagaa agctctaact ctaaatgatc
    10801 atcaattttc tgtcaaagaa gaatttaata aagatttcat tgtgaaccat gttccaaata
    10861 agtttaatat cttgactact gattacaatt accttgttgt tcctgattta caagcctttt
    10921 tggatcaatt cccagattcg gctatctata atcagtttta cggtggtatg aatgtaaatg
    10981 tcagtgaaga agaacaactc aaggtcgctg aggagtatga aaactacctc aatcaattta
    11041 atgctcaatt agacacagaa ggtagctatg tttatggtag caatctagca gatgctagtt
    11101 ctcagatgag tgccctcttt ggtggtgtct tctttatcgg tattttccta tccattatct
    11161 ttatggtcgg aactgttctg gtcatctact acaaacaaat ttctgaaggc tacgaagacc
    11221 gtgaacgctt tattatcttg cagaaagtcg gtttggacca aaagcaaatc aagcaaacca
    11281 tcaacaaaca ggttttaact gttttcttcc ttcctttgct ctttgccttc atacatctcg
    11341 cctttgccta ccatatgctt agcctgattt taaaagtgat tggtgtactg gatacgacta
    11401 tgatgttgat tgtgaccttg tctatctgcg ctatcttcct catcgcctat gtgctgattt
    11461 tcatgattac ttcaagaagt tatcgcaaga ttgtgcaaat gtaaaaaaga tacctcgact
    11521 tcaaaatcga ggtatttctt gtattctaaa tgctgaaaag ttgtccgagc aggaaggtaa
    11581 ctcccatggt caagagacca atagcaaggt tccgaatcat agctgttttg gttggggctt
    11641 ttccaagtct agcacttgtg taaccagtga gaagaagggc cacaccgaca ataaggacgg
    11701 tagcagggat gcggtaatca cttggaaaaa tggtcactga cagcattgga ggcaaacttc
    11761 taaggaaaaa ggcaacgaag ctagaaatgg cagcgtgcca aggattggta aattcttcat
    11821 actcaatccc atatttttcc tctaccagag ccttgagtgg atttttaaga aagatcttat
    11881 tggtcaagag ttgggcagaa gttttgaatt ctccattttg gatataagca gcatagaggg
    11941 attttttggc tagttcccta tcttggtcta gcaagagttt ttctcgcgaa acggcagctt
    12001 cctcggtatc ttttggagtt gaaacggata catattctcc accagccatt gaaaaggcac
    12061 cagctaagat agccgtaaaa cctgataaaa agataatcca gatattggtc gtggcactgg
    12121 caactccgat aaccacacca gcaatggaaa taattccatc gttagcatca agaacacccg
    12181 cacgcaggat atttaaacga cctgcaaaat ttgaatcaat ttcgtgattt gtttctgacg
    12241 ctaaatttca agttcaagtt agccatcaag aagtcttctc tgggtgactt gtagtccaag
    12301 cattttttag gatagttgtt aatccacttt tcgatgaatg cgacttcttt gggagtcatt
    12361 ttcttggttc ccttaggtaa ccatctacga atgagcctgt tgtgattctc attagttccc
    12421 ctttcccaag aggcataggg atgtgcataa taaatgtgct cctcagaaaa tacattagac
    12481 aagcgattga attccgttcc attatctgcc gtgatggaaa gaatcttgtg ttgttttaag
    12541 atgagtttta gagcctgatt gaccacatca gcacttttat ttggaatcaa tcggatgatc
    12601 tgatgtctac tttttcgatc cgtcaagaca agcaagcagt agtttttcgc tctcgtaagt
    12661 agaactgtat caatctcata atgcccattc tccaagcgaa aattgatagc ttcaagccgc
    12721 tgttcgatgg attgaccagc aggtttaaag ttggtgctgg cctgtttctt aagcgctttt
    12781 ccttttctag ggtaaagcag atcctgtttg cttaacccca attttccatg atgaatccaa
    12841 tagtaaatgg ttgaaattcc cacgttaacc cctttagcca tcaccatcat ttcaggcgaa
    12901 aatttttggt tatgatagtg gagaatcttt tcctttagtt ccttggtcaa gcttgatttc
    12961 ttgaccgagc gcttgcgatt gttttcataa gactgttgag catagtcggc agaataaacc
    13021 tctttgaagc gcccttttcc aagacattgt cggactgtcc cacgcttgat ttcagtgtgg
    13081 atagtttgag gaacttttcc aagcagagag gcaatttctc tatttgattt cccttctttt
    13141 ttccatcttt cgattaagcg acggctatcg attgtcaaat gttcgccttt tgtagtataa
    13201 tggttttgca tctctgtgcc tttcttgtgt ttgtggttga acaacaagta taacacagag
    13261 gtgttttctt atgcctacaa gagctatcgg ctagttgaac catctaattt ttaggagggc
    13321 tgggtggcta acttcattat agaactttca tttacgaaca tatagtaaaa tgaaacaaga
    13381 acagaacaaa tcgatcagga cagtaaaatc tatttctaac aatgttttag aagcagaggt
    13441 gtactattct agtttcaatc tattatattt ttgtttttta tcaaaaaata ctttacaagt
    13501 tcttaaaaac atgatatagt aataaagctt agaaaatgag atgatgtttt ctagcaaata
    13561 taaacccgag taaaaaatgc ctacggacag gcagggttga atgccgaagc gtggttgaaa
    13621 agccacatta ttgatagggt taaaagccta cttttataag ttgatgttag gacacttgtc
    13681 ctaattcata aatttttagt gtggtgaaag cacacgtcat cttgtgaaac gatcaataaa
    13741 gtacgtaata tttgctacta gagagttagg aaacatcggg aacagacata ctcaacagaa
    13801 accaaaataa acacgtcaga agattgcaga gcaggtgaaa acctgctctt ttttcatgag
    13861 tcaaccttta gttccttagt tttcataagg tcctaaaaat attgaaagga gtatgttttg
    13921 aaagagttag atcaaaacca agccccaatt tatgaggcct tggtgaagtt acgcaagaaa
    13981 aggattgttc cctttgatgt tccaggtcac aagcgtggac ggggaaatcc agaacttgtc
    14041 gaactcttag gagaaaaatg tgtaggcatt gatgtcaatt cgatgaaacc tttggataat
    14101 ttaggccatc ctatttcgat tattcgtgat gcagaggagc tggctgcaga tgcttttgga
    14161 gctagccatg cctttctaat gattggtgga acaacttcat cggtgcagac tatgattctg
    14221 gcaacctgca aggcaggaga taagattatt ctgccacgaa atgtccataa atctgctatc
    14281 aatgcgttgg ttctatgtgg tgccattccc atctatatcg agatgagtgt agatcctaag
    14341 attggtatcg ctttaggtct tgaaaatgac cgagtagcac aggccataaa ggaccatcca
    14401 gatgctaagg ctatcctaat caacaatcct acttactacg gcatctgttc agacctaaag
    14461 gggttgacag aaatggctca tgaagctggc atgatggttt tagtagatga agcccacgga
    14521 gcgcatttgc atttcactga taaacttcca atttctgcta tggatgcagg ggctgatatg
    14581 gcagcagttt ccatgcataa gtctggtggg agtttgaccc aaagctccat tttacttatc
    14641 ggggagcaga tgaattctga atacgttcgt cagataatta acctgaccca gtctacatct
    14701 gcctcttact tgttgatggc tagtttggat atttcacgtc gcaacttggc ccttcgtggt
    14761 aaagagtcgt ttgagaaagt cattgagcta tctgagtatg cccgccgtga aatcaatgct
    14821 atcggtggct actatgccta ctcaaaagag ttaatagacg gtgtttcggt ttgcgatttt
    14881 gacgtaacta agctgtcagt ttacactcag ggtattggct taacaggtat cgaggtttat
    14941 gacctcttgc gagacgaata cgacattcag atcgagtttg gtgatatcgg caatatcttg
    15001 gcctatattt ccatcggcga ccgcatccaa gacatcgagc gcttggttgg tgctctggct
    15061 gatattaaga gactctattc aagagatgga aaagatttga tagcaggaga atatattcag
    15121 cccgagttag tgctgtctcc gcaagaagcc ttctattcag aaagaaaaag tttaactttg
    15181 gatgattctg ttggacaggt ctgtggagaa tttgttatgt gttaccctcc aggtattcct
    15241 atcttggctc ctggtgaacg cattacacga gaaattgtcg actatatcca attcgccaag
    15301 gaacgtggtt gctccctcca agggacggaa gatccagagg tcaatcatat caacgttatt
    15361 aagagaaaga caaactataa gaaaagtcaa tagttttatc taaactattt cttatttcaa
    15421 tttgatgatt tggcgatgat tttagagcac ggcaaaaagc ccttgaatta gaagcggtca
    15481 atcgcttaat ttctatcagc ttatcaaatc ctgcctcaag ccttttctga ggattagggt
    15541 agcgtgtcaa gagttggtag gtatattctg aatgctttcc aacgatttta tccaactcag
    15601 gaaagatgat atcaagacaa cgagtgtatt gtactttcca atcagactgt tttttcttga
    15661 gacgatgaat atgtctagcc agtattttta gttctacttg ccgattatcg tgttgaaatt
    15721 gttcacgatt ggggtcagaa agaagtttaa gagcgatgcc atgagcgtct ttcttatccg
    15781 ttttagtttt gcgaagtgat aatgatttgg caaatttctt gatgagcaaa ggattgtagg
    15841 tgtaaacttt atatccttgt tcatgcagga agttcagtag attaaaggca taatgtccgg
    15901 tattttcaag agcgatgaga cagtcttggt tgagctgtcg aagagacaga tctaagagtt
    15961 caaaaccagc tttattattt gaaaaagtga gtggtttaag aacagttttt cctggaacat
    16021 tcaaggctgt aacatcgtgt ttatttttag cgacatcaat gcccacataa agcatgggag
    16081 tatctccaga tatagtattt caagtctact gggttatcca cgaacttttt gccttgttac
    16141 cttagacgag ataaaacgtc tatgcgttat caaactcatt accaattgaa acaaaaaact
    16201 gtggttagag cctttcggaa atcgtcaagc gattggagga aatgaactaa tccacagtgg
    16261 cttattccaa gtataccact tgggctttgg cagtagctaa ctgcgctaaa tataatataa
    16321 ggagaaatag atggatttat ggttttctga agttcatact ccagatgtca aattgtctct
    16381 gagaacagcc aagcaacttt acgctggaaa aagtgaatgg caggatatcg aagtcttgga
    16441 tacgccagct tttgggaaaa tactgatttt aaatggccat gtcttgttct cagatgcgga
    16501 tgatttcgtc tacaatgaaa tgaccgttca cgttcccatg gctgtccacc caaatccaaa
    16561 gaaagtattg gttattgggg gtggtgacgg cggtgttgcc caagtattaa ccctctatcc
    16621 tgaactggag caaattgata ttgtggaacc ggatgagatg ttggtcgagg tctgtcgtga
    16681 gtatttccca gactttgctg cagggctaga tgatcctcgt gttaccattt actaccaaaa
    16741 tgggctacgc tttttgcgaa actgcgaaga tgattacgat attatcatca acgatgcgac
    16801 agatccattt ggccatacgg aaggactctt taccaaggaa ttctacggca atagttatcg
    16861 agctctgaag gaagacggca tcatgattta ccagcatggg agtcccttct ttgacgagga
    16921 tgagtcggcc tgccgaagca tgcaccgcaa ggtcaatcaa gcctttccaa tcagtcgggt
    16981 ttatcaggcc catattccaa ctagcccagc tggctattgg ttgtttggat ttgcatcgaa
    17041 aaaataccac cctgtcaaag attttgacaa ggaaggctgg aaaaaacgcc agcttttcac
    17101 agaatactac actgcaaact tacacgtggg agcctttatg ttgcccaagt atgttgagga
    17161 cattttagaa gaagaggaag gaaaaaaatg agtcgtttac tagttattgg ttgtgggggc
    17221 gttgcccaag ttgctatttc aaagatttgt caagatagcg aaacatttac agagattatg
    17281 attgctagcc gtaccaagtc aaaatgcgat gacttgaaag cgaagctaga aggcaaaaca
    17341 agtactaaaa ttgaaactgc agcacttgat gctgacaagg ttgaagaagt gattgccctg
    17401 attgaaagct acaaaccaga agctgttttg aatgtagctc tgccttatca agatttaacc
    17461 attatggatg cttgtttggc aacaggtgtt cactatatcg atacagccaa ctacgaagca
    17521 gaagacacag aagaccctga gtggcgtgct atctacgaaa aacgttgtaa ggaacttggt
    17581 tttacagcct actttgacta ctcatggcag tgggcttatc aagagaaatt caaagaagca
    17641 ggcttgactg ctcttcttgg ttctggtttt gacccaggtg taactagtgt cttttcagct
    17701 tatgccctca aacactattt tgatgaaatc cattatatcg acattttaga ctgtaatggc
    17761 ggtgaccacg gttatccatt tgcaaccaac tttaatccag aaattaatct ccgtgaggtt
    17821 tctgcgccag gttcttactg ggaagatggg aaatgggtcg aagtcgaagc tatgtctatc
    17881 aagcgtgagt atgatttccc tcaagttgga caaaaagata tgtatctcct tcaccatgaa
    17941 gaaatcgaat cattggccaa gaacattcca ggtgtcaaac gcattcgttt ctttatgact
    18001 tttggtcaat cttacttgac gcacatgaaa tgtcttgaaa atgttggact ccttcgtacg
    18061 gataccatta actttaacgg ccaagaaatt gttccaattc aatttttgaa agccttgctt
    18121 ccagatcctg ccagtcttgg gccacgtaca gtcggaaaaa ccaatattgg atgtatcttt
    18181 acaggtgtca aagacggtgt caaaaagact atctatatct acaatgtctg cgaccatcag
    18241 gaatgttacg cagaggttgg ttcgcaagct atttcttata cgacaggagt tccagccatg
    18301 attgggacaa aattagtcat gaacggaact tggaaacaag ctggagtgta taaccttgag
    18361 gagttagatc cagatccatt catggaagct ttgaatgagt atggtttgcc atgggttgtg
    18421 gttgaaaatc cacaaatggt ggactaatga agttagaaca agtaccaaca ccagcctatg
    18481 ttattgactt ggccaagtta gaagctaatt gccgcattct acaatatgta caagaagagg
    18541 ccggttgcaa ggtcttgctt gcccagaagg catattccct ctacaaaact tatcccttga
    18601 ttagccagta tctatcaggt acgacagcta gtggactcta tgaggccaaa ttggcaaggg
    18661 aagaatttcc tggtgaagtc catgtatttg cgcctgcttt caaggatgca gacttggagg
    18721 aattgctaga gataatggac catatagtct ttaactcaga gagacagttg cgtaaacacg
    18781 gtccgcgttg tcgagaggct ggtgtcagtg ttggtttgcg cctcaaccct cagtgttcaa
    18841 ctcaaggaga tcacgcgctc tatgaccctt gtgcaccagg ttctcgcttt ggagttacta
    18901 tagacaagat tccgagtgat ttgctagatt tggttgacgg acttcatttt catacccttt
    18961 gcgagcaggg agcagatgat ttacaaacaa ctttgaaagc agtagaagaa cagtttggtc
    19021 cctacttaca tgaggtaaaa tggctcaata tgggtggtgg tcatcatatt acaagagaag
    19081 gttacgatgt ggatttgctg atttcagaaa tcaagcgtat ccgaaaaact tacaatcttg
    19141 aaatctatat cgagcctggt gaagccattg cgcttaatgc gggttattta gcaactgagg
    19201 tattagatat tgtagaaaac ggtatggaaa tcttggtttt agacgcctct gcgacctgcc
    19261 atatgcctga tgtacttgag atgccctatc gtccaccttt gagaaatggc tttgagtcac
    19321 aggaaaaagc ccatacctac agactttctt ctaatacctg tctgacgggc gatgtgattg
    19381 gtgattatag ttttgaaaat ccagtccaaa tcggagacag actttatttt caagacatgg
    19441 ccatttattc ttttgtcaaa aataatacct ttaatggtat tggattgcca agtctctatc
    19501 tcatggacga acagggagac tgtagcttac tcaaagcttt tggctatcaa gactttaaag
    19561 ggagattatc atgatggaca gtccaaaaaa attaggctat cacatgccag cagagtacga
    19621 accccatcat ggtaccctca tgatatggcc gactcgacca ggatcatggc cttttcaagg
    19681 aaaggctgct aaaagagcat ttactcagat tatcgagacc atagcagaag gggaaagagt
    19741 ctatcttttg gtggagcagg cctatctatc tgaagcccaa tcctatcttg gagacaaggt
    19801 tgtttattta gacattccca ccaatgatgc ctgggcgcgt gatactggcc caaccattct
    19861 cgtcaatgat aaaggtaaga aattagccgt ggattgggcc ttcaatgctt ggggaggcac
    19921 ctatgatggt ctttatcaag attatgaaga ggatgaccaa gtagccagtc gttttgctga
    19981 ggccttggaa aggcctgtct atgatgctaa accttttgta ctggaaggag gcgcaatcca
    20041 tagcgatggt caaggaacta ttctcgtaac tgaaagttgc ttgcttagtc ctggtcgcaa
    20101 tcctaacttg actaaagagg agattgaaaa cacattatta gaaagtcttg gtgctgaaaa
    20161 agttatttgg cttccttatg gtatttatca ggatgaaacc aatgaacacg tcgataatgt
    20221 tgctgccttt gttggtcctg ctgagcttgt tttggcttgg acagatgacg aaaatgatcc
    20281 ccagtatgcc atgtcaaaag cagatctcga actcttagaa caggaaacag atgcaaaagg
    20341 ttgtcacttc accattcata aattgcctat ccctgcagtt cgacaagttg tgacagaaga
    20401 agatttgcca ggctacatct atgaagaagg agaagaaaag cgatacgcag gtgaacgact
    20461 agcagcttcc tacgtaaact tttatatcgc caacaaggct gtcttggttc cacagtttga
    20521 ggatgtaaac gaccaagtgg ccttagatat cctcagcaag tgtttcccag accgtaaagt
    20581 tgtcggaata ccagccagag atattctctt aggtggtggc aatatccact gtatcaccca
    20641 acaaattcca gaataggaga aaaagatgag aaatgtaaga gttgcaacca ttcagatgca
    20701 atgcgctaag gatgtggcaa caaatatcca aaccgcagag cgtttagtac gtcaggctgc
    20761 tgagcaagga gcccaaatta ttctcttgcc cgagttgttt gaacatccct atttctgtca
    20821 ggaacgtcag tatgactact accagtatgc ccaatctgta gcggaaaata ctgccattca
    20881 gcattttaag gtgattgcta aggaactaca agttgtttta ccaatcagtt tctatgaaaa
    20941 agatggtaat gtcttgtata actctattgc cgtcattgat gcagatgggg aagtgctggg
    21001 cgtttatcga aagacccata taccagatga ccattattat caagaaaaat tctatttcac
    21061 gcctggtaac actggtttca aggtctggaa tactcgctat gctaagattg gtatcggtat
    21121 ctgttgggat caatggttcc ctgaaacagc gcgctgtctt gcattgaatg gtgctgaatt
    21181 gctcttttat cctacagcta tcggttcaga gccaattttg gatacagata gttgtggtca
    21241 ctggcaacgt actatgcaag ggcacgcagc agcgaatatt gttccagtca tcgcagccaa
    21301 tcgttatggt ttagaggagg ttactcctag tgaggaaaat ggcggacaga gctccagtct
    21361 tgacttctac ggttcctcct ttatgacgga tgaaacagga gctattctag aacgagctga
    21421 aagacaagaa gaagctgttc tgttagctac ttatgaccta gacaagggag caagtgaacg
    21481 cctaaactgg ggcttgtttc gagatagaag accagaaatg tatagacaaa ttacagatta
    21541 gtgtgggaga aatgagagat tcattctgct agactaactt cttattagta actataagat
    21601 actatggcat ctagtaaatc gatttttatg attcgctatt cttgtctatt gattagtccg
    21661 tattttaaaa tattagcaaa aaagcaaata gcagtaactt ctgtctattt gcttttcttt
    21721 tttatagaat atatttctca atagcacgcg caacgccgtc ttcttcgttg cttgaggtaa
    21781 cggcatccgc aagagatttg atataatcgc tggcatttcc cattgcaatc ccaagccctg
    21841 caaactggag catttcgata tcgttattag catcgcccat ggccataatc tctgaggaat
    21901 caatcttcaa aatctcagct agtcgtgaaa gagcagtagc ctttgtcgtt ccaagcggca
    21961 ttgcttcata aatgacaggc tgcgaacgaa ctccactgaa tcgttggcaa agctcttcag
    22021 caaaacgctg ctcaaaatcg tctgtttgtt cttttgttcc taaaaacata ccttggaaca
    22081 tccggaactt tccactagtc gcttcttcaa gagaaatttc agtcaggtct gaaaatacta
    22141 gtttagcatc attttcaata acttgattgg gcttgtcacc gagaacaaaa taatgtgact
    22201 cgtcaaaaag tgtcaactga acatcactct tttcagcaag gtcatagagg tattcgatgt
    22261 cagctggact cagttctttc cagtcaacta gactccaatc actggtctgg tgagttgaac
    22321 aaccgttgtt aacaataata tattcgttct ggaggtcaag ctccagtttt ttgtagtagg
    22381 ggaggacacc gaaaaggggg cgacccgtac agagaaccag tttgacacct ttttcaatgg
    22441 ctttgtgaat agcagtaatg tgagcttgtg ggatttcctt ggcttcattg aggagggtgc
    22501 cgtccatatc caaggctagt agtttaatca taggtcttcc ttctttatct tttgctatta
    22561 ttatagcata ttttggagaa gaaattgata gaaagcttga gactaattga ttttatagtt
    22621 taagatgttt tgatgacaat tcatgatttg aagaggatat ttcgcaaaga tatgctatac
    22681 tatgtttgtc aatgttgcaa ctagacaaat taaaaaacca acttaatata atagtttttt
    22741 tgtaagtagg tatgagtagc agattactca actaatctga agaataatgg aggaaatata
    22801 tcatgatttt aatgacaaaa aatataaatc taacaaatga agaattagag ctgatacaag
    22861 gtggagcaga tccatatggt aaaaatccta atggtaggta cgattgggaa atagaaccag
    22921 tattaactct gctggttcat ggattttgtc ccagaggcac ctatgattca ggatatattg
    22981 gaggaggtaa tcatctttgc aaaggaagtg ctgcgagatt ttaagtaaaa tttattagga
    23041 atatgaagaa acaaggggag aaaacagagg atttaatatg aaaaaacgag ctattcaaat
    23101 tttactagca ttgtccttaa ttttttacaa atcaacttgg ttttggaggc ttttcaatta
    23161 tctcgcaaag ccctatctac cagcaagtcg tgaatttttt cagattctgc ttttgatgga
    23221 gagcggagtt cttttcttag cggtcatcta tctactggtt tttgcaggaa agaaaatttt
    23281 tcatttcaag tggcagctga ggtacttcat ctacctttta ctgggctaca tcatttcata
    23341 tatgtctgac ttcctctttt cgtatttcat atccctgtct tcaaatcaga tttctttgaa
    23401 tgaaacggta gaaatgatgg ggagacagga gttcccttat ttcttgctca tcgtttgctt
    23461 catcgcccct attgctgagg aattgattta tcgaggtgtg cttatgacaa cctttttcaa
    23521 aaactcacct tggtacggag atgttttgct ttctgctatt attttcggtt atattcatat
    23581 caattttgct ttaactcctc ttgctttttt catttatgct agtggaggtc ttattttagc
    23641 tctattgtat cgcatgacta aaaatctcta ctatccaata ctagttcata ttctcattaa
    23701 tatcactgcc ttctgggatg tgtggttgct cctattttca ggaagttagc ttactaaaat
    23761 aatgtcggaa ctttccggca ttttcttttt tcacaaatag tcaacgtttt tcttttcgat
    23821 attgtagtgg tgtgtatcca gttatttttt tgaattgatt ttgaaaataa ggttgacttg
    23881 agaaaggcag atagtgaaga tagttaagaa gaataggatg ttcttttttc ctttttggaa
    23941 aacttctaaa atatggtata atgaaaagat aaagaagttg ggggtagaag atgaacattc
    24001 aacaattacg ctatgttgtg gctattgcca atagtggtac ttttcgtgaa gctgctgaaa
    24061 agatgtatgt tagtcagccg agtctgtcta tttctgttcg tgatttggaa aaagagttgg
    24121 gctttaagat tttccgtcgg accagctcag ggactttctt gacccgtcgt gggatggaat
    24181 tttatgaaaa atcgcaagaa ttggttaaag gatttgatat ttttcaaaat cagtatgcca
    24241 atcctgaaga agaaaaagat gaattttctg ttgctagcca gcactatgac ttcttgccac
    24301 caactattac ggccttttca gagcgctatc ctgactataa gaacttccgt atttttgaat
    24361 caactactgt tcaaatatta gatgaagtgg cgcaagggca tagtgagatt gggattatct
    24421 acctcaacaa tcaaaataaa aaggggatta tgcaacgggt tgaaaaatta ggtctggagg
    24481 tcatcgaatt gattcctttc catacccata tttatctccg tgagggtcat cctttagccc
    24541 agaaagagga attagtcatg gaggatttag cggatttacc aacggttcgt t
//
LOCUS       DAVFER010000029        23967 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1105170250
            SAMEA2167659-rid19724873.denovo.029, whole genome shotgun sequence.
ACCESSION   DAVFER010000029 DAVFER010000000
VERSION     DAVFER010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2167659
            Sequence Read Archive: ERR388902
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 23967)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23967)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928716.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928716.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 04:07:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,118
            CDSs (total)                      :: 2,073
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 120
            CDSs (without protein)            :: 120
            Pseudo Genes (ambiguous residues) :: 0 of 120
            Pseudo Genes (frameshifted)       :: 67 of 120
            Pseudo Genes (incomplete)         :: 47 of 120
            Pseudo Genes (internal stop)      :: 34 of 120
            Pseudo Genes (multiple problems)  :: 23 of 120
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23967
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2167659-rid19724873.denovo.029"
                     /strain="1105170250"
                     /db_xref="taxon:1313"
     gene            complement(48..197)
                     /locus_tag="VU534_001304"
     CDS             complement(48..197)
                     /locus_tag="VU534_001304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1513888.1"
                     /translation="MDKMKPVFQALNKELIQENLTLTIICVGGYVLEYHGLRATQDVD
                     AFMAL"
     gene            complement(190..474)
                     /locus_tag="VU534_001305"
     CDS             complement(190..474)
                     /locus_tag="VU534_001305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002923859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1513889.1"
                     /translation="MDWYDYMIQASKQSQFNASHWFRYLRKVIFEDYSYLTNQDVEKL
                     LDSKELTRFQKISLKYAFQEHTPTHKYVISLNKPAKLTNVQKLMEKYKHG"
     gene            complement(1908..3131)
                     /locus_tag="VU534_001306"
     CDS             complement(1908..3131)
                     /locus_tag="VU534_001306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HEU1513890.1"
                     /translation="MITKQSAFLQNRATILEFLYRNPATSRTDIVNETGLTPATTTNI
                     IKELSEQSLIYETGDEFSEFSGSGRRRKTISITDNIPYVVGGIEINVLGIFLSLCDLQ
                     GKTLFETEILNEDYPISEINSTITNMIKTAIEYVPLETKLLGFGLSIPGHYNKDSGSI
                     ITNNPIWESFNLLNVIKRFNFPFIVKNNIDCMAIGQYLFNPHNTPDNFIFLHAGLGIY
                     TSFFTKEKIGASKNPYIGEIGHTIVELNGQYCECGKKGCLQTYISDAWLIKHAQLLFK
                     NSQLTVLKSLVKTEKDIHLDTLLTAYNLGDSALRQQIDKGVNLLATSIANLLLINPAD
                     KIYINSQLLNYQPFTHEVRDKIQDQLHFVPFTRNIEIEILPYNKHRGSIGACALAIVA
                     FFIEHSNVLQDIISP"
     gene            3299..4621
                     /locus_tag="VU534_001307"
     CDS             3299..4621
                     /locus_tag="VU534_001307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001059752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEU1513891.1"
                     /translation="MNNILAFLETKVAPFGEKVGNQRHLKAIREGFMMAMPLILVGSL
                     FLILISWPQEAFTNWLNSVGLLSILTTMNQSTVAIISLVACFGIAYRLSEGYGTDGPS
                     AGIIALSSFVLMAPRFSSMVYDKNGEQVKQLFGGAIPFSSLNASSLFMAITIGLVTAE
                     IYRMFIQRGITIKMPSGVPDVVSKSFSALLSGFTTFVLWALVLKGLEAAGVAGGLNGL
                     LGAIVGTPLKLIAGTLPGMILCVIVNSFFWFCGVNGGQVLNAFVDPVWLQFTTENQEA
                     VAAGQTLQHIITLPFKDLFVFIGGGGATIGLAICLFLFSKSRANKTLGKLAIIPSIFN
                     INTAILFTFPTVLNPIMLIPFIATPTINALITYVSMAVGLVPYTTGVILPWTMPPIIG
                     GFLATGASWRGALLQVVLILVSVAIYYPFFKIADKRNLEKEKATVGGK"
     gene            4623..6509
                     /locus_tag="VU534_001308"
     CDS             4623..6509
                     /locus_tag="VU534_001308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000236922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4838 domain-containing protein"
                     /protein_id="HEU1513892.1"
                     /translation="MVIRVFDQQKNTYSSFALEELSYYMNRVFKTNIELVEEKEADIF
                     VGLVNKEDRKDHVLISLDKGKGRIESNTIVGLLIGIYRMFHEFGVVYTRPGRRHDFVP
                     ELRFEDFLDKQLSIDETASYYHRGVCIEGADSFENILDFIDWLPKIGMNSFFIQFENP
                     YSFLKRWYEHEFNPYLNKEQFSNELVQELSDRLDKELQKRGLIHHRVGHGWTGEVLGY
                     SSKFGWESGLSISEEKKPYVAEINGKRELFNTAPILTSLDFSNPDVADKMVEIIKDYA
                     KKRPDVNYLHVWLSDARNNICECENCRQELVSDQYIRILNQLDRALTSEGLDTKICFL
                     LYHELLWAPQKEKLDNPERFTMMFAPITRTFEMSYADVDFDNSIPTPKPYMRNKIILP
                     NSLEENLSYLFEWQKAFKGDSFVYDYPLGRAHYGDLGYMKISQTIYRDVSYLSNLHLN
                     GYISCQELRAGFPHNFPNYVMGEMLWKKTRSYEELIEEYFSALYGENWQSVVEYLEKL
                     SIYSSCDYFNAIGSRQSDVLANHYYIAYNLADNFLPIIEENISKLLNSQKDEWKQLSY
                     HREYVVKMAKALYLQATGKTRQAQDEWRNVLNYIRGHELLFQSNLDVYRVIEVAKNYA
                     GFHL"
     gene            6677..7021
                     /locus_tag="VU534_001309"
     CDS             6677..7021
                     /locus_tag="VU534_001309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000836781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEU1513893.1"
                     /translation="MKSKEEINMLGFTIVAYAGDARSDLMDALAFARDGYFEQARELV
                     ESANDSIVSAHREQTNLLAEEAYGDNFEVSFIMIHGQDTLMTTMLLYDQVKFFIDEYE
                     RIRKIEEHIGLQ"
     gene            7031..8443
                     /gene="lacG"
                     /locus_tag="VU534_001310"
     CDS             7031..8443
                     /gene="lacG"
                     /locus_tag="VU534_001310"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HEU1513894.1"
                     /translation="MENLQVKALPKEFLLGTATAAYQVEGATRVDGKGINMWDVYLQE
                     NSPFLPDPASDFYYRYEEDIALAAEHGLQALRLSISWVRIFPDIDGDANVLAVHYYHR
                     VFQSCLKHNVIPFVSLHHFDSPQKMLETGDWLNRENIDRFIRYARFCFQEFTEVKHWF
                     TINELMSLAAGQYIGGQFPPNHHFQLSEAIQANHNMLLAHALAVLEFHQLGIEGKVGC
                     IHALKPGYPIDGQKENILAAKRYDVYNNKFLLDGTFLGYYSEDTLFHLNQILEANNSS
                     FIIEDGDLEIMKRAAPLNTMFGMNYYRSEFIREYKGENRQEFNSTGIKGQSSFKLNAL
                     GEFVKKPGIPTTDWDWNIYPQGLFDMLLRIKEEYPQHPVIYLTENGTALKEVKPEGEN
                     DIIDDSKRIRYIEQHLHKVLEARDRGVNIQGYFIWSLQDQFSWANGYNKRYGLFFVDY
                     ETQKRYIKKSALWVKGLKRN"
     gene            8512..10191
                     /locus_tag="VU534_001311"
     CDS             8512..10191
                     /locus_tag="VU534_001311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEU1513895.1"
                     /translation="MDKLVAAIEKQQGKFEKISTNNYMMAIKDGFIATMPLIMFSSFL
                     MIIIMIPKNFGVELPSPAIVWMRKVYMLTMGVLGIIVSGTVGKSLVGNVNRKMPHGKV
                     INDISAMLAAICSYLVLTVTLVVDEKTGSTSLSTNYLGSQGLITSFVSAFITVNVYRF
                     CIKRDITIHLPKEVPGAISQAFRDIFPFSFVLLISGLLDIVSRFSLDVPFAQVFQQLL
                     TPIFKGAESYPAMMLIWFMCALLWFVGIHGPSIVLPAVTALQLSNMEENAQLLANGQF
                     PYHSLTPNFGNYIAAIGGTGATFVVPFILIFFMRSKQLKSVGKATITPVLFAVNEPLL
                     FGMPVILNPYLFVPFLMTPPVNVFLGKVFIDFFGMNGFYIQLPWTFPGPLGLLIGTNF
                     QLISFVFLSLILVVDILIYLPFCRAYDRQLLVKEDIASSNDIILEEDTSEIIPGEIDE
                     IKSKELKVLVLCAGSGTSAQLANAINEGANLTEVRVIANSGAYGAHYDIMGVYDLIIL
                     APQVRSYYREMKVDAERLGIQIVATRGMEYIHLTKSPSKALQFVLEHYQAV"
     gene            complement(10317..11756)
                     /locus_tag="VU534_001312"
     CDS             complement(10317..11756)
                     /locus_tag="VU534_001312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HEU1513896.1"
                     /translation="MNKSMIRYLLSKLLLIEAVLLLVPVAIAVYYRESSQVFTALFST
                     IGILVLLGGSGSLQKPKNQRIYAKEGVLIVALCWILWSFFGGLPFVFSGQIPSLIDAF
                     FEISSGFTTTGASILNDVSVLSRSLLFWRSFTHLIGGMGVLVFALAIMDNAKNSHLEV
                     MKAEVPGPVFGKVVSKLKNTAQILYLLYLALFSLFVIIYYLAGMPLYDSFVIAMGTAG
                     TGGFTVYNDGIAHYGSSLITYLVSIGVLVFGVNFNLYYYLMLRRIKAFFGDEELRAYL
                     VIVLVSTGLISLNTLYLYPGFSKSFEMTFFQVSNIITTTGFGYGDITNWPLFSQFILL
                     FLMAIGGSAGSTAGGLKIIRGLILSKIAKNQILSILSPHRVLTLHVNKTVIDKDTQHK
                     ILKYFVIYAMILLALIFIVSLDSNDFLVVTSAVFSCFNNIGPILGTTSSFSIFSPISK
                     ILLSFAMIAGRLEIYPILLLFMKRTWSKR"
     gene            complement(11760..13109)
                     /gene="trkA"
                     /locus_tag="VU534_001313"
     CDS             complement(11760..13109)
                     /gene="trkA"
                     /locus_tag="VU534_001313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Trk system potassium transporter TrkA"
                     /protein_id="HEU1513897.1"
                     /translation="MKIILVGGGKVGFALCRSLVAEKHDVLLIEQDEAVLNHIVSRFD
                     IIGILGNGADFAILEQASVQDCDIFIALTEHDEVNMIAAVLAKKMGAKETIVRVRNPE
                     YSNSYFKEKNILGFSLIVNPELLAARAIANIIDFPNALSVERFAGGRVSLMEFVVKST
                     SGLCQMPISDFRKKFGNVIVCAIERDHQIIIPSGDMTVQDKDRIFVTGNRVDMILFHN
                     YFKSRAVKSLLIVGAGRIAYYLLGILKDSRIDTKVIEINPEIASFFSEKFPNLYIVQG
                     DGTAKDILLEESAQHYDAVATLTGVDEENLITSMFLDRVGVQKNITKVNRTSLLEIIN
                     APDFSSIITPKSIAVDTIMHFIRGRVNAQYSDLQAMHHLANGQIETLQFHIKEANKMT
                     AKPLSQLKLKKGVLIAAIIRKGKTIFPTGEDMLEVGDKLLVTTLLPNITKIYDLIAR"
     gene            13297..14145
                     /locus_tag="VU534_001314"
     CDS             13297..14145
                     /locus_tag="VU534_001314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-adenosyl-l-methionine hydroxide
                     adenosyltransferase family protein"
                     /protein_id="HEU1513898.1"
                     /translation="MNNNLLVLQSDFGLVDGAVSAMIGVALEESPTLKIHHLTHDITP
                     YNIFEGSYRLFQTVDYWPEGTTFVSVVDPGVGSKRKSVVAKTAKNQYIVTPDNGTLSF
                     IKKHVGIVAIREISEVANRRQNTEHSYTFHGRDVYAYTGAKLASGHITFEEVGPELSV
                     EQIVELPVVATIIEDHLVKGAIDILDVRFGSLWTSITREEFYKLEPEFGDRFEVTIYH
                     ADMLVYQNQVVYGKSFADVRIGQPILYINSLYRLGLAINQGSFAKAYNVGVGSSWTIE
                     IKKIEG"
     gene            14160..14708
                     /locus_tag="VU534_001315"
     CDS             14160..14708
                     /locus_tag="VU534_001315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000403170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF-type riboflavin transporter
                     substrate-binding protein"
                     /protein_id="HEU1513899.1"
                     /translation="MEIKFTIKQVVAVGIGAALFVVIGMINIPTPVPNTSIQLQYAVQ
                     ALLSIIFGPIIGLLVGLIGHAIKDSLVGYGLWWTWIIASGLFGLVVGLFRKYVRVING
                     VFDWKDILIFNLIQLLANALVWGVLAPLGDVVIYQEAAEKVFAQGIVAGIANGVSVAI
                     AGTLLLLAYAGTQTRAGSLKKD"
     gene            14715..14972
                     /locus_tag="VU534_001316"
     CDS             14715..14972
                     /locus_tag="VU534_001316"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1513900.1"
                     /translation="MKIKEQTRKLAAGCSKQCFEIVDRTDEVSSKHGFEVVDETDEVS
                     NHTYGKAKLTWFEEIFEEYKMMGKAGQLVFFDVYRLVRQVS"
     gene            15074..16756
                     /locus_tag="VU534_001317"
     CDS             15074..16756
                     /locus_tag="VU534_001317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000656554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU1513901.1"
                     /translation="MKEAIIEWKDFSFRYETQQEPTLQGIDLTIYKGEKVLIVGPSGS
                     GKSTLGQCLNGIIPNIYKGQTYGEFLIKGQVAFDMSIYDKSHLVSTVLQDTDGQFIGL
                     SVAEDLAFALENDVTALDEMKGRVYKWAEKLDLLPLLDQRPQDLSGGQKQRVSLAGVL
                     IDESPILLFDEPLANLDPKSGQDIIELIDQIHKEEGTTTLIIEHRLEDVLHRPVDRIV
                     LINDGRILFNGSPDQLLATDLLTQNGIREPLYLTTLRQLGVDLVKEEQLANLDNLSIS
                     KGQVQLQNELAKETPALQSLFRLEEVSFSYDDRPILKSLHLDIKKGEKIAIVGKNGAG
                     KSTLAKAISSFIQTEGRYLWEKQDIKGDSVAERAERVGYVLQNPNQMISTNMIFDEVA
                     LGLRLRGVDEKEIETRVYETLKICGLYEFRNWPISALSFGQKKRVTIASILVLGAEII
                     LLDEPTAGQDQKNYTEIMEFLEELHQKGHTIVMITHDMQLMLDYSDRVLVMVDGELIA
                     DTVPASLLSDPELLVKANLKETSIFNLAKKLDVDPLDLTAFYKERREGCKLN"
     gene            16741..17571
                     /locus_tag="VU534_001318"
     CDS             16741..17571
                     /locus_tag="VU534_001318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEU1513902.1"
                     /translation="MQAKLIGYQHRDTVIHRLSGAGKLLFFILVSLAAMISYDTRMLL
                     LIAIFSVFLLYLSEIRFKDVSFVAVFATIFAVLNVLMVYLFSPEYGVGLYGERSVIWQ
                     GIGVYTLTSQELFYLLNLAIKYLCTIPLAIIFLMTTHPSQFASSLNQIGVPYKIAYSV
                     SLTLRYIPDLQEEFFTIKMSQEARGMELSKKASLMQRIKGNLLIITPLIFSSLERIDT
                     IATAMELRRFGKEKKRTWYSYQALKKGDYITLLLATLFLVVSLLLILQNQGRFYNPWK
                     "
     gene            17764..18267
                     /locus_tag="VU534_001319"
     CDS             17764..18267
                     /locus_tag="VU534_001319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000181367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (cytidine(34)-2'-O)-methyltransferase"
                     /protein_id="HEU1513903.1"
                     /translation="MTNHIVLFEPQIPQNTGNIARTCAATNSPLHIIKPMGFPIDDRK
                     MKRAGLDYWDKLEIYFYESLEDFISQMKGKLYLISKFAEKVYSEVDLSTDEDHYFLFG
                     REDKGLPEDFMREHPEKALRIPMNDEHVRSLNVSNTVCMIVYEALRQQNFAGLELVHT
                     YEVDKLK"
     regulatory      18321..18555
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            18720..19283
                     /locus_tag="VU534_001320"
     CDS             18720..19283
                     /locus_tag="VU534_001320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEU1513904.1"
                     /translation="MTNTRRLSTIAILSAISFVLMYFDFPLLPAASFLKIEFSILPVL
                     VGLVVMDLPAALGVLLLRSLLKLLLNSQGVNTYIGLPMNIVALGVFVIVFALIWKKER
                     TTLRFLLGSLAGTIGLTLAMLVLNYVYAVPLYAKFANFDIGKILGLSNYLMTMVLPFN
                     LIEGVIFSVSFWLLYVLLKPTLKHYER"
     gene            19297..19923
                     /locus_tag="VU534_001321"
     CDS             19297..19923
                     /locus_tag="VU534_001321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001853067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HEU1513905.1"
                     /translation="MKGSFALLLFVILGYMVKFYPEMLVNFDQSIQTAIRGDLPDYLT
                     ILFRALTRLIDIPVIITWVVITAFVFYRKRWKIESFFMLGNLALAGLLIVTFKNIYQR
                     PRPAILHLVEEKGFSFPSGHSLAVTLMVGTLIVILSQRIKDQVWRKIVQIVLGLYLVS
                     VLVSRVYLGVHYPSDVLASLCVGLGVLFIEFPFYDKLRFQWRFKGKQK"
     gene            19951..20340
                     /locus_tag="VU534_001322"
     CDS             19951..20340
                     /locus_tag="VU534_001322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000867286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome partitioning protein ParB"
                     /protein_id="HEU1513906.1"
                     /translation="MKVNIADLHLTQLYLSEKKLQDIQMLYQSAETIQVDPISILAFG
                     DCLLITDGHHRAYQALLAGRDTISAEWDRDGGDELYHLYAQACEERKIYSVFDLEDRI
                     LAQDGYEAKWYNWCDGFNQAATLLLKR"
     gene            20345..20794
                     /locus_tag="VU534_001323"
     CDS             20345..20794
                     /locus_tag="VU534_001323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000333655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HEU1513907.1"
                     /translation="MCFVPYYKVNHCEEAFAWYQDVNLVYLVDGVKLPYSQATLEAMY
                     SYLDRHGELFWIEVKEKGEWFPIGDITLSQDNLPIVIGNSAYQHRGLGKKILSALIEL
                     ARVKGWKELRVKKIYTYNHASRRCFKSLGFVENGATEKGMSFILELV"
     gene            20922..21509
                     /locus_tag="VU534_001324"
     CDS             20922..21509
                     /locus_tag="VU534_001324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="HEU1513908.1"
                     /translation="MELEVFAGQEKSELSMIEVARAILELRGRDHEMHFSDLVNEIQN
                     YLGTSNSDIREALPLFYTELNFDGSFISLGDNKWGLRSWYGVDEIDEEIIALEENDDD
                     EVAPKAKKKRVNAFMDGDSDAIDYNADDPEDEDAYEADPALSYDDENPDDEKNEVEAY
                     DAEINEIAPDDLGEDVDLNEDDDEFSDDDAETSEE"
     gene            21899..23506
                     /locus_tag="VU534_001325"
     CDS             21899..23506
                     /locus_tag="VU534_001325"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HEU1513909.1"
                     /translation="MSTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPY
                     INIDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRK
                     ERRGEYLGATVQVIPHITDALKEKIKRAALTTDSDVIITEVGGTVGDIESLPFLEALR
                     QMKADVGADNVMYIHTTLLPYLKAAGEMKTKPTQHSVKELRGLGIQPNMLVIRTEEPA
                     GQGIKNKLAQFCDVAPEAVIESLDVEHLYQIPLNLQAQGMDQIVCDHLKLDAPAADMT
                     EWSAMVDKVMNLKKQVKISLVGKYVELQDAYISVVEALKHSGYVNDAEVKINWVNAND
                     VTAENVAELLSDADGIIVPGGFGQRGTEGKIQAIRYARENDVPMLGVCLGMQLTCIEF
                     ARHVLGLEGANSAELAPETKYPIIDIMRDQIDIEDMGGTLRLGLYPSKLKRGSKAAAA
                     YHNQEVVQRRHRHRYEFNNAFREQFEAAGFVFSGVSPDNRLVEIVEIPENKFFVACQY
                     HPELSSRPNRPEELYTAFVTAAVENSN"
BASE COUNT         7182 a         3991 c         5182 g         7612 t
ORIGIN      
        1 aaaaataggc tccataatat ccatagggga tttacccact acaaatatta tagagccata
       61 aaagcatcaa catcttgtgt ggcacgtaaa ccatgatatt ctaagacata accaccgaca
      121 cagataattg ttaaagtcag attttcctga attaattcct tatttagggc ttggaagacc
      181 ggtttcattt tatccatgtt tgtatttctc catcaatttt tgaacattgg ttaacttagc
      241 aggtttattt aatgaaatca catatttatg agttggagta tgctcttgaa aggcatactt
      301 caagctaatt ttttgaaaac gggttagttc tttggagtct agcaactttt ctacatcttg
      361 gtttgttaaa taagaatagt cttcaaaaat aacttttcgc aaatagcgaa accaatggct
      421 tgcgttgaat tgtgattgtt tggatgcctg tatcatataa tcgtaccaat ccattgtctt
      481 cctcctataa aatttagttt atattattgt agtttatatt caaaaatgta gtttttctta
      541 attagctcgt atctatagga tgatactgaa aatcttcttg ttgctttaaa tcacaatcga
      601 aaaattctgt ttttcatctt agaaaagaat gtttagaaat gtaaaatgaa ccttttttct
      661 tatccgaaaa ccttactaaa gtatataatt taggaagtca atcctgtatg ataatgtttg
      721 tactatcgtc gagtttttgc ttgattgcct aacgagataa attttagaag aattttcggt
      781 gtgatttgac aagcttctga ctggaaggat agttacacta gtattgttta ttaaaatgag
      841 cagatagaga aaatttggaa tctatttgct tattatcaat cgttttttta gcttatttgt
      901 cttagattgg tatagaactg agctatggat taatactctt gtatcttatc ctgttcctaa
      961 atatgttggt agaaaaatga agcagttgtt acgagtgtct gtattggaaa aaattttgtc
     1021 tatagaattc tttaaatgat atgaaggcta ggaatgccaa agcactgaca tatttcgttt
     1081 gaatctcatc cgctctcttt acttgtattt gtagaaatgc tatcagtaat atattcgcga
     1141 acactatgat ttacaacagt gtggtcgtac atctttgtaa ctttattata caacaaccat
     1201 ttacaggtgt aaagttgagc agtgtcttta gtaaatttag ggatttgttt tgtcatagtt
     1261 ttgatacctg tattcgttgt ttcatgagca tttgacgttt cttttcatgt aggcatttca
     1321 acaattagaa tgatattttt ccgaggatga acttatatat tgtgactttt tagagttatg
     1381 atgcctcttg atttgactat cgctatcaat ttcatccact tttacagttt catggtttta
     1441 tgaaccgaaa catctaggta caggttttag catcaattga ttgtttttga gccatatgaa
     1501 gttgaaacgt ggagatgctt ttcttgtgat aacgccctat tcaaagagga ataaccgttt
     1561 ttggagagag ttcagtacta tgtggcgcta aatactatat gtaaaacata tattaaacaa
     1621 gatttaacta aggagaattg taaaaacaaa aatgagaatt tcatataaag tttattctag
     1681 gagtatgtat cttgaataaa aattgttatt taagttctgg gggttatgat gaatgttttt
     1741 ataataataa aatgcagcta gaagaaaagt tattttaata taaatcactc aacatagcga
     1801 gaaggcggtt tcctatatgg aagtcgtctt gttttcatat tgtctaaata cgagatatct
     1861 actacaggtt atagttgatt taaacaggtc tatagatttc taatatatta aggtgaaata
     1921 atatcttgta atacattgct atgttctatg aaaaaagcga cgatagctaa tgcacaagct
     1981 cctatacttc cacgatgttt gttgtaaggt aaaatttcaa tttctatatt acgagtaaag
     2041 ggaacgaagt ggagctggtc ttggatttta tccctgactt catgagtgaa aggttgataa
     2101 ttaagcaatt gactgttgat atagatttta tcagcaggat tgatgaggag gagatttgca
     2161 atagaagtgg ctaataaatt gactccttta tcaatttgtt gacgtaaagc ggagtcgcct
     2221 aaattataag ccgttaaaag ggtgtctaaa tgaatgtctt tttcagtctt tacaaggctt
     2281 tttagtacag ttagttggga atttttaaat aataattggg cgtgtttgat taaccaagca
     2341 tccgaaatat atgtttgtaa acaacctttt tttccgcatt cacaatattg cccattcaat
     2401 tcgacaatgg tgtgtccaat ttctccgata taaggatttt tagaggctcc tattttttct
     2461 tttgtgaaaa aggaagtgta aatacctaat ccagcgtgta ggaaaataaa gttatcgggg
     2521 gtattgtgtg gattaaaaag gtattgtcct atagccatac aatcgatatt attttttaca
     2581 ataaaaggaa aattgaatct tttaattaca tttaataaat taaaagattc ccatatgggg
     2641 ttgtttgtaa tgatacttcc ggagtctttg ttataatgtc caggtattga taagccaaat
     2701 ccaagtaatt ttgtttccaa agggacgtac tctatagctg tttttatcat attggtaatg
     2761 gtggaattga tttctgaaat aggataatct tcattcaaaa tttctgtctc gaaaagagtt
     2821 ttcccttgta agtcacatag actgagaaag atacctagga cgtttatttc aatacctcca
     2881 acaacatacg gaatattatc tgtgatagaa atagtttttc tacgtcttcc agatccggaa
     2941 aactcgctaa attcatcacc agtttcgtat atgagggact gttcgcttag ctcttttatg
     3001 atgttagtcg ttgttgctgg agtaagtcct gtttcattaa caatatctgt acgggatgtt
     3061 gctggatttc gatatagaaa ctccagtata gtggctctat tttgtaaaaa ggctgattgt
     3121 tttgtaatca tttgtttcct cctttggttt attttatatt aaacataaga aaaaatcaat
     3181 taaaattatt attctataca aagaaaaaaa tattgtaaaa acaacaaaaa atatattgac
     3241 aacgctttct gttagtggta tatttaattt ataaaaaata aaaaaaggag ttccggtgat
     3301 gaacaatatt ttagcgtttt tagaaacaaa agtcgctccg tttggtgaaa aagttggcaa
     3361 ccaacggcat ttgaaagcta ttcgtgaagg atttatgatg gcaatgcctt tgattttagt
     3421 cggctcttta tttcttattc taatcagttg gcctcaagag gcttttacaa attggctgaa
     3481 tagtgttgga ttgctaagta tcttgacaac tatgaatcag tcaacagtag cgattatctc
     3541 cttggtcgct tgtttcggta ttgcctacag gttgtcggaa ggatatggta cagatggtcc
     3601 gtcggcaggg atcatagcct tatccagttt tgtattgatg gcacctcgtt tttcgagtat
     3661 ggtttatgat aaaaatgggg agcaggtcaa gcagttattt ggcggcgcaa taccattttc
     3721 tagcctgaat gcatcttctt tgtttatggc gattactatt ggattggtta cagcagagat
     3781 ttatcgtatg tttatccagc gcggaattac gataaaaatg ccaagtggtg tcccagatgt
     3841 agtaagtaaa tcattttcag ctcttttatc tggttttact acttttgttt tgtgggcttt
     3901 ggtcttaaaa ggtcttgaag cggcaggagt tgcaggaggt ctcaacggac tcctaggtgc
     3961 aattgttgga acaccgctta agttaattgc aggaacgctt ccaggtatga ttctatgtgt
     4021 tattgtaaac tcattctttt ggttctgtgg agttaatggg ggacaagttt taaatgcttt
     4081 tgtagaccca gtttggttac aatttactac agaaaaccaa gaagctgtgg ctgcaggaca
     4141 aacactccaa cacattatta cattaccgtt taaagattta tttgtattta ttggtggcgg
     4201 tggagcgact attggtcttg cgatttgtct cttcctattt agtaagagtc gtgcgaataa
     4261 aacattaggt aagctagcta ttataccgtc tatttttaat atcaatacag ctattctatt
     4321 tacgtttcca acagttttaa atccgattat gctgattccg tttattgcta ctcctacaat
     4381 caatgccttg attacctatg tatcaatggc tgtaggatta gtaccctata caacaggtgt
     4441 aatccttccg tggacaatgc caccgattat aggaggcttc cttgcaacag gggctagttg
     4501 gcgaggagct ctattacaag ttgttttgat tttggtttct gtagcaattt attatccatt
     4561 cttcaaaatt gcagataaac gcaatcttga aaaagaaaaa gctactgttg gagggaaata
     4621 agatggttat cagagtattt gatcaacaga aaaatactta ttctagcttt gccttagagg
     4681 aattaagtta ctatatgaat cgggtcttta agactaacat agagcttgtc gaggagaagg
     4741 aagcggatat ttttgtagga ttagtcaata aagaggacag aaaagaccat gttcttatct
     4801 cattagacaa gggtaagggg agaattgagt ctaatacaat tgtaggttta cttattggaa
     4861 tttaccgaat gtttcatgaa tttggggttg tgtatactag accagggcgc agacatgact
     4921 ttgttccaga gttacgattt gaagattttt tagataaaca gctatctata gatgaaacag
     4981 ccagttacta tcatagggga gtatgtatag agggagcgga ttcatttgaa aatatactag
     5041 atttcattga ttggctacct aagattggga tgaacagttt tttcatccag tttgaaaatc
     5101 cttactcttt tttgaaacgt tggtatgaac atgaatttaa tccatatcta aataaagaac
     5161 aattttcaaa tgaattagta caagaattga gtgataggtt ggataaagaa ttgcaaaaaa
     5221 gaggtcttat tcatcatcgt gttggtcatg gatggacagg tgaagtttta ggttactctt
     5281 caaaatttgg ctgggaatca ggtcttagta tttcagagga gaagaaaccc tatgtcgctg
     5341 aaataaacgg gaaacgagaa ttgtttaata cggctccgat tttaaccagc ctggattttt
     5401 caaatccaga tgtagctgat aagatggtag aaattatcaa ggattatgcc aagaaaagac
     5461 ctgatgttaa ctacttacat gtatggttgt cggatgctcg taataatatt tgtgaatgcg
     5521 aaaactgtag acaagaattg gtttcggatc agtatattcg tattctcaat caattggata
     5581 gggctttaac gagtgaggga ttagatacaa agatttgttt tctgctttat catgagttgt
     5641 tatgggcacc tcagaaagaa aaattagata atcctgaacg ctttaccatg atgtttgcac
     5701 cgattacaag aacatttgaa atgagttatg cagatgtaga ttttgacaat tccataccta
     5761 cgcctaaacc ttatatgcgt aataaaatta tacttccgaa ttctcttgag gaaaatttat
     5821 cttatctttt tgagtggcaa aaagcattta aaggagatag tttcgtatat gactatcctt
     5881 tagggcgtgc tcattatggc gatttaggct atatgaaaat tagtcaaact atttacagag
     5941 atgtatctta tctttccaac ctacatttga acgggtacat ttcgtgtcaa gaattacgtg
     6001 ccggattccc tcataatttt cctaattatg tcatggggga aatgctctgg aagaagacaa
     6061 gaagttatga agaattgatt gaagaatact tttctgcttt gtatggggaa aattggcagt
     6121 ctgttgttga atatttagaa aaattatcca tttattcctc ttgtgattat tttaatgcaa
     6181 ttggcagccg tcaaagtgat gttttagcga atcattatta tatagcttac aatctagctg
     6241 ataatttttt accaattatt gaggaaaata tttctaagtt attaaatagt caaaaggatg
     6301 aatggaaaca gctcagttat catcgtgaat atgttgttaa gatggcgaag gctttatatc
     6361 ttcaagcaac tggaaaaaca aggcaagctc aagatgaatg gagaaatgtg ttgaattata
     6421 tccgtgggca cgaattgcta tttcaatcta atttggatgt ttatcgtgta attgaagtag
     6481 caaaaaatta cgctggtttc cacttataaa tcataagtat agaaaatgaa ctaaggtatt
     6541 cagagaagat tgatcctaaa tattatgaaa tttaaggatt tttaagatat ttagggtcaa
     6601 ctttctattt atatcgtagc gaagtcattt taataatgat gtgtaaaaga tggatcaaga
     6661 ttgaggagga agaaagatga aatcaaaaga agaaataaat atgcttggtt ttacaattgt
     6721 cgcttacgca ggagatgcaa ggtcagattt gatggatgct ttggcgtttg cgagagatgg
     6781 atattttgaa caggcaagag aattggttga gtctgcaaac gactcaatag tgtctgccca
     6841 tcgagaacag actaatttat tagcggagga ggcatatgga gataattttg aagtgagctt
     6901 tattatgatt catggtcaag atactttgat gacaacgatg ctattgtatg atcaggtaaa
     6961 gttttttatt gatgaatatg aacgaattcg aaagattgaa gaacatattg gtttgcaatg
     7021 aggattagtc atggaaaatt tacaggttaa agccttaccg aaggagtttt tattaggaac
     7081 tgctaccgct gcttatcaag tagagggtgc aactagggta gatggcaaag gaataaatat
     7141 gtgggatgtt tatttgcaag aaaatagtcc gttcttacca gatccagcta gtgattttta
     7201 ttatcgttac gaagaggata tagctttggc ggcagaacat ggtttgcagg ctttgcgttt
     7261 atctatttct tgggttcgta tatttcctga tatagatggg gatgctaatg tattagctgt
     7321 tcattattac catagagttt ttcagtcttg cttaaaacat aatgtgattc cgtttgtttc
     7381 tttacatcat tttgattcgc ctcagaaaat gttagaaaca ggggattggt tgaacagaga
     7441 gaatattgat cgtttcatac gatatgctcg cttttgtttc caagaattta cagaagtcaa
     7501 gcattggttt acaatcaatg aactgatgtc tcttgctgca ggtcaatata taggaggtca
     7561 gtttcctcca aatcatcatt ttcaattatc tgaagcaatt caagcgaatc ataatatgtt
     7621 gttggcgcat gctcttgcag tcctcgaatt tcatcaatta gggattgagg gaaaggtagg
     7681 ttgtattcat gctttaaagc caggctatcc tattgatggg caaaaagaaa atattttggc
     7741 agctaaacgg tatgatgttt ataataataa atttctatta gatggaactt ttttgggcta
     7801 ctacagtgag gacacgcttt ttcacttgaa tcaaatattg gaagctaata attctagctt
     7861 tattattgaa gatggtgatt tagaaattat gaagagagct gcacctctta atacgatgtt
     7921 tgggatgaat tattatcgtt cagaatttat tcgtgaatac aaaggtgaaa atagacaaga
     7981 atttaattca acaggaataa aaggacagtc ttcttttaaa ttaaatgctc taggtgaatt
     8041 tgtaaaaaaa cctggtattc cgacaacaga ttgggattgg aatatttatc ctcaagggtt
     8101 atttgatatg ttgcttcgta tcaaagaaga atatcctcaa catccggtca tttatttaac
     8161 tgaaaatggt acagccctta aagaagttaa gccagagggc gagaatgata ttattgatga
     8221 cagtaagaga atccgttata ttgagcaaca tttacacaaa gttttagagg ctcgagatag
     8281 aggagtcaat attcaaggct attttatatg gtctttgcaa gatcaatttt cttgggcgaa
     8341 tggctacaat aagcgatatg gtcttttctt tgttgattat gaaacacaga agagatatat
     8401 taagaaaagt gctctttggg taaaagggct aaaacggaat taaggttagc gatttgactg
     8461 atgtttaata tgttttaaat atgaggttga attttttata ggaggagttt tatggataag
     8521 ctagtcgctg ccattgaaaa gcaacaaggg aaatttgaaa aaatttctac taataactat
     8581 atgatggcta ttaaagatgg attcattgct actatgcctt taattatgtt ttcaagcttt
     8641 ttgatgatta ttattatgat tcctaaaaat ttcggagtag agttaccgag tccagctatt
     8701 gtctggatga gaaaagtgta tatgttaacc atgggagttt tgggtattat tgtttcaggg
     8761 actgttggaa agtcattagt tggaaatgtt aacagaaaaa tgcctcacgg aaaggtaata
     8821 aatgatattt ctgcaatgtt ggcagccata tgtagttatc tggtattaac tgtaacgctt
     8881 gtagttgatg agaagacggg atctacaagt ttgtcgacaa actatttagg atctcaagga
     8941 ttgataactt cgtttgtcag tgcctttatt actgtaaatg tttaccgatt ctgtattaag
     9001 cgagacatta ctattcattt acctaaggaa gttcctgggg ctatatcaca agcttttaga
     9061 gatattttcc ctttttcttt tgttttactt attagtggtt tgttagatat tgtatctcgg
     9121 tttagtttag atgttccttt tgcccaagta tttcaacaac tattgactcc tatttttaag
     9181 ggggcagaat catatcctgc tatgatgttg atttggttta tgtgtgcttt gctttggttt
     9241 gttggaattc atggaccatc tattgtctta cctgctgtta cagctttgca actgagcaat
     9301 atggaagaga atgctcaact tcttgcaaat gggcagttcc cttatcattc tttaacacct
     9361 aatttcggga attatatcgc tgctattgga ggaacggggg ctacctttgt tgtaccattt
     9421 attttgattt tctttatgcg gtctaaacaa ttaaaatcgg taggtaaagc tacaattact
     9481 cctgttttat ttgcggtaaa tgaacctctt ctatttggta tgcctgttat tttgaatccc
     9541 tatctttttg tccctttttt gatgactcca ccagtgaatg tatttctagg aaaggtcttt
     9601 attgatttct ttggaatgaa tggattttat atccagttac cttggacctt tcctggtccc
     9661 ttgggattgt taattggaac gaattttcaa cttatctcct ttgtattttt atctttgatt
     9721 ttagttgtcg acatattgat ttatttgcca ttctgtagag cgtatgatag acagttactg
     9781 gtgaaagaag atattgcaag ctcaaatgat attattttag aggaggatac aagtgaaata
     9841 attcctggtg agatagatga aataaaaagt aaggagttga aagtactggt tctttgtgca
     9901 gggtctggaa caagtgcgca attagccaat gcaattaacg agggggctaa cttaacagag
     9961 gttagagtga ttgcgaattc aggagcgtac ggagctcatt atgatattat gggtgtttat
    10021 gatttaatta ttctggcccc acaagttcgg agttattata gagagatgaa ggtggatgca
    10081 gaaagattag gtattcagat agttgctacc agaggaatgg aatatattca tttaacaaag
    10141 agtccaagta aagccttaca atttgtattg gagcattacc aagctgtgta gtaagttttt
    10201 ccatctttta tttgagtaaa gattttgttt acagataggc ttggatttaa aaacgttccc
    10261 ccttttttaa tataagaatc cctctttcac aattgtaaaa agagggattt tgtattttat
    10321 ctcttagacc aagttctctt cataaagaga aggaggattg ggtaaatctc caagcgccct
    10381 gcaatcattg caaaggatag gagaattttt gagatgggac taaagattga gaaactagaa
    10441 gtggttccta gaataggccc gatattattg aaacagctaa agacagcgct ggtcacgacc
    10501 agaaaatcat tgctatctag gctgacaata aagataagcg ctagcaaaat catagcatag
    10561 atgacaaagt acttgagaat cttatgctgg gtatctttgt caatcaccgt tttattaaca
    10621 tggagggtca aaacacggtg gggcgatagg attgacaaaa tttggttttt ggcaattttt
    10681 gaaaggatga ggcctcgaat aatcttgagt ccacctgcag ttgatccagc agagccaccg
    10741 attgccatga ggaaaaggag gataaactgg gagaagaggg gccagttggt aatatctcca
    10801 tatccaaaac cagttgttgt aatgatgttg gaaacctgga agaaggtcat ttcaaagctc
    10861 tttgaaaacc ctgggtagag gtagagggtg ttgaggctaa tcaagcctgt agaaaccagt
    10921 acaatgacca agtaagccct aagctcttca tctccaaaga aggccttgat gcgacggagc
    10981 atgaggtagt agtagaggtt gaaatttact ccaaaaacca gaactccgat actgaccaga
    11041 taggtaatca gtgagctgcc atagtgggca attccgtcgt tatagacggt aaagcctcca
    11101 gttcccgctg tccccatagc aataacaaaa ctatcgtaga gaggcatacc ggctagataa
    11161 tagatgatga caaagaggga gaagagagct agataaagga gatagagaat ctgggcagtg
    11221 ttttttagtt tggatacaac cttgccaaaa acaggacctg gaacctcagc cttcatcacc
    11281 tctaggtggc tatttttggc attgtccata atagcaagtg caaaaacaag cactcccatc
    11341 cctccaatca agtgggtaaa acttcgccag aagaggaggg aacggctgag aaccgaaacg
    11401 tcgttcaaaa tacttgctcc agtagttgta aatccagaac taatttcaaa aaaggcatca
    11461 ataaggctgg ggatttgccc agaaaagaca aaggggagac caccaaagaa agaccaaagg
    11521 atccaacaga gggcaacgat caagactccc tccttggcat aaatccgttg attttttggc
    11581 ttctgtaaac tccctgaacc gcctaacaat acgagaatcc ctatggtcga aaagagggct
    11641 gtaaagactt ggctcgattc acggtaatag acagcaatcg caacaggaac caaaagaaga
    11701 acagcttcaa tcaaaagtaa ttttgaaagg aggtaacgaa tcatactttt attcatttct
    11761 tacctcgcga tcaagtcata aatcttggtg atgtttggca acaaggttgt tactaggagc
    11821 ttgtctccaa cttccaacat atcctcccca gttgggaaaa tagtcttgcc ctttcgaata
    11881 atggctgcaa taagaacccc ttttttcaat ttcagttgag aaagaggttt ggcagtcatt
    11941 ttattggctt ccttgatatg gaattgcagg gtttcgattt ggccattggc tagatggtgc
    12001 atagcttgaa ggtctgaata ctgggcatta actcgaccac gaataaagtg cataatcgta
    12061 tctacagcga tgcttttagg tgtgatgata cttgaaaaat caggcgcatt gataatctcg
    12121 aggagactgg tacgattgac cttagtaata tttttctgta cacctaccct gtcaaggaac
    12181 atagatgtaa tcagattttc ctcatcgact cctgttagag tcgcaacggc atcatagtgt
    12241 tgagcacttt cttccagcag gatatctttt gcggttccat ctccttgaac gatgtagaga
    12301 tttgggaatt tctcgctaaa gaagctggcg atttcaggat tgatttcaat gacttttgta
    12361 tcgatacgac tatctttgag aataccaagt agataatagg caattctacc tgccccaacg
    12421 atgagaaggc tcttcacggc gcgtgattta aaataattat ggaagagtat catatcgaca
    12481 cggttaccag tgacaaagat tctatcttta tcctgtacag tcatgtcacc gcttggaatg
    12541 ataatttgat gatccctctc tatcgcacag acaatgacat taccaaattt tttacgaaaa
    12601 tcagaaatgg gcatttggca aagaccgctg gtggacttga cgacaaattc catgaggcta
    12661 acgcgtccac cagcaaagcg ttcgacagac agggcgttgg ggaagtcaat gatattcgcg
    12721 atagcgcggg cagccaagag ctcaggatta acgataagag aaaaaccgag aatattcttt
    12781 tccttgaaat aagagttaga atattcaggg ttccgcaccc gaacgatagt ttctttagct
    12841 cccattttct tggctagaac tgctgcaatc atgttgactt catcgtgctc agtcagggcg
    12901 ataaagatat cacaatcttg gacgctggct tgctcaagaa tggcaaaatc ggccccgtta
    12961 ccaaggatac caatgatatc aaagcgactg acaatatgat tgagaacagc ttcgtcttgc
    13021 tcaatcagca aaacatcatg cttttctgca accaaggagc gacagagggc aaaaccaact
    13081 tttccccctc cgacaaggat aattttcata ataaaaccta ctttttcatg atgtaactat
    13141 catacccttt ttcaagaaaa aatgcaccta ctagctaata acaagagttt ttagtgaaaa
    13201 ttcgctataa ggtaaaacta taccctaacc aattgaaata gctattagcg actttctctg
    13261 aaatatggta tgataaagga tatacaagga gataaaatga ataataattt actggtatta
    13321 caatcagact ttggtctggt tgatggtgcg gtatcggcta tgattggagt ggctttagaa
    13381 gagtctccaa ccttaaaaat acatcacttg acgcacgata tcacgcctta taatattttt
    13441 gaggggagct atcgtctctt tcagacggtg gattactggc ctgagggaac gacgtttgta
    13501 tcggttgtcg atccaggtgt cggttcgaaa cgtaagagtg tagttgccaa gactgcaaaa
    13561 aatcaataca ttgtcacgcc agataatggg acgctttcct ttatcaagaa acacgttggc
    13621 attgtagcca ttcgtgagat ttctgaggtg gccaataggc gtcaaaacac agagcattct
    13681 tataccttcc acggtcgtga tgtctatgcc tatactggtg ctaaactggc cagtggtcac
    13741 attacttttg aggaagtagg gccagagctc agtgtggaac agattgtaga gcttccagtc
    13801 gtagcgacca tcatagaaga tcatctggtg aagggagcca ttgatattct ggatgtgcgt
    13861 ttcggttcgc tttggacctc tatcacacgg gaagaatttt acaagctgga accagaattt
    13921 ggtgatcgtt ttgaagtgac catctatcat gctgatatgc tggtctatca aaatcaggtt
    13981 gtctatggca aatcatttgc agatgtgaga attgggcaac ccatccttta catcaactct
    14041 ctctatcgtt taggtttggc tatcaaccaa ggttcctttg ccaaggccta taatgtaggt
    14101 gtcggttcat cttggaccat tgaaataaag aaaatagaag gataaaatag gagaatagta
    14161 tggaaatcaa atttacaatt aaacaagttg ttgctgtcgg aattggcgct gccctctttg
    14221 tcgtcatcgg gatgatcaac attccaaccc ctgttccaaa tacaagcatc cagcttcagt
    14281 atgcggtaca agcgctactt tctattattt ttggaccgat tatcggtttg cttgtcgggt
    14341 tgattggtca tgcaatcaag gactctcttg ttggttatgg tctatggtgg acttggatta
    14401 tcgctagcgg actctttggt ttagttgtgg gactttttag aaagtacgtt cgcgtgatca
    14461 atggtgtttt tgactggaaa gatattctta tttttaatct cattcaacta cttgcaaatg
    14521 cccttgtttg gggtgtcttg gcaccacttg gagatgttgt gatttatcaa gaagcggcag
    14581 aaaaagtatt tgcacaaggg attgttgcgg gaattgccaa tggtgtatct gtagctattg
    14641 caggaactct tctcttactt gcctatgcag gaacccaaac tcgtgcagga agtttgaaaa
    14701 aggactaata ctcaatgaaa atcaaagagc aaactaggaa gctagccgca ggttgctcaa
    14761 aacagtgttt tgagattgtg gatagaactg acgaagtcag ctcaaaacat ggttttgagg
    14821 ttgtagatga aactgacgaa gtcagtaacc atacctacgg caaggcgaag ctgacgtggt
    14881 ttgaagagat tttcgaagag tataaaatga tggggaaggc tgggcaacta gtctttttcg
    14941 atgtttatag attagttagg caagtaagct aggataggaa tctttttggc gctaagattt
    15001 taagaggaga gactgcaaga agggcttgat ttatgataaa atagaagtct aagaagcgaa
    15061 tgaagagagt aagatgaaag aagctataat tgagtggaag gatttctctt tccggtatga
    15121 aacacaacaa gaaccgacct tgcaagggat agacttgacc atttacaagg gagagaaagt
    15181 cttaattgtt ggaccatctg ggtcaggtaa atctaccttg ggtcagtgtt tgaatgggat
    15241 tattcccaat atttacaagg gtcagacata tggagaattt ttgataaagg gtcaagtagc
    15301 ctttgatatg agcatctatg ataagtctca tctggttagc acagttttgc aggatacaga
    15361 tgggcagttt attggcttgt ctgtggcaga agatttggcg tttgctctgg aaaatgatgt
    15421 gacagcccta gatgagatga aaggtcgtgt ttataaatgg gctgaaaagc tggaccttct
    15481 tcctttactg gatcagcgtc ctcaggattt gtcaggtgga caaaagcagc gagtcagtct
    15541 ggctggtgtc ttgattgatg aaagtccgat tctcttgttt gatgagccac tcgccaatct
    15601 agatcccaag tcaggtcagg atattatcga attgattgac cagattcata aggaagaggg
    15661 gacgacgact cttattatcg agcaccgttt ggaggacgtt ctgcatcgcc ctgtggatcg
    15721 gattgtcttg ataaacgatg gtcgtatcct ttttaatggg agccctgacc agttgcttgc
    15781 gactgattta ttgactcaaa atggaattcg agaacccctt tatctaacga ctctccgtca
    15841 attaggtgtg gacttagtca aggaagaaca attagcgaat ctggataact tgtctatctc
    15901 aaaaggtcag gttcagttgc agaatgaact ggcaaaagaa accccagcat tgcagtcact
    15961 ctttagacta gaggaagtat ctttttctta tgatgataga ccgattttaa aatccctaca
    16021 tttagatatt aaaaagggtg aaaagattgc tattgtcgga aaaaatggag cagggaaatc
    16081 aactctagcc aaggctataa gtagctttat tcagacggaa ggacgctatc tttgggaaaa
    16141 acaggatata aaaggcgatt ctgttgcaga gcgggcggaa cgagtaggat atgtgctaca
    16201 aaatcctaat caaatgattt caaccaatat gatttttgat gaggtggctc tagggctccg
    16261 tttgcgaggt gtggatgaga aggaaattga aacgagagta tatgaaacct tgaaaatctg
    16321 tggactttat gaattccgta attggcctat ttctgccctg tcatttggtc agaaaaaacg
    16381 tgtcaccatt gcttcaattt tggtcttagg agctgaaatt attctcctag atgaaccgac
    16441 tgcaggtcaa gatcagaaga actatactga gattatggaa tttctcgaag agttacatca
    16501 aaaagggcat accattgtca tgattaccca tgatatgcaa ttgatgctgg attattcaga
    16561 ccgggtcctt gtcatggtgg atggagaatt gattgccgat actgttccag ccagtctgtt
    16621 gagcgatcct gagctgttag taaaagccaa tctaaaagaa acctccatct ttaacttggc
    16681 taagaaacta gatgtggatc cactggattt aacggcattt tacaaagaaa ggagagaggg
    16741 atgcaagcta aattaatcgg ttaccagcat agagatactg tgattcatcg cttgtcagga
    16801 gctgggaaac ttctcttttt cattctggta tcattggcgg ccatgattag ctatgatacc
    16861 agaatgctct tgctgattgc catcttttca gtctttctcc tctatttatc agaaattcgc
    16921 tttaaagatg tttcctttgt agccgttttt gcgacgatat ttgccgtttt aaacgttttg
    16981 atggtctatc tcttttctcc cgagtatggg gttggacttt atggagagag aagtgtgatt
    17041 tggcagggaa tcggtgtcta cactctaacc agccaggagc tcttttatct gctaaatttg
    17101 gccattaagt atctttgcac cattcctctg gctattatct ttttgatgac aacccatcct
    17161 agtcagtttg cttccagttt aaatcaaatt ggtgtgccct ataagattgc ttattctgtc
    17221 agcctgacct tgcgctatat tccagatttg caggaagaat tctttactat caagatgtct
    17281 caggaggcgc gtgggatgga attatccaag aaagcttctc ttatgcaacg aatcaaaggc
    17341 aatctgctca ttattacgcc cttgattttt agctcgctag aacgcattga taccattgcg
    17401 actgccatgg agcttcgccg ctttgggaaa gagaaaaaac gcacatggta tagttatcag
    17461 gccttgaaaa aaggagacta tattaccttg ctcttggcaa ccttgttttt agtagttagt
    17521 ttactactta tcttgcagaa tcagggacga ttttacaacc cttggaaata gcttgaaaaa
    17581 attgaaaaaa tcaagtcatt tctattgaca atgattctga aagtgttata ctaagaaagt
    17641 agtttcgctg atttacttca aacctgttgt gaggtaagtt aacgatgcct taaccacgct
    17701 gtttgctgag cttgactccg ggcagtgtgg ctattttttt gcaatggtga aaggaagcaa
    17761 gtcatgacaa atcacattgt attatttgaa cctcaaattc cacaaaatac gggcaatatc
    17821 gcgcgtactt gcgctgcgac caattctccc ctccacatca tcaagcctat gggctttcct
    17881 attgatgacc gcaagatgaa gcgggctgga ttggattact gggataagct agagatttat
    17941 ttttacgaga gtttggaaga tttcatatct cagatgaagg gaaaactcta tctgatttcg
    18001 aaattcgcgg aaaaagtcta ttctgaggtg gatttatcga ctgacgagga ccattatttt
    18061 ctctttggac gtgaagacaa gggcttacct gaagatttta tgcgagaaca tcctgagaag
    18121 gctctccgta ttcccatgaa tgatgaacat gtccgcagtc tcaatgtgtc taataccgtc
    18181 tgcatgattg tctatgaggc tcttcgccag cagaactttg caggtcttga gctcgtccat
    18241 acctatgaag tggataaatt gaaataaaaa atgaaaatga acaaaatgct tgcgcttgca
    18301 agcgtttttt gttatgataa aagagtcttc agggcagggt gaaattcccg accggcggtg
    18361 actttaacta ggaaatgatc ttttcctttt atactttgtt gacaagcttt gcctaaccag
    18421 aagttatgcc tacagcttgt cgcctagtct aaaagaaaaa tctctatttc cttctcttta
    18481 aagaagtccg tgagcgcaag ctgatgtggt gagattccac aaccgacagt atagtctgga
    18541 tgggagaaga cgaaagaata gccttgtctg ttttgataga tttatagccg gattgtaacc
    18601 acttgctttg tttttcttta atagagtaag agggaacttt tgggatataa aaagtgagaa
    18661 tagatagagg aatcctttcc aacttcttct gattttatag aaaattggag gaacctgtta
    18721 tgacaaacac acgtcgactt tcgaccattg caattctatc agccatctca tttgtgctga
    18781 tgtactttga ctttccgctt ttaccagcgg catctttcct caagatcgaa tttagtatct
    18841 tgccagtcct tgtgggtctg gtggtcatgg atttgcctgc tgctctagga gtgctcttgc
    18901 ttcgctcact cttgaaattg cttcttaaca gccaaggagt gaatacttac attggtttgc
    18961 cgatgaatat cgtagctttg ggagtttttg tcatcgtatt tgctttgatt tggaaaaagg
    19021 aacggacaac ccttcgtttc ctactaggct ctctagctgg aactattggt ttaaccttgg
    19081 ccatgttggt tctcaactat gtttatgctg ttcctttgta cgctaagttt gctaactttg
    19141 atattggaaa aattttggga ctttccaact acctaatgac catggtatta ccttttaact
    19201 tgattgaagg tgttatcttt tccgtttcat tctggttgtt gtatgttctc ttgaaaccaa
    19261 ccttaaaaca ttatgagaga taaacaaaca tttttaatga agggcagttt tgccctttta
    19321 cttttcgtta ttcttggcta catggtcaaa ttttaccctg aaatgttggt caattttgac
    19381 caatcgattc agactgccat tcgaggagac ttaccagatt atttgactat tctttttcga
    19441 gccctcacac gtctgattga tatcccagtg attatcactt gggttgtcat tacagctttt
    19501 gtcttttatc gtaagcgatg gaagatagaa agtttcttca tgctgggaaa tctggctttg
    19561 gcaggtcttt taatcgtgac ctttaaaaat atctaccagc gcccacgacc agctatttta
    19621 catctggtgg aggagaaggg attttccttc ccaagtgggc attctctagc tgtaacgctg
    19681 atggtaggga ctttgattgt tattcttagt cagcggatta aagatcaggt ctggagaaaa
    19741 atcgtacaaa tcgtccttgg cctctaccta gtcagtgtgc tggtatcaag agtctatctg
    19801 ggagttcatt acccatcaga cgtccttgcc agtctctgtg tgggcttggg agtcctgttt
    19861 atcgagtttc ccttttatga caagctccgc ttccaatggc gatttaaagg caaacagaag
    19921 tgagtatcga attcccttga ggagaaagaa atgaaagtca atatagcaga tcttcatctg
    19981 actcaactat atttatcaga aaagaagttg caagatattc agatgcttta ccagtcggca
    20041 gaaacaatcc aagtcgatcc aatcagtatt cttgcctttg gagattgttt gctgattaca
    20101 gatgggcatc acagggctta tcaggcttta ttggcaggtc gggatacgat ttctgctgag
    20161 tgggatagag atggtggtga tgaactatat catctctatg cgcaagcttg cgaggaaaga
    20221 aagatttact ctgtttttga tttagaagat cgtatcctag ctcaagatgg gtatgaagca
    20281 aaatggtata actggtgtga tggttttaat caagcagcaa ctcttttgtt gaaaaggtag
    20341 tgcattgtgt tttgttcctt attataaggt caatcattgt gaggaagctt ttgcttggta
    20401 tcaggatgtg aacttggttt acctcgtaga tggggtgaag cttccttaca gtcaagcgac
    20461 cttggaagcc atgtattcct atttggatcg gcatggtgag cttttttgga ttgaagtcaa
    20521 ggagaaggga gaatggtttc caattgggga tattacacta tctcaggata atctccccat
    20581 tgtgattggg aattccgctt accaacatcg aggacttgga aaaaagattc taagtgcttt
    20641 gattgaattg gctcgagtaa aaggatggaa agaattgaga gtcaagaaaa tctacaccta
    20701 caatcatgct tctaggaggt gtttcaagtc gcttggattt gtggaaaatg gagcaacaga
    20761 aaaaggaatg agttttatat tggaattagt ctaatcctgc cactttctcc cccttaacct
    20821 ttgactattc cgcaaaatta tcgtaaaata aagagtaaat gataaaatga ggtcagagtc
    20881 tgttcgctct ggcgatagta gtataaatga ggagaaacgc tttggaatta gaagtatttg
    20941 ctgggcaaga aaaaagtgaa ctatctatga ttgaggtagc gcgtgctatc ttggaacttc
    21001 gtggtcgcga tcatgagatg cattttagcg atcttgtaaa cgaaattcaa aactaccttg
    21061 gaacatcaaa cagcgatatc cgcgaagctt tgcctttgtt ctacacagag ttgaactttg
    21121 acggtagctt catctcactt ggggacaaca aatggggtct tcgttcatgg tatggtgtgg
    21181 acgaaatcga cgaagaaatc atcgctcttg aagaaaatga cgacgatgaa gtagcaccaa
    21241 aagctaagaa aaaacgtgtc aatgccttta tggatggtga ttcagatgcc attgactaca
    21301 atgcagatga tccagaagac gaagatgcat acgaagcaga tccagctctt tcatacgatg
    21361 atgaaaatcc agatgatgaa aaaaatgaag tggaagctta tgatgcagaa atcaacgaaa
    21421 tcgctccaga tgacttggga gaagatgtgg atctcaacga agacgacgac gagttttcag
    21481 atgacgatgc tgaaaccagc gaggaataag agttagctat tgacaattat cctattttta
    21541 ggtatcatat tgtttgggca cctcttttag aggtcggggc tccctagttc ttagggagct
    21601 atttttgttt tttcaagaag ttatcttctt gtattttata ctcaatgaaa atcaaagagc
    21661 aagctaggaa actagccgta ggctgctcaa aacactgttt tgaggttgta gataagactg
    21721 acaaagtcag gaacacatat ctacggcaag gcgacgttga cgcggtttga agagattttc
    21781 gaagagtatt agttgtgaat ctggtgcagt cgtcccagat tattcttatt agtagggtct
    21841 tgttttctat atcccctcgt agttaacaag accttgagca ttttagaaag aggaatctat
    21901 gtctacgaaa tatatttttg taactggtgg tgtggtatcg tccattggga aagggattgt
    21961 ggcagcgagt ctaggccgtc tcttgaaaaa tcgtggtctc aaagtaacca ttcaaaagtt
    22021 tgacccttat atcaatattg atccgggaac catgagtcct taccagcacg gggaagtttt
    22081 tgtgacagat gacggagctg agacagattt ggacttgggt cactatgaac gtttcatcga
    22141 tatcaatctc aacaaatatt ccaacgtgac aactgggaaa atttacagtg aagttcttcg
    22201 taaagaacgc cgtggagaat accttggggc aactgttcaa gtcattcctc atatcacaga
    22261 tgctttgaaa gaaaaaatca agcgtgccgc tctaacgacc gactctgatg tcattatcac
    22321 agaggttggt ggaacagtag gagatatcga gtccttgcca ttcctagagg ctcttcgtca
    22381 gatgaaggca gatgtgggtg cggataatgt catgtatatc catacaacct tgcttcctta
    22441 cctcaaggct gctggtgaaa tgaaaaccaa accaacccaa cactctgtca aagaattgcg
    22501 tggcttggga atccaaccaa atatgttggt tattcgtaca gaagagccag ctggtcaagg
    22561 aattaaaaat aaactggccc agttctgtga tgtggcacca gaagccgtta tcgaatcgtt
    22621 ggatgttgaa cacctttacc aaattccact gaacttgcag gcacaaggga tggaccaaat
    22681 tgtttgtgat catttgaaat tagacgcacc agcagcggat atgacagaat ggtcagccat
    22741 ggtggacaag gtcatgaacc tcaagaaaca agttaagatt tcccttgttg gtaagtatgt
    22801 ggagttgcaa gatgcctata tctcagtggt cgaagccttg aaacactctg gctatgtcaa
    22861 tgatgcagaa gttaaaatca attgggtcaa tgccaatgat gtgacagcag agaatgtagc
    22921 agaactcttg tctgatgcgg acgggatcat cgtaccaggt ggttttggtc aacgtggtac
    22981 agaagggaaa atccaagcca tccgctatgc gcgtgaaaat gatgttccaa tgttgggagt
    23041 ctgcttggga atgcagttga catgtatcga gtttgctcgt cacgttttag gtcttgaagg
    23101 tgccaattct gcagagcttg caccagaaac aaaataccct atcattgata tcatgcgtga
    23161 tcagattgat attgaggata tgggtggaac ccttcgtttg ggactttatc cgtctaagtt
    23221 gaaacgtggc tctaaggctg ctgctgctta tcacaatcaa gaagtggtgc aacgccgtca
    23281 ccgtcaccgt tatgagttta ataatgcctt ccgtgagcag tttgaggcag caggttttgt
    23341 cttttcagga gtttctccag acaatcgttt ggtagaaatc gtggaaattc ctgaaaataa
    23401 attctttgta gcttgtcagt atcaccctga actgtcaagc cgtccaaacc gaccagaaga
    23461 actctacact gcctttgtta ctgcagcagt tgagaacagc aattagcaaa atcagaacct
    23521 ttgagaaaaa tctcagaggt tttttgcata cgatgatatt gcagtatatc tgaggtaggg
    23581 gtcctctgta tgtacctgct accgttgaaa tcaatagcga ctccctcttg ccctgtgcta
    23641 gtgaatggat ttatcagtat attgaaatga aataaaattt gaacaaatta attcggaaag
    23701 ccaaatcaat ttctagcaaa gttttaggaa ctggattgta tagtgaattg aaataagatg
    23761 tgaacatctc tatcaggaaa gtcaaattaa tttatagaaa tattttagca gtcaagatgt
    23821 actgttatag attcaataca ttatactttt ttaatttaat ccactatagt aaaatgaaat
    23881 aataacagga caaatcgatc aggacagtca aatcgatttc taacaatgtt ttagaaatag
    23941 aggtgtacta ttctagtttc aatatac
//
LOCUS       DAVFER010000030        23402 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1105170250
            SAMEA2167659-rid19724873.denovo.030, whole genome shotgun sequence.
ACCESSION   DAVFER010000030 DAVFER010000000
VERSION     DAVFER010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2167659
            Sequence Read Archive: ERR388902
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 23402)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23402)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928716.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928716.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 04:07:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,118
            CDSs (total)                      :: 2,073
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 120
            CDSs (without protein)            :: 120
            Pseudo Genes (ambiguous residues) :: 0 of 120
            Pseudo Genes (frameshifted)       :: 67 of 120
            Pseudo Genes (incomplete)         :: 47 of 120
            Pseudo Genes (internal stop)      :: 34 of 120
            Pseudo Genes (multiple problems)  :: 23 of 120
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23402
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2167659-rid19724873.denovo.030"
                     /strain="1105170250"
                     /db_xref="taxon:1313"
     gene            468..1589
                     /gene="mnmA"
                     /locus_tag="VU534_001326"
     CDS             468..1589
                     /gene="mnmA"
                     /locus_tag="VU534_001326"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HEU1513910.1"
                     /translation="MSDNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGIFMKNWDDT
                     DENGVCTATEDYKDVVAVADQIGIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVM
                     CNKEIKFKAFLDYAITLGADYVATGHYARVARDEDGTVHMLRGVDNGKDQTYFLSQLS
                     QEQLQKTMFPLGHLEKPEVRRLAEEAGLSTAKKKDSTGICFIGEKNFKNFLSNYLPAQ
                     PGRMMTVDGRDMGEHAGLMYYTIGQRGGLGIGGQHGGDNAPWFVVGKDLSKNILYVGQ
                     GFYHDSLMSTSLEASQVHFTREMPEEFTLECTAKFRYRQPDSKVTVHVKGEKTEVIFA
                     EPQRAITPGQAVVFYDGEECLGGGLIDNAYRDGQVCQYI"
     gene            1730..2185
                     /locus_tag="VU534_001327"
     CDS             1730..2185
                     /locus_tag="VU534_001327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEU1513911.1"
                     /translation="MTQQDFRTKVDNTVFGVRATALIVQNHKLLVTKDKGKYYTIGGA
                     IQVNESTEDAVVREVKEELGVKAQAGQLAFVVENRFEVDGVSYHNIEFHYLVDLLEDA
                     PLTMQEDEKRQPCEWIDLDKLQNIQLVPVFLKTALPDWEGQLRHIHLEE"
     gene            2195..4108
                     /gene="mnmG"
                     /locus_tag="VU534_001328"
     CDS             2195..4108
                     /gene="mnmG"
                     /locus_tag="VU534_001328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HEU1513912.1"
                     /translation="MTYHFTEEYDIIVIGAGHAGVEASLAASRMGCKVLLATINIEML
                     AFMPCNPSIGGSAKGIVVREVDALGGEMAKTIDKTYIQMKMLNTGKGPAVRALRAQAD
                     KELYSKEMRKTVENQENLTLRQTMIDEILVEDGKVVGVRTATHQEYAAKAVIVTTGTA
                     LRGEIIIGDLKYSSGPNHSLASINLADNLKELGLEIGRFKTGTPPRVKASSINYDVTE
                     IQPGDEVPNHFSYTSRDEDYVKDQVPCWLTYTNGTSHEIIQNNLHRAPMFTGVVKGVG
                     PRYCPSIEDKIVRFADKERHQLFLEPEGRNTEEVYVQGLSTSLPEDVQRDLVHSIKGL
                     ENAEMMRTGYAIEYDMVLPHQLRATLETKKISGLFTAGQTNGTSGYEEAAGQGIIAGI
                     NAALKIQGKPELILKRSDGYIGVMIDDLVTKGTIEPYRLLTSRAEYRLILRHDNADMR
                     LTEMGREIGLVDDERWARFEIKKNQFDNEMKRLDSIKLKPVKETNAKVEEMGFKPLTD
                     AVTAKEFLRRPEVSYQDVVAFIGPAAEDLDDKIIELIETEIKYEGYISKAMDQVAKMK
                     RMEEKRIPANIDWDDIDSIATEARQKFKLINPETIGQASRISGVNPADISILMVYLEG
                     KNRSISKTLQKSK"
     gene            complement(4461..6140)
                     /locus_tag="VU534_001329"
     CDS             complement(4461..6140)
                     /locus_tag="VU534_001329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HEU1513913.1"
                     /translation="MAYTLKPEEVGVFAIGGLGEIGKNTYGIEYQDEIIIVDAGIKFP
                     EDDLLGIDYVIPDYSYIVDNIDRVKAVLITHGHEDHIGGIPFLLKQANVPIYAGPLAL
                     ALIRGKLEEHGLLRNAKLYEINHNTELTFKNLKATFFRTTHSIPEPLGIVIHTPQGKI
                     VCTGDFKFDFTPVGEPADLHRMAALGEEGVLCLLSDSTNAEVPTFTNSEKVVGQSIMK
                     IIQGIEGRIIFASFASNIFRLQQATEAAVKTGRKIAVFGRSMEKAIVNGIDLGYIKAP
                     KGTFIEPNEIKDYPAGEVLILCTGSQGEPMAALSRIANGTHRQVQLQPGDTVIFSSSP
                     IPGNTTSVNKLINIISEAGVEVIHGKVNNIHTSGHGGQQEQKLMLCLIKPKYFMPVHG
                     EYRMQKVHAGLAVDTGVEKDNIFIMSNGDVLALTADSARIAGHFNAQDIYVDGNRIGE
                     IGAAVLKDRRDLSEDGVVLAVATVDFKSQMILSGPDILSRGFVYMRESGDLIRQSQRI
                     LFNAIRIALKNKDASVQSVNGAIVNAIRPFLYENTEREPIIIPMILTPDEE"
     gene            complement(6142..6375)
                     /locus_tag="VU534_001330"
     CDS             complement(6142..6375)
                     /locus_tag="VU534_001330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002947111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-dependent RNA polymerase auxiliary subunit
                     epsilon family protein"
                     /protein_id="HEU1513914.1"
                     /translation="MIYKVFYQETKERSPRRETTRTLYLDIDASSELEGRITARQLVE
                     ENRPEYNIEYIELLSDKLLDYEKETGAFEITEF"
     gene            6655..6870
                     /locus_tag="VU534_001331"
     CDS             6655..6870
                     /locus_tag="VU534_001331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000282487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1513915.1"
                     /translation="MYNLFAFAIGARLVAFIVFVACVYAGNLLFAKLERRQTKFLWKM
                     TFVTLYSLFLLLVTYVVWFVFYFELNA"
     gene            complement(7193..7345)
                     /gene="cibB"
                     /locus_tag="VU534_001332"
     CDS             complement(7193..7345)
                     /gene="cibB"
                     /locus_tag="VU534_001332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000977347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fratricide two-peptide bacteriocin subunit CibB"
                     /protein_id="HEU1513916.1"
                     /translation="MMKDLNNYREISNKELQEIKGGFGVGVGIALFMAGYTIGKDLRK
                     KFGKSC"
     gene            complement(7347..7532)
                     /gene="cibA"
                     /locus_tag="VU534_001333"
     CDS             complement(7347..7532)
                     /gene="cibA"
                     /locus_tag="VU534_001333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000180803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fratricide two-peptide bacteriocin subunit CibA"
                     /protein_id="HEU1513917.1"
                     /translation="MTNFDILDNQFLSLSENELSDIDGGLAPLVIFGVAVSWKAIAGG
                     TALIGSGLAAGYFLGGD"
     gene            7710..8393
                     /gene="tsaB"
                     /locus_tag="VU534_001334"
     CDS             7710..8393
                     /gene="tsaB"
                     /locus_tag="VU534_001334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000865689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HEU1513918.1"
                     /translation="MKVLAFDTSSKALSLAILEDKQVLAETTINIKKNHSITLMPAID
                     FLMASLDWTPKDLDRIVVAEGPGSYTGLRIAVATAKTLAHTLNIELVGMSSLLALVPH
                     QQEGLFVPLMDARRNNVYAGFYENAKPVMAEAHLSFEEVLEKVKGTSQVTFVGEVGPF
                     VEQIQKHLPRTDYKETLPNAANLALLAWDKEADSLHDFVPNYLKRVEAEENWLKNHTE
                     SGESYIKRL"
     gene            8390..8827
                     /gene="rimI"
                     /locus_tag="VU534_001335"
     CDS             8390..8827
                     /gene="rimI"
                     /locus_tag="VU534_001335"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HEU1513919.1"
                     /translation="MIEIKRIQQQPDLAQAIYAVMAAVYLVSPWTLEQIQADLSQDQT
                     WYALAYDGAEVIGFLAVQENLFEAEVLQIAVKGAYQGQGIASALFAQLPTDKEIFLEV
                     RQSNQRAQAFYKKEKMTVIAERKAYYHDPVEDAIIMKREIDEG"
     gene            8817..9827
                     /gene="tsaD"
                     /locus_tag="VU534_001336"
     CDS             8817..9827
                     /gene="tsaD"
                     /locus_tag="VU534_001336"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HEU1513920.1"
                     /translation="MKDRYILAFETSCDETSVAVLKNDDELLSNVIASQIESHKRFGG
                     VVPEVASRHHVEVITACIEEALAEAGITEEDVTAVAVTYGPGLVGALLVGLSAAKAFA
                     WAHGLPLIPVNHMAGHLMAAQSVEPLEFPLLALLVSGGHTELVYVSEAGDYKIVGETR
                     DDAVGEAYDKVGRVMGLTYPAGREIDELAHQGQDIYDFPRAMIKEDNLEFSFSGLKSA
                     FINLHHNAEQKGESLSTEDLCASFQAAVMDILMAKTKKALEKYPVKILVVAGGVAANK
                     GLRERLAAEITDVKVIIPPLRLCGDNAGMIAYASVSEWNKENFAGWDLNAKPSLAFDT
                     ME"
     gene            complement(9873..11173)
                     /locus_tag="VU534_001337"
                     /pseudo
     CDS             complement(9873..11173)
                     /locus_tag="VU534_001337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677188.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(11449..11800)
                     /locus_tag="VU534_001338"
                     /pseudo
     CDS             complement(11449..11800)
                     /locus_tag="VU534_001338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(11907..12200)
                     /locus_tag="VU534_001339"
                     /pseudo
     CDS             complement(11907..12200)
                     /locus_tag="VU534_001339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            12443..13648
                     /locus_tag="VU534_001340"
                     /pseudo
     CDS             12443..13648
                     /locus_tag="VU534_001340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001200043.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
     gene            13641..14516
                     /locus_tag="VU534_001341"
     CDS             13641..14516
                     /locus_tag="VU534_001341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000375706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEU1513921.1"
                     /translation="MDRNIDQELVSIIIPTHNRYESLIRAVKSCLHQSYKNIEVIIID
                     DNYSNVNLRNKIIHQFGYTNHRIKLILSNEDLGATNARNIGIKNSRGKYISFLDDDDE
                     YMPDRILKLMACFKKSRMKNLALVCSYGIIIYPNGTREEEKTDFVGNPLFVQMVHNIA
                     GTSFWLCKKEVLELINGFEKIDSHQDGVVLLKLLVQGYQIDIVREFLVNYYAHSKENG
                     ITGVTQKTINADEEYYNYCRKYFNLLSFNERILVTKKYYSLNIKRLLLIGDKCKALKV
                     IKKAREEKIFNEFLF"
     gene            14603..16219
                     /locus_tag="VU534_001342"
     CDS             14603..16219
                     /locus_tag="VU534_001342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU1513922.1"
                     /translation="MYTIIKSNIKKFSLLTIFIVAGQLLLIYAATINALVLNELIAMN
                     LERFLKLSIYQMIVWCGIIFLDWVVKNYQVEVIQEFNLEIRNRVATDISNSTYQEFHS
                     KSSGTYLSWLNNDVQTLNDQAFKQLFLVIKGISGTIFAVVTLNHYHWSLTVATLFSLM
                     IMLLVPKIFASKMREVSLNLTNQNEAFLKSSETILNGFDVLASLNLLYVLPKKIKEAG
                     ILLKMVIQRKTTVETLAGAISFFLNIFFQISLVFLTGYLAIKGIVKIGTIEAIGALTG
                     VIFTALGELGGQLSSIIGTKPIFLKLYSINPIESNKMNDIEPNEVNRDFPLYEAKNIC
                     YKYGDKEILKNLNFCFQRNEKYLILGESGSGKSTLLKLLNGFLRDYSGELRFCGDDIK
                     KTSYLNMVSNVLYVDQKAYLFEGTIRDNILLEENYTDEEILQSLEQVGLSVKDFPNNI
                     LDYYVGDDGRLLSGGQKQKITLARGLIRNKKIVLIDEGTSAIDRRTSLAIERKILDRE
                     DLTVIIVTHAPHPELKQYFTKIYQFPKDFI"
     gene            16480..16908
                     /locus_tag="VU534_001343"
     CDS             16480..16908
                     /locus_tag="VU534_001343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001290269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1513923.1"
                     /translation="MSEIVEMSKKISDLNDKKEFHKKNCELRFQDSVLDNINSVPGTT
                     HLFSCLNIQTLVKIILYIFRYNSCMKIFNFRDKELIFFNKIVNGLIQNIEENLEDDIE
                     RILKYLYICLFNEIFIIKNKVNFFDDVEFNQTLSEFLDKL"
     gene            16920..17669
                     /locus_tag="VU534_001344"
     CDS             16920..17669
                     /locus_tag="VU534_001344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000069862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIG-L family deacetylase"
                     /protein_id="HEU1513924.1"
                     /translation="MSNNTKYIFLSPHLDDAIFSCGDYISKLTSEGEIVLVITIFSGY
                     PLSQQLQPSAKQFHKLCNLGKYPIEERKKEDRLACERLQCDFRHLSYYECLYRKDRNG
                     NFLYRHIYSELKNEDTLKNDIIKELLMHLDDKCVVYCPLSLGDHVAHVFVNSIGRALE
                     FMRYKVIYYEDFPYVSDSSMVSYMGKTKELKMYQEELDEKNYIDRISSILCYKSQILI
                     IWKSVEKLLNNIKELYLRNGAAYSIRFWIKK"
     gene            17682..18853
                     /locus_tag="VU534_001345"
                     /pseudo
     CDS             17682..18853
                     /locus_tag="VU534_001345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017606.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide sugar dehydrogenase"
     gene            19249..20112
                     /locus_tag="VU534_001346"
     CDS             19249..20112
                     /locus_tag="VU534_001346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE/MutR family transcriptional regulator"
                     /protein_id="HEU1513925.1"
                     /translation="MIERMELGEFYKELRLARKLKQSDVACEGLTASQLSKFELGQSM
                     LSADKLILAIQGINVTFDEFGHKLNNYQESPHMRIGRKVVNRFAHQDIAALEQLLEEV
                     DQEQMAQTYRRLNAIVIKDAIHSLNKSYPLAEEDSEFLTTYLYAIESWTWFELYLFCN
                     TMPFLSNQDLIFLSTSLLEKSKEFKELVHNRLYMKQGLLNILSELMERKLFSYIPIFE
                     AELERMLRPYDVFEKVSWQFLKKMSVFLQTKGSNQKEIERFIQSLQVLENPQLIALFE
                     LRFQQYKELID"
     gene            20398..20631
                     /locus_tag="VU534_001347"
     CDS             20398..20631
                     /locus_tag="VU534_001347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000933479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1513926.1"
                     /translation="MLNLQFAETMELTEAELQDVRGGNLVNSMGGGGRSGISGWGVPG
                     IYPGWGNQGMSPNRGAFDWTIDLADGLFGRRRR"
     gene            20653..21330
                     /locus_tag="VU534_001348"
     CDS             20653..21330
                     /locus_tag="VU534_001348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU1513927.1"
                     /translation="MKKMKEVKFHLATGLLILTYYLIFNVTSDLDFMVALSDNMYYVF
                     QVLLVLILGTIATIAFVKSEHWKECGRFQFRWSYLGVFLLSFFLLFVWANLTTYIFPR
                     TQNGSTVVEVATNLTGISYFVTRILYTSIIAPVSEEVVCRGLLMTSLSKVKRYYLDVL
                     VSAAIFGAMHVLQYGWITTDFIKYFGMGLIFCMMFRYTRSIYWAIALHASWNSFLLIV
                     TLLVFGY"
     gene            21342..22007
                     /locus_tag="VU534_001349"
     CDS             21342..22007
                     /locus_tag="VU534_001349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000720786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU1513928.1"
                     /translation="MKKIISHRYFIIVFLLVIADQKFSVLVLRSDLVTGLSDFAYYLS
                     DMMLNFLVVLFALIAMIWSGKWQKINSRKFKGSYLFYSFLALLAFVVWNFVTFFLFPP
                     TRNEISYQHAAPTFTGATAFLMYFFYPVIAGPIFEDMIYRGLVMTALEKGKKWGLDVL
                     GSAVLFGVSHISNHGWVLTDFVFYMGGGLIFAVLFRMTKSIYWPIGLHIVYNGIGQLL
                     MLL"
     gene            22079..23305
                     /locus_tag="VU534_001350"
     CDS             22079..23305
                     /locus_tag="VU534_001350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEU1513929.1"
                     /translation="MKVFLQNRDFRQLTINQWISTLGDTIFYLAFLNYVADASFAPLA
                     ILLITISETLPQVLQIFLGVLADFQHHRVLKYTVISFAKFLLYSIVSLSLSGQSFSLL
                     LVAFICLINLLSDTLSYFSGAMLTPIFIRIIGQDHLAAAIGFKQSTVSLVKTISNILG
                     GVLLGILSIQFISLLNALTFLIAFLGILFIKTDLLKVEKTISYQEGLSVKSFCQHLLQ
                     SSKLIWNMNKVLLVLFIISTSQAVINVTVPISTLFLRNQPFLNLQTGQSLALLATLEL
                     SALIVGSLVSGYLQHTISIKTALYASLVIQLLLLVGFATVRFDWILIFSTLDAFFAGV
                     LSPRLQELVFKQIPEESMGAVQSSIGAITVVLPSLFTIALVTIATSFGTLAVSFVLLL
                     FLLVAFVMLLNIRESI"
BASE COUNT         7109 a         3972 c         4977 g         7344 t
ORIGIN      
        1 aggtgccctt gcagtcaaca caactgtaga tggctataaa gtcaatgcca atggtgaatg
       61 ggtttaagcc gattaaatta aatcatgtta agaacatttg acattttaat tttgaaacaa
      121 agataaggtt cgattgaata gatttatgtt cgtattcttt aggtacctat cttatgattt
      181 caggaaatgt cattaaaaaa acgactcatt ttctctaact tgaaaaatag attagagaaa
      241 atgggttgtt ttatttatta tagttatttg aatgaagata agaagaaggt atactcacat
      301 cattcacata atctgtatat tgactataag ttttaaaaaa caatttttaa gctcttcctt
      361 gtcttctcta accaagcgtg ttataatgaa tactgctcaa gcgaccttca atcgtgaagc
      421 acacacgacc ttcaatcgtg aataaacgaa tagatgggag acttaccatg agtgataact
      481 ctaaaacacg tgttgtcgtg gggatgagtg gtggtgttga ttcgtcggtg acggctcttt
      541 tgctcaagga gcagggctac gatgtgatcg gtatcttcat gaagaactgg gatgacacag
      601 atgaaaacgg cgtctgtacg gcgaccgaag attacaagga tgtggttgcg gtggcagacc
      661 agattggcat tccctactac tctgtcaatt ttgaaaaaga gtactgggac cgcgtttttg
      721 agtatttcct agcggaatac cgtgcagggc gcacgccaaa tccggacgtt atgtgcaaca
      781 aggaaatcaa gttcaaggcc tttttggact atgccataac cttgggggca gactatgtag
      841 cgactgggca ttatgctcga gtggcgcgtg atgaggatgg taccgttcac atgcttcgtg
      901 gcgtggacaa tggcaaggat cagacctatt tcctcagcca actttcgcaa gaacaacttc
      961 aaaaaaccat gttcccacta ggacatttgg aaaagcctga agtacgcaga ctagcagaag
     1021 aagcaggcct ttcgactgct aagaagaaag actcgacagg gatttgcttt atcggagaaa
     1081 agaactttaa aaactttctc agcaactacc tgccagctca gcctggtcgc atgatgactg
     1141 tggatggtcg cgatatgggc gagcatgcag gtcttatgta ctatacaatc ggtcagcgtg
     1201 gcggactcgg tatcggtggg caacacggcg gtgacaatgc cccttggttc gttgtcggaa
     1261 aagatctaag caagaatatt ctctatgtag gacaaggatt ctaccatgat tcgctcatgt
     1321 caactagcct agaagccagt caagtccact ttactcgtga aatgccagaa gagtttacgc
     1381 tagaatgtac ggctaaattc cgttaccgtc agcctgactc taaggtgacc gttcatgtca
     1441 aaggagaaaa gacagaggtc atctttgcgg aaccacaacg cgcgattaca ccaggacagg
     1501 cagttgtctt ttacgatggc gaagagtgtc taggtggcgg tttgattgac aatgcttacc
     1561 gcgatggaca agtttgtcag tacatttaga ttgacaaatt ttctcaattt gctacaataa
     1621 taacagcaat agaaatgatg gtcaaagctc atggatgttg caggcttttt tgtcctgcac
     1681 ttctttgtag ttttgactgt ttttgtgtcg tttaagggaa aggacaagaa tgactcaaca
     1741 agactttcgg acaaaagtag acaatacggt ttttggtgtt cgggctacag ccttgattgt
     1801 ccaaaatcac aagcttctag ttaccaaaga caagggcaag tattacacta ttggaggtgc
     1861 gattcaagtc aatgaaagca cggaagacgc ggtagtccgt gaagtgaagg aagaactggg
     1921 tgtcaaagct caagctgggc agctagcttt tgtggttgaa aatcgttttg aagtggacgg
     1981 cgtttcctat cacaatatcg agtttcatta tctggtggat ttgcttgaag atgccccgtt
     2041 gaccatgcag gaagatgaga aaaggcagcc ctgtgagtgg attgacttgg ataagctcca
     2101 gaatatccag ctagttccag tctttttaaa aacagcccta ccagattggg aaggccaact
     2161 aagacacatt catcttgagg aataggagag aaacatgact tatcatttta ctgaagaata
     2221 cgatattatt gtaattggtg cgggacacgc tggggttgag gcttccttgg ccgctagccg
     2281 tatgggctgt aaggtcctgc ttgcgaccat caatattgaa atgctggctt tcatgccttg
     2341 taatccctct atcggtggtt ctgccaaggg gattgtcgtg cgtgaagtcg atgccctcgg
     2401 tggcgagatg gccaaaacca ttgacaagac ttacatccag atgaagatgc taaacacagg
     2461 gaaggggcca gctgtccgtg cccttcgtgc gcaggctgac aaggaacttt actctaagga
     2521 gatgcgcaag acggttgaaa accaagaaaa tctgaccctt cgtcaaacca tgattgatga
     2581 gattttggtg gaagatggca aggttgtcgg tgtgcgtaca gccacccatc aagaatatgc
     2641 tgctaaggct gttattgtga cgacagggac tgctctccgt ggggaaatta tcatcggaga
     2701 cctcaagtac tcatcaggtc ctaaccacag cttggcttct attaacctag ctgacaatct
     2761 caaggaactg ggtctcgaaa tcggtcgttt caagacagga acccctccac gtgtcaaggc
     2821 ttcttctatc aattacgatg tgacagaaat tcagccagga gacgaagtgc ctaatcattt
     2881 ctcatacact tcacgtgatg aggattatgt caaggaccaa gtaccatgct ggttgaccta
     2941 taccaatggt accagtcatg agattatcca aaacaacctc caccgtgcgc ctatgtttac
     3001 aggtgtggtc aagggagtgg ggcctcgtta ctgtccgtcg attgaagaca agattgtgcg
     3061 ctttgcggac aaggaacgtc accaactctt ccttgagcca gaagggcgca atactgagga
     3121 agtctatgtg caaggacttt caaccagtct gcctgaggat gtccagcgtg acttggtgca
     3181 ttccatcaaa ggtttggaaa atgcagagat gatgcggaca ggttatgcta ttgagtatga
     3241 tatggtcttg cctcatcagt tgcgtgcgac tttggaaacc aagaaaatct caggtctctt
     3301 cactgctggt cagacaaatg gaacatcagg ttacgaagag gcagcaggcc aagggattat
     3361 cgcgggtatc aatgcggctc tgaaaatcca aggcaagcct gaattgattt tgaagcgcag
     3421 tgatggttat atcggggtga tgatcgacga cttggtgacc aagggaacca ttgaacccta
     3481 ccgtctcttg accagtcgtg ctgaataccg tctcattctt cgtcatgaca atgctgatat
     3541 gcgcttgact gagatgggac gcgagattgg ccttgtggac gatgaacgct gggctcgttt
     3601 tgaaatcaag aaaaatcaat ttgataatga gatgaagcgc ctagacagta tcaaactcaa
     3661 gccagtcaag gaaaccaatg ccaaggttga ggagatgggc ttcaaaccct tgaccgatgc
     3721 agtgacagcc aaggaattcc ttcgccgtcc agaagtttct taccaagatg tggtggcctt
     3781 catcggacca gctgcagaag acttggatga caagattatc gaattgattg aaacagaaat
     3841 caagtatgaa ggctatattt ccaaagccat ggaccaggtt gccaagatga aacgcatgga
     3901 agaaaaacgc attccggcca atatcgactg ggatgacatt gattctatcg caaccgaagc
     3961 ccgtcagaag ttcaaactca tcaatccaga aaccatcggc caagccagcc gtatttcggg
     4021 agtaaaccca gcagatattt ctattttgat ggtgtatctg gaaggtaaaa atcgtagtat
     4081 ttctaaaact cttcaaaaat caaaatgata cgtcgtcggc ttcttacgaa tgagttcaaa
     4141 gcttggcttt gattcatctc cagcctccca tagtttcccg aactatggga gctaactcaa
     4201 gttatgcttt cgcttagcct tctagtctga tttcgatttt tattgatact cttcgaaaat
     4261 ctcttcaaac cgcgtcaacg tcgccttgcc gtaggtatgg ctactgactt cgtcagttct
     4321 atctacaacc tcaaagcagt gctttgagca acctacggct agcttcctag tttgctcttt
     4381 gattttcatt gagtatgagt tttaatctca aaagaaagca tagagaaaaa cagctccgag
     4441 gacggggctg ttttcttgct ttattcttca tctggtgtga ggatcatcgg gatgatgatc
     4501 ggttcacgtt cggtattttc atagaggaag gggcgaatag cgttgacaat ggcaccattg
     4561 acagattgca cgctagcatc cttatttttc agtgcgatac gaatggcatt gaagaggata
     4621 cgctggcttt ggcgaatcaa gtcgccagac tctctcatgt agacaaagcc tcggctgagg
     4681 atgtctggac cagatagaat catctgcgat ttgaagtcaa cagttgcaac tgccagaacg
     4741 acaccgtctt cagatagatc gcgacgatct ttgaggacag ctgcgccaat ttcaccgata
     4801 cgatttccat cgacatagat atcttgggcg ttgaaatgac ctgcgatacg agctgagtca
     4861 gcagtaaggg caagcacatc gccattgctc atgataaaga tattgtcctt ctcaacacca
     4921 gtatccactg ctagtccagc gtggactttt tgcatgcggt attcaccgtg gacaggcatg
     4981 aagtattttg gcttaatcaa gcagagcatg agtttttgct cttgctgacc accgtgtcca
     5041 gatgtatgga tattgttcac tttaccgtgg ataacttcga caccagcttc agaaatgatg
     5101 ttaatcagct tgttgacact agtagtgttt ccagggatgg gactagaaga gaagataacg
     5161 gtatcacctg gttgtaattg tacttgacgg tgggttccgt tggcgatacg agagagggct
     5221 gccataggct caccctgact acctgtacag aggataagaa cttctcctgc aggataatct
     5281 ttgatttcat ttggctcgat aaaggttccc ttaggagctt tgatgtagcc aagatcgatt
     5341 ccgttgacaa tggccttttc catagaacga ccaaagaccg caatcttgcg tccagtctta
     5401 acagcagctt ctgttgcctg ctggagacgg aagatatttg aggcaaagga tgcaaagatg
     5461 atacgtcctt caataccttg gataatcttc ataatggact gaccaacgac tttttcagag
     5521 ttggtaaagg ttggtacttc cgcatttgtc gagtcagaca ggagacagag cacgccttct
     5581 tcaccaagcg cagccatacg atgcaagtcc gcaggttctc caactggagt aaagtcgaac
     5641 ttaaagtcac ccgtacagac gattttccct tgaggagtat gaatgacaat ccccaaaggc
     5701 tctggaatag agtgagtcgt tctaaagaaa gttgccttga gatttttaaa ggtcaactcg
     5761 gtgttgtggt tgatttcgta aagtttggcg ttgcgcaaga ggccgtgttc ttcgagtttc
     5821 ccacggatca aagccaaggc aagcggtcca gcataaatag ggacatttgc ttgcttgagt
     5881 aggaacggaa tcccaccaat gtggtcctcg tgtccgtgtg tgattaaaac agccttgacg
     5941 cggtcgatat tgtccacgat gtaagagtag tcaggaatga catagtcgat accaagcaag
     6001 tcatcttctg ggaatttaat cccagcatcg acgatgataa tctcgtcttg gtattcaatt
     6061 ccgtaagtgt ttttcccgat ttctcctaga ccaccgatgg caaaaacgcc gacttcttca
     6121 ggtttaagag tgtaggccat attagaactc cgtaatttcg aaggcgccag tttctttttc
     6181 gtaatcgagc aatttgtcag acaagagttc gatatactcg atattgtact ctgggcgatt
     6241 ttcttcgaca agttggcgag cagtgatacg gccctcaagt tctgagctgg catcgatgtc
     6301 taggtaaagc gtgcgtgttg tttcacggcg tgggctacgt tcttttgttt cttgataaaa
     6361 aactttgtaa atcatatagt tcctttctat ttacaggtca gcttattcca aacttttagc
     6421 agatatttgc ttgatttcat tccattttgt gtctagattg accttgattc gttacaatta
     6481 tttcaattat accacaaaat gaaaaattag taaaagacgg aaacgagaaa gttaggggac
     6541 gatttctttg gtaagcgttt tcaaaaataa agaaaatgta ttatgttgat aacggaagtg
     6601 aaatttattg cttgtcataa ttccatatag attttaagtc aaggaggttg ccctatgtat
     6661 aacttatttg cttttgctat cggagctcgc ttggtagctt ttattgtttt tgttgcttgc
     6721 gtttatgcgg ggaatcttct atttgccaaa ctggaacgac gacaaaccaa gttcttgtgg
     6781 aaaatgacct ttgtgactct ctactcgctt tttctcctcc tcgtgaccta tgtcgtttgg
     6841 tttgtatttt actttgaatt aaatgcttag atgccctgct tatgctgggg ttttttgttt
     6901 gggaatgtag agatagtaga tttacgacac gaaaattcca ccccatctat caagatgagg
     6961 tggtctttgc atttttctaa catgacatga caatggaatt ttcaaagctt attattttta
     7021 tgggagtcat tgttctgatc aaaaatagag ttgaagcata aaaataaaac aatacaaaca
     7081 gataaatcga atggtaaagg gatggtagta atgttcaaat cattgagaat gctgagcaaa
     7141 ctgtaagaga tgaagacaat aaaatttatc cttctaaaaa tgtgtttctt atctagcatg
     7201 acttaccaaa ctttttacga aggtcttttc caatggtata acctgccata aataaagcga
     7261 taccaacacc gacaccaaag ccacccttga tttcttgcaa ttccttatta gaaatttcac
     7321 gataattgtt caaatctttc atcatattaa tctcctccta aaaaataacc agctgccaaa
     7381 ccagaaccta taagtgctgt tccacctgca atagccttcc aagatactgc tactccaaag
     7441 ataaccaagg gagcgagacc gccatcaata tctgataatt cattttcaga taaggataaa
     7501 aattgattgt caagaatgtc aaaatttgtc attgaacttt cctccttttt tcttgttcac
     7561 ttttatattc ggaaaagaaa aggaaaagtg agcatttttt taaattattt ttagttaagt
     7621 gagggcactc ttgtctgggg gcaaagaaaa ttcccatgtg ccagcttttg tagtataata
     7681 gtaagcagac aaaaagatag gaatgtgtta tgaaagtatt agcttttgat acgtccagca
     7741 aggctctttc tctggctatt ttagaggata agcaggttct tgccgagacg acgattaata
     7801 ttaagaaaaa tcacagtatt actcttatgc ctgccatcga ttttttgatg gcaagtttgg
     7861 attggacacc caaggatttg gaccgaatcg tggtagctga agggccgggt agctatacag
     7921 gcttgcgaat tgcggtagca actgctaaga ccttagctca caccctgaac atcgagttgg
     7981 ttggtatgtc gagtctcttg gctctggtgc cccatcaaca agaaggtttg tttgtcccct
     8041 tgatggatgc gcgtcgcaat aatgtttatg caggatttta tgaaaatgcc aaacctgtca
     8101 tggcagaagc gcacctatct tttgaagagg tgctagaaaa agtcaagggt actagtcagg
     8161 taacctttgt cggagaagtt ggcccctttg ttgagcagat tcaaaaacac ttgccaagga
     8221 ctgattacaa agaaacattg cccaatgcag ctaatctagc tcttttggcc tgggacaagg
     8281 aagcagactc cttgcatgat tttgtgccga attacctcaa acgagtcgag gctgaggaaa
     8341 actggctcaa gaaccatacc gagtctggcg agtcttacat taaacgccta tgatagaaat
     8401 caagcgaatt caacaacagc ctgacctagc tcaagccatc tacgctgtta tggcagctgt
     8461 ttacctagtc agtccttgga ctctggagca aatccaagca gatctgtccc aagaccagac
     8521 ttggtatgca ttggcttatg atggggcaga agtgattgga tttctagctg tgcaggagaa
     8581 tctttttgaa gcagaagtcc tgcaaatcgc tgtcaaagga gcttatcagg gtcaggggat
     8641 tgcgtcagcc ttgtttgctc aattgccgac agacaaggaa attttcctcg aagtcagaca
     8701 gtcaaatcaa cgagcgcaag cattttacaa gaaagaaaag atgacagtta tcgctgagcg
     8761 aaaggcctac taccatgacc cagtcgagga cgccattatc atgaagagag aaatagatga
     8821 aggatagata tattttagca tttgagacat cctgtgatga gaccagtgtc gccgtcttga
     8881 aaaacgacga tgagctcttg tccaatgtca ttgctagtca aattgagagt cacaaacgtt
     8941 ttggtggcgt agtgcccgaa gtagccagtc gtcaccatgt cgaggtcatt acagcctgta
     9001 tcgaggaggc attggcagaa gcagggatta ccgaagagga cgtgacagct gttgcggtta
     9061 cctacggacc aggcttggtc ggagccttgc tagttggttt gtcagctgcc aaggcctttg
     9121 cttgggctca cggacttcca ctgattcctg ttaatcacat ggctgggcac ctcatggcag
     9181 ctcagagtgt ggagcctttg gagtttccct tgctagccct cttggtcagc ggcggacaca
     9241 cagagttggt ttatgtttcg gaggcaggag attataagat tgttggggaa acccgtgatg
     9301 atgcggttgg tgaggcttat gataaggtcg gccgtgtcat gggcttgacc tatcctgcag
     9361 gtcgtgagat tgacgagctg gctcatcagg ggcaggatat ttatgatttc ccccgtgcca
     9421 tgattaagga agataatctg gagttctcct tctcaggttt gaaatctgcc tttatcaatc
     9481 ttcatcacaa tgccgagcaa aagggagaaa gcctgtctac agaagatttg tgtgcttcct
     9541 tccaagcagc agttatggac attctcatgg caaaaaccaa gaaggctttg gagaaatatc
     9601 ctgttaaaat cctagttgtg gcaggtggtg tggcagccaa taaaggtctc agagaacgcc
     9661 tagcagccga aatcacagat gtcaaggtta tcatcccccc tctgcgactc tgcggagaca
     9721 atgcaggtat gattgcctat gccagcgtca gcgagtggaa caaagaaaac ttcgcaggct
     9781 gggacctcaa tgccaaacca agtcttgcct ttgataccat ggaataaaga gtggctcttt
     9841 gtcaagtgta gtgggtaggc gaaaagctgc aatctggaga gtacgaaatt cgtactctct
     9901 tttttgatgt tcaaagtcat caaaatccgt tttttaaaat tgttaaagtt ccggaaacca
     9961 aaggctttgc gcttgataat cttaatcaaa ttattggtcg cttcaagttt agcgttggaa
    10021 taaggcagct taagtgcgtt gataatctta tctctatccc ttaaaaaagt ccaaaagacc
    10081 gtttgaaaaa gcggatgaac cgttggcagt tcttgctcaa tcaatccaaa gaaatggtcg
    10141 gcattcttct cttgaaaatg aaagagcagg agttgataga gttcgtagtg aacctgtaat
    10201 ccctcagagt aagaaagcag cttatctcgt acttcccgat gggttaagtg cattcgaaac
    10261 gtgggctgat agaatcgttt ctgacagagc ttgaagctat actggtgtag taaatcagtc
    10321 cagtggactg atttagcccg agcctagaaa cgaaaaagcg agggttccaa aagcgcttga
    10381 gcgcccgata ctccaaggat tttcggtcaa attggttcat gatttggatt cgtactcggt
    10441 tcatagctcg gctcagatgt tggacaatgt ggaagcggtc aagaacaatc ttcgcctttg
    10501 gaaagagttg cttagcgagc cgataataag ggctgtacat gtccatggtg atgacctcga
    10561 ccagctcccg aacctctctc tgatagcgtt ggaaatggtt tcgaatcacc gcatgagttc
    10621 gcccgtctaa aattgcgagg atggatttgg actcaaaatc ttgggcaatg aagctcattt
    10681 tgctcttttt gaagctatac tcatcccaac tcataacttt tggcaacttg gtccaatcgg
    10741 tttcaaactt aaattccctc agttttcgga tgacggtgga agttgagacc gccaatctgt
    10801 gggcaatctc agtcatagac tgcttttcaa ggaggagctg agcgattttt tgtctcacca
    10861 tgttggaaat ctggcaattt ttcttgacaa tggatgtttg agaaacgacc accttaaggc
    10921 aattcttgca ctgaaagcgg cgctttttga gatgcagtac cgtgggtaaa ccctgacagt
    10981 cgagaagcgg aattttagag gctttctgga agtcgtattt gatcatcttc ccttgacaat
    11041 gaggacaagg aggagcgggg gaatccaact ttgcctgaac gactagatgg gtttggtatt
    11101 tcagaacaga caagattttg atatttttgt cttccaatcc gagcaaatct gtggtattct
    11161 taagttgttc catatgaacc ctttctaatg agttggttag acgcttttca ttataggtca
    11221 tatggggctt tttttctaca agaaacgacc ctataattcc tggggtggga ttacccacta
    11281 cagaaattat agagccaaaa cattccaaag tcttgtctga ctctggaatg ttttctgttc
    11341 acagttgttt tgtaactgcc taataagtaa ccgcgctata acgaggtatc taccgagatt
    11401 gtcaattctc cagtatactg ttataaaaaa caaaactgga ggattttttt atgtcccccc
    11461 atcgtcccat cgactgttcc gtagctgccc aataacggag tatagtcggc tgaaacaaga
    11521 ataggacaaa agtgcctcaa gaaaagcatc gtaatttgac aatattattc tgagatgttt
    11581 ttgatgtaag cccatatttt ctcaatggga ttatactcgg gtgaataggt aggaagtggt
    11641 aacagtctat gccctgctcc ttacacatgt tcattctgtg aaaccttgca ttgtccataa
    11701 tgataaggga tggtgtatct aaagtaggta gtaagaattt ttggaagcaa gcttcgaaaa
    11761 agtcactcgt catcgtatct ttataggtca tcggagccat agtatattga aacaaaaaag
    11821 ggcattagta cttctataac agtatcgcaa tctctggtgt gcgttgtctc gatcttaatt
    11881 caaataatta tatcttcttc cagagagact aactgcctgc tcaaggctcg atcatattcg
    11941 agataaaaat aggtctcaac ccctgtctca taaatataaa taggagtcag gtagcttaag
    12001 tgattcaatt ctttaaggaa ccgatttact ttttctgggt cttgttcgca gtaggtacgg
    12061 ctctttttta gactatatcc catagccttt agagcgtaat gaatagttgt tggaggacag
    12121 ttgaattcag cagctatttc agtcaaataa gcatcgggat gagtttcaat atagattttt
    12181 aatttatctc tatcaatttt ttcaattaat agtggaagtt ttcttgaagt tagtgtattg
    12241 aaacgttttt atacagtgct aaaatttgaa gtgtagtgca gatggatttg taatagtatt
    12301 atagcaattc tttggagaag gtcgagacaa gataaaatag gtatctttga gatataagca
    12361 tgatttacta taaaattatt gagttattca taaaaatttc tctatcaaat atcataatgc
    12421 gtcgtttaag gagatggtta caatgcaata tagttgtgga aaaataaata ttaatatccc
    12481 tgatggatat ggagacatta aggatatagt gttttcggct catattatag ttaggtataa
    12541 taatggacat tgtggaggta tagatccgca tataattgga ctttgtaaaa agcagatcag
    12601 aaggatgtct ctatatccta ttttgataat tgtatctaga gattcaaagg ttattgatga
    12661 ttataaaaat ttagatattg cctatgttga ttgtactcaa tgttcaaata attttgaaac
    12721 tgccttacac gttaaaaata ttttaaaatt attaaaaatc caacttatac actgtcatgg
    12781 ctactcaact aattattttt tatatatgtt aaaaaaactt gacaagaatg gatttggaaa
    12841 ggttaagaca gtgataacat gccatggatg ggttgaatat aacttaaaaa agaaattctt
    12901 gacttatttt gatttttgga catattctat gggagatgct tttatttgtg tatctgaaac
    12961 tatgaaaaaa aagattggag agtataataa aaaataagaa gatagttgca ataaataacg
    13021 gaattaatgt atcaaatagc gatttagatg tagtaggtgt tcaagacttt aaaaaagaat
    13081 tttgtattcc aaataacaaa aaatcatttg ttatgttgga aggttggatc cagaaaaaag
    13141 gccggataga ttccttgaat ttgcagaaaa attattttta gtcagagaag atgtgatttt
    13201 tattatggct ggaaatggta gtatgtgggc tgctttgaaa gaaaaaattt gccatttgaa
    13261 atgtagagat aatttcaggt tacttggtga aatctatcca gctactatag tttaccaaat
    13321 atcggattta ttgtatattc cttctgatac agaaggaata cctatgtgtg ttttagagtc
    13381 aatgtcacaa ggaactccgg ttttagctag taatgttggc gggttaagtg aaattattga
    13441 acatagggtt gatggatttt tatttgagaa ggaagatgtt gagggagtgt gtgcttgtgc
    13501 taatttttta ctcaatgatt ctgagtattt gaaatatata ggtgagaata gtaaatcaaa
    13561 aataagaaaa catttttctg tgcaaaaaat gtttgtagaa accatgagag tatatgatga
    13621 attattagag aagagtagtc atggatagga atatagatca agaattagta agtattataa
    13681 taccaacaca taataggtat gaatctctga ttagagctgt gaaaagttgt ttacatcaaa
    13741 gttataaaaa tatcgaagtt ataattattg atgataatta tagtaatgta aatttaagaa
    13801 ataaaattat ccatcaattt ggctatacca atcatagaat taagttaatt ttaagtaatg
    13861 aagatttagg tgcaactaat gccagaaaca taggtatcaa aaattctaga ggtaagtata
    13921 tatcattttt agacgatgat gatgaatata tgccagatcg aattttaaag ttgatggctt
    13981 gttttaaaaa gagtagaatg aagaatttag ctttagtttg tagttatgga ataataattt
    14041 atccaaatgg tacacgagaa gaggagaaga ccgattttgt tggaaatccc ttgtttgttc
    14101 aaatggttca caatatagca ggtacgtcat tttggttgtg taaaaaagag gtgctagaat
    14161 taattaatgg ttttgagaaa atagattcac atcaggacgg tgttgtttta ttaaaactac
    14221 ttgttcaagg ataccaaatt gatatagtgc gagaattctt ggtgaattac tacgctcaca
    14281 gtaaagaaaa cggtatcact ggagtgacac aaaaaacaat taatgcagat gaagaatatt
    14341 ataattactg taggaaatat tttaatttat tgagtttcaa cgagagaata ttggttacaa
    14401 agaaatatta ttctttaaac ataaagcggt tactattaat aggagacaaa tgcaaggctt
    14461 taaaagtaat caagaaggca agagaagaaa aaatttttaa cgaatttctt ttttgaaata
    14521 tatgttatta tatcattttg gttttttcta ttgtatatat gaaaactatg ttcaattaaa
    14581 atttagaaag tgagaaacta ttgtgtatac tattataaaa tcaaatataa aaaaatttag
    14641 tttattaacg atatttattg ttgctggtca attattgcta atttatgcag caactattaa
    14701 tgctctggtg ttgaatgaat taattgcgat gaatttagag cggtttttga aattgtcaat
    14761 ctaccaaatg attgtctggt gtgggataat attccttgac tgggtagtga aaaattatca
    14821 ggttgaagtg atccaagagt ttaatctaga gattcgaaat agagttgcca cagacatctc
    14881 taactctacc tatcaagaat ttcatagtaa atcatcagga acatatcttt cgtggctaaa
    14941 taatgatgtt cagactttaa atgatcaggc gtttaaacaa ctttttttag taataaaagg
    15001 aatttctggt actatatttg cagttgtgac tcttaatcac tatcattggt cattgactgt
    15061 agccaccttg ttttcattaa tgattatgct acttgtacca aaaatctttg catcgaaaat
    15121 gcgagaagtt agtctaaatt taactaacca aaatgaagct tttttaaaat ctagtgagac
    15181 tatattgaat ggatttgatg tgttagcgtc cttgaatctt ttatatgtat tgcctaagaa
    15241 aattaaagaa gcaggaattt tattaaagat ggttatacaa agaaagacaa ctgtagaaac
    15301 gttagcaggc gctattagct tctttctcaa tatttttttt cagatatctc tcgttttttt
    15361 aacaggctat cttgcaataa aaggaatagt gaaaattggt actattgaag caataggagc
    15421 actaacaggt gttattttta cagcgctagg tgaattagga ggtcaattat cctctattat
    15481 tggtacgaag cctatttttt taaaattgta ttcaattaat ccaattgagt caaataaaat
    15541 gaatgatatc gaaccaaatg aggtgaatag agattttccg ttatatgaag caaaaaatat
    15601 ttgctataag tatggagata aagaaatatt aaaaaactta aatttttgtt ttcaacgtaa
    15661 tgaaaagtat ttaattttag gtgaaagtgg aagcgggaaa tctacattat taaaattatt
    15721 gaatggcttt ttgagagatt atagtggaga attgcgattc tgcggggatg atataaaaaa
    15781 aacctcctat ttaaatatgg tttcgaatgt tctatatgta gatcaaaaag cttatttgtt
    15841 tgaaggtacg attagagata atattttatt ggaagaaaat tatactgatg aagaaatact
    15901 acagtcttta gagcaagttg gtttgagtgt aaaagatttt cctaataaca ttttagatta
    15961 ttatgttggt gatgatggga gattactgtc aggagggcag aaacaaaaaa ttactttagc
    16021 tagagggcta attagaaata agaaaatagt attaattgac gagggaactt ctgctatcga
    16081 taggagaact tcgttagcga ttgaacgtaa gatattagat agagaggatt tgactgtcat
    16141 tattgttacc catgctccgc atccggaact taaacaatat tttactaaga tatatcaatt
    16201 tccaaaggat tttatttaag aatatagggg agggaaacat gagattctat tgtgaagctt
    16261 atgaggtaat tactgaagag aaaaaagtat cattttttta tgtagatgag aaacccttaa
    16321 ggtatctgtt atttgactat atatttctac tagttctagc taaaaaaaaa tatcccaatc
    16381 ttatgaactg caccccaaaa gttagattta ttctgtctaa cttttggggt gcagttcatt
    16441 ttgcatagtt ttggcattca tcctagatat ccatataaaa tgtctgagat tgttgaaatg
    16501 tctaaaaaaa tatcagatct aaacgataaa aaagaatttc acaaaaagaa ctgtgagttg
    16561 aggtttcaag atagtgttct tgataacata aatagtgtcc cgggtacaac tcatttattt
    16621 agttgtttaa atattcaaac attagtaaaa attattttat atatttttcg atacaacagt
    16681 tgtatgaaaa tatttaattt tagagataaa gagcttatct tttttaataa gattgtaaat
    16741 gggctgatac aaaatattga ggagaattta gaggatgata ttgaaaggat attgaaatat
    16801 ttatatatat gtttatttaa cgaaatattc attattaaga ataaggtgaa tttttttgat
    16861 gatgtggaat ttaatcagac acttagtgag tttttagata aattgtagag ggaatggtta
    16921 tgagtaacaa tactaagtat atctttttat ctccacattt agatgacgca attttttcct
    16981 gtggtgatta tatttcaaaa ttaacttcag aaggagaaat tgtacttgtt attactatat
    17041 tttctggtta ccctttgagc caacagctac agccctctgc taagcaattt cataagttgt
    17101 gtaaccttgg gaaatatccg attgaagaaa ggaagaaaga agacaggtta gcttgtgaac
    17161 gtctacaatg tgattttaga cacttatcgt actatgaatg tctctatagg aaagatagaa
    17221 atggcaattt tctataccgt catatctata gtgaattaaa aaatgaggac acattaaaga
    17281 atgatatcat aaaagagctg ttaatgcatt tagacgacaa atgtgtcgta tattgtccgc
    17341 tttcacttgg tgaccatgtt gctcatgttt ttgtgaatag tattggaagg gcgcttgaat
    17401 ttatgcgtta taaagtaata tattatgagg acttcccata tgtaagtgat agtagtatgg
    17461 ttagttatat gggaaaaact aaagaattaa aaatgtatca agaggaactt gatgaaaaaa
    17521 attatattga tagaatatca tcaatattgt gctataaatc tcagattttg ataatctgga
    17581 aatcagttga aaaactttta aacaatatta aagagttgta tttaaggaat ggggcagctt
    17641 attctattag attttggatt aagaaataag gaagtagttt tatgaatata gcagtaattg
    17701 gtttggggca tgttgggctg gcctacgcgt tactatttgc atctaaatat aaagttgttg
    17761 catatgatat agattctgta aaaataaata atttaaaaaa gggcattctt ccatctaaaa
    17821 atgaagagct tatgaagttt ttttgcgaga ataacttaaa tattactttt tttgatacat
    17881 tttctgaaat taaaaataat attgattatt atattattgc gcttccgaca gattatgatg
    17941 agaaaattgg tagttttaat acatatgaaa tcgaacaaac ggtatcgaag attctgaggg
    18001 taaaacctaa tggaaagatt attttaaagt caacagttcc gatcggcttt tcaaacaaat
    18061 taaaaaggct gtttgataca aaaaatatca tttttgtccc tgaatttttg agagaaggtt
    18121 gttctatata tgataattta tatccaagtc gcatagttgt tggagatgag acagttgaag
    18181 gaagaaaaat tgcagagttg ttcctttcga ttagtactca tagtactgcc aatattaaaa
    18241 atgttatgtt agtttctcct actgaagcag aagcaattaa gcttttttct aacacattct
    18301 tagctctccg tgttgctttt ttaatgaact agattctttt gctgagagga gaagcttaaa
    18361 tgctgaagtt gtaataaaag gtgtttgttt agatccaaga attggaaatt tttataataa
    18421 tccttctttt ggatttggag gatattgtct tcccaaagat actaaacaat taaaaaaaga
    18481 atttatagaa ataaatgccc cagtgataga agcgattgat atttcaaaca caaatagaaa
    18541 acagttcata gttaaacaaa tattggaacg aaagccaaag atagtaggaa tatataaatt
    18601 ggggatgaaa tataattcag ataattacaa agagtcagct attttaagta taattaatga
    18661 actattgatt gtcggtataa aaattttagt atatgaacca aatttaaacg ttagtataga
    18721 taacgtaatt attgaaaaga attttgaact atttacaaaa caaagtgatc taattgttgc
    18781 aaatagatgg gataggggcc ttgaagctta taaagataaa gtttacacaa gggggatctg
    18841 gataagagat taactattga tattaaaaag gcaataattt ataaaatttg tacaaaaaaa
    18901 tgttaaattt tcacattttc atagtatact gtttaataga aagtaggttc tttgtaaccg
    18961 ctccattata aaatcctttc actcttccgg tatactatta ggaaaaacat aactggagga
    19021 tattttgagc tcacacctca tcgttccagt ggctgttccc caagctcgtg tactgcccaa
    19081 aaaagttaga cattctattt agaacgagga ttgagttctg tattgtacaa ggctcggtcc
    19141 ttttagagtc agcttaaggc tggctttttt attttttcta actatcagaa tattttgaca
    19201 aatgattgta aataatgata taatatgcaa aagctaggag gtggtcagat gattgagaga
    19261 atggaactgg gggaatttta caaggaatta cgtttggcga gaaagctcaa gcagtcagat
    19321 gtggcttgtg agggtctaac agcttctcag ttgtccaagt ttgaactagg gcagtctatg
    19381 ctgtctgcgg ataagttgat tctagctatc caaggtataa atgtgacctt tgatgagttt
    19441 gggcacaagc tcaacaacta tcaagaatct ccacatatgc gaatcggtcg aaaggttgtg
    19501 aatcgctttg cccatcagga tatagctgct ttagagcagc tattggagga agtcgatcaa
    19561 gaacagatgg cgcagaccta tcgtcgtttg aatgccatcg tgattaaaga tgccatccat
    19621 tcactaaata aaagctaccc actagcagag gaggatagcg agtttttgac cacctatctc
    19681 tatgctatcg agtcttggac ctggtttgaa ctctatctct tttgcaatac catgcccttc
    19741 ttgagcaatc aagatctgat ttttttatca acctccttac tcgaaaaatc caaagaattt
    19801 aaagagttag tacacaatcg attgtatatg aagcaaggac tcttaaatat cttatcagaa
    19861 ctcatggagc gaaaactttt ctcctacatc ccaatcttcg aagccgagtt ggagaggatg
    19921 ttacgaccgt atgatgtttt tgaaaaagta tcgtggcaat ttttaaagaa gatgagtgtc
    19981 tttcttcaaa caaagggaag caatcaaaaa gagattgaac gctttatcca atctctgcag
    20041 gtattagaaa atccacaatt aatagccctt tttgaattgc gttttcagca atataaagaa
    20101 cttatagatt agttagaaat ggcaaaataa taataatctc agcaacgatt ttcaataatg
    20161 ttaaaatttg tttcttcata tttctccact cctcattagt agtaacttta ttataccaga
    20221 gaagtaatca aattcaccaa aatcgcaaat ctgaaatttc tataagaaaa aatatcaaat
    20281 atgcgatttt ctaaaataag ccaatgttcg tgttatactg tacttgtaaa gcacttgaag
    20341 caaatcctag gtcgcagaag tggtttacaa atgaagataa ttgaaggagt gtaaaagatg
    20401 ttaaatttac aatttgcaga aacaatggaa ttgacagaag ctgagttgca agatgttaga
    20461 ggaggcaacc tcgtaaattc tatgggaggt ggtggaagaa gtggtatatc tggttggggc
    20521 gtcccaggaa tttaccctgg ttggggcaat caagggatga gtcctaatcg tggagctttt
    20581 gattggacta tagatttagc agatggattg tttggccgcc gtagaagata ggctcttata
    20641 ggagataata ggatgaagaa aatgaaagaa gtgaaatttc acctagcaac tggcttgttg
    20701 attttgactt attacctcat ttttaatgtc acatcagact tagattttat ggttgctttg
    20761 tctgataata tgtactatgt gttccaagtt ttattggtac ttattctggg aactatagct
    20821 acaattgctt ttgtcaaaag tgaacattgg aaagagtgtg gtcgtttcca gtttcgttgg
    20881 tcttacctgg gtgttttcct tctttctttt ttcttattgt tcgtgtgggc aaatctaaca
    20941 acctatatct ttcctcgtac ccagaatgga agtacagtcg tagaagtagc caccaattta
    21001 acaggaatta gctattttgt tacgcgaata ctttatacta gtattatcgc acctgtatca
    21061 gaagaggttg tttgtcgtgg tcttttgatg acaagtttat ctaaagttaa gagatactat
    21121 cttgatgttc ttgtttccgc tgccatattt ggcgctatgc atgttttgca gtatggttgg
    21181 ataacgacag atttcataaa gtattttgga atgggcttga tattttgtat gatgtttcgc
    21241 tacacccgat ccatctattg ggctatagct ctgcatgctt catggaatag tttcttactc
    21301 attgttactt tattggtatt tggatattag aaaggtgata tatgaaaaag ataatctcac
    21361 accgctactt tattatagtt tttctactag ttattgctga ccagaagttc agtgttctag
    21421 ttttacgcag cgaccttgtt actgggctat ctgactttgc ctattatctg tcggatatga
    21481 tgttgaattt tcttgtggtt ttatttgctc ttattgctat gatttggtcg gggaaatggc
    21541 agaaaatcaa tagtagaaag tttaaaggat cctatctttt ctattccttc ctagctctgc
    21601 ttgcttttgt tgtttggaat ttcgttacct tttttctttt cccacctact cgaaatgaaa
    21661 tttcttatca acatgctgct ccgactttta caggggctac agcatttttg atgtattttt
    21721 tttatcctgt gattgcaggt cccatttttg aagacatgat ttatcgtgga ttagtgatga
    21781 ctgctctgga aaaaggaaag aaatgggggc tagatgtact tggttccgct gttttatttg
    21841 gggtctcgca cattagtaat cacggttggg tcttgacaga ctttgtcttc tatatgggtg
    21901 gaggtcttat atttgcagtc ttatttagaa tgacaaagtc aatttattgg cctattggac
    21961 tgcatatagt ctacaatggc attggtcagc ttttgatgtt actgtaattt tggttgttag
    22021 tagtatcgcg gtctatcctt ggggaaagat tcccatttga acttaagaag gagttgtgat
    22081 gaaagtattt cttcaaaata gagattttag gcaattaact atcaaccagt ggatttcaac
    22141 gcttggggat acgatttttt atctggcctt cctgaattat gtggcagatg catcttttgc
    22201 ccctttggcg attttactca tcacgatttc agaaaccctg ccccaagttc tacaaatctt
    22261 tctgggagtt ttggcggatt ttcaacatca tcgtgtcttg aaatacacag tcattagttt
    22321 tgcaaaattt ttgctttact ctatagtgtc tttatcactt tcagggcagt ctttctcctt
    22381 gttgctagta gcatttattt gtctgattaa cctcttgtct gacacattga gttatttttc
    22441 aggcgccatg ctcactccga ttttcattag aattattggg caagaccatc tggcagcagc
    22501 tattggcttt aaacagtcaa ctgttagttt agtgaaaaca atcagtaata tcctaggagg
    22561 agtcttacta ggcattctat ccatccagtt tatttcctta ctgaacgctc ttaccttttt
    22621 aatcgcattt ttaggtatcc tcttcataaa aactgacctc ttgaaagtag aaaaaacgat
    22681 tagctatcaa gaaggactct ctgtaaaatc cttttgccag catttgctcc aatcatcgaa
    22741 attgatatgg aatatgaata aggtgctctt ggttttgttt attatctcta ctagtcaagc
    22801 agtgataaat gttacggttc ctatttccac tctattttta aggaaccagc cctttttgaa
    22861 tttacaaact ggtcaatctc ttgccttgtt agccacacta gaattatcag ccctgattgt
    22921 cggaagcctt gtaagtggct atctgcaaca taccatttcc ataaaaacag ctctctatgc
    22981 ctcacttgtc atccagttgc ttcttctagt aggatttgcc acagttcgtt ttgactggat
    23041 tctcatcttt agtaccttgg atgccttttt cgcaggtgtt ctctctccta gattgcaaga
    23101 actcgttttt aaacaaatac ctgaggagtc aatgggagca gttcaatcct ctatcggtgc
    23161 cattacggtt gttttaccta gcttatttac aatagctttg gtaaccattg ctactagctt
    23221 tggaactctg gcagttagct ttgttttatt gctatttctt ctagttgcct ttgttatgct
    23281 tctgaatatt cgtgaaagta tttagtggag aatttctata atatatgttt gagactggat
    23341 tgccagtctt tttatgatgg tcaaaatcaa cagacttttt tctcttttct gaatgtgtta
    23401 ta
//
LOCUS       DAVFER010000031        23310 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1105170250
            SAMEA2167659-rid19724873.denovo.031, whole genome shotgun sequence.
ACCESSION   DAVFER010000031 DAVFER010000000
VERSION     DAVFER010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2167659
            Sequence Read Archive: ERR388902
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 23310)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23310)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928716.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928716.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 04:07:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,118
            CDSs (total)                      :: 2,073
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 120
            CDSs (without protein)            :: 120
            Pseudo Genes (ambiguous residues) :: 0 of 120
            Pseudo Genes (frameshifted)       :: 67 of 120
            Pseudo Genes (incomplete)         :: 47 of 120
            Pseudo Genes (internal stop)      :: 34 of 120
            Pseudo Genes (multiple problems)  :: 23 of 120
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23310
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2167659-rid19724873.denovo.031"
                     /strain="1105170250"
                     /db_xref="taxon:1313"
     gene            complement(<1..217)
                     /locus_tag="VU534_001351"
     CDS             complement(<1..217)
                     /locus_tag="VU534_001351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Blp family class II bacteriocin"
                     /protein_id="HEU1513930.1"
                     /translation="MDTKMMSQFSVMDTEMLACVEGGGCNWGDFAKAGVGGGAARGLQ
                     LGIKTGTWQGAATGAAGGAILGGVAYAA"
     gene            complement(286..555)
                     /gene="blpJ"
                     /locus_tag="VU534_001352"
     CDS             complement(286..555)
                     /gene="blpJ"
                     /locus_tag="VU534_001352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpJ"
                     /protein_id="HEU1513931.1"
                     /translation="MNTKMLSQLEVMDTEMLAKVEGGYSSTDCQNALITGVTTGIITG
                     GTGAGLATLGVAGLAGAFVGAHIGAIGGGLTCLGGMVGDKLGLSW"
     gene            complement(1022..1219)
                     /gene="blpI"
                     /locus_tag="VU534_001353"
     CDS             complement(1022..1219)
                     /gene="blpI"
                     /locus_tag="VU534_001353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpI"
                     /protein_id="HEU1513932.1"
                     /translation="MNTKMMEQFSVMDNEELEIVSGGRGNLGSAIGGCIGAVLLAAAT
                     GPITGGAATLICVGSGIMSSL"
     gene            1501..2088
                     /locus_tag="VU534_001354"
     CDS             1501..2088
                     /locus_tag="VU534_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase C39"
                     /protein_id="HEU1513933.1"
                     /translation="MTSYKRTFVPQIDARDCGVAALASIAKFYGSDFSLAHLRELAKT
                     NKEGTTALGIVKAADEMGFETRPVQADKTLFDMSDVPYPFIVHVNKEGKLQHYYVVYQ
                     TKKDYLIIGDPDPSVKITKMSKERFFYEWTGVAIFLATKPSYQPHKDKKNGLLSKLPS
                     SDFQTKISHCLHCSLKLIGHYYQYRWFLLSPRNLG"
     gene            2105..2995
                     /locus_tag="VU534_001355"
     CDS             2105..2995
                     /locus_tag="VU534_001355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin ABC transporter"
                     /protein_id="HEU1513934.1"
                     /translation="MKSTLGIISVGLVITYILQQVMSFSRDYLLTVLSQRLSIDVILS
                     YIRHIFELPMSFFATRRTGEIISRFTDANSIIDALASTILSLFLDVSILILVGGVLLA
                     QNPNLFLLSLISIPIYMFIIFSFMKPFEKMNHDVMQSNSMVSSAIIEDINGIETIKSL
                     TSEENRYQNIDSEFVDYLEKSFKLSKYSILQTSLKQGTKLVLNILILWFGAQLVMSSK
                     ISIGQLITFNTLFSYFTTPMENIINLQTKLQSAKVANNRLNEVYLVESEFQVQENPVH
                     SHFLMGDIEFDDLSYKYGFG"
     gene            3011..3658
                     /locus_tag="VU534_001356"
     CDS             3011..3658
                     /locus_tag="VU534_001356"
                     /inference="COORDINATES: protein motif:HMM:NF012235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEU1513935.1"
                     /translation="MNLTIKQGDKVSLVGVSGSGKTTLAKMIVNFFEPYKGHISINHQ
                     DIKNIDKKVLRRHINYLPQQAYIFNGSILENLTLGGNHMISQEDILKACEVAEIRQDI
                     ERMPMGYQTQLSDGAGLSGGQKQRIALARALLTKSPVLILDEATSGLDVLTEKKVIDN
                     LMSLTDKTILFVAHRLSIAERTNRVIVLDQGKIIEVGSHQELMQAQGFYHHLFNK"
     gene            3669..5030
                     /locus_tag="VU534_001357"
     CDS             3669..5030
                     /locus_tag="VU534_001357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin secretion accessory protein"
                     /protein_id="HEU1513936.1"
                     /translation="MNPNLFRSVEFYQRRYHNYATVLIIPLSLLFTFILIFSLVATKE
                     ITVTSQGEIAPTSVIASIQSTSDNPILANHLVANQVVEKGDLLIKYSETMEESQKTAL
                     ATQLQRLEKQKEGLGILKQSLEKATDLFSGEDEFGYHNTFMNFTKQSHDIELGITKTN
                     TEVSNQANLSNSSSSAIEQEITKVQQQIGEYQELRDAIINNRARLPTGNPHQSILNRY
                     LVASQGQTQGTAEEPFLSQINQSIAGLESSIASLKIQQAGIGSVATYDNSLATKIEVL
                     RTQFLQTASQQQLTVENQLTELKVQLDQATQRLENNTLTSPSKGIVHLNSEFEGKNRI
                     PTGTEIAQIFPVITDTREVLITYYVSSDYLPLLDKGQTVRLKLEKIGNHGTTIIGQLQ
                     TIDQTPTRTEQGNLFKLTALAKLSNEDSKLIQYGLQGRVTSVTTKKTYFDYFKDKILT
                     HSD"
     gene            5087..5215
                     /gene="blpC"
                     /locus_tag="VU534_001358"
     CDS             5087..5215
                     /gene="blpC"
                     /locus_tag="VU534_001358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system pheromone BlpC"
                     /protein_id="HEU1513937.1"
                     /translation="MDKKQNLTSFQELTTTELNQITGGGLWEDLLYNINRYAHYIT"
     gene            complement(5286..6626)
                     /locus_tag="VU534_001359"
     CDS             complement(5286..6626)
                     /locus_tag="VU534_001359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000275284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEU1513938.1"
                     /translation="MNIAWILLYTLVTNGLEIVIFFKVDGIDLTFERIFKAFLLKILL
                     AFVFVMISYIVGNVYLSYFMEPLYGIGLSFLLLRGLPKKLLFFYGLFPMILVNLFYRG
                     VSYFVLPFLGQGQVYDGYSFTGLCIIIFNFFISLAFLKWLDYDFTSLRKEILDKAFQK
                     SLTQINWIMGGYYLVMESLSFFEYEQSIQSKTVRHLILVFYLLFFMGVIKKLDTYLKE
                     KLYERLEQEQALRYRDMERYSRHIEELYKEVRSFRHDYTNLLTSLRLGIEEEDMEQIK
                     EVYGSVLKDSSQKLQNNKYDLGRLVNIRDKALKSLLAGKFLKARDKNIVFNVEVPEEI
                     QVEGMSLLDFLTIVSILCDNAIEASVEASQPHVSIAFLKNGAQETFIIENSIKEEGID
                     ISEIFSFGASSKGEERGVGLYTVMKIVESHPNTSLNTTCQNQVFRQVLTVIHTE"
     gene            complement(6640..7377)
                     /locus_tag="VU534_001360"
     CDS             complement(6640..7377)
                     /locus_tag="VU534_001360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001219153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU1513939.1"
                     /translation="MRIFVLEDDFSQQTRIETTIEKLLKAHHIIPSSFEVFGKPDQLL
                     AEVHEKGAHQLFFLDIEIRNEEMKGLEVARKIRDRDPYALIVFVTTHSEFMPLSFRYQ
                     VSALDYIDKALSAEEFESRIETALLYANSQDSKSLAEDCFYFKSKFAQFQYPFKEVYY
                     LETSPRAHRVILYTKTDRLEFTASLEEVFKQEPRLLQCHRSFLINPANVVHLDKKEKL
                     LFFPNGGSCLIARYKVREVSEAINKLH"
     gene            complement(7382..7720)
                     /locus_tag="VU534_001361"
     CDS             complement(7382..7720)
                     /locus_tag="VU534_001361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000682119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU1513940.1"
                     /translation="MKYMIIQTQKTVYKVNIDDIYYIQTHPTKAHTVQIVTEEASFNM
                     LQNLSNLENQCGETLMRCHRNCLVNLDKLKSIDFQERILFLGEEGQYAVKYARRRYRE
                     IRQKWLKEGE"
     gene            7996..8325
                     /locus_tag="VU534_001362"
     CDS             7996..8325
                     /locus_tag="VU534_001362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase BlpT"
                     /protein_id="HEU1513941.1"
                     /translation="MTDTDPIKRAHTLITDLNKAYQACKQASADDVRFQEQLNSILGF
                     LAKAETVDNRFLIELEKFYQTSSLLMGLSALDPDAPTRAAWRAYDRFHFDQVKTKLIL
                     NENQRAN"
     gene            complement(8493..9542)
                     /locus_tag="VU534_001363"
     CDS             complement(8493..9542)
                     /locus_tag="VU534_001363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU1513942.1"
                     /translation="MKDLFLKRKQAFRKECLGYLRYVLNDHFVLFLLVLLGFLAYQYS
                     QLLQHFPENHWPILLFVGITSVLLLLWGGTATYMEAPDKLFLLVGEEEIKLHLKRQTG
                     ISLVFWLFVQTLFLLLFAPLFLAMGYGLPVFLLYVLLLGVGKYFHFCQKASKFFTETG
                     LDWDYVISQESKRKQVLLRFFALFTQVKGISNSVKRRAYLDFILKAVQKVPGKIWQNL
                     YLRSYLRNGDLFALSLRLLLLSLLAQVFIEQAWIATAVVVLFNYLLLFQLLALYHAFD
                     YQYLTQLFPLDKGQKEKGLQEVVRGLTSFVLLVELVVGLITFQEKLALLALLGAGLVL
                     LVLYLPYQVKRQMQD"
     gene            complement(9539..10270)
                     /locus_tag="VU534_001364"
     CDS             complement(9539..10270)
                     /locus_tag="VU534_001364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000889926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU1513943.1"
                     /translation="MLEIKNLTGGYVHVPVLKDVSFTVESGQLVGLIGLNGAGKSTTI
                     NEIIGLLAPYSGSININGLTLQGDATSYRKQIGYIPETPSLYEELTLREHIETVAMAY
                     GIEQKVAFERVEPLLKMFRLEQKLDWFPVHFSKGMKQKVMIICAFVVDPSLFIVDEPF
                     LGLDPLAISDLIQLLEVEKQKGKSILMSTHVLDSAEKMCDAFVILHKGEVRSKGNLLQ
                     LREAFDMPEASLNDIYLALTKEEDL"
     gene            10338..10748
                     /locus_tag="VU534_001365"
     CDS             10338..10748
                     /locus_tag="VU534_001365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HEU1513944.1"
                     /translation="MSDCIFCKIIAGEIPASKVYEDEQVLAFLDISQVTLGHTLVVPK
                     EHYRNLLEMDATSASQLFAQVPKVAQKVMKVTKAAGMNIISNCEEVAGQTVFHTHVHL
                     VPRYSADDDLKIDFIAHEPDFDKLAQVAETIKNA"
     gene            10758..11045
                     /locus_tag="VU534_001366"
     CDS             10758..11045
                     /locus_tag="VU534_001366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1513945.1"
                     /translation="MKLSNLLLFAGAAAGSYLVTKNRQTITDEVLNTTDRVQAIKDDV
                     DIIQNSLQIINQQKELIKEYQEDLTYKFKVLEKDIQTRLAVIKEMQGTEDK"
     gene            complement(11735..12871)
                     /gene="dnaJ"
                     /locus_tag="VU534_001367"
     CDS             complement(11735..12871)
                     /gene="dnaJ"
                     /locus_tag="VU534_001367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001066288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HEU1513946.1"
                     /translation="MNNTEFYDRLGVSKNASADEIKKAYRKLSKKYHPDINKEPGAED
                     KYKEVQEAYETLSDDQKRAAYDQYGAAGANGGFGGAGGFGGFNGAGGFGGFEDIFSSF
                     FGGGGSSRNPNAPRQGDDLQYRVNLTFEEAIFGTEKEVKYHREAGCRTCNGSGAKPGT
                     SPVTCGRCHGAGVINVDTQTPLGMMRRQVTCDVCHGRGKEIKYPCTTCHGTGHEKQAH
                     SVHVKIPAGVETGQQIRLAGQGEAGFNGGPYGDLYVVVSVEASDKFEREGTTIFYNLN
                     LNFVQAALGDTVDIPTVHGDVELVIPEGTQTGKKFRLRSKGAPSLRGGAVGDQYVTVN
                     VVTPTGLNDRQKVALKEFAAAGDLKVNPKKKGFFDHIKDAFDGE"
     gene            complement(13630..15453)
                     /gene="dnaK"
                     /locus_tag="VU534_001368"
     CDS             complement(13630..15453)
                     /gene="dnaK"
                     /locus_tag="VU534_001368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HEU1513947.1"
                     /translation="MSKIIGIDLGTTNSAVAVLEGTESKIIANPEGNRTTPSVVSFKN
                     GEIIVGDAAKRQAVTNPDTVISIKSKMGTSEKVSANGKEYTPQEISAMILQYLKGYAE
                     DYLGEKVTKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGLDKTDK
                     EEKILVFDLGGGTFDVSILELGDGVFDVLSTAGDNKLGGDDFDQKIIDHLVAEFKKEN
                     GIDLSTDKMAMQRLKDAAEKAKKDLSGVTSTQISLPFITAGEAGPLHLEMTLTRAKFD
                     DLTRDLVERTKVPVRQALSDAGLSLSEIDEVILVGGSTRIPAVVEAVKAETGKEPNKS
                     VNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTSK
                     SQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDIDK
                     NGIVSVKAKDLGTQKEQTIVIQSNSGLTDEEIDRMMKDAEANAEADKKRKEEVDLRNE
                     VDQAIFATEKTIKETEGKGFDAERDAAQAALDDLKKAQEDNNLDDMKTKLEALNEKAQ
                     GLAVKLYEQAAAAQQAQEGAEGAQATGNAGDDVVDGEFTEK"
     gene            complement(15942..16466)
                     /gene="grpE"
                     /locus_tag="VU534_001369"
     CDS             complement(15942..16466)
                     /gene="grpE"
                     /locus_tag="VU534_001369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000046028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HEU1513948.1"
                     /translation="MAQDIKNEEVEEVQEEEVVKTAEETTPEKSELDLANERADEFEN
                     KYLRAHAEMQNIQRRANEERQNLQRYRSQDLAKAILPSLDNLERALAVEGLTDDVKKG
                     LGMVQESLIHALKEEGIEEIAADGEFDHNYHMAIQTLPADDEHPVDTIAQVFQKGYKL
                     HDRILRPAMVVVYN"
     gene            complement(16493..17527)
                     /gene="hrcA"
                     /locus_tag="VU534_001370"
     CDS             complement(16493..17527)
                     /gene="hrcA"
                     /locus_tag="VU534_001370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HEU1513949.1"
                     /translation="MVTERQQDILNLIIDIFTKTHEPVGSKALQESINSSSATIRNDM
                     AELEKQGLLEKAHTSSGRMPSVAGFQYYVKHSLDFDRLAENEVYEIVKAFDQEFFKLE
                     DILQEAANLLTDLSGCTVVALDVEPSRQRLTAFDIVVLGQHTALAVFTLDESRTVTSQ
                     FLIPRNFLQEDLLKLKSIIQERFLGHTVLDIHYKIRTEIPQIIQRYFTTTDNVIDLFE
                     HIFKEMFNENIVMAGKVHLLNFANLAAYQFFDQPQKVALEIREGLREDQMQNVRVADG
                     QESCLADLAVISSKFLIPYRGVGILAIIGPVNLDYQQLINQVNVVNRVLTMKLTDFYR
                     YLSSNHYEVH"
     gene            complement(17691..18201)
                     /locus_tag="VU534_001371"
                     /pseudo
     CDS             complement(17691..18201)
                     /locus_tag="VU534_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001088691.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2812 domain-containing protein"
     gene            18809..21142
                     /locus_tag="VU534_001372"
     CDS             18809..21142
                     /locus_tag="VU534_001372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HEU1513950.1"
                     /translation="MVEFIKSKKEMSEEDIKANFITPAIVSKGWKNGEHIAYEEYFTD
                     GRIEVRGDKARRKEGKKSDYSLYYQFGTRIAIVEAKDNKHSVRAGLQQAIEYGEILDV
                     PFVYSSNGDGFIEHDRITREERELELDEFPTREELFSRMTKEKGLTYEITEAISTPYY
                     TDAFSMKTPRYYQQIAINRTIETVARGQKRVMFVMATGTGKTFMAFQIIHRLRKAGLA
                     KRVLFLADRNILVDQTMAEDFRPFEKVMTKITPKLLTAPEKLNSFEIYLGLYQQLTGE
                     DGTETHYQKFDKDFFDLIVIDEAHRGSAKENSNWRKVIDYFSSATQIGMTATLKETKN
                     ASNTEYFGEPIYTYSLKQGIEDGFLAPYRVMRVNLDVDVDGYRPETGKVDANGQLIED
                     RYYGRKDFDKTIVIDDRTQRVAKFVSDYMKQNNARFDKTIVFCVDIDHAERMRAALVK
                     ENLDLVQEDYRYVMQVTGDNAEGKAQLDNFMDVNSNFPAIVTTSKLLTTGVNAKTCRL
                     IVLDSNIQSMTEFKQIIGRGTRLYPQKGKEFFTIIDFRNVTNLFADPDFDGDPVKVLE
                     TGAKTVSGSTPGFVDEEGDPVEKYIVTDKQVTILNSTVQVLDENGKLITESLTDYTRK
                     NILGSYATLNDFITVWHTADKKKLILDELYKKGVYLDAIRESEGISEQEIDDFDLLLK
                     LAYGQKELTKTERINKLKQSGYLYKYSEEARAVLEILLNKYMDKGIGELESIETLKLP
                     EFQIYGGTFKIINTYFGDKKRYLQAIKELEQELFTVA"
     gene            21155..22618
                     /locus_tag="VU534_001373"
     CDS             21155..22618
                     /locus_tag="VU534_001373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000029054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent DNA methyltransferase"
                     /protein_id="HEU1513951.1"
                     /translation="MSITSFVKRIQDITRNDAGVNGDAQRIEQMSWLLFLKIYDSREM
                     VWELEEDEYESIIPEELKWRNWAHAQNGERVLTGDELLDFVNNKLFKELKELEITSNM
                     PIRKTIVKSAFEDANNYMKNGVLLRQVINVIDEVDFNSPEDRHSFNDIYEKILKDIQN
                     AGNSGEFYTPRAATDFIAEVLDPKLGESMADLACGTGGFLTSTLNRLSSQRKTSEDTK
                     KYNTAVFGIEKKAFPHLLAVTNLFLHEIDDPKIVHGNTLEKNVREYTDDEKFDIIMMN
                     PPFGGSELETIKNNFPAELRSSETADLFMAVIMYRLKENGRVGVILPDGFLFGEGVKT
                     RLKQKLVDEFNLHTIIRLPHSVFAPYTGIHTNILFFDKTKKTEETWFYRLDMPDGYKN
                     FSKTKPMKSEHFNPVRDWWENREEILEGKFYKSKSFTPSELAELNYNLDQCDFPKEEE
                     EILNPFELIQNYQAERATLNHKIDNVLADILQLLEDK"
     gene            22618..>23310
                     /locus_tag="VU534_001374"
     CDS             22618..>23310
                     /locus_tag="VU534_001374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEU1513952.1"
                     /translation="MTPEQLKASILQRAMEGKLVPQNPNDEPASELLKRIKAEKEKLI
                     SEGKIKRDKKETEIFRGDDGKHYGKFADGSTQEIDVPYDIPDTWEWVRFSTLVEIVRG
                     GSPRPIKDYLTSEVDGINWIKIGDTEKGEKYINNVKEKIKKSGLNKTRFVKKGTFLLT
                     NSMSFGRPYILNVDGAIHDGWLAISNYENSLNKDYLFYILSSNVVYSQFLSLISGAVV
                     KNLNSDKVASILI"
BASE COUNT         7429 a         4715 c         4228 g         6938 t
ORIGIN      
        1 ttgctgcata ggctacacct ccaagtatag ctccacccgc agcaccagtt gctgcacctt
       61 gccatgttcc tgttttaatg cctagttgaa gacctcttgc tgctcctcct ccaacacctg
      121 ctttggcaaa atctccccaa ttgcatccgc caccttcaac gcaagcaagc atttcagtat
      181 ccataacaga aaattgtgac atcatttttg tatccatgac aaatactcct tttttaaaaa
      241 actaaaataa atcagaatag aatcctcata attttactat aagtcttacc aacttagtcc
      301 caatttatca ccaaccatac ctcctaagca tgttaatcca cccccaattg caccaatgtg
      361 tgctccaaca aatgcaccag caagtccagc tactcctaaa gtggccaaac ctgctccagt
      421 tccaccagtt ataattcccg tagtgactcc tgtaatcagt gcattttgac aatcagtgga
      481 gctatacccc ccttcaactt tcgcaagcat ttcagtatcc ataacctcta actgtgacaa
      541 catttttgta ttcatgatga atacctcctt tttattttca atttgttacc aaagtcttaa
      601 attcaataaa caaatagatt ttttatagta tctttttgat tttcttaaaa aagtatatac
      661 gtctactatc ttcttaaagg tagcagtacc tattttttag tctaagattt caataatctt
      721 gagtatctaa aatatcttaa tttcgttatt ctccttgcaa taaaaagttt tactatacta
      781 tttattaact tgcagaaagc aaaaaatatt agtaaataat agtttatagt taagtttttt
      841 attcctacca atccatcaac taagtaaagc atcaacgatt acataaacga ttgataatat
      901 aattaaaatt ttgctaacta tcttattctc atcattctta gataactttg atattttgta
      961 agtaagtaaa taagacagta aattaatagc gataataata ctatatttaa gaatcataat
     1021 cttacaaaga ggacataatt cctgaaccta cacaaataag tgttgctgct cccccagtta
     1081 tcggaccagt cgcagcagct aatagtactg ctccaataca accaccgatt gcagatccta
     1141 aattgcctct tcctccacta actatttcga gttcttcatt atccataaca gaaaattgtt
     1201 ccatcatttt tgtattcatg acaaatactc cttttttctt tttttatttt tgtcttgttg
     1261 taactttgat aagtttagta tatcatcgtt ttttaaaatt tttcatccag atcttgaatt
     1321 gtcatcgaaa cgtcttgaat tagctttttt atttcaagcc acctctaaat gtttaaaaaa
     1381 aataatttct aatcactttt ttaccattca ggaagtttta atgactattc aagatttcat
     1441 aaaatatgaa cttagtttta tgacataata gacctatcca ctatatgaaa ggaattgcca
     1501 atgacttctt ataaacgtac atttgttcct caaatagatg cgagagactg tggtgtcgct
     1561 gccttagcct cgattgctaa attctatggt tcagattttt ctctagctca cttgagagaa
     1621 cttgcaaaga ccaataaaga agggacgact gctcttggca ttgtaaaagc cgctgatgaa
     1681 atgggctttg aaacaagacc tgttcaagca gataaaacgc tctttgacat gagtgatgtc
     1741 ccctatccat ttatcgttca cgttaacaaa gaaggaaaac tccaacatta ctatgttgtc
     1801 tatcaaacaa agaaagacta tctgattatt ggtgatcctg acccttctgt aaaaatcact
     1861 aaaatgtcaa aagaacgctt tttctatgaa tggactggag tagctatttt tctagctacc
     1921 aaacccagct atcaacccca taaagataaa aagaatggtc tactaagcaa gcttccttcc
     1981 tctgattttc aaacaaaaat ctctcattgc ttacattgtt ctctcaagct tattggtcac
     2041 tattatcaat ataggtggtt cttactatct ccaaggaatc ttggatgaat acattccaaa
     2101 tcagatgaaa tcaactttag gaatcatctc agttggtctg gttatcacct atatcctcca
     2161 acaagtcatg agcttctcca gagattatct cctaaccgtt ctgagtcaga gattaagtat
     2221 tgatgtgatt ttatcctata ttcgccatat ttttgaactt cccatgtctt tctttgcgac
     2281 acgtcgtaca ggagaaatca tttcacgatt cacagatgct aactctatta tagatgcctt
     2341 ggcttctacc attctttctc tttttctgga tgtttctatt ctgattcttg taggaggcgt
     2401 cttactggca caaaacccta atctcttcct tctttctctt atttccattc ctatatacat
     2461 gttcatcatc ttttctttta tgaaaccttt cgaaaaaatg aaccatgatg tcatgcaaag
     2521 taattctatg gttagctctg ccattatcga agatatcaac gggattgaaa ctataaagtc
     2581 gctcacgagt gaagaaaatc gctatcaaaa tatagacagc gaatttgtag attatttgga
     2641 aaaatccttt aagctcagta aatattctat tttacaaacg agtttaaagc agggaacaaa
     2701 attagttctg aatatcctta tcctatggtt tggcgctcaa ttagtcatgt caagtaaaat
     2761 ttctatcggt cagctgatta cctttaacac acttttttct tactttacaa ctcctatgga
     2821 aaatattatc aacctccaaa ccaaactcca atctgcgaag gtcgctaata accgtttgaa
     2881 cgaagtctat ctagtcgaat ctgaatttca agttcaagaa aaccctgttc attcacattt
     2941 tttgatgggc gatattgaat ttgatgacct ttcttataag tatggttttg gatgagatac
     3001 cttaacagat attaatctca cgattaaaca aggagataag gttagcctag ttggagttag
     3061 tggttctggt aaaacaactt tagccaaaat gattgtcaat ttctttgaac cctacaaagg
     3121 gcatatttcc atcaatcatc aggatattaa aaacattgat aaaaaagtct tgcgccgtca
     3181 tattaattac ctaccccaac aagcctatat ctttaatggc tctattttgg aaaacttaac
     3241 cttgggcggt aatcatatga ttagtcaaga agatattcta aaagcttgtg aagtagctga
     3301 aatccgtcaa gacattgaaa gaatgcctat gggctatcaa actcagctct ctgatggagc
     3361 tggtctatca ggaggacaga agcaacgaat cgctctcgct cgtgctcttt taactaaatc
     3421 tcctgtttta atactagatg aagctactag cggtcttgat gtcttgactg agaaaaaggt
     3481 tatagataat cttatgtctc taactgataa aaccattctc tttgtagccc atcgtctcag
     3541 tatagccgaa cgaaccaacc gtgtcattgt tcttgaccag gggaaaatca ttgaagttgg
     3601 tagtcaccaa gagttaatgc aggcgcaagg tttctaccat catctattca ataaataagg
     3661 agaatgtcat gaatcctaat ctttttagaa gcgtcgagtt ttatcagaga cgttaccata
     3721 actatgcgac agtgttaatt atacctcttt cattactatt tactttcatc ttgattttct
     3781 cccttgttgc cacaaaagaa attactgtta cttcccaagg agaaatcgcc cctacaagtg
     3841 tcattgcctc cattcagtca accagtgata atcctatcct agctaatcat ttagtggcaa
     3901 atcaagtagt tgaaaaaggg gacttactca tcaaatactc tgaaacaatg gaagaaagtc
     3961 agaaaactgc cttagcaact caattacaaa gacttgagaa gcaaaaagaa ggacttggaa
     4021 ttttgaaaca aagcttagaa aaagcgactg atcttttttc tggcgaggat gaatttggct
     4081 accataatac ctttatgaat tttactaaac aatcccatga tattgaactg ggtatcacaa
     4141 agactaacac cgaagtttca aatcaagcta atctttccaa tagcagttca tcagctattg
     4201 aacaagaaat tacaaaagtt caacaacaaa ttggagaata tcaagagttg agagatgcta
     4261 tcataaataa cagagcacgc ttaccaactg gcaatccgca ccagtcaatt ttgaatcgtt
     4321 atcttgtagc ctcacaagga caaacacaag gaactgcaga ggagccattt ttatctcaaa
     4381 ttaatcaaag tattgcaggt cttgaatcat ctatcgcaag cctcaaaatt cagcaagctg
     4441 gtatcggaag tgtagcaact tatgataaca gtttagcaac caaaattgaa gtactccgca
     4501 ctcagttttt acagacagcc tcacagcaac aactaactgt ggagaatcaa ttaacagaat
     4561 taaaagtaca actagatcaa gccacacagc gtttggaaaa caatacctta acctccccaa
     4621 gtaaaggtat cgttcatctg aacagcgaat ttgaaggtaa aaatagaatt ccaactggta
     4681 cagaaattgc tcaaatattc cctgtcatca cagatacaag agaagtacta atcacttact
     4741 acgtatcttc tgactatcta cctctactag ataaaggaca aactgtaaga ttaaaactgg
     4801 agaagattgg aaatcacggc accaccatca tcggccaact tcagacaatt gatcaaactc
     4861 ctaccagaac agagcaagga aatctcttta aattaaccgc tcttgcaaaa ctatctaacg
     4921 aggatagtaa actcatccaa tatggcttac aaggtcgcgt cactagtgta actacaaaga
     4981 aaacatattt tgattatttc aaagataaaa ttttaacaca ttctgattaa ttttcagata
     5041 acactctata actatttatt atcttatcaa aaaggagaat cataacatgg ataagaaaca
     5101 aaacctaact tcatttcaag aactaacaac taccgaactc aatcaaatta caggtggagg
     5161 attgtgggaa gatttattat ataacattaa tagatatgct cattacatca cataagaact
     5221 tcatcatcca atacaactat aaaaaaataa gaccgagaaa caagtactct cggtcttatt
     5281 tttcatcatt ctgtatgtat cacagtaagt acctgacgaa agacttgatt ttgacaggtg
     5341 gtatttagac tggtattagg atggctttcc acaatcttca tgacggtata gagaccaact
     5401 cctctctcct cccctttaga actggctcca aaggagaaga tttcagaaat atcgatgccc
     5461 tcttctttga tggagttttc gatgataaag gtctcctgtg ctccattttt taaaaaggcg
     5521 attgaaacat gaggttgact agcttccaca ctggcttcaa tagcattgtc acaaaggata
     5581 gacacaatgg ttagaaaatc aagtagactc atcccctcga cctgaatctc ctcaggaact
     5641 tcgacattaa agacaatgtt cttatctctg gcttttaaaa atttccctgc tagaagactt
     5701 ttgagggctt tatcacgaat atttaccaat ctgcccaggt catatttatt gttctgcaat
     5761 ttctgactgg aatcctttaa gacggagcca tagacctctt ttatctgctc catatcctcc
     5821 tcttcaatgc ccagacgtaa gctagtcaag aggttggtat aatcatgacg aaagctccgt
     5881 acttccttgt aaagctcctc tatatgccga ctatagcgtt ccatatctct atagcgcagg
     5941 gcctgctctt gttccaatct ctcatagagt ttttccttca aataggtatc caatttcttg
     6001 ataaccccca taaaaaagag taggtaaaag actaggatga gatggcgaac agtctttgat
     6061 tgaatacttt gttcatattc aaaaaaagac agactttcca tgactagata gtagccaccc
     6121 attatccagt taatctgagt cagggacttt tgaaaggctt tatcgagaat ctcctttctc
     6181 aagctagtaa aatcgtagtc caaccatttc aaaaaagcta gagaaatgaa gaaattgaaa
     6241 attattatac ataacccagt aaatgagtag ccatcatata cttgcccttg tcccaaaaat
     6301 ggaagcacaa aataggagac tcctctataa aagagattca ccaatatcat tggaaagaga
     6361 ccataaaaga aaaggagttt tttaggaagc cctctcaata ataagaaaga taagcctatg
     6421 ccgtacaagg gttccataaa ataagatagg taaacatttc ctactatata gctaatcatc
     6481 acaaaaacaa aggccaacag tatcttcaaa agaaaggcct taaaaatcct ctcgaaagta
     6541 agatcaattc catccacctt aaagaagatg acaatttcta gtccattagt aacaagtgta
     6601 tacaacaata tccaagcaat gttcataaat tctcctagct cagtgtaatt tattgatggc
     6661 ctcagacact tccctgacct tataacgggc gattagacaa cttccaccat tgggaaagaa
     6721 aagcagtttt tctttcttat ccaaatgcac cacatttgca ggattgatga gaaaagagcg
     6781 gtggcactgc aagagacggg gctcctgctt gaaaacctcc tctaaactcg ctgtaaattc
     6841 cagcctgtct gtcttggtat agagaataac acgatgggct ctgggcgacg tttcgagata
     6901 gtaaacctct ttaaaaggat actgaaattg ggcaaatttt gatttaaagt aaaagcaatc
     6961 ttccgccaga cttttactat cttgactatt ggcatagagg agggctgtct cgatccgaga
     7021 ttcaaactcc tctgctgaca aggccttatc aatgtagtcc aaagcagaca cttggtagcg
     7081 aaaagacagg ggcataaact ccgagtgagt cgtcacaaag acaatcaggg cataaggatc
     7141 ccgatcccga atctttctag ccacttccag tcccttcatc tcttcatttc gaatctcaat
     7201 atccaaaaag aatagctgat gggccccctt ctcatgcact tcagccagca gttggtccgg
     7261 cttgccaaat acctcaaaag agctaggaat gatatgatgt gctttcaaaa gtttctcaat
     7321 cgtcgtttca attctagtct gttgggaaaa atcatcctct aaaacaaata ttctcatctt
     7381 cttactctcc ctctttcaac catttttgac gaatttctct atagcgacgt ctggcatact
     7441 tgacagcgta ttgaccttct tctccgagaa aaaggattct ttcttgaaaa tcaatcgatt
     7501 ttaatttatc aagattaacc aaacaatttc gatgacatct catcaaggtt tccccacatt
     7561 ggttctcaag attacttaaa ttttgaagca tattaaaact agcttcttct gtaacaatct
     7621 gtacggtatg ggctttagtt ggatgtgttt ggatatagta gatatcgtcg atgtttactt
     7681 tatagactgt tttctgcgtc tgaataatca tatatttcat tggattctcc tcctaagaaa
     7741 agaataacag aaaaggtcta gcccaagcac acccaatcct aaacagtctt tgaaaactcc
     7801 taaaaggatt attttctaca acatcatgat gagcttacaa ctattttatc ataaaattca
     7861 ctcagcgcaa ttcaagacat ttcaatgaca attaaagatt tgaataaaaa aaaagaatta
     7921 aaagtgataa actaacagta tcaaaacaca gttgccagaa gtaagactgg cacccagatt
     7981 aaaggaggca ttcccatgac agatacagac cccatcaaaa gagctcatac tttgattact
     8041 gacttaaaca aagcctacca agcatgcaaa caggcaagcg ctgacgacgt ccgctttcag
     8101 gagcaattaa actctattct tggttttcta gccaaggctg aaacagtgga taatcgattc
     8161 ttgattgaac tagaaaaatt ttaccagact tccagtcttc tcatgggact cagcgctctt
     8221 gatccagatg ctccaactcg cgccgcttgg cgggcctatg accgcttcca ctttgaccaa
     8281 gtcaagacca agttaatact caatgaaaat caaagagcaa actaggaagc tagccgcaag
     8341 ctgtacttga gtacggtaag acgacgctga cgtggtttga agagattttc gaagagtata
     8401 agtctctacg gaccaaccat tatcctgtag taacaaaaaa gaagttgaga cagactgaac
     8461 tcaacttctt ttttagtgtc gtatcagcaa tgttagtcct gcatctgacg ttttacctga
     8521 taaggcaaat acaagactag taaaaccaaa ccagctccta gtaaggctag aagggctagt
     8581 ttttcttgga aggtaatcaa cccaacaact aattccacaa gtaaaacaaa actggtcaat
     8641 cctcgaacta cctcctgtaa gcctttttcc ttttgcccct tgtccagcgg aaagagttgg
     8701 gtcaaatact ggtagtcaaa ggcatgatag agggccagca actggaagag caagaggtag
     8761 ttaaagagaa ctaccactgc tgtcgcaatc caagcttgct cgataaaaac ctgcgccagc
     8821 aaggaaagca agagaagacg aagactgaga gcaaagaggt cgccatttcg cagataagaa
     8881 cgcagataga gattttgcca aatcttccca ggcaccttct gaacagcctt taaaataaag
     8941 tccagatagg cacgacgctt aacgctgttt gaaattccct tgacctgcgt aaagagggca
     9001 aagaaacgaa gcaagacttg cttacgcttg ctttcttgag aaataacata gtcccagtcc
     9061 agtccagttt cagtgaaaaa tttgctggcc ttttgacaaa agtggaaata ttttcctacc
     9121 cccaataaaa gcacatagag cagaaaaact ggcaagccat aacccattgc taaaaataaa
     9181 ggcgcaaata acagcaagaa aagggtctgt acaaagagcc aaaagactag ggaaatgcca
     9241 gtttgacgct tgagatggag cttaatttcc tcttctccaa ctaagagaaa gagcttgtct
     9301 ggagcctcca tataggtggc agttcctccc caaagtaaaa gtaaaacaga cgtaattcct
     9361 acaaacaaaa ggataggcca atgattttca ggaaaatgtt gtaagagttg actgtactgg
     9421 taggctagaa agcccaacag gacaagcagg aacaagacaa agtggtcatt gagcacatag
     9481 cgcagataac caagacactc cttacgaaag gcctgctttc tctttaaaaa caagtctttc
     9541 atagatcctc ctctttggtc agagccaagt aaatatcatt caaactagcc tcaggcatat
     9601 caaaggcttc acgtagttgc aggagattgc ctttggaacg cacctctccc ttgtgaagaa
     9661 tgacaaaggc atcacacatc ttctccgccg aatccagcac gtgggtactc atgagaatag
     9721 acttgccctt ttgcttctcc acttccaaaa gctgaatcaa atcagaaata gccagcggat
     9781 caagaccaag gaaaggctca tccacgatga aaagacttgg atccaccaca aaagcacaga
     9841 taatcatgac cttctgcttc atcccttttg aaaaatgaac agggaaccag tctaatttct
     9901 gttccaaacg gaacattttt aacaagggct ctactcgttc gaaagccact ttttgctcaa
     9961 taccgtaagc catagcaacc gtttcgatat gctctctgag ggtcaattcc tcatacagac
    10021 taggcgtctc aggaatgtag ccaatctgct tgcggtagct agtcgcatct ccttgcagag
    10081 tcaggccatt gatattgatg gagccactat aaggtgccaa cagaccgata atctcattga
    10141 tcgtcgttga tttcccagca ccattgagac caatcaaacc gaccaactgc ccactttcaa
    10201 cagtaaagga cacatctttc aaaacaggaa catgaacata gccacctgtc aggtttttaa
    10261 tttctaacat attttctcca aatctggtat aatgtagcta tattatatca aaattcagta
    10321 cagtagaggt agattttatg tcagattgca ttttttgtaa aatcatcgca ggggaaattc
    10381 ctgcttcaaa agtatatgaa gatgagcagg tccttgcctt tcttgatatc tctcaagtaa
    10441 cactaggaca caccttggtc gtgccaaaag aacactatcg caatcttttg gagatggatg
    10501 ctacgagcgc cagccaactc tttgcccaag taccaaaagt agctcaaaaa gtcatgaaag
    10561 tcactaaggc tgctggtatg aatatcattt ccaactgtga agaagtcgct ggtcaaacag
    10621 tttttcatac tcacgttcac cttgtgcctc gctacagtgc tgacgatgac ctcaagattg
    10681 attttatcgc ccacgaacca gactttgaca aacttgctca agtcgctgaa accatcaaaa
    10741 acgcttaagg agttgctatg aaattatcca acctactgct atttgcagga gctgcagccg
    10801 gaagttatct ggttacaaaa aatcgccaaa ccatcacaga tgaagtcttg aataccactg
    10861 accgcgttca agctatcaag gacgatgtgg atattatcca aaacagcctg caaatcatta
    10921 accagcaaaa agaacttatc aaggaatacc aagaagactt gacttacaag tttaaggtct
    10981 tggaaaagga tatccagact agactagctg tgataaaaga aatgcaggga actgaagata
    11041 agtaaaaaga gcccgacggc tcttttttaa aacgtaaaca agttatagtg aattgaattt
    11101 agaatagcac accatagttt ctaaagcatt gttagagatt actttaaaat cctcttatca
    11161 atttgttcat attctatttc aatctattat atatatccca tcaactatgc atcataattt
    11221 aggtaattca tactcaataa aaatcaaaaa gcaaactaga aagctaggca cagactgctc
    11281 aaaacaccgt tttaaggttg tggatagaac tgacgaagtc agctcaaaca ctgttttgag
    11341 gttgtggata gaactgacga agtcagtaac catacccatg acaagccgac gctgacgtgg
    11401 tttgaagaaa tttttgaaga gtatcattca ccatttcaca actaaatcga agactttctg
    11461 ccgtaatgaa aacacctgaa acagcttggt ttcagctgtc cggaaacttt aaaacttagg
    11521 ttcaaagttt aggtatggaa cttcgaagga ggtcactacc gtccgtcatt acttaggaaa
    11581 gtcttaaaaa atctataaag taaaaagcaa actaggaaac tagccacggg ctgctcaaaa
    11641 cactattttg aggttgtaga tacgactgac gaagtcagtc acatatatac ggcaaggcaa
    11701 cgctgacgtg gtttgaagag attttcgaag agtattattc tccatcaaag gcatctttaa
    11761 tatggtcaaa gaagcctttt ttctttggat ttactttcaa gtcaccagca gccgcgaatt
    11821 ctttcaaggc tactttttgg cggtcgttca agcctgtcgg tgttacgaca ttaacagtaa
    11881 cgtattggtc accaactgca ccgccacgaa ggctcggtgc ccccttacta cgtaggcgga
    11941 acttcttacc agtctgagtt ccctctggaa taaccaattc aacatcaccg tgaacagttg
    12001 gaatatctac tgtatcacca agagccgctt ggacaaagtt gaggttgaga ttgtagaaga
    12061 tagtcgttcc ttcacgttca aacttgtcgc tagcttccac agaaactact acatacaagt
    12121 caccataagg tccaccgtta aagcctgctt caccttgacc agcgaggcga atttgttgac
    12181 ctgtttccac accagcaggg attttcacat gtacgctatg agcttgtttc tcatgacctg
    12241 ttccatgaca ggttgtacat ggatatttga tttcttttcc tcgaccgtga cagacatcac
    12301 aggttacttg gcgacgcatc ataccaagag gagtctgcgt atcgacgtta atgacaccag
    12361 cgccatgaca gcgtccacaa gtgactggac ttgtccctgg cttagcacca gatccattac
    12421 atgtacgaca gccagcttca cgatgatact taacttcctt ctcagttccg aagatagctt
    12481 cttcaaaggt caaattgaca cgatactgga gatcatctcc ttggcgagga gcgtttggat
    12541 tgcgcgaaga accgcctccg ccgaagaaac ttgagaaaat atcctcaaaa ccaccgaagc
    12601 cacctgcccc attgaaaccg ccgaaaccac cagctccacc aaaaccacca ttggcgcctg
    12661 cagcaccata ctggtcatag gcagcacgtt tttggtcgtc actcaaagtc tcataggctt
    12721 cttgaacttc cttgtacttg tcctcagcac caggctcctt gttgatatct gggtgatatt
    12781 ttttggaaag cttacgataa gcctttttga tttcgtctgc cgaagcgttt ttggataccc
    12841 ccagacgatc ataaaattca gtattgttca taattcaaga tacaaagggc gtcaaacgga
    12901 cacagccatc taggagtttt gacgacggac gcttacgtcc tagaaaaaac tatctttttg
    12961 gcacagtcca tagcccgtgt tcagttacga acacccttat tcctttctat tgatgttctg
    13021 aatcgaacca ccatttaggt cgggttcaat tcctttcttt tatatttagt aagaaattct
    13081 gaaacccgtg ttcagttacg aacactcttt gttcctttct attgatgaga caaaacccaa
    13141 acaaatgaga ttccgtccct ttttatcgaa aaacagaggc tgggttgcaa cctctgcaaa
    13201 taagtaaatt aactttattt tgattttaaa tatcctataa gtacagaaat atttatatat
    13261 ttttgtctct tcttagtatt tgcctatata attccaattg atcataagaa atacaactac
    13321 tgtccaaatc ataccaatta tgaacggtat tacaaattta tatgtttgta tttctaatga
    13381 tatcatagct ggtaccatcg ccgatacaaa tgcagacaac aatactgagg taacaaaatt
    13441 ccttaccgct tcatcatttt tgatacaact atcatgttca gctaatataa ttctctatat
    13501 ctagctaaat attctattgg aatattatca ataaaatctt ttgatgttct atagttatca
    13561 gcttgattac aaaaatcatt ataaactttt cgtgtatttt ttagatactc ttcatccaat
    13621 acactcatct tacttttccg taaactctcc gtctacgacg tcatcgcctg cgttccctgt
    13681 tgcttgtgcg ccttctgctc cttcttgagc ttgttgcgct gctgcggctt gttcgtagag
    13741 tttaacagca agtccttgag ctttttcgtt caatgcttca agttttgttt tcatgtcgtc
    13801 caagttgttg tcttcttgag ctttcttaag gtcatcaagg gcagcttggg cagcgtcacg
    13861 ttctgcgtcg aagcctttac cttcagtttc cttgattgtc ttttcagtcg caaagattgc
    13921 ttggtctact tcattacgaa ggtctacttc ttctttacgt ttcttatcgg cttcagcgtt
    13981 tgcttctgca tctttcatca tgcggtcgat ttcttcgtca gtcaaacctg agttcgattg
    14041 gatgacaata gtttgttctt tttgagttcc aaggtctttg gccttaacag acacgatacc
    14101 gttcttgtcg atgtcaaatg ttacttcgat ttgaggaatt ccacgaggtg cagctgggat
    14161 atcagtcaat tggaagcgtc caagagtctt gttatctgct gccattgggc gttcaccttg
    14221 aagaacgtgg atatcaacgg ctggttggtt gtctgctgct gttgagaaga cttgtgattt
    14281 agatgttggg attgtagtgt tgcgatcgat aagttttgta aatactccac ccattgtttc
    14341 gataccaagt gacaatggcg ttacatcaag aaggacaacg tccttgacat caccagtaat
    14401 cacaccacct tggatagccg cacccatagc aactacttca tcagggttta ctgatttgtt
    14461 tggttcttta ccagtttcag ctttaacagc ttcaacaacg gcagggatac gagttgaacc
    14521 accaacaagg ataacttcgt cgatttctga caagctcaaa cctgcatctg aaagggcttg
    14581 acgaactgga acttttgtac gttcaacaag gtcacgagtc aaatcgtcaa atttcgcacg
    14641 agtcaaagtc atttccaagt gaagaggtcc agcctcacct gcagtgataa atggcaagct
    14701 gatttgtgtt gaagttacac cagaaaggtc tttcttcgct ttttcagccg catctttcaa
    14761 acgttgcatt gccatcttgt cagtagacaa gtcgataccg ttttctttct tgaattctgc
    14821 taccaagtgg tcaatgattt tttggtcaaa gtcgtcacca ccaagtttgt tgtcccctgc
    14881 agttgacaat acgtcgaaga caccgtcacc caattcaagg atagagacgt cgaatgtacc
    14941 accaccaagg tcaaatacca agattttttc ttctttgtca gtcttgtcca aaccataagc
    15001 aagagctgct gcagttggtt cgttaacaat acgttctact tcaagaccag caattttacc
    15061 agcgtctttt gttgcttgac gttgagcgtc gttgaagtaa gccggaactg tgataacagc
    15121 tttggttact ttctcaccaa ggtagtcttc agcgtagcct ttcaagtatt gaaggatcat
    15181 agctgagatt tcttgtggag tgtattcttt tccatttgca gaaacttttt cagaagttcc
    15241 catcttagat ttgatagaga taactgtatc tgggtttgta actgcttgac gttttgcagc
    15301 atcaccaacg atgatttctc cgtttttgaa tgagactaca gatggagttg tgcggtttcc
    15361 ttctgggttt gcgatgattt tgctttcagt tccttcaaga actgcaactg ctgagtttgt
    15421 tgtacctaag tcaataccga taattttaga catgtgtttt tctccttgtt agttaatttt
    15481 ctatttttct ttttgatact cttcttaagt ggcgacagtg gcgacgccgt cagagcttga
    15541 cttcgtcaat ctctttgact aaactttgag cctaaggtct caaaatttgc gcaaatagcg
    15601 ccacggcgaa gagtatcgtg tttggttcgc ttcgctcact attacaaagc caaacatatt
    15661 ttatctttct tcatagttta ttgtcgtttc ggacaagttt tctattatgt aaattgcgac
    15721 acgaggagtc gaaatcgatt ttatttcgac gacgagttag taaggaagct aggcaaacgc
    15781 catagcgatt gccgttttct gacgagttgc tttagctacc gtcagaattg ccgaatcgaa
    15841 cacgccctaa gctctgagta aaaaagatag attttcttgt gttcatcgaa cacttcgtca
    15901 atctcctatt tttactgcga gctttttacg ggctttatat cttagttata caccactacc
    15961 attgctgggc gtaggatgcg gtcatggagt ttgtagcctt tttgaaagac ttgagcgatg
    16021 gtatctactg ggtgttcatc gtctgctggg agagtttgga tggccatatg gtagttatgg
    16081 tcaaattcgc catctgctgc gatttcttca attccttctt ctttcaaagc gtgaatcaag
    16141 ctttcttgca ccatccccaa gcccttcttc acatcatctg tcaaaccttc aactgcaagt
    16201 gcacgctcaa ggttgtcaag agatggtaag attgcttttg ccaagtcctg gctacgataa
    16261 cgttgcaagt tttgacgttc ttcattggca cggcgttgga tattttgcat ttctgcatga
    16321 gcgcgaagat atttgttttc gaactcatct gcacgttcat ttgccaagtc caactcagac
    16381 ttttcaggag ttgtttcttc agctgttttc acaacttcct cttcttgaac ttcttctact
    16441 tcttcatttt ttatatcttg ggccatgttc gcctccttta atgatttcaa tcttaatgta
    16501 cttcgtaatg attactgctg aggtagcggt aaaaatctgt caacttcatg gtcaaaacac
    16561 ggttgaccac attgacttga ttgattagct gttggtaatc cagattaact ggaccgataa
    16621 tggctagaat tccaactccc cgataaggaa tgaggaactt actactgatt accgctaggt
    16681 cagctaaaca ggactcttga ccgtctgcaa cacgaacatt ttgcatctga tcctcacgca
    16741 acccctcacg aatctccaag gccacctttt gcggttggtc aaagaactga taggctgcta
    16801 gattggcaaa attcaagaga tggaccttgc ccgccatcac aatgttttcg ttgaacattt
    16861 ccttaaagat gtgttcaaag agatcgatga cattatccgt tgttgtaaag taacgctgga
    16921 taatctgcgg aatctccgtc cgaatcttgt agtgaatatc taaaacggtg tgaccgagga
    16981 aacgttcctg aatgatgctc ttcagtttca gcaaatcctc ctgcaagaag ttccttggaa
    17041 tcagaaactg actagtaacc gttcgcgact cgtctagggt aaataccgcc aaggctgtat
    17101 gttgccccaa aacaacgata tcaaaggctg tcaaacgttg cctgctcggc tcaacatcca
    17161 gtgccactac cgtacagcca ctcaggtctg ttagtaagtt agcagcctct tgcagaatat
    17221 cctccaattt gaagaattcc tgatcaaagg ctttgacaat ctcatatacc tcattttcag
    17281 ccagccggtc aaaatccagt gagtgtttca catagtactg aaaaccagca acacttggca
    17341 tccgaccact tgaagtatga gccttctcaa gcaacccttg tttttctagt tccgccatgt
    17401 cattacgaat ggttgcactg ctagagttaa tagactcttg caaggctttt gatccgacag
    17461 gttcgtgcgt tttggtaaag atgtcaataa tcagatttaa aatatcctgc tgacgctctg
    17521 taaccatctc atcactcctc tctgtctgat caattagcac tcaatgcatc caagtgctaa
    17581 ctcatgattc tattatacac ccttagaaga gaatgtcaag acaaaaactc aaaaaattag
    17641 cactctttta tcaagagtgc taaaaatcaa tctgaagacc tagaaccttg ctattcatct
    17701 actcggtatt tcctttttag tctgaaataa ccataaatta gataagaaat cagaaaagca
    17761 tataaaacaa aaataagaaa gaaagacata gaaagatcct ctctaaacaa actcatacaa
    17821 acaacaagac cacctgagaa agtagctgta caggaacgaa gtctagatcg cataacttcc
    17881 catttgagcc ctttactcat atagacttga tcctctggaa gtaaatcaga agacgattta
    17941 cgaagaatcg aacaagaacc tgctcctatc aattcccaac ctctatctct aaaatcttgc
    18001 agttcatgct tatacttttt taagaaatct agaatcatag atacggtaga tgacatcgtc
    18061 tggttgacat tggtcaaaat agaacaaacc aaaacgactc gttctatacc tccaaccttt
    18121 caaatgcatc tcatgtaaat gttcttcttc cttgtccaaa tcaacaatgg tgaaaatccg
    18181 aaattctact ctgctattca ttgtcttacc ccaaaattag aaaacatgcc tggcgttatt
    18241 tattagataa ttctttccac ttttgactca atctccaaaa aatataagaa atctgaatcg
    18301 caaaaactat caataaaacc caatctatta tgaaaatcaa aaacactttc caactgaaag
    18361 aactacctcc agtgacaaac tttgagaaaa acggtagtag agctaaaaag agaaataaaa
    18421 taggaagcat ccgcattgtt aaaatccgtt tggcataaaa aaatctttat ttaaactaaa
    18481 atattatggc aaaatttacg ccagtttttg aacggctgat gtagatattt tatactttca
    18541 aaatgtttaa atgtgattat ttatttttga aaaatagatc accagcccga ctgaaagtgc
    18601 ttatagaatg ataataagtc gcctgccgaa aacagcgaaa aatagcggtg ttatgcggag
    18661 ataatctgac gcgatgcgaa agtatattgc atacttattt tcaacaattt agcagagtat
    18721 ttttataagt gtgatataat agaagtataa tttgttctga tagtttattt tatggagaag
    18781 tagattttta gaatgcggag ggttcaatat ggttgagttt ataaagtcta agaaagaaat
    18841 gagtgaggag gatattaaag caaatttcat cactcctgct attgtatcca aaggatggaa
    18901 aaatggtgag catatcgctt acgaagaata cttcactgat ggtcgaattg aagttagagg
    18961 agataaggct cgtcgtaaag aaggaaaaaa atcagactat tcactgtatt accaatttgg
    19021 aactcgaatt gcaattgttg aggcaaagga taataaacac agcgttcgag caggattaca
    19081 acaagctatt gaatatggag agattttaga tgttccattt gtttattctt cgaatggtga
    19141 tggctttatt gaacacgacc gtatcacgag agaagaacgt gagctggagt tagacgaatt
    19201 ccctactcgt gaagaattat tttctcgtat gacgaaggaa aaaggattga cgtacgaaat
    19261 tacagaagct atctcaactc catactatac agacgccttc tcaatgaaaa cgccacgcta
    19321 ttatcagcaa atagctatca accgtactat tgaaacagtt gccagaggac aaaaacgagt
    19381 aatgtttgtg atggcaacag gaacggggaa aacgttcatg gcttttcaaa ttattcatcg
    19441 ccttcgaaaa gctggtttgg ctaaacgagt tttattctta gcagatagaa acatcttagt
    19501 agaccaaacg atggctgaag actttaggcc attcgaaaag gtaatgacga aaattacacc
    19561 aaaacttttg actgctcctg aaaaattaaa ttcttttgaa atttatctag ggctttatca
    19621 gcaactaact ggtgaagatg gaactgaaac acattatcaa aaatttgaca aagacttctt
    19681 tgatttaatc gtaattgatg aagcgcaccg tggttcagct aaggaaaaca gtaactggcg
    19741 taaggtaatt gattatttca gttctgcgac acagattggg atgaccgcta ctcttaaaga
    19801 aaccaagaat gcttccaata cggaatactt tggtgagcca atctatactt atagtttaaa
    19861 acagggaatc gaggatggtt ttttggctcc atatcgtgtt atgagggtta atttagatgt
    19921 ggatgtggat ggttatcgtc cagaaactgg aaaagttgat gctaacggac aattaataga
    19981 agataggtac tacggcagga aagattttga taaaaccatt gtcattgatg atagaacgca
    20041 aagagttgcc aagtttgttt ctgattatat gaagcaaaac aatgcacgat ttgataaaac
    20101 aattgttttt tgtgttgata ttgaccatgc cgagcgaatg cgtgctgcac ttgtaaaaga
    20161 gaatctagac ttagtccaag aagactatcg ttatgtcatg caagtaactg gtgacaacgc
    20221 tgaaggaaaa gctcaactgg ataactttat ggatgtcaat tctaattttc ccgctattgt
    20281 aacaacgtct aaattattaa cgacaggagt taatgctaaa acatgtcgtt tgattgtttt
    20341 agactctaat atccaatcca tgactgaatt taaacaaatt attggtcgtg gcacacgtct
    20401 ttatcctcaa aaggggaaag aattttttac gattattgat tttcgaaatg ttaccaattt
    20461 gtttgctgac cctgattttg atggtgatcc agtgaaggtg ctagaaacag gtgcgaaaac
    20521 agtcagtggt tctacgcccg gtttcgtaga tgaggaaggt gacccagtag aaaaatatat
    20581 cgttacagac aagcaggtta ccattcttaa ttctactgtt caagtattgg atgaaaacgg
    20641 gaaactgatt accgaaagcc tgaccgacta cactcgaaag aatatcttag gtagctacgc
    20701 cactttgaac gattttatca cagtttggca tacggcagat aagaagaagc ttatcttaga
    20761 cgaactttat aaaaaaggag tttatctaga tgctattcga gagtcggagg gaatatcaga
    20821 acaagaaatc gatgattttg atttactcct aaaacttgcc tatggtcaaa aagaattaac
    20881 caaaacggaa cgtatcaata aactcaaaca aagcggatat ttatataaat atagtgagga
    20941 agcgcgtgct gttttggaaa ttttactgaa caaatacatg gataaaggta ttggagaact
    21001 cgaaagcatt gaaacattaa aacttccaga atttcagata tatggtggaa ccttcaaaat
    21061 catcaatact tattttggag ataaaaaacg atatttacaa gcaattaaag aattggagca
    21121 agagctattt acagtagctt aatgaaagga aagtatgtca attacatcat ttgtaaaaag
    21181 aattcaagat atcactcgaa acgatgctgg tgttaatggt gatgctcaac gtattgagca
    21241 aatgtcttgg ttattattct taaaaattta tgatagccgt gaaatggttt gggaattaga
    21301 agaagacgag tatgagtcaa ttatcccaga ggaattaaaa tggcgaaatt gggctcatgc
    21361 tcaaaatggg gaacgggtat tgacaggcga tgaattactt gattttgtca ataacaagtt
    21421 attcaaagag ttgaaagagc ttgaaataac ttcaaatatg cctattcgaa aaacgattgt
    21481 taaatcagct tttgaagatg cgaacaacta tatgaaaaat ggcgtcttgt tacgccaagt
    21541 catcaatgtt attgatgaag ttgatttcaa tagccctgaa gatcgtcatt cgtttaatga
    21601 tatttacgaa aaaattctta aagatattca aaatgctggg aactcaggag aattttatac
    21661 gccacgtgca gcgactgatt ttattgccga agttcttgac ccaaaacttg gagaatcaat
    21721 ggcagacctt gcttgcggaa caggaggctt cttgacttcg actctgaacc gtttaagtag
    21781 tcaacgtaaa actagtgaag ataccaaaaa atataataca gctgtttttg gtattgaaaa
    21841 gaaagcattt cctcatcttt tagcagttac aaatctgttt cttcacgaaa ttgatgaccc
    21901 taaaattgtt catggaaata ctttggagaa aaatgttcgt gaatatacgg atgatgaaaa
    21961 atttgacatt attatgatga atccaccttt tggagggtca gaattagaaa caataaaaaa
    22021 taactttcca gcagaattac ggagttctga aacagctgat ttatttatgg ctgtcattat
    22081 gtatcgtttg aaagaaaatg gtcgtgttgg agttatttta cctgatggtt ttctatttgg
    22141 tgaaggtgta aaaactcgct tgaaacaaaa actggtagat gagttcaact tgcatacgat
    22201 tattaggttg cctcatagtg tctttgcacc gtatacagga atccatacga acattctttt
    22261 ctttgataaa acaaagaaaa cagaagaaac ttggttttat cgtttagata tgccagatgg
    22321 ttataaaaat ttctcgaaaa ctaagccgat gaagtcagaa cacttcaatc ctgttcgtga
    22381 ctggtgggaa aatcgtgaag agattctgga aggtaagttc tacaaatcta aatcatttac
    22441 acctagtgaa ttggctgagt tgaattataa tttagaccag tgtgactttc caaaagagga
    22501 agaggaaatc ttaaatccct ttgagttgat tcagaattat caagcggaaa gagcaacttt
    22561 aaatcataag attgataatg tattagctga tattttgcag ttgttggagg acaaataatg
    22621 acaccagaac aacttaaagc aagtattctc caaagagcga tggaagggaa attagtgccg
    22681 caaaatccca atgacgaacc tgcaagtgaa ttattaaaga gaattaaagc tgaaaaagaa
    22741 aaacttatca gtgaaggaaa aatcaaacga gataaaaagg aaactgagat atttcgtggt
    22801 gatgatggga aacattatgg gaagtttgct gatggaagca ctcaagaaat tgatgttcct
    22861 tatgatattc ctgatacttg ggagtgggtg aggttttcta cattggttga aattgtcaga
    22921 ggtggctctc cacgaccaat caaagattat cttacttctg aagtagatgg aataaattgg
    22981 ataaaaatag gtgatactga aaagggtgaa aagtatataa ataatgttaa agaaaaaatc
    23041 aaaaaatcag ggcttaacaa aactagattt gtaaaaaaag gtacattttt gttaactaat
    23101 tctatgagtt ttggtagacc ttatattttg aatgttgatg gtgcaataca cgatggatgg
    23161 ttggctattt cgaactatga aaactcatta aataaagatt acctattcta tattctttca
    23221 tcaaatgtag tttattctca atttctatct ctaattagtg gagctgttgt gaaaaacttg
    23281 aatagtgata aagttgcttc tattcttatc
//
LOCUS       DAVFER010000032        22887 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1105170250
            SAMEA2167659-rid19724873.denovo.032, whole genome shotgun sequence.
ACCESSION   DAVFER010000032 DAVFER010000000
VERSION     DAVFER010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2167659
            Sequence Read Archive: ERR388902
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 22887)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22887)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928716.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928716.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 04:07:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,118
            CDSs (total)                      :: 2,073
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 120
            CDSs (without protein)            :: 120
            Pseudo Genes (ambiguous residues) :: 0 of 120
            Pseudo Genes (frameshifted)       :: 67 of 120
            Pseudo Genes (incomplete)         :: 47 of 120
            Pseudo Genes (internal stop)      :: 34 of 120
            Pseudo Genes (multiple problems)  :: 23 of 120
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22887
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2167659-rid19724873.denovo.032"
                     /strain="1105170250"
                     /db_xref="taxon:1313"
     gene            complement(330..1178)
                     /gene="dprA"
                     /locus_tag="VU534_001375"
     CDS             complement(330..1178)
                     /gene="dprA"
                     /locus_tag="VU534_001375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-protecting protein DprA"
                     /protein_id="HEU1513953.1"
                     /translation="MKITNYEIYKLKKSGLTNQQILKVLEYGENVDQELLLGDIADIS
                     GCRNPAVFMERYFQIDDAHLSKEFQKFPSFSILDDCYPWDLSEIYDAPVLLFYKGNLD
                     LLKFPKVAVVGSRACSKQGAKSVEKVIQGLENELVIVSGLAKGIDTAAHMAALQNGGK
                     TIAVIGTGLDVFYPKANKRLQDYIGNDHLVLSEYGPGEQPLKFHFPARNRIIAGLCRG
                     VIVAEAKMRSGSLITCERAMEEGRDVFAIPGSILDGLSDGCHHLIQEGAKLVTSGQDV
                     LAEFEF"
     gene            complement(1274..1963)
                     /locus_tag="VU534_001376"
     CDS             complement(1274..1963)
                     /locus_tag="VU534_001376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NTP transferase domain-containing protein"
                     /protein_id="HEU1513954.1"
                     /translation="MKAIILAAGLGTRLRPMTENTPKALVQVNQKPLIEYQIEFLKEK
                     GINDIIIIVGYLKEQFDYLKEKYGVRLVFNDKYADYNNFYSLYLVKEELANSYVIDAD
                     NYLFKNMFRNDLTRSTYFSVYREDCTNEWFLVYGDDYKVQDIIVDSKAGRILSGVSFW
                     DAPTAEKIVSFIDKAYVSGEFVDLYWDNMVKDNIKELDVYVEELEGNSIYEIDSVQDY
                     RKLEEILKNEN"
     gene            complement(1975..2853)
                     /locus_tag="VU534_001377"
     CDS             complement(1975..2853)
                     /locus_tag="VU534_001377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HEU1513955.1"
                     /translation="MKSKNGVPFGLLSGIFWGLGLTVSAYIFSIFTDLSPFVVAATHD
                     FLSIFILLAFLLVKEGKVRLSIFLNIRNVSVIIGALLAGPIGMQANLYAVKYIGSSLA
                     SSVSAIYPAISVLLAFFFLKHKISKNTVFGIVLIIGGIIAQTYKVEQVNSFYIGILCA
                     LVCAIAWGSESVLSSFAMESELSEIEALLIRQVTSFLSYLVIVLFSHQSFTAVANGQL
                     LGLMIVFAAFDMISYLAYYIAINRLQPAKATGLNVSYVVWTVLFAVVFLGAPLDMLTI
                     MTSLVVIAGVYIIIKE"
     gene            complement(2843..3712)
                     /gene="licA"
                     /locus_tag="VU534_001378"
     CDS             complement(2843..3712)
                     /gene="licA"
                     /locus_tag="VU534_001378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline kinase LicA"
                     /protein_id="HEU1513956.1"
                     /translation="MEKIIKEKISSLLSQEEEVLSVEQLGGMTNQNYLAKTTNKQYIV
                     KFFGKGTEKLINRQDEKYNLELLKDLGLDVKNYLFDIEAGIKVNEYIESAITLDSTSI
                     KTKFDKITPILQTIHTSAKELRGEFAPFEEIKKYESLIEEQIPYANYESVRNAVFSLE
                     KRLADLGVDRKSCHIDLVPENFIESPQGRLYLIDWEYSSMNDPMWDLAALFLESEFTS
                     QEEETFLSHYESDQTPVSHEKIAIYKILQDTIWSLWTVYKEEQGEDFGDYGVNRYQRA
                     IKGLASYGGSDEK"
     gene            complement(3729..4751)
                     /locus_tag="VU534_001379"
     CDS             complement(3729..4751)
                     /locus_tag="VU534_001379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HEU1513957.1"
                     /translation="MINQIYQLTKPKFINVKYQEEAIDQENHILIRPNYMAVCHADQR
                     YYQGKRDPKILNKKLPMAMIHESCGTVISDPTGTYEVGQKVVMIPNQSPMQSDEEFYE
                     NYMTGTHFLSSGFDGFMREFVSLPKDRVVAYDAIEDTVAAITEFVSVGMHAMNRLLTL
                     AHSKRERIAVIGDGSLAFVVANIINYTLPEAEIVVIGRHWEKLELFSFAKECYITDNI
                     PEDLAFDHAFECCGGDGTGPAINDLIRYIRPQGTILMMGVSEYKVNLNTRDALEKGLI
                     LVGSSRSGRIDFENAIQMMEVKKFANRLKNILYLEEPVREIKDIHRVFATDLNTAFKT
                     VFKWEV"
     gene            complement(4756..5463)
                     /locus_tag="VU534_001380"
     CDS             complement(4756..5463)
                     /locus_tag="VU534_001380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-C-methyl-D-erythritol 4-phosphate
                     cytidylyltransferase"
                     /protein_id="HEU1513958.1"
                     /translation="MIYAGILAGGTGTRMGISNLPKQFLELGDRPILIHTIEKFVLEP
                     SIEKIVVGVHGDWVSHAEDLVDKYLPLYKERIIITKGGADRNTSIKNIIEAIDAYRPL
                     TPEDIVVTHDSVRPFITLRMIQDNIQLAQNHDAVDTVVEAVDTIVESTNGQFITDIPN
                     RAHLYQGQTPQTFRCKDFMDLYGSLSDEEKEILTDACKIFVIKGKDVALAKGEYSNLK
                     ITTVTDLKIAKSMIEKD"
     gene            5799..7286
                     /gene="tacF"
                     /locus_tag="VU534_001381"
     CDS             5799..7286
                     /gene="tacF"
                     /locus_tag="VU534_001381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV teichoic acid flippase TacF"
                     /protein_id="HEU1513959.1"
                     /translation="MKSIKLNALSYMGIRVLNIIFPILTGTYVARVLDRTDYGYFNSV
                     DTILSFFLPFATYGVYNYGLRAISNVKDNKKDLNRTFSSLFYLCIACTILTTAVYILA
                     YPLFFTDNPIVKKVYLVMGIQLIAQIFSIEWVNEALENYSFLFYKTAFIRILMLVSIF
                     LFVKNEHDIVVYTLVMSLSTLINYLISYFWIKRDIKLVKIHLSDFKPLFLPLTAMLVF
                     ANANMLFTFLDRLFLVKTGIDVNVSYYTIAQRIVTVIAGVVTGAIGVSVPRLSYYLGK
                     GDKEAYVSLVNRGSRIFNFFIIPLSFGLMVLGPNAILLYGSEKYIGGGILTSLFAFRT
                     IILALDTILGSQILFTNGYEKRITVYTVFAGLLNLGLNSLLFFNHIVAPEYYLLTTML
                     SETSLLVFYIIFIHRKQLIHLGHIFSYTVRYSLFSLSFVAIYFLINFVYPVDMVINLP
                     FLINTGLIVLLSAISYISLLVFTKDSIFYEFLNHVLALKNKFKKS"
     gene            7296..8099
                     /locus_tag="VU534_001382"
     CDS             7296..8099
                     /locus_tag="VU534_001382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HEU1513960.1"
                     /translation="MKQLTVEDAKQIELEILDYIDTLCKKHNINYIINYGTLIGAVRH
                     EGFIPWDDDIDLSMPREDYQRFINIFQKEKSKYKLLSLETDKNYFNNFIKITDSTTKI
                     IDTRNTKTYESGIFIDIFPIDRFDDPKVIDTCYKLESFKLLSFSKHKNIVYKDSLLKD
                     WIRTAFWLLLRPVSPRYFANKIEKEIQKYSRENGQYMAFIPSKFKEKEVFPSGTFDKT
                     IDLPFENLSLPAPEKFDTILTQFYGDYMTLPPEEKRFYSHEFHAYKLED"
     gene            8101..8910
                     /locus_tag="VU534_001383"
     CDS             8101..8910
                     /locus_tag="VU534_001383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001199643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HEU1513961.1"
                     /translation="MQYLEKKEIKEIQLALLDYIDETCKKHDIPYFLSYGTMLGAIRH
                     KGMIPWDDDIDISLYREDYERLLKIIEEENHPRYKVLSYDTSSWYFHNFASILDTSTV
                     IEDHVKYKRHDTSLFIDVFPIDRFTDLSIVDKSYKYVALRQLAYIKKSRAVHGDSKLK
                     DFLRLCSWYALRFVNPRYFYKKIDQLVKNAVTNTPQYEGGVGIGKEGMKEIFPVDTFK
                     ELILTEFEGRMLPVPKKYDQFLTQMYGDYMTPPSKEMQEWYSHSIKAYRKN"
     gene            complement(9185..12361)
                     /gene="carB"
                     /locus_tag="VU534_001384"
     CDS             complement(9185..12361)
                     /gene="carB"
                     /locus_tag="VU534_001384"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HEU1513962.1"
                     /translation="MPKRTDIQKIMVIGSGPIIIGQAAEFDYAGTQACLSLKEEGYEV
                     VLVNSNPATIMTDKEIADKVYIEPITLEFVTRILRKEGPDALLPTLGGQTGLNMAMEL
                     SKNGILDELGVELLGTKLSAIDQAEDRDLFKQLMEELEQPIPESEIVNTVEEAVAFAA
                     TIGYPVIVRPAFTLGGTGGGMCANEKELREITENGLKLSPVTQCLIERSIAGFKEIEY
                     EVMRDSADNALVVCNMENFDPVGIHTGDSIVFAPAQTMSDYENQMLRDASLSIIRALK
                     IEGGCNVQLALDPNSFKYYVIEVNPRVSRSSALASKATGYPIAKLAAKIAVGLTLDEV
                     INPVTGSTYAMFEPALDYVVAKIPRFPFDKFEKGERRLGTQMKATGEVMAIGRNIEES
                     LLKACRSLEIGVHHNEIPELAAVSDDALIEKVVKAQDDRLFYVSEAIRRGYTPEEIAE
                     LTKIDIFYLDKLLHIFEIEQELGAHPQDLEVLKTAKLNGFSDRKIAELWGTTDDKVRQ
                     LRLENKIVPVYKMVDTCAAEFDSETPYFYSTYGWENESIRSDKESVLVLGSGPIRIGQ
                     GVEFDYATVHSVKAIQAAGYEAIIMNSNPETVSTDFSVSDKLYFEPLTFEDVMNVIDL
                     EQPKGVIVQFGGQTAINLAEPLAKAGVTILGTQVADLDRAEDRDLFEQALKELDIPQP
                     PGQTATNEEEAALAARKIGFPVLVRPSYVLGGRAMEIVENEEDLRSYMRTAVKASPDH
                     PVLVDSYIVGQECEVDAILDGKNVLIPGIMEHIERAGVHSGDSMAVYPPQTLSQKVQE
                     TIADYTKRLAIGLHCLGMMNIQFVIKDEKVYVIEVNPRASRTVPFLSKVTNIPMAQVA
                     TKLILGQSLSELGYQNGLYPESTRVHIKAPVFSFTKLAKVDSLLGPEMKSTGEVMGSD
                     ATLEKALYKAFEASYLHLPTFGNVVFTIADDAKEEALNLARRFQNIGYGILATEGTAA
                     FFASHGLQAQPVGKIGDDDKDIPSFVRKGRIQAIINTVGTKRTADEDGEQIRRSAIEH
                     GVPLFTALDTANAMLKVLESRSFVTEAI"
     gene            complement(12674..13753)
                     /gene="carA"
                     /locus_tag="VU534_001385"
     CDS             complement(12674..13753)
                     /gene="carA"
                     /locus_tag="VU534_001385"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HEU1513963.1"
                     /translation="MTKRILVLEDGTVFEGKAFGADIDVTGEIVFNTGMTGYQESITD
                     QSYNGQILTFTYPLVGNYGINRDDYESIIPTCKGVVVFEEARRASNWRNQMTLDEFLK
                     AKKIPGISGIDTRALTKIIRKHGTMRATLTHVGDSMDHVTDQLQATVLPTDNIKQVST
                     KTSYPAPGVGLSVVLVDFGLKHSILRELSKRNCNVTVVPYSTTAEEILHLNPDGVMLS
                     NGPGNPEDVPQALDMIRGVQGKIPIFGICMGHQLFAMANGAKTYKMKFGHRGFNHAVR
                     EIATGRVDFTSQNHGYAVSREDLPEHLIITHEEINDKSVEGVRHRYQPAFSVQYHPDA
                     APGPHDASYLFDEFIEMMEVFKQSN"
     gene            complement(13803..14726)
                     /locus_tag="VU534_001386"
     CDS             complement(13803..14726)
                     /locus_tag="VU534_001386"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001293822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HEU1513964.1"
                     /translation="MSENQQALNHVVSMEDLTVDQVMKLIKRGIEFKNGAQLPYEDHP
                     IVSNLFFEDSTRTHKSFEVAEIKLGLERLDFDVKTSSVNKGETLYDTILTLSALGVDV
                     CVIRHPEVDYYRELIASPTITTSIINGGDGSGQHPSQSLLDLMTIYEEFGHFEGLKVA
                     IAGDLDHSRVAKSNMQILKRLGAELFFAGPEEWRSQEFADYGQFVTIDEIIDQVDVMM
                     FLRVQHERHDSGAVFSKEDYHAQHGLTQERYDRLKETAILMHPAPINRDVEIADHLVE
                     APKSRIVQQMTNGVFVRMAILESVLASRNAN"
     gene            complement(14745..15266)
                     /gene="pyrR"
                     /locus_tag="VU534_001387"
     CDS             complement(14745..15266)
                     /gene="pyrR"
                     /locus_tag="VU534_001387"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HEU1513965.1"
                     /translation="MKTKEVVDELTVKRAITRITYEIIERNKDLNKIVLAGIKTRGVF
                     IAHRIQERLKQLENLSVPVVELDTKPFRDDVKSGEDTSLVSVDVTDREVILVDDVLYT
                     GRTIRAAIDNIVGHGRPARVSLAVLVDRGHRELPIRPDYVGKNIPTSRSEEIIVEMTE
                     LDDQDRVLITEEA"
     gene            complement(15477..16106)
                     /gene="nth"
                     /locus_tag="VU534_001388"
     CDS             complement(15477..16106)
                     /gene="nth"
                     /locus_tag="VU534_001388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000244461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HEU1513966.1"
                     /translation="MVLSKKRARKVLEEIIALFPDAKPSLDFTNHFELLVAVMLSAQT
                     TDAAVNKATPGLFVAFPTPQAMSVATESEIASHISRLGLYRNKAKFLKKCAQQLLDDF
                     DGQVPQTREELESLAGVGRKTANVVMSVGFGIPAFAVDTHVERICKHHDIVKKSATPL
                     EVEKRVMDILPPEQWLAAHQAMIYFGRAICHPKNPECDQYPQLYDFSNL"
     gene            complement(16106..16648)
                     /locus_tag="VU534_001389"
     CDS             complement(16106..16648)
                     /locus_tag="VU534_001389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HEU1513967.1"
                     /translation="MKLNIQEIRKQSEGLNFEQTLDLVDDLRARNQEILDVKDILAVG
                     KVQYEDRMYFLDYQLSYTIVLASSRSMEPVELVESYPVTEVFMEGATNQLDQEVLDDD
                     LVLPIENGELDLAESVSDNILLNIPIKVLTAEEEAGQGFISGNDWQIMTEEEYQAQKA
                     VKKEENSPFAGLQGLFDGDE"
     gene            16818..17135
                     /locus_tag="VU534_001390"
     CDS             16818..17135
                     /locus_tag="VU534_001390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000389556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase BlpT"
                     /protein_id="HEU1513968.1"
                     /translation="MEDKKLIQLLSKLNKSYQNCKQGTADDIRLQELLNTTMQELKKT
                     EQLNNSILIDLEKFYQPTSLLIGLGSLKLNDQARTAWRNYDKFHYDHVKHVLSLYGPV
                     FEF"
     gene            17374..18933
                     /locus_tag="VU534_001391"
     CDS             17374..18933
                     /locus_tag="VU534_001391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEU1513969.1"
                     /translation="MHYEHSRKGNHMIKINHLTITQNKDLRDLVSDLTMTIQDGEKVA
                     IIGEEGNGKSTLLKILMGEALSDFTIKGNIQSDYQSLAYIPQKVPEDLKKKTLHDYFF
                     LDSIDLDYSILYRLAEELHFDSNRFASDQEIGNLSGGEALKIQLIHELAKPFEILFLD
                     EPSNDLDLETVDWLKGQIQKTRQTVIFISHDEDFLSETADTIVHLRLVKHRKEAETLV
                     EHLDYDSYSEQRKANFAKQSQQAANNQRAYDKTMEKHRRVKQNVETALRATKDSTAGR
                     LLAKKMKTVLSQEKRYEKAAQSMTQKPLEEEQIQLFFSDIQPLPASKVLVQLEKENLS
                     IDDRVLVQKLQLTVRGQEKIGIIGPNGVGKSTLLAKLQRLLNDKREISLGFMPQDYHK
                     KLQLDLSPIAYLSKTGEKEELQKIQSHLASLNFSYPEMQHQIRSLSGGQQGKLLLLDL
                     VLRKPNFLLLDEPTRNFSPTSQPQIRKLFATYPGGLITVSHDRRFLKEVCSIIYRMTE
                     HGLKLVNLEDL"
     gene            complement(18977..19876)
                     /gene="htpX"
                     /locus_tag="VU534_001392"
     CDS             complement(18977..19876)
                     /gene="htpX"
                     /locus_tag="VU534_001392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metalloprotease HtpX"
                     /protein_id="HEU1513970.1"
                     /translation="MLFDQIASNKRKTWILLLVFFLLLALVGYAVGYLFIRSGLGGLV
                     IALIIGFIYALSMIFQSTEIVMSMNGAREVDEQTAPDLYHVVEDMALVAQIPMPRVFI
                     IDDPALNAFATGSNPQNAAVAATSGLLAIMNREELEAVMGHEVSHIRNYDIRISTIAV
                     ALASAITMLSSMAGRMMWWGGAGRRRSDDDRDGNGLEIIMLVVSLLAIVLAPLAATLV
                     QLAISRQREFLADASSVELTRNPQGMINALDKLDNSKPMSRHVDDASSALYINDPKKG
                     GGFQKLFYTHPPISERIERLKQM"
     gene            complement(19878..20438)
                     /locus_tag="VU534_001393"
     CDS             complement(19878..20438)
                     /locus_tag="VU534_001393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LemA family protein"
                     /protein_id="HEU1513971.1"
                     /translation="MTWIILGVIALIVIFVIVSYNGLVKNRMQTKEAWSQIDVQLKRR
                     NDLLPNLIETVKGYAKYEGSTLEKVAELRNQVAAATSPAEAMKASDALTRQVSGIFAV
                     AESYPDLKASANFVKLQEELTNTENKISYSRQLYNSVVSNYNVKLETFPSNIIAGMFG
                     FKAADFLQTPEEEKSVPKVDFSGLGD"
     gene            20532..21245
                     /gene="rsmG"
                     /locus_tag="VU534_001394"
     CDS             20532..21245
                     /gene="rsmG"
                     /locus_tag="VU534_001394"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HEU1513972.1"
                     /translation="MKPKTFYNLLAEQNLPLSDQQKEQFERYFELLVEWNEKINLTAI
                     TDKEEVYLKHFYDSIAPILQGLIPNETIKLLDIGAGAGFPSLPMKILYPELDVTIIDS
                     LNKRINFLQLLAQELDLNGVHFYHGRAEDFAQDKNFRAQYDFVTARAVARMQVLSELT
                     IPYLKVGGKLLALKASNAPEELLEAKNALNLLFSKVEDNLSYALPNRDPRYITVVEKK
                     KETPNKYPRKAGMPNKRPL"
     gene            21499..22782
                     /locus_tag="VU534_001395"
     CDS             21499..22782
                     /locus_tag="VU534_001395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007554578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil permease"
                     /protein_id="HEU1513973.1"
                     /translation="MKQESTVDLLLDVDQRPSAGKGILLSFQHVFAMFGATILVPLIL
                     GMPVSVALFASGVGTLIYMIATGFKVPVYLGSSFAFITAMSLAMKEMGGDVSAAQTGV
                     ILTGLVYVLVATSIRFVGTKWIDKLLPPIIIGPMIIVIGLGLAGSAVTNAGLVADGNW
                     KNALVAVVTFLIAAFINTKGKGFLRIIPFLFAIIGGYLFALTLGLVDFTPVLKANWFE
                     IPGFYLPFSTGGAFKEYNLYFGPEAIAILPIAIVTISEHIGDHTVLGQICGRQFLKEP
                     GLHRTLLGDGIATSVSAFLGGPANTTYGENTGVIGMTRIASVSVIRNAAFIAIALSFL
                     GKFTALISTIPNAVLGGMSILLYGVIASNGLKVLIKERVDFAQMRNLIIASAMLVLGL
                     GGAILKLGPVTLSGTALSAMTGIILNLILPYENKD"
BASE COUNT         6900 a         4859 c         4239 g         6889 t
ORIGIN      
        1 cactatactt tcccttatac tcaatgaaaa tcaaagcgca aactaggaag ctagccacag
       61 gttgctcaaa gcactgcttt gaggttgtag ataagactga cgaagtcagc tcaaaatact
      121 gttttgaggt tgcagatgga agctgacgta gtttgaagag attttcgaag agtattatat
      181 gagaaaaatc ctctactcta ctaatccact tagaaaaaac gcatattatc aagtgttaaa
      241 aacttgctaa tatgcgtttt attatggaaa tgttgggttc attttctctt aaaattgatt
      301 ttttcttaga attctagctt aggtcatttt taaaattcaa attccgcaag aacatcttgc
      361 ccactggtga ccaattttgc tccttcttga atcaaatgat ggcaaccgtc tgatagtcca
      421 tctaaaatgc taccaggaat agcaaagaca tcgcgtcctt cttccattgc tcgctcacac
      481 gtaatgagac tacctgaacg catcttagcc tctgctacaa tcacaccacg acaaagtcca
      541 gcaatgatgc gattacgggc aggaaaatga aatttcagag gttgttcacc aggtccatat
      601 tcacttagaa ccagatggtc attgccgatg tagtcttgca agcgtttatt ggctttagga
      661 taaaacacat ccagtcctgt tccaatcact gcaatggttt ttccgccatt ctgaagagct
      721 gccatatgag ctgctgtgtc aatgcccttg gccagaccac tgacaataac cagttcattt
      781 tccaagcctt gaatgacttt ttcaactgac ttagctccct gtttgctaca agcacgactg
      841 cccacgaccg ctaccttcgg gaatttcagg aggtcaagat ttcccttgta aaataaaagt
      901 acaggcgcat catatatttc actcaaatcc caaggataac agtcatctaa aatagagaaa
      961 gatggaaatt tttgaaactc tttcgacaaa tgcgcatcgt ctatctgaaa ataacgttcc
     1021 ataaaaacgg ctggattacg gcaacctgag atatctgcaa tatcacccaa caaaagctcc
     1081 tgatcaacat tttcaccgta ttctagcact ttcaaaatct gttgattggt caaacctgat
     1141 ttttttaact tatagatttc atagtttgtg attttcataa ataactccat ttctttttct
     1201 actcatctat ctattcgtaa aagttcgtaa aaaatcaaaa aacatccgac tattttgtca
     1261 gatgttggaa tctttaattt tcgtttttaa gaatttcttc taatttacga tagtcttgga
     1321 cactatcgat ctcataaatg ctattgcctt ctaattcttc aacatagaca tctagctctt
     1381 tgatattatc cttaaccata ttgtcccaat agagatcaac aaattcacca cttacataag
     1441 ccttgtcgat aaagctgaca atcttttctg cagttggagc atcccagaag gatacaccac
     1501 taaggatgcg acctgccttg ctatcaacaa taatgtcttg aaccttgtag tcatctccat
     1561 aaaccaagaa ccattcgttg gtacaatctt cacgataaac actaaaataa gtcgaacgtg
     1621 tcaaatcatt gcggaacata tttttaaaga gataattgtc agcatcaata acatagctgt
     1681 tggccaattc ttcttttaca agatagagag agtaaaagtt attgtagtca gcgtatttat
     1741 cattgaaaac gagacgaaca ccgtatttct ctttcaagta atcgaattgt tctttaagat
     1801 aaccaacaat gatgatgatg tcattgattc ctttttcttt gagaaactca atttggtact
     1861 caatcaaagg tttttgatta acctgaacca aggctttagg ggtattttca gtcataggac
     1921 gcaagcgagt tcccaatccc gctgctaaga taatggcttt cacacgaatc tcctttattc
     1981 tttaataata atataaactc cagcaatgac gacaagtgac gtcataatgg tcagcatatc
     2041 tagcggtgca cccaagaaaa caactgcaaa caagaccgtc catactacat agctcacgtt
     2101 caagcctgta gccttggctg gttgcaagcg attgatagcg atataataag ccaagtagga
     2161 aatcatatca aaggctgcaa aaacaatcat gagacctagc aattgtccat tggctactgc
     2221 agtaaatgac tgatgagaga agagcacaat cacaagatag gacaagaacg aagttacttg
     2281 acggattaag agggcttcga tttcactcaa ttcactttcc atggcaaaag agctaagaac
     2341 actctcactt ccccatgcaa tagcacaaac caaagcacaa agaatcccaa tgtagaaaga
     2401 attaacctgt tcaaccttat aggtctgagc aataatccct ccaataatca agacaatccc
     2461 aaatacagta tttttcgaaa tcttgtgctt caaaaagaag aaagccaata gaactgaaat
     2521 cgcagggtaa atagccgata cagatgaagc taaagaactt ccgatatact taactgcata
     2581 aagattggcc tgcataccga tagggcctgc tagcaaggct ccgatgataa cactgacatt
     2641 gcgaatattt aagaaaattg agaggcgaac tttcccttct tttaccaaga gaaaagctag
     2701 taagataaag atgctcaaaa aatcatgagt tgcagccacc acaaagggtg acaaatctgt
     2761 aaaaatcgaa aagatataag cactaaccgt tagacccaag ccccagaaaa tacctgagag
     2821 aaggccaaaa ggaactccgt ttttactttt catctgaacc tccataagaa gccaaacctt
     2881 taatagctct ttggtaacga ttcacaccat agtcaccaaa atcttcacct tgctcttcct
     2941 tatagacagt ccatagactc caaatagtat cttgtaaaat tttataaata gcaatctttt
     3001 catgagaaac cggtgtttgg tcactctcat agtgagataa gaaagtttct tcctcttggg
     3061 aagtgaattc agactctaaa aagagggcag ccaaatccca cattggatca ttcattgatg
     3121 aatattccca gtcaatcaaa taaagtcgtc cttgaggtga ttcgataaag ttttcaggca
     3181 ccaaatcgat atgacaagat tttctgtcaa cacctaagtc agccagtctt ttctctaagg
     3241 agaagactgc atttctaaca gattcatagt tggcataagg aatttgttct tcaatcaagg
     3301 attcgtattt tttgatttct tcaaaaggag caaattctcc tcttaattcc ttagcagacg
     3361 tatgaatagt ttgtaatatt ggagtaattt tgtcgaactt ggtcttgatt gacgttgaat
     3421 caagcgtaat cgcagattcg atatactcat ttactttgat accagcttca atatcaaaaa
     3481 gataattttt tacatctaag cctaaatcct ttagtagttc aagattgtac ttttcatctt
     3541 gtcgattgat aagcttttct gtccctttac caaagaattt aacaatgtat tgcttatttg
     3601 ttgttttggc caaatagttt tgattggtca ttccacccag ttgttcaaca ctgaggactt
     3661 cctcttcttg actaagtaag gaagaaattt tttctttaat gattttctcc acaattaacc
     3721 tccagtactt atacttccca cttaaacact gttttaaagg ctgtgtttaa atcggttgca
     3781 aagacacgat gaatatcttt aatttctctt acaggttctt ctagataaag gatattttta
     3841 agacgattgg caaatttctt gacttccatc atttggatag cattttcaaa atcaatgcga
     3901 ccagaacgag atgacccaac caaaatcaag cccttttcta aggcatcgcg agtattgaga
     3961 ttgactttat attcgctaac tcccatcatg agaatcgttc cctgaggacg aatgtagcga
     4021 atcaagtcat taatagctgg tccagtacca tcaccaccac aacattcaaa agcatggtca
     4081 aaggccaaat cttcaggaat attatccgta atatagcatt ctttggcaaa tgagaagagt
     4141 tccaactttt cccaatgacg accaataacc acaatctctg cttctggcaa agtatagttg
     4201 ataatattgg caaccacaaa agctaaactt ccatctccaa taacggcgat ccgctcccgc
     4261 ttgctatgag caagagtcaa tagacgattc atagcgtgca tgcccacact gacaaactct
     4321 gtaatggctg caaccgtatc ttcaatagca tcataagcca ccacacgatc tttagggaga
     4381 gaaacaaact ctctcataaa gccatcaaat ccactagaca agaaatgggt ccctgtcatg
     4441 tagttttcat agaattcttc atcactctgc ataggagact gattgggaat catgacaact
     4501 ttttgaccaa cctcgtaggt tccggtcggg tcagaaatga cggttccaca tgactcgtga
     4561 atcattgcca ttggaagctt tttattcaaa atcttgggat cacgttttcc ctgatagtaa
     4621 cgctgatccg catgacagac agccatgtag ttgggacgga taaggatatg attctcttgg
     4681 tcaatagcct cttcctgata tttgacattg ataaacttag gcttagttag ttgataaatt
     4741 tgattaatca ttttactagt ctttctcaat catacttttt gcaatcttca aatctgttac
     4801 ggttgtaatc ttcagatttg agtattcacc tttggccaaa gccacatctt ttcctttgat
     4861 cacaaagatt ttacatgcat ctgtcaagat ttccttctct tcatcagaaa gagatccata
     4921 aaggtccatg aagtccttgc aacggaatgt ttgaggtgtt tgtccttgat aaaggtgagc
     4981 acgatttgga atatctgtaa taaattgacc attggtactt tcaacgatag tatcaaccgc
     5041 ttctaccact gtgtccactg cgtcatgatt ttgggcaagt tggatattgt cctgaatcat
     5101 gcgaagtgta ataaatggac gaacagaatc gtgggtaaca acgatatcct ctggagtaag
     5161 cggacgataa gcatcaatgg cttcaatgat gttcttaata cttgtattgc ggtcagcacc
     5221 accctttgta atgatgatac gttccttata aagaggaaga tatttatcta caagatcttc
     5281 tgcatgagaa acccagtctc catgaacacc aactacaatt ttttcaatac ttggctccaa
     5341 gacaaatttt tcaattgtat gaatcaaaat aggtcgatca cctagctcta aaaattgttt
     5401 tggcaagtta ctgatcccca tgcgtgtgcc agttccaccg gcaagaattc ctgcataaat
     5461 catctatttt ctcctttgtc ttactaaaaa aacttattct ctctattata ccacaatcta
     5521 gtcctatcat aaaagaaata ctggtcctcc ccttctagaa taggagaatt atgcagttct
     5581 attattcaaa gaaactagtc catttctagt aatgactagg aattctgtag caattactaa
     5641 taaatggctg cgaaatttta gagtccttca gaataatata ctttccttaa agaaaactta
     5701 aaacttaaga tttgaaactt caaagtgatt acttgactta ctgcccttca tttcttatta
     5761 gctaacttta tgatataatg aaaaacgagg taaattgaat gaaaagtata aaattaaatg
     5821 ctctatctta catgggaatt cgtgtcttga atattatttt tcccatccta actggaacct
     5881 atgtcgcgcg tgtcttggac cgaactgact atggttactt caactcagtc gacactattt
     5941 tgtcattttt cttgcccttt gcaacttatg gtgtctataa ctacggttta agggctatca
     6001 gtaatgtcaa ggataacaaa aaagatctta acagaacctt ttctagtctt ttttatttgt
     6061 gcatcgcttg tacgattttg accactgctg tctatatcct agcctatcct ctcttcttta
     6121 ctgataatcc aatcgtcaaa aaggtctacc ttgttatggg gattcaactc attgcccaga
     6181 ttttttcaat cgaatgggtc aatgaagctc tggaaaatta cagttttctc ttttacaaaa
     6241 ctgccttcat ccgtatcctg atgctggtct ctattttctt atttgttaaa aatgaacacg
     6301 atattgttgt ctatacactt gtgatgagtt tatcgacgct gattaactac ctgattagtt
     6361 atttttggat taaaagagac atcaaacttg ttaaaattca cctaagtgat tttaaaccac
     6421 tctttctccc tctgacagcc atgttagtct ttgccaatgc caatatgctc ttcacttttt
     6481 tagatcgcct cttcctcgtt aaaacaggga ttgatgtcaa cgttagttac tataccatag
     6541 ctcagcgaat tgtgaccgtt atagctgggg ttgtaacagg tgcaattgga gtgagtgtgc
     6601 ctcgtctcag ttactatctg gggaaaggag acaaagaagc ctatgtttct ctggttaata
     6661 gaggtagtcg aatctttaac ttctttatca ttccactgag ttttggactc atggttttag
     6721 gaccaaatgc catcctactt tacggtagtg aaaaatatat cggaggcggc atcttgacct
     6781 ctctcttcgc ttttcgtacg attatcctgg ccttagatac cattcttggt tcccaaattc
     6841 tctttaccaa tggctatgaa aaacgtatca cagtctatac agtctttgct gggctactca
     6901 atttgggctt gaatagtctc ctttttttca accatatcgt ggctcctgaa tactacttac
     6961 tgacaactat gctatcagag acttctctac ttgttttcta tatcattttc atccatagaa
     7021 aacaactcat ccacttggga catatcttta gctatactgt tcgatactct ctcttttcac
     7081 tttcctttgt agcaatttat ttcctgatta atttcgtgta tcctgtagat atggtcatta
     7141 atttgccatt tttgattaat actggtttga ttgtcttgct atcagctatc tcttatatta
     7201 gtctacttgt cttcacaaaa gatagcattt tctatgaatt tttaaaccat gtcctagcct
     7261 taaaaaataa atttaaaaaa tcataggagt ttaaaatgaa acaactaacc gttgaagatg
     7321 ccaaacaaat tgaattagaa attttggatt atattgatac tctctgtaaa aagcacaata
     7381 tcaactatat tattaactac ggtactctga ttggggcggt tcgacatgag ggctttatcc
     7441 cttgggacga cgatattgat ctgtccatgc ctagagaaga ctaccaacga tttattaaca
     7501 tttttcaaaa ggaaaaaagc aagtataagc tcctatcctt agaaactgat aagaactact
     7561 ttaacaactt tatcaagata accgacagta cgactaaaat tattgatact cgaaatacaa
     7621 aaacctatga gtctggtatc tttatcgata ttttccctat agatcgcttt gatgatccta
     7681 aggtcattga tacttgttat aaactggaaa gcttcaaact gctgtctttc agtaaacata
     7741 aaaatattgt ctataaggat agccttttaa aagattggat acgaacagcc ttctggttac
     7801 tccttcgacc ggtttctcct cgttattttg caaataaaat cgagaaagaa attcaaaaat
     7861 atagtcgtga aaatgggcaa tatatggctt ttatcccttc aaaatttaag gaaaaggaag
     7921 tcttcccaag tggtaccttt gataaaacaa tcgatttacc ctttgagaat ttaagccttc
     7981 ctgcacctga aaaatttgat actattttga cacaatttta tggagattat atgaccctac
     8041 caccagaaga aaaacgcttc tacagtcatg aatttcacgc ttataaattg gaggattagg
     8101 atgcaatatt tagaaaaaaa agaaattaaa gaaattcaac tagccctgct ggactatatt
     8161 gatgagactt gtaagaaaca tgatattcct tattttctca gttatggaac catgcttgga
     8221 gccatccgcc acaaaggtat gattccttgg gatgatgata ttgatatttc cctttatcgt
     8281 gaggattatg agcgtttact gaagattatt gaagaagaaa atcaccctcg ctacaaggtt
     8341 ctttcctacg atacatcttc ttggtacttc cataatttcg catcgatttt ggacacttct
     8401 actgttatag aagaccatgt taagtacaag cgtcatgata ccagcctttt catcgatgtc
     8461 ttcccaattg atcgatttac agacttgagc attgtcgaca agagctataa gtatgtggct
     8521 cttcgtcaac tagcttatat caaaaaatca cgagcagttc acggtgatag caaactaaaa
     8581 gattttctta gattatgtag ctggtacgct ctccgatttg tcaatcctcg ctacttttac
     8641 aagaaaattg atcaactagt caaaaatgct gtaaccaaca ctcctcaata tgaaggagga
     8701 gttgggatcg gtaaggaagg gatgaaagaa atcttcccag ttgatacctt taaagaactg
     8761 attttaactg agtttgaggg ccgtatgttg cctgttccca aaaaatatga ccaattttta
     8821 acccagatgt atggcgatta tatgacacca ccatcaaaag aaatgcaaga gtggtatagt
     8881 catagcatta aagcttatcg caaaaactga ttgaggggga ttatacaaac tactaagata
     8941 gaggttattc aaaaacataa ttttagtaga aaatgaaata catattccca caataaaacg
     9001 catcatatca aggtttttga aaaaccttga tatgatgcgt tttataattt taaagacttt
     9061 tttctatagt agattgaaat aagatgcgaa caaatcaatt agaaaattca aattaattta
     9121 tagaaatatt ttagtattcc tgtgtactgt tctaaattca gtctgctata tcttattttt
     9181 ctatttaaat cgcttctgta acaaagctac gactttcaag taccttaagc atggcattag
     9241 ctgtatctag cgctgtgaag aggggcaccc cgtgttcaat ggctgaacga cgaatttgct
     9301 caccatcttc gtcagcagtt cgttttgttc ctactgtgtt aatgatagct tgaattcttc
     9361 ctttgcgtac aaaacttggg atatccttat cgtcatcacc aatcttacca acaggttggg
     9421 cttgcaagcc atgactagca aagaaggctg ctgtcccttc tgtcgcaagg attccataac
     9481 caatgttttg gaaacgacga gccaagttca aggcttcttc tttggcatca tcagcgatgg
     9541 taaagacgac attaccaaaa gttggcaagt gtagataaga agcttcaaag gctttataga
     9601 gagctttttc caaagtagca tcagaaccca taacttcacc tgttgacttc atttcaggac
     9661 cgagcaagct gtctacctta gctagtttgg taaaggagaa gacaggtgcc ttgatatgaa
     9721 cacgggtgct ttcagggtaa agtccatttt ggtagccaag ttctgataaa ctttgaccaa
     9781 gaatgagttt ggtcgctact tgagccatag gaatattggt taccttagat aggaatggaa
     9841 cagtacggct ggcacgtgga ttgacctcaa taacgtagac tttttcatcc ttgataacaa
     9901 actggatgtt catcattcca aggcagtgaa gaccgattgc taagcgtttg gtgtagtctg
     9961 cgatggtctc ctgaaccttt tgcgacaagg tttgtggtgg gtaaacagcc attgagtcac
    10021 ctgagtggac accagcacgt tcgatatgct ccatgatacc aggaatgagt acatttttac
    10081 catctaaaat ggcatcaact tcgcactctt gcccaacgat ataagagtcg acaagaactg
    10141 ggtggtctgg actagcctta acagcagttc gcatgtaaga acgaaggtct tcttcgtttt
    10201 caacgatttc catggcacgt ccaccaagta cataagatgg gcggacaaga actgggaagc
    10261 caatcttgcg agctgcaaga gctgcttctt cttcattggt agccgtttgt cctggtggct
    10321 gtggaatatc caattctttg agagcttgct cgaagaggtc acggtcttcg gcacgatcta
    10381 ggtcagcaac ctgtgtacca aggatggtca cacctgcttt tgccaatggc tccgcaaggt
    10441 tgatggctgt ttgaccaccg aactgaacga taactccctt tggttgttcc aagtcaatga
    10501 cgttcataac atcttcgaat gtcaatggct caaagtaaag cttatctgat acagagaagt
    10561 ctgttgaaac ggtctctggg tttgagttca tgatgatagc ttcataacca gctgcctgga
    10621 tagccttaac agagtgaacg gttgcgtagt caaactcaac cccttgaccg atacggattg
    10681 gacctgaacc taggacaagt acagattctt tatcagatct gatagattca ttttcccaac
    10741 cataggttga atagaaatat ggcgtttcgg agtcgaactc tgccgcacaa gtgtctacca
    10801 tcttataaac tggaacaatc ttgttttcca agcgaagttg gcgaacttta tcatcagtcg
    10861 ttccccagag ttcagcaatc ttacggtctg aaaaaccatt aagtttggct gttttcaaaa
    10921 cttctaaatc ttgtggatga gcacccaatt cttgctcaat ttcaaagata tgcaagagtt
    10981 tatcaagata gaagatatca atttttgtaa gctctgcaat ttcttcaggt gtgtagccac
    11041 gacgaatggc ttctgatacg tagaagagac ggtcatcttg ggctttgaca accttttcaa
    11101 tcaaggcatc atcagaaact gctgcaagtt caggtatttc attgtggtgc accccaattt
    11161 caagggagcg gcaggccttg agaagagatt cctcgatgtt acgaccgatt gccatgactt
    11221 ctccagtcgc cttcatttgt gtaccgagac ggcgttcacc cttttcaaac ttgtcaaatg
    11281 ggaaacgtgg aatcttagca actacgtagt caagggctgg ttcaaacatg gcataggttg
    11341 aacctgtaac tgggtttata acctcatcca aggtcaaacc tactgcaatc ttggcagcca
    11401 acttagcaat cggatatcct gtcgctttag aagcaagggc tgacgaacgt gatacacgag
    11461 ggtttacttc gataacataa tacttgaagc tgttaggatc aagagctagc tgaacattac
    11521 atccaccttc aatcttgagg gcacgaataa tgctcaagct cgcatcacga agcatttggt
    11581 tttcatagtc tgacatggtt tgcgcagggg caaatacaat ggaatcccct gtgtgaatcc
    11641 caactgggtc aaagttttcc atgttacaaa caaccaaggc attgtcagct gagtcacgca
    11701 tcacttcgta ttcaatttcc ttgaaaccgg caatcgaacg ctcaatcaaa cattgggtaa
    11761 caggtgacaa tttcaaacca ttttcagtga tttcacgcaa ttctttctcg ttggcacaca
    11821 taccaccacc agtaccacca agggtaaagg ctggacgaac gatgactggg tagccaattg
    11881 tcgctgcaaa ggcaactgct tcttctactg tgttaacaat ttcagattct ggaatgggtt
    11941 gttcaagctc ttccatcaat tgtttaaaga ggtcacggtc ctccgcttgg tcaatggcag
    12001 ataatttggt acccagaagt tcaacgccaa gctcgtctag gataccattt ttagataatt
    12061 ccatggccat gttgagacct gtctgaccac cgagtgttgg tagcaaggca tctggacctt
    12121 ccttacgaag aatacgtgtc acaaactcaa gtgtaatcgg ttcaatgtaa accttgtcag
    12181 caatttcctt gtccgtcatg atggttgcag gatttgagtt aaccaaaaca acctcataac
    12241 cttcctcttt caacgacaag caagcctgag tcccagcgta gtcaaactca gcagcctgac
    12301 caataataat cggaccagaa ccaatcacca taattttttg aatatcagta cgtttaggca
    12361 tatataagat attaagggtg tcaagcggac aaagctaaaa taggagttat gacgaagaac
    12421 tgtcagttct aggaataact atctttttag caccgtccgt agcccgtatt cagttcagca
    12481 aatacggagc acccttctcc tttctattcg tcgcctctca gggcgacatt aaataagata
    12541 caaaggacga atagaaagcg attgaatttt aggaaatcaa ggaaggattg acaatccaag
    12601 ttggtttctc tacattctga gctttccgtc cgtgttcagt tacataaatt ctccgacgag
    12661 cttttactcg ttcttagttt gattgtttaa aaacttccat catctcgata aactcgtcaa
    12721 ataggtagct agcgtcgtgt ggcccaggag ctgcatctgg gtggtattga acagagaaag
    12781 caggttggta tctgtggcgc acaccttcca ctgacttgtc attgatttct tcgtgggtaa
    12841 taatcaagtg ctctggcaaa tcctcgcggc tgactgcata accatggttc tggctggtga
    12901 agtctactcg tcctgttgcg atttcacgta ccgcatggtt gaatccacgg tggccaaact
    12961 tcatcttata ggtcttagcc ccgtttgcca ttgcaaagag ttggtgtccc atacaaatac
    13021 caaagattgg aatttttcct tgtacaccgc gaatcatgtc gagtgcttgt ggaacgtctt
    13081 ctgggttacc tggaccattt gacaacataa ctccgtcagg attgagatgg agaatttctt
    13141 cagccgttgt cgaataagga acaactgtca cgttacagtt gcgtttagaa agttcacgta
    13201 ggattgagtg cttgagacca aagtccacta gcaccacgct caaaccaact cctggagctg
    13261 gataagacgt tttagtagaa acctgtttga tattgtctgt cggtaaaact gttgcttgga
    13321 gctggtccgt cacatggtcc atactgtccc caacatgggt caaggttgca cgcatagtac
    13381 catgcttacg gataatcttg gtaagagcac gcgtatcaat tcctgaaatc cctggaattt
    13441 tcttggcttt caaaaattca tccaaggtca tttggttgcg ccagttgcta gctctacgcg
    13501 cttcttcaaa aacaacgact cccttacaag ttggaataat ggattcataa tcatcacgat
    13561 taataccata atttcctacc aaaggataag taaaggtcaa gatttgtcca ttataagact
    13621 ggtctgtaat ggattcttgg tagccggtca tccctgtatt aaagacgatt tcgcctgtta
    13681 catcaatatc tgctccgaag gccttgcctt caaaaactgt gccatcttct aatactagaa
    13741 ttctttttgt catattttca cctctcgtgg acgctcactg gcgtctttta acgtcttgtg
    13801 ttttagttgg cgtttctact cgctagtacg gattctaaga ttgccattcg aacaaagaca
    13861 ccattggtca tttgttggac aatccgtgat tttggtgctt caaccaagtg gtctgctatt
    13921 tctacatcac gattgattgg agctgggtgc atgaggattg ctgtttcttt caaacgatcg
    13981 taacgttctt gagtcaagcc atgttgggca tggtagtctt cttttgaaaa tacagctcca
    14041 ctatcatggc gttcgtgttg cacacggaga aacatcatga catcaacctg atcaatgatt
    14101 tcatcaatgg ttacaaactg tccatagtct gcaaactctt gacttctcca ttcctcaggt
    14161 ccagcgaaaa agagttcagc tcccaagcgt ttcaaaatct gcatattgga tttggcaacg
    14221 cgtgagtggt ccaagtcacc tgcaatagca actttaagac cctcaaagtg gccaaattcc
    14281 tcataaatgg tcatcaaatc aagcaagctc tggctagggt gttggcccga accatctcca
    14341 ccattgatga tggaagtcgt aatcgttgga ctagcaatca attctctata gtagtcgacc
    14401 tctggatggc gaatcacaca gacatccact cctaaagcag acagagtcaa aatggtgtca
    14461 taaagtgtct cacccttatt aaccgagcta gtcttcacat caaagtcaag tcgttccaat
    14521 ccaagtttaa tctctgcgac ttcaaaggac ttatgtgtcc gtgtagaatc ctcaaagaag
    14581 agattggaaa caatcggatg gtcttcatag ggaagctggg ctccattttt aaactcaatt
    14641 cctcgcttga tcaatttcat tacttgatcg acagtgaggt cttccatgga caccacatgg
    14701 ttcaatgctt gttgattttc tgacatggct actcctttaa ctttctaagc ttcttcagta
    14761 atcagaactc tgtcttggtc atcaagttct gtcatctcta cgatgatttc ttcagaacga
    14821 ctggttggga tattttttcc aacgtaatct ggacggattg gcaattctct atgtccacga
    14881 tcgactagaa ctgctaaact cacacgcgca ggacgaccat gaccgacaat attatcaata
    14941 gcagcacgga tggtacgacc tgtatagagc acatcatcca ccaagataac ttcgcggtct
    15001 gtcacatcga cagaaaccaa agaagtatct tctccacttt taacatcatc acggaaaggt
    15061 ttagtatcca attccacaac aggaactgaa agattttcta actgcttcaa acgttcttgg
    15121 attcggtggg caataaagac accacgagtt ttaataccag ccaagacgat cttattcaaa
    15181 tctttgttgc gttcgataat ctcataagta atacgcgtaa tcgctcgttt gacggtcaat
    15241 tcgtctacaa cttcttttgt tttcatgaca aacctccaaa aagaaaagtc tccttaaaca
    15301 aggagacttg aaatttatag ccaagcgagc cctactgcac acagtataga cttcaccctt
    15361 ctactttatc gcgctccttg cctgcctcac gggacaggtt taaaggaata tttagttatc
    15421 atttactata gcacaaagca tgcttaaaat caagcaaaaa gtttcaatgt agcatcttac
    15481 aaattgctaa aatcatataa ttgtgggtac tggtcacact ctggattttt tggatggcaa
    15541 atggctcttc caaaataaat catggcctga tgggcagcta accactgctc aggcggcaag
    15601 atatccatga cccgcttttc cacctcaagt ggcgtcgctg attttttgac aatatcgtgg
    15661 tgtttgcaaa tacgctccac atgagtatcc actgcaaagg ctggaattcc aaatcctaca
    15721 ctcatgacaa cattggctgt cttgcgacca acacctgcca aactctccaa ttcttcacgt
    15781 gtctgaggga cttgaccatc aaaatcgtct agtaactgtt gggcacattt tttaaggaat
    15841 ttagctttat tccgatacaa tcccaagcga gaaatatgtg aagcaatctc actctctgtc
    15901 gctacagaca tagcttgggg tgttggaaag gcaacaaaga gacctggtgt ggccttattt
    15961 accgctgcat ctgtcgtctg ggctgataac atgaccgcaa ccaggagttc aaaatgattg
    16021 gtaaaatcaa gactaggctt ggcatctggg aagagggcaa tgatttcttc tagcaccttt
    16081 cgtgctcgtt tttttgacaa gaccattatt catctccgtc aaatagtcct tgtaagccag
    16141 caaaaggact gttttcttct ttctttactg ctttttgagc ttggtattct tcctctgtca
    16201 tgatttgcca gtcatttcct gagataaatc cttgaccagc ttcttcttca gccgtcaaga
    16261 ccttgatagg aatgtttagc aggatattgt ctgatacact ctcagcaagg tcaagctccc
    16321 cattttcgat gggcaagacc aagtcatcat ctaaaacttc ttgatctagc tggttagttg
    16381 cgccttccat gaaaacttcc gtgactggat aagattcaac taactcaact ggctccatac
    16441 tgcgactcga agcaagaaca atggtataag atagttgata atctaagaaa tacatacggt
    16501 cttcatattg tactttccca actgcaagga tatcttttac atctaaaatt tcttgattac
    16561 gtgcacgcag gtcatcaact aaatctaacg tttgttcaaa gttcaaacct tcagactgct
    16621 tacgaatttc ttgaatattt aatttcatac ttcctccata aagatttact ctcttgatta
    16681 taccatgaaa aggctacaaa tcagcacacc aaactttgta attaaaattc aaaattttaa
    16741 catatttact atgatagttt tattttttag tgctatacta tagggaaaga gtacatcaga
    16801 tcaaggagga tgctcacatg gaagacaaga aactcattca actcctatcc aagttaaata
    16861 aaagctacca aaactgtaaa cagggtacgg cagatgatat tcgactacaa gagctgctaa
    16921 acactactat gcaagagctc aaaaaaacgg aacagttgaa caacagtatc ttaattgatc
    16981 ttgagaaatt ttaccaacct accagtcttc tgattggact gggtagccta aaactaaacg
    17041 atcaagcacg cactgcttgg cgaaactatg ataaattcca ttacgatcat gtcaaacacg
    17101 tactaagtct ctatggacct gtttttgaat tttagagcat agaatttcca gttttctgtt
    17161 gacaaaattt ccttaaaggt ataatataaa gatactaata ctcggaggta agggagacat
    17221 gaacaactaa gtctatcaaa taaagaacct ttatttagta gatcttgttt ttgtctcttt
    17281 ttgtgtgctc ttttatgctc tttttctggc atgttaatag agtttttttg acatagactt
    17341 tgggctctac taggtaaagt agagcttttt gttatgcact atgaacattc tagaaaggga
    17401 aatcatatga taaaaatcaa tcatctaacc atcacacaaa acaaagattt acgagatctt
    17461 gtatctgacc taaccatgac catccaagac ggggaaaagg ttgctattat tggtgaagaa
    17521 ggaaatggca aatcaacctt acttaaaatt ttaatggggg aagctttgtc tgatttcact
    17581 atcaagggaa acatccaatc tgactatcag tcactggcct acattcctca aaaagtccct
    17641 gaggacctaa aaaagaaaac tttacacgac tacttctttt tagattctat tgatttagac
    17701 tacagtatcc tctatcgttt ggcggaggaa ttgcattttg atagcaatcg tttcgcaagt
    17761 gaccaagaga ttggcaatct atcagggggc gaagctttga aaattcagct tatccatgag
    17821 ttagccaaac cctttgagat tctattttta gatgaacctt caaatgacct agaccttgag
    17881 acagttgatt ggctaaaagg ccagattcaa aagaccaggc aaaccgttat tttcatttcc
    17941 catgatgaag actttctttc tgaaacggca gacactattg ttcacttgcg actggtcaaa
    18001 caccgtaaag aagcggaaac gctagtagag catttagact atgatagcta tagtgagcag
    18061 agaaaggcta attttgccaa acaaagtcag caagctgcta acaaccaaag agcctacgat
    18121 aaaaccatgg aaaaacatcg gagagttaag caaaatgtag aaactgcgct tcgagctacc
    18181 aaagatagta ctgccggtcg cctattggct aaaaagatga aaactgtcct ctcacaagaa
    18241 aaacgctacg aaaaggcagc tcagtccatg actcaaaagc cacttgaaga ggaacaaatc
    18301 caacttttct tttcagacat ccaaccatta ccagcttcta aagtcttagt ccaactggaa
    18361 aaagaaaatt tgtccattga cgaccgagtt ttggttcaaa aactacaact aactgtccgt
    18421 ggccaagaaa aaatcggtat tatcgggcca aatggtgttg ggaaatcaac tctgttagcc
    18481 aagttacaga gacttctgaa tgataaaaga gagatttcac ttggttttat gccacaagat
    18541 taccacaaaa aactgcaatt ggatttatcc ccaatagcct atctcagtaa aactggggaa
    18601 aaagaggaac tacagaaaat ccaatctcac ctagctagtc tcaatttcag ttatccagaa
    18661 atgcagcatc aaattcgctc cttatctggc ggacaacagg gaaaactcct gcttttggat
    18721 ttagtcctgc gcaaaccaaa ctttctcctg ctggatgaac ccacacgaaa cttttctccc
    18781 acttctcaac cccaaatcag aaaactcttt gctacctatc caggcggtct catcactgtt
    18841 tcgcatgacc gtcgtttctt aaaagaagtc tgctcgatca tctatcgcat gacagaacac
    18901 ggtttgaagc tagttaattt agaagattta taaatttgca acatagcaaa aatccagaga
    18961 cgacctctgg attcttttac atctgtttta aacgttcaat ccgttctgag ataggtgggt
    19021 gggtataaaa gagtttttgg aaccccccac ctttcttagg atcattgata taaagggcac
    19081 tgctagcatc atcgacgtgg cgactcatag gtttgctatt gtccaactta tctagggcat
    19141 taatcattcc ctggggattg cgagtcagct cgacactaga tgcatctgcc agaaattccc
    19201 tctgacgaga aatagcgagc tgaaccaagg ttgcagcgag aggtgccagt acaatagcta
    19261 gtagggaaac cactagcata atgatttcaa gaccatttcc atctcggtca tcatcacttc
    19321 gtctgcgacc tgctccaccc caccacatca tacgacctgc catactagaa agcatggtga
    19381 tagcactagc aagggcaact gcaatagtcg aaatacggat atcataatta cgaatatgac
    19441 tgacttcatg tcccataaca gcttctagtt cttcacgatt catgatagct agtagacctg
    19501 aagtcgcagc aacagccgca ttttgaggat tagaacctgt cgcaaaggca tttaaggctg
    19561 gatcatcaat gatgaaaaca cggggcatag gaatctgagc gaccagagcc atatcttcca
    19621 ctacatggta gaggtctggt gccgtttgct catccacctc acgcgctcca ttcatggaca
    19681 tgacaatctc tgtcgattga aaaatcatag acaaagcgta gataaagccg ataatcagtg
    19741 caataaccaa accaccaagt ccagatctta taaagagata accaaccgca taaccaacaa
    19801 gagctaagag taggaaaaat accagcaaca aaatccaggt ttttcgttta ttgcttgcaa
    19861 tttgatcaaa caacatctta gtcacctaaa ccgctaaaat caactttagg aaccgacttt
    19921 tcctcttcag gtgtttgaag gaaatctgcc gctttaaatc caaacattcc agcgataata
    19981 ttgctcggga aagtttctaa ttttacattg tagttgctga caacactgtt atagagttga
    20041 cgagagtaag aaattttatt ttctgtgttt gtcaactcct cttgcaattt aacaaagtta
    20101 gcactagctt tcaaatctgg atagctttct gcaactgcaa aaatacctga aacctgacga
    20161 gtgagggcat cactggcttt catagcttct gctggtgaag tcgctgccgc cacttggtta
    20221 cgtagttctg ccaccttttc aagggtagaa ccttcatatt tggcataacc ttttacagtc
    20281 tcaatcaagt ttggcaagag gtcattgcga cgtttcaact gaacatcaat ctgactccaa
    20341 gcctccttgg tttgcatacg atttttaacc aaaccgttat agctaacaat cacaaaaata
    20401 acaataagag cgataactcc aagaataatc caagtcataa tataagtcct ttctgctttt
    20461 agattagtac cagtatatca aattttctat gattgtggta aaataagatg atactaaaga
    20521 aggaaataac tatgaaacca aaaacatttt acaacttgct tgccgagcag aatcttccac
    20581 tttcggacca gcaaaaagaa caatttgaac gttattttga gctcttggtc gagtggaatg
    20641 agaagattaa tttgacggcg attacggaca aggaagaagt ttatctcaaa catttttacg
    20701 attcgattgc acccattctt caaggtttga ttcccaatga aactatcaaa cttcttgata
    20761 tcggggctgg ggcaggattt cctagtctac caatgaaaat tctctatccg gagttagatg
    20821 tgaccattat tgattcactc aataagcgca tcaacttcct acaactcttg gctcaagaac
    20881 tggatttgaa cggagttcat ttctaccacg gacgtgccga agattttgcc caagacaaga
    20941 acttccgtgc tcaatatgat tttgtaacag ctcgtgcggt tgcccgtatg caggtcctat
    21001 ctgaattgac tattccctac cttaaggttg gtggcaaact attagcactc aaggctagca
    21061 atgcgcctga ggaattatta gaagctaaga atgccctcaa tctccttttt agtaaggtcg
    21121 aagacaatct cagctacgcc ctaccgaata gagatccgcg ctatatcaca gtggtagaaa
    21181 agaaaaaaga aacaccaaat aaatatccac gtaaggctgg tatgccaaat aaacgcccac
    21241 tttaaatttt ttagtaaaca aatgtttaca aaatcagcct cgctctttta tttctaggct
    21301 cgggaaaaaa tgatttacaa aatcattttt ttctgctata ctatcctaag caaaggtttt
    21361 taatgtcatc ccgtgaggtg acgaagacgc agaaatattt aaaactcttt aaaatctaaa
    21421 ttttaaagaa gtcttactct gagggcctat tgctgtaaaa taatgggctc ttttttgatg
    21481 cccaaaagtg aggtttatat gaaacaagaa tcaactgttg atttgttact agacgttgac
    21541 caacgtcctt cggctggaaa aggaattctc cttagtttcc aacacgtttt cgccatgttt
    21601 ggtgcgacca tcttggtacc attgattttg ggaatgcctg tatctgttgc cctttttgct
    21661 tcaggtgttg gaacactcat ctacatgatt gctactggtt ttaaagttcc agtttatcta
    21721 ggttcttcat ttgcctttat cacagctatg tcactggcta tgaaagaaat ggggggggat
    21781 gtatctgctg cccaaacagg ggttatcttg actggtttgg tctatgtcct tgttgctacc
    21841 agcatccgat ttgtaggaac aaaatggatt gataaactct tgccaccaat cattatcggt
    21901 cctatgatca tcgttatcgg tcttggactt gcaggttcag ctgttaccaa tgcaggtctt
    21961 gtagcagacg gaaattggaa aaatgctctg gtagccgttg ttactttcct aattgctgcc
    22021 tttatcaata caaaaggaaa aggcttccta cgaatcattc cattcctctt tgccattatc
    22081 ggtggttacc ttttcgcact aactcttggc ttggttgact ttacaccagt tcttaaagcc
    22141 aactggttcg aaattcctgg tttctacttg ccatttagca caggtggtgc ctttaaagag
    22201 tacaatcttt actttggtcc agaagccatc gctatcttgc caatcgctat cgtaacaatt
    22261 tctgaacata tcggagacca tactgttttg ggtcaaatct gtggtcgtca attcttaaaa
    22321 gaaccaggtc ttcaccgtac tcttcttggt gacggtatcg caacttctgt ttctgccttc
    22381 cttggtggac cagccaatac aacttacgga gaaaatacag gggttatcgg tatgactcgt
    22441 atcgcttctg tctcagttat ccgtaacgct gccttcatcg cgattgccct cagcttcctt
    22501 ggtaaattca ctgccttgat ttcaactatt ccaaacgctg tacttggtgg tatgtcaatc
    22561 cttctctatg gggttatcgc cagcaatggt ttgaaagtct tgattaaaga acgtgttgat
    22621 ttcgctcaaa tgcgaaacct catcatcgca agtgctatgt tggttcttgg acttggagga
    22681 gctatcctta aacttggtcc agttacactt tcaggtactg ccctttcagc catgacagga
    22741 atcatcttga acttgatctt gccatacgaa aataaagact aagagtctaa atacacctaa
    22801 tccactcaga cagctgagtg gatttttcgt ataccataat aaaagtgtct taacaaaatt
    22861 attaaaatca aaaaacgtat aatatca
//
LOCUS       DAVFER010000033        22634 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1105170250
            SAMEA2167659-rid19724873.denovo.033, whole genome shotgun sequence.
ACCESSION   DAVFER010000033 DAVFER010000000
VERSION     DAVFER010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2167659
            Sequence Read Archive: ERR388902
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 22634)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22634)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928716.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928716.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 04:07:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,118
            CDSs (total)                      :: 2,073
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 120
            CDSs (without protein)            :: 120
            Pseudo Genes (ambiguous residues) :: 0 of 120
            Pseudo Genes (frameshifted)       :: 67 of 120
            Pseudo Genes (incomplete)         :: 47 of 120
            Pseudo Genes (internal stop)      :: 34 of 120
            Pseudo Genes (multiple problems)  :: 23 of 120
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22634
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2167659-rid19724873.denovo.033"
                     /strain="1105170250"
                     /db_xref="taxon:1313"
     gene            441..1802
                     /gene="trpE"
                     /locus_tag="VU534_001396"
     CDS             441..1802
                     /gene="trpE"
                     /locus_tag="VU534_001396"
                     /EC_number="4.1.3.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate synthase component I"
                     /protein_id="HEU1513974.1"
                     /translation="MERIIHGDVLSPILAYMRLKGQHKVILESIPRDKETARFSILAY
                     NPVFEIKFENGVLYQNGQVIDRDPLDFLYEVIHKSQHHSELPFGGGAIGFVGYDMISL
                     YEEIGQIPEDTIGTPDMHFFVYESYMVFDHKKEKIHVIEDALYSERSQEALEKSLNQV
                     LEELRIPAPNEFEDLDLSPLDFKPHIAPHKFEGMVETARDLIRNGDMFQCVLSQRFSA
                     EVTGNPFDFYRNLRVTNPSNYLYFYDFGDYQIIGASPESLVSVKNGIVTTNPIAGTRP
                     RGATDEEDKALATDLLSDEKETAEHRMLVDLGRNDIGRISETTSVQVTKYMEVELFRY
                     VMHLTSVVKGRLLPELTAMDALKATLPAGTVSGAPKIRAMRRIYELETEKRGVYAGAI
                     GYLSATGDMDLAIAIRTMILKNQRAYVQAGAGIVYDSIAQNEYQETINKAKSMTRIGE
                     LRP"
     gene            1799..2365
                     /locus_tag="VU534_001397"
     CDS             1799..2365
                     /locus_tag="VU534_001397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate/anthranilate synthase
                     component II"
                     /protein_id="HEU1513975.1"
                     /translation="MILLIDNYDSFTYNLAQYIGNFAEVQVLRNDDSKLYEEAEKADG
                     LVFSPGPGWPVDAGKMEDMIRDFAGKKPILGICLGHQAIAEVFGGKLGLAPKVMHGKQ
                     SNINFEAPSVLYQGIEDGRAVMRYHSILIEEMPEDFEVTARSTDDQAIMGIQHKNLPI
                     YGFQYHPESIGTPDGLSSIRNFIEEVVK"
     gene            2376..3380
                     /gene="trpD"
                     /locus_tag="VU534_001398"
     CDS             2376..3380
                     /gene="trpD"
                     /locus_tag="VU534_001398"
                     /EC_number="2.4.2.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate phosphoribosyltransferase"
                     /protein_id="HEU1513976.1"
                     /translation="MKEIIEKLAKFENLSGVEMTDVIERIVTGRVTEAQIASLLLALK
                     MKGETPEERTAIAQVMRGHAQHIPTEIHDAMDNCGTGGDKSFSFNISTTAAFVLAGGG
                     IHMAKHGNRSISSKSGSADVLEALGINLDLKPAELGKVFDKTGIVFLFAKNMHPAMKY
                     IMPARLELGIPTIMNLTGPLIHPMALETQLLGISRPELLESTAQVLKNMGRKRAIVVA
                     GPEGLDEAGLNGTTKIALLENGEISLSSFTPEDLGMEGYAMEDIRGGNAQENAEILLS
                     VLKNEASPFLETTVLNAGLGFYANGKIDSIKEGVALARQVIARGKALEKLRLLQEYQK
                     "
     gene            3377..4144
                     /gene="trpC"
                     /locus_tag="VU534_001399"
     CDS             3377..4144
                     /gene="trpC"
                     /locus_tag="VU534_001399"
                     /EC_number="4.1.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011227478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="indole-3-glycerol phosphate synthase TrpC"
                     /protein_id="HEU1513977.1"
                     /translation="MSQEFLARILEQKAREVEQMKLEQIQPLRQTYRLAEFLKNHQDR
                     LQVIAEVKKASPSLGDINLDVDIVQQAQTYEENGAVMISVLTDEVFFKGHLDYLREIS
                     SQVEIPTLNKDFIIDEKQIIRARNAGATVILLIVAALSEERLKELYDYATELGLEVLV
                     ETHNLAELEVAHRLGAEIIGVNNRNLTTFEVDLQTSVDLAPYFEEGRYYISESAIFTG
                     QDAERLAPYFNGILVGTALMQAENVAQRIKELQIDKG"
     gene            4131..4730
                     /locus_tag="VU534_001400"
     CDS             4131..4730
                     /locus_tag="VU534_001400"
                     /EC_number="5.3.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylanthranilate isomerase"
                     /protein_id="HEU1513978.1"
                     /translation="MTKVKICGLSTKEAVETAVSAGADYIGFVFAPSKRQVTLEEAAE
                     LAKLIPADVKKVGVFVSPSRVELLEAIDKVGLDLVQVHGQVADDLFENLPCASIQAVQ
                     VDGNGHVPNSQADYLLFDAPVAGSGQPFDWGQLDTTGLAQPFFIAGGLNEDNVVKAIQ
                     HFTPYAVDVSSGVETDGQKDHEKIRRFIERVKHGISGTK"
     gene            4708..5931
                     /gene="trpB"
                     /locus_tag="VU534_001401"
     CDS             4708..5931
                     /gene="trpB"
                     /locus_tag="VU534_001401"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit beta"
                     /protein_id="HEU1513979.1"
                     /translation="MAYQEPNKDGFYGKFGGRFVPETLMTAVLELEKAYRESQADPSF
                     QEELNQLLRQYVGRETPLYYAKNLTQHIGGAKIYLKREDLNHTGAHKINNALGQVWLA
                     KRMGKKKIIAETGAGQHGVATATAAALFNMECTIYMGEEDVKRQALNVFRMELLGAKV
                     EAVTDGSRVLKDAVNAALRSWVANIDDTHYILGSALGPHPFPEIVRDFQSVIGREAKQ
                     QYRDLTGRDLPDALVACVGGGSNAIGLFHPFVEDESVAMYGTEAAGLGVDTEHHAATL
                     TKGRPGVLHGSLMDVLQDAHGQILEAFSISAGLDYPGIGPEHSHYHDIKRASYVPVTD
                     EEALEGFQLLSRVEGIIPALESSHAIAFAVKLAKELGPEKSMIVCLSGRGDKDVVQVK
                     DRLEADAAKKGEAHA"
     gene            5924..6700
                     /locus_tag="VU534_001402"
     CDS             5924..6700
                     /locus_tag="VU534_001402"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit alpha"
                     /protein_id="HEU1513980.1"
                     /translation="MPKTLTEKLNAIKAAGKGIFVPYIMAGDHEKGLDGLAETIHFLE
                     DLGVSAIEVGIPFSDPVADGPVIEEAGLRSLAHGTSTQALVETLKTIETEIPLVIMTY
                     FNPLFQYGVENFVKDLADTAVKGLIIPDLPHEHANFVEPFLANTDIALIPLVSLTTGI
                     ERQKELIEGAEGFIYAVAINGVTGKSGNYRADLDKHLAQLHQVADIPVLTGFGVSSQA
                     DLERFNAVSDGVIVGSKIVKALHQGEPIQDFIRQAVAYQK"
     gene            complement(6672..6773)
                     /locus_tag="VU534_001403"
                     /pseudo
     CDS             complement(6672..6773)
                     /locus_tag="VU534_001403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000234126.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
     gene            7002..7733
                     /locus_tag="VU534_001404"
     CDS             7002..7733
                     /locus_tag="VU534_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000934015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1513981.1"
                     /translation="MLNQDLFDSLEAQKIVDTLMKGQKDYVDERLEKRETMIVSNGYA
                     WTRPNHIDTAFASADLFEYKLQLAGQTWGYLEFETNTEKYGKVLLIIKGKKRLTNQFP
                     LVQKNKSGYLFEYAQMNTLYLNQHSSYKNDENSHSFPIQMELVSDEMIQEIEQATKNS
                     NIEKFMILTYEADSENNIISVDVVMPDARTGQLHLIQDLSEYIQSSSYHFEEAKYQDI
                     PNFSELSETEDFEIIPRIEKQEGQK"
     gene            7748..8899
                     /locus_tag="VU534_001405"
     CDS             7748..8899
                     /locus_tag="VU534_001405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000481741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HEU1513982.1"
                     /translation="MFNGRVLKELRLLNGLSRAELAQRINLTEQAIWQFESNETKPKL
                     STKMHLANQFHVDLTYFEQEEESIRFDSSVIAFRNADLATRKTIDIQTMYLHKVDSLI
                     DYFESFVIIPNIIIHDLSNVVSESYHKGESIEELALYAREKLGISKDNHDLLYKLERS
                     GIYIVERLINGQADAYSAWSKLGRPYIVLGTNKSSVRRNFDLAHELGHILLHKYKDMN
                     EDGDRLEQEANYFASCFLLPKEEFLVKFEERVGKRVSNPDSYILLKSDLNVSIQALEY
                     RAFKLGLLTPKQHSYFYRQIAQKGYKMIEPLDDQIFVKKPSKVKSILDVVLSNHLVSL
                     ATIMSKQSIRLQFISEIFSVEMKFFDQYQEDRRTDRFDNIIPLYKRNNL"
     gene            complement(8951..9610)
                     /locus_tag="VU534_001406"
     CDS             complement(8951..9610)
                     /locus_tag="VU534_001406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000564993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HEU1513983.1"
                     /translation="MIDFYFFLVGSILASFLGLVIDRFPEQSIISSASHCDSCQTPLR
                     PLDLIPILSQVFNRFRCRYCKVRYPVWYALFELSLGLLFLLYSWGWLSLGQVVLITAG
                     LTLGIYDFHHQEYPLLVWMTFQLILIASSGWNLVMVSFLILGILAHFIDIRMGAGDFL
                     FLASCALVFSVTELLILIQFASATGILAFLLQKKKERLPFVPFLLLATCLIIFGKLLL
                     V"
     gene            9680..10126
                     /locus_tag="VU534_001407"
     CDS             9680..10126
                     /locus_tag="VU534_001407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000155432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU1513984.1"
                     /translation="MTIRFEEKVSTENAQFVCQWSNSLGKSFQEQWMGPRIPFLLTLQ
                     ALEGVFSIFDEQEFVGFIQKIRLEDSNLHIGRFFINPQKQEQGLGSKALRKFVSLAFE
                     NRDIDSISLNVFEANQRAQNLYQKEGFEIVQMVEAPVRKYSRLKLE"
     gene            10271..10543
                     /locus_tag="VU534_001408"
                     /pseudo
     CDS             10271..10543
                     /locus_tag="VU534_001408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000547411.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(10653..10856)
                     /locus_tag="VU534_001409"
     CDS             complement(10653..10856)
                     /locus_tag="VU534_001409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HEU1513985.1"
                     /translation="MSVEEKLNQAKGSIKEGVGKAIGDEKMEKEGAAEKVVSKVKEVA
                     EDAKDAVEGAVEGVKNMLSGDDK"
     gene            complement(10887..11495)
                     /locus_tag="VU534_001410"
     CDS             complement(10887..11495)
                     /locus_tag="VU534_001410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000064115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEU1513986.1"
                     /translation="MSNEKNTNTNVEKKDATVVAHEIKGELTYEDKVIQKIIGLSLEN
                     VSGLLGIDGGFFSNLKEKIVNSDDVTSGVNVEVGKTQVAVDLNVIVEYQKNVPALYSE
                     IREIVSSEVAKMTDLEIVEINVNVVDIKTKEQHEADSVSLQDRVSDVAESTGEFTSEQ
                     FEKAKSGLGSGFSTVQEKVSEGVEAVKGAANGVVSHENTRVN"
     gene            complement(11534..11704)
                     /locus_tag="VU534_001411"
     CDS             complement(11534..11704)
                     /locus_tag="VU534_001411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HEU1513987.1"
                     /translation="MEWLKQYRYPIIAGLIGVFLACLIVSFGFFKTIFVLILGALGVA
                     AGLYIEKNYIDK"
     gene            complement(11716..12282)
                     /gene="amaP"
                     /locus_tag="VU534_001412"
     CDS             complement(11716..12282)
                     /gene="amaP"
                     /locus_tag="VU534_001412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000030212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HEU1513988.1"
                     /translation="MSKAKKICFIIFCILILTIFLPVLIDYHQVSDLGIHLLSWRQNS
                     VVEFYLARYVFWGTVVLSTLVLLSILVVMFYPKRYLEIQLETKNDTLKLKNSAIEGFV
                     RSLVSDHRLIKNPTVHVNLRKNKCFVHVEGKILPSDNIADRCQIIQNEITNGLKQFFG
                     IERQVKLEVAVKNYQPKPQNKKTVSRVK"
     gene            complement(12366..12530)
                     /locus_tag="VU534_001413"
     CDS             complement(12366..12530)
                     /locus_tag="VU534_001413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HEU1513989.1"
                     /translation="MGIIANVFAGLVGAYAGQSLLGSWGPAIAGMALLPSIVGAAIVI
                     TVVSFFTGRK"
     gene            12973..14454
                     /locus_tag="VU534_001414"
     CDS             12973..14454
                     /locus_tag="VU534_001414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001205273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEU1513990.1"
                     /translation="MRDLLSKKSHRQLELLELLFEHKRWFHRSELAELLNCTERAVKD
                     DLSHVKSAFPDLIFHSSTNGIRIINTDDSDIEMVYHHFFKHSTHFSILEFIFFNEGCQ
                     AESICKEFYISSSSLYRIISQINKVIKRQFQFEVSLTPVQIIGNERDIRYFFAQYFSE
                     KYYFLEWPFENFSSEPLSQLLELVYKETSFPMNLSTHRMLKLLLVTNLYRIKFGHFME
                     VDKDSFNDQSLDFLMQAEGIEGVAQSFESEYNISLDEEVVCQLFVSYFQKMFFIDESL
                     FMKCVKKDSYVEKSYHLLSDFIDQISVKYQIEMENKDNLIWHLHNTAHLYRQELFTEF
                     ILFDQKGNTIRNFQNIFPKFVSDIKKELSHYLETLEVCSSSMMVNHLSYTFITHTKHL
                     VINLLQNQPKLKVLVMSNFDQYHAKFVAETLSYYCSNNFELEVWTELELSKESLEDSP
                     YDIIISNFIIPPIENKRLIYSNNINTVSLIYLLNAMMFIRLDE"
     gene            14816..15817
                     /locus_tag="VU534_001415"
     CDS             14816..15817
                     /locus_tag="VU534_001415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000230206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEU1513991.1"
                     /translation="MVEQRKSITMKDVALEAGVSVGTVSRVINKEKGIKEVTLKKVEQ
                     AIKTLNYIPDYYARGMKKNRTETIAIIVPSIWHPFFSEFAMHVENEVYKRNNKLLLCS
                     INGTNREQDYLEMLRHNKVDGVVAITYSPIEHYLTSGIPFVSIDRTYSDIAIPCVSSD
                     NDAGGREAAKQLISKGCQHLAFVGGHNTTINETKRRRISFEKYVQEHKIPLSIFDLDE
                     TVTDYYGKLESFLEENSSIDGIFTINDFTALDVIEILEKNGKRIPHDVQIIGYDGIKM
                     AGDRDYLLSTIEQPLEEMAKEAVRILFDIIDGKTVNLQTILPVKFVEGKTTKNENKS"
     gene            15968..16885
                     /locus_tag="VU534_001416"
     CDS             15968..16885
                     /locus_tag="VU534_001416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001084977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEU1513992.1"
                     /translation="MNSKAKQVSLWERIKKQKLLLLMTVPGLVLTFIFKYIPMYGVLI
                     AFKDYNPLKGILGSDWIGFSEFTKFISSPNFGILLANTLKLSIYGLLLGFLPPIILAI
                     MLNQLLSEKVKKRIQLILYAPNFISVVVIVGMIFLFFSVGGPINNFLSMFGMKADFLT
                     NPDFFRPLYIFSGIWQGMGWASTLYTATLVNVDPALVEAARLDGANIFQRIWHIDIPA
                     LKPIMVIQFVLAAGGIMNVGYEKAFLMQTSLNLPTSEIISTYVYKVGLVSGDYSYSTA
                     VGLFNAVINVVLLVAVNQIVKRMNNGEGI"
     gene            16896..17786
                     /locus_tag="VU534_001417"
     CDS             16896..17786
                     /locus_tag="VU534_001417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000797960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEU1513993.1"
                     /translation="MKNSIMDTKFDRRILLLNKIIIVFIVLMTLLPLLYIVVASFMDP
                     KVLVSRGISFNPADWTVEGYQRVFSDQSILRGFINSLLYSFGFAALTVLLSVFTAYPL
                     SKKDLVGRRWINYFLIVTMFFGGGLVPTYLLVKELGMLNTPWAIIVPGAVNVWNIILA
                     RAYFQGLPEELVEAAVIDGANDLQIFFKIMLPLAKPIMFVLFLYAFVGQWNSYFDAMI
                     YIKDPNLEPLQLVLRKILIQSQPGQDMIGAQAAMNEMKRLAELIKYATIVISSLPLIV
                     MYPFFQKYFDKGIMAGSLKG"
     gene            17815..19431
                     /locus_tag="VU534_001418"
     CDS             17815..19431
                     /locus_tag="VU534_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEU1513994.1"
                     /translation="MKFKTFSKSAVLLTASLAVLAACGSKNTASSPDYKLEGVTFPLQ
                     EKKTLKFMTASSPLSPKDPNEKLILQRLEKETGVHIDWTNYQSDFAEKRNLDISSGDL
                     PDAIHNDGASDVDLMNWAKKGVIIPVEDLIDKYMPNLKKILDEKPEYKALMTAPDGHI
                     YSFPWIEELGDGKESIHSVNDMAWINKDWLKKLGLEMPKTTDDLIKVLEAFKNGDPNG
                     NGEADEIPFSFISGNGNEDFKFLFAAFGIGDNDDHLVVGNDGKVDFTADNDNYKEGVK
                     FIRQLQEKGLIDKEAFEHDWNSYIAKGHDQKFGVYFTWDKNNVTGSNESYDVLPVLAG
                     PSGQKHVARTNGMGFARDKMVITSVNKNLELTAKWIDAQYAPLQSVQNNWGTYGDDKQ
                     QNIFELDQASNSLKHLPLNGTAPAELRQKTEVGGPLAILDSYYGKVTTMPDDAKWRLD
                     LIKEYYVPYMSNVNNYPRVFMTQEDLDKIAHIEADMNDYIYRKRAEWIVNGNIDTEWD
                     DYKKELEKYGLSDYLAIKQKYYDQYQANKN"
     gene            19441..20760
                     /locus_tag="VU534_001419"
     CDS             19441..20760
                     /locus_tag="VU534_001419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HEU1513995.1"
                     /translation="MGDKKYTVEKANRFIAENKHLVNTQYKPEEHFSAEIGWINDPNG
                     FVYFRGEYHLFYQFYPYDSVWGPMHWGHAKSKDLVTWEHLPVALAPDQDYDRNGCFSG
                     SAIVKDDRLWLMYTGHIEEETGVRQVQNMVFSDDGIHFEKISQNPVATGSDLPDELIA
                     ADFRDPKLFEKDGRYYSVVAAKHKDNVGCIVLLGSDNLVEWQFESIFLKGGEHQGFMW
                     ECPDYFELDGKDCLIMSPMRYQREGDSYHNINSSLLFTGKVDWREKRFIPESVQEIDH
                     GQDFYAPQTLLDDQNRRILIAWMQTWGRTLPTHDQEHKWACAMTLPRILRLEDGKLRQ
                     FPVKKGQYQIQIDKDCHYHLGNDIDYLEFGYDSNAQQVYIDRSHLIQKILGEEEQDTS
                     RRYVDIEAKELEVVLDKNSIEIFVNQGEASLTATYYLTVPAELSRID"
     gene            21158..21571
                     /locus_tag="VU534_001420"
     CDS             21158..21571
                     /locus_tag="VU534_001420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000794280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1513996.1"
                     /translation="MKNNERLGIKLSRDSVLGLREVRRLYLGSSDIPVSDGYVIEVAY
                     NQISHEIDIIDWVELNKSKIKISEISESVDIDATSLRTTLTLDTLVYEGMRDIQLKLR
                     ELTKGRVFFSFVVKLVLFASILKKKDLLEKFQEKC"
     gene            21822..22397
                     /locus_tag="VU534_001421"
     CDS             21822..22397
                     /locus_tag="VU534_001421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000810872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1513997.1"
                     /translation="MKQKQPIVSRTKQHTFEELIQDQKLERLAKLSPDLVGRYGFTAS
                     CASSFANLIKEAYGGKNLNVVYASRMLALWNIACSCYHKADGYSLADALFSDKKICLD
                     SYYYHKNTSNTITSDVIKDVYDNYNNYMVLTREATPEYIYVVQTEMPKDSDLYFYIRE
                     VLGLSFSTMHYAFLVKVLAGALARKYKPYRN"
BASE COUNT         7290 a         3850 c         4656 g         6838 t
ORIGIN      
        1 acctacggca aggcgacgtt gacgcggttt gaagagattt tcgaagagta taaaggtgta
       61 ccgagatgaa catctcttca tcaatgtctc tggtcgtgga ggcaaggacc tagctgcgat
      121 tgcagactac tagaagctaa aaaataatag atggaaaaat tacagttctt tctctcacag
      181 agagcttgtg gttgctgaaa acaagcagag aaagctgtaa agttgggttc atctgaaacg
      241 agagaagaaa acatcattct caagggagtg ccctttatcg cacagcctgt tacaggagat
      301 atctgagaca ggaatgagag ataggagaaa tcctataatt gaggtggcac cgcgaatttc
      361 gtcctcacgc aagttatttt gcgtggggat ttttcataca gtcaccacgg actagaagta
      421 gaactgaaag ggaaattaca atggaacgaa tcattcatgg agatgtctta tcaccaatct
      481 tggcttatat gcgcttaaag gggcaacata aggttatttt agagagtatt ccgagagaca
      541 aggaaacagc tcgtttttct atcctagcct ataatccagt ttttgagatt aagtttgaaa
      601 atggggttct ctatcaaaat ggtcaagtga ttgatcggga tcccttggat ttcctttatg
      661 aagtgattca taagagtcag caccactcag agctaccttt tggtggtgga gccattggtt
      721 ttgtgggtta cgatatgatt tcgctttatg aagaaattgg tcaaatccct gaggatacaa
      781 ttgggacgcc agacatgcat ttctttgtct atgagagcta tatggtcttt gaccacaaga
      841 aggagaagat acatgtcata gaggatgcac tttatagtga gcgcagtcaa gaggccttgg
      901 aaaaatcctt gaaccaagtg cttgaggaat tacgcattcc tgctccaaat gaatttgaag
      961 atttggatct atctccgtta gacttcaaac cgcatatcgc tccacataag tttgagggaa
     1021 tggtagaaac agctcgtgac ttgattcgta acggagatat gttccaatgt gtactcagcc
     1081 agcgtttttc agcagaagtt actggaaatc catttgactt ctacagaaat ctccgcgtga
     1141 ctaatccttc taattacctt tatttctatg attttgggga ttatcaaatc atcggagcta
     1201 gtccagaaag tttggtttct gtcaaaaatg gcatcgtgac aaccaatccg attgcaggga
     1261 cgcgaccaag aggggctacg gatgaagaag acaaggcctt ggcgactgac ctcctctctg
     1321 atgagaagga aacagcagaa catcgaatgt tggtagactt ggggcgtaac gatattggcc
     1381 gcatctctga aacgaccagt gtccaagtca ctaagtatat ggaagtggag ctcttccgct
     1441 acgtcatgca tttgaccagc gtagtcaagg ggcgtttgct tccagaactc actgccatgg
     1501 atgccttgaa agcaacgctt cctgctggaa ccgtttctgg agcaccaaag attcgagcga
     1561 tgagacgtat ctatgaactg gaaacggaaa aacggggagt atacgctggg gcaatcggct
     1621 acttgtctgc gacgggtgat atggatttgg ccatcgccat ccgaaccatg attctcaaaa
     1681 atcaaagagc ctatgtgcag gctggggcag ggattgtcta cgactctatc gcccaaaacg
     1741 aataccaaga aaccattaac aaagcaaaat ctatgactag aattggagaa ctaagaccat
     1801 gattttattg attgacaact atgattcttt tacctataac ttggcccaat acattgggaa
     1861 ttttgcagaa gttcaggttc tgagaaatga tgattccaag ctgtatgaag aagctgaaaa
     1921 agcagatggt ctggtctttt ctcctggtcc tggttggcca gttgatgctg gaaagatgga
     1981 agacatgatt cgtgattttg caggcaagaa gccgattctt gggatttgtt tgggccacca
     2041 agccattgca gaagtctttg gtggtaagct aggtttggct ccaaaagtca tgcatgggaa
     2101 acagagcaat atcaactttg aagcgccatc tgttttgtat caaggtattg aggatggccg
     2161 tgcggtcatg cgttatcaca gtattttgat tgaggaaatg ccagaagact ttgaagtgac
     2221 agctcgttcg actgatgacc aagccatcat ggggattcaa cataaaaacc taccgattta
     2281 tggcttccag taccatccag agagcattgg aacgccagac ggcttgtctt ctattcggaa
     2341 ttttatcgag gaggttgtaa agtgaggaaa ctaggatgaa agagattatt gaaaaactag
     2401 caaaatttga aaatttatca ggtgtggaaa tgacggatgt cattgagcgt atcgtaactg
     2461 ggcgtgtaac tgaagcgcag attgcttctc tcctcttagc tcttaagatg aagggggaaa
     2521 cacctgaaga acgcacagcc attgcccaag tcatgagagg acatgcccag catattccaa
     2581 ctgagattca tgatgccatg gacaactgtg gtacaggtgg ggacaagtct ttcagtttta
     2641 atatttccac aactgcagcc tttgtcttgg ctggtggcgg tattcacatg gccaaacacg
     2701 gtaaccgctc gatatcttct aaatctggtt ccgcagatgt cctcgaagcc ttgggaatca
     2761 atcttgacct caaaccagct gaactaggta aggtctttga taaaactgga atcgtctttc
     2821 tcttcgctaa aaatatgcac ccagctatga aatacatcat gccagctcgt ttggaattgg
     2881 gaattccaac gattatgaac ttgactggtc cactgattca tccaatggct ttagaaacac
     2941 agcttcttgg aattagtcgt ccagaactcc tagaaagtac agctcaggtt ttgaaaaata
     3001 tgggtcgcaa acgtgccatc gtggttgctg gaccagaagg gttggatgaa gctggcttga
     3061 acggaacaac caagattgca cttcttgaaa atggcgaaat cagcttgtca agctttactc
     3121 cagaggattt gggaatggaa ggctatgcta tggaagatat tcgtggtggg aatgctcagg
     3181 aaaatgcaga aattttgctt agcgttctga aaaacgaagc aagtccattc ttggaaacga
     3241 cagtcttgaa tgctggtctt ggtttctatg ctaatggtaa gattgatagc atcaaggaag
     3301 gggttgcctt ggcccgtcaa gtgattgcta gaggcaaggc ccttgaaaaa ctcagactgt
     3361 tacaggagta ccaaaaatga gtcaggaatt tttagcacga atcttagagc agaaggcgcg
     3421 tgaggtggag cagatgaagc tggagcaaat ccagcctctg cgccagacct atcgcttggc
     3481 agaatttttg aagaatcatc aggaccgctt gcaggtaatc gctgaggtca agaaagctag
     3541 ccctagtttg ggagatatca atctcgatgt ggatattgtg caacaggccc agacttatga
     3601 agaaaacgga gcagtgatga tttcggtgtt gacagatgag gttttcttta aagggcattt
     3661 ggattatcta cgggaaattt ccagtcaggt agagattccg acgctcaaca aagactttat
     3721 catcgatgaa aagcaaatca tccgcgctcg caatgcaggt gcgacagtta tcttgctcat
     3781 tgtggcagcc ttgtccgaag aacgcctcaa ggaactgtat gactacgcga cagagcttgg
     3841 tctggaagtc ttagtggaga ctcacaatct agctgaacta gaggtagccc acagacttgg
     3901 tgctgagatt atcggggtca acaaccgcaa cttgactacc tttgaggtcg acttgcagac
     3961 cagtgtagat ttagcccctt actttgagga aggtcgctat tacatttctg aatctgccat
     4021 tttcacaggg caggatgcgg aacgactagc cccatacttt aacggaattt tggtagggac
     4081 agctcttatg caggcagaaa atgtggccca gagaatcaag gagttgcaga ttgacaaagg
     4141 ttaaaatttg tggactatcg accaaagaag cggtggaaac agccgtttca gcaggagccg
     4201 actatatcgg ttttgtcttt gcacctagta aaagacaggt gactttagaa gaggcagctg
     4261 agttggcaaa gcttattcct gcagatgtga aaaaggttgg agtatttgtt tcaccaagtc
     4321 gggtagaact gctggaagcg attgacaaag ttggcttgga cttggttcaa gttcacggtc
     4381 aggtggcaga tgatttattt gagaatttgc cttgtgccag tattcaggct gtgcaggtag
     4441 atggaaatgg gcatgtcccc aattctcagg cagattatct actctttgat gcccctgtgg
     4501 caggaagtgg ccagcccttt gattggggtc aactggatac gactggacta gcacagccct
     4561 tctttatcgc aggtggcctt aatgaagata atgtagtaaa agcaattcaa cactttactc
     4621 cctatgcagt agatgtatcg agcggagtgg agacagatgg acaaaaagat catgaaaaga
     4681 ttagaagatt tatagagagg gtaaagcatg gcatatcagg aaccaaataa agatggattt
     4741 tacggaaaat tcggcggacg ttttgtccca gaaacattga tgacagcagt tttggagttg
     4801 gagaaggcct accgtgaaag tcaggcagac ccaagtttcc aagaggaatt aaaccagctt
     4861 ttgcgccagt acgtaggacg tgaaactcct ctttattacg caaaaaactt gacccagcat
     4921 attggcggag ccaagattta tctcaaacgg gaagacctta accatacagg agcccacaag
     4981 attaacaatg ccttaggaca agtttggctt gccaaacgca tgggtaaaaa gaaaattatc
     5041 gcagaaacgg gtgctggtca gcacggtgtg gcaactgcaa ctgctgcagc cctctttaac
     5101 atggaatgta ccatctacat gggtgaggaa gatgtcaaac gccaagccct caatgtcttc
     5161 cgcatggagc ttttgggagc caaggtcgag gctgtaacag atggttcgcg cgtgctcaag
     5221 gatgcggtca atgcagccct tcgttcatgg gtggctaata tcgacgatac ccactatatc
     5281 cttggttctg ccttggggcc tcatccattt ccagaaatcg ttcgtgactt ccaaagtgtc
     5341 atcggtcgag aggctaaaca acagtaccgt gacttgacag gtcgagatct gccagatgcc
     5401 ctagtagcct gtgttggtgg tgggtcgaat gctatcgggc tcttccatcc ctttgtagaa
     5461 gatgagtcag tagctatgta tggaactgaa gcagcagggc ttggtgtgga tacagagcac
     5521 cacgcagcta ccttgaccaa gggtcgtcca ggtgtccttc acggttccct catggatgtg
     5581 ctccaagatg cccatggtca aattcttgaa gccttctcta tctcagcagg tttggactat
     5641 cctggtatcg gtccagagca ttctcactac cacgatatta aacgtgccag ctatgtccct
     5701 gtgacagacg aagaagcctt ggaaggattc caactcttgt ctcgtgtgga agggattatc
     5761 ccagccttgg aatctagcca tgctatcgcc tttgcggtga aattggccaa agaacttgga
     5821 ccagaaaagt ctatgattgt ctgcctatca ggtcgtgggg acaaggatgt ggttcaagtc
     5881 aaggaccgct tggaagcaga tgcagcaaag aagggagaag ctcatgccta agacactaac
     5941 agaaaaatta aatgctatta aagcagctgg aaaaggaatt tttgttccct atatcatggc
     6001 tggtgaccac gagaaaggtt tggacggtct tgctgaaaca attcactttt tagaagattt
     6061 gggtgtctct gcaattgaag tgggtattcc cttttcagac cctgttgcag atggacctgt
     6121 tatcgaagaa gctggcttgc gcagtttagc ccacgggacc tctacccagg ctttagttga
     6181 aaccttgaaa accattgaaa cagagattcc actggtcatc atgacctact tcaaccccct
     6241 ctttcagtac ggtgtggaga actttgtcaa agatctggct gatacagctg tgaagggctt
     6301 gattatccca gacctgcctc atgaacatgc caactttgta gaaccatttt tggcaaatac
     6361 agatatcgcc ttgattcctt tagtaagctt gaccacagga attgagcgcc agaaagagtt
     6421 gattgaaggg gcggagggat tcatctatgc cgttgccatc aatggagtga cagggaaatc
     6481 aggcaattac cgtgcagatt tggacaagca cttggcgcaa cttcatcaag tggccgacat
     6541 cccagtcttg acaggttttg gtgtatctag tcaagccgat ctggaacgct tcaatgcggt
     6601 gtcagatggt gttatcgtcg gttcgaaaat agtaaaagct ctccaccaag gagagccgat
     6661 tcaggatttt atcagacaag cagtagctta ccaaaaataa tcaaacaagt agcaagtaag
     6721 aggaaaggca cgaaaggaag tctttccttt ttcttttgca ggagaaaggt cagttttata
     6781 gtgaattgaa tctggaatat tacactacgg ttcctaaaat attttcagaa agcgatttga
     6841 atttcccaat aaatttgttc agtttttaat tgattttact atagaagata taattttcta
     6901 aattactctg acacagaact ttaagaaaaa gataattatt gtagtaattt ctttaagaaa
     6961 atggtataat tcattaaaaa gtatttggag gaggaagaat tatgttgaat caggatctct
     7021 ttgattcgct tgaggcacaa aaaattgtag atactttgat gaaagggcaa aaagattatg
     7081 tagatgaacg tctagaaaaa agagagacaa tgatagtgtc gaatggttat gcatggacgc
     7141 gacctaatca tattgatact gcatttgcat cagcagattt gtttgagtat aaattacaat
     7201 tagcaggaca gacttgggga tatttagaat ttgaaacaaa tacagaaaaa tatgggaaag
     7261 tattgttaat tataaagggt aagaagcgac ttacaaacca atttcctttg gtacaaaaaa
     7321 ataagagtgg ctacttattt gaatatgctc agatgaatac actttatctt aatcaacatt
     7381 cttcctacaa aaatgatgaa aatagtcatt cctttccaat tcagatggag ttagtttctg
     7441 atgaaatgat tcaagaaatt gaacaagcta ctaaaaattc gaatatcgaa aaatttatga
     7501 ttttaactta tgaggcggac tcagaaaaca atattatatc tgtagatgtt gttatgcctg
     7561 atgcacgaac tggtcagtta cacttgattc aagatttgtc tgagtatatt caatcaagtt
     7621 cgtaccattt cgaagaagct aaatatcaag atattcctaa tttttcagaa ttatcggaaa
     7681 cagaagattt tgaaattatt ccaagaatag aaaaacaaga aggtcaaaag tagtaaggag
     7741 tatgtaaatg tttaatggtc gggtattgaa agaattacgg ctgttaaatg gtttaagtag
     7801 agcagaatta gctcagagaa ttaatttaac ggaacaagcc atttggcagt ttgagtccaa
     7861 cgaaacgaaa cctaaattat caaccaaaat gcatttggcc aaccaatttc atgttgattt
     7921 aacttatttt gaacaggaag aagagagcat tcgatttgat tcttctgtaa ttgcctttag
     7981 aaatgcagac ctagcaacac ggaaaacaat agatattcaa actatgtatt tacataaggt
     8041 agatagtttg attgattatt ttgaaagttt tgtaattata cctaatatta taattcatga
     8101 cctaagtaat gtagtgagtg aatcttatca taagggagaa tccattgagg aattggctct
     8161 ttatgccagg gaaaaattag gtatttcaaa agataatcat gatttgcttt ataaattaga
     8221 acgttcaggc atctatatcg tggaacgatt aattaatggc caagctgatg cttatagcgc
     8281 atggtcaaaa ttgggaagac cttatattgt gttaggaacg aataaatcat ctgtacgtcg
     8341 aaattttgac ttagctcatg agctaggaca tattctttta cataaatata aagatatgaa
     8401 tgaagatggc gatcgtttgg agcaagaagc aaattatttt gcatcatgtt ttttattgcc
     8461 aaaagaagag tttttagtca aatttgaaga gagggttggc aagcgtgtca gcaatcctga
     8521 tagttatatt ttattgaagt cggatttgaa tgtttcgata caggctttag agtatcgagc
     8581 ttttaagtta ggattattga ctccaaagca acattcttac ttttatcgtc aaattgcgca
     8641 aaaaggttac aaaatgattg aacccttgga tgatcaaatt tttgttaaaa aaccaagcaa
     8701 agtaaagagt attctggacg tcgttttgag taatcatcta gtcagtctag cgactataat
     8761 gtctaaacaa agtattcgtt tacagtttat aagcgaaata ttttcagtcg aaatgaaatt
     8821 ttttgatcag tatcaagaag atagaagaac agatcgattt gataacatca tccctttgta
     8881 caaaagaaat aatttataat ttaactgtga aataatttca tgaaggatat atggcagaaa
     8941 ttggatttta tcagacaagc agtagcttac caaaaataat caaacaagta gcaagtaaga
     9001 ggaaaggcac gaaaggaagt ctttcctttt tcttttgcag gagaaaggcc aggatacccg
     9061 tcgcagaagc gaactgaatc aagatcagta actccgttac gctaaagacg agagcacaag
     9121 aagctaaaaa gaggaaatcc cctgcaccca tgcggatatc gataaaatga gccaaaattc
     9181 caagtatgag gaaggagacc atgaccagat tccagccaga ggaagctatt aggattagct
     9241 ggaaagtcat ccagaccagt aagggatatt cctgatggtg aaagtcgtag atacccaagg
     9301 tcaaaccagc ggtgattagg acgacttgcc ccaaggagag ccatccccaa gagtaaagca
     9361 gaaagaggag tcctaagctt aattcaaaga gggcatacca gacaggatag cgaactttgc
     9421 agtagcgaca gcgaaagcga ttgaagacct gtgagagaat cggaatcaaa tctaagggac
     9481 gcaagggagt ctgacaggaa tcgcagtgac tggctgaact gataatggat tgctctggaa
     9541 aacggtcaat gaccaaacca agaaaggaag ctagaatgct cccgacgaga aaaaaataaa
     9601 aatcaatcat acttatctat tcgtaaaaaa tgggagaaat agtataatgg agaaacatag
     9661 ataaggtggt gaggaaaaga tgacaattcg ttttgaagaa aaggtgagca cagaaaacgc
     9721 tcaatttgta tgccagtggt ccaactccct aggcaaatcc tttcaagaac aatggatggg
     9781 accaaggatt ccttttctac tgacacttca agccttggaa ggagtctttt caatctttga
     9841 tgaacaagag tttgtgggat ttatccagaa aatcaggcta gaagacagca atcttcatat
     9901 cgggagattt tttatcaacc cccagaaaca ggagcaaggc ttaggtagca aggctttaag
     9961 gaaatttgtt agtttagcat ttgaaaatag agatatagac agtatttctc taaatgtctt
    10021 cgaggcaaat caaagagctc agaatcttta ccaaaaagaa ggatttgaaa tcgttcaaat
    10081 ggttgaagca cctgtacgaa aatatagtag attgaaacta gaatagtaca cctctacttc
    10141 taaaacattg ttagaaatcg atttgactgt cccgatcaat tcgtcctgtt attatttcat
    10201 tttattatac attatgaaaa aggggagata gaaagcaaac agccttgaaa tcaatgttga
    10261 ctgcgattat gaacctgaat cagcccctca aaagagactg tatatgaatg aacgttacca
    10321 gtgtttaaaa actaaagaat atcaggcact tttatcttcc aagggtagac aaattttcgc
    10381 taaacgtaag attgatatga aatctgtctt tgggcagata aaggtttgtt tgggttataa
    10441 gagatgtcat ctgagaggta agcgtcaagt gagaattgac atgggattcg tactcatggc
    10501 caacaacctg ctgaaatata ataagagaaa gaggcaaaat taaaaagcta gagttccgca
    10561 attgggaatc tctagctttt tgttttctga gaatcatctt gactcagact cttttgacta
    10621 atattactaa aaagataaag taacttttaa ccttatttat cgtcgccact caacatgttt
    10681 ttaacacctt ctacagcacc ttctacagcg tctttagcgt cttcggcaac ttcttttact
    10741 ttagaaacaa ctttttcagc tgcaccttct ttttccattt tttcatcacc gatggctttc
    10801 ccaacacctt ctttaataga acctttagct tgatttaatt tttcttctac tgacatgata
    10861 atttctcctg ttatatttat tttatcttag tttacacgag tgttttcgtg agatactaca
    10921 ccatttgctg cacctttaac agcttctaca ccttcgctaa ctttttcttg aacagttgag
    10981 aaaccagatc caagaccaga tttagctttt tcgaattgtt ctgaagtgaa ttctcctgtt
    11041 gattcagcaa cgtcagatac gcgatcttga aggcttactg agtctgcttc atgctgttct
    11101 ttagttttga tgtcgacaac gtttacgttg atttcaacaa tttccaagtc agtcatttta
    11161 gcaacttctg aagatacgat ttctctgatt tctgaatata aagctggaac atttttttgg
    11221 tactcaacaa taacgtttaa gtcaactgca acttgtgttt taccaacttc tacgttaaca
    11281 ccacttgtta cgtcatcgct gttaacgatt ttttctttaa gatttgagaa gaaaccacca
    11341 tcgattccca aaagacctga aacgttttct agtgaaagac caatgatttt ttggataact
    11401 ttatcttcgt aagtaagttc ccctttgatt tcgtgagcta caacagtagc atctttcttt
    11461 tctacgttag tgtttgtgtt tttttcgttt gacatatgaa actcctttaa ttaaattagt
    11521 aatttttatt tttttattta tctatatagt ttttttcgat atataatcca gctgcaactc
    11581 ccagtgctcc taaaatcaat acaaatattg ttttgaagaa gccaaaggag acaatcaaac
    11641 aagccagaaa tacgcctatg agaccagcga taattggata tcgatattgt ttaagccatt
    11701 ccatttttta cttccttact tcacacgact aacagtcttt ttgttttgag gttttggttg
    11761 gtaatttttt actgcaactt caagttttac ttgacgctca ataccaaaaa actgcttcaa
    11821 tccattagtt atttcatttt gaattatttg gcatctgtca gcgatgttgt ctgaaggaag
    11881 aattttacct tctacatgaa cgaaacattt attttttcgt aaatttacat gaacagttgg
    11941 gttcttgatc aatctatgat cactcaccaa acttctaaca aaaccttcga ttgccgaatt
    12001 ctttaatttt aatgtatcgt ttttagtttc aagttggatt tccaagtaac gtttaggata
    12061 aaacatcaca actaaaatgg ataataaaac taaagttgat agaaccactg tcccccaaaa
    12121 gacatatcta gcaagataga attcaactac ggagttctgt ctccagctaa gtagatgaat
    12181 acctagatca ctaacttgat gataatctat caaaacagga aggaaaattg tcaagattaa
    12241 aatacagaaa ataatgaaac atattttctt tgcttttgac atatacaatc ctttcgattt
    12301 aacatttaaa ctatttttcc cgtcattgat ttaaaaatag tttgctaact ttactggcga
    12361 aaagtttact ttctacctgt aaagaatgac actacagtaa tcacaatcgc tgcacctaca
    12421 atagatggga gcaaagccat tccagcgatt gctggacccc aactacctaa aagagattgt
    12481 cctgcatatg ccccgactaa accagcgaat acatttgcga tgattcccat agaactactt
    12541 ttttagtgat tttacctgcc aagagaccaa taagacctcc agcaataatt gatcacaaca
    12601 ctgcctaccc tcctttttta ttttaatatc aaaaaatcaa tttctttgat tattactatt
    12661 atataacttt aatatagaaa agtcaattat ttcgattgtt attattatat aattttaaaa
    12721 aatcaaattc tttaattgtt gctattatat aatttttaaa attaaaaata taatctttag
    12781 acttgaattt gattctgtat tcacgccctc aatagacggt aaaataagaa aattgtttat
    12841 atattgtctc cgtagtgtta ttatacgaaa taaaagattt taggaaaagt cgttatatca
    12901 tgctatacct attctttgtg gtataattgc aagaggttta atccgataat ttataaagag
    12961 agaaagatat tcatgagaga tttattatct aaaaaaagtc ataggcaatt agaattatta
    13021 gaattattat ttgaacataa acgttggttt catcgttctg aactagcaga gttattaaat
    13081 tgtacagaac gtgcagtcaa agatgatcta tcccatgtta aatctgcttt tcctgacttg
    13141 atttttcatt cttctactaa tggtatacgc attattaata ccgatgatag tgatattgaa
    13201 atggtttacc atcatttctt taaacattca actcattttt cgattttaga attcatcttc
    13261 tttaatgaag gttgtcaagc tgagagtatt tgtaaagaat tttatatcag ttcatcttcg
    13321 ctctatcgta ttattagcca aatcaataaa gtgattaaaa ggcaatttca atttgaagtt
    13381 agtctgaccc ctgttcaaat cattggaaat gagagagaca ttcgttactt ttttgcacaa
    13441 tatttttcag aaaaatatta tttcctagaa tggccatttg aaaatttttc atcagagcca
    13501 ctatctcaat tgttagaatt ggtttataag gaaacaagct ttccaatgaa tttgtcaacg
    13561 catagaatgc taaagttgct cctagttacg aacctatata gaataaagtt tggtcatttt
    13621 atggaagtag ataaagattc ttttaacgac caaagtttgg attttttaat gcaggcagaa
    13681 ggaatagaag gtgttgctca gagttttgaa tcagaataca atatctcttt agatgaagaa
    13741 gttgtttgcc aattatttgt gtcttacttt caaaaaatgt ttttcataga tgaaagtctc
    13801 tttatgaaat gcgtaaaaaa ggatagttat gttgaaaaat cttaccatct attgagtgat
    13861 tttattgatc agatttcagt caagtatcag attgaaatgg agaataagga taatctgatt
    13921 tggcatctgc ataataccgc acatctgtat cgtcaagagt tgtttactga gtttatttta
    13981 tttgatcaaa aagggaatac aatcaggaac tttcaaaata tttttccaaa atttgtttca
    14041 gatataaaaa aagagctttc tcactattta gagactcttg aggtttgttc tagttcaatg
    14101 atggtaaatc atctatctta taccttcatc actcatacca aacatttggt gattaatttg
    14161 ctacaaaatc agcctaaact aaaggtttta gttatgagta attttgatca gtatcatgca
    14221 aaattcgttg cagagacact ttcttattat tgtagcaata attttgaact ggaagtttgg
    14281 actgaattag aattatcaaa ggaatcttta gaagattcac cttatgatat cattatttct
    14341 aattttatta ttcctcctat tgaaaataag agactcatct attcaaataa tataaacacg
    14401 gtctcactca tatacttgtt aaatgccatg atgtttattc gattagatga gtaaccaaaa
    14461 ataacaaaaa aacgctattt cgcgtttgaa ctgtacctca aaagttagac agaaaaagtc
    14521 taattttggg ggtgtttttg ttaagaaaag accttcaatc atttaagcaa aatgtacatc
    14581 tagatttata gccatctaaa actcttgctt tttttataga agatacgaaa aaagccatga
    14641 aaccaaggct tttcctgttt tatgtagatg tttacacatg aaaattgaag tattttcaaa
    14701 agctaattgg agtgatttta ttcatgatgg gataaatgat ctggccaaaa atgattgaga
    14761 aatagttgct taaaaagcat ttgcatgata ctatatattg aaaggaggtg ataatatggt
    14821 agaacaaaga aaatcaatta ccatgaaaga tgttgcttta gaagcaggag ttagtgttgg
    14881 aactgtttca cgtgtaatta ataaagaaaa aggcattaaa gaagtaactt tgaaaaaagt
    14941 ggaacaagcg attaaaactt tgaattacat tccagattac tacgctagag gaatgaaaaa
    15001 aaatcgaaca gaaacgattg caatcattgt accaagtatc tggcatccct tcttttcaga
    15061 atttgctatg catgtggaaa atgaagtcta taagagaaat aacaaattac tcttatgttc
    15121 tatcaatggt acaaatagag agcaagacta tctggagatg ttgcgtcata ataaagttga
    15181 tggagtggtt gccattacct atagtccaat tgaacattac ttgacgtcag gaattccctt
    15241 tgttagtatt gaccgcacat actcagatat tgccattcct tgtgtttcat cagataatga
    15301 tgcaggtgga agagaagcag ctaaacaatt aattagtaaa ggatgtcagc atttagcctt
    15361 tgtgggcgga cataatacaa ccattaatga aaccaaacgt cgtagaattt catttgaaaa
    15421 gtatgtccaa gagcataaaa tacctcttag tatttttgat ttggatgaga cagttactga
    15481 ctattatgga aagctagaga gtttcttgga agaaaattct tctatagatg gaatttttac
    15541 aatcaacgat tttacagctt tggatgtgat tgaaatacta gaaaaaaatg gcaaacgtat
    15601 tcctcatgat gtccaaatta ttggatacga tggaattaaa atggctggag atagagatta
    15661 tctactttca actattgaac aaccattgga agaaatggca aaagaagcgg ttcgtatttt
    15721 gtttgatata attgatggaa agactgttaa tttgcagaca atcctaccag taaaatttgt
    15781 tgaaggaaaa acaacaaaaa atgaaaataa gtcttgacag aaagcgctat caatgataga
    15841 atgaattcag ataaaaagat ttatttttaa aacaaaaatg aaacgtttca aaaaaagaaa
    15901 taaagagaca gcgccaagcg ctatcttttc tagaaaaaaa tgaaacgttt caaaaaagga
    15961 ggttgctatg aatagcaaag cgaagcaagt ttctctttgg gaaagaatca agaaacaaaa
    16021 actcttgtta ttgatgactg tccccggttt agttttaacc tttatcttta aatacatccc
    16081 tatgtatggg gttttaatcg catttaaaga ttacaatcct ttaaaaggaa ttttagggag
    16141 tgattggatt ggtttttctg agtttacaaa attcatatcc tctcccaact ttggtatctt
    16201 gttagccaac acattaaaat taagtatcta tggtttattg cttggctttt taccaccaat
    16261 cattctcgcg attatgctca atcaactctt gagtgaaaaa gtcaaaaaac gaattcagct
    16321 cattttatac gcaccaaact ttatctcagt cgttgttatt gtcggtatga ttttcctctt
    16381 cttttcagtg ggaggaccaa tcaacaattt tctttctatg tttggaatga aggctgactt
    16441 cttgacaaat ccagacttct ttagaccttt atacatcttt agtggtatct ggcaaggaat
    16501 gggctgggct tcaacgctct acacggcaac attggtaaat gtagatccag ccttagtaga
    16561 agcagcccga ctggatggag ccaatatctt ccaacgaatc tggcacattg atattccagc
    16621 tcttaagcct attatggtta tccaatttgt tttagctgca ggtggaatta tgaatgtcgg
    16681 atatgaaaaa gcattcttga tgcagacatc gttaaatttg ccaacttctg aaattatctc
    16741 gacatatgtc tataaagttg gtcttgtatc aggagactat tcttactcaa cagcggttgg
    16801 tttgtttaat gcagtgatta acgtagtatt gcttgttgca gttaaccaaa tcgttaaacg
    16861 catgaataat ggtgaaggaa tttaaggagg aaagtatgaa aaattcgatt atggatacaa
    16921 aatttgatag acgtatctta ctcttaaata aaatcattat tgtctttatc gttttgatga
    16981 ctttgcttcc tttactttat atcgtcgtag catcctttat ggatcctaag gttctggtta
    17041 gtagagggat tagctttaat ccagccgatt ggactgtaga aggttaccag cgtgtattca
    17101 gtgaccaatc tattctaaga ggttttatca attctctact atactctttt ggatttgcag
    17161 ctttaacagt cttgctatct gtgtttacag cttatcctct ttctaagaaa gacttggttg
    17221 gacgtcgttg gattaactac ttcttgattg taactatgtt ctttggtggt ggtttagtcc
    17281 caacttactt gctcgtaaaa gaattgggaa tgctcaatac tccatgggct atcattgttc
    17341 caggtgctgt taacgtttgg aatattattc ttgctagggc ctatttccaa ggattgcctg
    17401 aagaattagt tgaagctgct gtcattgatg gtgcaaatga tttacagatt ttcttcaaaa
    17461 tcatgcttcc tcttgcaaaa ccaattatgt ttgttctctt cctttatgct tttgtaggac
    17521 agtggaactc atactttgat gcaatgattt atatcaagga tccaaacttg gaaccattgc
    17581 aacttgtact tcgtaaaatt ctcattcaga gccaaccagg tcaagacatg attggagcac
    17641 aagcggctat gaatgaaatg aaacgtttag ctgaattgat taaatacgca actattgtca
    17701 tttccagctt gccattgatt gttatgtatc cattcttcca aaaatacttt gataaaggaa
    17761 ttatggctgg ttcacttaaa ggataaaaaa agaaaaaata aaaggagttt tctcatgaaa
    17821 ttcaaaacat tctcaaaatc agcagttttg ttgacagcta gtttagcagt acttgcagcc
    17881 tgtggctcaa aaaatacagc ttcaagtcca gattataagt tggaaggtgt aacattcccg
    17941 cttcaagaaa agaaaacatt gaagtttatg acagccagtt caccgttatc tcctaaagac
    18001 ccaaatgaaa agttaatttt gcaacgtttg gagaaggaaa ctggcgttca tattgactgg
    18061 accaactacc aatccgactt tgcagaaaaa cgtaacttgg atatttctag tggtgattta
    18121 ccagatgcta tccacaacga cggagcttca gatgtggact tgatgaactg ggctaaaaaa
    18181 ggtgttatta ttccagttga agatttgatt gataaataca tgccaaatct taagaaaatt
    18241 ttggatgaga aaccagagta caaggccttg atgacagcac ctgatgggca catttactca
    18301 tttccatgga ttgaagagct tggagatggt aaagagtcta ttcacagtgt caacgatatg
    18361 gcttggatta acaaagattg gcttaagaaa cttggtcttg aaatgccaaa aactactgat
    18421 gatttgatta aagtcctaga agctttcaaa aacggggatc caaatggaaa tggagaggct
    18481 gatgaaattc cattttcatt tattagtggt aacggaaacg aagattttaa attcctattt
    18541 gctgcatttg gtatagggga taacgatgat catttagtag taggaaatga tggcaaagtt
    18601 gacttcacag cagataacga taactataaa gaaggtgtca aatttatccg tcaattgcaa
    18661 gaaaaaggcc tgattgataa agaagctttc gaacatgatt ggaatagtta cattgctaaa
    18721 ggtcatgatc agaaatttgg tgtttacttt acatgggata agaataatgt tactggaagt
    18781 aacgaaagtt atgatgtttt accagtactt gctggaccaa gtggtcaaaa acacgtagct
    18841 cgtacaaacg gtatgggatt tgcacgtgac aagatggtta ttaccagtgt aaacaaaaac
    18901 ctagaattga cagctaaatg gattgatgca caatacgctc cactccaatc tgtgcaaaat
    18961 aactggggaa cttacggaga tgacaaacaa caaaacatct ttgaattgga tcaagcgtca
    19021 aatagtctaa aacacttacc actaaacgga actgcaccag cagaacttcg tcaaaagact
    19081 gaagtaggag gaccactagc tatcctagat tcatactatg gtaaagtaac aaccatgcct
    19141 gatgatgcca aatggcgttt ggatcttatc aaagaatatt atgttcctta catgagcaat
    19201 gtcaataact atccaagagt ctttatgaca caggaagatt tggacaagat tgcccatatc
    19261 gaagcagata tgaatgacta tatctaccgt aaacgtgctg aatggattgt aaatggcaat
    19321 attgatactg agtgggatga ttacaagaaa gaacttgaaa aatacggact ttctgattac
    19381 ctcgctatta aacaaaaata ctacgaccaa taccaagcaa acaaaaacta gaggttgatt
    19441 atgggagata agaaatacac agtagaaaaa gccaatcgtt ttatagcaga aaataaacat
    19501 ctcgttaata ctcaatataa gcctgaagaa catttttcag ctgagattgg ttggatcaat
    19561 gatccaaatg gatttgtcta ttttcgtgga gaataccatc tcttttatca attctatcca
    19621 tatgatagtg tttgggggcc tatgcactgg ggacatgcta aaagtaagga cttggtgact
    19681 tgggagcact tgccagtggc acttgctcct gaccaagatt atgaccgaaa tggttgtttc
    19741 tcaggctctg ccattgtcaa ggatgatcgc ctctggctca tgtacactgg acatatcgaa
    19801 gaagaaaccg gtgtccgcca agtgcaaaat atggtatttt cagatgacgg gattcacttt
    19861 gaaaagattt cccaaaatcc agttgcaact ggatcagact taccagatga gttgattgct
    19921 gctgatttcc gtgatccaaa actctttgaa aaagatggac gctattactc cgtagtagct
    19981 gccaaacaca aggataatgt gggctgtatc gttctactag ggtccgataa cctagtagaa
    20041 tggcagttcg aatccatctt tttaaaaggg ggagaacacc aaggttttat gtgggaatgc
    20101 ccagattact tcgagttaga tgggaaagat tgccttatta tgtcacccat gcgttatcag
    20161 cgtgagggag actcatatca taacatcaac tcatcgcttt tgttcacggg taaggtagat
    20221 tggagagaaa aacgttttat cccagaatca gttcaagaaa ttgatcatgg ccaagacttc
    20281 tatgcgcctc aaacattgtt ggacgatcaa aatcgtcgta tcctgattgc ttggatgcag
    20341 acatgggggc gtacccttcc aacccatgac caagaacaca agtgggcatg tgccatgact
    20401 ctacctagaa ttctaagatt ggaagatggc aaactaagac aattccctgt taaaaaaggc
    20461 caatatcaaa tccaaataga taaagattgt cattaccact taggaaatga tatagattat
    20521 cttgaatttg gttatgacag taatgcgcag caagtttaca ttgatcgtag ccatcttatt
    20581 caaaaaattc taggtgaaga agaacaggac actagtcgac ggtatgtaga tattgaagct
    20641 aaagaattgg aagttgttct agataaaaat tccatcgaga tttttgtcaa tcaaggtgaa
    20701 gcaagcttga ctgcaactta ttacttaacg gtgccagctg agctatcacg aattgattaa
    20761 aaattaagtt atttctccta aagaaaaagt tctctttcta aaatagtgga aagaggactt
    20821 tttgtgtttt gggtatataa gcttagttta tggtatttgt aaaattggtg ttggattatg
    20881 atttaagcta gttttctaaa gaatttgaaa aaaattttat ttaagcaaaa aaaccttggt
    20941 tccaaggctt ttcctgttgt atttagatgc cccctacagg gattgtagga gatatgttgc
    21001 ttagatgttc ttgattttct ggtgttttgt aacgtttaaa tgagtttttt gagtttgttg
    21061 gtggggcgtt gcccggcaat tgcccgactt attgcttgaa aaagaattta aaatatagta
    21121 tagttaatta tagattaaca cttgcttgga ggaactgatg aagaacaatg aaagattagg
    21181 tattaaatta agtagagata gcgttttagg attgagggaa gttagaaggc tttatttagg
    21241 cagttcagat atcccagttt ctgatggcta tgtgattgaa gttgcttata accagatatc
    21301 acatgagatt gatattattg attgggtaga gttgaacaag tcaaaaatta agataagtga
    21361 aattagtgaa agcgtggata tagatgccac tagcttgaga acaactttga ctttagacac
    21421 attagtatat gaaggtatga gagatataca gttaaagttg agagagctta caaaggggag
    21481 agtattcttt tcatttgtag tgaagttagt tttgtttgct tctattttaa agaaaaaaga
    21541 tttactagaa aaatttcaag aaaagtgtta atcaagtatt gacactttat ctggatttcg
    21601 gtataatatg cttagaaagg aatctttcta aatttttttc gtccttatgt gttaatcaaa
    21661 gacgaataca aaaacatatt tttttactct aaaaagtgtt aatcaatgat gtatttgtta
    21721 gagaggtaga taaatggaat tgagagcacc accagttata atagtataaa acgtataata
    21781 aaaatatttt aacttgaatt atagaaaagg agaaacaaat catgaaacaa aaacaaccga
    21841 ttgtttctag aacgaaacaa catacatttg aagagcttat tcaagaccaa aagttagaaa
    21901 gattggctaa gttgtcgccc gatttggttg gaaggtatgg ttttactgct agctgtgcgt
    21961 cttcatttgc gaacttgatt aaagaagcgt atgggggtaa aaatctaaac gtagtttatg
    22021 cgagtcggat gttggctctc tggaatattg cttgcagttg ttatcataag gctgatgggt
    22081 attctttagc agatgcgctt tttagtgata aaaaaatttg tctagattct tactattacc
    22141 acaagaatac ctctaatacc ataactagtg atgtgataaa agatgtttac gataattata
    22201 ataattatat ggttttaact cgagaagcga cacctgaata catttatgtt gtacaaactg
    22261 aaatgccaaa agattcagat ttatattttt atattagaga agttctggga ttatcgttta
    22321 gtaccatgca ttatgcattt ttagtcaagg ttcttgcagg agcgcttgct agaaaatata
    22381 agccatatcg aaattgaatt atttaaattt atactcttcg aaaatcaaat tcaaaccacg
    22441 tcagcttcgc cttgctgtac tcaagtgctg tctgtggcta gcttcttagt ttgctttttg
    22501 attttcattg agtattactc ttatggtagt tatttatggc ataataatat tgatttggga
    22561 gttatagcga aaattttagg ttctataata tttgtagtgg gtaaatccac tatagatatt
    22621 atggagccta tttt
//
LOCUS       DAVFER010000034        22282 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1105170250
            SAMEA2167659-rid19724873.denovo.034, whole genome shotgun sequence.
ACCESSION   DAVFER010000034 DAVFER010000000
VERSION     DAVFER010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2167659
            Sequence Read Archive: ERR388902
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 22282)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22282)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928716.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928716.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 04:07:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,118
            CDSs (total)                      :: 2,073
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 120
            CDSs (without protein)            :: 120
            Pseudo Genes (ambiguous residues) :: 0 of 120
            Pseudo Genes (frameshifted)       :: 67 of 120
            Pseudo Genes (incomplete)         :: 47 of 120
            Pseudo Genes (internal stop)      :: 34 of 120
            Pseudo Genes (multiple problems)  :: 23 of 120
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22282
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2167659-rid19724873.denovo.034"
                     /strain="1105170250"
                     /db_xref="taxon:1313"
     gene            635..1018
                     /locus_tag="VU534_001422"
     CDS             635..1018
                     /locus_tag="VU534_001422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="immunity protein"
                     /protein_id="HEU1513998.1"
                     /translation="MKYRLFFVIFLSSVLDILLGTFLQISIVSIGWLVLYSGLFEAGV
                     FLLANKGVAVKIKEVDIRNRFKFIFGKTLWFQILLLIFLIIKLYLGLDARLILFYGHI
                     FIVFNALMYLLSSSQVSLKKNKLSS"
     gene            1070..1759
                     /locus_tag="VU534_001423"
     CDS             1070..1759
                     /locus_tag="VU534_001423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000760553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU1513999.1"
                     /translation="MKKYQLLFKISAVFSYLFFVFSLSQLTLIVQNYWQFSSQIGNLF
                     WIQNILSLLFIGVMIVVLVKTGHGYLFRIPRKKWLWYSILTVLVLVFQISFNVQTAKH
                     VQSTAEGWAVLIGYSGTNFAELGIYIALFFLVPLMEELIYRGLLQHAFFKHSRFGLDL
                     LLPSILFALPHFSSLPSLLDIFVFATVGIIFAGLTRYTKSIYPSYAVHVINNIVATFP
                     FLLTFLHRVLG"
     gene            1801..2034
                     /locus_tag="VU534_001424"
     CDS             1801..2034
                     /locus_tag="VU534_001424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1514000.1"
                     /translation="MYKHLFFLDSKTLDRLTPYILVLASDTIAFNVFVLTFVSAVVFN
                     FLNSMLALMAIFIGAGYVVGFWLLILNENQRAN"
     gene            2185..2796
                     /locus_tag="VU534_001425"
     CDS             2185..2796
                     /locus_tag="VU534_001425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000394041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU1514001.1"
                     /translation="MEFFDKFHALCFGFLVLIIVITVPYTINHGGFFQNESALILVSL
                     LVTSLSVAYARKFEMISFGMLSKKQLLLFIAIFLLSVLETLVYIHFFAVSSGSGVQHL
                     AEVSRGISLSLILTTSVFGPIQEELIFRGLLQGAVFDNSWLGLVLTSSLFSFMHGPSN
                     VPSFIFYLLGGLLLGFAYKKSQNLWVSTLVHMLYNSWPLLYYL"
     gene            2957..3751
                     /locus_tag="VU534_001426"
     CDS             2957..3751
                     /locus_tag="VU534_001426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000363010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase family protein"
                     /protein_id="HEU1514002.1"
                     /translation="MDLGDNELTLTPIPGKSGKAYMGSYPDGKRIFVKMNTSPILPGL
                     AREQIAPQLLWSRRLADGRDMCAQEWLTGKILTPYDMNRKQIVNILTRLHRSRPLMTQ
                     LSRLGYAMETPVDLLQSWQETAPDALRKNHFISEVMADLRQTIPGFREDHATIVHGDV
                     RHSNWIETDSGLIYLVDWDSVRLTDRMFDVAHMLCHYISEHQWKEWLTYYGYKYNQTV
                     LSKLYWYGQLSYLSQISKYYMNQDLENVNREIHGLRHFRDKYGKRR"
     gene            3748..4383
                     /gene="trmB"
                     /locus_tag="VU534_001427"
     CDS             3748..4383
                     /gene="trmB"
                     /locus_tag="VU534_001427"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001266107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HEU1514003.1"
                     /translation="MRVRNRKGATELLEANPQYVVLNPLEAKAKWRDLFGNDNPIHVE
                     VGSGKGAFVSGMAKQNPDINYIGIDIQKSVLSYALDKVLEVGVPNIKLLWVDGSDLTD
                     YFEDGEIDRLYLNFSDPWPKKRHEKRRLTYKTFLDTFKRILPENGEIHFKTDNRGLFE
                     YSLVSFSQYGMKLNGVWLDLHASDFEGNVMTEYEQKFSNKGQVIYRVEAEF"
     gene            4509..4988
                     /gene="rimP"
                     /locus_tag="VU534_001428"
     CDS             4509..4988
                     /gene="rimP"
                     /locus_tag="VU534_001428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000338698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HEU1514004.1"
                     /translation="MDAIATIVELVREVVEPVIEAPFELVDIEYGKIGSDMILSIFVD
                     KPEGITLNDTADLTEIISPVLDTIKPDPFPEQYFLEITSPGLERPLKTKDAVAGAVGK
                     YIHVGLYQAIDKQKVFEGTLLAFEEDELTMEYMDKTRKKTVQIPYSLVSKARLAVKL"
     gene            5032..6168
                     /gene="nusA"
                     /locus_tag="VU534_001429"
     CDS             5032..6168
                     /gene="nusA"
                     /locus_tag="VU534_001429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusA"
                     /protein_id="HEU1514005.1"
                     /translation="MSKEMLEAFRILEEDKGIKKEDIIDAVVESLRSAYRRRYGQSDS
                     VAIDFNEKTGDFTVYTVREVVDEVFDSRLEISLKDALAINSAYELGDKIKFEEAPAEF
                     GRVAAQSAKQTIMEKMRKQTRAITYNTYKEHEQEIMSGTVERFDNRFIYVNLGSIEAQ
                     LSKQDQIPGEVFASHDRIEVYVYKVEDNPRGVNVFVSRSHPEMIKRLMEQEIPEVYDG
                     TVEIMSVAREAGDRTKVAVRSHNPNVDAIGTIVGRGGANIKKITSKFHPARYDAKNDR
                     MVPIEENIDVIEWVADPAEFIYNAIAPAEVDQVIFDENDSKRALVVVPDNKLSLAIGR
                     RGQNVRLAAHLTGYRIDIKSASEFEAMEDAASVELEVENDTVEE"
     gene            6190..6483
                     /locus_tag="VU534_001430"
     CDS             6190..6483
                     /locus_tag="VU534_001430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000857559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HEU1514006.1"
                     /translation="MKTRKIPLRKSVVSNEVIDKRDLLRIVKNKEGQVFIDPTGKANG
                     RGAYIKLDNAEALEAKKKKVFNRSFSMEVEESFYDELIAYVDHKVKRRELGLE"
     gene            6476..6775
                     /locus_tag="VU534_001431"
     CDS             6476..6775
                     /locus_tag="VU534_001431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxQ-related RNA-binding protein"
                     /protein_id="HEU1514007.1"
                     /translation="MNKQKISNLLGLAQRAGRIISGEELVVKAIQDGKAKLVFLAHDA
                     GPNLTKKIQDKSHYYQVEIVTVFSTLELSIAVGKSRKVLAVTDAGFTKKMRSLME"
     gene            6792..9668
                     /gene="infB"
                     /locus_tag="VU534_001432"
     CDS             6792..9668
                     /gene="infB"
                     /locus_tag="VU534_001432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HEU1514008.1"
                     /translation="MSKKRLYEIAKELGKESKEVVARAKELGLDVKSHSSSVEEAVAA
                     KIAASFKPAAAPKVEAKPAAPKVSAEKKAEKSEPAKPAVAKEEAKPAAPKASAEKKAE
                     KSEPVKPAVAKEEAKPAEPVTPKTEKVAAKPQSRNFKAEREARAKEQAERRKQNKGNN
                     RDQQQNGNRQKNDGRNGGKQGQSNRDNRRFNDQAKKQQGQQKRRNERRQQEDKRSNQA
                     APRIDFKARAAALKAEQNAEYARSSEERFKQYQAAKEALAQANKRKEPEEIFEEAAKL
                     AEQAQQVQAVVEVVPEKKEPAVDTRRKKQARPDKNRDDYDHEEDGPRKQQKNRSSQNQ
                     VRNQKNSNWNNNKKNKKGNNKNNRNQTPKPVTERKFHELPTEFEYTDGMTVAEIAKRI
                     KREPAEIVKKLFMMGVMATQNQSLDGETIELLMVDYGIEAKQKVEVDNADIERFFVED
                     GYLNEDELVERPPVVTIMGHVDHGKTTLLDTLRNSRVATGEAGGITQHIGAYQIVENG
                     KKITFLDTPGHAAFTSMRARGASVTDITILVVAADDGVMPQTIEAINHSKAANVPIIV
                     AINKIDKPGANPERVIGELAEHGVMSTAWGGDSEFVEISAKFNQNIEELLETVLLVAE
                     IQELKADPTVRAIGTVIEARLDKGKGAVATLLVQQGTLNVQDPIVVGNTFGRVRAMTN
                     DLGRRVKVAGPSTPVSITGLNEAPMAGDHFAVYEDEKSARAAGEERAKRALMKQRQAT
                     QRVSLENLFDTLKAGELKSVNVIIKADVQGSVEALSASLQKIDVEGVKVTIVHSAVGA
                     INESDVTLAEASNAFIVGFNVRPTPQARQQAEADDVEIRLHSIIYKVIEEMEEAMKGM
                     LDPEFEEKVIGEAVIRETFKVSKVGTIGGFMVINGKVARDSKVRVIRDGVVIYDGELA
                     SLKHYKDDVKEVTNGREGGLMIDGYNDIKMDDVIEAYVMEEIKR"
     gene            9919..10269
                     /gene="rbfA"
                     /locus_tag="VU534_001433"
     CDS             9919..10269
                     /gene="rbfA"
                     /locus_tag="VU534_001433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HEU1514009.1"
                     /translation="MANHFRTDRVGMEIKREVNEILQKKVRDPRVQGVTIIDVQMLGD
                     LSVAKVYYTILSNLASDNQKAQIGLEKATGTIKRELGRNLKLYKIPDLTFVKDESIEY
                     GNKIDEMLRNLDKN"
     gene            10548..11327
                     /locus_tag="VU534_001434"
     CDS             10548..11327
                     /locus_tag="VU534_001434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1514010.1"
                     /translation="MAEQDLAMQVLQQVVKLPVVKVDRSKFLVDKFSKELDPKDIPTL
                     LEQGPTTLLSQEILDRVANACIRDNVLLASGTSVLAGLPGGLAMAITIPADVAQFYAF
                     SLKLAQELGYIYGYEDLWASREELSEDAQNTLLLYLGVMLGVNGTAALLRVGSITIAK
                     QVMKIVPNKALTKTLWYPILKKVLKIFGVNLTKGGLAKGMGKFIPILGGIISGGLTFA
                     TMKPMGESLQKELSKLVNYSEVQYQEDVETIRKEAEIIKGE"
     gene            11329..11511
                     /locus_tag="VU534_001435"
     CDS             11329..11511
                     /locus_tag="VU534_001435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001068155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1514011.1"
                     /translation="MNPIKAFAKIYGNYFLTVQGVKVMKTIKKADHVVVGLGKLFIAD
                     KLMDTARWLIKPEERE"
     gene            11971..12204
                     /locus_tag="VU534_001436"
     CDS             11971..12204
                     /locus_tag="VU534_001436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006144975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1858 domain-containing protein"
                     /protein_id="HEU1514012.1"
                     /translation="MDNIIDVSIPVAEVVDKHPEVLEILVELGFKPLANPLMRNTVGR
                     KVSLKQGSKLAGTPMDKIVRTLEANGYEVIGLD"
     gene            12204..13538
                     /locus_tag="VU534_001437"
     CDS             12204..13538
                     /locus_tag="VU534_001437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000752887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF438 domain-containing protein"
                     /protein_id="HEU1514013.1"
                     /translation="MTDERIHILRDILLELHNGASPESVQDRFDATFTGVSAIEISLM
                     EHELMNSDSGVTFEDVMELCDVHANLFKNAIKGVEVSDTEHPGHPVRVFKEENLALRA
                     ALIRIRRLLDTYESMEDEEMLAEMRKGLVRQMGLVGQFDIHYQRKEELFFPIMERYGH
                     DSPPKVMWGVDDQIRELFQTALTTAKSLPEVSISSVKEAFEAFATEFESMIFKEESIL
                     LMILLESFTQDDWLQIAEESDAYGYAIIRPSEKWVPERQSFIEEKIAEEPVQLDTAEG
                     QVQQVIDTPEGHFTITFTPKEKEAVLDRHSQQAFGNGYLSVEQANLILNHLPMEITFV
                     NKEDIFQYYNDNTPADEMIFKRTPSQVGRNVELCHPPKYLDKVKTIMKGLREGSKDKY
                     EMWFKSESRGKFVHITYAAVHDEDGEFQGVLEYVQDIQPYREIDTDYFRGLE"
     gene            13548..13802
                     /locus_tag="VU534_001438"
     CDS             13548..13802
                     /locus_tag="VU534_001438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000119704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1912 family protein"
                     /protein_id="HEU1514014.1"
                     /translation="MSYEQEFMKEFEAWVNTQIMINDMAHKESQKVYEEDQDERAKDA
                     MIRYESRLDAYQFLLGKFENFKVGKGFHDLPEGLFGERNY"
     gene            13898..14293
                     /locus_tag="VU534_001439"
     CDS             13898..14293
                     /locus_tag="VU534_001439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
                     /protein_id="HEU1514015.1"
                     /translation="MSKKLNRKKQLRNGLRRAGAFSSTVTKVVDETKKVVKRAEQSAS
                     AAGKAVSKKVEQAVEATKEQAQKVANSVEDFAANLGGLPLDRAKTFYDEGIKSASDFK
                     NWTEKELLALKGIGPATIKKLKENGIKFK"
     gene            14706..15155
                     /locus_tag="VU534_001440"
     CDS             14706..15155
                     /locus_tag="VU534_001440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase"
                     /protein_id="HEU1514016.1"
                     /translation="MIGVVARENAAEQIKQYQKFTVNISDETSMLAMEQAGFISHQEK
                     LERLGVHYEISERTQTPILDACPLVLDCRVDRIVEEDGICHIFAKILERLVAPELLDE
                     KGHFKNQLFAPTYFMGDGYQRVYRYLDKRVDMKGSFIKKARKKDGKN"
     gene            15142..15702
                     /locus_tag="VU534_001441"
     CDS             15142..15702
                     /locus_tag="VU534_001441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000124561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU1514017.1"
                     /translation="MARTELPDKIETERLVLRVRTVVDAEDIHTYASLPEVAYPAGFP
                     PVKILEDEIYYLEHILPERTQKENLPAGYGIVVKGTDKVIGSVDFNHLHADDVLELGY
                     TLHPDYWGRGYVPEAACSLIDLAFKELGLHKIELTCFGYNLQSQRVSEKLGFTLEARI
                     RDRKDAQGNCCDDLRYGLLRSEWEVI"
     gene            15702..16280
                     /locus_tag="VU534_001442"
     CDS             15702..16280
                     /locus_tag="VU534_001442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000550018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEU1514018.1"
                     /translation="MHLFIIGAPASGKMTIGQELSRLTDATLFYNHQAIDFALEIYQD
                     YTEEMWEFVRGITFSFLGASARNQRSVILTDVIDFSNQYQLMYLKQIQDLLDNFHQEI
                     LFVELETSLEECIRRNRTENRLKHKPLKRHIEVSEREILETAETLQLNSQHQPNELHH
                     YFKINNTNLSAEEAAKQIQNKINKIEKGHTHV"
     gene            16273..18924
                     /locus_tag="VU534_001443"
     CDS             16273..18924
                     /locus_tag="VU534_001443"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009732359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HEU1514019.1"
                     /translation="MSKELSPKYNPAEVEAGRYQKWLDADVFKPSGDQKAKPYSIVIP
                     PPNVTGKLHLGHAWDTTLQDIIIRQKRMQGFDTLWLPGMDHAGIATQAKVEERLRGEG
                     ITRYDLGRESFLTKVWEWKDEYATTIKEQWGKMGLSVDYSRERFTLDEGLSKAVRKVF
                     VNLYKKGWIYRGEFIINWDPAARTALSDIEVIHKDVEGAFYHMNYMLEDGSRALEVAT
                     TRPETMFGDVAVAVNPEDPRYKDLIGKNVILPIANKLIPIVGDEHADPELGTGVVKIT
                     PAHDPNDFLVGQRHNLPQVNVMNDDGTMNELAFEFSGMDRFEARKAVVAKLEEIGALV
                     KIEKRVHSVGHSERTGVVVEPRLSTQWFVKMDQLAKNAIANQDTEDKVEFYPPRFNDT
                     FLQWMENVHDWVISRQLWWGHQIPAWYNADGEMYVGEEAPEGDGWTQDEDVLDTWFSS
                     ALWPFSTMGWPEVDSEDFKRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGRQPFQNVL
                     IHGLIRDEQGRKMSKSLGNGIDPMDVIEKYGADALRWFLSNGSAPGQDVRFSYEKMDA
                     SWNFINKIWNISRYILMNNEGLTLDVAHDNVTKVATGEAGNVTDRWILHNLNETIAKV
                     TENFDKFEFGVAGHILYNFIWEEFANWYVELTKEVLYSDNEDDKVITRSVLLYTLDKI
                     LRLLHPIMPFVTEEIFGQISEGSIVTAAYPTVNLAFEDLAAHTGVESLKDLIRAVRNA
                     RAEVNVAPSKPITILVKTSDSDLEAFFNSNVNYIKRFTNPEHLEIASTIPAPELAMSS
                     VITGAEIYLPLADLLNVEEELARLDKELAKWQKELDMVGKKLSNERFVANAKPEVVQK
                     ECDKQADYQAKYDATVARIDEMKKLVK"
     gene            19005..19169
                     /locus_tag="VU534_001444"
     CDS             19005..19169
                     /locus_tag="VU534_001444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000516551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA cytosine methyltransferase"
                     /protein_id="HEU1514020.1"
                     /translation="MGKIVAIDLFNGAGGTTSGLKKSGIDVQVAVEIDSVAVKTYKLN
                     NPEVSVIDME"
     gene            19220..20824
                     /locus_tag="VU534_001445"
     CDS             19220..20824
                     /locus_tag="VU534_001445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000006331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEU1514021.1"
                     /translation="MSEYWFSTNVDQIDEVDGKQCLIYSYYNIKASRNVEVLKGRSGT
                     KKGLDYWEPYAPQKQYEMERLPKNKYIGSSSTDRWDGIEKNVVFCDCKEYVSAFDLFF
                     YHYNFKKISTQRSKQDFIRLRSKPVADILKNNTSSYTRYKKEMVIDNVKVDDKVCEII
                     SEIMDESYTDIQILTHKLYSKGDDIKASKTIWMKKSGKEYSEAFAGTGEARIILLVND
                     IVNAQSNSLILIDEPEISLHPSAIYKFKEFLLQECLNKKHQIIITTHSTQLIKDFPRE
                     AVKLLVKNGEKVDVIENIDYQDAFFELGDVYHSRKMIYVEDRLAKYILEFVITHSGSE
                     NLKQNLVVRYIPGGANQIICNNILNSSYLDSDNHYFWLDGDQNTNVSESNNLMNYLEN
                     GVVISDKIPESDNKNLDDIIKLITGCPIKFNVSGNKGQKNNIELIAKQRSFIDYWAKY
                     VSYLPFPTPEFFLANLCNSVDREGYDFSKDGNGKEYFRKKTQVALGIENITSEDIFQE
                     QRRAVSKIQPESSMFQCIKEKLEALF"
     gene            21204..22007
                     /locus_tag="VU534_001446"
     CDS             21204..22007
                     /locus_tag="VU534_001446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic/DOC family protein"
                     /protein_id="HEU1514022.1"
                     /translation="MQPTYNIDNPNLSYEAKRDLWRIGFGLQKVDNLVPSAYMESLAE
                     KQSRGELTYEQVYEDATAYHHTIDASTEEADLVSLRIVELLSRRGFSFSPAILLAIHK
                     ELFQDIFEPSIPVGQFRQTNITKNEPVLNGESVVYSDYSMIQMTLDYDFNQEKQVAYA
                     TLTQADMVKKIQHFISGIWQIHPFREGNTRTVTVFLIQYLREFGFDIDNTPFQQHSKY
                     FRDALVLDNAKILQRRPEFLTAFFENLLLGGQNDLSSEKMYLDLDLDLS"
     gene            complement(22122..22282)
                     /locus_tag="VU534_001447"
                     /pseudo
     CDS             complement(22122..22282)
                     /locus_tag="VU534_001447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677188.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         6864 a         4019 c         4930 g         6469 t
ORIGIN      
        1 atgcttactt tttaaatttt ttaacaattc aagatgtttc gatgacaatt caagatttgg
       61 atgaaaaatt ttaaaaaaca atgatatact aaacttgtca aagttgcaac gggtgctgct
      121 acattatgtt aaaaatcgct cttgattgat aagctggatt tgttaggaaa ggagtaaata
      181 attatggata agaaaaagat agtttcgact ataatatgta tagtatttct tgtagtgtca
      241 gtagataatt tttttagaga cttaaccccg ttactgttca ttttaaatat tattggcctg
      301 tcttgctttt cagtgctaac atacattaaa ataaaagaga tactcttaaa tataagtaaa
      361 tgatgatttg gttagtccta gaaccaatca acttatgttt atcggcttgg cagattttat
      421 gtttgtcatt tgtttgtata gaggtatttc agaaacagaa ttctatcaac aactaatcgc
      481 ttatataggt gtattctctg cttgtttatc acgcttctgc tcatgtgggg cttgaagtat
      541 tataaaaagt agctttctat ccttttctga caggatattt gagtagaagg ctctattaaa
      601 ttgttagtga aataaatgaa tggaggtatt taatatgaaa tacagattat tttttgttat
      661 tttcttgagt agtgtgttgg atattctttt agggacattt ttacaaatct ctatcgtatc
      721 tattgggtgg cttgttcttt acagtggttt gtttgaagca ggagttttcc ttcttgctaa
      781 taaaggggtg gcggtaaaaa tcaaggaagt agatattcga aatcgcttta aatttatttt
      841 tggaaaaacc ttatggtttc aaattctttt gctcatcttt ttgataatca aactttatct
      901 tggtttggat gcgaggttga ttttattcta tggacatatt ttcattgtct ttaatgcctt
      961 aatgtatcta ttatctagta gtcaggttag ccttaaaaaa aacaaactgt cttcttaatc
     1021 ttacagcagt agagcctgac aaggtgaggt catagtaggg aggatttcta tgaaaaagta
     1081 tcaacttcta ttcaaaataa gtgcagtctt ctcttactta tttttcgtat ttagtctttc
     1141 tcagctgacg cttatcgtcc aaaactattg gcaattttct tctcagatag gcaatttatt
     1201 ctggattcaa aatatcttga gtttactttt tattggagtc atgattgtgg ttcttgttaa
     1261 gacaggccat ggttatctct tccgcattcc aagaaaaaaa tggctttggt attcgatttt
     1321 gacagtatta gtgctagtgt tccagatctc ttttaacgtt cagacagcta aacatgttca
     1381 gtcaactgcg gaaggttggg ctgtattgat tggttatagt gggactaact ttgcagagct
     1441 aggtatttat atagccctgt tctttctggt tccactgatg gaagaattga tttatagagg
     1501 attactgcaa catgctttct ttaagcattc gcgatttggt cttgatttgc ttcttccttc
     1561 tattttattt gctctccctc atttttcaag cctgcctagt ctgttagata tcttcgtctt
     1621 tgcaacagtt ggaatcatct ttgctggttt gacccgctat accaagagca tttatccatc
     1681 ctatgcggtg catgtgatca ataatattgt agcgaccttc ccgtttttgc tcacttttct
     1741 acatagggtc ttggggtaaa aaaacaaaag gcttgctttt cagccataga ggaggtcatc
     1801 atgtataaac acttattttt cctagattcc aaaactttag atcggttgac accctatatt
     1861 ctagtcttgg cttctgacac cattgctttt aatgtttttg tgctaacctt tgtatctgcg
     1921 gtggttttta atttcctaaa ttccatgcta gctttaatgg ctatattcat aggggctggc
     1981 tatgtggtcg gattttggtt actaatactc aatgaaaatc aaagagcaaa ctaggaaact
     2041 agccgcaggc tgtacttgag tacggcaagg cgacgttgac gtggtttgaa tttgattttc
     2101 gaagagtata aaatggtttg ttttggaaag gctagaacta aagaatgacg tgtaggaagt
     2161 ctgtttgttg aggaggataa ttttatggag ttttttgata aatttcatgc cttgtgtttt
     2221 ggatttttag tactaataat tgtcattaca gttccttata cgattaacca tgggggtttt
     2281 tttcaaaatg aatctgcatt gattcttgta agtcttcttg taacctcgct gagtgttgct
     2341 tatgctagaa agtttgaaat gatttctttt gggatgttaa gcaagaaaca acttttgctt
     2401 ttcattgcaa tctttcttct aagtgtactt gagacgctgg tttatattca tttcttcgct
     2461 gtttcttctg gctcaggggt ccaacacttg gcggaagtca gcagaggaat ttccctgtct
     2521 ttgattttga ctacctcagt ttttggcccc atccaggagg aactcatttt cagaggactt
     2581 cttcaaggtg cggtttttga caattcttgg ttagggcttg tgctaacttc ctctctcttt
     2641 tctttcatgc atggaccttc taatgtccct tcgtttattt tttatctact tgggggtttg
     2701 ttgctgggct ttgcttataa aaagagtcaa aacctatggg tttctactct agtccatatg
     2761 ctttacaaca gttggccact cttatattat ttataaaaat tatgaaaagg taagcagaag
     2821 acggtgctta cctttttcaa gctataatga tacccaagcc aatccagagg cttttctttg
     2881 agaatcgggt tagagtggtt gacgaatagg ccaaaaacta gtagaatagt aaggaaactt
     2941 tatacggagg aaagaaatgg atttgggtga taatgagcta acactgactc ccatacctgg
     3001 gaaaagtggc aaggcttata tgggtagcta tcctgatggg aagcgcatct ttgtaaaaat
     3061 gaacacctct ccaatcctac ctggtctagc tagagaacaa attgctccac aattattatg
     3121 gagtcgtcgt ttggcagatg ggcgtgatat gtgtgctcaa gaatggttga caggcaagat
     3181 attgaccccc tatgatatga atcgtaagca aatcgtcaat attttaaccc gtcttcatcg
     3241 ctcacgtccg ttgatgacac aattgagtcg tttgggctat gccatggaaa cacctgtaga
     3301 tttactacag tcttggcagg aaacggctcc agatgctttg cgtaaaaatc attttatcag
     3361 tgaagtgatg gctgatttac gtcagactat tccaggattt agagaggacc atgcgaccat
     3421 tgtccatgga gatgtacgac atagtaattg gattgagaca gatagtggct tgatttattt
     3481 agtagattgg gattcggttc gcttgaccga tcgcatgttt gatgtggccc atatgctctg
     3541 ccattatatt tcagaacatc agtggaagga atggttgacc tactacggtt acaagtacaa
     3601 tcaaacggta ttaagtaaat tgtattggta tggtcaattg tcttatttga gtcagatttc
     3661 caagtattat atgaaccaag atttagaaaa tgtcaatcgg gagattcatg gtttgcgtca
     3721 tttccgagac aagtatggaa agagaagatg agagttagaa atcgtaaagg ggcaacagaa
     3781 ttactagagg caaatcccca gtatgtggtc ctcaatccct tggaagccaa ggcaaaatgg
     3841 cgggacttgt ttggcaatga taatcccatt catgtggaag ttggaagtgg aaagggtgcc
     3901 tttgtttcag gtatggccaa gcaaaaccct gacatcaact atatcgggat tgatattcaa
     3961 aagtctgttt tgagctacgc tttggacaag gtgcttgaag ttggagtgcc taacatcaag
     4021 ctcttgtggg tagatggttc tgacttaact gactactttg aagacggtga gattgatcgc
     4081 ttgtatctga acttttcaga tccatggccg aaaaaacgcc atgaaaagcg tcgtttgacc
     4141 tacaagacct tcttggatac cttcaaacgt atcttgcctg aaaatggaga aattcatttc
     4201 aagacggata accgtggctt gtttgagtac agtttagtga gcttttctca atatggcatg
     4261 aaactcaatg gtgtctggtt agatttgcat gccagtgatt ttgaaggcaa tgtcatgaca
     4321 gaatacgagc aaaaattctc aaacaagggg caagttatct accgagttga ggcagaattt
     4381 taagagataa cctaaaatta ggctgtacaa gtgcttttgc tttacataag ttggcaaacg
     4441 tgctatactg atagtaagaa tatgaaaagt gaggcgggga aatatcttcg cctcttgctt
     4501 atgaggaggt ggacgcaatc gcaacaatcg tagaattagt cagagaagtt gtagaacctg
     4561 tcatagaagc tccttttgaa ctcgtggata tcgagtatgg aaagattggc agtgacatga
     4621 ttctcagtat ttttgtagat aaacccgaag gaattacctt gaacgacacg gcagacttga
     4681 cagaaattat cagtcctgtc ctagacacca tcaagccaga tcccttccca gaacaatatt
     4741 tcctagaaat taccagtcca ggtttggaac gtcctttgaa aaccaaggat gccgtcgctg
     4801 gagcggttgg aaaatacatc catgtcgggc tctaccaagc catcgataag caaaaggtct
     4861 ttgaaggaac cttgttggcc ttcgaagagg acgagttgac tatggaatat atggacaaga
     4921 cgcgtaagaa aaccgtccaa attccataca gtttagtatc aaaagcacgt ttagcagtta
     4981 aattatagaa aaagaaagga tagcttttga ggattcaaaa gtgaagaaaa catgagtaaa
     5041 gaaatgctag aggccttccg cattttggaa gaagacaagg gaatcaaaaa agaagatatc
     5101 atcgacgcag tagtagagtc gcttcgttcc gcttatcgca gacgctatgg tcagtcagac
     5161 agcgtagcta ttgacttcaa cgaaaaaaca ggtgacttta cagtttatac tgtccgtgaa
     5221 gttgttgatg aagtatttga tagccgtttg gaaatcagct tgaaagatgc tcttgccatt
     5281 aattcagctt atgaacttgg agacaaaatc aagtttgaag aagcaccagc tgagtttggt
     5341 cgtgtagcag cccaatctgc caaacaaacc atcatggaaa aaatgcgcaa gcaaacacgt
     5401 gccatcactt acaatactta caaagaacat gagcaagaaa tcatgtctgg tacagtagaa
     5461 cgctttgaca accgctttat ctatgtcaac cttggtagca tcgaagccca attgtcaaaa
     5521 caagaccaaa ttcctggaga agtttttgct tctcatgatc gtatcgaagt ttatgtttac
     5581 aaggttgaag acaaccctcg tggtgtgaac gtctttgtta gccgtagtca tccagaaatg
     5641 atcaaacgtt taatggagca agaaattcca gaagtttatg atggaactgt tgaaatcatg
     5701 agcgtggctc gtgaagcagg tgaccgtacg aaggttgctg ttcgtagcca caatccaaac
     5761 gtggatgcta tcggtacaat cgttggacgt ggtggtgcta atatcaagaa gattactagc
     5821 aaattccacc cagctcgtta cgatgctaaa aatgaccgca tggtaccaat cgaagaaaat
     5881 atcgatgtta tcgagtgggt agcagatcca gctgaattta tctacaatgc catcgctcct
     5941 gctgaggttg accaagttat ctttgatgaa aacgacagca aacgtgcctt ggtggttgtt
     6001 ccagataaca agctttctct tgccattggt cgtcgtggac aaaacgtgcg cttggcggct
     6061 cacttgactg gttaccgtat cgatatcaag tctgctagcg aatttgaagc catggaagac
     6121 gctgcttcag tagagttgga agtagaaaac gatactgtag aagaataaaa gctgctagag
     6181 gagggaaaga tgaaaacaag aaaaatccct ttgcgcaagt ctgttgtgtc taacgaagtg
     6241 attgataagc gtgatttgct ccgcattgtc aagaacaagg aaggacaagt ctttattgat
     6301 cctacgggca aggccaatgg ccgcggcgct tatatcaaac tagacaatgc agaagcccta
     6361 gaggcgaaaa agaagaaggt ctttaaccgc agctttagca tggaagtgga agaaagcttt
     6421 tatgacgagt tgatcgctta tgtggatcac aaagtgaaaa gaagagagtt gggacttgaa
     6481 taagcaaaag ataagtaatc tcttggggct tgctcagcga gcagggcgca tcatatcggg
     6541 tgaagaattg gtggtcaagg ccattcaaga cggcaaggcc aagttggtct ttctagctca
     6601 tgatgctgga cccaatctga ccaagaagat tcaagataaa agtcattatt atcaagtaga
     6661 aattgtaacc gtgttttcaa cactggaatt aagcatagca gtcgggaaat cgagaaaggt
     6721 tttggctgta acagatgctg gatttacaaa gaaaatgagg tctcttatgg aatagaagag
     6781 gaggacatga tttgtctaag aaaagattgt acgaaatcgc aaaagaactt ggaaaagaaa
     6841 gtaaagaagt tgtagcgcgt gcaaaagagt tgggcttgga tgtgaaaagt cactcatcaa
     6901 gtgtggaaga agctgtcgct gcaaaaattg ctgccagctt taagcctgca gctgctccga
     6961 aagtagaagc aaaacctgca gccccaaaag taagtgcaga aaagaaagcc gaaaaatctg
     7021 agccagctaa accagctgta gctaaggaag aggcaaaacc tgcagcccca aaagcaagtg
     7081 cagaaaagaa agccgaaaag tctgaaccag taaaaccagc tgtagccaag gaagaggcaa
     7141 aaccagctga gccagtcact ccgaaaacag aaaaagtagc ggctaaaccg caaagtcgta
     7201 atttcaaggc tgagcgtgaa gcacgtgcta aagagcaggc agagcgacgc aagcaaaata
     7261 agggcaataa ccgtgaccaa caacaaaacg gaaaccgtca gaaaaacgac ggccgtaatg
     7321 gtggaaaaca aggtcaaagc aaccgcgaca atcgtcgctt taatgaccaa gctaagaagc
     7381 agcaaggtca gcaaaaacgt agaaatgagc gccgtcagca agaggataaa cgttcaaatc
     7441 aagcggctcc acgtattgac tttaaagccc gtgcagcagc cctaaaagca gagcaaaatg
     7501 cagagtacgc tcgttcaagt gaggaacgct tcaagcagta tcaggctgct aaagaagcct
     7561 tggctcaagc taacaaacgc aaggaaccag aggaaatctt tgaagaagcg gctaagttag
     7621 ctgaacaagc acagcaagtt caagcagtgg ttgaagtcgt ccctgagaaa aaagaacctg
     7681 cagtggatac acgtcgtaaa aaacaagctc gaccagacaa aaatcgtgac gattatgatc
     7741 atgaagaaga tggtcctaga aaacaacaaa agaatcgaag tagtcaaaat caagtgagaa
     7801 atcaaaagaa tagtaactgg aataacaaca aaaagaacaa aaaaggcaat aacaagaaca
     7861 accgtaatca gactccaaaa cctgttacgg agcgtaaatt ccatgaattg ccaacagaat
     7921 ttgaatatac agatggtatg accgttgcgg aaatcgcaaa acgtatcaaa cgtgaaccag
     7981 ctgaaattgt taagaaactt ttcatgatgg gtgtcatggc cacacaaaac caatccttgg
     8041 atggggaaac aattgaactc ctcatggtgg attacggtat cgaagccaaa caaaaggttg
     8101 aagtggataa tgctgacatc gaacgtttct ttgtcgaaga tggttatctc aatgaagatg
     8161 aattggttga gcgtccacca gttgttacta tcatgggaca cgttgaccac ggtaaaacaa
     8221 cccttttgga tactcttcgt aactcacgtg ttgcgacagg tgaagcaggt ggtattactc
     8281 agcatatcgg tgcctaccaa atcgtggaaa atggtaagaa gattaccttc cttgatacac
     8341 caggacacgc ggcctttaca tcaatgcgtg cgcgtggtgc ttctgttacc gatattacga
     8401 tcttggtcgt agcggcagat gacggggtta tgcctcagac tattgaagcc atcaaccact
     8461 caaaagcagc taacgttcca atcatcgtag ctattaacaa gattgataaa ccaggtgcta
     8521 acccagaacg cgttatcggt gaattggcag agcatggtgt gatgtcaact gcttggggtg
     8581 gagattctga atttgttgaa atttcggcta aattcaacca aaatatcgaa gaattgttgg
     8641 aaacagtcct tcttgtggct gaaatccaag aactcaaagc agacccaaca gttcgtgcga
     8701 tcggtacggt tatcgaagcg cgcttggata aaggaaaagg tgcggtcgca acccttcttg
     8761 tacaacaagg taccttgaat gttcaagacc caatcgttgt cggaaatacc ttcggtcgtg
     8821 tccgtgctat gaccaacgac cttggtcgtc gtgttaaagt tgctggacca tcaacaccag
     8881 tctctatcac aggtttgaac gaagcaccga tggcgggtga ccactttgcc gtttacgagg
     8941 atgaaaaatc tgcgcgtgca gcaggtgaag agcgtgccaa acgtgccctc atgaaacaac
     9001 gtcaagctac ccaacgtgtt agccttgaaa acctctttga tacccttaaa gctggggaac
     9061 tcaaatctgt taatgttatc atcaaggctg atgtacaagg ttctgttgaa gccctttctg
     9121 cctcacttca aaagattgac gtggaaggtg tcaaagtgac tatcgtccac tcagcggtcg
     9181 gtgctatcaa cgaatcagac gtgacccttg ccgaagcttc aaatgccttt atcgttggtt
     9241 tcaacgtacg ccctacacca caagctcgtc aacaagcaga agctgacgat gtggaaatcc
     9301 gtcttcacag cattatctac aaggttatcg aagagatgga agaagctatg aaagggatgc
     9361 ttgatccaga atttgaagaa aaagttattg gtgaagcggt tatccgtgaa accttcaagg
     9421 tgtctaaagt gggaactatc ggtggattta tggttatcaa cggtaaggtt gcccgtgact
     9481 ctaaagtccg tgttatccgt gatggtgtcg ttatctatga tggtgaactc gcaagcttga
     9541 aacactataa agacgacgtg aaagaagtga caaacggtcg tgaaggtgga ttgatgatcg
     9601 acggctacaa tgatattaag atggatgatg tgattgaggc gtatgtcatg gaagaaatca
     9661 agagataaga ttttttgctc ctttcttagg tggtgaggga cgcaagcaaa ccgatggttt
     9721 cattgcttat ttttgagcct agggtctcaa aaatcccctg tgatgggact gataaatcag
     9781 ttccatcact ttcaccacgg cgaaagaagc agatgacttc aaattgaact tcgtttcaat
     9841 ttaaactgaa aatcaagaag tttaaaatag ctaggtctgc tggcctagct tttggttcaa
     9901 agtagagaaa ggaatatcat ggcaaatcat ttccgtacag atcgtgtggg catggaaatc
     9961 aagcgtgaag tcaatgagat tttgcaaaag aaagtccgtg atccacgtgt ccaaggtgtg
    10021 accatcatag atgttcagat gctgggtgac ttgtctgttg ccaaggttta ttacaccatt
    10081 ttgagtaacc ttgcttcgga taaccaaaaa gcccaaatcg ggcttgaaaa agcaactggt
    10141 accatcaaac gtgaacttgg tcgcaatttg aaattgtaca aaatcccaga tttgaccttc
    10201 gtcaaagacg agtccatcga gtatggaaac aagattgacg agatgctacg caatctggat
    10261 aagaactaaa gaagaggggt tgcccctctt ttttggtgga ggaaaatagg ttgaatttga
    10321 aatggaaaaa tattctttta taatagattg aaactagaat agtacgcctc tacttctaaa
    10381 atattgttag aaatcgattt gactgtcctg atcgatttgt cctgttcttg tttcatttta
    10441 atataaaaaa gggattctgt attttttaat gttatctaat tagaaaatgc tttttttgta
    10501 ggaaatataa tatgataagg tgcaaaaaag aaataaggag tttgtatatg gctgaacaag
    10561 acttagctat gcaagtattg caacaagtgg tgaaactacc tgttgttaag gttgatcgtt
    10621 cgaaattttt agtggataag ttttccaaag aattggatcc aaaagatatt cctaccttat
    10681 tggaacaagg tccaacgact cttctatctc aagaaatatt agatcgtgta gctaatgctt
    10741 gtattcggga caatgtatta ttagcgagtg ggacttctgt tttggcagga ttacctggag
    10801 ggcttgctat ggcaattacc attccagctg atgtggctca attttatgct ttctctctga
    10861 aattggctca agaattaggt tatatttatg gttatgagga tctttgggct tcacgagagg
    10921 agttgagtga agatgctcaa aataccctct tgctttatct aggcgtaatg ttaggggtga
    10981 atggaaccgc tgctttgcta cgtgttggta gtataacaat tgccaaacag gtaatgaaaa
    11041 tagtgcctaa taaagcttta acaaagacgc tttggtaccc tattttgaaa aaagtcttaa
    11101 aaatatttgg tgtgaatctt accaagggag ggttggccaa aggaatgggg aaatttattc
    11161 ctatcttggg tggtatcatt tcaggtggtt taacctttgc aactatgaaa ccaatggggg
    11221 aaagcttgca gaaagaatta tccaagctag tcaactatag tgaagttcaa tatcaagaag
    11281 atgttgaaac aatccgaaaa gaggctgaaa tcatcaaagg agagtaatat gaatcctatc
    11341 aaagcttttg ctaaaattta tggtaattac tttttgaccg tgcaaggtgt aaaagtgatg
    11401 aaaacgataa agaaagctga ccatgtcgtt gttggtctgg ggaaactttt tattgccgac
    11461 aagttaatgg atacggctcg gtggctcatt aagccagagg agagagaatg aaattttttt
    11521 ggtcttcttg ctattctttt tatcaaaccg attattggga ttgtgaaatt cttttggatg
    11581 atcatctctt ttgcagtcca attgctgttt tacaagatag tgtttaagat attggattgg
    11641 ctctttaaac ttatctagat ggtaatccaa gttgcagaga actagcagga actccactgc
    11701 tagtttttta ttctctttcc atatggtata atataagcag taaaatcatt ttatactctt
    11761 cgaaaatctc ttcaaaccac gtcagcttca ccttgcagta tatatgttac tgacttcgtc
    11821 agttctatcc acaacctcaa aacggtgttt tgagctgact tcgtcagttc tatctacaac
    11881 ctcaaaacac tgttttgagc aacctgcggc tagcttccta gtttgctctt tgattttcat
    11941 tgagtattag aacatacaat ggaggtcgtc atggacaata tcatcgatgt gtcaattcct
    12001 gttgcagaag tggtggacaa gcatccagaa gtcttggaaa ttctagtgga gttgggtttt
    12061 aaaccccttg ccaatccctt aatgcgcaat acagttggtc gtaaagtatc acttaaacag
    12121 ggttctaagc tagcaggaac tcctatggac aagattgtac gcacactgga agcgaatggc
    12181 tacgaagtga ttggattaga ctaatgacag atgaacggat tcatatccta cgggatattt
    12241 tgttagaatt gcacaatggc gcctctcctg agtcggttca agatcgcttt gatgcgacct
    12301 ttacgggcgt gtcagccatc gagatttccc ttatggagca cgagctgatg aactcggatt
    12361 cgggcgtcac ttttgaagat gttatggaac tctgtgatgt ccatgccaat ctttttaaaa
    12421 atgctatcaa aggtgtcgaa gtttcagata ctgagcatcc aggtcaccca gttcgtgtct
    12481 tcaaagaaga aaatctggct ctccgtgcgg ccttgattcg cattcgtaga ttgttagata
    12541 cctatgagtc tatggaagac gaggaaatgc tggcggagat gcgtaagggt ttggtgcgtc
    12601 agatgggact tgtgggtcaa tttgacatcc attaccaacg taaggaagaa ctcttctttc
    12661 ctatcatgga gcgctatgga cacgattcac ctcccaaagt tatgtgggga gtggatgatc
    12721 agattaggga actctttcaa acagctctaa cgacagccaa gtcactacca gaagtgtcaa
    12781 ttagcagtgt aaaggaagct tttgaagctt ttgcgacaga gtttgaaagt atgattttca
    12841 aggaagagtc catcctcctc atgattctcc ttgagtcttt tactcaggat gactggcttc
    12901 agattgcgga ggagagcgat gcctatggct atgccatcat ccgtccgtca gagaaatggg
    12961 tgccagaacg acagagcttt attgaggaaa agattgcaga ggagcctgta cagctagata
    13021 cggcagaagg tcaagttcaa caagtcatag atacgccaga aggccatttt accattacct
    13081 ttacccctaa ggaaaaggaa gctgtgctgg accgccatag tcaacaggct tttggtaatg
    13141 gctatctttc agtcgagcag gccaatctca tcctcaatca tctccctatg gagattacct
    13201 ttgtcaataa agaagatatt ttccagtatt acaatgacaa tacgccagct gatgagatga
    13261 ttttcaaacg gacgccgtcc caagtcgggc gcaatgtcga actctgccat ccgcctaagt
    13321 acttggacaa ggtcaaaact atcatgaagg ggcttcgtga gggaagcaaa gacaagtatg
    13381 aaatgtggtt caagtctgag tcgcgaggta agtttgtcca catcacctat gctgcagtac
    13441 acgatgaaga cggagaattc caaggagtgt tggagtatgt tcaggatatc cagccctacc
    13501 gtgagattga tacggactat tttcgtggat tagaataagg agaaaaaatg agttacgaac
    13561 aagaatttat gaaggaattt gaagcttggg tcaataccca aatcatgatt aacgacatgg
    13621 cgcacaagga aagccaaaaa gtttacgaag aagaccagga cgagcgtgcc aaagatgcca
    13681 tgattcgcta cgagagtcgc ttggatgctt atcagttctt gcttggtaag tttgaaaact
    13741 tcaaagtagg caagggattc catgatttgc cagaaggctt gtttggtgag cgaaattatt
    13801 aaacgagaaa gattcttgat ttttcactaa aatcttgata gaatgtttat gttaaatcct
    13861 tgtcagagca gggatttttt attgaaagga ttttatcatg tcaaagaaac tcaatcgtaa
    13921 aaaacaatta cgaaatggcc tccgtcgcgc aggtgccttt tcaagtacgg tgactaaggt
    13981 tgtagatgag acaaaaaaag tcgtgaagcg tgcagaacag tcagcaagcg cagctggtaa
    14041 ggctgtttct aaaaaagttg aacaagcagt agaagctacc aaagagcaag ctcaaaaagt
    14101 agctaattct gtagaagatt ttgcagcaaa tttgggtgga cttccacttg atcgtgccaa
    14161 gactttctat gatgaaggaa tcaagtctgc ttcagatttc aaaaactgga ctgaaaaaga
    14221 actccttgcc ttgaaaggaa tcggcccagc taccatcaag aaattgaaag aaaatggcat
    14281 caagttcaag taatttttct tgagccttgc atttccgaaa aaatcttgct acaatagagc
    14341 cattagaggt gttttgaatc ccacatttta cagaaagtgg cggcgctgag aagtccacaa
    14401 atgtgtcaaa actggttgct aatggatgaa aaattgaaat aaaagtgtct ttttgcttta
    14461 aagacgagag ttgcgggcaa ctgcccgaaa ttgggtggta ccgcggataa acacattcgt
    14521 ccctgtcatg tagatggcag ggcttttctt ttacgtctta gtcaaagggg gttgttatga
    14581 agcaatcttt taacacaagt aaactatatt atggttttcc tgtttttatt ttaggatatc
    14641 aagattagaa ttttggctat aacatcacga cctgtagttc ctcttatagt ctaggagatt
    14701 gggttgtgat tggagtcgtt gcgagagaga atgccgcaga gcagatcaaa cagtatcaaa
    14761 aatttactgt gaatatttct gatgaaactt ctatgcttgc gatggagcag gctggtttta
    14821 tcagtcatca ggagaaattg gaacgtttgg gagtgcatta tgaaatttct gaacgaactc
    14881 agactcctat tttagacgcc tgtccacttg ttttagattg tcgggtagat aggattgttg
    14941 aggaagacgg tatttgccac atctttgcca agattcttga gcgacttgtt gccccagaac
    15001 tcctggatga aaagggacat tttaaaaatc aactgtttgc cccaacctat ttcatgggag
    15061 atggatatca gcgcgtttat cgctatctgg acaagcgtgt agatatgaag ggcagtttca
    15121 tcaaaaaagc gaggaagaag gatggcaaga actgagctgc cagataaaat cgaaacagaa
    15181 cgtctcgttt tacgagtccg cacagtggtg gatgctgagg atatccatac ctacgctagt
    15241 ttgccagagg tcgcctatcc agcaggtttt cctccagtca agatcttgga agatgagatt
    15301 tattatctgg agcacattct tccggagcgt actcaaaagg aaaatctccc agctggctat
    15361 gggattgtcg tcaaaggaac cgataaagtc attggttctg ttgacttcaa ccatcttcat
    15421 gcggatgatg tgctagagct tggctatacc ttgcacccag actattgggg tcgaggttat
    15481 gttccagaag cagcgtgttc cttgattgat ctagctttta aagaacttgg tcttcacaag
    15541 attgaactaa cttgctttgg atataacctt caaagtcaac gagtctcgga aaagcttggc
    15601 tttaccctcg aagctcgcat aagagaccgc aaagatgctc aaggcaactg ctgtgatgat
    15661 ttgagatatg gcttgctgag gagtgagtgg gaggtgattt gatgcatctt ttcatcattg
    15721 gtgctccagc atcaggaaaa atgaccattg gtcaagaatt atctcgactg acggatgcta
    15781 ccctatttta taaccatcaa gccattgatt ttgcactaga gatctatcag gattataccg
    15841 aggagatgtg ggaatttgtt cgtggaatta ccttttcttt ccttggagca agtgcaagaa
    15901 atcagcgatc agtaatttta acagacgtaa ttgatttttc aaatcagtac cagctgatgt
    15961 atttaaagca aattcaggat ttattggata actttcatca agagattctg tttgttgaat
    16021 tggaaacaag tcttgaagag tgcatacgtc gaaatcgaac ggagaatcga ttaaagcaca
    16081 aacccttaaa acgacatatt gaggtatctg aaagagaaat tttagagacc gctgaaacac
    16141 ttcaattaaa ttcccaacat caaccgaatg agttgcacca ctactttaaa ataaataata
    16201 cgaatttgtc tgcagaagaa gctgctaagc aaattcaaaa taaaataaac aaaatagaga
    16261 aaggacacac acatgtctaa agaactttca cctaaataca atccagccga ggttgaggct
    16321 ggtcgttacc aaaaatggct tgatgcggat gttttcaagc cttcaggcga tcaaaaggct
    16381 aagccttatt caatcgtgat tccaccacca aacgtaactg ggaaacttca ccttggtcac
    16441 gcttgggata cgactttgca ggatatcatc atccgtcaaa aacgcatgca aggctttgat
    16501 accctttggc ttccaggtat ggaccacgct ggtattgcga ctcaggctaa ggttgaggag
    16561 cgcttacgtg gtgagggtat tacgcgttat gacctaggtc gtgagtcttt cttgacgaag
    16621 gtctgggaat ggaaagacga atatgccact accatcaagg aacaatgggg caagatgggg
    16681 ctttctgtag actattctcg tgagcgtttc actcttgatg aaggtttgtc aaaagctgtt
    16741 cgtaaggtct ttgtgaacct ttacaagaaa ggctggatct atcgtggtga gtttatcatc
    16801 aactgggacc cagcagctcg cacagccctt tctgatattg aggtgattca caaggatgta
    16861 gaaggtgcct tctaccacat gaattacatg ctggaagatg gttcacgcgc ccttgaagtt
    16921 gctacaactc gtcctgagac tatgtttggg gacgttgcgg ttgcggttaa tccagaagac
    16981 ccgcgctaca aggacttgat tggtaaaaac gtcatccttc caatcgctaa taaactcatc
    17041 ccaatcgttg gagatgagca cgcagatcct gagcttggta ctggtgtcgt gaaaatcaca
    17101 cctgcccacg atccaaatga cttcttggtt ggccaacgtc ataacttgcc acaagtcaac
    17161 gtcatgaacg acgacggaac tatgaatgag cttgcctttg aattttcagg catggatcgt
    17221 tttgaagctc gtaaggcagt cgttgctaag ttggaagaaa tcggtgccct tgtcaaaatc
    17281 gaaaaacgtg tccacagtgt tggtcactca gaacgtacag gtgtcgtagt tgagccacgc
    17341 ttgtctactc aatggttcgt caagatggac caattggcta agaacgccat tgctaaccaa
    17401 gacacagagg acaaggtcga attctaccca cctcgtttca acgatacctt ccttcaatgg
    17461 atggaaaatg tccacgactg ggttatctct cgtcagcttt ggtggggtca ccaaatccct
    17521 gcctggtaca atgctgatgg tgaaatgtat gtcggcgaag aagctccaga aggtgacgga
    17581 tggactcagg acgaagacgt cttggatact tggttcagtt ctgccctctg gccattttca
    17641 accatgggct ggcctgaagt cgactcagaa gactttaaac gttatttccc aacttcaacc
    17701 ttggtaacag gttacgacat catcttcttc tgggtgtctc gtatgatctt ccagtccttg
    17761 gaatttactg gtcgtcagcc attccaaaac gtgcttatcc acggtctcat ccgtgacgag
    17821 caaggacgca agatgtctaa atctctcggt aacgggattg acccaatgga tgtcatcgag
    17881 aaatacggtg ctgatgccct tcgttggttc ctttcaaacg gttccgcacc aggtcaagac
    17941 gttcgtttct cttacgagaa aatggatgct tcatggaact ttattaacaa aatttggaac
    18001 atttctcgct atatcctcat gaacaatgaa ggtttgacgc tggatgtggc gcatgacaat
    18061 gtcacaaaag ttgcaacagg tgaggctggt aatgtgacgg accgctggat tctccacaat
    18121 ctcaacgaaa ccattgcaaa agttactgaa aactttgata agttcgagtt tggtgtggct
    18181 ggtcatatcc tttacaactt catctgggaa gaatttgcca actggtatgt tgagttgacc
    18241 aaggaagttc tatacagcga caatgaagac gataaggtca ttactcgatc tgttctcctc
    18301 tatacgctgg acaagatcct tcgtctcctt cacccaatca tgccattcgt gacagaggaa
    18361 atctttggac aaatctcaga aggttctatc gtgacagctg catacccaac tgttaatcta
    18421 gcctttgaag accttgcggc tcacactggt gtggaaagtc tcaaagactt gattcgtgct
    18481 gttcggaatg cgcgtgcgga agtaaatgta gcaccaagca agcctatcac catccttgtt
    18541 aagacaagcg atagcgactt ggaagccttc tttaacagca atgtcaacta tatcaaacgc
    18601 tttacaaatc cagaacactt ggaaatcgca tcaaccatcc ctgcacctga actggctatg
    18661 tcaagtgtca tcacaggagc agaaatctac ctgccactgg ccgatctcct caatgttgaa
    18721 gaagaactgg cccgtctcga caaggaactt gctaaatggc aaaaagaact ggacatggtt
    18781 ggtaagaaac tctctaacga acgcttcgta gccaacgcca aaccagaagt cgtccaaaaa
    18841 gaatgcgaca aacaagctga ctaccaagct aaatatgacg cgaccgtcgc acgtattgat
    18901 gagatgaaga agttggtgaa atgatgttaa aaacctaacc ctatcgggtt gggttttaca
    18961 tttgataatg ttataataaa aaggagaaac tttaggagaa tactatgggg aaaattgttg
    19021 ctattgattt atttaacggt gcaggtggca ctacaagtgg ccttaaaaaa tcaggcatag
    19081 atgttcaagt tgctgttgaa attgattccg tagctgttaa aacttataag ttaaataatc
    19141 ctgaggtgtc tgtaatagat atggagtaaa taaaacttca attttacaag ctttatatgg
    19201 ttctccagcc aataaaagtg tgtctgaata ttggtttagt acaaatgttg atcaaataga
    19261 tgaagtggat gggaaacaat gtttaatcta ttcatattat aacattaaag cttctagaaa
    19321 tgtagaagtt cttaaaggcc gttctggaac aaaaaaagga ttagattatt gggaaccata
    19381 tgctcctcaa aaacaatatg agatggaaag attacccaaa aataaatata ttggaagttc
    19441 ttcgacagac agatgggatg gcattgaaaa aaatgttgtc ttttgtgatt gtaaagaata
    19501 tgtttctgct tttgatttat ttttctatca ctataatttt aaaaaaattt ctactcaacg
    19561 tagtaaacaa gattttataa gattacgatc taagccagtt gctgatattt taaagaataa
    19621 tacaagtagc tatacgcgtt ataaaaagga aatggttata gataatgtta aagttgatga
    19681 taaagtttgt gaaattatta gtgaaataat ggatgaatct tatacagaca ttcaaatttt
    19741 aacacataag ttgtattcaa aaggtgatga tataaaagct tccaaaacta tttggatgaa
    19801 aaaatctgga aaagaatatt ccgaggcttt tgcaggaaca ggtgaggcta gaattatttt
    19861 gttagtaaat gatatagtaa atgcgcaatc aaattcatta atattaatag atgaacctga
    19921 aatctcactt catccgagtg caatctataa atttaaagag tttttacttc aagagtgttt
    19981 aaataaaaaa catcaaatta ttatcactac acattctaca caacttataa aagattttcc
    20041 tagagaagcc gtgaaacttt tagtgaaaaa cggagaaaag gtagatgtta ttgaaaatat
    20101 tgattatcag gatgcatttt ttgaattagg tgatgtgtat cattctagga agatgattta
    20161 tgttgaagat agactagcta aatatattct agagtttgtt atcactcatt caggtagtga
    20221 gaatcttaaa cagaatttag tagtgagata tattcctggt ggagcaaatc aaataatttg
    20281 taataatatt ttaaactcat cgtatttaga ttccgataac cattattttt ggcttgatgg
    20341 agatcaaaac actaatgtta gtgaatcaaa taatttaatg aactatcttg aaaatggtgt
    20401 tgttatatca gataaaattc ctgaatcaga taataaaaat cttgatgata ttataaaatt
    20461 gataacggga tgtccaatta aatttaatgt ttcaggtaat aaagggcaaa aaaataatat
    20521 tgaattaatt gcgaaacaaa gaagctttat agattattgg gctaaatacg tttcttatct
    20581 tcctttccca accccagagt tttttttagc taatttgtgt aacagcgtag atagggaagg
    20641 ttatgatttt tctaaagatg gcaacggaaa agaatatttt agaaaaaaaa ctcaagtagc
    20701 gttaggaata gagaatataa cttctgaaga tattttccag gagcaaagaa gagctgtttc
    20761 aaaaatacag ccagaatcat caatgtttca gtgtattaaa gaaaaattag aggcattgtt
    20821 ctaattcctt agattaggta ctacataaca aattttttaa attcaaaccc gcaccaaaaa
    20881 caacattgca actttcttct caggtaatgt gttgggattt gaacagacca acgagttcat
    20941 agtggtgtat gccaatgact ttgataagtc tacgcgtcag acttattagt tcatttatcc
    21001 agatatatct cgataatcat attatttagt caaagaacat cccatatgag ggcatgaaat
    21061 gctaagttta gcttgctcac tattaagatg aagtatatat atttcataga acctattgtg
    21121 aaggattttt ataattttcg ccaattccat acctatttca caatttaccg atgacacaga
    21181 aaaacaattg aaaggatatt tctatgcaac caacttacaa cattgacaat ccaaacttgt
    21241 cttatgaagc gaagcgtgat ttatggcgga taggttttgg tctgcagaaa gttgacaatc
    21301 tagtgccatc agcgtatatg gaatctttgg ctgagaaaca gtcccggggt gaactgactt
    21361 atgagcaggt ttatgaggat gcaacggctt atcatcatac cattgatgcg agtacagagg
    21421 aggcagactt ggtttctcta cgtattgtag aactattgtc tcgaagaggc tttagcttca
    21481 gtcctgcgat cttacttgct attcataagg agttgtttca agatatattt gaaccctcga
    21541 ttccggtagg tcaatttcgt cagactaata tcacaaagaa tgaacctgtt ttgaatggtg
    21601 aaagtgttgt gtactctgat tactccatga ttcaaatgac cttggattat gattttaatc
    21661 aggaaaaaca agttgcatat gcgacactaa cccaggcgga tatggttaaa aaaatccagc
    21721 attttatttc aggaatctgg cagattcatc catttcgcga aggaaacact cggacggtaa
    21781 cggtattttt gattcagtat cttcgtgagt ttggttttga tattgataat acaccatttc
    21841 agcaacattc caagtatttt cgtgatgcct tagtgttaga taatgcaaag attttacagc
    21901 gacgtcctga gtttttaaca gctttttttg aaaatctctt gctcggtggt caaaatgatt
    21961 tgtcttcaga aaaaatgtat ctagatttag acctcgatct ttcataatcc taatactgag
    22021 taaacattga attttaggaa aaaatgaagt aaatattctc acaagaaaac gtatatcatc
    22081 aaagtttggc tctttgtcaa ttgtagtggg ttgaagaaaa gctaagttcg agaaaggaca
    22141 aatttcgtcc tttctttttt gatgttcaga gcgataaaaa tccgtttttt tgaagttttc
    22201 aaagtttcga aaaccaaagg cattgcgctt gataagtttg atgagattat tggtcgcttc
    22261 cagtttggca ttagaatagt gt
//
LOCUS       DAVFER010000035        21781 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1105170250
            SAMEA2167659-rid19724873.denovo.035, whole genome shotgun sequence.
ACCESSION   DAVFER010000035 DAVFER010000000
VERSION     DAVFER010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2167659
            Sequence Read Archive: ERR388902
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21781)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21781)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928716.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928716.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 04:07:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,118
            CDSs (total)                      :: 2,073
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 120
            CDSs (without protein)            :: 120
            Pseudo Genes (ambiguous residues) :: 0 of 120
            Pseudo Genes (frameshifted)       :: 67 of 120
            Pseudo Genes (incomplete)         :: 47 of 120
            Pseudo Genes (internal stop)      :: 34 of 120
            Pseudo Genes (multiple problems)  :: 23 of 120
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21781
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2167659-rid19724873.denovo.035"
                     /strain="1105170250"
                     /db_xref="taxon:1313"
     gene            527..1990
                     /locus_tag="VU534_001448"
     CDS             527..1990
                     /locus_tag="VU534_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000087917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HEU1514023.1"
                     /translation="MSRKQEQMETLLLLLRDSKDYISAKVLGEKLNCSDKTVYRLVKG
                     INKDCPVEAFILSEKGRGFKLNPRSSLVDVDGNFTEAFDPEVRREKLLERLLLTAPKP
                     HSIYDLGEEFYVSESVVLKDRQILQESLAIYGLDLKMRQRKLFIDGDEAQIRSAILNL
                     LPMFNQLDLEQITQNKVQPLDGELAHFCLGLLITLERELGVNIPYPYNINIFSHLYIF
                     ISRNRRSTSIHVVAPSKPTIVDEKIYSVCQKIIQEIEQYFRMKVDAVEIDYLYQYVVS
                     SRLQKPFSSGKLPFSQRVLDVTHYYFSRMCMDNREIETTDPDFVDLASHISPLLRRLD
                     NRVQIKNSLLSQILLTYPNLVKELTTISKEVSLVFGFASLSLDEIGFLVLYFARFQEK
                     RARPLKTVVMCTSGVGTSELLRARLEKQFSELDIIDVVAYHQLDELINLYPDLDFIVT
                     TVALQEPASVPFVLVSVFLTEGDKQRLQAKIQEINYE"
     gene            1983..2411
                     /locus_tag="VU534_001449"
     CDS             1983..2411
                     /locus_tag="VU534_001449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEU1514024.1"
                     /translation="MNNLSLVLMDISVQNRQEAYKELANQISLLVSEDTEKIEELLYY
                     RERQGSIEVAKGVLLPHCEGNFQHHVLVITRLKSPIREWSKDIQCVDLIIGLAIAVSQ
                     DKSCIKTLMRRLADESFINQLKQLTKEELREIIYGNQRYS"
     gene            2389..2838
                     /locus_tag="VU534_001450"
     CDS             2389..2838
                     /locus_tag="VU534_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEU1514025.1"
                     /translation="MEIKDILNVSLIQTDLQMQSKEEVFEALAQLLVETGYVSDRDQF
                     IEGLYQREAEGQTGIGNYIAIPHSKSSAVEKAGVVIAINHNEIPWETIDGKGVKVIVL
                     FAVGDDTEAAREHLKTLSLFARKLGNDEVVAKLVRAQTSDDVIAAFC"
     gene            2866..3177
                     /locus_tag="VU534_001451"
     CDS             2866..3177
                     /locus_tag="VU534_001451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIB"
                     /protein_id="HEU1514026.1"
                     /translation="MKIVGVAACTVGIAHTYIAQEKLENAAKVAGHVIHVETQGTIGV
                     ENELSQEQIDAADVVILAVDVKISGMERFEGKKIIKVPTEVAVKSPNKLIAKAVEIVT
                     K"
     gene            3203..4288
                     /locus_tag="VU534_001452"
     CDS             3203..4288
                     /locus_tag="VU534_001452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000912151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HEU1514027.1"
                     /translation="MLKHLNLKGHLLTAISYMIPIVCGAGFLVAIGLAMGGGVPDALV
                     AGKFTIWDALATMGGKALGLLPVVIATGLSYSIAGKPGIAPGFVVGLIANSVGSGFIG
                     GILGGYIAGFLVQAIIKKVKVPNWIKGLMPTLIIPFVASLVSSLIMIYIIGAPIAAFT
                     NWLTSLLQSLGSASNGLMGAVIGILSAVDFGGPLNKTVYAFVLTLQAEGVKEPLTALQ
                     LVNTATPVGFGLAYFIAKLLKKNIYTQEEIETLKSAVPMGIVNIVEGVIPIVMNNLVP
                     GLIATGIGGAVGGAVSLTMGADSAVPFGGVLMLPTMTRPVAGICALLANIVVTGLVYA
                     ILKKPIKHAEPVMTVEEEIDLSDIEIL"
     gene            4299..4994
                     /locus_tag="VU534_001453"
     CDS             4299..4994
                     /locus_tag="VU534_001453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000086495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HEU1514028.1"
                     /translation="MSRIEFSPSLMTMDLDKFKEQITFLNDKVASYHIDIMDGHFVPN
                     ITLSPWFIQEVQKISDTPLSVHLMVTDPTFWVDQVLDLQCEYICIHAEVLNGLAFRLI
                     DKIHDAGLKAGVVLNPETPVSTIFPYIDLLDKATIMTVDPGFAGQRFLESTLYKIQEL
                     RQLRVQNGYHYIIEMDGSSSRKTFKQIDVAGPDIYVIGRSGLFGLDDDIAKAWDICSR
                     DYEEMTGKTMPIK"
     gene            5031..6998
                     /gene="tkt"
                     /locus_tag="VU534_001454"
     CDS             5031..6998
                     /gene="tkt"
                     /locus_tag="VU534_001454"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000067884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HEU1514029.1"
                     /translation="MSLQSVNAIRFLGVDAINKSNSGHPGIVMGAAPMAYSLFTKHLR
                     ITPEQPNWINRDRFILSAGHGSMLLYALLHLTGYKDVSMDEIKNFRQWGSKTPGHPEV
                     THTSGVDATSGPLGQGISTAVGFAQAERFLAAKYNKDGFPIFDHYTYVIAGDGDFMEG
                     VSAEAASYAGHQALDKLIVLYDSNDICLDGETKDTFSENVRVRYDAYGWHTVLVEDGT
                     DLAAISTAIETAKFSGKPSLIEVKTVIGYGSPNKSGTNAVHGAPLGAEETGATRKFLG
                     WDYDPFEVPEEVYSDFKTNVADRGQEAYDAWASLVSDYKVAYPEVASEIDAIVAGKSP
                     VTITEKDFPVYENGFSQATRNSSQDAINTAAVLPTFLGGSADLAHSNMTYIKADGLQD
                     KYNPLNRNIQFGVREFAMGTILNGMALHGGLRVYGGTFFVFSDYVKAAIRLSAIQELP
                     VTYVFTHDSIAVGEDGPTHEPVEHLAGLRSMPNLTVIRPADARETQAAWHHALTSTTT
                     PTVIVLTRQNLVVEEGTDFGKVAKGAYVVYDTPGFDTIIIATGSEVNLAIKAAKELVL
                     QGGKVRVVSMPSTELFDAQDATYKEDILPSKTRRRVAIEMAATQSWYKYVGLDGAVIG
                     IDIFGASAPAQTVIDNYGFTVENIVAQVKSL"
     gene            7373..8644
                     /locus_tag="VU534_001455"
                     /pseudo
     CDS             7373..8644
                     /locus_tag="VU534_001455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(8718..9248)
                     /locus_tag="VU534_001456"
     CDS             complement(8718..9248)
                     /locus_tag="VU534_001456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000883388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein kinase family protein"
                     /protein_id="HEU1514030.1"
                     /translation="MLDEKRKNYVEDKRQNFPSLPSWKMDLFSEEEKRIYFQTTCEVS
                     SKDSAINKYKMEKIIKRSNKGNVYRAIRKSDGQKVIIKQSRPFVNYDAEGEWTALDDI
                     KNEAHMLKKLADKSYTTNLTDEFYIVDDYFLVQEQVDGLNFEEFIRETEHSLNIREKT
                     LDNIVNIVSYIHKLGI"
     gene            complement(9242..9710)
                     /locus_tag="VU534_001457"
                     /pseudo
     CDS             complement(9242..9710)
                     /locus_tag="VU534_001457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847907.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            10259..10936
                     /locus_tag="VU534_001458"
     CDS             10259..10936
                     /locus_tag="VU534_001458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000624068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine-N(1))-methyltransferase"
                     /protein_id="HEU1514031.1"
                     /translation="MISKRLELVASFVSQGAILLDVGSDHAYLPIELVERGQIKSAIA
                     GEVVEGPYQSAVKNVEAHGLKEKIQVRLANGLAAFEETDQVSVITIAGMGGRLIARIL
                     EEGLGKLANVERLILQPNNREDDLRIWLQDHGFQIVAESILEEAGKFYEILVVEAGQM
                     KLSASDVRFGPFLSKEVSPVFVQKWQKEAEKLEFALGQIPEKNLEERQVLVDKIQAIK
                     EVLHVSK"
     gene            10923..11720
                     /locus_tag="VU534_001459"
     CDS             10923..11720
                     /locus_tag="VU534_001459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000881127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HEU1514032.1"
                     /translation="MLASEVIQAYEAFCPQEFSMEGDSRGLQIGTLDKGIQRVMVALD
                     IREETVAEAIEKGVDLIIVKHAPIFRPIKDLLASRPQNQIYIDLIKHDIAVYVSHTNI
                     DIVENGLNDWFCQMLGIEETTYLQETGPERGIGRIGNIQPQTFWELAQQVKQVFDLDS
                     LRMVHYQEDDLQKPISRVAICGGSGQSFYKDALAKGADVYITGDIYYHTAQDMLSDGL
                     LALDPGHYIEVIFVEKIAALLSQWKEDKGWSIDILPSQASTNPFHHI"
     gene            11737..12840
                     /locus_tag="VU534_001460"
     CDS             11737..12840
                     /locus_tag="VU534_001460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HEU1514033.1"
                     /translation="MKKVAIIGAGIVGATAAYYLSRESDLEVTVFDHEQGQATKAAAG
                     IISPWFSKRRNKAWYKMARLGADFYVDLLADLEKSGQEIDFYQRSGVFLLKKDESNLE
                     ELYQLALQRREESPLIGQLAILNQASANELFPGLQGFDRLLYASGGARVDGQLLVTRL
                     LEVSHVKLVKEKVTLTPLASGYQIGEEEFEQVILATGAWLGDMLEPLGYEVDVRPQKG
                     QLRDYQLAQDMEDYPVVMPEGEWDLIPFAGGKLSLGATHENDMGFDLTVDETLLQQME
                     EATLTHYLILAEATSKSERVGIRAYTSDFSPFFGQVPDLTGVYAASGLGSSGLTTGPI
                     IGYHLAQLIQDKELTLDPLNYPIENYVKRVKSE"
     gene            13141..14160
                     /gene="galE"
                     /locus_tag="VU534_001461"
     CDS             13141..14160
                     /gene="galE"
                     /locus_tag="VU534_001461"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HEU1514034.1"
                     /translation="MQEKILVTGGAGFIGTHTVIELIQAGHQVVVVDNLVNSNRKSLE
                     VVEGITGVEIPFYEADIRDTDTLRDIFKQEEPTGVIHFAGLKAVGESTRIPLAYYDNN
                     IAGTVSLLKAMEENNCKNIIFSSSATVYGDPHTVPILEDFPLSVTNPYGRTKLMLEEI
                     LTDIYKADSEWNVVLLRYFNPIGAHESGDLGENPNGIPNNLLPYVTQVAVGKLEQVQV
                     FGDDYDTEDGTGVRDYIHVVDLAKGHVAALKKIQKGSGLNVYNLGTGKGYSVLEIIQN
                     MEKAVGRPIPYRIVERRPGDIAACYSDPAKAKAELGWEAELDITQMCEDAWRWQSKHP
                     NGFED"
     gene            14162..15127
                     /locus_tag="VU534_001462"
     CDS             14162..15127
                     /locus_tag="VU534_001462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEU1514035.1"
                     /translation="MMISIIVPCLNEEEVLPLFYQALEALLPDLETEIEYVFVDDGSS
                     DGTLELLKAYREQNPAVHYISFSRNFGKEAALYAGLQYATGDLVVVMDADLQDPPSML
                     FEMKNVLDKNVDLDCVGTRRTSREGEPFFRSFCAVLFYRLMQKISPVALPSGVRDFRM
                     MRRSVVDAILSLTESNRFSKGLFAWVGFKTYYLDYPNVERQAGKTSWSFRQLFFYSIE
                     GIINFSDFPLIIAFVAGLLSCFLSLLMTFFVVVRTLILGNPTSGWTSLMAVILFLGGI
                     QLLTIGILGKYISKIYLETKKRPLYLIKEKSDLPDFTEKNKVKRL"
     gene            complement(15178..15384)
                     /locus_tag="VU534_001463"
     CDS             complement(15178..15384)
                     /locus_tag="VU534_001463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HEU1514036.1"
                     /translation="MKITLIPERCIACGLCQTYSDLFDYHDNGIVRFYDDPDQLEKEI
                     SPSQDILEAVKNCPTRALIGNQEA"
     gene            15436..15912
                     /locus_tag="VU534_001464"
     CDS             15436..15912
                     /locus_tag="VU534_001464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM domain-containing protein"
                     /protein_id="HEU1514037.1"
                     /translation="MAKEPWQEDIYDQEESRAERRHRNHGGADRMANRILTILASIFF
                     VIVVVMVIVLIYLSSGGSNRTAALKGFHDSDASVVQISSSSSSQPEQSSEPESTSSSS
                     EEAANPEGTIKVLAGEGEAAIAARAGISIAQLEALNPGHMATGSWFANPGDVIKIK"
     gene            15921..16592
                     /locus_tag="VU534_001465"
     CDS             15921..16592
                     /locus_tag="VU534_001465"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000849376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HEU1514038.1"
                     /translation="MKTIQIAIDGPASSGKSTVAKIIAKDFGFTYLDTGAMYRAATYM
                     ALKNQLGVEEVEALLALLDQHPISFGRSETGDQLVFVGDVDITHPIRENEVTNHVSAI
                     AAIPQVREKLVSLQQEIAQQGGIVMDGRDIGTVVLPQAELKIFLVASVDERAERRYKE
                     NIAKGIETDLETLKKEIAARDYKDSHRETSPLKQAEDAVYLDTTGLNIQEVVEKIKAE
                     AEKRM"
     gene            16723..17061
                     /locus_tag="VU534_001466"
     CDS             16723..17061
                     /locus_tag="VU534_001466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002920966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkylphosphonate utilization protein"
                     /protein_id="HEU1514039.1"
                     /translation="MNNLPNCPKCNSEYVYEDGALLVCPECAHEWNPAEVAEVEEGLV
                     AIDANGNKLADGDTVTLIKDLKVKGAPKDLKQGTRVKNIRIVEGDHNIDCKIDGFGAM
                     KLKSEFVRKI"
     gene            17064..17693
                     /locus_tag="VU534_001467"
     CDS             17064..17693
                     /locus_tag="VU534_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000033944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Pr6Pr family membrane protein"
                     /protein_id="HEU1514040.1"
                     /translation="MSKHYKLVFYSRIFLFLAAFTGVYLEITKHGGFGMLLYYTVLSN
                     LLVTIFTLYLLKVMSRVGENWQRPSLLRLKGGVTMSIMITCVIYHFLLAPIATNFYTL
                     ENFLCHYIVPIWFLADTLFFDKQGQYKIWDPAVWTILPFLYMMFALFNGLVLKLNIPN
                     AKDNPFPYFFLNVNKGWNVVFKWCLIIFVAYMVAGFIFYFIKQIKRKSS"
     gene            17933..19084
                     /locus_tag="VU534_001468"
     CDS             17933..19084
                     /locus_tag="VU534_001468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEU1514041.1"
                     /translation="MKQFLERASILALSLVLITSFSISSALPAMFDYYQGYSKEQIEL
                     LVSLPSFGIMMMLLLNGFLEKIFPERLQISLGLLILSLSGTAPFWYQAYPFVFGTRLL
                     FGLGLGMINAKAISIISERYQGKRRIQMLGLRASAEVVGASLITLAVGQLLAFGWTAI
                     FLAYSAGFLVLPLYLLFVPYGKSKKEVKKRAKEASRLTREMKGLIFTLAIEAAVVVCT
                     NTAITIRIPSLMVERGLGDAQLSSFVLSIMQLIGIVAGVSFSFLISIFKEKLLLWSGI
                     TFGLGQIVIALSSSLWVVVAGSVLAGFAYSVVLTTVFQLVSERIPAKLLNQATSFAVL
                     GCSFGAFTTPFVLGAIGLLTHNGMLVFSILGGWLIVISIFVMYLLQKRA"
     gene            19402..20151
                     /gene="truA"
                     /locus_tag="VU534_001469"
     CDS             19402..20151
                     /gene="truA"
                     /locus_tag="VU534_001469"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HEU1514042.1"
                     /translation="MTRYKATISYDGYAFAGFQRQPHARSVQEEIEKTLTRLNKGQAI
                     TVHGAGRTDSGVHALGQVIHFDLPYQMDEEKLRFALDTQSPEDIDVISIELVADDFHC
                     RYAKHSKTYEFTVDRGRPKNPMRRHYATHFPYPLDVERMQIAIKKLEGTHDFTGFTAS
                     GTSVEDKVRTITEASLIVDETGQFLTFTFSGNGFLYKQIRNMVGTLLKIGNNRMPVEQ
                     IDLILEKKDRQLAGPTAAPNGLYLKEIRYEE"
     gene            20141..20914
                     /locus_tag="VU534_001470"
     CDS             20141..20914
                     /locus_tag="VU534_001470"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HEU1514043.1"
                     /translation="MKNNRILALSGNDIFSGGGLSADLATYTLNGLHGFVAVTCLTAL
                     TEKGFEVFPTDDTIFQHELDSLRDVEFGGIKIGLLPTVSVAEKALDFIKQRPGVPVVL
                     DPVLVCKETHDVAVSELCQELIRFFPYVSVITPNLPEAELLSGQEIKTLEDMKTAAQK
                     LHDLGAPAVIIKGGNRLSQDKAVDVFYDGQTFTILENPVIQGQNAGAGCTFASSIASH
                     LVKGDKLLPAVESSKAFVYRAIAQADQYGVRQYEANKNN"
     gene            20892..21353
                     /locus_tag="VU534_001471"
     CDS             20892..21353
                     /locus_tag="VU534_001471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEU1514044.1"
                     /translation="MKQTKTTKIALVSLLTALSVVLGYFLKIPTPTGILTLLDAGVFF
                     AAFYFGSREGAVVGGLASFLIDLLSGYPQWMFFSLVNHGLQGFFAGFKGKSQWLGLIL
                     ATIAMVGGYALGSALMNGWAAALPEILPNFMQNMVGMIVGFILSQSIKKIK"
     gene            21581..>21781
                     /locus_tag="VU534_001472"
     CDS             21581..>21781
                     /locus_tag="VU534_001472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HEU1514045.1"
                     /translation="MKLTYDDKVQIYELRKQGYSLEKLSNKFGINNSNIRYMIKLIDR
                     YGIEFVKKGKNRYYSPDLKQEMI"
BASE COUNT         6446 a         3860 c         4772 g         6703 t
ORIGIN      
        1 aaagactgca atctgtggat tgcagttttt tatacgatgg atctatcgta gatctgatgt
       61 gcaaggccta cgtgccgatc atctatcggt gaacccaaga gcgaccctca agcctgcttg
      121 gattgaggta atagattcaa atatctgtag ttagactatt tgaagtttga tgtaagaaag
      181 agaaagcgac agattgaagt aattttaact ctcttctatt gctagaacaa atggtcggat
      241 aggttggtag tttgaaaatg aagatgctat ctattgttaa atggaacata gtgttattta
      301 ttagaaaatc gtttggttta tttcttatca aatacgaaaa gcaacttaaa tatttcaact
      361 aaaatagatg ttatgaagaa aaggtaaaat gattttggca tagtgaggtt ctgttctatt
      421 tgatatcata tttttgataa aaacaaaaat gtccattgca aaggacaaaa tgcgaagtat
      481 attatttttt gaaagcgata taatggattc ataaaggagg tgtatcgtgt ctagaaaaca
      541 agaacaaatg gaaacgttgt tgctcctttt gcgagatagt aaggattata tatctgctaa
      601 agtattggga gaaaaattaa attgctctga taaaacggtt tatcgccttg tcaagggaat
      661 caacaaagat tgtccggtag aagcattcat tttatctgaa aaaggcagag gtttcaaatt
      721 aaatccaaga agttccctcg tggacgttga tgggaatttt acagaggctt ttgatcctga
      781 agtaaggcgt gaaaaattac tagaacgtct cttgttgact gctcctaagc cacattctat
      841 ttatgattta ggagaggaat tctacgtaag cgagtcagta gtactaaaag atcgtcagat
      901 attacaagag agtctagcaa tttatgggtt agatttaaaa atgagacaac gaaagctttt
      961 tattgatggg gatgaggctc aaattcgttc agccattcta aatctactgc caatgtttaa
     1021 tcagttggat ttagagcaaa ttacacagaa taaggttcag cctcttgacg gagaacttgc
     1081 tcacttttgt ttgggattac tgattacact tgagagagaa ttgggggtaa acattcccta
     1141 tccatataat ataaatattt tctctcacct gtatattttt atcagtagga atcgtcgtag
     1201 tactagtatt catgttgtag caccttcaaa acctactatt gttgatgaga aaatttacag
     1261 tgtctgtcaa aaaattattc aagaaattga acaatatttt aggatgaagg ttgatgcagt
     1321 tgagattgac tatctttatc aatacgttgt atcttcgaga ttgcaaaaac cattttcttc
     1381 cgggaagctt cctttttctc agcgagtttt agatgtcact cattactatt ttagccgtat
     1441 gtgtatggac aatagagaga ttgaaacgac agatcctgac tttgttgact tggcgagtca
     1501 tatcagtccc ttactgagga gattagataa tagagtacag attaagaata gtcttttatc
     1561 acaaattctt ttaacctatc ctaatctggt taaagagtta acaactattt ctaaagaagt
     1621 gagtctagta tttggttttg cttccttgag tctggacgag attggttttc tagtcttata
     1681 ttttgcacgg tttcaagaaa agcgagcacg tcctctaaaa acagtagtga tgtgtacatc
     1741 aggtgtcgga acttcagagc ttttacgagc acgattagaa aagcaatttt ctgaattgga
     1801 tattattgat gtagttgctt atcatcaatt agatgagctg ataaatctat atccagattt
     1861 agatttcatt gtgacgacgg tagctttgca ggaaccagca agtgtcccgt ttgtcctagt
     1921 tagtgttttt ctaaccgagg gtgataaaca acgtcttcaa gcaaaaattc aggagataaa
     1981 ctatgaataa tctttcgctt gtccttatgg atatatctgt tcaaaatcgt caagaagcct
     2041 acaaagaatt agcaaatcaa atcagccttc ttgtttctga agatacagaa aaaatagaag
     2101 agcttctata ttaccgtgag agacagggaa gtatagaggt tgctaaaggt gttcttctac
     2161 cacattgtga aggaaacttt caacatcatg tcttagtgat tactagatta aaatcaccta
     2221 tcagagaatg gtcgaaggat atccagtgtg ttgaccttat tatcggtttg gccattgcag
     2281 tatcacagga caagtcatgt attaaaacat tgatgagaag actagcagat gaatcattca
     2341 taaatcaatt aaaacagtta acaaaagaag aattacggga gataatatat ggaaatcaaa
     2401 gatattctta atgtgagtct gatccagacg gatttacaga tgcagagcaa agaagaggtt
     2461 tttgaggcat tagctcaact attggttgag acgggttatg tgtctgatag agaccaattt
     2521 atcgaaggtc tttatcagag agaggcagaa ggacagaccg gtattgggaa ttatattgct
     2581 attccccata gcaagagttc tgctgtggag aaggcggggg tagtcatagc tataaatcac
     2641 aatgagattc cttgggagac cattgatggg aaaggggtca aagtaattgt actctttgca
     2701 gttggtgatg atacagaagc tgctagggag catttgaaga ccttatcact ctttgctcga
     2761 aaacttggta atgacgaagt tgttgccaaa ttagttcggg ctcagacatc tgatgatgtg
     2821 attgcagctt tttgttaata agaaaaaatt ttggagggta tccgtatgaa aattgttggt
     2881 gttgcagctt gtactgtggg aattgcccac acttatattg cacaggaaaa attagagaat
     2941 gccgcaaagg tagctggaca tgtgattcat gttgagactc aggggacaat aggggtagaa
     3001 aatgaattga gtcaagagca gattgatgca gcggatgtag ttattttagc agttgatgtt
     3061 aagatttctg gtatggaacg ctttgagggt aaaaagatta tcaaggttcc aacagaagtg
     3121 gcagtcaaat ctcccaataa actgattgct aaagctgttg agattgttac gaaataactg
     3181 aaaatattta aggagaaaat atatgttgaa acacttaaac ttaaaaggtc acttattgac
     3241 agccatttcc tatatgattc caattgtttg tggtgcagga ttcttagttg ccattggttt
     3301 agcaatgggg ggtggtgttc ctgacgctct tgtagcagga aaattcacta tctgggatgc
     3361 tttagcaact atgggtggta aagcccttgg tctcttgcca gttgttattg ctacaggttt
     3421 gtcttactcg attgctggta agccagggat tgcaccaggt tttgttgttg gtctaattgc
     3481 caattctgtt ggttcagggt ttatcggtgg tatcttggga ggttatatag ctggtttctt
     3541 ggttcaagcg attattaaaa aggtcaaagt accaaactgg attaaaggtt taatgccaac
     3601 cttgattatt ccttttgtag cctctttggt aagtagtttg attatgattt atattattgg
     3661 agcgcctatc gcagccttta ccaactggtt gacgagctta ttacaaagct tgggaagtgc
     3721 ttcaaatggt ttgatggggg cagttattgg aattctcagt gctgttgact ttggtggccc
     3781 acttaataaa acagtctatg cgtttgtgtt gactttacag gctgaaggtg tgaaagaacc
     3841 attgactgct ttacaattgg tgaatactgc tacaccagtt ggatttggat tggcctattt
     3901 tatcgcgaaa ttactcaaaa aaaatatcta tactcaagag gaaatcgaaa cattgaaatc
     3961 ggctgttcct atggggattg tcaatattgt tgaaggtgta attccgattg ttatgaataa
     4021 cttggttcca ggtctcattg caacaggtat cggtggtgct gttggtggtg ctgtttcttt
     4081 gacaatgggt gctgattctg ctgtgccatt tggtggagtg cttatgttac caaccatgac
     4141 tcgtccagta gctggtattt gtgccttgtt agctaacatt gtagtcacag gacttgtcta
     4201 cgcgattttg aaaaaaccaa taaaacatgc agaaccagtt atgactgttg aagaagagat
     4261 tgatttgtca gatattgaaa ttttgtaaga gggtaacgat gtcaagaatt gaattttcac
     4321 catctttgat gaccatggat ttggacaaat tcaaagagca gattactttt ttgaatgata
     4381 aagtagcatc ttatcatatc gatattatgg atggccattt tgttcccaat attaccttgt
     4441 ctccttggtt cattcaagaa gttcaaaaaa ttagtgacac acctttatca gttcatctga
     4501 tggtcacaga cccaaccttt tgggtagatc aagttctcga tttacaatgt gagtatattt
     4561 gtattcatgc tgaagttctg aatggtcttg cttttcgttt gattgataaa attcatgatg
     4621 caggtctaaa ggctggtgtt gtccttaatc ctgaaacacc tgtttctaca atctttccct
     4681 acattgattt acttgacaaa gcaactatta tgactgtaga tccaggtttt gcaggacaac
     4741 gctttttgga gtctaccttg tataaaatcc aagaactccg tcagcttaga gttcagaatg
     4801 gttatcacta catcattgag atggatggtt cttcgagtcg taagactttc aaacaaattg
     4861 atgtggcagg accagatatt tatgttatag gtcgcagtgg attatttggt ttggatgacg
     4921 atattgccaa agcctgggat atctgttcta gagattacga agaaatgacc ggaaaaacaa
     4981 tgccaatcaa ataatggttt gagaagaaat ttattagtta ggaggaatat atgtcactac
     5041 aatcagttaa cgccattcgt tttcttggcg tagatgctat taacaaatct aattctggtc
     5101 acccgggaat tgtcatgggt gctgcgccaa tggcttatag cctatttaca aagcacctta
     5161 gaattacacc tgagcagcca aactggatta accgagatcg ctttatcttg tctgcgggtc
     5221 atggatcaat gctactgtat gctctcttgc atttaacagg gtataaggat gtatccatgg
     5281 acgagattaa aaatttccgg caatggggat ctaagacacc tggtcatcct gaagtgacgc
     5341 atacgtctgg tgtggatgcg acatctggtc cgcttggtca ggggatttct actgccgttg
     5401 gtttcgccca agcagagcgt tttttagctg ctaagtacaa caaagatggt ttccctattt
     5461 ttgaccatta tacttatgtt atcgctggag acggtgactt catggaagga gtgtctgcgg
     5521 aggcggcttc ttatgcaggt catcaagctt tagataagct tatcgtcctc tacgactcca
     5581 acgacatctg cttggatggt gagaccaaag atactttctc tgaaaatgtt cgcgtccgtt
     5641 acgatgctta tggttggcat acagttctgg tagaagatgg aacagattta gcagcaattt
     5701 ctacagcaat tgagacggcc aagttttctg gtaaaccgag tttgattgaa gtgaaaacgg
     5761 taattggtta cggctcaccc aataaaagtg gtacaaatgc tgttcatggt gcaccactag
     5821 gagcagaaga aacaggagca actcgtaagt ttttgggatg ggattacgat ccatttgaag
     5881 taccagagga agtatattct gatttcaaga caaatgtagc ggatcgtggt caggaggcat
     5941 acgatgcttg ggctagtttg gtgtctgatt acaaggttgc ttatcccgaa gttgctagtg
     6001 agattgacgc tattgtagct ggaaaatccc ctgtaaccat tactgaaaaa gacttccctg
     6061 tctatgagaa tggcttctct caagcaactc gtaattcgtc ccaagatgct attaatacag
     6121 cagcagtttt accaaccttc ttaggtggat cggcagactt agctcactct aacatgacct
     6181 acatcaaggc agatggctta caagataaat ataatccatt aaaccgcaat attcagtttg
     6241 gggtacgtga atttgccatg ggaacaatcc tcaatggaat ggctcttcat ggtggtttac
     6301 gagtttatgg cggaaccttc tttgttttct ctgactacgt caaagctgct attcggctat
     6361 cagccattca ggagttgcct gtaacttatg tctttaccca tgattcaatt gccgttggtg
     6421 aagatggtcc aactcatgaa ccagttgaac atttggcagg tttacgctca atgccaaact
     6481 tgactgttat ccgtccagcg gatgcccgtg aaactcaagc ggcttggcat catgccttga
     6541 ccagtaccac cactccaact gtcattgtct taacccgtca aaacttggta gttgaagaag
     6601 ggacagactt tggtaaggtc gctaaaggag cctacgtcgt gtatgatacc ccgggatttg
     6661 atactattat cattgctaca ggatctgagg tcaatctagc tatcaaagct gctaaggaat
     6721 tggttttaca aggtggtaaa gtacgtgtgg tatctatgcc ctcaaccgaa ctatttgatg
     6781 ctcaagatgc tacctacaag gaagacattt taccatctaa gactcgtcgt cgtgtggcca
     6841 ttgaaatggc agcgacccaa agttggtaca agtatgttgg tttggatggc gcggtcatcg
     6901 gtattgacat cttcggtgcg tctgccccag ctcagactgt gattgataat tatggattta
     6961 cggtagagaa tatcgttgct caagttaagt ccctatagaa accaattaca atgaagatac
     7021 agctgttgtc agactagcag atgtagtgat agacactaat cagatgattg gttatttaaa
     7081 aactgtaatg aaaatgtaat aatttatcta cgaaagttat agtagatagt atacacaata
     7141 gagtataccc tgaaacggtt gcgaagtacg ctaatcactt tgctactgat ctagatagtt
     7201 tctttaatca ataaacacag catccacaga ttgacttagg atattgtaag ttttttgaaa
     7261 gctagagaga aggtctctaa aattaaaaaa cgcatagtat aggatgttga aatgatgaac
     7321 tgcaccccaa aagttagaca gaaaaaaatc taacttttgg ggtgttttta ttatgaaatt
     7381 aacttatgat gataaagttc agttctatga acttagaaaa caaggatata tcttagagaa
     7441 gctttcaaat aaatttggga taaataattc taatcttagg tacatgatta aattgattga
     7501 tcgttacgga atagagttcg tcaaaaaagg gaaaaatcgt tactattctc ctgatttaaa
     7561 acaagaaatg attcataaag tctgacatga aggctggact aaagatagag tttctcttga
     7621 atacggtctc ccaagtcgta cgatacttct taactggcta gcacaataca ggaaaaacgg
     7681 gtatactatt gttgagaaaa caaaagggag agtacctgag agcggagaat gccatcctaa
     7741 aaaagttaag agaactccga ttgaaggagg aaaaagagaa ataagaaaga cagaaattgt
     7801 tcaagaatta atgactgagt tttcgttaga tcttcttcta aaagccatta aactagctcg
     7861 ttggacctac tactatcact tgaaacagct agataaacca gataaggacc aagagcttaa
     7921 agctgaaatt caatccatct ttatcgaaca caagggaaat tatgcttatc gccgggttca
     7981 tttagaacta agaaatcgtg cttatctggt aaatcataaa agagttcaag gcttgatgaa
     8041 agtactcaat ttacaagcta aaatgcgaca gaaacgaaaa tattcttctc ataaaggaga
     8101 cgttggtaag aaagcagaga atctcattca aggccaattt gaaggctcta aaacaatgga
     8161 aaagtgctac acagatgtga cagaatttgc cattccagca agtactcaaa aactttactt
     8221 atcaccagtt ttagatggct ttaacagcga aattattgct tttaatcttt cttgttcgcc
     8281 taatttagaa taagtacaaa caatgttgga acaggcattc aaagagaagc actatgagaa
     8341 tacgattctc catagtgacc aaggctggca ataccaacac gattcttatc atcggttcct
     8401 agagagtaag ggaattcaag catccatgtc acgcaagggc aacagcccag acaacggcat
     8461 gatggaatct ttctttggca ttttgaaatc ggagatgttt tatggttatg agaagaactt
     8521 tagatcttta gaaaaccttg aacaagctat tgtggactac attgattatt acaacaacaa
     8581 gagaattaag gtaaagctaa aaggacttag ccctgtgcaa tacagaacta aatccttcgg
     8641 ataaattaat tgtctaactt ttggggtgca gtacattttt ggtatatata aaatttgtag
     8701 gagctatatc tacaatttta tattcccagt ttatggatgt aacttactat attcacaatg
     8761 ttatccagtg ttttttctct aatatttaag gagtgttctg tttctcgaat aaattcttca
     8821 aagtttaacc cgtcaacttg ttcctgaaca agaaaataat catccacgat ataaaattca
     8881 tcagttaaat tagtagtata acttttatcg gctaattttt ttagcatgtg agcttcattt
     8941 tttatatcat caagagctgt ccattctcct tcagcatcat aattcacaaa aggtcttgac
     9001 tgcttgatga ttactttttg cccgtccgat tttctaattg cccgataaac atttccttta
     9061 tttgatctct taataatttt ttccattttg tatttattta ttgcagagtc cttacttgaa
     9121 acttcacatg tggtttgaaa ataaatcctt ttttcttctt ctgaaaataa atccattttc
     9181 cagctaggaa gactagggaa attttgtctc ttatcttcta catagttctt ccttttttca
     9241 tctagcaata aatagatgac ttttttattt ttttcatcat aagcttgttt ttttaaaaaa
     9301 gccccatatc tataatgaac tggagaatgc attccacatt gatagtcaga tagtattttt
     9361 ggagccttaa attctgacag tctattcgta agattacaaa tcatactctt agcttcagat
     9421 tctgacttag gatatagagt tataaatttg ttagcagtag ggctcatttc cctaggggaa
     9481 ttaatttttt ttaattcctc taaattttta acaactttaa agctacaatt atttagttgg
     9541 gatagtttat acacaatctt aaaaatattt acagcgtctt ttatttggga gcttatgtgt
     9601 attttccacc cttgtgcagg catcttatct gataaataat agtaattcca aatatcaccc
     9661 tgttggaaat ttttatcaca ttttaaacat tctttctcta ataaatccat aacaaactcc
     9721 taattattaa aataggctag agacacagca ctagcctatt ccgtaagtaa agctacttat
     9781 tttatataaa atataactag cgacctgtaa ttaaacaagt aaaagaacaa tacttaggga
     9841 gacctgtgac aatgatatct tcctctggaa gtagttctaa ttcaaacaat gtttgttcca
     9901 tgactgtatc ctcctgttat gataaattcc agaaagcata gagcaaattc gtggttcgtc
     9961 tgactaaatt tcttatctga acaccacctt caaatacaaa ttttagtcaa acttttattt
    10021 tttctaactt tctaattata ttctaccatg tgtttttata tgtcaagaat tttctgaata
    10081 aactgtttat tttttatttt ttgacatttt tgcaaattgt ttaaaatctt tcaattggat
    10141 tcacttatta ctttaggaca ttgaaacttc tttcgccaga ggtgcttata ttactgggaa
    10201 gttgaagatt gaaatgtggt ataataagag gtaatagagt tttggaaagt gagagaagat
    10261 gatttcaaag agattagaat tggtagcttc ctttgtgtca cagggggcta ttttactaga
    10321 tgtgggaagt gaccatgctt atctgcctat cgagttggtt gagagaggcc aaatcaaaag
    10381 cgctattgca ggtgaggtgg tggaaggtcc ctatcagtct gcggttaaaa atgttgaggc
    10441 tcacggccta aaggagaaaa tccaagtccg tttagccaat ggcttggcag cttttgaaga
    10501 gactgaccaa gtgtctgtca ttaccattgc tggcatgggt ggtcgtttga ttgctaggat
    10561 tttagaagaa ggtttgggga agttagctaa tgtagagcgt ttgatcctcc agcccaataa
    10621 tcgtgaagac gacttgcgta tctggctaca ggatcatgga ttccagattg tagcagaaag
    10681 catcttagaa gaagctggaa agttttatga gattttggtg gtggaagcag gacaaatgaa
    10741 gctatcagcc agtgatgttc gctttggtcc cttcttgtcc aaagaagtca gtccagtatt
    10801 tgtccaaaaa tggcaaaaag aagctgagaa gctagagttc gccctcggac aaatcccaga
    10861 aaaaaatctg gaagaacgtc aagttctagt agataagatt caagctatca aggaggtgct
    10921 ccatgttagc aagtgaagtg atccaagctt atgaagcctt ttgccctcag gaattttcta
    10981 tggagggaga cagccgtggt ctgcaaattg gcactttaga caagggtatc caaagggtca
    11041 tggttgccct cgatattcgt gaagagacag tggcagaggc cattgaaaag ggtgtggact
    11101 tgattatcgt caagcacgcg cctatctttc gtcctatcaa ggacttgctt gccagccgtc
    11161 cgcaaaatca gatttacatc gacctgatta agcatgatat cgcagtttat gtcagccata
    11221 ccaatattga tatcgttgaa aatgggctca atgactggtt ttgtcagatg ctaggaatcg
    11281 aggagacgac ttatctgcag gaaacaggtc cagaacgtgg aattggacgt attgggaata
    11341 ttcagcctca gacattttgg gaattggccc aacaggtcaa gcaagtcttt gacctagata
    11401 gccttcgaat ggtgcattat caagaggatg atttgcagaa gcctatttca agagtagcaa
    11461 tttgtggtgg aagcgggcag tctttctata aggatgcttt ggcaaagggg gcagatgtct
    11521 atatcactgg tgatatctac taccatactg ctcaggatat gctatctgat gggttgcttg
    11581 cattggaccc aggtcactat atcgaagtga tttttgtaga aaaaatcgca gcacttctta
    11641 gtcaatggaa ggaagataag gggtggtcta ttgatatctt gcctagtcag gcatcaacca
    11701 atcctttcca tcatatctag ttagaaagtg aagacaatga aaaaagttgc cattattgga
    11761 gcaggaattg tgggagcaac agctgcctac tacctctcga gagaaagtga cctagaggtg
    11821 accgtttttg accatgagca aggtcaagcc accaaggccg cagcaggaat tatcagtcct
    11881 tggttttcca aacgccgtaa taaagcctgg tacaagatgg cgcgcttggg ggctgatttt
    11941 tatgtggatt tattagctga tttagagaaa tcaggacaag aaatcgactt ttaccagcgt
    12001 tcgggagtct ttctcttgaa aaaggatgaa tccaatttgg aagaacttta tcaactggcc
    12061 ctccagcgca gagaagaatc tcccttgata gggcaattag ccattctgaa ccaagcctca
    12121 gctaatgaat tattccctgg tttgcaggga tttgaccgcc tgctctatgc ttctggtgga
    12181 gcgagagtag atggccaact tttagtgact cgtttgctgg aagtcagtca tgtcaagctg
    12241 gtcaaagaaa aagtgactct gacaccgtta gcatcaggct accagattgg tgaagaggag
    12301 tttgagcagg ttattttggc gacgggagct tggttggggg acatgttaga gcctttaggt
    12361 tatgaagtgg atgtccgtcc tcaaaaagga caactacgag attatcagct tgcccaagac
    12421 atggaagatt accctgttgt catgccagaa ggggagtggg atttgattcc ctttgcaggt
    12481 gggaaattat ccttaggcgc tacccacgaa aatgacatgg gatttgattt gacggtagat
    12541 gaaaccttgc tccaacaaat ggaggaggcc accttgactc actatctgat tttggctgaa
    12601 gctacttcaa aatctgagcg tgttggaatc cgtgcctaca ccagtgattt ctctcctttc
    12661 tttgggcagg tgcctgactt aactggtgtc tatgcagcca gtggactagg ttcatcaggc
    12721 ctcacaactg gtcctatcat tggttaccat ctagcccaac tgatccaaga caaggagttg
    12781 accttggacc ctctaaatta cccaattgaa aactatgtca aacgagtaaa aagcgaataa
    12841 tactcaataa aaatcaaaga acaaactagg aaactagccg cgggttactc aaagcactgc
    12901 tttgaggttg tggatagaac tgacgaagtc agctcaaaac actgttttga ggttgtggat
    12961 agaactgacg aagtcagtaa ccatacccat ggcaaggcga cgttgacgta gtttgaattg
    13021 gattttcgaa gagtataagc attttactga aattttatca ggtagtttag gatggcaaat
    13081 gacattccct gtcaaaaatg gtaaaataag aaaaaataat ctgagaatcg aggaaaaaag
    13141 atgcaagaaa agattttggt aactggtggt gccggtttta ttggaaccca cactgttatt
    13201 gaattgatcc aagcaggtca tcaagttgtt gtggtggata atcttgtcaa tagcaatcgt
    13261 aagagtttag aagttgttga aggaatcaca ggagttgaga ttcctttcta tgaggcagat
    13321 attcgtgaca cagataccct cagagatatt ttcaagcagg aagaaccgac tggtgtcatt
    13381 cactttgctg gtttgaaggc tgttggcgaa tcaacacgta tccctcttgc ctactatgac
    13441 aacaatatcg ctggaactgt cagccttttg aaagccatgg aagaaaacaa ctgtaaaaac
    13501 atcatcttca gttcttctgc gacagtttac ggggatccgc acacagtgcc catcttggaa
    13561 gatttcccac tttcagtgac caacccatac ggtcgtacta agctcatgct agaggaaatt
    13621 ttgactgata tttacaaagc agactcagaa tggaatgttg tcttgcttcg ttactttaac
    13681 ccaatcggag cccatgagag tggtgatttg ggagaaaatc caaacggtat tccaaacaat
    13741 ctcttgccat atgtgactca agtagccgtt ggaaaattag agcaagtgca agtgtttgga
    13801 gacgattacg atacggaaga tggaacaggt gttcgtgact atatccacgt tgtcgatttg
    13861 gctaagggtc acgttgcagc tttgaaaaaa atccaaaaag gttcaggact aaacgtttat
    13921 aaccttggaa ctggtaaagg ttactcagtt cttgaaatta tccaaaacat ggaaaaagcg
    13981 gtgggccgtc ctattcctta ccgcatcgta gaacgtcgcc caggtgatat cgctgcctgc
    14041 tactcagacc cggcaaaagc taaagcagaa ctcggttggg aagcagaact cgacatcacc
    14101 caaatgtgtg aagacgcatg gcgttggcaa agcaagcatc caaatggatt tgaagactaa
    14161 gatgatgatt tcaatcatcg tcccttgttt aaacgaagag gaagtacttc ctctttttta
    14221 tcaggctctg gaagctttac ttccagattt ggaaacagaa atcgagtatg tctttgtcga
    14281 tgatggatca agtgatggga ccttggaact cttaaaggcc tatcgggagc aaaatccggc
    14341 agtccattat atttctttct ctcgaaattt tggcaaagaa gcagcccttt atgcaggctt
    14401 gcaatatgcg acaggagatt tggtggtggt gatggatgca gacctccaag atcctcctag
    14461 tatgttgttt gagatgaaaa atgtattaga caaaaatgta gacttggact gcgttgggac
    14521 acggagaact agtcgggagg gagaaccctt ctttcgcagt ttctgtgctg ttctctttta
    14581 tcgcctcatg caaaaaatca gcccagtagc tctgccgtcg ggtgtccgtg attttcgtat
    14641 gatgagaagg tctgtagtcg atgccatttt aagcttgacc gagtccaatc gtttttcaaa
    14701 ggggctcttc gcctgggtgg gtttcaaaac ctactatttg gactatccaa atgtcgaaag
    14761 gcaggctggc aagacaagtt ggagttttag gcaactcttt ttctactcca ttgaagggat
    14821 tattaatttt tcagattttc ccttgattat agcctttgta gctggtctcc tatcttgttt
    14881 tctttctctg ctgatgacct tttttgttgt ggttcggacc ctcattttgg gcaatccgac
    14941 atctggttgg acctctctga tggctgttat tctctttctt ggaggcattc aactcttgac
    15001 cattgggatt ctcggcaagt atatcagtaa gatttattta gagactaaaa aaagaccact
    15061 ttatcttatc aaagaaaaaa gtgaccttcc tgattttaca gaaaaaaata aagtgaaaag
    15121 actataattt tacatggaaa tgtgctaaac tagagggagt ggattatcgc cattgattta
    15181 ggcttcctgg tttccaatca gggcgcgagt tgggcaattt ttaacagcct ctaagatatc
    15241 ctgactagga gaaatttctt tttccagttg gtcagggtca tcgtaaaaac gcacgattcc
    15301 attatcgtgg taatcaaata aatcagaata agtttggcaa agcccacagg cgatacatcg
    15361 ttcaggtata agtgtgattt tcatgttcat atttatattg taataagaaa agtaaaaaaa
    15421 aacaaggagt aaggtatggc aaaagaaccg tggcaagaag atatctatga tcaagaagaa
    15481 tcaagagcag agcgtcggca tcgaaaccac ggaggggctg ataggatggc taatcgtatt
    15541 ttgacgatcc tagctagtat tttctttgta attgtggtgg tgatggtcat cgttctcatc
    15601 tatctatcat cgggggggag taatcgcaca gcagccttaa aaggctttca tgattctgat
    15661 gccagtgtag tacaaatctc atcttcaagt agttctcagc ctgagcagag ttcagagcca
    15721 gaatctactt ctagtagttc agaagaagct gctaatcctg aaggaacgat taaagttctc
    15781 gcaggagaag gggaagcagc tattgccgct cgtgcaggaa tctccattgc tcagttagag
    15841 gccttgaatc ctgggcacat ggctacagga tcttggtttg ctaatccagg tgatgttata
    15901 aaaataaaat aggagccgat atgaaaacaa ttcaaattgc tattgatggt cctgcttcca
    15961 gcggtaagag tacggtcgca aagattattg ctaaggattt tggattcacc taccttgata
    16021 caggagctat gtatcgtgca gcgacctata tggctcttaa gaaccaatta ggagttgaag
    16081 aagtcgaagc ccttctagcc ttgttggacc agcatccaat cagctttgga cgttcagaaa
    16141 ctggagacca gcttgttttt gtaggagatg tggatattac ccatcctatc cgtgaaaatg
    16201 aagtgaccaa tcatgtttct gctattgcag caattcctca agtgcgtgag aaactggttt
    16261 ctctccaaca agaaattgcc cagcaaggcg ggattgtcat ggatggtcgc gatattggaa
    16321 ctgttgtatt gccacaagca gaattgaaaa ttttcctagt agcttctgtt gatgagagag
    16381 cagagcgtcg ttacaaggaa aatattgcca agggaattga aacagacctt gaaaccctaa
    16441 aaaaggaaat tgctgcgcgt gactacaagg atagtcatcg tgagacttct cctctcaaac
    16501 aagcagagga tgctgtctac cttgatacaa ctggtttgaa cattcaagaa gtagttgaaa
    16561 aaatcaaagc agaagctgaa aaaagaatgt aaatgtagaa aagccgatag attgatatcg
    16621 gtttttttct aaatttgtca aaatgctgat tttagggtat aatagttgct gttcgagaaa
    16681 ttttgatttt caaagaatag tgaatgatga taaggagaaa ccatgaacaa tttaccaaat
    16741 tgtccaaaat gtaactcaga gtatgtctac gaagacggtg ccctactggt ttgcccagag
    16801 tgtgctcatg agtggaatcc tgctgaagtt gcagaagtag aagaaggtct tgtcgctatc
    16861 gatgccaacg gaaataaatt ggctgatggt gatacagtaa ctctcatcaa ggacttgaaa
    16921 gtaaaaggtg cgccaaaaga tttgaaacaa gggacgcgcg tgaaaaatat ccgcatcgta
    16981 gaaggcgacc acaatatcga ctgtaagatt gatggttttg gtgccatgaa acttaaatca
    17041 gagtttgtga ggaagattta agcatgtcaa aacactataa acttgtattt tatagccgta
    17101 tcttcttgtt tctagcggct tttacgggag tttatcttga aattactaag catggtggtt
    17161 ttgggatgct tctctattac acggttctgt ccaacctctt ggtaactatt tttacccttt
    17221 atcttctaaa ggttatgagc cgtgtaggtg aaaattggca aaggccaagt ctcttgcgct
    17281 taaaaggtgg ggtcaccatg agtatcatga ttacctgtgt gatttaccat ttcctcttgg
    17341 cgcccattgc gactaatttc tataccctag aaaatttcct ttgccactat atcgttccca
    17401 tctggttttt agcggatacc ctcttttttg acaaacaggg tcaatacaag atttgggatc
    17461 cagcagtgtg gaccatttta ccctttctgt atatgatgtt tgctcttttt aatggcttgg
    17521 ttctaaaact caatattcca aatgccaagg ataatccttt cccttacttc tttttgaatg
    17581 tgaacaaggg ttggaatgtt gtgtttaagt ggtgtctgat tatctttgtt gcctatatgg
    17641 tagcaggatt tattttctac tttatcaagc aaatcaagag aaagtcatcc taatactctt
    17701 cgaaaatctc ttcaaaccac gtcagtttcc atctgcaacc tcaaaacact gttttgaaca
    17761 acctgcggct agcttcctag tttgctcttt gattttcatt gagtataaga tacaagggat
    17821 tcattttcga atttaagaag gagtctacaa accaatgagg cttcttcttt tcttgcttat
    17881 ttgataacta tcaaaaaagt agaagattaa gagaaatata gaaagagatt tcatgaaaca
    17941 atttttagaa cgggccagca ttttggctct ctccctcgtt ttgattacct ccttttccat
    18001 ttcgagtgcc ctaccagcca tgtttgacta ttatcagggt tattctaagg aacaaattga
    18061 gctcttggtg agcttgcctt cctttggaat catgatgatg ttactgctaa atggtttctt
    18121 agaaaaaata tttcctgagc gcttacagat tagtttgggc ttgctgattt tatcattgag
    18181 cggtacagct cccttctggt accaagccta tccctttgtc tttggaacac ggcttctctt
    18241 tggtttgggt cttgggatga tcaatgccaa ggccatttct attatcagtg aacgctacca
    18301 aggaaaaagg cgaattcaga tgttagggct acgcgcttct gcagaggtcg ttggagcttc
    18361 tctcattacc ttggccgtcg gtcagttgtt ggcctttggt tggacagcta tctttctagc
    18421 ctatagtgct ggatttttgg tgctgcccct ttatctgctc tttgtccctt atggaaaatc
    18481 aaagaaagaa gtcaagaaaa gagcgaagga agcaagtcgt ttaactcgag aaatgaaagg
    18541 cttgattttt accttagcta tcgaagcggc agttgtagtt tgtaccaata cagctattac
    18601 catccgtatt ccaagtttga tggtggaaag aggattgggg gatgcccagt tatctagttt
    18661 tgttcttagt atcatgcagt tgatcgggat tgtggctggg gtgagttttt ctttcttgat
    18721 ttctatcttt aaagagaaac tgctcctctg gtctggtatt acctttggct tggggcaaat
    18781 cgtgattgcc ttgtcttcat ccttgtgggt ggtagtagca ggaagtgttc tggctggatt
    18841 tgcctatagt gtagtcttga cgacggtctt tcaacttgtc tctgaacgaa ttccagctaa
    18901 actcctcaat caagcaactt catttgctgt attaggctgt agtttcggag cctttacgac
    18961 cccattcgtt ctaggtgcaa ttggcttact aactcacaat gggatgttgg tctttagtat
    19021 cttaggaggt tggttgattg taatctctat ctttgtcatg tacctacttc agaagagagc
    19081 ttaggattga ttcctaagtt tttcttttga tactcaatga aaatcaaaga gcaaactata
    19141 gttgattgag tttggaatag tacgctgtag ctgctaaaat atttctagaa attaatttga
    19201 ctttcctaat agagttgttc atatcttatt tcaatctact atagaaagct agccgcaggt
    19261 tgctcaaaat agtgtgttga ggttgcagat ggaaactgac gtggtttgaa gagattttcg
    19321 aagagtatga gatttttata cccatacaat atttgtttta ggtccttgtt tacagactaa
    19381 tttcttgata aaatagaggc tatgacgaga tataaagcaa ctatttccta tgatggttat
    19441 gcctttgctg gctttcagcg ccagcctcat gcgcgtagcg ttcaggaaga aattgaaaaa
    19501 accttgacca gattaaataa agggcaagcc attactgttc acggtgctgg taggacagat
    19561 agtggggttc atgccctggg acaggtgatt cattttgacc tgccttatca gatggatgag
    19621 gagaaactcc gttttgcctt ggatacccag tctcctgaag atattgatgt gatttcgatt
    19681 gagcttgtgg cagatgattt tcattgccgt tatgccaagc atagcaagac ctatgagttt
    19741 actgtggata gaggacgtcc caaaaatccg atgcgccgtc actatgccac ccactttccc
    19801 tacccactcg atgtggaacg aatgcagatt gcaatcaaaa agctagaggg aacccatgat
    19861 tttaccggtt ttacagcctc tgggactagt gtagaggata aggttcgcac catcacagaa
    19921 gctagtttaa tagtcgatga gacaggacaa tttttgacct ttaccttttc aggaaatggt
    19981 ttcttgtata aacagattcg caatatggtg gggactcttc tcaaaatcgg taacaaccgc
    20041 atgccagtag agcagattga tctcatcttg gagaagaagg acaggcaact tgcaggtccc
    20101 actgcagcac caaatggttt gtatttaaag gagattcgtt atgaagaata atcgtatttt
    20161 agcactttct ggaaatgata tttttagtgg tggtggactg tcagctgatt tggctaccta
    20221 taccttgaac ggcttgcatg ggtttgtagc agtgacttgt ttgacagcct tgacagaaaa
    20281 aggatttgaa gtctttccaa ctgatgatac catttttcaa catgaattag atagcttgcg
    20341 tgatgtggaa tttgggggaa ttaagattgg tcttctccct actgtcagcg tggctgagaa
    20401 ggccttggac tttatcaaac aacgcccagg agtacctgtg gtgttggatc ctgtcttggt
    20461 ctgcaaggaa acgcatgatg tagctgtcag tgagctctgc caagagttga ttcgcttttt
    20521 cccttatgtc agtgtgatta cgcctaatct cccagaagca gaattattat ccggtcagga
    20581 aattaaaacc ttggaagaca tgaaaactgc agcgcagaaa ttgcatgatt taggagcgcc
    20641 agcagtcatt atcaagggag gcaatcgtct tagtcaggac aaggctgtgg atgtctttta
    20701 tgatggacag acctttacta tcctagaaaa tccagttatc caaggccaaa atgctggtgc
    20761 aggttgtacc tttgcctcta gcattgccag tcacctggtt aaaggtgata aacttttgcc
    20821 agcagtagaa agctctaagg ctttcgttta tcgtgctatt gcacaagcag atcagtatgg
    20881 agtaagacaa tatgaagcaa acaaaaacaa ctaaaatcgc ccttgtatcc ctattaaccg
    20941 ccctttctgt ggttctaggt tatttcttaa aaatcccaac acctacagga attctaactc
    21001 ttttagatgc tggtgtcttc tttgcggcct tttactttgg tagtcgtgaa ggagcggtag
    21061 tcggaggact agcaagtttc ttgattgacc tcttatcagg ctaccctcag tggatgttct
    21121 ttagcttggt caaccatggc ttgcagggat ttttcgcagg atttaaagga aaaagtcagt
    21181 ggttaggcct tattttagca actattgcca tggtaggagg ctacgccttg ggttctgctt
    21241 tgatgaatgg ctgggcagca gccctcccag aaattctacc gaattttatg caaaatatgg
    21301 tagggatgat tgtaggattt attcttagtc aaagtatcaa gaagattaag taatactctt
    21361 cgaaaatctc ttcaaaccac gtcagcttcc atctgcaacc tcaaaacact gttttgagca
    21421 gcctgaggct agctttctag tttgcacttt gattttcatt gagtataaag aggttgagta
    21481 aaaagtattt caaataagaa aaacgcatag tatcaggtgt tgaatgaact gccccccaaa
    21541 agttagacag aaaaaatcta acttttgggg tgtttttatt atgaaactaa cttatgatga
    21601 taaagttcag atctatgaac ttagaaaaca aggatatagc ttagagaagc tttcaaataa
    21661 atttgggata aacaattcta atattaggta catgattaaa ttgattgatc gttacggaat
    21721 agagttcgtc aaaaaaggaa aaaatcgtta ctattctcct gatttaaaac aagaaatgat
    21781 t
//
LOCUS       DAVFER010000036        21439 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1105170250
            SAMEA2167659-rid19724873.denovo.036, whole genome shotgun sequence.
ACCESSION   DAVFER010000036 DAVFER010000000
VERSION     DAVFER010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2167659
            Sequence Read Archive: ERR388902
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21439)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21439)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928716.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928716.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 04:07:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,118
            CDSs (total)                      :: 2,073
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 120
            CDSs (without protein)            :: 120
            Pseudo Genes (ambiguous residues) :: 0 of 120
            Pseudo Genes (frameshifted)       :: 67 of 120
            Pseudo Genes (incomplete)         :: 47 of 120
            Pseudo Genes (internal stop)      :: 34 of 120
            Pseudo Genes (multiple problems)  :: 23 of 120
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21439
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2167659-rid19724873.denovo.036"
                     /strain="1105170250"
                     /db_xref="taxon:1313"
     gene            complement(229..1149)
                     /gene="cysK"
                     /locus_tag="VU534_001473"
     CDS             complement(229..1149)
                     /gene="cysK"
                     /locus_tag="VU534_001473"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000029859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HEU1514046.1"
                     /translation="MSIYNNITELIGQTPIVKLNNIVPEGAADVYIKLEAFNPGSSVK
                     DRIALSMIEKAEQDGILKPGSTIVEATSGNTGIGLSWVGAAKGYKVVIVMPETMSVER
                     RKIIQAYGAELVLTPGSEGMKGAIAKAQEIAAERDGFLPLQFDNPANPEVHERTTGAE
                     ILAAFGKDGLDAFVAGVGTGGTISGVSHALKSENSNIQVFAVEADESAILSGEKPGPH
                     KIQGISAGFIPDTLDTKAYDGIVRVTSDDALALGREIGGKEGFLVGISSAAAIYGAIE
                     VAKKLGTGKKVLALAPDNGERYLSTALYEL"
     gene            complement(1398..2033)
                     /locus_tag="VU534_001474"
     CDS             complement(1398..2033)
                     /locus_tag="VU534_001474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000395753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HEU1514047.1"
                     /translation="MEFRTIKEDGQVQEEIKKSRFICHAKRVYSEEEARDFITAIKKE
                     HYKATHNCSAFIIGERSEIKRTSDDGEPSGTAGVPMLGVLENHNLTNVCVVVTRYFGG
                     IKLGAGGLIRAYAGSVALAVKEIGIIEIKEQAGIAIQMSYAQYQEYSNFLKEHGLMEL
                     DTNFTDQVDTMIYVDKEEKETIKAALVEFFNGKVTLTDQGLREVEVPVNLV"
     gene            2089..3387
                     /locus_tag="VU534_001475"
     CDS             2089..3387
                     /locus_tag="VU534_001475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000867598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEU1514048.1"
                     /translation="MKVNLDYLGRLFTENELTEEERQLAEKLPAMRKEKGKLFCQRCN
                     STILEEWYLPIGAYYCRECLLMKRVRSDQTLYYFPQEDFPKQDVLKWRGQLTPFQEKV
                     SEGLLQVVDKQKPTLVHAVTGAGKTEMIYQVVAKVINAGGAVCLASPRIDVCLELYKR
                     LQQDFSCGIALLHGESEPYFRTPLVVATTHQLLKFYQAFDLLIVDEVDAFPYVDNPML
                     YHAVKNSVKENGLRIFLTATSTNELDKKVRLGELKRLNLPRRFHGNPLIIPKPIWLSD
                     FNRYLDKNRLSPKLKSYIEKQRKTAYPLLIFASEIKKGEQLAEILQEQFPNEKIGFVS
                     SVTEDRLEQVQAFRDGELTILISTTILERGVTFPCVDVFVVEANHRLFTKSSLIQIGG
                     RVGRSMDRPTGDLLFFHDGLNASIKKAIKEIQMMNKEAGL"
     gene            3384..4046
                     /locus_tag="VU534_001476"
     CDS             3384..4046
                     /locus_tag="VU534_001476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HEU1514049.1"
                     /translation="MKCLLCGQTMKTVLTFSSLLLLRNDDSCLCSDCDSTFERIGEEN
                     CPNCMKTELSTKCQDCQLWCKEGVEVSHRAIFTYNQAMKDFFSRYKFDGDFLLRKVFA
                     SFLSEELKKYKEYQFVVIPLSPDRYANRGFNQVEGLVEAAGFEYLDLLEKREERASSS
                     KNRSERLGTELPFFIKSGVTIPKKILLIDDIYTTGATINRVKKLLEEAGAKDVKTFSL
                     VR"
     gene            4126..4674
                     /gene="raiA"
                     /locus_tag="VU534_001477"
     CDS             4126..4674
                     /gene="raiA"
                     /locus_tag="VU534_001477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000599099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HEU1514050.1"
                     /translation="MIKYSIRGENLEVTEAIRDYVVSKLEKIEKYFQPEQELDARINL
                     KVYREKTAKVEVTIPLGSITLRAEDVSQDMYGSIDLVTDKIERQIRKNKTKIERKNKN
                     KVATGQLFTDALVEDSNIVQSKVVRSKQIDLKPMDLEEAILQMDLLGHDFFIYVDVED
                     QTTNVIYRREDGEIGLLEVKES"
     gene            4810..6783
                     /locus_tag="VU534_001478"
     CDS             4810..6783
                     /locus_tag="VU534_001478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HEU1514051.1"
                     /translation="MKKFYVSPIFPILVGLIAFGVLSTFIIFVNNNLLTVLILFLFVG
                     GYVFLFKKLRVHYTRSDVEQIQYVNHQAEESLTALLEQMPVGVMKLNLSSGEVEWFNP
                     YAELILTKEDGDFDLEAVQTIIKASVGNPSTYAKLGEKRYAVHMDASSGVLYFVDVSR
                     EQAITDELVTSRPVIGIVSVDNYDDLEDETSESDISQINSFVANFISEFSEKHMMFSR
                     RVSMDRFYLFTDYTVLEGLMNDKFSVIDAFREESKQRQLPLTLSMGFSYGDGNHDEIG
                     KVALLNLNLAEVRGGDQVVVKENDETKNPVYFGGGSAASIKRTRTRTRAMMTAISDKI
                     RSVDQVFVVGHKNLDMDALGSAVGMQLFARNVIENSYALYDEEQMSPDIERAVSFIEK
                     EGVTKLLSVKDAMGMVTNRSLLILVDHSKTALTLSKEFYDLFTQTIVIDHHRRDQDFP
                     DNAVITYIESGASSASELVTELIQFQNSKKNRLSRMQASVLMAGMMLDTKNFTSRVTS
                     RTFDVASYLRTRGSDSIAIQEIAATDFEEYREVNELILQGRKLGSDVLIAEAKDMKCY
                     DTVVISKAADAMLAMSGIEASFVLAKNTQGFISISARSRSKLNVQRIMEELGGGGHFN
                     LAAAQIKDVTLSEAGEKLTEIVLNEMKEKEKEE"
     gene            6780..7232
                     /gene="rplI"
                     /locus_tag="VU534_001479"
     CDS             6780..7232
                     /gene="rplI"
                     /locus_tag="VU534_001479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HEU1514052.1"
                     /translation="MKVIFLADVKGKGKKGEIKEVPTGYAQNFLIKKNLAKEATAQAV
                     GELRGKQKSEEKAHAEMIAEGKAIKAQLEAEETVVEFVEKVGPDGRTFGSITNKKIAE
                     ELQKQFGIKIDKRHIQVQAPIRAVGLIDVPVKIYQDITSVINLRVKEG"
     gene            7276..8628
                     /gene="dnaB"
                     /locus_tag="VU534_001480"
     CDS             7276..8628
                     /gene="dnaB"
                     /locus_tag="VU534_001480"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HEU1514053.1"
                     /translation="MAEVEELRVQPQDILAEQSVLGAIFIDESKLVFVREYIESRDFF
                     KYAHRLIFQAMVDLSDRGDAIDATTVRTILDNQGDLQNIGGLSYLVEIVNSVPTSANA
                     EYYAKIVAEKAMLRRLIAKLTESVNQAYEASQPADEIIAQAEKGLIDVSENANRSGFK
                     NIRDVLNLNFGNLEARSQQTTDITGIATGYRDLDHMTTGLHEEELIILAARPAVGKTA
                     FALNIAQNIGTKLDKTVAIFSLEMGAESLVDRMLAAEGLVESHSIRTGQLTDEEWQKY
                     TIAQGNLANASIYIDDTPGIRITEIRSRSRKLAQETGNLGLILIDYLQLITGTGRENR
                     QQEVSEISRQLKILAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIV
                     AFLYRDDYYERGGEEEEGIPNNKVEVIIEKNRSGARGTVELIFQKEYNKFSSISKREA
                     "
     gene            8630..8896
                     /locus_tag="VU534_001481"
     CDS             8630..8896
                     /locus_tag="VU534_001481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001278167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1514054.1"
                     /translation="MSDAFTDVAKMKKIKEEIKAHEGQVVEMTLENGRKRQKNRLGKL
                     IEVYPSLFIVEFGDVEGDKQVNVYVESFTYSDILTEKNLIHYLD"
     gene            8985..10331
                     /gene="cbpD"
                     /locus_tag="VU534_001482"
     CDS             8985..10331
                     /gene="cbpD"
                     /locus_tag="VU534_001482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline binding-anchored murein hydrolase CbpD"
                     /protein_id="HEU1514055.1"
                     /translation="MKILPFIARGTSYYLKMSVKKLVPFLVVGLMLAAGDSVYAYSRG
                     NGSIARGDDYPAYYKNGSQEIDQWRMYSRQCTSFVAFRLSNVNGFEIPAAYGNANEWG
                     HRARREGYRVDNTPTIGSITWSTAGTYGHVAWVSNVMGDQIEIEEYNYGYTESYNKRV
                     IKANTMTGFIHFKDLDGGSVGNSQSSTSTGGTHYFKTKSAIKTEPLASGTVIDYYYPG
                     EKVHYDQILEKDGYKWLSYTAYNGSYRYVQLEAVNKNPLGNSVLSSTGGTHYFKTKSA
                     IKTEPLVSATVIDYYYPGEKVHYDQILEKDGYKWLSYTAYNGSRRYIQLEGVTSSQNY
                     QNQSGNISSYGSHSSSTVGWKKINGSWYHFKSNGSKSTGWLKDGSSWYYLKLSGEMQT
                     GWLKENGLWYYLGSSGAMKTGWYQVSGKWYYSYSSGALAVNTTVDGYRVNSDGERV"
     regulatory      10414..10516
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            10587..10877
                     /locus_tag="VU534_001483"
     CDS             10587..10877
                     /locus_tag="VU534_001483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000647657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine-binding protein"
                     /protein_id="HEU1514056.1"
                     /translation="MKASIALQVLPLVQGIDRIAVIDQVIAYLQTQEVTMVVTPFETV
                     LEGEFDELMRILKEALEVAGQEADNVFANVKINVGEILSIDEKLEKYTETTH"
     gene            10840..11598
                     /locus_tag="VU534_001484"
     CDS             10840..11598
                     /locus_tag="VU534_001484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009013602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU1514057.1"
                     /translation="MRNLRSILRRHISLLGFLGVLSIWQLAGFLKLLPKFILPTPLEI
                     LQPFVRDREFLWHHSWATLRVALLGLILGVLIACLMAVLMDSLTWLNDLIYPMMVVIQ
                     TIPTIAIAPILVLWLGYGILPKIVLIILTTTFPIIVSILDGFRHCDKDMLTLFSLMRA
                     KPWQILWHFKIPVSLPYFYAGLRVSVSYAFITTVVSEWLGGFEGLGVYMIQSKKLFQY
                     DTMFAIIILVSIISLLGMKLVDISEKYVIKWKRS"
     gene            11637..12644
                     /locus_tag="VU534_001485"
     CDS             11637..12644
                     /locus_tag="VU534_001485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEU1514058.1"
                     /translation="MKKTWKVFLTLVTALVAVVLVACGQGTASKDNKEAELKKVDFIL
                     DWTPNTNHTGLYVAKEKGYFKEAGVDVDLKLPPEESSSDLVINGKAPFAVYFQDYMAK
                     KLEKGAGITAVAAIVEHNTSGIISRKSDNVSSPKDLVGKKYGTWNDPTELAMLKTLVE
                     SQGGDFEKVEKVPNNDSNSITPIANGVFDTAWIYYGWDGILAKSQGVDANFMYLKDYV
                     KEFDYYSPVIIANNDYLKDNKEEARKVIQAIKKGYQYAMEHPEEAADILIKNAPELKE
                     KRDFVIESQKYLSKEYASDKEKWGQFDAARWNAFYKWDKENGILKEDLTDKGFTNEFV
                     K"
     gene            12644..13372
                     /locus_tag="VU534_001486"
     CDS             12644..13372
                     /locus_tag="VU534_001486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU1514059.1"
                     /translation="MTEIRLEHVSYAYGQERILEDINLQVTSGEVVSILGPSGVGKTT
                     LFNLIAGILEVQSGRIVLDGEENPKGRVSYMLQKDLLLEHKTVLGNIILPLLIQKVDK
                     AEAISRADKILATFQLTAVRDKYPHELSGGMRQRVALLRTYLFGHKLFLLDEAFSALD
                     EMTKMELHAWYLEIHKQLQLTTLIITHSIEEALNLSDRIYILKNRPGQIVSEIKLDWS
                     EDEDKEVQKIAYKRQILAELGLDK"
     gene            13491..13949
                     /locus_tag="VU534_001487"
     CDS             13491..13949
                     /locus_tag="VU534_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HEU1514060.1"
                     /translation="MRFKNTSDHIEAYIKAILDQSGIVELQRSQLADTFQVVPSQINY
                     VIKTRFTESRGYLVESKRGGGGYIRIGRIEFSSHHEMLRELLYSIGERVSQEIYEDIL
                     QLLVEQELMTKQEMNLLESVALDRVLGEEAPVVRANMLRQIIQEVDRKGK"
     gene            13951..16383
                     /locus_tag="VU534_001488"
     CDS             13951..16383
                     /locus_tag="VU534_001488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001109706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEU1514061.1"
                     /translation="MNYSKALNECIESAYMVAGHFGARYLESWHLLIAMSNHSYSVAG
                     ATLNDYPYEMDRLEEVALELTETDYSQDETFTELPFSRRLQVLFDEAEYVASVVHAKV
                     LGTEHVLYAILHDSNALATRILERAGFSYEDKKDQVKIAALRRNLEERAGWTREDLKA
                     LRQRHRTVADKQNSMANMMGMPQTPSGGLEDYTHDLTEQARSGKLEPVIGRDKEISRM
                     IQILSRKTKNNPVLVGDAGVGKTALALGLAQRIASGDVPAEMAKMRVLELDLMNVVAG
                     TRFRGDFEERMNNIIKDIEEDGQVILFIDELHTIMGSGSGIDSTLDAANILKPALARG
                     TLRTVGATTQEEYQKHIEKDAALSRRFAKVTIEEPSVADSMTILQGLKATYEKHHRVQ
                     ITDEAVETAVKMAHRYLTSRHLPDSAIDLLDEAAATVQNKAKHVKADDSDLSPADKAL
                     MDGKWKQAAQLIAKEEEVPVYKDLVTESDILTTLSRLSGIPVQKLTQTDAKKYLNLEA
                     ELHKRVIGQDQAVSSISRAIRRNQSGIRSHKRPIGSFMFLGPTGVGKTELAKALAEVL
                     FDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYEEGGELTEKVRNKPYSVLLFDEVE
                     KAHPDIFNVLLQVLDDGVLTDSKGRKVDFSNTIIIMTSNLGATALRDDKTVGFGAKDI
                     RFDQENMEKRMFEELKKAYRPEFINRIDEKVVFHSLSSDHMQEVVKIMVKPLVASLTE
                     KGIDLKLQASALKLLANQGYDPEMGARPLRRTLQTEVEDKLAELLLKGDLVAGSTLKI
                     GVKAGQLKFDIA"
     gene            17025..17678
                     /gene="rr06"
                     /locus_tag="VU534_001489"
     CDS             17025..17678
                     /gene="rr06"
                     /locus_tag="VU534_001489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001024075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator RR06"
                     /protein_id="HEU1514062.1"
                     /translation="MNILVADDEEMIREGIAAFLTEEGYHVIMAKDGQEVLEKFQDLP
                     IHLMVLDLMMPRKSGFEVLKEINQKHDIPVIVLSALGDETTQSQVFDLYADDHVTKPF
                     SLVLLVKRIKALIRRYYVIEDLWRYQDVTVDFTSYKAHYKNEEIDLKPKELLVLKCLI
                     QHKNQVLSREQILEEISKDVADLPCDRVVDVYIRTLRKKLALDCIVTVKNVGYKISL"
     gene            17675..19006
                     /gene="hk06"
                     /locus_tag="VU534_001490"
     CDS             17675..19006
                     /gene="hk06"
                     /locus_tag="VU534_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000594665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     HK06"
                     /protein_id="HEU1514063.1"
                     /translation="MIKNPKLLTKSFLRSFAILGGVGLVIHIAIYLTFPFYYIQLEGE
                     KFNESARVFTEYLKTKTSDEIPSLLQSYSKSLTISAHLKRDIVDKRLPLVHDLDIKDG
                     KLSNYIVMLDMSVSTADGKQVTVQFVHGVDVYKEAKNILLLYLPYTFLVTIAFSFVFS
                     YFYTKRLLNPLFYISEVTSKMQDLDDNIRFDESRKDEVGEVGKQINGMYEHLLKVIYE
                     LESRNEQIVKLQNQKVSFVRGASHELKTPLASLRIILENMQHNIGDYKDHPKYIAKSI
                     NKIDQMSHLLEEVLESSKFQEWTECRETLTVKPVLVDILSRYQELAHSIGVTIENQLT
                     DATRVVMSLRALDKVLTNLISNAIKYSDKNGRVIISEQDGYLSIKNTCAPLSDQELEH
                     LFDIFYHSQIVTDKDESSGLGLYIVNNILESYQMDYSFLPYEHGMEFKISL"
     gene            19089..19616
                     /locus_tag="VU534_001491"
     CDS             19089..19616
                     /locus_tag="VU534_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenylcysteine carboxyl methyltransferase
                     family protein"
                     /protein_id="HEU1514064.1"
                     /translation="MVLAIILVTFFIRLIFLKRSIENEKRILSNGGKEFGVENTKRLT
                     MAHIVFYLSCLVEAMVHKTIFDGMGMVGLVLLIFSMLMLMLVIHLLGDIWTVKLMLVN
                     NHKYVDHILFRTVKHPNYFLNILPELIGLTLLSHAYVTFVLVFPVYAVILYRRIAEEE
                     KLLHEVIIPNGSIKR"
     gene            19695..>21439
                     /gene="cbpA"
                     /locus_tag="VU534_001492"
     CDS             19695..>21439
                     /gene="cbpA"
                     /locus_tag="VU534_001492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpA"
                     /protein_id="HEU1514065.1"
                     /translation="MFASKSERKVHYSIRKFSVGVASVVVASLVMGSVVHATENEGAT
                     QVPTSSNRANESQAEQGEQPKKLDSERDKARKEVEEYVKKIVGESYAKSTKKRHTITV
                     ALVNELNNIKNEYLNKIVESTSESQLQILMMESRSKVDEAVSKFEKDSSSSSSSDSST
                     KPEASDTAKPNKPTEPGEKVAEAKKKVEEAEKKAKDQKEEDRRNYPTITYKTLELEIA
                     ESDVEVKKAELELVKVKANEPRDEQKIKQAEAEVESKQAEATRLKKIKTDREEAEEEA
                     KRRADAKEQGKPKGRAKRGVPGELATPDKKENDAKSSDSSVGEETLPSPSLKPEKKVA
                     EAEKKVEEAKKKAEDQKEEDRRNYPTNTYKTLELEIAESDVEVKKAELELVKEEAKEP
                     RNEEKVKQAKAEVESKQAEATRLEKIKTDRKKAEEEAKRKAAEEDKVKEKPAEQPQPA
                     PAPKAEKPAPAPKPENPAEQPKAEKPADQQAEEDYARRSEEEYNRLTQQQPPKTEKPA
                     QPSTPKTGWKQENGMWYFYNTDGSMATGWLQNNGSWYYLNSNGAMATGWLQNNGSWYY
                     LNANGSMATGWLQNNG"
BASE COUNT         6776 a         3550 c         4883 g         6230 t
ORIGIN      
        1 atttgttcat atcttatttc aatccattat aaatagtgag aaatatctat cctatcttct
       61 agaatgtctt ccaaacgtgg aaactctcgt aaacaaagag gttttagagg cctatttacc
      121 atggactaaa gttgtacaag aaaagtgcaa ataagaaatc tccagattag gaactatccg
      181 tgagttctct agtctggaga tttttcaata gacttcgtta ttggacggtt acaattcata
      241 aagtgctgta gagagataac gttcaccgtt atctggtgct agggcaagga cttttttacc
      301 tgtacctaat tttttggcaa cctcgatggc tccgtagata gctgcagctg aggaaatccc
      361 tacaaggaag ccttcttttc caccaatttc acgtccgagt gcaagagcgt catctgatgt
      421 tacacgaacg ataccatcat aggctttagt atcaagtgta tcaggaataa atccagctga
      481 gataccttga attttgtgag gaccaggttt ttcaccagat agaatagcag attcatctgc
      541 ttctactgca aaaacttgaa tgttagaatt ttctgatttg agtgcatgag aaacaccaga
      601 aatcgttcca ccagtaccta ctccagcaac aaaggcatct aatccatctt taccgaaagc
      661 agctagtatc tcagctcctg ttgttctttc gtgtacttct ggattagctg gattgtcaaa
      721 ttgaagagga aggaaaccat cacgttcagc agcgatttct tgagccttag caatagcacc
      781 tttcattccc tcgctaccag gagttaggac gagttcagca ccataagctt ggataatttt
      841 acgtcgttct acactcatag tttcaggcat aacgatgacg actttatacc ctttagcagc
      901 acctacccat gaaagtccaa taccggtgtt tccacttgtt gcttcaacaa tagtagaacc
      961 aggtttcaga ataccatctt gttcagcttt ttcaatcatg ctaagggcaa tacggtcttt
     1021 tacagatgaa ccaggattaa atgcttcaag ctttatatag acgtctgcag caccttctgg
     1081 cacgatgttg ttaagtttaa caatcggtgt ttgaccgatt aattcagtaa tgttgttata
     1141 aatagacata tgaatacctc tttgtataag atatctttag tataacgcta tccataccat
     1201 ttctatatat catagatcaa agtcattaat tttcaagtga ttgcgttcag ctaattctag
     1261 taaataggtg tgaaggaaaa cgatatcagg tttcgtttga attgcttcat tttctagtat
     1321 attttggtac gcctcttttt attttgctcg ctaaagtagt tgtgagaatg tcaacgaaac
     1381 gctgtattat tcattgttta cactaagttt acaggaactt caacctctcg taaaccttgg
     1441 tcagttaaag tgacttttcc attaaaaaac tccacaagtg cagctttaat agtttctttt
     1501 tcttctttat caacataaat catcgtatcg acttgatctg taaagtttgt atccagctcc
     1561 atgagaccat gttctttaag gaagttactg tactcttggt actgagcata agacatttga
     1621 atagcaatgc cagcctgttc ttttatttca ataataccaa tttctttgac agctaaggcg
     1681 acactgccgg cgtaagcacg aattagtcct ccagcgccta gtttaatacc accaaagtag
     1741 cgtgtcacga ccacacagac attggtgaga ttgtgatttt ctagtacccc aagcatggga
     1801 acaccagcag taccactagg ctcaccatca tcacttgtac gtttaatttc actacgttct
     1861 ccaataatga aggcagagca gttatgtgtc gctttgtagt gttctttttt gatggcagta
     1921 atgaagtcac gagcctcttc ttcgctataa acacgcttgg catggcagat aaagcgagat
     1981 tttttgattt cttcttggac ttgaccgtcc tctttaattg tcctaaattc catgatttaa
     2041 ttgtactaaa aaatcatcta aagtgctagt ttttacgaat aaagaagtat gaaagtaaat
     2101 ttagattatc tcggtcgttt atttactgag aatgaattaa cagaagaaga acgtcagttg
     2161 gcggagaaac ttccagcaat gagaaaggag aaggggaaac ttttctgtca acgctgtaat
     2221 agtactattc tagaagaatg gtatttgccc atcggtgctt actattgtcg agagtgcttg
     2281 ctgatgaagc gagtcagaag tgatcaaact ttatactatt ttccgcagga ggattttcca
     2341 aagcaagatg ttctcaaatg gcgcggccaa ttaactcctt ttcaagagaa ggtgtcagag
     2401 ggattgcttc aagtagtaga caagcaaaag ccaaccttag ttcatgcggt aacaggagct
     2461 ggaaagacag aaatgattta tcaagtagtg gctaaagtga tcaatgcggg tggtgcagtg
     2521 tgtttggcta gtcctcgcat agatgtttgt ttggagctgt acaagcgcct gcaacaggat
     2581 ttttcttgcg ggatagcttt gctacatgga gaatcggaac cttattttcg aacaccacta
     2641 gttgttgcaa caacccatca gttattgaag ttttatcaag cttttgattt gctgatagtg
     2701 gatgaagtag atgcttttcc ttatgttgat aatcccatgc tttaccacgc tgtcaagaat
     2761 agtgtaaagg agaatggatt gagaatcttt ttaacagcga cttcgaccaa tgagttagat
     2821 aaaaaggtcc gtttaggaga actaaaaaga ctgaatttac cgagacggtt tcatggaaat
     2881 ccgttgatta ttccaaaacc aatttggtta tcggatttta atcgctactt agacaagaat
     2941 cgtttgtcac caaagttaaa gtcctatatt gagaagcaga gaaagacagc ttatccgtta
     3001 ctcatttttg cttcagaaat taagaaaggg gagcagttag cagaaatctt acaggagcaa
     3061 tttccaaatg agaaaattgg ctttgtatct tctgtaacag aggatcgatt agagcaagta
     3121 caagcttttc gagatggaga actgacaata cttatcagta cgacaatctt ggagcgcgga
     3181 gttaccttcc cttgtgtgga tgttttcgta gtagaggcca atcatcgttt gtttaccaag
     3241 tctagtttga ttcagattgg tggacgagtt ggacgaagca tggatagacc gacaggagat
     3301 ttgcttttct tccatgatgg gttaaatgct tcaatcaaga aggcgattaa ggaaattcag
     3361 atgatgaata aggaggctgg tctatgaagt gcttgttatg tgggcagact atgaagactg
     3421 ttttaacttt tagtagtctc ttacttctga ggaatgatga ctcttgtctt tgttcagact
     3481 gtgattctac ttttgaaaga attggggaag agaactgtcc aaattgtatg aaaacagagt
     3541 tgtcaacaaa gtgtcaagat tgtcaacttt ggtgtaaaga gggagttgaa gtcagtcata
     3601 gagcgatttt tacttacaat caagctatga aggatttttt cagtcggtat aagtttgatg
     3661 gagacttcct gttaagaaaa gttttcgctt catttttaag tgaggagttg aaaaagtaca
     3721 aagagtatca atttgttgta attcccctaa gtcctgatag atatgctaat agaggattta
     3781 atcaggttga gggcttggta gaggcagcag gctttgagta tctggattta ttagagaaaa
     3841 gagaagagag agccagttct tctaaaaatc gttcagagcg cttggggaca gaacttcctt
     3901 tctttattaa aagtggagtc actattccta aaaaaatcct acttatagat gatatctata
     3961 ctacaggagc aactataaat cgtgttaaga aactgttgga agaagctggt gctaaggatg
     4021 taaaaacatt ttcccttgta agatgaggaa aaaatttgca aaaatagaat gaaagcgtta
     4081 taataaaatc ataaaaacaa aaatgtttag aaagaaggta ctcatatgat taaatatagt
     4141 atccgtggtg aaaacctaga agtaacagaa gcaattcgtg attatgtagt ttctaaactc
     4201 gaaaagatcg aaaagtactt ccaaccagaa caagagttgg atgcccgaat taacttaaaa
     4261 gtttatcgtg aaaaaacggc taaagtggaa gtaacgattc cgcttggatc tattactctc
     4321 cgcgcagaag atgtatctca agatatgtat ggttcaattg accttgtaac tgataaaatt
     4381 gaacgtcaga ttcgtaaaaa taaaacaaaa atcgagcgta aaaataaaaa taaggtagca
     4441 actggtcaat tatttacaga tgctttggtg gaagattcaa atattgtcca gtctaaagtt
     4501 gttcgttcaa aacaaattga tttaaaacca atggatttgg aagaagcaat tctacaaatg
     4561 gatttattgg ggcatgattt ctttatctat gtggatgttg aagatcagac aaccaatgtg
     4621 atttatcgtc gtgaggatgg cgaaattggt ttgttagagg ttaaagaatc ttaatttcaa
     4681 tatgtgtaaa ggtaggttta ctgaattgta aactaccttt ttcttataat tgatagaatt
     4741 actgattaca cttttaaaaa gtcgcttttt gaggggtatt atggtataat gggtgccaag
     4801 aggttttgaa tgaaaaaatt ttatgtaagt ccaatttttc ctattctagt aggattgatt
     4861 gcgtttggag tcttatccac tttcattatt tttgttaata ataatctgtt gacggtttta
     4921 attttgtttc tttttgtagg aggctatgtt tttttattta agaaactgag agtgcattat
     4981 acaaggagtg atgtagaaca gatacagtat gtaaaccacc aagcggaaga aagtttgaca
     5041 gctctattgg aacagatgcc tgtaggtgtt atgaaattga atttatcttc tggagaggtt
     5101 gagtggttta atccctatgc tgaattgatt ttgaccaagg aagatggtga ttttgattta
     5161 gaagctgttc aaacgattat caaggcttca gtaggaaatc cgtctactta tgccaagctt
     5221 ggtgagaagc gttatgctgt tcatatggat gcttcttccg gtgttttgta ttttgtagat
     5281 gtatccaggg aacaagccat aacagatgaa ttggtaacaa gtagaccagt gattgggatt
     5341 gtctctgtgg ataattatga tgatttggag gatgaaactt ctgagtcaga tattagtcaa
     5401 atcaatagtt ttgtagctaa ttttatatca gagttttcag aaaaacacat gatgttttct
     5461 cgtcgggtaa gtatggatcg attttatcta tttactgact acacggtgct tgagggcttg
     5521 atgaatgata aattttctgt tattgatgct ttcagagaag agtcgaaaca gagacagttg
     5581 cccttgacct taagtatggg attttcttat ggcgatggaa atcatgatga gatagggaaa
     5641 gttgctttgc tcaatttgaa cttggctgaa gtacgtggtg gcgaccaggt ggttgttaag
     5701 gaaaacgacg aaacgaaaaa tccagtttat tttggtggtg ggtctgctgc ttcaatcaag
     5761 cgtacacgga ctcgtacgcg cgctatgatg acagctattt cagataagat tcggagtgta
     5821 gatcaggttt ttgtagtcgg tcacaaaaat ttagacatgg atgctttggg ctctgctgta
     5881 ggtatgcagt tgttcgccag aaatgtgatt gaaaatagct atgctcttta tgatgaagaa
     5941 caaatgtctc cagatattga acgagctgtt tcattcatag aaaaagaagg agttacgaag
     6001 ttgttgtctg ttaaggatgc aatggggatg gtgaccaatc gttctttgtt gattcttgta
     6061 gaccattcaa agacagcctt aacattatca aaagaatttt atgatttatt tacccaaacc
     6121 attgttattg accaccatag aagggatcag gattttccag ataatgcggt tattacttat
     6181 atcgaaagtg gtgcaagtag tgccagtgag ttggtaacgg aattgattca gttccagaat
     6241 tctaagaaaa atcgtttgag tcgtatgcaa gcaagtgtct tgatggctgg tatgatgttg
     6301 gatactaaaa atttcacctc gcgagtaact agtcggacat ttgatgttgc tagctatctc
     6361 agaacgcgcg gaagtgatag tattgctatc caggaaatcg ctgcgacaga ttttgaagaa
     6421 tatcgtgagg tcaatgaact tattttacag gggcgtaaat taggttcaga tgtactaata
     6481 gcagaggcta aggacatgaa atgctatgat acagttgtta ttagtaaggc agcagatgcc
     6541 atgttagcca tgtcaggtat tgaagcgagt tttgttcttg cgaagaatac acaaggattt
     6601 atctctatct cagctcgaag tcgtagtaaa ctgaatgtac aacggattat ggaagagtta
     6661 ggcggtggag gccactttaa tttggcagca gctcaaatta aagatgtaac cttgtcagaa
     6721 gcaggtgaaa aactgacaga aattgtatta aatgaaatga aggaaaagga gaaagaagaa
     6781 tgaaagtaat ctttttagca gatgttaaag gaaaaggtaa aaaaggcgaa attaaggaag
     6841 taccaacagg gtatgcgcaa aactttctta tcaaaaagaa tctagccaaa gaagcgactg
     6901 ctcaagctgt aggtgaactt cgtggtaaac aaaaatcgga agaaaaagct cacgctgaga
     6961 tgattgcaga aggaaaagca attaaagcac aacttgaagc agaagaaact gttgtagaat
     7021 ttgttgaaaa agttggtcca gatggtcgta cctttggttc tattaccaat aagaagattg
     7081 cagaagaatt gcaaaagcaa tttggaatta agattgataa acgtcatatt caagtacaag
     7141 ctccgattcg agcggttggt ttgattgatg tgccagtgaa aatctatcaa gatatcacaa
     7201 gtgtaatcaa tcttcgtgtg aaagaaggat aagtttacac cttcttgaca agattgtaaa
     7261 aggaagggaa gtctgatggc agaagtagaa gagttacgag tacaacctca agatatctta
     7321 gctgagcaat ccgttttagg ggctatcttt attgatgaga gtaaacttgt ttttgtgcga
     7381 gaatacattg agtctcggga cttttttaag tatgcccatc gtttgatttt ccaagccatg
     7441 gtcgatttat ccgatcgtgg tgatgccata gatgcaacaa cggttcgtac tatccttgat
     7501 aatcaaggtg atttacagaa tattggtggc ttgtcttact tggttgagat tgttaattct
     7561 gtgccaactt ctgctaatgc ggagtattat gctaagattg ttgcagaaaa agcaatgcta
     7621 cgtcgtttaa ttgccaagtt gacagagtct gtcaaccaag cttacgaagc gtcacaacca
     7681 gctgatgaaa ttattgctca ggcagaaaaa gggttgattg atgtcagtga aaatgcaaat
     7741 cgaagcgggt ttaagaacat tcgagatgtg ttgaatctca actttggaaa tctggaagct
     7801 cgctcgcaac aaacgaccga tattacaggt attgcgacag gttatcgtga tttggatcat
     7861 atgacaacag gacttcatga ggaggagttg attatcttag cagctcgtcc agcagttggt
     7921 aagacagcat ttgccttgaa tatcgctcag aacattggga ctaagttgga caaaacggtt
     7981 gctatttttt cactcgaaat gggtgcggaa agcttggtag atcgtatgtt agctgcagaa
     8041 ggcttagtgg agtcacattc tatccgtaca gggcaattga cagatgagga gtggcaaaaa
     8101 tatactattg ctcagggtaa tctagctaac gccagtatct atatcgatga tacgccaggt
     8161 attcggatta cagagattcg ttctcgttct cgtaaattgg ctcaagaaac tggaaatctt
     8221 ggtttgattt tgatagacta tttgcaactt atcacgggaa ctggtcgaga aaatcgtcaa
     8281 caagaagttt ctgaaatttc tcgtcagttg aaaatactag ccaaggaatt gaaggttcca
     8341 gtaatcgctc tgagtcagct ttctcgtggt gtagaacaac gtcaggacaa gagaccggtc
     8401 ttgtctgata ttcgtgaatc tgggtctatt gagcaggacg ctgatatcgt agcttttctc
     8461 tatcgcgatg actactatga acgtggtggt gaagaagagg agggtatccc aaataataag
     8521 gtggaagtta ttatcgagaa aaaccgtagt ggagctcgtg gaacagtgga attgattttc
     8581 caaaaagaat acaataaatt ttcaagtatc tcaaagaggg aggcataaga tgtcagatgc
     8641 atttacagat gtagccaaga tgaaaaaaat caaagaagaa atcaaggcac atgagggaca
     8701 agtcgtagaa atgactttgg agaatggtcg taagcgccaa aaaaatagat tgggtaagct
     8761 aattgaagtt tatccatctc tatttattgt ggagtttggg gatgtggaag gagataaaca
     8821 agttaatgtt tacgttgaat cctttactta ctcagatatt cttacagaaa agaatttgat
     8881 tcattatctt gactaaagtg agaaattttc tcactttttc ttttttctcc gaataattta
     8941 ggtgaaggca atcatcgctt tatattattt ttcaaggagg aagaatgaaa attttaccgt
     9001 ttatagcaag aggaacaagt tattacttga agatgtcagt taaaaagctt gttccttttt
     9061 tagtagtagg attgatgcta gcagctggtg atagtgtcta tgcctattcc agaggaaatg
     9121 gatcgattgc gcgtggggat gattatcctg cttattataa aaatgggagc caggagattg
     9181 atcagtggcg catgtattct cgtcagtgta cttcttttgt agcctttcgt ttgagtaatg
     9241 tcaatggttt tgaaattccg gcagcttatg gaaatgcgaa tgaatgggga catcgtgctc
     9301 gtcgggaagg ttatcgtgta gataatacac cgacgattgg ttccattact tggtctactg
     9361 caggaactta tggtcatgtt gcctgggtgt caaatgtaat gggagatcag attgagattg
     9421 aggaatataa ctatggttat acagaatcct ataataaacg agttataaaa gcaaacacga
     9481 tgacaggatt tattcatttt aaagatttgg atggtggcag tgttgggaat agtcaatcct
     9541 caacttcaac aggcggaact cattatttta agaccaagtc tgctattaaa actgaacctc
     9601 tagctagcgg aactgtgatt gattactatt atcctgggga gaaggttcat tatgatcaga
     9661 tacttgaaaa agacggctat aagtggttga gttatactgc ctataatgga agctatcgtt
     9721 atgttcaatt ggaggctgtg aataaaaatc ctctaggtaa ttctgttctt tcttcaacag
     9781 gtggaactca ttattttaag accaagtctg ctatcaaaac tgaaccccta gttagtgcaa
     9841 ctgtgattga ttactattat cctggagaga aggttcatta tgatcaaatt ctcgaaaaag
     9901 acggctacaa gtggttgagt tatacggctt ataacggaag tcgtcgctat atacagctag
     9961 agggagtgac ttcttcacaa aattatcaga atcaatcagg aaacatctct agctatggat
    10021 cccatagtag ttcaactgtc ggttggaaga aaataaatgg tagttggtat catttcaaat
    10081 caaatggttc taaatcaaca ggatggctga aagacggttc tagctggtat tatttgaaat
    10141 tatctggtga aatgcagaca ggatggttaa aggaaaatgg tttgtggtat tatctgggta
    10201 gttcaggggc aatgaaaaca ggctggtacc aggtctctgg taagtggtat tattcttact
    10261 cttcaggcgc cttagctgtt aatacgacgg tggatggcta cagagtaaac agtgatggag
    10321 aacgagtata gaaaattgga gtaggagaaa tttcctgctc ttttctgtaa gcagtttcct
    10381 tgacattttt cttattttgc gctatcatat atacatataa tatatgggag tctgtgtaca
    10441 gtctgagagg aagtgttaaa cttcgaccgc acctgatctg ggtaatgcca gcggagggaa
    10501 cgatacttag tctaattttg caccttttcc atgtatggta aaggtttttc tttttttaaa
    10561 aaggaaaacg agaagaggag gttcttatga aagcaagcat tgccttgcaa gttttacccc
    10621 tagtacaggg gattgatcgg atagctgtta ttgatcaggt cattgcttat ctgcaaactc
    10681 aagaagtgac gatggtagtg acaccatttg aaacggtctt ggaaggggag tttgatgagc
    10741 ttatgcgcat tctaaaagaa gcgctggaag tggcagggca ggaggcagac aatgtctttg
    10801 ccaatgtcaa aataaatgta ggagagattt taagtattga tgagaaactt gagaagtata
    10861 ctgagacgac acattagtct attgggcttt ctcggagtat tgtcaatctg gcagttagca
    10921 ggttttctta aacttctccc caagtttatc ctgccgacac ctcttgaaat tctccagccc
    10981 tttgttcgtg acagagaatt tctctggcac catagctggg cgaccttgag agtggcttta
    11041 ctggggctga ttttgggagt tttgattgcc tgtcttatgg ctgtgctcat ggatagtttg
    11101 acttggctca atgacctgat ttaccctatg atggtggtca ttcagaccat tccgaccatt
    11161 gccatagctc ctatcctggt cttgtggcta ggttatggga ttttgcccaa gattgtcttg
    11221 attatcttaa cgacaacctt tcccatcatc gttagtattt tggacggttt taggcattgc
    11281 gacaaggata tgctgacctt gtttagtctg atgcgggcca agccttggca aatcctgtgg
    11341 cattttaaaa tcccagttag cctgccttac ttttatgcag gtctgagggt cagtgtctcc
    11401 tacgccttta tcacaactgt ggtatctgag tggttgggag gttttgaagg tcttggtgtt
    11461 tatatgattc agtctaaaaa actgtttcag tatgatacca tgtttgccat tattattctg
    11521 gtgtcgatta tcagtctttt gggtatgaag ctggtcgata tcagtgaaaa atatgtgatt
    11581 aaatggaaac gttcgtagaa ttagaatgtt tctgaaaaag aaaagaggaa atcaaaatga
    11641 agaaaacatg gaaagtgttt ttaacgcttg taacagctct tgtagctgtt gtgcttgtgg
    11701 cctgtggtca aggaactgct tctaaagaca acaaagaggc agaacttaag aaggttgact
    11761 ttatcctaga ctggacacca aataccaacc acacagggct ttatgttgcc aaggaaaaag
    11821 gttatttcaa agaagctgga gtggatgttg atttgaaatt gccaccagaa gaaagttctt
    11881 ctgacttggt tatcaacgga aaggcaccat ttgcagtgta tttccaagac tacatggcta
    11941 agaaattgga aaaaggagca ggaatcactg ccgttgcagc tattgttgaa cacaatacat
    12001 caggaatcat ctctcgtaaa tctgataatg taagcagtcc aaaagacttg gttggtaaga
    12061 aatatgggac atggaatgac ccaactgaac ttgctatgtt gaaaaccttg gtagaatctc
    12121 aaggtggaga ctttgagaag gttgaaaaag taccaaataa cgactcaaac tcaatcacac
    12181 cgattgccaa tggcgtcttt gatactgctt ggatttacta cggttgggat ggtatccttg
    12241 ctaaatctca aggtgtagat gctaacttca tgtacttgaa agactatgtc aaggagtttg
    12301 actactattc accagttatc atcgcaaaca acgactatct gaaagataac aaagaagaag
    12361 ctcgcaaagt catccaagcc atcaaaaaag gctaccaata tgccatggaa catccagaag
    12421 aagctgcaga tattctcatc aagaatgcac ctgaactcaa ggaaaaacgt gactttgtca
    12481 tcgaatctca aaaatacttg tcaaaagaat acgcaagcga caaggaaaaa tggggtcaat
    12541 ttgacgcagc tcgctggaat gctttctaca aatgggataa agaaaatggt atccttaaag
    12601 aagacttgac agacaaaggc ttcaccaacg aatttgtgaa ataatgacag aaattagact
    12661 agagcacgtc agttatgcct atggtcagga gaggatttta gaggatatca acctacaggt
    12721 gacttcaggc gaagtggttt ccatcctagg cccaagtggt gttggaaaga ccaccctctt
    12781 taatctaatc gctgggattt tagaagttca gtcagggaga attgtccttg atggtgaaga
    12841 aaatcccaag gggcgcgtga gttatatgtt gcaaaaggat ctgctcttgg agcacaagac
    12901 ggtgcttgga aatatcattc tgcccctctt gattcaaaag gtggataagg cagaagctat
    12961 ttcccgagcg gataaaattc ttgcgacctt ccagctgaca gctgtaagag acaagtatcc
    13021 tcatgaactt agcggtggga tgcgccagcg tgtagcctta ctccggacct acctttttgg
    13081 gcacaagctc tttctcttag atgaggcctt tagcgccttg gatgagatga caaagatgga
    13141 actccacgct tggtatcttg agattcacaa gcagttgcag ctaacaaccc tgatcatcac
    13201 gcatagtatt gaggaggccc tcaatctcag cgaccgtatc tatatcttga aaaatcgccc
    13261 tgggcagatt gtttcagaaa ttaaactaga ttggtctgaa gatgaggaca aggaagtcca
    13321 aaagattgcc tacaaacgtc aaattttggc ggaattaggc ttagataagt agaaaaatag
    13381 ggagttggtg aagattatcc tttaccagcg ccctttttct tttaaaaatg agaaaatttc
    13441 ggtataatag tcaaacaagg tcaaggttta aagagagagg tgggtttgtt atgagattta
    13501 aaaatacatc ggatcatatt gaggcctaca tcaaggcgat tttagatcaa tctggtatcg
    13561 tggagttgca acggagtcag ttggcagata cctttcaggt tgttcctagt cagattaact
    13621 acgtgatcaa gacacgcttt acggaaagta gaggctactt ggttgaaagt aagcgtggtg
    13681 gcggaggcta cattcgtata ggacggattg agttttctag tcatcatgaa atgctccggg
    13741 agctgcttta ctcgattggt gagcgagtca gtcaagaaat ttatgaggat attctccagc
    13801 ttttggttga gcaggaattg atgaccaagc aggagatgaa tttgctagaa tcagtagctt
    13861 tggatcgcgt tttaggagaa gaagctccag ttgttcgagc aaacatgcta cgtcagatca
    13921 tacaagaggt agatagaaaa gggaagtaag atgaactatt caaaagcatt gaatgaatgt
    13981 atcgaaagtg cctacatggt tgctggacat tttggagctc gttatctaga gtcgtggcac
    14041 ttgttgattg ccatgtctaa tcacagttat agtgtagcag gggcaacttt aaatgattat
    14101 ccgtatgaga tggaccgttt agaagaggtg gctttggaac tgactgaaac ggactatagc
    14161 caggatgaaa cctttacgga attgccgttc tcccgtcgtt tgcaggttct ttttgatgaa
    14221 gcagagtatg tagcgtcagt ggtccatgct aaggtactag ggacagagca cgtcctctat
    14281 gcgattttgc atgatagcaa tgccttggcg actcgtatct tggagagggc tggtttttct
    14341 tatgaagaca agaaagatca ggtcaagatt gctgctcttc gtcgaaattt agaagaacgg
    14401 gcaggctgga ctcgtgaaga tctcaaggct ttacgccaac gccatcgtac agtagctgac
    14461 aagcaaaatt ctatggccaa tatgatgggc atgccgcaga ctcctagtgg tggtctcgag
    14521 gattatacgc atgatttgac agagcaagcg cgttctggca agttagaacc agtcatcggt
    14581 cgggacaagg aaatctcacg tatgattcaa atcttgagcc ggaagactaa gaacaaccct
    14641 gtcttggttg gggatgctgg tgtcgggaaa acagctctgg cgcttggtct tgcccagcgt
    14701 attgctagtg gtgacgtgcc tgcggaaatg gctaagatgc gcgtgttaga acttgatttg
    14761 atgaatgtcg ttgcagggac acgcttccgt ggtgactttg aagaacgcat gaataatatc
    14821 atcaaggata ttgaagaaga tggccaagtc atcctcttta tcgatgaact ccacaccatc
    14881 atgggttctg gtagcgggat tgattcgact ctggatgcgg ccaatatctt gaaaccagcc
    14941 ttggcgcgtg gaactttgag aacggttggt gccactactc aggaagaata tcaaaaacat
    15001 atcgaaaaag atgcggcact ttctcgtcgt ttcgctaaag tgacgattga agaaccaagt
    15061 gtggcagata gtatgactat tttacaaggt ttgaaggcga cttatgagaa acatcaccgt
    15121 gtacaaatca cagatgaagc ggttgaaaca gcggttaaga tggctcatcg ttatttaacc
    15181 agtcgtcact tgccagactc tgctatcgat ctcttggatg aggcggcagc aacagtgcaa
    15241 aataaggcaa agcatgtaaa agcagacgat tcagatttga gtccagctga caaggccctg
    15301 atggatggca agtggaaaca ggcagcccag ctaatcgcaa aagaagagga agtacctgtc
    15361 tacaaagact tggtgacaga gtctgatatt ttgaccacct tgagtcgctt gtcaggaatc
    15421 ccagttcaaa aactgactca aacggatgct aagaagtatt taaatcttga agcagaactc
    15481 cataaacggg ttatcggtca agatcaagct gtttcaagca ttagccgtgc cattcgccgc
    15541 aaccagtcag ggattcgcag tcataagcgt ccgattggtt cctttatgtt cctagggcct
    15601 acaggtgtcg ggaaaactga attagccaag gctctggcag aagttctttt tgacgacgaa
    15661 tcagccctta tccgctttga tatgagtgag tatatggaga aatttgcagc tagtcgtctc
    15721 aacggagctc ctccaggcta tgtaggatat gaagaaggtg gggagttgac agagaaggtt
    15781 cgcaataaac cctattccgt tctcctcttt gatgaggtag agaaggccca cccagatatc
    15841 tttaatgttc tcttgcaggt tctggatgac ggtgtcttga cagatagcaa gggacgcaag
    15901 gtcgattttt caaataccat tatcattatg acatcgaatc taggtgcgac tgcccttcgt
    15961 gatgataaga ctgttggttt tggggctaag gatattcgtt ttgaccagga aaatatggaa
    16021 aaacgcatgt ttgaagaact gaaaaaagct tatagaccgg aattcatcaa ccgtattgat
    16081 gagaaggtgg tcttccatag cctatctagt gatcatatgc aggaagtggt gaagattatg
    16141 gtcaagcctt tagtggcaag tttgactgaa aaaggcattg acttgaaatt acaagcttca
    16201 gctctgaaat tgttagcaaa tcaaggatat gacccagaga tgggagctcg cccacttcgc
    16261 agaaccctgc aaacagaagt ggaggacaag ttggcagaac ttcttctcaa gggagattta
    16321 gtggcaggca gcacacttaa gattggtgtc aaagcaggcc agttaaaatt tgatattgca
    16381 taaaagaata aaagtatcag catctgacca taagtcacag tggagtgaaa ttcaatgaaa
    16441 atcaaagagc aaactaggca gctagccgca ggttgctcaa aacactggtt tgaggttgca
    16501 gatagagctg acgtggtttg aagagatttt cgaagagtat gaaactaaaa cctatagctt
    16561 ctaaacgatc cgtggttttc atcattcaac acaaaattca tatgtttatt accctccgtc
    16621 gtatttgtct tagagcgtgt gtagtagaaa aagagcagtc ttatctgaaa tttttattct
    16681 ttcaaaagag acctgtttct tttttgcatg tcaaatccgt tctagctggt atttgaaaaa
    16741 tcaaactaat attcaatgaa aatcaaagaa caaactagga agctagccgc aggttgctca
    16801 aaacactgtt ttgaggttgt agatagagct gacgtggttt gaagagattt tcgaagagta
    16861 taagctgcaa gatgaatgat tttcttgtat tgacgttgtt gttgacaaaa agtagcggat
    16921 aaatgaaatc cattccatta tcatagatga taggctggta ggaaattttc aaatagcata
    16981 caggaaatag atgtatggag ttctggtagt agaaagggag agagatgaac attttagttg
    17041 cagatgacga ggaaatgatt agagaaggaa ttgcagcatt tctgacagaa gagggttatc
    17101 atgtcattat ggctaaggat ggacaagagg tcttggaaaa atttcaagat ctccctatcc
    17161 atctcatggt actggattta atgatgccta ggaagagtgg ttttgaagtg ttaaaagaaa
    17221 tcaatcaaaa gcacgatatt cctgtcatcg tcttgagtgc tctgggagat gaaactactc
    17281 agtcacaggt atttgatctc tatgctgatg atcatgtgac aaaacctttt tctttggtac
    17341 tgcttgtcaa gcgtattaag gcgcttatca gacgttacta cgtcatagag gatctttggc
    17401 gatatcagga tgtaacagtg gattttacct cttacaaagc acattataaa aatgaagaaa
    17461 ttgatctcaa accaaaggaa ttactggtac taaagtgttt gattcagcat aaaaatcaag
    17521 ttttaagtag agagcagata ttggaagaaa tttcaaaaga tgtagctgat ttaccttgtg
    17581 atagggtcgt tgatgtctat attcgtactc ttcgcaaaaa attagcttta gattgtatcg
    17641 tgactgtgaa aaatgttggg tataagatta gcttatgata aaaaatccta aattattaac
    17701 caagtctttt ttaagaagtt ttgcaattct aggtggtgtt ggtctagtca ttcatatagc
    17761 tatttatttg acctttcctt tttattatat tcaactggag ggggaaaagt ttaatgagag
    17821 cgcaagagtg tttacggagt atttaaagac taagacatct gatgaaattc caagcttact
    17881 ccagtcttat tcaaagtcct tgaccatatc tgctcacctt aaaagagata ttgtagataa
    17941 gcggctccct cttgtgcatg acttggatat taaagatgga aagctatcaa attatatcgt
    18001 gatgttagat atgtctgtta gtacagcaga tggtaaacag gtaaccgtgc aatttgttca
    18061 cggggtggat gtctacaaag aagcaaagaa tattttgctt ttgtatctcc catatacatt
    18121 tttggttaca attgcttttt cctttgtttt ttcttatttt tatactaaac gcttgctcaa
    18181 tcctcttttt tacatttcag aagtgactag taaaatgcaa gatttggatg acaatattcg
    18241 ttttgatgaa agtaggaaag atgaagttgg tgaagttgga aaacagatta atggtatgta
    18301 tgagcacttg ttgaaggtta tttatgagtt ggaaagtcgt aatgagcaaa ttgtaaaatt
    18361 gcaaaatcaa aaggtttcct ttgtccgcgg agcatcacat gagttgaaaa cccctttagc
    18421 cagtcttaga attatcctag agaatatgca gcataatatt ggagattaca aagatcatcc
    18481 aaaatatatt gcaaagagta taaataagat tgaccagatg agccacttat tagaagaagt
    18541 actggagtct tctaaattcc aagagtggac agagtgtcgt gagaccttga ctgttaagcc
    18601 agttttagta gatattttat cacgttatca agaattagct cattcaatag gtgttacaat
    18661 tgaaaatcaa ttgacagatg ctaccagggt cgtcatgagt cttagggcat tggataaggt
    18721 tttgacaaac ctgattagta atgcaattaa atattcagat aaaaatgggc gtgtaatcat
    18781 atccgagcaa gatggctatc tctctatcaa aaatacatgt gcgcctctaa gtgaccaaga
    18841 actagaacat ttatttgata tattctatca ttctcaaatc gtgacagata aggatgaaag
    18901 ttccggtttg ggtctttaca ttgtgaataa tattttagaa agctatcaaa tggattatag
    18961 ttttctccct tatgaacacg gtatggaatt taagattagc ttgtagacag attagttttt
    19021 tattaaagtt catatagggt taacataagt gtgttattct ttgtgtagat aaaagaaagg
    19081 atactaatat ggtattagcg attattttag taacattctt tattcgattg atttttttaa
    19141 agcgttcgat agagaatgag aaacgaatcc ttagcaatgg cgggaaagaa tttggagttg
    19201 agaatacaaa acgattaact atggctcata ttgtttttta tctctcttgc ttggttgagg
    19261 caatggtgca caagacaatt tttgatggca tgggcatggt tggtttagtc ttgcttattt
    19321 tttctatgct gatgttgatg ttggtgattc acttgttggg agatatttgg acagtgaagc
    19381 ttatgcttgt caataatcac aaatatgtag atcatatctt gtttaggaca gtaaaacacc
    19441 ctaattactt tttaaatatt cttcctgagt tgattggctt gaccttgttg agtcatgctt
    19501 atgtgacttt tgttttagtt tttccagttt atgcagttat tttgtatcga cgaatagctg
    19561 aagaggaaaa gctattacat gaagttataa tcccaaatgg aagcataaag agataaatac
    19621 aaaattcgat ttatatacag ttcatattga agtgatatag taaggttaaa gaaaaaatat
    19681 agaaggaaat aaacatgttt gcatcaaaaa gcgaaagaaa agtacattat tcaattcgta
    19741 aatttagtgt tggagtagct agtgtagttg ttgccagtct tgttatggga agtgtggttc
    19801 atgcgacaga gaacgaggga gctacccaag tacccacttc ttctaatagg gcaaatgaaa
    19861 gtcaggcaga acaaggagaa caacctaaaa aactcgattc agaacgagat aaggcaagga
    19921 aagaggtcga ggaatatgta aaaaaaatag tgggtgagag ctatgcaaaa tcaactaaaa
    19981 agcgacatac aattactgta gctctagtta acgagttgaa caacattaag aacgagtatt
    20041 tgaataaaat agttgaatca acctcagaaa gccaactaca gatactgatg atggagagtc
    20101 gatcaaaagt agatgaagct gtgtctaagt ttgaaaagga ctcatcttct tcgtcaagtt
    20161 cagactcttc cactaaaccg gaagcttcag atacagcgaa gccaaacaag ccgacagaac
    20221 caggagaaaa ggtagcagaa gctaagaaga aggttgaaga agctgagaaa aaagccaagg
    20281 atcaaaaaga agaagatcgt cgtaactacc caaccattac ttacaaaacg cttgaacttg
    20341 aaattgctga gtccgatgtg gaagttaaaa aagcggagct tgaactagta aaagtgaaag
    20401 ctaacgaacc tcgagacgag caaaaaatta agcaagcaga agcggaagtt gagagtaaac
    20461 aagctgaggc tacaaggtta aaaaaaatca agacagatcg tgaagaagca gaagaagaag
    20521 ctaaacgaag agcagatgct aaagagcaag gtaaaccaaa ggggcgggca aaacgaggag
    20581 ttcctggaga gctagcaaca cctgataaaa aagaaaatga tgcgaagtct tcagattcta
    20641 gcgtaggtga agaaactctt ccaagcccat ccctgaaacc agaaaaaaag gtagcagaag
    20701 ctgagaagaa ggttgaagaa gctaagaaaa aagccgagga tcaaaaagaa gaagatcgcc
    20761 gtaactaccc aaccaatact tacaaaacgc ttgaacttga aattgctgag tccgatgtgg
    20821 aagttaaaaa agcggagctt gaactagtaa aagaggaagc taaggaacct cgaaacgagg
    20881 aaaaagttaa gcaagcaaaa gcggaagttg agagtaaaca agctgaggct acaaggttag
    20941 aaaaaatcaa gacagatcgt aaaaaagcag aagaagaagc taaacgaaaa gcagcagaag
    21001 aagataaagt taaagaaaaa ccagctgaac aaccacaacc agcgccggct ccaaaagcag
    21061 aaaaaccagc tccagctcca aaaccagaga atccagctga acaaccaaaa gcagaaaaac
    21121 cagctgatca acaagctgaa gaagactatg ctcgtagatc agaagaagaa tataatcgct
    21181 tgactcaaca gcaaccgcca aaaactgaaa aaccagcaca accatctact ccaaaaacag
    21241 gctggaaaca agaaaacggt atgtggtact tctacaatac tgatggttca atggcgacag
    21301 gatggctcca aaacaatggc tcatggtact acctcaacag caatggcgct atggcgacag
    21361 gatggctcca aaacaatggt tcatggtact atctaaacgc taatggttca atggcaacag
    21421 gatggctcca aaacaatgg
//
LOCUS       DAVFER010000037        20651 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1105170250
            SAMEA2167659-rid19724873.denovo.037, whole genome shotgun sequence.
ACCESSION   DAVFER010000037 DAVFER010000000
VERSION     DAVFER010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2167659
            Sequence Read Archive: ERR388902
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20651)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20651)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928716.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928716.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 04:07:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,118
            CDSs (total)                      :: 2,073
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 120
            CDSs (without protein)            :: 120
            Pseudo Genes (ambiguous residues) :: 0 of 120
            Pseudo Genes (frameshifted)       :: 67 of 120
            Pseudo Genes (incomplete)         :: 47 of 120
            Pseudo Genes (internal stop)      :: 34 of 120
            Pseudo Genes (multiple problems)  :: 23 of 120
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20651
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2167659-rid19724873.denovo.037"
                     /strain="1105170250"
                     /db_xref="taxon:1313"
     gene            complement(471..2198)
                     /gene="ezrA"
                     /locus_tag="VU534_001493"
     CDS             complement(471..2198)
                     /gene="ezrA"
                     /locus_tag="VU534_001493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000064817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HEU1514066.1"
                     /translation="MSNGQLIYLMVAIAVILVLAYVVAIFLRKRNEGRLEALEEKKEE
                     LYNLPVNDEVEAVKNMHLIGQSQVAFREWNQKWVDLSLNSFADIENNLFEAEGYNHSF
                     RFLKASHQIDQIESQITLIEEDIAAIRNALADLEKQESKNSGRVLHALDLFEELQHRV
                     AENSEQYGQALDEIEKQLENIQSEFSQFVTLNSSGDPVEAAVILDNTENHILALSHIV
                     DRVPALVTTLSTELPDQLQDLEAGYRKLIDANYHFVETDIEARFHLLYEAFKKNQENI
                     RQLELDNAEYENGQAQEEINALYDIFTREIAAQKVVENLLATLPTYLQHMKENNTLLG
                     EDIARLNKTYLLPETAASHVRRIQTELESFEAAIVEVTSNQEEPTQAYSVLEENLEDL
                     QTQLKDIEDEQISVSERLTQIEKDDINARQKANVYVNRLHTIKRYMEKRNLPGIPQTF
                     LKLFFTASNNTEDLMVELEQKMINIESVTRVLEIATNDMEALETETYNIVQYATLTEQ
                     LLQYSNRYRSFDERIQEAFNEALDIFEKEFDYHASFDKISQALEVAEPGVTNRFVTSY
                     EKTRETIRF"
     gene            complement(2280..4226)
                     /gene="gyrB"
                     /locus_tag="VU534_001494"
     CDS             complement(2280..4226)
                     /gene="gyrB"
                     /locus_tag="VU534_001494"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002283665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HEU1514067.1"
                     /translation="MTEEIKNLQAQDYDASQIQVLEGLEAVRMRPGMYIGSTSKEGLH
                     HLVWEIVDNSIDEALAGFASHIQVFIEPDDSITVVDDGRGIPVDIQEKTGRPAVETVF
                     TVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVHVHKNGKIHYQEYRRGHVVAD
                     LEIVGDTDKTGTTVHFTPDPKIFTETTIFDFDKLNKRIQELAFLNRGLQISITDKRQG
                     LEQTKHYHYEGGIASYVEYINENKDVIFDTPIYTDGEMDDITVEVAMQYTTGYHENVM
                     SFANNIHTHEGGTHEQGFRTALTRVINDYARKNKLLKDNEDNLTGEDVREGLTAVISV
                     KHPNPQFEGQTKTKLGNSEVVKITNRLFSEAFSDFLMENPQIAKRIVEKGILAAKARV
                     AAKRAREVTRKKSGLEISNLPGKLADCSSNNPAETELFIVEGDSAGGSAKSGRNREFQ
                     AILPIRGKILNVEKASMDKILANEEIRSLFTAMGTGFGAEFDVSKARYQKLVLMTDAD
                     VDGAHIRTLLLTLIYRYMKPILEAGYVYIAQPPIYGVKVGSEIKEYIQPGADQEIKLQ
                     EALARYSEGRTKPTIQRYKGLGEMDDHQLWETTMDPEHRLMARVSVDDAAEADKIFDM
                     LMGDRVEPRREFIEENAVYSTLDV"
     gene            complement(4241..4804)
                     /locus_tag="VU534_001495"
     CDS             complement(4241..4804)
                     /locus_tag="VU534_001495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEU1514068.1"
                     /translation="MKYHDYIWDLGGTLLDNYETSTAAFVETLALYGITQDHDSVYQA
                     LKVSTPFAIETFAPNLENFLEKYKENEARELEHPILFEGVSDLLEDISNQGGRHFLVS
                     HRNDQVLEILEKTSIAAYFTEVVTSSSGFKRKPNPESMLYLREKYQISSGLVIGDRPI
                     DIEAGQAAGLDTHLFTSIVNLRQVLDI"
     gene            complement(4889..5443)
                     /locus_tag="VU534_001496"
     CDS             complement(4889..5443)
                     /locus_tag="VU534_001496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DJ-1/PfpI family protein"
                     /protein_id="HEU1514069.1"
                     /translation="MVKVAVILAQGFEEIEALTVVDVLRRANITCDMVGFEEQVTGSH
                     AIQVRADHVFDGDLSDYDMIVLPGGMPGSAHLRDNQTLIQELQSFEQEGKKLAAICAA
                     PIALNQAEILKNKRYTCYDGVQEQILDGHYVKETVVVDGQLTTSRGPSTALAFAYELV
                     EQLGGDAESLRTGMLYRDVFGKNQ"
     gene            complement(5454..6677)
                     /locus_tag="VU534_001497"
     CDS             complement(5454..6677)
                     /locus_tag="VU534_001497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HEU1514070.1"
                     /translation="MKRSLDSRVDYSLLLPVFFLLVIGVVAIYIAVSHDYPNNILPIL
                     GQQVAWIALGLVIGFVVMLFNTEFLWKVTPFLYILGLGLMILPIVFYNPSLVASTGAK
                     NWVSINGITLFQPSEFMKISYILMLARVIVQFTKKHKEWRRTVPLDFLLIFWMILFTI
                     PVLVLLALQSDLGTALVFVAIFSGIVLLSGVSWKIIIPVFVTAVTGVAGFLAIFISKD
                     GRAFLHQIGMPTYQINRILAWLNPFEFAQTTTYQQAQGQIAIGSGGLFGQGFNASNLL
                     IPVRESDMIFTVIAEDFGFIGSVLVIALYLMLIYRMLKITLKSNNQFYTYISTGLIMM
                     LLFHIFENIGAVTGLLPLTGIPLPFISQGGSAIISNLIGVGLLLSMSYQTNLAEEKSG
                     KVPFKRKKVVLKQIK"
     gene            complement(6714..9164)
                     /locus_tag="VU534_001498"
     CDS             complement(6714..9164)
                     /locus_tag="VU534_001498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DnaQ family
                     exonuclease/ATP-dependent helicase"
                     /protein_id="HEU1514071.1"
                     /translation="MKTIGNRYVVVDLEATSTGSKAKIIQVGIVVIEDGEIVDHYTTD
                     VNPHEPLDAHIKELTGLTNQRLAQAPDFSQVARKIFDLVEDGIFVAHNVQFDANLLAE
                     NLFFEGYELRNPRVDTVELAQVFFPELEKYSLPILCRELGIPLKHAHTALSDAQATAE
                     LLLFLRKKMTQLPKGLLERLLEMADALLYESYLVIEETYRNQSILSSPDLVQVQGLYF
                     KKTEASLEPRKLSQDFSKNISLLNLEVREEQESFAKEVGLLLKDEPVSLIQAPTGIGK
                     TYGYLLPALSQSKERQIVLSVPTKILQNQIMEEEGKRLKEVFHTDIHSLKGPQNYLKL
                     DAFYHSLQENDENRLFRRFKMQVLVWLTETETGDLDEIGQLYRYQHFLADLRHDGNLS
                     SQSLFVTEDFWKRSQERAETCKLLVTNHAYLVTRLEDNPEFVSDRLLIIDEVQKILLA
                     LENLLQETYDIQSIIDLIDKALVGEENRVQQRILESIRFECLYLIEQFQSGKSRKNIL
                     DSLDNLHQYFSELEVEDFDELVRYFTAEGDYWLEVTETSQKKIQISSTKSGRTLLSSL
                     LPESCQVLGVSATLEISQRVSLADLLGYPEAKFVKIESRGKQEQEVVMVKDFPLVTET
                     SLEVYAREVAALLVEIQAFQQPILVLFTAKDMLLAVSDLLTVSHLAQYKNGDVHQLKK
                     RFEKGEQQILLGAASFWEGVDFSSHPSVIQVVPRLPFQNPQEPLTKKINQELNQEGKN
                     AFYDYQLPMAIIRLKQALGRSMRREYQRSLTLILDRRIVGKRYGKQIVASLAEEATVK
                     TISRSEVDEAIDRFFNEL"
     gene            complement(9364..10293)
                     /locus_tag="VU534_001499"
     CDS             complement(9364..10293)
                     /locus_tag="VU534_001499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006154193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HEU1514072.1"
                     /translation="MEKIVITATAESIEQVEQLLEAGVDRIYVGEKDFGLRLPTTFSY
                     DQLREIAKLVHDAGKELIVAVNALMHQDMMDRIKPFLNFLEEIKTDYITIGDAGVFYV
                     VNRDGYSFKTIYDASTMVTSSRQINFWGQKAGASEAVLAREIPSAELFKMPEILEIPA
                     EVLVYGASVIHHSKRPLLQNYYNFTHIDDEKTHKRDLFLAEPSDPESHYSIFEDNHGT
                     HIFANNDLDLMIKLTELVEHGFTRWKLEGLYTPGQNFVEIAKLFIQARSLIQEGNFSH
                     AQAFLLDEEVRKLHPKNRFLDTGFYDYDPDMVR"
     gene            10433..10720
                     /locus_tag="VU534_001500"
     CDS             10433..10720
                     /locus_tag="VU534_001500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001145225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3270 domain-containing protein"
                     /protein_id="HEU1514073.1"
                     /translation="MPVRKLQSYEVDYQEELNQQLPHYQAYTPEAQSDANLKEILFFI
                     NIAVFCICIAIFSFIFLALKLSTALAFAAAIGFSLLVLKVQRSIIKRKRRR"
     gene            complement(10754..12088)
                     /gene="ciaH"
                     /locus_tag="VU534_001501"
     CDS             complement(10754..12088)
                     /gene="ciaH"
                     /locus_tag="VU534_001501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000491790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     CiaH"
                     /protein_id="HEU1514074.1"
                     /translation="MFSKLKKTWYADDFSYFIRNFGVFTLIFSTMTLIILQVMHSSLY
                     TSVDDKLHGLSENPQAVIQLAINRATEEIKDLENARADASKVEIKPNVSSNTEVILFD
                     KDFTQLLSGNRFLGLDKIKLEKKELGHIYQIQVFNSYGQEEIYRVILMETNISSVSTN
                     IKYAAVLINTSQLEQASQKHEQLIVVVMASFWILSLLASLYLARVSVRPLLESMQKQQ
                     SFVENASHELRTPLAVLQNRLETLFRKPEATIMDVSESIASSLEEVRNMRFLTTSLLN
                     LARRDDGIKPELAEVPTSFFNTTFTNYEMIASENNRVFRFENRIHRTIVTDQLLLKQL
                     MTILFDNAVKYTEEDGEIDFLISATDRNLYLLVSDNGIGISTEDKKKIFDRFYRVDKA
                     RTRQKGGFGLGLSLAKQIVDALKGTVTVKDNKPKGTIFEVKIAIQTPSKKKK"
     gene            complement(12078..12752)
                     /gene="ciaR"
                     /locus_tag="VU534_001502"
     CDS             complement(12078..12752)
                     /gene="ciaR"
                     /locus_tag="VU534_001502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator CiaR"
                     /protein_id="HEU1514075.1"
                     /translation="MIKILLVEDDLGLSNSVFDFLDDFADVMQVFDGEEGLYEAESGV
                     YDLILLDLMLPEKNGFQVLKELREKGITTPVLIMTAKESLDDKGHGFELGADDYLTKP
                     FYLEELKMRIQALLKRSGKFNENTLTYGNIVVNLSTNTVKVEDTPVELLGKEFDLLVY
                     FLQNQNVILPKTQIFDRLWGFDSDTTISVVEVYVSKVRKKLKGTTFAENLQTLRSVGY
                     LLKDVQ"
     gene            complement(12861..15407)
                     /locus_tag="VU534_001503"
     CDS             complement(12861..15407)
                     /locus_tag="VU534_001503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001149089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M1 family metallopeptidase"
                     /protein_id="HEU1514076.1"
                     /translation="MQAVEHFIKQFVPEHYDLFLDLSRETKTFSGKVTITGQAQSDRI
                     SLHQKDLEITSVEVAGQARPFTVDHDNEALHIELAEAGQVELVLAFSGKITDNMTGIY
                     PSYYTVDGVKKEVLSTQFESHFAREAFPCVDEPEAKATFDLSLRFDQAEGELALSNMP
                     EIDVENRKETGIWKFETTPRMSSYLLAFVAGDLQGVTAKTKNGTLVGVYSTKAHPLSN
                     LDFSLDIAVRSIEFYEDYYGVKYPIPQSLHIALPDFSAGAMENWGLVTYREVYLVVDE
                     NSTFASRQQVALVVAHELAHQWFGNLVTMKWWDDLWLNESFANMMEYVCVDTIEPSWN
                     IFEDFQTGGVPLALERDATDGVQSVHVEVKHPDEINTLFDGAIVYAKGSRLMHMLRRW
                     LGDADFAKGLHAYFEKHQYSNTIGSDLWDALGQASGRDVAAFMDSWLEQPGYPVLTVK
                     VENDVLKISQKQFFIGENEDKNRLWVVPLNSNWKGLPDTLETESIEIPGYAALLAENE
                     GALRLNTENTAHYITDYQGDLLAAVLAELETLDNTSKLQIVQERRLLAEAGHISYADL
                     LPVLDKLAKEESYLVVSAVSQVISALERFIDEGTDAETAFKGLVAKLARHNYDRLGFE
                     AKDGESDEDELVRQLAVSMMIRSNDAEASQVASQIFATHKENLAGLPAAIRSQVLINE
                     MKHHETKDLLALYLDTYTHATDAVFKRQLAAALAYSTDADNIQNLITSWKDKFVVKPQ
                     DLSAWYYQFLAHQATQKTAWSWARENWAWIKAALGGDMSFDSFVILPAHVFKTQQRLA
                     EYKEFFEPQLSDLALSRNIGMGIKEIAARVDLISREKAAVEAVVLQYGNA"
     gene            complement(15530..15970)
                     /locus_tag="VU534_001504"
     CDS             complement(15530..15970)
                     /locus_tag="VU534_001504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HEU1514077.1"
                     /translation="MIPQEMWNKYKQINPLIGDEIDAWAFGVEPDLLADLVFKGEKTA
                     TASAYDLYVLEDEPLPQVGTFDVILDSQNQAVCIVEITKVSVKPFNRVSADHAYKEGE
                     GNKTLVYWRQVHEDFFRDCLGEAGLTFTPESKVVLEEFRKVYPL"
     gene            complement(15945..16814)
                     /locus_tag="VU534_001505"
                     /pseudo
     CDS             complement(15945..16814)
                     /locus_tag="VU534_001505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866471.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PEP-utilizing enzyme, TIM barrel domain protein"
     gene            complement(16792..17292)
                     /locus_tag="VU534_001506"
     CDS             complement(16792..17292)
                     /locus_tag="VU534_001506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000403615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEU1514078.1"
                     /translation="MEIKNHFGVYCVCFENGKLLCIEKTRGPYQHRYDLPGGSQQLGE
                     GLTETLTREVMEETGFTVRSYSNPRIYDVFVREELKNFMVHHVIALYDVEMNESAPQV
                     TISEAVSDGANDSLGYIWMDIQEITEENASPLVLKVKSELLGFPELDKTSYMNWKVND
                     EKSTCP"
     gene            complement(17303..18001)
                     /locus_tag="VU534_001507"
     CDS             complement(17303..18001)
                     /locus_tag="VU534_001507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase"
                     /protein_id="HEU1514079.1"
                     /translation="MTKRVLITGVSSGIGLAQARLFLEKGYQVYGVDQGEKPLLEGDF
                     RFLQRDLTLDLEPIFDWCPQVDVLCNTAGVLDDYKPLLEQTAQDIQEIFEINYIIPVE
                     LTRYYLTQMLENKKGIIINMCSIASSLAGGGGHAYTSSKHALAGFTKQLALDYAEAGI
                     QVFGIAPGAVKTAMTAADFEPGGLADWVASETPIKRWIEPEEIAELSLFLASGKASAM
                     QGQILTIDGGWSLK"
     gene            complement(17994..18260)
                     /locus_tag="VU534_001508"
     CDS             complement(17994..18260)
                     /locus_tag="VU534_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2829 domain-containing protein"
                     /protein_id="HEU1514080.1"
                     /translation="MKNVELKEKNMTFEEILPGLKAKRKYVRTGWGGAENYVQLFDTI
                     EQNGLALEMTPYFLINVSGEGEGFSMWSPTVCDVLATDWVEVHD"
     gene            complement(18326..19252)
                     /locus_tag="VU534_001509"
     CDS             complement(18326..19252)
                     /locus_tag="VU534_001509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase family oxidoreductase"
                     /protein_id="HEU1514081.1"
                     /translation="MRYITLGQDDKELSEIVLGMMRIKDKSVKEVEELVETALSVGIN
                     AFDLADIYGRGRCEELLGLVLKNRPDLREKMWIQSKCGIRIEEFTYFDFSKDYIIKSV
                     DGILQRLKIDHLDSLLLHRPDALMESDQVAEAFNLLYKQGKVRDFGVSNQNPMMMELL
                     KKDVKQPLAVNQLQLSAAFTPGFESAFHVNMEDSQAAMRDGSIFEYCQLHDVVIQAWS
                     VLQFGYFKGNFVGNEKFQALNQVLDRLAIKYGVTSSTIAISWILRYPAKMQAVVGTTN
                     PKHLREVSRAANFSLTRKEWYEIYLAAGNNLP"
     gene            complement(19327..20142)
                     /locus_tag="VU534_001510"
     CDS             complement(19327..20142)
                     /locus_tag="VU534_001510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1514082.1"
                     /translation="MKKMKYYEETSALLHEFSEENQKYFEELWESFNLAGFLYDEDYL
                     REQIYLMMLDFSEAERDGMSAEDYLGKNPKKIMKEILKGAPRSSIKESLLTPILVLAV
                     LRYYQLLSDFSKGPLLTVNLLTFLGQLLIFLIGFGLVATILRRSLVQDSPKMKIGTYI
                     VVGTIVLLVVLGYVGMASFIQEGAFYIPAPWDSLSVFTISLVIGIWNWKEAVFRPFVS
                     MIIAHLVVGSLLRYYEWMGISNVFLTKVIPLAVLFIGIFVLFRGFKKIKWSEV"
     gene            complement(20146..20466)
                     /locus_tag="VU534_001511"
     CDS             complement(20146..20466)
                     /locus_tag="VU534_001511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000665424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HEU1514083.1"
                     /translation="MKETQLLKGVLEGCVLDMIGQKERYGYELVQTLREAGFDTIVPG
                     TIYPLLQKLEKNQWIRGDMRPSPDGPDRKYFSLMKEGEERVSVFWQQWDDLSQKVEGI
                     KNGG"
BASE COUNT         6212 a         4526 c         3668 g         6245 t
ORIGIN      
        1 ttctagaatg tcttccaaac gaggaaactc tcgtaaacaa agaggtttta gaggtctatt
       61 taccgtggac taaagttgta caagaaaagt gcaaataaga aatctccaga ttaggaacta
      121 tccgtgagtt ctctagtctg gagatttttc aatagacttc gttattggac ggttaccaag
      181 ttactcaaag tacagatttg aagctgcaga taagactggc gaaatcactt taatactaaa
      241 tgaaaatcaa aaagcaaact aagaagctag cctcaggctg tacttgagta cggtaaggcg
      301 acgctgacgt gatttgaaaa gattttcgaa gagtataaaa cactgttttg aggtagtgga
      361 taaatcggct gggcaaaaac tcaatctcag gagaaaatga agtaaatctc cccacaacta
      421 tagaaaaaga tttgattctg ctcctcacac aataaaatct ttttctttta ttaaaaacga
      481 atcgtttcac gtgttttctc atatgaggta acaaagcgat tggttacacc aggctctgcc
      541 acttccaatg cttgagaaat cttgtcaaat gaagcgtgat aatcaaattc tttttcaaaa
      601 atatctaaag cttcgttaaa tgcttcttga atgcgttcat caaatgagcg atagcggtta
      661 gaatattgca agagttgctc tgtcaaagtt gcatattgta caatattata agtttccgtt
      721 tctaaagctt ccatatcatt cgttgcaatt tcaagaactc gggtaacaga ttcaatgtta
      781 atcatttttt gttctaactc aaccattaaa tcctcggtat tattgcttgc cgtaaagaat
      841 aacttcaaga aagtttgtgg aatacctggc agattgcgtt tttccatgta tcgcttgata
      901 gtatggagac gattgacata aacattggcc ttttgacgtg cattaatatc atctttctca
      961 atttgtgtca ggcgctcact aactgaaatt tgctcatctt caatatcttt tagttgagtt
     1021 tgtaaatcct caagattttc ttcaagaact gaataagctt gggttggttc ttcttgattt
     1081 gaagttacct caacaatagc tgcctcaaaa ctctctaatt ctgtctgaat acgacgaaca
     1141 tggcttgcag ctgtctcagg aagtaaatag gtcttgttca aacgtgcaat atcttctccc
     1201 aataaagtat tattctcttt catatgttga agataagttg gaagagttgc aagtagattt
     1261 tccactactt tctgagcagc aatttctcga gtaaaaatat catacaaggc attgatttcc
     1321 tcttgtgcct gtccattctc atattcggca ttatccaatt ccaactgacg aatattctct
     1381 tggtttttct tgaatgcttc ataaagcaag tggaaacgcg cttcaatatc cgtttcaaca
     1441 aaatgataat tagcatcaat tagtttacga taaccggctt ccaaatcctg taattgatct
     1501 ggcaattctg tagaaagcgt cgtaaccaag gctggaacac gatccacaat atgacttaag
     1561 gccaaaatgt gattttctgt attatccaaa atcactgcgg cttccacagg gtcacccgat
     1621 gaattcaagg ttacaaattg tgaaaattca gattggatat tttctaattg tttttcaatt
     1681 tcatccaagg cttgaccata ctgttctgaa ttttcagcaa ctctatgctg aagttcctca
     1741 aataaatcca aagcatgaag aacacgacca ctatttttag attcttgctt ctctaagtct
     1801 gccaaagcat tgcgaattgc cgcaatatct tcttcaatca aagtaatttg actctcaatt
     1861 tggtcaattt gatgactggc cttgagaaaa cgaaatgaat ggttatagcc ttctgcttca
     1921 aagagattat tttcaatatc ggcaaaagag ttgagagata aatcgaccca tttttgattc
     1981 cattcacgga aagccacttg actttgtcca atcaagtgca tattttttac agcttctact
     2041 tcatcattta ctggaagatt gtatagttct tctttttttt cttctagcgc ctctaatctc
     2101 ccctcgtttc gcttacgtag aaagattgcc actacataag ccagaactaa aatgactgca
     2161 attgcaacca ttaaataaat tagttgtcca ttagacatat caaactcctt ttttacttga
     2221 aacaatcgta acgattatat catatttttt agaccaaggg aactacttct ccctattttt
     2281 tagacatcaa gtgtactata gacagcattt tcttcgataa actcacgacg aggctctact
     2341 cgatccccca tcaacatatc aaagatttta tctgcttctg cagcatcatc tacagaaact
     2401 ctagccatca agcgatgttc gggatccatg gttgtttccc acagctgatg atcgtccatt
     2461 tcacctagcc ccttataacg ctgaatagtc ggtttggtac gaccttcact ataacgggct
     2521 aaagcttctt ggagtttgat ttcttgatct gcacccggct ggatatattc tttaatctcg
     2581 cttccaacct tgacaccata gattggtggt tgggcaatat aaacataacc agcttctagg
     2641 attggtttca tataacgata aatcaaggtt aaaagaaggg tacgaatgtg ggctccatcg
     2701 acatcggcat cggtcatcaa aacgagtttt tggtaacggg ctttcgaaac atcaaattct
     2761 gcgccaaatc ctgttcccat ggctgtgaaa agactacgaa tttcttcgtt ggctagaatc
     2821 ttatccatac ttgctttttc aacgttcaaa atcttaccgc gaattggaag gatagcctga
     2881 aactcacggt tacgaccaga tttggctgat ccaccagctg agtctccttc gacgatgaag
     2941 agttctgttt cagcagggtt attagaagaa cagtctgcta gtttccctgg aaggttggaa
     3001 atttccaaac cagatttttt acgtgtgact tcacgcgcac gcttggcagc cacacgagcc
     3061 ttggcagcca aaattccttt ttctacgata cgtttggcaa tctgtggatt ttccatgagg
     3121 aaatcggaga aagcttcact gaagaggcga ttggtaatct tgaccacttc gctatttccc
     3181 aatttggtct tggtttgtcc ttcaaactgt ggatttgggt gtttaactga gataactgca
     3241 gttaagcctt cgcgaacatc ttcccctgtt aaattatctt cattgtcttt cagtaactta
     3301 tttttacgag cataatcgtt gataacacgt gtcaaggctg tacggaaacc ttgttcatgt
     3361 gttccacctt catgggtatg aatattattg gcgaaactca tgacattttc atggtaacca
     3421 gttgtgtact gcatggctac ctcaactgtg atatcatcca tctcaccgtc tgtatagatt
     3481 ggtgtatcaa agattacatc cttgttctcg ttgatatatt caacgtaact agcaatccca
     3541 ccttcataat gataatgctt ggtttgttcc aaaccttggc gcttatctgt aattgaaatt
     3601 tgaagaccgc gatttagaaa ggccaactct tgaatccgtt tatttaattt atcaaaatca
     3661 aagattgttg tttcagtgaa gatttttggg tccggtgtga agtgaacagt tgttcctgtt
     3721 ttatccgtat ctccaactat ttcaagatct gcgacaacat gaccacgacg gtattcttgg
     3781 taatgaatct taccattttt gtgaacatga acgtctaatt gagtggaaag ggcattaact
     3841 actgacgacc ccaccccgtg aagaccacct gaaaccttgt atccaccacc gccgaacttt
     3901 cctccagcgt gaaggactgt aaagacggtc tcaacagcag gacggcctgt tttttcctga
     3961 atatcgactg ggataccacg cccatcatcc acaacagtaa tcgaatcatc tggctcaata
     4021 aaaacttgaa tatggctggc aaatcctgcc aaggcctcgt caattgagtt atcaacaatt
     4081 tcccagacta gatggtgaag accttctttt gaggttgatc caatgtacat ccctggacgc
     4141 atacgaacag cctctaagcc ctctaaaact tgaatttgac tggcatcata atcctgtgcc
     4201 tgcagatttt tgatttcttc tgtcatctta ttcctttttc ttatatgtct aatacttgtc
     4261 ttaaattcac gatactggta aacaagtggg tatcaagtcc tgcagcttga cctgcttcga
     4321 tatcaatcgg ccgatcacca atgacaagac cagagctaat ctgatacttt tctcttaaat
     4381 aaagcatgga ttcgggattt ggctttctct taaagcctga gctagaagtc accacttctg
     4441 taaaataagc tgctatagag gttttttcta aaatttccaa aacctgatca tttcgatgag
     4501 agaccaaaaa atgacggcca ccttgatttg aaatgtcttc caataggtca gaaactcctt
     4561 caaataaaat cgggtgttca agctctctgg cttcattttc cttgtacttt tctaaaaaat
     4621 tctctaaatt gggagcgaat gtctcaatcg caaaaggagt agaaaccttt aaagcttgat
     4681 agacactgtc atggtcttgt gtgataccat acagtgccaa tgtttcaaca aatgcagctg
     4741 ttgaagtttc ataattatcc agtaaagttc cacctaaatc ccagatgtaa tcgtgatatt
     4801 tcataccctt cattatagca tttttttatg aaaaaagcga tgatttccct gagttttcca
     4861 cataaaaaac gagagaataa ctcccgtttt actgattttt accaaagaca tctcgataga
     4921 gcattcctgt tcgtaaactc tctgcgtccc ctcctagttg ctccaccaac tcgtaggcaa
     4981 aggcaagggc tgttgaagga ccccgactgg ttgtcaactg accatctacc actactgttt
     5041 ccttgacgta gtgaccatca aggatttgct cttgaacgcc gtcataacaa gtgtatcgct
     5101 tatttttcaa tatctctgct tgattgaggg caattggtgc cgcacaaatg gctgctagtt
     5161 tcttcccttc ttgctcgaag ctttgcaatt cttgaatcaa ggtctgatta tcacgtaaat
     5221 gtgcagaacc aggcatacct ccaggaagaa caatcatatc atagtctgat aaatctccat
     5281 caaagacatg atctgctctt acttggattg catgcgaacc cgttacttgc tcttcaaaac
     5341 caaccatatc acatgtgata ttggctcgac gcaagacatc tacaactgtc aaggcttcaa
     5401 tttcttcaaa gccctgagct aatataactg ctacttttac catgattttc tccttattta
     5461 atttgtttta atacaacctt tttccgtttg aatgggactt ttccgctctt ttcttcagct
     5521 agattagtct ggtaactcat cgataaaagc aaaccaacac caatcagatt actgataata
     5581 gctgatcccc cttgcgaaat gaaaggcaag ggaatccccg tcaaaggaag tagtccagtc
     5641 acagcaccga tattctcaaa gatgtggaag agcaacatca taatcaaacc tgtggaaata
     5701 taagtgtaga actggttatt tgatttaaga gtaatcttca acatacggta aatcaacatg
     5761 agatagaggg caataaccag gacagagcca ataaagccaa aatcttctgc aataaccgta
     5821 aaaatcatat ctgactctcg aactgggata agcagattcg aagcattaaa tccctgacca
     5881 aataagccac cactcccaat ggcaatctgc ccttgagcct gctggtaagt cgttgtttgg
     5941 gcaaactcaa agggattgag ccaagccaaa atccgattaa tttggtaggt cggcattcca
     6001 atctggtgaa gaaaagctcg tccgtccttg ctaataaaga tagctaagaa accagcaact
     6061 cctgttacag cagtcacaaa tactgggata ataattttcc aagaaacccc tgataataaa
     6121 acgattcctg agaaaatggc tacaaaaacc aaagccgtcc ccaagtcact ttgaagtgct
     6181 aaaagaacta ggactggaat ggtaaagaga atcatccaga aaattaacaa aaagtccagc
     6241 ggaaccgtgc gtctccattc cttatgtttc tttgtaaatt ggacaatgac acgagccaac
     6301 atgaggatat aggatatctt cataaattct gacggttgga atagggtaat tccatttatt
     6361 gatacccagt ttttggcacc cgttgatgca actaagcttg gattataaaa tacaatcggc
     6421 aagatcataa gtcccaagcc taaaatatat agaaaggggg tcaccttcca aagaaattct
     6481 gtattaaaga gcatgaccac aaaaccaatc acaagcccca aggcaatcca ggcgacctgc
     6541 tgccctaaaa tgggcagaat attattggga taatcatgac taacggctat atagatagcc
     6601 accacaccga tgaccagtag aaaaaatact ggcaagagca aactgtaatc gactcttgag
     6661 tcgagagaac gtttcatata tactaacctt atactttcat acaatactat ttatcaaagc
     6721 tcattaaaaa atctatcaat agcctcgtca acttcggatc gagagatggt tttaacagtc
     6781 gcttcttctg ctagagatgc tactatttgt ttgccgtatc gttttccgac gattctccta
     6841 tccaaaataa gagttaagga acgttggtat tcacgtctca tacttcttcc caaagcctgt
     6901 tttaaacgaa taatggccat tggcaattga taatcataaa aggcattttt cccttcttga
     6961 ttcagttctt gattaatctt tttcgtcaag ggttcttgag gattttggaa aggaagcctc
     7021 ggtacaactt gaatcacaga aggatggctt gaaaaatcaa ctccctccca gaaacttgct
     7081 gcaccaagca agatttgttg ttcacctttt tcaaagcgtt tctttagctg atgaacatcc
     7141 ccatttttat actgggccaa gtggctaact gtaagtaaat ccgatactgc tagaagcatg
     7201 tctttagcgg taaagagaac caaaatcggt tgctggaaag cttgaatttc cactagtaaa
     7261 gcagctacct ctctggcata gacttctaag gaggtttctg ttaccagagg gaaatctttg
     7321 accatgacca cttcttgttc ctgttttccc cgagattcaa tcttgacaaa tttagcttca
     7381 ggatagccta aaaggtctgc caaagaaacc ctctgactaa tctcaagagt agccgatact
     7441 cccaagactt ggcaactctc aggaagtaaa gaggacagaa gagtacggcc tgattttgta
     7501 gaagaaatct gaattttctt ttgactcgtt tcagttactt caagccagta atcaccttca
     7561 gctgtaaaat agcgaaccag ctcatcaaag tcttctactt ccaattctga aaaatactga
     7621 tggagattgt ccagagaatc taagatattt ttcctagatt tgccagactg aaattgttct
     7681 atcaagtaga gacactcaaa gcgaatactt tctagtatcc gttgttgaac cctgttttct
     7741 tctcctacta aagccttatc aattaaatcg ataatagatt gtatatcgta ggtctcttga
     7801 agcagatttt ctagagctaa caaaatcttt tggacttcat caataatcag taaacggtca
     7861 ctgacaaatt caggattatc ttcaagtctg gttacgagat aggcatgatt agtcactaaa
     7921 agcttgcaag tctctgccct ttcttgacta cgtttccaaa aatcttccgt cacaaataag
     7981 ctctgggatg ataaattccc atcatgacga aggtctgcta gaaaatgttg gtaacggtag
     8041 agttgcccga tttcatccaa atctcctgtc tctgtctcag taagccagac caagacttgc
     8101 attttaaagc gtctaaataa gcgattttca tcattttcct gcaaggaatg ataaaaggca
     8161 tccaacttca gataattttg tggtcccttt aagctatgaa tatctgtatg gaacacttcc
     8221 ttgaggcgtt taccttcttc ttccatgatt tgattttgaa gaatctttgt cggaacacta
     8281 agaacaattt gtcgctcttt ggattgagat aaagcgggta agagatagcc ataggttttc
     8341 ccaatccctg tcggcgcttg aatcagagag acaggttcat ctttcaatag caagccaacc
     8401 tctttagcaa aactttcttg ttcctccctc acttcaaggt tcaacagaga aatattttta
     8461 gaaaagtctt gagatagttt tcgtggctcc agagaagctt ccgttttctt aaaatataga
     8521 ccttgaactt ggaccaagtc tggagaactc aggatagatt ggttgcgata agtttcctca
     8581 ataaccaggt aggactcata taggagagcg tcagccattt ccagcaagcg ttccaagaga
     8641 cctttaggaa gctgggtcat ctttttccgt aaaaaaagaa gtaattctgc tgtagcttgg
     8701 gcatctgaaa gggctgtgtg tgcgtgttta agaggaattc ctaattctcg acacaaaatc
     8761 ggcaagctat atttttccag ttcagggaaa aagacctggg ccaattcgac cgtatcaaca
     8821 cgagggtttc ttagctcata gccttcaaaa aataaatttt ccgccaagag attagcatca
     8881 aactgaacat tatgggctac aaaaatccca tcctccacca agtcaaatat ttttctggca
     8941 acttgcgaaa aatcaggtgc ttgcgccaga cgttggtttg tcaatcctgt cagttctttg
     9001 atatgagcat ccaagggttc atgtggattg acatccgtcg tatagtgatc gacgatttct
     9061 ccgtcctcaa tcacgacaat tcccacttgg ataattttag ccttactacc tgtgctagtt
     9121 gcctctaaat ccaccacaac atagcgatta ccaatcgttt tcattataaa aaattatacc
     9181 aaaaaaaggg ccatttggca cctgcaaaca taggataatt ttcaaactca agaacactac
     9241 ttttcttaaa aatcccatcg aatagagcat tctagcctgc tgatttttgt aaaatagtga
     9301 agaaatacga aaaattgaga gaagaaatgt ttgcatcttc cttctctcaa cgaatcatgt
     9361 attttatcta accatgtcag gatcgtagtc ataaaatcct gtatcaagga aacggttttt
     9421 agggtgaagt ttacgaactt cttcatccag caagaaggct tgagcatgac taaagttgcc
     9481 ctcttgaatc aagctacgcg cttggataaa gagttttgca atctcaacaa agttctgacc
     9541 aggagtgtag agcccttcta gtttccagcg agtaaagcca tgctccacca attctgttaa
     9601 tttgatcatc aaatcaaggt cattgttggc aaagatatgg gtcccatgat tatcttcaaa
     9661 aatggaatag tggctctctg gatcacttgg ctcagccaag aagaggtcgc gtttatgcgt
     9721 cttttcatca tcgatatgtg taaagttata gtagttttgc aagagtggac gtttagaatg
     9781 atggatgacg ctagcaccgt aaaccaaaac ttcagcagga atttccaaaa tctctggcat
     9841 tttgaaaagt tcagctgatg gaatttcacg cgccaaaaca gcctcagatg cgccagcctt
     9901 ttgtccccag aagttaatct gacgactgct agttaccatg gttgaagcat cgtagatggt
     9961 cttaaatgaa taaccatcgc ggttaactac gtaaaagacg cctgcatccc caatcgtaat
    10021 atagtctgtc ttgatttctt ccaagaagtt taagaaaggc ttgatacggt ccatcatatc
    10081 ttggtgcatg agagcattga ccgcaacgat caattcctta ccagcatcat gaaccaactt
    10141 agcgatttca cgtaattggt cataactaaa ggtcgttggc agacgaagac caaaatcttt
    10201 ctcaccgaca tagatacggt ctacgccagc ttcgagtagt tgttcaactt gttcaatact
    10261 ttcagcagtt gctgtaatga caatcttttc cataagaaaa attataccac atttctccaa
    10321 aatcagccat gctttgaaaa tgaaaaggga ctttattctt tttgtaacct ttctgtaata
    10381 attctctgcc gaaaaaatga taaaataggt atgtactgtt aaggagagaa tcatgcccgt
    10441 aagaaaatta caatcctatg aggtagacta tcaagaagaa ttaaaccagc agcttcctca
    10501 ttaccaagct tatacacctg aagcgcaatc tgatgccaat ctcaaggaaa tcctattttt
    10561 tattaatatc gctgtttttt gtatctgtat tgctatcttt agttttatct ttttagcatt
    10621 aaaattatca actgctcttg cctttgccgc agcaatcgga ttcagcttac ttgttttaaa
    10681 agttcaacgg tctattatca aacgaaaacg tagaagataa atccaaaata tcgccccaat
    10741 tggagcgata tttttatttt ttctttttag atggtgtctg aatggcaatc ttcacttcaa
    10801 agattgttcc cttgggttta ttatctttga cagtaacagt tccttttaga gcatctacaa
    10861 tttgcttggc tagggataat cctaaaccaa aaccaccttt ttgccgggtt ctagccttgt
    10921 ctactcgata aaaacggtca aaaattttct ttttatcttc tgtcgaaata ccgattccat
    10981 tatcagaaac aagtaaataa agattgcgat cggtcgccga gataagaaaa tcaatttcac
    11041 catcctcctc agtatacttg acggcattat cgaaaagaat ggtcatcagt tgtttcagaa
    11101 gaagctgatc tgtgacaatt gttcgatgga tacgattttc aaaacggaag acacgattat
    11161 tttccgaagc aatcatctcg tagtttgtga aagttgtatt aaaaaagcta gttggaactt
    11221 ctgcaagctc cggcttaatc ccatcatctc tccgagctaa gttcagcaag cttgtcgtta
    11281 aaaaacgcat atttcggact tcttccaaac tcgatgcaat gctttcgctc acatccataa
    11341 tggtagcttc tggcttacga aaaagggtct ctaagcgatt ttgcaaaact gcgagtggag
    11401 ttcgtaactc atgactggca ttttccacaa aagactgttg cttctgcata ctctcaagca
    11461 ggggcctaac actgacccta gctagataga gactggcaag taaagacaaa atccagaaac
    11521 tagccatcac gaccacaatc aattgctcat gcttttgact agcctgttcc aactgactgg
    11581 tattaatcaa gacagcagca tacttgatat tggttgaaac cgaactaata ttggtctcca
    11641 tcaaaatcac acgatagatt tcttcctgcc catagctatt aaaaacctga atctggtaga
    11701 tatgtcctag ttctttcttt tctaacttaa tcttatccaa gcccaaaaat cgatttccag
    11761 aaagaagttg agtaaagtct ttatcaaaga gaatgacttc cgtattggaa ctgacattag
    11821 gttttatttc tactttacta gcgtccgccc tagcattttc taaatcttta atctcttctg
    11881 ttgccctatt tatagccagc tgaataactg cttgaggatt ttcactcagt ccatgaagct
    11941 tatcgtccac cgaagtataa agactcgaat gcatgacttg taaaataatc agagtcattg
    12001 tagaaaaaat cagggtgaag acaccgaagt tgcggataaa ataactaaag tcatccgcat
    12061 accatgtttt tttaagttta ctgaacatct tttaaaagat acccaacact acgcaaagtt
    12121 tgcaaattct ctgcaaaagt ggttcccttt aatttcttac ggacttttga aacatagact
    12181 tcgacaaccg aaatcgttgt atcactatca aatccccata gacggtcaaa aatctgcgtc
    12241 ttaggcaaaa tcacattttg attttgaagg aaataaacta gtaaatcgaa ctctttcccc
    12301 agcaattcga caggagtatc ttcaacttta acggtattgg ttgataaatt aaccacgata
    12361 ttcccataag tcaaggtgtt ttcattaaac ttccctgaac gtttgagaag ggcctgaatc
    12421 cgcattttaa gttcttctag gtagaaaggt ttggtcagat aatcatccgc tcccagttca
    12481 aatccatgtc ccttgtcatc caaactttcc ttggcagtca taatcagaac tggtgtcgta
    12541 attccctttt cacgcaattc ttttaagact tggaaaccat ttttttctgg caacatcaaa
    12601 tccagcaaaa tcaagtcata gacaccactc tcagcttcgt agagaccttc ttctccatca
    12661 aatacctgca taacatccgc aaaatcgtct aaaaagtcaa atactgaatt tgacagacct
    12721 aggtcatcct caaccaataa gatttttatc atgagaaact cctccttatt aaaactatta
    12781 taccaaattt gccttaaaaa aaactcaact ctctgcattt tacatgagat agctgagttt
    12841 tctttttatt ttaggcttat ttatgcattt ccgtattgaa gaacaactgc ttcgactgca
    12901 gctttttcac ggctaatcaa gtcaacacgc gctgcaattt ccttgattcc cataccgatg
    12961 ttacggctaa gagcaaggtc agaaagttgc ggttcaaaga actccttgta ttccgccaag
    13021 cgttgctgag tcttaaatac atgagcagga aggataacaa agctatcaaa gctcatatct
    13081 cctccaaggg ctgccttaat ccaagcccag ttttcacgcg cccaagacca agctgttttc
    13141 tgagttgctt gatgagctag gaattggtaa taccaagcag acaagtcctg tggtttgacc
    13201 acaaatttgt ccttccaaga agtaatcagg ttttggatat tatccgcatc tgtactgtat
    13261 gcaagagctg ctgccaactg gcgtttaaag acagcatctg ttgcgtgagt ataagtatca
    13321 agataaagtg ctaacaagtc tttagtctca tgatgtttca tctcattaat cagaacttgt
    13381 gagcgaatag ctgctgggag tcctgcaaga ttctccttgt gtgttgcgaa gatttggcta
    13441 gcgacttgac tagcttctgc atcatttgag cgaatcatca tcgaaacagc cagctgacga
    13501 accaattcat cctcatctga ttctccgtct ttagcttcaa aaccaagacg gtcatagtta
    13561 tgacgagcca atttagcaac cagtcctttg aaggctgttt cagcatccgt tccttcatca
    13621 ataaagcgct caagggctga aatcacttga gaaacagctg aaaccaccag ataagactct
    13681 tccttagcaa gtttatcaag aactggaagc aagtctgcat aagaaatgtg ccctgcctca
    13741 gccaacaaac gacgttcttg aacaatttgc agtttgcttg tgttatcaag tgtctctagc
    13801 tcagcaagaa cagctgctaa caagtctcct tgatagtcgg taatatagtg ggcagtattt
    13861 tcagtgttga gacgaagagc tccttcattt tcagcaagaa gagctgcgta gccagggatt
    13921 tcgatacttt cagtttcgag tgtatcaggc aagcctttcc agttgctatt gaggggcacc
    13981 acccagagac ggttcttgtc ttcgttctca ccgatgaaga attgtttttg tgaaatcttc
    14041 aagacatcat tttcaacttt aacagtaaga actgggtaac caggctgttc caaccaagaa
    14101 tccatgaagg ctgcgacatc acgtcctgac gcttgaccaa gggcatccca aaggtcacta
    14161 ccaatggtgt tgctgtattg gtgtttttca aagtaggcgt gcaaaccttt agcaaaatca
    14221 gcatctccta gccaacggcg aagcatgtgc atgagacggc ttcctttggc atagacgata
    14281 gcgccgtcaa agagtgtatt gatttcatct ggatgtttaa cttcgacgtg gacagactga
    14341 acgccatcag tagcgtcacg ttcaagagca agaggtactc cacctgtttg gaaatcttca
    14401 aagatattcc agcttggttc gatggtatcc acacagacgt attccatcat attagcgaaa
    14461 ctttcattga gccaaaggtc atcccaccat ttcatagtca cgaggttccc aaaccattgg
    14521 tgagccaatt catgggccac aacaagggca acttgttgac ggctagcaaa tgtagagttc
    14581 tcatcgacaa ccaagtaaac ttcacggtag gtcacaagac cccagttttc catagcacca
    14641 gctgagaagt caggaagggc gatgtggaga gattgaggaa ttgggtactt aactccatag
    14701 taatcttcgt aaaactcgat agagcgaaca gcgatatcca gtgagaaatc aagatttgaa
    14761 agtggatgtg ctttggttga gtagacacct accagggtac catttttagt tttagcggtc
    14821 accccttgca aatcaccagc aacaaaggcc aacaagtaag aagacatgcg aggtgttgtc
    14881 tcaaacttcc agatacctgt ttccttacgg ttttcaacat cgatttctgg catgtttgac
    14941 aaggccaatt caccttctgc ttggtcaaag cgaagagaga ggtcaaaagt tgctttggct
    15001 tcaggctcat ccacacatgg gaaagcttcg cgcgcaaaat ggctctcgaa ctgagtagac
    15061 aagacctcct tcttgactcc atcaactgta taataagaag ggtaaatccc tgtcatgttg
    15121 tctgtaattt taccagaaaa ggcaagaacc aattcaactt gaccagcctc agccaattcg
    15181 atatgaaggg cttcattgtc atggtcaact gtaaatggac gagcttgacc tgcaacttct
    15241 acagaggtga tttccaaatc tttttggtgg agggagatgc ggtcactctg tgcttgacca
    15301 gtgatggtca ctttcccaga aaaagtcttg gtctcacgac tcaaatctaa aaataaatca
    15361 taatgttcag gaacaaattg cttaataaaa tgttcaactg cttgcatagt tttctcctat
    15421 tctaagttta agagctgctg ctcttcttca aacaaactta ttatatcata ttttgcttca
    15481 gaaaaaagga ttggacagcg atttccaaaa ctttcttcct tctaatagtc tacagtgggt
    15541 agaccttgcg aaattcttct aaaacaacct tgctttcagg tgtaaaagtc aatcctgctt
    15601 cacccaagca gtctctgaaa aaatcctcat gaacctggcg ccaatagaca agtgtcttgt
    15661 ttccctcacc ttccttatag gcatggtcag ctgacactcg attgaagggt ttaacagaaa
    15721 cctttgtaat ttcgacaatg cagacagcct gattttgact atctaaaatg acatcgaagg
    15781 tccctacttg gggaagtggt tcgtcttcta gcacatagag gtcataggct gatgctgttg
    15841 ctgtcttttc tcctttaaac accaaatccg ctaaaaggtc tggttcaact ccaaaagccc
    15901 aggcatcgat ttcatctccg atcaaaggat tgatttgctt gtatttattc cacatttctt
    15961 gcggtatcat gggtgctcct ttgtaatttt ttactttctt cttttatgtg tttaagatga
    16021 tctggatggt caatctctaa atcaaaaatc tctggaatag aactgtagtg gataatgcac
    16081 ttgataccca actgattcat tttttgtatg aaagaagtat tcagatagcc tgctacagca
    16141 aaatcaatct tgttctttct tgctttatcc tgcatatctc ttagcatatc taacattatt
    16201 ggactttcca tatcatgcca ttgactgttt ctcatagtcg caaaaacaaa ggaagtcaaa
    16261 tcattcattc caactacaat ctttgaaatg cccgtttcca gtatactaga taagtcaaaa
    16321 tacgctgacg gtaattcaat catcgttccg actttcccag taaaaccctg ctgacgcaat
    16381 actgtaatag cttgttttaa ttagtcggca tcattgacaa aaggaaagat aacagataga
    16441 ttggggttgg tttgataaac ttctgtaacg acatgtgctt cagcctgaaa ttcatccaaa
    16501 cacgccagta aacgcctagt tcctctatag ccaaacaagg gatgcccttc gtcaaaaaac
    16561 tctttagtcc ccactaaaca attggcttct gtattcgtta attcagtaaa acgataccaa
    16621 acttccttac ctaagtaaaa ggagcaaata gtatcaagat aatctttcac aaattcctga
    16681 caactttgta atagtatatt ttgattgagc tctctcaata agtattcccc acgaatcatg
    16741 ccgacgtggt gaaatagttg aggataaatt ttttcaagaa ttttttcgcc actaagggca
    16801 agttgatttc tcatcattca ccttccaatt catgtaagaa gtcttgtcca gttctggaaa
    16861 tcctaataat tcagacttaa ccttcaagac taatggcgat gcattttctt ctgtaatctc
    16921 ttgaatatcc atccaaatat atccaagtga atcattcgca ccatcagaca cagcttccga
    16981 aatcgtaact tgaggtgcac tctcattcat ttcaacatca tacaaggcta tgacatggtg
    17041 aaccataaaa ttttttaact cttccctgac gaaaacatcg tagattcgag gattagagta
    17101 gcttctaaca gtaaatcccg tctcttccat aacttctcta gtcagcgttt ccgtcagtcc
    17161 ttcaccaagt tgctgactgc ctccaggtag atcataccga tgttgataag ggcctctcgt
    17221 tttttcaatg caaagtaact ttccattttc aaagcaaaca cagtagaccc caaagtgatt
    17281 tttgatttcc atccaactcc tcctacttca aagaccagcc accatctatt gtcaagattt
    17341 gtccttgcat ggcgctcgct tttccacttg ctaaaaaaag actaagctct gctatttcct
    17401 ctggctcaat ccagcgcttg attggggttt cactagccac ccagtcagcc aaaccacctg
    17461 gttcaaaatc cgcagcggtc atagctgtct tgactgctcc tggagcgata ccaaagacct
    17521 gaatcccagc ttcagcatag tctagagcca actgcttggt gaagccagcc aaggcatgct
    17581 tggatgaagt ataggcgtga ccacctccac ctgctaggct agaagcaatg gaacacatat
    17641 tgatgatgat tcccttttta ttttccagca tttgtgtcaa ataataccga gtcaactcta
    17701 ctggaataat gtagttgatt tcaaaaatct cttgaatgtc ctgcgccgtt tgttccaaca
    17761 gtggtttgta atcatccaaa actccagcag tattacacaa aacatccacc tgagggcacc
    17821 agtcaaaaat aggttccaag tccaaggtca aatctctctg taaaaagcga aaatcaccct
    17881 ctaagagtgg cttttcacct tggtcaactc cataaacttg atagcccttc tctaaaaaga
    17941 ggcgagcttg agccaatccg atccctgaac tcactcctgt aatgagtaca cgtttagtca
    18001 tgcacttcta cccaatccgt tgccaaaaca tcacaaactg tcgggctcca catggaaaaa
    18061 ccttctcctt cgccagaaac gttgattagg aaataaggtg tcatttcaag tgcaagccca
    18121 ttttgctcga tggtatcaaa gagttggaca tagttttccg cacctcccca accagttcgt
    18181 acatattttc tcttagcctt taacccaggc aggatctctt caaatgtcat gtttttctcc
    18241 tttaattcta cattcttcat ttaattatag caaaaaaccg ctttatacgg ctttttgaat
    18301 gtgagttatt caaacctgct actacttacg gcaaattatt ccctgcagca agataaattt
    18361 cataccattc ttttcttgtt aagctaaagt ttgccgctcg gctaacttct ctcaagtgct
    18421 taggatttgt tgtacctacg actgcctgca tttttgctgg ataacgcaat atccaagaaa
    18481 tggcaatagt tgaagaggtt actccatatt taatagctaa acgatcaagt acttgattta
    18541 aagcttgaaa tttctcattt ccaacaaaat tccctttaaa atacccgaat tgtaagacag
    18601 accatgcttg aatgaccaca tcgtgtaatt ggcaatattc aaaaatgctg ccatctcgca
    18661 tagctgcttg actatcttcc atattaacat gaaaagctga ttcaaatcct ggagtaaaag
    18721 ccgcactcaa ttgtagctga ttaacagcta acggctgctt gacatctttt ttaagcaact
    18781 ccatcatcat aggattttga ttagaaactc caaaatctcg aactttacct tgtttataaa
    18841 ggagattaaa ggcttctgct acttggtcag attccatcaa agcatctggt cgatgaagga
    18901 gcaagctatc tagatgatca atcttcaatc tttgcaaaat accgtctact gattttataa
    18961 tatagtcctt agaaaaatca aaataggtaa attcttcaat gcgaatgcca catttggact
    19021 gaatccacat cttttctctt aaatctggac gattttttag gacaagacct aacagttctt
    19081 cacaacgacc acgaccataa atatcagcca agtcgaaggc attgattcca acagaaagtg
    19141 ctgtttctac aagctcttca acttctttta cagatttatc ttttattctc atcattccga
    19201 gaacaatttc tgataattct ttgtcatctt gaccaagagt tatgtatctc atcaaatttt
    19261 tctcctttaa tttctaacat tcttcccttc attataacaa aaaaccgctt tgcaacgact
    19321 ttttgactat acttcactcc attttatctt cttaaaccca cggaacaaga caaagattcc
    19381 aataaagagg acagctaaag gaataacttt tgtaaggaaa acatttgaaa ttcccatcca
    19441 ctcataataa cggagcagag aacccaccac aagatgggca ataatcatac tgacaaatgg
    19501 acgaaagacc gcttctttcc aattccaaat accgataact agcgaaatcg taaagacaga
    19561 caaactatcc cagggagccg gaatataaaa ggctccttct tgtatgaagc ttgccattcc
    19621 tacatatcct aaaacaacta gaagaactat agtcccaaca acaatgtaag tgccaatttt
    19681 cattttagga gaatcttgga ctaaacttct tcgtaaaatt gtggccacaa gtccaaatcc
    19741 aatcagaaaa ataagaagtt gccctaaaaa tgtgagcaaa ttgactgtta agagaggacc
    19801 tttagaaaaa tcacttagta gttgataata acgtaatacc gccaggacaa gaattggcgt
    19861 caaaagggac tctttgatag aactgcgagg tgctcccttg agaatctctt tcattatttt
    19921 tttaggattc ttacctagat aatcctctgc actcatgcca tctcgttctg cttctgagaa
    19981 atctagcatc atcaaataga tctgctctct gagatagtct tcatcataga gaaatccagc
    20041 aagattaaaa ctttcccaca actcctcaaa atacttttga ttctcctcag aaaactcatg
    20101 tagcaaagcg cttgtttctt cgtaatactt cattttcttc atggtttaac ccccattctt
    20161 aatcccttct actttttgac tcaaatcgtc ccattgttgc caaaagactg agacacgctc
    20221 ttctccttct ttcattaatg aaaaatactt ccgatctgga ccatctggcg acgggcgcat
    20281 gtcgcctctt atccattgat ttttttctaa cttttgcaac aaaggataaa tagttcctgg
    20341 aacgatagta tcaaatccag cctctcgcaa agtctgaacc aactcataac cataccgctc
    20401 tttttgacca atcatatcca agacacaacc ttcaagaaca ccttttaata gctgagtttc
    20461 tttcatcact tctcccttct aatctatttt gtaataccta ctagtgactt cacctatagt
    20521 atatcacttc tacactagtt tgtaaagcat aatagttaat actcttcgaa aatctcttca
    20581 aaccacgtca gcgtcgccct accgtatgta tggttactga cttcgtcagt ttcatctaca
    20641 acctcaaaaa c
//
LOCUS       DAVFER010000038        20576 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1105170250
            SAMEA2167659-rid19724873.denovo.038, whole genome shotgun sequence.
ACCESSION   DAVFER010000038 DAVFER010000000
VERSION     DAVFER010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2167659
            Sequence Read Archive: ERR388902
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20576)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20576)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928716.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928716.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 04:07:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,118
            CDSs (total)                      :: 2,073
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 120
            CDSs (without protein)            :: 120
            Pseudo Genes (ambiguous residues) :: 0 of 120
            Pseudo Genes (frameshifted)       :: 67 of 120
            Pseudo Genes (incomplete)         :: 47 of 120
            Pseudo Genes (internal stop)      :: 34 of 120
            Pseudo Genes (multiple problems)  :: 23 of 120
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20576
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2167659-rid19724873.denovo.038"
                     /strain="1105170250"
                     /db_xref="taxon:1313"
     gene            <1..372
                     /locus_tag="VU534_001512"
     CDS             <1..372
                     /locus_tag="VU534_001512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001235657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEU1514084.1"
                     /translation="FCLVLVSIDYINCLSETTDKNWHKSDRIFVTNTGKTVHSSILSK
                     SLQRANERLKKPIPKHLSPHIFRHTTISILSENKIPLKTITDRVGHPDSEVTTSIYTH
                     VTKNMKDEAINVLDKVMKKIF"
     gene            complement(692..868)
                     /locus_tag="VU534_001513"
     CDS             complement(692..868)
                     /locus_tag="VU534_001513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000346914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1514085.1"
                     /translation="MDFLNHSFDTKKVINTKINAVNSKNNVGKNFIDVYREMKEVPNN
                     KIHQSKVNVALIKK"
     gene            complement(871..2061)
                     /locus_tag="VU534_001514"
     CDS             complement(871..2061)
                     /locus_tag="VU534_001514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000123149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1514086.1"
                     /translation="MTAEIGILNKNGVVLASDSAVTLSDGKNSKVFNSARKLFTLSKE
                     HSVGIMIYGNASFMEIPWEVILNEFKQAIGTDLLDNTAQYVEKLIEFLISFKHLQVED
                     LLRNYIVRSTRSILDSIAYEAQETADLRVSNGETITLDDFNKILLNAITNFSLEISKV
                     EAESNFEFFEAELELIKSIVDDVFKSFPHTDDEVEVIAKSLYKAIFIGYDSTNITGLV
                     IAGYGTDEIFPSIRQIELYGIFSKRLIWKVINESVINHHKTCHIIPFAQSEMVETIMN
                     GIDPNLNVYIAEQVSSVMEKNGLGDEIENIFENISSIQQKYYINPIIDLIGMQPLNEM
                     ASTAKTFIELTSFKRKIVNTLETVGGPVDVLAISKGEGPIWIDRKYYFDIDKNLDYRM
                     RKES"
     gene            complement(2079..2372)
                     /locus_tag="VU534_001515"
     CDS             complement(2079..2372)
                     /locus_tag="VU534_001515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000794247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU1514087.1"
                     /translation="MKNNAIGSNWKDVRAELFSKEEILESDMRVAIMSELIEARNEKG
                     ISQKKLEEMSGVSQPVIARMETGKTSPQLDTVLKVLASLGKTLAVVPLEHEQV"
     gene            complement(2362..2727)
                     /locus_tag="VU534_001516"
     CDS             complement(2362..2727)
                     /locus_tag="VU534_001516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000551587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HEU1514088.1"
                     /translation="MHNIYFYKDKNGNEPVFDYMRELTSKKGKDSRIKLNKINDYIEL
                     LSQHGTRAGEPYIKHLDAEIWELRPLRDRILFVAWMDGSFVLLHHFMKRTQKTPKREI
                     EQAKRELADLKERGLDNEK"
     gene            complement(2924..3334)
                     /locus_tag="VU534_001517"
     CDS             complement(2924..3334)
                     /locus_tag="VU534_001517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000162610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1514089.1"
                     /translation="MTKKKIERISVIHREKILWLKWYFMRDKEQPKYSVLERKMFDAA
                     KNQDMLAYQKYATIKQITDIRVQTSEADILEAVKEVYVYNHMNVIGACQRILFISQSP
                     AYDKLNKWFNIYSDLYFSVVPLPKMGVYHEMVGI"
     gene            complement(3352..3663)
                     /locus_tag="VU534_001518"
     CDS             complement(3352..3663)
                     /locus_tag="VU534_001518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001113833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1514090.1"
                     /translation="MPEFIIVEGNNDLGEFFQIDGELFSDNELLENLKKWREWEVPVI
                     IDDWCNRILNEDETEILYFPTHEDKMNYIRVEKDLEPLYHTSNKIYATISKSEWLELL
                     N"
     gene            complement(3671..4099)
                     /locus_tag="VU534_001519"
     CDS             complement(3671..4099)
                     /locus_tag="VU534_001519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000918210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /protein_id="HEU1514091.1"
                     /translation="MAGNENDNLTSKQIKFIDAMLTEPTIDKACQKAGVSRATGHKYL
                     KVAAVKKTLRIKQDEMMDKTTQMLYLASSNAVSVLNDIMMDSKVNPFIRTQAAKAILE
                     QSYKTHEIFGVVRQIEELRLEIEEVSKGNQRVTRTQGVIK"
     gene            complement(4146..4796)
                     /locus_tag="VU534_001520"
     CDS             complement(4146..4796)
                     /locus_tag="VU534_001520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000138311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1514092.1"
                     /translation="MTENKDDKLLKMMEKGFVLYSKNGIIKYIEIPEHGSIKLKAQDG
                     QLVYKEVIIGKVYAEQELLKYKKEGENYSQNTAQLLYQQLEKEKNAELANHESKEEPI
                     TADDAAELSLLSSIKLTVAEMREYLEKYKNKPLALRKLEDIMDNDTTLAYIEIDMEQF
                     SQQQRLEKLVHFLDRKIDYFHGGLLINGDKIDLVQHEMIVEGNSEAMDAELQNYLA"
     gene            complement(5045..5929)
                     /locus_tag="VU534_001521"
     CDS             complement(5045..5929)
                     /locus_tag="VU534_001521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000838905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEU1514093.1"
                     /translation="MKSLQSSLGNIETFKLDELCPKHEIQLTQIKGERHVVVGWNENG
                     EAIKEVRCIPPYCEQCQEEQKKQDEEDAIADNLNAKLYMQTYNVLMSNKSYVADEFKT
                     KTFDDFNAVTSEEKRFLEFAKGQVQKYLDGMRGNTLITGGTGIGKTLLSVAIAKGINE
                     GYKTKGEPKSVLFVSLTEMIKQIKEGWNYGKGATLTEFEATELMKSVDYLIIDDLGAK
                     NAVIKPKSDWEQDLLFDVLNNRENTIFNTNLDSDELKIVYNERNYSRILKGLEGNTFK
                     AFGIKYKRYSLNQLKSNM"
     gene            complement(5941..6387)
                     /locus_tag="VU534_001522"
     CDS             complement(5941..6387)
                     /locus_tag="VU534_001522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HEU1514094.1"
                     /translation="MTLDLDNMTQAEFDEVMAEIQLQSPNIFQLISDFVNKKVTSVEI
                     DDLLNMKRAETGKALSPLQIQELQYMLEDFSPELIHEALKEAVSQGKANFAYIKVILN
                     RWKQDNLLTVELVRNSRAAREAKKQQTNQLEPTSYEDWIPTQEKPF"
     gene            complement(6384..6836)
                     /locus_tag="VU534_001523"
     CDS             complement(6384..6836)
                     /locus_tag="VU534_001523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000141102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1514095.1"
                     /translation="MTETTYENLTRRIDRISAEMREISEENGLRILSLLESQTKSIKD
                     ELSRLLWIELPELNESHKIEAVSKSTTGMFFAPGIFEMDAMRKAFFKRQAKHFFENEA
                     EQQAYIEHAEKEYLEATVTLKDILFNSKNGTQKANKSCLIEKFEEAMQ"
     gene            complement(6871..7488)
                     /locus_tag="VU534_001524"
     CDS             complement(6871..7488)
                     /locus_tag="VU534_001524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rha family transcriptional regulator"
                     /protein_id="HEU1514096.1"
                     /translation="MELVYMDGKKEPYTTSEIIAECAEVQHHTITRLIRENKADFEEL
                     GILGFKIHKLDTRGQPKKSYILNEQQATFLITYLKNTETVRQFKLNLVKAFFEMREEL
                     SEIRLQRALEKPKRKTLHDSIETWPNAPKHAHSTMNNLLLKAVTDMNAKQLREERGGY
                     NGIDSLTSEELEQYQAFEDMAIAMIELKMSYQEIKTMMFRSKKIS"
     gene            complement(7693..7845)
                     /locus_tag="VU534_001525"
     CDS             complement(7693..7845)
                     /locus_tag="VU534_001525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1514097.1"
                     /translation="MKIVTFKPTKQIDDGFYLPGIDILFVSDKADAKDKEDVILFLSR
                     NGLNKS"
     gene            complement(7856..8122)
                     /locus_tag="VU534_001526"
     CDS             complement(7856..8122)
                     /locus_tag="VU534_001526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015604664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1514098.1"
                     /translation="MEILSKEIQLQGLQLLKQTLETLVELEKQRSSKLDLISRKELMD
                     LLGISATTLDNWEDLGLKRYQTPMDGAKKVFYRPSDVYLFLAIK"
     gene            complement(8222..8575)
                     /locus_tag="VU534_001527"
     CDS             complement(8222..8575)
                     /locus_tag="VU534_001527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU1514099.1"
                     /translation="MSKENKMRGYRNMLGLTQEKLGKKLGISKQSYYNKESGKTQFSD
                     KEKLKIKNLLIPLFPDITIEDIFFKQKYAKVKSAKNGIKAKIKAVYRRPNQRTRLRKN
                     NKTQAKARRVVLLGI"
     gene            8695..9543
                     /locus_tag="VU534_001528"
     CDS             8695..9543
                     /locus_tag="VU534_001528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU1514100.1"
                     /translation="MKINNKLVGERIQNIRLSHGDSMEKFGEKFNTSKGTVNNWEKGR
                     NLPNKENLLKIASIGKMSVEELLYGDYNTYLHLKIMDLAPECIKNYDEYNSLHDDITN
                     KALQIAQNTISKIDYQISDETIKKFIDLAIEQSRDLQGNLLKNNLSNFDYSLFGGTRN
                     REYFYFGYRLTYKEKYLYTALLAILNESTKTIYIDDINTARFFNFFGNDIPNSSLKKI
                     DYIAPSEIVSFSTYVRQRSKVIPKILEHILKSSFLLENIDVSGYTVNILEDQLTKHRT
                     IKISKN"
     gene            9618..10781
                     /locus_tag="VU534_001529"
     CDS             9618..10781
                     /locus_tag="VU534_001529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015604661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEU1514101.1"
                     /translation="MNIKEKIKKNGQRVYYASVYLGVDQLTGKKARTTVTATTKKGVK
                     VKARDAINTFAANGYTVKDKPTITTYNELVKVWWDSYKNTVKPNTRQSMEGLVRVHLL
                     PVFGDYKLSKLTTPILQQQVNKWADKANKGEKGAFANYSLLHNMNKRILKYGVAIQVI
                     QYNPANDVIVPRKQQKEKAAVKYLDNKELKQFLDYLDALDQSNYENLFDVVLYKTLLA
                     TGCRISEALALEWSDIDLESGVISINKTLNRYQEINSPKSSAGYRDIPIDKATLLLLK
                     QYKNRQQIQSWKLGRSETVVFSVFTEKYAYACNLRKRLNKHFDAAGVTNVSFHGFRHT
                     HTTMMLYAQVSPKDVQYRLGHSNLMITENTYWHTNQENAKKAVSNYETAINNL"
     gene            complement(10935..12239)
                     /gene="eno"
                     /locus_tag="VU534_001530"
     CDS             complement(10935..12239)
                     /gene="eno"
                     /locus_tag="VU534_001530"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HEU1514102.1"
                     /translation="MSIITDVYAREVLDSRGNPTLEVEVYTESGAFGRGMVPSGASTG
                     EHEAVELRDGDKSRYGGLGTQKAVDNVNNIIAEAIIGYDVRDQQAIDRAMIALDGTPN
                     KGKLGANAILGVSIAVARAAADYLEIPLYSYLGGFNTKVLPTPMMNIINGGSHSDAPI
                     AFQEFMILPVGAPTFKEALRYGAEIFHALKKILKSRGLETAVGDEGGFAPRFEGTEDG
                     VETILAAIEAAGYVPGKDVFIGFDCASSEFYDKERKVYDYTKFEGEGAAVRTSAEQID
                     YLEELVNKYPIITIEDGMDENDWDGWKALTERLGKKVQLVGDDFFVTNTDYLARGIQE
                     GAANSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTIADIAVATNAGQ
                     IKTGSLSRTDRIAKYNQLLRIEDQLGEVAEYRGLKSFYNLKK"
     gene            12403..12849
                     /locus_tag="VU534_001531"
     CDS             12403..12849
                     /locus_tag="VU534_001531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000131081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YueI family protein"
                     /protein_id="HEU1514103.1"
                     /translation="MTDLSKQLLEKAHGGLKINPDEQRRYLGTFEERVLGYVDIDTAN
                     SPQLEKGFLFILENLQEKAEPLFVKISPTIEFDKQVFYLKEAKETDSQATIVSEEHIT
                     SPFGLVIHSNAPVQVEEKDLRLAFPKLWEVKKEEPAKTSLWKKWFS"
     gene            complement(12846..13961)
                     /locus_tag="VU534_001532"
     CDS             complement(12846..13961)
                     /locus_tag="VU534_001532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HEU1514104.1"
                     /translation="MKIVIAPDSFKESLTAQQVAEAIKRGFQQSIADVECLLCPVGDG
                     GEGTVDAIRHSLDLKEKWIQVTDPFGQKEAMRYFQKGELALFEVADLVGLGKIPLEKR
                     NPLQIQTCGIGELILHLISKGIKDIYIGVGGTASNDGGLGIAAGLGYQFYDRDGNVLP
                     ASGQSLLNLASVSTENCYKIPEGVQIHILADVVSPLCGHQGATYTFGNQKGLHPTMFA
                     VVDQAIQDFYEKFSPATLEIKGAGAGGGLAGGLCAFAQASIVSGIDTCLDLINFDKKV
                     SDADLVVVGEGRLDSQSFAGKAPIGVAKRTPVGVPVIAICGSLAEDLPPLPFENIQAV
                     FSILEKSEPLEDSLKNASFYLERTAANIGHLLNMCKI"
     gene            complement(13970..14203)
                     /locus_tag="VU534_001533"
     CDS             complement(13970..14203)
                     /locus_tag="VU534_001533"
                     /inference="COORDINATES: protein motif:HMM:NF019887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD hydrolase family protein"
                     /protein_id="HEU1514105.1"
                     /translation="MISPQVKKETLEKWRKKLKLSKERTVAIGDGVNNLLMLKSAKLG
                     IAFCAKEVLKKEIPHHVDKRDFLEVLPLIDCLE"
     gene            complement(14244..14615)
                     /locus_tag="VU534_001534"
     CDS             complement(14244..14615)
                     /locus_tag="VU534_001534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IB family phosphatase"
                     /protein_id="HEU1514106.1"
                     /translation="MSQVKGLCVLDVDGTLILEEVIDLLGREAGHEAEISQITSRAMR
                     GELVFESSLRKRVSLLEGLPILVFDNVFNSIHLSLNVPEFISILQKNGILVGLVSGGF
                     TPIVGEISKIPWYCLFHCQLA"
     gene            complement(14674..16107)
                     /gene="glgA"
                     /locus_tag="VU534_001535"
     CDS             complement(14674..16107)
                     /gene="glgA"
                     /locus_tag="VU534_001535"
                     /EC_number="2.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen synthase GlgA"
                     /protein_id="HEU1514107.1"
                     /translation="MKILFVAAEGAPFSKTGGLGDVIGALPKSLVKAGHEVAVILPYY
                     DMVEAKFGNQIEDVLHFEVSVGWRRQYCGIKKTVLNGVTFYFIDNQYYFFRGHVYGDF
                     DDGERFAFFQLAAIEAMERIDFIPDLLHVHDYHTAMIPFLLKEKYRWIQAYEDIETVL
                     TIHNLEFQGQFSEGMLGDLFGVGFERYADGTLRWNNCLNWMKAGILYANRVSTVSPSY
                     AHEIMTSQFGCNLDQILKMESGKVSGIVNGIDADLYNPQTDALLDYHFNQEDLSGKAK
                     NKAKLQERVGLPVRADVPLVGIVSRLTRQKGFDVVVESLHHILQEDVQIVLLGTGDPA
                     FEGAFSWFAQIYPDKLSTNITFDVKLAQEIYAACDLFLMPSRFEPCGLSQMMAMRYGT
                     LPLVHEVGGLRDTVRAFNPIEGSGTGFSFDNLSPYWLNWTFQTALDLYRNHPDIWRNL
                     QKQAMESDFSWDTACKSYLDLYHSLVN"
     gene            complement(16104..17243)
                     /gene="glgD"
                     /locus_tag="VU534_001536"
     CDS             complement(16104..17243)
                     /gene="glgD"
                     /locus_tag="VU534_001536"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase subunit
                     GlgD"
                     /protein_id="HEU1514108.1"
                     /translation="MKIDKYSAILGNTVGFHNMSTLTDHRPVASLPFGGKYRLIDFPL
                     SSLANAGVRSVFGIFQQDNISSVFDHIRSGREWGLSTLLSHYYLGIYNTRVESSTVGK
                     EYYQQLLTYLKRSGSNQTVALNCDVLINIDLNQVFHLHSTTKEPITVVYKKLAKKDIS
                     EVNAILDVDETDHVLSHKLFDSKSTAETFNMSTDIFVVDTPWLIEHLEEEAKKEHPEK
                     LRYVLRDLAVKEGAFAYEYTGYLANIHSVKSYYQANIDMLESQKFYSLFSPNQKIYTK
                     VKNEEPTYYANTSKVSTSQFASGSIIEGQVANSVLSRNIHVHKDSLVKDSLLFPRVVI
                     GEGAQVEYAILDKGVEVEHGVVIRGTAEHPVVVKKGAKVTEDIHS"
     gene            complement(17233..18375)
                     /locus_tag="VU534_001537"
     CDS             complement(17233..18375)
                     /locus_tag="VU534_001537"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000787267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase"
                     /protein_id="HEU1514109.1"
                     /translation="MKNEMLALILAGGQGTRLGKLTQSIAKPAVQFGGRYRIIDFALS
                     NCANSGIHNVGVVTQYQPLALNNHIGNGSSWGLDGINSGVSILQPYSASEGNRWFEGT
                     SHAIYQNIDYIDSVNPEYVLILSGDHIYKMDYDDMLQSHKDNNASLTVAVLDVPLKEA
                     SRFGIMNTDANNRIVEFEEKPAQPKSTKASMGIYIFDWQRLRNMLVAAEKSKVGMSDF
                     GKNVIPNYLESGESVYAYEFSGYWKDVGTIESLWEANMEYISPENALDSRNRQWKIYS
                     RNLISPPNFLGANAHVEDSLVVDGCFVDGTVKHSILSTGAQVREGAEVLDSVIMSGAI
                     IGQGAKIKRAIIGEGAIISDGVEIDGTDEVQVVGYNEVVGVATDED"
     gene            complement(18365..20293)
                     /gene="glgB"
                     /locus_tag="VU534_001538"
     CDS             complement(18365..20293)
                     /gene="glgB"
                     /locus_tag="VU534_001538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-alpha-glucan branching protein GlgB"
                     /protein_id="HEU1514110.1"
                     /translation="MDNREALKTFMTGENFYLQHYLGAHREELNGEHGYTFRVWAPNA
                     QAVHLVGDFTNWIENQIPMVRNDFGVWEVFTNMAQEGHIYKYHVTRQNGHQLMKIDPF
                     AVRYEARPGTGAIVTELPEKKWKDGLWLARRKRWGFEERPVNIYEVHAGSWKRNSDGS
                     PYSFAQLKDELIPYLVEMNYTHIEFMPLMSHPLGLSWGYQLMGYFALEHAYGRPEEFQ
                     DFVEECHTHNIGVIVDWVPGHFTINDDALAYYDGTPTFEYQDHNKAHNHGWGALNFDL
                     GKNEVQSFLISCIKHWIDVYHLDGIRVDAVSNMLYLDYDDAPWTPNKDGGNLNYEGYY
                     FLQRLNEVIKLEYPDVMMIAEESSSAIKITGMKEIGGLGFDYKWNMGWMNDILRFYEE
                     DPIYRKYDFNLVTFSFMYVFKENYLLPFSHDEVVHGKKSMMHKMWGDRYNQFAGLRNL
                     YTYQICHPGKKLLFMGSEYGQFLEWKSEEQLEWSNLEDPMNAKMKYFASQLNQFYKDH
                     RCLWEIDTSYDGIEIIDADNRDQSVLSFIRKGKKGEMLVCIFNMVPVERKDFTIGLPV
                     AGIYEEVWNTELEEWGGVWKEHNQTVQTQEGLWKDYEQTLTFTLPAMGASVWKIKRRL
                     KSTKTVTNKNQKGVENEK"
BASE COUNT         6188 a         4287 c         3294 g         6807 t
ORIGIN      
        1 ttttgtcttg ttcttgtttc aattgactat ataaattgtc taagcgaaac aaccgataag
       61 aattggcaca aaagcgaccg tatttttgtt accaatacag gaaaaacagt tcatagttct
      121 atcttgagca agtctctcca gcgagcaaac gaacgcctta aaaaaccaat tcccaaacat
      181 ctgtcccctc acatcttcag acacaccact attagcatct tatcagaaaa taaaattcct
      241 ttaaaaacaa tcacggacag ggttggtcat cccgactctg aagtcactac ttccatctac
      301 acccacgtca caaagaacat gaaagatgaa gcaatcaatg tactggataa agttatgaaa
      361 aagatttttt aaaaagtttt gtcccttttt tgccctctaa atacaaaaat agcccttcgg
      421 ataaaatccg aggggctaga aacgttgtta aatcaacggc cgaacttttg aatttcatgg
      481 ttcgggataa aatagttcac tgaactattt tattttttaa ggttatcata atatcaaata
      541 gttcaattaa atacgctaaa ttactaatat actttttacc tttttcattc taaaatgtaa
      601 agtacaaaca attacaatat actagagggg gagtaaaaaa ggtattaaat cgatgagttc
      661 agcaggcaag aaaatagcac ctttacgggt gctatttttt aattaacgcc acgttaactt
      721 ttgattgatg aattttattg tttggcactt ctttcatttc acggtaaaca tcgatgaaat
      781 tctttccaac attatttttg gagttaactg catttatttt tgtattaata acttttttag
      841 tatcgaaaga atggtttaag aaatccataa ctaactctcc tttctcatcc tgtaatcaag
      901 atttttatca atgtcaaaat agtattttct atcaatccaa attggtcctt ctcctttaga
      961 aatagcaagt acatctaccg gacctcctac tgtttcaaga gtgttgacaa tttttctctt
     1021 aaatgaagtt aattcaataa atgttttagc tgtactcgcc atttcattaa gtggttgcat
     1081 tccaataagg tctattatag gatttatata atatttttgc tgtatagatg atatattttc
     1141 aaatatattc tcaatttcat cacccaatcc atttttctcc ataactgatg atacttgctc
     1201 tgcgatatat acatttaagt taggatctat accattcata atcgtctcaa ccatctctga
     1261 ctgtgcaaaa gggattatat gacaagtttt atgatgattt atcacacttt cattaataac
     1321 tttccaaatt aatcgtttag aaaaaattcc atataattca atttgtctta tagatggaaa
     1381 tatctcgtct gtaccataac ctgctataac taatccagtt atgtttgttg agtcatatcc
     1441 aatgaaaatc gctttatata aagatttagc aataacttca acctcatcat cagtatgagg
     1501 aaaggattta aaaacatcgt ctacaatgct ttttattaac tctaactcag cttcaaaaaa
     1561 ttcaaaatta ctttcagctt ctacttttga aatttctaaa ctaaaattag ttatagcatt
     1621 taataaaatt ttattaaaat catctagagt gatggtttca ccattagaaa ctcttaaatc
     1681 agctgtttct tgcgcttcat aggcaatgct gtccaaaata cttcttgtac ttctgacaat
     1741 ataatttctt aataaatcct caacttgtag atgtttaaag gaaattaaaa attctattag
     1801 cttttcaacg tattgggcag tattatctaa taaatctgtg ccaatagcct gcttaaactc
     1861 atttaaaatt acctcccacg gaatttccat aaacgaagcg ttcccatata tcatgatccc
     1921 cacggaatgt tcttttgata aagtgaataa ttttcgggcg ctattaaaaa cttttgaatt
     1981 tttcccgtct gataaggtta cagcgctatc agaagccaat acaacaccat ttttatttaa
     2041 tattccaatt tctgctgtca aaatatcacc taaactttct aaacctgctc atgctctaat
     2101 ggtacaacag ctaaggtctt accaagactt gccaacactt ttaatactgt atcaagttgt
     2161 gggcttgtct ttcctgtttc cattctagcg ataactggct gactaacacc gctcatctcc
     2221 tctagtttct tctgactaat acccttttca tttctagcct cgataagctc actcatgata
     2281 gccacgcgca tatcactttc caaaatttcc tctttgctga ataattcagc tcttacatct
     2341 ttccagttac taccaatagc attatttttc attgtctaaa cctctttctt ttaaatctgc
     2401 aagttcacgt ttagcttgct caatctctct tttgggtgtt ttctgtgtcc ttttcataaa
     2461 atgatgcagt aaaacaaaac taccatccat ccaagcaaca aataaaattc tatctctaag
     2521 tggtctcagc tcccaaattt cagcatctaa atgcttaata tatggttcgc ctgcgcgtgt
     2581 tccatgttgg cttaacaact caatataatc attaatttta ttaagcttaa ttctgctatc
     2641 tttccctttt ttactggtaa gctctcgcat ataatcaaaa acaggctcat tgccgttttt
     2701 atccttgtaa aaatagatat tatgcactat taacacctct tcctaataac aattataacc
     2761 taaaagttat tgtttgtaaa tacttttaag ttattaaaat aaaaagcacc tagtttccta
     2821 gatgctagca caatgacacg gattcgcacc gtggctacct ctatcaaggt gtactccttc
     2881 tatactatcc cttgtgcttt agaatattat accacacaat caactagata cctaccatct
     2941 catgatatac ccccattttg ggcaagggta caacgctaaa atacaaatca gaatagatat
     3001 taaaccactt atttaactta tcataagctg gtgattgact gataaataat atccgctgac
     3061 aagctccgat aacattcatg tgattgtaca cataaacctc ttttacagcc tctaaaatgt
     3121 cagcctcact tgtttgtacc ctaatatctg ttatctgctt gatagttgcg tatttttgat
     3181 aagctagcat atcttgattt ttagcagcat caaacatttt acgctcaagg acactatact
     3241 taggttgttc tttatctcgc atgaaatacc acttgagcca taaaatcttt tctcggtgta
     3301 ttacagaaat acgctcaatt ttcttctttg tcattgctac ctcctaaatc atcaatttaa
     3361 caattctaac cactcacttt tagaaatagt tgcatagatc ttgttcgatg tatgatacaa
     3421 aggttctaaa tctttttcca ccctaatata gttcatctta tcctcatgag taggaaagta
     3481 tagtatttcc gtttcatcct cgtttaggat acgattgcac caatcatcaa taataactgg
     3541 cacttcccac tcacgccatt ttttaaggtt ttctaaaagt tcattatcac taaatagctc
     3601 gccatctatt tggaaaaatt cccctaagtc attgtttcct tcaacaataa taaactctgg
     3661 catatttcta ttacttaata actccttgag ttcttgtaac tctttgattt cctttagata
     3721 cttcctcaat ttccaacctc aattcttcaa tctgccttac tactccaaaa atttcatggg
     3781 tcttataaga ttgttcaagt atagcctttg ctgcttgagt tcttataaac gggttgacct
     3841 tactgtccat cataatatca ttgagtacag aaacagcgtt agatgatgct aaataaagca
     3901 tttgagttgt tttatccatc atctcatctt gctttatcct caatgtcttt ttaaccgctg
     3961 caacttttag atacttatga cctgttgcgc gtgatacccc tgctttttga catgctttgt
     4021 ctatcgttgg ctcggtaagc atggcatcta tgaatttaat ttgcttggac gtaaggttat
     4081 cattttcatt tcctgccatc tattacctcc tcattatcaa aataaagggt tgccccttta
     4141 tttccctatg ctagataatt ctgcaattct gcatccattg cctctgaatt gccctcaaca
     4201 atcatttcat gctgtactaa atcaatctta tctccgttaa taagtaaacc accgtggaaa
     4261 taatcaattt ttctatcaag gaaatgtact agcttttcaa ggcgttgctg ttggctgaat
     4321 tgctccatgt caatttcgat ataagcaagg gtagtatcat tatccataat atcttctaat
     4381 tttctaagag ctagaggttt atttttatat ttttctaggt attctctcat ttctgccact
     4441 gttaatttga tactagataa taaacttagt tcagctgcat catctgctgt aataggctct
     4501 tcttttgatt catggtttgc tagttcagca tttttctctt tttctagttg ctgatacaat
     4561 agctgagcag tattttggga atagttttcg ccctcttttt tatattttaa aagttcttgc
     4621 tctgcataca ctttcccgat aatcacttcc ttataaacta attgcccatc ttgagctttt
     4681 agcttaatac tcccatgctc tggaatttca atatacttaa ttataccatt ttttgagtat
     4741 aaaacaaagc ctttctccat catttttaat aatttatcat ccttgttttc agtcatgctt
     4801 ttctccttta tttcatttta ttataatctg aataccccta gtctatttat ttcactaggt
     4861 ttttagggtt cgtatgctaa aatactaccc tttttgtgta ccttatggct gacttttcaa
     4921 attggttagt ttgccacact tggtttatat ggtcgtggaa agcatggcta ttacttctca
     4981 aagggcgatt tctcacccca tgaaaagtgt ctatttttgt ttaggtttgt aagttaattc
     5041 attgtcacat attactcttt aactgattga gtgagtaccg cttatatttg atgccaaacg
     5101 ccttaaaagt gttaccctca agtcctttta gaatacggct ataattccgc tcattgtaaa
     5161 ctatcttaag ctcatcacta tctaggttgg tattaaaaat ggtattttca cgattgttta
     5221 gcacgtcaaa gagtaaatcc tgctcccagt cactcttagg cttaataaca gcattttttg
     5281 ctcctaaatc atcaataatt aagtaatcaa cagacttcat gagttcagta gcttcaaact
     5341 ctgtaagtgt tgcaccttta ccataattcc acccctcttt aatttgtttg atcatttcgg
     5401 ttaggcttac aaaaagcaca ctcttaggtt ctccttttgt cttatacccc tcatttatac
     5461 ctttggcaat agcaactgat aaaagtgttt ttccaatccc tgtacctcct gtgataagcg
     5521 tatttcccct catgccatca agatattttt gtacctgacc ttttgcaaat tctaaaaatc
     5581 gcttttcttc tgatgttaca gcattaaaat catcaaaagt tttagtttta aactcatctg
     5641 ctacatagct cttattgctc atcaacacat tataagtttg catatatagt ttagcattca
     5701 aattatcagc aatcgcatct tcttcatctt gctttttctg ttcttcttgg cattgttcac
     5761 aatagggtgg gatacagcga acttctttta ttgcctctcc gttctcattc caccccacta
     5821 ctacatgtct ttctcctttg atttgtgtta gctgtatttc atgcttagga cacaattcgt
     5881 ctagtttaaa tgtctcaata tttcctaaac tagattgtaa tgatttcatt ttctgacctc
     5941 ctaaaatggt ttttcttgtg ttggtatcca atcttcatag ctggtaggct ctagttgatt
     6001 ggtttgctgt tttttagcct cacgcgctgc cctgctattt ctaacaagtt ccaccgtcaa
     6061 taaattgtcc tgtttccaac ggttaaggat taccttgatg tatgcaaagt ttgctttacc
     6121 ctgactgaca gcctctttta acgcctcatg gataagctct gggctaaaat cttctagcat
     6181 atactgcaat tcttgaatct gtaacggtga caatgcttta cctgtctcag ctcgcttcat
     6241 attcaacaag tcgtctattt ccacactggt tactttttta tttacaaaat cagaaatcag
     6301 ttgaaaaatg tttggacttt gtagctggat ttcagccatt acctcatcaa attctgcttg
     6361 tgtcatgttg tctaaatcta gtgtcattgc attgcctcct caaacttctc tataagacaa
     6421 cttttatttg ctttctgagt tccattttta gagttaaaaa gaatatcttt taaggttaca
     6481 gtagcctcta aatactcctt ttcagcatgc tctatatacg cctgttgctc tgcttcgttc
     6541 tcaaaaaagt gcttagcttg gcgtttaaag aatgcttttc gcatagcgtc catttcaaaa
     6601 ataccagggg cgaaaaacat tcccgtagtg cttttagaga ccgcttcgat tttatggctt
     6661 tcattcaatt caggaagttc aatccaaagt aaacgggaca actcatcttt gatggatttt
     6721 gtctgacttt ccaataaaga aaggattctt aggccatttt cttcgctaat ttctcgcatt
     6781 tctgcgctaa ttctgtctat acgtctagtt aaattctcat atgttgtttc tgtcatgttt
     6841 ttacctctgt ttctttgttg gtgtgatttt ttagcttatt tttttacttc taaacatcat
     6901 tgtcttaatt tcctgataac tcattttcaa ttcaatcata gctattgcca tatcctcaaa
     6961 tgcctggtac tgctccaact cctcactagt caagctatcg ataccgttat agcccccacg
     7021 ctcttctctt aactgcttag cgttcatgtc tgttactgcc tttagtagca agttgttcat
     7081 ggtgctatgc gcgtgctttg gtgcattagg ccatgtttct atactgtcat gcaaggtttt
     7141 tcttttcggt ttttctagcg ccctctgcag acgaatttca gaaagttcct cacgcatttc
     7201 aaagaatgct ttgactaggt ttagtttgaa ttgccgtact gtttcggtat tctttaaata
     7261 agtgatcaga aaagtagcct gttgctcgtt cagaatatag gattttttag gttgtcctct
     7321 agtatctaat ttatggattt taaatccaag tattcccaac tcttcaaagt cagccttatt
     7381 ttctcttatt aagcgcgtga tagtgtggtg ttgtacttca gcacattcag cgatgatctc
     7441 gcttgtggtg tacggctctt tcttaccgtc catgtaaact agttccatta cggttctacc
     7501 tcctgtataa atctggttag cttacttttt aattgcctcc tctagcctct tttttagcct
     7561 ctaaaacggc tttggctagt ggttaatatt atttaccact tgtctctata aacgtgttag
     7621 aggcctttat aacgacttgt atcgctgtat cgatatcctc cgtggaatag tagatttatt
     7681 ttctaatatc attcaagact tgtttaaccc atttcttgaa agaaataaaa ttacatcttc
     7741 tttatccttg gcatctgctt tgtctgagac aaatagaatg tcaatacctg gcagataaaa
     7801 cccatcgtct atttgtttag ttggtttgaa agtaacaatt ttcatttcat aactcctatt
     7861 ttattgctaa aaataaatac acatctgacg gacgatagaa tactttctta gctccatcca
     7921 tcggagtctg atatcgttta agaccaagat cctcccagtt atcaagggtt gtagcactta
     7981 tacctagcag atccattaat tctttacgag aaattaaatc taacttacta gatcgttgtt
     8041 tttctagctc aactaaagtt tcaagagtct gtttaagaag ttgtaagccc tgtaactgta
     8101 tttctttaga cagaatttcc atttatatcc tccatttttc ctttttataa attaagttgt
     8161 cattttcctc taattttgat aaaataagag gagattattt acaaaggggt ttgtcccctt
     8221 gctaaatacc taacaaaacc acgcgccttg cctttgcttg agttttgtta tttttcctta
     8281 gccgtgtacg ttggtttggt cgcctgtaca cggcttttat tttcgcttta attccatttt
     8341 ttgcactctt tacttttgca tacttctgtt taaaaaatat atcttctatt gtaatatctg
     8401 gaaataaagg gattaaaaga tttttaatct taagtttttc tttatctgaa aattgtgtct
     8461 tcccactttc tttgttgtaa taactctgct tagatatacc aagttttttt ccaagtttct
     8521 cttgtgttaa acctagcata ttcctatatc cacgcatctt gttttcttta ctcatttcta
     8581 tacctccttt acttttgcat acctagatta taaaacttta tttttataaa gtcaatactt
     8641 ttctttactt tttcttaaaa aaagtttatt atgttcttta aggaggtgta aaacatgaaa
     8701 ataaataata aactcgttgg agaacgtatt caaaatatcc gtttaagcca tggcgactct
     8761 atggaaaaat ttggagaaaa atttaatact agcaaaggta cagttaacaa ctgggaaaaa
     8821 ggtcgcaatt taccaaataa agaaaaccta ctaaaaattg catctattgg aaaaatgagt
     8881 gttgaagagt tactctacgg cgattacaat acttatctac acttaaagat tatggattta
     8941 gctcctgaat gtataaaaaa ttatgatgag tataactctt tacacgatga tataacaaat
     9001 aaagcgttac agatcgctca aaataccatt tctaagattg attatcaaat ttcagacgaa
     9061 acgatcaaaa aatttattga tttagctatc gaacaatcga gagatttgca aggaaatttg
     9121 ttgaaaaata acttatctaa ttttgactat tcactttttg gaggtactag aaaccgagaa
     9181 tatttctatt ttgggtatag acttacctat aaagaaaaat atctatacac tgccttacta
     9241 gctatactga acgagtcaac aaaaacgata tatattgatg atataaatac agcaagattt
     9301 tttaacttct ttggcaatga tattcctaat tcgtctttaa aaaaaattga ctatatcgca
     9361 ccttcagaaa ttgtttcatt tagtacgtac gttcgacaac gttctaaagt aattcctaaa
     9421 attttggaac atatattaaa atcaagtttt ttattagaga atatagatgt ttctggttac
     9481 actgtaaata ttttagaaga tcaattaaca aaacatagaa caatcaaaat tagtaaaaac
     9541 taactggttg atctcatgta taaataccta acaaaaccac gcgccttgcc tgctgatgga
     9601 aagaaaggta caaatacatg aatatcaaag aaaaaatcaa aaagaatggc caaagagttt
     9661 attatgctag tgtttatcta ggcgttgacc aactaacggg caaaaaagcc cgtacaactg
     9721 ttacagcaac cactaaaaag ggcgttaaag taaaagcgcg tgatgcgatc aatacttttg
     9781 ctgctaatgg ctatacagtt aaagacaagc cgacaattac aacatataat gagcttgtaa
     9841 aagtttggtg ggatagttac aagaatacag ttaagccaaa tactcgccaa tccatggagg
     9901 gattggttag agtgcattta ttgcctgtat ttggcgatta caagctatct aaacttacta
     9961 cgcctattct tcaacagcaa gtaaacaaat gggctgacaa ggcaaataaa ggcgaaaaag
    10021 gggcatttgc taactactct ttgctccata acatgaataa gcgtattttg aaatatggcg
    10081 tagctatcca ggtaatacaa tacaacccag ctaatgatgt catcgttcca cgcaaacagc
    10141 aaaaagaaaa ggctgctgtc aaatacttag acaacaaaga attaaaacag tttcttgatt
    10201 atttagatgc tctggatcaa tcaaattatg agaacttatt tgatgttgtt ctgtataaga
    10261 ctttattggc cactggttgc cgtattagtg aggctctggc tcttgaatgg tctgatattg
    10321 acctagaaag cggtgttatc agcatcaata agacactaaa ccgctatcag gaaataaact
    10381 cacctaaatc aagcgctggt tatcgtgata taccaataga caaagccaca ttacttttac
    10441 tgaaacaata caaaaaccgt caacaaattc agtcttggaa attaggccga tctgaaacag
    10501 ttgtattctc tgtatttacg gagaaatatg cttatgcttg taacttacgc aaacgcctaa
    10561 ataagcattt tgatgctgct ggagtaacta acgtatcatt tcatggtttc cgccatacac
    10621 atactactat gatgctctat gctcaggtta gcccgaaaga tgttcagtat agattaggcc
    10681 actctaattt aatgatcact gaaaatactt actggcatac taaccaagag aatgcaaaaa
    10741 aagccgtctc aaattatgaa acagctatca acaatttata aaaaataagg gtgacccatt
    10801 tccgggctac cctcttacta taccaaaaat tagtaggggt agtaaaaagg gtattaaatt
    10861 ataaaaagca ctaagggaaa gcgccccaaa gtgcttattt caaaggcttt atagcctata
    10921 atcacataaa gagattattt tttaaggttg tagaatgatt tcaatccacg atattcagct
    10981 acttcaccaa gttggtcttc gatacgaagc aattggttgt atttagcgat gcggtctgta
    11041 cgtgaaagtg aaccagtctt gatttgtcct gcgttagttg caactgcaat atcagcgatt
    11101 gttgaatctt cagtttcacc tgaacggtgt gatacaacag cagtgtaacc agcttcttta
    11161 gccatttcga tagcttcaaa agtttcagta agagtaccga tttggttaac tttgataagg
    11221 attgagttag cagcaccttc ttggatacca cgtgcaaggt agtcagtgtt tgttacgaag
    11281 aagtcgtcac caacaagttg tactttctta ccaagacgtt cagtaagagc tttccaacca
    11341 tcccagtcgt tttcatccat accatcttca atagtgatga ttgggtattt gttaaccaat
    11401 tcttcaaggt agtcgatttg ttctgcagat gtacgaacag cagcaccttc accttcaaat
    11461 ttagtgtagt cgtaaacttt acgttcttta tcgtagaatt ctgatgaagc acagtcaaat
    11521 ccgataaata cgtctttacc tggtacatat ccagcagctt caatcgcagc aaggatagtt
    11581 tcaacaccat cttcagttcc ttcgaaacga ggagcgaatc caccttcgtc acctacggca
    11641 gtttccaaac cacgtgattt aaggattttc ttaagagcgt ggaagatttc agcaccgtaa
    11701 cgaagggctt ctttaaatgt tggcgcacca actggcaaga tcatgaactc ttggaaagcg
    11761 attggagcgt cagagtgaga accaccgttg atgatgttca tcattggagt tggaagaact
    11821 ttagtgttga atccaccaag atagctgtaa agtgggattt caaggtagtc agcagcagca
    11881 cgagctacag cgatagacac accgaggatt gcattcgcac ccaatttacc tttgttagga
    11941 gtaccgtcaa gtgcgatcat agcacggtca atagcttgtt gatcacgtac atcgtagcca
    12001 atgatagctt cagcaatgat gttgtttacg ttgtcaacag ctttttgtgt accaagacca
    12061 ccgtaacgag atttgtcacc gtcgcgaagt tcaactgctt cgtgttcacc agtagaagct
    12121 cctgatggaa ccataccacg tccgaaagca cctgattcag tgtaaacttc tacttcaagt
    12181 gttgggttac cgcgtgagtc taggacttcg cgagcgtaaa catcagtaat aattgacatt
    12241 ttttactctc cttatgagtt aaatttttta cacctctata ataccttaaa acccctcctt
    12301 tttcaagaaa aaacgttatc tttgtgcaac ttttccttaa ctttataaag taatcgcttt
    12361 cttttgtctg ttttattcta acttttatga tatactgttt tcatgacaga tttatcaaaa
    12421 caattacttg aaaaagctca tggtgggtta aaaataaatc cggatgagca aagacgctat
    12481 cttggtactt ttgaggaaag agttcttgga tatgtagata ttgacacagc aaatagccct
    12541 cagttagaaa aaggcttttt atttatttta gaaaaccttc aggaaaaagc agagccacta
    12601 tttgtgaaga tttcaccaac tatcgaattt gataagcaag ttttctactt aaaagaagca
    12661 aaagaaactg atagtcaagc caccatagta tctgaagagc atattacttc tccttttggc
    12721 ctggttattc atagcaatgc accagttcaa gtagaagaaa aagaccttcg acttgctttt
    12781 ccaaaacttt gggaagttaa aaaggaagaa ccagccaaaa catccttatg gaagaaatgg
    12841 tttagctaaa tcttgcacat atttaataag tgcccaatat tggcagccgt gcgctccaga
    12901 tagaaactgg catttttcaa actatcttct aaaggttcac ttttctccaa aatagaaaag
    12961 acagcttgga tattttcaaa tggtagggga ggtaaatctt cagcaagact accgcaaata
    13021 gcaataacag gaactccaac aggggttctt tttgcaacac ctataggcgc tttcccagca
    13081 aagctttgac tatcaagtct tccttctcca acaacaacca agtcagcatc tgaaactttc
    13141 ttatcaaagt tgattaagtc caagcaggta tcaattccag acacgatact tgcctgagca
    13201 aaggcacaca aaccaccagc aaggcctcca cctgctcctg ctcctttaat ttctaatgtt
    13261 gcaggtgaga atttttcata aaaatcttgg atcgcctgat ctacgactgc aaacatagtc
    13321 ggatgtagac ctttttgatt gccaaaagtg taagtcgcac cttgatgacc acataaggga
    13381 ctcacgacat ctgctaaaat atgaatttga acaccttcag gaattttata gcaattttct
    13441 gttgaaacag aagctaagtt taataaggat tgaccggaag caggcaagac atttccatcc
    13501 ctatcataaa attgataacc taaaccagca gcaatcccca gtcctccatc attactggcc
    13561 gtgccaccaa caccgatata aatatcttta atccctttag agatgagatg aagaatcaac
    13621 tctccaatac cacaagtttg gatttgaagt ggatttcgtt tctctagcgg aatttttcca
    13681 agaccaacca agtcagctac ttcaaatagt gccagttccc ctttttgaaa atagcgcatg
    13741 gcttcttttt gtccaaaagg gtctgtcact tggatccatt tttcttttag gtcaagagaa
    13801 tgtcggatag catctacagt accttctccc ccatcaccaa cagggcagag gagacattct
    13861 acatctgcta tcgattgttg gaagcctctt tttattgctt cagctacctg ttgagctgtc
    13921 aagctttcct taaacgaatc cggtgcaatt acaatcttca tattttccct cattctaaac
    13981 agtcaatcaa agggagaact tctaaaaaat ccctcttgtc aacatgatgt ggtatttctt
    14041 ttttgagcac ttctttggca caaaaggcga ttcctaactt cgccgacttc aacattaata
    14101 gattattaac cccatcaccg attgccaccg ttctttcttt agaaagtttt agtttctttc
    14161 tccatttttc cagagtctct tttttgacct ggggacttat aatttgtcca actaattttc
    14221 ctgttaaaag accttctttg acttcaagct agttggcagt gaaataggca ataccaaggg
    14281 attttgctaa tctctccaac tattggtgta aatccaccag acaccagacc aactaggatg
    14341 ccattctttt ggagaataga gatgaactct gggacattta gcgatagatg aattgagttg
    14401 aagacgttat caaagaccaa aataggaaga ccttccaaca aggacactct ttttcttaaa
    14461 ctgctttcaa agaccaactc tcctcgcatt gctcgacttg taatctgcga aatttccgcc
    14521 tcatgacctg cctctctccc taaaagatca atcacttctt ctaggattaa ggttccatct
    14581 acatccaaaa cacacaagcc ttttacttga gacatcagtt ctcctctcta aacagcctaa
    14641 aaatcgtatg aagtcatcat acgattttat ctattaatta actaaactat ggtacaagtc
    14701 aaggtatgac ttgcaggctg tatcccatga gaagtcactc tccatagctt gtttttgtag
    14761 gtttctccaa atgtctggat ggtttctata caagtccaat gctgtttgga aagtccaatt
    14821 taaccaataa ggagatagat tgtcaaagct aaagccagta ccgcttcctt cgattggatt
    14881 gaaagcgcga actgtatctc gcaagcctcc aacttcatgg accaatggca aggttccata
    14941 acgcatagcc atcatttgag acaagccaca cggttcaaaa cgacttggca tgaggaagag
    15001 gtcacaagca gcgtagattt cctgagcaag tttgacatca aaagtgatat ttgttgatag
    15061 cttgtctggg taaatctgag caaaccatga gaaagctcct tcaaaggctg gatcgccagt
    15121 tcccaaaaga acaatctgaa catcttcttg caagatatgg tgaagacttt cgaccaccac
    15181 atcaaaacct ttttgacgtg tcaaacgaga aacaattccc accagtggaa cgtctgctct
    15241 aacaggcaag ccaactcttt cttgcaattt tgccttattt ttggctttcc cagacaaatc
    15301 ttcctgattg aaatgatagt ctaaaagagc atccgtctga ggattataaa gatcagcatc
    15361 aatcccattc acgataccag atactttacc agactccatt ttaagaatct gatccaaatt
    15421 acatccaaac tgactagtca taatttcatg agcatagcta ggtgaaacgg ttgaaacacg
    15481 gttcgcatag agaatacctg ccttcatcca gttcagacag ttgttccatc gaagggtgcc
    15541 atcagcgtaa cgttcaaagc caactccaaa caaatcaccc aacattcctt ctgaaaattg
    15601 tccttggaat tctaaattat gaatggttaa aactgtttca atgtcctcat aggcttgaat
    15661 ccaacggtat ttttccttca acaagaaagg aatcatagct gtatggtagt catgaacatg
    15721 gagaagatca ggaataaagt caatcctttc catagcctca atggcagcca gttggaaaaa
    15781 ggcaaagcgt tctccgtcat caaaatcacc gtaaacatga ccacggaaga aataatattg
    15841 attgtcaata aagtagaagg ttacaccatt taatactgtt ttcttaattc cacaatactg
    15901 tctgcgccaa ccaacgctca cctcaaaatg aagcacatct tcaatctgat ttccaaattt
    15961 agcctctacc atatcatagt agggtaaaat cactgcaact tcgtgcccag cttttaccag
    16021 tgattttgga agagcgccaa tgacgtctcc caaaccacct gtttttgaaa agggtgcacc
    16081 ctctgctgct acaaataaaa ttttcatgaa tgaatatcct ctgttacttt agcacctttc
    16141 ttaaccacaa ctggatgttc tgcagttcct cgaatcacaa caccatgctc aacttcaacc
    16201 cctttgtcca agatagcata ttcgacctga gccccttctc caataacaac acgagggaag
    16261 agcaggctat ctttaaccaa gctatcctta tggacatgaa tattacgtga tagaacagaa
    16321 ttagctactt gaccttcaat aatactacca gaggcaaact gagaagtgct taccttagat
    16381 gtattagcat agtaagttgg ctcttcgttt ttgacctttg tataaatctt ttggtttggt
    16441 gagaaaagag aatagaattt ttgtgattca agcatatcga tattcgcttg ataataagat
    16501 ttaacagagt gaatattggc tagatagccc gtgtactcgt aggcgaaagc tccctctttt
    16561 acagccaaat cccgtaaaac atagcgcaat ttctctggat gttctttttt agcttcttct
    16621 tccaagtgtt caatcaacca aggtgtatca acgacaaaga tatctgtaga catattgaac
    16681 gtttcagctg ttgacttgct atcaaagagt ttatgagaaa gaacatggtc tgtttcatct
    16741 acatccaaga ttgcatttac ttctgaaata tctttcttag ctagtttttt ataaactaca
    16801 gtgataggct cttttgttgt actatgtagg tggaaaactt ggttcaaatc aatgttaata
    16861 agaacatcgc agttgagggc aaccgtttgg tttgagccag aacgtttcaa ataagtaaga
    16921 agctgttggt agtattcttt tccaactgta ctactttcta cacgggtatt gtaaattcct
    16981 agatagtaat ggctaagaag ggttgataag ccccactcgc gtcctgaacg aatatggtca
    17041 aatactgagc tgatattatc ctgctggaaa ataccaaaga cactacgaac acctgcatta
    17101 gcaaggcttg aaagtgggaa gtcaatcaaa cgatatttcc caccaaatgg caaacttgct
    17161 actggacggt ggtccgtcaa tgtcgacata ttgtgaaaac caactgtatt tcctaaaatg
    17221 gcagaatatt tatcaatctt catctgttgc tacccccact acttcattat atcctacaac
    17281 ttgtacttca tctgttccat caatttcgac accgtcagaa ataatcgcac cttcaccaat
    17341 aatggcacgt ttaatcttag ctccttgacc aatgatagct ccactcatga taactgaatc
    17401 aaggacttcc gctccttcgc gaacttgcgc gcctgttgaa aggatagaat gtttaacagt
    17461 tccatcaacg aaacatccgt ctacaactaa tgagtcttcc acatgagcat ttgccccgag
    17521 gaagtttggt ggtgaaatca agtttcttga gtaaatcttc cattgacggt tacgactatc
    17581 caaggcattt tctggagaaa tatactccat gttcgcttcc caaagtgact caatagtacc
    17641 aacatctttc caataaccac taaattcgta agcataaaca ctttcacctg actcaaggta
    17701 atttggaatg acatttttac caaagtctga catgccaacc ttgctctttt cagcagcgac
    17761 taacatatta cgaaggcgtt gccaatcaaa aatgtagatt cccatagaag cttttgtaga
    17821 tttaggttga gctggttttt cttcaaattc aacaatacga ttgttagcat ctgtgttcat
    17881 gataccaaaa cggcttgctt ctttaagagg gacgtctaaa actgctactg tcaagctggc
    17941 attattatcc ttatgagact ggagcatatc atcatagtcc attttgtaga tgtgatcccc
    18001 agacaaaatc aagacatact caggattgac actgtcgata tagtcgatat tttggtaaat
    18061 agcgtgacta gtcccctcaa accaacgatt tccttcactt gcagaataag gttgaagaat
    18121 agagacacct gaattaatac cgtctagtcc ccagcttgaa ccattcccaa tatggttgtt
    18181 gagagcaagt ggttgatact gtgtaacgac cccaacattg tgaatccctg agttggcaca
    18241 gtttgatagg gcaaagtcaa tgatacggta gcgcccacca aattgcacag ctggttttgc
    18301 gatgctttga gtgagtttac cgagacgagt tccttgccca ccagcaagaa tcaaagctaa
    18361 catttcattt ttcattttct actccttttt ggtttttatt tgtgacggtt ttagtagatt
    18421 tcaagcgacg tttgattttc catacacttg ctcccatagc cggtagggta aaggttaagg
    18481 tctgctcata atctttccat agtccttctt gcgtttgaac agtttgatta tgttctttcc
    18541 aaacgcctcc ccactcttcc aactcagtat tccatacttc ttcgtaaatt cctgcaacgg
    18601 gtagtccgat tgtaaaatct ttccgctcaa caggtaccat attaaagata cagactaaca
    18661 tttctccctt tttaccctta cgaataaagg aaagaacact ctggtctcga ttatccgcat
    18721 caatgatttc aataccatca tagctggtat caatttccca cagacagcga tgatctttgt
    18781 aaaactggtt tagctgagaa gcgaaatact tcatcttagc attcattggg tcttctaggt
    18841 tagaccattc caactgttct tcagatttcc attctaggaa ttgaccgtat tcgctaccca
    18901 tgaagagcaa tttcttacca gggtgacaaa tttggtacgt atagagattg cgcaagcctg
    18961 cgaattgatt gtaacgatct ccccacatct tatgcatcat actcttcttg ccatgaacca
    19021 cttcatcgtg cgagaatggc aagagataat tctccttgaa aacatacata aagctgaaag
    19081 tcaccaggtt aaagtcatat ttacgataga tcggatcttc ttcgtagaaa cggaggatat
    19141 cattcatcca gcccatgttc catttgtagt caaatcctag accaccaatc tctttcattc
    19201 ccgtaatctt gatcgcagac gaactttctt ctgcaatcat catcacatct ggatattcta
    19261 acttaataac ctcattcaag cgctgaagga aataataacc ttcatagttg agatttccgc
    19321 catctttatt aggtgtccat ggagcatcat catagtccaa atagagcatg ttgctaacag
    19381 catccacacg aataccatcc aaatgataga catcaatcca atgcttaatg caagaaatta
    19441 agaaggactg gacttcattt tttccaaggt caaaattaag ggcaccccaa ccatggttat
    19501 gagccttatt atggtcttgg tattcaaaag tcggtgtccc atcataatag gctaaggcat
    19561 catcgttgat ggtaaagtga cctggtaccc agtccacaat aaccccaata ttatgggtat
    19621 gacactcctc gacaaaatct tgaaactcct ctggtcggcc ataagcatgc tctaaagcga
    19681 agtaacccat aagctgatac ccccaactca agcccaaagg atgggacatc aagggcataa
    19741 actcaatatg agtatagttc atttcaacga gataaggaat gagttcatcc ttgagctggg
    19801 caaaactata aggactgcca tcagaatttc ttttccatga tccagcgtga acttcataaa
    19861 tattgacagg acgctcttca aagccccaac gttttcttcg tgccagccaa agtccatcct
    19921 tccatttctt ctcaggaagc tctgttacga ttgcccctgt tcctggacga gcctcatacc
    19981 tgacagcaaa agggtcaatc ttcatcagtt gatgaccatt ttgacgtgtg acatgatatt
    20041 tgtaaatatg cccttcttga gccatattgg taaagacttc ccagacccca aaatcatttc
    20101 ttaccattgg aatctgattt tcaatccagt tggtaaaatc accaaccaag tgaacagcct
    20161 gagcattagg tgcccaaaca cggaaggtat agccatgctc tccatttagt tcttccctat
    20221 gtgctcctag ataatgttgg agataaaaat tttcacccgt cataaaggtt tttaatgctt
    20281 ctctattatc catatactcc ccttctcctg taagcgtttt ctatgttttt attatactac
    20341 ctttttagag aagattcaag taaattacta tacttcttta attattttga aaatctacaa
    20401 caagttcact tactcgttca attgtaaatc aatatttttt caaaaaattg cgaaaacgcc
    20461 tttctttttc tactatagtg aaatgaaata aaacatgcgc aaatcgatta aggaatttaa
    20521 tctaatttct aacaatgtct tagaaatcaa agtgtactat tttaactcca atgtat
//
LOCUS       DAVFER010000039        20496 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1105170250
            SAMEA2167659-rid19724873.denovo.039, whole genome shotgun sequence.
ACCESSION   DAVFER010000039 DAVFER010000000
VERSION     DAVFER010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2167659
            Sequence Read Archive: ERR388902
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20496)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20496)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928716.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928716.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 04:07:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,118
            CDSs (total)                      :: 2,073
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 120
            CDSs (without protein)            :: 120
            Pseudo Genes (ambiguous residues) :: 0 of 120
            Pseudo Genes (frameshifted)       :: 67 of 120
            Pseudo Genes (incomplete)         :: 47 of 120
            Pseudo Genes (internal stop)      :: 34 of 120
            Pseudo Genes (multiple problems)  :: 23 of 120
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20496
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2167659-rid19724873.denovo.039"
                     /strain="1105170250"
                     /db_xref="taxon:1313"
     gene            96..344
                     /locus_tag="VU534_001539"
                     /pseudo
     CDS             96..344
                     /locus_tag="VU534_001539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017648301.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
     gene            358..698
                     /locus_tag="VU534_001540"
                     /pseudo
     CDS             358..698
                     /locus_tag="VU534_001540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812122.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            691..1071
                     /locus_tag="VU534_001541"
     CDS             691..1071
                     /locus_tag="VU534_001541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HEU1514111.1"
                     /translation="MIDLYLSKNRQRNQLLLDFFQNYGIEVSCHSVSEMTKDKLIEMM
                     SYSSDCFEFLSPNLLRFKNRDNLRLTDFVEIILKNPELTIRLPLAVSNKRVYPSLNLE
                     EARALLPRDTKQLIYMAQTHYLSN"
     gene            1084..1227
                     /locus_tag="VU534_001542"
     CDS             1084..1227
                     /locus_tag="VU534_001542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1514112.1"
                     /translation="MAERFWENLSIILAERNISWIELTRKMFAGEFHYPSELNRLYQK
                     IRH"
     gene            1320..1907
                     /locus_tag="VU534_001543"
     CDS             1320..1907
                     /locus_tag="VU534_001543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000821297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU1514113.1"
                     /translation="MKRIIPVYIFQQVNVLLVSLYLLKFLCIGELTILQILYGSSLIS
                     FLWMYGQRKQAHKVNMKSRMKWLGVEFVSLLIISLCFSLIHAQGSTNQANLIGLQHQI
                     PWFSFLLFLINASMVEEFLYREILWNLVRKLDIRVALTSVLFALAHHTGTILAWCLYV
                     SLGMFLGMVRYKSDLWGSMGLHLVWNLLVYSLLLF"
     gene            2306..3115
                     /locus_tag="VU534_001544"
     CDS             2306..3115
                     /locus_tag="VU534_001544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000926538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HEU1514114.1"
                     /translation="MLLQKELIPMIEANLPNMAYAEKDIAKFFLKQQPLNDYSSKALC
                     EYLNVSKATLTRFAKKCGFKGFRQFIFKYQEMIHEKEKLALYTEATEKVLSDYEEMLR
                     KTYTVLDEVQLERIAEMIETAERVYLYGKGSSVLALQEMKMRFMRLGVIGEVLSDEDM
                     ILWSSLLLNENCLVIGASISGQTDIVLEGLQKAADKGAKTVLMTTRKFDEEDCFFDEL
                     LLLASTDHLSYGNRISPQFPILLITDCLFSNYLESPERQYYYNQTIIHKEE"
     gene            3120..3821
                     /locus_tag="VU534_001545"
     CDS             3120..3821
                     /locus_tag="VU534_001545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HEU1514115.1"
                     /translation="MSQIWTKEKFISQVQGGVIVSCQALPGEALYNEEFSLMPFMAKA
                     ALEAGAVGIRANSVRDIKAIQKVVDLPIIGIIKRDYPPQEPYITATMKEVDELVECGT
                     TVIAFDATLRPRYDGLVVSEFIKKIKEKYPNQLLMADVSNLDEGLYAFKSGVDFVGTT
                     LSGYTSTSVQSDEPDFELMKKLADFNIPVIAEGKIHYPEQLKKAYSLGVTSVVIGGAI
                     TRPKEIAQRFINVIK"
     gene            3846..4763
                     /locus_tag="VU534_001546"
     CDS             3846..4763
                     /locus_tag="VU534_001546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylneuraminate lyase"
                     /protein_id="HEU1514116.1"
                     /translation="MKDLTKYKGVIPAFYACYDENGEISQDRVKSLVQYFIDKGVKGI
                     YVNGSSGECIYQSVEDRKQIIEAVMEVAKGKLTVINHIACNNTKDSIELAKHSESVGV
                     DAIAAIPPIYFKLPEYSIAAYWNAMSEAASNTDFIIYNIPQLAGVALTGSLYATMRQN
                     PRVIGVKNSSMPVQDIQMFVAAGGEDYIVFNGPDEQYLGGRLMGAEAGIGGTYGVMPD
                     LFLKLESLIQERDLDTAKKLQYAINEVIYKMISGKANMYAVAKEVLRLNEKLDLGSVR
                     QPLEALAEGDLEVAKQAAELIQQARKEFL"
     gene            4791..6332
                     /locus_tag="VU534_001547"
     CDS             4791..6332
                     /locus_tag="VU534_001547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000537364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:solute symporter"
                     /protein_id="HEU1514117.1"
                     /translation="MGTTGFTIIDLIILIVYLLAVLVAGIYFSKKEMKGKEFFKGDGS
                     VPWYVTSVSIFATMLSPISFLGLAGSSYAGSWILWFAQLGMVVAIPLTIRFILPIFAR
                     IDIDTAYDYLDKRFNSKALRIISALLFIIYQLGRMSIIMYLPSAGLSVLTGIDINILI
                     ILMGVVAIVYSYTGGLKSVLWTDFIQGVILISGVVLALFVLIANIKGGFGAVAETLAN
                     GKFLAANEKLFDPNLLSNSIFLIVMGSGFTILSSYASSQDLVQRFTTTQNIKKLNKML
                     FTNGVLSLATATVFYLIGTGLYVFYQVQNADSAASNIPQDQIFMYFIAYQLPVGITGL
                     ILAAIYAASQSTISTGLNSVATSWTLDIQDVISKNMSDNRRTKIAQFVSLAVGLFSIG
                     VSIVMAHSDIKSAYEWFNSFMGLVLGLLGGVFILGFVSKKANKQGAYAALIVSTIVMV
                     FIKYFLPPTAVSYWAYSLISISVSVVSGYIVSVLTGNKVSAPKYTTIHDITEIKADSS
                     WEVRH"
     gene            6351..6809
                     /locus_tag="VU534_001548"
     CDS             6351..6809
                     /locus_tag="VU534_001548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HEU1514118.1"
                     /translation="MIISEQSDFKRYASVNKYFSKVCDFLENTNLTDLVDGKIDIDGE
                     NVFANCMTYLADGVPGDIFETHKKYLDIHIVVENTEKMAVTSPVRAQSRVPFSEEKDI
                     AFYDSKDYQIVELLPGNMLVTFEEDLHQPKIHCNDETVKKLVIKVLNEEK"
     gene            6811..9033
                     /locus_tag="VU534_001549"
     CDS             6811..9033
                     /locus_tag="VU534_001549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000739354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exo-alpha-sialidase"
                     /protein_id="HEU1514119.1"
                     /translation="MKKNIKQYVTLGTVVVLSAFVANSVAAQETETSEVSTPKLVQPV
                     APTTPISEVQPTSDNSSEVTVQPRTVETTVKDPSSTAEETPVLEKNNVTLTGGGENVT
                     KELKDKFTSGDFTVVIKYNQSSEKGLQALFGISNSKPGQQNSYVDVFLRDNGELGMEA
                     RDTSSNKNNLVSRPASVWGKYKQEAVTNTVAVVADSVKKTYSLYANGTKVVEKKVDNF
                     LNIKDIKGIDYYMLGGVKRAGKTAFGFNGTLENIKFFNSALDEETVKKMTTNAVTGHL
                     IYTANDTTGSNYFRIPVLYTFSNGRVFSSIDARYGGTHDFLNKINIATSYSDDNGKTW
                     TKPKLTLAFDDFAPVPLEWPREVGGRDLQISGGATYIDSVIVEKKNKQVLMFADVMPA
                     GVSFREATRKDSGYKQIDGNYYLKLRKQGDTDYNYTIRENGTVYDDRTNRPTEFSVDK
                     NFGIKQNGNYLTVEQYSVSFENNKKTEYRNGTKVHMNIFYKDALFKVVPTNYIAYISS
                     NDHGESWSAPTLLPPIMGLNRNAPYLGPGRGIIESSTGRILIPSYTGKESAFIYSDDN
                     GASWKVKVVPLPSSWSAEAQFVELSPGVIQAYMRTNNGKIAYLTSKDAGTTWSAPEYL
                     KFVSNPSYGTQLSIINYSQLIDGKKAVILSTPNSTNGRKHGQIWIGLINDDNTIDWRY
                     HHDVDYSNYGYSYSTLTELPNHEIGLMFEKFDSWSRNELHMKNVVPYITFKIEDLKKN
                     "
     gene            9073..10182
                     /locus_tag="VU534_001550"
     CDS             9073..10182
                     /locus_tag="VU534_001550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEU1514120.1"
                     /translation="MVNYGIVGAGYFGADLARSMNKIEDAKVVAVFDPNHGEEVAQEL
                     GSDVCASLDELVAREDIDCVIVASPSYLHREPVVKAAQHGKHVFCEKPIALSYEDCKA
                     MVDACKENNVIFMAGHIMNFFNGVHHAKELITQGKIGKVLYCHAARTGWEEQQPTVSW
                     KKLRSQSGGHLYHHIHELDCIQFIMGGLPEKATMVGGNVYHKGENFGDEDDMLIVNLE
                     YSDDRYAVLEYGNAFRWGEHYVLIQGTEGAIKLDLFNTGGTLRVKGEGESHFLVHETQ
                     EEDDDRTAIYTGRGMDGAIAYGKPGVRCPLWLQTCIDKEMEYLHDIIKGGEITEEFEK
                     LLNGVAALESIATADACTLSVKEDRKVSLSEITNA"
     gene            10339..11229
                     /locus_tag="VU534_001551"
     CDS             10339..11229
                     /locus_tag="VU534_001551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEU1514121.1"
                     /translation="MKIIGIDIGGTTIKADLYDEFGTSLNHFKEIETIIDYDLGTNQI
                     LNQVCDLIGEYTLNHSIDGVGISTAGVVNANTGEIIYAGYTIPGYIGVNFTAEIEKRF
                     GLYTFVENDVNCAALGELWKGQAKDKKNVVMVTIGTGIGGSIIVNGQIVNGFNYTAGE
                     VGYIPVGNSDWQSKASTTALIHLYQKKSLKTNQTGRTFFTDLRSGDKVAEETFEIFVE
                     NLTKGLLTISYLLNPEILILGGGILDSKDILLPEIQSSLAKNAMDNRFLPKNLVAATL
                     GNEAGRIGAVKNFLDRISNK"
     gene            11254..11577
                     /locus_tag="VU534_001552"
     CDS             11254..11577
                     /locus_tag="VU534_001552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1514122.1"
                     /translation="MTNSVFSTMQDIENVATDIIKSYDNEIYTYKAVSQEELEKLEKS
                     YDEKSHEELVSIESNLEMKQQNLIDEVNKTIKENDANIQYISSSRRGEFVEKIIGRVV
                     EKYGH"
     gene            11567..13558
                     /locus_tag="VU534_001553"
     CDS             11567..13558
                     /locus_tag="VU534_001553"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit I"
                     /protein_id="HEU1514123.1"
                     /translation="MAISQMKRISLLFSKSSLDDVLKTIQELESVQFRDLKVQDNWSE
                     ALEKDEVVFPTIQIFHTSNSNHGVIEGNDALTYLMNQQQHLEATVEKLQEYLPKENTF
                     KLLQQPPITTSYEELEKFGKANVAEGVLKKVNHQINRVHELERHIQSNNEEIERLIKW
                     EKLEIVPANLEQFSFCKGKVGTIPRTEDNRLYNSLLENNIEVQEIFSNDREYGVVVFY
                     QSSYSIDFDEYLFEPFDYSRKELPKQRVVDLDQENMQLITEKENIIASLQDSKKYLID
                     LQWQIDYILSIYARQISKNNFLCTPHLVALEGWIEETRILYFIKVMDEHFGHSIYIYE
                     SETLTDNQDEIPIKLTNHSLIEPFELLTEMYALPKYYEKDPTPVLAPFYFTFFGMMVA
                     DLGYGLLLFLGTMLALKIFHLPSATKRFLKFFNILGVAVAIWGGIYGSFFGYELPFHL
                     ISTTSDVMTILVVSVVFGFITVFAGLLASGLQKVRMNKYAEAYNSGFAWCVILLGLLF
                     IAVGMLMPDMRPLFVLGKWVSIFNAVGILIVSIIQTKSLSGIGAGLFNLYNISSYIGD
                     LVSFTRLMALGLSGASIASAFNLIVGLFPGILAKLTIGLVLFILLHAINIFLSLLSGY
                     VHGARLIFVEFFGKFYEGGGKPFQPLKASEKYIKVITKN"
     gene            13574..14050
                     /locus_tag="VU534_001554"
     CDS             13574..14050
                     /locus_tag="VU534_001554"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit K"
                     /protein_id="HEU1514124.1"
                     /translation="MEHLATYFSTYGGAFFAALGIVLAVGLSGMGSAYGVGKAGQSAA
                     ALLKEQPEKFASALILQLLPGTQGLYGFVIGILIWLQLTPELPLEKGVAYFFVALPIA
                     IVGYFSAKHQGNVAVAGMQILAKRPKEFMKGAILAAMVETYAILAFVVSFILTLRV"
     gene            14084..14665
                     /locus_tag="VU534_001555"
     CDS             14084..14665
                     /locus_tag="VU534_001555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000067169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1514125.1"
                     /translation="MSNLENLRESVIEQAHEKGRMKLLDSKKKIDDEFEMQKSLIIKK
                     KEAEHERKLKELQQKYQIIFQQLKNKERQSTLVSKQKILKELFQSALLEMESWSADKE
                     MEFIYRILERYSQQEVIVTFGERTLAKFNLEQLEKLKFSFPNYLFSEQPISNESGLLI
                     SIGKIDDNYLYKTLIGSISKEESSSIANQIFIN"
     gene            14730..15737
                     /locus_tag="VU534_001556"
     CDS             14730..15737
                     /locus_tag="VU534_001556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000380539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATPase subunit"
                     /protein_id="HEU1514126.1"
                     /translation="MDTNLFSKINTTISVKENDFITEEKFQKIIQSKDTETLAFILES
                     TPYHLSIDILEDPSQTEISLMTKLVNDYRWAYAESPSDIIVTLFALRYVYHNIKVLLK
                     SKAAIKKDFSKLLIPIGIFDIESLKHLVSSLHSDTLPDFMVREVESIWNEYETFNNIR
                     VLDVGADLAYFKHLKLLSNELDEVLSQVIVEMIDFYNIITVKRGLSQNKSHGDILQLL
                     SDEGSISAKEFIYIVENQEIFVWFNKINPSLDSIFSTYELKMQDATISSSELEFLCDL
                     LLYKTLDQGRYNVEGPLVLARYLLGCEFEVKNLRMIISALQNTIPFESIKERIRPHYG
                     S"
     gene            15727..16047
                     /locus_tag="VU534_001557"
     CDS             15727..16047
                     /locus_tag="VU534_001557"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000387939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit F"
                     /protein_id="HEU1514127.1"
                     /translation="MEANKYKIGIIGSRDIILPFSMIGFDIFPAYQEQEAINTLRKLA
                     QSDYGVIYITEDIASMILDTIRHYDSQVVPAIILLPTHKQGLNLGLKRIEDNVEKAVG
                     HNIL"
     gene            16110..17885
                     /locus_tag="VU534_001558"
     CDS             16110..17885
                     /locus_tag="VU534_001558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit A"
                     /protein_id="HEU1514128.1"
                     /translation="MTQGKIIKVSGPLVIASGMQEANIQDICRVGKLGLIGEIIEMRR
                     DQASIQVYEETSGLGPGEPVVTTGEPLSVELGPGLISQMFDGIQRPLDRFKLATHNDF
                     LVRGVEVPSLDRDIKWHFDSTIAIGQKVSTGDILGTVKETEVVNHKIMVPYGVSGEVV
                     SIASGDFTIDEVVYEIKKLDGSFYKGTLMQKWPVRKARPVSKRLIPEEPLITGQRVID
                     AFFPVTKGGAAAVPGPFGAGKTVVQHQVAKFANVDIVIYVGCGERGNEMTDVLNEFPE
                     LIDPNTGQSIMQRTVLIANTSNMPVAAREASIYTGITMAEYFRDMGYSVAIMADSTSR
                     WAEALREMSGRLEEMPGDEGYPAYLGSRIAEYYERAGRSQVLGLPEREGTITAIGAVS
                     PPGGDISEPVTQNTLRIVKVFWGLDAPLAQRRHFPAINWLTSYSLYKDSVGTYIDGKE
                     KTDWNSKITRAMNYLQRESSLEEIVRLVGIDSLSDNERLTMEIAKQIREDYLQQNAFD
                     SVDTFTSFAKQEAMLSNILTFADQANHALELGSYFTEIMEGTVAVRDRMARSKYVSED
                     RLDEIKIISNEITHQIHLILETGGL"
     gene            17886..19271
                     /locus_tag="VU534_001559"
     CDS             17886..19271
                     /locus_tag="VU534_001559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000111247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit B"
                     /protein_id="HEU1514129.1"
                     /translation="MSVIKEYRTASEVVGPLMIVEQVNNVSYNELVEIQLHNGEIRRG
                     QVLEIHEDKAMVQLFEGSSGINLEKSKIRFAGHALELAVSEDMVGRIFNGMGKPIDGG
                     PDLIPEKYLDIDGQAINPVSRDYPDEFIQTGISSIDHLNTLVRGQKLPVFSGSGLPHN
                     ELAAQIARQATVLNSDENFAVVFAAMGITFEEAEFFMEELRKTGAIDRSVLFMNLAND
                     PAIERIATPRIALTAAEYLAFEKDMHVLVIMTDMTNYCEALREVSAARREVPGRRGYP
                     GYLYTNLSTLYERAGRLVGKKGSVTQIPILTMPEDDITHPIPDLTGYITEGQIILSHE
                     LYNQGYRPPINVLPSLSRLKDKGSGEGKTRGDHAPTMNQLFAAYAQGKKVEELAVVLG
                     ESALSDVDKLYVRFTKRFEEEYINQGFYKNRNIEDTLNLGWELLSILPRTELKRIKDD
                     LLDKYLPLVEV"
     gene            19294..19905
                     /locus_tag="VU534_001560"
     CDS             19294..19905
                     /locus_tag="VU534_001560"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000251933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit D"
                     /protein_id="HEU1514130.1"
                     /translation="MVRLNVKPTRMELNNLKERLTTAERGHKLLKDKRDELMRRFISL
                     IRENNQLRKEVESYLIDNLKSFAVAKSLKNSQMVEELFSIPSKEIELFVEKENIMSVT
                     VPRMHMNITSQNENSEYSYLSSNSEMDDVFATMNSLIYKLLRLAEVEKTCQLMADEIE
                     KTRRRVNGLEYSIIPNLSETIHYIELKLEEAERANLVRIMKVK"
     gene            20178..20363
                     /locus_tag="VU534_001561"
     CDS             20178..20363
                     /locus_tag="VU534_001561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001136123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1514131.1"
                     /translation="MPQPIVPVEIPQSRRFDSKKRNDILLKIRIGKLEVSFFQSLNLE
                     MVEQLLDKVLLYDNSSI"
     gene            20344..>20496
                     /locus_tag="VU534_001562"
     CDS             20344..>20496
                     /locus_tag="VU534_001562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HEU1514132.1"
                     /translation="MTIHLSSLGEVYLVCGKTDMRQGIDSLAYLVKTHFELDPFSGQV
                     FLFCGGR"
BASE COUNT         6895 a         2927 c         4055 g         6619 t
ORIGIN      
        1 aaagcaactc agttagttga tgaaatggaa caagtaggtt taatccgatt tgatgaattt
       61 ggaaatgttg gaattttagt cttggaggga caataatgaa gcgtattacc gctaatcaat
      121 atcagacatc agagcgttat tataagctcc ccaaactttt atttgagagt gaacggtata
      181 agaatatgaa actggaggtt aaggtggttt actcagtttt aaaagatcgg ttggagttgt
      241 ctttgagcaa aggttggatt gatgaggatg gggctattta tttgatttat tccaattcaa
      301 atttgatggc acttttaggc tgttcaaagt caaaattact ctccatgtga gtttgaagtg
      361 acatttttag atgattacca taaaaaacat aactacccac tattttacga atcctatctt
      421 caaaacgtta tggaattcct tgaaagtcaa gacataaaga atggggttga tgcctttgta
      481 gatgatcatc aaaatctcgt ttttgtttta tatggacaag gctatcgagc cgagggaaaa
      541 gagggaatac ttacaaccca agtaactgta aaagcttatg atgaagacaa gaaaccgatt
      601 aacttcgcaa atttattaga ttccttaatt tattagattc cttaatcgtg tcagaatatc
      661 aaatggaacc gaatctttgg gaggtctccc atgattgatc tctatctaag taaaaataga
      721 caaagaaatc aacttctttt agatttcttc caaaactatg gcatagaggt atcttgtcat
      781 tcagtttctg aaatgacaaa ggacaaatta attgagatga tgagctattc ttcagattgt
      841 tttgagtttt tatctcccaa tttattacga tttaagaacc gtgacaatct aagattaacg
      901 gatttcgttg agataatttt aaaaaatcct gaactaacca tcagacttcc tcttgcggtt
      961 tcaaataagc gagtttatcc aagtctgaat ttggaagagg ctagagctct attgccaaga
     1021 gatacgaaac aattgattta catggcgcaa acacattatt tatctaacta aaggagaagc
     1081 aatatggctg aacgattttg ggagaacttg tccattattt tggctgaaag aaatatcagc
     1141 tggattgagt taaccagaaa aatgtttgcg ggagagtttc actatccaag tgaattgaat
     1201 cgtttgtatc aaaagattcg ccactagaag atggaacaat gaatgcctca aagtccatgg
     1261 gtagaaagga ttgtgcaggt attagattta gattatgaag atttatttcg gaggtaacta
     1321 tgaaaagaat aattccagtt tatatattcc aacaagtaaa tgtcctattg gtatctctat
     1381 acttattgaa atttctttgt atcggtgagt taactatact acagattctc tatggttcgt
     1441 cactcatttc ttttttatgg atgtatggcc aacgcaaaca agcgcataag gtcaatatga
     1501 aatctaggat gaaatggctt ggtgttgaat ttgttagcct actgattata agtctatgtt
     1561 ttagtctgat tcatgctcaa ggaagcacga atcaagcaaa cttaattggc cttcaacatc
     1621 aaattccttg gttttcattt ttattgttct taatcaatgc gagtatggtt gaagaatttc
     1681 tgtatcgaga aattttatgg aatttggtca gaaaattaga tatcagagtt gctttgacaa
     1741 gtgttttatt tgccttagca catcatacag gaaccattct agcttggtgt ttgtatgttt
     1801 cacttgggat gtttttaggt atggtgcgct ataaatctga cttatggggc agtatgggac
     1861 tacatttggt gtggaaccta ctagtttata gtttgctgct tttttaaaat aggtgacctg
     1921 atttatctca taaatctgta gtttttatgg gattctcttt taatttagaa ataaaatata
     1981 ttacctatat aaaataaaga aactagaaat attttttcaa tttttttaga aataaaatat
     2041 tatatagaaa ttccgaaaag aaataataaa accaaaataa aatattacta aaatatttta
     2101 atatgaacat attattagtg ataaacgttc ttacaataca tataattacg ataaaaagaa
     2161 taaaaactat tatattttta tgtttgttgt tctgttatga aacgaaagaa attggaaact
     2221 agtttctaat ttatgaaaaa tattgaaaaa aaaaaaaagt gttaaaataa agaatgtaaa
     2281 cgtttacttc aactaaggag ctcatatgtt actgcaaaaa gaactaattc caatgataga
     2341 agctaactta ccaaatatgg catatgctga aaaagacatt gctaaattct tcttaaaaca
     2401 gcaacctctg aatgattatt catctaaagc attgtgcgaa taccttaatg tatccaaagc
     2461 aacattgact cgatttgcga aaaaatgtgg ttttaaaggt tttagacaat tcattttcaa
     2521 ataccaagag atgattcatg agaaagaaaa gttggcatta tatacagagg caacagaaaa
     2581 agttttatcc gactatgagg aaatgttgag aaaaacttac acggttcttg atgaagttca
     2641 acttgagcgt attgctgaga tgatagaaac tgctgagcgt gtatatctct acggtaaagg
     2701 aagttctgtt cttgctttac aagaaatgaa gatgagattt atgcgtctcg gagtgattgg
     2761 tgaagtatta tcagacgagg atatgatttt gtggagtagc ttactactta atgaaaattg
     2821 ccttgtcatt ggagcatcca tttcaggtca aactgatatt gtactagaag gtctacaaaa
     2881 agctgcagat aaaggcgcta aaacagtttt aatgactaca agaaaatttg acgaagaaga
     2941 ttgtttcttt gatgaactat tgttattagc ttcgaccgat catctctcgt atggcaatcg
     3001 catatcacct cagtttccaa tacttttaat tacagactgc ttattctcta attatctgga
     3061 aagtccagag agacaatatt attacaatca aactattatc cataaggagg aataataaaa
     3121 tgagccaaat ttggactaaa gaaaaattta taagccaagt tcaaggtgga gtcattgttt
     3181 cttgtcaagc tttacctggt gaagcccttt ataatgaaga atttagcttg atgcctttta
     3241 tggctaaagc agctttagag gcaggagcag tgggcattcg cgcaaattct gtgcgtgata
     3301 ttaaagcaat tcagaaagta gtagatttac caataattgg aattatcaaa agggattatc
     3361 cacctcaaga accatatatt actgctacga tgaaagaagt agatgaactt gtagaatgcg
     3421 gaacaacagt cattgcattt gatgcaactt taagaccaag atatgatggc ttagttgtca
     3481 gtgaatttat caaaaaaata aaagaaaaat atccgaatca attgctgatg gcggatgtaa
     3541 gtaatttaga tgaaggtctc tatgcattta aatcaggcgt tgattttgtt ggtacaacat
     3601 tatcaggtta cacaagtaca agtgtacaat cagatgagcc tgattttgaa ctaatgaaaa
     3661 aattggctga ttttaatatt ccggtaattg ccgaaggaaa aattcattat ccagaacaat
     3721 taaaaaaagc ttatagttta ggtgttacca gtgtagtcat tggtggagcg attacacgtc
     3781 caaaagaaat tgctcagcga tttattaatg tcatcaaata aaaaacaata taaaggagaa
     3841 atctgatgaa agatttaact aaatacaaag gcgttatccc tgcattttat gcttgctatg
     3901 atgaaaatgg tgaaattagc caagatcgtg taaaatctct ggtacaatat ttcattgaca
     3961 aaggtgtaaa aggtatctat gtaaatggtt cttcaggtga atgtatttac caaagtgtag
     4021 aagatcgtaa acaaattatt gaagctgtta tggaagttgc taaaggtaaa ttaacagtta
     4081 tcaaccatat tgcatgtaat aacacgaaag atagtatcga attggcaaaa cattcagaaa
     4141 gtgttggagt cgatgctatt gcagctatcc cacctattta tttcaaattg ccagagtatt
     4201 caatcgcagc atattggaat gcaatgagtg aagctgcgtc aaatacagat tttattatct
     4261 ataatattcc acaattggca ggggttgcgt tgactggtag tttgtatgca acaatgcgtc
     4321 aaaatcctcg tgtgattgga gttaaaaatt cttctatgcc tgtacaagat attcaaatgt
     4381 ttgtagctgc aggtggagaa gattacattg tattcaatgg tccagatgaa caatatcttg
     4441 gtggtcgctt gatgggagca gaagctggta ttggtggtac ttatggcgtt atgccagatt
     4501 tgttcttgaa attggaaagt ttgattcaag aacgagattt agatacagct aaaaaacttc
     4561 aatatgctat caatgaagtt atctataaga tgatatcagg taaggcaaat atgtatgctg
     4621 tagcaaaaga agttttgcgt ctaaatgaaa aacttgattt aggttctgtt cgtcaacctt
     4681 tagaagcatt ggcagaaggt gacttggaag ttgcaaaaca agcagcagaa cttattcaac
     4741 aagcacgaaa agaattttta taataaataa aatcaatatg gagatatgtt atgggcacaa
     4801 caggatttac aataattgac ttaattatct tgattgttta tttacttgcg gtgttggttg
     4861 caggtatcta tttctctaaa aaagagatga aaggaaaaga gttctttaaa ggagatggtt
     4921 cggttccttg gtatgttact tcggtatcca tttttgccac aatgctcagt ccgatttcct
     4981 tcttgggact cgctggtagc tcttatgcag gtagctggat tttatggttt gctcaattag
     5041 ggatggtagt agctattcca ctgacaattc gttttatctt acctatcttt gcacggatag
     5101 acatcgatac ggcatatgat tacttggata aacgttttaa ttctaaagca cttcgtatta
     5161 tttcagcact cttgtttatt atttatcaat tgggacgtat gtctatcatt atgtacctcc
     5221 catcagctgg tttatcagta ttgacaggaa ttgacatcaa tattttgatt attttgatgg
     5281 gtgtagttgc aattgtttat tcttatactg gtggtctaaa atccgtatta tggacagact
     5341 ttattcaagg tgtgattctg attagtggtg tcgttttagc tttatttgta ctgattgcta
     5401 atattaaagg tggctttggt gcagtagcag aaacattagc aaacgggaaa ttccttgctg
     5461 caaatgaaaa acttttcgat cctaacttgc tttcaaactc catcttttta attgtgatgg
     5521 gttcaggctt tacaatcttg tcttcctatg cttcatctca agatttggtt caacgtttta
     5581 ctacaacaca aaatattaag aaacttaata agatgttgtt cacaaacggt gttttgtcac
     5641 ttgcaactgc aacagtcttt tacttgattg gtacaggctt gtacgtattc tatcaagtac
     5701 aaaatgcaga tagtgcagct agcaatatcc ctcaagacca aatctttatg tactttattg
     5761 cataccagtt accagtaggt atcacaggtt tgatcttggc agcgatttat gcagcatctc
     5821 aatcaactat ttcaacaggt ttgaactctg ttgcaacttc atggacattg gatattcaag
     5881 atgtcatttc taaaaatatg tcagacaatc gtcgtacgaa aattgcacaa ttcgtatctc
     5941 tagcagtagg tttattctca attggtgttt ccattgtcat ggctcactca gatattaaat
     6001 ctgcatacga atggttcaat agtttcatgg gacttgtact tggtctactt ggtggtgtat
     6061 ttattcttgg atttgtttct aaaaaagcaa ataaacaagg tgcttatgca gcgctgattg
     6121 tatcaaccat cgtcatggta tttattaaat acttccttcc tccaacagct gttagctact
     6181 gggcatattc attgatttca atctctgtat cagtagtttc aggttatatt gtatctgttc
     6241 ttactggaaa taaagtatct gcacctaaat atacaacgat tcatgatatt acagaaatta
     6301 aagcggattc aagttgggaa gttcgtcact aatagaaaag agaaaataat atgattattt
     6361 ctgaacaatc tgattttaaa cgatatgctt ctgtcaataa atatttttca aaagtctgtg
     6421 attttttaga aaatacaaat ttgacagatt tagttgatgg aaaaattgat attgacgggg
     6481 aaaatgtttt tgcaaattgt atgacttatc tagctgatgg agttccagga gatatttttg
     6541 aaactcataa gaaatattta gatattcata ttgttgttga aaatactgaa aaaatggcag
     6601 taacttcccc agttcgtgcc cagtcacgtg taccttttag cgaagagaag gatattgctt
     6661 tttacgatag caaagactat caaattgttg aattgcttcc agggaatatg ttggtgactt
     6721 ttgaagaaga tcttcaccaa ccaaagattc attgcaatga tgaaactgtt aaaaaacttg
     6781 ttatcaaagt tttaaacgag gaaaaataaa atgaaaaaaa atattaaaca atatgtaacc
     6841 ttaggtactg tagtggtatt atcagcattt gttgctaact cagttgcagc tcaggagact
     6901 gaaacttctg aagtatcaac accaaagttg gtgcaacctg ttgcaccaac gactccgatt
     6961 tcggaagtac aacctacatc ggataactct tcggaagtta ctgtacaacc tcgaacagtt
     7021 gaaactactg ttaaggatcc atcttctaca gcggaagaaa ctcctgtctt agaaaaaaat
     7081 aatgttactt taacaggggg cggagaaaat gttactaaag agttaaagga taaatttact
     7141 agcggtgact ttactgtagt gattaagtac aatcagtcaa gtgagaaagg cttacaagct
     7201 ctgtttggaa tatctaattc caaacccggt caacaaaata gttatgtaga tgtgttcctt
     7261 agagacaatg gtgagttggg gatggaagcg cgtgatactt cttccaataa aaataaccta
     7321 gtatccagac ctgcttcagt ttggggtaag tacaaacaag aggctgtgac taacactgtt
     7381 gcagtagtag cagattcagt caaaaaaaca tattctttat acgcaaatgg tacaaaagta
     7441 gtagaaaaga aagtggataa tttcctaaac atcaaggata ttaaaggtat tgattactat
     7501 atgcttgggg gagtgaaacg tgcaggaaaa acggcgtttg gttttaacgg aacactagaa
     7561 aatatcaaat tctttaatag tgcattggat gaagaaactg ttaaaaagat gacaacaaac
     7621 gctgttactg gacatttaat ttatacggct aatgatacaa caggttctaa ctatttccgt
     7681 attccagttc tgtatacttt tagcaatggt cgggtatttt caagcattga cgctcgttac
     7741 ggtggaactc atgatttctt gaataaaatt aatattgcta caagttatag tgatgataat
     7801 ggtaagacat ggactaaacc aaaattaaca ttggcattcg atgattttgc gccagtacca
     7861 ttagaatggc ctcgtgaagt tggtggacgt gacttacaaa tcagcggtgg tgcaacctat
     7921 attgactctg ttattgttga aaaaaagaac aaacaagtac tcatgtttgc tgatgtgatg
     7981 cctgctggag taagttttag agaagcaact agaaaagatt caggttataa acaaattgat
     8041 ggtaattatt accttaaatt aaggaaacaa ggtgatactg attacaatta tactattcgt
     8101 gagaatggta ctgtatacga cgatcgtacc aacagaccaa ctgaattttc agtagataaa
     8161 aatttcggta ttaaacaaaa tggtaattat ttgacggtag agcaatattc ggtttcattt
     8221 gaaaataata aaaagactga atatcgtaat gggactaaag tccatatgaa tatcttctac
     8281 aaagatgcat tgtttaaagt agtgccaacg aactatattg catatatttc tagcaatgat
     8341 catggcgaat cttggtctgc accaacttta ttacctccta taatgggact taatcggaat
     8401 gcgccatatt taggtcctgg acgtggaatc attgaaagct caactggacg tattcttatt
     8461 ccgtcttaca ctggtaaaga gtctgcgttc atttatagtg acgataatgg agcatcttgg
     8521 aaagttaaag tagtgccact tccttctagt tggtcagcag aagcacaatt tgtagaattg
     8581 agtccaggag taattcaagc atatatgcgt acaaataatg gtaaaattgc atatttaaca
     8641 agtaaagacg caggtactac ttggagtgca ccggaatatt tgaaatttgt ttcaaatcca
     8701 agttatggaa cacaattatc aatcatcaat tatagccaat tgattgatgg taaaaaggct
     8761 gtcattttaa gtactccaaa ctccacaaat ggtcgtaaac acggacaaat ttggattggt
     8821 ctaattaatg atgataatac aattgattgg cgttatcatc acgacgttga ttatagtaac
     8881 tatggatact catattcaac attgacagag ttaccaaatc atgaaattgg attgatgttt
     8941 gaaaaatttg attcatggtc tcgtaatgaa cttcatatga aaaatgttgt accatatata
     9001 acatttaaga ttgaagatct gaaaaagaat taaagctgaa atttgaaaat atataaaaag
     9061 aggataaaaa ttatggtaaa ttacggtatt gttggagctg gatattttgg agctgattta
     9121 gctcgctcaa tgaacaaaat tgaagatgca aaagtggttg cggtatttga cccaaatcat
     9181 ggagaagaag ttgctcaaga gttgggatca gatgtttgtg caagtttaga tgaacttgta
     9241 gcacgtgaag atattgattg tgtgatcgta gcttcaccta gctaccttca ccgtgaacca
     9301 gttgtgaaag ctgctcaaca tggcaaacac gtattttgtg aaaagccaat tgcattgtct
     9361 tatgaagatt gtaaagccat ggttgacgca tgtaaagaaa ataatgtcat ctttatggct
     9421 ggtcacatca tgaacttctt taacggtgta caccatgcta aagaattgat tactcaaggt
     9481 aaaatcggta aagttcttta ttgccatgct gctcgtacag gttgggaaga acaacaacca
     9541 actgtatcat ggaagaaact tcgttctcaa tctggaggac atttgtacca ccatattcat
     9601 gaattagatt gcattcagtt tatcatggga ggacttcctg aaaaagcgac aatggtagga
     9661 ggcaatgtat atcataaagg tgaaaacttt ggtgatgaag atgatatgct cattgtaaac
     9721 ttagaatact ctgatgatcg ttatgctgtt ttggaatatg gtaatgcttt ccgttggggt
     9781 gaacactacg tcttgattca aggaactgaa ggagctatca aacttgactt gttcaatact
     9841 ggcggtactc ttcgtgttaa aggtgaagga gaatcacact tcttagttca tgaaactcaa
     9901 gaggaagatg atgatcgtac agctatctat accggtcgtg gtatggatgg agcaattgcg
     9961 tacggtaaac caggagtacg ttgcccatta tggttgcaaa catgtattga taaagaaatg
    10021 gaatatctac atgacatcat taaaggtgga gaaattacag aagaatttga aaaacttctc
    10081 aatggtgtag ctgctttaga atcaatcgct accgctgatg catgtacttt atcagttaaa
    10141 gaagatcgaa aagtaagtct ttcagaaatc acaaatgctt aacttttgta aaacagaata
    10201 gtaaattctt gtcattatat aatttctaaa gttctgtgat acaactcatt gaataaagaa
    10261 atagagatgg gactgggata atgcccagtc ccatttttta tcaaaaagta atgagatcaa
    10321 aaatgtggga gtgttgaaat gaagattata ggtatcgata ttggcggaac aacaattaag
    10381 gcagatttat acgatgagtt tggaacgagt ttgaatcatt tcaaagagat agaaacaatt
    10441 attgactatg atttgggaac gaatcagata ttaaatcagg tctgtgattt aattggtgag
    10501 tatactttaa atcattcaat tgatggtgtt gggatttcca ctgctggagt tgttaatgct
    10561 aatactggag aaatcatcta tgcaggctat acaataccag ggtatatcgg agtaaacttt
    10621 actgccgaaa tagaaaaacg ttttgggttg tatacttttg ttgaaaatga tgttaattgt
    10681 gctgcattag gtgaattgtg gaagggacaa gccaaagata agaaaaatgt agtaatggtt
    10741 actattggaa caggtatagg aggcagtatt attgtcaacg gacaaattgt taacggattt
    10801 aactatactg ctggtgaagt aggttatatt cctgtaggta attcggattg gcaaagtaaa
    10861 gcctcaacaa ccgcattgat tcatttatat caaaaaaaga gcttgaaaac taatcaaact
    10921 ggacgtactt tcttcactga tttaagatct ggagataaag ttgctgaaga aacttttgaa
    10981 atttttgtag aaaatctaac aaaaggttta ttaacgattt cttatctact taatccagaa
    11041 attctcatat taggaggtgg gattctggat agtaaggata ttttgttacc tgaaattcaa
    11101 agttctttag ctaaaaatgc aatggataat aggtttttac ctaaaaatct tgtggcagct
    11161 acattaggaa atgaagctgg tcgtatagga gctgtaaaaa atttcttaga tagaatttct
    11221 aataaatagt atgtaagata aggaggtgtc acaatgacta actctgtatt ttcgacaatg
    11281 caagatattg agaatgttgc aaccgatatt ataaaatcat atgataatga gatttatact
    11341 tataaagctg tttcccaaga agaattggaa aaactagaaa aaagttatga tgaaaaaagt
    11401 cacgaagaat tagtttcaat agaaagcaat ttagaaatga aacaacagaa ccttattgat
    11461 gaggttaata aaacaatcaa ggaaaatgat gcaaatattc agtatatttc atcaagtagg
    11521 agaggagaat ttgtagaaaa aattattggt agggtggtag aaaaatatgg ccattagtca
    11581 gatgaaaaga atctctctac tattttctaa aagtagtctt gatgatgttt taaaaactat
    11641 tcaagaacta gagtcagtgc agttccgtga tttaaaggtt caggataact ggtcagaagc
    11701 tctagaaaaa gatgaagttg tatttccaac tattcaaatt tttcatactt ctaattccaa
    11761 tcatggggtt attgagggaa atgatgcctt gacttatttg atgaatcaac aacaacattt
    11821 agaagcaact gtagagaaat tacaagaata cctaccgaaa gaaaacacgt ttaaattatt
    11881 gcagcaacct ccgataacta cctcttatga agaattagag aaatttggta aagctaatgt
    11941 tgctgagggt gttcttaaaa aagtgaatca tcaaattaac agagttcatg aattagaaag
    12001 acacattcaa agtaataatg aggaaataga gcgattaata aagtgggaaa aattagaaat
    12061 tgttcctgcg aatttagaac aattttcttt ctgtaaagga aaagtcggaa caattccaag
    12121 gactgaagat aatcgcttat acaatagtct tttagaaaac aatattgaag ttcaagaaat
    12181 attttctaat gatagagagt acggtgttgt tgttttctat cagtctagtt actctataga
    12241 ttttgatgaa tacttatttg aaccatttga ttattctaga aaggaattac cgaagcagcg
    12301 agtagtagat ttagatcaag aaaacatgca gttaataact gaaaaagaga atattatcgc
    12361 atcgttgcaa gattcaaaga aatatttgat agatttacaa tggcaaatag actatatttt
    12421 atctatctat gctcgtcaaa tctctaagaa taactttttg tgcactccgc atctagttgc
    12481 attagaagga tggatagaag aaactcgtat tttatatttt ataaaagtta tggatgagca
    12541 ttttggacat tctatttata tttatgaatc ggaaacattg acggataatc aagatgaaat
    12601 acctatcaaa ttaacgaatc attctttaat tgaaccattt gaattattga cagaaatgta
    12661 tgctctgccc aaatattatg agaaagatcc tacacctgta ttagcaccat tttactttac
    12721 attttttgga atgatggttg ctgatttagg ctatggttta ctattgtttt taggaacaat
    12781 gttagcatta aaaatttttc atctaccttc agcaactaag agatttttaa aattctttaa
    12841 tatattaggg gtagccgttg caatttgggg tggaatctat ggctcatttt ttggatatga
    12901 gttgccattt catctgatat ctacaacctc tgatgtcatg actatattag tagtgtcagt
    12961 tgtgtttggg tttattacag tatttgcagg tttgttagct tcaggactac aaaaagtaag
    13021 aatgaataaa tatgcagaag catataattc aggatttgcg tggtgtgtta ttctgcttgg
    13081 cttgttattt attgctgttg gaatgttgat gcctgatatg agaccgttat ttgtattagg
    13141 gaaatgggta tctattttta atgctgtggg gattttgatt gtttctatta ttcaaaccaa
    13201 aagcttgtca ggtattggag caggattgtt taatctatat aacatttcat cttatatagg
    13261 tgatttagtt agtttcactc gattgatggc attaggatta tctggagcaa gtatagcatc
    13321 agctttcaat ttaattgttg gtttgtttcc gggaatattg gctaaactga caattggatt
    13381 agtattattc attcttttac atgcgatcaa tatttttcta tcgttactat caggatatgt
    13441 tcatggagca cgtctgatat ttgttgaatt ttttggtaag ttttatgagg gtggaggaaa
    13501 accatttcaa cctttgaagg cttctgagaa atatattaag gttattacaa agaattaatg
    13561 gaggatatat ataatggaac atttagcaac ttatttttca acctatggag gagctttctt
    13621 cgctgcattg ggaattgtat tggcggttgg attaagcggt atggggtctg cttatggagt
    13681 tggtaaggct gggcaatctg ccgcagcttt actgaaagaa cagcctgaaa agtttgcctc
    13741 agctttgata ttgcaattat tgcccggaac acaaggatta tatggttttg ttattggaat
    13801 tttaatttgg ttgcaattaa ctccagaact tcctttagaa aaaggcgttg cttatttctt
    13861 tgtagctctt ccaattgcta ttgtaggata cttttcagct aagcatcaag gaaatgtagc
    13921 agtagcggga atgcaaatct tggctaaaag accaaaagaa ttcatgaagg gagcaatttt
    13981 agctgccatg gtagaaacct atgcaattct tgcttttgtc gtatcattca ttttgaccct
    14041 tcgtgtataa gaaataaatt tgcaattcaa aggaggtgtc taaatgagca atttagaaaa
    14101 cttacgagag tctgttattg aacaagctca tgaaaaaggg cgtatgaaat tattggattc
    14161 caaaaagaag attgatgatg aatttgaaat gcaaaagtcg ctcattataa agaaaaaaga
    14221 agctgaacat gaacgaaagt taaaagaatt gcaacagaaa tatcaaataa tttttcaaca
    14281 attaaaaaat aaggaacgcc aatcaacgtt agtatcaaaa cagaaaatat taaaagaact
    14341 ttttcaatct gctttactag aaatggaatc ttggagtgca gataaagaaa tggagttcat
    14401 ctatcgaatt ctggaacgat attcacaaca agaggtcata gtaacctttg gggaacggac
    14461 tttagctaaa ttcaatttgg aacaattaga gaaattgaaa ttctcttttc caaattattt
    14521 atttagtgaa caacctatct caaatgaatc aggcttactt atttcaatag gtaaaattga
    14581 tgataactat ttgtataaaa cattaattgg atcgatttct aaggaagaaa gttcaagtat
    14641 cgcaaatcaa atttttatca attaaggatg aaattggtta atccttctta gaaatttgga
    14701 gtattccaat aaaattagaa aggtatttta tggatactaa tcttttttca aaaataaata
    14761 cgacgatttc ggtaaaagaa aacgatttta ttacagaaga aaaatttcaa aaaattatac
    14821 aatccaaaga tacggagaca ttggcattta tcttagaatc aactccctat catttatcga
    14881 ttgacatctt agaagatcct agtcagacag agatttcgct aatgacaaaa ttagtcaatg
    14941 attatagatg ggcctatgct gaaagtccgt ctgatataat tgtgacttta tttgctttac
    15001 gatatgttta tcataatatc aaagttttat taaaatctaa ggcggcaatt aagaaagatt
    15061 tttctaaatt attaattcca atagggattt ttgatataga aagtttaaaa catttagttt
    15121 cttccttaca ttcagataca cttcctgatt ttatggttcg tgaagtagaa tcaatttgga
    15181 atgagtatga aacttttaat aatattcgtg tacttgatgt cggagctgat ctagcatatt
    15241 ttaaacatct gaaactttta tctaatgagt tagatgaggt actgtctcag gttattgtcg
    15301 aaatgattga cttttataat attattactg taaaacgtgg tttatctcaa aataagagtc
    15361 atggggatat tttacaatta ctttcagatg aaggaagtat ttctgctaaa gaatttatat
    15421 acattgtaga aaatcaagaa atatttgtgt ggttcaataa aataaatcca agcttagatt
    15481 caatcttttc aacttatgaa ttgaagatgc aggacgcaac aatttcatct tctgagttag
    15541 aatttttatg tgatttacta ttgtataaaa ctttagatca aggaaggtac aatgtagagg
    15601 ggccgttagt tcttgctaga tatttattgg gatgtgagtt tgaagtaaag aatctcagaa
    15661 tgatcatatc agctcttcaa aatacaattc cctttgaatc aataaaagaa aggatacgcc
    15721 cacattatgg aagctaataa gtataaaatt ggcataattg gtagccgtga tattatttta
    15781 ccatttagca tgattgggtt tgatatattt cctgcctacc aagaacaaga agctataaat
    15841 acactaagaa aattagctca atctgattat ggtgtcattt atatcactga agacattgct
    15901 tcaatgatat tagatacaat tcgccattat gattcccaag ttgtgcctgc tattatttta
    15961 ttaccgactc ataaacaagg tttaaattta ggattaaaac gtatagagga taatgtagag
    16021 aaagcagtag gacacaatat tttataataa tgtacaaaat tgtctgtaat attattctat
    16081 aatttttgga cttagtaagg agaataactt tgactcaagg gaagattata aaagtatcgg
    16141 gacctctagt tattgcatca ggtatgcagg aggctaatat tcaagatatt tgccgtgtag
    16201 gtaagctagg gttaatcggt gaaattattg aaatgagaag agatcaggca tctatccaag
    16261 tctatgaaga aacatctggt cttggtccgg gagaacctgt tgttacaact ggagaacctc
    16321 tctcggttga attagggcca ggattgattt ctcaaatgtt tgatggcata caacgcccat
    16381 tagatcgatt taaattggct actcataatg attttctagt tcgtggggta gaagttccaa
    16441 gtttggatag agatattaag tggcattttg attccactat agcaattggt caaaaagtga
    16501 gtacgggtga tattcttgga actgtcaagg aaaccgaggt agttaatcat aaaattatgg
    16561 ttccttatgg agtatctgga gaagtcgttt ctattgcatc tggcgatttt acaattgatg
    16621 aagttgtata tgaaataaaa aaattggacg gtagtttcta taaaggaacg cttatgcaaa
    16681 aatggcctgt ccgcaaggcg cgtcctgttt ctaaacgttt aattccagaa gaaccattaa
    16741 tcacaggtca acgagttatt gatgcattct ttccagtaac caaaggggga gctgcagcag
    16801 ttcctggacc gtttggagca ggaaagacag ttgtacaaca ccaagtagct aaatttgcca
    16861 atgttgatat tgttatttat gtcggttgtg gagaacgtgg aaatgaaatg acggatgtac
    16921 tgaatgagtt tcctgagttg attgacccta ataccggaca atcaattatg caacggacag
    16981 ttctgattgc taatacttca aatatgcctg ttgctgctcg tgaggcttca atttatacag
    17041 gaattaccat ggctgagtat tttcgtgata tgggctactc tgtcgccatt atggctgatt
    17101 caacttcacg ttgggcagaa gcgctacgtg aaatgtcagg acgtctagaa gaaatgcctg
    17161 gtgatgaggg ttatcctgct tatctgggaa gtcgtatcgc tgaatattat gaaagagcag
    17221 gacgttctca ggttctaggg cttccagaac gtgaaggaac gattactgct attggagctg
    17281 tatcgccacc tggtggagat atttcagaac cagttactca aaacacttta cggattgtga
    17341 aagttttttg ggggcttgat gctccgttgg cacagcgacg tcattttcct gcaattaact
    17401 ggcttacatc ttattcacta tataaagaca gtgtgggcac ttatatagat ggtaaagaga
    17461 agacagattg gaatagtaaa ataactcgtg cgatgaacta cttacaacgg gaatctagtt
    17521 tagaggaaat tgttcgtctt gttggaattg attctctgtc tgataatgaa cgactaacga
    17581 tggaaattgc taaacaaatt cgagaagatt atttgcaaca gaacgctttt gattcggtag
    17641 atacattcac ttcgtttgca aaacaagaag caatgctaag taatattctc acttttgctg
    17701 atcaggcaaa tcatgcttta gagttgggtt cttactttac agagattatg gaaggtaccg
    17761 tggcagttcg agaccgtatg gcgagaagta aatatgtttc agaagataga ttagatgaaa
    17821 tcaaaattat atcaaatgag attacacatc aaattcattt gatattagaa acaggaggtc
    17881 tataaatgag tgttataaaa gaatacagaa ctgctagtga agttgttggg cctcttatga
    17941 ttgttgaaca agtaaataat gtgtcttaca atgagttagt tgaaattcaa cttcataatg
    18001 gagaaattcg tcgtggacaa gttttagaga tccacgaaga taaagcaatg gttcagcttt
    18061 ttgaaggatc tagtggaata aatttagaaa agtctaaaat tcgttttgct ggtcatgcat
    18121 tagaattggc tgtatctgag gatatggttg gtcgtatttt taatgggatg ggaaaaccaa
    18181 ttgatggtgg accagattta attccagaga aatatttaga tattgatggt caagctatta
    18241 atcctgtatc tagagattat ccagatgaat ttattcagac agggatctcc tctattgatc
    18301 atttgaatac tcttgtacgt ggtcaaaaat taccagtatt ttcaggttcg ggcttacctc
    18361 ataatgaatt agctgctcag atagcaagac aagcgactgt tttaaattct gatgaaaatt
    18421 ttgcggttgt atttgcagca atgggtatta cttttgaaga agctgagttt tttatggaag
    18481 aactcagaaa aacaggagcg atcgatcgtt cggttttatt tatgaacttg gcaaatgatc
    18541 ctgcaattga gcgtattgca actccccgca ttgctttaac tgcggcagag tatctagctt
    18601 ttgaaaaaga tatgcacgtt ctagttatca tgacggatat gactaactat tgtgaagcgt
    18661 tacgtgaagt ctcggcagct cgccgtgaag ttccagggag acgaggctat ccgggatatt
    18721 tatatacaaa tttatcaact ctatacgaaa gggctggtcg cttagttggt aaaaaaggtt
    18781 cggtgacaca gattcctatt ttaacaatgc cagaagatga cataacacat ccaattcctg
    18841 atttaactgg atacattact gaagggcaaa ttattttgtc gcatgagttg tataatcaag
    18901 gttatcgtcc accaatcaat gttttacctt ctctctctcg attaaaagat aagggatctg
    18961 gagaaggtaa aactcgtgga gatcatgctc caactatgaa tcaactgttt gcagcctatg
    19021 cccaagggaa aaaggttgaa gagttagcag tagtattagg agaatcggct ttatctgatg
    19081 tagataaatt gtatgtgagg tttacaaagc gttttgaaga agagtacata aaccaaggat
    19141 tttataaaaa tcgaaatata gaagatacgt tgaatcttgg gtgggaatta ctatcaattc
    19201 ttcctagaac agagttaaaa cgtatcaaag atgatttgct tgataaatac ttacctttgg
    19261 tagaagttta atccggaaat ggagtgatta tctatggtac gtttgaatgt aaaaccaact
    19321 cgtatggaat tgaataactt aaaggaacgt ttgacaacag ctgaacgtgg acataagtta
    19381 ttaaaggata aaagagatga attgatgagg cgatttattt ctttgattcg tgagaataat
    19441 caacttcgga aagaagtgga aagttatcta attgataatc taaaatcctt tgcagttgct
    19501 aaatcattaa agaattctca aatggtggag gaattatttt caattccatc gaaagaaatt
    19561 gaattatttg ttgagaaaga aaatatcatg agtgtaacag ttcctagaat gcatatgaat
    19621 attacttctc aaaatgagaa cagtgaatac agctatttat cttctaatag tgaaatggat
    19681 gatgtatttg ctacaatgaa tagtttaatt tataaattac taagactggc agaagttgaa
    19741 aaaacgtgtc agttaatggc tgatgaaata gaaaaaacac gtagacgtgt aaatggttta
    19801 gaatactcga ttattccaaa cttgtcggaa actattcatt atatagaatt gaaactagag
    19861 gaggcagaaa gagccaattt agttcgtatt atgaaagtga agtagatcct ttatttagat
    19921 tattaattag atgaacaaat atcagcttgg ataaggcttt aagcctttct aagctttttt
    19981 tattgacagt atcaggatat ctttttcaaa attttggttt gttagataat gaaaatgttt
    20041 ctactaatct agatttagga ttagtaaatc gtaaatgtaa ttatatagaa agtaagcgcg
    20101 tcataacaag gtatctatca ttcatggagc tcctcctgta tactattagt aaagtaaaac
    20161 tattggagga tattttaatg ccacaaccta ttgttcctgt agagattcca caatctcgtc
    20221 gttttgattc taaaaagaga aatgatattc tgcttaaaat tcgtattggc aagcttgaag
    20281 taagtttttt tcaatctctc aatctcgaaa tggtagaaca gcttttggat aaggtgttgc
    20341 tctatgacaa ttcatctatc tagcctaggg gaggtctatc tcgtgtgtgg gaaaactgat
    20401 atgagacaag gaatcgattc actggcttat ctggttaaaa cccactttga attggatcct
    20461 ttctccggtc aagtctttct cttttgtggt ggacgt
//
LOCUS       DAVFER010000040        18755 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1105170250
            SAMEA2167659-rid19724873.denovo.040, whole genome shotgun sequence.
ACCESSION   DAVFER010000040 DAVFER010000000
VERSION     DAVFER010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2167659
            Sequence Read Archive: ERR388902
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18755)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18755)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928716.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928716.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 04:07:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,118
            CDSs (total)                      :: 2,073
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 120
            CDSs (without protein)            :: 120
            Pseudo Genes (ambiguous residues) :: 0 of 120
            Pseudo Genes (frameshifted)       :: 67 of 120
            Pseudo Genes (incomplete)         :: 47 of 120
            Pseudo Genes (internal stop)      :: 34 of 120
            Pseudo Genes (multiple problems)  :: 23 of 120
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18755
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2167659-rid19724873.denovo.040"
                     /strain="1105170250"
                     /db_xref="taxon:1313"
     gene            1..73
                     /locus_tag="VU534_001563"
     tRNA            1..73
                     /locus_tag="VU534_001563"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:34..36,aa:Met,seq:cat)
     gene            87..160
                     /locus_tag="VU534_001564"
     tRNA            87..160
                     /locus_tag="VU534_001564"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:121..123,aa:Ile,seq:cat)
     gene            171..260
                     /locus_tag="VU534_001565"
     tRNA            171..260
                     /locus_tag="VU534_001565"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:207..209,aa:Ser,seq:tga)
     gene            274..347
                     /locus_tag="VU534_001566"
     tRNA            274..347
                     /locus_tag="VU534_001566"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:308..310,aa:Met,seq:cat)
     gene            351..423
                     /locus_tag="VU534_001567"
     tRNA            351..423
                     /locus_tag="VU534_001567"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:384..386,aa:Phe,seq:gaa)
     gene            443..513
                     /locus_tag="VU534_001568"
     tRNA            443..513
                     /locus_tag="VU534_001568"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:475..477,aa:Gly,seq:tcc)
     gene            549..622
                     /locus_tag="VU534_001569"
     tRNA            549..622
                     /locus_tag="VU534_001569"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:583..585,aa:Ile,seq:gat)
     gene            629..716
                     /locus_tag="VU534_001570"
     tRNA            629..716
                     /locus_tag="VU534_001570"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:663..665,aa:Ser,seq:gct)
     gene            complement(842..1777)
                     /locus_tag="VU534_001571"
     CDS             complement(842..1777)
                     /locus_tag="VU534_001571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000844514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional biotin--[acetyl-CoA-carboxylase]
                     synthetase/biotin operon repressor"
                     /protein_id="HEU1514133.1"
                     /translation="MKSYQAVYQILSKETDYISGEKIAEKLSLSRTAIWKAIKRLEQE
                     GIEIDSIKNRGYKLMNGDLILPEILEENLPIKVSFKPETKSTQLDAKEAIDLGHEANT
                     LYLASYQTAGRGRFQRSFYSPQGGIYMTLHLKPNLPYDKLPSYTLLVAGAVYKAIKNL
                     TLIDVDIKWVNDIYLNNHKIGGILTEAMTSVETGLVTDIIIGVGINFTIKDFPQELKE
                     KAASLFKATAPITRNELIIEIWRAFFETPAEELLYLYKKQSFILGKEVTFTLEQKDYK
                     GLAKDISENGKLLVQCDNGKEIWLNSGEISLNSWK"
     gene            complement(1774..2634)
                     /locus_tag="VU534_001572"
     CDS             complement(1774..2634)
                     /locus_tag="VU534_001572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000959966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HEU1514134.1"
                     /translation="MLVFSEYQTGTIDLALSFYGYEECTPNYSFGPAIRDTYVLHYIT
                     KGQGKFHYKGKIVDLKEGDFFLLKPEELTFYQADSKEPWAYYWLGITGGKAPDYFALS
                     QISDQSYLIQSETCHTQTTAKLISDIVRFAQITKSSELAQLHIMGQLHELMFHLGTIA
                     PNQKKKNISSTHQLYLECKRLIDSHYPQSLTIQDLAKELSVHRSYLSSVFKEFNTLSP
                     KEYLLYVRMHRARQLLENTQESIKVIAYSVGFSDPLHFSKAYKQYFNQTPSHTRKEYS
                     QYQLVRKATL"
     gene            2742..4904
                     /locus_tag="VU534_001573"
     CDS             2742..4904
                     /locus_tag="VU534_001573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000538915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HEU1514135.1"
                     /translation="MGVRIENNLFYVESKNLSLIIENRNGYLLLKHLGKTIKNYKGSN
                     SVYERDHAFSGNPTATNRTFSLDTQRQIFGQHGLGDFRKPTIQVQHSVTEVTDFRFVE
                     AKILKGQNGPQGLPSPHSMDDTETLVLMLEDSKAQLSLTLYYTTFNNDATIASYSKLD
                     NNSNQEVVIHKDFSFMADFPAADYEIVTLQGAYAREKTVRRQQVEQGIFSISSNRGAS
                     GHAQTPALLLCEQGVTEDAGNVFAIQLMYSGNFEAFVQKNQLNEVRVAIGINPENFSW
                     KLAPEEYFETPVALVTHSDQGLTGISHESQNFVLKHIMLSEFSKKERPILINNWEATY
                     FDFQREKLLELADEAKKVGIELFVLDDGWFGNRFDDNRALGDWVVNEEKLGGSLESLI
                     SAIHERGLQFGLWLEPEMISVDSDLYRQHPDWAIQVPGYEHTYSRNQLVLNLANPQVV
                     EYLKSVLDQLLFYHDIDYIKWDMNRNITKLGNGLTYLETQMQSHQYMLGLYELVSYLT
                     EKHSHILFESCSGGGGRNDLGMMRYFPQVWASDNTDAIARLPIQYGSSYLYPTISMGA
                     HVSAVPNHQMGRMTPLETRGLVAMMGNLGYELDLTNLSDEEKATIANQVNLYKELRPV
                     VQLGQQYRLINPDTVSNEAAVQFNYGNQTIVTYVRVLSVVETMETTLKLKDLDEEGLY
                     KLQENGEVYSGAELMYAGLTVILSQGDFLSRQYIFRKL"
     gene            4996..6255
                     /locus_tag="VU534_001574"
     CDS             4996..6255
                     /locus_tag="VU534_001574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEU1514136.1"
                     /translation="MEWYKKIGLLATTGLALFGLGACSNYGKSADGTVTIEYFNQKKE
                     MTKTLEEITRDFEKENPKIKVKVVNVPNAGEVLKTRVLAGDVPDVVNIYPQSIELQEW
                     AKAGVFEDLSNKDYLKRVKNGYAEKYAVNEKVYNVPFTANAYGIYYNKDKFEELGLKV
                     PETWDEFEQLVKDIVAKGQTPFGIAGADAWTLNGYNQLAFATATGGGKEANQYLRYSQ
                     PNAIKLSDPIMKDDIKVMDILRINGSKQKNWEGAGYTDVIGAFARGDVLMTPNGSWAI
                     TAINEQKPNFKIGTFMIPGKEKGQSLTVGAGDLAWSISATTKHPKEANAFVEYMTRPE
                     VMQKYYDVDGSPTAIEGVKQAGEDSPLAGMTEYAFTDRHLVWLQQYWTSEADFHTLTM
                     NYVLTGDKQGMVNDLNAFFNPMKADVD"
     gene            6269..7135
                     /locus_tag="VU534_001575"
     CDS             6269..7135
                     /locus_tag="VU534_001575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEU1514137.1"
                     /translation="MKKVLQKYWAWAFVVIPLLLQAIFFYVPMFQGAFYSFTNWTGLT
                     YNYKFVGLNNFKLLFMDPKFMNAIGFTAIIAIAMVVGEIALGIFIARVLNSKIKGQTF
                     FRAWFFFPAVLSGLTVALIFKQVFNYGLPAIGNALHIEFFQTSLLGTKWGAIFAAVFV
                     LLWQGVAMPIIIFLAGLQSIPTEITEAARIDGATSKQVFWNIELPYLLPSVSMVFILA
                     LKGGLTAFDQVFAMTGGGPNNATTSLGLLVYNYAFKNNQFGYANAIAVILFFLIVVIS
                     IIQLRVSKKFEI"
     gene            7149..7982
                     /locus_tag="VU534_001576"
     CDS             7149..7982
                     /locus_tag="VU534_001576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEU1514138.1"
                     /translation="MKQDERKALIGKYILLILGSVLILVPLLATLFSSFKPTKDIVDN
                     FFGFPTNFTWDNFSRLLADGIGGYYWNSVVITVLSLLAVMIFIPMAAYSIARNMSKRK
                     AFTIMYTLLILGIFVPFQVIMIPITVMMSKLGLANTFGLILLYLTYAIPQTLFLYVGY
                     IKISIPESLDEAAEIDGANQFTTYFRIIFPMMKPMHATTMIINALWFWNDFMLPLLVL
                     NRDSKMWTLPLFQYNYAGQYFNDYGPSFASYVVGIISITIVYLFFQRHIISGMSNGAV
                     K"
     gene            7983..8063
                     /locus_tag="VU534_001577"
                     /pseudo
     CDS             7983..8063
                     /locus_tag="VU534_001577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            8340..9782
                     /gene="gtfA"
                     /locus_tag="VU534_001578"
     CDS             8340..9782
                     /gene="gtfA"
                     /locus_tag="VU534_001578"
                     /EC_number="2.4.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001122330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose phosphorylase"
                     /protein_id="HEU1514139.1"
                     /translation="MPIQNKTMLITYSDSLGNNLKDLYDNLEEHFGDAIGGVHLLPFF
                     PSTGDRGFAPVDYDEVDSAFGDWEDVKRLGEKYYLMFDFMINHISRQSKYYKDYQEKH
                     EASEFKALFLNWDKFWPENRPTQSDVDLIYKRKDRAPKQEIVFEDGSVEHLWNTFGEE
                     QIDLDVTKEVTMEFIRKTIQHLASNGCDLIRLDAFAYAVKKLDTNDFFVEPDIWDLLD
                     KVRDIAAEYGTELLPEIHEHYSIQFKIADHDYYVYDFALPMVTLYTLYSSRTERLAKW
                     LKMSPMKQFTTLDTHDGIGVVDVKDILTDEEIDYASNELYKVGANVKRKYSSAEYNNL
                     DIYQINSTYYSALGDDDVKYFLARLIQAFAPGIPQIYYVGLLAGKNDLKLLEETKEGR
                     NINRHYYSNEEIAKEVQRPVVKALLNLFSFRNRSEAFDLEGTTEIETPTAHSIVIKRQ
                     NKDKSVTAVVEIDLQNQTYRVIENGVEVSF"
     gene            9920..11113
                     /locus_tag="VU534_001579"
     CDS             9920..11113
                     /locus_tag="VU534_001579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008293041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HEU1514140.1"
                     /translation="MKSIGFIEKLKGLSSKELILLGIILSIFLPFYLFVVVLCLYIIS
                     LIFTGDMKSILQKMGEHPMLLLFLSYSTVISILAQNWMGLVASVGMFLFTIFFLHYQS
                     ILSHKFFRLILQFVLFGSVLSAAFASLEHFQIVKKFNYAFLSPNMQVWHQNRAEVTFF
                     NPNYYGIICCFCIMIAFYLFTTTKLNWLKVFCVIAGFVNLFGLNFTQNRTAFPAIIAG
                     AIIYLFTTIKNWKAFWLSIGVFAIGLSFLFSSDLGVRMGTLDSSMEERISIWDAGMAL
                     FKQNPFWGEGPLTYMNSYPRIHAPYHEHAHSLYIDTILSYGIVGTILLVLSSVAPVRL
                     MMDMSQESGKRPIIGLYLSFLTVVAVHGIFDLALFWIQSGFIFLLVMCSIPLEHRMLV
                     SDMTD"
     gene            11798..13777
                     /locus_tag="VU534_001580"
     CDS             11798..13777
                     /locus_tag="VU534_001580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000742236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEU1514141.1"
                     /translation="MKKNRVFATAGLVLLAAGVLAACSSSKSSDSSAPKAYGYVYTAD
                     PETLDYLISSKNSTTVVTSNGIDGLFTNDNYGNLAPAVAEDWEVSKDGLTYTYKIRKG
                     VKWFTSDGEEYAEVTAKDFVNGLKHAADKKSEAMYLAENSVKGLADYLSGTSTDFSTV
                     GVKAVDDYTLQYTLNQPEPFWNSKLTYSIFWPLNEEFETSKGSDFAKPTDPTSLLYNG
                     PFLLKGLTAKSSVEFVKNEQYWDKENVHLDTINLAYYDGSDQESLERNFTSGAYSYAR
                     LYPTSSNYSKVAEEYKDNIYYTQSGSGIAGLGVNIDRQSYNYTSKTTDSEKVATKKAL
                     LNKDFRQALNFALDRSAYSAQINGKDGAALAVRNLFVKPDFVSAGEKTFGDLVAAQLP
                     AYGDEWKGVNLADGQDGLFNADKAKAEFAKAKKALEADGVQFPIHLDVPVDQASKNYI
                     SRIQSFKQSVETVLGVENVVVDIQQMTSDEFLNITYYAANASSEDWDVSGGVSWGPDY
                     QDPSTYLDILKTTSSETTKTYLGFDNPNSPSVVQVGLKEYDKLVDEAARETSDLNVRY
                     EKYAAAQAWLTDSSLFIPAMASSGAAPVLSRIVPFTGASAQTGSKGSDVYFKYLKLQD
                     KVVTKEEYEKAREKWLKEKAESNEKAQKELASHVK"
     gene            13844..15340
                     /locus_tag="VU534_001581"
     CDS             13844..15340
                     /locus_tag="VU534_001581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU1514142.1"
                     /translation="MKKYIFMRVLRSLVSIFLVTTLTYTIIYTLVPRKLIFKQDPNYN
                     KIATTADKRDNYENTVFERMGYIEYYDTKELQEKASSMDSSVTVEANATNKAIYEKYI
                     NQLGHGWTLGEFTESGQFYATREIPIFERVFHFYANLIDIDHTNKIQDPENPDLKRYL
                     RFENDPAIGWSLVGSGTKHKYLLYFNSQFPFVHQNFVNLNLGDSYPTYANTPVLQVIT
                     QGQGQTKTAQVQFPTGKKTSSVNIYSRTYKSPSQADSREVASYGKDDPYTATESNYQY
                     PSMIVSSAITGLIGLVLAYALAVPLGSAMARFKNTWIDSLSTGALTFLLALPTIALVY
                     IVRLIGSSIALPDSFPILGAGDWRSYVLPAVILGLLGAPGTAIWIRRYMIDLQSQDFV
                     RFARAKGLSEKEISNKHIFKNAMVPLVSGIPAAIIGVIGGATLTETVFAFPGMGKMLI
                     DSVKASNNSMVVGLVFIFTCISIFSRLLGDIWMTIIDPRIKLTEKGGK"
     gene            15340..16266
                     /locus_tag="VU534_001582"
     CDS             15340..16266
                     /locus_tag="VU534_001582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU1514143.1"
                     /translation="MSTIDKEKFQFVKRDDFASETIDAPAYSYWKSVFKQFMKKKSTV
                     VMLGILVAIILISFIYPMFSKFDFNDVSKVNDFSVRYIKPNAEHWFGTDSNGKSLFDG
                     VWFGARNSILISVIATVINLVIGVFVGGIWGISKSVDRVMMEVYNVISNIPPLLIVIV
                     LTYSIGAGFWNLIFAMSVTTWIGIAFMIRVQILRYRDLEYNLASRTLGTPTLKIVAKN
                     IMPQLVSVIVTTMTQMLPSFISYEAFLSFFGLGLPITVPSLGRLISDYSQNVTTNAYL
                     FWIPLTTLVLVSLSLFVVGQNLADASDPRTHR"
     gene            16275..17342
                     /locus_tag="VU534_001583"
     CDS             16275..17342
                     /locus_tag="VU534_001583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU1514144.1"
                     /translation="MTKEKNVILTARDIVVEFDVRDKVLTAIRGVSLELVEGEVLALV
                     GESGSGKSVLTKTFTGMLEENGRIAQGSIDYRGQDLTALSSHKDWEQIRGAKIATIFQ
                     DPMTSLDPIKTIGSQITEVIVKHQGKTAKEAKELAIDYMNKVGIPDADRRFNEYPFQY
                     SGGMRQRIVIAIALACRPDVLICDEPTTALDVTIQAQIIDLLKSLQNEYHFTTIFITH
                     DLGVVASIADKVAVMYAGEIVEYGTVEEVFYDPRHPYTWSLLSSLPQLADDKGDLYSI
                     PGTPPSLYTDLKGDAFALRSDYAMQIDFEQKAPQFSVSETHWAKTWLLHEDAPKVEKP
                     AVIANLHDKIREKMGFAHLAD"
     gene            17353..18279
                     /locus_tag="VU534_001584"
     CDS             17353..18279
                     /locus_tag="VU534_001584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU1514145.1"
                     /translation="MSEKLVEIKDLEISFGEGSKKFVAVKNANFFINKGETFSLVGES
                     GSGKTTIGRAIIGLNDTSNGDIIFDGQKINGKKSREQAAELIRRIQMIFQDPAASLNE
                     RATVDYIISEGLYNHRLFKDEEERKEKVQNIIREVGLLAEHLTRYPHEFSGGQRQRIG
                     IARALVMQPDFVIADEPISALDVSVRAQVLNLLKKFQKELGLTYLFIAHDLSVVRFIS
                     DRIAVIYKGVIVEVAETEELFNNPIHPYTQALLSAVPIPDPILERKKVLKVYDPSQHD
                     YETDKPSMVEIRPGHYVWANQAELARYQKGLN"
     gene            complement(18354..>18755)
                     /locus_tag="VU534_001585"
     CDS             complement(18354..>18755)
                     /locus_tag="VU534_001585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001249392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU1514146.1"
                     /translation="RPTFRMHLTNKEILDKILSYSEDLKHHYQIYQLLLFHFQNKDPE
                     KFFGLIEDNLKQGHPLFQTVFKTFLKDKEKIINALQLHYSNAKLEATNNLIKLIKRNA
                     FGFRNFENFKKRIFIALNIKKERTKFVLSRA"
BASE COUNT         5448 a         3358 c         4001 g         5948 t
ORIGIN      
        1 gcggtgtagc tcagctggct agagcgtccg gttcataccc gggaggtcgg gggttcgatc
       61 cccttcgccg ctataatgat cttgtcggac ctttagctca gctggttaga gctctcggct
      121 cataaccgag tggtcgtagg ttcaagtcct acaaggtcca tttgaatatt ggaggattac
      181 ccaagtccgg ctgaagggaa cggtcttgaa aaccgtcagg cgtgtaaaag cgtgcgtggg
      241 ttcgaatccc acatcctcct tttatattat taacgcggga tggagcagct cggtagctcg
      301 tcgggctcat aacccgaagg tcgtaggttc aaatcctgct cccgcaataa ggctcggtag
      361 ctcagttggt agagcaatgg attgaagctc catgtgtcgg cggttcgatt ccgtctcgcg
      421 ccattttatt gatagtattt atgcgggtgt agtttagtgg taaaactaca gccttccaag
      481 ctgttgtcgc gagttcgatt ctcgtcaccc gctttgaact ttgttcaaat taccaagttt
      541 tttaacttgg gcgcgtagct caggtggtta gagcgcacgc ctgataagcg tgaggtcggt
      601 ggttcgagtc cactcgtgcc cattaattgg agaattactc aagaggctga agaggacggt
      661 ttgctaaatc gttaggtcgg gtaactggcg caagggttcg aatcccttat tctccgtttt
      721 aatgagagtc tgtaactctc ttttttattt ttagagccaa taaaacttca gatccgtaaa
      781 acttaattga attactaatc tgaagttatt tttatatcgt ttatattata attgtgttat
      841 tttacttcca actattgaga gaaatttcgc cactatttag ccagatttct tttccgttat
      901 cacattgaac taaaagtttt ccattttctg agatgtcttt agcaagtccc ttgtagtctt
      961 tttgctctag tgtgaaagtg acttcttttc ctagaatgaa tgactgtttt ttgtataggt
     1021 ataatagctc ttctgctggt gtttcgaaga aagcacgcca gatttctatg atcaattcat
     1081 tccttgttat aggagctgta gctttaaata agctggcagc tttttctttt aattcctgag
     1141 ggaagtcttt aatagtgaaa ttgataccta ctccaataat gatatctgtg actaagccag
     1201 tttctacaga ggtcattgct tcagtaagga ttcctccaat tttatgattg tttagataga
     1261 tatcattgac ccattttatg tcgacatcta ttaaagttag gttcttaatg gctttgtaga
     1321 cagctccagc tacaagtagt gtgtaggatg gtaatttgtc ataggggaga tttggtttaa
     1381 gatggagtgt catataaata ccaccttgtg gtgagtagaa ggaacgttga aaacggcctc
     1441 ggcctgctgt ttgataggaa gctagataga gggtatttgc ttcatggcct aaatcaattg
     1501 cttcttttgc atctagttgt gttgattttg tttcgggttt aaagctgact ttaattggaa
     1561 gattttcttc tagaatctct ggaagaataa ggtcaccatt catcagttta tatcctctat
     1621 ttttgatact atcaatttca atgccttctt gttctagtcg cttgatggct ttccaaattg
     1681 ctgttcggct tagggatagt ttttctgcga ttttttctcc gctgatatag tcggtttctt
     1741 tagataggat ttggtagaca gcttggtagg atttcataat gttgcctttc ttactagttg
     1801 gtattgagag tattcttttc ttgtatgact tggagtctga ttaaagtatt gtttataagc
     1861 tttcgaaaaa tggagtggat ctgaaaaacc taccgagtat gcaattacct tgatggactc
     1921 ttgggtattt tcgagaagtt gtctagctcg gtgcattcga acgtagagta ggtattcttt
     1981 gggtgataag gtattaaatt ctttgaatac gcttgataag tagcttctgt gaacggatag
     2041 ttcttttgct aaatcttgaa ttgtaagtga ttgaggatag tggctatcaa ttaatcgttt
     2101 gcattcaaga tagagttggt gggttgatga aatattcttt tttttctgat tgggagcaat
     2161 agttcccaga tgaaacatca gttcatgaag ttgtcccatg atatggagtt gagctaattc
     2221 acttgatttt gtaatctgag cgaagcggac aatgtctgag atgagttttg cagtagtctg
     2281 ggtatgacaa gtttcagatt ggatgagata ggattgatca gaaatttggg aaagagcaaa
     2341 ataatcaggg gctttccctc cagtgattcc taaccagtag taggcccaag gttctttact
     2401 atctgcttga taaaaggtta gttcctctgg ttttaataga aagaaatctc cttcttttaa
     2461 atcaacaatt ttacccttgt aatgaaattt tccttgtcct ttagtaatgt aatgtagaac
     2521 gtatgtatca cgaatggctg gaccaaaaga gtaattaggt gtgcattcct catatccata
     2581 aaagcttagg gcaaggtcga ttgttccagt ctggtattct gaaaaaacta acatgtgcta
     2641 cctcctacct aacattttac catattcttg agacattttt ctattttgga aagcgatttc
     2701 aggtgataaa atataatcaa taaagtgatg aggtgaagta aatgggagtt aggatagaga
     2761 ataatctatt ttatgttgag agtaaaaatc taagtttgat tattgaaaat cgaaatggct
     2821 acttactttt gaaacattta ggaaagacta ttaagaacta taaaggttcc aatagtgttt
     2881 atgaacgaga ccatgccttt tcaggaaatc caacggctac taatcgaacc tttagtttag
     2941 atactcagcg acagattttt ggacaacatg gcttaggaga ttttaggaaa ccaaccatac
     3001 aggttcagca tagtgtaact gaagtaacag actttcgatt tgtagaagca aagattttaa
     3061 aaggtcagaa tggtccacag ggcttacctt ctccacatag catggacgat acagagactc
     3121 ttgtcttaat gttagaagat tctaaggctc aacttagtct gactttgtat tatactactt
     3181 ttaataatga tgcgactatt gctagctaca gtaaattaga taataatagt aatcaggaag
     3241 ttgtcatcca taaagatttt tcttttatgg ctgattttcc agctgcagat tacgaaatag
     3301 taactctgca gggtgcttat gctcgtgaaa agactgttag acgtcaacag gtagaacaag
     3361 gaatcttttc gattagttca aaccgaggtg cttctggtca tgctcaaaca ccagctcttc
     3421 tactatgcga acaaggagtc acagaggatg ctgggaatgt gtttgctatt caactaatgt
     3481 atagtggcaa ctttgaagct tttgttcaaa aaaatcaatt gaatgaagtt cgggtggcta
     3541 ttggcattaa tccagaaaac ttttcttgga agttagctcc tgaggaatac tttgaaacac
     3601 cggtagcttt agtgactcat tcagatcagg gattaactgg tattagtcat gaaagtcaga
     3661 attttgtact gaagcacatt atgctaagtg aattttctaa aaaagaacgt ccaattctaa
     3721 tcaataactg ggaagctact tactttgact ttcagagaga aaaactgtta gagttagcag
     3781 atgaagctaa gaaagttggc attgaacttt ttgtattaga tgatggttgg tttggcaatc
     3841 gttttgatga taatcgtgct ttaggtgatt gggttgttaa tgaggaaaaa ctgggtggaa
     3901 gtctagaaag tctgatttca gctatccatg aaagaggttt gcagtttgga ctttggttag
     3961 aacccgaaat gatttctgta gatagtgatt tgtatcgtca acatcctgac tgggctattc
     4021 aggttcctgg ctatgagcat acttattctc ggaatcaatt agtacttaat cttgccaatc
     4081 ctcaggtagt agaatacttg aaaagtgtct tagatcaact cctattttat catgatattg
     4141 attacattaa atgggatatg aaccgcaata tcactaagct agggaatgga ttaacttatc
     4201 tagagacaca gatgcaatct catcagtaca tgctggggct ttatgaactc gtttcttatc
     4261 tgacagagaa gcacagccat attctctttg agtcctgctc tggtggtggt ggacgaaatg
     4321 atcttggtat gatgcgctat ttcccacaag tctgggctag tgataatact gatgccattg
     4381 cacgtttacc aattcaatac ggttcatcct atctctatcc aaccatttct atgggggctc
     4441 atgtgtcagc agtaccgaat catcagatgg gacgaatgac accattagaa acacgtggcc
     4501 ttgtagcaat gatgggaaat ttgggctatg aacttgattt gacaaattta tcagatgaag
     4561 agaaagctac gattgctaat caggtgaact tgtataaaga attacgacca gtagttcagt
     4621 taggacagca gtatagacta attaatcctg atactgtatc caatgaagca gctgtacaat
     4681 ttaattacgg aaatcaaacg attgtaacct acgttcgcgt tttatctgtt gtagagacca
     4741 tggaaacaac tttaaaatta aaagatttgg atgaagaggg actatataaa ttacaggaaa
     4801 atggcgaagt ttactcaggt gcagaactaa tgtatgcggg cttaactgtt atcttatccc
     4861 aaggagattt tttgagtaga cagtatattt ttagaaaact atgatatgta ctgaccccaa
     4921 aagttagatt tattctgtct aacttttggg gtgcagttca ataagggtgt ataaatttat
     4981 aaaggaggct ttctaatgga atggtataaa aaaatcggac ttcttgcaac tacaggttta
     5041 gctttgtttg ggctcggcgc ttgctccaac tatggtaaat ctgcggatgg cacagtgacc
     5101 atcgagtatt tcaaccagaa aaaagaaatg accaaaacct tggaagaaat cactcgtgat
     5161 tttgagaagg aaaaccctaa gatcaaggtc aaagtcgtca atgtaccaaa tgctggtgaa
     5221 gtattgaaga cacgcgttct cgcaggagat gtgcctgatg tggtcaatat ttacccacag
     5281 tccatcgaac tgcaagaatg ggcaaaagca ggtgtttttg aagatttgag caacaaagac
     5341 tacctgaaac gcgtgaaaaa tggctacgct gaaaaatatg ctgtaaacga aaaagtttac
     5401 aacgttcctt ttacagctaa tgcttatgga atttactaca acaaagataa attcgaagaa
     5461 ctgggcttga aggttcctga aacctgggat gaatttgaac agttagtcaa agatatcgtt
     5521 gctaaaggac aaacaccatt tggaattgca ggtgcagatg cttggacact caatggttac
     5581 aatcaattag cctttgcgac agcaacaggt ggaggaaaag aagcaaatca ataccttcgt
     5641 tattctcaac caaatgccat taaattgtcg gatccgatta tgaaagatga tatcaaggtc
     5701 atggacatcc ttcgcatcaa tggatctaag caaaagaact gggaaggtgc tggctatacc
     5761 gatgttatcg gagccttcgc acgtggggat gtcctcatga caccaaatgg gtcttgggcg
     5821 atcacagcga ttaatgaaca aaaaccgaac tttaagattg ggaccttcat gattccagga
     5881 aaagaaaaag gacaaagctt aaccgttggt gcgggagact tggcatggtc tatctcagcc
     5941 accaccaaac atccaaaaga agccaatgcc tttgtggaat atatgacccg tccagaagtc
     6001 atgcaaaaat actacgatgt ggacggatct ccaacagcga tcgaaggggt caaacaagca
     6061 ggagaagatt caccgcttgc tggtatgacc gaatatgcct ttacggatcg tcacttggtc
     6121 tggttgcaac aatactggac cagtgaagca gacttccata ccttgaccat gaactatgtc
     6181 ttgaccggtg ataaacaagg catggtcaat gatttgaatg ccttctttaa cccgatgaaa
     6241 gcggatgtgg attaggagta gagagactat gaaaaaagta ttacaaaaat attgggcatg
     6301 ggcttttgtg gtcatccccc tcttgttaca agcaattttc ttctatgtgc cgatgtttca
     6361 aggagccttt tacagtttta ccaactggac aggattgact tataactaca aatttgttgg
     6421 cttaaacaac tttaagctcc tcttcatgga tccaaaattc atgaatgcga ttggctttac
     6481 cgcaatcatt gcgattgcca tggtggttgg tgagattgca ctcgggatct tcattgcgcg
     6541 tgtcttgaat tctaaaatca aaggccaaac cttcttccgt gcttggttct tcttcccagc
     6601 tgttttatct ggtttgacag tggctttgat cttcaagcaa gtcttcaact acggtcttcc
     6661 agcgattgga aatgcccttc atattgaatt tttccaaacc agtcttttag ggactaagtg
     6721 gggagcaatc tttgcggctg tctttgtcct tctttggcaa ggggtggcta tgcccatcat
     6781 catcttccta gctggtttgc aatctattcc aactgagatt acagaggcag caaggattga
     6841 tggtgcgact agcaagcaag ttttctggaa cattgaattg ccttacttgc taccaagtgt
     6901 ctctatggtc tttatcctag ccctaaaagg tgggctgact gcctttgacc aagtctttgc
     6961 catgaccggt ggtggtccaa acaatgccac aacctcactt gggctcttgg tttataacta
     7021 tgcctttaaa aacaaccaat tcggttatgc caatgccatt gccgtaatct tgttcttctt
     7081 aattgtagtg atttcgatca tccaattgag agtatctaag aaatttgaaa tttaagagga
     7141 gaagcatgat gaaacaagat gaaagaaaag ccctgattgg caaatacatt ctattgattc
     7201 taggatcggt tctgatttta gtgccgctcc ttgctaccct ctttagttcc ttcaaaccca
     7261 ctaaggatat tgtagataat ttctttggct ttccaaccaa cttcacatgg gacaacttta
     7321 gccgtctctt agctgatggg attggaggct attattggaa ctctgtcgtc atcactgtct
     7381 tgtctttact tgcagtaatg atctttatcc ctatggcagc ctactccatc gctcgcaata
     7441 tgagtaaaag aaaagccttt accatcatgt ataccctctt aatcctcgga atcttcgtac
     7501 ctttccaagt catcatgatt ccgattacgg ttatgatgag taaactcggt ttggctaata
     7561 cctttggttt gatcttgctc tacttgacct atgcgattcc acagaccctc tttctctatg
     7621 ttggctatat caaaatctcg attccagaaa gtctggatga agcagcagag atcgatgggg
     7681 ctaatcaatt tacaacctat ttccgcatca tcttcccaat gatgaaaccg atgcatgcga
     7741 caaccatgat catcaatgcc ctttggttct ggaatgactt catgttgcca ctccttgtct
     7801 tgaaccggga ttccaaaatg tggactctgc ctttgttcca atacaactac gcaggccaat
     7861 atttcaacga ctacggacca agctttgcct cttacgtggt cggcattatc agtatcacca
     7921 ttgtctatct cttcttccaa cgccatatca tttcaggaat gagcaacggg gcagtgaagt
     7981 aatactcaat gaaaatcaaa gagcaaacta ggaagctagc cgcaggttgc tcaaaacact
     8041 gttttgaggt tgtggatgaa actgacgaag tcagtaacca tacctacggc aaggtgaagc
     8101 tgacgtggtt tgaagagatt ttcgaagagt ataagaagag ctcatggaat ctatagtctt
     8161 tgacacagag gaagagttta gcttgttgat aattctatgc agaaaacaag aaagtagtac
     8221 tttgtttatc acagtctata ttagtacgag tttgatgata aatagagatt taaaatgaat
     8281 tttatttatg aagccagatc atatgagact tggcttcaat tagaaaaagg agagtaatga
     8341 tgccaattca aaataaaacc atgttgatta cctattctga tagccttgga aataatctta
     8401 aagacttata tgataatttg gaagagcatt ttggagatgc tattggagga gttcaccttt
     8461 taccattttt cccatcaaca ggtgatcgtg gatttgcgcc agttgactac gacgaagtgg
     8521 actcagcttt tggtgattgg gaggatgtga agcgtttagg tgagaaatat tatcttatgt
     8581 ttgattttat gattaatcat atttctcgtc aatccaagta ttataaggac tatcaagaaa
     8641 aacatgaagc cagtgaattt aaagctctct ttttaaactg ggataagttt tggccagaaa
     8701 accgtccgac acagtctgat gtagatttaa tttacaagcg taaggatcgt gcaccaaagc
     8761 aagagattgt gtttgaagat ggttcagtgg aacatttgtg gaataccttt ggtgaggagc
     8821 agattgatct tgatgtgacc aaagaagtaa ctatggaatt tatccgtaag accattcagc
     8881 acttggcaag taatgggtgt gatttgattc gtctagatgc ctttgcttat gcagtgaaga
     8941 aattggatac taatgatttc tttgtggaac cagatatttg ggatttattg gacaaagttc
     9001 gagatatcgc tgctgagtat gggacagagc ttttacctga gattcatgaa cactattcga
     9061 ttcagtttaa aatagcagac catgattact atgtttatga ttttgctctt ccaatggtga
     9121 cactttatac tctttacagt tccagaacag agcgtttggc taagtggtta aagatgagcc
     9181 cgatgaagca atttacgacg ctagataccc atgatgggat tggagtagta gatgtcaagg
     9241 atatcctgac cgatgaggag attgactatg cttcaaatga actctataag gttggagcca
     9301 atgtcaaacg taagtactct agtgccgagt ataacaactt agatatctac caaatcaatt
     9361 caacctacta ttcagcgctt ggagatgatg atgtcaagta ttttctcgct cgtctaattc
     9421 aagcttttgc cccaggtatt cctcagattt actatgtggg tctattagca ggcaagaatg
     9481 acttgaaatt attagaagaa actaaagaag gtcgaaatat taatcgtcat tactatagca
     9541 acgaggaaat agcaaaagaa gtgcaacgac ctgttgtgaa ggcccttctc aatctatttt
     9601 ctttccgtaa ccgttcagaa gcctttgatc tagaagggac tactgagata gagacaccaa
     9661 cagctcacag cattgtaatc aaacgtcaaa ataaagataa gtccgtaaca gcagtagtag
     9721 aaattgattt gcaaaatcag acttatcggg taattgagaa tggagttgaa gtatcatttt
     9781 gaagccttga tatggtggat aaaatagggt ttttattttg gaaaacgttt cctttgtttt
     9841 caaattgcta aaaaagtggt acaatatagg atagcttact attatctgaa tcagctgatt
     9901 tggagagaaa ggattcattt tgaaatcaat aggctttatt gaaaagctga aggggttgtc
     9961 tagtaaagag ctgattttat tgggaattat cctgagtatc tttttaccct tttatctttt
    10021 tgtagttgta ctctgtttat atattatcag tttgattttt acaggagaca tgaaaagtat
    10081 tcttcagaaa atgggggagc atccgatgct gcttcttttt cttagctata gtactgttat
    10141 atccattctt gcacaaaatt ggatgggtct tgtggcttca gtaggaatgt ttctatttac
    10201 tattttcttt ttgcactatc agtcgatttt atcccataaa ttctttcgat tgattttgca
    10261 gtttgtcttg tttggtagtg tcttgtcagc tgcttttgcc agtttagaac atttccaaat
    10321 tgtgaagaaa tttaactatg cttttctttc acccaatatg caggtgtggc atcagaaccg
    10381 ggcagaagtg accttcttta atcctaatta ttatggaatt atttgttgtt tctgtattat
    10441 gattgctttc tatctgttta caacgaccaa gttgaattgg ttgaaagtat tctgtgtgat
    10501 tgcaggcttt gttaatctct ttggtttgaa ctttactcaa aatcgaactg cctttcctgc
    10561 tattatcgct ggagcaatta tctatctctt tacgactatt aaaaactgga aggccttttg
    10621 gcttagtatt ggggtcttcg cgattggttt gagtttcctc ttttctagtg atttgggagt
    10681 tcgaatgggt actttagact cttctatgga agaacgcatt tctatctggg atgctgggat
    10741 ggccttgttt aagcaaaatc ctttttgggg tgaagggcca ttgacctata tgaactctta
    10801 tcctcggata catgctcctt atcatgaaca tgcccacagt ctttatattg atacgattct
    10861 gagttacgga attgtgggga ctattttatt agttttgtct tctgttgctc ctgttcgctt
    10921 gatgatggat atgagtcagg agtcggggaa acgtccgatt atcggccttt atctatcttt
    10981 ccttacagtg gttgctgtgc acggaatttt tgacttggct ctcttctgga ttcagtcagg
    11041 ctttattttc ttgctagtta tgtgcagtat tccattggag catcgaatgt tggtatcgga
    11101 catgacggat taagttttat aagtttgaaa tcttctacct tgggtaggag attttttata
    11161 cgatgggcat gtcgtgcatc tgaggtgtaa gtcctctgta gggctccact accggtgaat
    11221 acaatagcgc tccccaagcc tgactatcgt gaggtagcgg attaaaatgg tctggggata
    11281 gatcgtttta agtctgacgc aggaaataag aattgtcaga gaaagcaata gtgaaatcgt
    11341 aggctatgaa tagaaacgtg atagcgagga gcatatagtg gataaggtag cgagaaattt
    11401 taaagtataa aagatagtct taatctatat atgtaaatca caaaagtaat tgaattcggg
    11461 ataaggttgg tgtgaaaaga catagtaaac tgaatcttga atactagaat gatacttcta
    11521 caatattgtt ataatttaat ttgaattcca aaatcacatt gttccgtccg tatttcattt
    11581 tactgtatgt cttcctaaac tccaaagttt ctgcgtcaaa tttcctattt tcactgtagt
    11641 ctttgacact tcgaacgaca atttgaatca tatattcaaa aaaaatgaaa aatttgtgcc
    11701 aacaagccta aatattctga aaatttgttt gatttttaat ggataatgtg atataatggt
    11761 tgtcaatcta taattcacat aaacagagga gtagaaaatg aaaaaaaatc gtgtatttgc
    11821 tacagcaggt cttgttttat tagcagcagg tgtacttgca gcatgcagtt cttcaaaatc
    11881 atctgattca tcagccccta aagcttatgg ctatgtttat acagcagacc cagaaacctt
    11941 ggactacctg atttcaagta aaaatagtac aacagtagtg acttcaaatg ggattgatgg
    12001 tttattcact aacgataatt acggtaatct tgctcctgca gttgcagagg attgggaagt
    12061 ctctaaggat ggtttgacct acacttataa gattcgtaaa ggggttaaat ggtttacctc
    12121 tgatggagaa gaatatgcag aggtgacggc taaagatttc gtgaacggtt taaaacacgc
    12181 agcagataaa aaatcagaag ctatgtattt agctgaaaat tcggttaaag gcttggcaga
    12241 ttatctatca ggaacttcaa cagatttttc aacagttggt gtcaaggcgg ttgatgatta
    12301 tacgttacaa tacactttga accagcctga accgttctgg aactctaagt tgacctattc
    12361 tattttctgg cctctgaatg aagaattcga aacatcaaaa ggaagcgatt ttgctaaacc
    12421 aacagatccg acatccttgc tttataatgg tccattcttg ttgaaagggt tgactgcaaa
    12481 atcttctgta gagtttgtaa aaaatgagca atattgggat aaagaaaatg tccacctaga
    12541 tactatcaat ctagcttact atgatggatc agatcaggag tcgctagagc gtaacttcac
    12601 tagtggagct tatagttatg cccgtcttta ccctaccagc tccaactatt ctaaggttgc
    12661 agaagaatac aaggacaata tctattacac acaatcaggc tctgggattg ctggtctggg
    12721 tgtgaatatt gatcgccaaa gttacaacta tacttctaaa actacagatt cagagaaagt
    12781 agctactaag aaggcattgc ttaacaaaga tttccgtcaa gccttgaatt ttgctcttga
    12841 tcgctcagct tactcagctc aaatcaatgg taaagatgga gcagctttag cagttcgtaa
    12901 tttatttgta aaaccagact ttgtttcagc tggtgagaag acctttggtg atttagtcgc
    12961 tgctcaactt cctgcttatg gtgatgagtg gaaaggtgtg aatttagctg atgggcagga
    13021 tggtttattc aatgctgaca aggccaaggc agagtttgcg aaagctaaga aagctttaga
    13081 agcagacggc gttcagtttc ctattcatct ggacgttcca gtagaccaag catcaaaaaa
    13141 ctacatatct cgtattcagt cctttaaaca atctgtagaa acagttcttg gtgttgaaaa
    13201 tgtcgttgtt gatattcaac aaatgacaag tgatgaattc cttaatatta cttactatgc
    13261 tgccaatgct tcatctgagg attgggatgt atcaggagga gtttcatggg ggccagacta
    13321 tcaagaccca tctacttacc tggatatttt aaaaacaact agcagtgaaa ctacaaaaac
    13381 atatttagga tttgataatc caaatagccc ttcagtagtt caagttggtt tgaaagaata
    13441 cgataaatta gttgatgaag ctgccagaga gacaagcgac ttgaatgtcc gttatgaaaa
    13501 atatgcagcg gctcaagcat ggttgacaga tagttcactc tttattcctg ctatggcttc
    13561 ttctggtgca gcaccagtgc tttcacgaat tgttccattt actggagctt ctgcgcaaac
    13621 aggctctaag gggtcagatg tttacttcaa atatttgaaa ttacaagata aagtggtgac
    13681 taaggaagag tatgaaaaag ctcgtgaaaa atggttgaaa gaaaaagctg aatcaaatga
    13741 gaaagctcaa aaagaattgg caagtcatgt gaagtaaata atttctaata gaactttctc
    13801 tccatgagga gaaggttctt ttgggatttt taaaggaaat aatatgaaaa aatatatttt
    13861 tatgcgtgtt ttgcggtcat tggtttcgat tttcttagta acgactttga cctacacgat
    13921 tatctatacc ttggttcctc gaaaattgat tttcaagcag gatcctaact ataataaaat
    13981 tgcgacaacg gctgataaac gtgataacta tgaaaatact gtgtttgagc gtatgggcta
    14041 cattgagtat tacgatacta aagagttgca agaaaaggca agtagcatgg attcttctgt
    14101 aacagtagaa gcaaatgcga ccaataaagc tatttatgaa aagtacatca atcaattagg
    14161 tcatggttgg actttgggag aatttactga aagtggtcaa ttctatgcta ctcgtgaaat
    14221 tccaattttt gaacgtgttt ttcacttcta tgctaacttg attgacattg accatacaaa
    14281 taaaatccaa gaccctgaaa atccagactt gaaacgctac cttcgttttg aaaatgatcc
    14341 agctatcgga tggtcattgg tcggttcagg aactaaacat aaatatctct tgtactttaa
    14401 cagtcagttc ccatttgttc atcaaaactt tgtgaacttg aatttaggtg actcttaccc
    14461 aacctatgct aatacaccag ttcttcaggt tattactcaa ggtcaaggac aaaccaaaac
    14521 tgcccaagtt cagttcccaa caggtaagaa aacgtcttct gtaaatattt actcaagaac
    14581 ctacaagtca cctagtcagg ctgactctcg tgaagtagct agctatggga aagatgatcc
    14641 ttatacagcg actgaaagta attaccaata tccatctatg attgtcagct ctgctattac
    14701 tggtttgatt ggtttggttc ttgcctatgc tcttgccgtg ccacttggtt cagccatggc
    14761 tcgtttcaag aacacttgga ttgatagcct ctcaacaggg gctttgacct tcttgcttgc
    14821 tcttccaacg attgccttgg tttacatcgt tcgattgatt ggatcatcta ttgcccttcc
    14881 agattcattc cctatcttgg gagctggaga ttggcgttct tacgttttac cagcagtcat
    14941 ccttggtttg ttgggtgctc ctggtacagc catttggatt cgtcgttaca tgattgactt
    15001 gcaatctcaa gactttgttc gtttcgctcg tgcaaaaggt ttgtctgaaa aagaaatttc
    15061 aaacaaacac atctttaaaa atgccatggt tccgctggtt tcaggaattc ctgctgccat
    15121 tattggggtt atcggtggtg caacccttac tgaaacagtc ttcgccttcc caggtatggg
    15181 taaaatgttg attgactctg taaaagcatc taataactct atggtcgttg gtcttgtctt
    15241 catctttaca tgtatttcta tcttctcacg tcttttggga gatatttgga tgactattat
    15301 tgacccacgt attaaattga ctgagaaagg aggcaaataa tgtctacaat cgataaagaa
    15361 aaatttcagt ttgtaaaacg tgacgatttt gcctctgaaa ctattgatgc gccagcatat
    15421 tcttactgga aatcagtgtt taaacaattt atgaagaaaa aatcaactgt agtcatgttg
    15481 ggaatcttgg tagccatcat tttgataagt ttcatctacc caatgttttc taagtttgat
    15541 ttcaatgatg tcagcaaggt aaacgacttt agtgttcgtt atataaagcc aaatgcggag
    15601 cattggttcg gtactgacag taacggtaaa tcgctctttg acggtgtctg gttcggagct
    15661 cgtaactcca tcctcatttc tgtgattgcg acagtgatta acttggttat cggtgttttt
    15721 gtcggtggta tttggggtat ttcaaaatca gttgaccgtg tcatgatgga agtttacaac
    15781 gtcatctcaa acatcccacc tcttttgatt gttattgtct tgacttactc aatcggagct
    15841 ggattctgga atctgatttt tgccatgagc gtaacaacat ggattggtat tgccttcatg
    15901 atccgtgtgc aaatcttgcg ctatcgtgac ttggaataca acttggcgtc acgtactttg
    15961 ggaacaccaa ccttgaagat tgttgccaaa aatatcatgc ctcaattggt atctgttatt
    16021 gtgacaacca tgactcaaat gcttccaagc tttatctcat acgaagcctt cttgtctttc
    16081 ttcggtcttg gattaccgat tacagtgcca agtttgggtc gtttgatttc ggattattca
    16141 caaaacgtaa caaccaatgc ttacttgttc tggattccat tgacaaccct tgtcttggta
    16201 tccttgtccc ttttcgtagt tggtcaaaac ttagcggatg ctagtgatcc acgtacacat
    16261 agataggagt agaaatgaca aaagaaaaaa atgtaatttt gactgctcgc gatattgtcg
    16321 tggaatttga cgttcgtgac aaagtattga cagccattcg cggcgtttcc cttgaactag
    16381 tcgaaggaga agtattagcc ttggtaggtg agtcaggatc aggtaaatct gttttgacaa
    16441 agaccttcac aggtatgctc gaagaaaatg gtcgtattgc ccaaggtagt attgactacc
    16501 gtggtcagga cttgacagct ttatcttctc acaaggattg ggaacaaatt cgtggtgcta
    16561 agattgcgac tatcttccag gacccaatga ctagtttgga ccccattaaa acaattggta
    16621 gtcagattac agaagttatt gtaaaacacc aaggaaaaac agctaaagaa gcgaaagaat
    16681 tggccattga ctacatgaat aaggttggca ttccagacgc agatagacgt tttaatgaat
    16741 acccattcca atattctgga ggaatgcgtc aacgtatcgt tattgctatt gcccttgcct
    16801 gccgacctga tgtcttgatc tgtgatgagc caacaactgc cttggatgta actattcaag
    16861 ctcagattat tgatttgcta aaatctttac aaaacgagta tcatttcaca acaatcttta
    16921 ttacccacga ccttggtgtg gtggcaagta ttgcggataa ggtagcggtt atgtatgcag
    16981 gagaaatcgt tgagtatgga acggttgagg aagtcttcta tgaccctcgc catccatata
    17041 catggagtct cttgtctagc ttgcctcagc ttgctgatga taaaggggat ctttactcaa
    17101 tcccaggaac acctccgtca ctttatactg acctgaaagg ggatgctttt gccttgcgtt
    17161 ctgactacgc aatgcagatt gacttcgaac aaaaagctcc tcaattctca gtatcagaga
    17221 cacattgggc taaaacttgg cttcttcatg aggatgctcc gaaagtagaa aaaccagctg
    17281 tgattgcaaa tctccatgat aagatccgtg aaaaaatggg atttgcccat ctggctgact
    17341 aggaggaagg aaatgtctga aaaattagta gaaatcaaag atttagaaat ttccttcggt
    17401 gaaggaagta agaagtttgt cgcggttaaa aatgctaact tctttatcaa caagggagaa
    17461 actttctcgc ttgtaggtga gtccggtagt gggaaaacaa ctattggtcg tgctatcatc
    17521 ggtctaaatg atacaagtaa tggagatatc atttttgatg gtcaaaagat taatggtaag
    17581 aaatcgcgtg aacaagctgc ggaattgatt cgtcgaatcc agatgatttt ccaagaccct
    17641 gccgcaagtt tgaatgaacg tgcgactgtt gattatatta tttctgaagg tctttacaat
    17701 caccgtttat ttaaggatga agaagaacgt aaagagaaag ttcaaaatat tatccgtgaa
    17761 gtaggtcttc ttgctgagca cttgactcgt taccctcatg aattctcagg cggtcaacgt
    17821 caacgtatcg gtattgcccg tgccttggtc atgcaaccag actttgttat tgcagatgag
    17881 ccaatttcag ccttggacgt ttctgtacgt gcccaagtct tgaacttgct caaaaaattc
    17941 caaaaagagc tcggcctgac ctatctcttc atcgcccatg acttgtcggt tgttcgcttt
    18001 atttcagatc gtatcgcagt tatttacaag ggtgttattg tagaggttgc agaaacagaa
    18061 gaattgttta acaatccaat tcacccatat actcaagcct tgctttcagc ggtaccaatc
    18121 ccagatccaa tcttggaacg taagaaggtc ttgaaggttt acgatccaag tcaacacgac
    18181 tatgagactg ataagccatc tatggtagaa atccgtccag gtcactatgt ttgggcgaac
    18241 caagccgaat tggcacgtta tcaaaaagga ctaaactagt aatggtttta taatttccat
    18301 gtcaattttt atggaaatta ggctctttgt caactgtagt gggttgaagt cagctaagct
    18361 cgagaaagga caaatttcgt cctttctttt ttgatgttca aagcgataaa aatccgtttt
    18421 ttgaagtttt caaagtttcg aaaaccaaag gcattgcgct tgataagttt gatgagatta
    18481 ttggtcgctt ccagtttggc attagaatag tgtagttgaa gggcgttgat aatcttttct
    18541 ttatctttga gaaaggtttt aaagacagtc tgaaaaagag gatgaccctg cttcagattg
    18601 tcctcaatga gtccgaaaaa tttctcaggg tctttgttct gaaagtgaaa aagtaagagt
    18661 tgatagatct gatagtggtg tttcaagtct tctgaatagc ttaaaatctt gtcaagaatt
    18721 tctttatttg ttaagtgcat gcgaaaagta gggcg
//
LOCUS       DAVFER010000041        18140 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1105170250
            SAMEA2167659-rid19724873.denovo.041, whole genome shotgun sequence.
ACCESSION   DAVFER010000041 DAVFER010000000
VERSION     DAVFER010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2167659
            Sequence Read Archive: ERR388902
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18140)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18140)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928716.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928716.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 04:07:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,118
            CDSs (total)                      :: 2,073
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 120
            CDSs (without protein)            :: 120
            Pseudo Genes (ambiguous residues) :: 0 of 120
            Pseudo Genes (frameshifted)       :: 67 of 120
            Pseudo Genes (incomplete)         :: 47 of 120
            Pseudo Genes (internal stop)      :: 34 of 120
            Pseudo Genes (multiple problems)  :: 23 of 120
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18140
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2167659-rid19724873.denovo.041"
                     /strain="1105170250"
                     /db_xref="taxon:1313"
     gene            complement(<1..690)
                     /locus_tag="VU534_001586"
     CDS             complement(<1..690)
                     /locus_tag="VU534_001586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000362880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComD"
                     /protein_id="HEU1514147.1"
                     /translation="MDLLGFGTVIVHFLIISHSYRLICKGRINRKELYVFGAYTLLTE
                     IVLEFSFYLLYLDKIGIERFLFPLGLYSYFRWMKQYERDRGLFLSLLLSLLYESTHNF
                     LSVIFSSITGDNFVLQYHFPFFFVVTVLTYFVTLKIIYYFHLELAYFDKDYLYPFLKK
                     VFFALLLLHIVSFVSDMVSTIKHLNSFGSILSSIVFISLLLTFFAMNSHKVQMEKEIA
                     LKQKKFEQKHLQ"
     gene            complement(711..836)
                     /gene="comC"
                     /locus_tag="VU534_001587"
     CDS             complement(711..836)
                     /gene="comC"
                     /locus_tag="VU534_001587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000799689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence-stimulating peptide ComC"
                     /protein_id="HEU1514148.1"
                     /translation="MKNTVKLEQFVALKEKDLQKIKGGEMRISRIILDFLFLRKK"
     gene            complement(1001..1074)
                     /locus_tag="VU534_001588"
     tRNA            complement(1001..1074)
                     /locus_tag="VU534_001588"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1038..1040),aa:Arg,seq:tct)
     gene            complement(1118..1597)
                     /gene="rlmH"
                     /locus_tag="VU534_001589"
     CDS             complement(1118..1597)
                     /gene="rlmH"
                     /locus_tag="VU534_001589"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000695929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HEU1514149.1"
                     /translation="MKIKVVTVGKLKEKYLKDGIAEYSKRISRFAKFEMIELSDEKTP
                     DKASESENQKILEIEGQRILSKIADRDFVIVLAIEGKTFFSEEFSKQLEETSIKGFST
                     LTFIIGGSLGLSSSVKNRANLSVSFGRLTLPHQLMRLVLVEQIYRAFTIQQGFPYHK"
     gene            1780..2961
                     /locus_tag="VU534_001590"
     CDS             1780..2961
                     /locus_tag="VU534_001590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trypsin-like peptidase domain-containing
                     protein"
                     /protein_id="HEU1514150.1"
                     /translation="MKHLKTFYKKWFQLLVVIVISFFSGALGSFSITQLTQKSSVNNS
                     NNNSTITQTAYKNENSTTQAVNKVKDAVVSVITYSANRQNSVFGNDDTDTDSQRISSE
                     GSGVIYKKNDKEAYIVTNNHVINGASKVDIRLSDGTKVPGEIVGADTFSDIAVVKISS
                     EKVTTVAEFGDSSKLTVGETAIAIGSPLGSEYANTVTQGIVSSLNRNVSLKSEDGQAI
                     STKAIQTDTAINPGNSGGPLINIQGQVIGITSSKIATNGGTSVEGLGFAIPANDAINI
                     IEQLEKNGKVTRPALGIQMVNLSNVSTSDIRRLNIPSNVTSGVIVRSVQSNMPANGHL
                     EKYDVITKVDDKEIASSTDLQSALYNHSIGDTIKITYYRNGKEETTSIKLNKSSGDLE
                     S"
     gene            3019..3777
                     /locus_tag="VU534_001591"
     CDS             3019..3777
                     /locus_tag="VU534_001591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000410347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HEU1514151.1"
                     /translation="MEKFEMISITDIQKNPYQPRKEFDREKLDELAQSIKENGVIQPI
                     IVRQSPVIGYEILAGERRYRASLLAGLRSIPAVVKQISDQEMMVQSIIENLQRENLNP
                     IEEARAYESLVEKGFTHAEIADKMGKSRPYISNSIRLLSLPEQILSEVENGKLSQAHA
                     RSLVGLNKEQQDYFFQRIIEEDISVRKLEALLTEKKQKKQQKTNHFIQNEEKQLRKLL
                     GLDVEIKLSKKDSGKIIISFSNQEEYSRIINSLK"
     gene            3990..5351
                     /gene="dnaA"
                     /locus_tag="VU534_001592"
     CDS             3990..5351
                     /gene="dnaA"
                     /locus_tag="VU534_001592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HEU1514152.1"
                     /translation="MKEKQFWNRILEFAQERLTRSMYDFYAIQAELIKVEENVATIFL
                     PRSEMEMVWEKQLKDIIVVAGFEIYDAEITPHYIFTKPQDTTSSQVEEATNLTLYNYS
                     PKLVSIPYSDTGLKEKYTFDNFIQGDGNVWAVSAALAVSEDLALTYNPLFIYGGPGLG
                     KTHLLNAIGNEILKNIPNARVKYIPAESFINDFLDHLRLGEMEKFKKTYRSLDLLLID
                     DIQSLSGKKVATQEEFFNTFNALHDKQKQIVLTSDRSPKHLEGLEERLVTRFSWGLTQ
                     TITPPDFETRIAILQSKTEHLGYNFQSDTLEYLAGQFDSNVRDLEGAINDITLIARVK
                     KIKDITIDIAAEAIRARKQDVSQMLVIPIDKIQTEVGNFYGVSIKEMKGSRRLQNIVL
                     ARQVAMYLSRELTDNSLPKIGKEFGGKDHTTVIHAHAKIKSLIDQDDNLRLEIESIKK
                     KIK"
     gene            5510..6646
                     /gene="dnaN"
                     /locus_tag="VU534_001593"
     CDS             5510..6646
                     /gene="dnaN"
                     /locus_tag="VU534_001593"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HEU1514153.1"
                     /translation="MIHFSINKNLFLQALNTTKRAISSKNAIPILSTVKIDVTNEGIT
                     LIGSNGQISIENFISQKNEDAGLLITSLGSILLEASFFINVVSSLPDVTLDFKEIEQN
                     QIVLTSGKSEITLKGKDSEQYPRIQEISASTPLILETKLLKKIINETAFAASTQESRP
                     ILTGVHFVLSQHKELKTVATDSHRLSQKKLTLEKNSDDFDVVIPSRSLREFSAVFTDD
                     IETVEIFFANNQILFRSENISFYTRLLEGNYPDTDRLIPTDFNTTITFNVVNLRQSME
                     RARLLSSATQNGTVKLEIKDGVVSAHVHSPEVGKVNEEIDTDQVTGEDLTISFNPTYL
                     IDSLKALNSEKVTISFISAVRPFTLVPADTDEDFMQLITPVRTN"
     gene            6711..6905
                     /locus_tag="VU534_001594"
     CDS             6711..6905
                     /locus_tag="VU534_001594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 family protein"
                     /protein_id="HEU1514154.1"
                     /translation="MYQVGNFVEMKKSHACTIKSTGKKANRWEITRVGADIKIKCSNC
                     EHVVMMGRYDFERKMNKIID"
     gene            6989..8104
                     /gene="ychF"
                     /locus_tag="VU534_001595"
     CDS             6989..8104
                     /gene="ychF"
                     /locus_tag="VU534_001595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002269933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HEU1514155.1"
                     /translation="MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMV
                     EVPDERLQKLTEMITPKKTVPTTFEFTDIAGIVKGASKGEGLGNKFLANIREVDAIVH
                     VVRAFDDENVMREQGREDAFVDPLADIDTINLELILADLESVNKRYARVEKMARTQKD
                     KESVAEFNVLQKIKPVLEDGKSARTIEFTDKEQKVVKGLFLLTTKPVLYVANVDEDVV
                     SEPDSIDYVKQIREFAATENAEVVVISARAEEEISELNDEDKKEFLEAIGLTESGVDK
                     LTRAAYHLLGLGTYFTAGEKEVRAWTFKRGMKAPQAAGIIHSDFEKGFIRAVTMSYED
                     LVKYGSEKAVKEAGRLREEGKEYIVQDGDIMEFRFNV"
     gene            8175..8744
                     /locus_tag="VU534_001596"
     CDS             8175..8744
                     /locus_tag="VU534_001596"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HEU1514156.1"
                     /translation="MTKLLVGLGNPGDKYFETKHNVGFMLIDQLAKKQNVTFTHDKIF
                     QADLASFFLNGEKIYLVKPTTFMNESGKAVHALLTYYGLDIDDLLIIYDDLDMEVGKI
                     RLRAKGSAGGHNGIKSIIQHIGTQVFNRVKIGIGRPKNGMSVVHHVLSKFDRDDYIGI
                     LQSVDKVDDSVNYYLQEKNFEKTMQRYNG"
     gene            8745..12254
                     /gene="mfd"
                     /locus_tag="VU534_001597"
     CDS             8745..12254
                     /gene="mfd"
                     /locus_tag="VU534_001597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000258090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HEU1514157.1"
                     /translation="MVTLLDLFSENDQIKKWHQNLTDKKRQLILGLSTSTKALAIASS
                     LEKEDRIVLLTSTYGEAEGLVSDLISILGEELVYPFLVDDAPMVEFLMSSQEKIISRV
                     EALRFLTDSSKKGILVCNIAASRLILPSPNAFKDSIVKISVGEEYDQHAFIHQLKENG
                     YRKVTQVQTQGEFSLRGDILDIFEISQLEPCRIEFFGDEIDGIRSFEVETQLSKENKT
                     ELTIFPASDMLLREKDYQRGQSALEKQISKTLSPILKSYLEEILSSFHQKQSHADSRK
                     FLSLCYDKTWTVFDYIEKDTPIFFDDYQKLMNQYEVFERDLAQYFTEELQNSKAFSDM
                     QYFSDIEQIYKKQSPVTFFSNLQKGLGNLKFDKIYQFNQYPMQEFFNQFSFLKEEIER
                     YKKMDYTIILQSSNSMGSKTLEDMLEEYQIKLDSRDKTNICKESVNLIEGNLRHGFHF
                     VDEKILLITEHEIFQKKLKRRFRRQHVSNAERLKDYNELEKGDYVVHHIHGIGQYLGI
                     ETIEIKGIHRDYVSVQYQNGDQISIPVEQIHLLSKYISSDGKAPKLNKLNDGHFKKAK
                     QKVKNQVEDIADDLIKLYSERSQLKGFAFSADDDDQDAFDDAFPYVETDDQLRSIEEI
                     KRDMQASQPMDRLLVGDVGFGKTEVAMRAAFKAVNDHKQVVILVPTTVLAQQHYTNFK
                     ERFQNFAVNIDVLSRFRSKKEQTATLEKLKNGQVDILIGTHRVLSKDVVFADLGLMII
                     DEEQRFGVKHKETLKELKKQVDVLTLTATPIPRTLHMSMLGIRDLSVIETPPTNRYPV
                     QTYVLEKNDSVIRDAVLREMERGGQVYYLYNKVDTIVQKVSELQELIPEASIGYVHGR
                     MSEVQLENTLLDFIEGQYDILVTTTIIETGVDIPNANTLFIENADHMGLSTLYQLRGR
                     VGRSNRIAYAYLMYRPEKSISEVSEKRLEAIKGFTELGSGFKIAMRDLSIRGAGNLLG
                     KSQSGFIDSVGFELYSQLLEEAIAKRNGNANANTRTKGNAELILQIDAYLPDTYISDQ
                     RHKIEIYKKIRQIDNRVNYEELQEELIDRFGEYPDVVAYLLEIGLVKSYLDKVFVQRV
                     ERKDNKITIQFEKVTQRLFLAQDYFKALSVTNLKAGIAENKGLMELVFDVQNKKDYEI
                     LEGLLIFGESLLEIKESKEENSI"
     gene            12312..12578
                     /locus_tag="VU534_001598"
     CDS             12312..12578
                     /locus_tag="VU534_001598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001234972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HEU1514158.1"
                     /translation="MRLDKYLKVSRIIKRRTVAKEVADKGRIKVNGILAKSSTDLKVN
                     DQVEIRFGNKLLLVKVLEMKDSTKKEDAAGMYEIISETRVEENV"
     gene            12571..12939
                     /locus_tag="VU534_001599"
     CDS             12571..12939
                     /locus_tag="VU534_001599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HEU1514159.1"
                     /translation="MSKNIVQLNNSFIQNEYQRRRYLMKERQKRNRFMGGVLILIMLL
                     FILPTFNLAQSYQQLLQRRQQLADLQTQYQTLSDEKDKETAFATKLKDEDYAAKYTRA
                     KYYYSKSREKVYTIPDLLQR"
     gene            13059..14327
                     /locus_tag="VU534_001600"
     CDS             13059..14327
                     /locus_tag="VU534_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A beta-lactamase-related serine hydrolase"
                     /protein_id="HEU1514160.1"
                     /translation="MRKFLIILLLPSFLTISKVVSTEKEVVYTSKEIYYLSQSDFGIY
                     FREKLSSPMVYGEVPVYANEDLVVESGKLTPKTSFQITEWRLNKQGIPVFKLSNHQFI
                     AADKRFLYDQSEVTPTIKKVWLESDFKLYNSPYDLKEVKSSLSAYSQVSIDKTMFVEG
                     REFLHIDQAGWVAKESTSEEDNRMSKVQEMLSEKYQKDSFSIYVKQLTTGKEAGINQD
                     EKMYAASVLKLSYLYYTQEKINEGLYQLDTTVKYVSAVNDFPGSYKPEGSGSLPKKED
                     NKEYSLKDLITKVSKESDNVAHNLLGYYISNQSDATFKSKMSAIMGDDWDPKEKLISS
                     KMAGKFMEAIYNQNGFVLESLTKTDFDSQRIAKGVSVKVAHKIGDADEFKHDTGVVYA
                     DSPFILSIFTKNSDYDTISKIAKDVYEVLK"
     gene            14324..15601
                     /gene="tilS"
                     /locus_tag="VU534_001601"
     CDS             14324..15601
                     /gene="tilS"
                     /locus_tag="VU534_001601"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HEU1514161.1"
                     /translation="MREPDFLNHFLKKGYFKKHAKAVLALSGGLDSMFLFKVLSTYQK
                     ELEIELILAHVNHKQRIESDWEEKELRKLAAEAELPIYISNFSGEFSEARARNFRYDF
                     FQEVMKKTGATALVTAHHADDQVETIFMRLIRGTRLRYLSGIKEKQVVGEIEIIRPFL
                     HFQKKDFPSIFHFEDTSNQENHYFRNRIRNSYLPELEKENPRFRDAILGIGNEILDYD
                     LAIAELSNNINVEDLQQLFSYSESTQRVLLQTYLNRFPDLNLTKAQFAEVQQILKSKS
                     QYRHPIKNGYELIKEYQQFQICKISPQADEKEDELVLHYQNQVAYQGYLFSFGLPLEG
                     ELIQQIPVSRETSIHIRHRKTGDVLIKNGHRKKLRRLFIDLKIPMEKRNSALIIEQFG
                     EIVSILGIATNNLSKKTKNDIMNTVLYIEKIDR"
     gene            15605..16147
                     /gene="hpt"
                     /locus_tag="VU534_001602"
     CDS             15605..16147
                     /gene="hpt"
                     /locus_tag="VU534_001602"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HEU1514162.1"
                     /translation="MLENDIKKVLVSHDEITEAAKKLGAQLTKDYAGKNPILVGILKG
                     SIPFMAELVKHIDTHIEMDFMMVSSYHGGTASSGVINIKQDVTQDIKGRHVLFVEDII
                     DTGQTLKNLRDMFKEREAASVKIATLLDKPEGRVVEIEADYTCFTIPNEFVVGYGLDY
                     KENYRNLPYIGVLKEEVYSN"
     gene            16163..18121
                     /gene="ftsH"
                     /locus_tag="VU534_001603"
     CDS             16163..18121
                     /gene="ftsH"
                     /locus_tag="VU534_001603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000744538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HEU1514163.1"
                     /translation="MKKQNNGLIKNPFLWLLFIFFLVTGFQYFYSGNNSGGSQQINYT
                     ELVQEITDGNVKELTYQPNGSVIEVSGVYKNPKTSKEETGIQFFTPSVTKVEKFTSTI
                     LPADTTVSELQKLATDHKAEVTVKHESSSGIWINLLVSIVPFGILFFFLFSMMGNMGG
                     GNGRNPMSFGRSKAKAANKEDIKVRFSDVAGAEEEKQELVEVVEFLKDPKRFTKLGAR
                     IPAGVLLEGPPGTGKTLLAKAVAGEAGVPFFSISGSDFVEMFVGVGASRVRSLFEDAK
                     KAAPAIIFIDEIDAVGRQRGVGLGGGNDEREQTLNQLLIEMDGFEGNEGIIVIAATNR
                     SDVLDPALLRPGRFDRKVLVGRPDVKGREAILKVHAKNKPLAEDVDLKLVAQQTPGFV
                     GADLENVLNEAALVAARRNKSIIDASDIDEAEDRVIAGPSKKDKTVSQKERELVAYHE
                     AGHTIVGLVLSNARVVHKVTIVPRGRAGGYMIALPKEDQMLLSKEDMKEQLAGLMGGR
                     VAEEIIFNVQTTGASNDFEQATQMARAMVTEYGMSEKLGPVQYEGNHAMLGAQSPQKS
                     ISEQTAYEIDEEVRSLLNEARNKAAEIIQSNRETHKLIAEALLKYETLDSTQIKALYE
                     TGKMPEAVEEESHALSYDEVKSKMNDEK"
BASE COUNT         6315 a         2862 c         3467 g         5496 t
ORIGIN      
        1 ctgtaaatgt ttctgttcaa atttcttctg cttcaaagca atctctttct ccatttgaac
       61 tttatgagaa ttcattgcaa agaaggtcaa aaggagagag ataaagacaa tagatgacaa
      121 aatacttcca aaactattca aatgtttaat cgtacttacc atatctgaaa cgaaagatac
      181 aatatgtagc aatagtaaag caaaaaatac ttttttcaag aaaggataaa ggtagtcctt
      241 gtcaaaatag gctagttcca aatggaaata gtaaatgatt tttaatgtaa caaaataggt
      301 taacaccgtc acaacgaaaa agaatgggaa atgatattgt aaaacaaaat tatctcctgt
      361 tatagaggag aaaattacgg acagaaagtt atgagtgctc tcatataaaa gagatagtag
      421 taaacttagg aatagtcctc tatccctctc atactgtttc atccatcgaa aataggaata
      481 taagcccaaa ggaaataaaa atctttcaat ccctatttta tctaaatata gaagataaaa
      541 ggaaaattca agtactattt cagttagtaa tgtataagca ccaaaaacgt ataattcttt
      601 tctatttatt cgacctttac aaattaaacg gtaactgtga ctaataatta aaaaatgaac
      661 aataactgtc ccaaatccaa gtaaatccat tactctttct ccttatttca ttactttttt
      721 cgtaggaaaa gaaaatcaag gatgattctt gaaatcctca tctccccacc tttaatcttt
      781 tgtaagtctt tttccttcaa agctacaaac tgttccaatt taactgtgtt tttcataata
      841 aaatctccta aaatgttttt tcttgtaagc taacttacaa aaaccattat acaaaatgga
      901 atttcgtttt agataaaatt ctctcaactg tcattttttt ctcccaaagt gtactttttt
      961 aagaaaaaag ccgggaaaat tcccagcttt gctattatat tgatcccagc aggattcgaa
     1021 cctgcgaccg ttcgcttaga aggcgaatgc tctatccagc tgagctatga gacctaatac
     1081 aattattcta ccaaaaattc aattaaaagt caattttcta tttatggtag gggaatccct
     1141 gctgaatcgt aaaagcgcga tagatttgtt caacaagaac tagtctcatt aactgatggg
     1201 gtaaggttag gcgaccaaaa ctgacagaaa gattggctct attttttaca gatgatgata
     1261 atcctaaact tcccccaata ataaaagtaa gagtagaaaa tccttttata gaagtttctt
     1321 ctaactgctt actaaattct tctgagaaga aagttttccc ttcaatggct aacacaataa
     1381 cgaaatcacg gtcagcaatt tttgataaaa ttctctgacc ttctatttct aaaatctttt
     1441 gattttctga ttcactggcc ttatctggtg ttttttcatc tgataactca atcatttcaa
     1501 acttagcaaa tctagaaatt cgttttgaat actctgcgat accatctttt aaatactttt
     1561 ctttcagttt cccaactgtt acaactttaa ttttcatgac tctattctaa catattctct
     1621 attttttcac atcttattca caaaataaaa aatagatttc aattaagaaa atcacaattt
     1681 caaaagagtt atccacagtt tgtgtaaaac ttttgtgttt aagttataat taagctagtc
     1741 agtttatact ttcagtaatt caaacatatg gaggcaaata tgaaacatct aaaaacattt
     1801 tacaaaaaat ggtttcaatt attagtcgtt atcgtcatta gcttttttag tggagccttg
     1861 ggtagttttt caataactca actaactcaa aaaagtagtg taaacaactc taacaacaat
     1921 agtactatta cacaaactgc ctataagaac gaaaattcaa caacacaggc tgttaacaaa
     1981 gtaaaagatg ctgttgtttc tgttattact tattcggcaa acagacaaaa tagcgtattt
     2041 ggcaatgatg atactgacac agattctcag cgaatctcta gtgaaggatc tggagttatt
     2101 tataaaaaga atgataaaga agcttacatc gtcaccaaca atcacgttat taatggcgcc
     2161 agcaaagtag atattcgatt gtcagatggg actaaagtac ctggagaaat tgtcggagct
     2221 gacactttct ctgatattgc tgtcgtcaaa atctcttcag aaaaagtgac aacagtagct
     2281 gagtttggtg attctagtaa gttaactgta ggagaaactg ctattgccat cggtagcccg
     2341 ttaggttctg aatatgcaaa tactgtcact caaggtatcg tatccagtct caatagaaat
     2401 gtatccttaa aatcggaaga tggacaagct atttctacaa aagccatcca aactgatact
     2461 gctattaacc caggtaactc tggcggccca ctgatcaata ttcaagggca ggttatcgga
     2521 attacctcaa gtaaaattgc tacaaatgga ggaacatctg tagaaggtct tggtttcgca
     2581 attcctgcaa atgatgctat caatattatt gaacagttag aaaaaaacgg aaaagtgacg
     2641 cgtccagctt tgggaatcca gatggttaat ttatctaatg tgagtacaag cgacatcaga
     2701 agactcaata ttccaagtaa tgttacatct ggtgtaattg ttcgttcggt acaaagtaat
     2761 atgcctgcca atggtcacct tgaaaaatac gatgtaatta caaaagtaga tgacaaagag
     2821 attgcttcat caacagactt acaaagtgct ctttacaacc attctatcgg agacaccatt
     2881 aagataacct actatcgtaa cgggaaagaa gaaactacct ctatcaaact taacaagagt
     2941 tcaggtgatt tagaatctta attgacatct atgtaaagaa agctttacat aagagaaaag
     3001 atgtgttagt gtagaatcat ggaaaaattt gaaatgattt ctatcacaga tatacaaaaa
     3061 aatccctatc aaccccgaaa agaatttgat agagaaaaac tagatgaact agcacagtct
     3121 atcaaagaaa atggggtcat tcaaccgatt attgttcgtc aatctcctgt tattggttat
     3181 gaaatccttg caggagagag acgctatcgg gcttcacttt tagctggtct acggtctatc
     3241 ccagctgttg ttaaacagat ttcagaccaa gagatgatgg tccagtccat tattgaaaat
     3301 ttacagagag aaaatttaaa cccaatagaa gaagcacgcg cctatgaatc tctcgtagag
     3361 aaaggattca cccatgctga aattgcagat aagatgggca agtctcgtcc atatatcagc
     3421 aactccattc gtttactttc cttgccagaa cagattcttt cagaagtaga aaatggcaaa
     3481 ctatcacaag cccatgcgcg ttccctagtt gggttaaata aggaacaaca agactatttc
     3541 tttcaacgga ttatagaaga agatatttct gtaaggaaat tagaagctct tctgacagag
     3601 aaaaaacaaa agaaacagca aaaaactaat catttcatac aaaatgaaga aaaacagtta
     3661 agaaaactac tcggattaga tgtagaaatt aaactatcta aaaaagacag tggaaaaatc
     3721 attatttctt tttcaaatca agaagaatat agtagaatta tcaacagcct gaaataaggc
     3781 tgttctttta tttttttatc tcacaaggtt atccactatg tttttcgata aaaagcttaa
     3841 taaatcaata atttcttctt ttatccccaa cctgtggata aagtttggta acattgtgga
     3901 ttatttttca cagcttgtgg aaaattcttg ctatctatgg taaaatatct ctagtattaa
     3961 acttttaaat agtaaaggag gagaaaggat tgaaagaaaa acaattttgg aatcgtatat
     4021 tagaatttgc acaagaaaga ctgactcgat ccatgtatga tttctatgct attcaagctg
     4081 aactcatcaa ggtagaggaa aatgttgcca ctatatttct acctcgctct gaaatggaaa
     4141 tggtctggga aaaacaacta aaagatatta ttgtagtagc tggttttgaa atttatgacg
     4201 ctgaaataac tccccactat attttcacca aacctcaaga tacgactagc tcacaagttg
     4261 aagaagctac aaatttaact ctttataact atagtccaaa gttagtatct attccttatt
     4321 cagatacggg attaaaagaa aagtatacct ttgataactt tattcaaggg gatggaaatg
     4381 tttgggctgt atcagccgct ttagctgtct ctgaagattt ggctctgacc tataaccctc
     4441 tttttatcta tggaggacca ggccttggta agactcactt attaaacgct attggaaatg
     4501 aaattctaaa aaatattcct aatgcgcgtg ttaaatatat ccctgccgaa agctttatta
     4561 atgactttct tgatcaccta agacttgggg aaatggaaaa gtttaaaaag acctatcgta
     4621 gtcttgatct tttgttaatc gatgatatcc agtcactcag cggaaaaaaa gtcgcaactc
     4681 aggaagaatt tttcaatacc tttaacgccc ttcatgacaa gcaaaaacag attgtcctaa
     4741 cgagtgatcg tagtccaaaa catctagaag ggctcgagga gaggcttgtc acgcgtttta
     4801 gttggggatt gacacaaact atcacccccc ctgactttga aacacgtatt gccattttac
     4861 aaagtaagac ggaacattta ggctacaatt tccaaagtga tactctagaa tacctagctg
     4921 ggcaatttga ttcaaatgtt cgagatcttg agggagccat caacgacatc actttaattg
     4981 ccagagtaaa aaaaatcaag gatatcacta ttgatattgc tgcagaagcc attagagccc
     5041 gcaaacaaga tgttagccaa atgctcgtca tcccaattga taaaatccaa actgaagttg
     5101 gtaactttta tggtgttagt atcaaagaaa tgaagggaag tagacgcctt caaaatattg
     5161 ttttggcccg tcaagtagcc atgtatttat ctagagaact aacagataat agtcttccaa
     5221 aaattgggaa ggaatttggg ggaaaagatc ataccacagt cattcatgcc catgccaaaa
     5281 taaaatcttt gattgatcaa gacgataatt tacgtttaga aattgaatca atcaaaaaga
     5341 aaatcaaata atttgtggat aacttttagt tttttatctt ttttatccac attttttaaa
     5401 caagctaaaa aacttgatat gacttgttta aaggctgttt tccacagatt tcacagactc
     5461 tattattact attatctttc taatactaaa aataaataaa ggagaatcca tgattcattt
     5521 ttcaattaat aaaaatttat ttctacaagc attaaatact actaagagag ctattagttc
     5581 taaaaatgcc attcctattt tatcaacagt aaaaattgac gtgaccaatg aaggtattac
     5641 tttaattggt tcaaatggtc aaatttcaat tgaaaatttt atttctcaaa aaaatgaaga
     5701 tgctggtttg ttaattactt ctttaggttc gatccttctt gaagcttctt tctttatcaa
     5761 tgtagtatct agtttacctg atgtaactct tgattttaaa gaaattgaac aaaatcaaat
     5821 tgttttaacc agtggcaaat cagaaattac cctaaaagga aaagatagcg aacaatatcc
     5881 acgaatccaa gaaatttcag caagcactcc tttaatactt gaaacaaaat tactcaagaa
     5941 aattattaat gaaacagcct ttgctgcaag tacacaagag agtcgtccga ttttaacagg
     6001 tgtccacttc gtattgagtc aacacaaaga gttaaaaaca gttgcaacag actctcatcg
     6061 cctaagccag aaaaaattga ctcttgaaaa aaatagtgat gattttgatg tcgtaattcc
     6121 tagccgttct ctacgcgaat tttcagcggt atttacagat gatatcgaaa ctgtagagat
     6181 tttctttgcc aataaccaaa tcctctttag aagcgaaaat attagcttct atactcgtct
     6241 cctagaagga aactatcctg atacagatcg cttgattcca acagacttta acactactat
     6301 tacttttaat gtggtaaact tacgccagtc aatggagcgt gcccgtcttt tatcaagtgc
     6361 gactcaaaat ggtactgtga aacttgaaat taaggatggg gttgttagcg cccatgttca
     6421 ctctccagaa gttggtaaag taaacgaaga aatcgatact gatcaggtta ctggtgaaga
     6481 tttgaccatt agtttcaacc caacttactt gattgattct cttaaagctt taaatagcga
     6541 aaaggtgact attagcttta tctcagctgt tcgtccattt actcttgtgc cagcagatac
     6601 tgacgaagac ttcatgcagc tcattacacc agttcgtaca aattaagtga aagaggttga
     6661 gcctggctcg cctcttttat gatataatcg aaaaagaaaa ggagagtagt atgtatcaag
     6721 ttggaaattt tgttgagatg aaaaaatcac acgcttgtac aatcaagtcg actggtaaaa
     6781 aggctaatcg ttgggaaatt acacgtgtag gagcagatat caaaataaaa tgtagtaatt
     6841 gtgagcatgt tgtcatgatg gggcgatatg attttgagcg aaaaatgaat aaaattattg
     6901 actgagaacc cttagttaga gggttagcac tttatccctt tttgtgttat aatattaggg
     6961 attgaaatga aaacggagaa tgagaaatat ggctttgaca gcaggtatcg ttggtttgcc
     7021 aaacgttggt aaatcaacac tatttaatgc aattacaaaa gcaggagcag aggcagcaaa
     7081 ctacccattt gcgacgattg atccaaatgt tggaatggtg gaagttccag atgaacgcct
     7141 acaaaaacta actgaaatga taactcctaa aaagacagtt cccacaacat ttgaatttac
     7201 agatattgca gggattgtaa aaggagcttc aaaaggagag gggctaggga ataaattctt
     7261 ggccaatatt cgtgaagtag atgcgattgt tcacgtagtt cgtgcttttg atgatgaaaa
     7321 tgtaatgcgc gagcaaggac gtgaagacgc ctttgtagat ccacttgcag atattgatac
     7381 cattaatctg gaattgattc ttgctgactt agaatcagtg aacaaacgat atgcgcgtgt
     7441 agaaaagatg gcacgtacgc aaaaagataa agaatcagta gcagaattca atgttcttca
     7501 aaagattaaa ccagtcctag aagacgggaa atcagctcgt accattgaat ttacagataa
     7561 ggaacaaaag gttgtcaaag gtcttttcct tttgacgact aaaccagttc tttatgtagc
     7621 taatgtggac gaggatgtgg tttcagaacc tgactctatc gactatgtca aacaaattcg
     7681 tgaatttgca gcgacagaaa atgctgaagt agtcgttatt tctgcgcgtg ctgaggaaga
     7741 aatttctgaa ttgaatgatg aagataaaaa agagtttctt gaagccattg gtttgacaga
     7801 atcaggtgta gataagttga cgcgtgcagc ttaccacttg cttggattgg gaacttactt
     7861 cacagctggt gaaaaagaag ttcgcgcttg gactttcaaa cgtggtatga aggctcctca
     7921 agcagctggt attatccact cagactttga aaaaggcttt attcgtgcag taaccatgtc
     7981 atatgaagat ctagtgaaat acggatctga aaaggccgta aaagaagctg gacgcttgcg
     8041 tgaagaagga aaagaatata tcgttcaaga tggcgatatc atggaattcc gctttaatgt
     8101 ctaaaaatta ataaatggtg tcaattaggt tggaaaaaaa ttccaaccct tttggctttt
     8161 gaaaggaaaa ataaatgacc aaattacttg taggcttggg aaatccaggg gataaatatt
     8221 ttgaaacaaa acacaatgtt ggttttatgt tgattgatca actagcgaag aaacagaatg
     8281 tcacttttac acacgataag atatttcaag ctgacctagc atcctttttc ctaaatggag
     8341 aaaaaattta tctggttaaa ccaacgacct ttatgaatga aagtggaaaa gcagttcatg
     8401 ctttattaac ttactatggt ttggatattg acgatttact tatcatttac gatgatcttg
     8461 acatggaagt tgggaaaatt cgtttaagag caaaaggctc agcaggtggt cataatggta
     8521 tcaagtctat tattcaacat ataggaactc aggtctttaa ccgtgttaag attggaattg
     8581 gaagacctaa aaatggtatg tcagttgttc atcatgtttt gagtaagttt gacagggatg
     8641 attatatcgg tattttacag tctgttgaca aagttgacga ttctgtaaac tactatttac
     8701 aagagaaaaa ttttgagaaa acaatgcaga ggtataacgg ataaatggtg accttattag
     8761 atttattctc agaaaatgat cagattaaaa aatggcatca aaatttaaca gataagaaaa
     8821 gacaactaat acttggttta tcaacatcta ctaaggctct tgcaattgca agcagtttag
     8881 aaaaagaaga taggattgtg ttattgacgt caacttatgg agaagcagaa ggacttgtta
     8941 gtgatcttat ttctatcttg ggtgaggaac tcgtctatcc atttttggta gatgatgctc
     9001 ctatggtgga gtttttgatg tcttcacagg aaaaaattat ttcacgggtt gaagccttgc
     9061 gttttttgac tgattcatct aagaaaggga ttttagtttg taatatcgca gcaagtcgat
     9121 tgattttacc gtctcccaat gcattcaaag atagtattgt aaaaatctca gttggtgaag
     9181 aatatgatca acacgcgttt atccatcagt taaaggaaaa tggctatcga aaagttactc
     9241 aagtacaaac tcagggcgaa tttagtcttc gaggagatat tttagatatt tttgaaatat
     9301 cccagttaga accttgtcga attgagtttt ttggtgatga aattgatggt atcaggtcat
     9361 ttgaagtaga aacacaatta tcgaaagaaa ataagacaga actcactatc tttccagcta
     9421 gtgatatgct tttgagagaa aaggattatc aacgaggaca gtcagcttta gaaaaacaaa
     9481 tttcaaaaac tttatcacct attttgaaat catacctaga agaaattctt tcaagttttc
     9541 accaaaaaca aagtcatgca gactctcgga agtttttatc tttgtgctat gataagacat
     9601 ggactgtctt tgattatatt gaaaaagata ctccaatatt ctttgatgat tatcaaaaat
     9661 tgatgaatca gtatgaagtc tttgaaagag acttagcgca gtactttaca gaagaattac
     9721 agaatagtaa agcattttct gatatgcagt atttttctga tattgaacaa atctataaaa
     9781 aacaaagtcc agtgaccttt ttctctaatc ttcaaaaggg tttaggaaat ctcaaatttg
     9841 acaaaattta tcaattcaat caatatccta tgcaggaatt tttcaatcag ttttcttttc
     9901 taaaagaaga aattgaacga tataaaaaaa tggattacac cattattctg cagtctagca
     9961 attcaatggg aagtaaaaca ttggaggata tgttagagga atatcagatt aaattggatt
    10021 ctagagataa gacaaatatc tgtaaagaat ctgtaaactt aatagagggt aatctcagac
    10081 atggttttca ttttgtagat gaaaagattt tattgataac tgaacatgag atttttcaaa
    10141 agaaattaaa gcgtcgtttt cgaagacaac atgtttcaaa tgcagagaga ttaaaagatt
    10201 acaatgaact tgaaaaaggg gactatgttg tccatcatat ccatgggatt ggtcaatatc
    10261 taggaattga aaccattgaa atcaagggaa ttcatcgcga ttatgtcagt gtccaatacc
    10321 aaaatggtga tcaaatttct atccccgtgg aacagattca tctactgtcc aaatatattt
    10381 caagtgatgg taaagctcca aaactcaata aattaaatga cggtcatttt aaaaaggcca
    10441 agcaaaaggt taagaaccag gtagaggata tagctgatga tttaatcaaa ctctactctg
    10501 aacgtagtca gttgaagggt tttgctttct cagctgatga tgatgatcaa gatgcctttg
    10561 atgatgcttt cccttatgtt gaaacggatg atcaacttcg tagtattgag gaaatcaaga
    10621 gggatatgca ggcttctcag ccaatggatc gacttttagt tggggatgtt ggttttggaa
    10681 agactgaagt tgctatgcgt gcagccttta aagcagtcaa tgatcacaaa caggttgtca
    10741 ttctagttcc gacgacggtt ttagcgcaac agcactatac gaattttaag gaacgattcc
    10801 aaaattttgc agttaatatt gatgtgttga gtcgctttag aagtaaaaaa gagcagactg
    10861 caacacttga aaaattgaaa aacggtcaag tcgatatttt gattggaaca catcgtgttt
    10921 tgtcaaaaga tgttgtgttt gctgatttgg gcttgatgat tattgatgag gaacagcgat
    10981 ttggtgtcaa gcataaggaa actttgaaag aactgaagaa acaagtggat gtcctaacct
    11041 tgaccgctac gccaatccct cgtaccctcc atatgtctat gctgggaatc agagatttat
    11101 ctgttattga aactccgccg actaatcgct atcctgttca gacctatgtt ttggaaaaga
    11161 atgatagtgt cattcgtgat gctgtcttgc gtgaaatgga gcgtggaggt caagtttatt
    11221 atctttacaa caaagttgac acaattgttc agaaggtttc agaattacag gagttgattc
    11281 cggaggcttc gattggatat gttcatggtc gaatgagtga agtccagttg gaaaatactc
    11341 tattagactt tattgaggga caatacgata tcttggtgac gactactatt attgagacag
    11401 gggtggacat tccaaatgct aatactttat ttattgaaaa tgcggaccat atgggcttgt
    11461 caaccttata tcagttaaga ggaagagtcg gtcgtagtaa tcgtattgct tatgcttatc
    11521 tcatgtatcg tccagaaaaa tcaatcagtg aagtctctga aaagagatta gaagcgatta
    11581 aaggatttac agaattgggc tctggcttta agattgcaat gcgagatctt tcgattcgtg
    11641 gagcaggaaa tcttttagga aaatcccagt ctggtttcat tgattctgtt ggttttgaat
    11701 tgtattcgca gttattagag gaagctattg ctaaacgaaa cggtaatgct aacgctaaca
    11761 caagaaccaa agggaatgct gagttgattt tgcaaattga tgcctatctt cctgatactt
    11821 atatttctga tcaacgacat aagattgaaa tttacaagaa aattcgtcaa attgacaacc
    11881 gtgtcaatta tgaagagtta caagaggagt tgatagaccg ttttggagaa tacccagatg
    11941 tagtagccta tctgttagag attggtttgg tcaaatcata cttggacaag gtctttgttc
    12001 aacgtgtgga aagaaaagat aataaaatta caattcaatt tgaaaaagtc actcaacgac
    12061 tgtttttagc tcaagattat tttaaagctt tatccgtaac gaacttaaaa gcaggcatcg
    12121 ctgagaataa gggattaatg gagcttgtat ttgatgtcca aaataagaaa gattatgaaa
    12181 ttttagaagg tttgctgatt tttggagaaa gtttattaga gataaaagag tctaaggaag
    12241 aaaattccat ttgatatttt tcttctataa aatagataaa aatggtacaa taataaattg
    12301 aggtaataag gatgagatta gataaatatt taaaagtatc gcgaattatc aagcgtcgta
    12361 cagtcgcaaa ggaagtagca gataaaggta gaatcaaggt taatggaatc ttggccaaaa
    12421 gttcaacgga cttgaaagtt aatgaccaag ttgaaattcg ctttggcaat aagttgctgc
    12481 ttgtaaaagt actagagatg aaagatagta caaaaaaaga agatgcagca ggaatgtatg
    12541 aaattatcag tgaaacacgg gtagaagaaa atgtctaaaa atattgtaca attgaataat
    12601 tcttttattc aaaatgaata ccaacgtcgt cgctacctga tgaaagaacg acaaaaacgg
    12661 aatcgtttta tgggaggggt attgattttg attatgctat tatttatctt gccaactttt
    12721 aatttagcgc agagttatca gcaattactc caaagacgtc agcaattagc agacttgcaa
    12781 actcagtatc aaactttgag tgatgaaaag gataaggaga cagcatttgc taccaagttg
    12841 aaagatgaag attatgctgc taaatataca cgagcgaagt actattattc taagtcgagg
    12901 gaaaaagttt atacgattcc tgacttgctt caaaggtgat aaaatggaaa atttattaga
    12961 cgtaatagag caatttttga gtttgtcaga tgaaaagctg gaagaattgg ctgataaaaa
    13021 tcaattattg cgtttacaag aagaaaagga aaggaagaat gcgtaaattc ttaattattt
    13081 tgttgctacc aagttttttg accatttcaa aagtcgttag cacagaaaaa gaagtcgtct
    13141 atacttcgaa agaaatttat tacctttcac aatctgactt tggtatttat tttagagaaa
    13201 aattaagttc tcccatggtt tatggagagg ttcctgttta tgcgaatgaa gatttagtag
    13261 tggaatctgg gaaattgact cccaaaacaa gttttcaaat aaccgagtgg cgcttaaata
    13321 aacaaggaat tccagtattt aagctatcaa atcatcaatt tatagctgcg gacaaacgat
    13381 ttttatatga tcaatcagag gtaactccaa caataaaaaa agtatggtta gaatctgact
    13441 ttaaactgta caatagtcct tatgatttaa aagaagtgaa atcatcctta tcagcttatt
    13501 cgcaagtatc aatcgacaag accatgtttg tagaaggaag agaatttcta catattgatc
    13561 aggctggatg ggtagctaaa gaatcaactt ctgaagaaga taatcggatg agtaaagttc
    13621 aagaaatgtt atctgaaaaa tatcagaaag attctttctc tatttatgtt aagcaactga
    13681 ctactggaaa agaagctggt atcaatcaag atgaaaagat gtatgcagcc agcgttttga
    13741 aactctctta tctctattat acgcaagaaa aaataaatga gggtctttat cagttagata
    13801 cgactgtaaa atacgtatct gcagtcaatg attttccagg ttcttataaa ccagagggaa
    13861 gtggtagtct tcctaaaaaa gaagataata aagaatattc tttaaaggat ttaattacga
    13921 aagtatcaaa agaatctgat aatgtagctc ataatctatt gggatattac atttcaaacc
    13981 aatctgatgc cacattcaaa tccaagatgt ctgccattat gggagatgat tgggatccaa
    14041 aagaaaaatt gatttcttct aagatggccg ggaagtttat ggaagctatt tataatcaaa
    14101 atggatttgt gctagagtct ttgactaaaa cagattttga tagtcagcga attgccaaag
    14161 gtgtttctgt taaagtagct cataaaattg gagatgcgga tgaatttaag catgatacgg
    14221 gtgttgtcta tgcagattct ccatttattc tttctatttt cactaagaat tctgattatg
    14281 atacgatttc taagatagcc aaggatgttt atgaggttct aaaatgaggg aaccagattt
    14341 tttaaatcat tttctcaaga agggatattt caaaaagcat gctaaggcgg ttctagctct
    14401 ttctggtgga ttagattcca tgtttctatt taaggtattg tctacttatc aaaaagagtt
    14461 agagattgaa ttgattctag ctcatgtgaa tcataagcag agaattgaat cagattggga
    14521 agaaaaggaa ttaaggaagt tggctgctga agcagagctt cctatttata tcagcaattt
    14581 ttcaggagaa ttttcagaag cgcgtgcacg aaattttcgt tatgattttt ttcaagaggt
    14641 catgaaaaag acaggtgcga cagctttagt cactgcccac catgctgatg atcaggtgga
    14701 aacgattttt atgcgcttga ttcgaggaac tcgcttgcgc tatctatcag gaattaagga
    14761 gaagcaagta gtcggagaga tagaaatcat tcgtcccttc ttgcattttc agaaaaaaga
    14821 ctttccatca atttttcact ttgaagatac atcaaatcag gagaatcatt attttcgaaa
    14881 tcgtattcga aattcttact taccagaatt ggaaaaagaa aatcctcgat ttagggatgc
    14941 aatcttaggc attggcaatg aaattttaga ttatgatttg gcaatagctg aattatctaa
    15001 caatattaat gtggaagatt tacagcagtt attttcttac tctgagtcta cacaaagagt
    15061 tttacttcaa acttatctga atcgttttcc agatttgaat cttacaaaag ctcagtttgc
    15121 tgaagttcag cagattttaa aatctaaaag ccagtatcgt catccgatta aaaatggcta
    15181 tgaattgata aaagagtacc aacagtttca gatttgtaaa atcagtccgc aggctgatga
    15241 aaaggaagat gaacttgtgt tacactatca aaatcaggta gcttatcaag gatatttatt
    15301 ttcttttgga cttccattag aaggtgaatt aattcaacaa atacctgttt cacgtgaaac
    15361 atccatacac attcgtcatc gaaaaacagg agatgttttg attaaaaatg ggcatagaaa
    15421 aaaactcaga cgtttattta ttgatttgaa aatccctatg gaaaagagaa actctgctct
    15481 tattattgag caatttggtg aaattgtctc aattttggga attgcgacca ataatttgag
    15541 taaaaaaacg aaaaatgata taatgaacac tgtactttat atagaaaaaa tagataggta
    15601 aaaaatgtta gaaaacgata ttaaaaaagt cctcgtttca cacgatgaaa ttacagaagc
    15661 agctaaaaaa ctaggtgctc aattaactaa agactatgca ggaaaaaatc caatcttagt
    15721 tgggatttta aaaggatcta ttccttttat ggctgaattg gtcaaacata ttgatacaca
    15781 tattgaaatg gacttcatga tggtttctag ctaccatggt ggaacagcaa gtagtggtgt
    15841 tatcaatatt aaacaagatg tgactcaaga tatcaaagga agacatgttc tatttgtaga
    15901 agatatcatt gatacaggtc aaactttgaa gaatttgcga gatatgttta aagaaagaga
    15961 agcagcttct gttaaaattg caaccttgtt ggataaacca gaaggacgtg ttgtagaaat
    16021 tgaggcagac tatacttgct ttactatccc aaatgagttt gtagtaggtt atggtttaga
    16081 ctacaaagaa aattatcgta atcttcctta tattggagta ttgaaagagg aagtgtattc
    16141 aaattagaaa gaataatctt taatgaaaaa acaaaataat ggtttaatta aaaatccttt
    16201 tctatggtta ttatttatct ttttccttgt gacaggattc cagtatttct attctgggaa
    16261 taactcagga ggaagtcagc aaatcaacta tactgagttg gtacaagaaa ttaccgatgg
    16321 taatgtaaaa gaattaactt accaaccaaa tggtagtgtt atcgaagttt ctggtgtcta
    16381 taaaaatcct aaaacaagta aagaagaaac aggtattcag tttttcacgc catctgttac
    16441 taaggtagag aaatttacca gcactattct tcctgcagat actaccgtat cagaattgca
    16501 aaaacttgct actgaccata aagcagaagt aactgttaag catgaaagtt caagtggtat
    16561 atggattaat ctactcgtat ccattgtgcc atttggaatt ctattcttct tcctattctc
    16621 tatgatggga aatatgggag gaggcaatgg ccgtaatcca atgagttttg gacgtagtaa
    16681 ggctaaagca gcaaataaag aagatattaa agtaagattt tcagatgttg ctggagctga
    16741 ggaagaaaaa caagaactag ttgaagttgt tgagttctta aaagatccaa aacgattcac
    16801 aaaacttgga gcccgtattc cagcaggtgt tcttttggag ggacctccgg ggacaggtaa
    16861 aactttgctt gctaaggcag tcgctggaga agcaggtgtt ccattcttta gtatctcagg
    16921 ttctgacttt gtagaaatgt ttgtcggagt tggagctagt cgtgttcgct ctctttttga
    16981 ggatgccaaa aaagcagcac cagctatcat ctttatcgat gaaattgatg ctgttggacg
    17041 tcaacgtgga gtcggtctcg gcggaggtaa tgacgaacgt gaacaaacct tgaaccaact
    17101 tttgattgag atggatggtt ttgagggaaa tgaagggatt atcgtcatcg ctgcgacaaa
    17161 ccgttcagat gtacttgacc ctgccctttt gcgtccagga cgttttgata gaaaagtatt
    17221 ggttggtcgt cctgatgtta aaggtcgtga agcaatcttg aaagttcacg ctaagaataa
    17281 gcctttagca gaagatgttg atttgaaatt agtggctcaa caaactccag gctttgttgg
    17341 tgctgattta gagaatgtct tgaatgaagc agctttagtt gctgctcgtc gcaataaatc
    17401 gataattgat gcttcagata ttgatgaagc agaagataga gttattgctg gaccttctaa
    17461 gaaagataag acagtttcac aaaaagaacg agaattggtt gcttaccatg aggcaggaca
    17521 taccattgtt ggtctagtct tgtcgaatgc tcgcgttgtc cataaggtta caattgtacc
    17581 acgcggccgt gcaggcggat acatgattgc acttcctaaa gaggatcaaa tgcttctatc
    17641 taaagaagat atgaaagagc aattggctgg cttaatgggt ggacgtgtag ctgaagaaat
    17701 tatctttaat gtccaaacca caggagcttc aaacgacttt gaacaagcga cacaaatggc
    17761 acgtgcaatg gttacagagt acggtatgag tgaaaaactt ggcccagtac aatatgaagg
    17821 aaaccatgct atgcttggtg cacagagtcc tcaaaaatca atttcagaac aaacagctta
    17881 tgaaattgat gaagaggttc gttcattatt aaatgaggca cgaaataaag ctgctgaaat
    17941 tattcagtca aatcgtgaaa ctcacaagtt aattgcagaa gcattattga aatacgaaac
    18001 attggatagt acacaaatta aagctcttta cgaaacagga aagatgcctg aagcagtaga
    18061 agaggaatct catgcactat cctatgatga agtaaagtca aaaatgaatg acgaaaaata
    18121 accctgagag aggctggagc
//
LOCUS       DAVFER010000042        18093 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1105170250
            SAMEA2167659-rid19724873.denovo.042, whole genome shotgun sequence.
ACCESSION   DAVFER010000042 DAVFER010000000
VERSION     DAVFER010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2167659
            Sequence Read Archive: ERR388902
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18093)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18093)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928716.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928716.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 04:07:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,118
            CDSs (total)                      :: 2,073
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 120
            CDSs (without protein)            :: 120
            Pseudo Genes (ambiguous residues) :: 0 of 120
            Pseudo Genes (frameshifted)       :: 67 of 120
            Pseudo Genes (incomplete)         :: 47 of 120
            Pseudo Genes (internal stop)      :: 34 of 120
            Pseudo Genes (multiple problems)  :: 23 of 120
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18093
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2167659-rid19724873.denovo.042"
                     /strain="1105170250"
                     /db_xref="taxon:1313"
     gene            complement(114..1964)
                     /locus_tag="VU534_001604"
     CDS             complement(114..1964)
                     /locus_tag="VU534_001604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HEU1514164.1"
                     /translation="MNKKLTDYVIDLVEILNKQQKQVFWGIFDIFSMVVSIIVSYILF
                     YGLINPAPVDYIIYTSLAFLFYQLMIGFWGLNASISRYSKITDFMKIFFGVTASSVLS
                     YSICYAFLPLFSIRFIILFILLSTFLILLPRITWQLIYSRRKKGSGDGEHRRTFLIGA
                     GDGGALFMDSYQHPTSELELVGILDKDSKKKGQKLGGIPVLGSYDNLPELAKRHQIER
                     VIVAIPSLDPSEYERILQMCNKLGVKCYKMPKVETVVQGLHQAGTGFQKIDITDLLGR
                     QEIRLDESRLGAELTGKTILVTGAGGSIGSEICRQVSRFNPERIVLLGHGENSIYLVY
                     HELIRKFQGIDYVPVIADIQDYDRLLQVFEQYKPAIVYHAAAHKHVPMMERNPKEAFK
                     NNIRGTYNVAKAVDEAKVSKMVMISTDKAVNPPNVMGATKRVAELIVTGFNQRSQSTY
                     CAVRFGNVLGSRGSVIPVFERQIAEGGPVTVTDFRMTRYFMTIPEASRLVIHAGAYAK
                     DGEVFILDMGKPVKIYDLAKKMVLLSGHTESEIPIVEVGIRPGEKLYEELLVSTELVD
                     NQVMDKIFVGKVNVMPLESINQKIGEFRTLSGDELKQAIIAFANQTTHIE"
     gene            complement(2006..3163)
                     /locus_tag="VU534_001605"
     CDS             complement(2006..3163)
                     /locus_tag="VU534_001605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000096189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEU1514165.1"
                     /translation="MSSKVSGFQDKNGKVLKIMIEWWKEKFRRVVVTQNVESLLVSIV
                     ISAYNEEKYLPGLIEDLKNQTYPKEDIEILFINAMSTDGTTAIIQQFIKEDTEFNSIR
                     LYNNPKKNQASGFNLGVKHSVGDLILKIDAHSKVTETFVMNNVAIIQQGEFVCGGPRP
                     TIVEGKGKWAETLHLVEENMFGSSIANYRNSSEDRYVSSIFHGMYKREVFQKVGLVNE
                     QLGRTEDNDIHYRIREYGYKIRYSPSILSYQYIRPTFKKMLHQKYSNGLWIGLTSHVQ
                     FKCLSLFHYVPCLFVLSLVFSLALLPITFVFITLLLGAYFLLLSLLTLLTLLKHKNGF
                     LIVMPFILFSIHFAYGLGTIVGLIRGFKWKKEYKRTIIYLDKISQINQNML"
     gene            3221..4387
                     /locus_tag="VU534_001606"
     CDS             3221..4387
                     /locus_tag="VU534_001606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CynX/NimT family MFS transporter"
                     /protein_id="HEU1514166.1"
                     /translation="MKKQSLFFVPGIILIGVSLRTPFTVLPIILGNISQGLEVEVSSL
                     GVLTSLPLLMFTLFSPFSTQLAQKIGLEHLFTYSLFFLTIGSLIRLINLPLLYLGTLM
                     VGASVAVINVLLPSLIQANQPKKIGFLTTLYVTSMGIATALASYLAVPITQASSWKGL
                     ILLLTLLCLATFLVWLPNHRYNHRLAPQTKQKSQIKVMRNKQVWAIIIFSGFQSLIFY
                     TVMTWLPTMSIHAGLSSHEAGLLTSILSLISIPFSMTIPSLTTSLSTRNRQLMLTLVS
                     LAGVVGISMLFFPINNFIYWLAIHLLIGTATSALFPYLMVNFSLKTSAPEKTAQLSGL
                     SQTGGYILAAFGPTLFGYSFDLFHSWVPSVAALLLIDILMTVALFTVDRADKIL"
     gene            4526..4852
                     /locus_tag="VU534_001607"
     CDS             4526..4852
                     /locus_tag="VU534_001607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000273865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HEU1514167.1"
                     /translation="MYFPTSSALIEFLILAVLEQGDSYGYEISQTIKLIANIKESTLY
                     PILKKLEGNSFLTTYSREFQGRMRKYYSLTNGGIEQLLTLKDEWALYTDTINGIIEGS
                     IRHDKN"
     gene            4839..5432
                     /locus_tag="VU534_001608"
     CDS             4839..5432
                     /locus_tag="VU534_001608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000198695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HEU1514168.1"
                     /translation="MTRTEYLTQLELYLKKLPEADRIEAMDYFRELFDDAGVEGEEEL
                     IASLGTPKEAAHEVLSNLLDKKINEAPAQKNNRQILHIALLALLAAPIGIPLGIAILV
                     TLFAILVAALTVILAFFAVSILGIIGGFLFLVESFTVLAQAKSAFILIFGSGLLAIGA
                     SSLVLLGISYATRFFGLLIVRLVQFVLKKGKRGNQHA"
     gene            5425..6336
                     /locus_tag="VU534_001609"
     CDS             5425..6336
                     /locus_tag="VU534_001609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001233690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 domain-containing protein"
                     /protein_id="HEU1514169.1"
                     /translation="MRKWTKGFLIFGVVTTVIGFILLFVGIQSDGIKSLLSMSKEPVY
                     DSRTEKLTFGKEVENLEITLHQHTLTITDSFDDQIHISYHPSLSAHHDLITNQNDRTL
                     SLTDKKLSETPFLSSGIGGILHIASSYSSRFEEVILRLPKGRTLKGINISANRGQTTI
                     INASLENATLNTNSYILRIEGSRIKNSKLTTPNIVNIFDTVLTDSQLESTENHFHAEN
                     IQVHGKVELTAKDYLRIILDQKESQRINWDISSNYGSIFQFTREKPESRGTELSNPYK
                     TEKTDVKDQLIARSDDNIDLISTPSRR"
     gene            6399..7463
                     /locus_tag="VU534_001610"
     CDS             6399..7463
                     /locus_tag="VU534_001610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1514170.1"
                     /translation="MKQEWFESNDFVKTTSKNKPEEQAQEVADKAEETIADLDTPIEK
                     NTQLEEEVPQAEVELESQQEEKIEAPEDSEARTEIEEKKASNSTEEEPDLSKETEKVT
                     IAEESQEALPQQKATTKEPLLISKSLESPYIPDQAPKSRDKWKEQVLDFWSWLVEAIK
                     SPTSKLETSITHSYTAFLLLILFSASSFFFSIYHIKHAYYGHIASINSRFPEQLAPLT
                     LFSIISILVATTLFFFSFLLGSFVVRRFIHQEKDWTLDKVLQQYSQLLAIPIFLTAIA
                     SFFAFFDSLRFTALLCVISIGIILLASLHIITRPSQASETDSFYQLFLSVLVNGVIIL
                     LFFVAEVALIGDYLRILAFL"
     gene            complement(7641..8501)
                     /locus_tag="VU534_001611"
     CDS             complement(7641..8501)
                     /locus_tag="VU534_001611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4299 domain-containing protein"
                     /protein_id="HEU1514171.1"
                     /translation="MAKTFFIPNKQSILGEQEILNAKSILALLDGLESHSYDVVYLRQ
                     PLNRLEYIECAIVGQSQFLFKVSYADGQKAYRVDLPDLLTKTDWQIIKSFLDALLAYT
                     GTDIEGLDGFDFEAYFQASIQAYLADPVARFTICQGIFNPIFFSRENLKSFLEADGLA
                     QFEARVRAVQETDAYFARVSFYQDGEGKVHGVYHLAQGVKTVLPREPFVPAAYIEQLV
                     DKEVQWEIDLVQITGDGSKPEDYEAIARLDYAKFLEVLPPSFYHQLDANQIEVQPILD
                     KDFKTLAQEK"
     gene            complement(8776..9762)
                     /locus_tag="VU534_001612"
     CDS             complement(8776..9762)
                     /locus_tag="VU534_001612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001030014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-related sulfurtransferase"
                     /protein_id="HEU1514172.1"
                     /translation="MAKDIRVLLYYLYTPIENAEQFAADHLAFCKSIGLKGRILVADE
                     GINGTVSGDYETTQKYMDYVHSLPGMEELWFKIDEENEQAFKKMFVRYKKEIVHLGLE
                     DNDFDNDINPLETTGAYLSPKEFKEALLDKDTVVLDTRNDYEYDLGHFRGAIRPDIRN
                     FRELPQWVRDNKEKFMDKRVVVYCTGGVRCEKFSGWMVREGYKDVGQLHGGIATYGKD
                     PEVQGELWDGKMYVFDERIAVDVNHVNPTIVGKDWFDGTPCERYVNCGNPFCNRRILT
                     SEENEDKYLRGCSHECRVHPRNRYVSKNELTQAEVIERLAAIGESLDQAATV"
     gene            complement(10034..11509)
                     /locus_tag="VU534_001613"
     CDS             complement(10034..11509)
                     /locus_tag="VU534_001613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3502 domain-containing protein"
                     /protein_id="HEU1514173.1"
                     /translation="MKNWKKYAFASASVVALAAGLAACGNLTGNSKKAADSGDKPVIK
                     MYQIGDKPDNLDELLANANKIIEEKVGAKLDIQYLGWGDYGKKMSVITSSGENYDIAF
                     ADNYIVNAQKGAYADLTELYKKEGKDLYKALDPAYIKGNTVNGKIYAVPVAANVASSQ
                     NFAFNGTLLAKYGIDISGVTSYETLEPVLKQIKEKAPDVVPFAIGKVFIPSDNFDYPV
                     ANGLPFVIDLEGDTTKVVNRYEVPRFKEHLKTLHKFYEAGYIPKDVATSDTSFDLQQD
                     TWFVREETVGPADYGNSLLSRVANKDIQIKPITNFIKKNQTTQVANFVISNNSKNKEK
                     SMEILNLLNTNPELLNGLVYGPEGKNWEKIEGKENRVRVLDGYKGNTHMGGWNTGNNW
                     ILYINENVTDQQIENSKKELAEAKESPALGFIFNTDNVKSEISAIANTMQQFDTAINT
                     GTVDPDKAIPELMEKLKSEGAYEKVLNEMQKQYDEFLKNKK"
     gene            complement(11767..12690)
                     /locus_tag="VU534_001614"
     CDS             complement(11767..12690)
                     /locus_tag="VU534_001614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001075101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEU1514174.1"
                     /translation="MAKKKIKKEKIDNVGIHSFSKKADIFFSIISGLIALSCILPFVF
                     VIIISVTDEKSLLQYGYSFFPSQFGLDGFEFLAQFKDKILQALFISVFVTVVGTLTNV
                     FITTTYAYAISRTTFKYRRFFTIFVLLSMLFNAGLVPGYIMVTRVLQLGDTVWALIVP
                     MLLSPFNIILMRSFFKKTIPEAILESARIDGASEARIFFQICLPLSLPGIATITLLTA
                     LGFWNDWFNALLYIKSDNLYPLQYLLMQIQQNMDYIAKAVGLIGQLGVALPKETGRMA
                     MVVVATLPIAILYPFFQRYFVKGLTIGGVKE"
     gene            complement(12704..13633)
                     /locus_tag="VU534_001615"
     CDS             complement(12704..13633)
                     /locus_tag="VU534_001615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEU1514175.1"
                     /translation="MKKFSKTLRDNWIFLLMVLPGALWLILFFYIPVFGNVVAFKDYH
                     MTSNGFIDSIINSKWVGLDNFRFLFSSRDAFIITRNTVLYNLGFIFLGLVVSVGIAII
                     LSELRSKRMVKIFQTSMLFPYFLSWVIISFFTDAFLNIDKGVFNHLLESLGLKEVNFY
                     ADLGIWPYLLLFLGIWKGFGYSSVMYYATIMGIDPTYYEAATVDGASKWQRIRNVTIP
                     QLTPLVTVLTILAVGNIFRADFGLFYQIPHNAGQLYNVTNVLDVYVFNGLTQTADIGM
                     AAAAGLYQSVVGLILVILSNLLARRVDPNSALF"
     gene            complement(13952..14173)
                     /locus_tag="VU534_001616"
     CDS             complement(13952..14173)
                     /locus_tag="VU534_001616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1514176.1"
                     /translation="MSLQIKLKKLAKELSKLLKDSNLETVDKDVLENSQKELQKAVLF
                     LADEKGSEHTAAELIDNLKEVIAKLKANA"
     gene            complement(14127..14387)
                     /locus_tag="VU534_001617"
     CDS             complement(14127..14387)
                     /locus_tag="VU534_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1514177.1"
                     /translation="MTGVSNPTTDSARLVLAEANKAFADDSLTEQGLRDILQTVKDAI
                     ASLESIKESQSATKDGGQTAGKETAGEDESANQTQEISQGIK"
     gene            14467..14604
                     /locus_tag="VU534_001618"
                     /pseudo
     CDS             14467..14604
                     /locus_tag="VU534_001618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            complement(14708..14863)
                     /locus_tag="VU534_001619"
                     /pseudo
     CDS             complement(14708..14863)
                     /locus_tag="VU534_001619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            complement(15041..15652)
                     /gene="rpsD"
                     /locus_tag="VU534_001620"
     CDS             complement(15041..15652)
                     /gene="rpsD"
                     /locus_tag="VU534_001620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HEU1514178.1"
                     /translation="MSRYTGPSWKQARRLGLSLTGTGKELARRNYVPGQHGPNNRSKL
                     SEYGLQLAEKQKLRFTYGVGEKQFRNLFVQATKIKGGILGFNFMLLLERRLDNVVYRL
                     GLATTRRQARQFVNHGHILVDGKRVDIPSYRVTPGQVISVREKSLKVPAILEAVEATL
                     GRPAFVSFDAEKLEGSLTRLPERDEINPEINEALVVEFYNKML"
     gene            complement(15847..16899)
                     /locus_tag="VU534_001621"
     CDS             complement(15847..16899)
                     /locus_tag="VU534_001621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000769768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HEU1514179.1"
                     /translation="MKLKSYILVGYIISTLLTILVVFWAVQKMLIAKGEIYFLLGMTI
                     VASLVGAGISLFLLLPVFTSLGKLKEHAKRVAAKDFPSNLEVQGPVEFQQLGQTFNEM
                     SHDLQVSFDSLEESEREKGLMIAQLSHDIKTPITSIQATVEGILDGIIKESEQAHYLA
                     TIGRQTERLNKLVEELNFLTLNTARNQVETTSKDSIFLDKLLIECMSEFQFLIEQERR
                     DVHLQVIPESARIEGDYAKLSRILVNLVDNAFKYSAPGTKLEVVAKLEKDQLSISVTD
                     EGQGIAPEDLENIFKRLYRVETSRNMKTGGHGLGLAIARELAHQLGGEITVSSQYGLG
                     STFTLVLNLSGSENKA"
     gene            complement(16896..17594)
                     /locus_tag="VU534_001622"
     CDS             complement(16896..17594)
                     /locus_tag="VU534_001622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000520636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU1514180.1"
                     /translation="MGKTILLVDDEVEITDIHQRYLIQAGYQVLVAHDGLEALELFKK
                     KPIDLIITDVMMPRMDGYDLISEVQYLSPEQPFLFITAKTSEQDKIYGLSLGADDFIA
                     KPFSPRELVLRVHNILRRLHRGGETELISLGNLKMNHSSHEVQIGEEMLDLTVKSFEL
                     LWILASNPERVFSKTDLYEKIWKEDYVDDTNTLNVHIHALRQELAKYSSDQTPTIKTV
                     WGLGYKIEKPRGQT"
     gene            complement(17761..>18093)
                     /locus_tag="VU534_001623"
     CDS             complement(17761..>18093)
                     /locus_tag="VU534_001623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEU1514181.1"
                     /translation="INVKETSDTANGSLSPSNSGSGVTPMNHNHATGTTDSMPADTMT
                     SSTNTMAGENMAASANKMSDTMMSEDKAMLPNTGETQTSMASIGFLGLALAGLLGGLG
                     LKNKKEEN"
BASE COUNT         5339 a         3905 c         3356 g         5493 t
ORIGIN      
        1 acggcaaggc gacgttgacg tggtttgaag agattttcga agagtataag tctctacata
       61 ataaaacgca tattaccaag gttgtgtaac ttgatactat gcgtttttct tttttattca
      121 atgtgggttg tttgattagc aaaggcgata atagcttgct tcaactcatc tccactgaga
      181 gtgcggaact ctccaatctt ttgattgatg gattctaaag gcatgacatt aaccttacca
      241 acgaaaatct tatccataac ttgattatca acgagttcgg ttgataccaa gagttcttcg
      301 tagagttttt cacctgggcg gattccaact tcaacgattg gaatttcact ttcagtgtgg
      361 ccacttagaa gcaccatctt cttggccaag tcataaatct tgactggttt gcccatatca
      421 aggataaaga cttccccatc tttggcataa gcaccagcat ggataaccag acggctagct
      481 tctggaatgg tcataaagta acgggtcata cggaagtctg tcaccgttac aggcccacct
      541 tcagcaatct gacgttcaaa gactggaatg acactaccac ggctaccaag aacattccca
      601 aaacgaactg cacagtaggt tgattggcta cgttggttaa agccagtgac aatcaactcc
      661 gccacgcgct tggttgctcc cataacattt ggtggattga ctgccttatc tgtcgaaatc
      721 ataaccatct tagacacttt agcttcatca acagccttag caacattgta agttccacgg
      781 atattgtttt tgaaggcttc ttttggattg cgctccatca taggaacatg cttgtgggct
      841 gccgcatgat aaacaatagc aggtttgtac tgctcaaaga cttgcaacaa acgatcatag
      901 tcttgaatgt ccgcaatcac aggtacataa tcaatccctt ggaacttacg aatcaattca
      961 tgataaacaa ggtagattga gttttcccca tgaccgagca agacaatgcg ttcaggattg
     1021 aagcgactaa cttgacgaca gatttcagaa ccgattgaac ctccagctcc tgtgactaag
     1081 atggtcttac ctgtcagttc tgcacccaga cgcgattcgt caagacggat ttcctgacga
     1141 cccaaaaggt ccgtaatatc aattttttgg aagccagtac ctgcttggtg aaggccctga
     1201 acaacagttt caaccttagg catcttgtaa catttgacac ccagcttatt acacatctgc
     1261 aagatacgct catattctga cggatccagc gacggaatcg caacgatgac acgctcgatt
     1321 tgatggcgtt tggctaattc aggcagattg tcataagagc ccaaaacagg aataccacca
     1381 agtttttgac cctttttctt agaatcctta tccaaaatac cgaccagttc taattcactg
     1441 gttggatgtt ggtaactatc cataaaaaga gccccaccat caccggcacc aatcaagaag
     1501 gtccgacggt gttctccatc accactacct tttttgcgtc tggagtagat taactgccaa
     1561 gtaatccgtg gcaataaaat caagaaggta ctcaacaaga taaagagaat gatgaaacgg
     1621 atggagaaga gtggcaagaa ggcataacag atactatatg acaagacact gctagcagtc
     1681 acaccaaaaa agattttcat gaaatccgta atcttgctgt aacgactaat gctcgcgttc
     1741 aacccccaaa aaccaatcat caattgatag aacaggaagg ccaaactcgt atagataatg
     1801 tagtcaacag gtgctggatt aatcagccca taaaataaaa tataagatac aatgatggaa
     1861 accaccatac tgaaaatatc aaatattccc cagaaaacct gcttttgttg tttatttaaa
     1921 atttccacca gatcaatcac ataatctgtt agttttttat tcatagaaat ctactcctcc
     1981 ttaaaagagt tttactatat tgttattata gcatattttg atttatttgg cttattttat
     2041 ccaaataaat tattgttctc ttgtactcct tcttccattt aaatcctcta attaaaccta
     2101 caatcgtccc aaggccataa gcaaagtgaa tggaaaataa aataaagggc atcacaatta
     2161 gaaatccatt tttatgtttt aataaagtca gcaaagtgag taatgacaaa agtagaaaat
     2221 aggcacctaa tagtaaagtt atgaatacga atgtgatcgg taacaatgct agactaaaca
     2281 caagactcaa aacaaataaa caaggaacat agtgaaataa tgataaacac ttaaactgaa
     2341 catgacttgt caagccaatc cacaaaccat ttgaatactt ttgatgcagc attttcttga
     2401 atgttggtcg aatatactga taagatagaa tacttgggct atagcggatt ttataaccat
     2461 attctcgaat tctataatga atatcattat cttcagttcg gccaagttgc tcatttacta
     2521 aaccaacctt ctggaaaacc tctcgtttat acattccatg aaaaatagaa gaaacatatc
     2581 tatcctcaga actatttcga taattggcaa tgctactgcc aaacatattt tcctcaacaa
     2641 gatgcaaggt ctctgcccat tttccttttc cttcgacaat cgtcggtcta ggccccccac
     2701 agacaaattc accttgttga ataatagcca cattgttcat tacaaaagtc tcagtaactt
     2761 ttgaatgagc atcaattttt aaaataaggt cccctacaga atgtttaact cccaggttaa
     2821 aaccactagc ttgatttttc ttaggattgt tatacaatct aattgagtta aactctgtat
     2881 cttcctttat aaattgctga atgatagctg tggtcccatc tgtggacata gcatttataa
     2941 atagaatttc aatatcctct ttaggatagg tttgattttt taagtcttca attagaccag
     3001 gcagatattt ttcttcattg tatgcactga ttacaatgga tacgagaaga ctttcaacat
     3061 tttgagtcac tactactctc ctgaattttt ccttccacca ttctatcata attttcaaga
     3121 ctttcccatt tttatcttga aagccagaaa ccttacttga cattatagtg aaaaagcctt
     3181 aaaataagct gttattaaaa tcagctagaa gaggtattat atgaaaaagc aatcactctt
     3241 ttttgttcca ggtattatcc tgattggtgt ttccttgcga actcctttta ctgttttacc
     3301 cattattttg ggaaatattt cgcaaggtct ggaggtagaa gttagttcgc ttggtgtctt
     3361 gaccagcctg cctctcctta tgtttaccct cttttcacca ttttctaccc aactggctca
     3421 gaaaatcggc ttggagcatc tcttcaccta cagcctcttc ttcttgacca tcggctcact
     3481 tattcgacta atcaatctgc ccctgctcta tctaggaacc ttgatggttg gggcaagtgt
     3541 cgcagtcatc aatgtcctgc ttcctagtct tatccaagcc aatcaaccaa agaaaattgg
     3601 ttttctgacc accttatatg taacgtctat ggggattgca acggctctgg cttcctatct
     3661 agctgtgccc attacacaag ccagttcttg gaaaggactt atccttctcc tcacgttact
     3721 ctgtctagca acttttttgg tctggctccc aaatcaccgc tataatcata gactagctcc
     3781 acaaaccaaa caaaaaagtc aaataaaggt catgcgtaat aaacaggttt gggcaattat
     3841 tatcttttca ggttttcaat ccttgatctt ttacaccgtc atgacctggt tacctaccat
     3901 gtctatccat gcaggtctat ccagtcacga agctggcttg ctgacttcta tcttatctct
     3961 gattagcatt cctttttcaa tgaccatccc aagcctgaca accagtttat ctactcgcaa
     4021 ccgtcagctc atgctcactc tggtttcact agctggtgtg gtcggcattt ccatgctctt
     4081 tttcccaatc aataatttca tttactggct tgccatccat ctcctcatcg gaaccgcaac
     4141 cagtgccctc ttcccttatc tcatggtcaa cttttcactc aagacaagcg cccctgaaaa
     4201 gacagcccaa ttgtccggcc tatctcaaac aggaggctat atcctagcag cctttgggcc
     4261 aaccctcttt ggttacagtt ttgacctgtt ccactcttgg gtaccatctg tagctgccct
     4321 cttgctcatc gatatcctga tgactgtggc cctctttaca gtggacagag cggataagat
     4381 cctttaaact tctagtttta gctagaagtt ttttatatat aaaaatttta cacatttctc
     4441 ttgacagggc tttcttttag atgtacaatg tatgtgtaga aaaattatat ataaaaatct
     4501 tacacattag aaaaggaggt ttcccatgta ctttccaaca tcctctgcct tgattgaatt
     4561 tctcatcttg gctgtactgg agcagggtga ttcttatggt tatgagatta gccaaaccat
     4621 taagctgatc gctaatatca aagaatccac actctatccc attctcaaaa aattggaagg
     4681 caatagcttt ctgacaacct attctagaga gttccaaggt cgcatgcgca aatactactc
     4741 cttgacaaac ggtggtatag agcagctctt gaccctaaaa gatgaatggg cactctatac
     4801 agacaccatc aatggcatca tagaagggag tatccgccat gacaagaact gaatacctga
     4861 ctcagctaga actctatctc aagaaactac ctgaagctga ccgtatcgaa gccatggact
     4921 atttcagaga gctctttgac gatgctggag tcgaaggaga agaagaactc atcgctagtt
     4981 tgggaactcc caaagaagcg gcccacgaag ttctatccaa tcttctcgat aaaaaaatca
     5041 atgaagcacc cgctcaaaaa aataaccgac aaattttaca tatcgccttg ttagccctcc
     5101 ttgcagcacc tatcggcatt cctctgggaa tcgccatcct cgtgaccctg ttcgcaattc
     5161 ttgtagccgc tttgactgtc attctggctt tctttgcagt ttccatactg ggtatcatcg
     5221 gcggattcct atttttagtt gaaagtttca ctgtcctcgc ccaagccaaa tcagccttta
     5281 tcttgatttt tggttctggt ttactggcta tcggtgcttc ttcgctagtt ttacttggca
     5341 tttcctatgc aactcgcttc ttcggtctac tcattgttcg tctggtacaa tttgttctta
     5401 aaaaaggaaa gagaggtaat cagcatgcgt aaatggacaa aaggatttct catctttggt
     5461 gtggtgacta ccgttatcgg ctttatcctg ctttttgtag gtatccaatc tgacgggatt
     5521 aagagcctac tttccatgtc caaagaacct gtctatgata gccgtacgga aaagctaacc
     5581 tttggcaagg aagtcgaaaa cctagaaatt actctccacc aacacacgct caccatcaca
     5641 gactctttcg atgatcaaat ccacatttct taccatccat ctctttctgc tcaccatgat
     5701 cttatcacca atcagaacga tagaactctg agtctcactg ataagaaact gtctgaaact
     5761 ccgtttctct cttctggaat tggtgggatt cttcatatcg caagtagcta ctctagtcgt
     5821 tttgaagaag ttattctccg actaccaaaa gggagaactc taaaagggat caacatctca
     5881 gccaatcgcg gacaaaccac catcataaat gctagccttg aaaatgcgac cctcaataca
     5941 aacagctata tcctccgaat tgaaggaagt cgtatcaaaa acagtaaact cacaacgccc
     6001 aatatcgtta atatctttga tacagttctt acagatagtc agctagagtc aacagagaat
     6061 cacttccacg ctgaaaatat ccaagtccat ggcaaggttg aactgactgc caaagattat
     6121 ctcagaatca tcctagacca gaaagaaagc caacgaatta actgggacat ctcaagcaac
     6181 tatggttcta tcttccaatt cacaagagaa aagcctgaat caagaggtac ggaattaagc
     6241 aacccttaca aaactgaaaa aaccgatgtc aaggatcaac tcattgcgag atctgatgat
     6301 aatattgatc taatatccac accaagcaga cgttgacaaa aacgcttaca tttgctacta
     6361 tggaaacata tttatctaac taaaaaggag gttctaccat gaaacaagaa tggtttgaaa
     6421 gtaatgattt tgtaaaaaca acaagcaaga acaagcctga agagcaagct caagaggttg
     6481 cagacaaggc tgaagaaacg atagccgatc tcgatacacc aattgaaaaa aatactcagt
     6541 tagaggagga agtccctcaa gctgaagtcg aattggaaag ccagcaagaa gagaaaattg
     6601 aagctcctga agacagtgaa gcgagaacag aaatagaaga aaagaaggca tctaattcta
     6661 ctgaagaaga gccagacctt tctaaagaaa cagaaaaagt cactatagct gaagagagcc
     6721 aagaagctct tcctcagcaa aaagcaacca cgaaagagcc acttcttatc agtaaatctt
     6781 tagaaagtcc ttatatcccc gaccaagctc caaaatctag ggataaatgg aaagagcaag
     6841 tgcttgattt ttggtcttgg ctagtggaag cgatcaaatc tcctacaagt aagttggaaa
     6901 caagtatcac acacagttac acagcctttc tcttgctcat tctgttttct gcatcttcct
     6961 ttttctttag tatctatcac atcaaacatg cttactatgg acatatagca agcattaaca
     7021 gtcgcttccc tgagcagcta gctcctttaa ctcttttttc tatcatctct atcctagtag
     7081 cgacaacact cttcttcttt tcattcctct tgggtagttt cgttgtgaga cgatttatcc
     7141 accaggaaaa ggactggacg ctagacaagg ttctccaaca atatagtcaa ctcttggcaa
     7201 ttccaatctt cctcactgct attgctagtt tctttgcttt ctttgatagc ctacgattta
     7261 cagccctctt gtgtgtgatt agcattggaa tcattctgct tgccagtctc catatcatta
     7321 caagaccaag tcaagcaagt gaaaccgact ccttctatca attattcttg tctgtccttg
     7381 tgaacggagt tattatcctc ctcttctttg tagctgaagt ggcactgatt ggagattatc
     7441 ttcgtatctt ggcctttctt taaacttcat actcttcaaa aatcaaattc aaaccacgtc
     7501 agcttcgcct taccgtactc aagtacagcc tgcggctagc ttcctagttt gctctttgat
     7561 tttcattgag tagcaatcct gtcatccttg gcaggatttt ttctatgtca aaaaagcaag
     7621 tcgattgacc tgcttctgct ttacttttct tgtgctaatg ttttaaaatc tttgtctaat
     7681 atgggttgca cttctatttg attggcgtct agttggtggt aaaaagatgg gggtaatacc
     7741 tctaagaatt ttgcatagtc caagcgagca atggcttcat agtcttctgg tttagagcca
     7801 tctcctgtga tttgaaccaa gtcaatctcc cactggactt ccttatccac caattgctca
     7861 atataggctg caggaacaaa cggttctctc ggtaaaactg tcttgactcc ttgagctaga
     7921 tggtaaacgc catgcacttt tccttctcca tcctgataga aggaaactct cgcaaagtag
     7981 gcatctgtct cttgaaccgc acgcacacgc gcttcaaact gagccaagcc atctgcctct
     8041 aaaaagcttt tcaagttctc acgactaaag aaaataggat taaaaattcc ttggcaaatc
     8101 gtaaaacgag ctacagggtc tgctagatag gcttgaatac ttgcttggaa ataagcttca
     8161 aaatcaaaac catctagccc ttcaatatca gtccctgtat aagcaagcaa agcatctaaa
     8221 aatgacttga taatctgcca gtctgtcttt gttagtaggt caggaagatc gacacggtaa
     8281 gccttttgac catcagcata actgacctta aagagaaatt gtgattgccc cactatcgca
     8341 cactcgatat attcgagacg attaagaggc tgacggagat agactacatc atagctatgt
     8401 gactccaaac cgtctagcaa ggccaagatc gacttggcat tcaaaatctc ttgttctcct
     8461 aaaatgctct gtttatttgg aataaaaaat gttttcgcca taactggact cctttgaaat
     8521 cgtttacata cagtatacct tatttttctg aaagatacaa aaacaaactt tatactcttc
     8581 gaaaatctct tcaaaccgcg tcagcttcgc cttgccgtag atatatgtaa ctgacttcgt
     8641 cagtcttatc tacaacctca aagcagtgct ttgagcagcc tgcagctagc ttcctagttt
     8701 gctctttgat tttcattgag tattagattt ttgagtacaa agcatagaaa aacagcccct
     8761 gaggactgtt tgatcttata cagtagctgc ttgatccaag ctttcaccga tagcggctag
     8821 gcgctcgata acttcagctt gtgtcaattc attttttgaa acatagcggt tacgtgggtg
     8881 aacacggcac tcgtgtgagc atccacgaag gtacttgtct tcattttctt ctgatgtcaa
     8941 gatacgacgg ttacagaatg gatttccaca gttgacataa cgttcacatg gtgttccatc
     9001 aaaccagtct ttccctacga tagttgggtt gacatggttg acatcaacgg caatacgctc
     9061 gtcaaagacg tacattttcc catcccaaag ctcaccttga acttctgggt ctttaccgta
     9121 agttgcgatt cctccgtgca attggccgac atctttgtag ccttcacgga ccatccagcc
     9181 tgagaatttc tcacagcgaa cgccacctgt acagtaaacc acgacacgct tgtccatgaa
     9241 tttttccttg ttatcacgga cccattgtgg taactcacgg aagttgcgaa tatctgggcg
     9301 aatagctcca cggaaatgtc ctaggtcgta ctcataatcg ttacgtgtgt caaggacaac
     9361 ggtatcttta tcaagaagcg cttctttgaa ctcttttgga gacaagtaag cacctgttgt
     9421 ttcaagtggg ttgatgtcat tgtcaaagtc gttgtcttcc aaaccaaggt ggacaatttc
     9481 tttcttgtag cgaacaaaca tcttcttgaa ggcttgttca ttttcttcgt caatcttgaa
     9541 ccagagttct tccattcctg gaaggctgtg aacgtagtcc atgtattttt gagttgtttc
     9601 atagtcacct gaaactgttc cgttaattcc ctcgtcagcg actaggatac ggcctttaag
     9661 gccgattgat ttacagaaag ccaagtggtc tgcagcaaat tgctctgcat tttcaattgg
     9721 agtataaagg tagtaaagta agacacgaat atcttttgcc ataagatttg ttctcttttc
     9781 tattcttaaa ttttctaaat tttttattta tctacactag tatacctgct tgagaaaacg
     9841 aatgcaattt atttgactgg aaattgtaga gggttctcga aatttcttga atggttaaaa
     9901 taaggacaag agaaaacatg gatatctata tccttgtgcc aaaaaaacca ctgccctccc
     9961 cagaccaacc tgaggaaagc agtgattctt attttaggag ttaggaatga atacacgaaa
    10021 tcaatttagc tgattatttt ttgtttttca agaattcatc gtattgtttt tgcatttcgt
    10081 tcaatacttt ttcgtaggca ccttcagatt tcaatttttc catcaattct ggaatcgctt
    10141 tatctgggtc tacagtacca gtgttgatag ctgtatcaaa ttgttgcatt gtgttagcaa
    10201 tagctgagat ttcagatttc acattgtcag tattgaagat aaatccaagc gctggagatt
    10261 ctttagcttc tgccaattct ttcttagaat tttcgatttg ttggtctgta acgttttcgt
    10321 tgatgtaaag gatccagttg ttaccagtgt tccatccacc catgtgagtg tttcctttgt
    10381 agccatcaag aacgcgaaca cggttttctt taccttcaat tttttcccag ttcttgcctt
    10441 ctggaccgta aacaagaccg ttcaagagtt ctgggttcgt attcaagagg ttcaagattt
    10501 ccattgattt ttctttgttc ttagagttgt ttgagatgac aaagttagca acttgtgttg
    10561 tttggttttt cttgatgaag ttagtaattg gtttgatttg gatatctttg ttggcaacac
    10621 gtgaaagcaa gctgttaccg tagtcagctg gtcctactgt ttcttcacga acgaaccaag
    10681 tatcttgttg aaggtcaaag gaagtatcgc ttgttgcgac gtcttttgga atgtagccag
    10741 cttcatagaa tttgtgaaga gtcttcaagt gttctttgaa acgaggcact tcgtaacggt
    10801 ttacaacttt agtagtatcg ccttcaaggt cgataacgaa tggaagaccg tttgctactg
    10861 ggtagtcaaa attatcagat gggatgaaaa ctttaccaat agcaaatggt actacgtctg
    10921 gagctttttc tttgatttgt ttcaagactg gctcaagagt ttcgtaagaa gtaacacctg
    10981 aaatatcgat accatattta gcaaggagag ttccgttgaa ggcaaagttt tgagatgatg
    11041 caacgttggc tgcaactgga acagcgtaaa tcttaccatt tacagtatta cccttgatgt
    11101 aagctgggtc aagtgctttg taaaggtctt taccttcttt tttgtacaat tctgtcaagt
    11161 cagcgtaagc acctttttga gcatttacaa tatagttatc tgcaaaggca atatcatagt
    11221 tttcaccaga tgatgtgata actgacattt tcttaccata gtcaccccag ccaaggtatt
    11281 ggatatccaa tttggcacca actttttctt caatgatttt gttggcattt gctaacaatt
    11341 catccaagtt gtctggtttg tcaccgattt ggtacatttt gataacaggt ttgtcacctg
    11401 aatcagcagc ttttttgctg ttacctgtca aatttccaca agcagcaaga cctgcagcca
    11461 gagcgactac actagcagat gcaaaagcat attttttcca gtttttcatg ataaaaactc
    11521 ctttttttat ttttaaactt ataaacaatg taatgatctt atactcaata aaaatcaaag
    11581 agcaaactag aaaactagcc gcaggctgct caaagcactg ctttgaggtt gtagataaga
    11641 ctgacgaagt cagttacata tatctacggc aaggcgacgt tgacgcggtt tgaatttgat
    11701 tttcgaagag tattaacttc acacaaggga agttgggaac tgagaaatgt tatttctcaa
    11761 taagcactat tctttcacac caccgatagt caaacctttt acaaagtagc gttggaaaaa
    11821 tggatacaaa atcgcgattg gaagggttgc aaccacaacc atggccatac gacctgtttc
    11881 tttcggtaga gcaactccca gttgaccaat caagccgacc gctttggcaa tgtagtccat
    11941 attttgttgg atttgcatga gcaaatattg caatggatac aagttgtcac tcttgatgta
    12001 aagaagggcg ttgaaccagt cattccagaa accaagagct gttaagagcg tgatggttgc
    12061 gatacctggt agtgacaatg gcaaacagat ttggaagaaa atccgggcct cactggcacc
    12121 atcgatacga gccgattcta gaatggcttc tggaatggtc ttcttgaaga aggaacgcat
    12181 caagatgatg ttaaatggtg agagaagcat tggaacaatc aaggcccaaa cagtgtcacc
    12241 aagctgaagt acacgggtca ccatgatata acctggtacc aaaccagcgt tgaacaacat
    12301 actgagaagg acgaagatgg taaagaatct gcgatactta aaggttgtcc gtgaaatagc
    12361 gtaggcatag gttgttgtga taaagacatt tgtcaatgtc ccaactacgg ttacaaagac
    12421 agagatgaag agggcttgta ggattttatc cttaaactgt gccaaaaact caaaaccgtc
    12481 taagccaaat tgggatggga agaagctata gccgtattgg aggaggcttt tctcgtctgt
    12541 cactgaaata atgataacga atacaaaagg taggatacaa gagagggcaa tcaaacccga
    12601 aatgatactg aagaagatat ctgctttctt actgaaggag tgaatgccga cattatcaat
    12661 tttttctttt ttaattttct tttttgccat attctcctcc tttctagaac aaagctgagt
    12721 ttggatcgac tcgtcttgca agcaagtttg ataggataac cagaatcaaa ccaacaacgg
    12781 attggtaaag accggctgct gcagccatac cgatatctgc tgtctgagtc aaaccattaa
    12841 agacatatac gtccaaaacg ttggttacat tgtaaagctg accagcattg tgtgggattt
    12901 gatagaagag accgaagtct gcgcggaaga tatttccgac tgcaaggatg gtcaatacag
    12961 ttacaagcgg agtcaactga ggaatggtta cgttgcgaat acgttgccac ttgctagctc
    13021 cgtccactgt cgctgcttcg tagtaggttg gatcaattcc catgatcgtc gcatagtaca
    13081 tgacactgct atatccaaag cctttccaaa tacctaggaa aagtaggaga tagggccaga
    13141 tgcccaggtc agcgtagaaa ttgacttctt tgagaccaag actttccaat agatgattga
    13201 acaccccttt atcaatattt aggaaggcat ctgtaaagaa actgatgata acccaagaca
    13261 agaagtaagg gaacaacata gaagtttgaa aaatcttcac cattctctta gaacggagct
    13321 cgctgaggat aatggcaatc cctacagata caactaaacc tagaaagata aagccaagat
    13381 tgtagaggac agtatttcgt gtgataataa aggcgtctct tgaactaaat aagaatctaa
    13441 aattatcgag tccgacccat ttactattta tgatactatc tatgaaacca ttactggtca
    13501 tgtggtagtc tttgaaggca accacgttcc caaatactgg aatgtaaaag aatagaatca
    13561 accagagtgc ccctggcaaa accatcaaga gaaagatcca gttgtctctc aatgtttttg
    13621 aaaacttttt cataatttcc tcccttttta ttttgatatc catctaaaaa ttctttttta
    13681 gacttttgat aacgattaca ttattagtat actcctattt gcaggttagg ttaaactcct
    13741 aattatagaa aaaactccac aaattatgta gcagatttaa aactttatca ccactatcaa
    13801 acaaatgtcc taaatcaatt gtttatttta tctctattag cccagtgatg gcgtcactct
    13861 gttataagca tccaacaacg gggtatactg aaaaatctcc agactaggga actcagcgat
    13921 agttcctaat ctggagattt ttaatatgtt attaggcgtt tgctttcaac ttagcaataa
    13981 cctctttaag attatcaatc aactctgctg cagtatgctc agagcctttt tcatctgcca
    14041 agaacaaaac tgctttttga agttcttttt gagagttttc aaggacatcc ttatctactg
    14101 tttcaaggtt tgagtcttta agaagtttac ttaattcctt ggctaatttc ttgagtttga
    14161 tttgcagact catcttctcc tgctgtttct ttgcccgctg tttgtcctcc atccttagtt
    14221 gctgactggc tttccttaat ggactctagg gaagcaatgg catctttgac tgtttgcaag
    14281 atatcacgta aaccttgctc tgtcaaacta tcatctgcaa aagctttatt agcctctgcc
    14341 aaaaccagac gtgctgaatc tgtggtagga ttcgatacac ctgtcaatga tctcaaaaga
    14401 ttttctaagg tttgagtctg cttactaata ctagactaaa atcaaaaagt attatataac
    14461 agtgatatga aatcaactaa agaagaaatc caaaccatca aaacactttt aaaagactct
    14521 cgtacagcta aatatcataa acgccttcaa atcgttctat tttgtctgat gggcaaatct
    14581 tataaagaga ttatagaact tttatagtag tttgaaataa gatgtgaaca tctctatcag
    14641 gaaagtcaaa ttaatttata gaaatatttt agcagccaag gtgtactgtt atagattcaa
    14701 tacactatac ttggtggttt agctctcctg ttttctcttt tagctttaac cagccataaa
    14761 tggtattacg tgagatttgg aaaacgtgtg atgcttctgt tatactacct gttcgctcac
    14821 aataagagag aactttttta cgaaaatcta ttgaatatgc cataaaagga ttataccaca
    14881 ttgtgtacta tttttggttc attttactat atcactttgg actatatcgg tctagttatg
    14941 tctcaacgat tatagctgga tactaagaga aatcaaaaaa gcactaaggg agaacgtccc
    15001 aaagtgctta atatcaaggc ctatcttatt caataaaata ttacaacatt ttgttgtaga
    15061 attcaacgac aagtgcttcg ttgatttctg ggttgatttc gtcgcgttct ggcaagcgag
    15121 tcaatgaacc ttccaatttt tcagcgtcga atgatacgaa tgctggacgt ccaagagtag
    15181 cttctactgc ttcaaggatt gctggaactt tcaatgattt ttcacgaact gagatcactt
    15241 gacctggagt tacgcggtat gatgggatat caacgcgttt cccgtcaaca aggatgtgac
    15301 cgtggtttac gaattgacga gcttgacgac gagtagtcgc gagaccaaga cggtaaacaa
    15361 cgttatccaa acgacgttcc aaaagaagca taaagttgaa acctaggatt ccgcctttga
    15421 tttttgtagc ttgtacgaac aagttacgga attgtttttc acctacaccg taagtgaaac
    15481 gaagtttttg tttttcagcc aattgcaaac cgtattctga caatttagaa cggttgtttg
    15541 gtccgtgttg tcctggtacg tagttacgac gtgccaattc tttacctgta cctgtaagtg
    15601 aaaggccaag gcgacgagct tgtttccaag atggtcctgt ataacgtgac atatgaatgt
    15661 cctcctgata taaataatat ttcggtggaa atagtcactt agaaagccct gattcgtgca
    15721 gatgcccttc gcctaaacag ccaaggttac ttgtcataag acacctgttg acgagcttca
    15781 tgctttcctg ctgatatttc acacaaaatc tattctacca tgaatagctg gatttgtaaa
    15841 ggggttttag gctttatttt cactaccaga gaggttgaga acgagggtaa aggtacttcc
    15901 tagaccgtac tggctgctga ctgtgatttc cccacccaat tgatgggcca attcacgcgc
    15961 aatcgcaagt cctaatccat gaccacctgt cttcatgtta cgcgaagttt cgacacgata
    16021 aaggcgtttg aaaatatttt ccaaatcctc tggggcaata ccctgccctt catcggtcac
    16081 actgattgaa agctggtcct tctccagctt agccaccact tccagcttgg ttcctggagc
    16141 agaatattta aaagcgttat cgaccagatt caccaagata cgagaaagct tagcataatc
    16201 tccctcaatc cgggcagact ctgggattac ctgcaagtgg acatctcttc tctcctgctc
    16261 aatcaaaaac tgaaattcac tcatgcactc aattaagagc ttgtccagaa aaatactgtc
    16321 tttactggta gtttccacct gatttctagc tgtgtttagg gtcaaaaaat tcaactcctc
    16381 aaccagttta ttgagcctct ccgtctggcg tccaatggtt gctagataat gagcttgctc
    16441 cgactccttg ataatcccat ccaaaatccc ttctaccgtc gcttggatcg aagtgatagg
    16501 agtcttaata tcatgcgaca actgggcaat catcaagccc ttttctcgtt cgctttcttc
    16561 caaggaatca aagcttacct gcaaatcatg ggacatctca ttaaaagttt gccctaattg
    16621 ctgaaattct acaggacctt gaacctccaa atttgaagga aaatccttgg ccgctacccg
    16681 cttggcatgc tccttgagtt tgcccaacga cgtaaagact ggcaatagga gaaagagact
    16741 aatcccagca ccgacaaggc tggcaacgat ggtcatccca agcaaaaagt aaatctcgcc
    16801 tttcgcaatc agcatttttt gaacagccca aaaaacaacc aaaatggtta agagggttga
    16861 aataatatat ccaaccaaaa tataactttt tagtttcatg tttgtcctct cggtttctct
    16921 atcttatatc ccaaccccca aactgtctta atagtgggag tttggtcact actatatttt
    16981 gccagctcct gtcgaagagc atggatatgc acattcaagg tattggtgtc atccacgtag
    17041 tcttctttcc agatcttttc atagaggtct gtcttggaga aaactcgctc tggattacta
    17101 gctaaaatcc acagcaattc aaatgattta acagttaaat ccagcatttc ttctcctatt
    17161 tgaacttcat gactactatg attcattttt agattgccaa gggaaatcag ctctgtttcg
    17221 cccccacgat gaaggcggcg caaaatattg tggacacgca aaaccagctc acgtgggcta
    17281 aaaggcttag caataaaatc atctgctccc aagctcaggc cgtaaatctt gtcctgttca
    17341 ctggtcttag cagtaataaa taggaaaggc tgctctggtg ataagtattg aacctcactg
    17401 attaaatcat aaccatccat ccgaggcatc atgacatctg tgataatcaa atcaatcggt
    17461 tttttcttga acagctctag cgcttccagt ccatcatggg ctaccaagac ctgataacct
    17521 gcctgaatta agtatctctg atgaatatct gtgatttcta cctcgtcgtc aacgagtaaa
    17581 attgtctttc ccatctgtct ctcctttgat aaaaacagtg ctatactgct ttaagtataa
    17641 cactattttt attgttttac gatgatttta atctgctatt gaaagaaagt cctgattgct
    17701 gattgagttg ttaaactaat cttagtcagc ccactatcca tcatttattt ccttagctga
    17761 ttagttttct tcttttttgt ttttcaaacc tagaccaccg agtaaacctg caagcgcaag
    17821 cccaaggaaa ccaatacttg ccattgatgt ttgagtctca ccagtatttg gtagcatagc
    17881 tttatcctct gacatcatcg tatcagacat cttgttagca gaagcagcca tgttttcacc
    17941 tgccatcgtg ttggtagaac ttgtcatggt gtcagcaggc atgctatctg tagtacctgt
    18001 agcatgattg tgattcatcg gagtcacgcc agaaccagag ttagaaggtg ataatgaacc
    18061 atttgctgtg tctgatgttt ctttaacatt tat
//
LOCUS       DAVFER010000043        18027 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1105170250
            SAMEA2167659-rid19724873.denovo.043, whole genome shotgun sequence.
ACCESSION   DAVFER010000043 DAVFER010000000
VERSION     DAVFER010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2167659
            Sequence Read Archive: ERR388902
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18027)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18027)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928716.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928716.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 04:07:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,118
            CDSs (total)                      :: 2,073
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 120
            CDSs (without protein)            :: 120
            Pseudo Genes (ambiguous residues) :: 0 of 120
            Pseudo Genes (frameshifted)       :: 67 of 120
            Pseudo Genes (incomplete)         :: 47 of 120
            Pseudo Genes (internal stop)      :: 34 of 120
            Pseudo Genes (multiple problems)  :: 23 of 120
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18027
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2167659-rid19724873.denovo.043"
                     /strain="1105170250"
                     /db_xref="taxon:1313"
     gene            224..1669
                     /gene="cps4A"
                     /locus_tag="VU534_001624"
     CDS             224..1669
                     /gene="cps4A"
                     /locus_tag="VU534_001624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000091082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     Cps4A"
                     /protein_id="HEU1514182.1"
                     /translation="MSRRFKKSRSQKVKRSVNIVLLTIYLLLVCFLLFLIFKYNILAF
                     RYLNLVVTALVLLVALVGLLLIIYKKAEKFTIFLLVFSILVSSVSLFAVQQFVGLTNR
                     LNATSNYSEYSISVAVLADSEIENVTQLTSVTAPTGTNNENIQKLLADIKSSQNTDLT
                     VNQSSSYLAAYKSLIAGETKAIVLNSVFENIIESEYPDYASKIKKIYTKGFTKKVEAP
                     KTSKSQSFNIYVSGIDTYGPISSVSRSDVNILMTVNRDTKKILLTTTPRDAYVPIADG
                     GNNQKDKLTHAGIYGVDSSIHTLENLYGVDINYYVRLNFTSFLKLIDLLGGIDVYNDQ
                     EFTAHTNGKYYPAGNVHLDSEQALGFVRERYSLADGDRDRGRHQQKVIVAILQKLTST
                     EVLKNYSTIINSLQDSIQTNMPLETMINLVNAQLESGGNYKVNSQDLKGTGRMDLPSY
                     AMPDSNLYVMEIDDSSLAVVKAAIQDVMEGR"
     gene            1671..2402
                     /gene="cps4B"
                     /locus_tag="VU534_001625"
     CDS             1671..2402
                     /gene="cps4B"
                     /locus_tag="VU534_001625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     Cps4B"
                     /protein_id="HEU1514183.1"
                     /translation="MIDIHSHIVFDVDDGPKSREESKALLAESYRQGVRTIVSTSHRR
                     KGMFETPEEKIAENFLQVREIAKEVASDLVIAYGAEIYYTPDVLDKLEKKRIPTLNDS
                     RYALIEFSMNTPYRDIHSALSKILMLGITPVIAHIERYDALENNEKRVRELIDMGCYT
                     QVNSSHVLKPKLFGERYKFMKKRAQYFLEQDLVHVIASDMHNLDGRPPHMAEAYDLVT
                     QKYGEAKAQELFIDNPRKIVMDQLI"
     gene            2411..3103
                     /gene="cpsC"
                     /locus_tag="VU534_001626"
     CDS             2411..3103
                     /gene="cpsC"
                     /locus_tag="VU534_001626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000664160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     CpsC"
                     /protein_id="HEU1514184.1"
                     /translation="MKEQNTIEIDVFQLVKSLWKRKLMILIVALVTGAGAFAYSTFIV
                     KPEYTSTTRIYVVNRNQGDKPGLTNQDLQAGTYLVKDYREIILSQDVLEEVVSDLKLD
                     LTPKGLANKIKVTVPVDTRIVSISVNDRVPEEASRIANSLREVAAQKIISITRVSDVT
                     TLEEARPAISPSSPNIKRNTLIGFLAGVIGTSVIVLHLELLDTRVKRPEDIENTLQMT
                     LLGVVPNLGKLK"
     gene            3113..3796
                     /gene="cps4D"
                     /locus_tag="VU534_001627"
     CDS             3113..3796
                     /gene="cps4D"
                     /locus_tag="VU534_001627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     Cps4D"
                     /protein_id="HEU1514185.1"
                     /translation="MPTLEIAQKKLEFIKKAEEYYNALCTNIQLSGDKLKVISVTSVN
                     PGEGKTTTSINIAWSFARAGYKTLLIDGDTRNSVMLGVFKSREKITGLTEFLSGTADL
                     SHGLCDTNIENLFVVQSGSVSPNPTALLQSKNFNDMIETLRKYFDYIIIDTPPIGIVI
                     DAAIITQKCDASILVTATGEANKRDIQKAKQQLKQTGKLFLGVVLNKLDISVNKYGVY
                     GSYGNYGKK"
     gene            4137..4772
                     /gene="cps4E"
                     /locus_tag="VU534_001628"
     CDS             4137..4772
                     /gene="cps4E"
                     /locus_tag="VU534_001628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010963212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     Cps4E"
                     /protein_id="HEU1514186.1"
                     /translation="MKNGNRIYSWRLFMYGIIKRLGDILLSLIGIIILCPVFMIIAIA
                     IKLDSEGPVIFKQKRFGIHKEYFYILKFRSMKIDAPKNVAPRNLYNPEQWITKVGAFL
                     RKTSLDELPQLFNILVGNMSIVGPRPAGINELDLIAERDKYGANDILPGLTGWAQING
                     RDTLSVEMKTELDGYYVKHLSLIMDIRCIVKTIPYVLKRKGIVEGSGKKES"
     gene            4781..6010
                     /gene="cps4F"
                     /locus_tag="VU534_001629"
     CDS             4781..6010
                     /gene="cps4F"
                     /locus_tag="VU534_001629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     Cps4F"
                     /protein_id="HEU1514187.1"
                     /translation="MKILFVCQHYKPEPFRLSDICEDLVRKGHEVSVLAGIPNYPEGK
                     IYADYRHNKKRREIIEGVTIYRSYTIPRKKSVVFRLLNYFSFAISSTLGVLLGRYKTK
                     DGSNFDCVFVNQLSPVMMAWAGMAYKKKYKKPMFLYCMDVWPDSLTVGGVKQDGLIFK
                     LFKFISKKVYRASDYIFVTSPSFKNYFVKQFDISEQKITYLPQYAEDLFIPDESIVNK
                     ESVDLTFAGNIGKAQNLETILKAASLIEKNTNLPKKIHFHFVGDGTELLSMKALAHEL
                     ELKNISFYGRRSLEEMPSFYKKSDAMLVSLIGDSIVSRTIPGKVQSYMAAGKPIIGAI
                     SGDAKIIVEEANCGYVSPERDVKQLAKNICKFSMLSIKRQRELGKKARCYYENHFSKE
                     QFMLELETCLERESKKE"
     gene            6015..7091
                     /gene="cps4G"
                     /locus_tag="VU534_001630"
     CDS             6015..7091
                     /gene="cps4G"
                     /locus_tag="VU534_001630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001264338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     Cps4G"
                     /protein_id="HEU1514188.1"
                     /translation="MRVLFILSDNIYLTPYFNFYKELLKKLSISYDVIYWDKNINEII
                     TKQNYYRISFSGKGKLSKILGYVKFRKEIKKKLKENDYDMILPLHSIVSFILVDFLLF
                     SFKNRYIYDIRDYSYEKFLVYRLVQKQLVKNSLMNIVSSDGYKFFLPMGEYFTTHNLP
                     NMIELNEVKQLKNNSTFPIQLSYIGLIRFQEQNKKIIDFFANDSRFQLNFIGTNAGEL
                     REFCQEKNISNVNLVDTFQPKDTMSFYKNTDVVLNLYGNHTPLLDYALSNKLYFAALL
                     YKPILVCEDTYMEKVSIENGFGFVLPMKDESEKDCLALYIQNLDRKQLIKNCDNFMDR
                     ISLEKQKTEIELEKRILSLRKKND"
     gene            7084..8202
                     /gene="cps4H"
                     /locus_tag="VU534_001631"
     CDS             7084..8202
                     /gene="cps4H"
                     /locus_tag="VU534_001631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000598627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     Cps4H"
                     /protein_id="HEU1514189.1"
                     /translation="MIKVLHLFTTLDSGGVESFLFNYYSHIDRKKIQFDFIVPGKEQG
                     FLEDKMKELGAKVYHVPLLRKKPLHQFLSLARIIKKGDYDIVHCHGYKSAIGLILSKI
                     IGCKIRIIHSHMAYVTENSFQKVLRKLVTILVKILATHWFACGEDSAKWLYGEKAYKD
                     GKIEIIFNAIDLKKYQFLSDVREKCRRELDVSNKFVLGNIARLSDQKNQSYLFNVLKE
                     LILIKPNVILLLVGNGEDEQKLKQKALELNLTPYVLFLGRRTDISDLLSAMDVFLLPS
                     KYEGLPVSLVEAQASGLQILSSDTVTQEVDVTKNISYLPINEESVLLWKDKVLSLTSE
                     ECNRFEINNSMTDGLYDICYQASKLLNRYQEMCVIKEI"
     gene            8203..9603
                     /gene="wzy"
                     /locus_tag="VU534_001632"
     CDS             8203..9603
                     /gene="wzy"
                     /locus_tag="VU534_001632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001193768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen polysaccharide polymerase Wzy"
                     /protein_id="HEU1514190.1"
                     /translation="MQTKYICRVTLVTLSFIFAFCYLFWTLDNWNNGFLISNYVPSIF
                     IWVCFLIIFQITGFILQKVSIYDFSVWYLILSYFFMFGLIFNEYMGFQTTLLWSPSNF
                     YNNEELFHSYIFIIWILFCYSVGYLFFYSDGKVHYHSEVQNYQENEEKILYNAGRILT
                     GVGFISRVITDSKTVLAVRAANSYSAYSEAASSGIIDDLGVLMLPGVFSLFYSDKLSR
                     VIKRTIFWVMLFYLILIMILTGSRKIQVFSILALVLVYTQSLGITFSKKRVLVFLIVT
                     VFLLNVLVVIRGHRFDLNTIGIYLFDSFSSLDFVKNILGEVFSESGLTSLTVASAVTV
                     VPSSIPYEYGMTFLRTILSIFPIGWLVGDFFDKASATVVINKFLGLPVGSSFVEELFW
                     NFGYYGGVFWSFVLGIFSGWRLNFRAFQTSKISKVIYFSVISQLLLLVRSSSIDVYRP
                     IMYSLIMIFIFRRLKK"
     gene            9618..10685
                     /locus_tag="VU534_001633"
     CDS             9618..10685
                     /locus_tag="VU534_001633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000902274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide pyruvyl transferase family
                     protein"
                     /protein_id="HEU1514191.1"
                     /translation="MLHGATDYGSSNYGDYLYGEIVYDLLESKGYEVSFYNPSDFFQM
                     YLKEYRQKQSFTKKQADAILYIPGGYFGEGHNARFRDNLIQFKRFLPLGIWASYFKKP
                     IGVLGIGAGPNNDSLMNYGIKRIINHAQFITVRDRESFDSLKHLSPSAPVHETFDLII
                     SSKLREEKTEQLCQLKREAKDKKIILVHYNHSKKALEKFAESISLFLENNPNYYVVVT
                     SDSILPYEDAYYQEFRKLVRTEDCFQFKYHSPAEMTSLLKMVDVVLTCKLHVGVVATC
                     FNKSVIAIACHPEKTARYYGAIGELQRCESLFDSSVNSIVKKLETFHLKPITIPSELV
                     LKARSSLDYLDLFLEGLVRES"
     gene            10675..11916
                     /locus_tag="VU534_001634"
     CDS             10675..11916
                     /locus_tag="VU534_001634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000861791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HEU1514192.1"
                     /translation="MKVDRISFIKNTSSLYILNIVKLLFPLLTLPYLTRVLSLDAYGM
                     VIYVKALIAYVQLVIDFGFMISATKNIVNACTTPSKIGRIVGDTLVEKIFLSIISILI
                     YTILMWQIPIMRENILFSVFYLLATVTNIFIFDFLFRGIEKMHAVAIPYIISKTIITI
                     LTFIVVKDDSSILWIPILEGIGNLVAAVVSYRFLHYYGIKLSFSYLSVWVKDLKESSI
                     YFLSNFATTIFGVFTTVISGFYLQSQEIAFWGIAMQLLSAAKSLYNPIANSLYPHMIR
                     TKDIQSVKSINRIMFIPIIFGVLIVLFFSNQILSIIGGEKYTVSADFLKYLLPAFVAS
                     FYSMIYGWPVLGAIDKVKETTMTTILASIVQTLGLGIFILSDNFSLVTLAICSSMSEV
                     VLWISRYLIYFKNRSLFVRSK"
     gene            11921..13018
                     /gene="cps4I"
                     /locus_tag="VU534_001635"
     CDS             11921..13018
                     /gene="cps4I"
                     /locus_tag="VU534_001635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000758382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     Cps4I"
                     /protein_id="HEU1514193.1"
                     /translation="MKKVVVVFGTRPEAIKMCPLVKELRTRKNIETLVCVTGQHRQML
                     DQVLDTFGIIPDFDLSIMKDKQTLFDVTIGILEGMKAILESEKPDLVLVHGDTSTTFA
                     SSLAAFYLQIPIGHVEAGLRTYDIYSPYPEEFNRQAVGVLAQYHFTPTQLSKDNLLRE
                     GKTPESIFVTGNTAIDALQTTIQEDYTHPELEWIGESRFILITAHRRENLGEPMRHMF
                     RAIRRIIEEYSDVKAIYPIHMNPRVRQIAEEELSGCERIKMIEPLEVLDFHNFLSRSY
                     LILTDSGGIQEEAPSLGKPVLVMRDTTERPEGIEAGTLKLVGADENNIYRHFKELLEN
                     DSVYQAMSQASNPYGDGTACKKIADILEGEV"
     gene            13022..14077
                     /gene="cps4J"
                     /locus_tag="VU534_001636"
     CDS             13022..14077
                     /gene="cps4J"
                     /locus_tag="VU534_001636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000077424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     Cps4J"
                     /protein_id="HEU1514194.1"
                     /translation="MSQFTGKTLLITGGTGSFGNAVLKRFLETDVSEIRIFSRDEKKQ
                     DDMRHEFQVKVPEVAGKIRFYLGDVRDLASVKNAMHGVDYVFHAAALKQVPSCEFFPV
                     EAVKTNILGTENVLTAAIEAGVKQVICLSTDKAAYPVNAMGTSKAMMEKIAVAKSRTV
                     NPEHTKICVTRYGNVLCSRGSVVPLWIEQIKQGNALTITEPSMTRFVMTLEEAVDLVL
                     FAFEEGKSGDILVQKAPACTIEVLAKAVSEIFASEQDIKIIGIRHGEKRYETLLTNEE
                     CANAIDLGDFYRVPSDNRNLNYDKYFKDGSTNRNLLTEFNSNNTDLMDVEQVKRKLLE
                     LDEIQTAIRDMVADEEM"
     gene            14177..15406
                     /gene="cps4K"
                     /locus_tag="VU534_001637"
     CDS             14177..15406
                     /gene="cps4K"
                     /locus_tag="VU534_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000594468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     Cps4K"
                     /protein_id="HEU1514195.1"
                     /translation="MIKNILITGAKGFVGKNLICTLEALKDGRDRTRPNLEIGEIFQY
                     DRDTDPILLDEYCKKADFVFHLAGVNRPQNPDEFMEGNYGFSSRLLEILEKYENTCPV
                     LLSSSTQASLEGRFSNSIYGQSKLAGEELFFEYGKKTGAPVLVYRFPNLYGKWCRPNY
                     NSAVATFCYNLAHDLPIQVNDPSVELELLYIDDLIQECLTALEGNPHRCNLDGLQILP
                     SPSGNYCYVPTTHRATLGEIVSLLETFKKQPDSLVMPEIPQGSFKKKLYSTYLSYLPV
                     DKFKFPLKMNIDERGSFTELLKTENTGQFSVNISKPGITKGQHWHHSKWEFFMVVSGR
                     ALIQERRIGLDENGQEYPILNFEVSGDKIEAIHMIPGYAHNIINLSDTENLITVMWAN
                     ESFDPRHPDTFFEQVEK"
     gene            15407..16591
                     /gene="cps4L"
                     /locus_tag="VU534_001638"
     CDS             15407..16591
                     /gene="cps4L"
                     /locus_tag="VU534_001638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000695335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     Cps4L"
                     /protein_id="HEU1514196.1"
                     /translation="MKIKTDYSDIHFKDNGKLKLLIIVGTRPEIIRLSSVITKCRKYF
                     DVILAHTGQNYDYNLNGIFFDNLGLDTPDVYMDAVGDDLGATVGNIINTSYKLMNQIK
                     PDALLILGDTNSCLSAIAAKRLHIPIFHMEAGNRCKDECLPEETNRRIVDVISDVNLA
                     YSEHARKYLHECGLPKERTYVTGSPMAEVLHKNLSAIESSDIHERLGLKKGGYILLSA
                     HREENIDTDKNFISLFTAINQLAEKYNMPILYSCHPRSKKRLQESGFKLDKRVIQHEP
                     LGFHDYNCLQMNAFVVVSDSGTLPEESSFFTSQGYPFPAVCIRTSTERPESLDKAGFI
                     LAGIDENSLLQAVETAVSLAQDEDFGLPVPDYVEENVSTKVVKIIQSYTGIVDKIVWR
                     KS"
     gene            complement(17182..17758)
                     /locus_tag="VU534_001639"
                     /pseudo
     CDS             complement(17182..17758)
                     /locus_tag="VU534_001639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007897432.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus and C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(17834..>18027)
                     /locus_tag="VU534_001640"
     CDS             complement(17834..>18027)
                     /locus_tag="VU534_001640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000523994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU1514197.1"
                     /translation="ADETSYRVLESDSHLTYYWTFLSGKAEKQGITLYHHDQCRSGSV
                     VQEFLGDYSGYVHCDMLRQ"
BASE COUNT         5835 a         2620 c         3593 g         5979 t
ORIGIN      
        1 ttagattgaa actagaatag tacacctctg cttctaaaac attgttagaa atcgatttga
       61 ctgtcctgaa cgatttgttc tgttcttatt tcattttact atatttttgt ttcgcgggaa
      121 gtctactaag atacttaaag atgcagatag taaaaataaa ggtgtagaca ttaccgtaaa
      181 aaagtgatat aatcgtataa tgttcaatgt ataggtatta atcatgagta gacgttttaa
      241 aaaatcacgt tcacagaaag tgaagcgaag tgttaatata gttttgctga ctatttattt
      301 attgttagtt tgttttttat tgttcttaat ctttaagtac aatatccttg cttttagata
      361 tcttaatcta gtggtaactg cgttagtcct actagttgcc ttggtagggc tactcttgat
      421 tatctataaa aaagctgaaa agtttactat ttttctgttg gtgttctcta tccttgtcag
      481 ctctgtgtcg ctctttgcag tacagcagtt tgttggactg accaatcgtt taaatgcgac
      541 ttctaattac tcagaatatt caatcagtgt cgctgtttta gcagatagtg agatcgaaaa
      601 tgttacgcaa ctgacgagtg tgacagcacc gactgggact aataatgaaa atattcagaa
      661 attactagct gatatcaagt caagtcagaa taccgatttg acggtcaacc agagttcgtc
      721 ttacttggca gcttacaaga gtttgattgc aggggagact aaggccattg tcctaaatag
      781 tgtctttgaa aacatcatcg agtcagagta tccagactac gcatcgaaga taaaaaagat
      841 ttatactaag ggattcacta aaaaagtaga agctcctaag acgtctaaga gtcagtcttt
      901 caatatctat gttagtggaa ttgacaccta tggtcctatt agttcggtgt cgcgatcaga
      961 tgtcaacatc ctgatgactg tcaatcgaga taccaagaaa atcctcttga ccacaacgcc
     1021 acgtgatgcc tatgtaccaa tcgcagatgg tggaaataat caaaaagata aattgactca
     1081 tgcgggcatt tatggagttg attcgtccat tcacacctta gaaaatctct atggagtgga
     1141 tatcaattac tatgtgcgat tgaacttcac ttcgtttttg aaattgattg atttgttggg
     1201 tggaattgat gtttataatg atcaagaatt tactgcccat acgaatggaa agtattaccc
     1261 tgcaggcaat gttcatcttg attcagaaca ggctctcggt tttgttcgtg agcgctactc
     1321 cctagcagat ggcgatcgtg accgcgggcg ccatcaacaa aaggtgattg tggctatcct
     1381 tcaaaaatta acgtcaaccg aagtgctgaa aaattatagt acgatcatta atagcttgca
     1441 agattctatc caaacaaata tgccacttga gaccatgata aatttggtca atgctcagtt
     1501 agaaagtgga gggaattata aagtaaattc tcaagattta aaagggacag gtcggatgga
     1561 tcttccttct tatgcaatgc cagacagtaa cctctatgtg atggaaatag atgatagtag
     1621 tttagctgta gttaaagcag ctatacagga tgtgatggag ggtagatgaa atgatagaca
     1681 tccattcgca tatcgttttt gatgtagatg acggtcccaa gtcaagagag gaaagcaagg
     1741 ctctcttggc agaatcctac agacaggggg tgcgaaccat tgtttctacc tctcaccgtc
     1801 gcaagggcat gtttgaaact ccggaagaga agatagcaga aaactttctt caggttcggg
     1861 aaatagctaa ggaagtggcg agtgacttgg tcattgctta cggggctgaa atttattaca
     1921 caccagatgt tctggataag ctggaaaaaa agcggattcc gaccctcaat gatagtcgtt
     1981 atgccttgat agagtttagt atgaacactc cttatcgcga tattcatagc gccttgagca
     2041 agatcttgat gttgggaatt actccagtca ttgcccacat tgagcgctat gatgctcttg
     2101 aaaataatga aaaacgcgtt cgagaactga tcgatatggg ctgttacacg caagtaaata
     2161 gttcacatgt cctcaaaccc aaactttttg gcgaacgtta taaattcatg aaaaaaagag
     2221 ctcagtattt tttagagcag gatttggttc atgtcattgc aagtgatatg cacaatctag
     2281 acggtagacc tcctcatatg gcagaagcat atgaccttgt tacccaaaaa tacggagaag
     2341 cgaaggctca ggaacttttt atagacaatc ctcgaaaaat tgtaatggat caactaattt
     2401 aggagaaatg atgaaagaac aaaatacgat agaaatcgat gtatttcaat tagttaaaag
     2461 cttgtggaaa cgcaagctaa tgattttaat agtggcactt gtgacaggtg cgggggcttt
     2521 tgcatatagc acttttattg ttaagccaga atatacgagt accacgcgaa tttacgtagt
     2581 gaatcgcaat caaggagaca agccggggtt gacaaatcag gatttgcagg caggaactta
     2641 tctggtaaaa gactaccgtg agattatcct ttcgcaggat gttttggagg aagttgtttc
     2701 tgatttgaaa ctagatttga cgccaaaagg tttggctaat aaaattaaag tgacagtacc
     2761 agttgatacc cgtattgtct ctatttcagt taatgatcga gttcctgaag aggcaagccg
     2821 tatcgctaac tctttgagag aagtagctgc tcaaaaaatt atcagtatta ctcgtgtttc
     2881 tgacgtgaca acactggagg aggcaaggcc ggcgatatcc ccgtcttcgc caaatattaa
     2941 acgcaataca ctaattggtt ttttggcagg ggtgattgga actagtgtta tagttcttca
     3001 tcttgaactt ttggatactc gtgtgaaacg tccggaagat atcgaaaata cattgcagat
     3061 gacacttttg ggagttgtgc caaacttggg taagttgaaa taggagagaa ggatgccgac
     3121 attagaaata gcacaaaaaa aactggagtt cattaagaag gcagaagaat attacaatgc
     3181 cttgtgtaca aatatacagt tgagcggaga taaactaaaa gtaatttccg ttacttctgt
     3241 taaccctggg gaaggaaaaa caactacttc cataaatata gcatggtcgt ttgcgcgtgc
     3301 aggctataaa actcttttga tcgatggcga tactcgaaat tcagttatgt taggagtttt
     3361 taaatctcgt gaaaaaatta cagggctaac agaattttta tctgggacag ctgatttatc
     3421 tcacggttta tgtgatacaa atattgaaaa tttatttgta gttcaatcgg gatctgtatc
     3481 accaaaccct acagccttgt tacaaagtaa aaattttaat gatatgattg aaacattgcg
     3541 taaatatttt gattatatca ttattgatac accgcctatt ggaattgtta ttgatgcggc
     3601 aattatcact caaaagtgtg atgcgtccat cttggtaaca gcaacaggtg aggcgaataa
     3661 acgtgatatc caaaaagcga aacaacaatt aaaacaaaca gggaaactgt tcctaggagt
     3721 tgttttaaat aaattggata tctcggttaa taagtatgga gtttacggtt cctatggaaa
     3781 ttatggtaaa aaataaaatg aatatagtat ggaaggggac tacaatataa ctctggcatt
     3841 cttacagagc atacttatca gtttattagc ttatgtactg attgcaattt cagaaaccga
     3901 tatgtcttca aataatattc ggtctatttg gaagaataat tgaactggac cttctaattc
     3961 attattgaga actcatatat tactgaaaca aataaatttt gtttagatgg agaaaagttt
     4021 tatctgacgt agaggataaa agaattatat ttctgaaaat cattgagtga ccaaatatat
     4081 attgagtttc tgtagttgca tgtactgcct gatttaattt gtcaaatgga aatagaatga
     4141 aaaatggaaa tagaatttat agttggaggt tgtttatgta cggtataata aaacgattag
     4201 gtgatatatt attatcttta atagggataa taatattgtg tccggttttt atgataattg
     4261 caattgcgat taaacttgat tcagaaggtc cggttatatt taagcaaaaa cgctttggta
     4321 ttcataaaga atacttctat attttgaaat ttaggtctat gaaaatagat gcacctaaaa
     4381 atgtggcgcc tcgaaactta tataatccag agcaatggat tacaaaagta ggggctttct
     4441 tgcgaaaaac atctttggat gaactaccac aattgtttaa tattcttgtt ggtaatatga
     4501 gtattgtagg tcctagacca gcgggtataa atgaactaga tttgattgca gagagagata
     4561 agtatggagc aaatgatatc ttgccagggt taactggatg ggcacaaatt aacgggcgtg
     4621 atactttgtc tgttgagatg aagacggagt tagatggcta ctatgttaaa catctgtctt
     4681 tgataatgga tattagatgt atagttaaga caatacctta cgtactgaaa cgaaaaggta
     4741 ttgtagaggg tagtggtaag aaagaaagtt aaattggaca atgaaaatac tatttgtttg
     4801 ccaacattat aagccagaac cattcaggtt gtcagatatt tgtgaagatt tagttcgaaa
     4861 agggcatgaa gtctctgttt tggctgggat tcctaattac cctgaaggga agatatatgc
     4921 agattatcgt cataataaaa aaagacgtga gattatagaa ggtgttacga tatatcgttc
     4981 ttatacaatc cctagaaaaa aaagtgttgt atttcgattg ttgaattatt ttagctttgc
     5041 aattagttct actttaggag ttttattggg gaggtataaa acgaaagatg gatcgaattt
     5101 tgactgtgta ttcgttaacc aattgtctcc agttatgatg gcatgggctg gtatggctta
     5161 taaaaaaaaa tataagaaac cgatgtttct atattgtatg gatgtttggc cagatagttt
     5221 aaccgtaggt ggagtgaaac aagatggctt gattttcaag ctgtttaaat ttatctcaaa
     5281 aaaagtttac cgagctagtg attatatatt tgtcactagt ccatcattta aaaattattt
     5341 tgtgaagcaa tttgacatat ccgaacaaaa gattacatat ttgccacaat atgcagaaga
     5401 tctttttatc cctgatgaat ctatagttaa taaagaaagt gttgacctaa cttttgctgg
     5461 taatattggc aaagcacaaa atttggaaac tattttgaaa gctgccagtt tgatagagaa
     5521 gaataccaat ttacccaaga aaattcattt tcattttgtt ggagatggta cggaattgtt
     5581 aagcatgaaa gcattagctc atgaattgga gttaaagaat atttccttct atggaagacg
     5641 ttctttggag gaaatgccat ccttctataa aaaatcagat gctatgttag tttctttaat
     5701 aggagactcg atagtttctc gtactatacc tgggaaggta caatcttata tggcggcagg
     5761 caaaccaatt ataggtgcaa tttcaggaga tgctaaaata attgtagaag aagcaaattg
     5821 tggatatgtt agtcccgaac gagatgtaaa acaattggca aaaaatattt gtaaatttag
     5881 tatgttatct attaagagac aaagagagtt aggaaagaaa gctcgttgtt actatgaaaa
     5941 tcacttttca aaagagcagt ttatgctcga actggagaca tgtttagaga gggaaagtaa
     6001 gaaagaataa tttaatgaga gtactgttta tactatctga taatatatat ctaactcctt
     6061 acttcaattt ttataaagaa ttattgaaga aactgtctat tagttacgat gttatatatt
     6121 gggataagaa tattaacgag attattacaa aacaaaacta ctatcgtatt tctttttctg
     6181 gtaaaggaaa attaagtaag atattaggtt atgtaaaatt cagaaaagaa attaaaaaga
     6241 agctaaaaga aaatgattat gatatgatat tgccgttaca tagtattgtg tctttcattt
     6301 tagtagattt tcttctcttt tcatttaaaa atagatatat ttatgatatt cgtgattaca
     6361 gttatgaaaa atttttggtt tatcgtttgg ttcagaaaca attggtgaaa aattctttaa
     6421 tgaatatcgt ttcttcagac ggctataaat tttttttacc aatgggagag tattttacta
     6481 cccataacct acccaatatg atagaattaa acgaggtaaa gcagttaaaa aataatagta
     6541 cgtttccaat tcaactttcc tacattggtt taattcgttt tcaagaacaa aataaaaaaa
     6601 taatcgattt ttttgcaaat gacagtcgat ttcagttgaa ttttataggt actaatgcag
     6661 gagaattaag ggaattttgt caagaaaaaa atatcagcaa tgttaacttg gtggacacat
     6721 tccagcctaa agataccatg tctttttata agaatacaga tgttgttttg aatttatacg
     6781 ggaatcacac tcccttacta gactatgctt tgtctaataa actctacttt gctgcattgt
     6841 tgtataaacc tattttagtt tgtgaagata cttatatgga aaaagtgtca atagagaatg
     6901 gttttggttt cgttttacct atgaaggatg aatcggaaaa agattgtttg gctttgtata
     6961 ttcaaaacct tgacaggaaa cagctaatta agaattgtga taacttcatg gacagaatta
     7021 gtttagaaaa acaaaaaaca gaaatagaat tagagaagcg aatcttaagc ttaaggaaga
     7081 agaatgatta aagtattaca tctatttaca acactagata gtggtggagt agaaagtttt
     7141 ctattcaact attattctca cattgataga aaaaaaattc aatttgattt tattgtgcct
     7201 ggaaaagaac aaggattttt agaggataaa atgaaagaat tgggtgcaaa ggtttatcat
     7261 gtgcctctat taaggaaaaa gcctctacat cagtttctct ctcttgctag aataataaag
     7321 aaaggagatt atgatatagt tcattgccat ggctataaat ctgcaattgg tctgatctta
     7381 tctaaaataa ttggttgtaa aattagaatt attcatagtc atatggctta tgtaacagaa
     7441 aacagttttc aaaaagtatt gcgtaaatta gtaacaattt tggtaaaaat cttagcaact
     7501 cattggtttg catgtgggga agattcggct aagtggttat atggagagaa agcgtataaa
     7561 gacggaaaaa ttgaaattat ttttaatgca attgatttga aaaagtatca atttttgtca
     7621 gatgttagag aaaaatgtcg tagagaatta gatgtgtcaa ataagttcgt attaggaaat
     7681 atagctcgcc tatcagatca aaaaaaccaa agttatttat ttaacgtttt aaaagaactc
     7741 attttaatca aaccaaatgt tattttactc ctagttggta atggtgagga tgagcagaaa
     7801 ttaaaacaga aagctttaga actaaatctg accccatatg tgctattttt agggagaagg
     7861 actgatattt ctgatttatt atctgcgatg gatgtttttt tgcttccgtc taaatatgag
     7921 gggttgcctg tttctctagt agaggctcag gcatcgggat tacaaatttt atcgtcagat
     7981 acagtgacgc aagaagtaga tgtgaccaaa aacattagtt acttacctat caacgaagag
     8041 tctgtgttgc tatggaaaga taaagtactg tctttaacat ctgaggaatg caatcgtttt
     8101 gaaataaata acagtatgac agatggactc tatgatattt gttatcaagc tagtaaatta
     8161 ttgaatcgtt atcaagaaat gtgtgtaata aaggagatat agatgcagac aaagtatatt
     8221 tgtagagtga cactagtgac attaagtttt atatttgctt tctgttactt gttctggact
     8281 ctcgataatt ggaataatgg ttttcttata tctaattatg ttccgtctat atttatatgg
     8341 gtttgctttc taattatttt tcaaattact ggttttattt tacaaaaagt tagtatatat
     8401 gatttttctg tatggtatct gattttatct tattttttta tgtttggatt aattttcaat
     8461 gagtatatgg ggtttcaaac aactctgctg tggagcccta gtaacttcta taataatgaa
     8521 gaattatttc attcatatat ttttataatt tggattttgt tttgttattc tgtaggctat
     8581 ttattttttt atagtgatgg aaaggtacat tatcattcag aagtacaaaa ttatcaggaa
     8641 aatgaagaga aaattttgta caatgcgggt aggattttaa caggagtggg ctttatttct
     8701 agggtaataa ctgattctaa aacagtacta gcagttagag cggcgaatag ctattcagca
     8761 tattcagagg cagctagttc aggaataata gatgatttag gagtacttat gcttcctggt
     8821 gtgttctcct tgttttattc agataagctg tcccgagtta taaagcgtac tattttttgg
     8881 gtaatgttgt tttacctaat tttgataatg atcctaacag gaagtcgtaa aatccaggtg
     8941 ttttcaatct tggcgttggt tttagtatac acacaatctt tagggattac tttttcgaag
     9001 aaaagagtac ttgtattttt aatagtaact gtatttctat taaatgtatt agttgttatt
     9061 agggggcacc gtttcgactt gaatactata ggtatatact tatttgattc cttttcttca
     9121 ttagattttg taaagaatat actaggggaa gtattttcag agtcgggact gaccagccta
     9181 acagtagctt ctgctgtaac tgttgtgcct agtagcattc catatgaata tgggatgaca
     9241 tttctacgca ctatcctatc aatttttcct attggatggt tagttggtga tttttttgat
     9301 aaagcatcag cgacggttgt tattaataaa tttttggggt tacctgtagg ctcttctttt
     9361 gtggaagaat tattttggaa ctttggttac tatggtggtg ttttttggag ttttgttttg
     9421 ggaatattta gtggatggcg attaaatttc agagcttttc aaacaagtaa aatctcaaaa
     9481 gttatttatt tttcggtaat ttctcaacta ttgcttttag tgagaagtag ttcaatagat
     9541 gtttatcgtc ctattatgta tagtttgatt atgatattta tttttaggag gttgaaaaaa
     9601 tagtggtgaa aaaaattatg ttacatggtg caacggatta tggttcaagt aattacggtg
     9661 attatcttta cggtgagatt gtctatgatt tattagaatc taaaggatat gaagtttctt
     9721 tttataatcc atcagatttc tttcaaatgt acttgaaaga atatcgccaa aaacaaagtt
     9781 ttactaaaaa acaagcagat gctattttgt atatcccggg aggatatttt ggggaagggc
     9841 ataatgcacg ttttcgtgat aatttaatcc aatttaaacg atttttacct ttgggaattt
     9901 gggcttcata ttttaaaaag cctataggag tattaggtat tggtgcaggg cctaataacg
     9961 attctttgat gaattatggt ataaagagaa ttattaatca tgctcaattt attacagttc
    10021 gtgatcgaga atcatttgat tctttgaagc atttgtcgcc ttcggctcca gtgcatgaaa
    10081 cctttgattt aattatttca agtaaattaa gagaagaaaa aacagagcag ctgtgtcaat
    10141 tgaaaagaga agctaaagat aagaagataa ttcttgttca ctataatcat tccaaaaaag
    10201 ctcttgaaaa atttgcggaa tcaattagtc tttttctaga aaacaatcct aactattatg
    10261 ttgtagtaac ttcggattcc attctacctt atgaagatgc ttattatcag gaatttagaa
    10321 aattagttag aactgaggat tgttttcaat tcaagtatca ttctcctgca gaaatgacat
    10381 cattgttgaa aatggtagat gtggttttaa cttgtaaatt acatgttggg gtagtggcaa
    10441 catgttttaa taaatctgtg attgccattg catgccatcc agaaaaaaca gcacgttatt
    10501 atggagcaat tggagagtta caacgttgtg aatctttatt tgattcaagt gttaatagta
    10561 ttgtaaagaa acttgaaact tttcatctaa aaccgataac aataccttca gaattggtgt
    10621 tgaaagcgag aagtagtttg gactatttag atcttttttt ggaaggacta gttcgtgaaa
    10681 gttgatagaa tttcatttat aaaaaataca agttctctct atattctgaa tattgttaaa
    10741 ttactatttc ctttattaac actcccgtat ttgacaaggg tgctttcgct agacgcgtat
    10801 ggaatggtta tttatgttaa agcgttaata gcttatgttc aactggtgat tgattttggt
    10861 ttcatgatat cagctacaaa aaatattgta aatgcttgta ctactccctc aaagattgga
    10921 aggatagttg gagatactct agttgaaaaa atatttttat ctatcatttc gattctaatt
    10981 tacaccatat tgatgtggca aatcccaata atgagagaga atattctttt ttcagttttt
    11041 tatttgttag ctacagtgac caatattttt atctttgact ttttatttcg tggaattgaa
    11101 aagatgcatg cagttgcaat tccttatatt atttctaaaa ctatcattac aattttgaca
    11161 tttattgtag taaaagatga ttcttctatt ttatggattc ctatattgga aggaattggg
    11221 aatttagttg ctgcagtagt ttcttataga ttccttcatt attatggaat taaattatca
    11281 ttttcttatc tgtctgtttg ggttaaagat ttaaaggaat cctctattta ttttttatcc
    11341 aattttgcaa ctactatttt tggcgtcttt acgacagtca tttcgggttt ttatttacaa
    11401 agtcaagaga tagccttttg ggggatagca atgcaactgc tttcagcagc aaaatcattg
    11461 tataatccta tagcgaatag tttatatccg catatgatac gtactaaaga tatacaatcg
    11521 gttaagagta ttaatcggat tatgtttatt cctattatct ttggagtttt gatagtttta
    11581 ttcttttcaa atcaaattct ttctataatt ggtggtgaaa aatataccgt ttcagcagat
    11641 tttcttaagt acttattacc cgcttttgtt gctagttttt attctatgat ttacggatgg
    11701 cctgtcttag gagctattga taaagtgaaa gaaactacaa tgacaactat attagcttcg
    11761 attgtccaaa ctttgggatt aggaatattt atcttgtctg ataattttag tttagtaaca
    11821 ttagctattt gttcaagtat gtctgaggtg gtgttatgga ttagccgtta tctaatttat
    11881 tttaagaacc gttcattatt tgttaggagt aagtaaatat atgaaaaaag tagttgtagt
    11941 atttggaact cgtccagaag ccatcaagat gtgtcctttg gtcaaagagt taagaacacg
    12001 taagaatatt gaaacattag tttgcgttac gggccaacac cgtcaaatgt tggatcaggt
    12061 cttggacaca tttgggatta ttcccgattt tgatttgtct attatgaaag ataaacaaac
    12121 tttatttgat gtgaccattg gcattttgga aggaatgaag gctattttag agtcagaaaa
    12181 acctgatttg gtgttagttc atggggatac aagtacgacc ttcgctagtt cactggcggc
    12241 cttttattta cagattccaa ttggtcatgt tgaagctggt ttgcgcactt acgatatcta
    12301 ttcaccatat cctgaagagt ttaatcgtca agcagttggg gttttggctc agtatcattt
    12361 tacaccaaca caactttcaa aagataatct tttaagagaa ggaaaaactc cagagagcat
    12421 atttgtgaca ggtaatacgg cgattgatgc tttacaaact acaattcaag aggactatac
    12481 gcatcctgag ttagaatgga taggagaaag caggtttatt ctaattacag ctcatcgtcg
    12541 tgaaaatctt ggtgaaccga tgagacatat gtttagagca attagaagga ttattgaaga
    12601 atattcagat gtcaaggcta tttatcctat ccatatgaat cctcgtgttc gccaaattgc
    12661 tgaggaagaa ctaagtggct gtgaacgtat caagatgatc gaacctttag aagtattaga
    12721 ttttcacaat tttttatcaa gaagttattt aattttaaca gatagtggtg gtattcagga
    12781 agaggctcca agtttaggaa aacctgtttt ggttatgaga gatacaactg aacgtccaga
    12841 gggaattgaa gcagggactt tgaaacttgt aggtgctgat gaaaataata tttataggca
    12901 ttttaaagaa ttattagaaa atgattcagt ttatcaagca atgagtcaag cttcaaatcc
    12961 atatggagat ggaacggctt gtaagaaaat tgcagacata ctagaaggag aagtgtaata
    13021 tatgtcacaa tttacaggaa aaactctcct aattacagga gggacaggtt catttgggaa
    13081 tgcggttctc aagcgttttt tagaaacaga tgtctcagag attcgtatat tttcgcgaga
    13141 tgaaaagaaa caagatgata tgcgtcatga gtttcaggta aaagtaccag aagtggctgg
    13201 gaaaatccgt ttttaccttg gagatgtgcg tgacttagct tcggtaaaaa atgctatgca
    13261 tggtgtggat tatgtttttc acgctgctgc tcttaaacaa gtaccttctt gtgaattttt
    13321 ccctgtagaa gcggtaaaaa ctaacatttt gggaacggag aatgtcctca ctgcggctat
    13381 cgaagctggt gtaaagcaag ttatctgtct ttctacagat aaggcggctt atcctgtcaa
    13441 tgctatggga acatccaagg ctatgatgga aaagattgct gttgctaagt ccaggacggt
    13501 aaatcctgag catacaaaga tatgtgtgac tcgctatggg aatgttctgt gtagccgtgg
    13561 atctgtcgtt cctctttgga ttgagcaaat taagcaagga aatgctctta caattactga
    13621 acctagcatg acacgttttg tgatgacatt ggaagaagca gtagacttgg ttttatttgc
    13681 atttgaagaa gggaaatctg gagatatact agttcagaaa gcaccagcat gtacgattga
    13741 agtgttggct aaggctgtat cagaaatttt tgcctcagaa caagatatta agattatagg
    13801 tattagacac ggagaaaaaa ggtatgaaac actattaact aacgaagagt gcgcaaatgc
    13861 aattgatttg ggtgattttt atagagttcc tagtgataat cgtaatctta actatgataa
    13921 gtatttcaaa gatggtagta cgaatagaaa tttgttgaca gaattcaata gtaataatac
    13981 cgatttgatg gatgtagagc aagttaaaag aaagttgcta gaattagatg aaatacagac
    14041 agcaattcgt gatatggtag cagacgaaga gatgtaaaat cttttaagat acattaaaat
    14101 tatcaaggat atataatgta tcatgtattg tcgagagagt taactattaa aacagcatat
    14161 aaaataagga gggggcatga ttaaaaatat tttaatcaca ggagcgaaag gatttgtagg
    14221 aaaaaatctt atctgtactc tggaagcttt gaaagatgga cgagatagga ctcgtcctaa
    14281 tttagagatt ggagagattt ttcagtatga tcgtgataca gatccgattt tattagatga
    14341 atattgtaag aaggccgatt tcgtattcca tttagctggt gtcaatcgtc cacagaatcc
    14401 tgatgaattc atggagggaa attacggttt ttcaagtaga ttattggaga ttttagaaaa
    14461 gtatgaaaac acttgtcctg ttctactctc aagttctact caagctagtt tagaaggccg
    14521 attttcaaac tctatatatg gacaatctaa gctagcaggg gaagaactct tctttgaata
    14581 tggaaagaaa acgggagcac ctgtcttagt ttaccgtttc ccgaatcttt atgggaagtg
    14641 gtgccgtcct aactacaatt ctgctgtagc aactttctgt tataatctag ctcacgattt
    14701 acctattcaa gtaaatgatc caagtgtaga attggagttg ctgtatattg atgatttgat
    14761 acaagagtgt ctaactgcat tggaaggaaa tcctcatcgt tgtaatctag atggattaca
    14821 aatcttacct agcccatcag gaaactactg ctacgtacca acgactcatc gtgcaacctt
    14881 aggagagatt gtctctctat tagaaacatt taaaaaacag cctgatagtt tagttatgcc
    14941 tgaaattcct cagggatcgt ttaaaaagaa attgtattct acctacctat cttatttacc
    15001 agtagataag tttaagtttc ctctaaaaat gaatatagat gaacgaggta gttttacgga
    15061 attattaaaa acagaaaata cgggtcaatt ttctgttaat atttctaaac ctggcattac
    15121 caaagggcaa cattggcatc attctaagtg ggaatttttc atggttgttt ctggtcgtgc
    15181 tttaatacaa gagcgtagga tagggctgga tgaaaacggt caagagtatc ctattctgaa
    15241 ctttgaagtg tcgggcgata agattgaagc aatacatatg ataccgggct atgcacataa
    15301 tattattaat ctttctgata cagaaaatct aattactgtc atgtgggcta atgagtcatt
    15361 tgatcctaga catccagata ctttttttga acaagtggag aaataaatga aaattaagac
    15421 agattatagt gatattcact ttaaagataa tggcaaactt aagttattga ttattgtggg
    15481 aacacgtcca gagattatac gtctaagtag tgttatcact aaatgtcgaa agtattttga
    15541 tgttattttg gcacatactg gacaaaacta tgattacaat ttaaatggta ttttctttga
    15601 taatttaggg ttagacactc cggacgtata catggatgct gttggagatg atcttggtgc
    15661 tactgtaggg aatattatta atacttcata caaattgatg aatcaaatta aaccagatgc
    15721 tttattgatt ttaggggata caaattcttg tttatcagct attgctgcca agcgtttaca
    15781 tattccaatt tttcatatgg aggctggcaa tcgctgtaaa gatgagtgcc taccggaaga
    15841 gactaatcgt cggattgttg atgttatttc agatgttaac ttagcatact ctgaacatgc
    15901 acgtaagtat ttacatgagt gtggtttacc taaagagcgc acatatgtaa ctggttctcc
    15961 tatggcagaa gtgttacata aaaatttatc tgctattgag tcttcagata tccatgaacg
    16021 tttgggattg aaaaaaggag gttatatctt actttcagct caccgtgagg aaaatattga
    16081 tacagataaa aattttattt ctctctttac agcaattaat caattagctg aaaagtataa
    16141 tatgccaatc ttatattctt gccatcctag atcaaagaaa aggctacaag agagcggttt
    16201 taaactagat aaacgtgtga ttcagcatga gccactagga ttccatgact ataattgttt
    16261 acagatgaat gcatttgttg tagtatctga ttcgggaact ttaccggaag aaagtagttt
    16321 ctttactagt caaggttatc cttttcccgc tgtatgtatt cgtacaagta cagaacgtcc
    16381 tgagtcctta gataaggcag gatttatttt ggcaggcatt gatgaaaatt ctcttcttca
    16441 agcagttgaa actgctgtta gcttggcaca agatgaggat tttggattac cggttccgga
    16501 ttatgttgag gaaaatgtct ctactaaagt tgttaagata atacagagct atacagggat
    16561 agtggataaa atagtttgga ggaaaagctg aattgtatat ttttaataaa tcaaaacgag
    16621 atgattaatt cttagtagaa caagagtaaa attgaacgta tttgatggaa atgtcttact
    16681 tgatagtcga gggatagcca ttctatcgga tttttggctt gtttttgcgc ttcatgtttg
    16741 atagaataaa gggctctttg tcaactgtag tgggttgaag aaaagctaag cttgagaaag
    16801 gacaaatttc gtcctttctt ttttgatgtt cagagcgata aaaatccgtt ttttgaagtt
    16861 ttcaaagttt cgaaagtaac cgcccaataa cgaagtctat tgaaaaatct ccagactaga
    16921 gaactcatat atagttccta atctggagat ttcttatttg cacttttctt gtacaacttt
    16981 agtccacggt aaataggcct ctaaaacctc tttgtttacg agagtttcct cgtttggaag
    17041 acattctaga agataggata gatatttctc gctatttata atggattgta ataagatatg
    17101 aacaaatcga ttaggaaagg aaaattgatt tatagaaata ttttagcagt cgatgcgtac
    17161 tgttatagat tcaacgcact ataattgatg acgtttagct gtttccaaca aactcataat
    17221 aatagctctt gctttagctc cttcaaaact ttgagaaaat aaccaccctc gcttttttaa
    17281 aaataaccac cctcgttttt ttaaactgag cttaggctaa aagagtccac tggactcttt
    17341 tactccgtcc cataaccaat gatttaatgg cgcgttcagc tagattattg gaaaggacca
    17401 gatgtccgtc ttttaaaatg gtcttaaagg tttcttcata cttgaggctg tattcaattg
    17461 cccttcctag ttttgaaccc gataaaactg actgacgacg gcaccaagca aagaagtctt
    17521 ccagtagggg ttggagatgt tcttgacgtt tctgtagccg ttcatcagct ggcaaagcct
    17581 cccagtctct ttccaaggaa aataactgat cacaataggc taaaccttta gctcctaagg
    17641 atgatttatc tgcttgcttg gggggcactt caaaaaactt ccttctcaca tgcgcccaac
    17701 atccaacaag tgcagcttct tccagttgac gataagcttc tagctgttcg cagtttacca
    17761 agcttagcgt cgccttactc ctaaaccttg gactgctatc gcataggcag aactagagga
    17821 ctaaagtcct aagttactgc cgcaacatat cacaatgaac atagccagaa taatctccta
    17881 ggaattcttg tactactgaa ccacttcgac actgatcatg gtggtaaagc gtaatccctt
    17941 gtttctctgc tttacctgac aaaaaagtcc aatagtaggt cagatggcta tcactctcta
    18001 gaacccgata ggaggtttca tccgcat
//
LOCUS       DAVFER010000044        17744 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1105170250
            SAMEA2167659-rid19724873.denovo.044, whole genome shotgun sequence.
ACCESSION   DAVFER010000044 DAVFER010000000
VERSION     DAVFER010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2167659
            Sequence Read Archive: ERR388902
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 17744)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17744)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928716.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928716.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 04:07:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,118
            CDSs (total)                      :: 2,073
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 120
            CDSs (without protein)            :: 120
            Pseudo Genes (ambiguous residues) :: 0 of 120
            Pseudo Genes (frameshifted)       :: 67 of 120
            Pseudo Genes (incomplete)         :: 47 of 120
            Pseudo Genes (internal stop)      :: 34 of 120
            Pseudo Genes (multiple problems)  :: 23 of 120
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17744
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2167659-rid19724873.denovo.044"
                     /strain="1105170250"
                     /db_xref="taxon:1313"
     gene            <1..230
                     /locus_tag="VU534_001641"
     CDS             <1..230
                     /locus_tag="VU534_001641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001025716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEU1514198.1"
                     /translation="TDRATLNGILERTDAYATGSGFLDSDSVNGITVIRLKDNLDNRM
                     VYVKREEVELSQAGTLFVEVMQEYFDQKRKS"
     gene            227..688
                     /locus_tag="VU534_001642"
     CDS             227..688
                     /locus_tag="VU534_001642"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HEU1514199.1"
                     /translation="MKKRAIVAVIVLLLIGLDQLVKSYIVQQIPLGEVRSWIPNFVSL
                     TYLQNRGAAFSILQDQQLLFAVITLVVVIGAIWYLHKHMEDSFWMVLGLTLIIAGGLG
                     NFIDRVSQGFVVDMFHLDFINFAIFNVADSYLTVGVIILLIAMLKEEINGN"
     gene            678..1565
                     /locus_tag="VU534_001643"
     CDS             678..1565
                     /locus_tag="VU534_001643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEU1514200.1"
                     /translation="MEIKIETGGLRLDKALSDLSELSRSLANEQIKSGQVLVNGQVKK
                     AKYTVQEGDVVTYHVPEPEVLEYVAEDLPLEIVYQDEDVAVVNKPQGMVVHPSAGHTS
                     GTLVNALMYHIKDLSGINGVLRPGIVHRIDKDTSGLLMIAKNDDAHLALAQELKDKKS
                     LRKYWAIVHGNLPNDRGVIEAPIGRSEKDRKKQAVTAKGKPAVTRFHVLERFGDYSLV
                     ELQLETGRTHQIRVHMAYIGHPVAGDEVYGPRKTLKGHGQFLHAKTLGFTHPRTGKTL
                     EFKADIPEIFKETLERLRK"
     gene            1568..3451
                     /gene="cbpE"
                     /locus_tag="VU534_001644"
                     /gene_synonym="pce"
     CDS             1568..3451
                     /gene="cbpE"
                     /locus_tag="VU534_001644"
                     /gene_synonym="pce"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine esterase CbpE"
                     /protein_id="HEU1514201.1"
                     /translation="MKKKLTSLALVGAFLGLSWYGNVQAQESSGNKIHFINVQEGGSD
                     AIILESNGHFAMVDTGEDYDFPDGSDSRYPWREGIETSYKHVLTDRVFRRLKELGVQK
                     LDFILVTHTHSDHIGNVDELLSTYPVDRVYLKKYSDSRITNSERLWDNLYGYDKVLQT
                     AAEKGVSVIQNITQGDAHFQFGDMDIQLYNYENETDSSGELKKIWDDNSNSLISVVKV
                     NGKKIYLGGDLDNVHGAEDKYGPLIGKVDLMKFNHHHDTNKSNTKDFIKNLSPSLIVQ
                     TSDSLPWKNGVDSEYVNWLKERGIERINAASKDYDATVFDIRKDGFVNISTSYKPIPS
                     FQAGWHKSAYGNWWYQAPDSTGEYAVGWNEIEGEWYYFNQTGILLQNQWKKWNNHWFY
                     LTDSGASAKNWKKIAGIWYYFNKENQMEIGWIQDKEQWYYLDVDGSMKTGWLQYMGQW
                     YYFAPSGEMKMGWVKDKETWYYMDSTGVMKTGEIEVAGQHYYLEDSGAMKQGWHKKAN
                     DWYFYKTDGSRAVGWIKDKDKWYFLKENGQLLVNGKTPEGYTVDSSGAWLVDVSIEKS
                     ATIKTTSHSEIKESKEVVKKDLENKETSQHESVTNFSTSQDLTSSTSQSSETSVNKSE
                     SEQ"
     gene            3531..4661
                     /locus_tag="VU534_001645"
     CDS             3531..4661
                     /locus_tag="VU534_001645"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004240022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HEU1514202.1"
                     /translation="MNNRSETMKYKRIVFKVGTSSLTNEDGSLSRSKVKDITQQLAML
                     HEAGHELILVSSGAIAAGFGALGFKKRPTKIADKQASAAVGQGLLLEEYTTNLLLRQI
                     VSAQILLTQDDFVDKRRYKNAHQALSVLLNRGAIPIINENDSVVIDELKVGDNDTLSA
                     QVAAMVQADLLVFLTDVDGLYTGNPNSDPRAKRLERIETINREIIDMAGGAGSSNGTG
                     GMLTKIKAATIATESGVPVYICSSLKSDSMIEAAEETEDGSYFVAQEKGLRTQKQWLA
                     FYAQSQGSIWVDKGAAEALSQYGKSLLLSGIVEAEGVFSYGDIVTVFDKESGKSLGKG
                     RVQFGASALEDMLRSQKAKGVLIYRDDWISITPEIQLLFTEF"
     gene            4671..5933
                     /locus_tag="VU534_001646"
     CDS             4671..5933
                     /locus_tag="VU534_001646"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HEU1514203.1"
                     /translation="MVSRQEQFEQVQAVKKSINTASEEVKNQALLAMADHLVAATEEI
                     LAANALDMAAAKGKISDVMLDRLYLDADRIEAMARGIREVVALPDPIGEVLETSQLEN
                     GLVITKKRVAMGVIGIIYESRPNVTSDAAALTLKSGNAVVLRSGKDAYQTTHAIVTAL
                     KKGLETTTIHPNVIQLVEDTSRESSYAMMKAKGYLDLLIPRGGAGLINAVVENAIVPV
                     IETGTGIVHVYVDKDADEDKALSIINNAKTSRPSVCNAMEVLLVHENKAASFLPRLEQ
                     VLVAERKEAGLEPIQFRLDSKASQFVSGQAAETQDFDTEFLDYVLAVKVVSSLEEAVA
                     HIESHSTHHSDAIVTENAEAAAYFTDQVDSAAVYVNASTRFTDGGQFGLGCEMGISTQ
                     KLHARGPMGLKELTSYKYVVAGDGQIRE"
     gene            5937..6734
                     /gene="proC"
                     /locus_tag="VU534_001647"
     CDS             5937..6734
                     /gene="proC"
                     /locus_tag="VU534_001647"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HEU1514204.1"
                     /translation="MKIGFIGLGNMGASLAKSVLQTRTSDEILLANRSQAKVDAFIAD
                     FGGQASSNEEMFAEADVIFLGVKPAQFSELLSQYQTILEKRESLLLISMAAGLTLEKL
                     ASLIPSQHRIIRMMPNTPASIGQGVISYALSPNCRAEDSELFYQLLAKAGLLVELGES
                     LIDAATGLAGCGPAFVYLFIEALADAGVQTGLPREIALKMAAQTVVGAGQLVLESQQH
                     PGVLKDQVCSPGGSTIAGVASLEAHAFRGTVMDAVHQAYKRTQELGK"
     gene            6850..7488
                     /locus_tag="VU534_001648"
     CDS             6850..7488
                     /locus_tag="VU534_001648"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HEU1514205.1"
                     /translation="MSKGFLVSLEGPEGAGKTSVLEALLPILEEKGVEVLTTREPGGV
                     LIGEKIREVILDPSHTQMDAKTELLLYIASRRQHLVEKVLPALEAGKLVIMDRFIDSS
                     VAYQGFGRGLDIEAIDWLNQFATDGLKPDLTLYFDIEVEEGLARIAANSDREVNRLDL
                     EGLDLHKKVRQGYLSLLDKEGNRIVKIDASLPLEQVVETTKAVLFDGMGLAK"
     gene            7485..8375
                     /locus_tag="VU534_001649"
     CDS             7485..8375
                     /locus_tag="VU534_001649"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000806705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HEU1514206.1"
                     /translation="MKQDQLKAWQPAQFDRFVRILEQDQLNHAYLFSGFFESLEMAQF
                     LAKSLFCTDKVGVLPCEKCRSCKLIEQGEFPDVTLIKPVNQVIKTERIRELVGQFSQA
                     GIESQQQVFIIEQADKMHPNAANSLLKVIEEPQSEVYIFFLTSDEEKMLPTIRSRTQI
                     FHFKKQEEKLILLLEQMGLVKKKATLLAKFSQSRAEAEKLANQASFWTLVDESERLLT
                     WLVAKKKESYLQVAKLANLADDKEKQDQVLRILEVLCGQDLLQVRVRVILQDLLEARK
                     MWQANVSFQNAMEYLVLKEI"
     gene            8415..8732
                     /gene="yabA"
                     /locus_tag="VU534_001650"
     CDS             8415..8732
                     /gene="yabA"
                     /locus_tag="VU534_001650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication initiation control protein YabA"
                     /protein_id="HEU1514207.1"
                     /translation="MDKKELFDALDDFSQQLLVTLADVEAIKKNLKSLVEENTALRLE
                     NSKLRERLGEVEADAPVKAKHVRESVRRIYRDGFHVCNDFYGQRREQDEECMFCDELL
                     YRE"
     gene            8735..9604
                     /gene="rsmI"
                     /locus_tag="VU534_001651"
     CDS             8735..9604
                     /gene="rsmI"
                     /locus_tag="VU534_001651"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001166894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HEU1514208.1"
                     /translation="MQIQKSFKGQSPYGKLYLVATPIGNLDDMTFRAIQTLKEVDWIA
                     AEDTRNTGLLLKHFDISTKQISFHEHNAKEKIPDLIGFLKAGQSIAQVSDAGLPSISD
                     PGHDLVKAAIEEEIAVVTVPGASAGISALIASGLAPQPHIFYGFLPRKSGQQKQFFGL
                     KKDYPETQIFYESPHRVADTLENMLEVYGDRSVVLVRELTKIYEEYQRGTISELLESI
                     AETPLKGECLLIVEGASQGVEEKDEEDLFVEIQTRIQQGVKKNQAIKEVAKIYQWNKS
                     QLYAAYHDWEEKQ"
     gene            9831..10349
                     /locus_tag="VU534_001652"
     CDS             9831..10349
                     /locus_tag="VU534_001652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013852041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClbS/DfsB family four-helix bundle protein"
                     /protein_id="HEU1514209.1"
                     /translation="MRTYENKEELKAEIEKTFEKYILEFDNIPENLKDKRADEVDRTP
                     AENLAYQVGWTNLVLKWEEDERKGLQVKTPSDKFKWNQLGELYQWFTDTYAHLSLQEL
                     KAKLNENINSISAMIDSLSEEELFEPHMRKWADEATKTATWEVYKFIHVNTVAPFGTF
                     RTKIRKWKKIVL"
     gene            10458..11104
                     /locus_tag="VU534_001653"
                     /pseudo
     CDS             10458..11104
                     /locus_tag="VU534_001653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000345255.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
     gene            complement(11093..11897)
                     /locus_tag="VU534_001654"
     CDS             complement(join(11093..11527,11529..11897))
                     /locus_tag="VU534_001654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
                     /protein_id="HEU1514210.1"
                     /translation="MNDEASKQLTDARFKRLVGVQRTTFEEILAVLKTAYQLKHAKGG
                     RKPKLSLEDLLMATLQYVREYRTYEQIAADFGIHESNLIRRSQWVEVTLVQSGVTISR
                     TPLSSEDTVMIDATEVKINRPKKELANHSGKKKFHAMKAQAIVTSQGRIVSLDIAVNY
                     CRDMKLFKMSRRNIGQAGKILSDSGYQGLMKIYPQVQTPRKSSKLKPLTAEDKACNHA
                     LSKERSKIENIFAKVKTFKMFSTIYRNHRKRFGLRMNLIAGIINHELGF"
     gene            11892..12146
                     /locus_tag="VU534_001655"
     CDS             11892..12146
                     /locus_tag="VU534_001655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001244258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HEU1514211.1"
                     /translation="MHRTTIPYFVSQEVYWKVRNIEAEAIRRNCERGAIFSGKIKYHE
                     DSQFKGDHYVECYAVLDNTVIARDRITVPIDPLCGKDFIE"
     gene            12340..13674
                     /gene="trmFO"
                     /locus_tag="VU534_001656"
     CDS             12340..13674
                     /gene="trmFO"
                     /locus_tag="VU534_001656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000083696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate--tRNA-(uracil(54)-
                     C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO"
                     /protein_id="HEU1514212.1"
                     /translation="MSQSYINVIGAGLAGSEAAYQIAERGIPVKLYEMRGVKSTPQHK
                     TDNFAELVCSNSLRGDALTNAVGLLKEEMRRLGSVILESAEATRVPAGGALAVDRDGF
                     SQMVTEKVANHPLIEVVRDEITELPTDVITVIATGPLTSDALAEKIHALNDGAGFYFY
                     DAAAPIIDVNTIDMSKVYLKSRYDKGEAAYLNAPMTKQEFMDFHEALVNAEEAPLSSF
                     EKEKYFEGCMPIEVMAKRGIKTMLYGPMKPVGLEYPDDYTGPRDGEFKTPYAVVQLRQ
                     DNAAGSLYNIVGFQTHLKWGEQKRVFQMIPGLENAEFVRYGVMHRNSYMDSPNLLEQT
                     YRSKKQPNLFFAGQMTGVEGYVESAASGLVAGINAARLFKEESEAIFPETTAIGSLAH
                     YITHADSKHFQPMNVNFGIIKELEGERIRDKKARYEKIAERALADLEEFLTV"
     gene            13758..14495
                     /locus_tag="VU534_001657"
     CDS             13758..14495
                     /locus_tag="VU534_001657"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000013002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HEU1514213.1"
                     /translation="MANPKYKRILIKLSGEALAGERGVGIDIQTVQTIAKEIQEVHSL
                     GIEIALVIGGGNLWRGEPAAEAGMDRVQADYTGMLGTVMNALVMADSLQQVGVDTRVQ
                     TAIAMQQVAEPYVRGRALRHLEKGRIVIFGAGIGSPYFSTDTTAALRAAEIEADAILM
                     AKNGVDGVYNADPKKDKTAVKFEELTHRDVINKGLRIMDSTASTLSMDNDIDLVVFNM
                     NQPGNIKRVVFGENIGTTVSNNIEEKE"
     gene            14504..15061
                     /gene="frr"
                     /locus_tag="VU534_001658"
     CDS             14504..15061
                     /gene="frr"
                     /locus_tag="VU534_001658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HEU1514214.1"
                     /translation="MANAIIEKAKERMTQSHQSLAREFGGIRAGRANASLLDRVHVEY
                     YGVETPLNQIASITIPEARVLLVTPFDKSSLKDIERALNASDIGITPANDGSVIRLVI
                     PALTEETRRDLAKEVKKVGENAKVAVRNIRRDAMDEAKKREKAKEITEDELKTLEKDI
                     QKVTDDAVKHIDDMTANKEKELLEV"
     gene            15121..15975
                     /gene="cvfB"
                     /locus_tag="VU534_001659"
     CDS             15121..15975
                     /gene="cvfB"
                     /locus_tag="VU534_001659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding virulence regulatory protein CvfB"
                     /protein_id="HEU1514215.1"
                     /translation="MNTNLASFIVGLIIDENDRFYFVQKDGQTYALAKEEGQHTVGDT
                     VKGFAYTDMKQKLRLTTLEVTATQDQFGWGRVTEVRKDLGVFVDTGLPDKEIVVSLDI
                     LPELKELWPKKGDQLYIRLEVDKKDRIWGLLAYQEDFQRLARPAYNNMQNQNWPAIVY
                     RLKLSGTFVYLPENNMLGFIHPSERYAEPRLGQVLDARVIGFREVDRTLNLSLKPRSF
                     EMLENDAQMILTYLESNGGFMTLNDKSSPDDIKATFGISKGQFKKALGGLMKAGKIKQ
                     DQFGTELI"
     gene            15984..16199
                     /locus_tag="VU534_001660"
     CDS             15984..16199
                     /locus_tag="VU534_001660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HEU1514216.1"
                     /translation="MRKSFYTWLMTERNPKSNSPKAILADLAFEESAFPKHTDDFDEV
                     SRFLEEHASFSFNLGDFDSIWQEYLEH"
     gene            16285..17253
                     /locus_tag="VU534_001661"
     CDS             16285..17253
                     /locus_tag="VU534_001661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HEU1514217.1"
                     /translation="MKEHSIDIQLSHPDDLFHLFGSNERHLRLMEEELDVVIHARTEI
                     VQVLGEESACEEARQVIQALMVLVNRGMTVGTPDVVTAISMVKNDEIDKFVALYEEEI
                     IKDNTGKPIRVKTLGQKLYVDSVKQHDVTFGIGPAGTGKTFLAVTLAVTALKRGQVKR
                     IILTRPAVEAGESLGFLPGDLKEKVDPYLRPVYDALYQILGKDQTTRLMEREIIEIAP
                     LAYMRGRTLDDAFVILDEAQNTTIMQMKMFLTRLGFHSKMIVNGDISQIDLPRNVKSG
                     LIDAQEKLKNIHQIDFVHFSAKDVVRHPVVAQIIRAYEYSTEVAHD"
     gene            17322..17744
                     /locus_tag="VU534_001662"
                     /pseudo
     CDS             17322..17744
                     /locus_tag="VU534_001662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558050.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
BASE COUNT         5348 a         3202 c         4177 g         5017 t
ORIGIN      
        1 tgacagaccg tgccaccttg aatggtattt tggagcggac ggacgcctat gcgacaggtt
       61 ctggattttt agatagtgac agtgttaatg gcattacagt tattcgtctc aaggataacc
      121 tagataaccg catggtctat gttaaacgtg aagaagtgga gcttagtcaa gctgggactc
      181 tcttcgtaga agtcatgcaa gaatattttg atcaaaagag gaaatcatga aaaaaagagc
      241 aatagtggca gtcattgtac tgcttttgat tgggctggat cagttggtca aatcctatat
      301 cgtccagcag attccactgg gtgaagtgcg ctcctggatc cccaatttcg ttagcttgac
      361 ctacctgcaa aatcgaggtg cagccttttc tatcttacaa gatcagcagc tgttattcgc
      421 tgtcattact ctggttgtcg tgataggtgc catttggtat ttacataaac acatggagga
      481 ctcattctgg atggtcttgg gtttgactct aataatcgcg ggtggtcttg gaaactttat
      541 tgacagggtc agtcagggct ttgttgtgga tatgttccac cttgacttta tcaactttgc
      601 aattttcaat gtggcagata gctatctgac ggttggagtg attattttat tgattgcaat
      661 gctaaaagag gaaataaatg gaaattaaaa ttgaaactgg tggtctgcgt ttggataagg
      721 ctttgtcaga tttgtcagaa ttatcacgta gtctcgcgaa tgaacaaatt aaatcaggcc
      781 aggtcttggt caatggtcaa gtcaagaaag ctaaatacac agtccaagag ggtgatgtcg
      841 tcacttacca tgtgccagaa ccagaggtat tagagtatgt ggctgaggat cttccgctag
      901 aaatagtcta ccaagatgag gatgtggctg tcgttaacaa acctcaggga atggttgtgc
      961 acccgagtgc tggtcatacc agtggaaccc tagtaaatgc cctcatgtat catattaagg
     1021 acttgtcggg tatcaatggg gttctgcgtc cagggattgt tcaccgtatt gataaggata
     1081 cgtcaggtct tctcatgatt gctaaaaacg atgatgcgca tctagcactt gcccaagaac
     1141 tcaaggataa aaagtctctc cgcaaatatt gggcgattgt tcatggaaat ctacctaatg
     1201 atcgtggtgt aattgaagcg ccgattggcc ggagtgaaaa agaccgtaag aaacaggctg
     1261 taactgctaa agggaagcct gcagtgacgc gttttcacgt cttggaacgc tttggcgatt
     1321 atagcttagt agagttgcaa ctggagacag ggcgcactca tcaaatccgt gtccacatgg
     1381 cttatatcgg ccatccagtc gctggtgatg aggtctatgg tcctcgcaag actttgaaag
     1441 gacatggaca atttcttcat gccaagactt taggttttac tcatccgaga acaggtaaga
     1501 ccttggaatt taaagcagat atcccagaga tttttaagga aaccttggag agattgagaa
     1561 agtaagaatg aaaaagaaat taactagttt agcacttgta ggcgcttttt taggtttgtc
     1621 atggtatggg aatgttcagg ctcaagaaag ttcaggaaat aaaatccact ttatcaatgt
     1681 tcaagaaggt ggcagtgatg cgattattct tgaaagcaat ggacattttg ccatggtgga
     1741 tacaggagaa gattatgatt tcccagatgg aagtgattct cgctatccat ggagagaagg
     1801 aattgaaacg tcttataagc atgttctaac agaccgtgtc tttcgtcgtt tgaaggaatt
     1861 gggtgtccaa aaacttgatt ttattttggt gacccatacc cacagtgatc atattggaaa
     1921 tgttgatgaa ttactgtcta cctatccagt tgaccgagtc tatcttaaga aatatagtga
     1981 tagtcgtatt actaattctg aacgtctatg ggataatctg tatggctatg ataaggtttt
     2041 acagactgct gcagaaaaag gtgtttcagt tattcaaaat atcacacaag gggatgctca
     2101 ttttcagttt ggggacatgg atattcagct ctataattat gaaaatgaaa ctgattcatc
     2161 gggtgaatta aagaaaattt gggatgacaa ttccaattcc ttgattagcg tggtgaaagt
     2221 caatggcaag aaaatttacc ttgggggcga tttagataat gttcatggag cagaagacaa
     2281 gtatggtcct ctcattggaa aagttgattt gatgaagttt aatcatcacc atgataccaa
     2341 caaatcaaat accaaggatt tcattaaaaa tttgagtccg agtttgattg ttcaaacttc
     2401 ggatagtcta ccttggaaaa atggtgttga tagtgagtat gttaattggc tcaaagaacg
     2461 aggaattgag agaatcaacg cagccagcaa agactatgat gcaacagttt ttgatattcg
     2521 aaaagacggt tttgtcaata tttcaacatc ctacaagccg attccaagtt ttcaagctgg
     2581 ttggcataag agtgcatatg ggaactggtg gtatcaagcg cctgattcta caggagagta
     2641 tgctgtcggt tggaatgaaa tcgaaggtga atggtattac tttaaccaaa cgggtatctt
     2701 gttacagaat caatggaaaa aatggaacaa tcattggttc tatttgacag actctggtgc
     2761 ttctgctaaa aattggaaga aaatcgctgg aatctggtat tattttaaca aagaaaacca
     2821 gatggaaatt ggttggattc aagataaaga gcagtggtat tatttggatg ttgatggttc
     2881 tatgaagaca ggatggcttc aatatatggg gcaatggtat tactttgctc catcagggga
     2941 aatgaaaatg ggctgggtaa aagataaaga aacctggtac tatatggatt ctactggtgt
     3001 catgaagaca ggtgagatag aagttgctgg tcaacattat tatctggaag attcaggagc
     3061 tatgaagcaa ggctggcata aaaaggcaaa tgattggtat ttctacaaga cagacggttc
     3121 acgagctgtg ggttggatca aggacaagga taaatggtac ttcttgaaag aaaatggtca
     3181 attacttgtg aacggtaaga caccagaagg ttatactgtg gattcaagtg gtgcctggtt
     3241 agtggatgtt tcgatcgaga aatctgctac aattaaaact acaagtcatt cagaaataaa
     3301 agaatccaaa gaagtagtga aaaaggatct tgaaaataaa gaaacgagtc aacatgaaag
     3361 tgttacaaat ttttcaacta gtcaagattt gacatcctca acttcacaaa gctctgaaac
     3421 gagtgtaaac aaatcggaat cagaacagta gtagaaaaga aggttttagg gccttctttt
     3481 tcctatcaac tcttttctat ttcctgttat tcatgttata atggataaat atgaataatc
     3541 ggagtgagac tatgaaatac aaacggattg tctttaaggt gggtacttct tctctgacaa
     3601 atgaggatgg aagtttatca cgtagtaagg taaaggatat tacccagcag ttggctatgc
     3661 tgcacgaggc tggtcatgag ttgattttgg tgtcttcagg tgccattgcg gctggttttg
     3721 gagccttagg atttaaaaag cgtccgacta agattgctga taaacaggct tcagcagcgg
     3781 tagggcaggg gcttttgttg gaagaatata caaccaatct tctcttgcgt caaatcgttt
     3841 ctgcacaaat cttgctgacc caagatgact ttgtggataa gcgtcgttat aaaaatgccc
     3901 atcaggcttt gtcggttttg ctcaaccgtg gggcaattcc tatcatcaat gagaatgata
     3961 gtgtcgttat tgatgagctc aaggttgggg acaatgacac tctaagtgct caagtagcgg
     4021 cgatggtcca agcagacctt ttagttttct tgacagatgt ggacggtctc tatactggaa
     4081 atcctaattc agatccaaga gccaaacgct tggagagaat cgagaccatc aatcgtgaga
     4141 ttattgatat ggctggtgga gctggttcgt caaacggaac tgggggtatg ttaaccaaaa
     4201 tcaaggctgc aactatcgcg acggaatcag gagttcctgt ttatatctgc tcatccttga
     4261 aatcagattc catgattgag gcggcagagg agaccgagga tggttcttac tttgttgctc
     4321 aagagaaggg gcttcgtacc cagaaacaat ggcttgcctt ctatgctcag agtcaaggtt
     4381 ctatttgggt tgataaaggg gctgcggaag ctctctctca atatggaaag agtcttctct
     4441 tatctggtat cgttgaagca gaaggagtct tttcttacgg tgatatcgtg acagtatttg
     4501 acaaggaaag tggaaaatca cttggaaaag gacgcgtgca atttggagca tctgctttgg
     4561 aggatatgtt gcgttctcaa aaagccaagg gtgtcttgat ttaccgtgac gactggattt
     4621 ccattactcc tgaaatccaa ctacttttta cagaatttta gaggtaaact atggtgagta
     4681 gacaagaaca atttgaacag gtacaggctg ttaaaaaatc gattaacaca gctagtgaag
     4741 aagtgaaaaa ccaagccttg ctagccatgg ctgatcactt agtggctgct actgaggaaa
     4801 ttttagcggc taatgccctc gatatggcag cggctaaggg gaaaatctca gatgtgatgt
     4861 tggatcgtct ttatttggat gcagatcgta tagaagcgat ggcaagagga attcgtgaag
     4921 tggttgcctt accagatcca atcggtgaag ttttagaaac aagtcagctt gaaaatggtt
     4981 tggttatcac aaaaaaacgt gtagctatgg gtgtcatcgg tattatctat gaaagccgtc
     5041 caaatgtgac gtctgatgcg gctgctttga ctcttaagag tggaaatgcg gttgttcttc
     5101 gtagtggtaa ggatgcctat caaacaaccc atgccattgt cacagccttg aagaagggct
     5161 tggagacgac tactattcat ccaaatgtga ttcaactggt ggaggatact agccgtgaaa
     5221 gtagttatgc tatgatgaag gccaagggct atctagacct tctcattcct cgtggaggag
     5281 ctggcttgat caatgcagtg gttgagaatg cgattgtacc tgttatcgag acagggactg
     5341 ggattgtcca tgtctatgtg gataaggatg cagacgaaga caaggcgctg tctatcatca
     5401 acaatgctaa aaccagtcgt ccttctgttt gtaatgccat ggaggttctg ctggttcatg
     5461 aaaacaaggc agcaagcttc cttcctcgct tggagcaagt gttggttgca gagcgtaagg
     5521 aagctggact ggaaccaatt caattccgcc tagatagcaa agcaagccag tttgtttcag
     5581 gtcaagcagc tgagacccaa gactttgaca ccgagttttt agactatgtc cttgctgtta
     5641 aggttgtgag cagtttagaa gaagcggttg cgcacattga atcccacagc acccatcatt
     5701 cggatgctat tgtgacggaa aatgctgaag ctgcagcata ctttacagat caagtggact
     5761 ctgcagcggt gtatgttaat gcctcaactc gtttcacaga tggaggacaa tttggtcttg
     5821 gttgtgaaat ggggatttct actcagaaat tgcacgcgcg tggtcccatg ggcttgaaag
     5881 agttgaccag ctacaagtat gtggttgccg gtgatgggca gataagggag taagagatga
     5941 agattggatt tatcggtttg gggaatatgg gtgctagctt ggcaaaatct gtcttgcaga
     6001 ctaggacgtc agatgagatt ctccttgcca atcgtagtca agctaaggta gatgctttca
     6061 ttgcagactt tggtggtcag gcttccagca atgaagaaat gtttgcagaa gcagatgtga
     6121 tttttctagg agttaagcct gctcagtttt ctgaactgct ttctcaatac cagaccatcc
     6181 ttgaaaaaag agaaagtctt cttttgattt cgatggcagc tggattgacc ttagaaaaac
     6241 tagcaagtct tatcccaagt caacaccgaa ttattcgtat gatgcctaat acccctgctt
     6301 ctatcgggca aggagtgatt agttatgcct tgtctcctaa ttgcagggct gaggacagtg
     6361 agctctttta tcagctttta gccaaggctg gtctcttggt tgaactagga gaaagtttaa
     6421 tcgatgcagc gacaggtctt gcaggttgtg gaccagcctt tgtctatctt tttatcgagg
     6481 ccttggcaga tgcaggtgtt cagacaggat taccacgaga aatagcattg aaaatggcag
     6541 cacaaactgt ggtaggagct gggcaattgg tccttgaaag tcagcaacat cctggagtat
     6601 tgaaagacca agtctgtagc ccaggcggtt cgactatcgc tggtgtagca agcctagaag
     6661 cgcatgcttt ccgaggaaca gtcatggatg cagttcatca agcctacaaa cgaacacaag
     6721 aactaggtaa ataagaggta gttttgactg cctcttttat ggtggctgaa atgagaagac
     6781 acaaaaagat tgtcacaaac ccctattttt ttgatagaat agaagtagta aaaaagaaat
     6841 gagttagaca tgtcaaaagg atttttagtc tctcttgagg gaccagaggg agcaggcaag
     6901 accagtgttt tagaggctct gctaccaatt ttagaggaaa aaggagtaga ggtgttgacg
     6961 acccgtgaac ctggcggagt cttgattggg gagaagattc gggaagtgat tttggatcca
     7021 agtcatactc agatggatgc taaaacagag ctacttctct atattgccag tcgcagacag
     7081 catttggtgg aaaaagttct tccagccctt gaagctggca agttggtcat catggatcgt
     7141 tttatcgata gttctgttgc ctatcaggga tttggtcgtg gcttagatat tgaagccatt
     7201 gactggctca atcagtttgc gacagatggc ctcaaacccg atttgacact ctattttgac
     7261 atcgaggtgg aagaagggct ggctcgtatt gctgctaata gtgaccgcga ggttaatcgt
     7321 ttggatttgg aagggttgga cttgcataaa aaagttcgtc aaggctacct ttctcttctg
     7381 gataaagagg gaaatcgcat tgtcaagatt gatgctagtc tccctttgga gcaagttgtg
     7441 gaaactacca aggctgtctt gtttgacgga atgggcttgg ccaaatgaaa caagatcaac
     7501 taaaggcttg gcaaccagct cagtttgacc gttttgtccg tatcttagaa caagaccagc
     7561 tcaatcacgc ctatctcttt tcaggtttct ttgaaagctt ggaaatggcg caatttttag
     7621 ctaagagcct cttttgtacg gataaagttg gcgtcttacc atgtgagaaa tgccgaagtt
     7681 gcaagctgat tgaacaggga gaatttcccg atgtcacctt gattaaacca gttaatcagg
     7741 tcattaagac ggaacgcatt cgagaattgg tgggtcagtt ttctcaagca gggattgaaa
     7801 gccagcaaca ggtctttatc atcgagcaag cggataaaat gcatcccaac gcagccaatt
     7861 ctctgctcaa ggtcatcgaa gaaccccaga gtgaagttta tattttcttc ttgactagcg
     7921 atgaggaaaa gatgttaccg acaatccgaa gtcggactca gatcttccac tttaaaaagc
     7981 aagaagaaaa acttatctta ctcttagaac aaatgggact tgttaagaaa aaagcgactc
     8041 ttttagctaa gtttagtcaa tcgcgagctg aagcagaaaa gttggctaat caggcaagtt
     8101 tttggacctt ggtcgatgaa agtgaacgcc tgctgacttg gttagtagct aagaaaaaag
     8161 aaagttatct acaggttgcc aaattagcca acttggcaga tgataaggaa aaacaggatc
     8221 aggttttacg gattcttgaa gttctctgtg ggcaggacct cttgcaggta agagtaagag
     8281 tgattctaca agatttacta gaagctagaa aaatgtggca agctaatgtc agctttcaaa
     8341 atgccatgga atatctggtc ttgaaagaaa tataaactca aaaatgaatg ataaagaaag
     8401 gaaagggctg ttttatggac aaaaaagaat tatttgacgc gctggatgat ttttcccaac
     8461 aattattggt aaccttagcc gatgtggaag ccatcaagaa aaatctcaag agcctggtag
     8521 aggaaaatac agctcttcgc ttggaaaata gtaagttgcg agaacgcttg ggtgaggtgg
     8581 aagcagatgc tcctgtcaag gccaagcatg ttcgtgaaag tgtccgtcgc atttaccgtg
     8641 atggatttca cgtatgtaat gatttttatg gacaacgtcg agagcaggac gaggaatgta
     8701 tgttttgtga cgagttgcta tacagggagt aggcatgcag attcaaaaaa gttttaaggg
     8761 gcagtctccc tatggcaagc tgtatctagt ggcaacgccg attggcaatc tagatgatat
     8821 gacttttcgt gctatccaga ccttgaaaga agtggactgg attgctgctg aggatacgcg
     8881 caatacaggg cttttgctca agcattttga catttccacc aagcagatca gttttcatga
     8941 gcacaatgcc aaggaaaaaa ttcctgattt gattggtttc ttgaaagcag ggcaaagtat
     9001 tgctcaggtc tctgatgccg gtttgcctag catttcagac cctggtcatg atttagttaa
     9061 ggcagctatt gaggaagaaa ttgcagttgt gacagttcca ggtgcctctg caggaatttc
     9121 tgccttgatt gccagtggtt tagcgccaca gccacatatc ttttacggtt ttttaccgag
     9181 aaaatcaggt cagcagaagc aattttttgg cttgaaaaaa gattatcctg aaacacagat
     9241 tttttatgaa tcacctcatc gtgtagcaga cacgttggaa aatatgttag aagtctacgg
     9301 tgaccgctcc gttgtcttgg tcagggaatt gaccaaaatc tatgaagaat accaacgagg
     9361 tactatctct gagttattag aaagcattgc tgaaacgcca ctcaagggcg aatgtcttct
     9421 cattgttgag ggtgccagtc agggtgtgga ggaaaaggac gaggaagact tgttcgtaga
     9481 aattcaaacc cgcatccagc aaggtgtgaa gaaaaaccaa gctatcaagg aagtcgctaa
     9541 gatttaccag tggaataaaa gtcagctcta cgctgcctac cacgactggg aagaaaaaca
     9601 ataaagggag acaggatgta ataattctgt ctgtttctgt ttaacttaat tagtgatgat
     9661 aatataaaga tgtatcactt ggtatagaag ctttggtatt aagtttttta ttaagcccat
     9721 acggaatacc gatggttgga gcagcagtta tagcgttctt agaaggtata aatagaaaaa
     9781 taaggtcatt ttaaatcaaa ggattgataa atcagaaaga aggtgatttt ttgcgaacat
     9841 acgaaaataa agaagaacta aaagctgaga tagagaaaac atttgagaaa tatattttag
     9901 aatttgataa tattccagaa aatttaaaag ataagagagc tgatgaagtt gacagaactc
     9961 cagcagaaaa ccttgcttat caggttggtt ggaccaactt ggttcttaaa tgggaagaag
    10021 atgaaagaaa ggggcttcaa gtaaaaacac catcggataa atttaaatgg aatcaacttg
    10081 gtgaattata tcagtggttc acagatacct acgctcattt atctctgcaa gagttgaaag
    10141 caaaattaaa tgaaaatatt aattctatct ctgcaatgat tgattcgttg agtgaggaag
    10201 aattatttga accgcatatg agaaagtggg ctgatgaagc gactaaaaca gcgacttggg
    10261 aagtgtataa gtttattcat gtaaatacgg ttgcaccttt tggaactttc agaactaaaa
    10321 tcagaaaatg gaagaagata gtattataaa ttatattttt aactttaaaa aatttcataa
    10381 aaatggttac caaaggcgat agaagaaaaa ctattgtctt tttctttgca aatttttaag
    10441 aagggaggtg atcttgcatg gactttgaat atttttataa cagagaagcg gaaagattta
    10501 acttcttaaa agtaccggag atattagttg atagagaaga atttcggggc ttatcagcag
    10561 aagcaattat cctttattcc atacttctta aacagacagg aatgtcattt aagaataact
    10621 ggatagacaa ggaaggcaga gtatttatct attttactgt cgaagaaatt atgaaaagaa
    10681 gaaatatctc aaagccaact gccataaaaa cattagatga gcttgatgta aaaaaggaat
    10741 aggactgatc gaaagagtaa ggcttggact tggtaagccg aacatcattt atgttaaaga
    10801 ctttatgagt atatttcagg taaaagaaaa tgacttacag aagtcaaaaa acttaacttc
    10861 agaagtaaaa gattttaacc tcagaagtaa agaaaatgaa cttcaagagg ttaagaacct
    10921 tgactctaac tatatagaga ataataagag taagtatagt aagagagaat atagttttgg
    10981 tgaaaacgga cttggaacat ttcaaaatgt gtttttagct gctgaagata tatcggattt
    11041 acaaatcata atgaactcac agcttgagaa ttacattaga cttcctgcaa aactagaatc
    11101 ctagttcatg attgataatg ccagcaatca aattcattcg taatccgaag cgtttacgat
    11161 gatttcgata gattgttgaa aacattttaa acgtttttac tttggcaaag atgttctcaa
    11221 tcttgcttct ctccttggat agcgcatggt tacaggcttt atcttcagct gttagcggct
    11281 tgagtttgct ggatttacgt ggagtttgta cttgaggata tatcttcatg agcccttgat
    11341 aaccactgtc agacaagatt ttaccagctt gtccgatatt tctgcgactc attttgaaca
    11401 acttcatatc acgacaatag ttcacagcga tatccaaaga aacaattctc ccttgacttg
    11461 tgacaatcgc ttgagccttc atagcgtgaa atttcttttt accagaatga ttcgctaatt
    11521 ctttttttag ggcgattgat ttttacttcc gtcgcatcaa tcattaccgt gtcctcagaa
    11581 ctgagaggag ttcttgaaat cgtaacacca ctttgaacaa gagttacttc aacccattgg
    11641 ctccgacgga ttaagttgct ttcgtgaata ccaaaatcag ccgcaatttg ttcataagtt
    11701 cgatattctc gcacatattg aagagtggcc ataagaaggt cttctaggct taatttaggt
    11761 tttcgtccac cttttgcgtg tttaagttga taagctgttt ttaatacagc taatatctct
    11821 tcaaaagtcg tgcgctgaac accaacaaga cgcttaaatc gtgcatcagt tagttgttta
    11881 cttgcttcat cattcataga actactatac catattttgt ttcgcaggaa gtctattgga
    11941 aagtaagaaa tattgaagct gaggctatta gaagaaattg tgagcgtggt gctatttttt
    12001 caggtaaaat aaaatatcac gaagattcac agtttaaagg agatcactat gttgaatgtt
    12061 atgctgtttt agataatacg gttatagcaa gagatagaat aacagtccct atcgatccgt
    12121 tatgtggaaa agattttata gagtagcata taattgattc ttaactggaa tactcactat
    12181 ctctttacat caagaaaatg actaaacagg gaagtttgcc ttcttccctt tttttgttat
    12241 actagtagaa gaaaaaatta gaaagatttg tgggtgtcaa acagcccagt ggggtgtttt
    12301 aatatggact taggtcccac ccaaagaggt attagtgtcg tgtctcaatc ttatatcaat
    12361 gttatcggtg ctggtttggc aggttctgaa gcagcttacc aaatcgcaga gcgtggtatt
    12421 ccagttaaac tatatgaaat gcgtggtgtc aagtctacac cccagcataa aacagacaat
    12481 tttgctgagt tggtttgttc caattctttg cgtggggatg ctttgacaaa tgcagttggt
    12541 cttctcaagg aagaaatgcg tcgcttgggt tctgttatct tggaatctgc tgaggctaca
    12601 cgtgttcctg caggtggtgc ccttgcagtg gaccgtgatg gtttctctca aatggtgacc
    12661 gaaaaagttg ccaaccaccc cttgattgaa gtggttcgtg atgaaattac agaattgccg
    12721 acagatgtta ttacggttat cgctactggt cctttgacaa gtgatgcctt ggctgaaaag
    12781 attcatgctc ttaatgacgg tgctggtttt tatttctacg atgcggcagc gcctattatc
    12841 gatgtcaaca ctatcgatat gagcaaggtc tacctcaaat cacgttatga taagggagaa
    12901 gcggcctacc tcaatgcccc tatgaccaag caagaattta tggatttcca tgaagctttg
    12961 gtcaatgcag aagaagcacc gcttagttct tttgaaaaag aaaagtactt tgaaggatgt
    13021 atgcctatcg aagtcatggc caaacgtggc attaaaacta tgctttatgg ccctatgaag
    13081 ccagtcggtc ttgagtaccc agacgactat acaggacctc gtgatggaga atttaaaaca
    13141 ccttatgcgg ttgtgcaact tcgtcaggat aatgcagctg gtagcctcta caatattgtt
    13201 ggtttccaga cccacctcaa atggggagaa caaaagcgtg tcttccaaat gattccgggt
    13261 cttgaaaatg cggagtttgt ccgttatggt gtgatgcatc gcaattctta catggattca
    13321 ccaaatcttc ttgagcagac ttaccgttct aagaaacaac caaatctctt ctttgctggt
    13381 caaatgacgg gtgtggaagg ctatgttgag tcggcggctt caggcttagt tgcgggaatt
    13441 aacgcagctc gtctcttcaa ggaagaaagc gaggctattt tccccgagac gacagcgatt
    13501 ggaagcttag ctcattacat tacccatgcc gacagcaaac atttccaacc aatgaatgtc
    13561 aattttggga tcatcaagga gttggaaggc gagcgtatcc gtgataagaa ggctcgttat
    13621 gaaaaaattg cagagcgtgc ccttgccgac ttagaggaat ttttgactgt ctaatttttt
    13681 tgaaagaatt gctcatgata ctataaaaat cttagaaatt gtgataaaat aggtaggatg
    13741 aaagaaggag agtgaaaatg gcgaatccca agtataaacg tattttaatc aagttatcag
    13801 gtgaagccct tgccggtgaa cgtggcgtag ggattgatat ccaaacagtt caaacaatcg
    13861 caaaagagat tcaagaagtt catagcttag gtatcgaaat tgcccttgtt atcggtggag
    13921 gaaatctctg gcgtggagaa cctgcagcag aagcaggtat ggaccgtgtt caggcagatt
    13981 acacaggaat gcttgggact gttatgaatg ctcttgtgat ggcagattca ttgcaacaag
    14041 ttggggttga tacgcgtgta caaacagcta ttgccatgca acaagtggca gagccttatg
    14101 tccgtggacg tgcccttcgt caccttgaaa aaggccgtat cgttatcttt ggtgctggaa
    14161 ttggttcacc ttacttctcg acagatacaa cagcggccct tcgtgcagct gaaatcgaag
    14221 cagatgccat cctcatggct aaaaatggtg tcgatggtgt ttacaatgcc gatcctaaga
    14281 aagataagac agctgttaag tttgaagaat tgacccaccg tgacgttatc aataaaggtc
    14341 ttcgtatcat ggactcaaca gcttcaaccc tctcaatgga caacgacatt gacttggttg
    14401 tattcaacat gaaccaacca ggcaacatca aacgtgtcgt atttggtgaa aatatcggaa
    14461 caacagtttc aaataatatc gaagaaaagg aataagaaag aatatggcta acgcaattat
    14521 tgaaaaagct aaagagagaa tgacccagtc tcaccaatca cttgctcgtg aatttggtgg
    14581 tatccgtgct ggtcgtgcca atgcaagctt gcttgaccgt gtacatgtag aatactatgg
    14641 agtcgaaact cctcttaacc aaatcgcttc aattacgatt ccagaagcgc gtgttttgtt
    14701 ggtaacacca tttgacaagt cttcattgaa agacatcgaa cgtgccttga acgcttctga
    14761 tattggtatc acaccggcta atgacggttc tgtgattcgc ttggttatcc cagctcttac
    14821 agaagaaact cgtcgtgacc ttgctaaaga agtgaagaag gtcggcgaaa atgctaaagt
    14881 ggctgtccgc aatatccgtc gcgatgctat ggacgaagct aagaaacgag aaaaagcaaa
    14941 agaaatcact gaagacgaat tgaagactct tgaaaaagac attcaaaaag taacagacga
    15001 tgctgttaaa cacatcgacg acatgactgc taacaaagag aaagaacttt tggaagtcta
    15061 aaaataaaca gaaaaactca gttggcattg ctggctgagt tttattcgaa agaaggaaat
    15121 atgaatacaa atcttgcaag ttttatcgtt ggactgatca tcgatgaaaa cgaccgtttt
    15181 tactttgtgc aaaaggatgg tcaaacctat gctcttgcta aggaagaagg ccaacataca
    15241 gtaggggata cggtcaaagg ttttgcatac acggatatga agcaaaaact ccgcctgaca
    15301 accttagaag tgactgccac tcaggaccaa tttggttggg gacgtgtcac agaggttcgt
    15361 aaggacttgg gtgtctttgt ggatacaggc cttcctgaca aggaaatcgt tgtgtcactc
    15421 gatattctcc ctgagctcaa ggaactctgg cctaagaagg gcgaccaact ctacatccgt
    15481 cttgaagtgg ataagaaaga ccgtatctgg ggcctcttgg cttatcaaga agacttccaa
    15541 cgtcttgctc gtcctgccta caacaacatg cagaaccaaa actggccagc cattgtttac
    15601 cgtctcaagc tgtcaggaac ttttgtttac ctaccagaaa ataatatgct tggttttatt
    15661 catcctagcg agcgttacgc agagccacgt ttggggcaag tattagatgc gcgcgttatt
    15721 ggtttccgtg aagtggaccg cactctgaac ctctccctca aaccacgctc ctttgaaatg
    15781 ttggaaaacg atgctcagat gattttgact tatttggaaa gcaatggcgg tttcatgacc
    15841 ttaaatgaca agtcatctcc agacgacatc aaggcaacct ttggcatttc taaaggtcag
    15901 ttcaagaaag ctttaggtgg tcttatgaag gctggtaaaa tcaagcagga ccagtttggg
    15961 acagagttga tttagggagg cttatgagaa aatcatttta cacttggctc atgaccgagc
    16021 gcaatcctaa aagtaacagt cccaaagcaa ttttggcaga cctcgctttt gaagagtcag
    16081 cctttccaaa acacacagat gattttgatg aggtcagtcg ctttttggag gagcatgcca
    16141 gtttctcttt taacctagga gattttgaca gcatttggca ggaatatcta gaacactagc
    16201 atttattcat tgggtttggg ctagtaattt ctccatccct ctgctataat aaaaagaaat
    16261 aaaaggatta gagaggttct ttatttgaag gaacattcaa tagacattca actgagtcat
    16321 ccagatgacc tgtttcatct ttttggttcc aatgaacgcc atcttcgttt gatggaagaa
    16381 gagcttgatg ttgtgattca tgctcgtacg gagattgtcc aggttttggg agaagagtct
    16441 gcctgtgagg aagcccgtca agttattcag gctttgatgg tcttggtaaa tcgtgggatg
    16501 accgttggta cgccagatgt agtcactgcg attagcatgg tcaaaaatga tgaaattgac
    16561 aagtttgtcg ccctttacga agaagaaatt atcaaggata atactgggaa acctatccgt
    16621 gtcaaaaccc tagggcaaaa gctttatgtg gacagtgtca aacagcatga tgtgaccttt
    16681 ggaattgggc cagcaggtac agggaagacc ttccttgcag tgaccttggc agtgactgcc
    16741 cttaaacgtg ggcaagtcaa gcgaattatc ctaactcgtc cagcggtgga agcgggagag
    16801 agtcttggat ttcttccggg tgatcttaag gagaaggtgg atccttacct tcgtcctgtt
    16861 tacgatgcct tgtatcaaat tcttgggaaa gaccaaacga ctcgtctcat ggagcgtgaa
    16921 attatcgaaa ttgcgcccct tgcctatatg cgtggccgga ccttggatga tgcctttgtc
    16981 attctcgatg aggcgcaaaa cacgaccatc atgcagatga agatgttctt gacgcgttta
    17041 ggttttcatt ctaagatgat tgtcaatgga gatattagtc agattgacct gccacgtaat
    17101 gtcaagtccg gtttgattga tgctcaagag aaactcaaga acatccatca gattgacttt
    17161 gttcattttt cagccaagga tgtggttcgc catcctgttg tcgctcagat tatccgagcc
    17221 tatgaatatt ctactgaagt tgcacacgac tgattttgag gaagttcgcc tgcaaaagaa
    17281 tagacttgtt cggtaactgt aaaaagtgtt atactatttt tatggaaaca gtatacgaca
    17341 aagcacaaaa acttaactca aaaaacttca aactattgat tggtgtcaaa aaggaaacct
    17401 ttcaactcat gctagaacac ctgaattcag cctatcagat tcagcaccga aaaggtggac
    17461 gtccacgtag tctgcccatg gaagaccagc tcattatgac cctccgttac ttgcgatatt
    17521 atcccactca gcgtctgctg gcctttgatt ttggcgtcgg tgtagctacg gtaaatgcca
    17581 tcatcacttg ggtggaggat acacttcgtg cgtcaggtag ctttgatttg gaccatttag
    17641 aagccccgag tgctgctgtg gctattgacg tgaccgaaag tccgattcag cgtccaaaca
    17701 aaaccaaagc aaaaattatt ctggtaaaaa gaaacgacac acct
//
LOCUS       DAVFER010000045        16994 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1105170250
            SAMEA2167659-rid19724873.denovo.045, whole genome shotgun sequence.
ACCESSION   DAVFER010000045 DAVFER010000000
VERSION     DAVFER010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2167659
            Sequence Read Archive: ERR388902
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 16994)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16994)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928716.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928716.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 04:07:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,118
            CDSs (total)                      :: 2,073
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 120
            CDSs (without protein)            :: 120
            Pseudo Genes (ambiguous residues) :: 0 of 120
            Pseudo Genes (frameshifted)       :: 67 of 120
            Pseudo Genes (incomplete)         :: 47 of 120
            Pseudo Genes (internal stop)      :: 34 of 120
            Pseudo Genes (multiple problems)  :: 23 of 120
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16994
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2167659-rid19724873.denovo.045"
                     /strain="1105170250"
                     /db_xref="taxon:1313"
     gene            complement(124..471)
                     /locus_tag="VU534_001663"
     CDS             complement(124..471)
                     /locus_tag="VU534_001663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003017645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEU1514218.1"
                     /translation="MNLNQLDIIVSNVPQVCADLEHILDKKADYANDGFAQFTIGSHC
                     LMLSQNHLVPLENFQSGIIIHIEVEDVDQNYKRLNELGIKVLHGPTVTDWGTESLLVQ
                     GPAGLVLDFYRMK"
     gene            complement(582..2357)
                     /gene="spxB"
                     /locus_tag="VU534_001664"
     CDS             complement(582..2357)
                     /gene="spxB"
                     /locus_tag="VU534_001664"
                     /EC_number="1.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000191798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate oxidase"
                     /protein_id="HEU1514219.1"
                     /translation="MTQGKITASAAMLNVLKTWGVDTIYGIPSGTLSSLMDALAEDKD
                     IRFLQVRHEETGALAAVMQAKFGGSIGVAVGSGGPGATHLINGVYDAAMDNTPFLAIL
                     GSRPVNELNMDAFQELNQNPMYNGIAVYNKRVAYAEQLPKVIDEACRAAVSKKGPAVV
                     EIPVNFGFQEIDENSYYGSGSYERSFIAPALNEVEIDKAVEILNNAERPVIYAGFGGV
                     KAGEVITELSRKIKAPIITTGKNFEAFEWNYEGLTGSAYRVGWKPANEVVFEADTVLF
                     LGSNFPFAEVYEAFKNTEKFIQVDIDPYKLGKRHALDASILGDAGQAAKAILDKVNPV
                     ESTPWWRANVKNNQNWRDYMNKLEGKTEGELQLYQVYNAINKHADQDAIYSIDVGNTT
                     QTSTRHLHMTPKNMWRTSPLFATMGIALPGGIAAKKDNPDRQVWNIMGDGAFNMCYPD
                     VITNVQYDLPVINLVFSNAEYGFIKNKYEDTNKHLFGVDFTNADYAKIAEAQGAVGFT
                     VDRIEDIDAVVAEAVKLNKEGKTVVIDARITQHRPLPVEVLELDPKLHSEEAIKAFKE
                     KYEAEELVPFRLFLEEEGLQSRAIK"
     gene            complement(2564..4807)
                     /locus_tag="VU534_001665"
     CDS             complement(2564..4807)
                     /locus_tag="VU534_001665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HEU1514220.1"
                     /translation="MTEIVKASLENGIQKIRIRAEKGYHPAHIQLQKGIPAEITFHRA
                     TPSNCYKEILFEEEGILEPIGVDEEKVIRFTPQELGRHEFSCGMKMQKGSYTVVEKTR
                     KSLSLLQRFWITSIFTVPLVILMIGMLTGSISHQVMHWGTFLATTPIMLVAGKPYIQS
                     AWASFKKHNANMDTLVALGTLVAYFYSLVALFAGLPVYFESAGFILFFVLLGAVFEEK
                     MRKNTSQAVEKLLDLQAKTAEVLSDDSYVQVPLEQVKVGDLIRVRPGEKIAVDGVVVE
                     GVSSIDESMVTGESLPVDKTVGDTVIGSTINHSGTLVFRAEKVGSETVLAQIVDFVKK
                     AQTSRAPIQDLTDKISGIFVPVVVILGIMTFWVWFVLLRDSVVVLGASFVSSLLYGVA
                     VLIIACPCALGLATPTALMVGTGRSAKMGVLLKNGTVLQEIQKVQTLVFDKTGTLTEG
                     KPVVTDVIGDEVEVFGLAASLEDASQHPLAEAIVKRASEAGLEFQTVENFQSLHGKGV
                     SGRINGKQVLLGNAKMLDGMDISNTYQDKLEELEKEAKTVVFLAVDNEIKGLLALQDI
                     PKENAKLAISQLKKRGLRTVMLTGDNAGVARAIADQIGIEEVIAGVLPEEKAHEIHKL
                     QQSGKVAFVGDGINDAPALSVADVGIAMGAGTDIAIESADLVLTTNNLLGVVRAFDMS
                     KKTFHRILLNLFWAFIYNVVGIPIAAGVFSGVGLALNPELAGLAMAFSSVSVLTSSLL
                     LNFSKID"
     gene            complement(4817..5188)
                     /locus_tag="VU534_001666"
     CDS             complement(4817..5188)
                     /locus_tag="VU534_001666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000932058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupredoxin domain-containing protein"
                     /protein_id="HEU1514221.1"
                     /translation="MLNSIVTIICIALIAFILFWFFKKPEKSGQKAQQKNGYQEIRVE
                     VMGGYTPELIVLKKSVPARIVFDRKDPSPCLDQIVFPDFGVHANLPMGEEYVVEITPE
                     QAGEFGFACGMNMMHGKMIVE"
     gene            complement(5199..5594)
                     /locus_tag="VU534_001667"
     CDS             complement(5199..5594)
                     /locus_tag="VU534_001667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopY/TcrY family copper transport repressor"
                     /protein_id="HEU1514222.1"
                     /translation="MQISDAEWQVMKIIWMQGEQTSTDLIRVLAERFDWSKSTVQTLL
                     ARLVDKECLTRKKEGKSFVYSALLTLDQSRDLLVQDIKDKVCSRRIRNLLADLIVECE
                     FTQTDLEDLEAVISEKKSSAVTEVRCNCM"
     regulatory      5778..5876
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            5960..6751
                     /gene="thiD"
                     /locus_tag="VU534_001668"
     CDS             5960..6751
                     /gene="thiD"
                     /locus_tag="VU534_001668"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HEU1514223.1"
                     /translation="MTYLPVALTIAGTDPSGGAGIMADLKSFQARDVYGMAVVTSLVA
                     QNTRGVQLIEHVSPQMLKAQLESVFSDIPPQAVKTGMLATTEIMEIIQPYLKKLDCPY
                     VLDPVMVATSGDALIDSNARDYLKTNLLPLATIITPNLPEAEEIVGFSIHDPEDMQRA
                     GRLILKEFGPQSVVIKGGHLKGGAKDFLFTKNEQFVWESPRIQTCHTHGTGCTFAAVI
                     TAELAKGKSLYQAVDKAKAFITKAIQDAPQLGHGSGPVNHTTFKD"
     gene            complement(6961..7593)
                     /locus_tag="VU534_001669"
     CDS             complement(6961..7593)
                     /locus_tag="VU534_001669"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001078228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HEU1514224.1"
                     /translation="MNREALRLYLVTNRYQDSVESFLAKVETACRSGVTIVQLREKNL
                     TTNQYYQLAKQVKEITDAYQVPLIIDDRLDVCLAVDAAGLHIGDDELPVSVARKVLGP
                     EKILGVTAKTVKRALEAEKSGADYLGTGAIFPTTTKENAPITLISTLKTICQTVAIPV
                     VAIGGLTSENIDQLMGTGIAGVAVVRDLMQAEDIEAKTQAFLKKLHNILS"
     gene            complement(7586..8389)
                     /locus_tag="VU534_001670"
     CDS             complement(7586..8389)
                     /locus_tag="VU534_001670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HEU1514225.1"
                     /translation="MQEFTNPFPIGSSSLIHCITNEISCEMLANGILALGCKPVMADD
                     SREVLDFTKQSQALFINLGHLSAEKEKAIRMAASYANQSSLPMVVDAVGVTTSSIRKS
                     LVKDLLDYRPTVLKGNMSEIRSLVGLKHHGVGVDASAKDQETEDLLQVLKDWCQTYPG
                     MSFLVTGPKDLVVSKNQVAVLGNGCTELDWITGTGDLVGALTAVFLSQGKTGFEASCL
                     AVSYLNIAAEKIVVQGMGLEEFRYQVLNQLSLLRRDENWLDTIKGEVYE"
     gene            complement(8389..8913)
                     /gene="thiW"
                     /locus_tag="VU534_001671"
     CDS             complement(8389..8913)
                     /gene="thiW"
                     /locus_tag="VU534_001671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001225563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy coupling factor transporter S component
                     ThiW"
                     /protein_id="HEU1514226.1"
                     /translation="MRKHQLQVHKLTILSMMIALDVVLTPIFRIEGMAPMSSVVNILA
                     GIMMGPVYALAMATVTAFIRMTTQGIPPLALTGATFGALLAGLFYKYGRKFHYSALGE
                     ILGTGIIGSIVSYPVMVLFTGSAAKLSWFIYTPRFFGATLIGTAISFIAFRFLIKQEF
                     FKKVQGYFFSERID"
     gene            complement(8918..9610)
                     /gene="tenA"
                     /locus_tag="VU534_001672"
     CDS             complement(8918..9610)
                     /gene="tenA"
                     /locus_tag="VU534_001672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiaminase II"
                     /protein_id="HEU1514227.1"
                     /translation="MEFTDIAMELSKKAWQASFHHPFILQLQEGNLEPAIFRYYLIQD
                     AYYLKAFSEIYHLLADKTSNQEMKRLLKQNAQGLVEGELFIRQQFFKELEISDQEMEQ
                     HPIAPTCYHYISHIYRQFAEPNLAIAFASLLPCPWLYHDIGKSLNLKPSPNPLYQQWI
                     ETYITDELEQQIREEGALVNQLYRESDETDKQKMLDAFHISVHMEAKFWEMAYQHQTW
                     KSDLQSLEKGEE"
     gene            complement(9621..10271)
                     /locus_tag="VU534_001673"
     CDS             complement(9621..10271)
                     /locus_tag="VU534_001673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt ABC transporter permease"
                     /protein_id="HEU1514228.1"
                     /translation="MVKVATQTPIISLFLLILSLETSFIPSIALTLSVVAFCILFMLY
                     YRRFKMLAWMIILAILPSFANYWAVQLHGDASQAVMLGTRAFVTVCIGLVFVSSVSLK
                     ELLLYLAQKGLSRSWSYALIVVFNSFPLIQQEIKSLKEACLLRGQELHFWSPLIYSKV
                     LMTVFRWRHLYLRALSAHGYDEHAQLKNSYRTFYIPKKTKLIYLLFFLLLQTSLFL"
     gene            complement(10273..11658)
                     /locus_tag="VU534_001674"
     CDS             complement(10273..11658)
                     /locus_tag="VU534_001674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU1514229.1"
                     /translation="MGLELRAIQSPIFSEPFDFTFHAQAFTLLVGSSGSGKSSLFQMI
                     AQVSSLPYSGQVLIDGSEVSQLSIVERVQTVGILLQNPNHQFTMESLFEELVFTMENI
                     GYHLQEIDSKIAEVVQQCRCKDILHRLIHHLSGGEKQKAALAVLFAMNPRVYLLDEPF
                     ASIDRKSRIEILEILKELVYDGKTVILCDHDLSDYKAYIDHMVELRDGKLREVFQIPS
                     YEMTQVASKEVASSPELFHMNRVTGELGNRPLFSIADFTFYQGISCILGDNGVGKSTL
                     FRSILQFQKYKGSITWKGSVLKKKKSLYRDLTGVVQEAEKQFIRVSLREELQLDGPDS
                     ERNQRIFQALRYFDLEQAVDKSPYQLSGGQQKILQLLTILTSKASVILLDEPFAGLDD
                     RACHYFCKWIVEERNQGRSFLLISHRLDPLISVVDYWIEMTSQGLRHVKEVTITKPLT
                     SQSSNTQGEVR"
     gene            complement(11659..12219)
                     /locus_tag="VU534_001675"
     CDS             complement(11659..12219)
                     /locus_tag="VU534_001675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000915269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEU1514230.1"
                     /translation="MLKKWQLKDVILLAFLSIFFGGVFVGSGYVYNILSLLLTPLGLQ
                     AFANEILFGLWCMAAPIAAIFVPRVGSATIGEVLAALAEVLYGSQFGLGALLSGFVQG
                     LGSEFGFIVTKNRYESWLSLTANSIGITLVSFVYEYIKLGYYAFSLPFVLSLLVVRFI
                     SVYFFCTILVRAIVKLYHQFATGGKA"
     regulatory      complement(12481..12569)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(12778..13407)
                     /locus_tag="VU534_001676"
     CDS             complement(12778..13407)
                     /locus_tag="VU534_001676"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000468574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HEU1514231.1"
                     /translation="MFHKELLKLYFICGTTTCQGKNLYTVVEEALKGGITLFQFREKG
                     EGALEGLEKLELAIQIKELCKKYNVPFIVNDDIDLAMEIDADGVHVGQDDIGVDEIRK
                     LMPDKIIGLSIRNEEEFQQSKVEYVDYVGVGPVFGTQSKDDAGGTIGYEGLELMRKLL
                     PQMPLVAIGGIQTKHIKDIIKTNMDGVSIISAISYAKNIEKTVREMSEQ"
     gene            complement(13409..14191)
                     /gene="thiM"
                     /locus_tag="VU534_001677"
     CDS             complement(13409..14191)
                     /gene="thiM"
                     /locus_tag="VU534_001677"
                     /EC_number="2.7.1.50"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000202454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HEU1514232.1"
                     /translation="MTSLKLLKEKAPLVICITNDVVKNFTANGLVALGASPAMSEFPA
                     DLEDLLKYAGGLLINIGTLTDENWKLYQAALKIAEKYNVPAVLDPVACGAGEYRKKVA
                     DDLINNYKLAAIRGNAGEIASLVGIDVASKGVDSAGVDNIDEIALAANEKFNIPIVVT
                     GEVDAIAVNGEVVMIHNGSAMMPKVIGTGCLLGAVVASFIGLEKGQELKSLKTAVLVY
                     NIAGEIAEKRPNGHLPGTFKVEFINALYEITDEDVKEFKRVK"
     gene            complement(14428..15096)
                     /locus_tag="VU534_001678"
     CDS             complement(14428..15096)
                     /locus_tag="VU534_001678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000449895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TenA family protein"
                     /protein_id="HEU1514233.1"
                     /translation="METQDYAFQPGLTVGELLKSSQKDWQAAINHRFVKELFAGTIEN
                     KVLKDYLIQDYHFFDAFLSMLGACVAHADKLESKLRFAKQLGFLEADEDGYFQKAFKE
                     LKVAENDYLEVTLHPVTKAFQDLMYSAVASSDYAHLLVMLVIAEGLYLDWGSKDLALP
                     EVYIHSEWINLHRGPFFAEWVQFLVDELNRVGKNREDLTELQQRWNQAVALELAFFDI
                     GYDV"
     regulatory      complement(15311..15399)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(15653..16789)
                     /gene="lctO"
                     /locus_tag="VU534_001679"
     CDS             complement(15653..16789)
                     /gene="lctO"
                     /locus_tag="VU534_001679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate oxidase"
                     /protein_id="HEU1514234.1"
                     /translation="MSYKTSNAEGHVDFINTYDLEPMAQQVIPKAAFGYIASGAEDTF
                     TLRENIRAFNHKLIVPHTLCNVENPSTEIEFAGEKLSSPIIMAPVAAHKLANEQGEVA
                     TARGVHEFGSLYTTSSYSTVDLPEISEALQGTPHWFQFYFSKDDGINRHIMDRVKAEG
                     YKAIVLTADATVGGNREVDKRNGFVFPVGMPIVEEYLPEGAGKSMDFVYKSAKQRLSP
                     RDVEFIAEYSGLPVYVKGPQCREDVERSLAAGASGIWVTNHGGRQIDGGPAAFDSLQE
                     VAEAVDRRVPIVFDSGVRRGQHVFKALASGADLVAIGRPVIYGLALGGSVGVRQVFEH
                     LNAELKTVMQLSGTQTIEDVKHFKLRHNPYNPTFPVDPRDLKLY"
BASE COUNT         5107 a         3771 c         3104 g         5012 t
ORIGIN      
        1 cagatgagta ttatatgcaa tttctttata taaaaagacc ggattgctcc gatctttcaa
       61 tagttcatat tctcaatttc tattttaaaa atagctaagg ttaacgtcaa atgactacgc
      121 gacctatttc atacgataaa aatcaagcac tagaccagca ggtccttgaa ctaataagga
      181 ctctgttccc caatcggtta cagttggtcc gtgtaaaacc tttataccaa gctcgttcaa
      241 ccgtttgtag ttctggtcta catcctcaac ctcgatatga ataatgattc ctgactgaaa
      301 gttttccaaa ggaaccaaat gattttgtga caacataagg cagtgactac caatcgtaaa
      361 ctgagcaaaa ccatcattag cataatctgc ctttttatcc aagatatgct ccaagtcagc
      421 acagacttgg ggaacatttg aaacgataat atctaattga tttaaattca tttactctcc
      481 tccataaaaa gaccggattg ctccgatctt ttaaagttct gctctatgaa aatcaaagaa
      541 taaagtctac aagtttcata tttgattttc ggcgagagga attatttaat tgcgcgtgat
      601 tgcaatcctt cttcttccaa gaagagacgg aatggtacga gttcttctgc ttcgtatttt
      661 tccttgaagg ctttgatagc ttcttctgag tgaagttttg gatccaattc aagtacttct
      721 actggaagtg gacggtgttg agtgatgcga gcatcgatga caacagtttt accttctttg
      781 ttcaatttaa cagcttctgc aacaactgca tcgatgtctt cgatacggtc aactgtgaat
      841 ccaacagctc cttgagcttc cgcaatttta gcgtagtcag cgtttgtgaa gtctacacca
      901 aacaagtgtt tgtttgtatc ttcgtatttg ttcttgatga agccgtactc agcatttgag
      961 aagacaaggt tgataactgg aaggtcgtat tgaacgtttg tgataacgtc tgggtagcac
     1021 atgttgaatg ctccgtcacc catgatgttc catacttggc gatctggatt gtctttctta
     1081 gcagcgatac caccaggaag ggcaataccc attgtcgcaa agagtggaga tgtacgccac
     1141 atgttcttag gtgtcatgtg aaggtgacga gtagatgttt gagtagtgtt acctacgtcg
     1201 attgagtaga tagcgtcttg atcagcatgt ttgttgattg cattgtaaac ttgatacaat
     1261 tgcaattcac cctcagtttt accttcgagt ttgttcatgt aatcacgcca gttttggttg
     1321 ttcttaacgt ttgcacgcca ccatggagtt gattcaactg ggtttacttt gtcaaggata
     1381 gctttagctg cttgaccagc atcaccaagg attgaagcgt caagggcatg acgtttacca
     1441 agtttgtaag ggtcgatatc gacttggatg aatttttcag tgttcttgaa tgcttcgtaa
     1501 acttcagcaa atgggaagtt tgaaccaagg aaaagaactg tgtctgcttc aaagaccact
     1561 tcgttggctg gtttccaacc aacacggtaa gcagaacctg tcaaaccttc atagttccat
     1621 tcgaaagctt caaagttttt accagttgtg atgattggtg ctttgatttt acgtgacaat
     1681 tcagtaatca cttcaccagc tttaacacca ccaaatccag catagataac tgggcgttca
     1741 gcattgttca agatttcaac agctttgtcg atttcaactt cgttcaaagc aggagcgatg
     1801 aatgagcgtt cgtatgaacc tgaaccgtag tatgagtttt catcgatttc ttggaaaccg
     1861 aagtttactg gaatttcaac aacagctgga ccttttttag aaactgcagc acggcaggct
     1921 tcgtcaatta cttttggcaa ttgctcagcg taagctacac gtttgttgta aacagcgata
     1981 ccgttgtaca ttgggttttg gttaagctct tggaaagcat ccatgttcaa ttcgttaact
     2041 ggacgtgatc caaggatcgc taggaatgga gtgttatcca tagctgcatc gtaaacaccg
     2101 ttaatcaagt gagtcgcacc tggaccacct gaaccaactg caaccccgat tgagccgccg
     2161 aatttagctt gcataaccgc tgcaagagca cctgtctctt cgtggcgaac ttgtaagaaa
     2221 cggatatctt tgtcttcagc caaagcgtcc atcaatgagc tgagtgttcc tgatgggata
     2281 ccgtagattg tatctacgcc ccatgttttc aatacgttaa gcattgctgc agatgcagta
     2341 attttccctt gagtcataat gataactctc cttcaatttt tttaaacttg gagaatacga
     2401 ttacatagaa ttggaaacgt tctccaaatt tttactattc cactgtatca tatttatgct
     2461 gacttttcta aaaatctgct caaaactctc tattctctat tctaatacag ttttgaaagt
     2521 tctgtcattt ctgttttata acaaagaaat ctagtcatta cttttagtct attttactaa
     2581 aatttaacag aagggaactg gtcagaacag atacagaact aaaggccatg gctagacctg
     2641 ccaattctgg gttgagagcc agtccaacac ctgaaaagac tcctgctgca atcggaattc
     2701 cgacaacatt gtagataaaa gcccagaaaa gattgagtag aattcgatga aaggttttct
     2761 tactcatatc aaaggcacga accactccta aaagattatt ggttgtcaac accaaatctg
     2821 ctgactcgat ggcgatatct gttccagctc ccatagcaat ccccacatct gctacactaa
     2881 gggcaggagc gtcattgata ccgtccccaa caaaggctac tttccctgac tgttgcagtt
     2941 tatggatttc atgggctttt tcttctggca agacgcctgc aatgacctct tcaattccga
     3001 tttgatctgc aatagcacgc gccacaccag cattgtctcc tgtcagcatg actgttcgga
     3061 gaccacgttt ttttagctga ctgatggcta gcttagcatt ttccttagga atatcttgca
     3121 aagcaagcaa gcctttgatt tcattgtcaa cagctaagaa cacaactgtc ttagcttctt
     3181 tttctagttc ttctagttta tcttgataag tattagaaat atccatgcca tccagcattt
     3241 tagcatttcc aagtaaaact tgttttccat tgattcgccc tgaaacacct ttcccgtgca
     3301 aggactgaaa attttcaaca gtttgaaact caagtccagc ttcactcgct cgcttaacga
     3361 tagcctcagc cagtgggtgt tgagaagcat cttccaagga ggctgccaac ccaaacactt
     3421 ctacttcgtc gccgatgaca tctgttacca caggtttccc ttccgtcaaa gtcccggtct
     3481 tatcaaagac aagggtttga actttctgga tttcctgtaa gacagttcca tttttgagga
     3541 gaacccccat cttggcacta cgtcctgtcc ccaccataag ggctgtcggt gttgcaagtc
     3601 ccaaggcaca aggacaggcg ataatcaaaa ccgccactcc gtagagaaga gaggacacaa
     3661 agctagctcc aagcacaacc acactatccc tgagcaagac gaaccaaacc caaaaggtca
     3721 tgattcctaa aatgacaact actgggacaa aaatccctga aatcttatcc gtcaagtcct
     3781 gaatcggcgc acgacttgtc tgagctttct tcacaaaatc cacaatctga gccaaaacag
     3841 tctctgagcc aactttttct gctctaaaga caagcgttcc actatgattg atggttgagc
     3901 caatgacagt atctccaact gtcttgtcca caggcagact ctcacctgtc accatggatt
     3961 cgtcaatact agagacacct tctactacga caccatcaac agcaatcttt tcaccgggac
     4021 gcactcgaat caggtcgcct accttgactt gttccaaagg aacttggaca taactatcat
     4081 cactcaagac ttctgcggtt ttagcttgca agtccagtaa tttctccaca gcttgggacg
     4141 tattttttct cattttttcc tcaaaaactg ctcccaaaag aacgaaaaag aggataaatc
     4201 cagcactttc gaagtaaaca gggagaccag caaagagagc aactaggcta tagaaataag
     4261 ccactagagt tcccagcgca accaaggtat ccatgttggc attgtgcttt ttaaaactgg
     4321 cccaagcact ctggatatat ggcttacctg caactaacat aataggcgtt gttgctagaa
     4381 aggttcccca atgcatgact tgatgactaa tgctacctgt caacatccca atcatgagaa
     4441 tcacaagagg cacagtaaag atactagtaa tccaaaaacg ttgcaggaga gatagagatt
     4501 ttcgagtctt ctcaacgact gtatagcttc ccttttgcat cttcatgcca caagaaaatt
     4561 catgtcgccc taattcttga ggcgtaaaac gaatgacttt ctcctcatct acgccgattg
     4621 gttccaagat accttcttct tcaaacagaa tttccttata acagtttgaa ggagtagcac
     4681 gatgaaaggt aatctcagct ggaattccct tttgaagctg gatatgggct ggatgatagc
     4741 ctttttcagc tcggatacgg attttttgaa tgccattttc taagcttgct ttcacaattt
     4801 ctgtcatagt ctccacctac tctacaatca tcttgccgtg catcatgttc ataccacaag
     4861 caaagccaaa ctctccagcc tgttcaggcg tgatttccac tacatactct tcccccattg
     4921 gcaggttcgc atgtacacca aaatctggaa aaacaatttg atccagacat ggtgaaggat
     4981 ccttgcggtc aaagacaatg cgtgctggca ctgatttctt gaggacaatc aactcaggag
     5041 tatagcctcc catgacttcc actcgaatct cttggtatcc gtttttttgc tgggcttttt
     5101 gtccagattt ttcaggcttt ttgaaaaacc aaaacaagat aaacgcgata agggcaatac
     5161 aaataatggt tacaatacta tttaacatga cgtctccttt acatacaatt acatcttact
     5221 tctgttacag cacttgattt cttctctgaa atcacagctt ccaagtcttc caagtcagtc
     5281 tgagtaaatt cacattctac aatcaagtca gccaacaaat tcctaatcct acgggaacaa
     5341 accttgtctt tgatatcttg gacaagtaaa tcccgacttt ggtctagagt taaaagggct
     5401 gaataaacaa aggacttgcc ttcttttttc cgagtcaaac actctttatc aaccagacga
     5461 gccaaaagtg tctgaaccgt ggacttggac cagtcaaacc gctctgccaa aaccctaatc
     5521 aaatctgtac tggtctgctc cccctgcatc caaataatct tcatgacctg ccattctgca
     5581 tctgaaatct gcattaccat acctccaaaa tctacatttg tcaattacac tcatcagtat
     5641 actcttaaaa tctacatttg tcaattatag aaataatatt ttcttcgaaa aatagaattt
     5701 taatcatttg aaaaacgatt tgcagtcaaa tattactata taaacaataa aaatatgcta
     5761 tactaaagaa aaaagaaaac aaccactagg ggtgcgtaaa gctgagatta acgactgtta
     5821 gatccctctg actcaatcta ggtaatgcta gctgatggaa gtggaaatga taatggggac
     5881 tagcagtctt ctattgcctt tctaaaacag actagcttgt tcttaagaat acaaacttca
     5941 gttggttggg aggttttaga tgacttattt acccgttgct ttgaccattg cagggactga
     6001 ccctagtggt ggtgctggca ttatggcaga tttaaagtca ttccaagcga gagatgtcta
     6061 tggaatggct gttgtaacca gtcttgtcgc tcaaaatacc agaggtgttc agctaatcga
     6121 gcacgtttct cctcaaatgt tgaaagccca attggagagt gtcttttctg atattccacc
     6181 tcaggctgta aaaactggaa tgttggctac tactgaaatc atggaaatca tccaacccta
     6241 tcttaaaaaa ctggattgtc cctatgtcct tgatcctgtt atggttgcta caagtggaga
     6301 tgccttgatt gactcaaatg ctagagacta tctcaaaaca aacttactac ctctagcaac
     6361 tattattacg ccaaatcttc ctgaagcaga agagattgtt ggtttttcaa tccatgaccc
     6421 cgaagacatg cagcgtgctg gtcgcctgat tttaaaagaa tttggtcctc agtctgtggt
     6481 tatcaaaggc ggacatctca aaggtggtgc taaagatttc ctctttacca agaatgaaca
     6541 atttgtctgg gaaagcccac gaattcaaac ctgtcacacc catggtactg gatgtacctt
     6601 tgctgcagtg attactgctg aactagccaa gggcaagagt ctttaccagg cagttgataa
     6661 ggccaaggcc tttatcacaa aagctattca agatgcccct caactcggtc atggttctgg
     6721 tccagtcaac catacaactt ttaaagatta agaaaaaaaa ctctctagtt cccactttaa
     6781 gggaattaga gagtttttat actcttcgaa aatctcttca aactacgtca gcttccatct
     6841 gcagcctcaa aacactgttt tgagctgact tcgtcagtct tatctaaaac ctcaaggcag
     6901 tactttgagc aacctgcgac tagctttcta gtttactctt tgattttcat tgagtattaa
     6961 ttaggaaaga atgttatgca acttttttaa aaaggcttgc gtttttgcct caatatcttc
     7021 tgcttgcatc aaatcacgta caacagctac accagctatg ccagtgccca taagctgatc
     7081 aatattctcc gaagtcaagc ctccaatagc aactactgga atggcaaccg tttggcaaat
     7141 tgttttcaag gtcgatatca gagtaatggg cgcattttcc ttggtggtgg ttgggaaaat
     7201 ggctcctgta cccaagtaat ctgcacctga tttctccgct tccagagctc ttttaaccgt
     7261 tttagcggtg acaccgagga ttttttcagg acccaagact ttgcgagcta ccgaaactgg
     7321 taattcatca tctccgatat gcagacctgc tgcatcaacc gcaagacaaa catccaaccg
     7381 atcatcgatt atcaagggta cctgataagc atctgttatt tccttgactt gttttgccag
     7441 ttgataatat tgattggttg tgagattttt ttctcgcaat tggactatgg taacccctga
     7501 acggcaggcc gtctcaactt ttgcaagaaa gctttccacg gaatcttgat agcgattggt
     7561 taccagatat agtctaagtg cttctctatt cataaacctc tcctttgatg gtatctagcc
     7621 aattttcatc tcttcttagg agcgaaagct gattgagtac ttggtaacga aattcttcca
     7681 atcccattcc ttgaacaact attttctcag cagcgatatt gagataagag actgctaagc
     7741 aagaagcttc aaaaccagtc tttccttggc tgagaaaaac agctgttaag gctccaacca
     7801 agtctcctgt ccctgttatc cagtctaatt cagtacagcc atttcccagt acagcgacct
     7861 gatttttcga aacgacgagg tccttgggac ctgtgactaa gaaagacata ccaggatagg
     7921 tctgacacca gtctttcaag acttgaagca aatcctccgt ttcttgatct ttagcactcg
     7981 catcgacccc aacgccgtgg tgctttaatc caacaagact tcgaatttct gacatgtttc
     8041 ctttaaggac cgtaggtcta tagtctaaaa ggtctttaac taagctctta cgaatggatg
     8101 aagtcgttac gccaaccgca tctactacca tcgggagaga agattggttt gcatacgaag
     8161 ctgccatgcg gattgctttt tccttctcag ctgacaaatg ccccaaattg atgaagagag
     8221 cctgactttg cttagtaaaa tcaagaactt cacgggaatc atctgccatg acaggtttgc
     8281 atcccagagc caaaatccca tttgccagca tctcacaaga aatctcattg gtaatgcagt
     8341 gaatgaggga actagagcct ataggaaagg gatttgtaaa ttcctgcatc agtctatcct
     8401 ttcactaaag aaatatccct gcactttttt aaagaattcc tgcttgatta aaaatcgaaa
     8461 ggcaataaag gaaatcgctg taccaatcaa ggttgctccg aaaaatcgag gcgtgtagat
     8521 aaaccagcta agcttagcag ctgatcctgt aaagagtacc ataacaggat aggaaacaat
     8581 ggaaccaata atacctgttc ccaaaatctc tcctagagca gaatagtgaa attttcgacc
     8641 gtacttataa aagagacctg ctagaagggc tccaaaagtc gctcctgtga gagctaaagg
     8701 cggaatccct tgagtcgtca tacggataaa ggctgtgact gtagccatag ccaaggcata
     8761 aacaggtccc atcatgattc ctgctagaat attgactaca ctggacatcg gtgccattcc
     8821 ctcaattcga aagataggtg taaggactac atcaagggca atcatcatag ataaaatggt
     8881 taatttgtga acttgtaatt ggtgctttct catgcttcta ttcttctcct ttttctaaag
     8941 actgtaaatc gctcttccat gtctggtgtt ggtaggccat ttcccaaaac ttggcttcca
     9001 tatgaacact gatgtggaag gcatctagca ttttttgctt gtctgtctcg tcactttctc
     9061 gatagagctg attgaccagt gctccctcct ctctgatctg ttgctctaac tcatccgtaa
     9121 tataagtttc aatccattgt tgatagagag gatttggtga tggtttaaga ttaagtgatt
     9181 tgcctatatc atggtataac caaggacaag gaagcaagct tgcaaaagcg atggctaagt
     9241 tcggttctgc aaattgccta taaatatgag aaatgtaatg ataacaggtt ggagcgattg
     9301 gatgttgctc catttcctgg tcgctgattt ccaattcctt gaaaaattgt tggcgaataa
     9361 ataactcacc ctccactaaa ccctgagcat tttgtttcaa gagtcttttc atctcttggt
     9421 ttgaagtctt atcagccaaa agatgataga tttctgagaa agccttcaga tagtaggcat
     9481 cctgaatcag gtaatagcgg aaaatggcag gttctaaatt cccctcttgt aattgtaaaa
     9541 taaagggatg atgaaaggaa gcctgccaag ctttcttgga taattccatc gcaatatctg
     9601 taaattccat aataactcct ttataaaaat agactggttt gaagcaataa aaagaaaagc
     9661 aggtagatta attttgtttt tttaggaata taaaaagtcc gatagctatt cttcaactgt
     9721 gcatgttcgt catatccgtg agcagataga gctctcaggt aaagatggcg ccacctaaag
     9781 actgtcatca gaaccttact gtaaatcaag ggcgaccaaa aatgtagttc ttgaccacgt
     9841 aataggcaag cttctttgag ggacttgatt tcttgctgaa tgagaggaaa agaattgaat
     9901 accacaatca aggcatagga ccaagagcgt gatagcccct tttgagccaa gtacaagaga
     9961 agctctttta gtgaaacaga ggaaacaaag acaaggccga tacaaactgt cacaaaggcc
    10021 ctcgttccaa gcatgactgc ctgtgaagca tctccgtgta actgaactgc ccagtagttg
    10081 gcaaaagatg gtaaaatggc aagtatgatc atccaagcta acattttaaa tcgacggtaa
    10141 tagagcataa agagaataca aaatgcgact accgaaagag tcagagcaat cgaaggaatg
    10201 aaagatgttt ccaaggataa aatcagcaag aagagactga taatcggtgt ctgggttgct
    10261 actttgacca tactatctca cctccccttg ggtattgcta ctctgagatg taagtggttt
    10321 ggtaatggtc acttctttca catgccgaag accctgacta gtcatctcaa tccaataatc
    10381 aaccacagaa atcaaagggt ctaaacgatg actaatgagc agaaaacttc ttccttgatt
    10441 cctctcctcc acaatccact tgcaaaaata atggcaggct ctatcatcca aacctgcaaa
    10501 aggttcatct agcaagatca cggaagcctt actggtcaag atggtcagga gctgaagaat
    10561 tttttgctga ccaccactta attgataggg actcttatcg actgcctgct ccaaatcaaa
    10621 atatcgtaaa gcttgaaaaa tccgctgatt tctttcagaa tcaggtccat ctaattgaag
    10681 ctcctctcgc agactgactc ggataaactg cttctcagct tcctgaacaa caccagtcag
    10741 atcacgatac aaactctttt tctttttcag gaccgaaccc ttccaagtaa tgctcccctt
    10801 atacttttga aattgaagaa tagaccgaaa gagggttgat ttcccgacac cattgtcacc
    10861 caggatacag gaaatccctt gatagaatgt gaaatcagca attgaaaaga gggggcgatt
    10921 accaagctca ccagtcacac ggttcatatg gaatagttcc gggctagaag caacttcctt
    10981 tgaagcaacc tgtgtcatct cataggaagg gatttgaaac acttccctta gttttccgtc
    11041 tcttagctcc accatatggt cgatataggc tttatagtca gataaatcat ggtcgcacaa
    11101 aataactgtc ttcccatcat agaccaactc ttttagaatc tccaatatct cgattctgct
    11161 cttgcggtca atggaagcga agggctcatc caagagatag accctaggat tcatggcaaa
    11221 gaggacagcc agcgctgctt tttgcttttc cccacctgat aagtgatgga tgagacggtg
    11281 caagatgtcc ttgcaacgac attgctggac aacctctgct attttagaat caatttcctg
    11341 aaggtgatag ccgatatttt ccatggtaaa aaccaactcc tcaaacaagc tctccatggt
    11401 aaattgatga ttaggatttt gcaagagaat accaaccgtc tggacacgtt cgacgataga
    11461 aagctgactg acctcgctcc catctatcag gacttgaccg ctatagggaa gagaactaac
    11521 ttgggcaatc atttgaaaga ggctggattt tccagaccca ctactcccaa ctaacaaggt
    11581 aaaggcttgc gcatgaaaag taaaatcaaa cggctcagag aagattgggg actgaatcgc
    11641 tcgtagttcc agacccatct atgcttttcc tccagttgca aactgatgat agagtttgac
    11701 aatggcacga accaagatgg tacagaagaa ataaacagaa ataaaacgta ccacaagcaa
    11761 ggaaaggaca aacggaaggg aaaaggcgta gtaacctaac ttaatgtatt catagacaaa
    11821 gctaacaagc gtaatcccaa tactattagc agttagagag agccaacttt catagcgatt
    11881 cttagttacg ataaaaccaa attcacttcc caaaccttga acaaagccag acaaaagagc
    11941 tcctagacca aattggctac cataaaggac ttcagcaagc gcagctagca cttctccaat
    12001 cgttgcactt ccgactctcg gaacaaagat ggcagcaatg ggcgcagcca tacaccagag
    12061 accgaagagg atttcattgg caaaggcctg caaaccaaga ggtgttaaga gtagactgag
    12121 aatattatac acatatcctg aaccaacgaa aaccccacca aaaaagatag acaagaaagc
    12181 aagcaagata acatctttta actgccattt tttcaacata aaaaactcct ttttttaaag
    12241 aaaagtgagg cactcaagaa gaccgaccta aatactttgt atagcagact gaatttagaa
    12301 cagtacacaa gaacactaaa atatttctag aaattaattt gaattttcta attgatttgt
    12361 tcgcatctta tttcaatcta ctatatcatc ttcatccagt ttcgtaaaag aaaaaactct
    12421 aattacagat acaaattaga gttcagctta caagattaga cagttctttt cgacatacga
    12481 aaaaaacatt tcacatttcc cttcgccagt cttaactgta tcaggttcaa tgggtatcat
    12541 ctcagcctaa agcaccccaa atgtctttat tatttaatta tgtgattatt ataacacaca
    12601 ttttatacta gttcaagaaa ttgaactgga aatacagcct tgcactcaca aagacagcag
    12661 atctttcttt tgcaaaaaac aaatgacctg tttgatgaat tagccattca agctgaatct
    12721 ggacatagct ttttaaaaaa ggaaaatcct acttacttag aatccaagga tagatatcta
    12781 ttgttcactc atttcccgaa cagttttttc tatatttttt gcatacgata ttgccgaaat
    12841 gattgaaacg ccatccatat tggtctttat aatgtcttta atatgtttcg tctgtatccc
    12901 accaattgca actaaaggca tttgtggcaa tagttttctc atcaattcaa gaccttcata
    12961 acctatagta ccaccagcat catcctttga ctgggtacca aatacaggcc caacacctac
    13021 ataatctaca tattcaactt ttgattgttg aaattcttct tcgtttctta tagaaagacc
    13081 aattatttta tctggcatca attttctaat ttcatcaaca ccaatatcat cttgacctac
    13141 atgtacgcca tcggcgtcaa tttccattgc taaatctata tcgtcattaa cgataaatgg
    13201 aacattgtat tttttacaaa gttctttaat ttggatagct agctcaagtt tttctaagcc
    13261 ttctaaagca ccctcacctt tttctcgaaa ttgaaataag gttataccac cttttaaggc
    13321 ttcctcaacg actgtatata gattttttcc ttggcaagta gtcgttccac aaataaaata
    13381 tagttttagt aattctttat gaaacatctt acttcactct tttgaattcc tttacatctt
    13441 catctgtaat ctcgtataag gcatttataa attcaacttt aaatgtccca ggaagatgtc
    13501 catttggacg tttttctgct atttctccag cgatattgta aaccaacact gctgttttta
    13561 atgatttcaa ttcttgacct ttttctagtc cgataaagct tgctactaca gctcctaata
    13621 agcatcctgt cccaatgact ttcggcatca tagcactacc attatgaatc attaccactt
    13681 ctccattaac agcaatggca tccacttcac ctgttactac tattggaata ttgaacttct
    13741 catttgctgc tagagcaatt tcgtcaatat tatctacgcc cgcactatct actcctttag
    13801 atgccacatc tattcctact aaagaggcaa tctcgccagc atttcctcta atcgctgcta
    13861 gtttataatt gttgattaga tcatctgcta ctttttttct atattctcct gctccacagg
    13921 ctacaggatc taaaactgct gggacattat atttctctgc aattttcaga gcagcttggt
    13981 ataatttcca attttcatct gtcaatgttc ctatgtttat taataaacca ccagcatact
    14041 ttaacaaatc ctctaaatct gctggaaact cactcatggc tggtgaggcg cccagtgcta
    14101 ctaatccatt tgctgtgaaa ttttttacta catcattggt tatacaaatg accaatggtg
    14161 ctttttcttt taataatttt aaacttgtca tattgaaatc cttccttttc actttatacg
    14221 atctactaat ttcgatttat ctttagttga gaattttttt catttacatt gaatgattta
    14281 tactcaatga aaatcaaaga gcaaactagg aggctaaccg caggttgctc aaaacactgt
    14341 tttgaggttg tggatagaac tgacgtggtt tgaagagatt ttcgaagagt cttacctcat
    14401 caaatttgta aatatcatga gccttctcta gacatcgtaa ccaatatcaa aaaaagctaa
    14461 ttctaaagcg actgcttgat tccagcgttg ctgaagttct gtcaaatctt ctcgattttt
    14521 accgacacga ttgagttcgt caaccagaaa ttgaacccac tctgcaaaga aaggacctct
    14581 gtggagattg atccattccg aatgaatata gacttcaggt aaagccaaat ctttagaacc
    14641 ccagtctaaa tagagacctt ctgcaatgac cagcatgacc aaaagatggg catagtctga
    14701 tgaagccacc gccgaataca ttagatcctg aaaggctttt gttacagggt gcaaagtcac
    14761 ttctagatag tcattctctg ctacttttaa ctctttaaaa gccttttgga aataaccatc
    14821 ttcatctgct tcaagaaagc ctagttgctt ggcaaaacga agcttggatt caagtttatc
    14881 tgcgtgagct acgcaggcac ccagcatgga taagaaggca tcaaagaagt gataatcttg
    14941 aatcagatag tcctttaaga ccttattctc aattgtcccc gcaaaaagtt ccttaacaaa
    15001 acgatgattg attgcagcct gccaatcctt ctgactgctt tttaataatt ctccaacagt
    15061 caaacctggc tgaaatgcat agtcttgtgt ttccatattt acttctcctc tctttacttg
    15121 ttagtaatta ataaaacacc aagaaatatc aagcaaaatc gtaattccac ttgatccttt
    15181 taaagcacat cgagagcatt tgcagagagc taactaaaca agcctatcca gtttatataa
    15241 acaaaaaact ccaattacaa tcaagaatta gagttgactt acaagattag accgttcatt
    15301 tcaccatacg aaaaaactgt tcacatttcc cttcgccagt cttaactgta tcaggttcaa
    15361 tgggtattat ctcagcctaa agcaccccaa atgtctctat tatttaacta ctgaaccagt
    15421 atagcaaaaa atgaaagccc tagcaagata tttgaccgaa aaatatcttt atatataata
    15481 tattgaaact agaatagtac acctctactt ataaaacatt gttagaaatc gatttgactg
    15541 tcctgattga tttgtcctat tcttatttca ttttactata gttttcgata gcaatttatt
    15601 cttccaatac acgaagaaaa acctccacat tcagtggagg caatctgttt tatcaataca
    15661 attttaagtc acgagggtca actgggaagg ttgggttgta tggattgtga cggagcttga
    15721 agtgtttgac atcttcaatg gtctgagttc cagacaattg cataactgtc ttcaattccg
    15781 cattcaagtg ttcaaagact tgacgcacac cgacactacc accgagagcc aagccataga
    15841 tgacagggcg tccaatagca accaagtctg ctcctgatgc caaggcttta aagacgtgtt
    15901 gaccacgacg aacaccagag tcaaagacaa tcggcacacg tctatcaact gcttctgcca
    15961 cttcttgaag cgagtcaaag gcagctggtc caccgtcgat ttgacgacca ccgtggttgg
    16021 ttacccagat accagaagct cctgcagcaa gcgaacgttc aacgtcctca cggcattgtg
    16081 gtcccttgac atacacagga agaccagagt attcagcgat aaattctaca tcgcgtggag
    16141 acaagcgttg tttagctgat ttgtaaacaa agtccattga tttaccagca ccttctggca
    16201 ggtattcttc aacaatcggc atgccaactg ggaagacaaa accattacgc ttatccactt
    16261 cacgattccc ccctacagta gcatctgccg tcaagacaat cgctttataa ccttcagcct
    16321 tcacacggtc catgatgtgg cggttgatac cgtcatcctt actaaagtaa aattgaaacc
    16381 aatgaggtgt cccttggagg gcttcagaaa tctctggaag gtcaacagta gagtaagaac
    16441 tggttgtata aagagaacca aactcatgca caccacgcgc agtcgccact tccccctgtt
    16501 catttgccaa tttatgagcc gcaacaggtg ccataatgat tggagaagat agtttttcac
    16561 ctgcaaattc aatctctgta cttggatttt ctacattgca aagtgtatga ggaacgatga
    16621 gcttgtggtt aaaggcacgg atattctctc ttaaagtgaa agtatcttcc gccccactag
    16681 cgatatagcc aaatgctgct ttaggaataa cttgttgcgc cattggctcc aaatcatagg
    16741 tattgatgaa gtctacatga ccttctgcat tgcttgtttt gtatgacata aactgtcctc
    16801 ctcgattaag taagcgtttg ctttttacta tacaactata ataactcttt tttcaatcat
    16861 tttcaagagt tttgcttaaa aaccatctta ttttttcata caatatacta gccctacttt
    16921 ccttaaactc taaaccttag tctatattaa gtgaatcgtt gagatttttt gctgccaggc
    16981 atttgaacta cttt
//
LOCUS       DAVFER010000046        16608 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1105170250
            SAMEA2167659-rid19724873.denovo.046, whole genome shotgun sequence.
ACCESSION   DAVFER010000046 DAVFER010000000
VERSION     DAVFER010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2167659
            Sequence Read Archive: ERR388902
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 16608)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16608)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928716.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928716.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 04:07:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,118
            CDSs (total)                      :: 2,073
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 120
            CDSs (without protein)            :: 120
            Pseudo Genes (ambiguous residues) :: 0 of 120
            Pseudo Genes (frameshifted)       :: 67 of 120
            Pseudo Genes (incomplete)         :: 47 of 120
            Pseudo Genes (internal stop)      :: 34 of 120
            Pseudo Genes (multiple problems)  :: 23 of 120
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16608
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2167659-rid19724873.denovo.046"
                     /strain="1105170250"
                     /db_xref="taxon:1313"
     gene            complement(171..1253)
                     /locus_tag="VU534_001680"
     CDS             complement(171..1253)
                     /locus_tag="VU534_001680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEU1514235.1"
                     /translation="MKTKLPTEWQELSDQLGFQEFTPIQTQLFEPLLAGENLLGVSQT
                     GTGKTLAYLLPSLLRLQKKKAQQLLILAPNTELAGQIFDVCKTWAEAIGLTAQLFLSG
                     SSQKRQIERLKKGPEILIGTPGRIFELIKLKKIKMMNVETIILDEFDQLLDDSQIHFV
                     EKITHYAPRDHQLVYMSATTKFDQEKIVPNTRTIDLSDQKLDNIQHFYMQVDQRHRVD
                     MLRKLAHVEDFRGLVFFNSLSDLGNAEEKLQYRDILAVSLASDVNVKFRKIILEKFKD
                     NQLTLLLATDLLARGIDIDSLECVVNFDIPRDSETYTHRAGRTGRMGKEGYVITLVTH
                     PEEIKKLKKFASIREIVLKNQELYIK"
     gene            complement(1250..2227)
                     /locus_tag="VU534_001681"
     CDS             complement(1250..2227)
                     /locus_tag="VU534_001681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEU1514236.1"
                     /translation="MLKLGVIGTGAISHHFIEAAHTSGEYQLVAIYSRKLETAATFAS
                     RYQNIQLFDQLEVFFKSSFDLVYIASPNSLHFAQAKAALSAGKHVILEKPAVSQPQEW
                     FDLIQTAEKNNCFIFEAARNYHEKAFTTIKNFLADKQVLGADFNYAKYSSKMPDLLAG
                     QTPNVFSDRFAGGALMDLGIYPLYAAVRLFGKANDATYHAQQLDNSIDLNGDGILFYP
                     DYQVHIKAGKNITSNLPCEIYTTDGTLTLNTIEHIRSAIFTDHQGNQVQLPIQQAPHT
                     MTEEVAAFAHMIQQPDLNLYQTWLYDAGSVHELLYTMRQTAGIRFEAEK"
     gene            2442..2819
                     /locus_tag="VU534_001682"
                     /pseudo
     CDS             2442..2819
                     /locus_tag="VU534_001682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001833802.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family transposase"
     gene            3054..4445
                     /locus_tag="VU534_001683"
     CDS             3054..4445
                     /locus_tag="VU534_001683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013193417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HEU1514237.1"
                     /translation="MNKSRLGRGRHGKTRHVLLALIGILAISICLLGGFIAFKIYQQK
                     SFEQKIESLKKEKDDQLSEGNQKEHFRQGQAEVIAYYPLQGEKVISSVRELINQDVKD
                     KLESKDNLVFYYTEQEESGLKGVVNRNVTKQIYDLVAFKIEETEKTSLGKVHLTEDGQ
                     PFTLDQLFSDASKAKEQLIKELTSFIEDKKIEQDQSEQIVKNFSDQDLSAWNFDYKDS
                     QIILYPSPVVENLEEIALPVSAFFDVIQSSYLLEKDAALYQSYFDKKHQKVVALTFDD
                     GPNPATTPQVLETLAKYDIKATFFVLGKNVSGNEDLVKRIKSEGHVVGNHSWSHPILS
                     QLSLDEAKKQITDTEDVLTKVLGSSSKLMRPPYGAITDDIRNSLDLSFIMWDVDSLDW
                     KSKNEASILTEIQYQVANGSIVLMHDIHSPTVNALPRVIEYLKNQGYTFVTIPEMLNT
                     RLKAHELYYSRDE"
     gene            4559..5401
                     /locus_tag="VU534_001684"
     CDS             4559..5401
                     /locus_tag="VU534_001684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HEU1514238.1"
                     /translation="MNTYQLNNGVEIPVLGFGTFKAKDGEEAYRAVLEALKAGYRHID
                     TAAIYQNEESVGQAIKDSGVPREEMFVTTKLWNSQQTYEQTRQALEKSIEKLGLDYLD
                     LYLIHWPNPKPLRENDAWKTRNAEVWRAMEDLYQEGKIRAIGVSNFLPHHLDALLETA
                     TIVPAVNQVRLAPGVYQDQVVAYCREKGILLEAWGPFGQGELFDSKQVQEIAANHGKS
                     VAQIALAWSLAEGFLPLPKSVTTSRIQANLDCFGIELSHEERETLKTIAVQSGAPRVD
                     DVDF"
     gene            5674..6434
                     /locus_tag="VU534_001685"
                     /pseudo
     CDS             5674..6434
                     /locus_tag="VU534_001685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397459.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
     gene            6805..7722
                     /gene="glyQ"
                     /locus_tag="VU534_001686"
     CDS             6805..7722
                     /gene="glyQ"
                     /locus_tag="VU534_001686"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018163989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HEU1514239.1"
                     /translation="MSKKLTFQEIILTLQQFWNDQDCMLMQAYDNEKGAGTMSPYTFL
                     RAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPSNIQELYLESLEK
                     LGINPLEHDIRFVEDNWENPSTGSAGLGWEVWLDGMEITQFTYFQQVGGLATGPVTAE
                     VTYGLERLASYIQEVDSVYDIEWADGVKYGEIFIQPEYEHSKYSFEISDQEMLLENFD
                     KFEKEAGRALEEGLVHPAYDYVLKCSHTFNLLDARGAVSVTERAGYIARIRNLARVVA
                     KTFVAERKRLGYPLLDEETRAKLLAEDAE"
     gene            7934..9970
                     /locus_tag="VU534_001687"
     CDS             7934..9970
                     /locus_tag="VU534_001687"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HEU1514240.1"
                     /translation="MTKNLLVELGLEELPAYVVTPSEKQLGEKMAAFLKGKRLSFEAI
                     QTFSTPRRLAVRVTGLADKQSDLTEDFKGPAKKIALDSDGNFTKAAQGFVRGKGLTVE
                     DIEFREIKGEEYVYVTKEEIGQAVEAIVPGIVDVLKSLTFPVSMHWAGNSFEYIRPVH
                     TLTVLLDEQEFDLDFLDIKGSRVSRGHRFLGQETKIQSALSYEEDLRKQFVIADPCER
                     EQMIVDQIKEIEAKHGVRIEIDADLLNEVLNLVEYPTAFMGSFDAKYLEVPEEVLVTS
                     MKEHQRYFVVRDQDGKLLPNFISVRNGNAERLKNVIKGNEKVLVARLEDGEFFWREDQ
                     KLVISDLVEKLNNVTFHEKIGSLREHMIRTGQITVLLAEKASLSVDETVDLARAAAIY
                     KFDLLTGMVGEFDELQGIMGEKYTLLAGETPAVAAAIREHYMPTSAEGELPESKVGAV
                     LAIADKLDTILSFFSVGLIPSGSNDPYALRRATQGVVRILDAFGWHIAMDELIDSLYA
                     LKFDSLTYENKAEVMDFIKARVDKMMGSTPKDIKEAVLAGSNFVVADMLEAASALVEV
                     SKEEDFKPSVESLSRAFNLAEKAEGVATVDSALFENDQEKALAEAVETLILSGPASQQ
                     LKQLFALSPVIDAFFENTMVMAEDQAVRQNRLAILSQLTKKVAKFACFNQINTK"
     gene            10012..10269
                     /locus_tag="VU534_001688"
     CDS             10012..10269
                     /locus_tag="VU534_001688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002901318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 family protein"
                     /protein_id="HEU1514241.1"
                     /translation="MDPKKIARINELAKKKKTEGLTPEEKVEQAKLREEYIEGYRRAV
                     RHHIEGIKIVDEEGNDVTPEKLRQVQREKGLHGRSLDDPNS"
     gene            complement(10492..11736)
                     /locus_tag="VU534_001689"
     CDS             complement(10492..11736)
                     /locus_tag="VU534_001689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000673688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEU1514242.1"
                     /translation="MKFVGLVGSNYDQSYNRKLLEFIRRYFKLKFELEVLEIDEVPMF
                     NQDEKWDESFQLRYLYNKITRADGVIIATPEHNHTISASLKSVLEWLSYEVHPFENKP
                     VMIVGASYYDQGTSRAQVHLRKILDAPGVNAYTLPGNEFLLGKAKEAFDNNGNITNEG
                     TVKFLETCLDNFVKYVGVVSKLKKPKPIESEDLDCGKPIATTITEVDPDDPEWVEKVA
                     AFTGAVSGDTYVKLDHGILTVNQIDMFLKAMPFELTYADDNNQFLYYNNAHQDPDTMF
                     AKRVPPQSGSRMSTVHGSLPPARMKNVEWVIGTLRNGNQEYVRTIVPGSPAGVINTHN
                     YQAMYYPDGSYAGINEIVFNFQPWLDWYLKETGQRLVGGSGPFAPAAGGHGDADATSG
                     ASDSGDAGGHGGDADATAGASY"
     gene            complement(11755..12360)
                     /locus_tag="VU534_001690"
     CDS             complement(11755..12360)
                     /locus_tag="VU534_001690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEU1514243.1"
                     /translation="MLKLIAIVGTNSKRSTNRQLLQYMQKHFTDKAEIELVEIKAIPV
                     FNKPADKQVPAEILEIAAKIEEADGVIIGTPEYDHSIPAVLMSALAWLSYGIYPLLNK
                     PIMITGASYGTLGSSRAQLQLRQILNAPEIKANVLPDEFLLSHSLQAFNPSGDLVDLD
                     VIKKLDAIFDDFRIFVKITEKLRNAQELLRKDAEDFDWENL"
     gene            complement(12420..13343)
                     /locus_tag="VU534_001691"
     CDS             complement(12420..13343)
                     /locus_tag="VU534_001691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000175414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HEU1514244.1"
                     /translation="MTLRSHSERLMGTTITISLVDEQADIFLQKSFDLLKELEYRFNA
                     NSQESELMEINYQAGIAPVTVHPDLFELISLGLEHSLALSSHLNISIGPLIQTWRIGF
                     SDAKVAQPQEIESVLPLINPHGIELDSSTSTVFLKQKGMKIDLGCLAKGYSADKVAQF
                     LRKEGVTSALINLGGNILTIGKNQARGDNPWQIGIQDPANPRGNHLMTIPVVNKSVVT
                     SGIYERHLTVDGQDYHHIFDSQTGYPVETELASLTIISDKSVDGEIWTTRLFGERPAS
                     ILWQVESLEGIEVILIDKEGHLSCSSGIPTL"
     gene            13637..15016
                     /locus_tag="VU534_001692"
     CDS             13637..15016
                     /locus_tag="VU534_001692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HEU1514245.1"
                     /translation="MSKIVVVGANHAGTACINTMLDNFGNENEIVVFDQNSNISFLGC
                     GMALWIGEQIDGAEGLFYSDKEKLEAKGAKVYMNSPVLSIDYDNKVVTAEVEGKEHKE
                     SYEKLIFATGSTPILPPIEGVEIVKGNREFKATLENVQFVKLYQNAEEVINKLSDKSQ
                     HLDRIAVVGGGYIGVELAEAFERLGKEVVLVDIVDTVLNGYYDKDFTQMMAKNLEDHN
                     IRLALGQTVKAIEGDGKVERLITDKESFDVDMVILAVGFRPNTALAGGKIELFRNGAF
                     LVDKKQETSIPDVYAVGDCATVYDNARKDTSYIALASNAVRTGIVGAYNACGHELEGI
                     GVQGSNGISIYGLHMVSTGLTLEKAKAAGYNATETGFNDLQKPEFMKHDNHEVAIKIV
                     FDKDSREILGAQMVSHDIAISMGIHMFSLAIQEHVTIDKLALTDLFFLPHFNKPYNYI
                     TMAALTAEK"
     gene            15168..16043
                     /gene="pdxS"
                     /locus_tag="VU534_001693"
     CDS             15168..16043
                     /gene="pdxS"
                     /locus_tag="VU534_001693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012054698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal 5'-phosphate synthase lyase subunit
                     PdxS"
                     /protein_id="HEU1514246.1"
                     /translation="MTENRYELNKNLAQMLKGGVIMDVQNPEQARIAEAAGAAAVMAL
                     ERIPADIRAAGGVSRMSDPKMIKEIQEAVSIPVMAKVRIGHFVEAQILEAIEIDYIDE
                     SEVLSPADDRFHVDKKEFQVPFVCGAKDLGEALRRIAEGASMIRTKGEPGTGDIVQAV
                     RHMRMMNQEIRRIQNLREDELYVAAKDLQVPVELVQYVHEHGKLPVVNFAAGGVATPA
                     DAALMMQLGAEGVFVGSGIFKSGDPVKRASAIVKAVTNFRNPQILAQISEDLGEAMVG
                     INENEIQILMAERGK"
     gene            16044..>16608
                     /gene="pdxT"
                     /locus_tag="VU534_001694"
     CDS             16044..>16608
                     /gene="pdxT"
                     /locus_tag="VU534_001694"
                     /EC_number="3.5.1.2"
                     /EC_number="4.3.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000689933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal 5'-phosphate synthase glutaminase
                     subunit PdxT"
                     /protein_id="HEU1514247.1"
                     /translation="MKIGILALQGAFAEHAKVLDQLGVESVELRNLDDFQQDQSDLSG
                     LILPGGESTTMGKLLRDQNMLLPIREAILSGLPVFGTCAGLILLAKEITSQKESHLGT
                     MDMVVERNAYGRQLGSFYTEAECKGVGKIPMTFIRGPIISSVGEGVEILATVNNQIVA
                     AQEKNMLVSSFHPELTDDVRLHQYFINM"
BASE COUNT         5036 a         3023 c         3687 g         4862 t
ORIGIN      
        1 aagatgtcat gaatcaactc caagatgtca tacaaggatt ggagaaggag gtgataaagt
       61 ccatcgttaa tcggagatgg actagaatgc tttttgaaaa cagatgagta taaaattgaa
      121 ttgcttataa aaaagctcca tacactggat gtgtatagag caatggggct ttatttgata
      181 tagagttctt ggttttttag gacaatttct cggatacttg caaacttttt aagttttttg
      241 atttcttctg gatgagtgac gagagtgata acataacctt ccttgcccat acgaccagta
      301 cggccagcac ggtgtgtgta ggtttcgcta tctctaggaa tatcaaagtt tacgacacat
      361 tctaggctat cgatatcaat tccacgagcc aaaaggtcag ttgcaagaag cagggttagt
      421 tggttatctt taaacttttc taagatgatt tttctaaatt taacattaac atcactagcg
      481 agggaaacag ccaatatatc acgatactgt agtttttcct cggcattccc aaggtctgac
      541 aggctattga agaagactag accacggaaa tcctctacat gagccagttt tcgtagcata
      601 tccactcgat gacgttggtc tacctgcatg tagaaatgct ggatattgtc caatttttga
      661 tcagagagat caatagtgcg tgtattcggc acaatctttt cttggtcaaa cttggtcgtg
      721 gcactcatgt agaccagttg gtggtcacga ggtgcgtagt gagtgatttt ttctacaaag
      781 tgaatctgag aatcatctag taattggtca aattcatcca ggatgatggt ttccacattc
      841 atcatcttga tttttttaag tttaatgagt tcaaagatac ggccaggagt tccaatcaga
      901 atttctggcc cctttttaag acgttcaatt tgtcgtttct gacttgaacc tgaaaggaag
      961 agttgagcag tcaatccgat agcttctgcc cacgttttac atacatcaaa aatctgtcca
     1021 gcaagttccg tatttggtgc tagaatcaag agttgttggg cttttttctt ttgtagtctg
     1081 agaagacttg gtaggagata cgctagggtc ttaccagttc cggtttggct cactcctagg
     1141 aggttttctc cagcaagaag gggctcaaat agttgagttt gaatgggggt gaattcttgg
     1201 aaaccgagtt ggtcactcag ttcttgccat tcagtcggta gtttggtttt catttttctg
     1261 cctcaaatct aatgccagca gtctggcgca tggtatatag tagctcatga acagagcctg
     1321 catcatacag ccaagtttgg tagagattca gatctggttg ctggatcatg tgtgcaaatg
     1381 cagcgacttc ctcagtcatc gtatgaggag cctgttggat aggaagctgg acttgatttc
     1441 cttggtggtc ggtaaaaata gctgagcgaa tatgctcaat cgtgttgaga gtcaaggttc
     1501 catctgttgt ataaatctcg caaggaagat tggaagtgat gttttttcca gccttgatgt
     1561 gaacttgata gtctgggtag aagaggatac catctccatt taggtcaatg ctattgtcaa
     1621 gctgttgagc atggtaagtc gcgtcattgg cttttccaaa aagacgaaca gcagcataga
     1681 ggggataaat ccccaaatcc atgagggctc caccagcaaa acggtctgaa aagacatttg
     1741 gtgtttgtcc agccaacaag tcaggcatct tggaagagta tttggcatag ttgaaatctg
     1801 ctcctaacac ttgcttatct gctaaaaagt ttttgatagt agtaaaggct ttctcgtggt
     1861 aattacgagc tgcttcaaag ataaaacagt tatttttttc agctgtttga atcaaatcaa
     1921 accattcttg tggttgagag acagctggct tttcgagaat aacatgttta ccagcagaca
     1981 aggcagcttt tgcctgagca aaatgtaagg agtttggact ggcgatatag actaaatcaa
     2041 aagaagattt gaagaagact tctaattgat cgaatagttg gatattctga tagcgagaag
     2101 caaaggttgc tgcagtttct agttttctag aatagattgc gaccagttgg tattctccac
     2161 tggtatgggc tgcttctatg aaatgatggc tgatagcgcc agttccgatg acacctaatt
     2221 ttagcataaa tactcctttt ccgattttaa atccttcttt cattataaca tagatagacg
     2281 ggactatcca acagagagga gaaaatttca aataagctat tagctttctt ttccgaataa
     2341 atagatagaa gcatagaatc tagcaaacct agatttaaaa atgtgctata atagaaggag
     2401 gaaaaggagg attctcagac atctaggtat cagcccaact aatgatttgt caatttatcc
     2461 gcgatatgct ggacttgcca gcaaaaaatg tgacgatttt ggagggaagt aacattcacg
     2521 tcttgccttc catgccctac tcagcgtaag atttctatac tagtatagac gtcttggcgg
     2581 agttagataa tggaatccaa gttatcatcg aaattcaggt tcatcatcag aattttttca
     2641 tcaatcgcct atggccttat ctgtgcagtc aggttaatca aaacctagaa aaaattcgcc
     2701 aacgtgaagg tgatacccac cagagctaca aacaaatcgc actagtatac gctatcgcaa
     2761 ttgtcgatag taattacttc tcagatgacc tagcttttca tagttttata gtaaaatgaa
     2821 atgagaacag gacaaatcga tcaggacagt caaatcgatt tctaacaatg ttttagaagt
     2881 ataggtctac tattctagct tcaatctact agaaattcca tagatagaaa actacataat
     2941 ctctacagat acggatgttg gagttgatgt aagatgcttt ggcttgctag aggaattgtg
     3001 gattgccaaa ttgtatcatt gaaattattg ctcaaatttg ttatgatata aatatgaata
     3061 aaagtagact aggacgtggc agacacggga aaacgagaca tgtattattg gctttgattg
     3121 gtattttagc aatttctatt tgcctattag gcggatttat tgcttttaag atctaccagc
     3181 aaaaaagttt tgagcaaaag attgaatcgc tcaaaaaaga gaaagatgat caattgagtg
     3241 agggaaatca gaaggagcat tttcgtcagg ggcaagccga agtgattgcc tattatcctc
     3301 tccaagggga gaaagtgatt tcctctgtta gggagctgat aaatcaagat gttaaggaca
     3361 agctagaaag taaggacaat cttgttttct actatacaga gcaagaagag tcaggtttaa
     3421 agggagtcgt taatcgtaat gtgaccaaac aaatctatga tttagttgct tttaagattg
     3481 aagagactga aaagaccagt ctaggaaagg ttcacttaac agaagatggg caacctttta
     3541 cacttgacca actgttttca gatgctagta aggctaagga acagctgata aaagagttga
     3601 cctccttcat agaggataaa aaaatagagc aagaccagag tgagcagatt gtaaaaaact
     3661 tctctgacca agacttgtct gcatggaatt ttgattacaa ggatagtcag attatccttt
     3721 atccaagtcc tgtggttgaa aatttagaag agatagcctt gccagtatct gctttctttg
     3781 atgttatcca atcttcgtac ttactcgaaa aagatgcggc cttgtaccaa tcttactttg
     3841 ataagaaaca tcaaaaagtt gtcgctctaa cctttgatga tggtccaaat ccagcaacga
     3901 ccccgcaggt attagagacc ctagctaaat atgatattaa agcgactttc tttgtgcttg
     3961 ggaaaaatgt ttctgggaat gaggacttgg tgaagaggat aaaatctgaa ggtcatgttg
     4021 ttggaaacca tagctggagc catccgattc tctcgcaact ctctcttgat gaagctaaaa
     4081 agcagattac tgatactgag gatgtgctaa ctaaagtgct gggttctagt tctaaactca
     4141 tgcgtccacc ttatggtgct attacagatg atattcgcaa tagcttggat ttgagcttta
     4201 tcatgtggga tgtggatagt ctggactgga agagtaaaaa tgaagcatct attttgacag
     4261 aaattcagta tcaagtagct aatggctcta tcgttttgat gcatgatatt cacagtccga
     4321 cagtcaatgc cttgccaagg gtcattgagt atttgaaaaa tcaaggttat acctttgtga
     4381 ccataccaga gatgctcaat actcgcctaa aagctcatga gctgtactat agtcgtgatg
     4441 aataagcaag aaaaaatagg tctgttagat atttgacaga cttatttttt acagaatata
     4501 gtactactta aaaaatgttt tatgctataa ttgatgaata aaatagaagg agaagcatat
     4561 gaatacctat caattaaata atggagtaga aattccagta ttgggatttg gaacttttaa
     4621 ggctaaggat ggagaagaag cctatcgtgc agtgttagaa gccttgaagg ctggttatcg
     4681 tcatattgat acggcggcga tttatcagaa tgaagaaagt gttggtcaag caatcaaaga
     4741 tagcggagtt ccacgtgaag aaatgttcgt aactaccaag ctttggaata gtcagcaaac
     4801 ctatgagcaa actcgtcaag ctttggaaaa atctatagaa aaactgggct tggattattt
     4861 ggatttgtat ttgattcatt ggccgaaccc aaaaccgctc agagaaaatg acgcatggaa
     4921 aactcgcaat gcggaagttt ggagagcgat ggaagacctc tatcaagaag ggaaaatccg
     4981 tgctatcggc gttagcaatt ttcttcccca tcatttggat gccttgcttg aaactgcaac
     5041 tatcgttcct gcggtcaatc aagttcgctt ggcgccaggt gtgtatcaag atcaagtcgt
     5101 agcttactgt cgtgaaaagg gaattttatt ggaagcttgg gggccttttg gacaaggaga
     5161 actgtttgat agcaagcaag tccaagaaat agcagcaaat cacggaaaat cggttgctca
     5221 gatagccttg gcctggagct tggcagaagg atttttacca cttccaaaat ctgtcacaac
     5281 ctctcgtatt caagctaatc ttgattgctt tggaattgaa ctgagtcatg aggagagaga
     5341 aaccttaaaa acgattgctg ttcaatcggg tgctccacga gttgatgatg tggatttcta
     5401 gaaaatcata aaaagaattg tacattattc taatttttga tataatagtc agcaggaaag
     5461 aaagtcttat ggcgttcttc aagcgagctt gggatagtgg gagccaagta gggcaaaata
     5521 aagggctggc gctttctgta gtattttcaa aaacaatgaa gtaataaatt agggtggaac
     5581 cgcgtttctg acgcccctag gttaaatcaa cctaggattg tcagatgtgg ttcttttgct
     5641 tattcagtct attgtgtgaa agaaaggaga gccgtggaca acctttatct tgtaaaagac
     5701 gatagtcaac tagctacatt tcgtgatttt gtagtaagaa atactgaaaa gttgaaagat
     5761 tatcaatctt ttttaaagaa tgaacttgca gtctgtgatt taccgcaagc tgttatttgg
     5821 tcagatttta atgctgctac acagattatt agggaaagtg ctgttccaac ctatacaaat
     5881 aatagacgag tggttatgac gcctgattta gctgtttgga aagaattgta tttgtatcag
     5941 ttgatggact acgagtgttc tgagcaaact caagcaatag aaagtcacta tcattcttta
     6001 tctgaaaatt tcctcttaca gattgtagga catgagttag ctcattggtc ggacattttt
     6061 tagatgattt tgatggttat gactcttata tctggttcga agaggggatg gttgaatata
     6121 ttagtcgcaa gtatttcttg acagaagagg aatttcaagc ggaaaaaatt tgtaatcaat
     6181 ctctcgtaga actttttcag aagaagtata gttggcattc attgaatgat tttggttctt
     6241 cgacttatga taagaactat gcaagtattt tttatgaata ctggcgcagc tttttgacag
     6301 tagataagtt ggtagaaaat ttaggtagtg tacaagcggt cttagattct tatcatttat
     6361 gggcaaatac agaaaaaact tttcccttgt tagattggtt tgttcagcag aaattaattg
     6421 aaaaagaaat ataaaaacta aaggagtaaa caatgtctaa gaaattaaca tttcactgca
     6481 tcagtggcag agacctcctt acagtcgggc tgctccacgc tcagcactag agtgcctgag
     6541 ctagacgcag tactaactcg tcttgcctcg tatgatcgac gaggcagact cgtgtcgcaa
     6601 gtaattattt tttattaagg agtattcaat gtctaagaaa ttaacatttc actgcgtcag
     6661 tggcagaaac ctccttacag tcggactgcc ctacgctcag cactagagtg cctgagctag
     6721 acgcagtact aactcgtctt gcctcgtata atcgacgagg cagactcgtg tcgcaagaaa
     6781 ttatttttta ttaaggagta ttcaatgtct aagaaattaa catttcaaga aattattttg
     6841 actttgcaac aattttggaa tgaccaagat tgtatgctta tgcaggctta tgataatgaa
     6901 aaaggtgcgg ggacaatgag tccttacact ttccttcgtg ctatcggacc tgagccatgg
     6961 aatgcagctt atgtagagcc atcacgtcgt cctgctgacg gtcgttatgg ggaaaaccct
     7021 aaccgtctct accaacacca ccaattccag gtggtcatga agccttctcc atcaaatatc
     7081 caagaacttt accttgagtc tttggaaaaa ttgggaatca atcctttgga gcacgatatt
     7141 cgttttgttg aggacaactg ggaaaaccca tcaactggtt cagctggtct tggttgggaa
     7201 gtttggcttg acggaatgga aatcactcag ttcacttatt tccaacaagt cggtggattg
     7261 gcaactggcc ctgtgactgc ggaagttacc tatggtttgg agcgcttggc ttcttacatt
     7321 caagaagtag actctgtcta tgatatcgag tgggctgatg gtgtaaaata cggagaaatc
     7381 tttatccagc ctgagtatga gcactcaaaa tattcatttg aaatttcgga ccaagaaatg
     7441 ttgcttgaaa actttgataa gtttgaaaaa gaagctggtc gtgcattaga agaaggcttg
     7501 gtacaccctg cctatgacta tgttctcaaa tgttcacata cctttaatct gcttgacgcg
     7561 cgtggtgccg tatctgtaac agagcgtgca ggctatatcg ctcgtatccg taacttggcc
     7621 cgtgtcgtag ccaaaacctt tgtcgcagaa cgcaaacgcc taggctaccc acttttggat
     7681 gaagaaacaa gagctaaact cctagcagaa gacgcagaat aaagagagtg acaaattacg
     7741 aaaatgggcg aacagagtga gccctgagcc agttgccgca gtgatgaagg tatccttagt
     7801 gaaactaagg atactaggca aaattggaga cttttggctc caattttagc aatgaaacaa
     7861 cgaagttggt tgcttgcgtg ccaatcacat aaggcaaact ggaaaataaa aagatacttt
     7921 tcggagaaaa aacatgacaa aaaacttatt agtagaactc ggtcttgaag aattaccagc
     7981 ctatgttgtt acgccaagtg aaaaacaact aggcgaaaaa atggcagcct tcctcaaggg
     8041 aaaacgcctg tcttttgaag ccattcaaac tttctcaaca ccacgtcgtt tggctgttcg
     8101 tgtaactggt cttgcagaca aacagtctga tttaacagaa gatttcaagg gtccagcaaa
     8161 gaaaattgcc ttagatagtg atggaaactt caccaaagca gctcaaggat ttgtccgtgg
     8221 gaaaggtttg actgttgaag atatcgaatt ccgtgaaatc aagggtgaag aatatgtcta
     8281 tgtcactaag gaagaaattg gtcaagcagt tgaagccatt gttccaggca ttgtggatgt
     8341 cttgaagtca ctgactttcc ctgtcagcat gcactgggcg ggaaatagct ttgaatacat
     8401 ccgccctgtt cacactttaa ctgttctctt ggatgagcaa gagtttgact tggatttcct
     8461 tgatatcaag ggaagtcgtg tgagtcgtgg ccatcgtttt ttgggacaag aaaccaagat
     8521 tcagtcagca ttgagctatg aagaagacct tcgtaagcag tttgtaatcg cagatccatg
     8581 tgaacgtgag caaatgattg ttgaccaaat caaggaaatt gaggcaaaac atggtgtacg
     8641 tatcgaaatt gatgcggatt tgctgaatga agtcttgaat ttggttgaat acccaactgc
     8701 cttcatggga agttttgatg ctaaatacct tgaagttcca gaagaagtct tggtgacttc
     8761 tatgaaggaa caccagcgtt actttgttgt tcgtgatcaa gatggaaaac tcttgccaaa
     8821 cttcatttct gttcgtaacg gaaacgcaga gcgtttgaaa aatgtcatca aaggaaatga
     8881 aaaagtcttg gtagcccgct tggaagacgg agaattcttc tggcgtgaag accaaaaatt
     8941 ggtgatttca gatcttgttg aaaaattaaa caatgtcacc ttccatgaga agattggttc
     9001 tcttcgtgaa cacatgattc gtacgggtca aatcactgta cttttggcag aaaaagctag
     9061 tttgtcagtg gatgaaacag ttgaccttgc tcgtgcagca gccatttaca agtttgactt
     9121 gttgacaggt atggttggtg aatttgacga actccaagga attatgggtg aaaaatacac
     9181 ccttcttgct ggtgaaactc cagcggtggc agctgctatt cgtgaacact acatgcctac
     9241 atcagctgaa ggagaacttc cagagagcaa ggtcggcgca gttctagcca ttgcagacaa
     9301 attggatacg attttgagtt tcttctcagt aggattgatt ccatcaggtt ctaatgaccc
     9361 ttatgccctt cgtcgtgcaa ctcaaggtgt ggttcgtatc ttggatgcct ttggttggca
     9421 cattgctatg gatgagctga ttgatagcct ttatgcattg aaatttgaca gtttgactta
     9481 tgaaaataaa gcagaggtta tggactttat caaggctcgt gttgataaga tgatgggctc
     9541 tactccaaaa gatatcaagg aagcagttct tgcaggttca aactttgttg tggcagatat
     9601 gttggaagca gcaagtgctc tcgtagaagt aagcaaggaa gaagatttta aaccatctgt
     9661 tgaatcactt tctcgtgcct ttaacctggc cgagaaggca gaaggggttg ctacggttga
     9721 ttcagcacta tttgagaatg accaagaaaa agctttggca gaagcagtag aaacactcat
     9781 tttatcagga cctgcaagtc agcaattgaa acaacttttt gcgcttagcc cagtcattga
     9841 tgctttcttt gaaaatacta tggtaatggc tgaagatcag gctgtccgtc aaaatcgttt
     9901 ggcaatcttg tcacaactaa ccaagaaagt agctaagttt gcttgtttta accaaattaa
     9961 cactaaataa aatttgataa acggacttta tcttattaca aaggagaaga aatggatccg
    10021 aaaaaaattg ctcgtatcaa tgagcttgct aaaaagaaaa aaacagaagg cttaacacca
    10081 gaagaaaaag tggaacaagc caaactacgt gaggagtaca tcgaaggtta tcgccgcgct
    10141 gttcgtcacc acattgaagg aatcaaaatt gtggacgaag aaggaaacga tgttacacca
    10201 gaaaaactac gccaagtaca acgtgaaaaa ggattacatg gccgtagtct tgatgatcca
    10261 aattcataat aatactcttc gaaaatcaaa ttcaaaccac gtcagcttca ccttgccgta
    10321 cttaagtaca gcctgcggct agcttcctag tttgctcttt gattttcatt gagtatatgt
    10381 attctttctt ttaacaaaga tagatgaaac gataacaaag agactagcag tttgtgtttg
    10441 ctagtctttt ttcgctaaaa aaggaaccat aatggttcct aaaaactatc attagtaact
    10501 tgcaccggct gtagcgtctg cgtcaccacc gtggcctcca gcatcccctg aatcagaagc
    10561 gccagaagta gcatcggcgt ctccatgacc tccggcagca ggagcaaatg gtccgctacc
    10621 acccaccaaa cgttgaccag tctcttttag gtaccagtca agccatggtt ggaagttaaa
    10681 gacgatttca ttgataccag cgtatgatcc atcaggatag tacattgctt ggtagttgtg
    10741 agtgttgata acacctgcag gagaacctgg aacgatcgta cggacgtatt cttggtttcc
    10801 gttgcgaagt gttccgataa cccactctac gttcttcata cgtgctggtg gaagagaacc
    10861 atgaacagtc gacatacggc tacctgattg aggtggtaca cgtttagcga acatagtgtc
    10921 tggatcttgg tgagcgttgt tgtagtagag gaattggttg ttgtcgtcag cgtatgtcaa
    10981 ttcaaatggc atagctttca agaacatatc aatttggtta actgttagga taccgtggtc
    11041 caatttgaca taggtatcac cagaaacagc accagtgaat gctgcaactt tttctaccca
    11101 ttctggatcg tcagggtcaa cttctgtgat ggttgtagcg attggttttc cacaatccaa
    11161 gtcttctgat tcgattggtt ttggtttttt caatttcgaa acgactccta cgtatttaac
    11221 aaagttatct aagcaagttt caaggaattt aacagtgcct tcgttggtga tatttccgtt
    11281 gttatcaaaa gcttccttag ctttaccaag aaggaattcg ttacctggaa gcgtgtaggc
    11341 attaacacct ggagcatcaa ggattttacg aaggtgaact tgagcacgtg atgttccttg
    11401 gtcatagtat gatgcaccca caatcataac aggcttgttt tcaaatggat gaacttcgta
    11461 tgaaagccat tcaagtacag atttgagtga agctgagata gtgtggttat gctcaggagt
    11521 agcaatgata acaccatctg cacgagtaat tttgttatat aaataacgta attggaaact
    11581 ttcatcccat ttttcatctt ggttaaacat tggaacttcg tcaatttcaa gaacttctaa
    11641 ttcaaatttg agtttgaagt agcgacggat aaattccaag agcttacggt tatatgattg
    11701 atcgtagttt gatccaacaa gtccaacaaa tttcattctt tttggtctcc tatcttacaa
    11761 attttcccag tcaaagtctt cagcatcttt gcgaagtaat tcttgtgcat tacgtaattt
    11821 ttctgtgatt tttacaaaga tacggaagtc atcaaagatg gcatccaatt tcttgataac
    11881 atcaaggtca accaagtcgc cacttgggtt aaatgcttga agagagtgtg agagcaagaa
    11941 ttcatctgga agaacatttg ccttgatttc aggagcattc aagatttgac gaagttgcaa
    12001 ttgggcacga gatgaaccaa gcgtaccgta agaagcacct gtaatcatga ttggtttgtt
    12061 caaaagtggg taaataccat aagacaacca agcaagagcg ctcatcaaaa cagctggaat
    12121 agagtgatca tactcaggag taccgataat aacgccatct gcctcttcga ttttagcagc
    12181 aatttccaat atttcagcag gtacttgctt gtcagctggt ttgttgaaga caggaatggc
    12241 cttgatttca acaagttcaa tttcagcttt gtcagtaaag tgtttttgca tgtattgaag
    12301 caattgacgg tttgtagaac gttttgaatt tgttccaaca atagcaataa gttttaacat
    12361 gagatttcct ttctcttttt acataataca attttaaaat tccattgaaa cagttgtctc
    12421 tatagagtag gaattcctga agaacagctt aggtggcctt ctttatcgat gaggatgact
    12481 tcgatgccct ccaaactttc gacttgccag aggatagaag caggtctttc tccaaagagt
    12541 cgagtcgtcc agatttcgcc atcgactgat ttatcagaga tgattgttag actcgctagt
    12601 tccgtttcaa caggatatcc tgtttgactg tcaaaaatgt gatggtaatc ttgtccatcg
    12661 acggtcaggt gacgttcata aatgcctgaa gtcacgacag atttattgac aacagggatg
    12721 gtcattaaat gatttcccct aggattggct gggtcttgaa tcccgatttg ccatgggtta
    12781 tcccctcttg cctgattttt tccaatggtc aggatattcc ctcccagatt gatcaaggca
    12841 gaagtcaccc cctctttcct aagaaattgg gcaaccttat ccgcactgta tcctttggct
    12901 aaacaaccta gatcgatctt cattcctttc tgttttaaaa acacagtaga agtagaagaa
    12961 tctaactcga taccatgagg attgattaga ggcagcaccg attcaatttc ttgaggctgg
    13021 gcgaccttgg catctgaaaa accgatacgc caggtttgaa ttaagggacc aatgctgata
    13081 ttgaggtggc tagagagcgc taggctatgc tctaacccaa gtgaaatcag ctcaaacagg
    13141 tctggatgaa ccgtgacggg ggctattcct gcttgataat tgatttccat caactcagat
    13201 tcttgactat tggcgttgaa gcggtattca agttctttga gcaagtcaaa ggatttttgg
    13261 agaaagatat cggcttgctc atccactaat gaaatagtga tagtagtccc cattagccgt
    13321 tcagaatgtg aacgaagagt caagctacca actcctttct cttatagaaa ataagttgta
    13381 atatcaaata atcatctaaa ttgaagccct tacatttcat tttcatgtta ttataatacc
    13441 ataaagttag aattttcaca aacaaaattt ggaaaaagtc aagaaatatg ctcataaaat
    13501 tcatcaggct tgaaaacagg ataaatgggg aattattttt gataaaaaat gctgaaataa
    13561 tagtaccccc cttgtaaacg ctaacggtaa atggtatact agtaaggtaa atttagaatg
    13621 aaggcaggaa atttttatga gtaaaatcgt tgtagtcggt gctaaccacg ctggtacagc
    13681 atgtatcaat accatgttgg ataattttgg aaatgagaac gaaattgttg tatttgacca
    13741 aaactctaac atctctttcc taggatgtgg aatggctctt tggattggtg aacaaattga
    13801 cggtgctgaa ggcttgttct attctgataa agaaaaattg gaagctaaag gtgctaaagt
    13861 ttacatgaac tcacctgttc tttcaatcga ctatgataac aaagtagtta cagcggaagt
    13921 tgaaggaaaa gagcacaaag aatcatacga aaaattgatt ttcgctacag gctctacacc
    13981 aatcttgcca ccaatcgaag gtgttgaaat tgttaaagga aaccgcgaat ttaaagcaac
    14041 tcttgaaaac gtacaattcg tgaaattgta ccaaaatgct gaagaagtta tcaataaact
    14101 ttctgacaag agccaacacc tcgaccgtat cgccgttgtt ggtggtggtt acatcggtgt
    14161 tgaacttgct gaagcctttg aacgtcttgg aaaagaagtt gtccttgttg atatcgttga
    14221 tactgtcttg aacggttact atgacaaaga cttcacacaa atgatggcga agaacttgga
    14281 agatcacaac atccgcttgg ctctaggtca aactgttaaa gcaatcgaag gtgacggtaa
    14341 agttgaacgc ttgattactg acaaagaaag ctttgacgtg gatatggtta tccttgcagt
    14401 tggtttccgt ccaaacacag cccttgcagg tggtaagatc gaactcttcc gcaacggtgc
    14461 cttccttgta gacaagaaac aagaaacatc tatcccagac gtttacgctg ttggtgactg
    14521 tgcgactgtt tatgacaatg ctcgtaaaga tacaagctat atcgctcttg cttcaaatgc
    14581 tgttcgcact ggtatcgttg gtgcctacaa tgcttgtgga catgaattgg aaggaatcgg
    14641 tgttcaaggt tcaaatggta tctcaatcta cggtcttcac atggtttcaa ctggtttgac
    14701 tcttgaaaaa gcgaaagctg ctggttacaa cgcaactgaa acaggcttta acgatcttca
    14761 aaaaccagaa ttcatgaaac atgacaacca tgaagtagca attaagattg tctttgacaa
    14821 agatagccgt gaaattcttg gtgcccaaat ggtttcacat gatattgcaa ttagcatggg
    14881 aatccacatg ttctcacttg ctatccaaga gcatgtgaca attgataaat tggcattgac
    14941 agacctcttc ttcttgccac acttcaacaa accatacaac tacatcacaa tggctgccct
    15001 tacggctgaa aaataaaaat gaatgagcta tctggcctta agttaaggtc agatagtttt
    15061 tagctaattt gtccccatac aattatagtt tttttatctt gtgcttcatt ctgttctgac
    15121 ttaaaatgaa aaggtagcta ccaatacaaa tgatgaggat aaaacaaatg actgaaaatc
    15181 gttatgaact aaataaaaac ttggcacaga tgctcaaggg tggtgttatt atggatgtgc
    15241 agaatcctga acaggctcgt atcgcagaag ctgctggtgc ggcagctgtg atggccttgg
    15301 aacgaattcc ggctgatatt cgtgcagctg gaggagtttc ccgcatgagc gacccaaaga
    15361 tgattaagga aatccaagaa gcggttagta ttccagtaat ggctaaggtc agaatcgggc
    15421 attttgttga agctcagatt ttagaggcta ttgaaattga ttatatcgac gagagtgaag
    15481 ttctatctcc agctgatgac cgtttccatg tggacaagaa agaattccaa gttccttttg
    15541 tctgtggtgc taaggatttg ggtgaagcct tgcgtcgtat cgctgaaggt gcttccatga
    15601 ttcgtaccaa aggagaacca gggacagggg atatcgtcca agctgttcgt catatgcgta
    15661 tgatgaatca ggaaattcgc cgcattcaaa acttacgtga ggacgagctt tatgttgctg
    15721 ccaaggattt gcaagtccct gtagaattgg tccaatatgt tcatgaacat ggaaaattgc
    15781 cagttgtaaa tttcgctgct ggaggtgttg caacgccagc agatgctgcg ttaatgatgc
    15841 aattaggggc agagggggtc tttgtcggtt caggtatttt caagtcagga gatcctgtta
    15901 aacgagcgag tgccattgtt aaggctgtga ctaacttccg taatcctcaa atcctagctc
    15961 aaatctctga agatttagga gaagccatgg ttggtattaa tgaaaatgaa atccaaattc
    16021 tcatggctga acgaggaaaa tagatgaaaa tcggaatatt ggccttgcaa ggggcctttg
    16081 cagaacatgc aaaagtgcta gatcaattag gtgtcgagag tgtagaactc agaaatctag
    16141 atgattttca gcaagatcag agtgacttgt cgggtttgat tttgcctggt ggtgagtcta
    16201 caaccatggg caagctctta cgtgaccaga acatgctact tcccatccga gaagccattc
    16261 tatctggctt accagtgttt gggacctgtg cgggcttaat tttgctggct aaggaaatca
    16321 cttctcagaa agagagtcat ctaggaacta tggatatggt ggtcgagcgt aatgcttatg
    16381 ggcgccaatt aggaagtttc tacacggaag cagaatgtaa gggagttggc aagattccaa
    16441 tgacctttat ccgtggtccg attatcagta gtgttggtga gggtgtagaa attttagcaa
    16501 cagtgaacaa tcaaattgtt gcagcccaag aaaaaaatat gttggtaagt tcttttcatc
    16561 cagaattgac tgatgatgtg cgcttgcacc agtactttat caatatgt
//
LOCUS       DAVFER010000047        16539 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1105170250
            SAMEA2167659-rid19724873.denovo.047, whole genome shotgun sequence.
ACCESSION   DAVFER010000047 DAVFER010000000
VERSION     DAVFER010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2167659
            Sequence Read Archive: ERR388902
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 16539)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16539)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928716.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928716.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 04:07:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,118
            CDSs (total)                      :: 2,073
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 120
            CDSs (without protein)            :: 120
            Pseudo Genes (ambiguous residues) :: 0 of 120
            Pseudo Genes (frameshifted)       :: 67 of 120
            Pseudo Genes (incomplete)         :: 47 of 120
            Pseudo Genes (internal stop)      :: 34 of 120
            Pseudo Genes (multiple problems)  :: 23 of 120
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16539
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2167659-rid19724873.denovo.047"
                     /strain="1105170250"
                     /db_xref="taxon:1313"
     gene            <1..990
                     /gene="lytB"
                     /locus_tag="VU534_001695"
     CDS             <1..990
                     /gene="lytB"
                     /locus_tag="VU534_001695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endo-beta-N-acetylglucosaminidase"
                     /protein_id="HEU1514248.1"
                     /translation="LKSDGKIAEKEWVYDSHSQAWYYFKSGGYMAKNETVDGYQLGSD
                     GKWLGGKTTNENAAYYQVVPVTANVYDSDGEKLSYISQGSVVWLDKDRKSDDKRLAIT
                     ISGLSGYMKTEDLQALDASKDFIPYYESDGHRFYHYVAQNASIPVASHLSDMEVGKKY
                     YSADGLHFDGFKLENPFLFKDLTEATNYSAEELDKVFSLLNINNSLLENKGATFKEAE
                     EHYHINALYLLAHSALESNWGRSKIAKDKNNFFGITAYDTTPYLSAKTFDDVDKGILG
                     ATKWIKENYIDRGRTFLGNKASGMNVEYASDPYWGEKIASVMMKINEKLGGKD"
     gene            complement(1051..2706)
                     /gene="pavA"
                     /locus_tag="VU534_001696"
     CDS             complement(1051..2706)
                     /gene="pavA"
                     /locus_tag="VU534_001696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_094859469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rqc2 family fibronectin-binding protein PavA"
                     /protein_id="HEU1514249.1"
                     /translation="MSFDGFFLHHIVEELRSELVNGRIQKINQPFEQELVLQIRSNRQ
                     SHRLLLSAHPVFGRIQLTQTTFENPAQPSTFIMVLRKYLQGALIESIEQVENDRIVEI
                     TVSNKNEIGDHIQATLIIEIMGKHSNILLVDKSSHKILEVIKHVGFSQNSYRTLLPGS
                     TYIAPPSTKSLNPFTIKDEKLFEILQTQELTAKNLQSLFQGLGRDTANELERILVSEK
                     LSAFRNFFNQETKPCLTETSFSPVPFANQVGEPFANLSDLLDTYYKDKAERDRVKQQA
                     SELIRRVENELQKNRHKLKKQEKELLATDNAEEFRQKGELLTTFLHQVPNDQDQVILD
                     NYYTNQPIMIALDKALTPNQNAQRYFKRYQKLKEAVKYLTDLIEETKATILYLESVET
                     VLNQAGLEEIAEIREELIQTGFIRRRQREKIQKRKKLEQYLASDGKTIIYVGRNNLQN
                     EELTFKMARKEELWFHAKDIPGSHVVISGNLDPSDAVKTDAAELAAYFSQGRLSNLVQ
                     VDMIEVKKLNKPTGGKPGFVTYTGQKTLRVTPDSKKIASMKKS"
     gene            2811..3308
                     /gene="ybeY"
                     /locus_tag="VU534_001697"
     CDS             2811..3308
                     /gene="ybeY"
                     /locus_tag="VU534_001697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HEU1514250.1"
                     /translation="MYIEMVDETGQVSKEMLQQTQEILEFAAQKLGKEDKEMAVTFVT
                     NERSHELNLEYRNTDRPTDVISLEYKPELEIAFDEEDLLENSELAEMMSEFDAYIGEL
                     FISIDKAHEQAEEYGHSFEREMGFLAVHGFLHINGYDHYTPEEEAEMFGLQEEILTAY
                     GLTRQ"
     gene            3289..3684
                     /locus_tag="VU534_001698"
     CDS             3289..3684
                     /locus_tag="VU534_001698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000378166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HEU1514251.1"
                     /translation="MDSQDNKRKWKNRDLISSLEFALTGIFTAIKEERNMRKHAVTAL
                     VVILAGFVFQVSRIEWLFLLLSIFLVVAFEIINSAIENVVDLASHYHFSMLAKNAKDM
                     AAGAVLVVSLFAALTGALIFLPRIWDLLF"
     gene            3701..4600
                     /gene="era"
                     /locus_tag="VU534_001699"
     CDS             3701..4600
                     /gene="era"
                     /locus_tag="VU534_001699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HEU1514252.1"
                     /translation="MTFKSGFVAILGRPNVGKSTFLNHVMGQKIAIMSDKAQTTRNKI
                     MGIYTTDKEQIVFIDTPGIHKPKTALGDFMVESAYSTLREVDTVLFMVPADEARGKGD
                     DMIIERLKAAKVPVILVVNKIDKVHPDQLLSQIDDFRNQMDFKEIVPISALQGNNVSR
                     LVDILSENLDEGFQYFPSDQITDHPERFLVSEMVREKVLHLTREEIPHSVAVVVDSMK
                     RDEETDKVHIRATIMVERDSQKGIIIGKGGAMLKKIGSMARRDIELMLGDKVFLETWV
                     KVKKNWRDKKLDLADFGYNEREY"
     gene            4649..5473
                     /gene="mutM"
                     /locus_tag="VU534_001700"
     CDS             4649..5473
                     /gene="mutM"
                     /locus_tag="VU534_001700"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001114577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HEU1514253.1"
                     /translation="MPELPEVETVCRGLEKLIIGKKISSIEIRYPKMIKTDLEEFQRE
                     LPSQIIESMGRRGKYLLFYLTDKVLISHLRMEGKYFYYPDQGPERKHAHVFFHFEDGG
                     TLVYEDVRKFGTMELLVPDLLDVYFISKKLGPEPSEQDFDLQVFQSALAKSKKPIKSH
                     LLDQTLVAGLGNIYVDEVLWRAQVHPARPSQTLTAEEATAIHDQTIAVLGQAVEKGGS
                     TIRTYTNAFGEDGSMQDFHQVYDKTGQECVRCGTIIEKIQLGGRGTHFCPNCQRRD"
     gene            5473..6078
                     /locus_tag="VU534_001701"
     CDS             5473..6078
                     /locus_tag="VU534_001701"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HEU1514254.1"
                     /translation="MGKIIGITGGIASGKSTVTNFLRQQGFQVVDADAVVHQLQKPGG
                     RLFEALVQHFGQEIILENGELNRPLLASLIFSNPDEREWSKQIQGEIIREELATLREQ
                     LAQTEEIFFMDIPLLFEQDYSDWFAETWLVYVDRDAQVERLMKRDQLSKDEAESRLAA
                     QWPLEKKKDLASQVLDNNGNQNQLLNQVHILLEGGRQDDRD"
     gene            6065..7264
                     /locus_tag="VU534_001702"
     CDS             6065..7264
                     /locus_tag="VU534_001702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter PmrA"
                     /protein_id="HEU1514255.1"
                     /translation="MTEINWKDNLRIAWFGNFLTGASISLVVPFMPIFVENLGVGSQQ
                     VAFYAGLAISVSAISAALFSPIWGILADKYGRKPMMIRAGLAMTITMGGLAFVPNIYW
                     LIFLRLLNGVFAGFVPNATALIASQVPKEKSGSALGTLSTGVVAGTLTGPFIGGFIAE
                     LFGIRTVFLLVGSFLFLAAILTICFIKEDFQPVAKEKAIPTKELFTSVKYPYLLLNLF
                     LTSFVIQFSAQSIGPILALYVRDLGQTENLLFVSGLIVSSMGFSSMMSAGVMGKLGDK
                     VGNHRLLVVAQFYSVIIYLLCANASSPLQLGLYRFLFGLGTGALIPGVNALLSKMTPK
                     AGISRVFAFNQVFFYLGGVVGPMAGSAVAGQFGYHAVFYATSLCVAFSCLFNLIQFRT
                     LLKVKEI"
     gene            7264..7413
                     /gene="rpmG"
                     /locus_tag="VU534_001703"
     CDS             7264..7413
                     /gene="rpmG"
                     /locus_tag="VU534_001703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEU1514256.1"
                     /translation="MRVKINLKCSSCGSINYLTSKNSKTHPDKIEVLKYCPKERKVTL
                     HLESK"
     gene            7453..7686
                     /gene="secG"
                     /locus_tag="VU534_001704"
     CDS             7453..7686
                     /gene="secG"
                     /locus_tag="VU534_001704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HEU1514257.1"
                     /translation="MYNLLLTILLVLSVVIVIAIFMQPTKNQSSNVFDASSGDLFERS
                     KARGFEAVMQRLTGILVFFWLAIALALTVLSSR"
     gene            7788..10142
                     /gene="rnr"
                     /locus_tag="VU534_001705"
     CDS             7788..10142
                     /gene="rnr"
                     /locus_tag="VU534_001705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HEU1514258.1"
                     /translation="MKDRIKEYLQDKGKVTVNDLAQALGKDSSKDFRELIKTLSLMER
                     KHQIRFEEDGSLTLEIKKKHEITLKGIFHAHKNGFGFVSLEGEEDDLFVGKNDVNYAI
                     DGDTVEVVIKKVADRNKGTAAEAKIIDILEHSLTTVVGQIVLDQEKPKYAGYIRSKNQ
                     KISQPIYVKKPALKLEGTEVLKVFIDKYPSKKHDFFVASVLDVVGHSTDVGIDVLEVL
                     ESMDIVSEFPEAVVKEAESVPDAPSQKDMEGRLDLRDEITFTIDGADAKDLDDAVHIK
                     ALKNGNLEFGVHIADVSYYVTEGSALDKEALNRATSVYVTDRVVPMLPERLSNGICSL
                     NPQVDRLTQSAIMEIDKHGRVVNYTITQTVIKTSFRMTYSDVNDILAGDEEKRKEYHK
                     IVSSIELMAKLHETLENMRVKRGALNFDTNEAKILVDKQGKPVDIVLRQRGIAERMIE
                     SFMLMANETVAEHFSKLDLPFIYRIHEEPKAEKVQKFIDYASSFGLRIYGTASEISQE
                     ALQDIMRAVEGEPYADVLSMMLLRSMQQARYSEHNHGHYGLAADYYTHFTSPIRRYPD
                     LLVHRMIRDYGRSKEIAEHFEQVIPEIATQSSNRERRAIEAEREVEAMKKAEYMEEYV
                     GEEYDAVVSSIVKFGLFVELPNTVEGLIHITNLPEFYHFNERDLTLRGEKSGITFRVG
                     QQIRIRVERADKMTGEIDFSFVPSEFDVIEKGLKQSSRSGRGRDSNRRSDKKEDKRKS
                     GRSNDKRKHSQKDKKKKGKKPFYKEVAKKGAKHGKGRGKGRRTK"
     gene            10105..10572
                     /gene="smpB"
                     /locus_tag="VU534_001706"
     CDS             10105..10572
                     /gene="smpB"
                     /locus_tag="VU534_001706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HEU1514259.1"
                     /translation="MAKGEGKVVAQNKKARHDYTIVDTLEAGMVLTGTEIKSVRAARI
                     NLKDGFAQVKNGEVWLSNVHIAPYEEGNIWNQEPERRRKLLLHKKQIQKLEQEIKGTG
                     MTLVPLKVYIKDGYAKLLLGLAKGKHDYDKRESIKRREQNRDIARVMKAVNQR"
     gene            10588..11448
                     /gene="tehB"
                     /locus_tag="VU534_001707"
     CDS             10588..11448
                     /gene="tehB"
                     /locus_tag="VU534_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent methyltransferase TehB"
                     /protein_id="HEU1514260.1"
                     /translation="MEKLVAYKRMPLWNKQTMPEAVQQKHNTKVGTWGKITVLKGALK
                     FIELTEEGEVLAEHLFEAGADNPMAQPQAWHRVEAATDDVEWYLEFYCKPEDYFAKKY
                     NTNPVHSEVLEAMQTVKQGKALDLGCGQGRNSLFLAQQDFDVTAVDQNGLALEILQSI
                     VEQEDLDMPVGLYDINSASIEQEYDFIVSTVVLMFLQADRIPAIIQNMQEKTSVGGYN
                     LIVCAMDTEDYPCSVNFPFTFKEGELADYYKDWELVKYNENPGHLHRRDENGNRIQLR
                     FATLLAKKIK"
     gene            11521..12474
                     /gene="coiA"
                     /locus_tag="VU534_001708"
     CDS             11521..12474
                     /gene="coiA"
                     /locus_tag="VU534_001708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000495911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CoiA"
                     /protein_id="HEU1514261.1"
                     /translation="MFVARDARGELVNVLEDKLEKQAYTCPACGGQLHLRQGPSVRTH
                     FAHKSLKDCDFFFENESPEHLANKESLYHWLKKETKVQLEYPLSELKQIADVFVNGNL
                     ALEVQCSPLPQKVLKERSEGYRSQGYQVLWLLGQKLWLKERLTRLQQGFLYFSQNMGF
                     YVWELDKEKQVLRLKYLIYQDLRGKLHYQIKEFSYGQGSLLEILRLPYKRQKISHFTV
                     SEDKDICRYIRQQLYYQNLFWMKEQAEAYQKGENILTYGLKEWYPQIRPIVGKFFQIE
                     QDLTSYYQHFYTYYQKNPQNDWQKLYPPAFYQQYFLKNMVE"
     gene            12493..14295
                     /gene="pepF"
                     /locus_tag="VU534_001709"
     CDS             12493..14295
                     /gene="pepF"
                     /locus_tag="VU534_001709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HEU1514262.1"
                     /translation="MVLQRNEINEKDTWDLSTIYPTDQAWEEALKDLTEQLETVAQYE
                     GHLLDSADNLLEITEFSLEMERQIEKLYAYAHMKNDQDTREAKYQEYYAKAMTLYSQL
                     DQAFSFYEPEFMEISEKQYADFLEAQPKLQVYQHYFDKLLQGKDHVLSQREEELLAGA
                     GEIFGSASETFAILDNADIVFPYVLDDDGKEVQLSHGTYTRLMESKKREVRRGAYQAL
                     YATYEQFQHTYAKTLQTNVKVQNYRAKVRNYKSARHAALAANFVPESVYDNLVAAVRK
                     HLPLLHRYLELRSKILGISDLKMYDVYTPLSSVEYSFTYQEALKKAEDALAVLGEDYL
                     SRVKRAFSERWIDVYENQGKRSGAYSGGSYDTNAFMLLNWQDNLDNLFTLVHETGHSM
                     HSSYTRETQPYVYGDYSIFLAEIASTTNENILTEKLLEEVEDDATRFAILNNFLDGFR
                     GTVFRQTQFAEFEHAIHQADQNGEVLTSDFLNKLYADLNQEYYGLSKEDNPEIQYEWA
                     RIPHFYYNYYVYQYSTGFAAASALAEKIVHGSQEDRDRYIDYLKAGKSDYPLNVMRKA
                     GVDMEKEDYLNDAFAVFERRLNEFEALVEKLGLA"
     gene            14297..15010
                     /locus_tag="VU534_001710"
     CDS             14297..15010
                     /locus_tag="VU534_001710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HEU1514263.1"
                     /translation="MVESYSKNANHNMRRPVVKEEIVDLMRQRQKQVTGFLKELEDFA
                     RKENIPIIPHETVAYFRFLMETMQPKNILEIGTAIGFSALLMAEHAPNAKITTIDRNP
                     EMIGFAKENFAQFDSRKQITLLEGDAVDVLSTLTESYDFVFMDSAKSKYIVFLPEILK
                     HLEVGGVVVLDDIFQGGDVAKDIMEVRRGQRTIYRGLQKLFDATLDNPELTATLVPLG
                     DGILMLRKNVADVQLSESE"
     gene            15077..16018
                     /gene="prsA"
                     /locus_tag="VU534_001711"
     CDS             15077..16018
                     /gene="prsA"
                     /locus_tag="VU534_001711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase PrsA"
                     /protein_id="HEU1514264.1"
                     /translation="MKKKLLAGAITLLSVATLAACSKGSEGADLISMKGDVITEHQFY
                     EQVKSNPSAQQVLLNMTIQKVFEKQYGSELDDKEVDDTIAEEKKQYGENYQRVLSQAG
                     MTLETRKAQIRTSKLVELAVKKVAEAELTDEAYKKAFDEYTPDVTAQIIRLNNEDKAK
                     EVLEKAKAEGADFAQLAKDNSTDEKTKENGGEITFDSASTEVPEQVKKAAFALDVDGV
                     SDVITATGTQAYSSQYYIVKLTKKTEKSSNIDDYKEKLKTVILTQKQNDSTFVQSIIG
                     KELQAANIKVKDQAFQNIFTQYIGGGDSSSSSSTSNE"
     gene            complement(16136..16477)
                     /locus_tag="VU534_001712"
                     /pseudo
     CDS             complement(16136..16477)
                     /locus_tag="VU534_001712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
BASE COUNT         4974 a         3092 c         3700 g         4773 t
ORIGIN      
        1 ctcaaatctg atgggaaaat agctgaaaaa gaatgggtct acgattctca tagtcaagct
       61 tggtactact tcaaatctgg tggctacatg gcgaaaaatg agacagtaga tggttatcag
      121 cttggaagcg atggtaaatg gcttggagga aaaactacaa atgaaaatgc tgcttactat
      181 caagtagtgc ctgttacagc caatgtttat gattcagatg gtgaaaagct ttcctatata
      241 tcgcaaggta gtgtcgtatg gctagataag gatagaaaaa gtgatgacaa gcgcttggct
      301 attactattt ctggtttgtc aggctatatg aaaacagaag atttacaagc gctagatgct
      361 agtaaggact ttatccctta ttatgagagt gatggccacc gtttttatca ctatgtggct
      421 cagaatgcta gtatcccagt agcttctcat ctttctgata tggaagtagg caagaaatat
      481 tattcggcag atggcctgca ttttgatggt tttaagcttg agaatccctt ccttttcaaa
      541 gatttaacag aggctacaaa ctacagtgct gaagaattgg ataaggtatt tagtttgcta
      601 aacattaaca atagcctttt ggagaacaag ggcgctactt ttaaggaagc cgaagaacat
      661 taccatatca atgctcttta tctccttgcc catagtgccc tagaaagtaa ctggggaaga
      721 agtaaaattg ccaaagataa gaataatttc tttggcatta cagcctatga tacgacccct
      781 tacctttctg ctaagacatt tgatgatgtg gataagggaa ttttaggtgc aaccaagtgg
      841 attaaggaaa attatatcga taggggaaga actttccttg gaaacaaggc ttctggtatg
      901 aatgtggaat atgcttcaga cccttattgg ggcgaaaaaa ttgctagtgt gatgatgaaa
      961 atcaatgaga agctaggtgg caaagattag tactataagt gaatatgatt tgagtgaata
     1021 gtaagttaaa aatcctgatt tcaagtaaaa tcaggatttt ttcatggatg caattttttt
     1081 ggagtctggt gtgacgcgga gggtcttttg tcctgtgtaa gtgacaaagc cgggttttcc
     1141 accagttggt ttattgagtt ttttgacttc aatcatatct acctgcacca gattcgacag
     1201 gcgcccttga gagaagtagg cagctaactc tgctgcgtct gtcttgactg catcagatgg
     1261 gtcaagattt cctgagatga caacatggct tccaggaatg tccttagcat ggaaccaaag
     1321 ttcctccttg cgggccattt taaaggtcaa ttcctcattt tgaagattgt ttcgtccgac
     1381 atagatgatg gttttgccat cgcttgctag atattgttct agttttttgc gtttctggat
     1441 tttctcccgt tgtcttctgc ggataaaacc tgtttgaatc aattcttcac ggatttcagc
     1501 gatttcttcc agtccagctt ggttgaggac ggtttctaca ctttccagat agagaatagt
     1561 ggctttggtt tcttcaatca aatcagtcaa gtatttgaca gcttctttga gtttctgata
     1621 ccgtttaaaa tagcgttggg cattctggtt gggagtcaga gccttatcaa gcgcaatcat
     1681 gataggttgg ttggtatagt agttgtctag gataacctgg tcttggtcgt taggcacttg
     1741 gtggaggaag gttgtcagca attctccttt ttgacgaaat tcttcagcgt tgtctgtcgc
     1801 cagtaactct ttttcctgtt ttttgagttt gtgtcggttt ttctgaagtt cattttcaac
     1861 acgacgaatc agttcactgg cctgctgttt gacgcggtcg cgctcagcct tatccttata
     1921 gtaggtgtcc aacaaatcag aaagatttgc aaaaggctct cccacctgat ttgcaaaagg
     1981 aactggactg aaggaagtct cagtcaagca tggcttggtt tcttgattga aaaaatttcg
     2041 gaaagcggaa agtttttcac taaccagtat cctttccaat tcatttgccg tatcgcgtcc
     2101 cagaccttga aagaggcttt gaagattttt tgctgttagt tcttgggttt gcaggatttc
     2161 aaagagcttt tcatccttga tagtaaaagg attgagagat tttgtacttg gcggagcgat
     2221 ataggtcgat cctggaagta aggtgcggta gctattttgt gaaaagccga cgtgtttgat
     2281 aacttcgagg attttatgac tgcttttatc gaccagtaga atattactgt gtttccccat
     2341 aatttcgata atcaaggtag cctggatatg gtctccaatc tcgtttttat tggaaactgt
     2401 aatttccaca atacggtcat tttccacttg ctcaatcgac tcaatcaggg ccccctgcaa
     2461 atactttctc aaaaccatga taaaggtaga aggttgagct ggattttcaa aagtcgtttg
     2521 ggtcagctga atgcgtccaa aaactggatg ggcagaaagg agcaggcgat ggctttggcg
     2581 attgctgcgg atttgcaaga ccaactcttg ttcaaaaggc tgattgattt tctggatgcg
     2641 accattcact aattcgcttc gcaattcctc aactatgtgg tgtaaaaaaa atccgtcaaa
     2701 tgacatcgtt ctctccttgt gattgtattc catagtatta tatcaaaaag gtagaataaa
     2761 atcatggaaa tgtggtataa taaagccaag taaagagaaa cgagaagcac atgtatattg
     2821 aaatggtaga tgaaactggt caagtttcaa aagaaatgtt gcaacaaacc caagaaattt
     2881 tggaatttgc agcccaaaaa ttaggaaaag aagacaagga gatggcagtc acttttgtga
     2941 ccaatgagcg tagtcatgaa cttaatctgg agtaccgtaa caccgaccgt ccgacagatg
     3001 tcatcagcct tgagtataaa ccagaattgg aaattgcctt tgacgaagag gatttgcttg
     3061 aaaattcaga attggcagag atgatgtctg agtttgatgc ctatattggg gaattgttca
     3121 tctctatcga taaggctcat gagcaggccg aagaatatgg tcacagcttt gagcgtgaga
     3181 tgggcttctt ggcagtacac ggctttttac atattaacgg ctatgatcac tacactccgg
     3241 aagaagaagc ggagatgttc ggtttacaag aagaaatttt gacagcctat ggactcacaa
     3301 gacaataaac gaaaatggaa aaatcgtgac ttgatatcca gtttagaatt tgctttgaca
     3361 ggtattttta ctgctatcaa ggaagaacgc aatatgcgaa aacacgcagt gacggctcta
     3421 gtggtcatcc ttgcaggttt tgtttttcag gtgtcacgaa tcgaatggct ctttctccta
     3481 ttgagtattt tcttggtagt agcctttgag attatcaact ctgctattga aaatgtggtg
     3541 gatttggcca gtcactatca cttttccatg ctggctaaaa atgccaagga tatggcggcc
     3601 ggcgcggtat tagtggtttc tcttttcgca gccttaacag gcgcattgat ttttctccca
     3661 cgaatctggg atttattatt ttaaacagta agaggaaatt atgactttta aatcaggctt
     3721 tgtagccatt ttaggacgtc ccaatgttgg gaagtcaacc tttttaaatc acgttatggg
     3781 gcaaaagatt gccatcatga gtgacaaggc gcagacaacg cgcaataaaa tcatgggaat
     3841 ttacacgact gataaggagc aaattgtctt tatcgacaca ccagggattc acaagcctaa
     3901 aacagctctc ggagatttca tggttgagtc tgcctacagt acccttcgcg aagtggacac
     3961 tgttcttttc atggtgcctg ctgatgaagc gcgtggtaag ggggacgata tgattatcga
     4021 gcgtctcaag gctgccaagg ttcctgtgat tttggtggtg aataaaatcg ataaggtcca
     4081 tccagaccag ctcttgtctc agattgatga cttccgtaat caaatggact ttaaggaaat
     4141 tgttccaatc tcagcccttc agggaaataa cgtgtctcgt ctagtggata ttttgagtga
     4201 aaatctggat gaaggtttcc aatatttccc gtctgatcaa atcacagacc atccagaacg
     4261 tttcttggtt tcagaaatgg ttcgcgagaa agtcttgcac ctaactcgtg aagagattcc
     4321 gcattctgta gcagtagttg ttgactctat gaaacgagac gaagagacag acaaggttca
     4381 catccgtgca accatcatgg tcgagcgcga tagccaaaaa gggattatca tcggtaaagg
     4441 tggcgctatg cttaagaaaa tcggtagcat ggcccgtcgt gatatcgaac tcatgctagg
     4501 agacaaggtc ttcctagaaa cctgggtcaa ggtcaagaaa aactggcgcg ataaaaagct
     4561 agatttggct gactttggct ataatgaaag agaatactaa gtagaggtag gctcatgcct
     4621 gcttcttgtt tttacagaag gaggacttat gcctgaatta cctgaggttg aaaccgtttg
     4681 tcgtggctta gaaaaattga ttataggaaa gaagatttcg agtatagaaa ttcgctaccc
     4741 caagatgatt aagacggatt tggaagagtt tcaaagggaa ttgcctagtc agattatcga
     4801 gtcaatggga cgtcgtggaa aatatttgct tttttatctg acagacaagg tcttgatttc
     4861 ccatttgcgg atggagggca agtattttta ctatccagac caaggacctg aacgcaagca
     4921 tgcccatgtt ttctttcatt ttgaagatgg tggcacgctt gtttatgagg atgttcgcaa
     4981 gtttggaacc atggaactct tggtgcctga ccttttagac gtctacttta tttctaaaaa
     5041 attaggtcct gaaccaagcg aacaagactt tgatttacag gtctttcaat ctgcccttgc
     5101 caagtccaaa aagcctatca aatcccatct cctagaccag accttggtag ctggacttgg
     5161 caatatctat gtggatgagg ttctctggcg agctcaggtt catccagcta gaccttccca
     5221 gactttgaca gcagaagaag cgactgccat tcatgaccag accattgctg ttttgggcca
     5281 ggctgttgaa aaaggtggct ccaccattcg gacttatacc aatgcctttg gggaagatgg
     5341 aagcatgcag gactttcatc aggtctatga taagactggt caagaatgtg tacgctgtgg
     5401 taccatcatt gagaaaattc aactaggcgg acgtggaacc cacttttgtc caaactgtca
     5461 aaggagggac tgatgggaaa aatcatcgga atcactgggg gaattgcctc tggtaagtca
     5521 actgtgacaa attttctaag acagcaaggc tttcaagtag tggatgccga cgcagtcgtc
     5581 caccaactac agaaacctgg tggtcgtctg tttgaggctc tagtacagca ctttgggcaa
     5641 gaaatcattc ttgaaaacgg agaactcaat cgccctctcc tagctagtct catcttttca
     5701 aatcctgatg aacgagaatg gtctaagcaa attcaagggg agattatccg tgaggaactg
     5761 gctactttga gagaacagtt ggctcagaca gaagagattt tcttcatgga tattccccta
     5821 ctttttgagc aggactacag cgattggttt gctgagactt ggttggtcta tgtggaccga
     5881 gatgcccaag tggaacgctt aatgaaaagg gaccagttgt ccaaagatga agctgagtct
     5941 cgtctggcag cccagtggcc tttagaaaaa aagaaagatt tggccagcca ggttcttgat
     6001 aataatggca atcagaacca gcttcttaat caagtgcata tccttcttga gggaggtagg
     6061 caagatgaca gagattaact ggaaggataa tctgcgcatt gcctggtttg gtaattttct
     6121 gacaggagcc agtatttctt tggttgtacc ttttatgccc atcttcgtgg aaaatctagg
     6181 tgtagggagt cagcaagtcg ctttttatgc aggcttagca atttctgtct ctgctatttc
     6241 cgcggcgctc ttttctccta tttggggtat tcttgctgac aaatacggcc gaaaacccat
     6301 gatgattcgg gcaggtcttg ctatgactat cactatggga ggcttggcct ttgtcccaaa
     6361 tatctattgg ttaatctttc ttcgtttact aaacggtgta tttgcaggtt ttgttcctaa
     6421 tgcaacggca ctgatagcca gtcaggttcc aaaggagaaa tcaggctctg ccttaggtac
     6481 tttgtctaca ggcgtagttg caggtactct aactggtccc tttattggtg gctttatcgc
     6541 agaattattt ggcattcgta cagttttctt actggttggt agttttctat ttttagctgc
     6601 tattttgact atttgcttta tcaaggaaga ttttcaacca gtagccaagg aaaaggctat
     6661 tccaacaaag gaattattta cctcggttaa atatccctat cttttgctca atctcttttt
     6721 aaccagtttt gtcatccaat tttcagctca atcgattggc cctattttgg ctctttatgt
     6781 acgcgactta gggcagacag agaatcttct ttttgtctct ggtttgattg tgtccagtat
     6841 gggcttttcc agcatgatga gtgcaggagt catgggcaag ctaggtgaca aggtgggcaa
     6901 tcatcgtctc ttggttgtcg cccagtttta ttcagtcatc atctatctcc tctgtgccaa
     6961 tgcctctagc ccccttcaac taggactcta tcgtttcctc tttggattgg gaaccggtgc
     7021 cttgattccc ggggttaatg ccctactcag caaaatgact cccaaagccg gcatttcgag
     7081 ggtctttgcc ttcaatcagg tattctttta tctgggaggt gttgttggtc ccatggcagg
     7141 ttctgcagta gcaggtcaat ttggctacca tgctgtcttt tatgcgacaa gcctttgtgt
     7201 tgcctttagt tgtctcttta acctgattca atttcgaaca ttattaaaag taaaggaaat
     7261 ctagtgcgag taaaaatcaa tctcaaatgc tcctcttgtg gcagtatcaa ttacctaacc
     7321 agtaaaaatt caaaaaccca tccagacaag attgaggttt taaagtattg tcccaaggaa
     7381 agaaaagtaa ccctacatct tgaatctaag tagattttat ggtaaaataa tagggatttt
     7441 aaggagtttg atatgtataa cctattatta accattttat tagtattatc tgttgtgatt
     7501 gtgattgcaa ttttcatgca accaaccaaa aaccaatcca gcaatgtatt tgatgccagt
     7561 tcaggtgatt tgtttgaacg cagtaaagct cgcggttttg aagctgtaat gcagcgtttg
     7621 acagggattt tagtcttttt ctggctagcc attgccttag cattgacggt attatcaagt
     7681 agataagaaa ataatgggca ggactaggtc tttgcctctt tttattttta aaggatgttt
     7741 gagaaggttt tacagtaaaa gaaaattaaa aaatctagaa agaaaatatg aaagatagaa
     7801 taaaagaata tttacaagac aagggaaagg tgactgttaa tgatttggct caggctttgg
     7861 gaaaagacag ttccaaggat tttcgtgagt tgattaaaac cttgtcctta atggaaagaa
     7921 agcaccaaat tcgttttgaa gaagatggta gtctgacatt agaaattaag aaaaaacatg
     7981 agattaccct caaggggatt tttcatgccc ataaaaatgg ctttggcttt gttagtctgg
     8041 aaggcgagga ggacgacctt tttgtaggga aaaatgatgt caactatgct attgatggtg
     8101 ataccgtcga ggtagtgatt aagaaagtcg ctgaccgcaa taagggaaca gcagcagaag
     8161 ccaaaattat tgatatccta gaacacagtt tgacaacagt tgtcgggcaa atcgttctgg
     8221 atcaggaaaa acctaagtat gctggctata ttcgttcaaa aaatcagaaa atcagtcaac
     8281 cgatttatgt taagaaacca gccctaaaat tagaaggaac agaagttctc aaagtcttta
     8341 tcgataaata cccaagcaag aaacatgatt tctttgtcgc gagtgttctc gatgtagtgg
     8401 gacactcaac ggatgtcgga attgatgttc ttgaggtctt ggaatcaatg gacattgtat
     8461 ccgagtttcc agaagctgtt gttaaggaag cagaaagtgt gcctgatgct ccgtctcaaa
     8521 aggatatgga aggtcgtctg gatctaagag atgaaattac ctttaccatt gacggtgcgg
     8581 atgccaagga cttggacgat gcagtgcata tcaaggctct gaaaaatggc aatctggagt
     8641 ttggggttca catcgcagat gtttcttatt atgtgaccga ggggtctgcc cttgacaagg
     8701 aagcccttaa ccgtgcgact tctgtttacg tgacagaccg agtggtgcca atgcttccag
     8761 aacgactatc aaatggcatc tgctctctca atccccaagt tgaccgcctg acccagtctg
     8821 ctattatgga gattgataaa catggtcgtg tggtcaacta taccattaca caaacagtta
     8881 tcaagaccag ttttcgtatg acctatagcg atgtcaatga tatcctagct ggcgatgaag
     8941 aaaagagaaa agaatatcat aaaattgtat caagtatcga actcatggcc aagcttcatg
     9001 aaactttaga aaacatgcgt gtgaaacgtg gagctctcaa ttttgatacc aatgaagcga
     9061 agattttagt ggataaacaa ggtaagcctg ttgatatcgt tcttcggcag cgtggtattg
     9121 ccgagcggat gattgagtct tttatgttga tggctaatga aacagttgcc gaacatttca
     9181 gcaagttgga tttgcctttt atctatcgaa ttcacgagga gcctaaggct gaaaaggttc
     9241 agaagtttat tgattatgct tcgagttttg gcttgcgcat ttatggaact gccagtgaga
     9301 ttagtcagga ggcacttcaa gacatcatgc gtgctgttga gggagaacct tatgcagatg
     9361 tattgtccat gatgcttctt cgctctatgc agcaggctcg ttattcggag cacaatcacg
     9421 gccactatgg actagctgct gactattata ctcactttac cagtccaatt cgtcgttatc
     9481 cagaccttct tgttcaccgt atgattcggg attacggccg ttctaaggaa atagcagagc
     9541 attttgaaca agtgattcca gagattgcga cccagtcttc caaccgtgaa cgtcgtgcca
     9601 tagaagctga gcgtgaagtc gaagccatga aaaaggctga gtatatggaa gaatacgtgg
     9661 gtgaagagta tgatgcagtt gtatcaagta ttgtcaaatt cggtctcttt gtcgaattgc
     9721 caaacacagt tgaaggcttg attcacatca ctaatctgcc tgaattttat catttcaatg
     9781 agcgtgattt gactcttcgt ggagaaaaat caggtatcac tttccgagtg ggtcagcaga
     9841 tccgtatccg tgttgaaaga gcggataaaa tgactggaga gattgatttt tcattcgtac
     9901 ctagtgagtt tgatgtgatt gaaaaaggct tgaaacagtc tagtcgtagt ggcagagggc
     9961 gtgattcaaa tcgtcgttcg gataagaagg aagacaagag aaaatcagga cgctcaaatg
    10021 ataagcgtaa gcattcacaa aaagacaaga agaaaaaagg aaagaaacct ttttacaagg
    10081 aagtagctaa gaaaggagcc aagcatggca aagggcgagg gaaaggtcgt cgcacaaaat
    10141 aaaaaggcac gccacgacta tacaatcgta gatacgctag aggcagggat ggtcctgact
    10201 ggaactgaaa tcaagagtgt acgagctgct cgaattaatc tcaaggatgg ctttgctcaa
    10261 gtgaaaaatg gagaagtttg gctgagcaat gttcatatcg cgccttacga agagggcaat
    10321 atctggaacc aggaaccaga acgtcgtcgt aaactcctgc tccataaaaa gcaaattcaa
    10381 aaattggaac aagagatcaa agggacagga atgaccttag ttccccttaa ggtctatata
    10441 aaagatggct acgctaagct tcttttagga cttgccaaag ggaagcatga ctatgacaaa
    10501 cgggagtcta tcaaacgtcg tgagcaaaat cgagatatcg cgcgtgtgat gaaagctgtt
    10561 aatcagcgat aaaaagagga attgaaaatg gaaaaattag ttgcctataa acgcatgcct
    10621 ttgtggaata aacaaacaat gcctgaagct gttcagcaaa agcacaatac aaaagttggg
    10681 acttggggga aaattactgt cttgaaggga gctctcaagt ttattgaatt gacagaagaa
    10741 ggggaagttc tagctgaaca cctctttgaa gcaggggcag acaatccaat ggcccaacct
    10801 caagcctggc accgagtgga agctgccaca gatgatgtgg aatggtactt ggaattttat
    10861 tgtaaacctg aggattattt tgctaaaaaa tacaatacca atcctgttca ttcagaggtc
    10921 ctagaggcca tgcagacagt gaaacaaggg aaagctttgg atttgggttg tggtcagggg
    10981 cgtaattctc tttttctagc ccagcaagat tttgatgtga cggctgtaga tcaaaatgga
    11041 ctagctcttg aaatcttgca aagcattgtg gagcaggaag atttggacat gcctgttggc
    11101 ctttacgata tcaattcagc tagcattgaa caagaatatg attttatcgt ttcaacagtt
    11161 gttctcatgt ttctacaagc ggaccgcatt ccagctatta ttcaaaatat gcaggagaaa
    11221 accagtgttg gtggttacaa ccttatcgtt tgtgccatgg acacggagga ttatccttgc
    11281 tcggttaact tcccattcac ctttaaagaa ggagaactgg cagactatta caaggattgg
    11341 gaattggtta agtacaatga aaatccaggc catttgcacc gtcgcgatga gaatggcaat
    11401 cgtattcaac tacgctttgc gaccttacta gctaagaaaa tcaagtaaac acacatgaag
    11461 attaggaatt ttcctgatct tttttctttt ttacgaatga tatagaaaag gagggaattc
    11521 atgtttgttg cgagagatgc taggggagaa ttggtaaatg tgttagagga taaacttgag
    11581 aagcaagcat acacctgccc agcttgtgga ggccagctcc atttgcgtca aggaccaagt
    11641 gtacggacgc attttgccca taaatcctta aaagactgtg attttttctt tgaaaatgaa
    11701 agtccagaac acctggccaa taaggaatcc ctctatcact ggttgaaaaa agagacaaag
    11761 gttcaattag agtacccgct ttcagaactt aaacagattg cggatgtatt tgtaaatggc
    11821 aatctagctc tagaagttca gtgtagtccc ttgcctcaga aagtccttaa agagcgaagt
    11881 gagggctatc gtagtcaggg ttaccaagta ctgtggttgc tgggtcaaaa actgtggctc
    11941 aaggagcgtt tgactcgtct acagcaaggt tttctttatt tcagtcaaaa catgggcttt
    12001 tatgtttggg aattagacaa ggaaaaacaa gttttaagac tcaaatacct gatttaccag
    12061 gatctccgcg gtaaactcca ttatcaaatc aaggaatttt cctatggtca aggtagttta
    12121 ttggaaatat tgcgtcttcc ctataagaga caaaaaatat ctcattttac agtttctgag
    12181 gacaaggaca tctgtcgcta tatccggcaa caactttatt atcaaaatct cttttggatg
    12241 aaagaacaag cagaagccta tcaaaaggga gaaaatatcc tgacttatgg actgaaagaa
    12301 tggtatccac aaattcgacc aatagtgggc aaatttttcc agattgaaca agacttgact
    12361 agctattatc agcactttta tacctattac caaaaaaatc ctcaaaatga ttggcaaaag
    12421 ctttatccac cagcctttta tcagcaatat ttcttgaaaa atatggtaga atagaaagga
    12481 tggaggaatc taatggtatt acaaagaaat gaaataaatg aaaaagatac atgggatcta
    12541 tcaacgatct acccaactga ccaggcttgg gaagaagcct taaaagattt aacagaacaa
    12601 ttggagacag tagcccagta tgaaggccat ctcttggata gtgcggataa cctactagaa
    12661 atcactgaat tttctcttga aatggaacgc cagatagaga agctttacgc ttatgctcat
    12721 atgaagaatg accaggatac acgtgaagct aagtatcaag agtactatgc caaggccatg
    12781 acactctaca gccagttaga ccaagccttt tcattctatg agcctgaatt tatggagatt
    12841 agcgaaaagc agtatgctga ctttttagaa gctcaaccaa agctgcaggt ttatcaacac
    12901 tattttgaca agcttttgca aggcaaggat cacgttcttt cacaacgtga agaagaatta
    12961 ttggctggag ctggagaaat ctttggttca gcaagtgaaa ccttcgctat cttggacaat
    13021 gcggatattg tgttccctta tgtcctagac gatgatggta aagaagttca gctatctcat
    13081 gggacttaca cacgtttgat ggagtctaaa aaacgtgagg ttcgccgtgg tgcctatcaa
    13141 gctctttatg cgacttacga acaattccaa cacacctatg ccaaaacctt gcaaaccaat
    13201 gttaaggtgc aaaattaccg tgctaaagtt cgtaactaca agagtgctcg tcatgcagcc
    13261 ctcgcagcga attttgttcc agaaagtgtt tatgacaatt tggtagcagc agttcgcaag
    13321 catttgccac tcttacatcg ctatcttgag cttcgttcaa aaatcttggg gatttcagat
    13381 ctcaagatgt acgatgtcta cacaccgctt tcatctgttg aatacagttt tacctaccaa
    13441 gaagccttga aaaaagcaga agatgctttg gcagtcttgg gtgaggatta cttgagccgt
    13501 gttaaacgtg ccttcagcga gcgttggatt gatgtttacg aaaatcaagg caagcgttca
    13561 ggtgcctact ctggtggttc ttatgatacc aatgccttta tgcttctcaa ctggcaagac
    13621 aatctggaca atctctttac tcttgttcat gaaacaggtc acagtatgca ttcaagctat
    13681 actcgtgaaa ctcagcctta tgtttacggg gattactcta tctttttggc tgagattgcc
    13741 tcaactacca atgaaaatat cttgacggag aaattattgg aagaagtgga agacgacgca
    13801 acacgctttg ctattctcaa taacttccta gatggtttcc gtggaacagt tttccgccaa
    13861 actcaatttg ctgagtttga acacgccatt caccaagcag atcaaaatgg ggaggtcttg
    13921 acaagcgatt tcctaaataa actctacgca gacttgaacc aagagtatta tggtttgagt
    13981 aaggaagaca atcctgaaat ccaatacgag tgggctcgca ttccacactt ctactataac
    14041 tactatgtat atcaatattc aactggcttt gcggccgcct cagccttggc tgaaaaaatt
    14101 gtccatggta gtcaagaaga ccgtgaccgc tatatcgact acctcaaggc aggtaagtcg
    14161 gactatccac ttaatgtcat gagaaaagct ggtgttgata tggagaagga agactacctc
    14221 aacgatgcct ttgcagtctt tgaacgccgt ttaaatgagt ttgaagccct tgttgaaaaa
    14281 ttaggattgg cataaaatgg ttgaatcgta tagtaagaat gctaaccata acatgcgtcg
    14341 tcctgtcgtc aaagaagaaa ttgtagactt gatgcgtcag cgtcaaaagc aggtcacagg
    14401 tttcttgaaa gaattggaag actttgcccg caaggaaaat attcctatta ttccccatga
    14461 aacggttgct tatttccgtt ttcttatgga aaccatgcag cctaaaaata ttctggaaat
    14521 tgggacggct atcggttttt cagctctctt gatggctgaa catgcgccaa atgctaagat
    14581 tacaactatt gatcgtaatc cagaaatgat tggttttgcc aaggaaaatt ttgcccagtt
    14641 tgacagtcgc aagcaaatca ctctcctaga gggagatgcg gtggatgtct tatctacact
    14701 gacagagtct tatgatttcg tctttatgga ttctgccaag tctaaataca tcgtctttct
    14761 gccagaaatc ctcaaacatt tggaagttgg tggtgtggtt gtcttggatg atatttttca
    14821 aggtggtgat gttgccaagg atattatgga agtccgtcgt ggtcagcgaa ccatttatcg
    14881 aggccttcaa aaattatttg atgcaacctt agacaatcca gaactcaccg caacattagt
    14941 gcctttagga gatggtattc tcatgcttcg taaaaatgta gcagatgttc aactgtctga
    15001 aagcgaatga ttttcagaaa aatttaagaa aaaatagtaa aatagataga gtaacactta
    15061 tctcaaagga gtagacatga agaaaaaatt attggcaggt gccatcacac tattatcagt
    15121 agcaacttta gcagcttgtt cgaaagggtc agaaggtgca gaccttatca gcatgaaagg
    15181 ggatgtcatt acagaacatc aattttatga gcaagtgaaa agcaaccctt cagcccaaca
    15241 agtcttgtta aatatgacca tccaaaaagt ttttgaaaaa caatatggct cagagcttga
    15301 tgataaagag gttgatgata ctattgccga agaaaaaaaa caatatggcg aaaactacca
    15361 acgtgtcttg tcacaagcag gtatgactct tgaaacacgt aaagctcaaa ttcgtacaag
    15421 taaattagtt gagttggcag ttaagaaggt agcagaagct gaattgacag atgaagccta
    15481 taagaaagcc tttgatgagt acactccaga tgtaacggct caaatcatcc gtcttaataa
    15541 tgaagataag gccaaagaag ttctcgaaaa agccaaggca gaaggtgctg attttgctca
    15601 attagccaaa gataattcaa ctgatgaaaa aacaaaagaa aatggtggag aaattacctt
    15661 tgattctgct tcaacagaag tacctgagca agtcaaaaaa gccgctttcg ctttagatgt
    15721 ggatggtgtt tctgatgtga ttacagcaac tggcacacaa gcctacagta gccaatatta
    15781 cattgtaaaa ctcactaaga aaacagaaaa atcatctaat attgatgact acaaagaaaa
    15841 attaaaaact gttatcttga ctcaaaaaca aaatgattca acatttgttc aaagcattat
    15901 cggaaaagaa ttgcaagcag ccaatatcaa ggttaaggac caagccttcc aaaatatctt
    15961 tacccaatat atcggtggtg gagattcaag ctcaagcagt agtacatcaa acgaatagtc
    16021 caaatcaatg agtcagggaa aaaactcgac ttcaggaaaa aatgaagcaa acattcccac
    16081 aataaaacgc atagtacaag gtttgtactg ccccccaaaa agttagacaa ttaatttatc
    16141 cgaaggattt agttctgtat tgcacagagc taagtccttt tagttttatc ttaattctct
    16201 tattgttgta ataatcaata tagtctataa tggctcgttc caattgatta agtgatttaa
    16261 atgttttctc atagccataa aacatttcgg attttaaaat gccaaagaaa gattccatcc
    16321 taccgttgtc ttggctgttg cccttacgtg acatggatgc ttgaattccc ttactctcta
    16381 ggaagcgatg ataagaatcg tgttgatatt gccagccttg gtcactatgg agaatcgtat
    16441 tctcgtagtg cttctctttg aatgcctgtt ccaacattaa cgatcaatca atttaatcat
    16501 gtacctaaga ttagaattgt ttatcccaaa tttatttga
//
LOCUS       DAVFER010000048        15383 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1105170250
            SAMEA2167659-rid19724873.denovo.048, whole genome shotgun sequence.
ACCESSION   DAVFER010000048 DAVFER010000000
VERSION     DAVFER010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2167659
            Sequence Read Archive: ERR388902
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 15383)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15383)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928716.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928716.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 04:07:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,118
            CDSs (total)                      :: 2,073
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 120
            CDSs (without protein)            :: 120
            Pseudo Genes (ambiguous residues) :: 0 of 120
            Pseudo Genes (frameshifted)       :: 67 of 120
            Pseudo Genes (incomplete)         :: 47 of 120
            Pseudo Genes (internal stop)      :: 34 of 120
            Pseudo Genes (multiple problems)  :: 23 of 120
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15383
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2167659-rid19724873.denovo.048"
                     /strain="1105170250"
                     /db_xref="taxon:1313"
     gene            complement(186..1748)
                     /gene="guaA"
                     /locus_tag="VU534_001713"
     CDS             complement(186..1748)
                     /gene="guaA"
                     /locus_tag="VU534_001713"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000065723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HEU1514265.1"
                     /translation="MSNISTDLQDVEKIIVLDYGSQYNQLISRRIREIGVFSELKSHK
                     ISAAEVREVNPVGIILSGGPNSVYEDGSFDIDPEIFELGIPILGICYGMQLLTHKLGG
                     KVVPAGDAGNREYGQSTLTHTPSALFESTPDEQTVLMSHGDAVTEIPADFVRTGTSAD
                     CPYAAIENPDKHIYGIQFHPEVRHSVYGNDILRNFALNICKAKGDWSMDNFIDMQIKK
                     IRETVGDKRVLLGLSGGVDSSVVGVLLQKAIGDQLICIFVDHGLLRKGEADQVMDMLG
                     GKFGLNIVKADAAKRFLDKLAGVSDPEQKRKIIGNEFVYVFDDEASKLKDVKFLAQGT
                     LYTDVIESGTDTAQTIKSHHNVGGLPEDMQFELIEPLNTLYKDEVRALGTELGMPDHI
                     VWRQPFPGPGLAIRVMGEITEEKLETVRESDAILREEIAKAGLDRDIWQYFTVNTGVR
                     SVGVMGDGRTYDYTIAIRAITSIDGMTADFAKIPWEVLQKISVRIVNEVDHVNRIVYD
                     ITSKPPATVEWE"
     gene            1890..2588
                     /locus_tag="VU534_001714"
     CDS             1890..2588
                     /locus_tag="VU534_001714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000936186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEU1514266.1"
                     /translation="MLPAYIKIHDQIKKDIDEYRWAIGERLPSERDLAEQFAVSRMTL
                     RQAVSLLVEEGVLERRVGSGTFVSSTRVQEKMRGTTSFTEIVKSQGKVPSSQLISYKK
                     TIPNEQEVAKLGIFPTDNIIRMERVRYADQVPLVYEVASIPEKFIKDFKKEEITSHFF
                     QTLQKHGYRIGKSQQTIYARLAKEKIAHYLEVEKGHAILGLTQVSYLEDGTAFEYVKS
                     QYVGERFEFYLENN"
     gene            complement(2631..3527)
                     /locus_tag="VU534_001715"
     CDS             complement(2631..3527)
                     /locus_tag="VU534_001715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HEU1514267.1"
                     /translation="MSNSLKGTLLTVVAGIAWGLSGTSGQYLMAHGISALVLTNLRLL
                     IAGGILMLLAYATAKDKILVFLKDRKSLLSLLIFALIGLFLNQFAYLSAIQETNAGTA
                     TVLQYVCPVGILIYSCIKDRVAPTLGEIVSIIFAIGGTFLIATHGQLDQLSMTPAGLF
                     WGLFSALTYALYIILPIALIKKWGSSLVIGVGMVIAGLVALPFTGVLQADIPTSLDFL
                     LAFAGIILIGTVFAYTAFLKGASLIGPVKSSLLASIEPISAIFFAFLIMNEQFYPIDF
                     LGMAMILFAVTLISLKDLFLEK"
     gene            complement(3536..4471)
                     /locus_tag="VU534_001716"
     CDS             complement(3536..4471)
                     /locus_tag="VU534_001716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HEU1514268.1"
                     /translation="MKWTKIIKKIEEQIEAGIYPGASFAYFKDNQWTEFYLGQSDPEH
                     GLQTEAGLVYDLASVSKVVGVGTVCTFLWEIGQLDIDRLVIDFLPESDYPDITIRQLL
                     THATDLDPFIPNRDLLTAPELKEAMFHLNRRSQPAFLYSDVHFLLLGFILERIFNQDL
                     DVILKDQVWKPWGMTETKFGPVELAVPTVRGVEAGIVHDPKARLLGRHAGSAGLFSTI
                     KDLQIFLEHYLADDFARDLNQNFSPLDDKERSLAWNLEGDWLDHTGYTGTFIMWNRQK
                     QEATIFLSNRTYEKDERAQWILDRNQVMNLIRKEE"
     gene            complement(4468..5193)
                     /locus_tag="VU534_001717"
     CDS             complement(4468..5193)
                     /locus_tag="VU534_001717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001102210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CppA family protein"
                     /protein_id="HEU1514269.1"
                     /translation="MNVNQIVRIIPTLKANNRKLNETFYIETLGMKALLEESAFLSLG
                     DQTGLEKLVLEEAPSMRTRKVEGRKKLARLIVKVENPLEIEGILSKTDSIHRLYKGQN
                     GYAFEIFSPEDDLILIHAEDDIASLVEVGEKPEFQTDLASISLSKFEISMELHLPTDI
                     ESFLESSEIGASLDFIPAQGQDLTVDNTVTWDLSMLKFLVNELDIASLRQKFESTEYF
                     IPKSEKFFLGKDRNNVELWFEEV"
     gene            complement(5277..5912)
                     /locus_tag="VU534_001718"
     CDS             complement(5277..5912)
                     /locus_tag="VU534_001718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-alkyl-2-acetylglycerophosphocholine esterase"
                     /protein_id="HEU1514270.1"
                     /translation="MAVQLLENWLLKEQEKIQTKYRHLNHISVVEPNILFIGDSIVEY
                     YPLQELFGTSKTIVNRGIRGYQTGLLLENLDAHLYGGAVDKIFLLIGTNDIGKDVPVN
                     EALNNLEAIIQSVARDYPLTEIKLLSILPVNEREEYQQAVYIRSNEKIQNWNQAYQEL
                     ASAYMQVEFVPVFDCLTDQAGQLKKEYTTDGLHLSIAGYQALSKSLKDYLY"
     gene            complement(5914..6741)
                     /locus_tag="VU534_001719"
     CDS             complement(5914..6741)
                     /locus_tag="VU534_001719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEU1514271.1"
                     /translation="MMIKVIATDMDGTLLDARGQLDLPRLEKILDQLDQRGIRFVIAT
                     GNEIHRMRQLLSPLVDRVVLVVANGARIFENNELIQAQTWDDAIVNKALTHFKGRACQ
                     DQFVVTGMKGDFVKEGTIFTDLESFMTPEMIEKFYQRMQFVDELTSDLFGGVLKMSMV
                     VGEERLSSVLEEINALFDGRVRAVSSGYGCIDILQAGIHKAWGLEELLKRWDLKSQEI
                     MAFGDSENDVEMLEMAGIAYAMENADEKAKAVATALAPANSQGGVYQVLENWLEKGE"
     gene            complement(6763..7689)
                     /locus_tag="VU534_001720"
                     /pseudo
     CDS             complement(6763..7689)
                     /locus_tag="VU534_001720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809127.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="CapA family protein"
     gene            8350..8961
                     /locus_tag="VU534_001721"
     CDS             8350..8961
                     /locus_tag="VU534_001721"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HEU1514272.1"
                     /translation="MSAIERITKAAHLIDMNDIIREGNPTLRAIAEEVTFPLSDQEII
                     LGEKMMQFLKHSQDPVMAEKMGLRGGVGLAAPQLDISKRIIAVLVPNIVEEGETPQEA
                     YDLEAIMYNPKIVSHSVQDAALGEGEGCLSVDRNVPGYVVRHARVTVDYFDKDGEKHR
                     IKLKGYNSIVVQHEIDHINGIMFYDRINEKDPFAVKDGLLILE"
     gene            9006..9734
                     /gene="rlmB"
                     /locus_tag="VU534_001722"
     CDS             9006..9734
                     /gene="rlmB"
                     /locus_tag="VU534_001722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HEU1514273.1"
                     /translation="MKTNDIVYGVHAVTEALLANTGNKLYLQEDLRGKNVEKVKELAT
                     EKKVSISWTSKKSLSEITEGAVHQGFVLRVSEFAYSELDYILAKTRQEENPLLLILDG
                     LTDPHNLGSILRTADATNVSGVIIPKHRTVGVTPVVAKTATGAIEHVPIARVTNLSQT
                     LDKLKDEGFWTFGTDMNGTPCHKWNTKGKIALIIGNEGKGISSNIKKQVDEMITIPMN
                     GHVQSLNASVAAAILMYEVFRNRL"
     gene            complement(9773..10684)
                     /gene="trxB"
                     /locus_tag="VU534_001723"
     CDS             complement(9773..10684)
                     /gene="trxB"
                     /locus_tag="VU534_001723"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HEU1514274.1"
                     /translation="MYDTIIIGAGPAGMTAALYAARSNLKVALIEGGLPGGQMNNTSD
                     IENYPGYANISGPELAEKMFEPLENLGVEHIYGYVENVEDHGDFKKVMTDDQTYETRT
                     VIVATGSKHRPLGVPGEEELNSRGVSYCAVCDGAFFRDQDLLVVGGGDSAVEEALFLT
                     RFAKTVTIVHRRDQLRAQKVLQDRAFANEKISFIWDSVVREIKGENRVESVVFENVKT
                     GQVTEQAFGGVFIYVGLDPLSDFVKELNIQDQAGWIVTDNHMKTAVDGIFAVGDVRLK
                     DLRQVTTAVGDGAIAGQEAYKFITEHS"
     gene            complement(10750..10974)
                     /locus_tag="VU534_001724"
     CDS             complement(10750..10974)
                     /locus_tag="VU534_001724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4059 family protein"
                     /protein_id="HEU1514275.1"
                     /translation="MLLQLFSLYFESLILTTILVLIFLGIWIGLRAMSGVDKTARARQ
                     AHLYDMIMIGVLVVPVLSFAVMSLILVFKA"
     gene            complement(11052..11795)
                     /locus_tag="VU534_001725"
     CDS             complement(11052..11795)
                     /locus_tag="VU534_001725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEU1514276.1"
                     /translation="MIKISNLSKSFSGQTVLDHLDLDIQKGEVVALIGSSGAGKSTFL
                     RSLNYLETPDSGSIQIDGFSVDFSKITQEEILALRRKLSMVFQQFNLFERRTALDNVK
                     EGLVVVKKLSDQEATKIAKEELAKVGLSDRENHYPRHLSGGQKQRVALARALAMKPDV
                     LLLDEPTSALDPELVGEVEKSIADAAKSGQTMILVSHDMSFVAQVADKILFLDKGKII
                     ESGTPDEIIHTPKEERTKEFFASYKRTYI"
     gene            complement(11795..12595)
                     /locus_tag="VU534_001726"
     CDS             complement(11795..12595)
                     /locus_tag="VU534_001726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001103446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEU1514277.1"
                     /translation="MNVTTILASDWYQNLMQLIPDGKLFSLRSVFDGIPRIVQQLPTT
                     IMLTIGGALFGLVLALLFAIVKINRVKILYPLQAFFVSFLKGTPILVQLMLTYYGIPL
                     ALKALNQQWGTGLNINAIPAAAFAIVAFAFNEAAYASETIRAAILSVNPGEIEAARSL
                     GMTRAQVYRRVIIPNAAVVATPTLINSLIGLTKGTSLAFSAGVVEVFAQAQILGGADY
                     RYFERFISVALVYWVVNIGIESLGRFIERKMAISAPDTVQTDVKGDLR"
     gene            complement(12753..13109)
                     /locus_tag="VU534_001727"
     CDS             complement(12753..13109)
                     /locus_tag="VU534_001727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000889075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HEU1514278.1"
                     /translation="MLEFIEYPKCSTCKKAKQELNQLGVDYKAVHIVEETPSQEVILN
                     WLETSGFELKQFFNTSGIKYRELGLKDKVGSLSNQEAAELLASDGMLLKRPILVENGT
                     VKQIGYRKSYEELGLK"
     gene            complement(13103..13633)
                     /locus_tag="VU534_001728"
     CDS             complement(13103..13633)
                     /locus_tag="VU534_001728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HEU1514279.1"
                     /translation="MQKKYVKILYSSPIGILSLVADDHYLYGIWVQEQKHFERGLGDE
                     TIEEVVSHPILDPVIACLDDYFKGKPQDLSNLLLAPIGTNFEKRVWDYLQGIPYGQTV
                     TYGQIAQDLQVASAQAIGGAVGRNPWSILVPCHRVLGAGKRLTGYAAGVEKKAWLLEH
                     EGVDFKDRSNRRRSTC"
     gene            complement(13633..14127)
                     /locus_tag="VU534_001729"
     CDS             complement(13633..14127)
                     /locus_tag="VU534_001729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU1514280.1"
                     /translation="MEIRLAFPNEVDAIMQVMEDAKKCLADAGSDQWQNGYPNADVII
                     DDIISGQAYVALEEGELLAYAAVTKSPEEAYEAIYEGNWQAGESEYLVFHRIAVAADV
                     QGKGVAQTFLEGLIEGFDYLDFRSDTHAENKVMQHIFEKLGFKQVGKMPVDGERLAYQ
                     KLKK"
     gene            14262..14708
                     /locus_tag="VU534_001730"
     CDS             14262..14708
                     /locus_tag="VU534_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HEU1514281.1"
                     /translation="MKTTFSYPKWAEIPNIDLYLDQVLLYVNQVCAPISPNKDKGLTA
                     SMVNNYVKNGYLTKPDKKKYQRQQIARLIAITTLKSVFSIQEIAQTLNTLQTQASSDQ
                     LYDAFVDYMNQGIDPANPIIQTSCQTVKLYHQTLDLIDHTQEEVIQ"
     gene            14705..15352
                     /locus_tag="VU534_001731"
     CDS             14705..15352
                     /locus_tag="VU534_001731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001097995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HEU1514282.1"
                     /translation="MNTSLKLSKQLSFGEEIANSVTHAVGAVIMLILLPISSIYSYEA
                     HGFLSSIGVSIFVISLFLMFLSSTIYHSMAYGSTHKYVLRIIDHSMIYVAIAGSYTPV
                     VLTLMNNWFGYLIIVIQWGTTIFGILYKIFAKKVNEKFSLALYLIMGWLVLAIIPAII
                     SQTTPVFWSLMVTGGLCYTVGAGFYAKKKPYFHMIWHLFILAASALQYIAIVYYM"
BASE COUNT         4608 a         3498 c         2734 g         4543 t
ORIGIN      
        1 attctcatta tatatatcaa aagaccgcag cttgaaaact acggtctaat tttttgtcca
       61 aatgtaaacc acttggaact attattcaat ttattctttt tagcaaatgt tcccgtttta
      121 atcccagtta cagtttttaa tcctctgtaa ccgttgattt tacaaagctt ttaatttttt
      181 tgcgattatt cccactcaac tgttgcaggt ggtttacttg taatatcgta gacgatacgg
      241 ttaacatgat ccacttcatt tacgatacgt actgagattt tttgaagtac ttcccatgga
      301 attttggcaa aatcagcagt cataccatcg atagaagtga tagcacggat tgcaatcgtg
      361 tagtcatacg tacgaccgtc acccataaca ccgactgaac gaacgcctgt gttaacagtg
      421 aagtattgcc aaatatcgcg gtcaagtcca gctttagcga tttcttcacg aagaatagcg
      481 tctgattcac gaacggtttc aagtttctct tcagtgattt cacccatgac acggatagca
      541 agtcctggtc ctgggaatgg ttggcgccat acgatatggt ctggcatacc aagctctgta
      601 ccaagagcac gaacttcatc cttgtaaaga gtattgagtg gttcaatcaa ttcaaactgc
      661 atatcttctg gaagaccacc cacgttgtgg tgtgacttga tagtttgagc tgtatccgta
      721 ccagactcga taacatctgt atataaagta ccttgagcaa ggaatttcac atctttgagc
      781 ttgcttgctt cgtcatcgaa tacatagaca aactcgttac cgatgatttt acgtttttgt
      841 tcagggtcag aaacgccagc aagtttgtca aggaaacgtt tagcagcgtc tgctttgacg
      901 atattcaaac caaacttacc accgagcatg tccataactt gatcagcttc gcctttacga
      961 agaagaccgt ggtctacgaa gatacagatc aattgatcgc caatcgcttt ttggagaaga
     1021 accccaacga cagatgagtc aacaccacct gatagaccaa gaaggacacg tttatcaccg
     1081 acggtttcac gaattttttt gatctgcatg tcaatgaaat tatccattga ccagtcacct
     1141 ttagccttac aaatgttaag ggcaaagtta cgaaggatat catttccgta tacagaatga
     1201 cgaacttctg ggtggaattg gataccgtaa atgtgtttat ctgggttttc gatggctgcg
     1261 tatgggcagt cagctgatgt acctgtacga acaaagtcag caggaatctc agtaaccgca
     1321 tcaccatggc tcatcaaaac agtctgttca tcaggtgttg attcaaaaag cgctgatggt
     1381 gtgtgagtta gggttgattg accgtattca cgatttccag catcacctgc aggaacaact
     1441 tttcctccaa gtttatgggt caataactgc ataccataac agattcccaa aattggaatt
     1501 ccgagttcga agatttctgg gtcaatatca aatgaaccat cttcatatac agaatttgga
     1561 ccacctgata gaataattcc tacaggattg acttcacgaa cttcagcagc tgaaatttta
     1621 tggcttttta gttctgaaaa aacaccaatc tcacggatac ggcgtgaaat cagctggttg
     1681 tactggctac catagtccaa tacgatgatt ttttctacat cttgcaaatc agttgaaatg
     1741 ttgctcatct ttttcctttc tcaaaagaaa tatcttttct caatattcta tcacaaataa
     1801 gggcgaatta ccaactaaac aaggcgaagt ttgacttttt ctagtttatt ggggtacaat
     1861 agagaaaaga tagaaatgaa gtgaaaaata tgctacctgc ttatataaaa atccatgatc
     1921 agataaaaaa ggatattgac gagtaccgtt gggctattgg tgagaggctt cccagtgaaa
     1981 gagatttagc tgagcagttt gcggtcagtc gcatgaccct ccgccaagcc gtatctctat
     2041 tagtcgaaga aggcgtctta gagcgccgtg taggaagcgg cacctttgtt tccagtactc
     2101 gagtacaaga aaagatgcga gggacaacca gttttactga aattgtcaaa tcccaaggta
     2161 aagttccctc tagccagctc atttcctaca aaaaaaccat tcccaatgag caagaagttg
     2221 ccaagctagg aatttttcca acggacaata ttatccgaat ggagcgggtc cgctatgccg
     2281 accaagttcc cctagtttat gaagttgctt ctattcctga aaaattcatt aaggacttta
     2341 aaaaagaaga aatcaccagt catttcttcc aaaccttgca aaaacatggc tatcgtatcg
     2401 gcaaatctca acagaccatc tatgctcgcc ttgctaaaga aaagattgcc cactatttgg
     2461 aagttgaaaa aggacatgct attcttggat tgacccaggt ttcctaccta gaagatggta
     2521 ctgcttttga atacgtaaaa agtcaatatg taggcgaacg ctttgaattt tatcttgaaa
     2581 ataattagat taccacgcaa aaactctctg tcacggacaa agagtctttt ttatttttct
     2641 aagaataaat ctttcaaaga aatcaaagtt acagcaaaca atatcattgc cataccaaga
     2701 aaatcaatgg gataaaattg ttcattcatt attaagaagg caaagaaaat cgccgatatt
     2761 ggctcaattg aagccaacaa gcttgacttg accggtccta tcagactggc tcctttaagg
     2821 aaagctgtat aggcaaagac agtcccgata aggataatgc ctgcaaacgc aaggagaaaa
     2881 tcaagactag tcgggatatc ggcctgtaga acccctgtaa aaggaagggc gaccaaacct
     2941 gctatgacca ttcccacacc aatgaccaag ctgctccccc actttttaat caaggctatg
     3001 ggtaaaatga tatacagagc ataagtcaag gcagaaaaga gaccccagaa cagaccagca
     3061 ggtgtcatgg ataactggtc caactgccca tgtgttgcga tcaggaaggt tcctccgatg
     3121 gcgaatatga tggaaactat ctctcccagt gtcggtgcca ccctatcctt gatacagcta
     3181 taaattaaaa ttccgacagg acaaacatac tgaagcaccg tcgctgttcc cgcattggtc
     3241 tcctgaatag cagacagata ggcgaattgg ttgagaaaaa gaccaatcag agcaaaaata
     3301 agaagagaca gcaaactctt tctatccttt aaaaagacca gtattttatc ctttgcagta
     3361 gcataagcca agagcatgag aattccacca gcgattaaaa gacgcaagtt agtcaagacc
     3421 agagccgaaa ttccgtgtgc cattaggtat tggccactcg ttcctgacaa cccccaagca
     3481 ataccagcca caactgttag taaagtccct tttaaactat ttgacatgtc tctccttact
     3541 cttctttgcg aatcaagttc atcacttgat tgcggtctaa tatccattga gctctctcgt
     3601 ccttttcata ggtacgattc gataggaaaa tagtggcttc ttgcttctga cgattccaca
     3661 tgataaaggt acctgtatag cccgtatggt ctagccaatc tccttccaaa ttccatgcta
     3721 aagaacgttc cttgtcatcc aaaggagaaa aattttgatt taagtctctt gcaaaatcat
     3781 ctgctaaata gtgttctaaa aagatttgta aatcctttat agtcgaaaat aaaccagcac
     3841 tcccagcatg tctacccagg agacgagcct tgggatcatg cactatgcct gcctctacac
     3901 ctctaactgt tggaacagca agctcaactg gcccaaactt agtttccgtc attccccaag
     3961 gtttccagac ttgatccttt aaaatcacat ccaaatcttg attaaaaatt ctttccaaaa
     4021 taaagcccaa cagcaaaaaa tggacatccg aataaagaaa ggctggctga cttcgtctgt
     4081 tgagatgaaa catcgcttcc tttaattcag gggctgttaa aagatcacga ttaggaataa
     4141 aaggatcaag gtctgttgca tgagtcaaga gctggcgaat agtgatgtct ggataatcac
     4201 tctcaggtaa aaaatctatt accagtctat caatatctaa ttgacctatt tcccacaaga
     4261 aggtacaaac tgtgccaacc ccaacaacct tgctgacact agctaggtca taaactagtc
     4321 ctgcctcagt ctgcaagcca tgctctgggt cactctggcc taaatagaac tctgtccatt
     4381 gattgtcctt aaaatacgca aaagaggctc cgggataaat ccctgcctcg atttgttctt
     4441 ctattttttt aataatcttg gtccacttca tacttcttca aaccacaatt caacattatt
     4501 tctatcttta ccaaggaaga atttttcaga cttaggaata aaatattcag tagactcaaa
     4561 cttctggcga agacttgcta tgtctaattc attgaccaag aacttgagca tagataagtc
     4621 ccaggtaacc gtattgtcca cagtcaaatc ctgcccctga gctggaataa aatcaaggga
     4681 tgccccaatt tcagatgatt ccaagaaact ttcgatatca gttgggagat gtaattccat
     4741 agaaatctca aatttactta aagaaattga tgccaaatct gtttgaaatt caggcttttc
     4801 tcctacttct actagacttg ctatgtcatc ttccgcatga atcaaaatca aatcatcttc
     4861 tggtgagaaa atttcaaaag cgtagccatt ttgaccttta tataatcgat gaatcgaatc
     4921 tgttttagat aagattcctt caatttctaa gggattttcc accttgacaa tcaatctagc
     4981 tagttttttt cttccctcta ccttacgagt acgcatactg ggagcttctt ctaaaaccag
     5041 cttttcaaga cccgtttggt cacctagtga cagaaaggcc gattcttcta acaaggcctt
     5101 cattccaagg gtttcaatat aaaatgtttc atttaatttt ctattattag cttttaaagt
     5161 aggaataatc cgtacaatct gatttacatt cataaattcc tccgtcactt tttattttaa
     5221 aggattttag aattttttac aagatattat gctcaaattt aacattattt agctatttag
     5281 taaagatagt ctttcaagga ttttgacaaa gcctgataac cagcaatact gaggtgcagt
     5341 ccatcagttg tatattcttt tttgagttgg cctgcttggt ctgtcaaaca atcaaatact
     5401 ggcacaaatt ccacctgcat ataggcagat gcaagctctt gataggcttg attccagttc
     5461 tgaatttttt cattcgagcg gatatagact gcctgctggt actcctctct ctcattgaca
     5521 ggcaaaatgg aaagcaattt aatctctgtc aatggataat cgcgagcaac ggattgaatg
     5581 atagcttcga gattattgag agcctcattc acaggaacat cctttccgat atcatttgtc
     5641 ccaatcagaa gaaaaatttt atctactgct ccaccatata gatgagcatc aaggttctct
     5701 agtaacagtc ctgtctgata gccacgaatt cctcgattga caatcgtctt tgaagtccca
     5761 aatagctcct gtagaggata atactcgaca atggaatccc caataaaaag aatgtttggt
     5821 tctacaacag aaatgtgatt taggtgacga tacttagttt gaattttttc ttgttccttt
     5881 aggagccaat tttctaataa ctgtactgcc acttcattct cctttttcta accagttttc
     5941 caagacttga taaactcctc cttggctgtt ggctggtgct agagcagtcg ccacagcttt
     6001 ggctttctca tcagcatttt ccatcgcata ggcaattcca gccatttcaa gcatttcaac
     6061 atcattttca ctatcaccaa aagccatgat ttcttgggat ttcaagtccc agcgcttgag
     6121 taattcctcc aagccccatg ctttatgaat cccagcttgg aggatatcaa tgcaaccata
     6181 gccactggat acagctcgga cacggccatc aaagagagca ttgatttctt ccaaaaccga
     6241 actcaaacgt tcctcaccaa caaccatgct catcttgagc acaccaccaa agaggtcaga
     6301 tgttaattca tccacaaatt gcatccgttg gtagaatttt tcaatcattt ctggagtcat
     6361 aaaactttca agatctgtaa aaatcgtacc ttccttgaca aaatcaccct tcatccccgt
     6421 tacaacaaac tggtcctgac acgctcgacc cttgaaatga gtcaaagcct tgttgacaat
     6481 ggcgtcatcc catgtctgag cctgaatcaa ttcattgttt tcaaaaatac gagcgccatt
     6541 agcaacaacc agaaccactc gatccaccaa gggactcagt agttgtctca tgcggtgaat
     6601 ttcattgccc gtcgcaatga caaaacgaat gcccctttga tccaactgat ctaaaatctt
     6661 ttccaatcgt gggagatcaa gctgacctct agcatccagc aaggtcccat ccatatctgt
     6721 cgcaattacc ttaatcatca tttactttcc tctggattca agctaatacc acttcaatcc
     6781 cacatgttca ttcatttctt tataggctgt atcaattcgt tccttagtcg cttcatctaa
     6841 ctggtcacga tgactgccat cctctataaa atcttccaaa atataagttt ggtaatgata
     6901 caagggatat ccttctggtg aaaaggttcc ctttggtgtt cgattgaccc aagtaggatg
     6961 agctttagct gttccgatag ttgtttttcc atccttcttc ttgatggtga catccatgag
     7021 aacaccacgt tcagtccact tagcattctc ttcatctccc atagattcaa ttcgttgatt
     7081 ggaaatgaag ttccccattt aatagataat gagtttctta tctccatctt tttcaaccgt
     7141 ttcagatggt tcaacaacgt gaggatgccc tccaaagata atatccgctc ccaaatcgat
     7201 catcttgtga taaagagctt tttgttcttc agttggttcc aatcgatact caacacccat
     7261 ctgaagcatg ataatggtga tatctgcttc cttctctgcc cgttcaattt caaccttcat
     7321 cttatcttcg tttaaatctg aaagataacg attatagtct tcctgagaaa tatactgctc
     7381 aattccattg aaaccatagg aataggctaa caatgcaacc ttgataccat tcacttcctt
     7441 aatgaccagc ggagcctgat cacgtggttc gtgcgtataa actccgattg gagtgattcc
     7501 agctttctca ataatatcgg ccgttgaaat aactccctca atttgcgaat ccaaaatatg
     7561 attatgagct aaatccagca catgataacc tgcctcctta atagcatcca taacttcaac
     7621 aggagcatta aagagaagat aacccgctaa ataatgatcc ttattaatgg ttccttcaaa
     7681 atcaccaata gctaaatctg ctgcttagtc cccttgcttg agccaaggag tcacatactc
     7741 aaaattttca tgaaagtcat aggtaccgtc ttctttttta gctgaaaaga aaagtccatc
     7801 gtggtagagc aaatccccgt gggccataat tctggcagtt ttttcctctt cctactcctg
     7861 agacttttgc ttagtcccct cttgagaaat agtatctcgt ttttgactag tcaagggatt
     7921 ccttggaagc tttcaaacaa caagaccaag cccattgata aaccaactgc tagcaagagt
     7981 atcgccacaa atcccttatt gctccacttg cgataactcc taaaaagttt accaagccct
     8041 tcataaaacg aaaagctaaa ccaccctgat ttcgattttg tcttctttgt atcttcgttc
     8101 tccctacttt cttatgcaag ccttttcttt ttattatatc acagataagt atttctttca
     8161 caattgaatt gaacttccta tctattttct ataaatccta aatgccataa tgctttcaat
     8221 tcttgtcatt ttgtgatatc atgtagaggt aatgaaagaa aatgaactaa tccacagtgg
     8281 cttattccaa gtataccact tgggctttgg cagtagctaa ctgcactaaa cataatataa
     8341 ggagagaaaa tgtctgcaat agaacgtatt acaaaagctg ctcacttaat tgatatgaac
     8401 gatattatcc gtgaagggaa tcctactcta cgcgcgattg ctgaggaagt cactttcccc
     8461 ctatctgacc aggaaatcat cctaggcgaa aagatgatgc aattccttaa acattcccaa
     8521 gatcctgtca tggctgaaaa aatgggactc cgcggtggtg ttggactggc tgctccccag
     8581 ttagatatct caaaacgcat tatcgctgtt ttggtaccta atattgttga agaaggcgaa
     8641 actccacagg aagcctacga tttggaagcc attatgtaca atccaaaaat cgtctctcac
     8701 tctgttcaag atgctgctct tggcgaagga gaaggttgcc tgtctgttga ccgtaacgtg
     8761 cctggctatg ttgttcgcca tgcccgcgtt actgttgact actttgacaa agatggagaa
     8821 aaacaccgta tcaaactcaa aggctacaac tccattgttg ttcagcatga aattgaccac
     8881 attaacggta tcatgtttta cgatcgcatc aatgaaaaag acccatttgc agttaaagat
     8941 ggtttactga ttcttgaata aagaaaatcc cgttgcaaga cggggttttg tgttataata
     9001 gaggcatgaa aacaaatgat attgtctatg gtgtccacgc cgttaccgaa gccctccttg
     9061 caaatacagg aaacaaactc tacctccaag aagatctccg aggtaagaat gttgagaaag
     9121 tcaaggaact agctacagaa aagaaggtgt ccatttcttg gacatcaaaa aaatctctct
     9181 ctgagattac tgaaggtgct gttcatcaag gttttgttct acgagtgtct gaatttgcct
     9241 atagcgagct agattacatc cttgcaaaaa cacgccaaga agaaaatcca cttctattga
     9301 ttctagatgg tctaaccgat ccccataatc tgggttctat cttgcgaaca gccgatgcga
     9361 ccaatgtttc aggtgtcatc attcccaagc accgtactgt cggagtaact cctgtcgttg
     9421 ccaaaacagc cacaggtgct attgaacacg ttccaattgc ccgagtgacc aacctcagtc
     9481 aaaccttaga taaacttaag gatgaaggtt tctggacctt tggaacggat atgaacggta
     9541 ctccttgcca caagtggaat acaaaaggga aaatcgccct catcattgga aatgaaggaa
     9601 aaggtatctc tagcaacatc aaaaaacagg tcgatgaaat gattaccatt ccgatgaatg
     9661 gacatgttca aagccttaat gccagtgttg ctgcggccat tctcatgtac gaagttttcc
     9721 gaaatagact ataaaaaagt ttccagtcat ctgattggaa acttttttat gattaactat
     9781 gttctgtaat gaatttatag gcttcttgac cagcgatagc tccatctcca accgctgttg
     9841 ttacttggcg aaggtctttc aagcgaacat ctccaactgc aaagataccg tcgactgcag
     9901 ttttcatgtg gttatctgtc acaatccatc ctgcctgatc ttggatattc aattctttaa
     9961 caaaatcgct aagagggtcc aaaccaacat agataaagac accaccgaag gcttgttctg
    10021 tcacttgacc tgttttcaca ttttcaaata cgactgattc tactcggttt tcacccttga
    10081 tttcccttac tacagaatcc cagataaagc tgattttttc attcgcaaag gcgcgatctt
    10141 gtaaaacctt ttgggcacga agttggtcac gacggtgaac aatggtaaca gtcttagcaa
    10201 aacgagtcaa gaagagggct tcttcaacag ctgaatctcc accaccaact accaataaat
    10261 cttggtcacg gaagaaagca ccatcacaca cagcacagta agaaacacca cgactgttca
    10321 gttcttcttc tccaggcact cccaaaggac ggtgtttaga accagttgct acgataactg
    10381 tacgtgtttc atatgtttgg tcatcagtca tcactttctt aaaatcacca tggtcttcga
    10441 cattttcaac ataaccataa atgtgctcaa caccaagatt ttcaagtggt tcaaacatct
    10501 tttcagccaa ttcaggtcca ctaatattag cgtatcctgg gtaattttcg atatcagatg
    10561 tattattcat ctgaccacct ggcagaccac cttcaatcaa agctactttt agattgcttc
    10621 gagcagcata caaggccgca gtcatccctg caggtccagc accgataata atagtatcgt
    10681 acatatagat tccttctttc ttgttgtaac tatctttatt ctaactcttt cttgtcaatc
    10741 acgcaaggat tatgccttga aaacaagaat taaactcata accgcaaagg ataatactgg
    10801 gacaaccaag actccaatca taatcatatc atagagatgg gcttggcgag ccctggctgt
    10861 cttatcaact cccgacatgg ctctcagacc aatccaaatc cctaaaaaaa tcagaacaag
    10921 gatggtggtc aagatcaaac tctcgaaata taaagaaaat agttgcagta gcatgatttc
    10981 tctcatttct atctttttta aagagtaaac tcagctagtc caactaactg agttttcctt
    11041 tatctattat atcaaatata agtccgtttg taactagcga agaattcttt tgtccgctct
    11101 tctttagggg tgtggataat ctcatccgga gttccagact cgatgatttt ccccttatct
    11161 aagaagagaa ttttatccgc aacttgggct acaaaggaca tgtcatgact gaccaaaatc
    11221 atggtctgac ctgacttagc agcatctgca atagactttt ctacttcacc gaccaattct
    11281 gggtcaaggg ctgaagttgg ttcgtctaag agcaaaacat ctggtttcat agcaagcgca
    11341 cgcgctaggg caacccgttg cttctgtcca cctgataaat ggcgaggata atggttttca
    11401 cggtccgaaa gcccaacctt agccaactct tccttggcaa tcttagtcgc ttcttggtca
    11461 gataatttct tgacaacaac caagccttct ttcacattat caagtgctgt tcggcgttca
    11521 aacaaattaa actgttggaa aaccatagac aacttacgac gtagggcaag gatttcttct
    11581 tgagtgattt tagaaaaatc aactgaaaaa ccatcaatct gaatagagcc actgtcaggt
    11641 gtttcaagat aattgagact gcgaagaaag gttgattttc cagctcctga agaaccaatc
    11701 aaggctacaa cttccccttt ttgaatatcc aagtccagat gatccaagac agtctgtcct
    11761 gaaaaggatt tgcttaaatt cgaaatctta atcattaacg aaggtctcct ttcacatctg
    11821 tttgcactgt atcaggtgca gaaatagcca tttttctctc gatgaaacga ccgaggcttt
    11881 caattccgat attgactacc caataaacaa gggcaacgga gatgaagcgt tcaaaatagc
    11941 gataatcagc tccacctaga atctgagctt gggcaaagac ttccacaaca cccgcactaa
    12001 aagctagaga tgttcccttg gtcaaaccga tgagggaatt aatcaaggtt ggagtagcta
    12061 ccaccgctgc attaggaata atcactcgtc gataaacttg cgctcgggtc atacccagac
    12121 tgcgtgccgc ctcaatctca ccaggattaa ctgagagaat ggctgcacga atggtttcac
    12181 tagcataagc tgcctcatta aaggcaaagg cgacaatcgc aaaagctgca gctggaatcg
    12241 cattgatatt gagaccagtt ccccattgct gattgagggc tttcaaagcc aaagggattc
    12301 cgtagtaggt caacatgagt tgcaccaaaa tcggtgtccc ttttaagaaa ctaacaaaga
    12361 aggcctgcaa gggatataaa atcttgacac gattgatctt cacaatggca aaaagaagcg
    12421 ccaaaaccaa gccaaaaagg gcaccaccaa ttgtcaacat aattgttgtt ggaagttgtt
    12481 ggacaattct agggattcca tcaaagaccg aacgtaggct aaacagcttg ccatccggaa
    12541 tcaattgcat caagttttgg taccaatctg atgctaaaat cgttgtaaca ttcataaaaa
    12601 catcctcttc tgataatgat tcattctacc atgcttctgc cgtcaatgaa attatttgct
    12661 acggtcagat acagactttg tctacctact agtttatcat actttgaaac agggaagtta
    12721 tatattttat ctatcaaaga gatagataaa aactatttca gtcccagttc ctcataagat
    12781 tttcgataac cgatttgctt aacagttcca ttttctacta aaatgggccg ttttaacaac
    12841 ataccgtcac ttgctagcaa ctcagccgct tcttggtttg acaaacttcc taccttatct
    12901 tttagcccta attcacggta tttgatacca ctggtgttga aaaattgctt caattcaaat
    12961 cctgaggttt ctagccaatt caaaatgact tcttggctag gtgtttcttc cacgatatgg
    13021 acggctttat agtccacacc taattgattt aattcttgtt ttgctttttt acaagttgaa
    13081 catttggggt attcgataaa ttctaacatg tgcttctcct tctattgctt ctatctttaa
    13141 aatctactcc ttcatgctcc aagagccaag ctttcttttc cactcctgca gcataacctg
    13201 tcagacgctt gcctgctccc aacacacgat gacaaggtac taggatagac caaggattgc
    13261 gtcccactgc tccaccaatt gcttgagcag aagccacttg caggtcttga gcaatttgtc
    13321 cataggtcac tgtctgacca taaggaatgc cctgtaaata gtcccaaact ctcttttcaa
    13381 aattcgttcc gattggcgcc aagagcaagt tggataaatc ctgaggcttg cctttaaagt
    13441 aatcatctaa gcaagcaata actgggtcta aaataggatg actaacaact tcttctatcg
    13501 tttcatctcc tagtcccctc tcaaaatgct tctgctcctg aacccaaatt ccatacaaat
    13561 aatggtcatc agctacaagt gatagaatac caattggtga ggagtagagg atttttacat
    13621 acttcttttg cattatttct ttaatttttg ataggccaag cgttcgccat ctactggcat
    13681 cttaccgact tgtttaaaac caagtttttc aaaaatatgt tgcataacct tgttttcagc
    13741 atgcgtatct gagcgaaaat caagataatc aaaaccttca atcaagccct ctaagaaggt
    13801 ttgagcaact ccttttccct gcacatctgc tgccacagca atacggtgaa agactagata
    13861 ctctgactct ccagcttgcc agtttccctc ataaatagct tcataggcct cctctggact
    13921 cttggtcaca gcagcatagg ctagcagttc tccctcttcc aaggctacgt aggcttgccc
    13981 tgagatgata tcatcgataa taacatctgc atttggatag ccattttgcc actggtcact
    14041 accagcatct gctaaacatt ttttggcatc ctccatcacc tgcatgatgg catctacttc
    14101 atttggaaaa gctaaacgaa tttccatctt ttttcctcat ttctgactag tttctcccat
    14161 catagcataa tttaagtatt tctacaagca gttaaaactt gactttgtgt ttttgttatt
    14221 ttataatcta gttatcaaaa ctatataaaa aggagttaaa aatgaaaact accttttcct
    14281 acccaaaatg ggcagaaatt ccaaacattg acctctatct ggaccaggtt ttgctctatg
    14341 tcaatcaggt ctgcgcccct atctctccta ataaagacaa gggcctaaca gcatctatgg
    14401 tcaacaatta tgtgaaaaat ggttacctga caaagcctga caaaaaaaaa taccaacgcc
    14461 aacagattgc ccgtttgatt gctatcacaa ccctcaagtc tgtattttct attcaagaaa
    14521 tagcccagac acttaatact ctacaaactc aagcaagttc agaccaactc tacgatgctt
    14581 ttgtggacta catgaaccaa ggaattgacc cagctaaccc tattatccaa accagctgcc
    14641 aaaccgttaa actctatcat caaactctag acttaatcga tcatactcaa gaggaggtaa
    14701 tccaatgaac actagtctta aactcagcaa acaactcagt tttggagagg agattgctaa
    14761 tagcgtgacc catgctgtgg gtgcagtcat catgcttatc ttgctgccta tttcatccat
    14821 ctatagttat gaagcacacg gatttttatc ctctatcggc gtttccattt tcgtcatcag
    14881 tctctttctc atgttcctat catccaccat ttatcactct atggcctatg gttcgaccca
    14941 caaatatgtt ttgcgaatca ttgaccattc tatgatttac gttgccattg ccggctcata
    15001 cacgcccgtt gtcttgacct tgatgaataa ctggtttggc tatctgatta ttgtcatcca
    15061 atggggaacg accatctttg gtattctcta taaaatcttt gctaaaaagg tcaatgagaa
    15121 atttagcctt gctctttacc tgattatggg ctggttggtt ctggctatca ttcctgccat
    15181 tatcagtcaa acgacacccg ttttctggag tctcatggta actggcggac tctgttatac
    15241 agttggagct ggattttatg ccaagaaaaa accttatttc cacatgattt ggcatctctt
    15301 tatcctagct gcgtccgcac ttcaatacat cgctattgtt tattacatgt aaaaaagttg
    15361 agaaattcaa tctcaacttt ttt
//
LOCUS       DAVFER010000049        15220 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1105170250
            SAMEA2167659-rid19724873.denovo.049, whole genome shotgun sequence.
ACCESSION   DAVFER010000049 DAVFER010000000
VERSION     DAVFER010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2167659
            Sequence Read Archive: ERR388902
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 15220)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15220)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928716.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928716.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 04:07:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,118
            CDSs (total)                      :: 2,073
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 120
            CDSs (without protein)            :: 120
            Pseudo Genes (ambiguous residues) :: 0 of 120
            Pseudo Genes (frameshifted)       :: 67 of 120
            Pseudo Genes (incomplete)         :: 47 of 120
            Pseudo Genes (internal stop)      :: 34 of 120
            Pseudo Genes (multiple problems)  :: 23 of 120
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15220
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2167659-rid19724873.denovo.049"
                     /strain="1105170250"
                     /db_xref="taxon:1313"
     gene            complement(90..1661)
                     /gene="ffh"
                     /locus_tag="VU534_001732"
     CDS             complement(90..1661)
                     /gene="ffh"
                     /locus_tag="VU534_001732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HEU1514283.1"
                     /translation="MAFESLTERLQNVFKNLRKKGKISESDVQEATKEIRLALLEADV
                     ALPVVKDFIKKVRERAVGHEVIDTLNPAQQIIKIVDEELTAVLGSDTAEIIKSPKIPT
                     IIMMVGLQGAGKTTFAGKLANKLKKEENARPLMIAADIYRPAAIDQLKTLGQQIDVPV
                     FALGTEVPAVEIVRQGLEQAQTNHNDYVLIDTAGRLQIDELLMNELRDVKALAQPNEI
                     LLVVDAMIGQEAANVAREFNAQLEVTGVILTKIDGDTRGGAALSVRHITGKPIKFTGT
                     GEKITDIETFHPDRMSSRILGMGDMLTLIEKASQEYDEQKALEMAEKMRENTFDFNDF
                     IDQLDQVQNMGPMEDLLKMIPGMANNPALQNMKVDERQIARKRAIVSSMTPEERENPD
                     LLNPSRRRRIAAGSGNTFVEVNKFIKDFNQAKQLMQGVMSGDMNKMMKQMGINPNNLP
                     KNMPNMGGMDMSALEGMMGQGGMPDLSALGGAGMPDMSQMFGGGLKGKIGEFAMKQSM
                     KRMANKMKKAKKKRK"
     gene            complement(1673..2005)
                     /locus_tag="VU534_001733"
     CDS             complement(1673..2005)
                     /locus_tag="VU534_001733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009660419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HEU1514284.1"
                     /translation="MEIEKTNRMNALFEFYAALLTDKQMNYIELYYADDYSLAEIAEE
                     FGVSRQAVYDNIKRTEKILEDYEMKLHMYSDYIVRSQIFDQILERYPKDDFLQEQIEI
                     LTSIDNRE"
     gene            complement(2096..2473)
                     /locus_tag="VU534_001734"
     CDS             complement(2096..2473)
                     /locus_tag="VU534_001734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HEU1514285.1"
                     /translation="MKIRMRNTIQFDEQLEVIDQLYDVEVHEKGDYSYLLFYNEEKEK
                     VVIKFHGQELVMSRFSNPKTIMRFLKDSDSLAYIPTPMGMQEFIIQTSHYQVDRQKIE
                     LDYQLQNQEGHPFASYQLEITWG"
     gene            2545..3849
                     /locus_tag="VU534_001735"
     CDS             2545..3849
                     /locus_tag="VU534_001735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HEU1514286.1"
                     /translation="MNEKVFRDPVHNYIHVNNQIIYDLINTKEFQRLRRIKQLGTSSY
                     TFHGGEHSRFSHCLGVYEIARRITEIFEEKYPEEWNPAESLLTMTAALLHDLGHSAYS
                     HTFEHLFDTDHEAITQEIIQNPETEIHQVLLQVAPDFPEKVASVIDHTYPNKQVVQLI
                     SSQIDADRMDYLLRDSYFTGASYGEFDLTRILRVIRPIENGIAFQRNGMHAIEDYVLS
                     RYQMYMQVYFHPATRAMEVLLQNLLKRAKELYPEDKDFFARTSPHLLPFFEKNVTLTD
                     YLALDDGVMNTYFQLWMTSPDKILADLSHRFVNRKVFKSITFSQEDQDQLTSMRKLVE
                     DIGFDPDYYTAIHKNFDLPYDIYRPESENPRTQIEILQKNGELAELSSLSPIVQSLAG
                     SRHGDNRFYFPKEMLDQNSIFASITQQFLHLIENDHFTPNKN"
     gene            3862..4668
                     /gene="yidA"
                     /locus_tag="VU534_001736"
     CDS             3862..4668
                     /gene="yidA"
                     /locus_tag="VU534_001736"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000023490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HEU1514287.1"
                     /translation="MSIKLIAVDIDGTLVNSQKEITPEVFSAIQDAKEAGVKVVIATG
                     RPIAGVAKLLDDLQLRDEGDYVVTFNGALVQETATGHEIISESLTYEDYLDMEFLSRK
                     LGVHMHAITKDGIYTANRNIGKYTVHESTLVSMPIFYRTPEEMAGKEIVKCMFIDEPE
                     ILDAAIEKIPAEFYERYSINKSAPFYLELLKKNVDKGSAITHLAEKLGLTKDETMAIG
                     DEENDRAMLEVVGNPVVMENGNPEIKKIAKYITKTNDESGVAHAIRTWVL"
     gene            4711..5709
                     /locus_tag="VU534_001737"
     CDS             4711..5709
                     /locus_tag="VU534_001737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001008999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAP domain-containing protein"
                     /protein_id="HEU1514288.1"
                     /translation="MNFFSKLFNLKQNNHNRDTNSDCNNFYLNELECGLTPGQLILID
                     WTQKTGRNYNFPRYFKYSLQIDPESTHNQLYKLGYFTKNKTLSYLTVVELKTILSKHN
                     LATSGKKAELITRIINNVNIDNLDIPFEFKLTKEAQNLIIEHSDYIKAYYDKDITMED
                     YCKEKNNISFKATFGDIKWSLLNKQAHRNTVSGDFGCLSNTRKAQGRHLEQEGNIKHA
                     LIYYIESLIITISGLENNFSATDYPVYYPDSIPDYSLKHIQTLMESLSDDDYDFAFDE
                     ALFRFSILNANHFLSKEDIDYLRVNLPRSTAEEINNYLKKYECYSPLNNLELDDFE"
     gene            complement(5876..5947)
                     /locus_tag="VU534_001738"
     tRNA            complement(5876..5947)
                     /locus_tag="VU534_001738"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(5912..5914),aa:Arg,seq:cct)
     gene            complement(5990..6337)
                     /gene="rplS"
                     /locus_tag="VU534_001739"
     CDS             complement(5990..6337)
                     /gene="rplS"
                     /locus_tag="VU534_001739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HEU1514289.1"
                     /translation="MNPLIQSLTEGQLRTDIPSFRPGDTVRVHAKVVEGNRERIQIFE
                     GVVIARKGAGISENYTVRKISNGVGVERIFPIHTPRVEKIEVVRYGKVRRAKLYYLRA
                     LQGKAARIKEIRR"
     gene            complement(6456..6785)
                     /gene="crcB"
                     /locus_tag="VU534_001740"
     CDS             complement(6456..6785)
                     /gene="crcB"
                     /locus_tag="VU534_001740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000237393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HEU1514290.1"
                     /translation="MVIVYLAIACGLGALVRYFFSRYNQASKLPLGTLIANLLGCFLI
                     GVFYNHVESKEVYAILATGFCGGLTTFSTLNDELQRLLSDKKVFYSYLTLTYIGGLVA
                     IFLGILL"
     gene            complement(6779..7153)
                     /gene="crcB"
                     /locus_tag="VU534_001741"
     CDS             complement(6779..7153)
                     /gene="crcB"
                     /locus_tag="VU534_001741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HEU1514291.1"
                     /translation="MKKEQFYPLGIFLAAMLGGLVRYLVSTWLPASPDFPWGTLFVNY
                     LGIFCLIYLVKGYLVYKGTSKGLILALGTGFCGGLTTFSSLMLDTVKLLDTGRYLSLI
                     LYLLLSIGGGLLLAYYLGRKKW"
     gene            complement(7150..7416)
                     /locus_tag="VU534_001742"
     CDS             complement(7150..7416)
                     /locus_tag="VU534_001742"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HEU1514292.1"
                     /translation="MDLDIIRQEIDQIDDQIVKLLEERMHLVEGVVAYKKASGKPILD
                     TKREEVIFEKVRSRVEDKRYQETIVATFSDILKRSRDYQDQNIK"
     gene            complement(7532..7975)
                     /locus_tag="VU534_001743"
     CDS             complement(7532..7975)
                     /locus_tag="VU534_001743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HEU1514293.1"
                     /translation="MALAKIVFASMTGNTEEIADIVADKLRDLGLDVDVDECTTVDAS
                     DFLEADIAIVATYTYGDGELPDEMMDFYEDLADLNLNGKIYGVVGSGDTFYDEFCKAV
                     DDFDRVFVSTGAEKGSECVKVDLSAEEEDIERLEQFAEELAAKVG"
     gene            8079..9014
                     /locus_tag="VU534_001744"
     CDS             8079..9014
                     /locus_tag="VU534_001744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HEU1514294.1"
                     /translation="MEICQQILEKIKEYDTIIIHRHMKPDPDALGSQVGLKALLEHHF
                     PEKTIKAVGFDEPTLTWMAEMDLVEDRAYQGALVIVCDTANTARIDDKRYSQGDFLIK
                     IDHHPNDDVYGDLSWVDTSSSSASEMITLFAQTTQLALADRDAELLFAGIVGDTGRFL
                     YPSTTARTLRLAAYLREHNFDFAALTRKMDTMSYKIAKLQGYIYDHLEVDENGAARVI
                     LSQKILKQYNITDAETAAIVGAPGRIDRVSLWGIFVEQADGHYRVRLRSKVHPINEIA
                     KEHDGGGHPLASGANSYSLEENEIIYQKLKNLLKN"
     gene            9068..9352
                     /locus_tag="VU534_001745"
     CDS             9068..9352
                     /locus_tag="VU534_001745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HEU1514295.1"
                     /translation="MARKETMAERKYCKMKKDIHPEYRPVVFMDTTTGYQFLSGSTKR
                     SNETVEFEGETYPLIRVEISSDSHPFYTGRQKFTQADGRVDRFNKKYGLK"
     gene            complement(9409..9627)
                     /locus_tag="VU534_001746"
     CDS             complement(9409..9627)
                     /locus_tag="VU534_001746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000028153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1514296.1"
                     /translation="MSISPRFETLEQAIASKDLEKVREAFKKMNSTWTINESVVRDNS
                     IAHYGRVETAISFLPSSMEIEPTDESGT"
     gene            complement(9624..10375)
                     /locus_tag="VU534_001747"
                     /pseudo
     CDS             complement(9624..10375)
                     /locus_tag="VU534_001747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            10712..12058
                     /gene="gdhA"
                     /locus_tag="VU534_001748"
     CDS             10712..12058
                     /gene="gdhA"
                     /locus_tag="VU534_001748"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HEU1514297.1"
                     /translation="MTSAKEYIQSVFETVKARNGHEAEFLQAVEEFFNTLEPVFEKHP
                     EYIEENILARITEPERVVSFRVPWVDRDGKIQVNRGYRVQFNSAVGPYKGGLRFHPTV
                     NQGILKFLGFEQIFKNVLTGLPIGGGKGGSDFDPKGKTDAEVMRFCQSFMTELQKHIG
                     PSLDVPAGDIGVGGREIGYLYGQYKRLNQFDAGVLTGKPLGFGGSLIRPEATGYGLVY
                     YTEEMLKANGNSFAGKKVVISGSGNVAQYALQKATELGATVISVSDSNGYVIDENGID
                     FDLLVDVKEKRRARLTEYAAEKATATYHEGTVWTYAGNYDIALPCATQNEINGEAAKR
                     LVAQGVICVSEGANMPSDLDAIKVYKENGIFYGPAKAANAGGVAVSALEMSQNSLRLS
                     WTREEVDGRLKDIMTNIFNTAKTTSETYGLDKDYLAGANIAAFENVANAMIAQGIV"
     gene            complement(12564..12734)
                     /locus_tag="VU534_001749"
     CDS             complement(12564..12734)
                     /locus_tag="VU534_001749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1514298.1"
                     /translation="MKKENEYVILTTASLGVMIGIVFAIFLDFPVEYGISLGLLNGIV
                     LGSLIVYKNNKN"
     gene            complement(12747..13325)
                     /locus_tag="VU534_001750"
                     /pseudo
     CDS             complement(12747..13325)
                     /locus_tag="VU534_001750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151458.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
     gene            complement(13342..14145)
                     /locus_tag="VU534_001751"
                     /pseudo
     CDS             complement(13342..14145)
                     /locus_tag="VU534_001751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
     gene            complement(14238..14396)
                     /locus_tag="VU534_001752"
     CDS             complement(14238..14396)
                     /locus_tag="VU534_001752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase domain-containing protein"
                     /protein_id="HEU1514299.1"
                     /translation="MSLLETAKRHQLNSEKYLSYLLECLPNEETLVNKEVLEAYLPWT
                     KVVQEKCK"
     gene            complement(14467..14896)
                     /locus_tag="VU534_001753"
                     /pseudo
     CDS             complement(14467..14896)
                     /locus_tag="VU534_001753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014295150.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(14991..15203)
                     /locus_tag="VU534_001754"
     CDS             complement(14991..15203)
                     /locus_tag="VU534_001754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001815725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU1514300.1"
                     /translation="MTQPLLHADETSYRVLESDSQLTYYWTFLSGKAEKQGITLYHHD
                     QCRSGSVVQEFLGDYSGYVHCDILRQ"
BASE COUNT         4659 a         3247 c         2651 g         4663 t
ORIGIN      
        1 gatattctaa aaccttgata ctgtacgttt tatcatagaa atttttactt tattttctca
       61 tcaaatgaga tttgcatcaa tctcttgtct tacttgcgtt tcttcttcgc tttcttcatt
      121 ttgttagcca tacgtttcat ggactgtttc atggcaaatt caccaatttt acctttcaaa
      181 ccgccaccaa acatctggct catatctggc attcctgctc ctccgagagc tgataagtca
      241 ggcataccgc cttgtcccat cattccttca agggcagaca tatccattcc tcccatattt
      301 ggcatatttt taggaaggtt atttggatta atccccattt gcttcatcat tttattcata
      361 tccccagaca taacaccctg catgagctgt ttagcctggt taaagtcctt gatgaattta
      421 ttgacttcga cgaatgtatt tccagaacca gcagcaatac gacggcgacg gcttggattt
      481 aacaaatctg ggttttcacg ctcttcaggt gtcatcgaag acacaatggc acgtttacga
      541 gcaatctggc gttcatccac cttcatgttt tgaagggctg gattgttggc catacctgga
      601 atcatcttga gcaagtcttc catcggcccc atattttgca cctgatctaa ttgatcgatg
      661 aaatcattaa aatcaaaggt gttttcgcgc atcttctcag ccatttcaag ggctttttgt
      721 tcatcgtatt cctgagaagc tttctcaatc aaagtgagca tatcccccat accaaggata
      781 cggctagaca tgcggtctgg gtggaaggtt tcaatgtccg taatcttttc acctgtacca
      841 gtgaacttga ttggttttcc agtaatgtga cgaacagaca gagcagcacc accacgagta
      901 tcgccatcaa tcttggtaag gatgacccca gtcacttcca actgagcatt aaactcacgc
      961 gcaacattgg ctgcttcctg accaatcata gcatcaacga caagcaagat ttcatttggt
     1021 tgagccaatg ctttcacatc acgaagctca ttcatgagga gctcatcaat ctgcaaacga
     1081 cccgcagtat caatcaagac atagtcgtta tgattagttt gggcttgctc caaaccttga
     1141 cgtacaatct caacagctgg tacttctgtt ccaagtgcaa agacaggcac atcaatctgt
     1201 tgtcccaagg tcttaagctg gtcaatggca gctggacgat aaatatccgc cgcaatcatc
     1261 aaaggacgag cattttcttc tttcttgagt ttgttggcca atttaccagc aaaggttgtt
     1321 ttaccagccc cttgtaaacc aaccatcatg atgatggttg gaatcttagg tgacttgata
     1381 atttctgccg tatcagaacc taaaacggct gtcaattcct catcaacgat tttaataatc
     1441 tgttgcgcag gattaagtgt atcaatgacc tcatgcccga ctgcacgctc acgaactttc
     1501 ttgataaagt cctttacaac aggcaaggca acgtcggcct cgagcaaggc caagcgaatt
     1561 tctttggttg cctcttggac atcagattca gagatttttc cttttttacg tagattttta
     1621 aagacgttct gcaaacgttc tgttaaactt tcaaatgcca tttttcttcc tcttattctc
     1681 tattatcaat gcttgttaaa atttctatct gctcctgcag aaagtcatcc ttgggatagc
     1741 gctccaaaat ctgatcaaaa atctgactgc ggacaatata gtccgagtac atgtgcaatt
     1801 tcatctcata atcttccaga atcttttctg ttcgcttgat attgtcatag acagcctgac
     1861 gactgacacc gaactcctcg gcaatttcag caaggctgta atcatcagcg tagtagagct
     1921 cgatataatt catttgctta tctgtcaaaa gcgccgcata aaattcaaag agcgcattca
     1981 tacgattggt tttttcgatt tccataactt ttattatacc aaaaattagc ctaatctacc
     2041 acactaggaa gccgatccaa gaagatagat agctaaattt gaaaaagaca tgagcctagc
     2101 cccaagtaat ttccaattga tagctggcaa agggatgtcc ctcttgattt tgtagttgat
     2161 aatctagttc aatcttttgc ctatcaactt gataatggct cgtttggatg ataaactcct
     2221 gcatgcccat aggtgtagga atataggcta aactatcgct atcctttaga aagcgcataa
     2281 tggtcttggg attagaaaat cggctcatca caagttcttg accatgaaat ttaatcacta
     2341 ctttttcctt ttcctcatta tagaaaagca ggtagctata atctcctttt tcatgcactt
     2401 ccacatcata aagctggtca atcacttcca actgctcatc aaactgaatc gtatttcgca
     2461 tccgaatctt cacatcaggc cctctttctt gtctcttgtc ctactatttt accaaaaaga
     2521 gcaggatttt gctataatgg tcatatgaac gaaaaagtat tccgtgaccc tgttcacaac
     2581 tacatccatg tcaataatca aatcatctat gacttgatta atacaaaaga atttcagcgt
     2641 ttgcgccgga tcaaacaact gggaacttcc agttatacct tccacggtgg agaacacagt
     2701 cgcttctctc actgtctagg agtctatgaa attgcacgac gcatcacaga gattttcgaa
     2761 gaaaaatatc ctgaggaatg gaatcctgcc gagtctctct tgaccatgac cgctgctctc
     2821 ctacacgacc ttgggcatag tgcctactcc catacttttg aacatctctt tgatacagac
     2881 catgaagcca ttactcagga gattattcaa aatcctgaga cagagattca ccaagtcctg
     2941 ctacaagtgg cacctgattt cccagaaaag gtggccagtg tcattgacca tacctatcct
     3001 aataagcagg tcgtgcagct catttctagt cagattgacg cagatcgcat ggactatctc
     3061 ttgcgcgact cctattttac aggagcatcc tatggggaat ttgacctgac tcgaatcctc
     3121 cgagtcattc gtcctatcga aaatggtatc gcctttcagc gcaatggcat gcacgccatc
     3181 gaagactacg tcctcagtcg ctaccagatg tacatgcagg tttatttcca ccccgcaaca
     3241 cgcgccatgg aagttctcct acagaatctt ctcaaacgcg ccaaggaact ctatcctgag
     3301 gacaaggatt tctttgcccg aacttctcca cacctcctgc ctttcttcga aaaaaatgtg
     3361 accttgactg actatctggc tctggatgat ggcgtgatga atacctactt ccagctttgg
     3421 atgaccagtc ctgacaagat tcttgcagat ttatcgcatc gctttgtcaa ccgcaaggtc
     3481 tttaaatcca ttaccttttc acaagaggac caagatcaac ttactagcat gagaaaattg
     3541 gttgaggata tcggctttga tcccgactac tacactgcca ttcataagaa ctttgacctc
     3601 ccttatgata tctatcgtcc cgaatctgaa aacccacgga cacagattga gattttacaa
     3661 aaaaatggag aactggccga actctctagc ctgtctccta tcgtccaatc ccttgctggc
     3721 agtcgccacg gagataatcg cttttatttt ccaaaagaaa tgttggacca aaacagcatc
     3781 tttgcaagca ttacccagca atttttacac ttgattgaga acgatcattt taccccaaat
     3841 aaaaactaga agaggaaatt tatgagtatt aaactaattg ccgttgatat cgacggaacc
     3901 cttgtcaaca gccaaaagga aatcactcct gaagtttttt ctgccatcca agatgccaaa
     3961 gaagctggtg tcaaagtcgt gattgcaact ggccgcccta tcgcaggcgt tgccaaactt
     4021 ctagacgact tgcagttgag agacgagggg gactatgtgg taaccttcaa cggtgccctt
     4081 gtccaagaaa ctgctacagg acatgagatt atcagcgaat ccttgactta tgaggattat
     4141 ctagatatgg aattcctcag tcgcaagctc ggtgtccaca tgcatgccat taccaaggac
     4201 ggtatctata ctgcaaatcg caatatcgga aaatacactg tacacgaatc aaccctcgtc
     4261 agcatgccta tcttctaccg tacccctgaa gaaatggctg gcaaagaaat tgttaaatgt
     4321 atgtttatcg atgaaccaga aattctcgat gctgcgattg aaaaaattcc agcagaattt
     4381 tacgagcgct actccatcaa caaatctgct cctttctacc tcgaactcct taaaaagaat
     4441 gtagacaagg gttcagccat tactcacttg gctgaaaaac tcggattgac caaagatgaa
     4501 accatggcaa tcggtgatga agaaaatgac cgtgccatgc tggaagtcgt tggaaacccc
     4561 gttgtcatgg aaaatggaaa tccagaaatc aaaaaaatcg ccaaatacat caccaaaaca
     4621 aatgacgaat ccggcgttgc ccatgccatc cgaacatggg tactgtaaaa gtatcatttt
     4681 tcaataagaa ttgattagca ataaaatcca atgaattttt ttagcaaact atttaattta
     4741 aaacaaaata atcataatag agacacaaat tctgattgta acaattttta cctaaacgaa
     4801 ttagaatgtg gccttactcc tgggcaactc atactcatag attggactca aaaaacaggg
     4861 agaaattata atttcccaag atattttaaa tactctcttc aaattgaccc tgaatctaca
     4921 cacaatcaat tatacaaatt aggatacttc actaaaaata agactttatc atatcttaca
     4981 gtagtagaat taaaaactat attatctaaa cataatttag ctacttctgg aaaaaaagca
     5041 gaattaatta caagaataat taataatgtt aacattgaca atttagatat tccgttcgaa
     5101 tttaaactaa caaaagaagc acaaaatctt attatcgaac atagtgacta tatcaaagca
     5161 tactatgata aagacataac tatggaagat tattgtaaag aaaaaaacaa tatctctttt
     5221 aaagcaactt ttggtgatat aaaatggagt ctcttaaata aacaagctca taggaatact
     5281 gtatcaggag attttggatg cttatctaac acacgaaagg ctcagggaag acatttggaa
     5341 caagaaggta atattaaaca tgctttaata tattacatag aatctttgat aattactatt
     5401 tcaggattag aaaacaattt ttcagccact gattatccag tatattatcc cgattcgata
     5461 cctgactact cactaaaaca tattcaaaca ttaatggaat cattatctga tgacgattat
     5521 gattttgctt ttgatgaagc attatttcgc ttctcaattt tgaatgcaaa tcatttttta
     5581 tctaaggaag atattgacta tttaagagtt aatttacctc gttccactgc tgaagaaata
     5641 aacaattact taaagaaata tgaatgttat agtcctttaa ataatttaga acttgacgat
     5701 tttgaataaa ttgactatac aaacatttat atactcgata tagtctcaat tttatctgat
     5761 gattgcccaa atttttcaat aataaaacgc ataatattat ggagacaatc ccctatatta
     5821 tgcgttcttt taatatcaaa gactttttga caaacttctt tgatatctaa ttacatgccc
     5881 cctgcaggaa tcgaacctgc aactactcct taggagggag ttgttatatc cattgaacta
     5941 agggagctag ataaaaactc tgctaaatga gcagagtttt ttagtcgaat taacgacgga
     6001 tttctttgat acgagctgct ttaccttgaa gagcacgcaa gtagtacaat ttcgcacgac
     6061 gtactttacc gtaacgaaca acttcgattt tttcaacacg tggagtgtgg attgggaaga
     6121 tacgctcaac acctacaccg ttagagattt tacgaactgt gtagttttct gagattccag
     6181 cacctttacg tgcgataaca acaccttcaa aaatctggat acgttcacgg ttaccttcga
     6241 caactttcgc atgtacacga acagtgtcac caggacggaa tgatgggata tctgtacgaa
     6301 gttgaccttc agtcaagctt tggattaatg gattcatttt attctcctat ctttgtcaat
     6361 cttgaggaat cttcctcagc ggataaactg tatttttgtg cgtccattac acacaagata
     6421 tagtttacca aatttctaaa aaaaagtaaa gaaatttata gcaaaattcc taaaaaaatc
     6481 gcaaccaaac cacctatgta agtcaaagtc aggtaagaat aaaagacctt cttatcactt
     6541 agcagtcttt gaagttcgtc attcaaggtc gaaaaagttg ttaaaccgcc acaaaatcct
     6601 gttgctagaa tagcatatac ttccttagac tctacatgat tgtagaatac tccaattaaa
     6661 aaacaaccta aaagattagc tatgagcgtt ccgagtggca atttagaagc ttgattatag
     6721 cgagaaaaga aataccgtac gagtgctccc aagccacagg cgattgcaag atagacgatt
     6781 accatttctt cctccccaaa tagtaagcta aaagcaggcc tccaccgata ctcaaaagca
     6841 aatacagtat caaactaaga taacgccctg tatcaagcag cttcacagta tcaagcatta
     6901 ggctggaaaa agttgttaaa cctccgcaaa aacccgtccc cagtgctaaa atcaagccct
     6961 tactagtccc cttatagacc agatagccct tgacaagata aatcaagcag aaaattccca
     7021 gatagttgac aaagagagtg ccccaaggga aatctggact ggctggtaac caggtggaaa
     7081 ctagatatcg gacaagtccg cccaacatag cagctagaaa aattcctagc ggataaaatt
     7141 gttctttttt catttgatat tttgatcctg ataatcacgc gaacgtttga gtatgtccga
     7201 aaaagtcgcg acaatagtct cctgatagcg cttgtcctct acacgactcc taaccttttc
     7261 aaaaataact tcttctctct tagtatctaa aatcggttta cctgaagctt tcttataagc
     7321 aaccaccccc tcaactaaat gcattcgttc ttctaacagt ttgacaattt ggtcgtcgat
     7381 ttgatcgatt tcttgacgaa taatatctaa atccatacag tctcctcctt tatttgaatt
     7441 attgtatcaa aaagccatca attaggctag taaaatccca actctcgata agaaaaatgc
     7501 actgattgat tacatcagcg cacttttatg tttatcctac tttagcagcc aattcttctg
     7561 cgaattgttc caagcgttca atatcttctt cctcggcaga aagatcaact ttaacacact
     7621 ctgaaccttt ttctgctcct gttgacacaa agacacggtc aaagtcatca acagccttac
     7681 agaattcatc gtagaaggta tctcctgagc cgaccactcc gtagattttg ccattcaagt
     7741 tgagatctgc taggtcttcg tagaagtcca tcatctcatc tggcaattca ccatcaccat
     7801 aagtataggt cgcaacgata gcgatgtctg cttccaagaa gtctgaagcg tcaacagttg
     7861 tacattcatc aacatcaaca tccaagccca agtcacgtaa tttgtctgct acaatatctg
     7921 caatttcttc ggtattaccg gtcatactgg caaatacaat ttttgctaat gccatatcgt
     7981 cctcctcaat ttatctttct ccattatatc acatcttttt cattttaaaa ataaaaattc
     8041 ttgtgctaca atgaaatgag aaagaattga ggttatttat ggagatttgc caacaaattt
     8101 tagaaaaaat taaagaatac gacaccatta tcattcatcg tcatatgaaa ccagaccctg
     8161 atgccttggg aagtcaggtg ggattgaaag ccttgctgga acatcatttc ccagaaaaaa
     8221 ccatcaaagc cgtcggtttt gatgaaccaa ctcttacttg gatggctgag atggatcttg
     8281 ttgaagatag agcctaccaa ggcgcacttg tcatcgtctg tgatacagct aatactgctc
     8341 gtatcgatga taagcgctat agtcaaggtg attttctcat taagattgac caccatccaa
     8401 atgatgatgt atacggtgac ctgtcttggg tcgatactag ttcaagtagc gctagcgaga
     8461 tgattaccct atttgcccaa acaacccaac tagccttggc agatcgcgat gctgagttgc
     8521 tctttgcagg aattgtcggt gatacaggtc gcttcctcta cccttctacc actgcacgga
     8581 ctcttcgcct ggctgcttat ttgagagaac ataactttga ctttgcggct ctcactcgca
     8641 aaatggacac tatgagctac aaaattgcta aactgcaagg ctacatctac gaccatctgg
     8701 aagtggatga aaatggtgct gctcgcgtta tcctgagtca gaaaatcttg aaacaataca
     8761 atataaccga tgctgaaact gcggccattg taggtgcacc tggacgcatt gacagagtga
     8821 gtctctgggg aatttttgtc gaacaggctg atggccacta ccgagttcgc ttacgcagta
     8881 aagtccatcc tatcaatgaa attgccaagg agcatgatgg tggaggccac cctctagcaa
     8941 gtggtgctaa ttcctatagc ctagaagaaa acgaaatcat ctaccaaaag ttaaaaaact
     9001 tgcttaaaaa ctgataaaat acttgccaaa cttttcagaa tctgatagac tagtatagta
     9061 acaatctatg gctcgcaaag agaccatggc agaaaggaaa tattgcaaaa tgaaaaaaga
     9121 tatccatcca gaatatcgcc cagttgtctt catggacaca actactggtt accaattcct
     9181 tagcggttca acaaaacgct ctaacgaaac agttgagttc gaaggcgaaa cttacccatt
     9241 gatccgtgtg gaaatttcat cagactcaca cccattctac actggacgtc aaaagttcac
     9301 tcaagcagat ggacgcgtgg atcgtttcaa caaaaaatac ggtctcaaat aatgataaga
     9361 gaacagtttt ggctgttctt ttttgtttct tgaaatcaac tgctgttttc atgttccaga
     9421 ctcatctgta ggttcgattt ccatgctact aggcaggaag gaaatagctg tttcaacacg
     9481 tccataatga gctatactat tgtcacgaac cacactttca ttgatggtcc aagtggaatt
     9541 cattttctta aaagcttctc ggactttttc caaatctttg gaggcaatgg cctgctctaa
     9601 ggtttcaaaa cgaggactta tactcatctg ctttcaaaaa gcattctagt ccatctccga
     9661 ttaccgatgg actttatcac ctccttctcc agtccttgta tgacatcttg aagttgattc
     9721 atgacatctt ccaaagttcg aaaggcttta ttcttaaatc cacgtttacg aatctctttc
     9781 cacacttgtt caatgggttc atctctggtg tgtatggagg aataaaggta aaatcaatat
     9841 tagtcggaat atttaaggta cttgatttat gccatatagc attgtccata acgagtaaaa
     9901 ggataagctt gtgaaagctc ttctaaaaag gcgttcatcc acactccttt ttataaacct
     9961 gaaataaggc atcaattgta acaaattctc ctgcctctgt agccttcaaa tgacgggcaa
    10021 gaaaggcttt ctcttcctca actgtcatat atgcatggtt acgaccacca cgtgtttctt
    10081 gaaggagaga gtcgagtccg aactcctcat atttttttac gtttcgccaa atcgttgttt
    10141 gattacagtc taaaagctct ataatctctt tataagattt gcccatcaga cgaaatatag
    10201 tagattgaaa ctagaatagt acacctctac ttctaaaaca ttgttagaaa tcgatttgtc
    10261 ctgttcttgt ttcattttac tatagaacga tttgaaggcg tttataatat ttagctgtac
    10321 gagagtcttt taaaagtgtt ttgatggttt ggatttcttc tttagttgat ttcatattac
    10381 tattatataa tgctttttga ttttagtctg gtataaatat tgctttcctc caaaatggtc
    10441 atagttttac tggcaaatct aacatatcac ggataaatta acaagtgatt tctgaattgc
    10501 taaacatttt cttttcttat agcatacttt aagattttgt ctttgagaaa gatatttcca
    10561 agaaaaacgt tcgttttttt atctattttc aaaaaaacca aaaaactgaa ttgaaagaat
    10621 ttttagaaaa tttctgtttt ttctttacag tgaaaaaaaa ttctgctata atgtcttatg
    10681 taataaaata tgacaataaa aggagaacga tatgacatct gctaaagaat atatccaaag
    10741 cgtgtttgaa actgtgaaag ctcgtaacgg gcacgaggct gaattcctcc aagctgttga
    10801 agaatttttc aacactttag aacctgtatt tgaaaaacac cctgagtata tcgaagaaaa
    10861 tatcttggca cgtattactg agcctgagcg cgtggtttct ttccgtgttc cttgggttga
    10921 ccgtgatgga aaaattcaag taaaccgtgg ttaccgtgtt caattcaact cagctgttgg
    10981 accatacaaa ggtggacttc gtttccaccc aactgtaaac caagggatct tgaaattcct
    11041 cggatttgaa caaatcttta aaaatgtctt gactggactt cctatcggtg gaggtaaagg
    11101 tggatcagac ttcgatccta aaggtaaaac agatgctgaa gtgatgcgct tctgccaaag
    11161 cttcatgact gaattgcaaa aacacatcgg accatcactt gacgtacctg ctggtgatat
    11221 cggtgttggt ggacgtgaaa ttggttacct ttacggtcaa tacaaacgtc ttaaccaatt
    11281 tgatgctggt gtcttgactg gtaaacctct tggatttggt ggtagcttga ttcgtccaga
    11341 agcaactggt tacggtttgg tttactatac tgaagaaatg ctcaaagcta acggtaacag
    11401 ctttgctggt aagaaagtcg ttatttcagg ttctggtaac gttgctcaat atgctcttca
    11461 aaaagcaact gaactcggtg caactgttat ttctgtttct gactcaaatg gttatgtcat
    11521 cgatgaaaat ggtatcgact tcgatctttt ggttgatgtt aaagaaaaac gtcgtgctcg
    11581 tttgactgag tatgcagctg aaaaagcaac tgcaacctac cacgaaggta ctgtatggac
    11641 ttacgctgga aactatgaca ttgctcttcc atgtgccact caaaacgaaa tcaacggtga
    11701 agcagctaaa cgtttggttg ctcaaggcgt tatctgtgta tctgaaggtg ccaacatgcc
    11761 gagcgacctt gatgccatca aagtttacaa agaaaatggt atcttctacg gacctgcaaa
    11821 agctgccaac gctggtggtg tagccgtttc agctcttgaa atgagccaaa acagtcttcg
    11881 cctctcatgg actcgtgaag aagttgatgg ccgtctcaaa gacatcatga caaacatctt
    11941 caacacagct aaaacgactt cagaaacata cggtcttgat aaagactacc ttgcaggagc
    12001 taacattgct gcctttgaaa atgtagcaaa tgccatgatt gcacaaggta ttgtttaaga
    12061 tttatttact caatcctcaa tcactacgat tggggatttt tagcttgaat taaaaaattg
    12121 gaaaatctaa ttaaataaaa tgaaatgaaa taaaaactga acaaattgat tgcggaattc
    12181 aaaccaattt ctaacatatt tctagaaatt aatttgactt ttctaatcga tttgttcata
    12241 tcttatttca atttactata cttacttgac cctttttata ctcaatgaaa atcaaagagc
    12301 aaactaggaa gcgagccgca ggctgtactt gagtacggta aagcaaagct gacgtggttt
    12361 gaagagattt tcaaagagta ttaaacaaaa agaaaaaccg ctactcctaa gaatagcgat
    12421 ttaatcatgt ttttaagcta ctactgtagt tgctctatta tttaagtgtt atgaataact
    12481 tcaatatctt taaagctttt tgttagattt ataatttcaa ctatagccat ctctactcct
    12541 tagtttacag caaaaaatta tgcttaattc ttattgtttt tgtaaacaat cagcgaaccc
    12601 aatactattc cattcaacaa gcctaaagaa ataccatatt caactggaaa atctaaaaaa
    12661 attgcaaaca ctattccaat catcacccct agtgaggctg ttgttaaaat tacatattca
    12721 ttttctttct tcattttctt tacacctcat ttcctttttg tatataagct gtagtactct
    12781 ccaccaagat ccattaagta cttatgattt cctgactcaa caatcttacc acctttcatt
    12841 acaaaaataa catccgcatc cttaatcgtt gacaatctat gagctacaat tatttgagta
    12901 cagccctgac tttgtatata ctttgttatt ctttcctcat taatagtgtc taatgcacta
    12961 gttgcttcat ctaaaattac aatactagga ttatttatta atgcacgtgc cagtgctatc
    13021 cgttgccttt gcccacctga aatatttgac cccatctctg agatgatagt attaaatttc
    13081 atcggcatag ccatgatttc atcatagatt tgaactgctt tacaaacttc ctctatcttt
    13141 tgtgaagtaa cttcgtgctt taaagttata ttatcaagaa tacttcggtt caataaaaat
    13201 gaatcctgtg gaactactcc taaattttga cttaatattt ttttatctat ttgattaata
    13261 tttacaccat caaataaaac ttttcctgta tcaatcttat ataatcttga tggtattttt
    13321 gataatagac ttcctgcaaa actagaatcc tagttcatga ttgataatac cagcaatcaa
    13381 attcattcgt aatccgaagc gtttagatga tttcgatagg ttgttgaaat cattttaaac
    13441 gtttttactt tggcaaagat gttctcaacc ttgcttctct ccttagatag cgcatggtta
    13501 tagactttat cttcaattgt tagcggtttg agtttgctgg atttacgtga agtttgtgct
    13561 tgaggatata tcttcatgag cccttgataa ccactgtcag ccaagatttt accagcttgt
    13621 ctgatatttc tgcgactcat tttgaacaac ttcatatcat gacaatagtt cacagtgata
    13681 tccaaagaaa caattctccc ttgacttgtg acaatcgctt gagccttcat agcgtgaaat
    13741 ttctttttac cagaataatt cgctaattct ttttttaggg cgattgattt ttacttccgt
    13801 cgcatcaatc attaccgtgt cctcagaact gagaggagtt cttgaaatcg taacaccact
    13861 ttgaacaaga gttacttcaa cccattggct ccgacggatt aagttgcttt cgtgaatacc
    13921 aaaaacagcc gcaatttgtt cataagttcg atattctcgc acatattgaa gagtggccat
    13981 aagaaggtct tctagactta atttaggttt tcgtccacct tttgcgtgtt taagttgata
    14041 agctgttttt aatacagcta acatctcttc aaaagtcgtg cgttgaacac caacaagacg
    14101 cttaaatcgt gcatcggtta gttgtttact tgcttcatca ttcatagaac tattatacca
    14161 tattttgttt cgcaggaagt ctattgaaaa atctccagac tggagaactc acggatagtt
    14221 cctaatctgg agatttctta tttgcacttt tcttgtacaa ctttagtcca tggtaaataa
    14281 gcctctaaaa cctctttgtt tacgagagtt tcctcgtttg gaagacattc tagaagatag
    14341 gatagatatt tctcgctatt taattgatga cgtttagctg tttccaacaa actcataata
    14401 atagctcttg ctttagctcc ttcaaaactt tgagaaaata accaccctcg cttttttaaa
    14461 ctgagcttag gctaaaagag tccactggac tcttttactc cgtcccataa ccaatgattt
    14521 aatggcgcgt tcagctagat tattggaaag gaccagatgt ccgtctttca aaatggtctt
    14581 aaaggtttct tcatacttga ggctgtattc aattgccctt cctagttttg aacctgctaa
    14641 aactgactga cgccggcact aagcaaagaa gtcttccatt aagggctgga gatgttcttg
    14701 acgtttctgt agtcgttcat cagctggcaa agcctcccag tctctttcca aggaaaataa
    14761 ctgatcacaa taagctaaac ctttagctcc taaggatgat ttatccgctt gcttgggggg
    14821 gcgcttcaaa aaacttcctt ctcacatgcg cccaacatcc aacaagttca gcttcttcca
    14881 gttgacgata agcagacgag cggttcgaag tttaccaagc ttagcgtcgc cttgctccta
    14941 aaccttggac tgctatcgca taggcagaac tagaggacta aagtcctaag ttactgccgc
    15001 aaaatatcac aatgcacata gccagaataa tctcctagga attcttgtac tactgaacca
    15061 cttcgacact gatcatggtg gtaaagcgta atcccttgtt tctctgcttt acctgacaaa
    15121 aaagtccaat agtaagtcag ctgactatca ctctctagca ccctataaga agtttcatcc
    15181 gcatgaagta agggctgagt caatagtctc tctcgcaaga
//
LOCUS       DAVFER010000050        14816 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1105170250
            SAMEA2167659-rid19724873.denovo.050, whole genome shotgun sequence.
ACCESSION   DAVFER010000050 DAVFER010000000
VERSION     DAVFER010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2167659
            Sequence Read Archive: ERR388902
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14816)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14816)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928716.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928716.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 04:07:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,118
            CDSs (total)                      :: 2,073
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 120
            CDSs (without protein)            :: 120
            Pseudo Genes (ambiguous residues) :: 0 of 120
            Pseudo Genes (frameshifted)       :: 67 of 120
            Pseudo Genes (incomplete)         :: 47 of 120
            Pseudo Genes (internal stop)      :: 34 of 120
            Pseudo Genes (multiple problems)  :: 23 of 120
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14816
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2167659-rid19724873.denovo.050"
                     /strain="1105170250"
                     /db_xref="taxon:1313"
     gene            complement(63..1685)
                     /gene="groL"
                     /locus_tag="VU534_001755"
     CDS             complement(63..1685)
                     /gene="groL"
                     /locus_tag="VU534_001755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166362.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HEU1514301.1"
                     /translation="MSKEIKFSSDARSAMVRGVDILADTVKVTLGPKGRNVVLEKSFG
                     SPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVREG
                     IKNVTAGANPIGIRRGIETAVAAAVEALKNNAIPVANKEAIAQVAAVSSRSEKVGEYI
                     SEAMEKVGKDGVITIEESRGMETELEVVEGMQFDRGYLSQYMVTDSEKMVADLENPYI
                     LITDKKISNIQEILPLLESILQSNRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKA
                     PGFGDRRKAMLEDIAILTGGTVITEDLGLELKDATIEALGQAARVTVDKDSTVIVEGA
                     GNPEAISHRVAVIKSQIETTTSEFDREKLQERLAKLSGGVAVIKVGAATETELKEMKL
                     RIEDALNATRAAVEEGIVAGGGTALANVIPAVATLELTGDEATGRNIVLRALEEPVRQ
                     IAHNAGFEGSIVIDRLKNAELGIGFNAATGEWVNMIDQGIIDPVKVSRSALQNAASVA
                     SLILTTEAVVANKPEPVAPAPAMDPSMMGGMM"
     gene            complement(1701..1985)
                     /gene="groES"
                     /locus_tag="VU534_001756"
     CDS             complement(1701..1985)
                     /gene="groES"
                     /locus_tag="VU534_001756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HEU1514302.1"
                     /translation="MLKPLGDRVVLKIEEKEQTVGGFVLAGSAQEKTKTAQVVATGQG
                     VRTLNGDLVAPSVKTGDRVLVEAHAGLDVKDGDEKYIIVGEANILAIIEE"
     gene            complement(2141..2536)
                     /locus_tag="VU534_001757"
     CDS             complement(2141..2536)
                     /locus_tag="VU534_001757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000282444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HEU1514303.1"
                     /translation="MYNKVILIGRLTSTPELHKTNNDKSVARATIAVNRRYKDQNGER
                     EADFVNMVLWGRLAETLASYATKGSLISVDGELRTRRFEKNGQMNYVTEVLVTGFQLL
                     ESRAQRAMRENNAGQDLADLVLEEEELPF"
     gene            complement(2614..3375)
                     /locus_tag="VU534_001758"
     CDS             complement(2614..3375)
                     /locus_tag="VU534_001758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="HEU1514304.1"
                     /translation="MAKNVVITGATSGIGEAIARAYLEQGEDVVLTGRRIDRLEALKA
                     EFAETFPNQTVWTFLLDVTDMTMVKTVCSDILETIGQIDILVNNAGLALGLAPYQDYE
                     ELDMLTMLDTNVKGLMAVTRCFLPAMVKANQGHIINMGSTAGIYAYAGAAVYSATKAA
                     VKTFSDGLRIDTIATDIKVTTIQPGIVETDFSTVRFHGDKERAASVYQGIEALQAQDI
                     ADTVVYVTSQPRRVQITDMTIMANQQATGFMVHKK"
     gene            complement(3417..4043)
                     /locus_tag="VU534_001759"
     CDS             complement(3417..4043)
                     /locus_tag="VU534_001759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4479 and tRNA-binding domain-containing
                     protein"
                     /protein_id="HEU1514305.1"
                     /translation="MIFTYNKEHVGDVLMVIVKNSGDAKLDVERKGKVARVFLKDNGE
                     TVAWNIFEVSSLFEIAERGQVFLTDEQVARLNQELQAEGFTEEIVNDKEPKFVVGEIV
                     EMVAHPDSDHLNICQVAVASDKTVQIVAGAPNARVGLKTIVALPGAMMPKGNLIFPGE
                     LRGEKSFGMMCSPRELHLPNAPQKRGVLELSEDQVVGTPFDPAKHWTA"
     gene            complement(4059..4376)
                     /locus_tag="VU534_001760"
     CDS             complement(4059..4376)
                     /locus_tag="VU534_001760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000615765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HEU1514306.1"
                     /translation="MIQPASLEELASLVEKAGKKVFIFVADWCSDCRYIYPALPEIEE
                     TNPEFTFIRMDRDQYMDLAKLWDVYGIPSLVVLEKDKEIGRFVNRDRKSKQQINDFLA
                     GLK"
     gene            complement(4373..4672)
                     /locus_tag="VU534_001761"
     CDS             complement(4373..4672)
                     /locus_tag="VU534_001761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001013971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4651 domain-containing protein"
                     /protein_id="HEU1514307.1"
                     /translation="MNGMKAKKMWMAGLALLGIGSLALATKKVADDRKLMKTQEELTE
                     IVRDHFSDMGEIATLYVQVYESSLESLVGGVIFEDGRHYTFVYENEDLVYEEEVL"
     gene            complement(5009..5200)
                     /locus_tag="VU534_001762"
     CDS             complement(5009..5200)
                     /locus_tag="VU534_001762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000291825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein"
                     /protein_id="HEU1514308.1"
                     /translation="MYYSVDDVVSNAFKKRMILDSFFAFNCSGTMKVSTWVYDKGEWY
                     YVSSSGSMIANDWVKDNGK"
     gene            complement(5361..6035)
                     /locus_tag="VU534_001763"
     CDS             complement(5361..6035)
                     /locus_tag="VU534_001763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1514309.1"
                     /translation="MKKKAFGIVLLVLAAWILLQGNFGIPSLDGKIWPLLGIVFFAYK
                     SIESILRRHLTSAVFTGLLALIIANYAYDLLPVTNHSLIWASILVVLGVGYLTHSSKF
                     WNEKKWWYNGKKTVVTDKEVAFGSGTFYKQDQDLVDDQVEVAFGDAKIYYDNAEMLGD
                     FATLNIEVAFGNATVYVPQHWRVDLKVETSFGAAKADAPVAPTSKTLIIRGDVAFGKL
                     EIVYVK"
     gene            complement(6041..6487)
                     /locus_tag="VU534_001764"
     CDS             complement(6041..6487)
                     /locus_tag="VU534_001764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000776610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU1514310.1"
                     /translation="MKLRIEIDGNLEETEIVIKTPTLTDEIADLQRLLQESKAPRLTF
                     YKGTGEYYLDLSEILFFETEGSKIYAHNQKEAYEVRLKLYELESILPRYFNRVSKSTI
                     ANIRQIYSVDKSFSGTGTISFYQTHKEVHVSRHYQSLLKENLRNMR"
     gene            complement(6601..7104)
                     /locus_tag="VU534_001765"
     CDS             complement(6601..7104)
                     /locus_tag="VU534_001765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HEU1514311.1"
                     /translation="MKNYQEWYRNISSRLTSCPILLFLLRSFNRLMTVAMPLVYLILL
                     VTTYLQLGLGQQVGVYVLIPASGFVALSLFRKKINHPRPYETWDICPLLDKDSSGRSM
                     PSRHVFSATIISMACLHASLPIGLVCLIFSALLGLVRVLGGVHYPKDVLVGYACGLVW
                     GFLFFLF"
     gene            complement(7101..7463)
                     /locus_tag="VU534_001766"
     CDS             complement(7101..7463)
                     /locus_tag="VU534_001766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2200 domain-containing protein"
                     /protein_id="HEU1514312.1"
                     /translation="MSQKLYNMKFAAVYLALIAKVERKGGKAESVHQVTSWLTGYEVS
                     DVLACLDRDVTYGDFFRQAPYYVPERIAITGKICGVRIEEIDDPLMQEIRRLDKLVDW
                     LAKGKTSQQVLEKYEKHK"
     gene            complement(7529..9388)
                     /locus_tag="VU534_001767"
                     /pseudo
     CDS             complement(7529..9388)
                     /locus_tag="VU534_001767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001850459.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
     gene            complement(9427..9876)
                     /locus_tag="VU534_001768"
     CDS             complement(9427..9876)
                     /locus_tag="VU534_001768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HEU1514313.1"
                     /translation="MDKPMLVFKRFGHQIHLMVQKEAKRCGIEFMGGPQGQVVRFLDN
                     REKNQDLVLIKDIEQELNITKPVASNLVKRIVQNGLVELEASPVDKRAKFVRLTDKAR
                     SQMQQVKAFFERIDKQLMEDIDEDELLIFEKVLGQLQAKYQGNRRRE"
     gene            complement(10000..10716)
                     /locus_tag="VU534_001769"
     CDS             complement(10000..10716)
                     /locus_tag="VU534_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015604432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEU1514314.1"
                     /translation="MGRKWANIVAKKTAKDGANSKVYAKFGVEIYVAAKKGDPDPESN
                     SALKFVIDRAKQAQVPKHIIDKAIDKAKGNTDETFTEGRYEGFGPNGSMLIVDTLTSN
                     VNRTAANVRAAFGKNGGNMGASGSVSYLFDNKGVIVFGGEDADAVFEQLLEADVDVDD
                     VEAQEGTITVYTAPTDLHKAIVALRESGIEEFQVTELEMIPQSEVELSGEDLETFEKL
                     YSVLEDDEDVQKIYTNVDGF"
     gene            complement(11597..13012)
                     /gene="ply"
                     /locus_tag="VU534_001770"
     CDS             complement(11597..13012)
                     /gene="ply"
                     /locus_tag="VU534_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cholesterol-dependent cytolysin pneumolysin"
                     /protein_id="HEU1514315.1"
                     /translation="MANKAVNDFILAMNYDKKKLLTHQGESIENRFIKEGNQLPDEFV
                     VIERKKRSLSTNTSDISVTATNDSRLYPGALLVVDETLLENNPTLLAVDRAPMTYSID
                     LPGLASSDSFLQVEDPSNSSVRGAVNDLLAKWHQDYGQVNNVPARMQYEKITAHSMEQ
                     LKVKFGSDFEKTGNSLDIDFNSVHSGEKQIQIVNFKQIYYTVSVDAVKNPGDVFQDTV
                     TVEDLKQRGISAERPLVYISSVAYGRQVYLKLETTSKSDEVEAAFEALIKGVKVAPQT
                     EWKQILDNTEVKAVILGGDPSSGARVVTGKVDMVEDLIQEGSRFTADHPGLPISYTTS
                     FLRDNVVATFQNSTDYVETKVTAYRNGDLLLDHSGAYVAQYYITWNELSYDHQGKEVL
                     TPKAWDRNGQDLTAHFTTSIPLKGNVRNLSVKIRECTGLAWEWWRTVYEKTDLPLVRK
                     RTISIWGTTLYPQVEDKVEND"
     gene            complement(13023..13355)
                     /locus_tag="VU534_001771"
     CDS             complement(13023..13355)
                     /locus_tag="VU534_001771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1514316.1"
                     /translation="MYICIDNSMTKNKELVKNQTFKPALLTRRLVKNFMIEEPDLARN
                     PFTRPTLIDLDKVFMLDNTVIPTSYLARRRRNVSEELYEEILDYLVQPRLISLNKSEF
                     MQLNPGTY"
     gene            complement(13426..14034)
                     /locus_tag="VU534_001772"
     CDS             complement(13426..14034)
                     /locus_tag="VU534_001772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000083609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1514317.1"
                     /translation="MSQSSYLSPLLWLKKEADKEKMSATQCQIFFFYYQMFELLFARE
                     SDMKDLCLGTKGFYFSQLEKNLLSGVSRFLKNLEGKVTLKANQEVSARKALFLALTTS
                     QSDWQELAPVFDFYQTIGRLENPSLLSSQDRQHLMWIYQSALEKDYIVKVIGDKHFVL
                     KRQDATKLTARQTQTLEILSQSEDLVNPVYVTLGEKGVLLLD"
     gene            complement(14047..14505)
                     /locus_tag="VU534_001773"
     CDS             complement(14047..14505)
                     /locus_tag="VU534_001773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000186958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4231 domain-containing protein"
                     /protein_id="HEU1514318.1"
                     /translation="MTPEEMYLTERLDVQIAHFLKKSVQHRRRYKVLKITEIVAGFLI
                     AVFCAIPMPGDRYRLISVALSSLGLLCEGIINLYNAKENWISYQKTAQLLEKEKFLYQ
                     CQTEKYAGKTKAFALFVKTCEGLISEEINQWESIQSKEVAASADAPVKKE"
     gene            14630..>14816
                     /locus_tag="VU534_001774"
     CDS             14630..>14816
                     /locus_tag="VU534_001774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
                     /protein_id="HEU1514319.1"
                     /translation="MNYEASKQLTDARFKRLVGVQRTTFEEILAVLKTAYQLKHAKGG
                     RKPKLNLEDLLMATLQYV"
BASE COUNT         4296 a         3425 c         2694 g         4401 t
ORIGIN      
        1 aaaaagaagg gttagtcatt ccctcctttt gtgtttttta taagttgttt tctatagaaa
       61 gcttacatca tcccgcccat catgcttgga tccattgctg gagctggggc tactggttct
      121 ggtttattgg ctacgactgc ttctgttgtc aaaatcaagc tggctacaga tgctgcattt
      181 tgtagggctg aacgactcac tttaactgga tcaatgatac cttgatcaat catgttaacc
      241 cactcgccag ttgctgcgtt aaatcctata ccaagctcag catttttcaa acgatcgata
      301 acgatagatc cttcaaatcc tgcattgtga gcaatttgac gaacgggttc ttccaaagca
      361 cggagaacaa tattacgtcc tgttgcttca tctcctgtca attccaaggt agcaacagct
      421 ggaatcacat tggcaagagc tgttccacca cctgcaacaa taccttcttc aacagctgca
      481 cgagtagcgt tgagggcatc ttcaatgcgg agtttcattt ctttcaactc agtttcagtt
      541 gcggctccaa ccttaataac cgctacacca cctgacaatt tggccaagcg ttcttgcaat
      601 ttttcacggt caaattcaga agttgtagtt tcgatttgag acttgataac cgcaacacgg
      661 tgagaaatcg cttcaggatt tcctgcacct tctacaataa ccgtgctatc tttgtccacg
      721 gtcactctcg ctgcttgacc aagagcttca attgtcgcat ctttcaactc aagaccaagg
      781 tcttctgtga taactgttcc gcctgttaag atggcgatat cttcaagcat ggctttgcga
      841 cggtcaccaa aaccaggtgc cttgactgct actacgttga aggttccacg aatcttgttc
      901 aaaacaagag ttggaagagc ctcgccatcc acatcatccg caataatcaa gagtggacga
      961 ttgctttgga gaatgctttc caaaagtggc aagatttctt ggatattgga aattttcttg
     1021 tctgtaatca aaatgtacgg attttcaagg tcagccacca ttttttcgct atctgtcacc
     1081 atgtactgtg aaaggtaacc acggtcaaac tgcattcctt ctacgacttc aagctctgtt
     1141 tccataccac gtgactcttc gatggtgatg acaccgtctt tgccaacttt ttccattgct
     1201 tcagagatgt actcaccaac tttttcagaa cgagaagata cggctgcaac ttgagcgata
     1261 gcttctttat tggcaacagg gatggcgttg tttttcaaag cttcaactgc tgcggcaact
     1321 gctgtttcaa tcccacgacg aataccgatt ggatttgcac ctgctgtgac gtttttgatt
     1381 ccttcacgga cgatagcttg ggtcaagact gttgcagtcg tagttccgtc acctgcgata
     1441 tcattggttt tagaagctac ttctgatact aacttagcac ccatattttc aaaatggtct
     1501 tccaattcga tttctttggc aatggtcaca ccgtcattgg taatcaaggg tgaaccgaat
     1561 gacttttcaa gaacgacatt gcgacctttt ggtcccaagg ttactttaac agtgtctgca
     1621 aggatatcga caccacgaac catggctgaa cgggcatctg atgaaaattt aatttctttt
     1681 gacatactta ctttctcctt ctattcctca atgattgcca aaatgttagc ttcgcctacg
     1741 atgatgtact tttcatcgcc atctttgaca tcaagacctg cgtgggcttc aactaagaca
     1801 cgatctccag ttttaacact tggagcaacc aagtcaccgt tcaaggtacg aacaccttgt
     1861 ccagtagcca caacttgagc tgttttggtt ttttcttggg ctgagcctgc aaggacaaag
     1921 cctccaacag tttgttcttt ttcttctatt tttaagacca cacggtcccc taatggtttc
     1981 aacatctgat ttcctccata atgagataga tattattagc actctttgaa cttgagtgct
     2041 aattcatagt tctattgtat cacttggtca gaaataatca agaaaaaagt ctgactttct
     2101 caagataaaa agcctgagac caactcagac tttttaattc ttaaaatggc aattcttcct
     2161 cttccaagac caaatctgcc aaatcttggc ctgcattatt ttcacgcata gcacgttggg
     2221 cacgactttc caagagttgg aatcctgtga caagtacttc ggtcacgtag ttcatttggc
     2281 catttttctc aaagcgacgg gtacgcaatt ctccatcaac ggaaatgaga ctacctttgg
     2341 ttgcgtagct tgccaaagtt tctgctagtc tgccccatag gaccatattg acaaaatcag
     2401 cttcacgttc accgttttgg tctttgtaac gacggttcac agcgatagtt gctcgcgcta
     2461 ccgacttgtc attgttggtt ttgtgcaatt ctggtgtaga cgttaaacgt ccaatcaaga
     2521 taactttatt atacatattt tcttcctcct acttatctat tcgtaggaaa tcaaaaaaag
     2581 ttacagaaat ttgtaacttt tcgagaaaat tttttatttt ttatgaacca tgaaacctgt
     2641 cgcctgttga ttggccataa tggtcatatc tgtaatctga acacgacgag gttgactagt
     2701 cacatagact actgtatctg caatatcctg agcttgcaaa gcttctattc cttggtaaac
     2761 ggacgcagct cgttctttat caccatgaaa acgcactgta gaaaaatctg tttcgacaat
     2821 tccaggctga atggtcgtca ccttgatatc cgttgcgatg gtatcaattc gcagtccatc
     2881 tgaaaaggtc ttaactgccg ccttggtggc tgagtaaaca gctgcaccag cataggcata
     2941 aattcctgcg gttgacccca tattgataat atgaccttga ttggctttta ccattgctgg
     3001 caagaaacag cgagtgactg ccatcaaacc tttgacattg gtatccaaca tggtcagcat
     3061 atccaactct tcatagtctt gatagggagc taagccaaga gccagtcctg cgttattgac
     3121 caggatgtca atctgaccta tcgtttctaa aatatcagag cagacagtct ttaccattgt
     3181 catatccgtg acatctagga gaaaagtcca aactgtttga tttggaaaag tttctgcaaa
     3241 ctccgcctta agagcttcta gtctgtctat ccgtcgtcct gttagaacga catcctcacc
     3301 ctgctccaga taagcacgcg caatcgcttc accgattcct gatgtcgctc ctgtaatcac
     3361 aacatttttt gccatcttat ttccttctag ctggtctatc agatattaac aacttcttag
     3421 gcagtccagt gtttcgctgg gtcgaacggt gttccgacaa cttggtcttc tgataattca
     3481 agcaccccac gtttttgtgg agcatttggc agatgcaatt cacgaggact gcacatcata
     3541 ccaaaactct tttcaccacg aagttcacct gggaaaatga gattcccttt tggcatcata
     3601 gctccaggaa gcgcgacaat ggttttcaac cccacacgcg cattgggagc tcctgcaacg
     3661 atttgtacag tcttatcact tgcgactgca acttggcaga tgttgaggtg gtcactatct
     3721 ggatgggcta ccatctcaac aatttcacct acaacaaact taggttcctt atcattaaca
     3781 atttcttctg taaaaccttc cgcctgcaac tcttggttca aacgagcgac ttgctcatct
     3841 gtcaaaaaga cttgaccgcg ctctgcaatt tcaaataaac ttgaaacttc gaaaatattc
     3901 caagccactg tttccccatt atctttgaga aaaacacggg ctaccttgcc tttgcgctcc
     3961 acatccagtt tggcatctcc gctatttttc acgatgacca taaggacatc accgacatgt
     4021 tctttattat atgtaaaaat cattgtttcc tttttctcct atttcagtcc tgctaaaaag
     4081 tcattgattt gttgcttgct tttacggtcg cgattgacaa aacgaccgat ttccttgtcc
     4141 ttttctagaa caacaaggct aggaattccg taaacatccc agagtttggc caaatccata
     4201 tactgatctc ggtccattcg aataaaggtg aactctggat tggtctcctc aatctctggt
     4261 aaggcaggat aaatataacg acaatcgcta caccagtctg ccacaaaaat gaagaccttc
     4321 ttgcccgctt tttccactaa agatgctaat tcttctaaac ttgctggctg tatcataaga
     4381 cttcctcctc atagactagg tcttcatttt catagacaaa ggtataatga cggccatcct
     4441 caaaaatgac gccaccaacc aagctctcca gactgctttc gtaaacttga acataaaggg
     4501 tcgcaatttc ccccatgtcg gaaaaatggt ctcgcacaat ctctgtcaac tcttcctgag
     4561 tcttcatgag cttacggtca tctgcaactt ttttcgtagc aagagcaagg cttccgatac
     4621 ctagcagagc caagcctgcc atccacattt ttttagcttt cataccattc attttaacac
     4681 aaaaaaggct tcaggacaaa tgaggaagca gcagaaaagc aagtaaaaag cctcttcctt
     4741 taaggaaaag gacttcttat actcaatgaa aatcaaagac caaactagga agctagccgc
     4801 aggctgctca aagcactgct ttgaggttgt agatagaact gacgaagtca gctcaaaaca
     4861 ctgttttgag gttgtggatg aagctgacgt ggtttgaaga gattttcgaa gagtattatt
     4921 cttattgcca ggcacctaag ttgccaacgt agtaactatc aggtgtgtag gtattgcgaa
     4981 gcatcttacc tgatgaagcc agataatact acttgccatt gtctttgacc caatcattcg
     5041 caatcatgga accagaagaa cttacataat accattctcc cttgtcataa acccaagtac
     5101 tgactttcat ggttcctgag caattaaagg caaaaaaact gtccaatatc attcgttttt
     5161 taaaagcatt tgacactaca tcatctacgc tgtagtacat agatacatca aacgtaaaag
     5221 ccaaaatatc gaaaaatata caacttttaa aggcagcatt tcatttttta aagtctaaca
     5281 accatagaac tgaaatcaga gcaaggcatc aatttcctac tcttagtacg tctattttga
     5341 tggttgaagt gaagattttt ttatttaacg tagacaattt ccaacttccc aaaagccaca
     5401 tctccacgga taatcaaggt tttgctggtt ggggctacag gagcgtcagc cttagctgca
     5461 ccaaaggagg tttctacttt caaatctaca cgccagtgtt gtggaacata gacggttgca
     5521 ttcccgaagg ccacttcaat atttaaagtt gcaaaatcac ctagcatctc tgcattatca
     5581 tagtagattt tagcatcccc aaaagcgact tccacttggt catctacgag atcttgatct
     5641 tgcttataga aggtcccgct accaaaagcg acttccttat ccgtgacgac tgtttttttc
     5701 ccattgtacc accatttttt ttcattccag aacttacttg aatgcgtcag ataaccaaca
     5761 ccaagtacca ccaagatgct agcccaaata agagaatgat tggtaactgg taacaagtca
     5821 taagcgtaat ttgcaatgat gagcgccagt aaacctgtaa aaactgccga agtgagatga
     5881 cgtctaagga tggactcaat ggacttataa gcaaaaaaaa caatacctag taaaggccat
     5941 attttaccat ccaaagaagg aattccaaaa ttcccttgca gcaagatcca agctgctaaa
     6001 accaataaaa caataccaaa tgctttcttt ttcatgtttt ttacctcatg tttcttagat
     6061 tttcttttag gagggattgg taatgccgtg agacatgaac ctccttgtgc gtctgataaa
     6121 aggaaatggt gcccgttcct gaaaaggact tgtccactga gtaaatctga cggatgtttg
     6181 cgatcgttga cttggaaact cgattaaaat agcgaggcaa gatagactcc aactcataga
     6241 gcttgaggcg aacctcataa gcttccttct ggttatgagc gtagatcttg ctcccttctg
     6301 tttcaaagaa gagaatttct gacaggtcta gataatattc acctgtcccc ttgtaaaaag
     6361 tcaacctcgg agcctttgac tcttgcaaga ggcgttgcaa gtctgcaatt tcatctgtca
     6421 aagtgggggt cttgatgaca atttcagtct cctctaaatt gccgtcaatc tcaattcgta
     6481 acttcatcac atctcctttc tgactctact atatcaaagc taagttagga atacaagggc
     6541 aaaaaagcaa gtggtcaatt tgaagcagta agtggttgta ggactagctt aacttacatg
     6601 tcagaatagg aagaaaagga atccccacac caaaccacaa gcatagccaa ccaagacatc
     6661 cttgggataa tgaacacccc ctaaaaccct caccaacccc agcaaagctg aaaagatcaa
     6721 gcatactaag ccaataggta gactagcatg cagacaggcc atggagatga tagttgccga
     6781 aaagacatgg cgactgggca tcgaccgtcc cgaactatcc ttatcaagaa ggggacagat
     6841 atcccaagtt tcataaggtc tcgggtgatt gattttctta cgaaacaggg acaaggccac
     6901 aaaacctgat gcaggaataa gcacataaac cccaacttgc tgaccaagtc ctagttgcag
     6961 gtaagtggtg actagcaaga tcagatagac caggggcatg gcgactgtca tcaaacgatt
     7021 gaaactgcgt aataggaata aaagaattgg acaactagtt agtctggagc tgatatttcg
     7081 ataccattct tgataatttt tcatttatgc ttctcatact tttctagaac ttgttgagat
     7141 gttttcccct tggcaagcca atccactagc ttgtccaagc gacgtatttc ctgcatcaga
     7201 ggatcatcaa tttcctcaat acggacaccg caaatcttcc ctgtaattgc aattcgttca
     7261 gggacataat atggtgcttg tctaaaaaaa tctccgtaag taacatccct atccagacaa
     7321 gcaagaacat cactcacttc ataccctgtc aaccaactgg tcacttggtg aactgactct
     7381 gcctttccac cctttcgctc aacttttgca atcaaggcta agtagacagc agcaaatttc
     7441 atattgtata atttctgact catacttctc tctttctatg tgtactagta taaataagaa
     7501 aaagaaggcc gtcaagcctt cttttgattt attcttctgc ttcatcttct gtaaattgac
     7561 tattgtacaa gtcagcgtag aagccacctt gcgccatcag ttcctcatag ttgccttgct
     7621 cgatgatatt tccatctttc atgaccaaga tcaagtctgc atttcggatg gttgacaagc
     7681 ggtgggcaat gacaaaggat gtgcgtcctt ccatcaaacg gtccatggct ttttggatca
     7741 attcctctgt ccgtgtgtca acagaagaag tcgcctcatc caaaatcaaa agcggtgcat
     7801 ccttaagaag ggcacgagca atagtcaata gttgtttttg tcttacagac aaggtcacgg
     7861 tgtcatccaa gatggtatca tagccatctg gcaaggtcat aataaagtgg tgaattccca
     7921 cagccttact agcttccatc attcgttcat cactaatccc tatttgatta tagatgagat
     7981 tgtctcgaat agttccttca aagagccagg tatcctgcaa gaccattgaa aaggcatcat
     8041 gcacttctga acgcgtcata gccttggtat ccacaccatc aatgcgaata cttcccttat
     8101 caatctcata gaatttcatc aaaagattga caatggttgt cttaccagcc ccagtcggcc
     8161 caacaatggc aaccttttga ccagcatgag ctgtcgcaga gaagtcatag tcttgaacat
     8221 tgacaccgtc caccagaatt tctcctgctg acacgtcgta gaaacgtgga atcagattga
     8281 ccagagttga tttaccagaa cctgttgacc caataaaggc cactgtttga ccagtttctg
     8341 ctttaaagct aacatgttca ataactgcct ccgaatttgc cgcatagcgg aaggtcacat
     8401 ccttaaactc gacctgacct ttgaagtttt catcagtcag ctgcacttga acagggtttt
     8461 ggatagaaga atgcaaatct aaaacttgat taatccgctt agcagagacc atagttcggg
     8521 gaagaacgat gaagagtgct cccatgagaa ggaagcccat gacaacctac atggcataag
     8581 acatgaaaac aatcatgtca ctaaagagag gcagacgcgc tatcggagca gcgtcgttaa
     8641 tcacataggc cccaatccag taaatcgcca cactcaaacc acttgaaatc cccatcatga
     8701 taggattcaa aatagccata agacggttga caaacaaatt caaacgggtc aattcatcat
     8761 ttactgctgc aaatttttca ttttgataat cctctgcatt gtaggcacga acgacacgaa
     8821 tacctgttaa actctcacga gtgatactgt tcagtttatc tgtcagcccc tgaatcaagg
     8881 actgttttgg aaaggctagc gtcatcaaaa cggtcgtcat caggacgttg ataatcactg
     8941 ccacaagtac ggcccagagc cagtattctg aatgacctaa aatcttccca atagcccaga
     9001 tagccataat tgaaccacgc gttaccactt gcaagcccat agtaatcaac atttgaactt
     9061 gagtaatgtc attggtagta cgcgtcaaga ggctaggaat tgaaaatttc ttaatctctg
     9121 tctgcgagta atccaaaact cggttaaaaa tatcacttct cagcctacta gtataagaag
     9181 ccgccactcg ggatgcaaaa aatccaactg caactacgga caagaaggca agaaaggaca
     9241 ttcccatcat catgcttgcc gactgccaca actcatctaa attagtttct tgactaccta
     9301 gcaaatccgt aattttcgag atataggtcg gcacttccaa ctctagatag accgaaaagc
     9361 aagtaaagag aatggctagt aaaatcatcc cccattcttt tctactaatt cttttggcta
     9421 atttctttat tctctcctcc tattcccttg atattttgcc tgtagttgac cgagaacctt
     9481 ctcaaaaatc agtaattcat cttcatcaat gtcttccatc aactgcttgt ctatgcgttc
     9541 aaaaaaagcc ttaacctgtt gcatctgaga acgtgctttg tccgtcagac gaacaaactt
     9601 agcccgctta tcaacaggac tcgcctccaa ttccaccaaa ccattttgca ctatacgctt
     9661 aaccagatta ctagcaacag gcttggtaat attgagttcc tgctcgatat ctttaatcaa
     9721 gaccaagtct tggtttttct cgcgattatc caaaaaacgc acaacctgac cttgcggccc
     9781 acccataaat tcaatgccgc aacgtttggc ttccttttgc accatcaggt gaatttgatg
     9841 accaaaacgc ttaaagacta acatcggttt atccataatc tcccccttct aaataaaaat
     9901 agttctctgg agaataatta aatttctatg agaactattt tcttgattaa aaaaatccca
     9961 agtgattttc tcacttagga tcatgttcta taggttaaat taaaacccat ctacgttcgt
    10021 ataaatcttt tggacgtctt cgtcgtcttc aagaacgctg taaagttttt caaaggtttc
    10081 aaggtcttcg cctgacaatt ccacttctga ctgaggaatc atttccaatt cagtcacttg
    10141 gaattcttca ataccagact cacggagggc aacgatagcc ttgtgaaggt cagttggcgc
    10201 tgtgtaaact gtgattgtac cttcttgtgc ttctacgtca tccacatcca catccgcttc
    10261 gagcaattgc tcaaagactg cgtccgcatc ttcacctcca aatacaataa cacctttgtt
    10321 gtcaaagagg taagaaacag aacctgaagc gcccatgttt ccgccgtttt taccaaaggc
    10381 tgcacggaca ttggctgctg tacggttgac gttagaagtc aaagtatcca caattagcat
    10441 agagccattt ggcccaaaac cttcgtaacg tccttctgta aaggtttcgt ctgtgtttcc
    10501 tttggcttta tcaatcgctt tatcgataat gtgttttggc acttgggctt gtttagcacg
    10561 gtcgataacg aatttcaaag ctgagtttga ttctggatct ggatcacctt ttttagctgc
    10621 tacatagatt tctacaccaa attttgcata tactttagag ttagctccat ctttagccgt
    10681 tttcttggct acgatattgg cccatttacg tcccattagg aatctccttt tttcacattt
    10741 taatctttct tattataaca caagtttttt tgattttcac tagaggaaat ggattttatt
    10801 agcaaatcaa gctaggatag cactttacct gctaagatgg tcttgccttt ctatctttat
    10861 caacaggcac tcatccacat tcaaaaaaca aactagacca ttatctgcaa atagaaagtt
    10921 tcagccaagt ttgacaaagt cagctcaaat tactgtttga agtttgtaga tataagcgac
    10981 aaaaacaatc atactgcacc ttttgttgac agtctactcc agacatatca tagttcaagt
    11041 aaatactttg aaattcaaca gttcttatag gcgctattgt attctaagaa atcaatagaa
    11101 gagtttctaa gcaaacctct aatactcaat aaaaatcaaa gagcaaacta gaaagctagc
    11161 ctcaggttgc tcaaaacact gttttgaggt tgcggatggg gctgacatgg tttgaagaga
    11221 ttttcgaaga gtataattta cgtgttccca agatggagaa gttagactag tacactggca
    11281 cttctaaaac attgctagca attgatttgt tcatatttaa tttcattttt tccataaatg
    11341 ggtattagat ataaacagca aaatatttcc gatacgtgtc gttcttgaat ttccaatcat
    11401 ctaaaacaag taaaggataa tcaatcccct gtatatcaag gaattggcta ccctttttac
    11461 ttttttacac attctgtttg atagattcat tttaacatca cgagcatact ccaatggaaa
    11521 tcgctaggca agagataaac tttcagatat ccgcagagag atcatcgcct ctttttgtcg
    11581 caagcattct cctctcctag tcattttcta ccttatcttc tacctgagga tagagagttg
    11641 ttccccaaat agaaatcgtc cgcttacgca ctagtggcaa atcggttttt tcataaaccg
    11701 tacgccacca ttcccaggca agcccggtac actctctaat tttgacagag agattacgaa
    11761 cattcccttt taaaggaata ctagtggtaa agtgagccgt taaatcctgc ccatttctgt
    11821 cccaagcctt aggagtcaag acttccttac cttgatgatc ataggataat tcattccaag
    11881 taatataata ttgggcaaca taggcaccac tatgatccag cagtaaatct ccgtttctgt
    11941 aagctgtaac cttagtctca acatagtctg tactattttg aaaggtcgca actacattgt
    12001 cacgtaaaaa agaagttgta taggaaatcg gcaagcctgg atgatctgct gtaaagcgac
    12061 tgccttcttg aatcaagtcc tctaccatat ccaccttgcc tgttacaact cgggcacccg
    12121 aacttgggtc gccccctaaa ataaccgcct tcacttctgt attgtccaaa atctgtttcc
    12181 actctgtctg aggagctacc ttgactcctt ttatcaaagc ttcaaaagca gcctctactt
    12241 catcactctt actcgtggtt tccaacttga gatagacttg gcgcccataa gcaacactcg
    12301 aaatatagac caaaggacgc tctgcagaaa ttcctctctg ttttaaatcc tctaccgtta
    12361 cagtatcttg aaacacatct cctggatttt taacagcatc tacgctgact gtataataaa
    12421 tctgcttaaa attaacaatc tgaatctgct tttcgcctga atggacagag ttaaaatcaa
    12481 tatcaagaga attccctgtc ttttcaaagt cagaaccaaa cttgaccttg agttgttcca
    12541 tgctgtgagc cgtgattttt tcatactgca ttctagctgg gacattattg acctgaccat
    12601 aatcttgatg ccacttagcc aacaaatcgt ttaccgctcc gcgaacactt gaattgctgg
    12661 ggtcttccac ttggagaaag ctatcgctac ttgccaaacc aggcaaatca atactataag
    12721 tcatcggagc acgatcgacc gcaagaagag tgggattatt ctctaacaag gtctcatcca
    12781 ctacgagaag tgctccagga tagaggcgac tgtcgttggt agctgttaca gaaatatcac
    12841 ttgtatttgt cgacaagctc cgcttctttc tttcgataac aacaaactca tcgggtagct
    12901 gattaccctc tttgatgaaa cgattttcaa tactttctcc ctgatgggtc aagagtttct
    12961 ttttatcgta attcatagct agtataaagt catttactgc tttatttgcc atcttctacc
    13021 tcctaataag ttcctggatt gagttgcata aactcagact tgttcagcga aatcagccgt
    13081 ggttggacta agtaatccaa aatttcctcg tacaattctt ctgagacatt gcgtcgccgt
    13141 ctggctaaat aagaagtcgg aatgaccgta ttatccaaca taaatacctt atctaagtca
    13201 atcaaggttg gtcttgtaaa aggattacga gctagatccg gctcttctat cataaagttc
    13261 ttgaccaaac gtctggtcaa gagagctggt ttgaaggtct gatttttaac caactctttg
    13321 tttttagtca tgctgttgtc aatacagata tacatatgat tcttcacagc caaatcgcta
    13381 ctaatagtcg gaaaaggcaa ataaagagct acaacatctc ctctcttaat caagcaagag
    13441 cacccccttt tctcctaatg taacatagac aggattgacc aagtcttctg attgactcag
    13501 aatttccaaa gtttgagttt ggcgcgctgt caatttagta gcatcttgtc tcttcaatac
    13561 aaaatgcttg tcgccaataa ccttgacaat ataatccttc tccaaagctg actggtaaat
    13621 ccacatcaga tgttgtctgt cctgagaact caagagagaa ggattttcaa gcctcccgat
    13681 agtctgataa aaatcaaaaa caggagctaa ctcctgccaa tctgattggc tagttgtcaa
    13741 ggctagaaaa agggctttgc gagctgatac ttcttggtta gccttgagag ttactttccc
    13801 ctccaagttt tttagaaatc gggaaactcc agaaagcaaa tttttctcta actgcgagaa
    13861 ataaaaacct ttcgttccca gacataagtc tttcatgtcg ctttctctag caaataagag
    13921 ctcaaacatt tgatagtaaa agaaaaatat ctggcactgg gtcgcgctca tcttttcctt
    13981 atcggcttct ttttttaacc agagcaaggg cgacaggtag ctggattgag acatttcctc
    14041 tacctcctac tcttttttaa ctggagcatc tgcactagct gccacttctt ttgactggat
    14101 actttcccac tggttaatct cctctgagat aagaccttcg catgtcttga caaatagggc
    14161 aaaagccttg gtctttcctg catatttctc cgtttggcat tgatagagga atttttcttt
    14221 ctccaggagt tgcgcagttt tttggtaaga aatccaattt tcctttgcat tatacaaatt
    14281 gataatcccc tcacacagca agccgagact ggataaggca accgaaatca aacggtagcg
    14341 atcacctggc ataggaatag cacaaaagac agctatgagg aaacctgcca cgatttctgt
    14401 tatttttaat accttatagc gcctacgatg ttgaacgctt ttctttaaaa aatgagctat
    14461 ctgtacgtct aatcgctctg tcaggtacat ttcttctggc gtcatattcg taactccttt
    14521 catttacttt gataatcata gtataacata tttgaatatc aaagtatagt aaaaactgga
    14581 ctataactta ttagacttcc tgcgaaacaa aatatggtat agtagttcta tgaattatga
    14641 agcaagtaaa caactaactg atgcacgatt taagcgtctt gttggtgttc agcgcacgac
    14701 ttttgaagag atattagctg tattaaaaac agcttatcaa cttaaacacg caaaaggtgg
    14761 acgaaaacct aaattaaacc tagaagacct tcttatggcc actcttcaat atgtgc
//
LOCUS       DAVFER010000051        14702 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1105170250
            SAMEA2167659-rid19724873.denovo.051, whole genome shotgun sequence.
ACCESSION   DAVFER010000051 DAVFER010000000
VERSION     DAVFER010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2167659
            Sequence Read Archive: ERR388902
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14702)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14702)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928716.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928716.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 04:07:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,118
            CDSs (total)                      :: 2,073
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 120
            CDSs (without protein)            :: 120
            Pseudo Genes (ambiguous residues) :: 0 of 120
            Pseudo Genes (frameshifted)       :: 67 of 120
            Pseudo Genes (incomplete)         :: 47 of 120
            Pseudo Genes (internal stop)      :: 34 of 120
            Pseudo Genes (multiple problems)  :: 23 of 120
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14702
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2167659-rid19724873.denovo.051"
                     /strain="1105170250"
                     /db_xref="taxon:1313"
     gene            complement(<1..2333)
                     /locus_tag="VU534_001775"
     CDS             complement(<1..2333)
                     /locus_tag="VU534_001775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HEU1514320.1"
                     /translation="MDKNKIMGLTQREVKERQAEGLVNDFTASASTSTWQIVKRNVFT
                     LFNALNFAIALALAFVQAWSNLVFFAVICFNAFSGIVTELRAKHMVDKLNLMTKEKVK
                     TIRDGQEVALNPEELVLGDVIRLSAGEQIPSDALVLEGFAEVNEAMLTGESDLVQKEV
                     DGLLLSGSFLASGSVLSQVHHVGADNYAAKLMLEAKTVKPINSRIMKSLDKLAGFTGK
                     IIIPFGLALLLEALLLKGLPLKSSVVNSSTALLGMLPKGIALLTITSLLTAVIKLGLK
                     KVLVQEMYSVETLARVDMLCLDKTGTITQGKMQVEAVLPLTETYGEEAIASILTSYMA
                     HSEDKNPTAQAIRQRFVGDVAYPMISNLPFSSDRKWGAMELEGLGTVFLGAPEMLLDS
                     EVPEAREALERGSRVLVLALSQEKLDHHKPQKPSDIQALALLEILDPIREGAAETLDY
                     LRSQEVGLKIISGDNPVTVSSIAQKAGFADYHSYVDCSKITDEELMAMAEETAIFGRV
                     SPHQKKLIIQTLKKAGHTTAMTGDGVNDILALREADCSIVMAEGDPATRQIANLVLLN
                     SDFNDVPEILFEGRRVVNNIAHIAPIFLIKTIYSFLLAVICIASALLGRSEWILIFPF
                     IPIQITMIDQFVEGFPPFVLTFERNIKPVEQNFLRKSMLRALPSALMVVFSVLFVKMF
                     GASQGWSELEISTLLYYLLGSIGFLSVFRACMPFTLWRVLLIVWSVGGFLATALFPRI
                     QKLLEISTLTEQTLPVYGVMMLVFTVIFILTSRYQAK"
     gene            2466..3215
                     /locus_tag="VU534_001776"
     CDS             2466..3215
                     /locus_tag="VU534_001776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HEU1514321.1"
                     /translation="MFYTYLRGLVVLLLWSINGNAHYHNTDKIPNQDENYILVAPHRT
                     WWDPVYMAFATKPKQFIFMAKKELFTNRIFGWWIRMCGAFPIDRENPSASAIKYPINV
                     LKKSDRSLIMFPSGSRHSNDVKGGAALIAKMAKVRIMPVTYTGPMTLKGLISRERVDM
                     NFGNPIDISDIKKMNDEGIETVANRIQTEFQRLDEETKQWHNDKKPNPLWWFIRIPAL
                     ILAIILAILTIIFSFIASFIWNPDKKREELA"
     gene            complement(3507..4121)
                     /locus_tag="VU534_001777"
     CDS             complement(3507..4121)
                     /locus_tag="VU534_001777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000531723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CadD family cadmium resistance transporter"
                     /protein_id="HEU1514322.1"
                     /translation="MGQTIISAIGVYISTSIDYLIILIILFAQLSQNKQKWHIYAGQY
                     LGTGLLVGASLVAAYVVNFVPEEWMVGLLGLIPIYLGIRFAIVGEDAEEEEEEIIERL
                     EQSKANQLFWTVTLLTIASGGDNLGIYIPYFASLDWSQTLVALLVFVIGIIIFCEISR
                     VLSSIPLIFETIEKYERIIVPLVFILLGLYIMYENGTIETFLIV"
     gene            complement(4937..5206)
                     /gene="rpsO"
                     /locus_tag="VU534_001778"
     CDS             complement(4937..5206)
                     /gene="rpsO"
                     /locus_tag="VU534_001778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HEU1514323.1"
                     /translation="MAISKEKKNEIIAQYARHEGDTGSVEVQVAVLTWEINHLNEHIK
                     QHKKDHATYRGLMKKIGRRRNLLAYLRKNDVNRYRELINSLGLRR"
     gene            complement(5347..5976)
                     /locus_tag="VU534_001779"
     CDS             complement(5347..5976)
                     /locus_tag="VU534_001779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HEU1514324.1"
                     /translation="MKLAVIAANGQAGKAIVEEAVKRGHEVTAIVRSENKSQAESIIK
                     KDLFELTKDDLTGFDAVISAFGAYTPDTLPLHSKSIELFNQLLAGTQTRFLVVGGAGS
                     LYIDETKTTRLLDTPDFPEEFKPLAKAQADELDLLRTKNNLNWTFVSPAVDFIPDGEK
                     TGNYILAGEIFTTNEKGISQISYADYAIGLVDELEKGHHIKERISLLEK"
     gene            6213..6413
                     /locus_tag="VU534_001780"
     CDS             6213..6413
                     /locus_tag="VU534_001780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001826938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1514325.1"
                     /translation="MRRFYSHLPYYLVILFFYWPLYELFLLVVSDPLTLKGLYINNLL
                     FFTPLVILIVSLLYSYRFRFSL"
     gene            6844..7167
                     /locus_tag="VU534_001781"
     CDS             6844..7167
                     /locus_tag="VU534_001781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000422771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like protein"
                     /protein_id="HEU1514326.1"
                     /translation="MELQELVERSWAIRQAYHELEVKHHDSKWTVEEDLLALSNDIGN
                     FQRLVMTKQGRYYDETPYTLEQKLSENIWWLLELSQRLDIDILTEMENFLSDKEKQLN
                     VRTWK"
     gene            7225..9168
                     /gene="thrS"
                     /locus_tag="VU534_001782"
     CDS             7225..9168
                     /gene="thrS"
                     /locus_tag="VU534_001782"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000608363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HEU1514327.1"
                     /translation="MINITFPDGAVREFESGVTTFEIAQSISNSLAKKALAGKFNGKL
                     IDTTRAITEDGSIEIVTPDHEDALPILRHSAAHLFAQAARRLFPDIHLGVGPAIEDGF
                     YYDTDNTAGQISNEDLPRIEEEMQKIVKENFPSIREEVTKDEAREIFKNDPYKLELIE
                     EHSEDEGGLTIYRQGEYVDLCRGPHVPSTGRIQIFHLLHVAGAYWRGNSDNAMMQRIY
                     GTAWFDKKDLKNYLQMREEAKERDHRKLGKELDLFMISQEVGQGLPFWLPNGATIRRE
                     LERYIVNKELVSGYQHVYTPPLASVELYKTSGHWDHYQEDMFPTMDMGDGEEFVLRPM
                     NCPHHIQVFKHHVHSYRELPIRIAEIGMMHRYEKSGALTGLQRVREMSLNDGHLFVTP
                     EQIQEEFQRALQLIIDVYEDFNLTDYRFRLSLRDPQDTHKYFDNDEMWENAQTMLRAA
                     LDEMGVDYFEAEGEAAFYGPKLDIQIKTALGKEETLSTIQLDFLLPERFDLKYIGADG
                     EDHRPVMIHRGVISTMERFTAILIENYKGAFPTWLAPHQVTLIPVSNEKHVDYAWEVA
                     KKLRDRGVRADVDERNEKMQFKIRASQTSKIPYQLIVGDKEMEDETVNVRRYGQKETQ
                     TVSVDNFVQAILADIANKSRVEK"
     gene            complement(9217..10191)
                     /locus_tag="VU534_001783"
     CDS             complement(9217..10191)
                     /locus_tag="VU534_001783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HEU1514328.1"
                     /translation="MLDWKQFFLAYLRSRSRLFIYLLSLAFLVLLFQFLFASLGIYFL
                     YFFFLCCFVTILFFTWDILVETQVYRQELLYGEREAKSPLEIALAEKLEAREMELYQQ
                     RSKAERKLTDLLDYYTLWVHQIKTPIAASQLLVAEVVDRQLKQQLEQEIFKIDSYTNL
                     VLQYLRLESFHDDLVLKQVQIEDLVKEIIRKYALFFIQKGLNVNLHDLDKEIVTDKKW
                     LLVVIEQIISNSLKYTKEGGLEIYMDDQELCIKDTGIGIKNSDVLRVFERGFSGYNGR
                     LTQQSSGLGLYLSKKISEELGHQIRIESEVGKGTTVRIQFAQVNLVLE"
     gene            complement(10184..10861)
                     /locus_tag="VU534_001784"
     CDS             complement(10184..10861)
                     /locus_tag="VU534_001784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000548969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU1514329.1"
                     /translation="MHKILLIEDDQVIRQQIGKMLSEWGFEVVLVEDFMEVLSLFVQS
                     EPHLVLMDIGLPLFNGYHWCQEIRKISKVPIMFLSSRDQAMDIVMAINMGADDFVTKP
                     FDQQVLLAKVQGLLRRSYEFGRDESLLEYAGVILNTKSMDLHYQGQVLNLTKNEFQIL
                     RVLFEHAGNIVARDDLMRELWNSDFFIDDNTLSVNVARLRKKLEEQGLVGFIETKKGI
                     GYGLKHA"
     gene            11017..12090
                     /locus_tag="VU534_001785"
     CDS             11017..12090
                     /locus_tag="VU534_001785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2974 domain-containing protein"
                     /protein_id="HEU1514330.1"
                     /translation="MANIFDYLKDVAYDSYYDLPLNELDILTLIEITYLSFDNLVSTL
                     PQRLLDLAPQVPRDPTMLTSKNRLQLLDELAQHKRFKNCKLSHFINDIDPELQKQFAA
                     MTYRVSLDTYLIVFRGTDDSIIGWKEDFHLTYMKEIPAQKHALRYLKNFFAHHPKQKV
                     ILAGHSKGGNLAIYAASQIEQSLQNQITAVYTFDAPGLHQELTQTAGYQRIMDRSKIF
                     IPQGSIIGMMLEIPAHQIIVQSTALGGIAQHDTFSWQIEDKHFVQLDKTNSDSQQVDT
                     TFKEWVATVPDEELQLYFDLFFGTILDAGISSINDLASLKALEYIHHLFVQAQSLTPE
                     ERETLGRLTQLLIDTRYQAWKNR"
     gene            complement(12181..12483)
                     /locus_tag="VU534_001786"
     CDS             complement(12181..12483)
                     /locus_tag="VU534_001786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000281600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1514331.1"
                     /translation="MYLVIGIVLAFIVSFWKDNRSLWNPVLFLLSLISSYFYLSYLFY
                     KNGYENVQLAFYIFAFVLLPFLLFLSGIFLIYNGVILLKREGRSKPHYLSMLFDFY"
     gene            complement(12551..12988)
                     /locus_tag="VU534_001787"
     CDS             complement(12551..12988)
                     /locus_tag="VU534_001787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004263219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HEU1514332.1"
                     /translation="MQIPSRFTIATHMLIIIALEGKESKVTSDFLAASVGVNPVIIRK
                     ILSQLKKAELISVARGTGGTEIVKDLKDISLLDVYQAVECLGKTGQLFSFHDNPNPNC
                     PVGAHIHDVLDQKLERIQLTMEAELGQTSLEKVVADAESQMKD"
     gene            complement(13064..13906)
                     /locus_tag="VU534_001788"
     CDS             complement(13064..13906)
                     /locus_tag="VU534_001788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HEU1514333.1"
                     /translation="MTKIALLSDIHGNTTALEAVLADARQIGVDEYWLLGDILMPGTG
                     RRRILDLLDQLPITARVLGNWEDSLWHGVRKELDSTRPSQRYLLRQCQYVLEEISLEE
                     IEVLHNQPLQIHRQFGDLTVGISHHLPDKNWGRELIHTGKQEEFDRLVTHPPCDIAVY
                     GHIHQQLLRYGTGGQLIVNPGSIGQPFFLDAQLRKDLRAQYMILEFDDKGLVDMDFRR
                     VDYDVAAELQLAKDLRLPYFEVYYESLVNGIHHTHHQEFLRELAQKEGCDRELDDWLK
                     SGND"
     gene            14018..14668
                     /locus_tag="VU534_001789"
     CDS             14018..14668
                     /locus_tag="VU534_001789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000188500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HEU1514334.1"
                     /translation="MTPNKEDYLKCIYEIGIDLHKITNKEIAARMQVSPPAVTEMIKR
                     MKSENLILKDKECGYLLTDLGLKLVSELYRKHRLIEVFLVHHLDYTSDQIHEEAEVLE
                     HTVSDLFVERLDKLLGFPKTCPHGGTIPAKGELLVEINNLPLADIKEAGAYRLTRVHD
                     SFDILHYLDKHSLHIGDQLQVKQFDGFSNTFTILSNDEDLQVNMDIAKQLYVEKIN"
BASE COUNT         4480 a         3344 c         2756 g         4122 t
ORIGIN      
        1 tttttcgctt ggtaacgact ggtcaggatg aaaatcacgg taaagaccaa catcatgaca
       61 ccataaacag gcaacgtttg ttctgttaag gttgaaattt caagcagttt ttgaattctt
      121 gggaagagag ctgtggctag gaaacctcct actgaccaaa caatcaagag gacacgccat
      181 agggtaaatg gcatgcaggc tctaaatacg gataagaaac caattgaccc caagagataa
      241 tagagtagag ttgagatttc taactcagac caaccttgac tcgcgccaaa cattttcaca
      301 aacaggacgc tgaagacgac catgagagcg cttggtaggg cacgaagcat ggattttctg
      361 aggaaattct gctcaacagg tttgatattt cgctcaaaag tcagaacgaa tggtgggaaa
      421 ccttccacaa actggtcaat catggtaatc tggatcggaa tgaaggggaa aatcaaaatc
      481 cactctgacc gacctagtaa agcactggca atacagatga ctgctaacag gaaggaatag
      541 atggtcttta tcaagaaaat cggggcgatg tgggcaatgt tattgaccac gcgacgaccc
      601 tcgaagagaa tctcaggaac atcattaaag tctgagttca agagaaccag attggcaatc
      661 tgacgggttg ctggatcccc ctccgccatc acgatagaac aatccgcctc acgaagggcc
      721 aagatatcat taaccccgtc ccctgtcata gccgttgtat gtcccgcttt tttcaacgtt
      781 tggatgatga gtttcttttg atgaggggaa acacgtccga aaatagctgt ctcctccgcc
      841 atggccatca attcctcatc ggtgattttt gagcaatcta catagctgtg atagtccgca
      901 aaaccagcct tctgggcaat gctggacacc gtaactggat tgtcaccaga gataatcttg
      961 agtcccacct cctgagaacg gagatagtcc agcgtctctg ctgctccctc tcgaatgggg
     1021 tccaagattt ccagcaaggc tagagcctga atatcagatg gtttctgtgg tttgtgatgg
     1081 tctaatttct cctgactgag agctaagacc aagacacgtg atcctctctc caaggcctcc
     1141 ctagcttctg ggacttcaga atcaagcaac atctcaggtg cccctaagaa aactgtcccc
     1201 aagccttcta actccatagc cccccacttg cggtcgctcg agaagggaag attggaaatc
     1261 ataggataag caacatctcc cacaaaacgc tggcgaatgg cttgggcagt tggattctta
     1321 tcctcactat gggccatgta gctagtcaag atgctggcaa tagcctcttc accatacgtt
     1381 tccgtcaacg gaagaacagc ctccacctgc atctttcctt gggtgatggt acccgtcttg
     1441 tccagacaga gcatatccac gcgcgccaag gtctcaacag agtacatctc ctgcaccaag
     1501 acctttttca agcccaactt aatcactgca gtcaagagcg aagtaatggt caaaagggca
     1561 attcccttag gcaacattcc caaaagagct gtcgacgagt ttacaacgga tgacttgaga
     1621 ggcaggcctt ttaaaagcaa ggcttccagc aagagagcca gaccaaaggg aatgataatc
     1681 ttcccagtaa aaccagccaa cttgtccagc gatttcatga tacgggagtt gatgggttta
     1741 acggtcttag cctcaagcat gagtttggca gcatagttgt ctgcaccgac atggtgaact
     1801 tgagataaaa ctgacccact ggctaggaaa cttcctgaca aaagtaagcc gtcaacttcc
     1861 ttttgcacca aatcactttc tcccgttaac atggcttcat tgacttccgc aaagccttcc
     1921 aaaaccaagg catcactagg aatctgctct cctgcagaca aacgaatgac atctcctagc
     1981 actaattctt caggattaag agcaacttcc tgaccatcac ggatggtttt gaccttttcc
     2041 ttggtcatga gattgagctt gtccaccatg tgtttggctc gtagctcggt cacaatccca
     2101 gaaaaagcgt taaagcagat aacagcaaag aagaccagat tgctccaagc ctgcacaaag
     2161 gcaagagcca aagcaatggc aaagttcaaa gcgttaaaaa gggtaaagac atttcgttta
     2221 acgatttgcc aagtgctggt actggctgat gcggtaaagt cattgaccaa accctcagcc
     2281 tgtctttcct tgacttctct ttgggttaat cccataatct tatttttatc cataaattct
     2341 attatatcat tttttttaac agaattctaa tttcatccta aatatgtatc tagtcaaggg
     2401 aaaagtttgc cagccctcct ttgataaggt ataataataa caagaaaaca atcgaaggag
     2461 atcgcatgtt ttatacttat ttgcgtggat tagttgtatt gctcttatgg tccatcaatg
     2521 gcaatgctca ctatcataat actgataaaa ttcctaatca agatgaaaat tatattttag
     2581 ttgcgcctca ccgtacctgg tgggatcctg tttatatggc ctttgcgacc aagccaaaac
     2641 agttcatctt tatggcaaaa aaagaactct ttaccaaccg tatctttggt tggtggattc
     2701 gtatgtgtgg cgcctttccc atcgaccgtg aaaatcccag cgcctcagcc atcaaatatc
     2761 ctatcaacgt tctcaaaaaa agtgaccgct ctctcatcat gtttccaagt ggtagccgcc
     2821 actcaaacga tgtcaagggg ggcgcagcac tgattgccaa aatggccaag gtccgtatca
     2881 tgccggttac ctacaccggt cccatgactt tgaagggctt gattagccgt gaacgtgtcg
     2941 atatgaactt tggaaatcca atcgatatct cagatatcaa gaaaatgaat gatgaaggca
     3001 ttgaaacagt cgccaatcgt attcaaacag aattccaacg tctggacgaa gaaacgaaac
     3061 aatggcacaa tgataaaaaa ccaaatccac tctggtggtt tatccgcatc cctgccctca
     3121 tccttgctat tatcctcgct atcctaacca tcatctttag ctttatcgca agcttcatct
     3181 ggaacccaga taagaaaaga gaagaacttg catagaagaa atgaaccttg gccaaacagc
     3241 taaggttttc atttatatag tagattggaa ctagaatagt acacctctac ttctaaaaca
     3301 tttttagaaa tcgatttgac tgtcctgatc gatttgtcct attcttattt cattttacta
     3361 tatttataag aatctcctaa tcaaatcaaa agccactcta caatagagta actttaagat
     3421 tgtccattta tactcaatga aaaagccctc tgaaaatcag agagctgatt tgagctcggg
     3481 ctaaaatcct agtgaaacaa aaaaatctac acgatcagaa aagtctctat cgtgccattt
     3541 tcatacatga tgtatagtcc aagtagaatg aatactaagg gcacaatgat tcgctcgtat
     3601 ttttcaattg tctcgaatat taacggaata gaggataaca cccgactaat ctcgcaaaag
     3661 ataattatgc cgattacaaa cacaagcaag gccacgaggg tctgtgacca atctaacgaa
     3721 gcaaaataag gtatatagat acctaaatta tctccgccag acgcaattgt cagcaatgta
     3781 actgtccaaa acagttgatt tgccttgctt tgttctaatc tttcaataat ttcttcctct
     3841 tcttcttccg catcttctcc aacaattgca aagcgaatcc ctaaatagat agggattaaa
     3901 ccaagcaatc caaccatcca ttcttcaggc acgaaattaa cgacataagc agcaactaaa
     3961 ctcgccccta caagtaagcc tgtgcctaga tattgccccg cataaatatg ccatttctgt
     4021 ttattctgtg atagctgtgc aaataaaata attaaaataa ttaaataatc gatactggtg
     4081 gaaatataaa caccaatagc agatatgatt gtctgtccca taaaaaaaac ctcctgtatt
     4141 agtcagtaat aaatcagcag attttaggag agcacagaca cattaattta gctatcgcta
     4201 gtgggtaata tcgaacgtag gaaagcattt tactcctcct caaaacgtag ttacaaagta
     4261 atttctaact ggaattcagt gactacttcc atgtaaagta taacatacta tactttactt
     4321 tgtaaagagt gggctcttct agggggcttg catacagcta ctcggcttga aaagccgagt
     4381 aactgcgcac ctttatggtg taattagctg ataccgtttg aggtttttgt agtctccaaa
     4441 attgttaccg ataaaacctc aataaaaaag ccctctgaag tcagagagct gatttgagcc
     4501 cgggctaaaa tcctagtgaa aaagatgaaa ctccttgtgc tcatcgaaca ctgtgtcatt
     4561 tccctatttt catacggatt tttgacgccc ttagcatcat gattcttgct agataaatcg
     4621 tttatagact aggcgacgag gcgaagatcg tacgaaactt tcagtgaaac aaaaaaaatc
     4681 tccccgaagg gagaaaagct ggtttatttt accttacagt gctaggaacc gtaaccaaag
     4741 attatacttg agtatatcga ggtaaggtga caacgcaaaa aagctaccca atttagagta
     4801 gctttattat caagatatgc tcaattgaac acggcctaag cacttggcaa aaaagataaa
     4861 atctcctaga aactgaagtt tcttcgtcaa ttttcctatt tttgctttgt gcttttgacg
     4921 gcctttgtat cttgaattag cgacgaagtc ctagagagtt gatcaactca cggtaacggt
     4981 taacgtcgtt tttacgcaag tatgcaagca agttacgacg gcgaccgatt tttttcatca
     5041 atccacggta agtagcgtgg tcttttttgt gttgtttgat gtgttcgtta aggtggttga
     5101 tttcccaagt aaggacagca acttgaacct ctactgaacc tgtatcacct tcgtgacgtg
     5161 catattgtgc gatgatttca ttttttttct cttttgagat tgccatgatg tttctccttt
     5221 ttatttggct tcatccgagt gacaggttgg catgcctgta accaagaaga agttatttgt
     5281 ctttacgaca atccctattt taccaagatt taaattttct gtcaaacatt aatactctca
     5341 tagttattat ttttcaagta aagagatacg ttcttttata tgatgacctt tttcaagttc
     5401 atctaccaat ccaatagcat aatctgcata actaatctgg cttattcctt tttcattagt
     5461 agtaaaaatt tctcctgcta gaatgtagtt tcctgttttt tcaccatcgg gaataaaatc
     5521 tacagcagga ctgacaaaag tccagttgag attatttttt gtacgaagaa gatccaattc
     5581 atccgcttga gcttttgcta gtggcttaaa ttcttcagga aaatcaggcg tatctaaaag
     5641 tcgtgtcgtt tttgtttcat ctatataaag acttcctgct ccccctacaa ctagaaaacg
     5701 tgtctgtgtt ccagcaagaa gctgattaaa tagttcgatt gatttgctgt ggagcggtag
     5761 cgtatctggt gtataagcac caaacgctga aataacagca tcaaatccag taagatcatc
     5821 ttttgtcaac tcaaataaat cttttttaat aatagactca gcttgacttt tgttttcaga
     5881 acgaacaata gccgttactt catgtcctcg tttgactgct tcttcaacaa ttgctttccc
     5941 cgcttgtcca tttgctgcaa taactgctag tttcattttt tatacctctc ttgttgtaat
     6001 tattttagtt acagaaattg tgacactctt aataatcaat gtcaatagtc ttgcttaatt
     6061 attatcaaaa tatttctacc aagaaaacta accatgattc tagtgaaaaa aaatcttctt
     6121 tgtcaacaaa tttactttct tgttttaaac atgctataat aatcatagca agagatctaa
     6181 gttgtctgtt tttttaaaac gaggtgatta tcatgcgtag attctattcc catctcccct
     6241 actatctggt catattattc ttttattggc cactttatga gttgttctta ctagttgttt
     6301 ctgaccccct tacactcaag ggactctata taaacaatct tctcttcttt acacctctgg
     6361 taatcttgat tgtatcgtta ctctatagct accgtttccg tttctcactt tgatggttag
     6421 ttggtaacgg actgctcttt tactttacta tcataacctt tggtgagttt atactaattt
     6481 acttgctaat ctatgaaaca gttgctctgg tcggcatgga ttctggtatt agcatcaagc
     6541 atattctaca aaaaatgaaa aacaaaaaac tttcacaaaa tccttgaaaa atctcacaat
     6601 catgctataa taatccatag agacaagtca cttagtccct ttctactaga gagtgcgtgg
     6661 ttgctggaaa cgcataggaa gtctaaactg atactactct tgagtttttt atgaaaacat
     6721 aaaacggtgg ccacgttaga gccgatcaga ggtgtccctc tcttttgagg tacataaatg
     6781 aaggtggaac cacgttgcga cgtcctttcg aggatgtcgc atttttttat taggatacta
     6841 attatggagt tgcaagaatt agtggagcgc agttgggcaa tccgacaagc ttatcacgaa
     6901 ctggaagtta agcatcatga ttccaagtgg acggtagaag aagacctctt ggctttatct
     6961 aatgatattg gaaatttcca acgactggtg atgacaaagc aaggacgcta ctatgatgaa
     7021 acaccctaca cactggaaca aaaactttca gaaaatatct ggtggctatt agaactttct
     7081 caacgtttgg atatagacat tctgacggaa atggaaaact tcctctctga taaagaaaag
     7141 caattgaacg ttaggacttg gaagtagtct gctgataaaa aatcaatgct tagaaactat
     7201 gaaataataa aaaaggagaa catcatgatt aacattactt tcccagatgg cgctgttcgt
     7261 gaattcgaat ctggcgtaac aacttttgaa attgcccaat ctatcagcaa ttccctagct
     7321 aaaaaagcct tggctggtaa attcaacggc aaactcatcg acactactcg cgctatcact
     7381 gaagatggaa gcatcgaaat tgtgacacct gatcacgaag atgcccttcc aatcttgcgt
     7441 cactcagcag ctcacttgtt cgcccaagca gctcgtcgtc ttttcccaga cattcacttg
     7501 ggagttggtc cagccatcga agatggtttc tactacgata ctgacaacac agctggtcaa
     7561 atctctaacg aagaccttcc tcgtatcgaa gaagaaatgc aaaaaatcgt caaagaaaac
     7621 ttcccatcta ttcgtgaaga agtgactaaa gacgaggcac gtgaaatctt caaaaatgac
     7681 ccttacaagt tggaattgat tgaagaacac tcagaagacg aaggcggttt gactatctat
     7741 cgtcagggtg aatatgtaga cctctgccgt ggacctcacg ttccatcaac aggtcgtatc
     7801 caaatcttcc accttctcca tgtagctggt gcgtactggc gtggaaacag cgacaacgct
     7861 atgatgcaac gtatctacgg tacagcttgg tttgacaaga aagacttgaa aaactacctt
     7921 caaatgcgtg aagaagctaa ggaacgtgac caccgtaaac ttggtaaaga gcttgacctc
     7981 tttatgattt cacaagaagt gggacaaggt ttgccattct ggttgccaaa tggtgcgact
     8041 atccgtcgtg aattggaacg ctacatcgta aacaaagagt tggtttctgg ctaccaacac
     8101 gtctacactc caccacttgc ttctgttgag ctttacaaga cttctggtca ctgggatcat
     8161 taccaagaag acatgttccc aaccatggac atgggtgacg gggaagaatt tgtccttcgt
     8221 ccaatgaact gtccgcacca catccaagtt ttcaaacacc atgttcactc ttaccgtgaa
     8281 ttgccaatcc gtatcgctga aatcggtatg atgcaccgtt acgaaaaatc tggtgccctc
     8341 actggccttc aacgtgtacg tgaaatgtca ctcaacgacg gtcacctatt cgttactcca
     8401 gaacaaatcc aagaagaatt ccaacgtgcc cttcagttga ttatcgatgt ttatgaagac
     8461 ttcaacttga ctgactaccg cttccgcctc tctcttcgtg accctcaaga tactcataag
     8521 tactttgata acgatgagat gtgggaaaat gcccaaacca tgcttcgtgc agctcttgat
     8581 gaaatgggcg tggactactt tgaagccgaa ggtgaagcag ccttctacgg accaaaattg
     8641 gatatccaga ttaaaactgc ccttggaaaa gaagaaaccc tttctactat ccaacttgat
     8701 ttcttgttgc cagaacgctt cgacctcaaa tacatcggag ctgatggcga agatcaccgt
     8761 ccagtcatga tccaccgtgg ggttatctca actatggaac gcttcacagc tatcttgatt
     8821 gagaactaca agggggcctt cccaacatgg ctggcaccac accaagtaac cctcatccca
     8881 gtatctaacg aaaaacacgt ggactacgct tgggaagtgg ccaagaaact ccgtgaccgc
     8941 ggtgtccgtg cagacgtaga tgagcgcaat gaaaaaatgc agttcaagat ccgtgcttca
     9001 caaaccagca agattcctta ccaattaatt gttggagaca aagaaatgga agacgaaaca
     9061 gtcaacgttc gtcgctacgg ccaaaaagaa acacaaactg tctcagttga taattttgtt
     9121 caagctatcc tagctgatat cgccaacaaa tcacgcgttg agaaataaga gtctagcata
     9181 aaagcctcca atctggaggc tttttctcat ctatttttac tcaaggacta agttcacttg
     9241 agcaaactga atccgcactg tcgttccttt tccgacctca gactcgatac gaatctggtg
     9301 ccccagttct tcagaaattt tcttagatag ataaaggcca agtccagagg actgctgggt
     9361 caaacggcca ttgtatcctg aaaagccacg ttcaaatact cggaggacat cactgttttt
     9421 tatcccgatt cccgtatctt tgatacaaag ctcttggtca tccatataaa tctccagacc
     9481 accttccttg gtgtacttga gactgtttga gatgatttgc tcaataacca ctagcagcca
     9541 ctttttatcc gtcacgattt ctttatcaag gtcatgtaga ttgacattta agcctttttg
     9601 aataaagaaa agagcatatt tacgaattat ttccttgacc aagtcctcaa tttgaacctg
     9661 ctttaagacc aaatcatcat ggaaactttc taaacgcagg tactgtaaaa ctaggttggt
     9721 ataggagtcg attttgaaaa tttcctgttc tagctgctgc ttcagttggc ggtcgaccac
     9781 ttctgcaact aagagttgac tggctgcaat gggggtcttt atctgatgga cccacaaggt
     9841 atagtaatcc agcaaatccg tcagttttct ttctgctttt gacctctgct gatagagttc
     9901 catctcacgc gcttctaatt tttctgctaa agctatttcc aaaggagact tggcttccct
     9961 ctctccatag agaagttcct ggcgatagac ctgcgtttcc accaatatgt cccaagtgaa
    10021 aaataatatg gttacaaagc aacacaagaa gaaaaagtag aggaagtaaa ttcctagact
    10081 ggcaaataaa aactgaaaga gtaagacaag aaatgccaaa gaaagcagat agataaaaag
    10141 acgactacgg gagcgcagat aggctagaaa aaattgtttc caatcaagca tgcttcaatc
    10201 cgtaccctat tcctttcttg gtctcgataa atcctaccaa tccctgctcc tccaactttt
    10261 tacgcaaacg agccacattg acagagaggg tattatcatc aatgaaaaag tcactgttcc
    10321 aaagttcccg catcaggtcg tcacgtgcta cgatgttgcc tgcatgctca aataacacgc
    10381 gtaaaatctg gaattcattc ttggtcaaat tcaagacttg cccttgataa tgtaaatcca
    10441 tggatttggt attgaggata acaccagcat attccagcaa actctcatca cgcccaaact
    10501 cataggaacg acgcaacaag ccctgaacct tagctaaaag aacctgctgg tcaaaaggct
    10561 tggtcacaaa gtcatccgcc cccatattga ttgccatgac aatatccata gcctggtctc
    10621 tcgaagaaag aaacatgata ggtaccttgg aaatcttgcg gatttcctga caccagtgat
    10681 aaccattaaa caagggcaaa ccaatatcca tgaggaccag atgaggttcc gactgaacaa
    10741 atagactcaa aacttccata aagtcttcta ccaggaccac ttcaaatccc cattcagaga
    10801 gcattttccc aatctgttga cgaatgacct gatcatcttc tattaataaa atcttgtgca
    10861 tgcgcttctc cttttccatt attataacag atttttccat gctagatggt ctgaaactga
    10921 atttgaaata gcctgttttt agccagtaca aacaggctat gctactagct aatttgaggg
    10981 aaatttgcta agataaataa aaagaaagga gctcttatgg ccaatatttt tgactatctg
    11041 aaagatgtcg catatgattc ttattacgac cttcccttga atgagttaga cattctaacc
    11101 ttaatagaaa tcacctacct ctcctttgat aatctggtct ccacacttcc tcaacgtctt
    11161 ttagatctag cacctcaggt tccaagagat cccaccatgc ttactagcaa aaatcgcctt
    11221 caattattag atgaattggc tcaacacaag cgcttcaaaa attgcaaact ctcccatttt
    11281 atcaacgaca tcgaccctga actgcaaaag caatttgcgg ctatgactta tcgtgtcagc
    11341 ctcgatacct atctgattgt ctttcgtggg acagatgaca gtatcattgg ctggaaggaa
    11401 gatttccacc tgacctatat gaaggaaatt cctgctcaaa agcacgccct tcgctattta
    11461 aagaactttt ttgcccatca tcctaagcaa aaggttattc tagctgggca ttccaaggga
    11521 ggaaatctcg ctatctatgc tgctagccaa attgagcaaa gtttgcaaaa tcagatcaca
    11581 gcagtttata catttgatgc acctggtctc catcaagaat tgacacagac tgcgggttat
    11641 caaaggataa tggatagaag caagatattc attccacaag gttccattat cggtatgatg
    11701 ctggaaattc ctgctcacca aatcatcgtt cagagtactg ccctgggtgg catcgcccag
    11761 cacgatacct ttagttggca gattgaggac aagcacttcg tccaactgga taagaccaac
    11821 agtgatagcc agcaagtaga cacaaccttt aaagaatggg tggccacagt ccctgacgaa
    11881 gaacttcagc tctacttcga cctcttcttt ggcactattc ttgatgctgg tattagctct
    11941 atcaatgact tggcttcctt aaaggcgctt gaatacattc atcatctctt tgtccaagct
    12001 caatccctca ctccagaaga aagagaaacc ttgggtcgcc ttacccagtt attgattgat
    12061 actcgttacc aggcatggaa aaatagataa tactcttgaa aattaaatgt atacaaaaca
    12121 aaagacctag aatacatact ttcatgtgca ttctaagtct ttttaaatag aatctaatag
    12181 tcaataaaaa tcaaagagca ttgagagata atggggcttg gaacgtccct ctcgcttcaa
    12241 caaaatgacc ccattataga ttaaaaagat gccacttaga aaaagcaaaa aaggaagtaa
    12301 gacaaaggca aatatataaa aagctaactg aacattctcg tatccatttt tataaaaaag
    12361 gtaggataga taaaaataac ttgaaatgag ggataataaa aataatactg gattccacaa
    12421 acttctatta tccttccaaa atgacactat aaaggctaat acaattccta taacgagata
    12481 catttcttac tcctttaata gctacatttt atcataatta tccaaagaaa aaagagggca
    12541 tttatccctc ttaatccttc atctgactct ctgcatcggc cacgactttt tctagactgg
    12601 tttgaccaag ttctgcctcc atagtcaact gaattctctc caatttttga tccaaaacat
    12661 catgaatatg agctcctaca gggcaatttg gattcggatt gtcatggaaa ctgaagagtt
    12721 gacctgtctt accaagacat tcgaccgcct gataaacatc taaaagacta atatccttaa
    12781 ggtccttgac aatctctgtt ccgcccgttc cacgcgctac tgaaatcagc tctgccttct
    12841 tcaactggga caagatcttt ctgataatga caggattgac cccgacacta gcagccagaa
    12901 aatcactggt caccttgctt tccttcccct cgagggcaat gattatcagc atatgagtcg
    12961 caatggtaaa tctacttgga atttgcatcc tcttctcctt tttacgaggc taccctgcct
    13021 ctactcttct ttttctatta ttataccctt tttagttgta atgtcaatcg ttaccacttt
    13081 tcaaccagtc gtctaactcc cgatcgcagc cctctttctg agccaattct ctcaaaaatt
    13141 cctgatgatg agtatggtgg atcccattga ccagactttc atagtaaacc tcaaaatagg
    13201 gaagtctcag gtctttagcc agctgcaatt cagctgctac atcgtagtct acccgtcgga
    13261 agtccatatc taccaggcct ttgtcatcaa actccaaaat catatactgg gcccgcaagt
    13321 ccttccgtag ctgagcgtcc aaaaagaaag gttggccaat cgaacccgga ttgacaatca
    13381 attgcccacc agtcccgtaa cgaagcaact gctggtgaat atgtccataa acagcaatat
    13441 cacagggagg atgagtcacc aagcggtcaa actcctcttg tttgccagta tgaatcaact
    13501 ctcgccccca gttcttatca ggcagatgat ggctaattcc caccgtcaaa tccccaaact
    13561 gacgatgaat ttgaagaggt tgattgtgga gcacttcaat ttcttctagg gaaatttcct
    13621 ctaaaacata ctggcactgg cgcaagagat agcgttgact ggggcgagta ctgtccaatt
    13681 ccttacggac accatgccaa agactgtctt cccagtttcc caaaactcta gccgtaatcg
    13741 gtagttgatc caacaagtcc aaaatccttc tacgccctgt ccctggcatg agaatatctc
    13801 ccaaaagcca gtattcatcc actcctatct gccgagcatc tgccaaaaca gcctccaagg
    13861 cggtggtatt tccatgaata tctgaaagaa gagctatttt cgtcatatcc atctcctcgt
    13921 tttttctctt gcaataagta taacataaaa agtcacagct agagaaatct agcttttttt
    13981 gatatactag ataaagatat tagacaagag gaaacgaatg accccaaaca aagaagacta
    14041 tctaaaatgt atttatgaaa ttggcataga cctgcataag attaccaaca aggaaattgc
    14101 ggctcgcatg caagtctctc cccctgccgt aactgaaatg atcaaacgaa tgaaaagtga
    14161 aaatctcatc ctaaaggaca aggaatgtgg ctatctactg actgacctcg gtctcaaact
    14221 ggtctctgag ctctatcgta agcaccgctt gattgaagtt tttctagttc atcatttaga
    14281 ctatacaagt gaccagattc acgaggaagc tgaggtcttg gaacacactg tctctgacct
    14341 gttcgtggaa agactagata aactgctagg tttccctaaa acctgccccc acgggggaac
    14401 tattcctgcc aagggagaac tactcgttga aatcaataac ctcccactag ctgatatcaa
    14461 ggaagctggc gcctaccgcc tgactcgggt gcacgatagt tttgacattc tccattatct
    14521 ggacaagcac tcacttcaca tcggtgacca gctccaagtc aagcagtttg atggcttcag
    14581 caataccttc actatcctca gtaacgacga ggatttacaa gtgaatatgg acattgcaaa
    14641 acaactctat gtcgagaaaa tcaactaatt tctcaagtcc cctaccaacc ctgaaagttt
    14701 ta
//
LOCUS       DAVFER010000052        14512 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1105170250
            SAMEA2167659-rid19724873.denovo.052, whole genome shotgun sequence.
ACCESSION   DAVFER010000052 DAVFER010000000
VERSION     DAVFER010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2167659
            Sequence Read Archive: ERR388902
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14512)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14512)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928716.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928716.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 04:07:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,118
            CDSs (total)                      :: 2,073
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 120
            CDSs (without protein)            :: 120
            Pseudo Genes (ambiguous residues) :: 0 of 120
            Pseudo Genes (frameshifted)       :: 67 of 120
            Pseudo Genes (incomplete)         :: 47 of 120
            Pseudo Genes (internal stop)      :: 34 of 120
            Pseudo Genes (multiple problems)  :: 23 of 120
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14512
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2167659-rid19724873.denovo.052"
                     /strain="1105170250"
                     /db_xref="taxon:1313"
     gene            <1..157
                     /locus_tag="VU534_001790"
     CDS             <1..157
                     /locus_tag="VU534_001790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU1514335.1"
                     /translation="YSNAKLEATNNLIKLIKRNAFGFRNFENFKKRIFIALNIKKERT
                     KFVLSQA"
     gene            complement(207..917)
                     /gene="deoD"
                     /locus_tag="VU534_001791"
     CDS             complement(207..917)
                     /gene="deoD"
                     /locus_tag="VU534_001791"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HEU1514336.1"
                     /translation="MSIHIAAQQGEIADKILLPGDPLRAKFIAENFLDDAVCFNEVRN
                     MFGYTGTYKGHCVSVMGTGMGMPSISIYARELIVDYGVKKLIRVGTAGSLNEEVHVRE
                     LVLAQAAATNSNIVRNDWPQYDFPQIASFDLLDKAYHIAKKLGMTTHVGNVLSSDVFY
                     SNYFEKNIELGKWGVKAVEMEAAALYYLAAQYHVDALAIMTISDSLVNPDEDTTAEER
                     QNTFTDMMKVGLETLIAE"
     gene            complement(1571..2083)
                     /locus_tag="VU534_001792"
     CDS             complement(1571..2083)
                     /locus_tag="VU534_001792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001275913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin"
                     /protein_id="HEU1514337.1"
                     /translation="MSAQITINHKKARYVRIELEGYNALSLAEVEVFCFIATNAETAT
                     QVSKPVQPISQTPVKDKTLTIQHSGAYIARYSITWEEVPVDKDGNQVVRSHSWEGSGR
                     NQTAGFVLNLPIKENMRNLRVKIEKKTGLLWNRWQTIYENRPILAQPHRKITHWGTTL
                     NSKVSDDDVL"
     gene            complement(2108..3088)
                     /locus_tag="VU534_001793"
                     /pseudo
     CDS             complement(2108..3088)
                     /locus_tag="VU534_001793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855254.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="discoidin domain-containing protein"
     gene            complement(3564..4373)
                     /locus_tag="VU534_001794"
     CDS             complement(3564..4373)
                     /locus_tag="VU534_001794"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HEU1514338.1"
                     /translation="MTFLNKIHETATFLKEKGIAAPEFGLILGSGLGELAEEIENPVV
                     VDYAEIPNWGRSTVVGHAGKLVYGELAGRKVLALQGRFHFYEGNPLEVVTFPVRVMKV
                     LGCEGVIVTNAAGGIGFGPGTLMAISDHINMTGQNPLMGENLDDFGPRFPDMSRAYTP
                     EYRATAHEVAKKLNIKLDEGVYIGVTGPTYETPAEIRSYKTLGADAVGMSTVPEVIVA
                     AHSGLKVLGISCITNFAAGFQEELNHEEVVEVTERVKGDFKGLLKAILAEL"
     gene            complement(4389..4931)
                     /locus_tag="VU534_001795"
     CDS             complement(4389..4931)
                     /locus_tag="VU534_001795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1697 domain-containing protein"
                     /protein_id="HEU1514339.1"
                     /translation="MTRYALLVRGINVGGKNKVVMAELRQELTNLGLEKVESYINSGN
                     IFFTSIDSKAQLVEKLETFFAVHYPFIQSFSLLSLEDFEAELENLPAWWSRDLARKDF
                     LFYTEGLDVDQVIATVESLELKDEVLYFGKLGIFWGKFSEESYSKTAYHKYLLKVPFY
                     RHITIRNAKTFDKIGQMLKK"
     gene            complement(4933..6144)
                     /locus_tag="VU534_001796"
     CDS             complement(4933..6144)
                     /locus_tag="VU534_001796"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HEU1514340.1"
                     /translation="MSKFNRIHLVVLDSVGIGAAPDANNFVNAGVPDGASDTLGHISK
                     TVGLNVPNMAKIGLGNIPRETPLKTVAAESNPTGYATKLEEVSLGKDTMTGHWEIMGL
                     NITEPFDTFWNGFPEEILTKIEEFSGRKVIREANKPYSGTAVIYDFGPRQMETGELII
                     YTSADPVLQIAAHEDIIPLDELYRICEYARSITLERPALLGRIIARPYVGEPGNFTRT
                     ANRRDLAVSPFFPTVLDKLNEAGIDTYAVGKINDIFNGAGINHDMGHNKSNSHGIDTL
                     LKTMGLAEFEKGFSFTNLVDFDALYGHRRNAHGYRDCLHEFDERLPEIIAAMRENDLL
                     LITADHGNDPTYAGTDHTREYIPLLAYSPAFKGNGLIPVGHFADISATVADNFGVETA
                     MIGESFLDKLV"
     gene            complement(6158..6841)
                     /gene="rpiA"
                     /locus_tag="VU534_001797"
     CDS             complement(6158..6841)
                     /gene="rpiA"
                     /locus_tag="VU534_001797"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HEU1514341.1"
                     /translation="MENLKKMAGITAAEFIKDGMVVGLGTGSTAYYFVEEIGRRIKEE
                     GLQITAVTTSSVTSKQAEGLNIPLKSIDQVDFVDVTVDGADEVDSQFNGIKGGGGALL
                     MEKVVATPSKEYIWVVDESKLVEKLGAFKLPVEVVQYGAEQVFRHFERAGYKPSFREK
                     DGQRFVTDMQNFIIDLALDVIENPIAFGQELDHVVGVVEHGLFNQMVDKVIVAGRDGV
                     QISTSKKGK"
     gene            complement(7139..7978)
                     /locus_tag="VU534_001798"
     CDS             complement(7139..7978)
                     /locus_tag="VU534_001798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="HEU1514342.1"
                     /translation="MKVIDQTLLEKVIIERSCTSHKGDYGRLLLLGGTYPYGGAIIMA
                     ALAAVKSGAGLVTVGTDRENIPALHSHLPEAMAFSLQDQQLLQEQLEKAEVVLLGPGL
                     RDDTFGENLVKQVFASLKKNQILIVDGGALTILARTSLLFPSNQLILTPHQKEWEKLS
                     GIAIEKQNEGTTSSALTSFPQGTILVEKGPATRIWQVGQSDYYQLKVGGPYQATGGMG
                     DTLAGMIAGFAGQFRQASLYERVAVATHLHSAIAQELSQENYVVLPTEISNCLPKVMK
                     RYV"
     gene            complement(7993..8814)
                     /locus_tag="VU534_001799"
     CDS             complement(7993..8814)
                     /locus_tag="VU534_001799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000601058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATPase"
                     /protein_id="HEU1514343.1"
                     /translation="MILKIYNGEYSLQWDGIYYLALIDYPNIQEWELEKIAKFIAYEK
                     LHKRQTSIECADSCLKKEILDYICQHPFLPPFTPTDKRVASTYDLHKRLVTSDYCSHT
                     TTIDAAISIFKTGRLLSAVKAFGRDAEELVLDSRNAASDPIDYFDYVMLGWSNTSSGY
                     RLAMERLLGRAPSEKELQDKFIPGVSFHFIYTDLIKVPGYIFDGYHAVKIKDMLNLLS
                     ELYICIIPTHNKSQFENIIPTKIQDRVYYLDYAGEDLEEWTKKVYQVVLKQSDKG"
     gene            complement(8952..9809)
                     /locus_tag="VU534_001800"
     CDS             complement(8952..9809)
                     /locus_tag="VU534_001800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000192112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="HEU1514344.1"
                     /translation="MTQIIDGKALAAKLQGQLAEKTAKLKEETGLVPGLVVILVGDNP
                     ASQVYVRNKERSALAAGFRSEVVRVPETITQEELLDLIAKYNQDPAWHGILVQLPLPK
                     HIDEEAVLLAIDPEKDVDGFHPLNMGRLWSGHPVMIPSTPAGIMEMFHEYGIDLEGKN
                     AVVIGRSNIVGKPMAQLLLAKNATVTLTHSRTHNLSKVAAKADILVVAIGRAKFVTAD
                     FVKPGAVVIDVGMNRDENGKLCGDVDYEAVAPLASHITPVPGGVGPMTITMLMEQTYQ
                     AALRTLDRK"
     gene            complement(9988..10722)
                     /locus_tag="VU534_001801"
     CDS             complement(9988..10722)
                     /locus_tag="VU534_001801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEU1514345.1"
                     /translation="MTETLIKIENLHKSFGKNEVLKGINLEIKRGEVVVIIGPSGSGK
                     STLLRSMNLLEEATKGKVIFEGVDITDKKNDLFAMREKMGMVFQQFNLFPNMTVMENI
                     TLSPIKTKGDSKAVAEKRAQELLEKVGLPDKADAYPQSLSGGQQQRIAIARGLAMEPD
                     VLLFDEPTSALDPEMVGEVLAVMQDLAKSGMTMVIVTHEMGFAREVADRVIFMADGVV
                     VEDGTPEQIFEQTQGQRTKDFLSKVL"
     gene            complement(10722..11405)
                     /locus_tag="VU534_001802"
     CDS             complement(10722..11405)
                     /locus_tag="VU534_001802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001011621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEU1514346.1"
                     /translation="MNFSFLPKYLPYFNYGAVVTILISICVIFLGTILGVVLAFGQRS
                     KFKPLVWLANLYVWIFRGTPMMVQIMIAFALMHINAPTIQIGILGVDFSRLIPGILII
                     SMNSGAYVSETVRAGINAVPKGQLEAAYSLGIRPKNAMRYVILPQAVKNILPALGNEF
                     ITIIKDSSLLSAIGVMELWNGATTVSTTTYLPLTPLLFAAFYYLIMTSILTVALKAFE
                     KHMGQGDKK"
     gene            11595..11825
                     /locus_tag="VU534_001803"
     CDS             11595..11825
                     /locus_tag="VU534_001803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005592360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkuJ family protein"
                     /protein_id="HEU1514347.1"
                     /translation="MESHLVRIINRLEAMANDGGNLKRNFEREGVVVAEVAYSHDEEN
                     GPIFTLRDVEDRETYTFDSIDLIAMEIYELLY"
     gene            12054..14312
                     /locus_tag="VU534_001804"
     CDS             12054..14312
                     /locus_tag="VU534_001804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEU1514348.1"
                     /translation="MLCQNCKINDSTIHLYTNLNGKQKQIDLCQNCYKIIKTDPNNSL
                     FKGMTDLNNRDFDPFGDFFNDLNNFRPSSNTPPIPPTQSGGGYGGNGGYGSQNRGSAQ
                     TPPPSQEKGLLEEFGINVTEIARRGDIDPVIGRDDEIIRVIEILNRRTKNNPVLIGEP
                     GVGKTAVVEGLAQKIVDGDVPHKLQGKQVIRLDVVSLVQGTGIRGQFEERMQKLMEEI
                     RKREDIILFIDEIHEIVGAGSASDGNMDAGNILKPALARGELQLVGATTLNEYRIIEK
                     DAALERRMQPVKVDEPTVDETITILKGIQKKYEDYHHVQYTDAAIEAAATLSNRYIQD
                     RFLPDKAIDLLDEAGSKMNLTLNFVDPKVIDQRLIEAENLKSQATREEDFEKAAYFRD
                     QIAKYKEMQKKKITDQDTPSISEKTIEHIIEQKTNIPVGDLKEKEQSQLIHLAEDLKS
                     HVIGQDDAVDKIAKAIRRNRVGLGTPNRPIGSFLFVGPTGVGKTELSKQLAIELFGSA
                     DSMIRFDMSEYMEKHSVAKLVGAPPGYVGYDEAGQLTEKVRHNPYSLILLDEVEKAHP
                     DVMHMFLQVLDDGRLTDGQGRTVSFKDAIIIMTSNAGTGKTEASVGFGAAREGRTNSV
                     LGELGNFFSPEFMNRFDGIIEFKALSKDNLLQIVELMLADVNKRLSSNNIRLDVTDKV
                     KEKLVDLGYDPKMGARPLRRTIQDYIEDTITDYYLENPSEKDLKAVMTSKGNIQIKSA
                     KKAEVKSSEKEK"
BASE COUNT         4356 a         3246 c         2615 g         4295 t
ORIGIN      
        1 ctattctaat gccaaactgg aagcgaccaa taatctcatc aaacttatca agcgcaatgc
       61 ctttggtttt cggaactttg aaaacttcaa aaaacggatt tttatcgccc tgaatatcaa
      121 aaaagaaagg acgaaatttg tcctttctca agcttagctt tttttcaacc cactacagtt
      181 gacaaagagc ccctttttgg ctataattat tctgcaatca aggtttccaa accaaccttc
      241 atcatatcag tgaaggtatt ttgacgttct tctgcagttg tgtcttcgtc tggattgacc
      301 aagctatcag agatggtcat gatagctagc gcatcaacat ggtattgggc agcaagatag
      361 taaagagctg ctgcttccat ttccacagcc ttgactcccc atttaccaag ctcgatattc
      421 ttttcaaagt aatttgagta aaagacatca gatgacaaaa cgttcccaac gtgagtagtc
      481 ataccaagtt ttttggcgat atggtaggct ttatcaagca aatcaaagct agcaatttgt
      541 ggaaaatcgt actgtggcca gtcattacga acgatgtttg agttggttgc agccgcctgc
      601 gccaaaacta attcacgaac atgaacctct tcattcaaag aacctgcagt tcccacacga
      661 atcaatttct tcacaccgta gtctacgatt aactcacgcg cataaatcga aatagatggc
      721 attcccatcc cagttcccat gacagataca cagtgaccct tgtaagtacc agtgtaacca
      781 aacatgttac gcacttcgtt aaaacaaaca gcatcatcaa ggaaattctc cgcaataaac
      841 ttagcacgaa gaggatcccc aggaagaaga attttatcag caatttcacc ctgctgagca
      901 gcaatatgga tagacataat ttatgataca aagagcgaga agaaaacgac tgaaaattag
      961 gaacctgacg agaaatcctg atttttcagt cagattatct attttccgag ttttccgctc
     1021 gtgttcaaat caaaacacac gctctacctt tctttatttt atattttata ttgagaaaga
     1081 taccaaaccc atcaaaaagc gaagggaaaa taggagttgg gcgcagtgag cgatgctcgc
     1141 tagatcaact atctttttcc cactactttt agggtggggt caattccttt cttaattttg
     1201 atttagagga gagtcgcccg tattcagttc agcgaataca gtttacccat cctttcgttt
     1261 ttgtttttag aaaagttttc tactcgtgtt ctaatttgaa cacgcgctct acctttctgt
     1321 ttatactctt cgaaaatctc ttcaaaccac gtcaacgtcg ccttggatta tatatgtgac
     1381 tgacttcgtc agtcttatct acaacctcaa agcagtgctt tgagcaacct gcggctagtt
     1441 tcttagtttg ctctttgatt ttcattgagt attaattttg ttctttcata gagagctacc
     1501 tgagtcctat tcaagctcag gtagtacttt cttataaact agacaaacta actgtcattc
     1561 taccatcaga ttacaagaca tcatcgtcac tcaccttgga attcaatgtc gtaccccaat
     1621 gggtaatttt acggtggggt tgagctaaaa ttggtctgtt ttcatagatt gtttgccatc
     1681 tattccatag taggcccgtc tttttctcaa tcttaactcg cagatttctc atattttctt
     1741 tgattgggag gttgaggaca aaacctgcag tctggttgcg accgcttcct tcccaagaat
     1801 gactacgaac aacttggttt ccatctttat ctactggaac ttcttcccaa gttatggagt
     1861 agcgggcaat gtaagctcca ctgtgttgaa ttgtcaatgt tttatccttc acaggagtct
     1921 gactgattgg ttgaactggc ttagaaactt gtgtcgccgt ttcagcattc gtagctataa
     1981 agcagaaaac ttcaacttct gcaagactga gggcattata gccttctagc tcaatccgaa
     2041 catagcgcgc ttttttatgg ttaatcgtaa tttgtgctga cacatcttta ggagatgtta
     2101 tacgttttca ctcaatttct ttaccagaac tgtctaaaag aatgacatca aagtttgcca
     2161 atctatcctg ggcagtgtct gttcggttgt aaatattgat ttggcgaatg gtttcttctt
     2221 tagccaaatc tacttgccac caaggcttag attggaagtt tgtatgagtg acagaattgt
     2281 gaccatagtt accatcgact ttgccatcca cagctcttct agcatctcct ccgaaagctg
     2341 tcgaactttg agtaacctgt tttcctgagg caatattttc cattggttca gcgcttggtt
     2401 gactagaaga tcgaggcaga gcctgtttct taaagaatcg cactttatcc aatttcggat
     2461 cacgataacc atgtttatcc aaggtagctt gtttaccaat attaaagtta ggaatatcat
     2521 tcattggact ttcaaaatag ccacgagaac ggtgtttaaa gcgtgaatta cctgtaaatg
     2581 taacaatatc acgattatta tgaatcaagg gagtcacaac attgtcatta tcaaccacat
     2641 aatgcttaat ttttccacta acagctaatt tacgactttc caaaccaaca tcccagaaac
     2701 cattcttagc attccaaaca gttctggaag taatcacttt aggagcactg aaagttgtca
     2761 ctttcctcaa tacatggtta taaaaatcag gatatttttg gtaagcttca accgctgcaa
     2821 tctgagctag gtaacatcca agagaatgac ctgtcatata caacttagta atacttatat
     2881 ccttggctaa ttccccaaca accttgcgga tatcatccgc ttgagctggt tatgttatct
     2941 ctacttttga ctcttccctt ttgttttcaa gaacttcact tgcttccgga agcgtttgag
     3001 gagctagtct tggctcctct ctaagaggag tttctagttt tggagcatca ttttctgact
     3061 ctttcaattc ctccttagaa tctagcacac ctattaccac ttcagatgtt acatcttgct
     3121 ttacttcatt ggctgaaatt ccagctggag ctagaaatca aagccgacta caacagatac
     3181 aactccgata cttaattttt tatgccaaag cgcataattc gttgaccaat tttcattatt
     3241 tcttatcttt cttttcgttt atttacaagc agactcaagc gaaatctcat tgtgctatat
     3301 atgataagac tgagaaattc agaaagtcaa ttcattctca tctctcctta tcatactagt
     3361 ctgcttggct aggaagctaa tgctagtatc ctagaatctt gtctttcaca atgctggcta
     3421 tcagatcaga catacctatt cttccgcttc tttcagttat aagagcagga agaagctcat
     3481 agtattcctc tgtttcttct ttaatccgga taggcagtca atcctgaaaa aacagaggca
     3541 ctcccccttt taaatctttt ttcttacaat tcagcaagaa tcgctttaag caagcctttg
     3601 aaatcacctt taacacgttc agtcacttct acaacttctt cgtgattgag ttcttcttgg
     3661 aaaccggccg caaagttagt gatacatgaa attcccagaa ctttcaagcc agagtgggct
     3721 gccacgataa cttcaggaac cgtagacata ccaactgcat ctgctcccag tgtcttatag
     3781 gaacgaattt ctgctggtgt ttcataagtc ggaccagtaa ctccgatata gacaccttca
     3841 tcaagcttga tattaagttt tttagccact tcatgggcag tggcacggta ttctggtgtg
     3901 taggccctag acatatctgg gaaacgtggg ccaaagtcat ccaagttttc acccatcaat
     3961 ggattttgcc ccgtcatgtt gatatggtct gagatagcca tcaaggtacc aggaccaaat
     4021 ccgataccgc cagctgcatt ggttacaata acaccttcac atccaagaac tttcatcaca
     4081 cgaactggga aagtcaccac ttccagagga ttcccttcat agaaatggaa acgcccttga
     4141 agagccaaga ccttgcgacc tgccagttca ccatatacca atttaccagc atgaccgact
     4201 actgttgaac ggccccagtt tggaatctca gcgtagtcta ctacaactgg attttcgatt
     4261 tcttctgcca attctccaag tcctgatcca aggattagac cgaactcagg ggctgcaatt
     4321 cccttttctt tcaggaaagt agcagtttca tggattttgt ttaaaaatgt cattgtgtgt
     4381 ctcctttatt atttttttag catttgacca attttgtcaa aggttttagc attacgaata
     4441 gtaatgtggc ggtagaaagg caccttcagc aagtacttat gataggcagt cttagaatag
     4501 gattcttcag aaaatttccc ccagaaaatc ccaagttttc caaaataaag cacttcatct
     4561 ttcagctcta aactttcaac tgtcgcgatg acttggtcca catccaaacc ctcagtgtaa
     4621 aagagaaaat cttttcgtgc caagtctctg ctccaccaag ctggtagatt ttcaagttcc
     4681 gcctcaaagt cctctagact cagtaaagaa aagctctgaa taaatggata atggactgca
     4741 aagaaagtct ctagcttttc aaccaattgg gctttggaat ctatcgaagt aaagaaaata
     4801 ttgccactat tgatgtagct ctcaaccttt tccagtccca agtttgtcaa ttcttgacga
     4861 agctccgcca tgacgacctt attcttacca ccaacattga tacctctcac cagcaaagca
     4921 tagcgcgtca tcttatacca atttatctaa gaaactttcc ccaatcatag cagtttccac
     4981 accaaagtta tcggcaacag tcgctgaaat atctgcaaaa tgtcctactg gaatgagacc
     5041 atttccttta aaggcagggc tataggccaa caatggaata tattcccgag tgtgatccgt
     5101 tcctgcatac gttgggtcat ttccatggtc cgcagtaatc aagagaaggt cattctctct
     5161 catagctgcg ataatttcag gtaagcgttc atcaaactca tgcaagcaat cacggtaacc
     5221 gtgagcatta cgacgatggc cgtaaagggc atcaaagtca actaggtttg tgaatgagaa
     5281 tcctttttca aactcagcaa gtcccatagt cttcaatagt gtatcaattc catgactatt
     5341 tgacttgttg tgacccatgt catggttgat accagcaccg ttaaagatat cgttgatttt
     5401 acccacagca taagtatcga taccagcctc attcaattta tccaaaacag ttgggaaaaa
     5461 tggagataca gccaagtcac gacggtttgc cgtacgagtg aagttacctg gttcacctac
     5521 ataagggcga gcaatgatgc gaccaagaag ggcaggacgc tcaagggtaa tcgaacgagc
     5581 gtattcacag atacggtaca attcatccaa aggaataatg tcttcgtggg cagcaatctg
     5641 caaaacaggg tcagctgaag tatagataat caactctcca gtttccatct gacgtggtcc
     5701 aaaatcatag ataacagccg ttcctgaata aggtttgttg gcttcacgaa taaccttgcg
     5761 tcctgagaat tcttcgattt ttgtcaggat ttcttctggg aatccgttcc agaaagtatc
     5821 gaaaggctca gtaatgttga gtcccatgat ttcccagtgt ccagtcatag tatccttacc
     5881 aagagatact tcctctaatt ttgttgcata tccagttgga ttgctttcag ctgctacagt
     5941 cttaagagga gtttcacgag gaatatttcc aagacctatt ttagccatgt ttgggacatt
     6001 caaaccaact gtttttgaaa tgtgtcccag tgtgtcagaa gctccatctg gaacccctgc
     6061 attgacaaag ttattagcat ctggtgctgc accgattcct acagaatcca gtaccaccaa
     6121 atgaatacga ttaaatttag acatcttatg cccccttcta ttttcctttt tttgaagttg
     6181 aaatctgaac tccatctcgt ccagcaacga ttaccttatc caccatttgg ttgaataaac
     6241 catgctccac aacaccaacg acatggtcca attcttgtcc aaaagcaatt ggattttcaa
     6301 tgacatccaa ggcgaggtca atgataaaat tctgcatatc ggtcacaaaa cgttggccgt
     6361 ctttttcacg gaaacttggt ttgtagccag ctcgttcaaa atgacgaaag acctgctctg
     6421 caccatactg aaccacttct actggcaatt taaaagcacc tagtttttcg accagcttgc
     6481 tttcatccac cacccaaatg tattcttttg atggtgttgc gaccaccttt tccatgagaa
     6541 gggcaccacc accgcctttg attccattaa actgactatc cacttcatcc gccccgtcga
     6601 ctgtcacatc gacaaagtct acttggtcaa tagacttgag cgggatattg agcccttcag
     6661 cctgtttact ggtcacacta gaagtcgtca cagctgtaat ctgcaagcct tcttccttga
     6721 ttcgacgacc gatttcttcg acaaaataat aggcagtaga acctgttcct agccctacaa
     6781 ccatcccatc cttgataaat tcagcagccg tgatacctgc cattttcttc agattttcca
     6841 ctcaaacacc tccattaaag agctacctct attataccat gtaaaggctt ttatttcatc
     6901 taaaagtacc tttagaatac tgcttattta tccttgaaat tgaatttttt taataaaagt
     6961 agagctctaa caaatcaatt taagtacgga tgtaaaccaa atcaactcta acaaaaatag
     7021 atttacaaga gtaaaaaaac gaacaaattt agtttcttag caagaagaat actaaacgtt
     7081 cgttttttgt gaattaagaa taatgataca aattatcaac attttttgtc taactatttt
     7141 agacatatct tttcattact ttaggaagac aattactaat ttccgtcggc aagaccacat
     7201 aattttcttg agatagttct tgggctatgg ctgaatgaag atgggttgct actgccacac
     7261 gttcgtagag actggcctgt cgaaattggc ctgcaaatcc tgcaatcatt ccagccagtg
     7321 tatcacccat accaccagtc gcctgatagg gaccgccaac ctttaactgg taataatcag
     7381 actggccaac ttgccaaata cgagtagctg gacctttctc taccaaaatt gttccttgag
     7441 ggaaagaagt cagggcacta gatgttgtac cttcgttttg cttttcaata gcaataccag
     7501 acagtttttc ccattctttt tggtggggag ttaagataag ctggttagat ggaaacaaca
     7561 aacttgtcct agcaaggatg gttaaggccc ctccatctac aatcaaaatc tgattctttt
     7621 ttaagctagc aaagacctgt tttacaagat tttctccaaa cgtatcgtct cgtaaaccag
     7681 gccccagcaa gacaacttct gccttctcca attgctcttg taacaattgc tgatcttgca
     7741 gagaaaaggc catagcctca ggcaaatggc tgtgtagagc agggatattt tccctgtccg
     7801 ttccaacggt taccaatcct gcaccgcttt ttacagctgc taaagcagcc atgatgatgg
     7861 caccaccata aggataagtc ccaccaagca acagcagacg accgtagtct cctttatgac
     7921 ttgtacaaga acgttcaata atgacttttt ctagtaaggt ttgatcaatc actttcatcg
     7981 ttttttcctc aactatcctt tatctgattg ttttaaaaca acttgataga ctttcttagt
     8041 ccactcttct aagtcttctc cagcatagtc aagataatac accctatctt gtattttggt
     8101 tggaataata ttttcaaatt ggctcttatt atgagttgga ataatgcaaa tatacaactc
     8161 acttaataaa ttaagcatgt ccttaatttt tacagcatgg taaccatcaa aaatataacc
     8221 aggaacttta atcaaatctg tatagataaa atgaaaactt actccaggaa taaacttgtc
     8281 ttgtaattct ttctctgaag gagctcgacc taataaacgc tccatcgcca atcgataacc
     8341 agaacttgta tttgaccacc ctaacatgac atagtcaaaa taatctatcg gatcagatgc
     8401 agcatttcga ctatccaaaa ccaactcctc agcatctcgc ccaaaggctt tcacagcaga
     8461 taaaagacga ccagttttaa aaatagaaat cgctgcatct atagtcgtag tatgactaca
     8521 gtagtctgaa gtcactaacc tcttatgtag gtcataagtc gaggctactc ttttatctgt
     8581 aggagtaaat ggtggcagaa agggatgctg acagatgtaa tctaaaattt ctttttttaa
     8641 acaagaatca gcacactcaa tacttgtttg acgtttatga agtttttcgt aagctataaa
     8701 tttagcaatt ttttctaatt cccactcttg aatatttgga taatcaatta gtgctaagta
     8761 gtatattcca tcccattgta aactatattc cccattataa atttttaaaa tcatctaatc
     8821 acctcactcc attatacaac aaaaaggagg cgcaaacctc cttttataaa cttatttcta
     8881 aaatttaata ttcatttcta tcattttaga tatagctata gaaaatacac tttcctcaga
     8941 aaatttttat cttattttct atccaatgtc ctaagtgctg cctgataggt ttgctccatc
     9001 agcatagtaa tggtcatagg accgacacct ccagggactg gcgtaatgtg gctagcaagt
     9061 ggggcaaccg cctcataatc aacatcccca cagagcttac cattttcatc gcggttcatc
     9121 ccaacgtcaa tgactaccgc acctggtttg acaaagtcag cagtcacaaa cttggcacga
     9181 ccgattgcaa caaccagaat atctgctttt gcagccacct tggaaagatt atgagtacgt
     9241 gagtgagtca aggttactgt tgcattcttt gccaaaagaa gctgggccat aggttttccg
     9301 acaatattgg atcgaccgat gacgactgca tttttacctt ccaagtcaat cccatattca
     9361 tggaacattt ccataattcc tgccggtgtc gaaggaatca tgactggatg accagaccaa
     9421 agacgcccca tgtttagagg atggaaacca tccacatcct tttctgggtc aatagccaat
     9481 agaaccgcct cttcatcaat gtgttttggt aatggcaact gaaccaaaat cccatgccaa
     9541 gctggatcct gattgtattt agcaatcagg tctaacaatt cctcttgagt aatggtctct
     9601 ggaacccgta ctacttcgct acggaaacca gccgcaaggg ctgacctctc cttgttgcga
     9661 acgtagactt ggctggctgg attgtcccca accaaaatca ctaccaaacc aggcactaga
     9721 cctgtttctt cctttaattt tgcagtcttt tcagccaact gcccctgcaa tttggccgct
     9781 aaagctttcc catcaataat ctgtgtcata tcacttctct tttcttacaa atatctttaa
     9841 ttataccaaa aaatacaatg tagctctaac acttctttcc taggcaatcc tatagcttta
     9901 aactataaga aaaagctctg gttgagcttt tcactaatct tctctttaac gtttaaagct
     9961 ggctacaaat agctaaacaa agctaactta taaaacctta ctcaagaagt ctttagtcct
    10021 ttgtccttgg gtttgttcaa aaatctgctc aggtgttccg tcttcaacaa ccacaccgtc
    10081 tgccataaag atgacacgat ctgccacctc acgggcaaat cccatctcat gtgttacgat
    10141 aaccatggtc attcctgact tggctagatc ttgcataaca gccagaactt ctccaaccat
    10201 ctcaggatct agggctgaag ttggctcgtc aaagagcaaa acatctggtt ccatagccaa
    10261 cccacgcgcg atggcaatcc gctgttgctg gccacctgac aaactctgtg gataagcgtc
    10321 tgccttatct ggcaaaccaa ctttttccaa aagttcctga gctcttttct ctgcaacggc
    10381 cttactgtca cctttggtct tgatagggga caaggtgata ttttccatca cagtcatatt
    10441 aggaaagaga ttgaattgtt gaaaaaccat gcccatcttc tcacgcatgg caaacaggtc
    10501 attcttcttg tccgtaatat cgactccctc aaagataacc ttccccttgg ttgcttcttc
    10561 caacaaattc atagagcgaa gcaaggtaga tttcccgctc cctgaaggac cgatgataac
    10621 gacaacttct cctcttttaa tctcgaggtt gatgcccttc aatacttcat tctttccaaa
    10681 ggatttatgt aaattttcaa tttttatcaa ggtttctgtc attatttctt atctccttgt
    10741 cccatatgtt tttcaaaagc tttcaaggct actgtcagaa tagaggtcat aatcaagtag
    10801 taaaatgctg caaataaaag tggtgttaaa ggtagatagg ttgttgtaga aactgttgta
    10861 gccccattcc acaactccat gaccccaata gctgataaga gggagctgtc cttgataatg
    10921 gtgataaatt cgttccccaa tgctggcaag atatttttga ctgcttgtgg caaaatcaca
    10981 taacgcatcg catttttagg acgaatccct agcgaataag ccgcttctag ctgacctttt
    11041 ggaaccgcat tgattccggc acgaacagtc tccgaaacat aagcaccact attcatagag
    11101 ataatcaaaa tccctggaat cagacgcgaa aaatcaacac ctaaaattcc aatctgaata
    11161 gtcggagcat tgatatgcat aagagcaaag gcaatcataa tttgaaccat catcggtgtc
    11221 ccacggaaaa tccaaacgta caagttggcc aaccaaacaa gcggtttaaa ctttgaacgt
    11281 tgcccaaaag ccaagacaac acccaaaata gttcccaaaa agataacaca gatagaaata
    11341 agaatcgtca caacagcccc atagttaaaa taaggtaaat acttaggtaa aaaagaaaaa
    11401 ttcatagtca cactgctttc taaaatagaa tactgtatga ttataacatg ttttgaatta
    11461 aaatttaaat tttttatcca atttatttaa aaatatttaa actagcagaa ttagcgagaa
    11521 atcttagttt tttctagtca agttggcctc ctttatggta aaatagtaac gataagaaat
    11581 gaaggagaat caaaatggaa tcacatttgg ttagaatcat caaccgcctt gaagcaatgg
    11641 caaacgatgg cggaaattta aaacgtaatt ttgaacgcga aggagttgtt gttgcagaag
    11701 ttgcgtacag ccacgacgaa gaaaacggcc caatctttac ccttcgtgac gtagaagatc
    11761 gcgaaacgta tacgtttgat agcattgact taatcgcaat ggaaatttac gaacttctct
    11821 actaatctaa aacaagctgg gattgtccct gcatgtctaa gtaaaatcct ttttgtctca
    11881 caaataggat ttttttatag tccaaattca caaaaatttt cattgtaaca acttctcaaa
    11941 gcttcaatct ttttacttgc tttacacccc aatcctgtta taatgagagt atagaatttg
    12001 actatttttg acctttaaac aagtcaggct aaagaaagaa atgaggtaga tgtatgcttt
    12061 gtcaaaactg taaaattaac gactcaacaa ttcatcttta caccaatctc aatggaaaac
    12121 aaaaacaaat tgacctctgt caaaactgct ataagattat caaaacagat cctaacaata
    12181 gcctcttcaa aggtatgacg gatctgaaca atcgtgactt cgatcccttt ggtgatttct
    12241 tcaatgatct aaacaatttc agaccttcta gcaatactcc tcctattccc ccaacccaat
    12301 caggtggagg ttacggtgga aacggcggtt atggttccca aaatcgtgga tctgctcaaa
    12361 ctccgccacc tagccaagaa aaaggcctgc tggaagaatt tggtattaat gtaactgaaa
    12421 ttgcccgtcg tggagacatt gaccccgtta ttgggcgcga cgatgagatt atccgtgtca
    12481 tcgagattct caatcgtaga accaagaata atcctgtcct tatcggtgaa cctggtgtcg
    12541 gaaaaacggc cgttgtcgaa ggtctagctc agaaaattgt cgatggcgat gtgccacata
    12601 aactccaagg taaacaagtc atccgtctgg atgtggttag cttagttcaa ggaacgggga
    12661 ttcgaggaca atttgaagaa cgcatgcaaa aactcatgga agaaattcgc aaacgtgaag
    12721 acatcatcct ctttatcgat gaaatccatg aaattgttgg tgctggttct gcgagtgatg
    12781 gtaatatgga cgcaggaaat atcctcaagc cagcccttgc tcgtggagaa ctgcaactag
    12841 tcggtgctac taccctcaat gaataccgta tcattgaaaa ggatgctgcc ctcgagcgtc
    12901 gtatgcagcc tgttaaagtc gatgaaccaa cggtggacga aacaatcact attctcaaag
    12961 ggattcaaaa gaaatacgaa gattaccacc acgttcaata tacagatgct gcgattgaag
    13021 cagctgcaac tctttccaat cgctacatcc aagatcgctt cttgcctgac aaggccattg
    13081 acctcctaga tgaagctggt tctaagatga acttgacctt gaattttgtg gatcctaaag
    13141 taattgatca gcgcttgatt gaggctgaaa atctcaagtc tcaagctaca cgagaagaag
    13201 attttgagaa ggcggcctac ttccgcgacc agattgccaa gtataaggaa atgcaaaaga
    13261 aaaagatcac agaccaggat actcctagca tcagcgagaa aactattgag cacattatcg
    13321 agcagaaaac caatatccct gttggtgatt tgaaagagaa agaacaatct caactcatcc
    13381 atctagccga agatctcaag tctcatgtta ttggtcaaga tgatgcagtc gataagattg
    13441 ccaaggctat tcgccgtaat cgtgtcggac ttggtacccc taaccgccca atcggaagct
    13501 tcctcttcgt tgggccaact ggtgtcggta agacagaact ttccaaacaa ctggctatcg
    13561 aactttttgg ttctgctgat agtatgattc gctttgatat gagtgaatac atggaaaaac
    13621 atagtgtggc taagttggtc ggcgctcctc caggttatgt tggctatgat gaggctggtc
    13681 aattaactga aaaagttcgc cacaatccat attctctcat ccttctcgat gaagtggaaa
    13741 aagctcaccc agatgttatg cacatgtttc ttcaagtctt ggacgatggt cgtttgacag
    13801 acgggcaagg acgcaccgtt agcttcaagg atgccatcat tatcatgacc tcaaatgcag
    13861 gtacaggaaa gaccgaagct agcgttggat ttggtgctgc tagagaagga cgtaccaatt
    13921 ctgtcctcgg tgaactcggt aacttcttta gcccagagtt tatgaaccgt tttgatggca
    13981 ttatcgaatt taaggctctc agcaaggata acctccttca gattgtcgag ctcatgctag
    14041 cagatgttaa caagcgcctc tctagcaaca acattcgttt ggatgtaact gataaggtca
    14101 aggaaaagtt ggttgaccta ggttatgatc caaaaatggg agcacgccca cttcgtcgga
    14161 ctattcaaga ctatattgag gacacaatca ctgactacta ccttgaaaat ccaagcgaaa
    14221 aagatctcaa agcagttatg actagcaagg gaaacattca gattaaatct gccaaaaaag
    14281 ctgaagttaa aagttctgaa aaagaaaaat aaatcctata aaaaaggagt agaaaatgaa
    14341 atttttctgc ttcttttttt actaaaataa ctgtaatttc ttgacagctt gccctttgtc
    14401 cattatgata tatagtagac tgaatctgaa atagtacgaa acaattgcta aaacatttat
    14461 agaaattaat tttactttcc caatcgattt gttctcatct tatttcaatc tg
//
LOCUS       DAVFER010000053        13703 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1105170250
            SAMEA2167659-rid19724873.denovo.053, whole genome shotgun sequence.
ACCESSION   DAVFER010000053 DAVFER010000000
VERSION     DAVFER010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2167659
            Sequence Read Archive: ERR388902
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13703)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13703)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928716.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928716.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 04:07:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,118
            CDSs (total)                      :: 2,073
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 120
            CDSs (without protein)            :: 120
            Pseudo Genes (ambiguous residues) :: 0 of 120
            Pseudo Genes (frameshifted)       :: 67 of 120
            Pseudo Genes (incomplete)         :: 47 of 120
            Pseudo Genes (internal stop)      :: 34 of 120
            Pseudo Genes (multiple problems)  :: 23 of 120
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13703
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2167659-rid19724873.denovo.053"
                     /strain="1105170250"
                     /db_xref="taxon:1313"
     gene            <1..930
                     /locus_tag="VU534_001805"
     CDS             <1..930
                     /locus_tag="VU534_001805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HEU1514349.1"
                     /translation="IAQKLIEKISMTDIAHQLSISTSTVIRKLNDFHFKHDFSCLPEI
                     MSWDEYAFTKGKMSFIAQDFNNLNIITVLKGRTQAVIRNHFLKYDRAVRCRVKIITMD
                     MFSPYYDLARQLFPCAKIVLDRFHIVQHLSRAMSRVRVQIMNQFHRKSHEYKAIKRYW
                     KLIQQDSRKLSDKRFYRPTFRMHLTNKEILNKLLSYSQNLKHHYQLYQLLLFHFQNKE
                     PEKFFGLIEDNLKQVHPIFQTVFKTFLKDKKKIVNTLQLPYSNAKLEATNNLIKLIKR
                     NAFGFRNFENFKKRIFIALNIKKERTKFVLSRA"
     gene            complement(981..1916)
                     /gene="dapA"
                     /locus_tag="VU534_001806"
     CDS             complement(981..1916)
                     /gene="dapA"
                     /locus_tag="VU534_001806"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HEU1514350.1"
                     /translation="MSYQDLKKCKIITAFITPFHEDGSINFDAIPALIEHLLAHHTDG
                     ILLAGTTAESPTLTHDEELELFAAVQKVVNGRVPLIAGVGTNDTRDSIEFVKEVAEFG
                     GFAAGLAIVPYYNKPSQEGMYQHFKTIADASDLPIIIYNIPGRVVVELTPETMLRLAD
                     HPNIIGVKECTSLANMAYLIEHKPEEFLIYTGEDGDAFHAMNLGADGVISVASHTNGD
                     EMHEMFTAIAESDMKKAAAIQRKFIPKVNALFSYPSPAPVKAILNYMGFEAGPTRLPL
                     VPAPEEDAKRIIKVVVDGDYEATKATVTGVLRPDY"
     gene            complement(1972..3048)
                     /locus_tag="VU534_001807"
     CDS             complement(1972..3048)
                     /locus_tag="VU534_001807"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000542485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HEU1514351.1"
                     /translation="MGYTVAVVGATGAVGAQMIKMLEESTLPIDKIRYLASARSAGKS
                     LKFKDQDITIEETTETAFEGVDIALFSAGSSTSAKYAPYAVKAGVVVVDNTSYFRQNP
                     DVPLVVPEVNAHALDAHNGIIACPNCSTIQMMVALEPVRQKWGLDRIIVSTYQAVSGA
                     GMGAILETQRELREVLNDGVKPRDLHAEILPSGGDKKHYPIAFNALPQIDVFTDNDYT
                     YEEMKMTKETKKIMEDDSIAVSATCVRIPVLSAHSESVYIETKEVAPIEEVKAAIAAF
                     PGAVLEDDVAHQIYPQAINAVGSRDTFVGRIRKDLDAEKGIHMWVVSDNLLKGAAWNS
                     VQIAETLHERGLVRPTAELKFELK"
     gene            complement(3390..3462)
                     /locus_tag="VU534_001808"
     tRNA            complement(3390..3462)
                     /locus_tag="VU534_001808"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(3427..3429),aa:Thr,seq:ggt)
     gene            complement(3562..4071)
                     /locus_tag="VU534_001809"
     CDS             complement(3562..4071)
                     /locus_tag="VU534_001809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HEU1514352.1"
                     /translation="MKKLTIRDVADIAIVAAIYVVLTVTPPLNAISYGAYQFRISEMM
                     NFMAFYNPKYIIGVTIGCMIANFFSFGLLDVFVGGGSTLVFLSLGVWLFAKYSKDYLF
                     NGLIRKDHFFFSILFSISMFTIAAELNIVAELPFFLTWFTTGIGEFASLIIGAIIIGK
                     IGRRIDLSK"
     regulatory      complement(4069..4165)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01054"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class II; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF01054"
     gene            4194..4625
                     /locus_tag="VU534_001810"
     CDS             4194..4625
                     /locus_tag="VU534_001810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HEU1514353.1"
                     /translation="MKKPIQKFFNNEILAYLFFGIVTTLVAILSRLVIYQLSHQELLA
                     TALANIIGILFAFITNDTIVFKQKKKNRLIRLVKFSLARLSTFLLDLFLTFLFVTQFP
                     HIIGQFVTENIDKINAIETIIAQIFIIIINYILSKVYIFRK"
     gene            4707..5084
                     /gene="mscL"
                     /locus_tag="VU534_001811"
     CDS             4707..5084
                     /gene="mscL"
                     /locus_tag="VU534_001811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HEU1514354.1"
                     /translation="MLKNLKSFLLRGNVIDLAVGVVIASAFGAIVTSLVNDIITPLIL
                     NPALKAAKVERIAQLSWHGVGYGNFLSAIINFIFVGTALFFIIKGIEKAQKLTGIKEE
                     KTDEKKPTELEVLQEIKALLEKK"
     gene            complement(5126..6220)
                     /gene="hemH"
                     /locus_tag="VU534_001812"
     CDS             complement(5126..6220)
                     /gene="hemH"
                     /locus_tag="VU534_001812"
                     /EC_number="4.98.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrochelatase"
                     /protein_id="HEU1514355.1"
                     /translation="MKKAILMMTFGSPEEIIFEGVADFFTNIRRGVRPQDHEIQTLYD
                     NYVRIGGTPLQKITRQEVALVEARLGSEYSVYFANKFSSPFIPDVIGQMEADGIEQCI
                     CLILEPHYSFYSVMGYEKFLESKQIQFLVIKDWYQEEALLNYWADEIAKILKEEVKED
                     SFKVIFSAHSVPIFALDFGDPYIDQIFENSKLVAEKLGLSSEQYTNTWQSESDIGIPW
                     IKPDVLEYLREQTEHPDHYIFVPISFISEHIEVLFDNDVECYDLCQEFGVNYHRPPMP
                     NTDSRLIDALVNTVRVNENQEFKEFLPEEETFDELVPSDETKNILAESQDLQMPEFVK
                     KLIEKKGRENVKMPYLIKKMLEKAGKLPKE"
     gene            6375..7598
                     /gene="pepT"
                     /locus_tag="VU534_001813"
     CDS             6375..7598
                     /gene="pepT"
                     /locus_tag="VU534_001813"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000222045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HEU1514356.1"
                     /translation="MTYPNLLDRFLTYVKVNTRSDEHSTTTPSTQSQVDFATNVLIPE
                     MKRVGLQNVYYLPNGFAIGTLPANDPSLTRKIGFISHMDTADFNAEGVNPQVIENYDG
                     GVIELGNSGFKLDPADFKSLEKYPGQTLITTDGTTLLGADDKSGIAEIMTAIEYLTAH
                     PEIKHCEIRVGFGPDEEIGVGANKFDAEDFDVDFAYTVDGGPLGELQYETFSAAGAEL
                     HFQGRNVHPGTAKGQMVNALQLAIDFHNQLPENDRPELTEGYQGFYHLMDVTGSVEEA
                     RASYIIRDFEKDAFEARKASMQSIADKMNEELGSDRVTLNLTDQYYNMKEVIEKDMTP
                     ITIAKAVMEDLGITPIIEPIRGGTDGSKISFMGIPTPNIFAGGENMHGRFEYVSLQTM
                     ERAVDTIIGIVAYKG"
     gene            complement(7634..8263)
                     /locus_tag="VU534_001814"
     CDS             complement(7634..8263)
                     /locus_tag="VU534_001814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000030436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1514357.1"
                     /translation="MSKANQLLEQIHEEGIRQSLAEEVENLKAATNKADADLDEVNSQ
                     VKDVLTRIASALQQEKENAEQDPQTLVLYQKLYDILMSLHSYLESNNGSDADFDKVDA
                     LLDQLSAKSKDKTALLESTKAILVLNHQIQSKASASEETSPARNAEANGDNTSAENQP
                     NATAESNIETASDENKPSNTRDSKPAESTSENETTESSTTTGNQEKPVE"
     gene            8228..8449
                     /locus_tag="VU534_001815"
     CDS             8228..8449
                     /locus_tag="VU534_001815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1514358.1"
                     /translation="MDLFQELICLAQKTFYFFLAICRRLLVAIYHVLLKQESYNPRLQ
                     GLTEIRNPDKTMFVQDAIRFAQQHGFNML"
     gene            complement(8720..9731)
                     /locus_tag="VU534_001816"
                     /pseudo
     CDS             complement(8720..9731)
                     /locus_tag="VU534_001816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669441.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
     gene            complement(9957..13076)
                     /gene="phtE"
                     /locus_tag="VU534_001817"
     CDS             complement(9957..13076)
                     /gene="phtE"
                     /locus_tag="VU534_001817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtE"
                     /protein_id="HEU1514359.1"
                     /translation="MKFSKKYIAAGSAVIVSLSLCAYALNQHRSQENKDNNRVSYVDG
                     SQSSQKSENLTPDQVSQKEGIQAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDALFSE
                     ELLMKDPNYQLKDADIVNEVKGGYIIKVDGKYYVYLKDAAHADNVRTKDEINRQKQEH
                     VKDNEKVNSNVAVARSQGRYTTNDGYVFNPADIIEDTGNAYIVPHGGHYHYIPKSDLS
                     ASELAAAKAHLAGKNMQPSQLSYSSTASDNNTQSVAKGSTSKPANKSENLQSLLKELY
                     DSPSAQRYSESDGLVFDPAKIISRTPNGVAIPHGDHYHFIPYSKLSALEEKIARMVPI
                     SGTGSTVSTNAKPNEVVSSLGSLSSNPSSLTTSKELSSASDGYIFNPKDIVEETATAY
                     IVRHGDHFHYIPKSNQIGQPTLPNNSLATPSPSLPINPGTSHEKHEEDGYGFDANRII
                     AEDESGFVMSHGDHNHYFFKKDLTEEQIKAAQKHLEEVKTSHNGLDSLSSHEQDYPSN
                     AKEMKDLDKKIEEKIAGIMKQYGVKRESIVVNKEKNAIIYPHGDHHHADPIDEHKPVG
                     IGHSHSNYELFKPEEGVAKKEGNKVYTGEELTNVVNLLKNSTFNNQNFTLANGQKRVS
                     FSFPPELEKKLGINMLVKLITPDGKVLEKVSGKVFGEGVGNIANFELDQPYLPGQTFK
                     YTIASKDYPEVSYDGTFTVPTSLAYKMASQTIFYPFHAGDTYLRVNPQFAVPKGTDAL
                     VRVFDEFHGNAYLENNYKVGEIKLPIPKLNQGTTRTAGNKIPVTFMANAYLDNQSTYI
                     VEVPILEKENQTDKPSILPQFKRNKAQENLKLDEKVEEPKTSEKVEKEKLSETGNSTS
                     NSTLEEVPTVDPVQEKVAKFAESYGMKLENVLFNMDGTIELYLPSGEVIKKNMADFTG
                     EAPQGNGENKPSENGKVSTGTVENQPTENKPADSLPEAPNEKPVKPENSTDNGMLNPE
                     GNVGSDPMLDPALEEAPAVDPVQEKLEKFTASYGLGLDSVIFNMDGTIELRLPSGEVI
                     KKNLSDLIA"
     gene            complement(13286..>13703)
                     /locus_tag="VU534_001818"
     CDS             complement(13286..>13703)
                     /locus_tag="VU534_001818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="histidine motif-containing protein"
                     /protein_id="HEU1514360.1"
                     /translation="KNKVDQDSKPDEDKEHDEVSEPTHPESDEKENHAGLNPSADNLY
                     KPSTDTEETEEEAEDTTDEAEIPQVENSVINAKIADAEALLEKVTDPSIRQNAMETLT
                     GLKSSLLLGTKDNNTISAEVDSLLALLKESQPAPIQ"
BASE COUNT         4002 a         2745 c         2376 g         4580 t
ORIGIN      
        1 attgctcaaa agttaattga aaagatttct atgactgata ttgcccatca gctttccatc
       61 tcaacttcaa ctgttattcg taagctcaat gactttcact ttaaacatga tttttcttgt
      121 cttcctgaga ttatgtcttg ggatgagtat gcttttacaa aaggaaagat gagcttcatt
      181 gcgcaagatt ttaacaatct caatatcatc actgttctta agggaagaac acaagctgtc
      241 atccgaaatc actttcttaa atatgataga gccgtccgat gtcgcgtcaa aatcattact
      301 atggatatgt ttagtcctta ctatgactta gctagacaac ttttcccgtg tgctaaaatc
      361 gtgttggatc gctttcacat tgtacaacat cttagccgtg ctatgagtcg tgtgcgtgtc
      421 caaatcatga atcagtttca tcgaaaatcc catgaataca aggctatcaa gcgctactgg
      481 aaactcattc aacaggatag ccgtaaactg agtgataagc gattttatcg tcctactttt
      541 cgtatgcact taaccaataa agagatttta aacaagcttt tgagctattc acaaaacttg
      601 aaacatcact atcagctcta tcaactcttg ctgtttcact ttcagaataa ggaaccggag
      661 aaatttttcg gactcattga ggacaatctg aagcaggttc atcctatttt tcagactgtc
      721 tttaaaacct ttctaaagga caaaaagaaa atcgtcaaca cccttcaact accctattca
      781 aacgccaaat tggaagcgac caataatctc atcaaactta tcaagcgcaa tgcctttggt
      841 tttcggaact ttgaaaactt caaaaaacgg atttttatcg ctctgaatat caaaaaagaa
      901 aggacaaaat ttgtcctttc tcgagcttag ctgacttcaa cccactacag ttgacaaaga
      961 gccggatttt attgtcttta ttagtaatct ggtcttaaga cccctgttac agttgcctta
     1021 gttgcttcgt agtcgccatc tacgacaacc ttgataatgc gtttggcatc ttcttctggt
     1081 gctggaacaa gaggtagacg agtgggtcca gcttcaaatc ccatatagtt aagaattgcc
     1141 ttaactggag caggacttgg ataagagaag agagcattaa ccttaggaat gaatttacgc
     1201 tgaattgctg cggctttctt catatcgctt tctgcaatcg cagtaaacat ctcgtgcatt
     1261 tcatccccat ttgtatgaga ggcaacagaa ataaccccat ccgccccaag gttcatggca
     1321 tggaaagcat ctccatcctc acctgtataa atcaagaact cttcaggctt gtgctcaatc
     1381 aagtaagcca tattagccaa gctagtacat tctttgacac cgataatatt tggatggtca
     1441 gccaagcgaa gcatggtttc tggagtcaat tcgacaacta cacgccctgg aatgttatag
     1501 ataataattg gtaggtcaga agcatctgca atagtcttaa agtgctgata catcccttct
     1561 tgagaaggtt tgttgtagta aggaacaata gcaagcccag ctgcgaaacc accaaattcc
     1621 gctacttctt tgacaaactc aatagagtca cgcgtatcat tagtacctac acccgcaatc
     1681 aaaggaacgc gtccattgac aaccttttgt acagccgcaa acaactccaa ctcctcatcg
     1741 tgggtcaaag ttggactctc agcagtcgtt cctgcgagaa gaattccatc cgtatgatgg
     1801 gccaataaat gctcaatcaa ggctggaata gcatcaaagt taatggaacc atcctcatgg
     1861 aagggggtaa taaaggctgt aatgatttta cattttttta aatcttgata agacacgaaa
     1921 acacctctct atttcaaaga aggagttcat ctgaactcct aaacgatatg actattttaa
     1981 ttcaaatttc aattcggctg ttggacgaac caatccacgt tcatgaagag tttcagcaat
     2041 ctgaactgag ttccaagcag cacctttgag aaggttatct gaaacaaccc acatgtgaat
     2101 tcctttttct gcatccaagt ctttacggat acgaccaaca aaggtatcac gcgaaccaac
     2161 tgcattgata gcttgaggat agatttgatg agctacatca tcttcaagaa cagcacctgg
     2221 gaaggctgcg atagctgctt ttacttcttc gattggagcc acttcttttg tttcgatata
     2281 aacagactca gagtgagctg acaagactgg aatacgcaca catgttgcag atactgcaat
     2341 gctatcatct tccataattt tcttagtttc cttggtcatc ttcatctctt cgtacgtgta
     2401 atcattatca gtgaaaacat caatttgtgg aagagcgtta aaggcgatag gataatgttt
     2461 cttgtcacca cctgaaggca agatttccgc atgcaaatca cgtggtttca caccatcatt
     2521 caagacttca cgaagttcac gttgtgtctc aagaattgct cccataccag cacctgaaac
     2581 ggcttgataa gttgaaacaa tgatacggtc caagccccat ttttggcgaa ccggctcaag
     2641 agccaccatc atttgaattg ttgaacaatt agggcaggca atgattccgt tgtgagcatc
     2701 aagtgcatga gcattgacct ctggaacaac caaaggaaca tctggatttt gacggaaata
     2761 agatgtatta tctactacta ccacgccagc ttttactgcg tatggtgcat acttagctga
     2821 tgtagaacta cctgctgaaa agagagcaat atcaactcct tcaaaagctg tttcagtcgt
     2881 ttcttcaatt gtaatatctt gatctttaaa tttcaatgac ttacctgctg aacgtgcaga
     2941 agcaaggtaa cgaattttat cgattggaag tgttgattct tccaacattt ttatcatctg
     3001 agcaccgaca gcacctgtcg cgccgactac agcaactgta tatcccataa ataacctctt
     3061 tcggaatttt ctaaaaattt ctataataga agtattatac tactttttcc atgaattgca
     3121 aagctttttc atcatttttt ggaaaataaa aatcccagtc gctagactag ggactaagag
     3181 gcatcttcat gtgatgagca ggttcacaca actcatcaag gtccgctcct gcgttatgac
     3241 ctcctcatgc tcaatagtag tccgaagact acctatcgac tcatcgcata ttctatatta
     3301 ctagagatac ttgattttgt caataagaaa tttttcagat cgagtataac aaaaaactct
     3361 cgtattcaag agtttcccta tacatatcat gctaattgcc gggattgaac cggcgacctc
     3421 atccttacca tggatgcgct ctgccaactg agctaaatca gcttacttaa gaagtatact
     3481 atattcagaa aaacttgtca agtttcctta gaaattttcc ataggaaaaa gccaggtaaa
     3541 aactacctag cttatcttct tctatttact taaatcaatt cgacgaccaa ttttaccaat
     3601 aataatcgct ccaataatca atgaagcaaa ttcaccgatt cctgttgtaa accaagtaag
     3661 gaagaatggt aattctgcta caatatttaa ctctgcagcg atagtaaaca tggaaattga
     3721 aaagaggatt gaaaagaaga aatgatcttt tcgaatcaat ccgttaaaga ggtaatcctt
     3781 gctatatttt gcaaaaagcc aaacacctaa actgaggaat actaaggttg aaccaccacc
     3841 aacaaagaca tctagcagtc cgaagctaaa gaaattagca atcatacaac cgatggtaac
     3901 tccgatgatg tacttaggat tgtaaaaagc cataaagttc atcatttctg aaatacgaaa
     3961 ctgataagca ccatagctga tggcatttag gggcggtgtg acagtcaaaa cgacgtagat
     4021 agcagcgacg attgcaatat ctgcaacatc acgaatagtt aattttttca tcttttctcc
     4081 tttggcggtt atccgcgtgt aatatgcttg gtgaaagaag ctaagcacca agggttgatt
     4141 cattcaacct tactagtata gcacaatagc ctgctttatg ctatacttaa agcatgaaaa
     4201 aacctattca aaaatttttt aacaatgaaa tcttagccta tctctttttt ggtatagtga
     4261 ctactcttgt tgctatacta tcacgattag tcatttatca gctaagtcat caggaactcc
     4321 ttgctacggc cttggcaaat attatcggta tcctatttgc ctttatcaca aatgatacga
     4381 ttgtatttaa gcaaaaaaag aaaaatagac ttatccgttt agtgaaattt tctcttgccc
     4441 gcctttctac ttttctgtta gacttgtttt taacttttct ctttgtaacc caatttcctc
     4501 acatcatagg gcaattcgta actgaaaaca ttgataagat aaatgctatt gaaacaataa
     4561 ttgcacaaat attcattatt atcatcaatt atatcttgag caaggtctat atttttagaa
     4621 aataatgctc catttatgag ccttttaatt gccttctata atgatttagg atacaatgaa
     4681 acacgaaaca ttgaaaggaa aacagtatgt taaaaaatct aaaatcgttc ttgcttcgag
     4741 gaaatgttat tgaccttgct gtcggtgttg taattgcctc tgcttttggt gctatcgtta
     4801 cttcacttgt aaacgacatt atcactcctc ttattttaaa tcccgctttg aaagctgcta
     4861 aagttgaacg tatcgctcaa ctttcttggc atggagtcgg ctatggtaac ttcttaagtg
     4921 ctattatcaa ttttatcttt gtgggtaccg ccctcttctt tattatcaag ggcattgaaa
     4981 aagcacagaa gctgactggc ataaaggaag aaaaaactga cgaaaaaaaa ccaaccgaat
     5041 tggaagtcct tcaagaaata aaagctctcc ttgagaaaaa ataatcgatt aaaaggatct
     5101 agcgcaaagc taaatccttt tttctttact ctttgggtaa cttgcctgct ttttcaagca
     5161 tttttttgat aagataaggc atcttaacat tttcacgacc ttttttctca atcaattttt
     5221 tcacaaattc tggcatttgt aaatcttgag attcagccaa aatgtttttc gtctcgtctg
     5281 aaggaactaa ctcatcaaag gtctcttctt ctgggagaaa ttccttaaac tcttgatttt
     5341 cattgactct aactgtattg accaaagcat caatcaaacg agaatctgta tttggcattg
     5401 gtggacgatg gtagtttacc ccaaattcct gacataagtc ataacattcc acatcattgt
     5461 caaacaagac ctcaatatgc tcactgatga aactaatagg tacaaaaata taatggtctg
     5521 gatgttctgt ctgttctctg agatactcca aaacatctgg tttaatccat ggaataccaa
     5581 tatcactctc actttgccaa gtgttggtat attgttctga actcaagccc agtttttcag
     5641 cgactagctt gctattttcg aaaatttggt ctatataagg atcaccaaag tccaaggcaa
     5701 aaataggcac actatgggct gaaaagatga ctttaaagct gtcttccttt acttcttctt
     5761 ttaaaatctt agcaatttca tctgcccaat agtttaagag cgcttcttcc tgataccagt
     5821 ccttaatgac caaaaattga atttgtttgc tttctaaaaa tttttcatag cccatgacag
     5881 agtagaaaga ataatggggc tccaaaatca agcaaataca ctgttcaatt ccgtctgctt
     5941 ccatttgacc gatcacatct ggaataaagg gactggaaaa cttattagca aagtagacac
     6001 tgtattcact ccccagccta gcttctacca aggcaacctc ttgacgggta attttttgca
     6061 gaggcgtgcc tccaattcgt acataattat cataaagagt ctgaatctcg tggtcttggg
     6121 gtctcacccc acgacgaata tttgtgaaaa aatcagctac accttcaaag ataatctctt
     6181 ctggtgaacc gaaggtcatc attaaaattg cttttttcat gactgcttcc ttgtgatgtt
     6241 tttatcaagt ttattttatc attaattcat cgataagtaa acgctagcat agggacattc
     6301 tcaatcttct gtcttttgtt tttctcttct ttctatgata caatggaaaa aataaattca
     6361 aaaggagttt ttttatgact tatccaaatc tcttggaccg cttcttaacc tatgttaagg
     6421 tcaacacgcg ctctgatgaa cactctacta ctactccaag tacacagagt caggttgact
     6481 tcgcaacaaa tgtcctaatt cctgaaatga aacgtgttgg actgcaaaat gtttactatc
     6541 taccgaatgg ttttgctatt ggaaccttgc cagccaacga tccgtcttta acacgtaaga
     6601 ttggttttat atcgcacatg gatactgctg attttaatgc tgaaggagtc aatccacagg
     6661 taattgaaaa ctacgatggt ggtgtgattg aactagggaa ttctggtttc aaactcgatc
     6721 cagctgactt caagagtctt gaaaaatatc caggacaaac gctcatcaca acagatggaa
     6781 caaccttgct aggtgctgat gacaagtcag gaattgctga aattatgaca gccattgaat
     6841 atctaactgc tcatcctgaa attaagcact gtgagattcg tgttggtttt ggtccagatg
     6901 aagaaatcgg tgttggtgcc aataaatttg atgcagaaga ttttgatgtg gattttgcct
     6961 acactgttga tggtggtcca ctaggtgaac ttcagtacga gactttctca gccgctggtg
     7021 ctgaattgca tttccaaggt cgtaatgtcc accctggtac tgccaaaggg cagatggtca
     7081 atgcccttca gctagcaatt gattttcata atcaacttcc agaaaatgac cgacctgagt
     7141 taactgaagg ttaccaaggt ttttaccatc taatggatgt gacaggtagt gttgaggagg
     7201 cgcgtgcaag ctacatcatt cgtgattttg aaaaagatgc ctttgaagcg cgtaaagcat
     7261 ccatgcaatc tatcgctgat aagatgaatg aagaacttgg gagcgaccgt gtcactctca
     7321 acttgacaga ccagtactac aatatgaaag aagtcattga aaaagatatg actccaatta
     7381 ccattgctaa agccgttatg gaagatctag gtatcacgcc tattatcgaa ccaatccggg
     7441 gtggaacaga cggctctaag atttccttta tgggaatccc aactccgaat atctttgcag
     7501 gtggcgaaaa tatgcacgga cgttttgaat acgttagcct tcagactatg gaacgtgcag
     7561 ttgataccat cattggcatc gtagcttata aaggctaaaa agacgaggta gctcagctac
     7621 ttcgcctttc tttttattct actggttttt cttgatttcc agtagttgta gaagattctg
     7681 ttgtttcatt ttctgaagtt gattcagcag gtttagaatc tcttgtattg cttggtttgt
     7741 tttcgtcgct agcagtttca atgttagatt ctgcagttgc gtttggttgg ttctcagcac
     7801 tggtgttatc accatttgct tcagcatttc ttgctggact tgtttcttca cttgcgctag
     7861 cttttgactg gatttgatga ttcaaaacta gaatagcttt tgtcgattca agtaaagctg
     7921 ttttgtcttt actcttagca gaaagttgat ctaataatgc atccacctta tcaaagtccg
     7981 catcagatcc attattactt tctaaataag agtgaagcga catgagaata tcgtagagtt
     8041 tttgatagag tacaagtgtc tgaggatctt gctcagcatt ttccttttct tgttgaaggg
     8101 cgctagcgat acgagtcaag acatctttta cctgactgtt tacttcatcc aagtctgcat
     8161 cagccttgtt tgtggcagct tttagatttt ctacttcttc tgccaaggat tgtctgattc
     8221 cttcttcatg gatttgttcc aagagttgat ttgccttgct caaaagactt tctacttctt
     8281 ccttgctatc tgtcgcagat tattggttgc tatctaccat gtactcctaa aacaggagag
     8341 ttataatcca agattacaag gccttacaga aataagaaat ccagataaga caatgttcgt
     8401 ccaagacgct attcgcttcg cacagcagca cggattcaat atgctttaat tttaaagttt
     8461 aggtgtcaag acctcttttt agtgtgccca aaatttagag aagtaatcaa tcaactaact
     8521 tttatttttt tcaaactttc agtaaactga cctaaagcta actcaatctg tctttgtaga
     8581 tgcttctgct atcagctaga agttgatcta cttttgccaa gactgccttc tcatcaaaag
     8641 ttccaggttg atagttggat tgcagggatg gaatcttgtt tttcaaagcc gcttcatatc
     8701 ccttagtttg aaccttgatg tagtgattgt ggtcgccatg aggaatcaca aaaccttctg
     8761 aatcttcact tataattcga ttggcatcaa aaccatgacc atcttcttcc tcatgatgga
     8821 catgtagtga cggattactt aatacagaac tagaagaact tcctacctct tccgtgttag
     8881 agtgtgatgg gggattgtta agagatgact taggaatata gtgatagtga tccccatgtc
     8941 ttactatata agcatcacct gtatctctga caatatcatt agggttaaag acatatgtgg
     9001 ctgctaattc acctgccgac aagtcactct caggaatgaa atgatagtga ccaccatgtg
     9061 gtactatagt agattgaaat agaatatgag caaattgata aggggatttt aaagtaattt
     9121 ctaacaatga tttagaaact atgatgtgct attctaaatt caactcacta tatataacca
     9181 tcatcggtag tataacgtcc ctgtaatttt gctacagata cttctgcact agctccttta
     9241 tcgtctttac catgttcttg tttttggcga ttgatttcat cttttgttcg tacattttct
     9301 gcatgagctt gatctttaag gtaaacataa tactttccat ctaccttaat aatatatcct
     9361 cccttaacct aactgacgat atcttgatct ttcggctgat agttgggggc tttcattaat
     9421 agctcttcac taaagagcgc atcaaaagga actttaccat tatagtagtg ataatgatcg
     9481 ccatgagaag ttacataacc ttgatctgta atcttaataa caatttgttt tgcttgaatt
     9541 ccttcttttt gactaaccta gtctggagtc aaattttcag tcttcttagt gtctttatta
     9601 ctgtttacat atgaaacacg atttttatct gtattggcct gttagctatg ttggttcaga
     9661 gcataaacac acagacttaa ggaaaggata acaacagatc cagctgctat atatttcttt
     9721 ttaaatttca taattacctc atttctataa ttatttatat gatgtcttca ttattaaatg
     9781 attaaataaa ttaattaacc aattaattaa ctagtaaata ttccacctct ttttaagttg
     9841 tatgtcaaga aattttatat attaataata aaatgaaatt ctcccaaagt cagagtttta
     9901 tttctaactt ttgagagaac ttcatttttg attcagactt tttctactgc tattccttac
     9961 gctatgagat cagataaatt cttttttatc acttctccac ttggcaatct taattcaatc
    10021 gttccatcca tattgaatat aacactatct aagcctaatc cgtaactagc tgtaaatttt
    10081 tctaattttt cttgtacagg atctactgct ggagcttcct ctaatgctgg atctaacata
    10141 gggtcactcc ccacattccc ttctggattc aacattccat tatccgttga gttttctggt
    10201 tttacaggtt tttcgtttgg tgcctctggt aaagaatctg ctggtttatt ttctgttggt
    10261 tggttctcaa ctgttccagt agatactttt ccattttcag atggtttatt ttcaccattt
    10321 ccttgaggtg cttctcctgt aaaatctgcc atattctttt taatgacttc tcccgatggt
    10381 aaatataatt caattgttcc gtccatatta aacaagacat tttctagctt catcccataa
    10441 ctttcagcaa attttgctac tttttcttgt acaggatcca ctgtaggaac ttcttctaac
    10501 gttgaattac tagtactatt cccagtttca gaaagttttt ctttttctac cttctcacta
    10561 gtctttggtt cttctacctt ttcatcaagt tttaagtttt cttgtgcttt attcctttta
    10621 aattgtggta gaatacttgg tttatcagtt tgattttctt tttccaagat aggtacttcc
    10681 acaatataag tcgattgatt gtccaaataa gcatttgcca tgaaggttac aggaatttta
    10741 tttccggccg ttctggttgt tccttggttt aatttcggaa tcggtaattt gatttcacca
    10801 actttatagt tattttctaa ataagcattt ccatgaaatt catcaaacac tctgactaaa
    10861 gcatcagttc ctttaggcac tgcaaattga gggttcactc ttaaataagt atcccctgca
    10921 tggaaaggat agaaaatcgt ttgactggcc attttgtaag ctaaagaggt tggaactgta
    10981 aatgtaccat cataacttac ttctggataa tcttttgaag cgatagtata cttaaatgtt
    11041 tgtcctggta aataaggttg atctaattca aagtttgcaa tattccctac tccttctcca
    11101 aatactttac cagatacttt ctccaatact tttccatctg gtgttattaa ttttactagc
    11161 atattgatac ctaatttttt ctccaattca ggcggaaaac taaaagaaac gcgtttttga
    11221 ccattggcta gagtaaagtt ttgattatta aacgtactat tttttaacaa attaacaaca
    11281 ttcgttaatt cttctccagt ataaacttta ttcccttctt ttttagcaac tccttcttcg
    11341 ggtttaaaca gttcatagtt actgtgagaa tgaccaattc caaccggttt atgttcatca
    11401 atcggatctg catgatggtg atctccatgc ggataaataa tcgcattttt ttctttattc
    11461 acgacaatac tttcacgttt gacaccatat tgtttcataa tgccagcaat tttttcttcg
    11521 atttttttat ctaaatcttt catttctttg gcattacttg gataatcctg ttcatgagat
    11581 gacaaagaat ctaatccatt atgactagtt ttaacttcct ctaaatgttt ttgcgcagcc
    11641 ttaatttgct cttctgtcaa gtccttcttg aagaaataat gattgtggtc tccgtgactc
    11701 atgacaaaac ctgattcatc ttcagcgata atacgattag catcaaatcc gtatccatct
    11761 tcttcatgtt tctcatgtga agttcctgga ttgattggaa gagatggaga aggtgttgct
    11821 agactattgt ttggaagagt cggttgccca atttgatttg attttggaat gtaatggaaa
    11881 tgatcaccat gtcttacaat ataagctgta gccgtttctt caacgatatc ttttggatta
    11941 aaaatataac catcagatgc tgaagagagc tccttacttg tcgttaaaga agaaggattg
    12001 cttgaaagac tgcctagact agacactact tcattaggtt ttgcatttgt agaaactgta
    12061 gaaccagttc cactgatagg caccattctg gcaatctttt cttctaaggc agaaagcttg
    12121 ctgtaaggaa taaagtggta atggtcgcca tgcggaatcg caactccatt tggtgtacga
    12181 ctgataatct tagcagggtc aaagaccagg ccatctgatt cactgtaacg ttgggcgcta
    12241 ggtgaatcat agagttcctt caaaagactc tggagatttt cagatttatt tgctggcttg
    12301 ctagttgatc cttttgctac agattgcgtg ttattgtcac tagctgttga agaatagctt
    12361 aactgactcg gttgcatatt ttttccagcc agatgtgctt tagctgctgc taattcacta
    12421 gcagataaat cgcttttggg aatgtagtga tagtgacctc catgaggaac gatataagca
    12481 ttacccgtat cttcgataat atcagctgga ttaaagacat aaccatcatt tgtcgtatat
    12541 cgtccctgag accttgctac agcaacatta gagttaacct tctcattatc tttgacatgt
    12601 tcttgttttt gacgattgat ttcatcttta gttcgaacat tatcagcatg agctgcatct
    12661 ttcaggtaga cataatattt tccatcgacc ttgatgatat aaccaccctt gacttcattg
    12721 acaatatcag cgtctttaag ttgatagttt ggatccttca tcaagagttc ttcactaaag
    12781 agggcatcat aaggaacttt cccattatag taatgatagt ggtcaccgtg tgacgttaca
    12841 tagccctgat ctgtaatttt gattacaatt tgctcagcct gaattccttc tttctggcta
    12901 acctggtctg gtgtcaagtt ttcacttttc tgacttgact ggctgccatc cacataagag
    12961 acacgattat tgtccttatt ttcctgcgaa cgatgctggt ttagtgcata ggcacataga
    13021 ctcaaggata cgataacagc tgatccagct gctatatatt ttttactaaa tttcataaat
    13081 ccctcatttc aataaatgat gaagtttttt ctcaacttct tttactttat taaatagttt
    13141 tctaaaccgg ttatttaacc atttaattaa ccagtaaata gtttactatt taaaattact
    13201 tttgtcaagt ttctgttagg tttttctaaa aaagagaagt aacatgaaag gttacttctc
    13261 cataaaatat gctccattca ttttactact gtataggagc cggttgactt tcttttaaca
    13321 aagccaagag actatctact tctgctgaaa tagtgttatt atctttcgtt ccgagaagaa
    13381 gactactttt tagaccagtc aatgtctcca tagcattttg tctaatacta ggatctgtta
    13441 ctttttctag caaggcctcc gcatctgcta tcttagcgtt aataacagaa ttctctactt
    13501 gaggaatttc agcctcatct gtggtatctt cagcttcttc ctctgtctct tccgtatcag
    13561 tgcttggttt ataaagatta tctgctgaag gatttaaacc agcgtgattc tctttttcat
    13621 cagattcagg gtgagttggc tcacttactt catcatgttc cttatcttca tcaggtttac
    13681 tgtcttggtc taccttattt tta
//
LOCUS       DAVFER010000054        13428 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1105170250
            SAMEA2167659-rid19724873.denovo.054, whole genome shotgun sequence.
ACCESSION   DAVFER010000054 DAVFER010000000
VERSION     DAVFER010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2167659
            Sequence Read Archive: ERR388902
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13428)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13428)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928716.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928716.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 04:07:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,118
            CDSs (total)                      :: 2,073
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 120
            CDSs (without protein)            :: 120
            Pseudo Genes (ambiguous residues) :: 0 of 120
            Pseudo Genes (frameshifted)       :: 67 of 120
            Pseudo Genes (incomplete)         :: 47 of 120
            Pseudo Genes (internal stop)      :: 34 of 120
            Pseudo Genes (multiple problems)  :: 23 of 120
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13428
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2167659-rid19724873.denovo.054"
                     /strain="1105170250"
                     /db_xref="taxon:1313"
     gene            complement(<1..800)
                     /gene="lytB"
                     /locus_tag="VU534_001819"
     CDS             complement(<1..800)
                     /gene="lytB"
                     /locus_tag="VU534_001819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endo-beta-N-acetylglucosaminidase"
                     /protein_id="HEU1514361.1"
                     /translation="MNLGEFWYNKINKNRGRRLMKKVRFIFLALLFFLASPEGAMASD
                     GTWQGKQYLKEDGSQAANEWVFDTHYQSWFYIKADANYAENEWLKQGDDYFYLKSGGY
                     MAKSEWVEDKGAFYYLDQDGKMKRNAWVGTSYVGATGAKVIEDWVYDSQYDAWFYIKA
                     DGQHAEKEWLQIKGKDYYFKSGGYLLTSQWINQAYVNASGAKVQQGWLFDKQYQSWFY
                     IKENGNYADKEWIFENGHYYYLKSGGYMAANEWIWDKESWFYLKFDGK"
     gene            complement(842..1780)
                     /locus_tag="VU534_001820"
     CDS             complement(842..1780)
                     /locus_tag="VU534_001820"
                     /EC_number="1.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000210709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HEU1514362.1"
                     /translation="MTTNRLQVSLPGLDLKNPIIPASGCFGFGQEYAKYYDLDLLGSI
                     MIKATTLEPRFGNPTPRVAETPAGMLNAIGLQNPGLEVVLAEKLPWLEREYPNLPIIA
                     NVAGFSKQEYAAVSHGISKATNVKAIELNISCPNVDHCNHGLLIGQDPDLAYDVVKAA
                     VEASEVPVYVKLTPSVTDIVTVAKAAEDAGASGLTMINTLVGMRFDLKTRKPILANGT
                     GGMSGPAVFPVALKLIRQVAQTTDLPIIGMGGVDSAEAALEMYLAGASAIGVGTANFT
                     NPYACPDIIENLPKVMDKYGISSLEELRQEVKESLR"
     gene            complement(1791..2591)
                     /locus_tag="VU534_001821"
     CDS             complement(1791..2591)
                     /locus_tag="VU534_001821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="HEU1514363.1"
                     /translation="MNPTCKKRLGVIRLETMKVVAQEEIAPAIFELVLEGEMVEAMRA
                     GQFLHLRVPDDAHLLRRPISISSIDKANKQCHLIYRIDGAGTAIFSTLSQGDTLDVMG
                     PQGNGFDLSDLDEQNQVLLVGGGIGVPPLLEVAKELHERGVKVVTVLGFANKDAVILK
                     TELAQYGQVFVTTDDGSYGIKGNVSVVINDLDSQFDAVYSCGAPGMMKYINQTFDDHP
                     RAYLSLESRMACGMGACYACVLKVPENETVSQRVCEDGPVFRTGTVVL"
     gene            complement(2841..3221)
                     /locus_tag="VU534_001822"
     CDS             complement(2841..3221)
                     /locus_tag="VU534_001822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEU1514364.1"
                     /translation="MASKMLHTCLRVENLEKSIAFYQDAFGFKELRRRDFPDHAFTIV
                     YLGLEGDDYELELTYNYDHGPYVVGDGFAHIALSTPDLEALHQEHSAKGYEVTEPNGL
                     PGTTPNYYFVKDPDGYKVEVIREK"
     gene            complement(3279..3638)
                     /gene="rplT"
                     /locus_tag="VU534_001823"
     CDS             complement(3279..3638)
                     /gene="rplT"
                     /locus_tag="VU534_001823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019786714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HEU1514365.1"
                     /translation="MARVKGGVVSRKRRKRILKLAKGYYGAKHILFRTAKEQVMNSYY
                     YAYRDRRQKKRDFRKLWITRINAAARMNGLSYSQLMHGLKLAEIEVNRKMLADLAVND
                     AVAFTALADAAKAKLGK"
     gene            complement(3690..3890)
                     /gene="rpmI"
                     /locus_tag="VU534_001824"
     CDS             complement(3690..3890)
                     /gene="rpmI"
                     /locus_tag="VU534_001824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001125942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HEU1514366.1"
                     /translation="MPKQKTHRASAKRFKRTGSGGLKRFRAYTSHRFHGKTKKQRRHL
                     RKASMVHSGDYKRIKAMLTRLK"
     gene            complement(3923..4453)
                     /gene="infC"
                     /locus_tag="VU534_001825"
     CDS             complement(3923..4453)
                     /gene="infC"
                     /locus_tag="VU534_001825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000848185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HEU1514367.1"
                     /translation="MKTIAKQDLFINDEIRVREVRLIGLEGEQLGIKPLSEAQALADN
                     ANVDLVLIQPQAKPPVAKIMDYGKFKFEYQKKQKEQRKKQSVVTVKEVRLSPTIDKGD
                     FDTKLRNARKFLEKGNKVKVSIRFKGRMITHKEIGAKVLAEFAEATQDIAIIEQRAKM
                     DGRQMFMQLAPATDKK"
     misc_feature    complement(4469..4600)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00558"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L20 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00558"
     gene            complement(4764..5948)
                     /locus_tag="VU534_001826"
     CDS             complement(4764..5948)
                     /locus_tag="VU534_001826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU1514368.1"
                     /translation="MKDVSLFLLKKVFKSRLNWIVLALFVSVLGVTFYLNSQTANSHS
                     LESRLESRIAANERAINENEEKLSQMSDTSSEEYQFAKNNLDVQKNLLTRKTEILTLL
                     KEGRWKEAYYLQWQDEEKNYEFVSNDPTASPGLKMGVDRERKIYQALYPLNIKAHTLE
                     FPTHGIDQIVWILEVIIPSLFVVAIIFMLTQLFAERYQNHLDTAHLYPVSKVTFAISS
                     LGVGVGYVTVLFIGICGFSFLVGSLISGFGQLDYPYPIYSLVNQEVTIGKIQDVLFPG
                     LLLAFLAFIVIVEVVYLIAYFFKQKMPVLFLSLIGIVGLLFGIQTIQPLQRIAHLIPF
                     TYLRSVEILSGRLPKQIDNVDLNWSMGMVLLPCLIIFLLLGILFIERWGSSQKKEFFN
                     RF"
     gene            complement(5952..6539)
                     /locus_tag="VU534_001827"
     CDS             complement(5952..6539)
                     /locus_tag="VU534_001827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000939891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU1514369.1"
                     /translation="MLQLTHVTLKTRQVILQDVDFTFKKGRVYGLLAINGSGKTTLFR
                     AISNLIPISSGNIAAPPSLFYYESIEWLDGNLSGMDYLRLIKNIWKSGLNLRDEIAYW
                     EMSDYISLPIRKYSLGMKQRLVIAMYFLSQAKCWLMDEITNGLDEYYRQKFFDRLAQI
                     DRQEQLVLLSSHYKEELVDVCDRVVTIHQGQIEEV"
     gene            complement(6572..6760)
                     /locus_tag="VU534_001828"
     CDS             complement(6572..6760)
                     /locus_tag="VU534_001828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1514370.1"
                     /translation="MTVTKSYKYDWNTVWEYSTNYHDHQYAWIPSWSRYDSYSEYKVG
                     GGWNYARYEVINYYSGGY"
     gene            complement(6939..9179)
                     /locus_tag="VU534_001829"
     CDS             complement(6939..9179)
                     /locus_tag="VU534_001829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
                     /protein_id="HEU1514371.1"
                     /translation="MLQWIKNFSIPLIYLSFLLLWLYYAIFSASYLALLGFVFLLVCL
                     FIQFPWKSAGKVLIICGIFGFWFVFQNWQQSQASQNLADSVERVRILPDTIKVNGDSL
                     SFRGKSNGRAFQVYYKLQSEEEKEAFQALTDLHEIGLEGKLSEPEGQRNFGGFNYQAY
                     LKTQGIYQTLNIKTIQSLQKIGSWDIGENLSSLRRKAVVWIKTHFPDPMGNYMTGLLL
                     GHLDTDFEEMNELYSSLGIIHLFALSGMQVGFFMNGFKKLLLRLGLTQEKLKWLTYPF
                     SLIYAGLTGFSASVIRSLLQKLLAQHGVKGLDNFALTVLVLFIVMPNFFLTAGGVLSC
                     AYAFILTMTSKEGEGLKAVTSESLVISLGILPILSFYFAEFQPWSILLTFVFSFLFDL
                     VFLPLLSILFVLSFLYPVIQLNFIFEWLEGIIRLVSQVARRPLVFGQPNAWLLILLLI
                     SLALVYDLRKNIKGLTVLSLLITGLFFLTKYPLENEITMLDVGQGESIFLRDVTGKTI
                     LIDVGGKAESYKKIKKWQEKMTTSNAQRTLIPYLKSRGVAKIDQLILTNTDKEHVGDL
                     SEMTKAFHVGEILVSKDSLKQKEFVAELQATQTKVRSMIVGENLPIFGSQLEVLSPRK
                     MGDGGHDDTLVLYGKFLDKQFLFTGNLEEKGEKDLLKHYPDLKVNVLKASQHGNKKSS
                     SPAFLEKLKPELTLISVGKSNRMKLPHQETLTRLEGINSKVYRTDQQGAIRFKGLDSW
                     KIESVR"
     gene            complement(9163..9813)
                     /locus_tag="VU534_001830"
     CDS             complement(9163..9813)
                     /locus_tag="VU534_001830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000387331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComEA family DNA-binding protein"
                     /protein_id="HEU1514372.1"
                     /translation="MEAIIEKIKEYKIIVICTGLGLLVGGFFLLKPAPQTPVKETNLQ
                     AEVAAVSKDSSTEKEVKKEEKEEPLEQDLITVDVKGAVKSPGIYDLPVGSRVNDAVQK
                     AGGLTEQADSKSLNLAQKVSDEALVYVPTKGEEAVSQQTGSGTASSTSKEKKVNLNKA
                     SLEELKQVKGLGGKRAQDIIDHREANGKFKSVDELKKVSGIGGKTIEKLKDYVTVD"
     gene            complement(9881..10450)
                     /locus_tag="VU534_001831"
     CDS             complement(9881..10450)
                     /locus_tag="VU534_001831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU1514373.1"
                     /translation="MESIFVKFAQYPSIETERLLLRPVTLDDAEAMFDYASDKGNTRY
                     TFPTNQSLEETKNNIAQFYLANPLGRWGIELKSNGQFIGTIDLHKIDSVLKKAAIGYI
                     INKKYWNQGLTTEANRAVIELAFEKIGMNKLTALHDKANPASGKVMEKSGMRFSHAEP
                     YACMDQHEKGRIVTRVHYVLTKEDYFANK"
     gene            10627..11726
                     /gene="ald"
                     /locus_tag="VU534_001832"
                     /pseudo
     CDS             10627..11726
                     /gene="ald"
                     /locus_tag="VU534_001832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003072563.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alanine dehydrogenase"
     gene            complement(12093..12353)
                     /locus_tag="VU534_001833"
                     /pseudo
     CDS             complement(12093..12353)
                     /locus_tag="VU534_001833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003069408.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TfoX/Sxy family protein"
     gene            complement(12356..12856)
                     /locus_tag="VU534_001834"
     CDS             complement(12356..12856)
                     /locus_tag="VU534_001834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000566985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU1514374.1"
                     /translation="MIDQLSKYYSCRILTEKDIPSILSLYESNPLYFQHCPPEPNFAT
                     VKEDMLCLPEGKAKADKFFVGFWNGSDLVAVMDFVYAYPDEETVFIGLFMVDQAYQRK
                     GIGSHIVTEALAYFAKNFRKARLAYVKGNPQSQHFWEKQGFKSIGCEVKQELYTVVIA
                     EQSLED"
     gene            12892..13074
                     /locus_tag="VU534_001835"
     CDS             12892..13074
                     /locus_tag="VU534_001835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1514375.1"
                     /translation="MTQEDALIVISHIKVLSIVPNRCLRPLDKTFSLYNWIFLSQKYI
                     RLVRNLVHFIIDDGTN"
     gene            complement(13039..>13428)
                     /locus_tag="VU534_001836"
     CDS             complement(13039..>13428)
                     /locus_tag="VU534_001836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS5-like element IS1515 family transposase"
                     /protein_id="HEU1514376.1"
                     /translation="KTQIMLDLTTHKVCQMAFSDGHTHDFTLFKESIGQSLPETTLAF
                     VDLGYLGILKFHENTFIPAKNSKNRRLSEDDKQLNKEMSAIRIEIEHFNAKFKTFQIM
                     SVPYRNRRKRFELRAELICAIINYEVN"
BASE COUNT         3915 a         2979 c         2432 g         4102 t
ORIGIN      
        1 attttcccat caaatttgag ataaaaccaa gattccttat cccaaatcca ttcattggct
       61 gccatgtagc caccggattt tagataataa tagtgaccat tctcgaaaat ccattcttta
      121 tcagcatagt ttccattttc tttgatgtaa aaccaagatt ggtattgttt gtcaaaaagc
      181 caaccttgct gtactttggc accactagca ttcacataag cttgattaat ccactgactt
      241 gtcagtagat aaccaccgga tttgaaataa tagtccttcc ctttaatttg gagccattct
      301 ttctctgcgt gctgtccatc tgctttgata taaaaccaag catcgtattg agaatcatag
      361 acccagtctt ctattacttt ggcacctgtt gcaccaacat aggaagttcc tacccaagca
      421 tttcttttca tctttccatc ttggtcaaga taataaaagg ctcccttgtc ttctacccat
      481 tctgatttgg ccatatagcc accagatttg aggtaaaaat agtcgtcacc ttgctttagc
      541 cattcatttt cagcatagtt agcatctgct tttatataga accaagattg ataatgagta
      601 tcaaaaaccc actcatttgc tgcttgactg ccatcttctt tcagatactg ttttccttgc
      661 caagtaccat cactagccat tgcaccctct ggactagcta agaaaaatag cagagctaaa
      721 aaaataaatc ttactttctt cattaacctt cttcctctgt tcttatttat tttattgtac
      781 caaaattctc ctaaattcat attacaaact aataaaaaat caagaacaga ttgattgcag
      841 tttacctcag agactctttt acttcctgac ggagttcttc cagactgcta ataccgtatt
      901 tatccatgac ttttggtaaa ttttcgatga tgtcagggca ggcataagga ttggtaaagt
      961 tagctgttcc aactccgata gcagatgccc cagccagata catttctagg gcagcttcag
     1021 ccgaatccac tcctcccatt ccaatgatag gcaggtctgt tgtttgggca acttggcgga
     1081 tgagtttgag ggctactgga aagactgctg gaccagacat tccacctgtt ccattggcca
     1141 agattggttt tctagttttg aggtcaaagc gcattccaac cagagtattg atcatggtca
     1201 agccacttgc tcccgcatct tctgcagctt ttgcgacagt aacgatatcg gtcacactcg
     1261 gggttaattt gacataaact ggcacttctg aggcttccac agctgctttc accacatcat
     1321 aagccaaatc tggatcttga ccaatcaaaa gtccatgatt acagtggtca acattgggac
     1381 aagaaatatt gagctcgata gcttttacat tagttgcctt ggaaatccca tgagaaacag
     1441 ctgcatactc ttgttttgaa aaaccagcta cattggcaat aataggaaga tttggatatt
     1501 ctctttccag ccaaggtagc ttttcagcca aaacaacctc taaaccagga ttttgcaagc
     1561 caattgcatt gagcatacca gcaggcgtct ctgccactct tggagttgga ttcccaaaac
     1621 gtggttcaag ggttgtcgcc ttgatcataa tagaacctaa aaggtctaaa tcatagtact
     1681 tggcatactc ttgtccaaag ccaaaacagc ctgatgctgg aataatcgga tttttcaaat
     1741 ccaaaccagg tagagaaact tgtaatcgat ttgtagtcat aattttctcc ttataataca
     1801 actgttcctg tgcggaaaac aggaccatct tcacagacgc gttggctgac cgtctcgttt
     1861 tctggtactt ttagaacaca ggcatagcaa gctcccatcc cacaagccat acgagattcc
     1921 agagataaat aggctcttgg gtgatcatca aaggtttgat tgatatactt catcattcct
     1981 ggagccccac acgagtaaac agcatcaaac tgactgtcta aatcattgat aacaacggaa
     2041 acatttccct tgatgccata agaaccatca tctgtcgtta caaagacctg accatactga
     2101 gccaattccg ttttcaaaat aacagcatcc ttattagcaa aaccgaggac tgtcactact
     2161 ttcactccac gttcatgcaa ttccttggcc acctcaagca agggtggaac accaatccca
     2221 ccaccaacaa ggagaacctg attctgctca tcaaggtcag acaagtcaaa accatttccc
     2281 tgaggcccca tcacatcaag agtgtctccc tgacttaagg ttgaaaaaat tgcagtccca
     2341 gctccgtcaa tccgataaat gaggtgacac tgcttgtttg ccttgtcaat agacgaaatt
     2401 gaaataggac gacgtaagag atgggcatcg tccggtacac gcagatgaag aaattggcct
     2461 gctcgcatgg cttcaaccat ttctccttct aggactaatt caaagattgc tggcgcgatt
     2521 tcctcttgtg caaccacctt catggtttcc aaccgaatga cacccaaacg cttcttacat
     2581 gtgggattca taacttttcc tccttaaatt ttaaggggac cagataaaga aaagaccttg
     2641 ctagtgcaag gcctcagtta aaatcgtaca acacaagaga gcacactcaa aaagtctcct
     2701 ctagaaaatt gcaccattct tttatctgac accttgtgag tctctctgga ctccccttaa
     2761 aggttgaatt tttattagta tactctttca gctaaaaaaa gtcaagtaga aaacgaatat
     2821 tctacttaac ttgcacgaaa ttatttttca cgaatgactt cgaccttata tccatcaggg
     2881 tctttgacaa agtaatagtt tggtgtagtt cctggtagac catttggctc agtcacttca
     2941 tagccttttg cactgtgttc ttgatgaagt gcctcaagat caggtgtact gagggcgata
     3001 tgggcaaacc catcaccaac cacatacgga ccgtgatcgt agttataagt caactccaac
     3061 tcatagtcat cgccctcaag acctagatag acaatcgtga aggcatggtc tggaaaatct
     3121 ctgcgacgca attctttaaa accaaaagca tcttgataaa atgcgattga tttttcaaga
     3181 ttttctactc gtaagcaagt gtgtagcatt tttgaagcca tatctttctc ctttatttta
     3241 aaaaagactg gacaatcctg ttccagtctc atcagttgtt atttaccaag ttttgcttta
     3301 gctgcatctg caagagctgt gaaagctact gcatcgttaa cagccaagtc agcaagcatt
     3361 ttacggttaa cttcgatctc agccaatttc aaaccatgca tcaattgtga gtatgaaagt
     3421 ccgttcatac gagctgccgc attgatacga gtaatccaca atttgcggaa gtcacgtttt
     3481 ttctgacgac ggtcacggta tgcatagtag taagagttca ttacttgttc ttttgcagta
     3541 cggaacaaga tgtgtttagc tccatagtaa ccttttgcta atttaagaat acgtttacga
     3601 cgtttgcgtg atacaacgcc acctttaaca cgtgccatgt tttatttcct ccaaatattt
     3661 cctagaattg tttacttaca gtcaagctat tatttcaagc gagtaagcat tgctttgata
     3721 cgtttgtaat ctcctgaatg caccatagat gctttacgaa gatgacgacg ttgtttctta
     3781 gtttttccgt ggaaacggtg agaagtgtaa gcacggaaac gtttaagtcc accagaacct
     3841 gtacgtttga aacgtttagc tgatgcgcgg tgtgtttttt gttttggcat gattttttct
     3901 cctttattta actttctgac aattattttt tgtcagtcgc tggcgccaat tgcatgaaca
     3961 tttgacgtcc atccatttta gcacgttgtt cgatgatggc aatatcttga gttgcttcag
     4021 caaactcggc taaaactttt gcaccaatct ctttatgggt aatcatacga cccttaaagc
     4081 gaatagatac cttaacttta tttccttttt caaggaactt acgtgcatta cgaagttttg
     4141 tatcaaagtc acccttgtca attgttggac ttagacgaac ttctttcaca gtaacaacgc
     4201 tttgtttttt acgttgttct ttttgcttct tctggtactc aaatttgaac ttaccgtagt
     4261 ccataatttt tgcaacaggc ggtttggctt ggggttgaat caatactagg tcaacattag
     4321 cgttatcagc caaagcttgc gcttcactga gtggcttgat acctagctgt tctccttcaa
     4381 gaccaatcaa gcgaacttca cgtacacgaa tctcatcatt gatgaataag tcttgctttg
     4441 ctatggtttt cacctctttt gttttattag agaaaaacaa tagcggactt gtaaatatac
     4501 aagcccgcac gttatgatag cgtttcttcg aaacttttca tccgtagggc caggcaactt
     4561 aatgtcacaa ggcgagaagc tctcacttct gcttttctca acttttatat gataccaagt
     4621 tttctagctc ttgtcaagat aaaaagttat tttttgaaaa gtttgtgttt gtattttggt
     4681 ttggttttcg aatcaaaaag agagaatcaa gttgattccc tctctatgtt agtttttact
     4741 tattttccct acctatagga aagctagaat ctattaaaaa attctttttt ctgtgaactt
     4801 ccccatcttt caataaatag aattcccaat agcaaaaaga taatcaggca aggaagtaag
     4861 accattccca tgctccaatt tagatcgaca ttatcaatct gcttaggtaa tcttccagat
     4921 aaaatctcca ctgaacgcaa gtaagtaaag ggaatcagat gtgcaatcct ttgaagaggc
     4981 tgaatggttt ggataccaaa caataagcca acaatcccaa tgagtgaaag aaagaggaca
     5041 ggcatttttt gcttgaaaaa gtaagcaatc aagtacacaa cttccacaat gacgataaag
     5101 gctaagaaag ctaagagcaa gccaggaaat aatacatctt gtattttccc aatagttact
     5161 tcttgattca ctaagctata aattgggtag ggataatcta actgtccaaa accacttatc
     5221 agacttccca ctagaaaaga aaagccacag attccgataa acagcacagt tacatatccc
     5281 actccaactc caagagagga tattgcaaat gtcacttttg aaacaggata taagtgagct
     5341 gtgtccagat gattttgata tctttctgca aatagttgtg ttagcataaa aataatagca
     5401 accacaaaca aacttgggat gataacctct aaaatccaga caatctgatc aatcccgtgg
     5461 gtcggaaact ccaaagtatg tgcttttatg ttcaagggat acagggcttg gtaaatcttc
     5521 cgttcgcggt caacccccat ttttaagcca gggctagcag tcgggtcatt tgatacaaat
     5581 tcataattct tctcttcatc ttgccactgc aaatagtagg cttctttcca gcgcccttct
     5641 tttaataaag tcagaatttc tgtctttcgc gtcaaaagat ttttttgcac gtctaaatta
     5701 tttttagcaa actggtattc ctccgagctg gtatcagaca tttgggagag tttctcttca
     5761 ttttcattga tagccctctc gttggctgca atgcgacttt ccaacctgct ctccaagctg
     5821 tgtgagtttg cagtctgact atttaaataa aaggtaacac cgagtacaga tacaaataaa
     5881 gctaagacaa tccagtttaa gcggcttttg aaaacttttt tcaataaaaa tagactaaca
     5941 tctttcataa actaaacctc ttctatctgc ccctgatgaa tggttactac tctatcgcag
     6001 acatcaacca actcttcctt atagtgggaa cttaaaagaa ccagctgttc ttgtctatcg
     6061 atttgtgcta gcctatcaaa aaacttctgt cgataatact catctaagcc atttgtaatc
     6121 tcatccatga gccagcattt ggcctgactg aggaaataca tggcaatcac caagcgttgc
     6181 ttcatgccta aggaatactt gcgaatggga agactgatat agtcagacat ttcccaatag
     6241 gcgatttcat ccctcaagtt cagacctgac ttccagatgt ttttgataag acgaaggtag
     6301 tccatcccac ttaagtttcc atccagccat tcaatactct cataataaaa taaagaagga
     6361 ggggctgcga tatttccact acttatggga attaaattgc taatggcacg gaacagggtc
     6421 gtctttccag agccattgat agcaagaaga ccataaaccc tacccttttt aaaggtgaaa
     6481 tccacatctt gcaagatgac ttgtcgcgtt tttaaggtca catgagtaag ctgcaacata
     6541 tctagccctc ctttttctca ctctttaaga attaatagcc tccgctgtaa tagtttatga
     6601 cctcataacg agcgtagttc cagcctccgc caactttata ctcagaatag ctgtcataac
     6661 gagaccatga cggaatccaa gcatactgat ggtcgtgata gttggtacta tattcccaaa
     6721 ccgtattcca atcatacttg taacttttag tgactgtcac agcagataca ctggactgaa
     6781 gaagaccaat agattataaa ctaactaata aaacaacttt tgctgatttt taatgatttt
     6841 atatcctcaa tattgaatac gttttcatta taccattttt atcattatta tgcaacaaat
     6901 ttttagttta tttcactaat ctacaacatt tatccttcct atcgaacact ttcgattttc
     6961 caactatcca accccttaaa acgtatagct ccttgctggt cagttcgata aactttgcta
     7021 ttgatacctt ccagtcgtgt caatgtttcc tgatggggga gtttcattcg attgctcttt
     7081 ccaactgaga taagagtaag ctctggtttg agtttttcta gaaaggctgg acttgatgat
     7141 tttttattgc catgttggct agctttcaaa acatttactt tcaagtctgg atagtgcttc
     7201 agcaagtcct tctctccttt ctcctccaaa tttcccgtga agagaaattg cttatccaag
     7261 aatttcccat acagaactag ggtatcatcg tgtcctccat ctcccatttt ccttggagat
     7321 agaacttcta actgacttcc aaaaatgggc aagttctccc ctactatcat actacgcacc
     7381 tttgtttgag tcgcctgtag ttctgccaca aattccttct gtttcagact gtcttttgat
     7441 actagaatct cccctacatg gaaagccttg gtcatctctg acaaatctcc aacatgctcc
     7501 ttgtccgtgt tagtcaaaat tagctggtca atcttagcta ctcctcgact tttgagatag
     7561 ggaatcaagg ttcgctgggc attgctggtc gtcatctttt cttgccattt tttgattttc
     7621 ttataagatt ctgccttacc acctacatct atgagaatgg ttttcccagt tacatcccgt
     7681 aggaaaatac tttctccttg ccccacatcc agcatggtga tttcattttc cagtggatac
     7741 ttggtaagga aaaagagacc tgtaatcaat aaactcaata ctgttaatcc tttaatgttt
     7801 ttcctcaaat catagaccaa agccaaggaa attaacaata agattaaaag ccatgcgttg
     7861 ggttgaccaa agacaagtgg tctccttgcc acctgcgaga ccaagcgaat aatgccctct
     7921 aaccattcaa agataaagtt cagctgaatg actggataga gaaaggaaag gacaaataag
     7981 atagacaaga gcggtaagaa gaccaagtca aaaagaaagg aaaagacaaa ggtcaaaagg
     8041 atagaccaag gttgaaattc cgcaaaatag aaggatagaa tgggcaatat gcccaaggag
     8101 atgactagac tttcactagt aacagccttg agcccctccc cttctttgct ggtcatggtc
     8161 aggataaaag cataagcgca ggacaagact cctcctgctg tcaagaaaaa gtttggcatg
     8221 acaataaaga ggacaagcac cgtcaaggca aaattatcca agcccttaac cccatgttga
     8281 gccagtagct tttgcaagag actgcgaata accgatgctg aaaatccagt tagtcccgca
     8341 tagataaggg aaaagggata agtcagccat ttcaactttt cttgggtcaa gcccaatcgc
     8401 aagagaagtt tcttaaatcc attcatgaaa aaacctacct gcatgccaga tagggcaaag
     8461 aggtggataa ttcctagact ggaataaagc tcattcatct cctcaaagtc ggtgtccaga
     8521 tgtcccagca agagtcctgt catgtaattg cccatagggt ctggaaagtg cgtcttaatc
     8581 caaaccacag cctttcgacg taaactggac aagttttctc ctatatccca actgccaatc
     8641 ttttgaagtg actggattgt tttgatattg agagtctggt aaattccctg agtcttcaga
     8701 taggcttggt aattaaagcc accaaaattt ctctgccctt ctggctccga aagcttccct
     8761 tctagtccta tctcatgcag gtcagttaaa gcttgaaagg cttctttctc ctcctcggac
     8821 tggagtttat aatagacttg gaaagcacga ccgttagact tgccacgaaa ggatagacta
     8881 tcaccattaa ccttaatagt atcaggcaaa atccgtaccc tttcaacaga atccgccaga
     8941 ttttgactcg cttgactctg ttgccaattt tgaaaaacaa accaaaatcc aaagattccg
     9001 caaattatta gaactttacc agcagatttc cacggaaatt ggataaagag acagactagc
     9061 agaaaaacaa agcccaacaa agcaagataa gatgctgaga aaatagcgta ataaagccaa
     9121 agtaatagaa aactcaggta aattagggga atagagaaat tcttaatcca ctgtaacata
     9181 gtctttaagc ttttctattg ttttgccacc aatgccagag accttcttga gctcgtctac
     9241 tgacttgaac ttgccatttg cctcacgatg gtcaataatg tcctgagctc gttttcctcc
     9301 cagtcccttg acctgcttga gttcttccag actggccttg ttgagattga ccttcttttc
     9361 cttgcttgtt gaagaagctg tccccgaacc agtctgttga ctaactgctt cttctccctt
     9421 agtaggaacg taaaccagag cctcatcact aactttctga gctagattga gcgacttgct
     9481 gtctgcttgc tctgtcaagc caccagcctt ctgaacagca tcattgactc gactacctac
     9541 aggcaagtca taaatccctg gcgatttgac agcacctttg acatctactg tgattagatc
     9601 ttgttcaagg ggttcttcct tttcttcctt cttcacttcc ttttcggtcg atgagtcctt
     9661 ggaaacagct gcaacttcag cctgcaaatt cgtctctttg acaggtgttt gtggagctgg
     9721 ttttagcagg aaaaatcctc ctacaagcaa gcccagacca gtacagatga cgatgatttt
     9781 atactctttg attttctcga taattgcttc catattttct cctctcttag attattcgta
     9841 agaggaagaa aaaacagtcg aaaaatttct tttcaactgc ttatttattt gcaaaatagt
     9901 cttccttggt caagacataa tgaactcttg tcacgattcg gcctttttca tgctggtcca
     9961 tacaagcata tggttctgca tgggaaaaac gcatgcctga tttctccatg acctttcctg
    10021 acgcgggatt agccttatcg tgaagggcag tcaacttatt catccctatc ttctcaaaag
    10081 ctagctcaat cacagcacga ttggcttctg tcgttaatcc ttgattccaa tactttttat
    10141 tgataatgta gccaatagct gccttcttaa gaacagaatc aatcttgtgc aagtcaatgg
    10201 ttccaataaa ctgaccattg ctttttagtt ctattcccca acgtcccaag ggattagcca
    10261 agtagaactg agcaatgtta ttcttggttt cttccaagct ttgattggtt ggaaaagtgt
    10321 aacgtgtatt acccttgtcc gaggcatagt caaacattgc ttccgcatca tccaaagtta
    10381 caggtctgag caataaacgc tccgtttcta tagacggata ctgggcaaat ttcacaaata
    10441 ttgattccat acttttccct ccattagagc ttgattttca ctagtctagc ataaaaaaat
    10501 ttggatgaca agtttttctt gatttttgaa gcggtttcat atacaatgaa accgtcacat
    10561 ttttgattta tgaactggaa tgtgacaacc aaaacaagac cgtcaattga aaggtaggtt
    10621 atctcaatgt taatcggaat cccaaaagaa attaaaaata acgaaaaccg tgtcgccctc
    10681 acacctgcag gtgttcatag cttagttagt cgtggtcatc gtgtccttat cgaaacaaat
    10741 gctggtctcg gttctggctt tactgatgct gactatcaaa agcaaggagc tgagattgtc
    10801 gctactgctg gtgaagcttg ggcagcagag ttggttgtga aagtaaaaga atctttaagt
    10861 tctgaatacg gttacttgcg cgacgatctt cttctcttca cctacttgca catggccgct
    10921 gctccagaat tagcagatgc tatgttaaca gcaaaaacaa ctgaaactgt tcgtgacaat
    10981 caaggacaac taccgctcct cgttcctatg agtgaggttg caggtcgtat ggctgttcaa
    11041 atcggagctc acttccttac taagcaagct ggtggctctg gtgttctact tggtggtgta
    11101 ccaggtgttc caaaaggaaa agtaactatc atcggtggtg gtgtcgtcgg tacacatgct
    11161 gcccgcatcg cccttggtct tggtgctcaa gtgactattt tagatattag ttccaagcgt
    11221 ctctcagttc tagaagaagt ctttggaagt caaattcaaa ctcttatgtc taattcattc
    11281 aacattgaag caagtgtgag agatgctgat gtggtgattg gagccattct catccctggt
    11341 gcaaaagcac cggaattggt gacagatgag atggtcaaac aaatgcgtcc aggctctgta
    11401 tcgttgacgt tgctgttgac caaggtggcg ttatcgaaac agctgaccgt gtgacaacgc
    11461 acgatgaacc cgtctatgaa aaacacggtg ttctccacta tgccgttgcc aatatccctg
    11521 gtgcggttgc tcgcacttca accatcgccc taaccaatgt cactcttcct tatatcgaag
    11581 ctttggctgg caaaggattc gcacaagcaa tctctgaaga tgaaggcttg cgtcaaggtg
    11641 tgactactta tcaaggttac ttgactaacc taccagttgc tcaaggactt aatcgtgact
    11701 acactgatat caatgattta gtataaattt tgaaaagaaa agggtgactt cgcaagtcct
    11761 acccactgtg ctttgtgtca tcagctatta catcgttggt ttattgtact gtatactttg
    11821 caactggaga ctttcgttcc agactcaatt gtgcataaga aactctaaat tgaataaagt
    11881 caacagagtt tcgcccaacc acttcgtctt gtaatgacaa ttatataaac caaaggaagc
    11941 tgagctcttt agtcccagct tctttttata tataaaattt tacccgtgca aagacagggc
    12001 cttagcagac ttctttttta cttcgttcac ccttgctttt tctttttagg tttgggcgtt
    12061 ggcagttggt tatacatagc taaaattagg tcttatagaa acatcttatt atcaagttct
    12121 tccactcaaa tcatttcttt ggcacctttg tatggaaact caaaagaaga ttggtcaatc
    12181 ttatctaaga ctgcttgcac gggtttaact aaaaagcgat cgtcataaat gccgccaata
    12241 atcttgccgc ggaagtaaag aatatactcc cccatcatgg aacggtaagt cacatcatct
    12301 aatcctgata attgttccaa aacaaattcc aaatagttct tacttgatgc catttctaat
    12361 cttctaggct ctgttcagcg ataacaaccg tatagagttc ttgcttaacc tcgcatccaa
    12421 ttgatttaaa gccctgcttt tcccaaaaat gctgagattg cggatttccc ttaacataag
    12481 ccaaacgtgc ctttcgaaag ttcttagcaa aataagctag tgcttctgtc acaatatgac
    12541 taccaatccc ttttctctga taggcttgat caaccataaa caaaccaata aaaacagtct
    12601 cctcatcagg atatgcatag acaaaatcca taacagccac aaggtcagat ccattccaaa
    12661 atccaacaaa aaacttatca gccttagctt taccttcagg tagacaaagc atgtcctctt
    12721 ttacagttgc aaaatttggc tctggtggac aatgctgaaa atacagagga ttactttcat
    12781 ataaagataa aatacttgga atatcctttt cagttagtat cctacaactg taatacttag
    12841 atagttggtc aatcatcttt tcaaattcct actttcttgt gccctgtgat tatgacacag
    12901 gaagatgcac tgatcgtcat cagccacata aaagttcttt ccatcgtgcc taatcgttgt
    12961 ctcagacctt tggataaaac ctttagccta tacaactgga ttttcctctc tcaaaagtat
    13021 attagacttg ttcggaatct agttcacttc ataattgatg atggcacaaa ttaattccgc
    13081 ccgtaactcg aaacgttttc tgcggttacg ataagggact gacatgattt ggaaggtctt
    13141 gaatttagcg ttaaaatgtt caatttcaat tcgtatcgct gacatctctt tatttaactg
    13201 cttatcatcc tcactcaggc ggcgattttt ggaattttta gcaggaatga aagtattctc
    13261 atgaaatttc aagatgccta aataacctag gtcaacaaag gcaagcgtcg tttcaggcaa
    13321 actttgtcca atactttctt tgaagagagt aaaatcatgc gtatgtccgt cagaaaaggc
    13381 catttgacag actttatgtg tcgtcaaatc cagcataatt tgagtttt
//
LOCUS       DAVFER010000055        12957 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1105170250
            SAMEA2167659-rid19724873.denovo.055, whole genome shotgun sequence.
ACCESSION   DAVFER010000055 DAVFER010000000
VERSION     DAVFER010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2167659
            Sequence Read Archive: ERR388902
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12957)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12957)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928716.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928716.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 04:07:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,118
            CDSs (total)                      :: 2,073
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 120
            CDSs (without protein)            :: 120
            Pseudo Genes (ambiguous residues) :: 0 of 120
            Pseudo Genes (frameshifted)       :: 67 of 120
            Pseudo Genes (incomplete)         :: 47 of 120
            Pseudo Genes (internal stop)      :: 34 of 120
            Pseudo Genes (multiple problems)  :: 23 of 120
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12957
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2167659-rid19724873.denovo.055"
                     /strain="1105170250"
                     /db_xref="taxon:1313"
     gene            87..3437
                     /locus_tag="VU534_001837"
     CDS             87..3437
                     /locus_tag="VU534_001837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000526318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HEU1514377.1"
                     /translation="MGNFSFLLKNDEYESFSKPCIEAENMIATSTVATAFMARRALEQ
                     AVHWIYSHDSYLEAPYRATLSSLVWDDDFRDIVDSELHKQIVLLIRWGNHAAHGGEIK
                     EREAILALHHLYQFVNFIDYCYSNEFVERYFDEKCLPLSANIKYRETPQSMIKLQDSL
                     PELPDFHEQMAAQSVEVQETYTEKRETAAQRQDVPFHIDQLSEAETRKLFIDIDLRLA
                     GWIFEENCRVEIAVDGLKHGSGIGYCDYVLYGKNGKILAIVEAKKASVNPEVGEVQVK
                     EYAEALEKHIGYQPICFITNGLKHYILDGPNRRQIAGFYSQEELQLVMDRRHLQKPLE
                     DISSKIRDDISGRHYQKHAIASVCEAFSDHRRQALLVMATGAGKTRTAVSLVDILSRH
                     NWVKNVLFLADRTSLVKQAYDSFRKLLPDLSVCNFLEDKEGAQSSRMVFSTYPTMIGA
                     ISGQEEVNQRPFTVGHFDLIIIDESHRSIYQKYKSIFDYFDARIVGLTATPRQDLDKN
                     TYGFFNLENGVPTYAYDLEEAVKDGYLVAYHSIETKLKLPTDGLHYDDLSEEEKEHFD
                     SKFEDNSCEKDIDGSVFNSFIFNKSTVEIVLNELMTRGIQTASGDEIGKTIIFAKNHD
                     HAEYIRGIFNNRYPEKGSDYAQVIDYSIKHYQTLIDDFKIKEKYPQIAISVDMLDTGI
                     DVPEVVNLVFFKKVRSKTKFWQMIGRGTRLCKDLFGPEQDKENFLVFDYGDNFDYFRA
                     DPRDGEGRHIVSLTQRLFNIKVDLIRELQGLQYQEDQFARAYRQQLVSELQGRIESLN
                     ELDFRVRMVLDTVYSYRKLESWQNLTAVTSETIQKNLSPLLFDEDKEDEMARRFDLWL
                     LHIQLGQLTAKSSTVHISQVMKTARALSAIGNIPQVFEQAEIIRKVQEPEFWKEVNLS
                     DLEKIRLAIRDLLQFLDKTDRKPYYVNFEDRILSTVHETTAFLQVNDLRSYNEKVEHY
                     LKTHLDEESISKLYHNKKLTSDDMLALEKLLWEKLGSKADYQSHYENKAIPRLVREII
                     GLDRESANRIFSKFLSDENLNARQISFVKLIVDYIVENGFLETKVLTQEPFKSYGSVQ
                     LLFQHQLPVLRNIVQIIELINNRAGEAA"
     gene            complement(3943..4413)
                     /locus_tag="VU534_001838"
     CDS             complement(3943..4413)
                     /locus_tag="VU534_001838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001043003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEU1514378.1"
                     /translation="MNKSEHRHQLIRALITKNKIHTQAELQALLAENDIQVTQATLSR
                     DIKNMNLSKVREEDSAYYVLNNGSISKWEKRLELYMEDALVWMRPVQHQVLLKTLPGL
                     AQSFGSIIDTLSFPDAIATLCGNDVCLIICEDADTAQKCFEELKKFAPPFFFEE"
     gene            complement(4430..6703)
                     /locus_tag="VU534_001839"
     CDS             complement(4430..6703)
                     /locus_tag="VU534_001839"
                     /EC_number="3.4.14.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Xaa-Pro dipeptidyl-peptidase"
                     /protein_id="HEU1514379.1"
                     /translation="MRFNQYSYINFPKENVLSELKKCGFDLQNTANHKDSLETFLRRF
                     FFTYQDTNYPLSILAADKKTDLLTFFQSEDELTADIFYTVAFQLLGFSYLVDFEDSDV
                     FRKETGFPIIYGDLIENLYQLLNTRTKKGNTLIDQLVSDGLIPEDNDYHYFNGKSLAT
                     FSNQDVIREVVYVESRVDTDQKGLSDLVKVSIIRPRFDGKIPAIMTASPYHQGTNDKA
                     SDKALYKMEGELEVKLPHKIELEKPQLNLVQPQGKAELIAEAEEKLTHINSSYTLNDY
                     FLPRGFANLYVSGVGTKDSTGFMTNGDYQQIEAYKNVIDWLNGRCRAFTDHTRQRQVK
                     ADWSNGKVATTGLSYLGTMSNGLATTGVDGLEVIIAEAGISSWYNYYRENGLVTSPGG
                     YPGEDFDSLAELTYSRNLLAGDYIRGNEAHQADLEKVKAQLDRKTGDYNQFWHDRNYL
                     LNAHKVKAEVVFTHGSQDWNVKPLHVYQMFHALPTHIHKHLFFHNGAHVYMNNWQSID
                     FRESINALLTKKLLGQETDFQLPTVIWQDNTAPQTWLSLDNFGGQENCETFSLGQEEQ
                     AIQNQYPDKDFERYGKTYQTFNTELYQGKANQITINLPVTKDLHLNGRAQLNLRIKSS
                     TNKGLLSAQLLEFGQKKYLQPYPAILSARTIDNGRYHMLENLCELPFRPEAQRVVTKG
                     YLNLQNRNDLLLVEDITADEWMDVQFELQPTIYKLKEGDTLRLVLYTTDFEITIRDNT
                     DYHLTVDLAQSMLTLPC"
     gene            7050..10151
                     /locus_tag="VU534_001840"
     CDS             7050..10151
                     /locus_tag="VU534_001840"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000561528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HEU1514380.1"
                     /translation="MIAQLDTKTVYSFMESVISIEKYVRAAKEYGYTHLAMMDIDNLY
                     GAFDFLEITKKYGIHPLLGLEMTVFVDDQGVNLRFLALSSVGYQQLMKLSTAKMQGEK
                     TWSVLSQYLEDIAVIVPYFDRVESLELGCDYYIGVYPETLASEFHHPILPLYRVNAFE
                     SRDREVLQVLTAIKENLPLREVPLRSRQDVFISASSLEKLFQERFPQALDNLEKLISG
                     ISYDLDTSLKLPRFNPARPAVEELRERAELGLVQKGLTSKEYQDRLDQELSVIHDMGF
                     DDYFLVVWDLLRFGQSNGYYMGMGRGSAVGSLVSYALDITGIDPVEKNLIFERFLNRE
                     RYTMPDIDIDIPDIYRPDFIRYVGNKYGSKHAAQIVTFSTFGAKQALRDVLKRFGVPE
                     YELSAITKKISFRDNLKSAYEGNLQFRQQINSKLEYQKAFEIACKIEGYPRQTSVHAA
                     GVVISDQDLTNYIPLKYGDEIPLTQYDAHGVEASGLLKMDFLGLRNLTFVQKMQELLA
                     ETEGIHLKIEEIDLEDKETLALFASGNTKGIFQFEQPGAIRLLKRVQPVCFEDVVATT
                     SLNRPGASDYINNFVARKHGQEEVTVLDPVLEDILAPTYGIMLYQEQVMQVAQRLAGF
                     SLGKADILRRAMGKKDASAMHEMRASFIQGSLEAGHTVEKAEQVFDVMEKFAGYGFNR
                     SHAYAYSALAFQLAYFKTHYPAIFYQVMLNSSNSDYLIDALEAGFEVASLSINTIPYH
                     DKIANKAIYLGLKSIKGVSNDLALWIIENRPYSNIEDFIAKLPENYLKLPLLEPLVKV
                     GLFDSFEKNRQKVFNNLANLFEFVKELGSLFGDAIYSWQESEDWTEQEKFYMEQELLG
                     IGVSKHPLQAIASKAIYPITPIGNLSENSYAIILVEVQKIKVIRTKKGENMAFLQADD
                     SKKKLDVTLFSDLYRQVGQEIKEGAFYYVKGKIQSRDGRLQMIAQEIREAVAERFWIQ
                     VKNHESDQEISRILEQFKGPIPVIIRYEEEQKTIVSPHHFVAKSNELEEKLNEIVMKT
                     IYR"
     gene            10233..11240
                     /gene="pfkA"
                     /locus_tag="VU534_001841"
     CDS             10233..11240
                     /gene="pfkA"
                     /locus_tag="VU534_001841"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000820836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HEU1514381.1"
                     /translation="MKRIAVLTSGGDAPGMNAAIRAVVRQAISEGMEVFGIYDGYAGM
                     VAGEIHPLDAASVGDIISRGGTFLHSARYPEFAQLEGQLKGIEQLKKHGIEGVVVIGG
                     DGSYHGAMRLTEHGFPAIGLPGTIDNDIVGTDFTIGFDTAVTTAMDAIDKIRDTSSSH
                     RRTFVIEVMGRNAGDIALWAGIATGADEIIIPEAGFKMEDIVASIKAGYECGKKHNII
                     VLAEGVMSAAEFGQKLKEAGDTSDLRVTELGHIQRGGSPTARDRVLASRMGAHAVKLL
                     KEGIGGVAVGIRNEKMVENPILGTAEEGALFSLTAEGKIVVNNPHKADIELSSLNKSL
                     S"
     gene            11299..12804
                     /gene="pyk"
                     /locus_tag="VU534_001842"
     CDS             11299..12804
                     /gene="pyk"
                     /locus_tag="VU534_001842"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HEU1514382.1"
                     /translation="MNKRVKIVATLGPAVEIRGGKKFGEDGYWGEKLDVEASAKNIAK
                     LIEAGANTFRFNFSHGDHQEQGERMATVKLAEKIAGKKVGFLLDTKGPEIRTELFEGE
                     AKEYSYKTGEKIRVATKQGIKSTREVIALNVAGALDIYDDVEVGRQVLVDDGKLGLRV
                     VAKDDATREFEVEVENDGIIAKQKGVNIPNTKIPFPALAERDNDDIRFGLEQGINFIA
                     ISFVRTAKDVNEVRAICEETGNGHVQLFAKIENQQGIDNLDEIIEAADGIMIARGDMG
                     IEVPFEMVPVYQKMIIKKVNAAGKVVITATNMLETMTEKPRATRSEVSDVFNAVIDGT
                     DATMLSGESANGKYPLESVTTMATIDKNAQALLNEYGRLDSDSFERNSKTEVMASAVK
                     DATSSMDIKLVVTLTKTGHTARLISKYRPNADILALTFDELTERGLMLNWGVIPMLTD
                     APSSTDDMFEIAERKAVEAGLVESGDDIVIVAGVPVGEAVRTNTMRIRTVR"
BASE COUNT         4006 a         2208 c         2853 g         3890 t
ORIGIN      
        1 gcttgtgaga tagctataaa agtgtggaga aatagcttga aatttagtat aatatagcta
       61 aactatttgt ttaaagtgag aaaaaaatgg gaaattttag ctttctttta aaaaatgacg
      121 aatatgaatc tttttcaaaa ccttgcattg aagctgagaa tatgattgct acatcaactg
      181 tggctactgc ctttatggcg cgtcgtgctt tagagcaggc tgtccattgg atatatagtc
      241 acgattcata tttagaagct ccctatcgtg ctactctatc ttctttagta tgggatgatg
      301 attttaggga tatcgtagat tctgaactcc acaagcagat agttctgttg attcggtggg
      361 gaaaccatgc tgctcatggt ggtgaaatta aggaacgaga agcgatttta gctttgcatc
      421 atttgtatca gtttgttaat tttatcgatt attgttacag caatgagttt gtggagcgtt
      481 attttgatga gaagtgctta ccactttcag caaacatcaa ataccgagaa actccacaat
      541 ctatgataaa gttacaagac agtttaccag aactgcctga ttttcatgaa cagatggctg
      601 ctcagtccgt agaagttcaa gagacttata ctgaaaaacg tgagactgca gcgcaacggc
      661 aagatgtgcc tttccatatt gatcaattat ctgaggcaga gacaagaaag ctctttattg
      721 atatcgatct ccgtttagca ggatggatat ttgaagaaaa ctgtcgtgtt gagatagccg
      781 ttgatggtct caagcacggt tcaggaattg gttactgtga ctatgtactt tatggtaaaa
      841 atgggaaaat tttagcgatt gtggaggcta aaaaagcctc tgtcaatcca gaagtagggg
      901 aagtacaggt caaagaatat gctgaagctt tggagaaaca tatcggctat cagccaattt
      961 gctttattac aaatgggttg aagcactata tacttgatgg tccgaaccgc cgccagattg
     1021 caggctttta ctctcaagaa gaattgcaat tagtgatgga tagacgtcat cttcaaaaac
     1081 cgcttgagga tatttctagt aaaattaggg acgatatttc cgggcgtcac taccaaaaac
     1141 atgccattgc aagcgtttgt gaagctttct ctgatcatcg tagacaggca cttttggtta
     1201 tggcaactgg ggcggggaaa actcgtacag cagtttctct agttgatatc ttatcacgtc
     1261 ataactgggt aaaaaacgtt ctcttcttag ccgatagaac ttccttggtt aagcaagcat
     1321 atgattcgtt tagaaaatta ctcccagatc tttccgtttg taacttctta gaagataaag
     1381 aaggagctca atcaagtcgc atggtctttt caacttatcc gaccatgatt ggagcgatta
     1441 gtggtcaaga agaagtaaat caacgccctt tcactgttgg gcattttgac cttatcataa
     1501 ttgacgaatc tcaccgttct atttatcaga aatacaagtc catttttgat tattttgatg
     1561 caagaattgt aggcttaaca gctactccgc gtcaagattt agataaaaac acctatggat
     1621 tctttaattt ggagaatggg gttccaacat atgcatatga tttggaagag gctgttaaag
     1681 acggatattt agtagcctat cattctatcg aaaccaaact gaaactacct acggatggtc
     1741 tacattatga tgatttgtcc gaagaagaaa aggaacattt tgatagcaaa tttgaagaca
     1801 atagctgtga aaaagatatt gatgggagtg tatttaattc ctttattttc aataaaagta
     1861 cagtagaaat tgttttaaat gaactcatga caagaggaat tcagacagcc tcgggtgatg
     1921 aaattggtaa aactattatt tttgctaaaa atcatgatca tgcggaatat atcagaggta
     1981 tttttaacaa ccgctatcct gaaaaaggga gcgactatgc tcaggtgatt gattatagta
     2041 ttaagcatta tcagaccttg attgatgatt ttaaaattaa ggagaagtat cctcaaattg
     2101 cgatttctgt cgatatgtta gatacaggta ttgatgtacc agaggttgtt aatttagtct
     2161 tcttcaagaa agtacgctct aaaactaagt tttggcagat gattggtcga ggaacccgtc
     2221 tatgtaaaga tttatttgga cctgagcagg ataaggaaaa cttcttggta tttgattatg
     2281 gggacaattt tgattatttt cgtgcagatc caagagatgg agagggtcgt cacattgttt
     2341 cgctgactca gcgtttattt aatatcaaag tggacttgat tcgagaactt cagggactcc
     2401 aataccaaga agatcagttt gcgagagcat accgtcagca gcttgtctcg gaacttcaag
     2461 gtcgtataga gagcttaaat gagttggact tcagggttcg tatggtttta gatacagttt
     2521 atagctatag gaaattggaa agttggcaga atctaactgc tgttacaagt gaaaccattc
     2581 aaaaaaatct ctctccgctt ttatttgatg aagataaaga agatgagatg gcgaggagat
     2641 ttgatttgtg gttgcttcat attcagttgg ggcaactgac agctaaatct tccactgttc
     2701 atatttccca agtgatgaag acggctagag ctctttctgc tattggcaat atcccgcagg
     2761 tttttgagca ggctgaaatt atcaggaaag tacaggagcc tgaattttgg aaagaagtta
     2821 acttgtctga tttggaaaaa attcgtcttg ctattcgaga tttattacag tttttggata
     2881 aaacagaccg taaaccctac tatgttaact ttgaagatcg tatactctcc actgttcacg
     2941 agaccacagc atttttgcag gtcaacgatc ttcggtctta caatgaaaaa gttgagcatt
     3001 atttgaaaac tcatctggat gaggagtcca tttctaagct ataccataat aaaaagttga
     3061 catctgatga tatgcttgca cttgaaaaat tgctttggga aaaattaggt agtaaagcag
     3121 actaccaaag tcattatgaa aataaggcaa ttccgagatt ggttcgtgag attattggct
     3181 tagatagaga gtctgccaat cgtatttttt ctaaattttt gtcggatgag aatcttaatg
     3241 ccaggcagat ttcatttgta aaattgattg tagactacat tgtagaaaat ggttttttag
     3301 agacgaaagt gttaacgcaa gagccgttta aatcttatgg ttctgttcaa ctactcttcc
     3361 aacaccaact accagtactt cgtaatattg ttcaaatcat tgaacttatc aataatcgag
     3421 ctggagaagc ggcttaaatt ctaaagtgat tgccatgctg agactcattt aaaattaaaa
     3481 agagtagaaa tttatgctat atatgagaag ttttattagg aagaatgtca tcgttttcct
     3541 agaatacagt atcagttgtt aagtggttga taaatttcaa agtagatact tgtaccacga
     3601 tgtttgttga tcgagttatt aacaaaagag ctactttgat tttaaagaaa tagaaaacaa
     3661 aaagccgagc aagaattcaa ttgcaggaga aaatgaaata atactcaatg aaaatcaaag
     3721 agcaaactag gaaactagct gcaggctgct caaaacactg ttttgaggtt gcagatggaa
     3781 gctgacgcgg attgaagaga ttttcgaaga gtataaatct tcctaggata aagcaaaacg
     3841 catagtatca agggttttca acacttgata ctatgcgttt tctgatgtta aagactttct
     3901 accaggtttt ttaaaagcat aattgttagt tgtagtcatt tattattctt caaagaaaaa
     3961 tggtggggcg aattttttca gttcttcaaa gcacttttga gcagtatctg catcttcaca
     4021 gatgataaga cagacatcat taccacaaag ggtagcgata gcgtcaggga agctcaaagt
     4081 atcaatgata gaaccaaagg attgagccag tccaggaagg gtttttagta ggacttggtg
     4141 ttgaactggg cgcatccaga caagggcgtc ttccatgtag agttcgagac gtttttccca
     4201 ttttgagatg gaaccattgt taagaacata ataagcgcta tcttcttcgc ggacttttga
     4261 taggttcata tttttgatgt cgcgtgagag ggttgcctgg gttacttgaa tgtcgttctc
     4321 agcaagaagg gcttgcaact cagcctgtgt atgaatcttg ttttttgtga taagagcgcg
     4381 tataagttgg tggcggtgtt ctgatttatt cataataatg taactccttt tagcaaggta
     4441 aggtaagcat ggactgagcg aggtcgacag tcaagtggta gtctgtattg tcacggatgg
     4501 tgatttcaaa gtcagtagta tagaggacta aacggagagt gtctccttct tttagcttgt
     4561 aaatagttgg ctgcagttca aattgaacgt ccatccattc atctgcagta atatcctcta
     4621 ctaacagtaa atcatttcta ttttgtaaat taaggtaacc ttttgtcacg actcgttgtg
     4681 cctctggtct aaatggcaat tcacagagat tttccaacat gtgatagcga ccgttgtcaa
     4741 tggttctagc acttaaaata gctggataag gttgtaggta tttcttttgc ccaaattcta
     4801 gcagttgggc agataagagc cccttgtttg tactggattt gatacgaaga ttgagctgag
     4861 cgcgaccgtt taggtggaga tctttagtca caggaaggtt aatagtaatc tgattggctt
     4921 tcccttgata gagctctgta ttgaaggttt ggtatgtctt accatagcgc tcaaaatcct
     4981 tatctgggta ctggttttga atagcttgct cttcttgacc aagtgagaag gtttcacagt
     5041 tttcttgccc accgaagtta tcaagtgata accaagtctg tggagctgta ttgtcctgcc
     5101 agataacagt aggaagttga aagtctgttt cctgtcctag taatttcttg gtcaataagg
     5161 catttatgga ctcacggaag tcaattgatt gccaattgtt catgtaaaca tgggcaccat
     5221 tatggaaaaa gagatgcttg tgtatatgag taggaagagc atggaacatc tggtaaacat
     5281 gaagtggttt gacattccaa tcctgagaac catgagtaaa gacaacctct gcctttactt
     5341 tatgggcatt gagcagataa ttgcggtcat gccaaaactg attgtagtcc ccagtttttc
     5401 ggtctagctg agctttcact ttttctaagt cagcttggtg agcttcattg ccacggatat
     5461 agtcgccagc taagagatta cgagaatagg ttaactcagc aagggagtca aagtcctcac
     5521 ctggataacc acctgggcta gtcaccagac cgttttcacg gtagtagttg taccatgatg
     5581 aaattcctgc ctcggcaatg ataacttcta aaccatcgac tcctgtagtc gcaagaccat
     5641 tggacatggt acctagatag gaaagtcctg ttgtagcaac ttttccgttt gaccaatcag
     5701 ccttgacttg acgctggcgc gtgtgatcag taaaggcacg gcaacgaccg ttaagccaat
     5761 cgatgacatt tttataagcc tcgatttgct ggtagtctcc attagtcatg aaacctgtcg
     5821 agtctttggt accaacacct gagacataga gattggcaaa gcctctcgga aggaagtagt
     5881 cgtttagtgt atagctagag ttgatgtgag ttagcttttc ctcagcctct gctataagct
     5941 cagctttacc ttggggttgg acgagattta gttgaggttt ctctagctca atcttgtgag
     6001 gaagcttaac ctcaagctcg ccctccatct tgtagagagc cttgtcacta gccttgtcat
     6061 tggttccctg atgataaggg ctggctgtca tgatggcagg gatttttcca tcaaaacgag
     6121 ggcgaataat gctaaccttt actaggtctg atagcccttt ttggtcagta tcgacacgag
     6181 actcaacgta aacgacttca cgaatgacat cctggttaga aaaagtagcc aaactcttgc
     6241 cgttaaagta gtggtagtca ttatcctccg gaataagacc atcactaaca agttggtcga
     6301 taagagtatt tccttttttg gtgcgagtat tgagtaactg atagagattt tcaatcaagt
     6361 caccatatat aatgggaaat ccagtttctt tacgaaaaac gtcactatct tcgaagtcaa
     6421 ccaaataaga aaagcctaaa agttgaaaag caacagtata aaaaatatct gctgtcagtt
     6481 catcttctga ttgaaaaaat gtcagcaggt ctgttttttt atcagctgct aggatagaaa
     6541 gtgggtagtt ggtgtcttga taagtgaaaa agaaacgacg taaaaaggtt tcaagtgagt
     6601 ctttgtgatt ggctgtattt tgtaaatcaa agccacattt ttttagttca gataagacat
     6661 tttcttttgg aaaattgata taactatatt gattaaaacg catagaacct ccatatagaa
     6721 tgacagttaa ggttattata tcaaaaaaaa agcagaaagg gaattgttaa cttcaaaagg
     6781 aaataatcca ataaaaatga ataaagtact aaattcaata tagagaacag agtaacaata
     6841 agaataaata gatagggtat aaaagttcta ggagatttat attatatgct ttctattttt
     6901 atatacaata tagtataaat ataaaaatga tgacaaaaat acaaatgaat agaaaataaa
     6961 ttagtaagct gatgaaattt ttctcaagag aagccattta taggtgaaaa tggtataata
     7021 tagtgagaag gatagaggag aagtgtaaat tgatcgcaca actagataca aaaacagtct
     7081 atagttttat ggaaagcgtc atttcgatcg aaaagtatgt gagagcagct aaagaatacg
     7141 gctacactca tttggctatg atggatattg acaatcttta tggcgctttc gactttctag
     7201 agattacaaa aaaatacggc attcatcctt tgctagggct tgaaatgaca gtgtttgtag
     7261 atgatcaggg agtgaatttg cgctttttag ctctatctag tgtgggctat cagcagttga
     7321 tgaagctttc gacagccaag atgcaggggg agaaaacttg gtcagtcctg tcccagtacc
     7381 tggaggatat cgcggtcatt gtgccttatt ttgatagagt tgagtcgtta gaactaggct
     7441 gtgattacta tataggggtt tatccagaaa cactagcaag cgaatttcat catcctatct
     7501 tacctcttta tcgggtcaac gcttttgaaa gcagggatag agaagttctt caagttttaa
     7561 cagcgattaa agaaaatcta ccgctcagag aagttccctt gcgttcgaga caagatgtct
     7621 ttatatcagc aagttcttta gagaaactat tccaagagcg ttttccgcaa gctttggaca
     7681 atttagaaaa gcttatttca ggcatttctt acgacttgga tactagtctg aaactgcctc
     7741 gttttaatcc agctagacca gcagtagagg agttgagaga gcgtgctgaa ctggggcttg
     7801 ttcagaaggg gttgactagt aaagaatatc aagatagact agaccaagaa ttgtctgtta
     7861 ttcatgatat gggctttgat gattatttct tggttgtttg ggatttgttg cgttttggac
     7921 aatcgaatgg ctattatatg ggaatgggaa ggggttctgc agtaggcagt ttggtttctt
     7981 atgccttaga catcacgggg attgacccag tagagaaaaa tctgattttt gaacgctttc
     8041 ttaatcgtga acgctatacc atgcctgata ttgatattga tatcccagat atttatcgtc
     8101 cagattttat cagatatgtt ggtaataaat atggtagtaa acatgcggca caaatcgtta
     8161 ctttttcaac ctttggagcc aagcaagctc ttcgagatgt cttgaaacgc tttggtgtgc
     8221 cagagtatga attatctgca attactaaga aaatcagttt tcgtgacaat cttaagtcgg
     8281 cctatgaggg aaatctccag tttcgtcagc aaatcaatag taagttagaa taccaaaaag
     8341 cttttgagat tgcttgcaag atagagggct atccaaggca aacctctgtc catgcggctg
     8401 gtgttgtaat tagtgaccaa gatttaacca actacattcc tctaaagtat ggtgatgaaa
     8461 ttccactgac tcagtatgat gctcatggag ttgaggctag cggacttttg aagatggact
     8521 ttctgggact acgaaatttg acctttgtcc agaagatgca agagttgctt gctgaaacag
     8581 aaggtattca tctgaaaatt gaagaaatcg atttagaaga caaagaaacg ttagctttat
     8641 ttgcctctgg taatacaaaa ggtatctttc aatttgagca accaggtgcc attcgtctgc
     8701 ttaagcgtgt gcaaccagtc tgttttgaag atgtcgtcgc gactacttct ctaaatcgac
     8761 cgggtgctag tgactatatc aataattttg tggcaagaaa gcatgggcag gaagaagtga
     8821 ctgttctgga tccagtactg gaggatattt tggctccaac ctacggcata atgctctatc
     8881 aggagcaggt tatgcaggtt gcccagcgac ttgccggatt tagtcttggg aaagccgata
     8941 ttttgcgtcg ggctatgggg aaaaaggatg cctctgccat gcatgagatg agggcttcct
     9001 ttattcaagg ttcattagaa gctggtcata ctgtggaaaa agcagagcag gtctttgatg
     9061 ttatggagaa gtttgcaggt tatggtttta acaggtcaca cgcctatgcc tactcagcct
     9121 tggccttcca gttggcttat ttcaaaacgc attatccagc cattttttat caggtcatgt
     9181 taaattcttc caacagtgat tacttaatag atgcacttga agcaggtttt gaagtagcct
     9241 ctctatccat caacaccatt ccctatcacg ataaaattgc caacaaggcc atctatctag
     9301 gtttgaaatc cattaaagga gtcagtaatg atttagctct ctggattatt gaaaatagac
     9361 cttattctaa cattgaagat tttatagcta aattacctga gaattatctg aaacttcctc
     9421 tgctagaacc tttggtaaaa gttggtcttt tcgattcatt tgaaaaaaat cgtcaaaaag
     9481 tatttaataa cttagctaat ctatttgaat ttgtgaaaga gttgggaagt ttgtttggag
     9541 atgctattta tagttggcag gaatcggaag attggacgga acaagaaaaa ttttatatgg
     9601 aacaagagct tttagggata ggtgtcagca aacatccact acaagctatt gcaagtaagg
     9661 ctatttaccc gattacccca atcggaaatt tgtcagaaaa tagctatgct attatcttgg
     9721 ttgaagttca gaaaataaaa gtgattcgta ccaaaaaggg tgaaaatatg gccttcttac
     9781 aggcagatga tagtaagaaa aaattggatg tcactctctt ttcagactta tatcgtcagg
     9841 ttggacagga aataaaagag ggagccttct actatgtaaa aggaaaaata caatcacgtg
     9901 atggccgtct gcaaatgatt gcacaagaaa taagagaagc agttgctgaa cgcttttgga
     9961 tacaggtgaa aaatcatgaa tcggatcaag aaatttcacg cattttagaa caatttaaag
    10021 gcccaatccc agtcatcatc cggtatgaag aggaacagaa aaccatcgtt tctccccatc
    10081 attttgtagc taaatccaat gaattagagg agaaattgaa tgaaatcgtt atgaaaacga
    10141 tttatcgcta aaaatacgga aaatagaaga attttcaacg taaatgtggt ataatcagta
    10201 agaatgttaa aagaaaaagg agcataacca atatgaaacg tattgctgtt ttgactagtg
    10261 gtggagacgc ccctggtatg aacgctgcca tccgtgcagt tgttcgtcaa gcaatttcag
    10321 aaggaatgga agtttttggt atctatgacg gatatgctgg tatggttgcc ggtgaaattc
    10381 atcccctaga tgcagcttca gtaggggaca tcatttctcg tggtggtact ttccttcact
    10441 cagctcgtta cccagagttc gctcaacttg aagggcaact taaagggatt gagcaattga
    10501 aaaaacacgg aattgaaggt gtagttgtta tcggtggtga cggatcttac cacggcgcta
    10561 tgcgtttgac tgaacatggc ttcccagcta ttggtcttcc aggtacaatc gataacgata
    10621 tcgttggtac tgactttaca atcggttttg acacagcggt tactactgcc atggacgcta
    10681 tcgataagat tcgtgataca tcatcaagtc accgtcgtac ttttgtaatc gaagttatgg
    10741 gacgtaacgc tggtgatatc gctctttggg ctggtattgc aactggtgct gatgaaatca
    10801 tcatccctga agcaggcttc aagatggaag atatcgtagc aagcatcaaa gctggttatg
    10861 aatgtggtaa aaaacacaat attatcgtct tagctgaagg tgtgatgtca gcggctgaat
    10921 ttggtcaaaa acttaaagaa gctggagata caagcgacct tcgtgtaaca gaacttggac
    10981 atattcaacg tggtggttct ccaactgcgc gtgaccgtgt tttggcgtca cgtatgggtg
    11041 cacatgctgt taaacttctt aaagaaggta tcggtggtgt tgcggttggt attcgtaacg
    11101 aaaaaatggt tgaaaatcca attcttggta ctgcagaaga aggggcattg tttagcctta
    11161 ctgcagaagg taagattgtg gttaacaacc cacacaaagc cgatattgag ctatctagct
    11221 tgaataagag cttgtcataa tttacaattt agttaataag accaaaaagg tcatatatat
    11281 aaaggagtca caaaaatcat gaacaaacgt gtaaaaatcg ttgcaacttt gggtcctgcg
    11341 gtagaaatcc gtggtggtaa aaaattcggt gaggacggat actggggtga aaaacttgat
    11401 gttgaagctt cagctaaaaa cattgctaaa ttgattgaag ctggtgctaa cacattccga
    11461 ttcaacttct cacacggcga ccaccaagaa caaggtgagc gtatggcaac tgttaaactt
    11521 gcggaaaaaa ttgcaggtaa aaaagttggt ttccttcttg atacaaaagg acctgaaatc
    11581 cgtacagaat tgttcgaagg tgaagctaaa gaatattcat acaaaactgg tgaaaaaatt
    11641 cgtgttgcaa ctaaacaagg aatcaaatca actcgtgaag tgattgcgtt gaacgttgct
    11701 ggtgctcttg atatctatga tgatgttgaa gttggtcgtc aagttttggt tgacgatggt
    11761 aaacttggtc ttcgtgtggt tgctaaagat gatgcaactc gtgaatttga agttgaagtt
    11821 gaaaacgatg gtatcatcgc taaacaaaaa ggtgtgaaca tccctaacac taaaattcct
    11881 ttcccagctc ttgctgaacg cgataacgac gatatccgtt tcggtcttga acaaggtatc
    11941 aacttcatcg caatttcatt cgtacgtact gcaaaagatg tgaacgaagt tcgtgcaatc
    12001 tgtgaagaaa ctggaaacgg acatgttcaa ttgttcgcta aaatcgaaaa ccaacaaggt
    12061 atcgataact tagatgaaat catcgaagca gctgatggta ttatgattgc tcgtggtgat
    12121 atgggtatcg aagtaccgtt cgaaatggtt ccagtttatc aaaaaatgat tatcaagaaa
    12181 gtcaatgctg caggtaaagt tgttatcact gcaacaaaca tgcttgaaac aatgactgaa
    12241 aaaccacgtg caactcgttc agaagtatca gatgtattca acgctgttat cgacggaact
    12301 gacgctacaa tgttgtcagg cgagtctgca aacggtaaat acccactcga gtcagtaact
    12361 acaatggcta caatcgacaa gaacgctcaa gctcttctta atgaatacgg acgtcttgat
    12421 tcagattcat ttgagcgtaa ctctaagaca gaagtaatgg cttctgctgt taaagatgct
    12481 actagctcaa tggatatcaa attggttgta actcttacta agacaggtca tactgcacgt
    12541 ttgatttcta aataccgtcc aaatgctgac atcttagcat tgacatttga cgaattgaca
    12601 gaacgtggct tgatgttgaa ctggggtgtt atcccaatgt tgacagatgc tccatcttca
    12661 actgacgata tgttcgaaat cgctgaacgt aaagcggtag aagcaggtct cgttgagtca
    12721 ggcgatgata tcgttatcgt tgctggtgtg ccagtaggag aagctgttcg cacaaacaca
    12781 atgcgtatcc gcacagtacg ttaagaaaaa tataaaaacc tatcatatcc agctttagag
    12841 cttgtgtgat aggctttttg tatagagggt aagaaatagg caaaactttc ataatggatt
    12901 gatactcttc gaaaatctct tcaaaccacg tcagcgtcgc cttaccgtat atatgtt
//
LOCUS       DAVFER010000056        12453 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1105170250
            SAMEA2167659-rid19724873.denovo.056, whole genome shotgun sequence.
ACCESSION   DAVFER010000056 DAVFER010000000
VERSION     DAVFER010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2167659
            Sequence Read Archive: ERR388902
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12453)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12453)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928716.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928716.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 04:07:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,118
            CDSs (total)                      :: 2,073
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 120
            CDSs (without protein)            :: 120
            Pseudo Genes (ambiguous residues) :: 0 of 120
            Pseudo Genes (frameshifted)       :: 67 of 120
            Pseudo Genes (incomplete)         :: 47 of 120
            Pseudo Genes (internal stop)      :: 34 of 120
            Pseudo Genes (multiple problems)  :: 23 of 120
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12453
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2167659-rid19724873.denovo.056"
                     /strain="1105170250"
                     /db_xref="taxon:1313"
     gene            complement(70..428)
                     /locus_tag="VU534_001843"
                     /pseudo
     CDS             complement(70..428)
                     /locus_tag="VU534_001843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix domain-containing
                     protein"
     gene            complement(531..668)
                     /locus_tag="VU534_001844"
                     /pseudo
     CDS             complement(531..668)
                     /locus_tag="VU534_001844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            complement(1052..2248)
                     /gene="tuf"
                     /locus_tag="VU534_001845"
     CDS             complement(1052..2248)
                     /gene="tuf"
                     /locus_tag="VU534_001845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014335040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HEU1514383.1"
                     /translation="MAKEKYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLARRLPSSV
                     NQPKDYASIDAAPEERERGITINTAHVEYETEKRHYAHIDAPGHADYVKNMITGAAQM
                     DGAILVVASTDGPMPQTREHILLSRQVGVKHLIVFMNKVDLVDDEELLELVEMEIRDL
                     LSEYDFPGDDLPVIQGSALKALEGDSKYEDIVMELMNTVDEYIPEPERDTDKPLLLPV
                     EDVFSITGRGTVASGRIDRGIVKVNDEIEIVGIKEETQKAVVTGVEMFRKQLDEGLAG
                     DNVGVLLRGVQRDEIERGQVIAKPGSINPHTKFKGEVYILTKEEGGRHTPFFNNYRPQ
                     FYFRTTDVTGSIELPAGTEMVMPGDNVTIDVELIHPIAVEQGTTFSIREGGRTVGSGM
                     VTEIEA"
     gene            complement(3170..4039)
                     /locus_tag="VU534_001846"
     CDS             complement(3170..4039)
                     /locus_tag="VU534_001846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000348128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HEU1514384.1"
                     /translation="MDFTWALKYATEFLGTAILIILGNGAVANVELKGTKGHQSGWIV
                     IAVGYGMGVMIPALMFGNVSGNHINPAFTLGLAVSGLFPWAQVVPYIIAQVLGAIFGQ
                     ALVVATYRPFYLKTENPNNILGTFSTISSIDHGTKESRYAATVNGLINEFVGSFVLFF
                     AALGLTKNFFGAEVLQFMKQKATEAGQTVDFSDLAIKAQVAPHTASGLSVAHLALGFL
                     VMALVTSLGGPTGPALNPARDLGPRLLHAFLPKSVLGEHKGDSKWWYSWVPVVAPIAA
                     AIAAVAVFKFLYL"
     gene            complement(4263..4871)
                     /locus_tag="VU534_001847"
     CDS             complement(4263..4871)
                     /locus_tag="VU534_001847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEU1514385.1"
                     /translation="MVPKTATSTETKTITRIIHYVDKVTNQNVKEDVVQPVTLSRTKT
                     ENKVTGVVTYGEWTTGNWDEVISGKIDKYKDPDIPTVESQEVTSDSSDKEITVRYDRL
                     STPEKPIPQPNPEHPSVPTPNPELPNQETPTPDKPTPEPGTPKTETPVNPDPEVPTYE
                     TGKREELPNTGTEANATLASAGIMTLLAGLGLGFFKKKEDEK"
     gene            complement(4829..5935)
                     /locus_tag="VU534_001848"
     CDS             complement(4829..5935)
                     /locus_tag="VU534_001848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001021424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MucBP domain-containing protein"
                     /protein_id="HEU1514386.1"
                     /translation="MNIILIAKLLRENTNTKANALNNGWARSGSEEFKKFSHFVGVDK
                     GIVRTNVLTGKKLSDKIRKEVGSGDSKLGKGGYFSTGDVLLGKDVVSYTVQVFSENNE
                     RVGVNTQSHRVQYNLPILADFSVIQDTVEPSRTVVEKIIPKLNIPEEEKGKITEEIKK
                     KKKTSELAELISENVKVRYVDEQGRLLSLKNDTGIGEKESDGTYITNKKQLIGTSYNV
                     TDKKLSSMTTTDGKYYTFKEADTNSASLTGNIVSEGRTVTLVYRESEAPTTATVTANY
                     YKEGRQEKLVESVIKADLAIGSEYTTESKTIEGKTTTEDKEDRVITRKTTYTLVATPA
                     NAYQKTVQQLTITTVRMLRKQWFPKQQPLLRRRL"
     gene            complement(6046..6300)
                     /locus_tag="VU534_001849"
     CDS             complement(6046..6300)
                     /locus_tag="VU534_001849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1514387.1"
                     /translation="MLNVDQDFMSISKSNKSGSDWKKTFTVRITNRLANDLNNVLKQV
                     DKDTPNTPTWLNSAASKAKDDDRVYKLLKTLIPGENYLSC"
     gene            complement(6658..7104)
                     /locus_tag="VU534_001850"
     CDS             complement(6658..7104)
                     /locus_tag="VU534_001850"
                     /inference="COORDINATES: protein motif:HMM:NF024751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU1514388.1"
                     /translation="MDETGIDRYLYRPYAGAPRGEKVYEKISGRRFERTSIVAGQVDG
                     EFIAPMIYKKSMTSDFFVEWFKTQLLPALKTPHVIVMGNAGFHPKNILDELCIQDKHF
                     FLPLPPYSPDLNPIEQAWAILKKKVTDVLREVPTIFECLECFFKTR"
     gene            complement(7177..7502)
                     /locus_tag="VU534_001851"
                     /pseudo
     CDS             complement(7177..7502)
                     /locus_tag="VU534_001851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331855.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            7736..9454
                     /locus_tag="VU534_001852"
     CDS             7736..9454
                     /locus_tag="VU534_001852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HEU1514389.1"
                     /translation="MSYQENYQKWVDFVELPDYLRQDLENMDEKTKEDAFYTNLEFGT
                     AGMRGLVGAGTNRINIYVVRQATEGLARLIESKGGNEKERGVAIAYDSRHFSPEFAFE
                     SAAVLAKHGIKSYVFESLRPTPELSFAVRHLNCFAGIMVTASHNPAPFNGYKVYGEDG
                     GQMPPHDADALTTYIRAIENPFAVEVADVETEKASGLIEVIGEAVDIEYLKEVKDINI
                     NPALIEEFGKDMKIVYTPLHGTGEMLARRALAQAGFDSVQVVEAQATADPDFSTVTSP
                     NPESQAAFALAEELGRQVGADVLVATDPDADRVGVEVLQKDGSYLNLSGNQIGAIMAK
                     YILEAHKNAGTLPENAALCKSIVSTDLVTKIAESYGATMFNVLTGFKFIAEKIQEFEE
                     KHNHTYMMGFEESFGYLIKPFVRDKDAIQAVLVVAELAAYYRSRGLTLADGIEEIYKE
                     YGYYAEKTISVTLSGVDGAEQIKAIMAKFRNNAPTEWNATAITVVEDFKAQTATVADG
                     TVTNLTTPPSDVLKYTLADGSWIAVRPSGTEPKIKFYIAVVGETNEESQAKIANIEAE
                     INAFVK"
     gene            9565..9912
                     /locus_tag="VU534_001853"
     CDS             9565..9912
                     /locus_tag="VU534_001853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000434646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HEU1514390.1"
                     /translation="MEQFLDNIKDLEVTTVVRAQEALDKKETATFFIGRKTCPYCRKF
                     AGTLSGVVAETKAHIYFINSEEPSQLNDLQAFRSRYGIPTVPGFVHITDGQINVRCDS
                     SMSAQEIKDFAGL"
     gene            complement(10191..11027)
                     /locus_tag="VU534_001854"
     CDS             complement(10191..11027)
                     /locus_tag="VU534_001854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEU1514391.1"
                     /translation="MKKWMLVLVSLMTALFLVACGKNSSETSGDNWSKYQSNKSITIG
                     FDSTFVPMGFAQKDGSYAGFDIDLATAVFEKYGITVNWQPIDWDLKEAELTKGTIDLI
                     WNGYSATDERREKVAFSNSYMKNEQVLVTKKSSGITTAKDMTGKTLGAQAGSSGYADF
                     EANPEILKNIVANKEANQYQTFNEALIDLKNDRIDGLLIDRVYANYYLEAEGVLNDYN
                     VFTVGLETEAFAVGARKEDTNLVKKINEAFSSLYKDGKFQEISQKWFGEDVATKEVKE
                     GQ"
     gene            complement(11040..11669)
                     /locus_tag="VU534_001855"
     CDS             complement(11040..11669)
                     /locus_tag="VU534_001855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000891751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEU1514392.1"
                     /translation="MLELRNINKVFGDKQILSNFSLSIPEKQILAIVGPSGGGKTTLL
                     RMLAGLETIDSGQIFYNGQPLELDELQKRNLLGFVFQDFQLFPHLSVLENLTLSPVKT
                     MGMKQEEAEKKASGLLEQLGLGGHAEAYPFSLSGGQKQRVALARAMMIDPEIIGYDEP
                     TSALDPELRLEVEKLILQNRELGMTQIVVTHDLQFAENIADVLLKVEPK"
     gene            complement(11679..12320)
                     /locus_tag="VU534_001856"
     CDS             complement(11679..12320)
                     /locus_tag="VU534_001856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEU1514393.1"
                     /translation="MSYLFEILPSLLNGASTTVQVFALVLLFSIPLGVLIAFALQVHW
                     KPLHYLINIYIWVMRGTPLLLQLIFIYYVLPSIGIRLDRLPAAIIAFVLNYAAYFAEI
                     FRGGIDTIPRGQYEAAKVLKFSPFDRVRYIILPQVTKIVLPSVFNEVMSLVKDTSLVY
                     ALGISDLILASRTAANRDASLVPMFLAGAIYLILIGIVTIISKKVEKKYSYYR"
BASE COUNT         3641 a         2583 c         2268 g         3961 t
ORIGIN      
        1 aagttaattt cataataaaa acaccccaaa agttagattt tttctgtcta acttttgggg
       61 tgcagttcac ttgtcttctt gaattgagac tttattttta gacgcgacaa tggtttgagc
      121 atctgctttc ttaggatgtt ctggacgtgg cgtaatattt cgccaaccat ggcgcttcaa
      181 cagttgatag aaggcatcac gtgtgtagga acgacctaac tcctttttat aagcctgaaa
      241 taaggcatca attgtaacaa attctcctgc ctctgtagcc ttcaaatggc gggcaagaaa
      301 gactttctct tgctcaaccg tcatataagc atggttacga ccaccacgtg tttcttgaag
      361 gagagagtcg agtccgaact cctcatattt tttacatttc gccaaatcgt tgtttgatta
      421 cagtctaaag tgtattgaat ctataacagt acaccttggc tgctaaaata tttctataaa
      481 ttagtttgac tttcctgata gagttgttca catcttattt caaaccacta taaaagttct
      541 ataatctctt tataagattt gcccatcaga cgaaatagaa cgatttgaag gcgtttatga
      601 tatttagctg tacgagagtc ttttaaaagt gttttgatgg tttggatttc ttctttaatt
      661 gatttcatat tactattgta taatgctttt tgattttagt ctagtattat actcttcgaa
      721 aatctcttca aaccgcgtca gcttcgcctt gtcgtataga tgttactgac ttcgtcagtt
      781 ctatctacaa cctaaaaaca atgttttgag cagtctgtag ctaactttct atagtaaaat
      841 gaaataagaa caagacaaat cgatcaggac agtcaaatcg atttctaaca atgttttaga
      901 agtagatgtg tactattcta gtttcaatat attatagttt gctctttgat tttcattgag
      961 tattagttca atatctaaaa aaagaacctt gccaagcaag attcttttag tgtctaactt
     1021 aaataattgt tcttctggga actaaatcga attaagcttc gatttctgta accatacctg
     1081 aaccaacagt acgtccaccc tcacggatag agaatgtagt accttgttct acggcgattg
     1141 ggtgaatcaa ctcaacgtcg attgtcacgt tatcaccagg cattaccatt tcagtacctg
     1201 ctggaagttc gattgaacct gtaacgtcag tagtacggaa gtagaattgt ggacggtagt
     1261 tgttgaagaa tggagtgtga cgtccacctt cttctttagt aaggatgtag acttcacctt
     1321 tgaatttagt gtgtgggttg attgaacctg gtttagcgat aacttgtcca cgttcgattt
     1381 catcacgttg aacaccacga agaaggacac ctacgttatc tccagcaaga ccttcgtcaa
     1441 gttgtttacg gaacatttca acaccagtaa caactgcttt ttgagtttct tctttgatac
     1501 caacgatttc gatttcgtcg ttgactttaa cgataccacg gtcgatacgt cctgaagcaa
     1561 ctgtaccacg tccagtgatt gagaatacgt cctcgactgg aagaagcaat ggtttgtcag
     1621 tgtcacgttc tggttctggg atatactcat caactgtgtt catcaattcc ataacgatgt
     1681 cttcgtattt agagtcacct tcaagagctt taagtgctga accttggata actggaagat
     1741 cgtcacctgg gaagtcgtat tctgacaata ggtcacggat ttccatttca accaattcaa
     1801 gcaattcttc gtcgtcaacc aagtcaactt tgttcatgaa gacgataagg tgtttaacac
     1861 caacctgacg tgaaagaagg atgtgctcac gagtttgtgg cattggtccg tcagttgaag
     1921 ctactacaag gatagctccg tccatttgag cagcaccagt gatcatgttt ttaacgtagt
     1981 ccgcgtgtcc tggagcgtcg atgtgagcgt agtgacgttt ttcagtttcg tactcaacgt
     2041 gcgcagtgtt gatagtgata ccgcgttcgc gttcttctgg agcagcatcg atagacgcat
     2101 agtctttagg ttggttaact gatgaaggca agcgacgtgc caaaacagtt gtgatagctg
     2161 cagttagggt agttttaccg tggtcaacgt gtccgatagt accaatgtta acgtgtggtt
     2221 tactacgatc gtatttttct tttgccattt gagtaaaagc ctccaataaa atatatttta
     2281 tagatagaca gtaggcaata cagtctaact ttccttacta ttttatcaaa tttcagctaa
     2341 attgcaagtg ttttacaacg tttttgtgaa ttattcttgg taaaaattta actaattaat
     2401 agaaagtact aaatagactt atccttcaag gagttttcag cattatccat ccactcactt
     2461 gctgaaaatg taaacagtct ctggtttata tagtaaaatg aaacaagaat agggcaaatc
     2521 gttcaggaca gtcaaatcga tttctaacaa tgttttagaa gtagatgtgt actattctag
     2581 tttcaatcta ctatacaacc tcaaaactgt gttttgaaca acctgcggct agcttcttag
     2641 tttgcccttt gattttcatt gagtataaaa ttgcagataa aacgataaca atcataggac
     2701 tcagcagagt caatgtaggt cgaagaatag cccccctaat cgcttatttt atagtaaaat
     2761 gaaatagaaa ctgaacattt tgttgaggaa ggtaaatcaa ttcctcacaa tgtttgagaa
     2821 agaagggagg actattccaa cttcaaccca ctataaagca gacttacaag atagggaacc
     2881 catctccgat aatattccga taatatatag tagaatgaaa actgcacaat ttgattggag
     2941 aattcaaacc aatttctcac aatgttttag aaacaagggt ctattatttc aactgcaacc
     3001 tactatagtc cattgaagct ggaatagccc actgagactt ctaaaccact gctggagagg
     3061 agtttgttta gagtttcttt catttcccta aaaaatcaaa aagagagaac cagtctgatc
     3121 ctctcttact tatagatggt gctcactcaa atgttaaagg agctatttct tagagataaa
     3181 ggaatttgaa tacagctact gccgcaattg ctgctgcgat aggtgctact actggtaccc
     3241 aagaatacca ccattttgaa tcgcctttat gctcaccaag aactgatttg ggaaggaaag
     3301 catgaaggag acgtggtccc aagtcacggg ctgggttcaa ggcaggtcct gtaggtcctc
     3361 caagtgatgt taccaaagcc ataacgagga atccaagtgc caagtgagcc acagaaagtc
     3421 ctgaagcagt gtgtggagcc acctgtgctt taatagccaa gtcagaaaaa tcaactgttt
     3481 gtcctgcttc tgttgccttt tgtttcatga attgaagcac ttcagcacca aagaagtttt
     3541 tagtcaaacc aagagctgca aagaacaaaa caaatgaacc aacaaactca ttaatcaaac
     3601 cattgacagt tgctgcatag cgactttctt ttgtaccatg gtcaatactt gaaatagttg
     3661 agaaagttcc caagatgtta tttgggtttt cagttttcaa gtagaatgga cggtatgttg
     3721 ccacaactaa ggcttggcca aagatagccc ccaagacttg cgcgataatg taaggtacca
     3781 cttgtgccca agggaaaaga ccgctaactg caagccctag agtgaaagca gggttgatgt
     3841 gattcccaga tacgttacca aacatcaagg ctgggatcat aacccccata ccataaccaa
     3901 cagcgatgac gatccagcca ctttggtgac ctttcgtacc tttaagttca acgttggcaa
     3961 ctgcaccatt cccaagaatg atcaaaatgg cagttcccaa aaattcagtg gcatacttca
     4021 gtgcccatgt gaaatccatt tgctagattc tccttaaaat tttttagata ttccttattt
     4081 tatcaatttt taccctattt agcaactgat ttctggaaat atttttaaaa aaataggatt
     4141 catagtttcc cagttcaaca gacttgtaag cgtttttatt ctttacgaaa gacctcgttc
     4201 tcaaaaccag gaaaaaagcc cacatctgtg agcttttcct ggttcctaga ttctaaaatc
     4261 tattattttt catcttcttt tttcttgaaa aatcctaatc ctagaccagc taacaaggtc
     4321 atgataccag cactagccaa ggtagcatta gcttctgtac ctgtgtttgg caattcctct
     4381 ctcttacctg tctcataagt cggaacttct gggtctggat tcactggagt ttcagttttt
     4441 ggagtacctg gttctggagt tggtttatct ggtgttggag tctcttgatt tggtagttct
     4501 gggtttggtg tcggaacact tggatgctct ggatttggtt gtgggattgg tttttctggt
     4561 gttgataaac ggtcatacct taccgttatt tctttatcac tagagtctga cgtaacttct
     4621 tgtgattcaa ctgttggaat atctggatct ttgtacttgt caatcttacc agatataacc
     4681 tcgtcccagt ttcctgttgt ccattcaccg taggttacaa ctcccgtgac cttgttctca
     4741 gtttttgtac ggcttaaggt tacaggttga acaacatctt cttttacatt ttggttcgta
     4801 actttatcaa cgtaatgaat gatacgcgtt atagtcttcg tctcagtaga ggttgctgtt
     4861 ttgggaacca ctgtttcctc aacattctca cggtagtaat agtcaactgt tgcaccgtct
     4921 tctggtacgc atttgcagga gttgctacca aggtgtatgt tgttttcctt gtgataactc
     4981 ggtcttcttt gtcctcagtt gttgttttcc cttcaatagt ttttgattct gtggtatact
     5041 cagaacctat cgctaaatca gcttttataa cagactctac caacttctct tgcctacctt
     5101 ctttatagta attggctgtt actgtagcag tggttggcgc ttcgctttct ctataaacta
     5161 aggtcactgt tctaccttcg cttacaatat tcccagttaa acttgcagaa tttgtatctg
     5221 cttctttaaa agtataatat tttccgtcag tagtagtcat gctactgagt tttttatctg
     5281 tgacattata gctggtacca atcagttgtt ttttattggt aatgtaggtt ccgtcacttt
     5341 ctttttctcc aattccagta tcatttttca atgatagcaa acgcccttgt tcatcaacat
     5401 agcgaacttt cacattttct gagattagtt ctgccaattc tgaggttttt ttctttttct
     5461 tgatttcttc ggttattttc cctttctctt cttcgggaat atttagtttt ggaatgattt
     5521 tttcaacaac ggttcgtgat ggttccacag tatcttggat gactgaaaag tcagctagaa
     5581 ttgggagatt atactgaaca cggtgacttt gagtgtttac tcctactctt tcattattct
     5641 ctgaaaatac ttgtacggta taagaaacaa catcttttcc taatagaaca tccccagtag
     5701 agaaatagcc gccttttcct agtttgctat ctccagagcc cacttctttc ctaatcttat
     5761 cagatagttt tttaccagtc agtacattcg ttcgcacaat ccctttgtct acccctacaa
     5821 agtgggagaa ctttttgaac tcttcagaac cagatctagc ccaaccatta ttaagggcat
     5881 ttgcttttgt atttgtattc tctctcaaaa gtttggcgat tagaattata ttcatcggca
     5941 cttagagttg ctgctatatc tgactcttga ataccaactt ccttactacc atttctagcg
     6001 gcagtatatg tgtatttatc tgtttctact tctagctgat tatccttaac atgataggta
     6061 attttctcct ggtataagag tcttcagtag tttatatact ctgtcatcat ctttagcttt
     6121 agaagcagct gagtttagcc aagttggggt attaggagta tctttatcaa cctgtttcaa
     6181 gacattattc aagtcatttg ctagcctatt ggttatcctc actgtgaaag ttttcttcca
     6241 gtctgaacca cttttattag acttagatat gctcatgaaa tcctggtcaa cattcaacac
     6301 aatatcgcct tgttttttag catcttccgt tgcttctgct tcaaattgat catggagttt
     6361 ttgttgctct ggtgtatagt ttttttattt acacgattta atgtactatt ttttatttta
     6421 gtattaagaa ctccattaat acgattttta aactctgctt caaaaaatcc cttaatttgt
     6481 tggtgcgcaa gttcaacatt caaacctttc ttatacaagt cttcattctg atacaagtct
     6541 tcattctgaa cgatttcggc tacacggtga atggtttgat tgtataccgt cttctcttaa
     6601 ccagcagtat ccttagtttt aatgactact cgataggttc ctttagaacc gttatagtca
     6661 tctagtttta aaaaagcatt ccaaacattc aaaaatagtt ggaacttccc ttaatacatc
     6721 cgtcactttc tttttcaaga tagcccaagc ttgctcaata ggattcaaat ccggtgaata
     6781 aggtggtaga ggtaagaaaa agtgtttatc ttggatgcag agttcatcca aaatgttctt
     6841 gggatgaaaa ccagcattgc ccatgacaat aacatgaggt gtcttcaaag caggtaggag
     6901 ttgcgttttg aaccactcca caaagaaatc gcttgtcatg cttttcttgt aaatcatggg
     6961 agctataaac tctccgtcta cttgtcctgc aacaattgaa gttcgctcaa aacgacgtcc
     7021 gctaatcttt tcatagactt tctcccctct aggagcccct gcataaggac gatagagata
     7081 gcggtcgatt cctgtttcat caatataaac aggtgctagg tgctttaaac tattaaaatt
     7141 cttaagaaat aaggctactt ttctgggtct tgttccttaa agctcgtcat ctttttttaa
     7201 agtgacctta atctgcttta aagctgccca tactgaagga acagcacaat caaaatgtgc
     7261 cgcaatttcc cgtaaaaaag catctggatg agcctctaca aaggctttca attcctctaa
     7321 aggaatcttt cggtttttga cgactcgctt tttcctctct atgtgttctt gttcacgtct
     7381 ttcttttccc acgtgaagag agttctgacg ccaacaccaa aaaacttggc tgcctcgaca
     7441 tggctgtgcc cctctttgat gtaatctaat gctcgctgtt taaaatcagt actatatgcc
     7501 atagctttat tataatatgc ttgtttaaaa ctaagtaact atatcaatgt tttgttatga
     7561 gaagacttac tttttttact gaaattgaat ttttcctagc ctcaacatca tataacccca
     7621 aaattcaatc tgacctggtt tgaagagatg ttcgaagcag ataaggtttt actaaaacta
     7681 aaaaaaatga tataattaaa ctgattaaat gttttaaaaa taaaggagaa tttgaatgtc
     7741 ttaccaagaa aattaccaga aatgggttga ttttgtggag cttcctgact accttcgtca
     7801 agatttggaa aatatggacg aaaaaactaa ggaagatgcc ttctatacaa atcttgaatt
     7861 tggtactgca ggtatgcgtg gcttggttgg tgctggtaca aaccgtatca acatctacgt
     7921 tgttcgccaa gctactgaag gattggctcg tttgattgag tcaaaaggtg gaaacgagaa
     7981 agaacgcggt gtagcaattg cctacgatag ccgtcacttc tcacctgagt ttgcctttga
     8041 atctgcggca gttcttgcta aacacggcat caaatcttac gtatttgaaa gccttcgtcc
     8101 gactccagaa ctatcatttg cagttcgtca tctcaactgt ttcgcaggta tcatggtcac
     8161 agccagccac aaccctgctc catttaacgg ttacaaggtt tacggtgaag acggtggaca
     8221 aatgcctcca cacgatgcgg acgctttgac tacttatatc cgtgcaatcg aaaacccatt
     8281 tgcagttgaa gttgctgatg tggaaactga aaaagcttct ggcttgattg aagttatcgg
     8341 cgaagctgtt gacatagaat accttaaaga ggttaaggac ataaacatca acccagcctt
     8401 gattgaagaa tttggtaaag acatgaagat tgtctacaca ccacttcatg gtactggtga
     8461 aatgttggct cgtcgtgctc ttgcccaagc aggatttgac tctgttcaag ttgttgaagc
     8521 gcaagcaact gctgacccag acttttcaac tgtaacatct ccaaacccag aaagccaagc
     8581 agcctttgcc cttgctgaag aacttggtcg tcaagttggt gcagatgttc ttgtcgcaac
     8641 tgacccagac gctgaccgtg ttggtgttga agttcttcaa aaagatggta gctacctcaa
     8701 cctttcaggt aaccaaatcg gtgctatcat ggctaaatac atcttggaag ctcacaaaaa
     8761 cgctggaact cttcctgaaa atgccgctct ctgcaaatct atcgtttcaa ctgacttggt
     8821 aacgaagatt gctgaaagct acggcgcaac tatgttcaac gtcttgacag gtttcaaatt
     8881 tatcgctgaa aaaatccaag aattcgaaga aaaacacaac cacacttaca tgatgggatt
     8941 tgaagaaagc ttcggttact tgattaaacc atttgtacgt gataaagatg ccatccaagc
     9001 cgttcttgta gttgctgaac ttgctgccta ctaccgttct cgtggtttga cacttgctga
     9061 cggtatcgaa gaaatctata aagaatatgg ctactacgca gaaaaaacaa tctctgttac
     9121 tctttcaggt gtcgatggtg ctgaacaaat caaagcgatt atggctaaat tccgcaacaa
     9181 tgctccaaca gaatggaacg caacagctat cactgtcgta gaagacttca aggcacaaac
     9241 tgctactgtt gctgacggta ctgttacaaa cttgacaact cctccaagtg atgtgttgaa
     9301 atacacactt gctgacggtt catggattgc cgttcgccct tcaggtacag aaccaaaaat
     9361 caagttctac attgcagttg taggggaaac caacgaagaa tcacaagcta agattgctaa
     9421 catcgaagca gaaatcaatg catttgtaaa ataaagacct ataaaagatg agaccaacca
     9481 acctcatctt ttttcgtatc aaatctaagc aattttagaa actttatggc atactagact
     9541 tatcaatgaa agcgaggtaa tctcatggaa caatttttag ataacatcaa agaccttgaa
     9601 gtcactacag ttgtgcgtgc gcaagaagct cttgataaaa aagaaactgc aaccttcttt
     9661 atcggtcgca aaacttgccc ttactgccgt aaatttgcag gtacattgtc aggtgtcgta
     9721 gctgaaacca aagctcacat ttacttcatc aatagtgaag aaccaagcca actcaatgat
     9781 ttgcaagcat tccgctcacg ctatggaatc ccaactgtac caggttttgt tcatattaca
     9841 gatggacaaa tcaacgtccg ttgcgactct tcaatgtcag cacaagaaat caaagatttc
     9901 gcaggattgt aaaaaatcag ctaacaagtc ttaaaatcac aaaaacgcat aatgtaaggt
     9961 gcaaaaacct tgatattatg cgttttattg ttcctaaaac agttacatca gtatttcatt
    10021 acagaacatt ttaattttgg aagtcaaatc aatttttaac aatgttttag aaatcacagt
    10081 gggctattcc atattcaatt atccatattc aatcgctatt atcgttttcc tagattacaa
    10141 aaaaaactac gttttgctaa tcaaaacgca gtttcagcca ctattttatc ttactgtcct
    10201 tcttttactt ctttggttgc tacatcttct ccaaaccatt tttggctgat ttcttggaac
    10261 ttgccgtcct tgtaaagact agaaaaagct tcatttatct tcttaaccaa gtttgtatct
    10321 tccttacggg ctccaaccgc aaaagcttct gtttctagtc caactgtaaa gacattataa
    10381 tcgtttaaaa caccttctgc ttctaaataa tagtttgcat agacacggtc aatcaataga
    10441 ccatcaattc gatcgttttt caaatcaatc aaggcttcat taaaggtttg gtattgattc
    10501 gcttccttat tagcgacaat attcttcaaa atttctggat ttgcttcaaa gtccgcataa
    10561 ccagatgaac cagcttgagc tcctaatgtc tttccagtca tatcctttgc agtcgtgata
    10621 ccagatgatt tcttcgtaac caatacctgc tcattcttca tatatgagtt actgaaagcc
    10681 accttttcac ggcgttcgtc tgtagcggaa tagccattcc aaatcagatc aatcgttcct
    10741 tttgtcaatt cagcttcttt caaatcccaa tcaatcggtt gccaatttac cgtgattccg
    10801 tatttttcaa aaacagctgt agctaaatca atatcaaatc ctgcataaga accatctttc
    10861 tgagcaaatc ccattggaac aaaagtacta tcaaatccaa tagtaataga cttgttagac
    10921 tggtactttg accaattatc tccactagtt tcgctagaat ttttcccaca agctactaag
    10981 aacaaagcag tcatcagact gactaataca agcatccatt ttttcatcca tttttcctcc
    11041 tatttaggtt ctactttcaa taatacatct gcgatatttt cagcaaactg caaatcatgg
    11101 gtaaccacaa tctgggtcat cccaagttcc ctattttgca agattagctt ctccacttcc
    11161 aaacgtaatt ctggatccag ggcagaagtt ggttcatcgt agccaatgat ttctgggtca
    11221 atcatcatag cacgcgccaa agccacccgc tgcttttgcc caccagatag tgagaaagga
    11281 taggcctctg cgtgtcctcc tagtcctaac tgttccaaga gtccactcgc cttcttctca
    11341 gcctcttcct gcttcattcc catggtcttc acaggcgata aagtcaaatt ttccagaact
    11401 gatagatgag gaaatagttg aaaatcttgg aagacaaatc ccagtagatt gcgcttctgc
    11461 aattcatcca gctctaaagg ttgtccatta taaaagattt gccctgaatc aatggtttca
    11521 agacctgcaa gcatacgtaa aagagttgtc ttacctccac cagaaggtcc aacgatagcc
    11581 aggatttgct tttcaggaat acttagactg aaattagaca ggatttgttt gtctccaaag
    11641 actttattga tatttcgtaa ttctaacatg gcagcctcct atctataata actatacttc
    11701 ttctcaactt ttttggaaat aattgtcaca atcccaatca aaatcaaata aatggctcct
    11761 gccaagaaca taggaactag actagcatcg cggttagcag ctgttcgact agccaagata
    11821 aggtctgaaa ttccgagagc atagaccaaa gaagtatcct tgaccaaact cataacttca
    11881 ttaaagacac taggaagaac gatcttggtc acttggggca agataatata gcgcactctg
    11941 tcaaaagggc taaacttcaa gaccttggcg gcctcatact gtcctcttgg aatagtgtca
    12001 attcccccac ggaaaatttc tgcaaagtaa gctgcatagt tgagaacaaa ggcaataata
    12061 gctgcaggaa ggcggtctaa acgaatccca atacttggga gcacataata gataaaaatc
    12121 agttgcaaga gtaagggggt tcctcgcata acccagatgt aaatgttaat cagataatgg
    12181 aggggcttcc aatggacttg caaggcaaag gcaatcaaaa cgcccaaggg aatcgaaaat
    12241 agcaagacca gtgcaaagac ctgtacagtc gtgctcgcac cattcagtaa actcggtaat
    12301 atctcaaata aataagacat actgcacctc ctaaaagtaa ttgttcctat tatagcatga
    12361 ataaacaaga ttaccaagta tttttgtaaa aagattctac catatacaaa taaaaaccgt
    12421 agctatcaaa agagataaac tacagttcta tat
//
LOCUS       DAVFER010000057        11951 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1105170250
            SAMEA2167659-rid19724873.denovo.057, whole genome shotgun sequence.
ACCESSION   DAVFER010000057 DAVFER010000000
VERSION     DAVFER010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2167659
            Sequence Read Archive: ERR388902
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11951)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11951)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928716.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928716.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 04:07:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,118
            CDSs (total)                      :: 2,073
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 120
            CDSs (without protein)            :: 120
            Pseudo Genes (ambiguous residues) :: 0 of 120
            Pseudo Genes (frameshifted)       :: 67 of 120
            Pseudo Genes (incomplete)         :: 47 of 120
            Pseudo Genes (internal stop)      :: 34 of 120
            Pseudo Genes (multiple problems)  :: 23 of 120
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11951
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2167659-rid19724873.denovo.057"
                     /strain="1105170250"
                     /db_xref="taxon:1313"
     gene            complement(98..1729)
                     /locus_tag="VU534_001857"
     CDS             complement(98..1729)
                     /locus_tag="VU534_001857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na/Pi cotransporter family protein"
                     /protein_id="HEU1514394.1"
                     /translation="MSINWQEILFHFLGGLGLFLYSIKTMGDGLQQAAGDRLRFYIDK
                     YTSNPFFGVLVGIGMTALIQSSSGVTVITVGLVSAGLLTLRQAIGIVMGANIGTTVTS
                     FLIGFKLGNYALPMLFIGAVCLFFTKNRTVNNIGRILFGVGGIFFALNLMSGAMAPLK
                     DLQVFKDYMIELSKNPVLGVFVGTGLTLLIQASSATIGILQNLYAGNLIDLQGALPVL
                     FGDNIGTTITAIIASLGANIAAKRVAGAHVAFNVIGTVVCVIFLVPFTVLIHWFEATL
                     NLAPEMTIAFAHGTFNITNTIVQFPFIGALAYFVTKIIPGEDEVVKYEPLYLDEHFIK
                     QAPSIALGNAKKELLHLGNYAAKAFDLSYKYIIDLDEKVAEKGHKTEEAINTIDEQLT
                     RYLIALSSEALSQKESEVLTNILDSSRDLERIGDHTEALLNLTDYLQRKNVEFSDAAL
                     KELEEVYRQTSDFIKDALDSVENNDIEKARSLVERHEAINKIERVLRKTHIKRLNKGE
                     CSTQAGVNFIDIISHYTRVSDHAMNLAEKVFAEQI"
     gene            2022..7001
                     /locus_tag="VU534_001858"
     CDS             2022..7001
                     /locus_tag="VU534_001858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000795197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacterial Ig-like domain-containing protein"
                     /protein_id="HEU1514395.1"
                     /translation="MKNPFFERRCRYSIRKLSVGACSLMIGAVLFAGPALAEETAVPE
                     NSGANTELVSGESEHSTNEADKQNEGEHARENKLEKAEGVAIASETASPASNEAATTE
                     TAEAASAAKPEEKASEVVAETPSAEAKPKSDKETEAKPEATNQGDESKPAAEANKTEK
                     EVQPDVPKNTEKTLKPKEIKFNSWEELLKWEPGAREDDAINRGSVVLASRRTGHLVNE
                     KASKEAKVQALSNTNSKAKDHASVGGEEFKAYAFDYWQYLDSMVFWEGLVPTPDVIDA
                     GHRNGVPVYGTLFFNWSNSIADQERFAEALKQDADGSFPIARKLVDMAKYYGYDGYFI
                     NQETTGDLVKPLGEKMRQFMLYSKEYAAKVNHPIKYSWYDAMTYNYGRYHQDGLGEYN
                     YQFMQPEGDKVPADNFFANFNWDKAKNDYTIATANWIGRNPYDVFAGLELQQGGSYKT
                     KVKWNDILDENGKLRLSLGLFAPDTITSLGKTGEDYHKNEDIFFTGYQGDPTGQKPGD
                     KDWYGIANLVADRTPAVGNTFTTSFNTGHGKKWFVDGKVSKDSEWNYRSVSGVLPTWR
                     WWQTSTGEKLRAEYDFTDAYNGGNSLKFSGDVAGKTDQDVRLYSTKLEVTEKTKLRVA
                     HKGGKGSKVYMAFSTTPDYKFDDADAWKELTLSDNWTNEEFDLSSLAGKTIYAVKLFF
                     EHEGAVKDYQFNLGQLTISDNHQEPQSPTSFSVVKQSLKNAQEAEAVVQFKGNKDADF
                     YEVYEKDGDSWKLLTGSSSTTIYLPKVSRSASAQGTTQELKVVAVGKNGVRSEAATTT
                     FDWGMTVKDTSLPKPLAENIVPGATVIDSTFPKTEGGEGIEGMLNGTITSLSDKWSSA
                     QLSGSVDIRLTKPRTVVRWVMDHAGAGGESVNDGLMNTKDFDLYYKDADGEWKLAKEV
                     RGNKAHVTDITLDKPITAQDWRLNVVTSDNGTPWKAIRIYNWKMYEKLDTESVNIPMA
                     KAAARSLGNNKVQVGFADVPAGATITVYDNPNSQTPLATLKSEVGGDLASAPLDLTNQ
                     SGLLYYRTQLPGKEISNVLAVSVPKDDRRIKSVSLETGPKKTSYAEGEDLDLRGGVLR
                     VQYEGGTEDELIRLTHAGVSVSGFDTHHKGEQNLTLQYLGQPVNANLSVTVTGQDEAS
                     PKTILGIEVSQEPKKDYLVGDSLDLSEGRFAVAYSNDTMEEHSFTDEGVEISGYDAQK
                     TGRQTLTLHYQGHEVSFDVLVSPKAALNDEYLKQKLAEVEAAKNKVVYNFASSEVKEA
                     FLKAIEAAEQVLKDHETSTQDQVNDRLNKLTEAHKALNGQEKFTEEKTELDRLTGEVQ
                     ELLAAKPNHPSGSALAPLLEKNKALVEKVDLSPEELTTAKQSLKDLVALLKEDKPAVF
                     SDSKTGVEVHFSNKEKTVIKGLKVERVQASAEEKKYFAGEDAHVFEIEGLDEKGQDVD
                     LSYASIVKIPIEKDKKVKKVFFLPEGKEAVELAFEQTDSHVIFTAPHFTHYAFVYESA
                     EKPQPAKPAPQNTVLPKPTYQPTSDQQKAPKLEVQEEKVAFHRQEHENTEMLVGEQRV
                     IIQGRDGLLRHVFEVDENGQRRLRSTEVIQEAIPEIVEIGTKVKTVPAVVATQEKPAQ
                     NTAVKSEEASKQLPNTGTADANEALIAGLASLGLASLALTLRRKREDKD"
     gene            7091..8287
                     /locus_tag="VU534_001859"
     CDS             7091..8287
                     /locus_tag="VU534_001859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HEU1514396.1"
                     /translation="MAKLTVKDVDLKGKKVLVRVDFNVPLKDGVITNDNRITAALPTI
                     KYIIEQGGRAILFSHLGRVKEEADKAGKSLAPVAADLAAKLGQDVVFPGVTRGAELEA
                     AINALEDGQVLLVENTRYEDVDGKKESKNDPELGKYWASLGDGIFVNDAFGTAHRAHA
                     SNVGISANVEKAVAGFLLENEIAYIQEAVETPERPFVAILGGSKVSDKIGVIENLLEK
                     ADNVLIGGGMTYTFYKAQGIEIGNSLVEEDKLDVAKALLEKANGKLILPVDSKEANAF
                     AGYTEVRDTEGEAVSEGFLGLDIGPKSIAKFDEALTGAKTVVWNGPMGVFENPDFQAG
                     TIGVMDAIVKQPGVKSIIGGGDSAAAAINLGRADKFSWISTGGGASMELLEGKVLPGL
                     AALTEK"
     gene            8423..8950
                     /locus_tag="VU534_001860"
     CDS             8423..8950
                     /locus_tag="VU534_001860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000119911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HEU1514397.1"
                     /translation="MSYFKKYKFDKSQFKLGMRTFKTGIAVFLVLLIFGFFGWKGLQI
                     GALTAVFSLRESFDESVHFGTSRILGNSIGGLYALVFFLLNTFFHEAFWVTLVVVPIC
                     TMLTIMTNVAMNNKAGVIGGVAAMLIITLSIPSGETILYVFVRVLETFMGVFVAIIVN
                     YDIDRIRLFLEKKEK"
     gene            9027..9383
                     /gene="glnR"
                     /locus_tag="VU534_001861"
     CDS             9027..9383
                     /gene="glnR"
                     /locus_tag="VU534_001861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000659547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor GlnR"
                     /protein_id="HEU1514398.1"
                     /translation="MKEKEFRRNMAVFPIGSVMKLTDLSARQIRYYEDQELIKPDRNE
                     GNRRMYSLNDMDRLLEIKDYISEGYNIAAIKKKYAEREAKSKKAVSQTEVRRALHNEL
                     LQQGRFASVQSPFGRG"
     gene            9420..10766
                     /gene="glnA"
                     /locus_tag="VU534_001862"
     CDS             9420..10766
                     /gene="glnA"
                     /locus_tag="VU534_001862"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HEU1514399.1"
                     /translation="MPITAADIRREVKEKNVTFIRLMFSDILGTMKNVEIPATDEQLD
                     KVLSNKVMFDGSSIEGFVRINESDMYLYPDLDTWTVFPWGDENGSVAGLICDVYTTEG
                     EPFAGDPRGNLKRALRHMEEVGFKSFNLGPEPEFFLFKLDENGDPTLEVNDKGGYFDL
                     APTDLADNTRREIVNVLTKMGFEVEASHHEVAVGQHEIDFKYDEVLRACDKIQIFKLV
                     VKTIARKHGLYATFMAKPKFGIAGSGMHCNMSLFDAEGNNAFFDPNDPKGMQLSETAY
                     HFLGGLIKHAYNYTAIMNPTVNSYKRLVPGYEAPVYIAWAGRNRSPLVRVPASRGMGT
                     RLELRSVDPMANPYVAMAVLLEVGLYGIENKIEAPAPIEENIYIMTAEERKEAGITDL
                     PSTLHNALKALTEDEVVKAALGDHIYTSFLEAKRIEWASYATFVSQWEIDNYLDLY"
     gene            complement(10862..10981)
                     /locus_tag="VU534_001863"
     CDS             complement(10862..10981)
                     /locus_tag="VU534_001863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine synthetase"
                     /protein_id="HEU1514400.1"
                     /translation="MPDIVFEIEFFHSDSLIFFYTSDDKSNSQKSQEDFSKNK"
     gene            11469..11951
                     /locus_tag="VU534_001864"
                     /pseudo
     CDS             11469..11951
                     /locus_tag="VU534_001864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000187281.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
BASE COUNT         3841 a         2181 c         2563 g         3366 t
ORIGIN      
        1 tatatatctg cagaatactc tttcagtttc attcatccta gtcttgctta ggaaaaagta
       61 aaaagccatc caattatgat ggatagcttc ttggttctta gatttgttct gcaaaaacct
      121 tttcagcaag gttcatagcg tggtctgata cacgagtgta gtgtgagatg atgtcgataa
      181 agttgacccc agcttgtgtt gaacattcgc ctttgttgag gcgtttgatg tgggtttttc
      241 tgagaacacg ttctatctta ttgattgctt catgacgttc tacaagactg cgtgcttttt
      301 caatatcatt gttttccaca ctatccagag catctttgat aaagtcacta gtttggcggt
      361 aaacttcctc taattctttc aaggcggcat cagaaaattc aacatttttc cgttgaagat
      421 agtcagtcag attgagtaga gcctccgtgt ggtctccaat ccgttccaaa tcacgggagg
      481 aatcaaggat attggtaagc acttcacttt ctttttggct gagagcttcg cttgaaaggg
      541 caatgagata acgtgttaat tgctcatcga tggtgttaat tgcttcttcg gttttatgcc
      601 ctttttcagc aactttttca tccaagtcaa tgatgtactt ataggaaagg tcaaaggctt
      661 tagcagcgta gtttcctaag tgcaagagct ctttcttagc atttcctaga gcgatagatg
      721 gggcctgttt gatgaaatgt tcatcaagat ataagggttc gtatttgaca acctcgtcct
      781 ctccaggaat aatcttggtt acaaagtaag ccagagctcc gataaatgga aattggacaa
      841 tggtgttggt aatattaaag gttccgtgag caaaggcgat ggtcatttcc ggtgctagat
      901 ttagcgtagc ttcaaaccaa tgaatcagga cagtaaaagg aactagaaaa ataacgcaga
      961 caactgttcc gataacgttg aaggcaacat gagctcctgc tacccgttta gctgcaatat
     1021 tagcccctaa agaggcaatg atggctgtaa tggttgtccc gatattgtca ccaaatagaa
     1081 ctggcaaagc tccctgtaga tcaattagat tgccggcgta gaggttttgt aaaatcccaa
     1141 tggtagccga agaagcttga attagcaagg tcaagccagt accgacaaag acacccaaaa
     1201 caggattctt acttagctca atcatatagt ccttaaagac ctgtaaatcc ttgagtggag
     1261 ccattgcgcc gctcatgaga ttgagggcaa aaaagatacc accgacacca aagaggatgc
     1321 gtccgatatt attgactgtc cgatttttcg taaaaaaaag acagacggca ccgataaaga
     1381 gcataggtag ggcatagtta cctaatttaa aaccgatgag aaaggatgtg acagttgtcc
     1441 caatattagc acccatgaca atcccgatag cctgacgtaa ggttaagaga ccggcactga
     1501 ccaggccgac tgtgataact gttacaccag aactagactg aattagagca gtcatcccaa
     1561 taccaaccag aactccaaag aaaggattac tagtatattt gtcaatgtaa aaacgaaggc
     1621 gatctccagc agcttgttgt aaaccgtctc ccatggtctt gatgctatat aagaatagcc
     1681 ccagaccacc taaaaagtga aataaaattt cctgccaatt aatggacatt tctttttcct
     1741 ccgaaaaata atcgcggaat atctcctatt ctattttaaa ggataaaagt aaatctaaca
     1801 agtgttaatg tcaagtttgt aaaagaaaat tataattgat aagtgtatta tttttaagag
     1861 tttttaacct tattttagat ttgtgcaaac agttattgtt ttttgtctaa aaatgtttta
     1921 ggataaaaat gtgattatca tggttctaga gtttgataaa aaactacaga atataaagcg
     1981 ctttcttgaa aacaacaaaa tcaatctttt aggaggagaa aatgaagaat ccattttttg
     2041 aaagacgttg tcgttacagt attcgtaagt tatcagtagg agcctgctcg ctgatgattg
     2101 gtgctgtttt atttgctggt ccagccttgg ctgaagaaac tgcagttcct gaaaatagcg
     2161 gagctaatac agagcttgtt tcaggagaga gtgagcattc gaccaatgaa gctgataagc
     2221 agaatgaagg ggaacatgct agagaaaaca agctagaaaa ggcagaagga gtagcgatag
     2281 catctgaaac tgcttcgcca gcaagcaatg aagctgcaac tactgaaact gcagaagcag
     2341 ctagcgcagc taaaccagag gaaaaagcaa gtgaggtggt tgcagaaaca ccatctgcag
     2401 aagcaaaacc taagtctgac aaggaaacag aagcaaagcc cgaagcaact aaccaagggg
     2461 atgagtctaa accagcagca gaagctaata agactgaaaa agaagtccag ccagatgtcc
     2521 ctaaaaatac agaaaaaaca ttaaaaccaa aggaaatcaa atttaattct tgggaagaat
     2581 tgttaaaatg ggaaccaggt gctcgtgaag atgatgctat taaccgcgga tctgttgtcc
     2641 tcgcttcacg tcggacaggt catttagtca atgaaaaagc tagcaaggaa gcaaaagttc
     2701 aagccttatc aaacaccaat tctaaagcaa aagaccatgc ttctgttggt ggagaagagt
     2761 tcaaggccta tgcttttgac tattggcaat atctagattc aatggtcttc tgggaaggtc
     2821 tcgtaccaac tcctgacgtt attgatgcag gtcaccgtaa cggggttcct gtatacggta
     2881 cactcttctt caactggtct aatagtattg cagatcaaga aagatttgct gaagctttga
     2941 agcaagacgc agatggtagc ttcccaattg cccgtaaatt ggtagacatg gccaagtatt
     3001 atggctatga tggctatttc atcaaccaag aaacaactgg agatttggtt aaacctcttg
     3061 gagaaaagat gcgccagttt atgctctata gcaaggaata tgctgctaag gtaaaccatc
     3121 caatcaagta ttcttggtac gatgccatga cctataacta tggacgttat catcaagatg
     3181 gtttgggaga atacaactac caattcatgc aaccagaagg agataaggtt ccggcagata
     3241 acttctttgc taactttaac tgggataagg ctaaaaatga ttacactatt gcaactgcca
     3301 actggattgg tcgtaatcct tatgatgtat ttgcaggttt ggaattgcaa cagggtggtt
     3361 cctacaagac aaaggttaag tggaatgaca ttttagacga aaatgggaaa ttgcgccttt
     3421 ctcttggttt atttgcccca gataccatta caagtttagg aaaaactggt gaagattatc
     3481 ataaaaatga agatatcttc tttacaggtt atcaaggaga ccctactggc caaaaaccag
     3541 gtgacaaaga ttggtatggt attgctaacc tagttgcgga ccgtacgcca gcggtaggta
     3601 atacttttac tacttctttt aatacaggtc atggtaaaaa atggttcgta gatggtaagg
     3661 tttctaagga ttctgagtgg aattatcgtt cagtatcagg tgttcttcca acatggcgct
     3721 ggtggcagac ttcaacaggg gaaaaacttc gtgcagaata tgattttaca gatgcctata
     3781 atggcggaaa ttcccttaaa ttctctggtg atgtagccgg taagacagat caggatgtga
     3841 gactttattc tactaagtta gaagtaactg agaagaccaa acttcgtgtt gcccacaagg
     3901 gaggaaaagg ttctaaagtt tatatggcat tctctacaac tccagactac aaattcgatg
     3961 atgcagatgc atggaaagag ctaacccttt ctgacaactg gacaaatgaa gaatttgatc
     4021 ttagctcact agcgggtaaa accatctatg cagtcaaact atttttcgag catgaaggtg
     4081 ctgtaaaaga ttatcagttt aacctaggac aattaactat ctcggacaat caccaagagc
     4141 cacaatcgcc gacaagcttt tctgtagtga aacaatctct taaaaatgcc caagaagcgg
     4201 aagcagttgt gcaatttaaa ggcaacaagg atgcagattt ctatgaagtt tatgaaaaag
     4261 atggagacag ctggaaatta ctaactggct catcttctac aactatttat ctaccaaaag
     4321 ttagccgctc agcaagtgct cagggtacaa ctcaagaact gaaggttgta gcagtcggta
     4381 aaaatggagt tcgttcagaa gctgcaacca caacctttga ttggggtatg actgtaaaag
     4441 ataccagcct accaaaacca ctagctgaaa atatcgttcc aggtgcaaca gttattgata
     4501 gtactttccc taagactgaa ggtggagaag gtattgaagg tatgttgaac ggtaccatta
     4561 ctagcttgtc agataaatgg tcttcagctc agttgagtgg tagtgtggat attcgtttga
     4621 ccaagccacg taccgttgtt agatgggtca tggatcatgc aggagctggt ggtgagtctg
     4681 ttaacgatgg cttgatgaac actaaagact ttgaccttta ttataaagat gcagatggtg
     4741 agtggaagct agctaaggaa gtccgtggta acaaagcaca cgtgacagat atcactcttg
     4801 ataaaccaat cactgctcaa gactggcgct tgaatgttgt cacttctgac aatggaactc
     4861 catggaaggc tattcgtatc tataactgga aaatgtatga aaagcttgat actgagagtg
     4921 tcaatattcc gatggccaag gctgcagccc gttctctagg caataacaag gtacaagttg
     4981 gctttgcaga tgtaccggct ggagcaacta ttaccgttta tgataatcca aattctcaaa
     5041 ctccgctcgc aaccttgaag agcgaagttg gaggagacct agcaagtgca ccattggatt
     5101 tgacaaatca atctggtctt ctttattatc gtacccagtt gccaggcaag gaaattagta
     5161 atgtcctagc agtttccgtt ccaaaagatg acagaagaat caagtcagtc agcctagaaa
     5221 caggacctaa gaaaacaagc tacgccgaag gggaggattt ggaccttaga ggtggtgttc
     5281 ttcgagttca gtatgaagga ggaactgagg acgaactcat tcgcctaact cacgcaggtg
     5341 tatcagtatc aggttttgat acgcatcata agggagaaca gaatcttact ctccaatatt
     5401 tgggacaacc ggtaaatgct aatttgtcag tgactgtcac tggccaagac gaagcaagtc
     5461 cgaaaactat tttgggaatt gaagtaagtc aggaaccgaa aaaagattac ctagttggtg
     5521 atagcttaga cttgtctgaa ggacgctttg cagtggctta tagcaatgac accatggaag
     5581 aacattcctt tactgatgag ggagttgaaa tttctggtta cgatgctcaa aagactggtc
     5641 gtcaaacctt gacgcttcat taccaaggcc atgaagttag ctttgatgtt ttggtatctc
     5701 caaaagcagc attgaacgat gagtacctca aacaaaaatt agcagaagtt gaagctgcta
     5761 agaacaaggt ggtctataac tttgcttcat cagaagtaaa agaagccttc ttgaaagcaa
     5821 ttgaagcggc cgaacaagtg ttgaaagacc atgaaactag cacccaagat caagtcaatg
     5881 accgacttaa taaattgaca gaagctcata aagctctgaa tggtcaagag aaatttacgg
     5941 aagaaaagac agagcttgat cgcttaacag gtgaggttca agaactcttg gctgccaaac
     6001 caaaccatcc ttcaggttct gccctagctc cgcttcttga gaaaaacaag gccttggttg
     6061 aaaaagtaga tttgagtcca gaagagctta caacagcgaa acagagtcta aaagatctgg
     6121 ttgctttatt gaaagaagac aagccagcag tcttttctga tagtaaaaca ggtgttgaag
     6181 tacacttctc aaataaagag aagactgtca tcaagggttt gaaagtagag cgtgttcaag
     6241 caagtgctga agagaagaaa tactttgctg gagaagatgc tcatgtcttt gaaatagaag
     6301 gtttggatga aaaaggtcaa gatgttgatc tctcttatgc ttctattgtg aaaatcccaa
     6361 ttgaaaaaga taagaaagtt aagaaagtat ttttcttacc tgaaggcaaa gaggcagtag
     6421 aattggcttt tgaacaaacg gatagtcatg ttatctttac agcacctcac tttactcatt
     6481 atgcctttgt ttatgaatct gctgaaaaac cacaacctgc taaaccagca ccacaaaaca
     6541 cagtccttcc aaaacctact tatcaaccga cttctgatca acaaaaggct cctaaattgg
     6601 aagttcaaga ggaaaaggtt gcctttcatc gtcaagagca tgaaaatact gagatgctag
     6661 ttggggaaca acgagtcatc atacagggac gagatggact gttaagacat gtctttgaag
     6721 ttgatgaaaa cggtcagcgt cgtcttcgtt caacagaagt catccaagaa gcgattccag
     6781 aaattgttga aattggaaca aaagtaaaaa cagtaccagc agtagtagct acacaggaaa
     6841 aaccagctca aaatacagca gttaaatcag aagaagcaag caaacaattg ccaaatacag
     6901 gaacagctga tgctaatgaa gccctaatag caggcttagc cagccttggt cttgctagtt
     6961 tagccttgac cttgagacgg aaaagagaag ataaagatta aatatcgaaa aatcttgtga
     7021 aatctttcct tatatttcca aagtgtgata taatagtttc gaataaaata aataaaggag
     7081 tttttgtaac atggcaaaac ttactgttaa agacgttgac ttgaaaggta aaaaagtcct
     7141 cgttcgtgtt gacttcaacg taccattgaa agatggcgta atcactaacg ataaccgtat
     7201 cacagcagct cttccaacta ttaagtacat catcgaacaa ggtggacgtg caattctttt
     7261 ctctcacctt ggacgtgtga aagaagaagc tgataaagct ggtaaatcac ttgctcctgt
     7321 agcagctgac ttggcagcaa aacttggtca agatgttgtt ttcccaggtg tcactcgtgg
     7381 tgctgaatta gaagcggcaa tcaacgctct tgaagatgga caagttctct tggttgaaaa
     7441 cactcgttac gaagatgttg acggcaagaa agaatctaaa aacgatcctg aacttggtaa
     7501 atactgggca tcacttggag atggtatctt cgtaaacgat gcattcggta cagctcaccg
     7561 tgcacacgca tctaacgttg gtatctcagc aaacgttgaa aaagcagttg ctggtttcct
     7621 tcttgaaaac gaaattgcct acatccaaga agcagttgaa actccagaac gtccattcgt
     7681 ggctatcctt ggtggttcaa aagtttcaga caagatcggt gttatcgaaa acttgcttga
     7741 aaaagctgat aacgtcctta tcggtggtgg gatgacttac acattctaca aagcacaagg
     7801 tatcgaaatc ggtaactcac ttgtagaaga agacaaattg gatgttgcga aagctcttct
     7861 tgaaaaagca aatggtaaat tgatcttgcc agttgactca aaagaagcta acgcatttgc
     7921 tggttacact gaagtgcgtg acactgaagg tgaagcagtt tctgaaggct tccttggtct
     7981 tgacatcggt ccaaaatcta tcgccaaatt tgacgaagct ttgactggtg ccaaaacagt
     8041 cgtatggaac ggacctatgg gtgtatttga aaacccagat ttccaagctg gtacaatcgg
     8101 tgtgatggac gctatcgtga aacaaccagg agttaaatca atcatcggtg gtggtgactc
     8161 agctgccgca gcgattaacc ttggccgtgc agacaagttc tcatggatta gtacgggtgg
     8221 tggagcatca atggaacttc ttgaaggtaa ggttcttcca ggacttgcag ccttgacaga
     8281 aaaataagat tttataaata aatcaaagaa gagagggatg aaagttcctc ttttcttttg
     8341 cttaaaataa aaacgcttcc tctcaactat tactcataaa aatcaccgat ttatgataaa
     8401 atggaaatag aaagttgaga ttatgagtta ttttaaaaaa tataaattcg ataaatccca
     8461 gttcaaactt ggtatgcgaa cctttaaaac aggtattgct gtttttctag ttctcttgat
     8521 ttttggcttt tttggctgga aaggtcttca aattggtgct ttgacagccg tttttagcct
     8581 gagggagagt tttgatgaga gtgttcattt tgggacttcg cgtattctag gaaatagtat
     8641 cggtggactc tatgccttgg tcttcttctt attaaatacc tttttccacg aagccttttg
     8701 ggtgaccttg gtagttgttc caatctgcac catgttaacc attatgacaa atgtagccat
     8761 gaataacaaa gcaggggtta ttggtggtgt agcagctatg ttaatcatta ccctatcaat
     8821 tccaagtggt gagacaattt tgtacgtgtt tgtgcgtgta ttagaaacgt ttatgggagt
     8881 ttttgtcgca attatcgtaa attacgatat tgatcgtatt cgtctctttt tagagaaaaa
     8941 agaaaaataa tgttacattt tataacatta tcaattgacg tttgtctttt tttagactat
     9001 aatagacaga aagaaggaaa ttgtaaatga aggaaaaaga atttcgccga aatatggctg
     9061 tttttcctat cggcagtgtt atgaagttga ccgatctatc ggcgcgtcag attcgttatt
     9121 atgaagatca agagttgatc aagcccgatc gaaacgaagg aaatcgtcgc atgtattcct
     9181 tgaatgacat ggatcgtctg cttgaaatca aagattatat ctctgaaggt tataatatcg
     9241 ctgccattaa gaaaaaatat gctgaacgtg aagcgaaatc caagaaagcg gttagtcaga
     9301 ctgaagtacg tcgtgcactt cacaatgaac tcctccaaca ggggcgtttt gcttcagtac
     9361 agtcaccttt tggtcgcggt taggcaaccg caagtagtca tagattaagg agaaaactta
     9421 tgccaatcac agctgcagat attcgtcgtg aagtcaagga aaaaaatgtt acctttattc
     9481 gtcttatgtt ctcagatatt ttgggaacca tgaaaaacgt cgaaattcct gctacagatg
     9541 aacagttaga taaggtcttg tcgaacaagg ttatgtttga tggatcttct attgaaggtt
     9601 ttgtacgtat caatgagtcg gatatgtact tgtacccgga cttggataca tggacagtct
     9661 tcccttgggg agatgaaaat ggaagtgttg caggtctgat ctgtgatgtc tatacaacag
     9721 aaggtgaacc atttgcgggt gaccctcgtg gtaatttgaa acgagctctt cgtcacatgg
     9781 aagaagttgg attcaaatcc ttcaaccttg gtccagagcc agaattcttc ctatttaagt
     9841 tggatgaaaa tggggaccca acacttgaag tgaatgacaa gggtggctac tttgacttgg
     9901 cacctactga ccttgcggac aacacacgtc gtgagattgt gaatgtcttg accaaaatgg
     9961 gatttgaagt agaagcgagt caccacgagg ttgcggttgg acagcatgag attgacttta
    10021 agtacgatga agttctccgt gcttgtgata agattcaaat ctttaagctt gttgttaaaa
    10081 ccattgctcg caaacacgga ctttacgcaa catttatggc gaagccaaaa tttggtattg
    10141 ctggatcagg tatgcactgt aatatgtcct tgtttgatgc agaaggaaat aacgccttct
    10201 ttgatccaaa tgatccaaaa ggaatgcagt tgtcagaaac agcttaccat ttcctaggcg
    10261 gtttgatcaa gcatgcttac aactatactg ccatcatgaa cccaacagtt aactcataca
    10321 aacgtttggt tccaggttat gaagcgcctg tttacattgc ttgggctggt cgtaaccgtt
    10381 cgccacttgt gcgcgtacct gcttcacgtg gtatgggaac tcgtcttgag ttgcgttcag
    10441 tggatccaat ggcgaaccct tacgttgcta tggctgttct tttggaagtt ggtttgtatg
    10501 gtattgaaaa taaaatcgaa gcaccagctc ctatcgaaga aaatatctac atcatgacag
    10561 cagaagagcg caaggaagct ggtattacag accttccatc aactcttcac aacgctttga
    10621 aagctttgac agaagatgaa gtggttaaag ctgctctcgg agatcacatc tatactagct
    10681 tccttgaagc caaacgaatc gaatgggcaa gttatgcaac cttcgtttca caatgggaaa
    10741 ttgataatta tttagacctt tactaatact aatatagaag aaagattgcc tgtgggtaaa
    10801 cagtcacaca gcagtctaag ccatcaaata cctataaccc ttaaaatagc gatttcggtc
    10861 gctatttatt tttcgaaaaa tcctcttgac tcttttgcga attagattta tcatcagacg
    10921 tgtagaagaa aattaaggag tcactatgga aaaattcaat ttcaaaaaca atatcgggca
    10981 agaaaacaag ttacttcaaa tcgaaatcta caagtttact aacttttgca agcttcaaaa
    11041 ttacacatct gtaaatattt tttcgaaaga tatatttgaa gccatagtaa attgagacta
    11101 gaatagtaca ctacatctgc taaaaatttc tagaaactaa tttaactttc ctaatcgatt
    11161 tgtttacatc ttatttcaat ctactatatt atctcaataa atgatgatgg cgactgtttt
    11221 gtttgtgctt gtcgattttt gaatcctgat cgagcggaag aatatttctg ccgaggttgc
    11281 caaggggaaa atcctgaaga tattgaattt tatgatgaac aattacaggc agaaaaggtg
    11341 gaggatttga atattcgatt ggaagtaaaa aattgaatta tctacaatct catcaacaat
    11401 aaacctattt caaccccatt atctataggc gtatttttac gcctttttat atacttgaag
    11461 cacataagaa acattatggg aagtttgctg atggaagcac tcaagaaatt gatgttcctt
    11521 atgatattcc tgatacttgg gagtgggtga ggataaaatc aatttattgg aattttgggc
    11581 aaaataagcc agagaaatcc tttaggtata tagatacgtc tagtattgat agaaaaaaga
    11641 acataatcaa ctacaaaaat ctacaatatc tttcacctga acaagcgcct tcccgtgcta
    11701 gaaaattagt ttcgcagaat agtgtcttat tttcaacagt tagaccatat ctaaaaaata
    11761 ttgctgtagt tagagaactt aaagagtatt tgatagctag tacagcattt attgttttgg
    11821 atactttact taacgaaaca tatttgaaat attatttatt atcagataat tttatcaatc
    11881 gtgttaataa taaatctact ggaacaagtt atcctgcaat caatgattat aattttaatc
    11941 tattattaat t
//
LOCUS       DAVFER010000058        11204 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1105170250
            SAMEA2167659-rid19724873.denovo.058, whole genome shotgun sequence.
ACCESSION   DAVFER010000058 DAVFER010000000
VERSION     DAVFER010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2167659
            Sequence Read Archive: ERR388902
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11204)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11204)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928716.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928716.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 04:07:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,118
            CDSs (total)                      :: 2,073
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 120
            CDSs (without protein)            :: 120
            Pseudo Genes (ambiguous residues) :: 0 of 120
            Pseudo Genes (frameshifted)       :: 67 of 120
            Pseudo Genes (incomplete)         :: 47 of 120
            Pseudo Genes (internal stop)      :: 34 of 120
            Pseudo Genes (multiple problems)  :: 23 of 120
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11204
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2167659-rid19724873.denovo.058"
                     /strain="1105170250"
                     /db_xref="taxon:1313"
     gene            complement(<1..731)
                     /locus_tag="VU534_001865"
     CDS             complement(<1..731)
                     /locus_tag="VU534_001865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001268160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU1514401.1"
                     /translation="MRYDFGKVYKEIRESKGLTQEEVCGGVLSRTSLSKIESGKTTPK
                     YENMEFLLRQINMSFEEFEYICQLYQPSQRTEIMQTYLNMRSIIGTSDLVNLFQKCQD
                     YLKTHHDLPIEEIRDMLEVVIYLRQHGAGELSDHAEQVVKKLWRKIEKQDTWYESDLK
                     ILNTILFSFPIEYLHLITGKILQRLEVYKNYQHLYDLRIAILLNLSTLYLYNQDKNMC
                     KQICYTLLEDAKNKKSYDRLAICYVR"
     gene            1109..1447
                     /locus_tag="VU534_001866"
     CDS             1109..1447
                     /locus_tag="VU534_001866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000915343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase C39"
                     /protein_id="HEU1514402.1"
                     /translation="MLKKYPCTMQHDQSDCAAAVVSTVLLSYKKELSIMKIREIIGTD
                     MYGTTVSGIVSGLNKLNFTVKAVRVALEDLTPKLTFPAILQVKNDLGQNHFVVLHSIK
                     EKINGTRITK"
     gene            1425..1919
                     /locus_tag="VU534_001867"
     CDS             1425..1919
                     /locus_tag="VU534_001867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1514403.1"
                     /translation="MELVLPNNYVALEQEEMMYLDGGAYLSKSACQGICAALAMSPGT
                     FIALTGAAVLTKKLINYIKVGGLGGWLIGAAAGVLALIFLIKICVDTTIKVLLNRIFK
                     ASKVMKRRIFSLFVLDLMVYIFLGYVLVIQKDVYLFSILIIFSNFSVPFIREKEYELF
                     KNKK"
     gene            2073..2285
                     /locus_tag="VU534_001868"
     CDS             2073..2285
                     /locus_tag="VU534_001868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000973716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1514404.1"
                     /translation="MLIVLISVIVALLYHKITEYVNNRKIDIVIFLSLLISHFIWNYY
                     FLPIEILIAISGANLLLSFLKKLQIK"
     gene            3150..4208
                     /locus_tag="VU534_001869"
     CDS             3150..4208
                     /locus_tag="VU534_001869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1514405.1"
                     /translation="MKDDQKYLLAGLYSLLVAIFYFPLIDSKGIFVSILMAVLLLYLI
                     YFIATVIHIVIIKFIRKKSFKYLVLYPFTYDGSWRFQPINLLYFPEMVRDVIPINLVQ
                     EYCQGQPYGLLKKMLKRIRLSREIALLLATIIVYFFTHRILPLSVFTFMFSYILLFVQ
                     SYLGSNTAWIGNRRLIIDDEFEKILLSKSYVKEISSARYSEYLTCEYKNLTPIILIAI
                     FENLLDSYLLQNQSEVDLDIFYKVLPLLYKEKYTMGFNYFVSLNYLLYKVGFLGIIYD
                     NEALRDLSKQYLNKNISELQDGSFEGGIQDAVASKQIVVINEFIACLNSKCMPSQYDR
                     FFYKDRPYIFSRKSSIKG"
     gene            4523..5500
                     /locus_tag="VU534_001870"
     CDS             4523..5500
                     /locus_tag="VU534_001870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001837003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1514406.1"
                     /translation="MKNKRYFFDTILMILLLISTIFCVSPVFIKLDILGTPSHAILTF
                     VLAIPLFYILSQCLHTLLLLVSSIFCKLRPIYFHFIFVIIIGARKYYRILFHQLMGFS
                     PGVAVFYKESQTTKNLFKFYYFLYFTTLISHYFFFTFVYDKPLLLPLIPFSIIIALVQ
                     KLYRIENQQLFLLKSKVLTILESKKNCEFNLQDYHEIWKLQSKSELPCVALSYISLIK
                     PYLSESVREQIDLLEVKRFKKINHPISLYGMLDVIKLNLYLRHYNEKNKYESMLKKIL
                     EVRPDFVLIEQNIDDSLNSSQPLSLSLAISEIQLLLEVYMGIKHVSIRR"
     gene            5877..6251
                     /locus_tag="VU534_001871"
     CDS             5877..6251
                     /locus_tag="VU534_001871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPH_0224 family bacteriocin-like peptide"
                     /protein_id="HEU1514407.1"
                     /translation="MELVLPNNYVVLEQEEMMYLDGGFSIPRWPVATAINIAFNGVLG
                     GGAISLVRNYIRNYGLRRVTSAIAGAAARYVGVRVANRVAGFALSAINGFAAWMSIGN
                     AITTIWANNDVNRRDPNLNALW"
     gene            6459..7361
                     /locus_tag="VU534_001872"
     CDS             6459..7361
                     /locus_tag="VU534_001872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1514408.1"
                     /translation="MIRKLIIFLLMLPLFVLWLELHLLVSNLQLNLEIPFDFVVSTSL
                     TFFVLILSKIVLDILYALKDLYKKEALITIFPFIFIGRKKVNVRFSPYFSFHRKSLSP
                     DDLRSRIIWSFILEIAIILVFILKIPFAIIMLTTIFFWTIMDINHLVFNKTEFLFNQN
                     KWQKEDSFESDLTKTLKDKIQKSELSYSDLMSLLLYDAMNQSTFLTDSELFEDILKKI
                     EDSHNTLLCTGLVELLLYEISISKNHNWSEKIDKIRIELIKINQLDFFYYTSWLRQNF
                     DFCMNREYHKMKSRKLLLSNKKIV"
     gene            7417..7770
                     /locus_tag="VU534_001873"
     CDS             7417..7770
                     /locus_tag="VU534_001873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate lyase"
                     /protein_id="HEU1514409.1"
                     /translation="MELVLPNNYVVIDEEVMMYLDGGAYLSKRACQGICAALAMSSGT
                     FIALAGAAVLTKKLINYIKFGGLGGWLIGAAAGVLATAAGKIAYCIGYGVLNRGCDIN
                     GNPYPWDGFISATVR"
     gene            7767..8495
                     /locus_tag="VU534_001874"
     CDS             7767..8495
                     /locus_tag="VU534_001874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1514410.1"
                     /translation="MSNVDKIRKIHIIVCWVYIFLSFRAIINDTEYFLLIFLAFIYSI
                     VSLPLYSVKNKIVSICLAINSILLISFPILINKFFPESFLTYTVLISVFITELIIFHL
                     IGKDFDTKLTNEYKKISQFRSKVSQSPWIKYLEISSFILTIFPSILYGTVDNHVLTLI
                     FLIKICVDTTIKFLFIRLFDTSTLMKRRIFFLFALDVIAYLFLGYLLVIQKAGYLFSI
                     LLLFSNFSVPFIKEKEYELFKNSK"
     gene            9630..9869
                     /locus_tag="VU534_001875"
     CDS             9630..9869
                     /locus_tag="VU534_001875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000770310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1514411.1"
                     /translation="MKLLDCILDYQERFNGKTCQVSTNYKYLEIFKVNFCLTDLHHLF
                     DLHKITRDYASQTKPAIQDGVFILEDFRNILCTMM"
     gene            9888..10133
                     /locus_tag="VU534_001876"
     CDS             9888..10133
                     /locus_tag="VU534_001876"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1514412.1"
                     /translation="MSLSAISSISKLASCCIVAKDLSKNTMKLDVIFFEDKNKRSAVL
                     GLRRDKSGVFKPVTLHFTSAKKYAKVRKTDVKEMKWL"
     gene            10422..>11204
                     /locus_tag="VU534_001877"
     CDS             10422..>11204
                     /locus_tag="VU534_001877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1514413.1"
                     /translation="MNKKKMILTSLASVAILGAGFVTSQPTFVRAEESPQVVEKSSLE
                     KKYEEAKAKADTAKKDYETAKKKAEDAQKKYEDDQKRTEEKARKEAEASQKLNDVALV
                     VQNAYKEYREVQNQRSKYKSDAEYQKKLTEVDSKIEKARKEQQDLQNKFNEVRAVVVP
                     EPNALAETKKKAEEAKAEEKVAKRKYDYATLKVALAKKEVEAKELEIEKLQYEISTLE
                     QEVATAQHQVDNLKKLLAGADPDDGTEVIEAKLKKGEAELNAK"
BASE COUNT         3775 a         1433 c         2073 g         3923 t
ORIGIN      
        1 cggacatagc agatagccag cctatcgtag cttttcttat tcttggcgtc ctccagtaaa
       61 gtgtagcaga tttgcttaca catgttttta tcttgattgt atagatagag tgtggaaagg
      121 tttagcagga ttgctattcg caagtcatat aaatgttgat agtttttata gacttctagg
      181 cgttgcaata tttttccagt gatgagatgg aggtattcaa tgggaaaact gaaaagaatg
      241 gtattgagga tttttagatc actctcatac catgtatctt gtttttcaat ttttctccaa
      301 agttttttga caacctgttc tgcgtgatct gatagttccc ctgccccgtg ttgacggaga
      361 taaatgacaa cttcaagcat atctctgatt tcttctatag ggagatcgtg gtgggtcttg
      421 aggtagtctt ggcatttttg aaataaattg acaagatcgc tggtcccgat aatggaacgc
      481 atattgagat aggtttgcat aatctctgtg cgttgacttg gttgataaag ttgacagata
      541 tattcaaact cttcaaaact catattgatt tgacggagaa gaaattccat attttcatat
      601 tttggggttg tcttgccact ttcgattttt gataagctgg ttcttgagag aacaccccca
      661 cagacctctt cttgggtcag cccctttgac tcacgtattt ctttatagac ctttccgaaa
      721 tcataacgca tgattttctc ctttctgtga aaaaagttaa cgtaatttta aaatgagctt
      781 aataagaggt atgatgtagg tagaaaataa agataggaga aaaagtatga ataaaaaaat
      841 attttgtatt ctagtatgta tgatatcatt gattagtctg gccataatct ttccatgggg
      901 ctggtcgata taatgtaagg gagcttgagt tgttaaagga ggcttagtcc ttggacaaaa
      961 atctgctgta ctacaatgct tggaaagata tcaagaacaa agaatgatac gattgaaaat
     1021 aaactgattc aagaactact gggcagtgat tgaggtttgg gtgacatcaa agaaaagtta
     1081 gattaattct aaagaattga gtatttctat gttaaaaaaa tatccttgta cgatgcaaca
     1141 tgatcagtca gattgtgctg cggcagttgt ttcaacagtt cttttatctt acaaaaagga
     1201 actatcaatc atgaagattc gggaaattat tggtacagac atgtatggaa cgactgtcag
     1261 tggtattgtt tcaggtctga ataagttgaa ttttacagta aaagctgttc gagtggcact
     1321 ggaagatttg actccaaaat taacatttcc tgcgattctt caagttaaga atgatttagg
     1381 tcaaaatcat tttgtggtat tacatagtat aaaggagaaa ataaatggaa ctcgtattac
     1441 caaataatta tgttgctctt gagcaagagg agatgatgta tcttgatggg ggggcttatt
     1501 taagcaagag tgcttgtcaa ggaatttgcg cagctttagc tatgagccca ggaactttta
     1561 tagcattgac tggagctgca gttttaacaa aaaaactaat aaactatatt aaggttggag
     1621 gccttggagg ttggcttatt ggtgcagcag caggtgtatt ggctcttatc tttttgataa
     1681 aaatttgtgt agatactacg ataaaggttc tattaaacag aatctttaag gcaagtaagg
     1741 taatgaaaag gaggatattt tctctttttg tactagattt gatggtctat atatttttag
     1801 gttatgtttt agtgatacaa aaagacgtat atctgttttc aattctgata attttttcta
     1861 atttttcagt tccctttatc agagaaaaag agtatgaatt atttaaaaat aagaaatgag
     1921 atagatatgg tagctttatt aaaactgaga ataaagtttg ggagatattt ttatttattt
     1981 taggtgtgtt gttaattgta atttcattac taagtccccc aaaaattaaa ttttggaaat
     2041 agagttagtg agaaggatag gataatagta ttatgttgat tgttttaatt tcagttattg
     2101 ttgcattact gtatcataaa attacagagt atgtcaacaa caggaaaatt gatattgtta
     2161 tttttctatc attgctgatt tctcatttta tttggaatta ctatttttta ccaattgaaa
     2221 tattgatagc aatcagtgga gcaaatttac tattaagttt tttaaaaaaa ttacagatta
     2281 aataatatta ttccatataa catatcaact aggtcattag attttattga agatataaat
     2341 taaaaacgag gttgggaaaa aactcaattt gaaaatgaga ttgagtaaat ctttctatct
     2401 atataacgta tatcatcaat atttttgaac acctgataat atgcattttt cttattttaa
     2461 agattttttg cctttcttca tttcttgaat gaattggaga gatgacttta tttaggtgtt
     2521 tgacattact atagatagga tttagcagta ctaatatgaa ctcatattat aggtgcagac
     2581 ttaaattttg gaagcaagct aaaggatatc ttatctaggt aactaagtgc tataacaaga
     2641 tatattggtg gagttagtat ggcaactatt actaatgctc ttaatattgc ggctactgtt
     2701 gctgaagtct tctcattagg aggagccatt gcatatggtt tagatatcgt agacggtaaa
     2761 tttgatgggt atttatgggc gtaaaactat agctatgaaa catttttttg caggaattgg
     2821 tgaaattcat tttttgttat ttttattata tccaatcact agtccaatta ttggactagt
     2881 gattggatat aataaaataa atctaataaa ttctattatt atagctcttg gtatgatatt
     2941 ggcattaatt ttggtattat caagagtgta tagaaaatat ttttatagag acgatgatga
     3001 ctaaagtttt tatcaataat ttgggctcct tgtcaactgt agtgggttga agaaaagcta
     3061 acgtctgggg aaggggttaa agctttgctt tatcaaatat tgctttatag aaagtcctct
     3121 gtgggattga aaatgataag gtgttttgaa tgaaagatga tcagaaatat ttattagcgg
     3181 gactttattc gcttctagtt gcaatatttt attttccatt gattgattcc aaggggattt
     3241 ttgtaagtat attgatggcg gttttacttt tatatttaat atacttcatt gcaacagtca
     3301 ttcatattgt gataattaag tttataagaa aaaaatcttt taagtatttg gttctatatc
     3361 catttactta tgatgggagc tggagatttc aacctataaa cttactctac tttccagaaa
     3421 tggtgagaga tgtcattccg attaatttag ttcaagaata ttgccaagga caaccttacg
     3481 gactgttaaa aaagatgctg aaaagaattc gattgtcacg agagatagct ttactcctgg
     3541 ctaccattat cgtctatttt tttacgcata gaattctacc tctttcagta tttacgttca
     3601 tgttctctta catattgcta tttgtacaat cttatttggg tagcaatacc gcttggattg
     3661 gaaatagaag attaataata gatgatgaat ttgaaaaaat cttgctttca aaaagttatg
     3721 taaaagaaat atcatctgca cgatactcag aatacttgac atgtgaatac aaaaacctta
     3781 caccaatcat attgatagct atttttgaaa atttgcttga ctcctacttg cttcagaatc
     3841 agagtgaggt tgacttagat attttttata aagttttacc tttgctttat aaagaaaaat
     3901 atactatggg attcaattac tttgtaagtt taaattattt actatataag gttggatttt
     3961 tgggaatcat ttacgataat gaagcattaa gagatttgtc aaaacaatat ttaaacaaaa
     4021 atatttcgga attacaagat ggttctttcg agggcggtat acaagatgct gttgcctcta
     4081 aacaaatagt agttataaat gaatttatag cttgtttaaa ttccaaatgc atgccatccc
     4141 aatatgatag atttttttat aaagatagac cttatatttt ttccagaaag agttctatta
     4201 aggggtgaaa atttgttaca tttggattaa caagtgtcct agggattaga aataactcta
     4261 gtatagctag atatttttga gtaactagaa atatcattag gctactcata tgattgccag
     4321 aaaagatggc tgatgaatct tatttatact gttgcagtag gcgttgtcta ggataaataa
     4381 gctatcttga tgggggagat tggaataatt ttagtagaaa cattaaagga ttatgggcaa
     4441 gtagcacagg attaggtgat gcaatgtgct aagttggctt ggtgttagca gtagtattat
     4501 ttaacaatgg aaagtagact aaatgaaaaa taaacgttat ttttttgaca caattttaat
     4561 gattttacta cttataagca cgatattttg tgtcagccca gtatttataa aattggacat
     4621 cttaggaact ccctctcatg ccatcttaac ctttgtattg gcgataccgt tattctatat
     4681 tttgtctcaa tgcttacata ctttgctatt actagtttcc tcaatctttt gtaaattaag
     4741 accaatttat tttcatttta tatttgtgat cattatagga gctaggaaat actatcgaat
     4801 tctttttcac caactaatgg gatttagtcc aggagtagca gtgttttata aggagagtca
     4861 aacaactaag aatctgttta aattttacta cttcttgtac tttacaacac taatttcaca
     4921 ctattttttc tttacttttg tgtatgacaa accgttgctt ttgcctctta ttccattttc
     4981 tattatcata gcattagtac aaaaacttta tagaattgag aatcagcaat tatttctgtt
     5041 aaaatcaaag gtactaacaa tactggaatc taagaagaat tgtgagttta atcttcagga
     5101 ttatcatgaa atttggaaat tgcaatcaaa atctgagttg ccatgcgtgg ctttatctta
     5161 tatcagtttg atcaagccat atctttcaga gagtgtgcgt gaacaaattg atttattaga
     5221 agttaagcga tttaaaaaaa taaatcatcc aatatcactt tatggtatgt tggatgttat
     5281 aaaattaaat ctatatttac ggcattataa tgaaaaaaat aaatatgaat caatgttaaa
     5341 gaaaatttta gaggtaagac cagactttgt tttaatcgag cagaatattg atgatagttt
     5401 aaatagctcg caaccattat ctttatcttt agccatttca gaaatccaac ttttgcttga
     5461 agtgtatatg gggatcaaac atgtttcaat taggagataa aaccagaata atatttgcca
     5521 ttataggggc aagttgcata ttagtcagta tgtatcttat tccacttatt aaaactgaga
     5581 ataaattttg ggaaatactt ttatttatat taggtgtatt gctaattgga attgcgttat
     5641 taagtcaaaa aaaataaatt ttgaaatagt attagtgagt tcgcaatcat ttattgctag
     5701 tggtttagaa ctgttaagtt tcaaacaata attgatttta aaccttaggt aacctataaa
     5761 aacaaataag gtagagaaag gatatcttat ctaggtagct aagtgataaa aacacagtcg
     5821 tctatcactt gttaggaaac tatcctaact atgcttaata aaaaaggaga aaataaatgg
     5881 aactcgtatt accaaataat tatgttgttc ttgagcaaga agagatgatg tatcttgatg
     5941 ggggattttc tattccgaga tggcctgttg caacagccat taatatagct tttaatggtg
     6001 ttttaggtgg aggagcaatc agtctagtta gaaattatat tcgtaattat ggtttgcggc
     6061 gagttacaag cgcaattgct ggagcagctg caagatatgt tggggtacga gttgcaaata
     6121 gagtggcagg atttgcactg tctgctatta atggatttgc agcttggatg tcaattggca
     6181 atgctattac aacaatctgg gccaataatg atgtaaatag gagagaccca aatttaaacg
     6241 ccttgtggta actagatatg ggtattaaaa tggaaaaaat ttttgttatt attttttttg
     6301 tatgtctatt tatatcatcc ataacttttt tagcctatga ttttgttagc gaagaaataa
     6361 aaaagttgat tatttggatt aatgtcgttt ttttgatttt aatcatagca atgataattt
     6421 atccaaaatt aagaaaatga taaggacact gtaaaattat gatacgtaaa ctaatcattt
     6481 ttttattaat gctccctctt tttgtcttgt ggctagagtt gcatttgtta gtgagtaact
     6541 tgcaattgaa tctagaaatt ccctttgatt ttgtggttag tacgagtctt actttttttg
     6601 ttttgatatt atcaaaaata gttttagaca tactatacgc attgaaagat ttgtacaaga
     6661 aagaagctct tattacgatt tttcctttta tttttatagg caggaagaaa gtaaatgtga
     6721 ggttctcgcc ctatttttca ttccatcgta aaagtttgtc gcctgatgat ttaagatcta
     6781 ggattatatg gagttttatt cttgaaattg ctattatcct agtatttatt ttaaaaattc
     6841 cttttgcaat catcatgctt actacaatat ttttctggac tataatggat atcaatcatc
     6901 tcgtttttaa taagacggaa tttcttttta atcaaaacaa atggcaaaaa gaagattcgt
     6961 ttgaaagtga tttgacgaaa acgttaaagg ataagataca aaaatcagaa ttaagctatt
     7021 ctgacttaat gtcccttctt ctctatgatg cgatgaacca atccaccttt ttaacggata
     7081 gtgaactttt tgaggatatt ttgaaaaaaa tcgaagattc tcataacacc cttctgtgta
     7141 caggtcttgt cgagttactg ctgtatgaaa tttctattag taagaatcat aattggtcag
     7201 aaaagattga taaaattagg atagagctta tcaagattaa tcaattagat tttttctatt
     7261 atacaagttg gttaaggcaa aattttgatt tctgtatgaa tagagagtat cataaaatga
     7321 aatctcggaa attattactg agtaataaaa agatagttta agttcgtcct atttgtaaaa
     7381 caaatgaaac aatttcaact aaggaggaga aaacaaatgg aacttgtatt accaaataat
     7441 tatgttgtga ttgatgaaga agtaatgatg tatcttgatg ggggagctta tttaagcaag
     7501 cgtgcttgtc aaggaatttg cgcagcttta gctatgagtt caggaacttt tatagcatta
     7561 gctggagctg cagttttaac caaaaaacta ataaactata ttaagtttgg aggtcttgga
     7621 ggctggctta ttggtgcagc agcaggtgta ttggctacag cagcaggaaa aatagcttac
     7681 tgtattggat atggtgttct taatagaggt tgtgatatta atgggaaccc ttatccttgg
     7741 gatggattca tatctgcaac agtaagatga gtaatgtaga taagattcga aaaatacaca
     7801 tcatcgtgtg ttgggtgtat atatttttat cattcagggc gattataaat gatacggagt
     7861 attttttgct tattttttta gcttttatct actcaatagt atcactacct ctatattctg
     7921 tgaaaaataa aatagtatct atctgtctag ccataaattc gattctgtta atcagtttcc
     7981 ccattttaat caataagttt ttcccagaaa gttttttgac ttataccgta ttaataagtg
     8041 tttttattac agagttgata atttttcatt taattgggaa agattttgat actaaattga
     8101 ctaacgaata taagaaaatt agtcagttta gaagcaaggt gtctcaatct ccttggataa
     8161 aatatttaga gatttctagt tttatattaa ctatatttcc atctattctt tatggtacag
     8221 ttgataatca tgtactgact cttatctttt tgataaaaat ttgtgtagat actacgataa
     8281 aatttttatt catcagatta tttgacacaa gtactttaat gaagaggaga atattttttc
     8341 ttttcgcatt ggatgttata gcttacttat ttttaggata tcttttagtg attcaaaaag
     8401 caggatatct gttttcgatt ttacttcttt tctctaattt ttcagttcca tttatcaaag
     8461 aaaaggaata cgaattattt aaaaatagca agtaatagaa acataggtta aatcttagaa
     8521 cggcttaaaa tcagatatga taaagggaaa tagtcttatc taggtaacta agtgctacaa
     8581 acacaatcga ggatcacttg ttaggattac attttaatca tgcttaataa gaatggagaa
     8641 ttcctatggg gattgtatta ctctgaagtt tcgaatacct tagttctcgt gattttgagc
     8701 tattctaggt ttagaatcct tcagaatgta aaattttaag cagtcaaaga cttagaatag
     8761 cctgaaaaca tttattttat aacaattcta ggcttagaat tgctcatata tatgtatttg
     8821 agctgctcga tagttaggac agctctattc tgagaaatct gagctatcaa tgcttcagaa
     8881 tagtatttcg ccaatggttt ttattgaaga ggtgattgtg ttatgatagt ctaaaataaa
     8941 attgatttaa tagagtaaat ggagaatcgt tacatgaaac atttttttgc aggaattggt
     9001 gaaataaact ttgtaagtta tttattgtat atatgtgtag gactagcccc tctttttcat
     9061 atatatgtca taggttcgga actgagtttt gtgaaaatag tgttatctat tttgggagtt
     9121 atatttgtaa gtatgttaac tattgctcga atttatcgga cttttctata aagaatagtt
     9181 tggacttgaa ctgtatctaa aaacagaggt tggtagatta tcagcctctt tcttgtcgtt
     9241 gaaaagagtg agatatattg acttttgaaa aaaatgtcat aattgagttg ggataaacct
     9301 aaaagtaata atatagtaga ttgaatctgg aatagtccgt tatgactgtt aaaatatttc
     9361 tagaaattaa tttgactttc ctaatcgatt tgttcacatc ttgtttcaat ctactatact
     9421 ttctcgttaa accgttcggt aattcatggt gacatggaca catagtagta agcacactat
     9481 gtggcttggc agatctaaaa actgttccct tgcgataagc ctaataagca caacataggg
     9541 agttagagaa gccgactcta atcaaccact ttgggcagta gtggtaactg ccccgtgctt
     9601 tttattttga gaaaatatgg agtttgtcgt tgaaattact tgattgtatt ttggattatc
     9661 aagaaagatt caatggaaaa acatgtcaag tatcaacgaa ttataagtat ttagagattt
     9721 tcaaagtgaa tttttgcttg actgatttac atcatttatt tgacttacac aaaatcacac
     9781 gagattatgc tagtcaaaca aaacctgcta ttcaagatgg tgtttttatt ttagaagatt
     9841 ttagaaatat cctatgtaca atgatgtaat cgaaaggata tctttatgtg agtttatcgg
     9901 cgatatcttc tatatctaag ctagcaagtt gttgcatcgt agctaaggat ttatctaaaa
     9961 atactatgaa attggacgtc atattttttg aggataaaaa taaaagatcc gcagttttag
    10021 gtttacgaag agacaaaagc ggagtattta aaccagttac tctacatttt acaagcgcta
    10081 agaaatatgc taaagttcgt aaaacagatg tgaaagaaat gaaatggcta taaagattgt
    10141 ccgcaggctt aagcttgcgt tttttgttgt ttaacgaaat taaaaaacaa gctctctcat
    10201 cggaaatgtt tttataggaa tgaaggaaga tgatgctatg tttaaaaaga gaatcgaaaa
    10261 gggcaaaagt agtatcttta tctatttttt ggagtagaag cttatgatat agaaatttgt
    10321 aataaaaatg taatataaaa catttgacaa atatttacgg ggggagtata cttaatataa
    10381 ttatagtcta aaaatgacta tcagaaaaga ggtaaattta gatgaataag aaaaaaatga
    10441 ttttaacaag tctagccagc gtcgctatct taggggctgg ttttgttacg tctcagccta
    10501 cttttgtaag agcagaagaa tctccacaag ttgtcgaaaa atcttcatta gagaagaaat
    10561 atgaggaagc aaaagcaaaa gctgatactg ccaagaaaga ttacgaaacg gctaaaaaga
    10621 aagcagaaga cgctcagaaa aagtatgaag atgatcagaa gagaactgag gagaaagctc
    10681 gaaaagaagc agaagcatct caaaaattga atgatgtggc gcttgttgtt caaaatgcat
    10741 ataaagagta ccgagaagtt caaaatcaac gtagtaaata taaatctgac gctgaatatc
    10801 agaaaaaatt aacagaggtc gactctaaaa tagagaaggc taggaaagag caacaggact
    10861 tgcaaaataa atttaatgaa gtaagagcag ttgtagttcc tgaaccaaat gcgttggctg
    10921 agactaagaa aaaagcagaa gaagctaaag cagaagaaaa agtagctaag agaaaatatg
    10981 attatgcaac tctaaaggta gcactagcga agaaagaagt agaggctaag gaacttgaaa
    11041 ttgaaaaact tcaatatgaa atttctactt tggaacaaga agttgctact gctcaacatc
    11101 aagtagataa tttgaaaaaa cttcttgctg gtgcggatcc tgatgatggc acagaagtta
    11161 tagaagctaa attaaaaaaa ggagaagctg agctaaacgc taaa
//
LOCUS       DAVFER010000059        11179 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1105170250
            SAMEA2167659-rid19724873.denovo.059, whole genome shotgun sequence.
ACCESSION   DAVFER010000059 DAVFER010000000
VERSION     DAVFER010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2167659
            Sequence Read Archive: ERR388902
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11179)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11179)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928716.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928716.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 04:07:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,118
            CDSs (total)                      :: 2,073
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 120
            CDSs (without protein)            :: 120
            Pseudo Genes (ambiguous residues) :: 0 of 120
            Pseudo Genes (frameshifted)       :: 67 of 120
            Pseudo Genes (incomplete)         :: 47 of 120
            Pseudo Genes (internal stop)      :: 34 of 120
            Pseudo Genes (multiple problems)  :: 23 of 120
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11179
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2167659-rid19724873.denovo.059"
                     /strain="1105170250"
                     /db_xref="taxon:1313"
     gene            <1..845
                     /locus_tag="VU534_001878"
     CDS             <1..845
                     /locus_tag="VU534_001878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HEU1514414.1"
                     /translation="QELMTEFSLDLLLEAIKLARWTYYYHLKQLDKTDKDQELKTEIQ
                     SIFIEHKGNYAYRRVHLELRNRGYLVNHKRVQGLMKVLNLQAKMRKKRKYSSHKGDVG
                     KKAENLIQAQFEGSKTMEKCYTDVTEFAIPASTQKLYLSPVLDGFNSEIIAFNLSCSP
                     NLEQVQTMLEQAFTEKHYENTILHSDQGWQYQHDSYHRFLENKGIQASMSRKGNSQDN
                     GMMESFFGILKSEMFYGYEKTFKSLNQLEQVIIDYIDYYNNKRIKVKLKGLSPVQYRT
                     KSFG"
     gene            complement(970..1173)
                     /locus_tag="VU534_001879"
     CDS             complement(970..1173)
                     /locus_tag="VU534_001879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000594204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU1514415.1"
                     /translation="MIKLYSPYAFLSKYLGAILLSFFCYYAKEIGCNNLTLSVWNDNE
                     GALRFYQRQGMKPQETTMEMIID"
     gene            complement(1166..2248)
                     /locus_tag="VU534_001880"
     CDS             complement(1166..2248)
                     /locus_tag="VU534_001880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HEU1514416.1"
                     /translation="MSKLQQILTYLESEKLDVAVVSDPVTINYLTGFYSDPHERQMFL
                     FVLADQEPLLFVPALEVERASSTVSFPVVGYVDSENPWQKIKHALPQLDFKRVAVEFD
                     NLILTKYHGLKTVFETAEFDNLTPRIQRMRLIKSADEVQKMMVAGLYADKAVHVGFDN
                     ISLDKTETDIIAQIDFAMKREGYEMSFDTMVLTGDNAANPHGIPAANKVENDALLLFD
                     LGVLVNGYASDMTRTVAVGKPDQFKKDIYNLTLEAQQAALDFIKPGVTAHEVDRAARE
                     VIEKAGYGEYFNHRLGHGIGMDVHEFPSIMEGNDMVIEEGMCFSVEPGIYIPGKVGVR
                     IEDCGVVTKDGFNLFTSTSKDLLYFD"
     gene            complement(2374..3156)
                     /locus_tag="VU534_001881"
     CDS             complement(2374..3156)
                     /locus_tag="VU534_001881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase"
                     /protein_id="HEU1514417.1"
                     /translation="MVYTSLSSKDGNYPYQLNIAHLYGNLMNTYGDNGNILMLKYVAE
                     KLGAHVTVDIVSLHDDFDENHYDIAFFGGGQDFEQSIIADDLPAKKESIDNYIQNDGV
                     VLAICGGFQLLGQYYVEASGKRIEGLGVMGHYTLNQTNNRFIGDIKIHNEDFDETYYG
                     FENHQGRTFLSDDQKPLGQVVYGNGNNEEKVGEGVHYKNVFGSYFHGPILSRNANLAY
                     RLVTTALKKKYGQDIQLPAYEDILSQEIAEEYSDVKSKADFS"
     gene            complement(3156..4499)
                     /locus_tag="VU534_001882"
     CDS             complement(3156..4499)
                     /locus_tag="VU534_001882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mur ligase family protein"
                     /protein_id="HEU1514418.1"
                     /translation="MNLKTTLGLLAGRSSHFVLSRLGRGSTLPGKVALQFDKDILQNL
                     AKNYEIVVVTGTNGKTLTTALTVGILKEVYGQVLTNPSGANMITGIATTFLTAKSSKT
                     GKNIAVLEIDEASLSRICDYIQPSLFVITNIFRDQMDRFGEIYTTYNMILDAIRKVPT
                     ATVLLNGDSPLFYKPTIPNPIEYFGFDLEKGPAQLAHYNTEGILCPDCQGILKYEHNT
                     YANLGAYICEGCGCKRPDLDYRLTKLVELTNNRSRFVIDGQEYGIQIGGLYNIYNALA
                     AVAIARFLGADSQLIKQGFDKSRAVFGRQETFHIGDKECTLVLIKNPVGATQAIEMIK
                     LAPYPFSLSVLLNANYADGIDTSWIWDADFEQITDMDIPEINAGGVRHSEIARRLRVT
                     GYPAEKITETSNLEQVLKTIENQDCKHAYILATYTAMLEFRELLASRQIVRKEMN"
     gene            complement(4598..5914)
                     /locus_tag="VU534_001883"
     CDS             complement(4598..5914)
                     /locus_tag="VU534_001883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000958936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-containing oxidoreductase"
                     /protein_id="HEU1514419.1"
                     /translation="MLTYDLIVIGFGKAGKTLAGKLASAGKKVALVERSKAMYGGTCI
                     NIGCIPTKTLLVAAEKDLSFEEVIATKNTITGRLNGKNYATVAGTGVDIFDAEAHFLS
                     NKVIEIQAGDEKKELTAETIVINTGAVSNVLPIPGLATSKNIFDSTGIQSLDKLPEKL
                     GILGGGNIGLEFAGLYNKLGSKVTVLDALDTFLPRAEPSIAALAKQYMEEDGIELLQN
                     IHTTEIKNDGDQVLVVTEDETYRFDALLYATGRKPNVEPLQLENTDIELTERGAIKVD
                     KHCQTNVPGVFAVGDVNGGLQFTYISLDDFRVVYSYLAGDGSYTLEDRLNVPNTMFIT
                     PALSQVGLTESQAADLKLPYAVKEIPVAAMPRGHVNGDLRGAFKAVVNTETKEILGAS
                     IFSEGSQEIINIITVAMDNKIPYTYFTKQIFTHPTLAENLNDLFAI"
     gene            6107..7333
                     /locus_tag="VU534_001884"
     CDS             6107..7333
                     /locus_tag="VU534_001884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000841575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OFA family MFS transporter"
                     /protein_id="HEU1514420.1"
                     /translation="MKSNRYIIAFAGVILHLMLGSTYAWSVYRNPIIEKTGWDQASVA
                     FAFSLAIFCLGLSAAFMGRLVEKFGPKVMGSLSAFLYAGGNILTGFAIDRQELWLLYL
                     AYGILGGLGLGAGYITPVSTIIKWFPDKRGLATGLAIMGFGFASLLTSPIAQHLIAGV
                     GLVETFYILGASYFIIMLLASQFIKRPNEQELAILSSSGKEKTASLTQGMAANQALKS
                     NRFYMLWIIFFINIACGLGLISAASPMAQEMAGLSTSHAAVMVGVLGIFNGFGRLLWA
                     SLSDYIGRPLTFSILLLVNLFFSLSLWLFTDSVLFVVAMSILMTCYGAGFSLIPAYLS
                     DIFGTKELAALHGYILTAWAMAGLAGPILLAETYKMAHSYTQTLFVFLILYSIALALS
                     YYLGRSIKKESQKALT"
     gene            7532..9106
                     /locus_tag="VU534_001885"
                     /pseudo
     CDS             7532..9106
                     /locus_tag="VU534_001885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671067.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
     gene            9370..10158
                     /gene="codY"
                     /locus_tag="VU534_001886"
     CDS             9370..10158
                     /gene="codY"
                     /locus_tag="VU534_001886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HEU1514421.1"
                     /translation="MAHLLEKTRKITSILKRSEEQLQDELPYNAITRQLADIIHCNAC
                     IINSKGRLLGYFMRYKTNTDRVEQFFQTKIFPDDYVQGANMIYETEANLPVEHDMSIF
                     PIESRDDFPDGLTTIAPIHVSGIRLGSLIIWRNDKKFEDEDLVLVEIASTVVGIQLLN
                     FQREEDEKNIRRRTAVTMAVNTLSYSELRAVSAILGELNGNEGKLTASVIADRIGITR
                     SVIVNALRKLESAGIIESRSLGMKGTYLKVLISDIFEEVKKRDY"
     gene            10158..10733
                     /locus_tag="VU534_001887"
     CDS             10158..10733
                     /locus_tag="VU534_001887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HEU1514422.1"
                     /translation="MTKALISIDYTEDFVADSGKLTAGAPAQAISDAISKVTRLAFER
                     GDYIFFTIDAHEENDCFHPESKLFPPHNLIGTSGRNLYGDLGIFYQEHGSDSRVFWMD
                     KRHYSAFSGTDLDIRLRERRVSTVILTGVLTDICVLHTAIDAYNLGYDIEIVKPAVAS
                     IWPENHQFALGHFKNTLGAKLVDENLNELFE"
     gene            10815..10900
                     /locus_tag="VU534_001888"
     tRNA            10815..10900
                     /locus_tag="VU534_001888"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:10849..10851,aa:Leu,seq:aag)
     gene            complement(11023..>11179)
                     /locus_tag="VU534_001889"
     CDS             complement(11023..>11179)
                     /locus_tag="VU534_001889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU1514423.1"
                     /translation="YSNAKLEATNNLIKLIKRNAFGFRNFENFKKRIFIALNIKKERT
                     KFVLSQA"
BASE COUNT         3288 a         2101 c         2452 g         3338 t
ORIGIN      
        1 ttcaagaatt aatgactgag ttttcgttag atcttcttct agaagccatt aaactagctc
       61 gttggaccta ctactatcac ttgaaacagc tagacaaaac agataaagac caagagctta
      121 aaactgaaat tcaatccatc tttatcgaac acaagggaaa ttatgcttat cgccgggttc
      181 atttagaact aagaaatcgt ggttatctgg taaatcataa aagagttcaa ggcttgatga
      241 aagtactcaa tttacaagct aaaatgcgaa agaaacgaaa atattcttct cataaaggag
      301 acgttggtaa gaaggcagag aatctcattc aagcccaatt tgaaggctct aaaacaatgg
      361 aaaagtgcta cacagatgtg actgaatttg ccattccagc aagtactcaa aagctttact
      421 tatcaccagt tttagatggc tttaacagcg aaattattgc ttttaatctt tcttgttcgc
      481 ctaatttaga acaagtacaa accatgttgg aacaggcatt cacagagaag cactacgaga
      541 atacgattct ccatagtgac caaggctggc aataccaaca cgattcttat catcggttcc
      601 tagagaataa gggaattcaa gcatctatgt cacgcaaggg aaacagccaa gacaacggta
      661 tgatggaatc tttctttggc attttaaaat ccgaaatgtt ttatggctat gagaaaacat
      721 ttaaatcact taaccaattg gaacaagtca ttatagacta tattgattac tacaacaaca
      781 aacgaattaa ggtaaaacta aaaggactta gtcctgtgca gtacagaact aaatccttcg
      841 gataaattaa ttgtctaact gtttggggtc agtacacaat acctgatact atgcgtttta
      901 ttgtggggag attttcctca ttttctagtg aaattgaact ttttctaaca tcttttgata
      961 gatgacttct taatcaatta tcatttccat tgttgtttct tggggtttca tcccttgtct
     1021 ttgataaaag cggagagcac cctcgttatc attccagaca cttagggtta gattattgca
     1081 gccaatttct ttagcataat agcagaaaaa tgacaataaa atagccccta gatattttga
     1141 aaggaaagca taggggctat atagtttaat caaaataaag caaatctttg ctggtgcttg
     1201 taaagaggtt gaagccatcc ttggtaacaa caccgcagtc ttcaatacga acaccgactt
     1261 taccagggat atagatacct ggttcaacag agaagcacat gccttcttcg atgaccatgt
     1321 cgtttccttc catgatagat gggaattcat ggacatccat accgatacca tgcccgagac
     1381 ggtggttgaa gtactcacca taaccagctt tttcgatgac ctcacgggca gcgcggtcca
     1441 cttcatgagc agtcacacct ggcttgataa agtcaagagc agcttgttgg gcttcaagag
     1501 tcaagttgta aatatctttc ttgaattggt ctggtttgcc gacagcgact gtacgagtca
     1561 tatctgacgc atagccattg accagaacac ccaggtcaaa gaggagaaga gcatcatttt
     1621 caaccttatt agctgctgga atgccgtgtg gattcgcagc attatcacca gtcaagacca
     1681 tggtatcaaa gctcatttca taaccttcac gtttcatggc aaagtcgatt tgtgcgatga
     1741 tatctgtctc agtcttatca agagaaatat tgtcaaaacc aacatgaaca gccttgtcag
     1801 cataaagacc tgcaaccatc attttttgca cttcatcagc tgatttgatg aggcgcatgc
     1861 gttggatacg aggagtgagg ttgtcaaact cagcagtctc aaaaactgtt ttcaaaccat
     1921 ggtatttggt caagatgaga ttgtcaaact caacagcgac acgtttgaag tcaagttgtg
     1981 gaagagcatg tttgattttt tgccatggat tttcagaatc gacatagccc actactggga
     2041 aggaaacggt gctacttgca cgttctactt caagagctgg gacaaagagg agaggttcct
     2101 gatctgctag gacaaagagg aacatttggc gttcatgggg atcactgtaa aaaccagtga
     2161 ggtaattgat tgtgacgggg tcagatacga cagcgacgtc tagtttttct gattcaagat
     2221 atgttaggat ttgttgtaat ttagacatat gctaccttct ttctacccct ctattttggc
     2281 aaaaaatgag agaaaatgca agggagaagg gtaaaagaaa agacaaaaaa ctccgacaag
     2341 ataacggagt tctttgatat cattttcctt tgtttaagaa aagtcagcct tgcttttgac
     2401 gtcactgtac tcttcagcga tttcttggct gagaatgtcc tcataggcag ggagttggat
     2461 gtcctgacca tatttcttct tgagggcagt agtaactagg cgataagcca gattggcatt
     2521 acgagagagg ataggcccgt ggaagtagga accaaagaca ttcttataat gaaccccttc
     2581 accgaccttt tcttcgttgt ttccatttcc atagacaacc tgtcccagcg gtttttggtc
     2641 atcagagagg aaggtacgac cttggtgatt ttcaaatcca tagtaggttt catcgaaatc
     2701 ttcattgtga atcttgatgt caccgataaa acggttattg gtctggttga gcgtgtagtg
     2761 tcccatgacc cctagccctt cgatacgttt tcctgaagct tcaacataat attgacccaa
     2821 tagttggaaa ccaccgcaga tagccagaac tacaccgtcg ttttggatgt agttgtcaat
     2881 gctctctttt ttagcaggta ggtcgtctgc aatgatactt tgttcaaagt cttgaccacc
     2941 accgaaaaag gcgatgtcgt agtgattttc atcaaagtca tcatggagag aaacgatgtc
     3001 aacggtcaca tgggctccca gtttttcagc cacatacttg agcatgagga tgtttccatt
     3061 gtccccgtag gtattcatga gatttccgta gaggtgggca atgttgagct gataggggta
     3121 attgccatct tttgaggaaa gtgaagtata aaccattagt tcatctcctt tctaacaatc
     3181 tgacgactag ccagcagttc acgaaattcc agcatggcag tataagttgc cagaatatag
     3241 gcatgcttgc agtcttgatt ctcaatggtc ttgagaactt gctccagatt actcgtttca
     3301 gtgattttct cagctggata gccagtcact cggaggcgac gagcgatttc agaatgacga
     3361 acaccgccag cgttgatttc aggaatgtcc atgtcagtga tttgttcaaa gtctgcatcc
     3421 cagatccagc tagtgtcaat tccatctgca tagttggcat taaggaggac agataggcta
     3481 aatggataag gtgctagttt gatcatttcg atagcttggg ttgcaccgac tggattttta
     3541 atcaagacaa gggtacattc cttgtcaccg atatgaaagg tttcttggcg tccaaagaca
     3601 gcacggctct tgtcaaatcc ctgtttgatg agttgcgaat cggcacctag gaaacgggcg
     3661 atggccacag cagctagggc gttatagata ttatagagcc cgccgatttg gataccgtat
     3721 tcttggccgt ctatgacaaa gcgagagcga ttgttggtca actcaaccag ttttgtcaaa
     3781 cgatagtcga gatcaggacg tttacatcca caaccttcac agatataggc acccaagttt
     3841 gcataggtat tatgctcata tttgaggatg ccttggcagt caggacagag aatcccttcg
     3901 gtattgtagt gagccagttg ggctggtccc ttttccaagt caaaaccaaa atactctata
     3961 gggtttggaa tagttggctt gtagaaaagt ggactgtctc cgttaaggag aacagtagca
     4021 gttggaactt tccgaatggc atccaatatc atgttatagg tagtatagat ttcaccgaaa
     4081 cggtccatct ggtcacggaa gatattagta atgacaaaaa gactaggctg gatatagtca
     4141 cagatacgag atagactggc ttcgtcaatt tcgaggacgg caatattttt cccagtttta
     4201 gaagatttgg ctgttaggaa ggttgttgca atccctgtaa tcatgttggc accgcttggg
     4261 ttggttagaa cttgaccata aacctctttt aaaatgccga cagtgagggc agttgtcagg
     4321 gtttttccat ttgttccagt gacaacgaca atctcgtagt tcttagctag gttttgtaaa
     4381 atatctttat caaattgaag ggcgactttc cctgggagcg tacttccacg tccaagacgg
     4441 cttaaaacga agtgggaaga acgcccagca agaaggccca aagtagtttt taagttcatg
     4501 tttctattat atcataaaag aggagaaaga cagatttgag attccgcaga agtaaaaaca
     4561 gcccaaagag ggctgttcga tacgattaaa tctcaactta aatcgcaaac aagtcattca
     4621 agttctcagc caaggttggg tgagtgaaga tttgttttgt gaagtaagtg taaggaatct
     4681 tgttgtccat agcaacagtg atgatgttga tgatttcttg agaaccttct gagaagatgc
     4741 ttgctccaag aatttctttt gtttcagtat tgacaacagc tttgaaggca ccgcgaaggt
     4801 ctccatttac gtgaccacga ggcattgctg caacggggat ttccttaaca gcgtatggaa
     4861 gtttcaaatc agctgcttgg ctttcagtca aaccaacttg tgaaagtgca ggtgtgatga
     4921 acatagtatt tggcacattg agacggtctt caagtgtata gctgccatct ccagcaaggt
     4981 agctgtaaac aacacggaag tcatcaagtg aaatgtaagt aaattgaagg ccaccgttga
     5041 catctccaac tgcaaagaca ccaggaacgt ttgtttgaca gtgtttgtct actttaatag
     5101 caccacgttc agttagttca atatctgtat tttcaagttg aagtggttct acatttggtt
     5161 tgcgtccagt tgcgtagaga agggcgtcga aacggtaagt ttcgtcttca gttacgacaa
     5221 gcacttggtc accatcgttt ttgatttcag tagtatggat attttgaagc aattcaatgc
     5281 catcttcttc catgtattgt ttagcaagag ctgcgatgga aggttctgca cgaggtagga
     5341 atgtatccaa ggcatctagg actgtgacct tgcttccaag tttgttgtaa aggccggcaa
     5401 attcaagacc gatatttccg ccaccaagga ttccaagttt ttcaggtaat ttgtccaagc
     5461 tttggatacc tgttgagtca aagatgtttt tgcttgtagc aagtccaggg attggcaaga
     5521 cgtttgaaac agcaccagtg ttgatgacga ttgtttcagc agtcagttct ttcttttcat
     5581 caccagcttg gatttcgatg actttatttg aaaggaagtg agcttccgca tcaaagatat
     5641 ctacgcctgt accagcaaca gtcgcatagt ttttaccgtt gaggcgacca gtgatcgtgt
     5701 ttttagtagc aatgacttct tcaaaagaca agtccttttc agcagcaact agcaaggttt
     5761 tagttgggat acaaccaatg ttgatacaag ttccaccgta catagccttg ctgcgttcaa
     5821 cgagggcaac ttttttgcca gctgaagcca atttacctgc tagtgtttta ccagctttac
     5881 caaatccaat aacaattaaa tcgtatgtta acatttatct tcctcctatt cgaatttcat
     5941 tctagcacaa gaaaaaaact tttgcacaat tctgctacgg aaaagacaga aaaagataaa
     6001 aacgctttcc agacaaaaaa ctagtaattt tttgacaagc ttgataaact aaaatcctat
     6061 ctatttttat ataagataga ataaatgttc gaaaatagga ggttttatga aatcgaatcg
     6121 ttatattatt gcctttgctg gggtcatttt acacttaatg ctgggttcga cttatgcttg
     6181 gagtgtttat cgtaacccta ttattgaaaa aacgggatgg gatcaggctt ctgttgcctt
     6241 cgcctttagt ctagcaatct tttgtttggg cttatcggct gcatttatgg ggcgtttggt
     6301 agaaaaattt ggtccgaaag tcatgggaag tctatctgct tttctatacg caggtggaaa
     6361 tatcttaaca ggatttgcaa tagaccgtca ggagctgtgg ttgttgtatc tcgcttatgg
     6421 cattttaggt gggcttggtt tgggagcagg ctatattacc cctgtgtcga cgattataaa
     6481 atggtttcct gataaacgtg gtctcgcaac aggtttagcg attatggggt ttggttttgc
     6541 ttctttattg actagtccca tagcgcaaca cctcatcgca ggggtagggc ttgtagaaac
     6601 tttttatatt ttaggagcaa gttactttat tatcatgctc ctagcttcac aattcattaa
     6661 gcgtccaaat gagcaagagc ttgcaatttt atcttcttca gggaaagaaa aaacagcctc
     6721 tttgacgcaa ggaatggctg caaatcaggc tctaaaaagc aatcggtttt atatgctttg
     6781 gattattttc tttatcaaca tagcttgtgg tttaggctta atttcagcgg catcgccaat
     6841 ggcacaggag atggctggct tgtctacaag tcatgcagca gtaatggtgg gtgttttggg
     6901 gattttcaat ggatttggtc gcttgctctg ggcgagtttg tctgactata tcggtcgccc
     6961 tctaaccttt agtatattac tgcttgtcaa tcttttcttt tctctctcac tttggctctt
     7021 tacagattcc gttttatttg tagttgctat gtctattttg atgacttgct atggagctgg
     7081 tttttctttg attccagctt atctcagtga tatttttgga accaaggaat tggccgctct
     7141 gcatggttat attttaacag cttgggcaat ggctggttta gcgggaccta ttttattagc
     7201 agagacttat aaaatggctc attcgtacac acaaaccttg ttcgtttttc tcattttata
     7261 cagtatcgcc ttggctttgt cttattatct aggtcgttca atcaaaaaag aaagtcaaaa
     7321 agcgcttaca tgattttctg tagaaatggg gctatctttt gctctggtct tgtgttatac
     7381 tagataggtt gcaaagaaaa cagtactttt cttttgtgga aaagaagcaa cacgatttta
     7441 tatctagtta tatgaaaata cgtcataaaa agaaaagtat aaactaagcc ctatagggtg
     7501 gcttcgcacc acctttagaa agaagaataa cgtgaaattt aatgaattaa acttgtctgc
     7561 tgatttgcta gcagaaattg aaaaagctgg ttttgtagaa gctagtccta tccaagaaca
     7621 aactattcct ttggcccttg aaggcaagga tgttatcggt caagctcaga ctggtacagg
     7681 aaaaactgca gcctttggct tgcctaccct tgaaaaaatc cgtacagaag aagcgactat
     7741 ccaagccttg gtcatcgctc caactcgtga actagctgtc caaagtcaag aagaactctt
     7801 ccgctttggt cgtagtaagg gagtcaaagt ccgttcagta tatggcggat caagcattga
     7861 aaaacaaatt aaggctctta aatctggtgc ccatattgtg gtgggaactc caggtcgcct
     7921 cttggacttg attaaacgca aggccttgaa attacaagac attgaaaccc ttatccttga
     7981 cgaagcggat gaaatgctta acatgggctt ccttgaagac atcgaagcca ttatttcccg
     8041 tgtacctgag aaccgtcaaa ctttgctttt ctcagcaact atgccagatg ccatcaaacg
     8101 tatcggtgtt cagtttatga aagcccctga acatgtcaag attgcggcta aggaattgac
     8161 aacagaattg gttgaccagt actatatccg tgttaaggaa caagaaaaat ttgacaccat
     8221 gactcgtctc atggatgtgg cacaaccaga actcgctatt gtatttggtc gtaccaaacg
     8281 ccgtgtggat gaattgactc gtggtttgaa aattcgtggc ttccgtgcag aaggaattca
     8341 tggcgaccta gactaaaaca aacgtcttcg tgtccttcgt gactttaaaa atggcaatct
     8401 tgatgttttg gttgcgacag acgttgcagc gcgtggtttg gatatttcag gtgtgaccca
     8461 tgtctacaac tacgatattc cacaagatcc tgagagttat gttcaccgta tcggtcgtac
     8521 aggtcgtgct ggtaagtcag gtcaatctat tacttttgtt gctccaaacg aaatgggtta
     8581 ccttcaaatc attgaaaact tgactaagaa acgcatgaaa ggtctcaaac ctgcaagtgt
     8641 agaagaatcc ttccaatcaa aaaaacaggt agctctcaag aaaatcgaac gtgattttgc
     8701 agatgaaacc attcgtgcca actttgagaa atttggtaag gatgctcgca aattggctgc
     8761 tgagtttact ccagaagaat tggcaatgta tatcttgagt ctgacagtcc aagacccaga
     8821 tagccttcca gaagtggaga ttgcacgtga aaaaccacta ccgtttaaac catcaggtaa
     8881 tggtttcggt ggtaaagcta agggaggtcg tggaggccgt cgtggggacg accgtcgaga
     8941 gcgtgatcgc cgtggcaatg gtcgccgtga tgagttcaaa aaaggaagtc gtggcaacga
     9001 tcgttttgat aaggaaaaac gttaccgtaa ggataataaa aaaccacgca atactttaag
     9061 cgaaaagcaa acaggctttg ttattcgtaa caaaggcgat aaataagaaa aagcggttca
     9121 aaatgaatcg cttttttata taaggagacc gaatgtgaaa agacaaataa aattattata
     9181 ttatctttta taatattatg atacacaaaa ataggcaact tgtcaataga aaaggaacaa
     9241 tttaattaaa aatattctgg tttttaatta aattgtaagt caatgcaagt caataaggaa
     9301 ttttcagata attattgaaa aagagacgtt tttatgttat aatgatagcg attaaattcg
     9361 aggtgaaaaa tggcacattt attagaaaaa actagaaaaa ttacatcaat tttgaaacgc
     9421 tcagaggagc agttgcagga tgagctccct tacaacgcta ttacgcgtca gttagcggat
     9481 attattcatt gcaatgcctg cattatcaat agtaagggac gtctgcttgg ctattttatg
     9541 cgttataaaa caaatacaga tcgcgtagag caattcttcc aaactaagat tttcccagat
     9601 gactacgttc aaggggctaa tatgatttac gaaacagaag caaacttgcc tgttgagcat
     9661 gatatgagta ttttccctat tgagagtaga gatgattttc cagatggctt gacgactatt
     9721 gcaccgattc atgtatcggg gattcgcctt ggttctttga ttatttggcg taatgataaa
     9781 aaattcgaag atgaggactt ggttcttgtt gagattgcca gtaccgttgt tgggattcag
     9841 cttcttaact tccaacgtga agaagatgag aaaaatattc gtcgtcgtac tgctgtcacc
     9901 atggcggtca ataccctttc ttactccgaa ctccgtgctg tttcagcaat tttaggggaa
     9961 ttaaatggaa atgaagggaa gttgactgcg tcagtgattg cagatcgtat cggaatcact
    10021 cgctctgtga ttgtcaatgc tcttcgtaaa cttgagtctg cggggattat tgaaagtcgc
    10081 tcacttggaa tgaagggaac ctatcttaag gtcttgattt cagatatttt tgaagaagtg
    10141 aagaaaagag attactaatg acaaaggctt taatttcgat tgattataca gaagattttg
    10201 ttgctgatag tgggaaacta acagcaggtg ctccagctca ggcgatttcg gatgccatca
    10261 gcaaggtaac tcgattagct tttgaacgag gagattatat cttctttact attgatgctc
    10321 atgaagaaaa cgattgtttc catccggaaa gtaagttatt tcctcctcat aatctgattg
    10381 ggacgagtgg acggaattta tatggagatt tggggatctt ttatcaagag catggttcag
    10441 acagtcgtgt cttttggatg gataaacgcc attactcagc tttttcaggg actgacctag
    10501 atattcgttt gagagagcgt agagtgtcta ccgttatctt aacaggtgtc ttgacggata
    10561 tctgtgtcct acatacagct atagatgcct ataatctagg atatgacatc gagattgtta
    10621 aaccagctgt tgcttccatc tggcctgaaa atcatcaatt tgccctaggt catttcaaaa
    10681 atacactcgg agctaagtta gtagatgaaa atctaaatga actttttgag taacctggtt
    10741 ggtgaaaatg aaaaaatttg aaaaaaagtg ttgacaagca tcccaaaagt tgatatacta
    10801 gtaaagtaat cgacgcgggg atggcggaat tggcagacgc gcaggactaa ggatcctgtg
    10861 accgctttag gtcgtgaggg ttcaagtccc tctctccgca taggaaaaga gctagctaaa
    10921 gctagctctt ttgtatttct ctaaaaaatt agaatccagt caaatgtagt ggagaatcag
    10981 cgaaaatagg ctctttgtca actgtagtgg gttgaagaaa agctaagctt gagaaaggac
    11041 aaatttcgtc ctttcttttt tgatgttcag agcgataaaa atccgttttt tgaagttttc
    11101 aaagtttcga aaaccaaagg cattgcgttt gataagtttg atgagattat tggtcgcttc
    11161 caatttggcg tttgaatag
//
LOCUS       DAVFER010000060        11105 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1105170250
            SAMEA2167659-rid19724873.denovo.060, whole genome shotgun sequence.
ACCESSION   DAVFER010000060 DAVFER010000000
VERSION     DAVFER010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2167659
            Sequence Read Archive: ERR388902
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11105)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11105)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928716.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928716.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 04:07:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,118
            CDSs (total)                      :: 2,073
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 120
            CDSs (without protein)            :: 120
            Pseudo Genes (ambiguous residues) :: 0 of 120
            Pseudo Genes (frameshifted)       :: 67 of 120
            Pseudo Genes (incomplete)         :: 47 of 120
            Pseudo Genes (internal stop)      :: 34 of 120
            Pseudo Genes (multiple problems)  :: 23 of 120
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11105
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2167659-rid19724873.denovo.060"
                     /strain="1105170250"
                     /db_xref="taxon:1313"
     gene            complement(185..257)
                     /locus_tag="VU534_001890"
     tRNA            complement(185..257)
                     /locus_tag="VU534_001890"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(222..224),aa:Lys,seq:ctt)
     gene            complement(522..1793)
                     /locus_tag="VU534_001891"
     CDS             complement(522..1793)
                     /locus_tag="VU534_001891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001113185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HEU1514424.1"
                     /translation="MPDNLALRMRPKTIDQVIGQEHLVGPGKIIRRMVEANRLSSMIL
                     YGPPGIGKTSIASAIAGTTKYAFRTFNATVDSKKRLQEISEEAKFSGGLVLLLDEIHR
                     LDKTKQDFLLPLLESGLVIMIGATTENPFFSVTPAIRSRVQIFELEPLSNQDVKEALQ
                     IALSNPERGFDFPIELDEDALDFIATSTNGDLRSAFNSLDLAVLSTPENDEGIRHITL
                     DIMENSLQRSYITMDKDGDGHYDVLSALQKSIRGSDVDASLHYTARLIEAGDLPSLAR
                     RLTVIAYEDIGLANPEAQIHTVTALDAAQKIGFPEARILIANVVIDLALSPKSNSAYV
                     AMDKALADLKTSGHLPIPRHLRDGHYSGSKELGNAQDYLYPHNYPGNWVKQDYLPEKI
                     RNHHYFQAEDTGKYERALAQRKEAIDRLRKI"
     gene            2091..2306
                     /locus_tag="VU534_001892"
     CDS             2091..2306
                     /locus_tag="VU534_001892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000578034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1514425.1"
                     /translation="MMELPSQEILIFTKQIRHWILSDQVISGKRKLFFREDTPKEILD
                     LYENIKSKLDFAYQEVHSNNGLKKYEK"
     gene            2471..2650
                     /locus_tag="VU534_001893"
     CDS             2471..2650
                     /locus_tag="VU534_001893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1514426.1"
                     /translation="MNLIFEEYQFVKIGDKKYRVRSVPMIHSTPPQSVLDRDTFTIDY
                     TDDELLDKEAVFTTH"
     gene            2787..2966
                     /locus_tag="VU534_001894"
     CDS             2787..2966
                     /locus_tag="VU534_001894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicA family
                     toxin"
                     /protein_id="HEU1514427.1"
                     /translation="MPMTQKEMVKLLTAHGWIKTRGGKGSHIKMEKQGERPITILHGE
                     LNKYTERGIRKQAGL"
     gene            3003..3455
                     /locus_tag="VU534_001895"
     CDS             3003..3455
                     /locus_tag="VU534_001895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000961815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="HEU1514428.1"
                     /translation="MLVTYPALFYYDDTDGTEATYFVHFPDFEYSATQGEGISEALAM
                     GSEWLGITVADLIESDGELPQPSDINSLSLIDNDPFKDDEDFVSTYDLDKSFISMVSV
                     DVSEYLGSQEPIKKTLTIPKWADKLGREMGLNFSQTLTDAIADKKVQA"
     gene            3746..4216
                     /locus_tag="VU534_001896"
     CDS             3746..4216
                     /locus_tag="VU534_001896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000257105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3013 family protein"
                     /protein_id="HEU1514429.1"
                     /translation="MATYGFLDILEEELDKNFPFDFEISWDKRNHAVEVSFLLEAQNA
                     AGVEMVDEDGEVSSDDILFEEAVLFYNPAKSTVNEEDYLTVIPYLPKKGFSREFLAYF
                     ALFLKDTAEVGLDVLMDFLEDPEAEEFVMEWNQEVFEEGKIGLEKGEFYPYPRY"
     gene            4235..5323
                     /locus_tag="VU534_001897"
     CDS             4235..5323
                     /locus_tag="VU534_001897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000719715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-2 protease family protein"
                     /protein_id="HEU1514430.1"
                     /translation="MKKIGTYLVYVLAVVFIMLAFACGTIAFAELGYSAVLAFTFGYA
                     FALLSMYLIFILHELGHAFCGYLTGYRLVAFGLGHFILTKKSGRFHLSRTAILKNVGA
                     QYIGLKEDESDQRIILMLSGGLMVHLGLILLAILFGFLTRSWYFAGTWIFLNLSFFLN
                     NILPVDITDGAKIWELLQHPENTKYAYLVLRHSAQTLLAPQEYDLKDFVQAVPEDARG
                     SFADGVLGMQGEVSILEGKEEVAKQQFQALLERTTTPMMQTVAQLSLLHIALLEGDFE
                     QAEQYASIRQVKSFLSLKLSNLQVIQAWYQLKVKKDVDRTRKALKIARQKMDSSRMLR
                     DEKRYYENWLAELEKEMLEGTEDGTRNF"
     gene            5304..5732
                     /locus_tag="VU534_001898"
     CDS             5304..5732
                     /locus_tag="VU534_001898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEU1514431.1"
                     /translation="MELEISDFTGCKIALFCGDKLLTILRDDKASIPWANMWELPGGG
                     REGDESPFECARREVYEELGIHLDEDCLLWSKIYPSVIFKGKKSVFMVGQLRQEQFDN
                     IIFGDEGQGYQLMNVEEFLSSSQVVPQLQERLKDYLKVSD"
     gene            5868..6818
                     /locus_tag="VU534_001899"
     CDS             5868..6818
                     /locus_tag="VU534_001899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000451122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HEU1514432.1"
                     /translation="METWQELKVTVKREGEELVSNLLIELGAQGVAIEDSMDYVGNVD
                     RFGEIFPEVEQQEEIVVTAYYPDTVDVTVVEADLQARLAELTDFMDLGELKIGTTALA
                     EEDWADNWKKYYEPARITHDLTIVPSWTDYEATAGEMIIKLDPGMAFGTGTHPTTKMS
                     LFALEQVLRGGETVLDVGTGSGVLSIASSLLGAKEIFAYDLDDVAVRVAQENIELNPG
                     MENIHVAAGDLLKGVEIEADVIVANILADILIHLIDDAYRLVKDEGYLIMSGIIKDKL
                     DMVRQSAESAGFFLETHMVQGEWNTCVFKKTKDISGVIGG"
     gene            6820..7563
                     /locus_tag="VU534_001900"
     CDS             6820..7563
                     /locus_tag="VU534_001900"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001188214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HEU1514433.1"
                     /translation="MQQYFVKGSAISPVTIEDKETSKHMFQVMRLKEEDEVTLVFDDG
                     IKRLARVLDMENRQFELVQELNDNVELPVQVTIASGFPKGDKLEFIAQKVTELGASQI
                     WAFPADWSVAKWDGKKLGKKVEKLEKIALGAAEQSKRNIVPSIKLFEKKADFLAQLDQ
                     FDSIIVAYEESAKEGEAAALLQAVTGLETGAKLLFIFGPEGGLSPAEIESFEAKGAVL
                     AGLGPRILRAETAPLYALSALSVLVELEK"
     gene            7574..9370
                     /gene="pepF"
                     /locus_tag="VU534_001901"
     CDS             7574..9370
                     /gene="pepF"
                     /locus_tag="VU534_001901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HEU1514434.1"
                     /translation="MEQKHRSEFPEKELWDLTALYQDREDFLRAIEKAREDINQFSRD
                     YKGNLHTFEDFEKAFAELEQIYIQMSHIGNYGFMPQTTDYSNDEFANIAQAGMEFETD
                     ASVALTFFDDALVAADEEVLDRLGKLPHLTAAIRQAKIKKAHYLGADVEKALTNLGEV
                     FYSPQDIYTKMRAGDFEMADFEAHGKTYKNSFVTYENFYQNHEDAEVREKSFRSFSEG
                     LRKHQNTAAAAYLAQIKSEKLLADMKGYDSVFDYLLAEQEVDRVMFDRQIDLIMKDFA
                     PVAQRYLKHVAKVNGLEKMTFADWKLDLDSALNPEVTIDDAYDLVMKSVEPLGQEYCQ
                     EVARYQEERWVDFAANSGKDSGGYAADPYRVHPYVLMSWTGRLSDVYTLIHEIGHSGQ
                     FIFSDNHQSYFNAHMSTYYVEAPSTFNELLLSDYLENQSNDPRQKRFALAHRLTDTYF
                     HNFITHLLEAAFQRKVYTLIEEGETFGASKLNSIMKEVLTDFWGDAIEIDDDATLTWM
                     RQAHYYMGLYSYTYSAGLVISTAGYLHLKHSETGAEDWLNLLKSGGSKTPLESAMIIG
                     ADISTDKPLRDTIQFLSDTVDQIISYSAELGE"
     gene            9616..10170
                     /locus_tag="VU534_001902"
     CDS             9616..10170
                     /locus_tag="VU534_001902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2785 domain-containing protein"
                     /protein_id="HEU1514435.1"
                     /translation="MYQDLLRKIAEEKPNYNQEEIQWLFDHLGNPSPEIRNVLLNQGL
                     HYLSKEKDTRGFSSQYGWVHAFAHGADLLTEVVCHPDFPKNRVHEVFDILGQLFKRMS
                     IRFTDDEDWRLARVIYEPILQGKLEQEQVASWIKTVDFPIEEREDFYKFSNFRSCLVE
                     VYVQLDQRNSLQDDLKEAIQSFQY"
     gene            10281..10949
                     /locus_tag="VU534_001903"
     CDS             10281..10949
                     /locus_tag="VU534_001903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin"
                     /protein_id="HEU1514436.1"
                     /translation="MKKFVAELIGTFMLVFVGTGAVVFGNGLDGLGHLGIAFAFGLAI
                     VVAAYSIGTVSGAHLNPAVSIAMFVNKRLSSSELVNYILGQVVGAFIASGAVFFLLAN
                     SGMSTASLGENALANGVTVFGGFLFEVIATFLFVLVIMTVTSESKGNGAIAGLVIGLS
                     LMAMILVGLKITGLSVNPARSLAPAVLVGGAALQQVWIFILAPIAGGVLAALVAKNFL
                     GTEE"
BASE COUNT         3212 a         2015 c         2639 g         3239 t
ORIGIN      
        1 attttaggac ataaagatat ctccatgttg attgacgttt atgggcatac cttggaggaa
       61 aaaattagtg aggagtttat ggctgtgaaa agtttgttgt aaaaacacgg caaattgcac
      121 gacaattttt aaaaggaaag caaaaaaagc cctatattat aaggcttttc ctgttgtatt
      181 tatatgcccc ctacagggat cgaacctgtg acccacggat taagagtccg ctgctctgcc
      241 agctgagcta aggaggcaaa gaaaaaagct gtattggtgc cgaaacttca cggtttgtat
      301 tgaacccgcg caattaagca ggtgggcaac tcgctctaac tgaagctgtt tccgtgtgag
      361 acggcctaca tgctgttaga agacttttgt ttccctaata atacaaaaaa tagtcggtca
      421 acacttaagt gtgaagtcgt acaccacagc gtttctatat ttatatgata ccactttttc
      481 aaaaaaaatc aagaggaaag tgcaattttt tgaaaaggat ttcagatttt tcgcaaacgg
      541 tcgatagctt cctttctttg agccaaagcc cgttcatatt taccagtatc ttctgcttgg
      601 aaatagtgat gattacgaat tttttctggc agatagtctt gcttgaccca atttccagga
      661 tagttgtgtg gatagagata gtcttgggca ttccccagtt ccttgcttcc actgtagtgc
      721 ccatcacgca ggtgtcgcgg aataggcaag tgccctgatg ttttgaggtc agcaagtgcc
      781 ttatccatag ctacataggc tgagttggat tttggagaaa gggccaaatc aatcacgaca
      841 ttggcgatga gaatgcgggc ttctgggaac ccaatcttct gggcagcatc cagagcagtc
      901 acggtatgaa tctgggcctc aggattggct aagccgatat cttcataggc gataacagtc
      961 aagcgacgag cgagactagg cagatcccca gcctcaatca agcgggcagt atagtggaga
     1021 ctggcatcca catctgagcc acgaatagac ttttgcaggg cagatagaac atcatagtga
     1081 ccgtctccat ccttgtccat agtgatgtag cttctctgaa gactattttc catgatgtct
     1141 aaggtgatgt ggcgaatgcc ctcgtcattc tcaggggtag agagaacagc taagtccagt
     1201 gagttaaagg cagagcgaag gtctccgttt gtagaggttg cgatgaaatc cagcgcatcc
     1261 tcatctagtt ctattggaaa atcaaaacca cgttcagggt tacttagagc tatctgcagg
     1321 gcctctttga cgtcttggtt agacagaggt tccaactcga aaatttgaac tcggctacga
     1381 atggcaggag tgacagagaa gaaaggattt tcagtcgttg ctccaatcat gatgaccagt
     1441 ccactttcca agagaggcaa gaggaagtct tgcttggtct tatctagtcg atgaatttcg
     1501 tctagtaata ggacgagacc accagaaaat ttagcttctt ccgagatttc ttgcagtcgc
     1561 tttttactat caactgtcgc attgaaagtt cgaaaggcat acttggtcgt tccagcgatg
     1621 gcagaggcaa tactggtttt gccgattcca ggagggccat atagaatcat ggaggacaag
     1681 cggttggctt ccaccatgcg gcggatgatt tttccaggtc cgaccagatg ctcctgaccg
     1741 atgacctggt cgatggtttt agggcgcatg cgaagcgcga gattgtctgg catagcagtc
     1801 ctttctaacg tggatttgag tagaatgact catctactat atcttactat gtccattcta
     1861 gcctattagt tgtgatattt caatggtttt gtaataatca gggagtgaga tagaatcttt
     1921 tttactattt aatttaatga ggagaggtat cagcatgaga gatttgattt tccttaaagc
     1981 tcaaaatagg atagttgagc ctaaagaagt ggaagtgctg acttgagaaa taatattgct
     2041 gaatgtcatt gtatgaacta taatgaaaag agaggtgata agcaatggaa atgatggaac
     2101 taccaagtca ggaaattttg atttttacaa aacaaattcg tcattggatt cttagtgatc
     2161 aagttatttc agggaaaaga aaacttttct tccgggaaga tactccaaaa gagattttag
     2221 atttgtacga aaacattaaa tctaaacttg attttgctta ccaagaagtt cattctaata
     2281 atgggttgaa aaaatatgaa aaatagaata attgatgttt ttgaagtagt aaatcgcctc
     2341 cttgtaataa ctgttgaaaa tcctgatttc gaagacttga gagttaatca tactcaatga
     2401 aaatcaaaga gcaaactagg aaactagccg caggctgtac ttgagtacgg taaggcgacg
     2461 ttgacgtggt ttgaatttga ttttcgaaga gtatcagttt gtaaaaattg gagataaaaa
     2521 atatagagta cgcagtgttc ctatgattca ttcaactccg cctcaatctg tcttagatcg
     2581 agatactttt acaattgact atacagatga tgaattgctc gataaagaag cagtttttac
     2641 tactcattag aaaaataggt atgaataaat tggcttccct tagaaccaca tctaggggct
     2701 tttatgtata atagaataat aagtatcact cctttacaat acgtgtaaca cgtgttataa
     2761 tggtgttgtc aggaggtaaa agcgctatgc ctatgacaca aaaagagatg gttaaactcc
     2821 ttacggccca tggttggata aagactagag gcggtaaagg ctcccatatt aaaatggaaa
     2881 agcaagggga aagacctatc acaatccttc atggtgagct gaataagtac actgaaagag
     2941 ggataagaaa gcaagctggg ttgtaaaatt cagtccctgc tttttgatat ggaggtagtg
     3001 aaatgttagt tacgtatcca gctttatttt attatgacga cacagacgga acagaagcga
     3061 cttattttgt ccatttccca gattttgaat actcagctac acaaggagag gggatttctg
     3121 aggctttggc tatggggtcg gagtggctag ggataactgt tgcagatttg atagagagtg
     3181 atggagagtt acctcagcca tcagatatca atagcttgtc tttaattgat aatgatcctt
     3241 ttaaagatga tgaagatttc gtgtcaacct atgaccttga taaatctttt atttctatgg
     3301 tatctgttga tgtatcagaa tacctaggaa gtcaggaacc cattaaaaag actttgacca
     3361 taccaaaatg ggcagataag ttgggacgag aaatggggct taacttttct cagactttga
     3421 cagacgctat tgcagataag aaagttcaag cctaagatta agcgtggtat cgtggtaata
     3481 gtcaataaaa aagcacgtcc acttgtgcta gttactcgcc tattgatttt atagatttat
     3541 tagccctttc gagggctttt tatattgatt tttatgagaa atgaagaaat cagactttta
     3601 agaaaatcac tgataccaag ggtttaaatg aggtaatatg gtataattag gacataaaat
     3661 aattttgtgg taagatggta gtatctattt tagcatattt ccgagcaatc ggggcgatta
     3721 aagagtcgca tagaaagagg acaaaatggc aacatacgga tttttagata ttttagagga
     3781 agagttggac aagaactttc cctttgactt tgagattagc tgggacaaac gcaaccatgc
     3841 ggtagaagtg agttttctat tggaagcgca aaatgctgca ggtgtggaga tggtggatga
     3901 agacggagag gtttcatcag atgacattct ttttgaggaa gcggtccttt tctacaatcc
     3961 tgccaagtca acagtcaatg aggaagacta tttgactgtt attccttacc tgcctaaaaa
     4021 aggattttcc cgtgaatttt tagcttattt tgcgcttttc cttaaagata ctgctgaggt
     4081 tgggctagat gtcctcatgg actttttgga agacccagaa gcagaggaat ttgtcatgga
     4141 atggaaccaa gaagtctttg aagaaggaaa aattggcttg gaaaagggag aattttatcc
     4201 ttatccaaga tactaggagt tggttggagg tgttatgaag aaaattggga cttatttggt
     4261 ttatgtgcta gctgttgtct ttattatgct agcttttgct tgtggaacaa tcgcatttgc
     4321 agagttgggg tattccgcag ttttagcctt tacttttggt tatgccttcg ctcttctaag
     4381 catgtattta atctttattc ttcatgagct gggtcatgct ttttgtggct acttgacagg
     4441 ctatcggctg gtggcttttg gattaggaca ttttattttg accaaaaagt caggcaggtt
     4501 tcatcttagt agaacagcca ttctgaaaaa tgttggtgct caatacattg gtttaaaaga
     4561 ggatgaaagc gatcaaagaa tcatcctgat gctttcagga ggcttgatgg ttcatctcgg
     4621 cttgatatta ttggcgatat tgtttggatt tttgacaaga agctggtatt ttgcagggac
     4681 ttggattttt cttaatttat ctttcttcct aaataacatt ttgccagtcg acatcaccga
     4741 tggagcaaaa atttgggaat tactacaaca ccctgaaaat accaaatacg cctacctggt
     4801 attgagacat tctgcccaga ccttgctagc tcctcaagaa tatgatttga aagactttgt
     4861 tcaagcagtt cctgaggatg cacgagggag ttttgcggat ggtgtattag gtatgcaagg
     4921 tgaagtttcc attttggaag ggaaggaaga agtagctaaa cagcagtttc aagcattact
     4981 tgagaggaca actactccga tgatgcagac agttgcccaa ctatccctgc ttcatatcgc
     5041 cttgttggaa ggagattttg agcaagcgga gcaatatgct agtattcgac aggtcaaatc
     5101 gtttctgtct ctcaaactgt ccaatcttca agtgatacaa gcctggtatc aattaaaggt
     5161 gaagaaagat gtagatcgaa ctcgtaaggc tctcaagatt gctagacaga aaatggatag
     5221 tagtcgaatg ttgagggatg agaaaagata ttatgaaaac tggttagccg agctggaaaa
     5281 ggaaatgtta gaaggaactg aagatggaac tagaaatttc tgatttcaca ggttgcaaga
     5341 ttgctttgtt ttgtggggat aagcttttga ctatcttacg cgatgataag gcaagtattc
     5401 cctgggccaa tatgtgggaa ctgccaggtg gtggccgtga aggggacgaa agcccttttg
     5461 aatgcgctcg gcgtgaagtt tatgaggaac tgggaattca tttagatgaa gactgtctgc
     5521 tttggagcaa gatttatcct agcgtaattt ttaaaggcaa gaaatcggtc tttatggttg
     5581 gtcagctaag acaagaacaa tttgacaata tcatcttcgg agatgaagga cagggctatc
     5641 agctgatgaa tgttgaggaa tttcttagtt ccagtcaagt tgtgcctcag ttgcaagaga
     5701 gattaaaaga ttatttaaaa gtaagtgatt agaaaggatg gttcagttac atttctaaac
     5761 tgaacccgcc ctaaacactg tgccaaaaag ataaacttct cttagacaca agcgtcttca
     5821 gagaatttcc tattttggtt ttgtgtttta cgggcttggt attaataatg gaaacatggc
     5881 aagagttaaa agttacagtg aagcgtgagg gagaggagtt ggtttccaat ctcttgattg
     5941 agctgggagc gcaaggagtc gcaatcgaag acagtatgga ctatgtggga aatgtggacc
     6001 gctttggaga gattttccca gaggtggagc agcaagaaga aatcgtagtg acagcctact
     6061 accctgacac ggtggatgtg acagtggttg aggcggattt gcaggctcgt ctagcagaat
     6121 tgacagattt tatggatttg ggagagttaa aaataggtac gactgccttg gctgaggaag
     6181 actgggcaga caactggaag aaatactatg aacctgctcg tatcactcat gatttgacca
     6241 tcgttccctc ttggacagac tatgaggcga ctgcggggga aatgattatc aagctggatc
     6301 ctggcatggc ttttggtact ggaacccacc caactaccaa gatgagcctt tttgccttgg
     6361 aacaggttct tcgtggtggc gaaacggtgc tagatgtggg gactggttca ggggttctct
     6421 ctattgccag ctcgcttctg ggggctaaag aaattttcgc ctatgacctg gatgatgtgg
     6481 cggttcgtgt ggctcaggaa aatattgagc tcaaccctgg catggaaaat atccatgtag
     6541 cggctggaga tttgcttaag ggtgtggaaa ttgaggcaga tgtgattgtg gctaatatct
     6601 tggcggatat cctcattcat ctaatagacg atgcttatcg cttggtaaag gatgaaggct
     6661 acctgatcat gagtggcatt atcaaggaca agttggacat ggtgcgccag tcggctgagt
     6721 cagctggatt tttcctcgaa actcacatgg ttcaagggga atggaatacc tgtgtcttta
     6781 agaaaaccaa ggatatctct ggtgtgattg gaggctagca tgcagcagta ttttgtaaaa
     6841 ggcagtgcta tctctcctgt cactatcgag gacaaggaaa ccagtaagca tatgtttcag
     6901 gttatgcgct tgaaagaaga ggatgaggtt accttagtct ttgatgatgg catcaagcgc
     6961 ttggcgcgcg tgctggatat ggaaaatcgt cagtttgagt tggtccaaga attaaatgac
     7021 aatgtggaac taccagtcca agtgaccatc gcatctggat ttcccaaggg agacaagctg
     7081 gagttcatcg ctcaaaaagt aaccgaactg ggggctagcc aaatctgggc ctttcctgca
     7141 gactggtcag ttgccaagtg ggatggcaag aaattgggta aaaaagttga aaaactagaa
     7201 aaaattgccc ttggagcagc cgagcaaagc aagcgtaata ttgtaccaag tattaaactt
     7261 ttcgagaaaa aagcagattt tctagctcag ctggaccagt ttgactctat catagtagcc
     7321 tatgaagaat cagctaaaga aggagaagcc gctgcgcttc tgcaagcagt cactggtctt
     7381 gaaacaggag ccaaactgct ctttatcttt ggtccagaag gcggtctctc acctgcagaa
     7441 atcgaaagtt ttgaagctaa aggagccgtt ttggcaggcc taggtcctcg tattttgcga
     7501 gcagaaacag caccgcttta cgctttatca gcccttagtg ttttagtaga attagagaaa
     7561 taagaggaag aaaatggaac aaaaacaccg ttcagaattt ccagagaagg aactctggga
     7621 cttaacagcc ctataccaag accgtgagga tttcttgcgt gcaatcgaga aagctcgcga
     7681 agacatcaac cagtttagcc gtgattacaa gggcaatctt cacacttttg aggatttcga
     7741 gaaggccttt gcggaattgg aacagatcta cattcagatg agccatattg gcaactatgg
     7801 ttttatgcct cagacgacgg actatagcaa tgacgaattt gccaatattg cccaagctgg
     7861 gatggaattt gaaacagatg ccagcgtagc cttgaccttc tttgacgatg ccttggtggc
     7921 agcagatgag gaagtcttgg accgtttggg taaattgcca catttaacag ctgccattcg
     7981 tcaggctaaa atcaaaaaag cccactactt aggggcagat gtggagaagg ccttgacaaa
     8041 tctcggtgaa gttttctaca gtccgcagga catttatact aagatgcgag ctggggattt
     8101 tgaaatggct gactttgaag cccatggcaa gacctacaaa aacagctttg tgacctatga
     8161 gaatttctac caaaaccatg aggatgctga ggttcgtgag aaatccttcc gttccttctc
     8221 agagggactt cgtaagcacc aaaatacggc tgcagcagcc tatctggctc agatcaagtc
     8281 tgaaaaactc ttggctgata tgaagggata cgactctgtc tttgactatc ttctagctga
     8341 acaagaagtg gaccgtgtca tgtttgaccg ccagattgac ctcatcatga aggactttgc
     8401 accagtcgct cagagatacc tcaagcatgt tgccaaggta aatggtcttg aaaagatgac
     8461 ctttgcagac tggaaattgg acttggacag cgccctgaat cctgaagtga ctattgacga
     8521 tgcctatgat ttggtcatga agtcggtaga acctttgggg caagaatatt gtcaggaagt
     8581 tgctcgttac caagaagagc gctgggtgga ctttgctgct aacagtggca aggattccgg
     8641 tggttatgcg gcggacccat atcgcgtaca cccttatgta ctcatgagct ggacaggccg
     8701 tttgagcgat gtctatacct tgattcatga aatcgggcat tctggtcaat tcatcttttc
     8761 agacaatcat caaagttact tcaatgccca tatgtcgacc tactatgttg aagcaccgtc
     8821 aaccttcaat gaattgctac tcagtgatta cttggagaac cagtctaatg acccacgtca
     8881 aaaacgcttc gctctggctc atcgcttgac agacacctac ttccataact ttatcaccca
     8941 cctcttggaa gccgccttcc agcgtaaggt gtatacattg attgaagaag gggagacctt
     9001 tggagcaagc aagctcaaca gcattatgaa ggaagttttg acggatttct ggggagatgc
     9061 tattgaaatt gacgatgatg caactctgac ttggatgcgc caagctcact actatatggg
     9121 cttgtatagt tacacttact cagcaggact agttatctcg actgctggtt accttcatct
     9181 aaaacattct gaaactggag ctgaagactg gctcaatctc ctcaaatcag gtggtagcaa
     9241 gacaccactt gagtcagcca tgattatcgg tgctgatatt tcaacagaca aaccactccg
     9301 tgataccatc caattcttgt ctgacacagt tgaccagatt atctcctata gtgctgagtt
     9361 gggagagtag gggaatagaa aaatttttta gaatgatgtt tatgggcttg ttaagcgtca
     9421 ttctatttgt cttagttgta gctattttca aaaatgtcgt tgaaggtcgt gatgttaaat
     9481 ttgaacttac tgtagaactg gtattgatag ttatttacgt cattttatat cagattgtat
     9541 ttaattgaga attcaatatt gagtcattta agactgcctt tttgaacagt tgctagaaat
     9601 gtagaggtat tgaccatgta tcaagattta ctaagaaaaa tagcagaaga aaaaccaaat
     9661 tataaccagg aagaaatcca gtggttgttt gatcatttgg gaaatccttc tccagaaatt
     9721 cgtaatgtcc ttttaaatca aggcttgcac tatctttcaa aagaaaagga tacaaggggt
     9781 ttctcaagtc agtatggttg ggttcacgct tttgcacatg gagccgattt actgacagag
     9841 gtggtttgtc atccagactt tcctaaaaac agagttcatg aagtatttga tatacttggc
     9901 caactattta aaagaatgtc gattcgcttt acagatgatg aggattggcg tttagcaaga
     9961 gtgatctatg aacctatttt acaagggaag ttggagcaag aacaagtagc ttcttggata
    10021 aaaactgttg attttccgat agaagaaagg gaggattttt acaaattttc caactttaga
    10081 tcctgtctgg tggaagtcta tgtccaactt gaccagagaa atagtttaca agatgacctg
    10141 aaagaagcta tccagtcttt tcaatactag ggattagcta atagttctat gattttcaaa
    10201 aaatttccaa tcaattttct tgaaaccctt tcctactttt gatagactag tatctagttt
    10261 ttgaaaaaag gagaaagaaa atgaaaaaat ttgttgctga gttaatcggt acgttcatgc
    10321 ttgtattcgt cgggacagga gctgttgttt ttggaaatgg tcttgatggc cttggtcacc
    10381 ttggaatcgc ctttgccttt ggtttggcaa tcgtggtggc agcctactca atcggaactg
    10441 tttcaggtgc tcacttgaac ccggctgttt cgattgctat gtttgtaaac aaacgtttgt
    10501 catcttcaga acttgtaaac tacatccttg gtcaggttgt tggagctttc atcgcttctg
    10561 gcgctgtctt cttcctcttg gctaactcag gtatgtcaac tgctagtctt ggtgaaaatg
    10621 ccttggcaaa cggtgtcact gtctttggtg gtttcttgtt tgaagtcatc gcaactttct
    10681 tgtttgtatt ggttatcatg actgtgactt cagaaagcaa gggcaatggc gcgattgctg
    10741 gtttggtaat cggtttgtca ttgatggcga tgattcttgt cggattgaag attactggac
    10801 tttcagtaaa cccagctcgt agcttggcac cagctgtctt ggtaggcggc gcagcccttc
    10861 aacaagtttg gattttcatc cttgcaccaa tcgctggtgg agttcttgca gcccttgttg
    10921 caaaaaattt ccttggaaca gaagaataat tgaaactcaa aaagccttgc tcctcatctt
    10981 gaggaacagg gctttttcgt atgatactct tcgaaaatct cttcaaacca cgtcagcttc
    11041 atcttgccgt aggtatggtt actgacttcg tcagttctat ccacaacctc aaaacagtgt
    11101 tttga
//
LOCUS       DAVFER010000061        10847 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1105170250
            SAMEA2167659-rid19724873.denovo.061, whole genome shotgun sequence.
ACCESSION   DAVFER010000061 DAVFER010000000
VERSION     DAVFER010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2167659
            Sequence Read Archive: ERR388902
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10847)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10847)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928716.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928716.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 04:07:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,118
            CDSs (total)                      :: 2,073
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 120
            CDSs (without protein)            :: 120
            Pseudo Genes (ambiguous residues) :: 0 of 120
            Pseudo Genes (frameshifted)       :: 67 of 120
            Pseudo Genes (incomplete)         :: 47 of 120
            Pseudo Genes (internal stop)      :: 34 of 120
            Pseudo Genes (multiple problems)  :: 23 of 120
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10847
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2167659-rid19724873.denovo.061"
                     /strain="1105170250"
                     /db_xref="taxon:1313"
     gene            complement(208..1632)
                     /locus_tag="VU534_001904"
     CDS             complement(208..1632)
                     /locus_tag="VU534_001904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent glyceraldehyde-3-phosphate
                     dehydrogenase"
                     /protein_id="HEU1514437.1"
                     /translation="MTRYQNLVNGKWKSSEQEITIYSPINQEELGTVPAMTQTEADEA
                     MQAARAALPAWRALSAVERAAYLHKTAAILERDKEEIGTILAKEVAKGIKAAIGEVVR
                     TADLIRYAAEEGLRITGQAMEGGGFEATSKNKLAVVRREPVGIVLAIAPFNYPVNLSA
                     SKIAPALIAGNVVMFKPPTQGSISGLLLAKAFEEAGIPAGVFNTITGRGSEIGDYIIE
                     HKEVNFINFTGSTPIGERIGRLAGMRPIMLELGGKDAALVLEDADLEHAAKQIVAGAF
                     SYSGQRCTAIKRVIVLESVADKLATLLQEEVSKLTVGDPFDNADITPVIDNASADFIW
                     GLIEDAQEKEAQALTPIKREGNLLWPVLFDQVTKDMKVAWEEPFGPVLPIIRVASVEE
                     AIAFANESEFGLQSSVFTNDFKKAFEIAEKLEVGTVHINNKTQRGPDNFPFLGVKGSG
                     AGVQGIKYSIEAMTNVKSIVFDVK"
     gene            complement(2177..4456)
                     /gene="pulA"
                     /locus_tag="VU534_001905"
     CDS             complement(2177..4456)
                     /gene="pulA"
                     /locus_tag="VU534_001905"
                     /EC_number="3.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000283081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pullulanase"
                     /protein_id="HEU1514438.1"
                     /translation="MYNYPMRIHYHRKNGEYDTCSFVKSQDQRIDLLTYKEDYFGALF
                     SFEHPSSHVIESLNFVVHTGQTSKEYSIRFNHYPLLTEVWILEGDDRIYYSENPAIAS
                     PFYKNQNPFAFDKAINSASFDHHWGYQGELGCRVEDNQAHFSLWSPTATEVQVVVYES
                     AANDAPVWKTFEMKRGNSYSYNHKDNTIGVWSLDVEEDLVGKTYQYQVQFPHHQTLTR
                     DPYTIATSPDGKRSAILSHVEKQVENFEVKHGSEATWRLENPCKAVICEMHIRDLTKS
                     PTSGVDEHLRGTFLGAAQAGTVNQYGQSTAFDYIKKLGYNYVQLQPIADRHKEYDEDG
                     NVTYNWGYDPQNYNAPETSFSTNPDDPAQVIRDLKVMVQAYHDAGIGVIMDVVYNHTF
                     SVVDAPFQTTVPDYYYRMNPDGTFQNGTGVGNETASEHEMFRKYMIDSLLYWVQEYNI
                     DGFRFDLMGIHDVKTMQMIRQSLDEIDSNIILYGEGWDMGTGLAPYDKAKKDNAYQMP
                     NIGFFNDNQRDAVKGGEVYGAIKSGFVSGAATEPILAKAILGSRELGSYTHPNQVLNY
                     VEAHDNYNLHDLLATLHPDQSSEQIMRKVETATAMNLLMQGMAFMEIGQEFGRTKLVA
                     TGENGELTHDDRERAMNSYNAPDSVNQVNWNLINERQDSIEFIRQVIRLKTKTGAFSY
                     SSYDEIYHHVFVHSAIEHSGYLIYEVHGKEHLLVVVNAKSEPYQFENAGNLAMLVTNS
                     RSKEDNVLNDISLAVLSVL"
     gene            complement(4568..6526)
                     /gene="ligA"
                     /locus_tag="VU534_001906"
     CDS             complement(4568..6526)
                     /gene="ligA"
                     /locus_tag="VU534_001906"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HEU1514439.1"
                     /translation="MNKRMNELVALLNRYATEYYTSDNPSVSDSEYDRLYRELVELET
                     AYPEQVLADSPTHRVGGKVLDGFEKYSHQYPLYSLQDAFSCEELDAFDARVRKEVAHP
                     TYICELKIDGLSISLTYEKGILVAGVTRGDGSIGENITENLKRVKDIPLTLPEELDIT
                     VRGECYMPRASFDQVNQARQENGEPEFANPRNAAAGTLRQLDTAVVAKRNLATFLYQE
                     ASPSTRDSQEKGLKYLEQLGFVVNPKRILAENIDEIWNFIQEVGQERENLPYDIDGVV
                     IKVNDLASQEELGFTVKAPKWAVAYKFPAEEKEAQLLSVDWTVGRTGVVTPTANLTPV
                     QLAGTTVSRATLHNVDYIAEKDIRKDDTVIVYKAGDIIPAVLRVVESKRVSEEKLDIP
                     TNCPSCNSDLLHFEDEVALRCINPRCPAQIMEGLIHFASRDAMNITGLGPSIVEKLFA
                     ANLVKDVADIYRLQEEDFLLLEGVKEKSAAKLYQAIQASKENSAEKLLFGLGIRHVGS
                     KVSQLLLQYFHSIENLSQADSEEVASIESLGGVIAKSLQTYFATEGSEILLRELKETG
                     VNLDYKGQTVVADAALSGLTVVLTGKLERLKRSEAKSKLESLGAKVTGSISKKTDLVV
                     VGADAGSKLQKAQELGIQVRDEAWLESL"
     gene            complement(6619..7797)
                     /locus_tag="VU534_001907"
     CDS             complement(6619..7797)
                     /locus_tag="VU534_001907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001083019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEU1514440.1"
                     /translation="MNRYAVQLISRGAINKMGNMLYDYGNSVWLASMGTIGQTVLGMY
                     QISELVTSILVNPFGGVISDRFSRRKILMTADLVCGILCLAISFIRNDSWMIGALIVA
                     NIVQAIAFAFSRTANKAIITEVVEKDEIVIYNSRLELVLQVVGVSSPVLSFLVLQFAS
                     LHMTLLLDSLTFFIAFVLVAFLPKEEAKVQEKKAFTGRDIFVDIKDGLHYIWHQQEIF
                     FLLLVASSVNFFFAAFEFLLPFSNQLYGSEGAYASILTMGAIGSIIGALLASKIKANI
                     YNLLILLALTGVGVFMMGLPLPTFLSFSGNLVCELFMTIFNIHFFTQVQTKVESEFLG
                     RVLSTIFTLAILFMPIAKGFMTVLPSVHLYSFLIIGLGVVALYFLALGYVRTHFEKLI
                     "
     gene            complement(7877..8740)
                     /locus_tag="VU534_001908"
     CDS             complement(7877..8740)
                     /locus_tag="VU534_001908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012291596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE/MutR family transcriptional regulator"
                     /protein_id="HEU1514441.1"
                     /translation="MEHLGKVFREFRTSGNYSLKEAAGESCSTSQLSRFELGESDLAV
                     SRFFEILDNIHVTIENFMDKARNFHNHEHVSMMAQIIPLYYSNDIAGFQKLQREQLEK
                     SKSSTTPLYFELNWILLQGLICQRDASYDMKQDDLGKVADYLFKTEEWTMYELILFGN
                     LYSFYDVDYVTRIGREVMEREEFYQEISRHKRLVLILALNCYQHCLEHSSFYNANYFE
                     AYTEKIIDKGIKLYERNVFHYLKGFALYQKGQCKEGCKQMQEAMHIFDVLGLPEQVAY
                     YQEHYEKFVKS"
     gene            complement(8743..10644)
                     /locus_tag="VU534_001909"
     CDS             complement(8743..10644)
                     /locus_tag="VU534_001909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000584877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEU1514442.1"
                     /translation="MIILQANKIERSFAGEVLFDNINLQVDERDRIALVGKNGAGKST
                     LLKILVGEEEPTSGEINKKKDISLSYLAQDSRFESENTIYDEMLHVFNDLRRTERQLR
                     QMELEMGEKSGEDLDKLMSDYDRLSENFRQAGGFTYEADIRAILNGFKFDESMWQMKI
                     AELSGGQNTRLALAKMLLEKPNLLVLDEPTNHLDIETIAWLENYLVNYSGALIIVSHD
                     RYFLDKVATITLDLTKHSLDRYVGNYSRFVELKEQKLVTEAKNYEKQQKEIAALEDFV
                     NRNLVRASTTKRAQSRRKQLEKMERLDKPEAGKKSANMTFQSEKTSGNVVLTVENAAV
                     GYDGEVLSQPINLDLRKMNAVAIVGPNGIGKSTFIKSIVDQIPFIKGEKRFGANVEVG
                     YYDQTQSKLTPSNTVLDELWNDFKLTPEVEIRNRLGAFLFSGDDVKKSVGMLSGGEKA
                     RLLLAKLSMENNNFLILDEPTNHLDIDSKEVLENALIDFDGTLLFVSHDRYFINRVAT
                     HVLELSENGSTLYLGDYDYYVEKKATAEMSQTEEASTSNQAKEASPVNDYQAQKESQK
                     EVRKLMRQIESLEAEIEELESQSQAISEQMLETNDADKLMELQAELDKISHRQEEAML
                     EWEELSEQV"
BASE COUNT         3264 a         2382 c         1929 g         3272 t
ORIGIN      
        1 caatgtatta tatatagtaa aatgaaataa taacaggaca aatcgatcag gacagtcaaa
       61 tcgatttcta acaatgtttt agaagtagag gtgtactatt ctggtttcaa tctattataa
      121 taccaaaaag ttcgtatttt ttctataatt attattattt tatagcaaaa aaataaaacc
      181 aggaaaacaa tttcctggtt ttacacgtta tttcacatca aaaacaatgg atttgacatt
      241 tgtcatcgct tcaatgctat atttaattcc ttgcactcca gctccagaac ctttgacacc
      301 aaggaatggg aaattatctg gaccacgctg ggttttatta ttaatgtgga ctgtacctac
      361 ttcaagtttt tcagcaattt caaaggcttt tttgaaatca tttgtaaaga ctgatgattg
      421 aaggccgaat tcagattcgt tggcaaaggc aatagcttcc tctacactag ccacacgaat
      481 gattggtaaa acaggaccaa atggctcttc ccatgccact ttcatatctt ttgtaacttg
      541 gtcaaaaagc actggccaga gaagattgcc ctcacgtttg attggtgtaa gagcctgagc
      601 ttctttttct tgtgcatcct caatcaagcc ccaaatgaag tcggctgaag cattgtcaat
      661 aacaggtgta atatcagcat tgtcaaatgg atcaccaact gttaatttag aaacttcttc
      721 ctgaagcaaa gtagctaatt tatctgctac actttcgaga acaatgacac gtttaatggc
      781 cgtgcaacgt tgtcctgagt agctaaaggc tcccgcaaca atttgcttgg cagcatgttc
      841 caaatctgca tcttctagta caagagctgc atctttccca ccaagttcca acatgatagg
      901 acgcatacca gctaaacgac caatacgttc tccaatagga gttgaacctg taaagttgat
      961 gaagttgact tctttgtgct caatgatata atccccaatt tctgaaccac gacctgtaat
     1021 ggtgttgaaa acacctgccg gaatccctgc ttcttcaaat gctttagcca acaagagtcc
     1081 agaaatggaa ccttgtgttg gtggcttaaa catgaccaca ttccctgcaa tcaaggcagg
     1141 tgcaatttta gaagcagata aattaactgg ataattaaag ggagcaatcg ctagcacgat
     1201 accaactggt tcacgacgga caacagccag tttgttttta cttgttgcct caaaaccacc
     1261 accttccatt gcttgtccag tgatacggag accttcctca gcagcataac gaatcaagtc
     1321 tgctgtacgc actacttctc caattgctgc tttaatccct tttgctactt ctttggcaag
     1381 gatagtacca atttcttcct tatcgcgttc taaaatagct gctgttttat gcaaataagc
     1441 cgcacgttca actgctgata aagctcgcca tgctggcagg gctgcacgcg cagcttgcat
     1501 agcctcatca gcttcagtct gagtcatggc tggaactgta cccaattctt cttgattgat
     1561 tggtgaataa atcgtaattt cttgttcaga tgatttccat tttccattta ctaaattctg
     1621 atatcttgtc aaatttttgt cctcctgaaa atgattaaga tatattttac caaattttca
     1681 gaaaatcaca accctttttg caaaattttt gagattattt tcacaaactt gatttttcaa
     1741 agtatactca ataaaaatta aaaaaatcca ctacgtcaag gcgaggctaa tgtggtttga
     1801 agaaattttc gaagagcgtg aatgagtatc atctatagta aaataaaaaa actgaacaat
     1861 ttggttgggg acagccaaac caatttctca caatgtttca gaaacaaggg tgtgctattc
     1921 caatttcagc ctactataac tgtcatagat tgctgaaaca aagtctaggt aaaagtcttc
     1981 ataataaaaa gacctcctat caagtgttca aaaactttga taggaggtct tgttttgtga
     2041 aaatatttat caaattttct atacaagtga gctgttagcc aggttctttc tattctttca
     2101 atttcaatga atggattttt tactaatact cataactggg aatttgtctg tgtaaaaata
     2161 gcgagataga tggtatttat aaaacactca agacagctag actaatatca tttaaaacat
     2221 tatcttcttt tgagcgactg ttggttacca acatagctaa atttcctgca ttttcaaatt
     2281 gatagggttc tgatttagca ttcacaacca ccaagaggtg ttctttgccg tgaacttcat
     2341 agataaggta gccgctatgt tcaatcgcag aatgcacaaa gacatgatgg taaatttcat
     2401 catagctaga gtaagaaaag gcaccagttt ttgtcttcaa tcggatgact tgacggataa
     2461 actcaatact gtcttgacgc tcattaatca agttccagtt cacttggttc acactgtcag
     2521 gagcattata gctattcatc gcacgctctc tatcatcatg ggtcaactca ccattttcac
     2581 cagtcgcaac cagtttggta cgaccaaatt cttgaccgat ttccataaag gccatcccct
     2641 gcatgagcag attcatggct gtggcagttt cgaccttgcg catgatttgc tctgaacttt
     2701 ggtctggatg aagggttgcc aataaatcgt gaagattgta attgtcatgg gcttctacat
     2761 agttaagcac ctgatttgga tgtgtatagc ttcctaattc acgacttcct aggattgctt
     2821 tagctagaat tggctctgtc gcagcaccac tgacaaaacc tgacttgata gcaccataaa
     2881 cttctccccc tttgacagca tcgcgctgat tgtcattaaa gaaaccaata tttggcatct
     2941 ggtaggcatt gtccttcttg gccttatcat aaggggcaag acctgttccc atatcccatc
     3001 cttctccata gaggataatg ttggagtcga tttcatccaa gctttgacga atcatctgca
     3061 tggtcttgac atcatgaatc cccatcaagt caaaacggaa gccgtcaata ttatattcct
     3121 gcacccagta tagaagagaa tcaatcatat acttgcgaaa catttcgtgt tcactggctg
     3181 tttcatttcc aacacccgtt ccattctgga aggtaccatc tggattcata cgataatagt
     3241 aatcagggac tgttgtttgg aatggtgcat caacaactga gaaggtatgg ttatagacta
     3301 catccataat gactccaata cccgcatcgt gataagcttg aaccatcacc ttcaaatcac
     3361 gaatgacctg agctggatca tctggattag ttgaaaaact agtttctggc gcgttatagt
     3421 tttgtggatc ataaccccag ttgtaggtta catttccatc ctcatcgtat tctttatgac
     3481 ggtctgcaat tggttgcaat tgaacataat tgtagcccag cttcttgatg taatcaaaag
     3541 cagttgactg gccgtattgg ttaactgttc cagcctgagc agcacccaag aaagttcctc
     3601 gaagatgttc atctacaccc gatgtaggtg atttagtcaa atcacgaatg tgcatttcac
     3661 agataactgc cttacatgga ttttccaagc gccaagtagc ctccgaaccg tgcttaacct
     3721 cgaagttttc aacttgcttt tctacatggc tcagaatagc tgaacgtttg ccatcagggc
     3781 tggtcgcgat tgtataagga tcacgtgtca gtgtttggtg atgagggaat tggacttgat
     3841 actgataagt cttacctacc aaatcttctt caacatccaa actccagaca ccgattgtat
     3901 tgtccttatg attataagag tagctattgc ctcttttcat ctcaaaagtc ttccaaacgg
     3961 gtgcatcatt agcagctgat tcataaacga caacttgcac ttctgtcgct gtaggtgacc
     4021 agagagaaaa atgagcctga ttgtcctcta cacggcaacc caattctcct tggtaacccc
     4081 aatgatgatc aaaactagca ctgttaatgg ccttatcaaa ggcaaaagga ttttgatttt
     4141 tatagaaagg actggcaata gcaggatttt cagagtaata aatcctatca tcgccttcca
     4201 aaatccagac ctctgttaat aggggatagt gattaaaacg gatagaatat tctttactag
     4261 tttgacctgt atgaaccaca aaattcaagc tttctataac atgtgaactt gggtgttcaa
     4321 agctaaataa agctccaaaa taatcttctt tgtaggttag caaatcaatt cgttgatcct
     4381 gactttttac aaaggagcaa gtgtcatatt ctccattctt acgatggtaa tgaatgcgca
     4441 tagggtagtt atacattttt tatttttcct ttttactttg tttctatttc actaataaat
     4501 ttttgtcaat ctcgtctcaa ttaacagaca tagtcatatt ctctaaactc tgtttttaaa
     4561 cgatccatta caaactttct agccatgcct catctctgac ctggatacca agttcttgtg
     4621 ctttttgcag tttacttcca gcgtctgcac ctaccacgac gaggtcggtc tttttagaaa
     4681 tactacctgt cactttggca cccagacttt cgagtttact tttagcttct gagcgcttga
     4741 gtcgttccaa ttttcctgtc aataccacgg tcaaacctga caaggccgca tccgctacta
     4801 ccgtctgtcc tttatagtcc agattgaccc cagtttcttt caattctctg agcagaattt
     4861 cagagccttc tgtcgcaaaa taagtctgaa gacttttggc aatcacgcca cctagacttt
     4921 caatactagc cacttcctct gaatctgcct gagacagatt ttcaattgaa tggaaatatt
     4981 gaagtaaaag ctgactaacc ttgcttccga catgacgaat tcccaaacca aataagagct
     5041 tctcggcaga attttccttt gatgcttgga tagcctgata cagtttagca gcggactttt
     5101 ccttaactcc ctctaaaagg aggaaatcct cttcttgcaa acgataaata tccgccacat
     5161 ccttgactaa attagcagca aaaagcttct caacaataga tggaccaagg cctgtaatat
     5221 tcatagcatc acgagaagca aagtgaatca agccttccat gatttgagca gggcaacgcg
     5281 gattgataca acgtagggcc acttcatctt caaagtgcaa caagtcagag ttacaacttg
     5341 gacagtttgt agggatatct agtttttctt cagaaacccg tttggactct accacacgta
     5401 aaacggcagg gatgatgtca ccagccttat atacaatgac cgtatcgtct tttcggatat
     5461 ctttttcagc aatataatct acattgtgca gggtcgcacg gctaacagtc gtaccggcaa
     5521 gttgtactgg tgttagatta gcagttggag ttacaacacc ggtacggcca actgtccagt
     5581 caactgataa gagttgagct tctttttctt cggcagggaa cttgtaggct actgcccact
     5641 ttggagcctt aactgtaaaa ccaagttctt cttgacttgc taggtcgttg accttgatta
     5701 ccactccatc aatatcgtaa ggcagatttt cccgttcctg tcctacttct tggataaaat
     5761 tccagatttc atctatgttt tcagccaaga ttcgcttagg attgaccaca aaacctagtt
     5821 gttctaggta cttcaaaccc ttttcttggc tatcacgagt tgaagggctg gcttcttgat
     5881 agagaaacgt tgcaagatta cgcttggcaa ctactgctgt atccaactga cgcagagttc
     5941 ctgctgccgc attacgagga ttagcaaatt caggctctcc attttcttgg cgcgcttggt
     6001 taacttggtc aaaggaagcg cgtggcatgt aacattcccc acgaactgtg atatctagtt
     6061 cttctggcaa agtcaaaggg atgtccttaa cacgcttgag gttttctgtg atattttcac
     6121 caattgaacc atctccacgt gttaccccag caaccaaaat ccccttttca taagtcagcg
     6181 agatagataa gccatcgatt ttcagctcac aaatataggt cggatgagcc acttccttac
     6241 gaacacgcgc atcaaaagca tctagctcct cacatgaaaa agcatcctgc aaactataaa
     6301 gaggatactg atgactgtat ttttcaaaac catctaaaac cttgccacca acacgatgag
     6361 tcggactgtc tgctagcact tgctctggat aagcagtttc taactcgacc aactcacggt
     6421 aaaggcggtc atactcactg tctgaaaccg agggattatc gctggtatag tactcagtcg
     6481 catagcgatt gagcaaagcg actaactcat tcattctttt attcataaga ccattttacc
     6541 ataaaacaag ccctcctcac aaacgagaag ggcggaaaaa acacttagtt tgaaattatt
     6601 tttgaaactc aagcaacctt atatcaattt ttcaaaatga gttcgaacat atccgagagc
     6661 taagaaatat aaggctacaa ctccaagtcc aataatcaag aaagaataaa gatggacact
     6721 tggcaagact gtcataaatc cttttgcaat aggcataaat agaatagcta aggtaaaaat
     6781 tgtactcagt actcttccaa gaaattcgct ctcaaccttg gtttgtactt gagtaaaaaa
     6841 gtgaatatta aaaatcgtca taaacaattc acaaactaaa tttccagaaa aggaaagaaa
     6901 agttggaagt ggtaatccca tcataaaaac tccgacacct gtcaaagcca gtaaaatcaa
     6961 aagattataa atattagctt taattttact agctagaaga gccccaatga tggaaccaat
     7021 agcccccata gttaaaatac ttgcataggc tccttctgac ccgtaaagct gattcgaaaa
     7081 gggaagtaga aattcaaaag ctgcaaaaaa gaaattaacg ctggaagcta ccagcaaaag
     7141 gaagaaaatt tcttgctgat gccagatata gtgtaaccca tccttgatat ctacaaaaat
     7201 atctctccca gtaaaagcct ttttctcttg aacttttgct tcctcttttg gaaggaaagc
     7261 cactagaaca aaagcaatga aaaaagtcag cgagtctagc agtagcgtca tatggagact
     7321 tgcaaactgt aaaacaagga aggaaagaac aggagagcta acacctacaa cctgcaaaac
     7381 cagctctaag cgagaattat agatcacaat ctcatctttc tccaccactt cagttatgat
     7441 agctttattg gctgtgcgag aaaaggcaaa agcaatagcc tgcacaatgt tagcaacaat
     7501 caaagcgcca atcatccagc tatcattcct tatgaaagaa atagccagac aaagaatccc
     7561 acaaacaaga tctgccgtca ttaaaatctt acgacgagaa aaacggtctg aaataactcc
     7621 gccaaaggga ttgacgagaa tagatgtgac gagctcagaa atctgataca ttcctaaaac
     7681 tgtctgtcct atagtcccca tagaagccaa ccagacacta tttccataat catagagcat
     7741 atttcccatt ttattgatag ccccacggct aatcaactgc actgcatagc gattcatatt
     7801 aaagctcctc tcaaattttg aaactattgt atcaaaaccg aaaggagctt tttatttttt
     7861 cccttatttg ggaaaattaa cttttgacaa atttttcgta gtgttcctga taataggcta
     7921 cttgctctgg aagacctaac acatcaaaaa tatgcatggc ctcttgcatc tgcttacagc
     7981 cttctttaca ctgtcctttt tgatataagg caaaaccttt taaataatgg aaaacattac
     8041 gctcataaag cttaatacct ttgtcaataa tcttctctgt ataagcctca aaatagttgg
     8101 cattataaaa agaagaatgc tctaaacaat gctggtaaca attgagggcc aaaatcaaca
     8161 ctaatctctt atggcgacta atctcttggt aaaattcctc cctctccata acttctctac
     8221 caatccgagt gacatagtct acatcgtaga aactatagag gttaccgaaa agaatcaact
     8281 catacatggt ccattcttct gttttgaaga gataatctgc taccttaccc aaatcatcct
     8341 gcttcatatc ataactcgca tctctttgac aaatcagacc ttgtagcaaa atccagttca
     8401 gctcaaaata aaggggagtc gtcgaactct tagacttttc aagttgttct ctttgaagct
     8461 tttgaaaacc tgcaatatcg tttgaatagt aaagtgggat aatctgtgcc atcatagaca
     8521 catgttcatg attatgaaaa ttccttgcct tatccatgaa attttcgatt gttacatgaa
     8581 tgttatccaa aatctcaaag aaacgggaga ctgccaggtc agactcccca agctcaaagc
     8641 gagataactg agaggtagag caggattcgc ctgctgcttc ctttaaagaa taatttccac
     8701 ttgttcgaaa ttcacgaaat acttttccaa gatgttccat ctttacacct gctctgataa
     8761 ttcttcccac tcaagcatag cttcttcctg acgatggctg attttgtcca gctcagcctg
     8821 taattccatg agtttgtcgg catcgtttgt ttccaacatt tgttcagaaa tggcttggct
     8881 ttgactttct agctcttcaa tttcagcttc tagactttcg atttgtcgca tgagtttgcg
     8941 aacttctttt tgactttctt tctgggcctg atagtcattg actggacttg cttcctttgc
     9001 ttgattgcta gttgaagctt cctcagtctg actcatttct gctgttgctt tcttctcaac
     9061 atagtagtcg taatctccaa ggtagagagt tgaaccattc tcagacaatt ccaaaacatg
     9121 agttgccaca cgattgataa agtaacgatc atgactgaca aacagcaagg ttccatcaaa
     9181 gtcaatcaag gcattttcta gcacttcctt actatcaata tccaagtggt tggtcggctc
     9241 atccagaatc aaaaagttat tgttttccat agacaattta gctaaaagca aacgagcttt
     9301 ttcgccacca gatagcatgc cgactgattt tttaacatca tctcctgaga aaaggaaggc
     9361 tccaagacgg ttgcggattt caacttctgg tgtcagtttg aaatcattcc agagttcatc
     9421 cagcaccgta ttacttggtg tcagcttgct ttgggtttgg tcatagtaac caacctcaac
     9481 attagcgcca aagcgctttt ctcccttgat aaaaggaatc tggtccacaa tagacttgat
     9541 aaaggttgac ttgccgatac catttggacc aacgatagcg acagcattca tcttacgaag
     9601 atctaggtta atcggttgtg acaagacttc cccgtcatag ccaacagctg cattttcaac
     9661 agtcaaaaca acattgcccg acgttttttc agactggaag gtcatgttgg ctgatttctt
     9721 gccagcttca ggcttgtcca aacgttccat tttttccagt tgtttacggc gagattgagc
     9781 acgtttagtc gttgaagcac gaactagatt gcgattgaca aagtcttcca gagcagcgat
     9841 ttccttctgt tgcttttcat agttttttgc ctcagtaact agcttttgct ccttcaattc
     9901 gacaaaacga gagtaattcc ccacatagcg atccaaggaa tgcttggtca aatctagcgt
     9961 aattgtcgca accttgtcca agaaataacg gtcgtggctg acgataatga gggcaccgct
    10021 atagtttacc aagtaattct ctagccaggc gatggtttca atatccaagt ggttagttgg
    10081 ctcgtccaag accaagagat tgggcttttc aaggagcatt ttggcaagtg ccaaacgagt
    10141 attttgacca ccagaaagct cagcaatttt catctgccac atagactcgt caaacttgaa
    10201 tccattcaaa atcgctcgaa tatcagcttc ataggtaaag ccacctgctt ggcgaaaatt
    10261 ctcagataag cggtcataat ctgacatcag tttatccaaa tcctcaccag acttttcacc
    10321 catctccagc tccatctgac gcagttgtct ctccgtccga cgcaaatcat taaagacatg
    10381 aagcatttca tcgtagatgg tattttcaga ctcaaaacgg ctatcttggg ctaggtaaga
    10441 cagagaaata tcttttttct tattgatttc tccgctagtt ggctcctctt ctccaactaa
    10501 aatcttcaaa agagtagact tacctgcacc atttttccca acaagagcaa tccgatctcg
    10561 ttcatcaacc tgcaggttga tattatcgaa aagaacctct cctgcaaaag aacgttcaat
    10621 tttattagct tgtaaaataa tcatacaagt agtatagcat gtttccctaa ggcattcaag
    10681 ataatcgtaa gtcttttagt acaactttta taacataaaa taaactaaat tatgtatatt
    10741 ttatattaga ttacttcact atcttgttgg attttctaac cagctaatct tgtttcaaat
    10801 agttatcgca caagtctatt atttaattct tttcatcatt tacgtac
//
LOCUS       DAVFER010000062        10449 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1105170250
            SAMEA2167659-rid19724873.denovo.062, whole genome shotgun sequence.
ACCESSION   DAVFER010000062 DAVFER010000000
VERSION     DAVFER010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2167659
            Sequence Read Archive: ERR388902
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10449)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10449)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928716.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928716.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 04:07:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,118
            CDSs (total)                      :: 2,073
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 120
            CDSs (without protein)            :: 120
            Pseudo Genes (ambiguous residues) :: 0 of 120
            Pseudo Genes (frameshifted)       :: 67 of 120
            Pseudo Genes (incomplete)         :: 47 of 120
            Pseudo Genes (internal stop)      :: 34 of 120
            Pseudo Genes (multiple problems)  :: 23 of 120
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10449
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2167659-rid19724873.denovo.062"
                     /strain="1105170250"
                     /db_xref="taxon:1313"
     gene            complement(<1..782)
                     /locus_tag="VU534_001910"
     CDS             complement(<1..782)
                     /locus_tag="VU534_001910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HEU1514443.1"
                     /translation="MTKTLKRPEVLSPAGTLEKLKVAVQYGADAVFIGGQAYGLRSRA
                     GNFTFEQMEEGVQFAAKYGAKVYVAANMVMHEGNEAGAGEWFRKLRDIGIAAVIVSDP
                     ALIMIAVTEAPGLEIHLSTQASATNYETLEFWKELGLTRVVLAREVSMEELAEIRKRT
                     DVEIEAFVHGAMCISYSGRCTLSNHMSMRDANRGGCSQSCRWKYDLYDMPFGKERKSL
                     QGEIPEEFSMSAVDMSMIDHIPDMIENGVDSLKIEGRMKSIH"
     gene            1406..1588
                     /locus_tag="VU534_001911"
     CDS             1406..1588
                     /locus_tag="VU534_001911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001262531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ApaLI family restriction endonuclease"
                     /protein_id="HEU1514444.1"
                     /translation="MANDNKSHYLIYRVLGISFEEGENIDLYQNKGRFLYKYAGSFLE
                     EAAVLCFNEKFGTENT"
     gene            1598..1963
                     /locus_tag="VU534_001912"
     CDS             1598..1963
                     /locus_tag="VU534_001912"
                     /inference="COORDINATES: protein motif:HMM:NF021048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ApaLI family restriction endonuclease"
                     /protein_id="HEU1514445.1"
                     /translation="MPNSESTKPKTFEIDCLVGEKHAYEIKWWDATTDGDHITKEHTR
                     IKVIHNKGYIPIRLMFYYPNRTQAIKIQQTLETLYNGIGGKYYYGDSAWEHLRAVTGI
                     DLLSILTDIANKKTGVKSK"
     gene            1960..3150
                     /locus_tag="VU534_001913"
     CDS             1960..3150
                     /locus_tag="VU534_001913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="HEU1514446.1"
                     /translation="MTVLKGDNLEILKTIESSSIDLIYMDPPFFTQKTQKLSNNKNIM
                     YSFEDTWTSIEDYKEFLSVRLEECKRVLKNSGSIFVHCDKIANHHIRLILDNIFGVDM
                     FQSEIIWNYKRWSNSKKGLLNNHQNIYFYSKSKDFKFNTIFTEYSSTTNIDQILVERK
                     RDGNSKTIYKVDNNGNYILAKEKNGVPLSDVWNIPFLNPKAKERVGYPTQKPILLLEQ
                     IIKIATDKNDIVLDPFCGSGTTLVASKILNRNYMGIDLSEEAINITQQRLENVIKTSS
                     NLLNKGIEAYRTKTEEEENILKLLQAKIVQRNKGIDGFLPKHFQKKPIPIKIQKNNEC
                     LNESISLLQNAINSKKLDFGVVIKTHSDNLLFDFDTIPENIIVVDHFELTIEKWLSKS
                     QQLL"
     gene            complement(3660..4652)
                     /locus_tag="VU534_001914"
     CDS             complement(3660..4652)
                     /locus_tag="VU534_001914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000122906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU1514447.1"
                     /translation="MSYYDFVKDYMKVDECKNNEKYSSAGHTFCWKKENSTYAEGLYW
                     FYEGGSFIIDIHDFYIKEEVVQNSTYSMSDYVSIYSSYIVSANGEKFNPYQTITANSL
                     CTFDFDNIKDNFVFLLHENCCYLAVSIGFKKELIEKHLASININPESFYSTLLQPNQI
                     ILTKALERVAMEILNCKMDAPAADFFFKAKANEWISIVIDTYLNRKKYKIEIDDDKAL
                     EDVARFLDDHFATNVNQGTLEKISKMSGTKLKNLFKEKYCQSITEYTQRKRMNVAETL
                     LLNTELPIKEIAESVGYSSASKFSIYYKRYKGKLPSEVRNLACKHHNFKCDYCD"
     gene            4812..6566
                     /locus_tag="VU534_001915"
     CDS             4812..6566
                     /locus_tag="VU534_001915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU1514448.1"
                     /translation="MKIYKKLFAYVQDKKYLGVLAIIFSAISAALTVYGYYLIYKFLD
                     KLIINSNLSGAESIALKSVITLTSGAIFYFVSGMFSHILGFRLETNLRKRGIDGLEKA
                     SFRFFDLNPSGQIRKIIDDNAAQTHQVVAHMIPDSSQAIITPVLVLALGFIVSIRVGI
                     ILLALTIIGGLILGAMMGEQEFMKIYQESLSKLSAETVEYVRGMQVVKIFKANVESFK
                     SFYKAIKDYSKYAYDYSLSCKRPYVLYQWLFFGLIAILIIPIVYFMTSLASAKVILLE
                     LIMILFLSGVLFVSFMRMMWYSMYISQGNYAVDTLEALYEDMQKDKLVHGNVNNFKNY
                     NIEFENVSFAYNDKAVIENLSFNLEEGKSYALVGSSGSGKSTVAKLISGFYNVNKGSI
                     KIGGIAISEYSDEALIKAISFVFQDSKLFKKSIYDNVALANKDATKDDVMRALKLAGC
                     DLILDKFPERENTIIGSKGVYLSGGEKQRIAIARAILKDSKIIIMDEASASIDPDNEF
                     ELQKAFKNLMKDKTVIMIAHRLSTIKDLDEIIVMDSGKIIERGSDKELMSKDTRYKSL
                     QEMFNSANEWRVSNERVL"
     gene            6550..8271
                     /locus_tag="VU534_001916"
     CDS             6550..8271
                     /locus_tag="VU534_001916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019214631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU1514449.1"
                     /translation="MKEFYKKRFALTDGGARNLSKATLASFFVYCINMLPAILLMIFA
                     QEVLENMGKSNGFYIVFSVLILIAMYILLSIEYDKLYNTTYQESADLRIRTAENLSKL
                     PLSYFSKHDISDISQTIMADIEGIEHAMSHSIPKVGGMVLFFPLISVMMLAGNVKMGL
                     AVIIPSILSFIFIPLSKKYQVNGQNRYYDVLRKNSESFQENIEMQMEIKAYNLSKDIK
                     DDLYKKMEDSEKVHLKAEVTTILTLSISSIFSFISLAVVIFVGVNLIINKEINSLYLI
                     GYLLAAMKIKDSLDASKEGLMEIFYLSPKIERLKEIQNQDLQEGDDYSLKKFDIDLKD
                     VEFAYNKDAKVLNGVSFKAKQGEVTALVGASGCGKTTILKLISRLYDYDKGQILIDGK
                     DIKEISTESLFDKVSIVFQDVVLFNQSVMENIRIGKQDASDEEVKRAAKLANCTDFIE
                     KMDKGFDTVIGENGAELSGGERQRLSIARAFLKDAPILILDEITASLDVNNEKKIQES
                     LNNLVKDKTVVIISHRMKSIENADKIVVLQNGRVESEGKHEELLQKSKIYKNLIEKTK
                     MAEEFIY"
     gene            8282..8911
                     /locus_tag="VU534_001917"
     CDS             8282..8911
                     /locus_tag="VU534_001917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000368976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HEU1514450.1"
                     /translation="MDNKKLKVKDLVSIGVFGVIYFAFMFGVGMMGLIPILFLIYPTV
                     LAIVAGTVVMLFMAKVQKPWALFIFGMISPLVMFAAGHTYVVVVLSLIVMIIAELIRK
                     IGNYNSFKYNMLSYAIFSTWICSSLMQMLLAKEKYMEWSLMTMGKDYVDVLEKLITYP
                     HMALVALGAFLGGILGAYIGKALLKKHFSNGLYCVGYFTPCLILWCYLN"
     gene            8812..9369
                     /locus_tag="VU534_001918"
     CDS             8812..9369
                     /locus_tag="VU534_001918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001851583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEU1514451.1"
                     /translation="MYRQGSIEKTLFKWIILCGILYSLPNFMVLSELNPIVKMFLSIP
                     IVIRMFILPFMAASFMIKTSDVGAIISSMDKLKISKNVSIPIAVMFRFFPSFKEEKKN
                     IKMAMRVRGINFKNPVKYLEYVSVPLLIISSNISDDIAKAAETKAIENPIAKTRYIRV
                     KIQLIDFVYVLAVAGLIVGGLIWLK"
     gene            9357..>10449
                     /locus_tag="VU534_001919"
     CDS             9357..>10449
                     /locus_tag="VU534_001919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002837029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU1514452.1"
                     /translation="MVEIKNLSLDYGEEHILDDISLSIAEGECVLFTGKSGNGKSSLI
                     NSINGLAVRYDNAKTKGEIIIDGKNIKNLELYQISMLVSTVFQNPKTYFFNVNTTLEL
                     LFYLENIGLAREEMDRRLKDILEIFPIKNLLNRNIFNLSGGEKQILCIAASYIAGTKI
                     IVMDEPSSNLDIKSISVLAKMLKILKEKGISIIVAEHRIYYLMDIVDRVFLIDKGKLK
                     KTYTRSEFLKLDKNELNALSLRDKELSKLKVPYLKEGGEYQIKNLSYKFTDDECLSLK
                     DISFKLGKIYGIIGSNGRGKSTLLRCLIGLEKKSKEEIYFKGEKLSKKERLKNSSLVM
                     QDVNHQLFTDEVFNELRLGVKNFDEEKAKI"
BASE COUNT         3828 a         1487 c         1784 g         3350 t
ORIGIN      
        1 tagtgaatag acttcatacg tccttcgatt tttagactgt ccacaccatt ttcaatcata
       61 tctggaatgt ggtcaatcat agacatgtca acggctgaca ttgaaaattc ttctggaatc
      121 tcaccctgca aactcttacg ttctttccca aatggcatat cgtaaaggtc gtatttccaa
      181 cggcatgact gagaacatcc accacggttg gcatcacgca tactcatgtg gtttgaaaga
      241 gtacaacgtc cagagtatga aatacacata gctccatgga caaaggcttc aatttcaaca
      301 tctgtacgtt tgcggatctc agctaattct tccattgaaa cctcacgcgc taaaacgaca
      361 cgagtcaagc ctagctcttt ccagaactca agggtttcat agttagtggc actggcttgg
      421 gtagaaaggt ggatttcaag gcctggtgct tcagtcactg caatcataat caaggctggg
      481 tcagatacga taactgctgc aatcccgata tcacgcagtt tacggaacca ctcaccagca
      541 ccagcttcat ttccttcgtg cataaccata ttagccgcta catagacctt ggcaccatac
      601 ttggccgcaa actgcacgcc ttcttccatc tgttcgaaag taaagtttcc cgcacggcta
      661 cgaagaccat aggcctgacc accgataaag acagcatctg ctccatactg aacagctacc
      721 tttagcttct ctaaagtccc tgcaggtgat aaaacctcag gacgttttaa tgtttttgtc
      781 atgatttctc ctatttgcaa tataaaagtt tgacattttt ccttctcatt ttatagtaaa
      841 taaaggataa aatcaagcct agacggattg ttttgacaat tctaatcttt tagactttgc
      901 ataataactg ttaaacagtc gaaaattatc ccagttttaa caagtagtca aaaagtctag
      961 aaaagtaaaa accagtatcc caagatactg actcgtaaaa atacataaat tagtccttag
     1021 atgactactc ccactctgtt gctcctataa tggaaaagga ttgatacagt ctagaatatc
     1081 gcttttttat ttattattct gatataaaac tgttagaatt gattttttgt tttataccca
     1141 aatatgaata gagacgtagc taataagttg aataacatat ttggaaaaat gagaaatagc
     1201 aatattacta gaacttttag aaacaatcaa tatttaaaaa gaaaaaagct caaagaattt
     1261 attaaaccat gttataatag atatagctat aattttattt ataacaagag gatagaaatg
     1321 accgaattag aaagaaaaaa tcgaaaaatt agctaagaaa tattctgata acttaaacat
     1381 caaagttcaa gagagagttc gtgaaatggc aaatgataat aagagccatt atttgatata
     1441 cagagtttta ggtatttcat ttgaagaagg agaaaatatc gatttgtatc aaaataaagg
     1501 tcgtttttta tacaaatatg ctggttcatt tttagaagaa gctgcagtac tatgctttaa
     1561 cgaaaaattt ggtacagaaa atacttaaaa agttaacatt cctaattctg aaagtacaaa
     1621 acctaagact tttgaaattg attgtttagt cggagaaaaa cacgcatacg aaataaaatg
     1681 gtgggatgca actacagatg gagaccatat aactaaagaa cacactagaa taaaagttat
     1741 tcataacaaa ggatatatac caattcggtt aatgttctac tatccaaata gaactcaagc
     1801 tataaaaatt cagcaaactt tagaaacatt gtataacggt attggaggga aatattatta
     1861 tggagattct gcctgggaac atttaagagc agtgaccggt attgatttac ttagtattct
     1921 aacagatatt gcaaataaaa aaacaggggt aaaatcaaaa tgacagtatt aaaaggagat
     1981 aacttagaaa tattaaaaac tattgaatcc tcaagtattg atttaatcta tatggaccct
     2041 cctttcttta cacagaaaac ccaaaaatta tctaataaca aaaatattat gtattcattc
     2101 gaagatacgt ggacttcgat tgaggattac aaagaatttt tgtctgtaag attagaagaa
     2161 tgcaaaagag tgctaaaaaa tagtggcagt attttcgttc attgtgataa aattgcaaat
     2221 catcatatta gattaatttt agataatatc tttggagtag atatgtttca aagcgaaatt
     2281 atatggaact ataaacggtg gtctaattca aaaaagggat tattgaacaa tcatcaaaac
     2341 atttactttt attcaaagtc aaaagatttt aaatttaata caatttttac agagtattct
     2401 tctactacaa atatcgacca aatactagtg gaacgaaaac gagatggaaa ctctaaaact
     2461 atatataagg ttgataataa tggtaactat attctagcaa aagagaaaaa tggagttccc
     2521 ctttcagatg tttggaatat accatttctt aatccaaaag ctaaagaaag agtaggttat
     2581 cctacacaaa aacctattct gttattagaa caaattataa agattgctac tgataaaaat
     2641 gatatagttt tagacccgtt ctgtggaagt ggaactactt tagtagcctc caagattttg
     2701 aatagaaatt atatggggat tgatttatct gaggaagcta tcaatataac tcagcaacgt
     2761 ctggaaaatg ttataaaaac aagttcaaat ttattgaata aaggaatcga agcatataga
     2821 accaaaactg aggaagagga aaacattctt aaattattac aggcaaaaat tgttcaaaga
     2881 aataaaggaa ttgatggttt tttacctaaa cattttcaaa aaaaaccgat acctataaaa
     2941 attcaaaaaa ataatgaatg tctgaatgag agtatctctt tattacagaa tgctataaac
     3001 tccaaaaaac ttgattttgg agtagttata aaaactcatt cagataattt attatttgat
     3061 tttgatacga ttcctgaaaa tataatagta gttgaccatt ttgaacttac aatcgaaaaa
     3121 tggttaagta aaagtcaaca gttactatag tttgcaaatt atttacagaa agaacaaaaa
     3181 atgctctgaa acactgattt caaagcattt tttgttagtt taaaattact cccattcttc
     3241 ttttccaaac gtacaatata tccaaaacca ttcaaaatac tagattctat tttttataat
     3301 atcactaaat ccacctaatt ataggacgtt ttcagatttt tagtcccagt cccagtaccg
     3361 gagaaatatt gttttaatat aatatctctt tttgtcttct aagctcttaa aagcaaaaga
     3421 acaagtaaag agtcaagaca aggataaaaa gtccatatta gggcaaataa aaagctttaa
     3481 gacagatgac aaatctaagt caaataagaa agaccatagc aaaggtgcag agagataaat
     3541 attggcggtc ttcggactgc ctttattttt ttatccattt ttcaaatcaa atttattcag
     3601 actatatatg cacatataca cttaaattca tataaaaaca tggcttgtaa aaaattactt
     3661 taatcacaat aatcgcattt aaaattgtga tgtttgcaag ctaaattacg gacttcactt
     3721 ggaagttttc ccttgtatct tttataatag atagaaaatt tgctggcaga tgaatatcca
     3781 acagattctg ctatctcttt tataggtagt tcagtgttta aaagaagagt ttcagctaca
     3841 ttcattcttt ttctttgagt gtactctgta atgctttgac aatatttttc cttaaataaa
     3901 ttttttaatt tagtaccact cattttagat attttttcaa gcgtgccttg atttacattc
     3961 gttgcaaaat gatcatctaa gaatcttgct acatcttcaa gtgctttatc atcatcaatt
     4021 tcaattttat atttttttct atttaagtat gtgtcaatta ctatacttat ccattcattt
     4081 gcctttgctt taaagaaaaa atcagcggca ggagcgtcca tcttacaatt taatatttcc
     4141 attgccactc tttctaaggc ctttgtaagt attatttgat tcggttgaag caaggttgaa
     4201 taaaaagatt ctggattaat gttaatagat gctaaatgtt tttctattag ctctttttta
     4261 aaaccaatgg aaacagcaag ataacaacaa ttctcgtgta ataaaaaaac aaaattatct
     4321 tttatattat caaaatcaaa agtacataga gagtttgcgg taatagtttg atacggatta
     4381 aacttttctc cgtttgcact gacaatgtaa cttgaataaa ttgaaacata gtctgacata
     4441 ctataagtgc tattttgaac tacttcctct ttgatataaa aatcatgtat atcgataatg
     4501 aagctgcctc cttcataaaa ccaatatagt ccttctgcat aagttgaatt ctcttttttc
     4561 caacaaaatg tatgacctgc acttgaatac ttctcattgt ttttacattc atctactttc
     4621 atataatctt ttacaaaatc ataatatgac ataacacact atccctttta gacaatattc
     4681 caattagcct tattaattca aaactattgt attagtaatt ataacagatg tataatagaa
     4741 aagcaatgat agatattatc aattaagcga atttatatct aaaagggata ttaaagaaag
     4801 gagatatgct tatgaagatt tacaaaaaac tatttgctta tgtccaagat aagaaatatc
     4861 ttggggtttt ggccataatt ttttctgcta tatctgctgc acttacagta tatggatatt
     4921 atttaatcta caaatttcta gataagttaa taattaattc aaacttatcc ggtgcagaga
     4981 gtatagcatt aaaatctgtt attacactaa caagtggagc gatattttat tttgtctcag
     5041 gaatgttttc acatatcttg ggattcaggc ttgaaacaaa tttaagaaaa aggggaatcg
     5101 atggtctgga aaaagcaagt tttaggttct ttgacttaaa tccatctggt caaataagaa
     5161 agattataga tgacaatgct gcacaaactc atcaggtggt agcacacatg attcccgata
     5221 gttctcaggc aataatcaca cccgtacttg tacttgcact tggctttata gtaagtataa
     5281 gagttggcat aattttgctt gctcttacta taattggtgg cttaatttta ggggcaatga
     5341 tgggcgagca agaatttatg aagatatacc aagaatccct atctaaacta agtgctgaaa
     5401 ctgttgagta cgtgagagga atgcaagttg taaaaatatt taaagcaaat gtagagtctt
     5461 ttaaaagctt ttataaggcg ataaaagatt actcaaagta tgcttatgat tattccctat
     5521 cttgtaaaag gccttatgtt ttgtatcaat ggttattttt tggactgatt gcaattttaa
     5581 ttattcctat agtttatttt atgactagct tagctagcgc aaaggtgatt ttacttgagc
     5641 ttatcatgat tttattttta tcaggagttc tctttgtttc attcatgaga atgatgtggt
     5701 actccatgta tatttctcaa ggaaattatg cagtagatac tttagaggcg ctttacgaag
     5761 atatgcaaaa agacaaatta gtgcatggta atgtcaataa ttttaaaaac tataatatag
     5821 aatttgagaa tgttagcttt gcttataatg ataaagctgt cattgaaaat ttatccttta
     5881 atttagaaga aggaaagtcc tacgcacttg tcggttcatc tggatcaggc aaatcaacag
     5941 tagcaaaact tatatcaggt ttttacaatg ttaataaagg aagcataaag ataggcggga
     6001 tagcaataag tgaatattct gacgaagcct taattaaagc catttccttt gtttttcaag
     6061 attcaaaatt attcaagaag agcatttatg ataatgtagc gttagctaat aaagatgcga
     6121 cgaaagatga cgttatgaga gccttaaaat tagcaggatg cgatttaata ttagacaaat
     6181 tcccagaaag agaaaataca atcataggct caaaaggtgt ttatttatcc ggtggagaaa
     6241 aacaaagaat tgcaattgct agagcaattt taaaggattc caaaattatt attatggatg
     6301 aagcatcagc atctattgac ccagataacg agtttgaatt gcaaaaagct tttaaaaatc
     6361 ttatgaagga taaaacagtt atcatgattg cacacaggct atctacaatt aaagaccttg
     6421 atgaaattat tgtcatggat agtggaaaaa ttatagaaag agggtctgac aaagaattaa
     6481 tgtcaaaaga tacaaggtat aagagcctgc aagagatgtt taacagtgcg aatgaatgga
     6541 gggtttcaaa tgaaagagtt ttataaaaaa agatttgctc ttacagatgg aggagcaaga
     6601 aatttaagta aagcaacact ggcttcattt ttcgtttatt gtataaacat gcttcctgcc
     6661 atattactta tgatttttgc tcaggaagtt ttggaaaata tgggcaaaag caatggcttt
     6721 tatatagtat tctcagtttt gattttgata gcaatgtata ttttgctttc tatcgaatac
     6781 gataaattat ataacacaac ctatcaagaa agtgcagatt taagaataag gacagcggag
     6841 aatttatcaa aattacctct atcttacttt tctaaacatg acatttccga catttcacaa
     6901 acaatcatgg ctgatattga aggcatagag catgcaatga gccactcaat accaaaggtg
     6961 ggcggcatgg tactgttttt cccattaata tctgtaatga tgctagcggg caatgtcaag
     7021 atgggtttag ctgtaattat tccatctatt ttaagcttta tatttatacc tttatctaaa
     7081 aaatatcagg ttaatggaca gaatagatat tatgatgtct taagaaaaaa ctcagaaagc
     7141 tttcaagaaa atatcgaaat gcaaatggag attaaagcat ataatttatc gaaggatatt
     7201 aaagatgact tatataaaaa aatggaagat agtgagaaag tacacttaaa ggcggaagta
     7261 actacaattt taactttgtc tatatcttca atatttagct ttatatctct tgctgttgtg
     7321 atatttgtcg gcgtaaatct aattattaat aaagagataa attctctcta ccttatagga
     7381 tatttactag ctgctatgaa gataaaagac tctttagatg catctaaaga gggcttgatg
     7441 gaaatatttt atttatcgcc caaaatagaa agattaaaag aaattcaaaa tcaagattta
     7501 caagaaggcg atgactatag cttaaaaaaa tttgatattg atctaaaaga tgttgagttt
     7561 gcctacaata aagacgcaaa agttttaaat ggtgtaagtt ttaaagctaa gcagggagag
     7621 gtcactgctt tggtaggtgc aagtggctgc ggtaaaacaa ctatcttgaa acttatatca
     7681 agactttatg attatgacaa gggacaaatc ttaatcgatg gcaaagatat aaaggaaata
     7741 tcaacagaat ccctttttga taaggtgtct attgttttcc aagatgtggt tctctttaat
     7801 caaagcgtta tggaaaatat tagaatcggt aagcaagatg caagtgacga agaggttaaa
     7861 agagcagcaa aacttgcaaa ttgcacagat tttatagaaa aaatggataa aggtttcgat
     7921 acagttattg gtgaaaacgg agctgagcta tcaggaggag aaagacaaag attatcaata
     7981 gccagagcct tcttaaaaga tgcgccgata ttgatcttag atgagataac agcaagcctt
     8041 gatgttaaca acgagaaaaa gattcaagag tctttaaata atttagttaa agataaaact
     8101 gttgtaatca tttcacatag aatgaaatcc atagaaaatg cagacaagat agtagttctt
     8161 caaaacggaa gagtagaaag cgaaggtaag catgaagagc ttttacaaaa atcaaaaatt
     8221 tacaaaaatt taatagaaaa gacaaaaatg gcagaagaat ttatttatta ggaggactac
     8281 aatggataat aaaaaattaa aagtaaaaga tttagtaagc atcggtgttt ttggcgtaat
     8341 ttattttgcc ttcatgtttg gagttggtat gatgggcttg attccaatat tgttcttaat
     8401 atacccgaca gtattagcca tagttgcagg aactgttgtt atgttattta tggctaaggt
     8461 tcaaaagcca tgggcactat ttatatttgg tatgatatca ccacttgtga tgtttgcagc
     8521 tggtcatacc tacgtagttg tggttttatc acttatagta atgataatag cagaattaat
     8581 tagaaagatt ggtaattata attcatttaa atacaatatg ctttcttatg caatcttcag
     8641 cacatggata tgtagctctt taatgcaaat gcttttagca aaagaaaaat atatggagtg
     8701 gtctttgatg actatgggaa aagattatgt tgatgtatta gaaaagttaa taacttatcc
     8761 tcacatggct ttagtagcct taggtgcttt cttaggagga attcttggag catatatagg
     8821 caaggctcta ttgaaaaaac acttttcaaa tggattatat tgtgtgggat actttactcc
     8881 ttgcctaatt ttatggtgct atctgaatta aaccctatag ttaagatgtt tttgagtata
     8941 cctattgtta ttagaatgtt tattttacca tttatggcag caagctttat gataaagacc
     9001 tcggatgtag gcgcaataat ttcatcgatg gataagctta agatttcaaa gaatgtatcc
     9061 atacctattg cggttatgtt tagattcttc ccatctttta aggaggagaa gaaaaacatc
     9121 aaaatggcta tgagagtaag agggataaat tttaaaaacc cagtcaaata tcttgaatat
     9181 gtttctgtgc cactactcat tatatcatct aatatatcag atgacattgc aaaagcggca
     9241 gaaacaaagg caatagaaaa tccaattgcc aagaccagat acattcgcgt aaagatacag
     9301 ctaattgatt ttgtttatgt tttagcggtt gctggactta ttgtgggagg cttaatatgg
     9361 ttgaaataaa aaatttaagt cttgattatg gtgaagagca tatattagat gatatatcac
     9421 tatccatagc cgagggagag tgcgtgctat ttacaggaaa aagtggaaat ggtaagtcat
     9481 ctttaataaa ttcaatcaat ggactagctg taaggtatga taacgcaaag acaaagggcg
     9541 aaataattat tgatggtaag aatataaaaa atttggaact ttatcaaatc tcaatgcttg
     9601 tttcaactgt ttttcaaaat cctaagacat atttttttaa tgtcaatacg acattagaat
     9661 tattatttta tttggaaaat atcggtcttg caagagaaga gatggacagg cgtttgaagg
     9721 atatacttga gatattcccg ataaaaaatc ttttgaacag aaatatattt aatctatccg
     9781 gcggtgaaaa acaaattctt tgcattgcag cttcttatat agcaggtaca aagattatag
     9841 ttatggatga gccttcatcg aatttagata ttaaaagcat aagtgttttg gcaaagatgc
     9901 taaagatatt aaaagagaaa ggcataagca taattgttgc agagcataga atttattatt
     9961 tgatggacat agttgaccgt gtatttttaa tagataaagg aaagcttaaa aaaacttata
    10021 ctagaagtga atttttaaag ctagataaaa atgaattaaa tgctttaagt ttaagagata
    10081 aagaattaag taaattaaaa gttccttatt taaaagaagg tggagagtat cagataaaaa
    10141 atcttagtta caaatttact gatgatgagt gtttaagctt aaaagatatt tcgttcaagc
    10201 ttgggaaaat ttatggcata ataggatcca acggacgagg aaaatcaacg cttttaagat
    10261 gtttaatagg tcttgagaaa aaatcaaaag aagaaattta ttttaaggga gagaagctat
    10321 ctaaaaaaga aagactcaaa aactcttcac ttgttatgca agatgtaaat catcaattat
    10381 tcacagatga agtattcaac gagcttagat taggagtaaa gaattttgat gaagaaaagg
    10441 cgaaaatca
//
LOCUS       DAVFER010000063        10053 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1105170250
            SAMEA2167659-rid19724873.denovo.063, whole genome shotgun sequence.
ACCESSION   DAVFER010000063 DAVFER010000000
VERSION     DAVFER010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2167659
            Sequence Read Archive: ERR388902
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10053)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10053)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928716.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928716.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 04:07:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,118
            CDSs (total)                      :: 2,073
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 120
            CDSs (without protein)            :: 120
            Pseudo Genes (ambiguous residues) :: 0 of 120
            Pseudo Genes (frameshifted)       :: 67 of 120
            Pseudo Genes (incomplete)         :: 47 of 120
            Pseudo Genes (internal stop)      :: 34 of 120
            Pseudo Genes (multiple problems)  :: 23 of 120
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10053
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2167659-rid19724873.denovo.063"
                     /strain="1105170250"
                     /db_xref="taxon:1313"
     gene            complement(103..1806)
                     /gene="ilvD"
                     /locus_tag="VU534_001920"
     CDS             complement(103..1806)
                     /gene="ilvD"
                     /locus_tag="VU534_001920"
                     /EC_number="4.2.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxy-acid dehydratase"
                     /protein_id="HEU1514453.1"
                     /translation="MTELDKRHRSSIYDSMVKSPNRAMLRATGMTDKDFETSIVGVIS
                     TWAENTPCNIHLHDFGKLAKEGVKSAGAWPVQFGTITVADGIAMGTPGMRFSLTSRDI
                     IADSIEAAMSGHNVDAFVAIGGCDKNMPGSMIAIANMDIPAIFAYGGTIAPGNLDGKD
                     IDLVSVFEGIGKWNHGDMTAEDVKRLECNACPGPGGCGGMYTANTMATAIEVLGMSLP
                     GSSSHPAESADKKEDIEAAGRAVVKMLELGLKPSDILTREAFEDAITVTMALGGSTNA
                     TLHLLAIAHAANVDLSLEDFNTIQERVPHLADLKPSGQYVFQDLYEVGGVPAVMKYLL
                     ANGFLHGDRITCTGKTVAENLADFADLTPGQKVIMPLENPKRADGPLIILNGNLAPDG
                     AVAKVSGVKVRRHVGPAKVFDSEEDAIQAVLTDEIVDGDVVVVRFVGPKGGPGMPEML
                     SLSSMIVGKGQGDKVALLTDGRFSGGTYGLVVGHIAPEAQDGGPIAYLRTGDIVTVDQ
                     DTKEISMAVSEEELEKRKAETTLPPLYSRGVLGKYAHIVSSASRGAVTDFWNMDKSGK
                     K"
     gene            complement(2039..2971)
                     /locus_tag="VU534_001921"
     CDS             complement(2039..2971)
                     /locus_tag="VU534_001921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase family protein"
                     /protein_id="HEU1514454.1"
                     /translation="MMRSTKELRHVYRDFLLEANQSDSDIVVLEADLSSSMATNNLEK
                     DFGDRYVNVGIMEAEMVGLAAGLSIQGFRPYLHTFGPFASRRVFDQLFISLGYAQLDA
                     TVIGSDAGVTAEMNGGTHMPFEEIGLLRLIPKSIIFEATDDIQFREILNQTLDLKGLK
                     YIRTIRKAPVPVYQGGEDFSKGYIELRHGEDLVIVASGIMVAPSIRVADELSKLGYSV
                     GVIDLFRIKPIPEQIKTMLSGKTIFTVENHNQIGGIGSALCELFSDDGITKIHRMGVQ
                     ERFGQVGKMDYLLNEYGLSESNIKEKVLEIYNAR"
     gene            complement(2968..3825)
                     /locus_tag="VU534_001922"
     CDS             complement(2968..3825)
                     /locus_tag="VU534_001922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HEU1514455.1"
                     /translation="MILSKNREDGLRKFATNIRLNTLRTLNHLGFGHYGGSLSIVEVL
                     AVLYGEIMPMTPEIFAARDRDYFILSKGHGGPALYSTLYLNGFFDKEFLYSLNTNGTK
                     LPSHPDRNLTPGIDMTTGSLGQGISVATGLAYGQRIRKSPFYTYAIVGDGELNEGQCW
                     EAIQFASHQQLSNLIVFVDDNKKQLDGFTKDICNPGDFVEKFSAFGFESIRVKGSDIR
                     EIYEGIVQLKQSNNSSPKCIVLDTIKGQGVQELEEMKSNHHLRPTVEEKQMLTSVVER
                     LSQELEETE"
     gene            complement(3829..5175)
                     /locus_tag="VU534_001923"
     CDS             complement(3829..5175)
                     /locus_tag="VU534_001923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000975284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HEU1514456.1"
                     /translation="MMKFILDIVSTPAILVALIAILGLVLQKKKLPDIIKGGIKTFVG
                     FLVVSGGAGIVQNSLNPFGTMFEHAFHLSGVVPNNEAIVAVALTTYGSATAMIMFAGM
                     VFNILIARFTRFKYIFLTGHHTLYMACMIAVILSVAGFTSLPLILLGGLALGIIMSIS
                     PAFVQKYMVQLTGNDKVALGHFSSLGYWLSGFTGSLIGDKSKSTEDIKFPKSLAFLRD
                     STVSITLSMAVIYIIVAIFAGSEYIEKEISSGTSGLVYALQLAGQFAAGVFVILAGVR
                     LILGEIVPAFKGISERLVPNSKPALDCPIVYTYAPNAVLIGFISSFVGGLVSMVIMIA
                     SGTVVILPGVVPHFFCGATAGVIGNASGGVRGATIGAFLQGILISFLPVFLMPVLGGL
                     GFQGSTFSDADFGLSGIILGMLNQFGSQAGIVIGLVLILAVMFGVSFIKKPSATEE"
     gene            complement(5188..5472)
                     /locus_tag="VU534_001924"
     CDS             complement(5188..5472)
                     /locus_tag="VU534_001924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008089859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEU1514457.1"
                     /translation="MLKIGTACGSGLGSSFMVQMNIESVLSDLNVSDVEVEHYDLGGA
                     DPNAADIWIVGRDLADSASHLGDVRILNSIIDMDELRELITKLCEEKGLI"
     gene            complement(5476..7506)
                     /locus_tag="VU534_001925"
     CDS             complement(5476..7506)
                     /locus_tag="VU534_001925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000460919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HEU1514458.1"
                     /translation="MFDYRALVILMTLMDHCELSLYELSVKVSLPIKEVKEGIDYLVP
                     YLANKGIVLDKKQGRYSLSNRTKQSLTDIIKSDELVLPKSTRLALIYLYTFCRLDFIS
                     NSHYQDFLKVSKNTTLSDIQSLRKIMLDNDLELGYSRAKGYTLHGSEWNKHRLAFQMV
                     SELLESSIGIWGLDYVLSSWGYSLTYDLIDQVVKDYYEKLQLVPIVNQLKVYLFGLVF
                     ILCRYQRDVERVCLSETLVSPVIQDITTILLDTVVDLGIIDTVFSEDDYRYITVLLSS
                     CFEGEVDVAPVYFNQLTEAIISRMEDISLLHFKQREGLRENLRRHLIPAYYRLKFGLP
                     SSNEYVLHVKEHYPDLFELVKDSLMPLMDAIDNPIPDSETAYFVIHFGGYLKKADTLP
                     QKWYKAAIICPNGVSSSLMLKENLLALFPQIEFIGTSKIDDLQVKASSDYDMVFSTIK
                     VETEKPNYLVSVMMTEEQAIQLVELVLKDFPNLEYGDFEIEQILNIVKRYGIITQELE
                     LRLALKNYLYQKNDRKEIVPVLEQLITKETYQVSSQKLGWKEAIRLAAKPLLDQDKIT
                     ENYPEAMIQKVEEFGPFINLGKGVAIPHARPDEGVNEIGMSMLVLEEPIYLLDNPEQE
                     VRLLICIAAIDNESHLKALSHLTTILRDKNHVQTLISSKNYDDIKMIIKQED"
     gene            7698..8705
                     /locus_tag="VU534_001926"
     CDS             7698..8705
                     /locus_tag="VU534_001926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HEU1514459.1"
                     /translation="MTEKLINSKPNGVFALILIELTIVLGIFIFIMGVGSENIFGIII
                     GPLLIVIAGLAHAGLKVVKPQEALVLTLFGNYTGTIKEPGFYFVNPFSVAVNPANHTR
                     LGQSGDVSTKSPFLGAKSSNDNDVNLEIGKKQISLKVMTLSNSRQKINDCLGNPVEIG
                     IAVTWRVVDTAKAVFNVDNYKEYLSLQCDSALRNIVRIYPYDVSPNVDTTGDGQADEG
                     SLRGSSEIVANRIREEIQSRVEDAGLEILEARITYLAYAPEIAAVMLQRQQASAIIDA
                     RKMIVDGAVGMVEMALERLNEGELVELDEERKAAMVSNLLVVLCGNHDAQPIVNTGSL
                     Y"
     gene            8708..8908
                     /locus_tag="VU534_001927"
     CDS             8708..8908
                     /locus_tag="VU534_001927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HEU1514460.1"
                     /translation="MAEAKKKQIPLRLSTKLYAALASWAEDDFRSVNGQIEYLLTECV
                     KQRKKDGKYVSETIDEPFEIDI"
     gene            9060..9242
                     /gene="rpmF"
                     /locus_tag="VU534_001928"
     CDS             9060..9242
                     /gene="rpmF"
                     /locus_tag="VU534_001928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HEU1514461.1"
                     /translation="MAVPARRTSKAKKNKRRTHYKVTAPSVNFDETTGDYSRSHRVSL
                     KGYYKGRKITKAASAE"
     gene            9258..9407
                     /gene="rpmG"
                     /locus_tag="VU534_001929"
     CDS             9258..9407
                     /gene="rpmG"
                     /locus_tag="VU534_001929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001265622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEU1514462.1"
                     /translation="MRVNITLEHKESGERLYLTSKNKRNTPDRLQLKKYSPKLRKHVV
                     FTEVK"
     gene            complement(9899..>10053)
                     /locus_tag="VU534_001930"
     CDS             complement(9899..>10053)
                     /locus_tag="VU534_001930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000753868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HEU1514463.1"
                     /translation="WYYLNESGSMATGWVTVSGKWYYTYNSGDLLVNTTTPDGYRVNA
                     NGEWVG"
BASE COUNT         3260 a         2134 c         1627 g         3032 t
ORIGIN      
        1 caaaacactg ttttgaggtt gtggatagaa ctgacgaagt cagtaaccat acctacggca
       61 aggcgacgtt gacgtgattt gaagagattt tcgagtatga gtttattttt tacctgactt
      121 gtccatattc cagaagtctg tcacggctcc gcgtgaagca gatgatacga tgtgggcata
      181 tttaccgagg acaccacggc tgtaaagtgg tggcaaggtt gtttctgcct tgcgtttttc
      241 aagttcttct tcggatacgg ccatagaaat ttctttggta tcttggtcaa ccgtaacgat
      301 atcgccggta cggagatagg caattggtcc accatcctga gcttcaggag cgatatgtcc
      361 aacaaccaga ccataagtac caccagagaa acgtccgtcc gtcaagaggg ccaccttatc
      421 tccctgacct ttaccaacaa tcattgaaga aagtgatagc atctcaggca taccaggacc
      481 acctttaggt ccaacaaaac gaacaacgac tacatcgcca tcaacgattt catctgtcag
      541 aacggcctga atcgcatctt cttctgagtc aaagacctta gctggcccaa cgtgacgacg
      601 cactttaaca cctgatacct tggcaactgc accgtcagga gcaaggttcc cgttcaagat
      661 gataagcgga ccatccgcac gttttggatt ttcaagtggc atgataactt tttggcctgg
      721 agtcaagtct gcaaagtcag ccaagttttc agctacagtc ttaccagtac atgtgatgcg
      781 atctccgtga aggaaaccat ttgccaacaa atacttcata accgcaggga caccaccgac
      841 ttcgtagagg tcttggaaga catactgacc agatggtttc aagtcggcca agtgaggcac
      901 acgttcttga atcgtattga agtcctcaag tgacaagtca acatttgcgg catgggcaat
      961 ggcgagcaag tgaagagtgg cgtttgtaga accaccgaga gccatcgtta cagtgatagc
     1021 atcttcaaag gcttcacgag tcaagatatc tgatggtttg agaccaagtt ccaacatctt
     1081 aacaacagca cgtcctgctg cttcgatatc ttctttctta tcagctgatt cagctgggtg
     1141 agaggatgac cctggcaaac tcatccctag aacttcgata gcagttgcca tggtattagc
     1201 agtatacata ccaccacaac caccagggcc agggcaggca ttacattcaa gacgtttcac
     1261 gtcctcagct gtcatgtcac cgtggttcca ttttccgata ccttcaaaga cagaaaccaa
     1321 gtcgatatct ttaccatcaa gatttcccgg tgcaatagtt ccaccatagg cgaaaatagc
     1381 tgggatatcc atattagcaa tagcaatcat agatccaggc atgttcttgt cacagccacc
     1441 gatagcgacg aaggcatcca cgttgtgacc actcatagcc gcctcgatgg agtccgcgat
     1501 gatgtcacga gatgttagag agaaacgcat accaggcgtt cccatagcga tcccgtccgc
     1561 tacggtaatg gttccaaact gtacaggcca agcgcctgca gatttgacac cttctttagc
     1621 cagtttcccg aaatcatgca agtgaatgtt acatggtgta ttttccgccc aagtcgaaat
     1681 cactcccaca atcgatgttt caaagtcctt atctgtcata ccagtcgcac gaagcatagc
     1741 acggttaggt gatttaacca tgctgtcata aatgctactg cggtgacgtt tatctaattc
     1801 agtcatctta tccctcccat ttcagttttt actattatag cacaattttc gcatgaagaa
     1861 cagaataaaa ttcttgaatt ttcagaaaat tctatacaca tgtgaaatat ttaaaattaa
     1921 aaacaacaaa gcggattagt gcactttctg atgaccagaa tatgcttttt aatccgcttt
     1981 ctttaaataa cgtactgtaa tttttacaga aattctttca aataagtgta tttaacatct
     2041 atcttgcatt ataaatttct agaaccttct cttttatatt cgattcactc aaaccatact
     2101 cattaagaag ataatccatt ttccctactt gaccgaatct ttcttgaaca cccatccgat
     2161 gaatttttgt tattccatca tcagagaata attcacataa agcactgcca attccaccta
     2221 tctgattgtg gttttctaca gtaaatatag tttttccact taacattgtt tttatctgtt
     2281 ctggtatcgg tttgattcta aataaatcta tcacacctac tgaataacct aatttagaca
     2341 gttcatctgc aactcgaata cttggagcaa ccattatgcc agaagcaacg attacaagat
     2401 cttcaccatg ccttaactca atgtagcctt tagaaaaatc ttctccacct tgatacacag
     2461 gaactggagc ttttctaatt gttcgaatat attttagtcc ttttaagtct aatgtctggt
     2521 tcaatatttc acgaaattgg atatcatcag ttgcttcgaa aatgattgat ttaggaatta
     2581 aacgtaacaa tccaatttct tcaaatggca tatgtgttcc accattcatc tctgccgtta
     2641 ctcctgcatc tgatccaatc acagtggcat ccaattgtgc gtatccaaga gaaataaata
     2701 attgatcaaa tactcttcgt gaagcaaaag gaccaaatgt atgaagataa ggtctaaacc
     2761 cctgaataga caagcctgct gcaaggccga ccatttctgc ttccataatc ccaacattca
     2821 cataacggtc tccaaagtcc ttttcaagat tattagtagc catcgaactt gacaaatcgg
     2881 cttctaagac tactatatca gaatcacttt gattagcctc taaaaggaag tctctatata
     2941 catgccgtaa ttctttcgta cttctcatca ttctgtttcc tccaattcct gacttaatct
     3001 ttctacaact gaagttaaca tttgtttctc ctctacagta gggcgaagat gatgattgga
     3061 tttcatttct tccagctctt gaaccccttg acctttaata gtatctaata caatgcactt
     3121 aggtgatgaa ttatttgact gttttaattg gacaatccct tcataaattt ctctaatatc
     3181 tgaacccttg accctaatgg attcaaatcc aaatgctgaa aatttttcta cgaaatcacc
     3241 tggattacaa atatcctttg taaaaccatc taattgtttt ttgttatcat caacaaatac
     3301 aattaagttg gataactgtt gatgagaagc aaactgtata gcctcccaac attgtccctc
     3361 atttaactca ccatctccaa caatagcgta agtataaaag ggactctttc ttattctctg
     3421 accatatgca agtccagttg caacactaat tccttgtcct aaagagcccg ttgtcatatc
     3481 tatgcctggc gttagatttc tatcaggatg agacggtaat ttggttccat ttgtatttaa
     3541 agaatataag aattctttgt caaagaaacc attcaaatag agtgtactgt atagagctgg
     3601 tcctccgtga ccttttgata atatgaaata atctctatct cgtgctgcaa atatttctgg
     3661 agtcattggc attatttcac cataaagcac cgctaaaact tctacgatag acagacttcc
     3721 tccgtaatgt ccgaatccaa gatgattcaa tgttctaaga gtatttaatc ggatgttagt
     3781 cgcaaatttt cttaacccat cttctctatt tttacttaaa atcatccctt attcctccgt
     3841 tgcagatggc tttttaataa aggatactcc aaacataact gctagaataa gaacaagacc
     3901 aatcacaatg cctgcttgtg agccaaattg atttaacatt cctaaaataa ttcctgatag
     3961 accaaaatct gcatctgaga aagttgatcc ttggaaacca agtcctccca aaactggcat
     4021 taaaaagact ggaagaaaac tgattaaaat accttgtaaa aatgctccaa tagtggctcc
     4081 acgaacacca ccagatgcat tcccaatgac acctgcagtc gctccacaga agaaatgagg
     4141 cacaacacct ggtaagataa caaccgttcc tgaagcaatc ataattacca tacttactaa
     4201 accaccaaca aaactagaga taaatccaat tagaactgca ttgggtgcat aagtataaac
     4261 aatcggacaa tccaaagcag gttttgaatt aggtacaaga cgctctgaaa tacctttaaa
     4321 ggctggaaca atttcgccca aaataaggcg aacacctgct aaaataacaa atacccctgc
     4381 tgcaaattga cctgctaatt gtaaagcata aactagacca cttgtaccac tactgatttc
     4441 tttttctata tattctgacc ctgcaaagat agctacaata atgtaaataa ctgccatgga
     4501 taaagtaata ctaacagtac tatcacgtaa aaaagctaaa ctctttggaa atttaatgtc
     4561 ctctgttgat tttgatttgt caccgataag gctaccagta aaaccactca accaatatcc
     4621 caaagaactg aaatgaccta aagctacctt gtcatttcca gttaattgaa ccatatattt
     4681 ttgcacaaat gctggggaaa tactcataat aataccgagt gctaatcctc ctagtaagat
     4741 gagaggcaag ctagtaaagc cagcaactga taaaatgacc gcaatcatac atgccatata
     4801 tagagtgtgg tgccctgtta aaaaaatata tttaaatcga gtaaaacgag cgattaagat
     4861 attgaacacc atgcctgcaa acataatcat tgcagtagct gagccatatg ttgttaaagc
     4921 tacagctaca attgcttcat tattcggcac aacgccagat aaatgaaaag catgctcaaa
     4981 catggtacca aatggattta aagaattttg tacaattcct gcaccaccag atacaactaa
     5041 gaaaccaaca aaggtcttaa ttccaccttt aataatatca ggtaatttct tcttctgaag
     5101 aactaatcct aagattgcaa ttaaagctac taaaatagct ggtgtactaa caatatccaa
     5161 tatgaacttc atcatgacgc tagcctccta tataagtcct ttttcttcac aaagtttagt
     5221 aattaattct cgtagttcat ccatatcaat aatactattt aagatacgaa catctccaag
     5281 atgactagct gaatcagcta gatcacgacc aacaatccaa atatcagctg catttggatc
     5341 tgctccacct aaatcataat gttcaacttc tacatccgaa acattcaaat cactcaatac
     5401 agattcaata ttcatctgta ccataaaact tgaacctaat cctgaaccac aagctgtacc
     5461 aatttttaac attatctaat cctcctgttt aattatcatt ttaatgtcat catagttttt
     5521 tgatgatatt aaagtttgaa catgattttt atctcttaaa attgttgtta aatgtgacaa
     5581 agcctttaaa tgactctcat tatcaatggc tgcaatacaa atcaacaatc ttacctcttg
     5641 ttctggatta tccaataaat aaatcggttc ttccaaaact aacattgaca ttcctatttc
     5701 attcacacct tcatctggcc gagcgtgagg aattgctact cccttcccta aattaataaa
     5761 aggtccaaac tcttctactt tttgaatcat tgcctcaggg tagttctcag ttatcttatc
     5821 ttgatccaaa agcggtttag ctgctaaacg aatcgcctcc ttccatccta atttttgcga
     5881 actaacctga taggtttctt tggtaataag ttgttctagc actggtacaa tttcctttct
     5941 atcatttttt tggtaaagat aattctttaa cgccaatctt aattccaatt cttgtgtaat
     6001 aattccatat cttttgacaa tattcaggat ttgttcaatc tcaaaatctc catactctaa
     6061 attcggaaaa tcttttaaca ctagttctac tagttgtatt gcttgctctt cagtcatcat
     6121 aaccgaaact agataatttg gcttttctgt ctccaccttt atggtagaaa aaaccatatc
     6181 atagtcacta ctagctttca cctgtaaatc atcaatcttt gaggttccta taaactcaat
     6241 ttgaggaaat aatgctaata gattctcttt taacatcaat gaagaactaa caccattagg
     6301 acaaatgatt gctgctttat accatttttg aggcaaagta tctgctttct ttaaataacc
     6361 tccgaaatgg ataacaaaat atgctgtttc actatcaggt atgggattgt caatagcgtc
     6421 catcaagggc atcaaagaat ctttgactaa ttcaaataaa tcaggataat gttctttaac
     6481 atgcaataca tattcatttg aactaggtag gccgaacttt aatctatagt aagccggtat
     6541 aaggtggcgg cgaagatttt ctctcaatcc ttccctttgt ttaaaatgta acaaagaaat
     6601 atcttccatt ctacttataa tagcctctgt taattgatta aagtaaaccg gagcaacatc
     6661 tacttcacct tcaaagcaac ttgataataa aacggtgata tagcgataat catcctcaga
     6721 aaacaccgta tctataattc ccaaatcaac cactgtatcc aataaaatag tggttatatc
     6781 ttgaataaca ggagatacta atgtctctga aagacatact ctttcaacat ccctttgata
     6841 cctacacaga atgaatacta aaccgaaaag gtaaactttt aattgattaa caataggtac
     6901 tagctgtagc ttctcataat aatctttaac tacctgatca atcaaatcat aagttaatga
     6961 atacccccaa ctggataaaa cataatccaa accccaaatc cctatggagg attccagcaa
     7021 ctcactaacc atttgaaaag ctaagcggtg cttattccac tctgaaccgt gtaaagtata
     7081 accttttgct ctactgtacc ctagctccaa atcattatct aacataatct ttcttaatga
     7141 ttgaatatca gataaggttg tattcttact tactttcaaa aagtcttggt aatgactatt
     7201 cgatataaaa tctaatcggc aaaaagtgta aagatagatt aaagctaagc gagtcgactt
     7261 tggtaaaacc aattcatccg acttaataat atctgtcaaa gactgcttcg tacgatttga
     7321 taaactatag cgaccttgct ttttatccag cactatccct ttattagcta gataaggcac
     7381 taaataatct attccttctt tgacttcctt tataggtaag ctcaccttaa cagataattc
     7441 atataatgat agctcacaat gatccatcaa agtcatcaaa ataactagtg ctctataatc
     7501 aaacatttct cttcctttct aactacaatt atagtgtaaa aattataaga ataaaagagt
     7561 atttgagcac aatataatct caccttttaa aagaaattat tgggctgaaa gtttttagtg
     7621 attatttttc aactttctat tgactttata aattaaagtg atatcattta gatatcaaat
     7681 aacaggaggt cattcttatg actgaaaaac taatcaattc aaaaccaaat ggtgtattcg
     7741 cattgattct cattgagttg acaatcgtac ttggtatctt tatatttata atgggggttg
     7801 gttcggaaaa catttttgga attattatcg gacctttact aatcgtaatt gcaggtctag
     7861 ctcatgctgg tttaaaagtt gtcaaacctc aagaagctct ggttctgaca ctctttggta
     7921 actatacagg taccatcaaa gaacctggct tttactttgt caatcccttc agcgtagcag
     7981 tcaaccctgc aaaccacact cgacttggac aaagtggtga tgttagcaca aaatctcctt
     8041 ttttaggagc taaatcatca aatgacaatg atgtaaatct tgaaattggc aagaaacaga
     8101 tttccctcaa agtcatgacc ttgagcaatt ctcgtcaaaa aatcaatgat tgcttaggaa
     8161 accctgtaga aatcggtatc gcggtaactt ggagagttgt cgataccgct aaggcagtct
     8221 tcaacgttga taactacaaa gaatatcttt cattgcaatg tgatagcgcc ctccgtaata
     8281 ttgtccgcat ctatccttac gatgtgtctc ctaatgtgga tactacgggt gatgggcaag
     8341 cagatgaagg tagtctccgt ggctctagcg aaattgttgc taaccgtatt cgtgaagaaa
     8401 tccaaagtcg tgttgaggat gctggcttgg aaatccttga agcacgtatc acttacctag
     8461 cttatgctcc agaaattgct gccgttatgc ttcaacgcca acaagcatct gccattattg
     8521 atgcacggaa gatgattgta gatggtgctg taggaatggt tgaaatggca ctagaacggc
     8581 tcaatgaagg ggaattggta gaacttgacg aagaacgaaa agctgccatg gtttcaaatc
     8641 tccttgtcgt tctttgtggc aatcatgatg cacaaccaat tgtcaacaca ggaagccttt
     8701 actaaagatg gctgaagcta aaaaaaagca gatccccctt cgactctcaa caaagttata
     8761 cgctgcactc gcatcatggg cagaagacga ctttcgttca gtcaatgggc aaatcgaata
     8821 tctcctcaca gagtgtgtca agcaacggaa gaaagacgga aaatacgtat cagaaaccat
     8881 tgacgaacca tttgagattg atatttaaca ccttctcctg tctgccgtgt cggataggag
     8941 aattttttca tctttttttg tcaagtaact ttactttaca aaaaaaatgt gttatcctag
     9001 tatggttgat gaaaatcagt agattgaatc gaatataaat acctaaagga gaaatcaaaa
     9061 tggcagtacc tgcacgtcgc acttcaaaag cgaagaaaaa caaacgtcgt acacactaca
     9121 aagtaacagc tccatctgta aactttgacg aaactactgg agattactca cgttctcacc
     9181 gtgtatcact taaaggatac tacaaaggac gtaaaatcac taaagctgca tcagctgaat
     9241 aatagaaggg agataccatg cgcgtaaata ttacacttga acacaaagaa tctggtgaac
     9301 gcttgtacct tacttctaaa aacaaacgta acactccaga ccgccttcaa ttgaagaaat
     9361 actcaccaaa acttcgcaaa cacgttgtgt ttacagaggt taaataagca ttcaatacga
     9421 atcaatacag aagaaaaacg cttgatcagc gttttttctt tttgttaatt tcactacatt
     9481 gtaagggaaa tcattcgaat gactacattt ttcactacct tttttgaaat aagaatacgg
     9541 attcggacaa ttaaaagcaa gaggaactca aatgtaagtt ggggttcctt ttttgtatat
     9601 ttttcaaata acgcctctac actatttgta gcaaattcac caactacagt tgtatcttag
     9661 ttaaaataag ttagaatatg taagtgagta ccagatatac caagacatcg tcaccatcta
     9721 aggtatattc aaaatacaaa agttgaccaa ctagatttct gaatatcctt atatatccat
     9781 tcttaaaatt ggtttaaata gcgtagtctt ttaaactagt tttgagaatc caaaaaatct
     9841 tcctacatat gtaagaagat tttttagttc agaatgatta gatttagcta atggatacct
     9901 atcctaccca ctcaccgtta gcattgactc gatagccatc gggtgtagtc gtgtttacta
     9961 ataaatctcc tgaattatag gtatagtacc atttaccaga aactgtaacc caaccagtag
    10021 ccattgaacc tgattcattt aagtaatacc ata
//
LOCUS       DAVFER010000064         9839 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1105170250
            SAMEA2167659-rid19724873.denovo.064, whole genome shotgun sequence.
ACCESSION   DAVFER010000064 DAVFER010000000
VERSION     DAVFER010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2167659
            Sequence Read Archive: ERR388902
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9839)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9839)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928716.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928716.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 04:07:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,118
            CDSs (total)                      :: 2,073
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 120
            CDSs (without protein)            :: 120
            Pseudo Genes (ambiguous residues) :: 0 of 120
            Pseudo Genes (frameshifted)       :: 67 of 120
            Pseudo Genes (incomplete)         :: 47 of 120
            Pseudo Genes (internal stop)      :: 34 of 120
            Pseudo Genes (multiple problems)  :: 23 of 120
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9839
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2167659-rid19724873.denovo.064"
                     /strain="1105170250"
                     /db_xref="taxon:1313"
     gene            306..401
                     /locus_tag="VU534_001931"
                     /pseudo
     CDS             306..401
                     /locus_tag="VU534_001931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(654..1274)
                     /locus_tag="VU534_001932"
     CDS             complement(654..1274)
                     /locus_tag="VU534_001932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEU1514464.1"
                     /translation="MKLYFVRHGRTLWNQEGRFQGASGDSPLLPESIETLKRLGQYLK
                     EIPFDQIYSSDLPRAVKSAEIIQSQLYTPCSLEIVPNLREWQLGKLEGLKIATLEAIY
                     PQQIQAFRSNLAQFDTRMFGAESLYSTTQRTIQFIKSLKDSPAERILIVGHGANLTAS
                     LRTLLGYKEPLLRKDGGLANASLTIIETHDFETFTPNTWNDTSYQS"
     gene            complement(1274..1756)
                     /locus_tag="VU534_001933"
     CDS             complement(1274..1756)
                     /locus_tag="VU534_001933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA deacylase"
                     /protein_id="HEU1514465.1"
                     /translation="MAKKVKIKKTLVEQILSKAAIPHQGIQINALEGELPQGYERDQI
                     FKTLALLGDKTGPIIGIVPITQHLSEKKLAKISGNKKVSMIPQKDLEKTTGYIHGANN
                     PVGIRQKHNYPIFIDKIALDLDQMIVSAGEVGHSIIVAPQDLASFVKADFVDILEDIK
                     "
     gene            complement(1756..2598)
                     /locus_tag="VU534_001934"
     CDS             complement(1756..2598)
                     /locus_tag="VU534_001934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HEU1514466.1"
                     /translation="MLSWLARVIKGIVIALGFILPGISGGVLAAILGIYERMIGFLAH
                     PFKDFKENVLYFIPVAIGMLLGIGLFSYPIEYLLENYQVFVLWSFAGAIIGTVPSLLK
                     ESTRESDRDKIDLAWLWTTFIISGLGLYALNFVVGTLSASFLNFVLAGALLALGVLVP
                     GLSPSNLLLILGLYAPMLTGFKTFDFLGTFFPIGIGAGATLIVFSKLIDYALNNYHSR
                     VYHFIIGIVLSSTLLILIPNAGNAESIQYTGLSLVGYVIIAFFFALGIWLGIWMSQLE
                     DKYK"
     gene            complement(2693..3493)
                     /locus_tag="VU534_001935"
     CDS             complement(2693..3493)
                     /locus_tag="VU534_001935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 25 protein"
                     /protein_id="HEU1514467.1"
                     /translation="MRKQIHPLILFSFFGIMMFILIINRPLNDSQSFKTKSNIAQIEA
                     QALKHLDKPIIDLSGWQRPEEINYDALSQNISGAIVRVHSGAQTTKENDASFINGIDK
                     AYKSHITELQKRNVPVAVYAYVAGKSVQEMEKAAEVFYNAASPYSPSYYWLDVEDKTM
                     SNMNEGVENFRAKLASLGAKNIGIYVGVYFMEEHSIDTGKFTSVWIPSYGSDSGFLES
                     SPKTDLDYDIHQYTSKGKIAGFDHDLDINVISPLKNKEETFRKLFLKP"
     gene            3637..5016
                     /gene="glmU"
                     /locus_tag="VU534_001936"
     CDS             3637..5016
                     /gene="glmU"
                     /locus_tag="VU534_001936"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HEU1514468.1"
                     /translation="MSNFAIILAAGKGTRMKSDLPKVLHKVAGISMLEHVFRSVGAIQ
                     PEKTVTVVGHKAELVEEVLAGQTEFVTQSEQLGTGHAVMMTEPILEGLSGHTLVIAGD
                     TPLITGESLKNLIDFHINHKNVATILTAETDNPFGYGRIVRNDNAEVLRIVEQKDATD
                     FEKQIKEINTGTYVFDNERLFEALKNINTNNAQGEYYITDVIGIFRETGEKVGAYTLK
                     DFDESLGVNDRVALATAESVMRRRINHKHMVNGVSFVNPEATYIDIDVEIASEVQIEA
                     NVTLKGQTKIGAETVLTNGTYVVDSTIGAGAVITNSMIEESSVADGVIVGPYAHIRPN
                     SSLGAQVHIGNFVEVKGSSIGENTKAGHLTYIGNCEVGSNVNFGAGTITVNYDGKNKY
                     KTVIGNNVFVGSNSTIIAPVELGDNSLVGAGSTITKDVPADAIAIGRGRQINKDEYAT
                     RLPHHPKNQ"
     gene            5026..5571
                     /locus_tag="VU534_001937"
     CDS             5026..5571
                     /locus_tag="VU534_001937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000393791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEU1514469.1"
                     /translation="MEFEEKTLSRKEIYQGPIFKLVQDQVELPEGKGTAQRDLIFHNG
                     AVCVLAVTDEQKLILVKQYRKAIEAVSYEIPAGKLEVGENTAPVAAALRELEEETAYT
                     GKLELLYDFYSAIGFCNEKLKLYLASDLTKVENPRPQDEDETLEVLEVSLEEAKELIQ
                     SGHICDAKTIMAVQYWELQKK"
     gene            5583..5897
                     /locus_tag="VU534_001938"
     CDS             5583..5897
                     /locus_tag="VU534_001938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="foldase"
                     /protein_id="HEU1514470.1"
                     /translation="MGKSLLTDEMIERANRGEKISGPPLLDDNEETKILPTSSSRFGY
                     ANPKDHGFSQETLKIQVEPSIHKSRRIENTKRNVFNSKLNKILFAVIFLLILLVLAMK
                     LL"
     gene            5914..6606
                     /locus_tag="VU534_001939"
     CDS             5914..6606
                     /locus_tag="VU534_001939"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HEU1514471.1"
                     /translation="MKIGIIAAMPEELAYLVQHLDNAQEQVVFGNTYHTGTIASHEVV
                     LVESGIGKVMSAMSVAILADHFQVDALINTGSAGAVAEGIAVGDVVIADKLAYHDVDV
                     TAFGYAYGQMAQQPLYFESDKTFVAQIQKSLSQLDQNWHLGLIATGDSFVAGNDKIEA
                     IKSHFPEVLAVEMEGAAIAQAAHALNLPVLVIRAMSDNANHEANIFFDEFIIEAGRRS
                     AQVLLTFLKALD"
     gene            6683..7174
                     /gene="rocS"
                     /locus_tag="VU534_001940"
     CDS             6683..7174
                     /gene="rocS"
                     /locus_tag="VU534_001940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000021242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein RocS"
                     /protein_id="HEU1514472.1"
                     /translation="MSIEMTVSEIAEVLGLSRQAINNRVKELPEEDTDKNDKGVTVVT
                     RSGLIKLEEIYKKTIFEDEPVSEDVKQRELMEILVDEKNAEILRLYEQLKAKDRQLSE
                     KDEQMRIKDRQIAEKDKQLDQQQQLTLQAMKDQENLKLELDQAKEEVQSTKKGFFARL
                     FGG"
     gene            7272..7862
                     /locus_tag="VU534_001941"
     CDS             7272..7862
                     /locus_tag="VU534_001941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exonuclease"
                     /protein_id="HEU1514473.1"
                     /translation="MERLEDYIAFDLEFNQHEGQTHLIQVSAVRFRDGREIDAYDSYV
                     HTSVPLKSFINGLTGITAETLKDAPPVEKVLEEFQEFVGSLLMIGYNAAKSDLPILAE
                     HGLDYSQQYKVDLYDEAFERRSSDLHGIANLKLQTVASFLGFQGQSHNSLEDARMTAR
                     VYESFLESDQARELLETESSLSNNPFGGLDLSQLFD"
     gene            7871..9634
                     /locus_tag="VU534_001942"
     CDS             7871..9634
                     /locus_tag="VU534_001942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphoryl diester phosphodiesterase
                     membrane domain-containing protein"
                     /protein_id="HEU1514474.1"
                     /translation="MKPEKPKKLGLKQIYLDLDKILFLFFLIFMIVEYLWVPFNSWLA
                     SFLLDQTGYLFISYNNVLAILTHSPLISLAFLALIVINLLVAYFQIGLLFIGARHLLY
                     NEKRRLIEYIRKVFHESFGFMKKLTCAKALFIFFYIAMLFPFIRKMLKIYYLNKIVIP
                     EFIQAYLEDRYWMWWLSILLLSLIFLYVSVRLMFALPKIVYDQLTVREAVMFSLEKTK
                     KRVTFYAWNLFYILLKAHLLFYLPLIPLLLAQTLVDDITQRESLILGILNFVVIKNLY
                     YMALTYFLVKFVSFLTGKELDMLPRREKDHIVRWGVMTCASLFFALEGYIYLEAPMVH
                     LPQLISHRGVSNANGIQNTVESLETTAQLKPDLVETDVQETKDGQFVMMHDANLKNLA
                     GINKSPQDLNLEELKGIDIFENGYQTKISSFEDYLSRANELGQKLLIEIKTSKKDSPD
                     MMNRFLARYAAKLKIYGHQIQSLDYHVVEKVRQYDAELPVYFIMPYNSVFPKTRATGY
                     TMEYSTLDEYFVSKLWTTDQKLYVWTVNDSEAISKSLHLGVDGVITDDLEKVQREIEV
                     AQEDPEYTDLLLKKALEFFEF"
BASE COUNT         3051 a         1699 c         2087 g         3002 t
ORIGIN      
        1 aactttatca tcataagtta atttcataat aaaaacaccc caaaagttag attttttctg
       61 tctaactttt ggggtgtagt tcatgtacac ctgatatgat gcgttttata attttaaaga
      121 ctttttgacc agcctcattt ttttaacttg atactcagtg aaaagcaaag attaaactag
      181 gaagctagct gtaggctgct caaagaacag ctttgaggtt gtagataaaa cttgtgaggt
      241 caccaacata tataatgtga agctgacgtg gtttgaatag attttagaag agtatgagtc
      301 tggaagtttt aatggataat gcaagattcc atagaatggg taagctagag ttcttatgtg
      361 aagagtttgg gcataaactt ttaccttttc ctccctactc atcttagtat agaaaagtga
      421 atctgaaata gtacataact gcttctaaaa cattcttata aattgattta aattctcaaa
      481 tcatattatt cagttcttat ttcattttgt tctacaatcc tgttgagaag acacgtgttc
      541 atatcaaaaa ggtattggca agttgcaata cctttttacg aggctctgtt gtcttatttt
      601 tgtttcaact gactatatct cctatggttc tagttcagaa ggctaggcta taattatgat
      661 tgataagaag tatcattcca agtattggga gtgaatgttt caaaatcatg ggtttctata
      721 atggtcaggc tggcatttgc tagaccgcca tctttacgaa gaagtggttc tttatagcct
      781 aggagagtac gaagactggc agtaagattg gcgccgtgtc cgacaattag aatacgttca
      841 gctggactat cttttaatga tttgataaat tggatggtcc gttgagttgt actatagagg
      901 gattcggctc cgaacattcg agtgtcaaat tgagcaagat ttgaacgaaa agcctggatt
      961 tgttgcgggt aaatagcttc caaggttgca attttcaaac cttctaactt cccaagttgc
     1021 cattcacgga gattaggaac gatttctaaa gaacaggggg tatagagttg actttggata
     1081 atctcagcag atttgaccgc tcgaggtaaa tcacttgaat aaatctgatc aaaaggaatt
     1141 tccttgagat actgaccaag tcgttttagg gtttcaatgg attcaggaag aagaggagaa
     1201 tcaccactag caccttgaaa acgaccttct tggttccaga gggtacgacc gtggcggaca
     1261 aagtagagtt tcattacttg atgtcctcca aaatatctac aaagtctgcc tttacaaagc
     1321 tagccaagtc ttgtggcgcg acgataatgc tgtgtccgac ttcgcctgca gagacaatca
     1381 tttgatccaa atctagagca attttatcga taaaaatggg ataattgtgt ttctgacgaa
     1441 ttccgacagg attattggct ccatgaatgt aaccagttgt tttttctaag tccttttgtg
     1501 gaatcatgct cactttttta ttgccagaaa ttttagctag tttcttttca gacaagtgct
     1561 gagtgatagg gacaattccg ataatcggtc cggtcttgtc tcccaaaagc gccaaggttt
     1621 tgaaaatctg atctcgttca taaccttgag gaagctctcc ttctagggca ttgatttgaa
     1681 tcccctgatg agggatagct gctttagata ggatttgttc caccaatgtt tttttgattt
     1741 taactttttt tgccattatt tatatttatc ctccaattga ctcatccaaa taccaagcca
     1801 gattcccagc gcaaagaaga aggcgatgat gacataaccg acaagtgaaa gtcctgtgta
     1861 ttggatactt tcagcgtttc ctgcatttgg aattaagatc aaaagggtac ttgataggac
     1921 gataccgatg atgaaatgat agacgcgtga gtggtagttg tttaaggcat aatctatcaa
     1981 ttttgaaaaa acgatgagag ttgcacctgc accaattcca atcggaaaga aggttcccaa
     2041 gaaatcaaaa gttttaaaac cagtcaacat aggagcatag agtcccaaaa tcaaaagtaa
     2101 atttgatggg ctgaggccag gaaccaagac gccaagggcc aatagtgcgc ctgctaggac
     2161 gaagttaaga aagctggcgc ttaaggttcc aacgacaaaa tttaaggcat agagtcctaa
     2221 tccagaaatg ataaaggttg tccataacca agctaaatca atcttgtctc ggtcagattc
     2281 tcgagttgat tctttgagga ggctaggaac tgtaccgata atagctcccg caaagctcca
     2341 taatacaaaa acctgataat tttcaagcag gtattcaatc gggtaggaaa ataagccgat
     2401 tcccagaagc ataccgatgg caactggaat aaagtacaaa acattttctt taaagtcttt
     2461 aaagggatgg gccagaaagc caatcattcg ttcatagatt cctaagattg ctgctagaac
     2521 ccctccggaa attcccggta ggataaatcc aagagcaatt acaatccctt taataacgcg
     2581 tgctaaccat gagagcatat atttcctcca actatttcta tttcaaaaaa tccttactat
     2641 attgtatcac aatcagacac aaaaagaaaa agcaaatgat aaacaaatgc ttttaaggtt
     2701 ttaaaaaaag ttttcgaaag gtttcttctt tattttttaa gggagagata acgttgatat
     2761 ctaaatcgtg gtcaaagccg gcaatttttc ctttagatgt gtattggtga atatcataat
     2821 ctaaatcagt tttaggactg ctctccaaaa atcctgagtc tgagccgtag gacggaatcc
     2881 aaacagaggt aaacttgcct gtatcaatac tgtgttcttc catgaagtag acaccaacgt
     2941 agatgccgat gtttttagca cccagtgatg ctagttttgc tcgaaagttt tcgacacctt
     3001 cgttcatatt agacatggtt ttgtcttcca cgtcaagcca atagtaacta gggctgtaag
     3061 gagaggcagc attgtagaaa acttcggcag ccttttccat ttcttggaca ctttttccag
     3121 ctacataagc gtagacagca actgggacat tccgcttttg aagttcagtg atatgactct
     3181 tataggcctt gtctattcca ttgataaatg aagcatcatt ttcttttgtc gtttgagcac
     3241 cactgtgaac acgaacaata gcacctgaaa tattttgtga gagggcatcg tagttgattt
     3301 cctcaggacg ctgccagcca gagaggtcaa taatcggttt gtctaagtgt ttcaaagcct
     3361 gtgcttcaat ctgtgctata ttggattttg ttttaaacga ttggctgtca ttaagtgggc
     3421 gattgatgat taaaatgaac atcataatcc caaaaaaact aaataaaata agtggatgaa
     3481 tttgttttct catatcttat aattctaccc taaaaatcaa aaaaaatcaa aaaaatgggt
     3541 taaggaagag actttagagc attttttcat tcaagagtgc ggaatgattt gaaatatggt
     3601 ataataaaag ggaatttcta cagaaaagag aagattatgt caaattttgc cattatttta
     3661 gcagcgggta aagggactcg catgaaatct gatttgccaa aagttttgca caaggttgcg
     3721 ggtatttcta tgttggaaca tgttttccgt agtgtgggag ctatccaacc tgaaaagaca
     3781 gtaacagttg taggacacaa ggcagaattg gttgaggagg tcttggctgg acagacagaa
     3841 tttgtgactc aatctgaaca gttgggaact ggtcatgcag ttatgatgac agagcctatc
     3901 ttagaaggtt tgtcaggaca caccttggtc attgcaggag atactccttt aatcactggt
     3961 gaaagcttga aaaacttgat tgatttccat atcaatcata aaaatgtggc cactatcttg
     4021 actgctgaaa cggataatcc ttttggttat ggacgaattg ttcgtaatga caatgctgag
     4081 gttcttcgta ttgttgagca gaaggatgct acagattttg aaaagcaaat caaggaaatc
     4141 aacactggaa catacgtctt tgacaacgag cgtttgtttg aggctttgaa aaatatcaat
     4201 accaataacg ctcaaggcga atactatatt acagacgtca ttggtatttt ccgtgaaact
     4261 ggtgaaaaag ttggcgctta tactttgaaa gattttgatg aaagtcttgg ggtaaatgac
     4321 cgtgtggcgc ttgcgacagc tgagtcagtt atgcgtcgtc gcatcaatca taaacacatg
     4381 gtcaacggtg ttagctttgt caatccagaa gcaacttata tcgatattga tgttgagatt
     4441 gcttcggaag ttcaaatcga agccaatgtt accttgaaag ggcaaacgaa aattggtgct
     4501 gagactgttt tgacaaacgg tacttatgta gtggacagca ctatcggagc aggagcggtc
     4561 attaccaatt ctatgattga ggaaagtagt gttgcagacg gtgtgatagt cggtccttat
     4621 gctcacattc gtccaaattc aagtctgggt gcccaagttc atattggtaa ctttgttgag
     4681 gtgaaaggat cttcaatcgg tgagaatacc aaggctggtc atttgactta tatcggaaac
     4741 tgtgaagtgg gaagcaacgt taatttcggt gctggaacta ttacagtcaa ctatgacggc
     4801 aaaaacaaat acaagacagt cattggaaac aatgtctttg ttggttcaaa ttcaaccatt
     4861 attgcaccag tagaacttgg tgacaattcc ctcgttggtg ctggttcaac tattactaaa
     4921 gacgtgccag cagatgctat tgctattggt cgcggtcgtc agatcaataa agacgaatat
     4981 gcaacacgtc ttcctcatca tcctaagaac cagtaggagc ctatcatgga gtttgaagaa
     5041 aaaacgctta gccgaaaaga aatctatcaa ggaccaatat ttaaactggt ccaagatcag
     5101 gttgaattac cagaaggcaa gggaactgcc caacgggatt tgattttcca caatggggct
     5161 gtctgtgttt tagcagtaac ggatgaacaa aaacttatct tggtcaagca gtaccgcaaa
     5221 gctatcgagg ctgtctctta cgaaattcca gccggaaaat tggaagtagg agaaaacaca
     5281 gcccctgtgg cagctgccct tcgtgaatta gaggaagaaa cagcctatac agggaaatta
     5341 gaactcttgt acgattttta ttcagctatt ggcttttgta atgagaagtt aaaactatat
     5401 ttagcaagcg atttgacaaa agtggaaaat ccgcgtccgc aggatgagga tgaaaccttg
     5461 gaagtccttg aagtgagctt agaagaagcg aaagaattaa tccaatcagg tcatatctgt
     5521 gatgccaaga caattatggc tgttcagtat tgggagttgc agaaaaaata gaggaggtca
     5581 gtatgggtaa atctttatta acggatgaaa tgattgaaag agctaataga ggcgaaaaaa
     5641 tttcaggtcc tcctttgcta gatgataatg aggaaactaa gattttacca acctcttctt
     5701 cccgttttgg ttatgccaat cctaaggatc atggttttag ccaggaaacc ttgaagattc
     5761 aggtcgaacc atctattcat aaaagccgtc gtattgaaaa taccaagaga aatgtcttca
     5821 attctaagtt gaataaaatc ttatttgcgg tcatctttct cttgattttg cttgttttag
     5881 caatgaaact tttgtaatag aaaaggaatt gaaatgaaaa taggaattat tgctgctatg
     5941 ccagaagaac tggcttatct ggtccagcat ttagataatg cccaggagca agttgttttt
     6001 gggaatacct atcatacagg aaccattgct tctcatgaag tcgttcttgt agaaagtgga
     6061 attggtaagg tcatgtctgc tatgagtgtg gcgattttgg ctgatcattt ccaggtggat
     6121 gcccttatta atacgggttc agctggggca gtagcagaag gtatcgctgt tggggatgtc
     6181 gtgattgctg acaaattagc ctatcatgac gtggatgtca cagcttttgg ctatgcttat
     6241 ggacaaatgg cgcaacaacc gctttatttc gaatcagaca aaacctttgt tgctcaaatc
     6301 caaaagagtt tatctcaatt ggaccaaaac tggcatcttg gtttgattgc tacaggagat
     6361 agttttgttg caggaaatga caagatagaa gcgattaagt cccatttccc agaagtttta
     6421 gccgtggaga tggagggggc agctattgct caagcagcgc atgccctcaa tctcccagtc
     6481 ttagtcatcc gagctatgag tgacaatgcc aaccatgaag caaacatctt ttttgatgag
     6541 tttattatcg aagctggacg tcgctctgcc caagtcttgt tgaccttttt gaaggcttta
     6601 gattaagcgg aaatttgaca gtttttctag cttatgataa gatttaagta aagaaaagct
     6661 agaaaacgtt tcagaggata ttatgagtat tgaaatgacc gtcagtgaga ttgcagaggt
     6721 cttaggatta tctcgccaag caatcaataa ccgtgtcaaa gaattaccag aagaagacac
     6781 agataaaaat gacaaagggg taacagttgt taccagaagt ggcttgatta agctagaaga
     6841 aatctataaa aaaacgattt ttgaagatga gcctgtcagt gaagatgtca aacaacgtga
     6901 actgatggag attctagtgg atgagaagaa tgcagaaatt cttcgtcttt atgaacaatt
     6961 aaaagccaag gatcgtcagt tatcagaaaa agacgagcag atgcgtatca aagaccgtca
     7021 gattgctgag aaagacaaac aattagatca gcaacaacaa ttgacccttc aagccatgaa
     7081 ggatcaagaa aatcttaagc tagagctgga ccaagcaaaa gaagaagtcc aatccactaa
     7141 aaaaggcttt tttgctcgtt tatttggagg ataatcaagg agctgtttag gttaaatgct
     7201 aacctgatgg cttcttttgt ttgtgaatag tatagttgat tagaacagag acagtagagg
     7261 agaggtacag aatggaacga ttagaagatt acattgcttt tgatttagaa tttaatcagc
     7321 acgaaggaca aacacacttg attcaagtat cggcagtgcg ttttagagat ggtcgggaaa
     7381 tcgatgccta tgattcctat gttcatacca gcgtccctct aaaaagcttt atcaatggtt
     7441 tgaccgggat tacagctgag accttaaaag atgctcctcc agttgagaaa gtcttagaag
     7501 aattccaaga gtttgtgggt tctttgctga tgataggcta caatgctgct aaaagtgatt
     7561 tacctatttt agcagagcat ggtttagact atagccaaca gtacaaggtg gatttgtatg
     7621 atgaagcttt tgaacgtcgg agttcagatt tacatggtat tgccaatctc aaattgcaaa
     7681 ctgttgcctc atttcttgga tttcaaggtc agtctcataa tagtttagag gatgctcgga
     7741 tgacggcgcg tgtttacgaa tccttcttag agtcggatca agctagggaa ttgttagaga
     7801 cagaaagtag cttatcaaac aatccttttg gtggcttgga cttgtctcaa ttatttgact
     7861 aggagtgcct atgaaacctg aaaaacctaa aaaattgggt cttaaacaga tttacctcga
     7921 tcttgataaa atcctctttc tatttttctt gatttttatg atagtggagt atttgtgggt
     7981 accattcaat tcatggttgg ctagcttctt attagatcag acaggttatc tttttatttc
     8041 ctataacaat gtcttagcca tccttactca ttctccattg attagtctag cttttttagc
     8101 cttgattgta attaaccttc tggttgctta ttttcaaata ggactcctct ttattggtgc
     8161 tcgtcatctc ctctataatg aaaagcgaag gctaattgag tatatccgca aggttttcca
     8221 tgaaagtttt ggatttatga aaaagctaac ttgcgctaaa gccttgttta tctttttcta
     8281 tatagctatg ctgtttcctt ttatacggaa aatgctgaag atttattatc ttaataaaat
     8341 cgtcattcca gagtttatcc aagcttattt agaagataga tattggatgt ggtggctgag
     8401 catcctactt ctatctctta tctttctcta tgtctctgtc agattgatgt ttgcccttcc
     8461 gaagattgta tatgatcagc tgactgttcg agaagcagtg atgtttagct tggagaaaac
     8521 caagaagaga gttacttttt atgcttggaa tttattttac atcttgctca aagcacattt
     8581 attattttat cttcctttga ttcctttatt attggctcaa actttggtag atgatatcac
     8641 tcagagagag tctctgattc ttggtatttt gaattttgtc gtgattaaaa atctctatta
     8701 tatggctctg acttattttt tggttaaatt tgtttcattt ttgacaggaa aggagctgga
     8761 tatgcttcct aggagagaaa aagatcacat cgtgcgatgg ggtgtcatga cttgtgccag
     8821 tcttttcttt gccttagaag gttatattta tctggaggct cccatggttc atctacctca
     8881 acttatttct caccgagggg tttccaatgc aaatgggatt caaaatacag tagagtcctt
     8941 ggaaactaca gcacaactca aaccagactt ggtggagacg gacgtgcagg aaacaaaaga
     9001 tgggcagttt gtcatgatgc atgatgctaa cttgaaaaat ctagcaggta tcaataaaag
     9061 tcctcaagac ttaaacttgg aggagcttaa agggattgat atttttgaaa atggctacca
     9121 gactaaaatt tcaagctttg aagattatct cagtcgagcc aacgaacttg gtcaaaaatt
     9181 actaattgaa attaaaacca gtaaaaaaga tagtccagac atgatgaacc gctttttagc
     9241 ccgttatgct gcaaagctca agatttatgg acatcaaatc cagtctttag actaccatgt
     9301 tgtcgaaaaa gtaagacagt atgatgccga actaccagtt tatttcatca tgccctacaa
     9361 ttctgtcttt cctaaaacaa gagcgacagg atatactatg gagtactcaa ccttggatga
     9421 atattttgta agcaaactat ggacaacgga tcagaaactt tatgtctgga ctgtcaatga
     9481 ttcagaagct atcagcaaat ctcttcactt aggagtagat ggagtgatta cagatgattt
     9541 ggaaaaagtt cagcgggaaa tagaagtagc ccaagaagat ccagaatata cggatttgct
     9601 cttgaaaaaa gcattggaat tctttgaatt ttagtaataa aaaagaggaa cggttgttcc
     9661 tcccatgata ggtaagtatt cttgtgaatg cttgcttttt tgtggttgca atccgtttac
     9721 gagaattgtt tgtattgttc ttgtttcaat ttactttata gtgctttgaa gttggaatgc
     9781 tacactataa cttataaaat atagtaaaat gaaccaaaaa tagtacacaa tgtggtata
//
LOCUS       DAVFER010000065         9641 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1105170250
            SAMEA2167659-rid19724873.denovo.065, whole genome shotgun sequence.
ACCESSION   DAVFER010000065 DAVFER010000000
VERSION     DAVFER010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2167659
            Sequence Read Archive: ERR388902
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9641)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9641)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928716.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928716.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 04:07:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,118
            CDSs (total)                      :: 2,073
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 120
            CDSs (without protein)            :: 120
            Pseudo Genes (ambiguous residues) :: 0 of 120
            Pseudo Genes (frameshifted)       :: 67 of 120
            Pseudo Genes (incomplete)         :: 47 of 120
            Pseudo Genes (internal stop)      :: 34 of 120
            Pseudo Genes (multiple problems)  :: 23 of 120
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9641
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2167659-rid19724873.denovo.065"
                     /strain="1105170250"
                     /db_xref="taxon:1313"
     gene            complement(300..1280)
                     /gene="dusB"
                     /locus_tag="VU534_001943"
     CDS             complement(300..1280)
                     /gene="dusB"
                     /locus_tag="VU534_001943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HEU1514475.1"
                     /translation="MTNLNTPFMIGNIEIPNRTVLAPMAGVTNSAFRTIAKELGAGLV
                     VMEMVSDKGIQYNNEKTLHMLHIDEGENPVSIQLFGSDEDSLARAAEFIQENTKTDIV
                     DINMGCPVNKIVKNEAGAMWLKDPDKIYSIINKVQSVLDIPLTVKMRTGWADPSLAVE
                     NALAAEAAGVSALAMHGRTREQMYTGHADLETLYKVAQALTKIPFIANGDIRTVQEAK
                     QRIEEVGADAVMIGRAAMGNPYLFNQINHYFETGEILPDLTFEDKMKIAYEHLKRLIN
                     LKGENVAVREFRGLAPHYLRGTSGAAKLRGAISQASTLAEIETLLQLEKA"
     gene            complement(1267..2139)
                     /gene="hslO"
                     /locus_tag="VU534_001944"
     CDS             complement(1267..2139)
                     /gene="hslO"
                     /locus_tag="VU534_001944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000357853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HEU1514476.1"
                     /translation="MDKIIKTISESGAFRAFVLDSTETVRTAQEKHQTQASSTVALGR
                     TLIASQILAANEKGNTKLTVKVLGSSSLGAIITVADTKGNVKGYVQNPGVDIKKTATG
                     EVLVGPFVGNGQFLVITDYGTGNPYNSITPLISGEIGEDLAFYLTESQQTPSAVGLNV
                     LLDEEDKVKVAGGFLVQVLPGAKKEEIARFEKRIQEMPAISTLLESDDHIEALLKAIY
                     GDEAYKRLSEEEIRFQCDCSHERFMNALASLPSSDLQEMKEEDHGAEITCQFCQTTYN
                     FDEKDLEELIRDKS"
     gene            2304..3731
                     /locus_tag="VU534_001945"
     CDS             2304..3731
                     /locus_tag="VU534_001945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000280545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEU1514477.1"
                     /translation="MYLGDLMEKAECGQFSILSFLLQESQTTVKAVMEETGFSKATLT
                     KYVTLLNDKALDSGLELAIHSEDENLRLSIGAATKGRDIRSLFLESAVKYQILVYLLY
                     HQQFLAHQLAQELVISEATLGRHLAGLNQILSEFDLSIQNGRWRGPEHQIHYFYFCLF
                     RKVWSSQEWEGHMQKPERKQEIANLEEICGASLSAGQKLDLVLWAHISQQRLRVNACQ
                     FQVIEEKMRGYFDNIFYLRLLRKVPSFFAGQHIPLGVEDGEMMIFFSFLLSHRILPLH
                     TMEYILGFGGQLADLLTQLIQEMKKEELLGDYTEDHVTYELSQLCAQVYLYKGYILQD
                     RYKYQLENRHPYLLMEHDFKETAEEIFHALPAFQQGTDLDKKILWEWLQLIEYMAENG
                     GQHMRIGLDLTSGFLVFSRMAAILKRYLEYNRFITIEAYDPSRHYDLLVTNNPIHKKE
                     QTPVYYLKNDLDMEDLVAIRQLLFT"
     gene            3890..5398
                     /gene="glpK"
                     /locus_tag="VU534_001946"
     CDS             3890..5398
                     /gene="glpK"
                     /locus_tag="VU534_001946"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HEU1514478.1"
                     /translation="MSQEKYIMAIDQGTTSSRAIIFNKKGEKVSSSQKEFTQIFPQAG
                     WVEHNANEIWNSVQSVIAGAFIESGVKPNQIEAIGITNQRETTVVWDKKTGLPIYNAI
                     VWQSRQTAPLAEQLKSQGYVEKFHEKTGLIIDAYFSATKVRWILDHVEGAQERAEKGE
                     LLFGTIDTWLVWKLTDGAAHVTDYSNAARTMLYNIKELKWDDEILEILNIPKAILPEV
                     RSNSEIYGKTAPFHFYGGEVPISGMAGDQQAALFGQLAFEPGMVKNTYGTGSFIIMNT
                     GEEMQLSENNLLTTIGYGINGKVYYALEGSIFIAGSAIQWLRDGLRMVENSPESEKYA
                     RDSHNNDEVYVVPAFTGLGAPYWNQNARGSVFGLTRGTSKEDFIKATLQSIAYQVRDI
                     IDTMQVDTQTAIQVLKVDGGAAMNNFLMQFQADILGIDIARAKNLETTALGAAFLAGL
                     SVGYWKDLDELKLLNETGELFEPSMNESRKEQLYKGWKKAVKATQVFAEVDD"
     gene            5440..7266
                     /gene="glpO"
                     /locus_tag="VU534_001947"
     CDS             5440..7266
                     /gene="glpO"
                     /locus_tag="VU534_001947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glycerol-3-phosphate oxidase"
                     /protein_id="HEU1514479.1"
                     /translation="MEFSKKTRELSIKKMQERTLDLLIIGGGITGAGVALQAAASGLE
                     TGLIEMQDFAEGTSSRSTKLVHGGLRYLKQFDVEVVSDTVSERAVVQQIAPHIPKSDP
                     MLLPVYDEDGATFSLFRLKVAMDLYDLLAGVSNTPAANKVLSKDQVLERQPNLKKEGL
                     VGGGVYLDFRNNDARLVIENIKRANQDGALIANHVKAEGFLFDESGKITGVVARDLLT
                     DQVFEIKARLVINTTGPWSDKVRNLSNKGTQFSQMRPTKGVHLVVDSSKIKVSQPVYF
                     DTGLGDGRMVFVLPRENKTYFGTTDTDYTGDLEHPKVTQEDVDYLLGIVNNRFPESNI
                     TIDDIESSWAGLRPLIAGNSASDYNGGNNGTISDESFDNLIATVESYLSKEKTREDVE
                     SAVSKLESSTSEKHLDPSAVSRGSSLDRDDNGLLTLAGGKITDYRKMAEGAMERVVDI
                     LKAEFDRSFKLINSKTYPVSGGELNPANVDSEIEAFAQLGVSRGLDSKEAHYLANLYG
                     SNAPKVFALAHSLEQAPGLSLADTLSLHYAMRNELTLSPVDFLLRRTNHMLFMRDSLD
                     SIVEPILDEMGRFYDWTEEEKATYRADVEAALANNDLAELKN"
     gene            7336..8040
                     /locus_tag="VU534_001948"
     CDS             7336..8040
                     /locus_tag="VU534_001948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HEU1514480.1"
                     /translation="MMNELFGEFLGTLILILLGNGVVAGVVLPKTKSNSSGWIVITMG
                     WGIAVAVAVFVSGKLSPAYLNPAVTIGVALKGGLPWASVLPYILAQFAGAMLGQILVW
                     LQFKPHYEAEENAGNILATFSTGPAIKDTVSNLISEILGTFVLVLTIFALGLYDFQAG
                     IGTFAVGTLIVGIGLSLGGTTGYALNPARDLGPRIMHSILPIPNKGDGDWSYAWIPVV
                     GPVIGAALAVLVFSLF"
     gene            8337..8540
                     /locus_tag="VU534_001949"
     CDS             8337..8540
                     /locus_tag="VU534_001949"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1514481.1"
                     /translation="MPKWSNPDYVNELDPKIVDMLVEFHKSQGTLETPEAQAEIAQKR
                     EEIEQRRAELEGKKQELLNRLNK"
     gene            complement(8627..9214)
                     /locus_tag="VU534_001950"
     CDS             complement(8627..9214)
                     /locus_tag="VU534_001950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1514482.1"
                     /translation="MFVFADDSLSANSKVVSGEAQFENGSSVRFGDTQVNILSDEVLE
                     VVNPDGSVDTIERRADGVYINGAFYMAYQKNEIDLNISFRSYDPNVWNYVNTIHGNKQ
                     ANTFANFMTGAGISYMIGRIGALLGGPWGAIIGGAYFGIQAYQSYLDSQSPYPYYITS
                     TYIHVAQRKWKFITEYYRNSNYTGYVKTVTTYVNF"
BASE COUNT         2782 a         1915 c         2185 g         2759 t
ORIGIN      
        1 aggtgccctt gcagtcaaca caactgtaga tggctatgga gtcaatgcca atggtgaatg
       61 ggtaaactaa acctaatata actagttaat actgacttcc tgtaagaact ctttaaagta
      121 ttccctacaa ataccatatc ctttcagtag ataatatacc cttgtaggaa gtttagatta
      181 aaaaataact ctgtaatctc tagccggatt tatagcgcta gagactacgg agtttttttg
      241 atgaggaaag aatggcggca ttcaagaggc tctttaagag agttacgggt tttaaactat
      301 taagccttct ccaattgcaa gagggtttca atctctgcca gggtgctggc ttgcgaaatg
      361 gctccacgga gtttggcagc gccagatgtt ccacggagat agtgaggagc gagaccgcgg
      421 aattcacgaa ctgcgacgtt ttctcctttg aggttaatca atcgtttcaa gtgttcgtag
      481 gcgatcttca tcttgtcttc aaaggtcaaa tcaggtagga tttctcctgt ttcaaagtaa
      541 tggttgattt ggttgaagag gtaaggattt cccatggcag ctcggccaat catgactgcg
      601 tcagcaccaa cttcttcgat gcgttgcttg gcttcttgga cagtacggat atcaccgttg
      661 gcgatgaatg gaatcttggt tagagcttgg gcaaccttgt aaagggtctc aaggtctgcg
      721 tggccagtat acatttgttc acgggtacgg ccatgcatgg cgagggcaga aacacctgca
      781 gcttcagcag cgagagcatt ttctactgca agagatgggt ccgcccagcc ggtacgcatt
      841 ttgacagtaa gtgggatatc aaggacagac tggaccttgt tgatgatgga gtaaatcttg
      901 tctggatcct tgagccacat agcaccagct tcgttcttca cgattttgtt gacagggcag
      961 cccatgttga tatcgacgat atcggtcttg gtgttttctt ggatgaattc tgctgcgcgt
     1021 gctaggctgt cttcatcgct accaaaaagt tggatagaga cagggttttc gccctcatcg
     1081 atatgaagca tgtgcagggt tttttcgttg ttgtattgga ttcccttgtc agagaccatt
     1141 tccattacaa cgagtccagc tccgagctcc tttgcgatag tacgaaaggc tgagttggtc
     1201 acgccagcca taggcgctaa aacggtacga ttgggaatct caatattgcc aatcataaaa
     1261 ggtgtattaa gatttgtcac gaatgagttc ctccaggtcc ttttcatcaa agttgtaagt
     1321 agtttggcag aattgacaag tgatttctgc cccgtggtct tcctctttca tttcctgtaa
     1381 gtctgagctt ggaaggctgg caagagcgtt cataaagcgt tcatggctac agtcacattg
     1441 gaaacggatt tcttcttcag aaagacgctt gtaggcttcg tccccgtaga tagccttgag
     1501 gagggcttcg atatggtcgt cgctttcgag aagagtagag atagctggca tttcttggat
     1561 gcgtttttca aagcgagcaa tctcttcttt cttggctcct ggcaagactt gaactaggaa
     1621 accacctgca accttgacct tgtcttcctc gtccaaaagg acattgaggc cgaccgctga
     1681 aggcgtttgt tggctttcag taaggtaaaa ggcaaggtct tcaccgattt ctccagagat
     1741 gaggggagtt atagagttgt aaggatttcc agtaccgtag tctgtgataa cgaggaattg
     1801 accatttcca acaaaaggtc cgactaggac ttcaccagtc gcagtctttt tgatgtcaac
     1861 accaggattt tgaacatagc ctttgacgtt ccccttggta tcagcgacgg tgataatagc
     1921 acctagagag ctagatccca acaccttaac tgtaagtttg gtatttcctt tttcattggc
     1981 tgcgagaatc tggctagcga taagagttcg accaagcgct acagttgagc tagcttgggt
     2041 ttgatgtttt tcttgagcag tgcggacggt ttcagtgcta tcaaggacaa aagcacgaaa
     2101 ggctccgctt tctgatatag ttttaataat tttatccata gctactattt tagcataaaa
     2161 atgcccaaag ggggagccgt gtgtttactg attttcagga taatggacca ggaaatcagc
     2221 atgaaaataa aaagagaaac agattatttt agcatttgtc agatttatgc tatgcttaag
     2281 gtagaaaatg aaagggataa caaatgtatt taggagattt gatggagaaa gccgagtgtg
     2341 gtcaattttc aatactttcc tttctattac aagagtctca gacgaccgtc aaggctgtaa
     2401 tggaagaaac aggattttca aaagcaaccc taaccaaata tgtcaccctg ctcaatgaca
     2461 aggctttgga tagtggctta gagctggcta ttcactcaga agatgaaaat ctgcgtctgt
     2521 ctatcggtgc agctaccaag gggagagata ttcggagctt gtttttggag agtgctgtta
     2581 aataccagat tttggtttat cttctctacc accaacagtt tttagcccat cagctggctc
     2641 aagaattggt gattagcgag gctacgcttg gtcgtcactt ggctggttta aatcagattt
     2701 tgtcagaatt tgatttatcc atccaaaatg gccgttggcg aggtccagag catcagattc
     2761 actatttcta tttctgtctt ttccgaaagg tctggtcgag tcaggaatgg gaaggtcaca
     2821 tgcagaaacc agagagaaaa caggagattg ccaatttaga ggaaatctgc ggtgcaagtt
     2881 tgtctgcggg gcagaaattg gacttggttc tctgggctca catcagtcaa caacgtcttc
     2941 gggtcaatgc ttgtcagttt caagtcatag aagagaaaat gcgagggtat tttgacaata
     3001 tcttttatct tcgtttgctg agaaaggttc cgtccttttt tgctgggcaa catattccac
     3061 taggagttga ggatggtgag atgatgatat tcttctcttt tctcctatct catcgcattc
     3121 ttcctcttca tactatggag tatattcttg gttttggagg gcagttggca gatttactga
     3181 cgcaattgat tcaagaaatg aagaaggagg aactattggg ggattataca gaggaccatg
     3241 tcacctatga actcagtcag ctttgtgctc aagtctatct ctataagggc tatattttac
     3301 aggatcgcta caagtaccag ttagagaatc gtcatccata tttactgatg gaacatgatt
     3361 ttaaagagac agcagaggag atttttcatg ctctacctgc ttttcaacag gggacagatt
     3421 tagataagaa gattctctgg gaatggctcc agttaatcga atatatggct gaaaacggtg
     3481 gccagcatat gcggattggt ctggatttga catctggttt tcttgtcttt tcaaggatgg
     3541 cagccatttt gaaacggtat ttggaataca atcgttttat taccattgaa gcttatgacc
     3601 ctagtcggca ttatgatttg ctggttacca ataacccgat tcataagaag gaacagacac
     3661 cagtctatta tttaaaaaat gacttggata tggaggattt ggtagcgatt cgccagttat
     3721 tattcactta aaaggcttgg ttaatccagg tcttttttgt gaaattcaca caatctcctc
     3781 acattttttt aaaaattaaa aaaagttgat aaacaagaaa gcgctttatt ttgtatacta
     3841 gtaagtgtaa agaggaaaca cctcaagatc tttatcagga ggacagtaca tgtcacaaga
     3901 aaaatacatc atggccattg accagggaac tacaagttct cgtgccatca ttttcaacaa
     3961 aaaaggggaa aaggttagct cgagtcaaaa agagtttacc cagattttcc ctcaggcagg
     4021 ttgggttgag cacaatgcca atgaaatttg gaactctgtt cagtcagtta ttgcgggtgc
     4081 tttcatcgaa agtggtgtca agccaaatca aatcgaggca atcgggatta ccaaccaacg
     4141 tgaaacaacg gttgtctggg ataagaaaac aggacttcct atctacaatg ctatcgtttg
     4201 gcagtcacgc cagacagcac ctttggctga gcaactaaaa agccaaggtt atgtggaaaa
     4261 attccatgaa aagactggtt tgattattga tgcttacttc tctgctacca aggttcgttg
     4321 gattttggat catgtagaag gtgctcaaga gcgagcagaa aaaggggaat tgctctttgg
     4381 tactatcgat acttggttgg tttggaaatt gactgacggt gcggctcacg tgactgacta
     4441 ctcaaatgca gctcgtacca tgctttataa cattaaagaa ctcaaatggg atgatgagat
     4501 tttggaaatc cttaacattc cgaaggctat acttccagaa gttcgttcta actccgaaat
     4561 ctacggcaag acagctccat tccatttcta cggtggagag gtgccaatct caggtatggc
     4621 tggggaccaa caagcagccc tctttggaca gttggctttt gagccaggta tggttaagaa
     4681 tacttatgga acaggctctt tcatcatcat gaatactggg gaagagatgc agttgtctga
     4741 aaacaacctc ttgacaacca ttggttacgg aatcaacggt aaggtttatt atgccttgga
     4801 aggttctatc ttcatcgcag gaagtgctat tcagtggctt cgtgacggtc ttcgcatggt
     4861 tgaaaattca ccagaatctg aaaaatacgc tcgtgattct cacaacaacg atgaagttta
     4921 tgtcgttcca gcctttacag gtctaggcgc tccatactgg aaccaaaatg ctcgtggttc
     4981 cgtctttggt ttgactcgtg gaacaagcaa agaagacttt atcaaggcga ctttgcaatc
     5041 tattgcttat caagtgcgtg atatcatcga caccatgcaa gtggatactc agaccgccat
     5101 tcaagtactg aaggtggatg gtggtgcagc catgaacaac ttcctcatgc agttccaggc
     5161 ggatatttta ggcattgaca ttgcacgtgc taaaaacctg gaaacaacag ctctaggagc
     5221 ggccttccta gcaggtttgt cagtagggta ctggaaagac ttggacgagt tgaaactctt
     5281 gaacgagaca ggagaactct ttgagccatc tatgaacgaa tctcgcaagg aacaactcta
     5341 caagggctgg aagaaggctg tgaaagcaac tcaagtcttt gcggaagtag acgactaata
     5401 ctggcagaat aaagcgattt atttagaaag tgtgtaaata tggaattttc aaagaaaaca
     5461 cgtgaattgt caattaaaaa aatgcaggaa cgtaccctgg acctcttgat tatcggtgga
     5521 ggaatcacag gagctggtgt agccttgcag gcggcagcta gcggtcttga gactggtttg
     5581 attgaaatgc aagactttgc agaaggaaca tctagtcgtt caacaaaatt ggttcacgga
     5641 ggacttcgtt acctcaaaca atttgacgta gaagtggtct cagatacggt ttctgaacgt
     5701 gcagtggttc aacaaatcgc tccacacatt ccaaaatcag atccaatgct cttaccagtt
     5761 tacgatgaag atggagcaac ctttagcctc ttccgtctta aagtagccat ggacttgtac
     5821 gacctcttgg caggtgttag caacacacca gctgcgaaca aggttttgag caaggatcaa
     5881 gtcttggaac gccagccaaa cttgaagaag gaaggcttgg taggaggtgg agtgtatctt
     5941 gacttccgta acaacgatgc gcgtctcgtg attgaaaaca tcaaacgtgc caaccaagac
     6001 ggtgccctca ttgccaacca cgtgaaggca gaaggcttcc tctttgacga aagtggcaag
     6061 attacaggtg ttgtagctcg tgatctcttg acagaccaag tgtttgaaat caaggcccgt
     6121 ctggttatta atacaacagg tccttggagt gataaagtac gtaatttgtc taataaggga
     6181 acgcaattct cacaaatgcg cccaactaag ggagttcact tggtagtaga ttcaagcaaa
     6241 atcaaggttt cacagccagt ttacttcgac acaggtttgg gtgacggtcg tatggtcttt
     6301 gttctcccac gtgaaaacaa gacttacttt ggtacaactg atacagacta cacaggtgat
     6361 ttggagcatc caaaagtaac tcaagaagat gtagattatc tacttggcat tgtcaacaac
     6421 cgcttcccag aatccaacat caccattgat gatatcgaaa gcagctgggc aggtcttcgt
     6481 ccattgattg cagggaacag tgcctctgac tataatggtg gaaataacgg taccatcagt
     6541 gatgaaagct ttgacaactt gattgcgact gttgaatctt atctctccaa agaaaaaaca
     6601 cgtgaagatg ttgagtctgc tgtcagcaag cttgaaagta gcacatctga gaaacatttg
     6661 gatccatctg cagtttctcg tgggtctagc ttggaccgtg atgacaatgg tctcttgact
     6721 cttgctggtg gtaaaatcac agactaccgt aagatggctg aaggagctat ggagcgcgtg
     6781 gttgacatcc tcaaagcaga atttgaccgt agctttaaat tgatcaattc taaaacttac
     6841 cctgtttcag gtggagaatt gaacccagca aatgtggatt cagaaatcga agcctttgcg
     6901 caacttggag tatcacgtgg tttggatagc aaggaagctc actatctggc aaatctttac
     6961 ggttcaaatg caccgaaagt ctttgcactt gctcacagct tggaacaagc gccaggactc
     7021 agcttggcag atactttgtc ccttcactat gcaatgcgca atgagttgac tcttagccca
     7081 gttgacttcc ttcttcgtcg taccaatcac atgctcttta tgcgtgatag cttggatagt
     7141 atcgttgagc caattttgga tgaaatggga cgattctatg actggacaga agaagaaaaa
     7201 gcaacttacc gtgctgatgt cgaagcagct ctcgctaaca acgatttagc agaattaaaa
     7261 aattaagaaa aaataaaaga ggtggagggc agcattcctt gtcgcccgtc ccttcttttt
     7321 aatggagaca gaaagatgat gaatgaatta tttggagaat ttctagggac tttaatcctg
     7381 attcttctag gaaatggtgt tgttgcaggt gtggttcttc ctaaaaccaa gagcaatagc
     7441 tcaggttgga ttgtgattac tatgggttgg gggattgcag ttgcggttgc agtctttgta
     7501 tctggcaagc tcagtccagc ttatttaaac ccagctgtga ccatcggtgt ggccttaaaa
     7561 ggtggtttgc cttgggcttc cgttttgcct tatatcttag cccagttcgc aggggccatg
     7621 ctgggtcaga ttttggtttg gttgcaattc aaacctcact atgaggcaga agaaaatgca
     7681 ggcaatatcc tggcaacctt cagtactgga ccagccatca aggatactgt atcaaacttg
     7741 attagcgaaa tccttggaac ttttgttttg gtgttgacaa tctttgcttt gggtctttac
     7801 gactttcagg caggtatcgg aacctttgca gtgggaactt tgattgtcgg tatcggtcta
     7861 tcactaggtg ggacaacagg ttatgccttg aacccagctc gtgaccttgg acctcgtatc
     7921 atgcacagca tcttgccaat tccaaacaag ggagacggag actggtctta cgcttggatt
     7981 cctgttgtag gccctgttat cggagcagcc ttggcagtgc ttgtattctc acttttctag
     8041 tttatactct tcgaaaatca aattcaaacc acgtcagcgt cgccttaccg tactcaagta
     8101 cagcttgcgg ctagcttcct agtttgctct ttgattttca ttgagtatta gaaaacaatt
     8161 atgttgatag agcttgggca agagcccaat ttcagcaaaa aatgaagtaa atcttctcat
     8221 aataaaacgc atcatatcaa gcacgaaaat tccacgaggt caactacagt cagaaagctg
     8281 aacaacaagc caaaacgccc aaaaaaggcg gcaaaaagca agcacctgca agcaacgtgc
     8341 cgaaatggtc aaatcctgat tatgtcaacg aattagaccc aaaaatcgtt gatatgctag
     8401 tagaatttca caagtcacaa ggcactttgg aaactcccga ggcgcaagca gaaatcgccc
     8461 aaaaacgtga agaaatcgag caaaggagag ctgagcttga gggtaaaaaa caagagcttt
     8521 tgaaccgctt gaacaaatag agtttcgcaa gtattatgct tacaaattac ttgagcaatt
     8581 aactaaaata taaaccctgc ctttatatct aggcagggtt tatattttag aaattcacgt
     8641 aggttgttac ggtttttaca tacccagtat agtttgagtt tctatagtat tcagtgataa
     8701 acttccattt tctttgagca acatggatat aagtacttgt tatgtagtat ggatatgggc
     8761 tttgtgaatc caagtaagac tgataagctt gtataccaaa atatgctcca ccaattattg
     8821 caccccatgg accccccaat aaagcaccta tcctaccaat catataactg attccagcac
     8881 cagtcatgaa gttagcgaat gtgttagctt gtttattccc atgtattgtg ttgacgtaat
     8941 tccaaacatt aggatcgtat gatctaaaag atatatttag gtcgatttca ttcttttgat
     9001 aagccatata aaatgcccca ttgatataga cgccgtcagc acgtcgttca atagtgtcta
     9061 cacttccatc tggattgaca acctcaagaa cttcatcgct taaaatattt acttgcgtat
     9121 ctccgaaccg cactgatgag ccattctcaa actgagcctc accagataca actttagagt
     9181 ttgccgataa gctatcatca gcaaaaacaa acaagcgacg gggaaatgct agacatacag
     9241 aaaacagaca taactagcaa acacatgcat ttaaacatct tagacataac ggaaactcct
     9301 ttgtattttt gatttttttc aacttttatt atacaataaa accaaataaa aagaaagcgg
     9361 taacaatatg cttaatgcga aaatttttta tatattttta tgtttgatcg ttatcgaaac
     9421 tacaggcttg ttgttgttga aaagaggtct cgaaatgggt tatttagaca cagaagctat
     9481 tatcctcgca gttttttcat ttgcttttta caacctatgt tcattcgctt gggtctgctc
     9541 tacaataaaa aacaataaaa aataaataga cgtattttca aaaaaaaaaa aaatgcatat
     9601 ttatattagc aaaacgacga tttaaatcgt cgtttttttg t
//
LOCUS       DAVFER010000066         8593 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1105170250
            SAMEA2167659-rid19724873.denovo.066, whole genome shotgun sequence.
ACCESSION   DAVFER010000066 DAVFER010000000
VERSION     DAVFER010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2167659
            Sequence Read Archive: ERR388902
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8593)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8593)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928716.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928716.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 04:07:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,118
            CDSs (total)                      :: 2,073
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 120
            CDSs (without protein)            :: 120
            Pseudo Genes (ambiguous residues) :: 0 of 120
            Pseudo Genes (frameshifted)       :: 67 of 120
            Pseudo Genes (incomplete)         :: 47 of 120
            Pseudo Genes (internal stop)      :: 34 of 120
            Pseudo Genes (multiple problems)  :: 23 of 120
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8593
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2167659-rid19724873.denovo.066"
                     /strain="1105170250"
                     /db_xref="taxon:1313"
     gene            complement(164..796)
                     /locus_tag="VU534_001951"
     CDS             complement(164..796)
                     /locus_tag="VU534_001951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000200889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEU1514483.1"
                     /translation="MTSITAIFFDLDGTLVDSSIGIHNAFTYTFKELGVPSPDAKTIR
                     GFMGPPLESSFATCLSKDQISEAVQIYRSYYKAKGIYEAQLFPQIIDLLEELSSSYPL
                     YITTTKDTSTAQDMAKNLEIHHFFDGIYGSSPEAPHKADVIHQALQTHQLAPEQAIII
                     GDTKFDMLGARETGIQKLAITWGFGEQADLLNYQPDYIAHKPLEVLAYFQ"
     gene            complement(818..1690)
                     /gene="sdaAA"
                     /locus_tag="VU534_001952"
     CDS             complement(818..1690)
                     /gene="sdaAA"
                     /locus_tag="VU534_001952"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HEU1514484.1"
                     /translation="MFYSIKELVEQADLDFQGNVAELMITTEFELTGREREEVFLLME
                     RNLEVMKASVQLGLNENKSRSGLTGGDAAKLDHYIENGKTLSDYTILSAARNAIAVNE
                     HNAKMGLVCATPTAGSAGCLPSVLTAAIEKLDLSHEQQLDFLFAAGAFGLVIANNASI
                     SGAEGGCQAEVGSASAMSAAALTLAAGGTPYQASQAIAFVIKNMLGLICDPVAGLVEV
                     PCVKRNAMGASFAFIAADMALAGIESKIPVDEVIDAMYQVGASMPTAFRETAEGGLAT
                     TPTGRRLQKEIFGE"
     gene            complement(1699..2370)
                     /gene="sdaAB"
                     /locus_tag="VU534_001953"
     CDS             complement(1699..2370)
                     /gene="sdaAB"
                     /locus_tag="VU534_001953"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015606087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent
                     subunit beta"
                     /protein_id="HEU1514485.1"
                     /translation="MKSLRFQSVFDIIGPVMIGPSSSHTAGAVRIGKIVSSIFDDTPT
                     EVEFQLFNSFAKTYRGHGTDLALVAGILGMDTDDPEIPNSLEIAHKRGIKIVWTIQKD
                     SNAPHPNTTKITVKNAHKTISVTGISIGGGNIQVTELNGFAVSLNMNTPTIIIVHQDI
                     PGMIALVTEALSRYGINIAQMNVTREKAGEKAIMIIEVDSRNCDEAIEEIRKIPHLHN
                     VNFFK"
     gene            2612..3199
                     /locus_tag="VU534_001954"
     CDS             2612..3199
                     /locus_tag="VU534_001954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000843467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HEU1514486.1"
                     /translation="MKSITKKIKATLAGVAALFAVFAPSFVSAQESSTYTVKEGDTLS
                     EIAETHNTTVEKLAENNHIDNIHLIYVDQELVIDGPVAPVATPAPATYAAPAAQDETV
                     SAPVAETPVVSETVVSTVSGSEAEAKEWIAQKESGGSYTATNGRYIGRYQLTDSYLNG
                     DYSAENQERVADAYVAGRYGSWTAAKNFWLNNGWY"
     gene            complement(3251..3571)
                     /locus_tag="VU534_001955"
     CDS             complement(3251..3571)
                     /locus_tag="VU534_001955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEU1514487.1"
                     /translation="MQRLEVYKNYQRLYDLRIAILLNLSTLYLYNQDKNMCKQICYTL
                     LEDAKNKKSYDRLAICYVPIGICTDDSKLIQKGFSLLELTEETSMLSHLKKEVEIYYQ
                     AKER"
     gene            4002..4289
                     /locus_tag="VU534_001956"
     CDS             4002..4289
                     /locus_tag="VU534_001956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001230165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HEU1514488.1"
                     /translation="MRKLVKIGVASLMVCGILATTNALAVWVEGGQWNYGVGWTGTFG
                     YSDYLHSTRYHTATVRHGGRTSKDYAKPEAWARASLTKIPPTGMEYFYGFE"
     gene            4341..6449
                     /locus_tag="VU534_001957"
     CDS             4341..6449
                     /locus_tag="VU534_001957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000723955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HEU1514489.1"
                     /translation="MKKISNFCMLLLLLCTTFFVFNVNYTREVVRIQEMGKTVDSLDL
                     YLKDINEPAASVLRFFEDVSKEYKVSIIKTDSGDEVVKSGVFDKDTFPYQEFGISSLD
                     FTTDGEGVYSNKEISNKLGTIPTFLKAKPIQLMTFQTYIKDTSRSLNGRYTITSTQEM
                     DKDRIVQKWSDFFKIDQATLLEPTYKSAVEVINRDLLLSAIVFVLAILLLVLVTVYQP
                     MMEMKRVGVQKLLGFQDRAVLADVVKGNLYLLLGGALVINLGVFFLLDYKPKDLFPML
                     WLSHFLLLQLYLFISWLTYLLIQKMTISSLLKGFSSFKFGLIFNYVMKIGTTILLTAL
                     LIGVGRSLEQENKELAYQQQWVSQGNYLTLETFKLNDNLWQEELAGSGKSTDYFYRFY
                     QDLVEKTQAGYVQSSSLPVKNFVQSEQIQQYQLTDTVDVYYANRNFLKSKGFKLPNTG
                     IKKVILMPASTKGEEDKNQLLGKLIAFHSMKYEEQQKRTIEEMDVEIAYYEGDWSFFP
                     YSDKRKENLSNPIISLVNDSDMMWDEKASLSTTGLNNPIKIENTVQHQKEITELVEKL
                     SDGNYLKFSSIQAIQQEKVDSYRDAVRNFNLLFALFGLLSMMISYFLLVTTFLLKRRD
                     IITKKFMGWKLVDRYRPLLVLLLLGYSFPLLVLIFFAHAFLPLLLFAGFTCLDILFVL
                     GLASRMEKRSLVELLKGGIL"
     gene            6446..7087
                     /locus_tag="VU534_001958"
     CDS             6446..7087
                     /locus_tag="VU534_001958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU1514490.1"
                     /translation="MIELKNITKTIGGKVILDNLSLRIDQGDLVAIVGKSGSGKSTLL
                     NLLGLIDGDYSGRYEIFGQTNLAVNSAKSQTIIREHISYLFQNFALIDDETVEYNLML
                     ALKYVKLPKKDKLKKVEEILERVGLSATLHQRVSELSGGEQQRIAVARAILKPSQLIL
                     ADEPTGSLDPENRDLVLKFLLEMNREGKTVIIVTHDAYVAQQCHRIIELGEGK"
     gene            7294..8100
                     /locus_tag="VU534_001959"
     CDS             7294..8100
                     /locus_tag="VU534_001959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001038484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEU1514491.1"
                     /translation="MNKMKKVLMTMFGLVMLPLLFACSNNQSAGIEAIKSKGKLVVAL
                     NPDFAPFEYQKVVDGKNQIVGSDIELAKAIATKLGVELELSPMSFDNVLASVQSGKAD
                     LAISGVSKTDERSKVFDFSIPYYTAKNKLIVKKSDLTTYQSVNDLAQKKVGAQKGSIQ
                     ETMAKDLLQNSSLVSLPKNGNLITDLKSGQVDAVIFEEPVSKGFVENNPDLAIADLNF
                     EKEQDDSYAVAMKKDSKKLKEAVDKTIQKLKESGELDKLIEDAFKASIEK"
     gene            8066..8536
                     /locus_tag="VU534_001960"
     CDS             8066..8536
                     /locus_tag="VU534_001960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012386596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate synthase"
                     /protein_id="HEU1514492.1"
                     /translation="MRMPLKHPLKNRKKEKNMSKEKVILAYSGGLDTSVAITWLKKDY
                     DVVSVCMDVGEGKDLDFIHDKALKVWAVESYVIDVKDEFATDYVLVAHQSHAYYEQKY
                     LLVSALSRPLISKKLVEIAHQIGATTIAHGCTGKGNDQVEYQIAVAKKANEAKK"
BASE COUNT         2598 a         1529 c         1878 g         2588 t
ORIGIN      
        1 atccacaacc ttaaaacagt gttttgagct gacttcgtca gttccatcta caaccttaaa
       61 acagtgtttt gagctgcccg cagctagttt cctagtttgc tctttgattt tcattgagta
      121 ttacttcatt ttcttctgaa atggaattgt tacccagtct atgctattga aaatacgcca
      181 aaacttctaa gggtttgtga gcgatataat caggttgata gtttagtaga tctgcttgct
      241 ctccaaatcc ccaagtgatg gccaatttct gaatacctgt ttctcgagct cccagcatat
      301 caaacttggt atctccgatg atgatggctt gttctggtgc tagttgatgt gtctgcaagg
      361 cttggtgaat gacatctgcc ttatggggtg cttcagggct agaaccataa atgccatcaa
      421 agaaatgatg gatttccaag ttttttgcca tgtcttgagc agtagatgta tcctttgtcg
      481 tggtgatgta gagtggataa ctgctcgata actcctcaag caagtctata atctgaggaa
      541 agagttgagc ttcatagatg ccttttgcct tatagtaaga acgatatatc tgcacggctt
      601 cagaaatttg gtctttggac aggcaggtcg caaaactact ttcgagaggt ggtcccataa
      661 aaccacgaat agttttggca tcagggctag gcacccccag ctctttaaag gtataggtaa
      721 aggcattgtg aatcccgata gaactatcaa cgagggttcc atccaaatcg aaaaaaatcg
      781 ctgtgataga ggtcatggtt tctcctattt gataagctta ttctccgaaa atttcttttt
      841 ggaggcgacg accagtaggg gtggtagcga gtccaccttc agctgtttca cgaaaggcag
      901 ttggcatgct tgctcctact tggtacatgg catcgatcac ttcatccaca gggattttag
      961 attcgatacc tgccaaggcc atgtctgctg cgatgaaagc aaagctagct cccatggcat
     1021 tacgtttgac acagggaact tcgaccaaac ctgcaacagg gtcacagatg aggcctagca
     1081 tatttttaat gacaaaggca atagcttgac tggcctgata aggtgttcca cctgcagcca
     1141 gagtcaaggc ggcagcactc atagcagagg ctgaaccaac ttcagcttga cacccaccct
     1201 cagcacctga gatggaggca ttgtttgcga tgactagtcc aaaggcacca gcagcaaaga
     1261 ggaaatccaa ttgttgctcg tggctgaggt ctaatttttc aatagcagca gtgagaacgg
     1321 atggcagaca gccagcactt ccagcggttg gagtggcaca gaccaagccc attttggcat
     1381 tgtgttcatt gactgcgatg gcatttcggg cagccgagag aatcgtataa tctgacagag
     1441 tttttccgtt ttcgatgtag tgatccaatt tggcagcatc tccacctgtc aggccactac
     1501 gagatttatt ttcattgagg ccaagttgga cagaggcttt cataacttcc agattgcgtt
     1561 ccatgagaag gaagacttct tcacgttcgc gaccggtcaa ttcaaactct gttgtaatca
     1621 tgagttctgc gacatttcct tgaaagtcca gatctgcttg ctcgaccaat tctttgatag
     1681 aataaaacat gcttcctcct atttaaagaa attgacattg tggagatgag ggatttttcg
     1741 aatttcttcg atagcctcat cacagttgcg actgtcaact tcgataatca taatggcttt
     1801 ttcaccagct ttttcacgag tgacattcat ctgggcgata ttgataccat agcgggaaag
     1861 cgcctctgta acaagggcaa tcatacctgg aatatcttga tgaacgatga tgatagtcgg
     1921 tgtattcata ttgagagaga cggcaaaacc attgagttcg gttacctgaa tatttcctcc
     1981 accgatagaa ataccagtca cgctgatggt cttgtgggca tttttaacag taattttagt
     2041 ggtgttaggg tgaggggcat tgctgtcttt ctgaatggtc cagacaatct tgataccacg
     2101 cttgtgggca atttccagac tatttggaat ttcaggatca tctgtatcca ttcctaaaat
     2161 acctgcaaca agggctaggt ctgttccgtg accacgatag gtcttggcaa atgagttaaa
     2221 aagttggaat tcaacttctg tcggagtatc atcaaaaatg gaagagacaa tcttcccaat
     2281 acgaacagca ccagcggtat ggctactaga tgggccaatc ataactggtc cgatgatatc
     2341 aaagacagat tgaaaacgaa gtgatttcat cagtttcccc ttataaaaat tcttatctct
     2401 attatatcaa agaatgaggg gcttggcttt aattgtggat gaaaaccttt ctaatacctc
     2461 aaatagcata aaaatagtat cttttatgac aaaaaacacc ttatttaggg aaataaaaaa
     2521 taattttgta atatttctac ataaaagtgt caagaaacgg taatatttaa agggtatgat
     2581 agaactatag aaagaaggag aattttcgaa tatgaaatca ataactaaaa agattaaagc
     2641 aactcttgca ggagtagctg ccttgtttgc agtatttgct ccatcatttg tatctgctca
     2701 agaatcatca acttacactg ttaaagaagg tgatacactt tcagaaatcg ctgaaactca
     2761 caacacaaca gttgaaaaat tggcagaaaa caaccacatt gataacattc atttgattta
     2821 tgttgatcaa gagttggtta tcgatggccc tgtagcgcct gttgcaacac cagcgccagc
     2881 tacttatgcg gcaccagccg ctcaagatga aactgtttca gctccagtag cagaaactcc
     2941 agtagtaagt gaaacagttg tttcaactgt aagcggatct gaagcagaag ccaaagaatg
     3001 gatcgctcaa aaagaatcag gtggtagcta tacagctaca aatggacgtt atatcggacg
     3061 ttaccaatta acagattcat acctgaacgg tgactactca gctgaaaacc aagaacgtgt
     3121 agcagatgcc tacgttgcag gacgttacgg ttcatggact gctgctaaaa acttctggct
     3181 taacaatggc tggtattaag aactaacgaa caaataatat gtaaagagtc gaggaaatcc
     3241 ctcggctttt ttatctttcc ttcgcttggt aatagatctc tacttctttt ttgagatgag
     3301 acagcataga agtttcctcg gttagctcca gaagggagaa ccctttttgg ataagtttag
     3361 aatcgtctgt acaaatccca atagggacat agcagatagc cagcctatcg taacttttct
     3421 tattcttggc gtcctccagt aaagtatagc agatttgctt acacatgttt ttatcttgat
     3481 tgtatagata gagtgtggaa aggttgagca ggattgctat tcgcaagtca tataaacgtt
     3541 gatagttttt atagacttct aagcgttgca agattttctc ggattattga caaataaacg
     3601 gacattctga tagacgattg ccctagcggc ttagtgtaaa ctttacaaat ttggcttgta
     3661 atttttttat aaaattcact tcagatactt gacagttatt atattttcgc ttatgcttat
     3721 tatatagata aaaggacggg ataggagttt aaaaatttga aagcgctatc catattgttt
     3781 attggactga ttcttgagta atagttagag tttgcttaat actactctgg ttgttcaagg
     3841 acctgataca gaagcgcacc attctcccgg ttaagagtaa gttcgttgtt aaaaaatgaa
     3901 atgagataga aggaaggtga gtccaatgga ctacgatact tgttgataaa ttactatagc
     3961 tgtttttacg gaacagctct cgataatagg agaaataaat catgagaaaa ttagttaaaa
     4021 ttggtgttgc atctttaatg gtatgtggta tacttgctac tacaaatgct ttagcagtat
     4081 gggttgaggg tggtcaatgg aactatggag taggttggac aggaactttt ggatattctg
     4141 attacttaca ttctactcga tatcatacag caactgttag acatgggggt agaacctcta
     4201 aggattatgc aaaacctgag gcatgggcta gagcttccct caccaagatt ccgccaacag
     4261 gaatggaata tttctatgga tttgagtaaa attcttccct ctcctatttg gagagggaaa
     4321 actgtagtgg aggcactttt atgaaaaaaa tcagtaattt ctgtatgtta ctcctgcttc
     4381 tgtgtaccac tttttttgtt tttaatgtaa actatacacg agaagtggtt cggattcaag
     4441 aaatgggaaa gactgtagat tctttggatt tgtatttgaa agatattaac gaacctgcag
     4501 cgtctgttct tcgatttttt gaggatgtat caaaggagta taaagtctcc atcatcaaaa
     4561 cagacagtgg tgatgaggtg gtcaagtctg gtgtttttga taaagatacc ttcccctacc
     4621 aagagtttgg gatttcttct cttgatttta ccacagatgg tgaaggagtc tatagtaata
     4681 aagaaatttc caataaactt ggtacgattc cgacctttct aaaagccaaa cctattcagc
     4741 ttatgacttt tcaaacctat atcaaggata catctcgtag tttaaatggt cgctatacga
     4801 taacttctac acaagagatg gacaaggata ggattgtaca gaaatggagc gattttttca
     4861 agatagacca ggctaccttg ctagagccga cctacaaaag tgcagtggaa gtcataaatc
     4921 gagatttgct tttatctgcc attgtttttg tcttggctat tttgcttctt gtgttagtga
     4981 cagtgtatca accgatgatg gagatgaaaa gagttggggt acaaaaatta cttggttttc
     5041 aagatagggc tgttttagct gatgttgtaa aaggcaacct ttacctcctc ctaggtgggg
     5101 ctcttgtgat caatctaggc gtgtttttct tgcttgatta taagccaaaa gatttgtttc
     5161 ctatgctgtg gttgtctcat tttttgctgt tgcagcttta tctctttatc agttggttga
     5221 cttacctctt aatccaaaaa atgacaatca gctctctgct gaaaggtttt tcatctttca
     5281 aatttggtct tatcttcaat tatgtgatga aaatagggac aactatttta ctgacggcct
     5341 tactgattgg ggtgggcaga agtttagaac aagaaaacaa agaacttgct tatcagcaac
     5401 agtgggtaag tcaaggtaat tacctgacct tagaaacctt caaactcaat gataatctgt
     5461 ggcaagaaga gctagcaggg tcagggaaat ctacagatta tttctatcga ttttatcagg
     5521 atttggtaga aaaaacgcag gcgggctatg tgcagagtag cagtcttcct gtaaaaaatt
     5581 ttgtccaatc agaacagatt cagcaatatc agttaacaga tacggtggat gtttactatg
     5641 ccaatcgcaa ttttctaaag agcaagggat tcaagctacc aaataccggt attaaaaaag
     5701 ttattttgat gccagcaagt acgaaaggtg aagaagataa aaatcagctc ttggggaagt
     5761 taattgcctt tcattcgatg aagtatgaag agcagcaaaa acgaacgata gaggagatgg
     5821 atgtcgagat tgcctattat gaaggagatt ggtcattttt cccatatagt gataagcgaa
     5881 aggaaaatct ctccaatcca attattagct tggtcaatga ttctgatatg atgtgggatg
     5941 agaaagcctc cctgtcaaca actggcttaa ataatccgat taaaattgaa aatacggttc
     6001 aacatcaaaa agagattaca gagttagttg agaaattgtc agatggaaat tatttaaaat
     6061 tttcatctat tcaagccatt caacaagaga aagtggattc ttatcgagat gctgttcgga
     6121 attttaacct actctttgct ttgtttggtc tccttagcat gatgatttcc tacttcttac
     6181 tagtaacaac tttcttattg aagcgcaggg atatcattac caagaagttt atggggtgga
     6241 aactggtcga tcgctaccgt cctctcctcg ttctgctctt gctgggctat agtttccctc
     6301 ttctagtctt gattttcttt gcccatgcgt tcttaccact tctactgttt gcaggtttta
     6361 catgtctgga tatactattt gtgctaggct tagcttctag gatggagaaa agaagtctag
     6421 tagagttatt gaaagggggc atcttatgat tgagttgaaa aatattacca aaaccattgg
     6481 gggaaaagtg attttggata acttatctct caggattgat cagggggatt tggtagctat
     6541 tgttggtaag agtggtagtg ggaagtcgac cttgttaaat ttattgggtt tgatagatgg
     6601 tgattatagc ggacggtatg agatttttgg tcagacaaat ctagcggtta attctgctaa
     6661 gtcgcaaaca ataatccgtg aacatatctc ttatctgttt caaaattttg ccctgattga
     6721 tgatgaaacg gtcgagtaca atctcatgct ggcgctgaaa tatgtgaaat tgcctaagaa
     6781 agacaagctc aaaaaggtgg aagagatttt agagagagta ggtttatcag ctactttgca
     6841 tcaaagggtc tccgagttgt ctgggggcga acaacaacga attgcagttg ctagagccat
     6901 cttaaaaccc agccagctga ttttagccga tgaaccgaca ggttctctgg atcctgaaaa
     6961 tagagatttg gtcttgaagt ttctcttaga gatgaatcga gaggggaaaa cagtcattat
     7021 cgtgacccac gatgcttatg tagcccaaca atgtcatcga atcattgaat taggcgaggg
     7081 aaaatgagtt cgttcagctt catttgaccg actgaatact catatttttc agagagaaat
     7141 agcataaata ggcctaggaa tgatattttt atgtcatttt cctgggtttt tctgttttaa
     7201 attgaaaaaa attacaattt aggcttgaca aaggatgcat atagatgtat tgtttataca
     7261 aataaaagga ataaacataa agtaggcttt attatgaata agatgaagaa ggtgttgatg
     7321 acgatgtttg gtttagtgat gctcccccta ctatttgctt gtagcaacaa tcaatcggct
     7381 ggaattgaag ccatcaagtc caaaggaaaa ttggttgtag ccctcaatcc ggattttgct
     7441 ccatttgaat accaaaaagt ggttgatggg aaaaatcaga ttgtgggttc agatatcgaa
     7501 ttagccaagg ctatcgcaac aaaactaggt gtcgaattgg aactatctcc catgagtttt
     7561 gataatgtac tggctagtgt tcaatcagga aaagccgacc ttgccatatc aggtgtttct
     7621 aagacagatg aacggagcaa ggtgtttgac ttttccattc cctactatac tgcaaaaaat
     7681 aaactcattg tcaaaaaatc tgacttgact acttatcagt ctgtaaacga cttggcgcag
     7741 aaaaaggttg gagcgcagaa aggttcgatt caagagacga tggcgaaaga tttgctacaa
     7801 aattcttccc tcgtatctct gcctaaaaat gggaatttaa tcacagattt aaaatcagga
     7861 caagtggatg ccgttatctt tgaagaacct gtttccaagg gatttgtgga aaataatcct
     7921 gatttagcaa tcgcagacct caattttgaa aaagagcaag atgattccta cgcggtagcc
     7981 atgaaaaaag atagcaagaa attgaaagag gcagtcgata aaaccattca aaagttgaag
     8041 gagtctgggg aattagacaa actcattgag gatgccttta aagcatccat tgaaaaatag
     8101 aaagaaggaa aagaacatga gtaaagaaaa agtaattttg gcctattctg gcggtttgga
     8161 cacatcagtt gctattacct ggttaaagaa agactatgat gttgtttcag tttgtatgga
     8221 tgtgggtgaa gggaaagact tagatttcat ccatgataag gctcttaagg tttgggcagt
     8281 agaatcttat gtcattgatg ttaaggacga atttgctaca gattatgtgc tagtggctca
     8341 tcagtcacat gcctattatg aacaaaagta tctcttggta tctgccttga gccgccctct
     8401 gatttctaaa aaattggttg aaatagcgca tcagatagga gcgactacaa ttgctcatgg
     8461 ttgtaccggt aaggggaatg accaagtcga ataccagatt gcagtcgcta agaaagcgaa
     8521 tgaagctaaa aagtgatgga gtgatgggtt cagaataaga ggttggtaga ttatcagcct
     8581 ctttcttgtc gtt
//
LOCUS       DAVFER010000067         8174 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1105170250
            SAMEA2167659-rid19724873.denovo.067, whole genome shotgun sequence.
ACCESSION   DAVFER010000067 DAVFER010000000
VERSION     DAVFER010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2167659
            Sequence Read Archive: ERR388902
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8174)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8174)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928716.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928716.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 04:07:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,118
            CDSs (total)                      :: 2,073
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 120
            CDSs (without protein)            :: 120
            Pseudo Genes (ambiguous residues) :: 0 of 120
            Pseudo Genes (frameshifted)       :: 67 of 120
            Pseudo Genes (incomplete)         :: 47 of 120
            Pseudo Genes (internal stop)      :: 34 of 120
            Pseudo Genes (multiple problems)  :: 23 of 120
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8174
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2167659-rid19724873.denovo.067"
                     /strain="1105170250"
                     /db_xref="taxon:1313"
     gene            complement(119..394)
                     /locus_tag="VU534_001961"
     CDS             complement(119..394)
                     /locus_tag="VU534_001961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002950996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HEU1514493.1"
                     /translation="MANKQDLIAKVAEATELTKKDSAAAVEAVFAAVADYLAAGEKVQ
                     LIGFGNFEVRERAERKGRNPQTGKEMTIAASKVPAFKAGKALKDAVK"
     gene            complement(500..1339)
                     /locus_tag="VU534_001962"
     CDS             complement(500..1339)
                     /locus_tag="VU534_001962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000161411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEU1514494.1"
                     /translation="MTKIKIVTDSSVTIEPELVKQLDITIVPLSVMIDNVVYSDADLK
                     EEGKFLQLMQESKNLPKTSQPPVGVFAEIFEDLCKDGGQILAIHMSHALSGTVEAARQ
                     GASLSTADVTVVDSSFTDQALKFQVVEAAKLAQEGKDMEAILSHVEEVKNHTELYIGV
                     STLENLVKGGRISRVTGLLSSLLNIRAVMQMKDHELQPMVKGRGTKTFKKWLDELITS
                     LSERAVAEIGISYSGSDDWAKEMKESLQAYVEKPISVLETGSIIQTHTGENAWAILIR
                     YHS"
     gene            1481..2329
                     /locus_tag="VU534_001963"
     CDS             1481..2329
                     /locus_tag="VU534_001963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000592058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEU1514495.1"
                     /translation="MIKKIYPIFTILLGAAIYAFGLTYFVVPHHLFEGGATGITLITF
                     YLFKIPVSLMNLLINIPLFILAWKIFGAKSLYSSLLGTLALSGWLAFFEHIPLHIDLQ
                     GDLLITALIAGILLGIGLGIIFNAGGTTGGTDILARILNKYTHISIGKLLFILDFCIL
                     MLILLIFKDLRLVSYTLLFDFIVSRVIDLIGEGGYAGKGFMIITKRPDQLAKAINDDL
                     GRGVTFISGQGYYSKENLKIIYCIVGRNEIVKTKEMIHRIDPQAFITITEAHEILGEG
                     FTFEKE"
     gene            complement(2422..3339)
                     /locus_tag="VU534_001964"
     CDS             complement(2422..3339)
                     /locus_tag="VU534_001964"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional riboflavin kinase/FAD synthetase"
                     /protein_id="HEU1514496.1"
                     /translation="MIITIPIKNQKDIGTPSDSVVVLGYFDGIHKGHQELFRVANKAA
                     RKDLLPIVVMTFNESPKIALEPYHPDLFLHILNPAERERKLKREGVEELYLLDFSSQF
                     ASLTAQEFFATYIKAMNAKIIVAGFDYTFGSDKKTAEDLKNYFDGEVIIVPPVEDEKG
                     KISSTRIRQAILDGNVKEAGKLLGAPLPSRGMVVHGNARGRTIGYPTANLVLLDRTYM
                     PADGVYVVDVEIQRQKYRAMASVGKNVTFDGEEARFEVNIFDFNQDIYGETVMVYWLD
                     RIRDMTKFDSVDQLVDQLKADEEVTRNWS"
     gene            3777..3982
                     /locus_tag="VU534_001965"
                     /pseudo
     CDS             3777..3982
                     /locus_tag="VU534_001965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844775.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
     gene            complement(4293..4586)
                     /gene="rpmA"
                     /locus_tag="VU534_001966"
     CDS             complement(4293..4586)
                     /gene="rpmA"
                     /locus_tag="VU534_001966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HEU1514497.1"
                     /translation="MLKMTLNNLQLFAHKKGGGSTSNGRDSQAKRLGAKAADGQTVTG
                     GSILYRQRGTHIYPGVNVGRGGDDTLFAKVEGVVRFERKGRDKKQVSVYPIAK"
     gene            complement(4603..4947)
                     /locus_tag="VU534_001967"
     CDS             complement(4603..4947)
                     /locus_tag="VU534_001967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HEU1514498.1"
                     /translation="MIQAVFERAEDGELRSAEITGHAESGEYGLDVVCASVSTLAINF
                     INSIEKFAGYEPILELNEDEGGYLMVEIPKDLPSHQREMTQLFFESFFLGMANLSENY
                     SEFVQTRVITEN"
     gene            complement(4963..5277)
                     /gene="rplU"
                     /locus_tag="VU534_001968"
     CDS             complement(4963..5277)
                     /gene="rplU"
                     /locus_tag="VU534_001968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HEU1514499.1"
                     /translation="MSTYAIIKTGGKQVKVEVGQAVYVEKLNVEAGQEVTFNEVVLVG
                     GENTVVGTPLVAGATVVGTVEKQGKQKKVVTYKYKPKKGSHRKQGHRQPYTKVVINAI
                     NA"
     misc_feature    complement(5313..5400)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00559"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L21 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00559"
     gene            complement(5459..6163)
                     /locus_tag="VU534_001969"
     CDS             complement(5459..6163)
                     /locus_tag="VU534_001969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004241810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1275 domain-containing protein"
                     /protein_id="HEU1514500.1"
                     /translation="MGGKMRLLPIRKISRQSKRLALFLTFCAGYVDAYTFIVRGNTLV
                     AGQTGNVVFLSVELIKNNVSDVRDKVLTLLAFMMGVFLLTIYKEKLRIVKKPILSLIP
                     LAILSIIIAFVPQTVDNIYLVPPLAFCMGLVTTAFGEVSGIAYNNAFMTGNIKRTMLA
                     FGDYFRTKHTPFLREGFIFVSLLSSFVLGVVFSAYLTIFYHEKTILGVPIMMSVFYLS
                     MLFASWQKKVKEKASF"
     gene            6565..6864
                     /locus_tag="VU534_001970"
     CDS             6565..6864
                     /locus_tag="VU534_001970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HEU1514501.1"
                     /translation="MMNMQNMMRQAQKLQKQMEQSQAELAAMQFVGKSAQDLVQATLT
                     GDKKVVSIDFNPAVVDPEDLETLSDMTVQAINSALEQIDETTKKKLGAFAGKLPF"
     gene            7045..8174
                     /locus_tag="VU534_001971"
                     /pseudo
     CDS             7045..8174
                     /locus_tag="VU534_001971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         2583 a         1665 c         1361 g         2565 t
ORIGIN      
        1 tatatacaat attttcggaa cattcaactt tttaactcta tttattacta gatttcataa
       61 ttaaaaaacc tactgaccaa gctagaaagc ttgatacaat aggcttttta aagactgatt
      121 atttaacagc gtctttaaga gctttaccag ctttgaatgc tggtacttta gaagctgcaa
      181 ttgtcatttc tttaccagtt tgtgggttgc gacctttacg ttctgcgcgc tcacgaactt
      241 caaagttacc aaaaccgatc aattgaactt tttcaccagc tgcaagatag tcagctactg
      301 ctgcaaatac agcttcaact gctgctgctg agtctttctt agtcaattct gtagcttctg
      361 ctactttagc gatcaaatct tgtttgtttg ccatgttaat gattcctcca aataatttct
      421 aattaacaaa tataatcata tcctaaaatc ccttttaggt caagttaaaa acgctatttc
      481 ttcccatttt atttattttt taggagtggt aacgtatcaa aatagcccaa gcgttctcac
      541 ccgtgtgagt ttgaataatg gaacccgttt ccaaaacaga aattggcttt tcaacataag
      601 cttgtaagct ttctttcatc tcttttgccc aatcatcact accagaatat gaaattccaa
      661 tctctgctac agcacgttca gaaagcgatg ttatcaactc atctaaccat tttttaaatg
      721 ttttagttcc acgaccttta accattggct gcaattcatg gtctttcatt tgcatgacag
      781 cacggatatt gagaagagag ctcaacaagc cagttacacg gctaattcgt ccacctttga
      841 caagattttc caaagttgaa acaccaatat aaagctctgt atggttttta acctcttcta
      901 catgagataa aattgcctcc atatctttac cttcttgagc taacttcgca gcctcaacaa
      961 cttggaattt cagggcttgg tcagtgaagg aactatcaac aacagtcaca tctgcagtag
     1021 ataggctagc accttggcgt gctgcttcta ccgtacccga aagagcatgg gacatatgaa
     1081 tagcaagaat ctggccacca tctttgcata ggtcttcaaa aatctcagca aagacaccta
     1141 caggtggctg acttgttttc ggaagattct tactttcttg catcaactga agaaatttac
     1201 cttcttcttt caaatccgca tcagaataaa caacattatc aatcattaca gataatggaa
     1261 caattgtaat atctaattgc tttactagtt caggttcaat agtaacagat gaatcggtta
     1321 caatcttaat ttttgtcata gtatcaatct ttctatttta ggattcagat tggtttcctt
     1381 acttctaatt atatcaaaaa aaagattaaa aatcctaatg gagtcaatca aattttccgt
     1441 aaaatttgat ataatcaact tataagaaaa gaggtgtcct atgattaaaa aaatttaccc
     1501 catttttacc attttactag gtgctgctat ttatgctttt ggactgactt attttgtagt
     1561 tccccatcat ctctttgaag gaggggcgac aggcattacc ctcatcacct tttatctttt
     1621 taaaatccct gtttccctca tgaacctgct gattaatatt ccccttttca tcctagcttg
     1681 gaagattttt ggagccaaat ccctctattc tagtttacta ggaaccttag ctttgtccgg
     1741 ctggttagct ttttttgagc atattcccct tcatattgat cttcaaggtg atttactaat
     1801 cacagccctt atagcgggaa tcctattggg aattggcctt ggaattattt ttaatgctgg
     1861 aggtacaact ggcggaactg atattctagc tcgtattctc aacaaataca ctcatatatc
     1921 cataggaaaa ctgctcttta tcttagattt ttgtattctc atgttgattc tcctaatctt
     1981 caaggatttg agattggttt cctacacgct tttgtttgat tttattgttt ctcgtgttat
     2041 tgatttgatt ggtgaaggag gatatgccgg caaaggcttt atgattatca caaaacgtcc
     2101 tgaccaactt gctaaggcga ttaatgatga cctcggaaga ggtgttactt ttatttctgg
     2161 tcaaggctac tatagtaaag aaaatttgaa aatcatctac tgtattgtcg gaagaaatga
     2221 aattgtgaaa acgaaggaaa tgattcatcg aatcgatcct caagccttta taactattac
     2281 agaagcccat gaaatcctag gagaaggctt cacctttgaa aaagaataaa aagaggtaat
     2341 gtcgtgacct caaaagttag actaaatcat ctatcttttg ggttacagac aacctctttt
     2401 ttattttatt tactcaagct cttaagacca attccgagtt acttcttcat cagcctttaa
     2461 ctgatccact aattggtcaa ctgagtcaaa tttggtcata tctcgaatgc gatcaagcca
     2521 ataaaccatg acggtttccc cataaatatc ttgattaaaa tcaaaaatat tgacttcaaa
     2581 acgtgcttct tctccatcaa aggtcacatt tttcccgaca ctagccatag cacgatactt
     2641 ctgtctttga atctcaacat caacaacata aacgccatct gctggcatat aagtacggtc
     2701 taaaagcact aaattcgctg tcggataacc aattgtacga ccacgagcat taccatgaac
     2761 caccatacct cttgatggaa gcggtgcccc caaaagtttt cctgcttctt tcacatttcc
     2821 atctaaaata gcttgacgga tacgagttga actaatcttt cctttctcat cttctacagg
     2881 tggaacaatg ataacttctc catcaaagta attctttaaa tcttctgctg tttttttgtc
     2941 agaaccaaat gtataatcaa aacctgcaac aataattttg gcattcatag ccttgatata
     3001 agttgcaaag aattcttgtg cagtgagact agcgaattga ctactaaaat caaggagata
     3061 taattcttct acaccttcgc gctttaattt tctttcacgt tcagcagggt tcaaaatatg
     3121 caaaaacaaa tctggatgat aaggctctaa agcgatcttt ggagattcat taaaggtcat
     3181 aacgacgata ggcaacaaat cctttctcgc agccttgttg gcaacacgaa ataattcttg
     3241 atgcccctta tgtatgccat caaaatagcc gagaacaacg actgaatcag atggtgtgcc
     3301 aatatctttt tggtttttta taggaatagt aataatcata aaataattat atcatagcga
     3361 tagctatttc tggaacagaa aatctgaaat gttgtttttt tcacatgaag tgtacctgtt
     3421 ttcaaaaagc actttattct atcgttgctt aactatgaac tttgcaatat tcttctcaaa
     3481 aacttgtagg acatcttcaa aattttgcaa ggagtgatta gacttgttcg gtaaccataa
     3541 agtgtcatac tatgcttatg tatgaaaaag caatgcaact aactcctgag aactttaaat
     3601 tactaattgg tgccgaaaag gtagaattta gaatcgaggt acacctatgg ctgtaaaatt
     3661 tacaaaatga gacaacttgg gcaagatgtt tgaagaattt cctaaactcc ctgatttgaa
     3721 gcaagtcact ttccctaatg acaaagaaaa aagccaaaac agcaaagaaa aactagatga
     3781 ctgctttcca acaactccca tctagtgtgc ttcagactgg gctatttttc tctccatctg
     3841 ttagcttgga ttctcagacc gtttcagcta aagaatatct tttcccttat cagaaggaac
     3901 ggctcaagcc attcagacaa gtgaagggac gacaagccaa tatttgaaac cagatagcag
     3961 ttcttatagt caattgaaat aaaatctgaa gaaatcgagt aggaaactca tatcaatgtt
     4021 taacagtgtt ctattccaga ttcatactca atgaaaatta aagtgcaaac taggaagtta
     4081 gccgcaggct gtacttgagt acggcaaggt gaaattgaca tggtttgaat ttgattttcg
     4141 aagagtatca atccactata catattaaaa agtatgggta ccaaaacaaa aaaacaggct
     4201 ctccgaaaac tcggaaagcc ttattttaag ctgtttctag cttcctcacc tttacatttc
     4261 aaggttcggg ataaaaggtt caatggacct ttttatttag cgattgggta aacagaaact
     4321 tgttttttat cgcgtccttt acgttcaaag cgtactacgc cttcaacttt agcgaacaaa
     4381 gtatcatctc caccacgacc aacgtttaca cctggataga tgtgtgtacc acgttgacgg
     4441 taaaggattg atccacctgt tacagtttgt ccgtcagctg ctttagctcc aagacgtttt
     4501 gcttgtgaat cacgtccgtt tgatgtagaa cctccacctt ttttgtgggc gaaaagttgc
     4561 aagttgttaa gagtcatttt taacataatg ttttcctccg tgttagtttt ctgtgataac
     4621 tctggtttgg acgaactcag aatagttctc cgataagttt gccataccta agaaaaatga
     4681 ttcaaagaat aactgggtca tttctctctg gtgtgaagga agatcttttg gtatttcaac
     4741 catcagatag ccaccttcat cttcgtttaa ttctaggatt ggttcatagc ctgcaaattt
     4801 ctcaatagaa ttgataaagt taatggcaag cgtagaaacc gatgcacaca cgacatctaa
     4861 gccgtattcg ccactctcgg cgtgtccagt aatttccgca ctcctcagct cgccatcttc
     4921 ggctctctca aagactgcct gtatcatgtg ttctccttaa aattaagcgt tgattgcgtt
     4981 gatgacaact tttgtatatg gttgacggtg accttgttta cggtggctac cttttttagg
     5041 tttgtacttg taagtaacca ctttcttttg ttttccttgt ttttcaacag ttccaactac
     5101 agtagctcca gcaacaagtg gagttccgac aacagtgttt tcaccaccaa caagaacaac
     5161 ttcgttaaaa gtaacttctt gaccagcttc aacgttcaat ttttcaacgt aaactgcttg
     5221 accaacttca actttaactt gttttccgcc agttttgata attgcgtatg tgctcattat
     5281 gcacctccta tgatttttat gggtttcccc gattttttgt gaagactcgc ctagcatcgt
     5341 gggacgaacc acttaaactt gaataatcaa gcaacgatgt tcgtgcggtt gcacaggatc
     5401 gtgcatagtc aactcttcaa gtatagcata tctcctattt tcttacaagt aataacacct
     5461 aaaatgaagc tttttctttt acttttttct gccaagaggc aaaaagcatg ctgaggtaaa
     5521 aaacgctcat cataatagga acaccaagaa tggtcttttc atgatagaaa atcgtcaaat
     5581 aggctgaaaa gacaacgcca aggacaaaac tactaagcag gctaacaaat atgaatcctt
     5641 cacgcaaaaa aggagtgtgc ttggttcgga aataatctcc aaaagccagc atggtccgtt
     5701 tgatattccc tgtcataaaa gcgttattat aggcaatacc cgacacttct ccaaaagcag
     5761 ttgtcaccag tcccatacag aaggccaagg gcggcactag atagatatta tccacagttt
     5821 gcggcacaaa agcaataatg attgataaga ttgccaaggg aatcaaggac agaataggtt
     5881 ttttcacaat tctcaatttt tccttataaa tcgttaataa aaagactccc atcataaacg
     5941 ctagcaaggt gagaaccttg tccctaacat ccgaaacatt atttttaatt aattctactg
     6001 aaagaaagac aacatttcca gtttgtccag ctacaagggt attcccgcga acaataaaag
     6061 tgtaagcatc cacatatcca gcacaaaacg tcaaaaaaag tgctaacctt ttagactgac
     6121 gtgatatttt tcttataggt aataacctca ttttacctcc cattgtattt tctcttagaa
     6181 atattgtacc attttctttc taaaaaatcg taggctacca tttagatttt actattagca
     6241 taaaaataat aatagacaac tatttatcca aaaatagata gatgtaacat gtttgcaaac
     6301 aaagcatacg aacctttagt aaaatcattt ccatgaaact agaatagagc cctcttagca
     6361 aaaatcatta ttttaattta tttctaatca ctccttgaca taaataactc tcaccaataa
     6421 aagactatgt cttaaaaaaa tggtataata aaatcaatac ttgggcttga tggctatgct
     6481 actaataaca attaggagag aaaatcaggc acttgttaac aacaaggatt atccccttga
     6541 gatgaaagga actttagaaa tcttatgatg aacatgcaaa acatgatgcg tcaagcacaa
     6601 aaacttcaaa aacaaatgga acaaagccaa gctgaacttg ctgctatgca atttgttggc
     6661 aaatctgctc aagatcttgt ccaagcgacc ttaactggcg ataagaaagt tgtcagcatt
     6721 gatttcaatc cagctgtcgt tgacccagag gaccttgaga ctctttctga tatgaccgtt
     6781 caagccatca actctgctct tgaacaaatc gatgaaacta ccaagaaaaa actgggtgct
     6841 ttcgctggga aattaccttt ctaaaaacaa ggagctagaa caatgcttgt cgataacaaa
     6901 ggctaagaaa ggtgcaaaaa tgactctata atatttgtag tgggtaaatc ccctatggat
     6961 attatggagc ctatttttgt gtagaaaaaa gtcccatatg acctataatg aaaagcgaca
     7021 aaacaactca ttagaaagaa tcatatggaa caattacatt ttatcacaaa attactagac
     7081 attaaagacc ctaatatcca gattttagac atcgtcaata aggatacaca caaggaaatc
     7141 atcgccaaac tggactatga agctccatct tgtcctgagt gcggaagtca aatgaagaaa
     7201 tatgactttc aaaaaccttc taaaattcct tatcttgaaa caactggtat gcctactaga
     7261 attctcctta gaaagcgtcg tttcaagtgc tatcattgtt ctaaaattat ggttgctgaa
     7321 acttctatcg tcaagaagaa tcatcaaatc cctcgtatca tcaaccaaaa gattgctcaa
     7381 aagttaattg aaaagatttc tatgactgat attgcccatc agctttccat ctcaacttca
     7441 actgtcattc gaaagctcaa tgacttccac tttgagtgta attttagaaa tctgcctaag
     7501 attatgtctt gggacgttga aacagtccgg ggagtgactg tttcaatcgg gagatggaga
     7561 tgagctttat tgcgcaagat tttaacaatc tcaatatcat cactgttctt gaaggtagaa
     7621 cacaagctgt catccgagat cactttctta aatatgatag agccgtccga tgtcgcgtca
     7681 aaatcattac tatggatatg tttagccctt actatgactt ggctaaacag cttcgctttc
     7741 aaatttctag gctcaggctg aaacagtctc ccaggctgtt tcactcccga atgctaaaat
     7801 cgttcttgat cgctttcaca ttgtacaaca tcttagccgt gctatgagtc gtgtgcgtgt
     7861 ccaaatcatg aatcagtttc atcgaaaatc ccatgaatac aaggctatca agcgctactg
     7921 gaaactcatt caacaggata gccgtaaact gagtgataag cgattttatc gtcctatttt
     7981 tcgtatgcac ttaaccaata aagagatttt aaacaagctt ttgagctatt cggaagactt
     8041 gaaacaccac tatcagctct atcaactctt gctttttcac ttccagaata aggaaccaga
     8101 gaaatttttc ggacttattg aggacaatct taagcaggtt catcctattt ttcagactgt
     8161 ctttaaaacc ttcc
//
LOCUS       DAVFER010000068         7717 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1105170250
            SAMEA2167659-rid19724873.denovo.068, whole genome shotgun sequence.
ACCESSION   DAVFER010000068 DAVFER010000000
VERSION     DAVFER010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2167659
            Sequence Read Archive: ERR388902
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7717)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7717)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928716.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928716.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 04:07:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,118
            CDSs (total)                      :: 2,073
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 120
            CDSs (without protein)            :: 120
            Pseudo Genes (ambiguous residues) :: 0 of 120
            Pseudo Genes (frameshifted)       :: 67 of 120
            Pseudo Genes (incomplete)         :: 47 of 120
            Pseudo Genes (internal stop)      :: 34 of 120
            Pseudo Genes (multiple problems)  :: 23 of 120
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7717
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2167659-rid19724873.denovo.068"
                     /strain="1105170250"
                     /db_xref="taxon:1313"
     gene            <1..209
                     /locus_tag="VU534_001972"
     CDS             <1..209
                     /locus_tag="VU534_001972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU1514502.1"
                     /translation="RKSSKLKPLTAEDKAYNHALSKERSKVENIFAKVETFKMFSTTY
                     RNHRKRFGLRMNLIAGIINHELGF"
     gene            complement(947..1207)
                     /locus_tag="VU534_001973"
     CDS             complement(947..1207)
                     /locus_tag="VU534_001973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1514503.1"
                     /translation="MRERSATGAQGLSKSIKKHLNDLTRLTASLLGDEKLSAITSSSA
                     VKADMHRFVIELEPVKSTILQNNDISLDQNEIFEILKNFLDG"
     gene            complement(1266..1817)
                     /locus_tag="VU534_001974"
     CDS             complement(1266..1817)
                     /locus_tag="VU534_001974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001111259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1514504.1"
                     /translation="MPANTKVIFQEMFADFQNYYVLIGGTATSIVLDSQGFKSRTTKD
                     YDMVIIDEVKNKEFYTTLNHFLELGEYQGSQKDEKAQLFRFTTTNPEFPSMIELFSIL
                     PEYPLKKDGREIPLHFDQDASLSALLLDEDYYNILVHEKETIQGYSVLSNCGLYSSKI
                     SSNHVSFHLQPQNSVLSSLQLAS"
     gene            complement(1807..2004)
                     /locus_tag="VU534_001975"
     CDS             complement(1807..2004)
                     /locus_tag="VU534_001975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000890145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1514505.1"
                     /translation="MLEIWKYRPFVSEFWNDFKNNHDKQFVDPISLYLTLKDDDDPRI
                     EEESEALENMILQYLGEDDAS"
     gene            complement(2008..2802)
                     /locus_tag="VU534_001976"
     CDS             complement(2008..2802)
                     /locus_tag="VU534_001976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001101215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1514506.1"
                     /translation="MNVKKIMSIFQSFYVDVSIEELTLTLPISFVKRFEYTQMTFHKE
                     SFLLIKEKRRGSLSSFVTQARTMGEKANMDVVLVFSKLSDSEKKQLLQARVPFVDFKG
                     NLFFPPLGLVLNANDTEVPKELTPSEQLTWIAFLLTKGQKVVDVDLLSQVTGLPNSTI
                     YRCLRTFKALYWLNKQNKLYTYTVSKKELFLKSVSCLFNPIKKRILLPDGDIKQIKSV
                     SNLLYGGAYALSHSTFLAETDENISYVIWQRKFNQLSLPLSQHVLK"
     gene            complement(3210..3635)
                     /locus_tag="VU534_001977"
     CDS             complement(3210..3635)
                     /locus_tag="VU534_001977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000204059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1514507.1"
                     /translation="MTSRVFIDADCISVFLWVGTEHLLEKLYLGKIVIPQEVYDEINI
                     PTIPHLKSRIDQLVAKGSAEIVSIDIGTEEYALYRDLTRNHDSNKIIGKGEGASISLA
                     KKHNGILGSNNLRDVKSYVEEFSLEYMTTGDILIEAFKA"
     gene            complement(3764..4123)
                     /locus_tag="VU534_001978"
     CDS             complement(3764..4123)
                     /locus_tag="VU534_001978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1514508.1"
                     /translation="MKKSSVSLILIGEGDETERKADQFASYFLIFPSSLYRMVEEIRE
                     NANRTHLEVEDIIKLGQFYGISHKAMLYRLRNDGYLDAEEIKNMDISVIETASRLGYD
                     TSLYRPLSESKKEMALG"
     gene            complement(4169..4375)
                     /locus_tag="VU534_001979"
     CDS             complement(4169..4375)
                     /locus_tag="VU534_001979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000366086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1514509.1"
                     /translation="MDLSNKASNLRKKLGADGESPIDIFKLVQKIENLTLVFYGLGKN
                     ISGVCYKGTQFSLIAVNSDMPLGR"
     gene            complement(4362..4523)
                     /locus_tag="VU534_001980"
     CDS             complement(4362..4523)
                     /locus_tag="VU534_001980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000289348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU1514510.1"
                     /translation="MYVINVCDVGKRIKELRISSNLTQDKIAEYLSLNQSMIAKMEKG
                     ERNITNGFK"
     gene            complement(4881..5837)
                     /gene="lytA"
                     /locus_tag="VU534_001981"
     CDS             complement(4881..5837)
                     /gene="lytA"
                     /locus_tag="VU534_001981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase LytA"
                     /protein_id="HEU1514511.1"
                     /translation="MEINVSKLRTDLPQVGVQPYRQVHAHSTGNPHSTVQNEADYHWR
                     KDPELGFFSHIVGNGCIMQVGPVDNGAWDVGGGWNAETYAAVELIESHSTKEEFMTDY
                     RLYIELLRNLADEAGLPKTLDTGSLAGIKTHEYCTNNQPNNHSDHVDPYPYLAKWGIS
                     REQFKHDIENGLTIETGWQKNDTGYWYVHSDGSYPKDKFEKINGTWYYFDSSGYMLAD
                     RWRKHTDGNWYWFDNSGEMATGWKKIADKWYYFNEEGAMKTGWVKYKDTWYYLDAKEG
                     AMVSNAFIQSADGTGWYYLKPDGTLADKPEFTVEPDGLITVK"
     gene            complement(6213..7583)
                     /locus_tag="VU534_001982"
     CDS             complement(6213..7583)
                     /locus_tag="VU534_001982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HEU1514512.1"
                     /translation="MNKKRTVDLIHGPILPSLLSFTFPILLSNIFQQLYNTADVLIVG
                     RFLGQESLAAVGATTAIFDLIVGFTLGVGNGMGIVIARYYGARNFTKIKEAVAATWIL
                     GALLSILVMLLGFLGLYPLLQYLDTPAEILPQSYQYISMIVTCVGVSFAYNLFAGLLR
                     SIGDSLAALGFLIFSALVNVVLDLYFITQLHLGVQSAGLATIISQGLSAVLCFYYIRK
                     SVPELLPQFKHFKWDKSLYADLLEQGLAMGLMSSIVSIGSVILQFSVNTFGAVIISAQ
                     TAARRIMTFALLPMTAISASMTTFASQNLGAKRPDRIVQGLRIGSRLSISWAVFVCIF
                     LFFASPALVSFLASSTDGYLIENGSLYLQISSTFYPILSLLLIYRNCLQGLGQKILPL
                     VSSFIELIGKIVFVVLIIPWAGYKGVILCEPLIWVAMTVQLYFSLFRHPLIKEGKAIL
                     ATKVQS"
BASE COUNT         2496 a         1579 c         1220 g         2422 t
ORIGIN      
        1 cacgtaaatc cagcaaactc aagccgctaa cagctgaaga taaagcctat aaccatgcgc
       61 tatctaagga gagaagcaag gttgagaaca tctttgccaa agtagaaacg tttaaaatgt
      121 tttcaacaac ctatcgaaat catcgtaaac gctttggatt acgaatgaat ttgattgctg
      181 gtattatcaa tcatgaacta ggattctagt tttgcaggaa gtctattata tatgcacaga
      241 catatgaaat ctttttgaga tagcagttat gatatattta tccattcaca acatcttctg
      301 taccaatact acaatattgg tacattttga ttacacaatc gtttcaaaaa atatgatgga
      361 agcctgagta ttttatagta actcccttcc tatcaactag atcaaccagt tgagtgttga
      421 atgttgaaac accctagcct cagcaaagga ctatgagcag catttcctag ctaataggac
      481 gctccaaatc acctattcta aatccatcac tagcttggtc agtaagatac agactgcaag
      541 gcaagactga cgtggttgat gagattttgg aagagtatta caatcataga ttcaccagta
      601 gacttgaccg cagatttaac tatagtagat tgaaactaga atagtacact tctgcttcta
      661 aaacattgtt agaaatcgat ttgactgtcc tgatcaattt gtcctgttct cgtttcattc
      721 tactatacta aaaaaccacc tgaaacaaat caagtgacta gaggataaaa acgaagactg
      781 ggcaaaaagt tttgaaaagc aaaaaacgca taatatcagg tcttgaaaaa ccttgatact
      841 atacgtttga ttgtgggaag attgacttca ttttctcctg aaattgaagt tttttctagt
      901 ttccagatat agacgaattc aatatagcca tctcgctaca attattttaa ccatcgagaa
      961 aatttttcag aatttcaaaa atttcatttt gatccaatga aatgtcatta ttttgaagaa
     1021 tagttgactt cacaggctct aattctatca caaagcggtg catgtctgct tttaccgcac
     1081 tacttgatgt tatagccgat aacttttcat ctcctagcaa ggaagctgtc aaacgggtaa
     1141 ggtcattcaa atgcttttta atggacttac ttaaaccttg agcacctgtg gcagagcgct
     1201 ccctcatatc cagccaagct ttagccttaa aaataattaa tactcaatga aaatcaaaga
     1261 gcaaactagg aagctagctg caggctgctc aaaacactgt tttgaggttg tagatggaag
     1321 ctgacgtggt ttgaagagat tttcgaagag tataaaccac aattactcaa taccgaatac
     1381 ccctgaatgg tttctttttc atgcaccaat atattataat aatcttcatc caataataag
     1441 gctgataaac tagcatcttg gtcaaaatgt aagggaattt ctcgaccgtc cttctttaat
     1501 ggatattctg gtaagatact aaatagttca atcatagaag gaaactcagg attagttgtt
     1561 gtaaatcgaa aaagctgcgc tttctcatct ttctgacttc cttgatactc tcccaattct
     1621 aaaaaatgat tcaaggtagt ataaaattcc ttatttttta cttcatcaat gatgaccata
     1681 tcataatctt ttgttgtgcg acttttaaat ccttgcgaat ccaatacgat agaggtagca
     1741 gttcccccaa tcagaacata atagttctga aaatccgcaa acatttcttg aaaaataact
     1801 ttcgtattag ctggcatcat cttctcccag atactgtaat atcatatttt ctagtgcttc
     1861 actctcttcc tctatacgtg ggtcatcatc atcttttaag gtcaaataaa gagaaatcgg
     1921 atctacaaat tgtttatcat gattattttt aaaatcattc caaaactcag atacaaaagg
     1981 acgatatttc catatctcta gcatctttca ttttaaaaca tgctgagaaa gtggcaagga
     2041 taactgattg aattttctct gccatatgac atagctaata ttttcatccg tttcagctaa
     2101 aaaagttgaa tgcgacaaag cataagcacc accatataga aggttagaaa cagattttat
     2161 ctgctttata tcgccatctg gcaataaaat ccgttttttg atgggattaa ataaacatga
     2221 cacggatttt aagaataatt ctttctttga caccgtatat gtgtaaagct tattttgctt
     2281 gtttaaccaa tataaagctt taaaagtcct caaacaccta taaattgttg agtttggaag
     2341 tccagtgact tgtgaaagca aatcaacatc tactactttt tgaccttttg tcaataaaaa
     2401 ggcaatccac gttaattgtt cgctaggtgt taattcctta gggacttcag tatcattcgc
     2461 attgagtact agtcccaatg gagggaagaa gaggtttccc ttaaagtcta caaacggaac
     2521 tctagcttga agtaattgct ttttttcact gtctgataac ttcgaaaaca ccaaaacaac
     2581 atccatattg gctttttcac ccatagtgcg agcctgagta acaaatgaac tcaaactccc
     2641 ccttctcttt tctttaatca ataaaaatga ttccttatga aaagtcattt gagtatactc
     2701 aaaccttttt acaaaactga ttggtaaagt caaagtcagt tcctcaatac tgacatcaac
     2761 ataaaaggat tgaaaaattg acattatctt tttgacattc atgttttttc cttattctat
     2821 catttttatt atattttatc attcggtata ataaaatata agttttttga taaaataacc
     2881 aaaaactact cgctatcccc tctcacatta ccctacatat cgtttgacat gcgactgata
     2941 gttcaggaaa acttcaagga gaacttttct ctcatccact atgcaggact tactatttca
     3001 cttctactcc tataggctca atttgacact tttctttttc gaattgctca tatgcctcct
     3061 gaatagtgag ttcgatttat ccaaatttat ttttgtctat tttgatgaat acttccacga
     3121 agatagtctg aaaatgaatt tgcaccaatt ttccttctct ttttaagcat attattccag
     3181 atatgattgc cctcttattc agtaataaat tacgctttaa acgcttcaat cagtatatct
     3241 cctgttgtca tatattctaa agaaaattct tctacatatg atttaacatc tcttaggtta
     3301 ttacttccta atatcccatt atgctttttc gctaaggaaa tagatgcccc ttctccctta
     3361 ccaataatct tgttactatc atgatttctt gttaaatctc tatataatgc gtattcttca
     3421 gttccaatgt ctatgctcac aatctcagct gaacccttag ctaccaactg atctatccta
     3481 gattttaaat ggggaattgt aggtatattg atttcatcat acacctcttg tggaataaca
     3541 attttaccca aatagagctt ttctaaaaga tgttcagtgc caacccataa aaatactgaa
     3601 atacaatctg catcaataaa tacacgacta gtcaaacgac aactcccccc tcttcatcta
     3661 gcccatatac aatatcatat ctgaaagcat ctagtaacag ttcctcatac ttcccttgcg
     3721 aaattctgtt attttctaaa agttgttcag ttgaattaat atattatcct aatgccattt
     3781 cttttttact ttctgacaaa ggacgatata aacttgtatc atagcctaat cttgaagctg
     3841 tctctataac actaatatcc atatttttaa tttcttctgc atcaaggtat ccatcattcc
     3901 tcaatctata taacatagct ttatgactga taccataaaa ctgacccaat tttataatat
     3961 cttctacttc aagatgagtt ctattggcat tttctctgat ttcctcaacc atcctataca
     4021 gtgaagatgg gaaaattaaa aaataagaag caaactgatc cgcttttctt tcagtttcat
     4081 ctccttcacc aatcaagata agactgactg aactcttctt cacctcatca taataaagat
     4141 gatacagtcc atgtgctaaa gaaaatcttt accttcctaa tggcatgtct gaattgactg
     4201 caatgagact gaactgagtt cctttataac agactccgct aatattcttt ccgagtccat
     4261 aaaataccag cgtcaaattt tctatctttt gtaccaattt aaaaatatct atcggcgatt
     4321 caccatcagc tcccaacttt tttctaagat ttgaagcttt attacttaaa tccattcgtg
     4381 atattccttt cacctttttc cattttggca atcatgcttt gattcaaaga caaatactca
     4441 gcaatcttat cttgagtaag atttgaagat attctaagtt cttttattct ttttccaaca
     4501 tcacatacat ttatcacata catttatcat attcatacac ctctcataaa aagaatagca
     4561 cactcttgtc ataatttttt aaataaaaaa attatgacaa aacaaggaag caatttattg
     4621 atgctgctta aaaatctaaa attgatgagt tcctatcaaa aatcgtatct tcaacctcaa
     4681 aacagtactt aaagctatcc gactcggttt acattgtcaa atttagattt tatttgagca
     4741 taactttcta gtttgctttt tgatttttgt ttaatatagt agcaaaattg aaggaaatat
     4801 ctccacaaga aaacgcatac tattaagctt tttcaagacc taataatatg cgctgttctg
     4861 atttgaaaga cattccatta ttattttact gtaatcaagc catctggctc tactgtgaat
     4921 tctggcttgt ctgccagtgt tccgtctggt ttgaggtagt accagcctgt tccgtccgct
     4981 gactggataa aggcatttga taccatggcg ccttctttag cgtctaagta gtaccaagtg
     5041 tccttgtact tgacccagcc tgtcttcatg gcaccttctt cgttgaaata gtaccactta
     5101 tcagcgattt tcttccagcc tgtagccatt tcgcctgagt tgtcgaacca gtaccagttg
     5161 ccgtctgtgt gcttcctcca gcggtctgca agcatatagc ctgaactgtc aaagtagtac
     5221 caagtgccat tgattttctc aaacttgtct tttggataag agccgtctga atgtacgtac
     5281 cagtagccag tgtcattctt ctgccagcct gtttcaatcg tcaagccgtt ctcaatatca
     5341 tgcttaaact gctcacggct aatgccccat ttagcaagat atggataagg gtcaacgtgg
     5401 tctgagtggt tgtttggttg gttattcgtg caatactcgt gcgttttaat tccagctaaa
     5461 ctccctgtat caagcgtttt cggcaaacct gcttcatctg ctagattgcg taagagttcg
     5521 atataaaggc ggtagtccgt catgaactct tctttggttg aatggctttc aatcagttca
     5581 accgctgcat aggtctcagc attccaaccg cccccaacgt cccaggcacc attatcaaca
     5641 ggtcctacct gcatgatgca accgttccca acaatgtgcg agaaaaaacc taattctggg
     5701 tctttccgcc agtgataatc cgcttcattc tgtacggttg aatgcggatt cccagttgag
     5761 tgtgcgtgta cttgcctata tggttgcacg ccgacttgag gcaaatctgt tcttaattta
     5821 ctcacattaa tttccatatt ctactcctta tcaattaaaa caactcattt tttacaatcc
     5881 agaaccagaa actcctttat ttctacctta caaagaagac aatcttagtc acgattaggc
     5941 ttgtagatag aacttcaaaa cgcactattt tgacactgta aataggactg acaaggtctg
     6001 cattctatct acaataacac cccagactaa aaagattttc aaaagtatat ttttacagtc
     6061 tctatatgtc cttttcataa atactatact ttattatatc atataaaaga agtcaaaagt
     6121 ctgttaaact attttcaaca ccaaactaaa gaagagaaca caagtttttt cgattttcac
     6181 tagaggaaat ggattttatt cagtaaatcc aactaggatt gcactttggt tgccaagatt
     6241 gccttgcctt cttttatcaa gggatgacgg aataatgaga agtacagttg aactgtcatg
     6301 gcaacccaga taagaggttc acaaaggata acacccttat atcctgccca aggaataatc
     6361 aaaaccacaa aaacgatttt tccgattagt tcaataaagc tagaaactag aggaaggatc
     6421 ttttgcccca agccctgcaa gcaattgcga taaatcaaca agaggctcaa aatgggataa
     6481 aaggttgaac tgatttgcag atagagactt ccattttcta tcaagtaacc atctgtcgaa
     6541 ctagccaaga aggaaaccaa agctggactg gcaaaaaaga ggaaaataca aacaaaaact
     6601 gcccaggata tacttaaacg actgccgatt cgaagacctt gaacaatacg gtcaggtcgc
     6661 ttagctccta gattctgaga agcaaaggtc gtcattgatg cagaaatagc ggtcatagga
     6721 agaagggcaa aggtcataat gcgtcgagct gccgtctggg cactaataat cactgcacca
     6781 aatgtattaa cagaaaactg taaaatcaca ctgccgatag atacaattga actcatcaag
     6841 cccatagcca aaccttgctc caagagatcc gcgtacaagc ttttgtccca tttgaaatgt
     6901 ttaaactgtg gcaagagttc tggcacactt ttacgaatat aataaaagca gagaaccgct
     6961 gataaacctt gcgaaataat ggtagcaagt cctgcggatt gaactcccag atgcaattgc
     7021 gtaataaaat agagatccag aaccacatta accaaggcag agaaaatcag aaatcccagg
     7081 gctgctagac tgtcaccaat agaccgcaac aagcctgcaa aaagattata agcaaagctg
     7141 acacctacac aggtcacaat catagaaata tattgataag attgaggaag aatttctgca
     7201 ggagtatcta agtattgcaa gagaggatac aagccaagaa agcccagcaa cataactaga
     7261 atgctcaaaa gagcacctaa aatccaggtg gctgctactg cttccttgat tttagtgaaa
     7321 ttccgagccc cataataacg agcaatgaca atccccatgc cattgccaac accaagtgta
     7381 aaacctacaa tcaggtcaaa aatcgctgtc gtcgctccta ctgcagccaa ggattcttga
     7441 ccaagaaatc gtccaacaat caagacatca gcagtgttat agagctgttg aaaaatattt
     7501 gatagcaaaa ttggaaaggt gaagcttaag agcgagggaa gaatcggacc atgtatcagg
     7561 tccactgttc gttttttatt cataaagcta ttatatcagc tttccagagg agcgacaaga
     7621 aacagcaaac tatatatagc ggaatgaaat aaggaaagtc aaatcgattt ttaacaatgt
     7681 tttagaagta gatatgtact attctagttt cgatcta
//
LOCUS       DAVFER010000069         6996 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1105170250
            SAMEA2167659-rid19724873.denovo.069, whole genome shotgun sequence.
ACCESSION   DAVFER010000069 DAVFER010000000
VERSION     DAVFER010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2167659
            Sequence Read Archive: ERR388902
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6996)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6996)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928716.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928716.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 04:07:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,118
            CDSs (total)                      :: 2,073
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 120
            CDSs (without protein)            :: 120
            Pseudo Genes (ambiguous residues) :: 0 of 120
            Pseudo Genes (frameshifted)       :: 67 of 120
            Pseudo Genes (incomplete)         :: 47 of 120
            Pseudo Genes (internal stop)      :: 34 of 120
            Pseudo Genes (multiple problems)  :: 23 of 120
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6996
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2167659-rid19724873.denovo.069"
                     /strain="1105170250"
                     /db_xref="taxon:1313"
     gene            282..6704
                     /locus_tag="VU534_001983"
     CDS             282..6704
                     /locus_tag="VU534_001983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HEU1514513.1"
                     /translation="MKKSTVLSLTTAAVILAAYAPNEVVLADTSSSEDALNISDKEKV
                     AENKEKHENIHSAMETSQDFKEKKTAVIKEKEVVSKNPVIDNNTSNEEAKIKEENSNK
                     SQGDYTDSFVNKNTENPKKEDKVVYIAEFKDKESGEKAIKELSSLKNTKVLYTYDRIF
                     NGSAIETTPDNLDKIKQIEGISSVERAQKVQPMMNHARKEIGVEEAIDYLKSINAPFG
                     KNFDGRGMVISNIDTGTDYRHKAMRIDDDAKASMRFKKEDLKGTDKNYWLSDKIPHAF
                     NYYNGGKITVEKYDDGRDYFDPHGMHIAGILAGNDTEQDIKNFNGIDGIAPNAQIFSY
                     KMYSDAGSGFAGDETMFHAIEDSIKHNVDVVSVSSGFTGTGLVGEKYWQAIRALRKAG
                     IPMVVATGNYATSASSSSWDLVANNHLKMTDTGNVTRTAAHEDAIAVASAKNQTVEFD
                     KVNIGGESFKYRNIGAFFDKSKITTNEDGTKAPSKLKFVYIGKGQDQDLIGLDLRGKI
                     AVMDRIYTKDLKNAFKKAMDKGARAIMVVNTVNYYNRDNWTELPAMGYEADEGTKSQV
                     FSISGDDGVKLWNMINPDKKTEVKRNNKEDFKDKLEQYYPIDMESFNSNKPNVGDEKE
                     IDFKFAPDTDKELYKEDIIVPAGSTSWGPRIDLLLKPDVSAPGKNIKSTLNVINGKST
                     YGYMSGTSMATPIVAASTVLIRPKLKEMLERPVLKNLKGDDKIDLTSLTKIALQNTAR
                     PMMDATSWKEKSQYFASPRQQGAGLINVANALRNEVVATFKNTDSKGLVNSYGSISLK
                     EIKGDKKYFTIKLHNTSNRPLTFKVSASAITTDSLTDRLKLDETYKDEKSPDGKQIVP
                     EIHPEKVKGANITFEHDTFTIGANSSFDLNAVINVGEAKNKNKFVESFIHFESVEEME
                     ALNSNGKKINFQPSLSMPLMGFAGNWNHEPILDKWAWEEGSRSKTLGGYDDDGKPKIP
                     GTLNKGIGGEHGIDKFNPAGVIQNRKDKNTTSLDQNPELFAFNNEGINAPSSSGSKIA
                     NIYPLDSNGNPQDAQLERGLTPSPLVLRSAEEGLISIVNTNKEGENQRDLKVISREHF
                     IRGILNSKSNDAKGIKSSKLKVWGDLKWDGLIYNPRGREENAPESKDNQDPATKIRGQ
                     FEPIAEGQYFYKFKYRLTKDYPWQVSYIPVKIDNTAPKIVSVDFSNPEKIKLITKDTY
                     HKVKDQYKNETLFARDQKEHPEKFDEIANEVWYAGAALVNEDGEVEKNLEVTYAGEGQ
                     GRNRKLDKDGNTIYEIKGAGDLRGKIIEVIALDGSSNFTKIHRIKFANQADEKGMISY
                     YLVDPDQDSSKYQKLGEIAESKFKNLGNGKEGSLKKDTTGVEHHHQENEESIKEKSSF
                     TIDRNISTIRDFENKDLKKLIKKKFREVDDFTSETGKRMEEYDYKYDDKGNIIAYDDG
                     TDLEYETEKLDEIKSKIYGVLSPSKDGHFEILGKISNVSKNAKVYYGNNYKSIEIKAT
                     KYDFHSKTMTFDLYANINDIVDGLAFAGDMRLFVKDNDQKKAEIKIRMPEKIKETKSE
                     YPYVSSYGNVIELGEGDLSKNKPDNLTKMESGKIYSDSEKQQYLLKDNIILRKGYALK
                     VTTYNPGKTDMLEGNGVYSKEDIAKIQKANPNLRALSETTIYADSRNVEDGRSTQSVL
                     MSALDGFNIIRYQVFTFKMNDKGEAIDKDGNLVTDSSKLVLFGKDDKEYTGEDKFNVE
                     AIKEDGSMLFIDTKPVNLSMDKNYFNPSKSNKIYVRNPEFYLRGKISDKGGFNWELRV
                     NESVVDNYLIYGDLHIDNTRDFNIKLNVKDGDIMDWGMKDYKANGFPDKVTDMDGNVY
                     LQTGYSDLNAKAVGVHYQFLYDNVKPEVNIDPKGNTSIEYADGKSVVFNINDKRNNGF
                     DGEIQEQHIYINGKEYTSFNDIKQIIDKTLNIKIVVKDFARNTTVKEFILNKDTGEVS
                     ELKPHRVTVTIQNGKEMSSTIVSEEDFILPVYKGELEKGYQFDGWEISGFEGKKDAGY
                     VINLSKDTFIKPVFKKIEEKKEEENKPTFDVSKKKDNPQVNHSQLNESHRKEDLQREE
                     HSQKSDSTKDVTATVLDKNNISSKSTTNNPNKLPKTGTASGAQTLLAAGIMFIVGIFL
                     GLKKKNQD"
BASE COUNT         2750 a          935 c         1349 g         1962 t
ORIGIN      
        1 tgttttgagc aatctgcggc tagtttccta gtttgctctt tgattttcat tgagtactaa
       61 tcttattttt taatgtgtgc taaaaaataa attaactaat gttaattttt ttgacttaaa
      121 tttttttaaa tgatatactg tttttataga gagataacaa ttatatataa atgtactact
      181 ctatttccta gataatactt agtaaaactt tttataacaa aggctagcaa agttaaagtt
      241 tattatctat tggaagttat ataaatatgt aaggaattaa aatgaaaaaa agtacagtat
      301 tgtcattaac cacagctgca gttattttag cagcctatgc ccctaatgag gtagtcttag
      361 cagacacatc tagctctgaa gatgctttaa acatctctga taaagaaaaa gtagcagaaa
      421 ataaagagaa acatgaaaat atccatagtg ctatggaaac ttcacaggat tttaaagaga
      481 agaaaacagc agtcattaag gaaaaagaag ttgttagtaa aaatcctgtg atagacaata
      541 acactagcaa tgaagaagca aaaatcaaag aagaaaattc caataaatcc caaggagatt
      601 atacggactc atttgtgaat aaaaacacag aaaatcccaa aaaagaagat aaagttgtct
      661 atattgctga atttaaagat aaagaatctg gagaaaaagc aatcaaggaa ctatccagtc
      721 ttaagaatac aaaagtttta tatacttatg atagaatttt taacggtagt gccatagaaa
      781 caactccaga taacttggac aaaattaaac aaatagaagg tatttcatcg gttgaaaggg
      841 cacaaaaagt ccaacccatg atgaatcatg ccagaaagga aattggagtt gaggaagcta
      901 ttgattacct aaagtctatc aatgctccgt ttgggaaaaa ttttgatggt agaggtatgg
      961 tcatttcaaa tatcgatact ggaacagatt atagacataa ggctatgaga atcgatgatg
     1021 atgccaaagc ctcaatgaga tttaaaaaag aagacttaaa aggcactgat aaaaattatt
     1081 ggttgagtga taaaatccct catgcgttca attattataa tggtggcaaa atcactgtag
     1141 aaaaatatga tgatggaagg gattattttg acccacatgg gatgcatatt gcagggattc
     1201 ttgctggaaa tgatactgaa caagacatca aaaactttaa cggcatagat ggaattgcac
     1261 ctaatgcaca aattttctct tacaaaatgt attctgacgc aggatctggg tttgcgggtg
     1321 atgaaacaat gtttcatgct attgaagatt ctatcaaaca caacgttgat gttgtttcgg
     1381 tatcatctgg ttttacagga acaggtcttg taggtgagaa atattggcaa gctattcggg
     1441 cattaagaaa agcaggcatt ccaatggttg tcgctacggg taactatgcg acttctgctt
     1501 caagttcttc atgggattta gtagcaaata atcatctgaa aatgaccgac actggaaatg
     1561 taacacgaac tgcagcacat gaagatgcga tagcggtcgc ttctgctaaa aatcaaacag
     1621 ttgagtttga taaagttaac ataggtggag aaagttttaa atacagaaat ataggggcct
     1681 ttttcgataa gagtaaaatc acaacaaatg aagatggaac aaaagctcct agtaaattaa
     1741 aatttgtata tataggcaag gggcaagacc aagatttgat aggtttggat cttaggggca
     1801 aaattgcagt aatggataga atttatacaa aggatttaaa aaatgctttt aaaaaagcta
     1861 tggataaggg tgcacgcgcc attatggttg taaatactgt aaattactac aatagagata
     1921 attggacaga gcttccagct atgggatatg aagcggatga aggtactaaa agtcaagtgt
     1981 tttcaatttc aggagatgat ggtgtaaagc tatggaacat gattaatcct gataaaaaaa
     2041 ctgaagtcaa aagaaataat aaagaagatt ttaaagataa attggagcaa tactatccaa
     2101 ttgatatgga aagttttaat tccaacaaac cgaatgtagg tgacgaaaaa gagattgact
     2161 ttaagtttgc acctgacaca gacaaagaac tctataaaga agatatcatc gttccagcag
     2221 gatctacatc ttgggggcca agaatagatt tacttttaaa acccgatgtt tcagcacctg
     2281 gtaaaaatat taaatccacg cttaatgtta ttaatggcaa atcaacttat ggctatatgt
     2341 caggaactag tatggcgact ccaatcgtgg cagcttctac tgttttgatt agaccgaaat
     2401 taaaggaaat gcttgaaaga cctgtattga aaaatcttaa gggagatgac aaaatagatc
     2461 ttacaagtct tacaaaaatt gccctacaaa atactgcgcg acctatgatg gatgcaactt
     2521 cttggaaaga aaaaagtcaa tactttgcat cacctagaca acagggagca ggcctaatta
     2581 atgtggccaa tgctttgaga aatgaagttg tagcaacttt caaaaacact gattctaaag
     2641 gtttggtaaa ctcatatggt tccatttctc ttaaagaaat aaaaggtgat aaaaaatact
     2701 ttacaatcaa gcttcacaat acatcaaaca gacctttgac ttttaaagtt tcagcatcag
     2761 cgataactac agattctcta actgacagat taaaacttga tgaaacatat aaagatgaaa
     2821 aatctccaga tggtaagcaa attgttccag aaattcaccc agaaaaagtc aaaggagcaa
     2881 atatcacatt tgagcatgat actttcacta taggcgcaaa ttctagcttt gatttgaatg
     2941 cggttataaa tgttggagag gccaaaaaca aaaataaatt tgtagaatca tttattcatt
     3001 ttgagtcagt ggaagaaatg gaagctctaa actccaacgg gaagaaaata aacttccaac
     3061 cttctttgtc gatgcctcta atgggatttg ctgggaattg gaaccacgaa ccaatccttg
     3121 ataaatgggc ttgggaagaa gggtcaagat caaaaacact gggaggttat gatgatgatg
     3181 gtaaaccgaa aattccagga accttaaata agggaattgg tggagaacat ggtatagata
     3241 aatttaatcc agcaggagtt atacaaaata gaaaagataa aaatacaaca tccctggatc
     3301 aaaatccaga attatttgct ttcaataacg aagggatcaa cgctccatca tcaagtggtt
     3361 ctaagattgc taacatttat cctttagatt caaatggaaa tcctcaagat gctcaacttg
     3421 aaagaggatt aacaccttct ccacttgtat taagaagtgc agaagaagga ttgatttcaa
     3481 tagtaaatac aaataaagag ggagaaaatc aaagagactt aaaagtcatt tcgagagaac
     3541 actttattag aggaatttta aattctaaaa gcaatgatgc aaagggaatc aaatcatcta
     3601 aactaaaagt ttggggtgac ttgaagtggg atggactcat ctataatcct agaggtagag
     3661 aagaaaatgc accagaaagt aaggataatc aagatcctgc tactaagata agaggtcaat
     3721 ttgaaccgat tgcggaaggt caatatttct ataaatttaa atatagatta actaaagatt
     3781 acccatggca ggtttcctat attcctgtaa aaattgataa caccgcccct aagattgttt
     3841 cggttgattt ttcaaatcct gaaaaaatta agttgattac aaaggatact tatcataagg
     3901 taaaagatca gtataagaat gaaacgctat ttgcgagaga tcaaaaagaa catcctgaaa
     3961 aatttgacga gattgcgaac gaagtttggt atgctggcgc cgctcttgtt aatgaagatg
     4021 gagaggttga aaaaaatctt gaagtaactt acgcaggtga gggtcaagga agaaatagaa
     4081 aacttgataa agacggaaat accatttatg aaattaaagg tgcgggagat ttaaggggaa
     4141 aaatcattga agtcattgca ttagatggtt ctagcaattt cacaaagatt catagaatta
     4201 aatttgctaa tcaggctgat gaaaagggga tgatttccta ttatctagta gatcctgatc
     4261 aagattcatc taaatatcaa aagcttggcg agattgcaga atctaaattt aaaaatttag
     4321 gaaatggaaa agagggtagt ctaaaaaaag atacaactgg ggtagaacat catcatcaag
     4381 aaaatgaaga gtctattaaa gaaaaatcta gttttactat tgatagaaat atttcaacaa
     4441 ttagagactt tgaaaataaa gacttaaaga aactcattaa aaagaaattt agagaagttg
     4501 atgattttac aagtgaaact ggtaagagaa tggaggaata cgattataaa tacgatgata
     4561 aaggaaatat aatagcctac gatgatggga ctgatctaga atatgaaact gagaaacttg
     4621 acgaaatcaa atcaaaaatt tatggtgttc taagtccgtc taaagatgga cactttgaaa
     4681 ttcttggaaa gataagtaat gtttctaaaa atgccaaggt atattatggg aataactata
     4741 aatctataga aatcaaagcg accaagtatg atttccactc aaaaacgatg acatttgatc
     4801 tatacgctaa tattaatgat attgtggatg gattagcttt tgcaggagat atgagattat
     4861 ttgttaaaga taatgatcag aaaaaagctg aaattaaaat tagaatgcct gaaaaaatta
     4921 aggaaactaa atcagaatat ccctatgtat caagttatgg gaatgtcata gaattagggg
     4981 aaggagatct ttcaaaaaac aaaccagaca atttaactaa aatggaatct ggtaaaatct
     5041 attctgattc agaaaaacaa caatatctgt taaaggataa tatcattcta agaaaaggct
     5101 atgcactaaa agtgactacc tataatcctg gaaaaacgga tatgttagaa ggaaatggag
     5161 tctatagcaa ggaagatata gcaaaaatac aaaaggccaa tcctaatcta agagcccttt
     5221 cagaaacaac aatttatgct gatagtagaa atgttgaaga tggaagaagt acccaatctg
     5281 tattaatgtc ggctttggac ggctttaaca ttataaggta tcaagtgttt acatttaaaa
     5341 tgaacgataa aggggaagct atcgataaag acggaaatct tgtgacagat tcttctaaac
     5401 ttgtattatt tggtaaggat gataaagaat acactggaga ggataagttc aatgtagaag
     5461 ctataaaaga agatggctcc atgttattta ttgataccaa accagtaaac ctttcaatgg
     5521 ataagaacta ctttaatcca tctaaatcta ataaaattta tgtacgaaat ccagaatttt
     5581 atttaagagg taagatttct gataagggtg gttttaactg ggaattgaga gttaatgaat
     5641 cggttgtaga taattattta atctacggag atttacacat tgataacact agagatttta
     5701 atattaagct gaatgttaaa gacggtgaca tcatggactg gggaatgaaa gactataaag
     5761 caaacggatt tccagataag gtaacagata tggatggaaa tgtttatctt caaactggct
     5821 atagcgattt gaatgctaaa gcagttggag tccactatca gtttttatat gataatgtta
     5881 aacccgaagt aaacattgat cctaagggaa atactagtat cgaatatgct gatggaaaat
     5941 ctgtagtctt taacatcaat gataaaagaa ataatggatt cgatggtgag attcaagaac
     6001 aacatattta tataaatgga aaagaatata catcatttaa tgatattaaa caaataatag
     6061 acaagacact aaacattaag attgttgtaa aagattttgc aagaaataca accgtaaaag
     6121 aattcatttt aaataaagat acgggagagg taagtgaatt aaaacctcat agggtaactg
     6181 tgaccattca aaatggaaaa gaaatgagtt caacgatagt gtcggaagaa gattttattt
     6241 tacctgttta taagggtgaa ttagaaaaag gataccaatt tgatggttgg gaaatttctg
     6301 gtttcgaagg taaaaaagac gctggctatg ttattaatct atcaaaagat acctttataa
     6361 aacctgtatt caagaaaata gaggagaaaa aggaggaaga aaataaacct acttttgatg
     6421 tatcgaaaaa gaaagataac ccacaagtaa accatagtca attaaatgaa agtcacagaa
     6481 aagaggattt acaaagagaa gagcattcac aaaaatctga ttcaactaag gatgttacag
     6541 ctacagttct tgataaaaac aatatcagta gtaaatcaac tactaacaat cctaataagt
     6601 tgccaaaaac tggaacagca agcggagccc agacactatt agctgccgga ataatgttta
     6661 tagtaggaat ttttcttgga ttgaagaaaa aaaatcaaga ttaagataaa agctatagaa
     6721 aaaaatggtt tatgtactga gattagatag tgaggtgatg acatagtttt gtgaaaatag
     6781 ccatttataa ctcaattatt tagtttactt tactttacta gtgatactat ttggagttat
     6841 taatggactt agtttatata actaatgaat tgattgaaag ggttagtatt gacaatattg
     6901 gtcatattga ctagaaaata gagtctatca aaatttaaag gctaatagag gtgatgagac
     6961 aatttcggct ctttgtcaac tgtagtgggt tgaagt
//
LOCUS       DAVFER010000070         6547 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1105170250
            SAMEA2167659-rid19724873.denovo.070, whole genome shotgun sequence.
ACCESSION   DAVFER010000070 DAVFER010000000
VERSION     DAVFER010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2167659
            Sequence Read Archive: ERR388902
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6547)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6547)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928716.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928716.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 04:07:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,118
            CDSs (total)                      :: 2,073
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 120
            CDSs (without protein)            :: 120
            Pseudo Genes (ambiguous residues) :: 0 of 120
            Pseudo Genes (frameshifted)       :: 67 of 120
            Pseudo Genes (incomplete)         :: 47 of 120
            Pseudo Genes (internal stop)      :: 34 of 120
            Pseudo Genes (multiple problems)  :: 23 of 120
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6547
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2167659-rid19724873.denovo.070"
                     /strain="1105170250"
                     /db_xref="taxon:1313"
     gene            <1..102
                     /locus_tag="VU534_001984"
     CDS             <1..102
                     /locus_tag="VU534_001984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HEU1514514.1"
                     /translation="VPQPVQSGDMVRALKEGLINLYKEDGTSVTVRA"
     gene            437..1171
                     /locus_tag="VU534_001985"
     CDS             437..1171
                     /locus_tag="VU534_001985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001220485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU1514515.1"
                     /translation="MRIKEKTNNINGGIKNVSKHYGHSIILKDINFALNKGEIVGLAG
                     RNGVGKSTLMKILVQNNQPTSGNIISSDNVGYLIEEPKLFLSKTGLENLKYLSNLYGV
                     DYNQERFRCLIQELDLTQSINKKVKTYSLGTKQKLALLLTLVTEPDILILDEPTNGLD
                     IESSQIVLAVLKKLALHENVGILISSHKLEDIEEICERVLFLENGLLTFQKVGKDSHN
                     FLFEIAFSSATDRDIFITKQEFWDIV"
     gene            1331..1811
                     /locus_tag="VU534_001986"
                     /pseudo
     CDS             1331..1811
                     /locus_tag="VU534_001986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863700.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            2196..2405
                     /locus_tag="VU534_001987"
     CDS             2196..2405
                     /locus_tag="VU534_001987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013670190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU1514516.1"
                     /translation="MAKNLKLKLARVERDLTQGQLAEAVGVTRQTIGLIEAGKYNPSL
                     SLCQSICRCLGKTLDQLFWEEEDEK"
     gene            2395..2883
                     /locus_tag="VU534_001988"
     CDS             2395..2883
                     /locus_tag="VU534_001988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000797183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1514517.1"
                     /translation="MKNRFYYSQLLDEREEQLFNKAGSESFYICIALSLLSYIISVLA
                     PSLFNSNMLLIVIIIGTFYFFNRARYLGVTYYGRFHFTILGCFFLTLAITALLMLQNY
                     QFNIEIYQHNPLNFKYLSAWVITYIIYLPWIFIGNLGLKSYGEWAQKKFEQDMDELES
                     GE"
     gene            2999..4459
                     /locus_tag="VU534_001989"
     CDS             2999..4459
                     /locus_tag="VU534_001989"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HEU1514518.1"
                     /translation="MYPDDSLTLHTDLYQINMMQVYFDQGIHNKKAVFEVYFRQQPFK
                     NGYAVFAGLERIVNYLEDLRFSDSDIAYLESLGYHGAFLDYLRNFKLELTVRSAQEGD
                     LVFANEPIVQVEGPLAQCQLVETALLNIVNYQTLVATKAARIRSVIEDEPLMEFGTRR
                     AQEMDAAIWGTRAAVIGGANGTSNVRAGKLFDIPVLGTHAHALVQVYGNDYEAFKAYA
                     ATHKNCVFLVDTYDTLRIGVPAAIQVARELGDQINFMGVRIDSGDIAYISKKVRQQLD
                     EAGFTEAKIYASNDLDENTILNLKMQKAKIDVWGVGTKLITAYDQPALGAVYKIVAIE
                     DETGQMRNTIKLSNNAEKVSTPGKKQVWRITSREKGKSEGDYITYDGVDISDMTEIKM
                     FHPTYTYIKKTVRNFDAVPLLVDIFKEGILVYNLPSLTDIQDYARKEFDKLWDEYKRV
                     LNPQHYPVDLARDVWQDKMDLIDKMRKEALGEGEEE"
     gene            4456..5280
                     /gene="nadE"
                     /locus_tag="VU534_001990"
     CDS             4456..5280
                     /gene="nadE"
                     /locus_tag="VU534_001990"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HEU1514519.1"
                     /translation="MSLQETIIQELGVKPVIDAQEEIRRSIDFLKRYLKKHPFLKTFV
                     LGISGGQDSTLAGRLAQLAMEELRAETGDDSYKFIAVRLPYGVQADEADAQKALAFIQ
                     PDVSLVVNIKESADAMTAAVEATGSPVSDFNKGNIKARCRMIAQYALAGSHSGAVIGT
                     DHAAENITGFFTKFGDGGADILPLYRLNKRQGKQLLQKLGAEPALYEKIPTADLEEDK
                     PGLADEVALGVTYAEIDDYLEGKTISPEAQATIENWWHKGQHKRHLPITVFDDFWE"
     gene            5630..6181
                     /locus_tag="VU534_001991"
     CDS             5630..6181
                     /locus_tag="VU534_001991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU1514520.1"
                     /translation="MKSIGTQILQTERLILRRFVESDAEAMFQNWASSAENLTYVTWD
                     PHPDVEITRNSICNWVASYTNLNYYKWAICLKENPEQVIGDISIVKIDEADLSCEIGY
                     VLGKAYWGNGMMTETLKAILDFCFTQAGFQKVRARYASLNPASGRVMEKAGMSYLQTI
                     VNGVERKGYLADLIYYGISREEC"
BASE COUNT         2067 a         1085 c         1373 g         2022 t
ORIGIN      
        1 gtcccacaac ctgttcaatc aggagacatg gttcgagctc ttaaagaggg gcttatcaat
       61 ctttataagg aagatggaac cagcgtcaca gttcgtgctt aatgtagttg tttagtttta
      121 aaaaactatg caaagctcca tatacaacac ttaaacgaga ttaaagaatg gcgaaatccc
      181 ttgatgcgca agagattagc tgtctttttt attttttaag tgataaagtc ggagtttagg
      241 catcaaagcc tatcaaatta aacaaagaag cgatgtctta gatattttga aaaaaattaa
      301 taagcagaaa actctctatt attttgttgt agagagtttt ttgttaataa aatttcacaa
      361 aatgacattt atatattgca ttaagttaga tatatgatat aatattgtta aaaagaggcg
      421 caacttttta aaattaatga gaatcaaaga gaaaaccaat aatattaatg gaggaataaa
      481 aaatgtaagt aagcattatg gtcattcaat cattctcaaa gatataaatt ttgcacttaa
      541 caagggtgaa attgttggtc tagcagggag aaatggagtt ggtaagagta cgttgatgaa
      601 aattcttgtt cagaataatc aaccgacttc aggtaatatt ataagcagtg ataatgttgg
      661 gtatttaatc gaagaaccaa aattattttt atctaaaaca ggtttagaga atttaaaata
      721 tttgtcaaat ttatatggtg ttgactacaa tcaagaaaga tttagatgtt tgatccaaga
      781 gttagatttg actcagtcta ttaataaaaa agtaaagacc tattctttgg gtacaaaaca
      841 aaaattagct ttgcttctaa ctctcgttac ggaacctgat atattgattt tagatgaacc
      901 gactaatggt ttagatattg aatcatcaca aatagtttta gcggttctaa aaaaattagc
      961 tttacatgaa aatgtgggaa ttttaatatc gagtcataaa ttagaagaca ttgaagaaat
     1021 ttgtgagaga gttcttttct tggagaacgg gcttttgaca tttcaaaaag taggaaaaga
     1081 tagtcataat ttcttgtttg agatagcttt ttcatcagct acagatagag acattttcat
     1141 taccaaacaa gaattttggg atattgttta ggaagaggga ttgagaatta ctatgtctgg
     1201 gaatattcaa aatagtgagc tttttaaatt ttttaacgaa aactctatta aagtagttga
     1261 ttttgaaact aaaaaagaga cgcttaaaga tatttaccta aatcgttcaa aataaaggaa
     1321 ggttataatc atgaaattaa ataaacagaa gaatcggatg atttacgtct tgtctaattt
     1381 tctatatgct atctcagttt ccattattta tgctttgaat ggcattgtgt tactagtcat
     1441 agtaagtaaa ttgggtattc caggtgattt aggattaaat tttatagtag ctattgtagt
     1501 caatacaatt ttgttagtcc tgttttattt tctattatct tacattttct atttatacaa
     1561 attgaaaagt ggcttggtat ttggtatttt agtagcttta ctactcttta tctctaatat
     1621 attaaatacg atgatgatga atactagtaa tgatttgttt atcaaagcaa ttgaacttct
     1681 tcctttttta ttctttacct gtatttgtgg cttcaaatac gatgtctatt agtcagtatc
     1741 ttgtgctaat cactacaatc attttattgt actttttcac tctcaagaaa agcaagaagt
     1801 attcatttta gtttcattta gtattatttt gcatacctaa aatacagtaa aaaatcagtc
     1861 atcttggtat gctcctgctt tcactattca acacgttttt gacttatact aggctcattt
     1921 ccaaaagcat tatataatag tgatatgaaa ccaactaaac taaacaagaa atataagcaa
     1981 taaaaattcg tttaaaagat cttactaaag ctaatactaa ataaaaataa aagagtaaac
     2041 taggaagttt atttcaaaca acctaaaata ctgattttcg gctgaagata atactggagt
     2101 gcaaattaat ggggttataa taaatagctg atagcttgtg ttggttttgg attttttaag
     2161 agtagatgag tattaaaact ataaggagga cgaaggtggc taaaaattta aaattaaaat
     2221 tagctcgggt agagcgtgat ttaacacaag gtcaactggc agaggctgtc ggggtgacac
     2281 gccagactat tggtttaata gaggcgggaa aatacaatcc cagtctctcg ctctgccagt
     2341 ctatttgcag atgtttaggg aaaaccctag accaactatt ttgggaggaa gaagatgaaa
     2401 aatagatttt attattctca attactagac gaaagagaag aacaactgtt caataaagcg
     2461 ggctctgaaa gtttctatat ctgcattgct ttgtcgctcc tatcttatat catttcagta
     2521 ttagcaccaa gcctttttaa ttctaatatg ctgctaatcg ttatcatcat agggacattt
     2581 tactttttca atcgtgcccg ttatctggga gtgacctact atggtcgttt tcattttacg
     2641 attttgggtt gttttttcct aaccttggct attacggctc ttttgatgtt gcagaattat
     2701 caattcaaca tagaaattta tcagcacaat cctttgaatt ttaaatacct gtctgcttgg
     2761 gtcattactt atatcattta ccttccgtgg atctttattg gcaatcttgg tcttaagagc
     2821 tatggcgaat gggctcagaa aaaatttgaa caagatatgg atgaattgga gagtggagaa
     2881 tagcttgtta ctcttttctc aatccagcta aaatgtgata taatagtact aatttattgg
     2941 aatacatgaa agttcttgaa aattttcatg ggtttctagc taaggaagta ggaaaagtat
     3001 gtatccagat gatagtttga cattgcacac ggacttgtac cagatcaaca tgatgcaggt
     3061 ttactttgac caagggattc acaataagaa ggcggtcttt gaggtgtatt tccgccaaca
     3121 gccttttaag aacggctatg cggtttttgc aggtttagaa agaattgtga actatcttga
     3181 agacttgcgt ttttcagata gtgatatagc ctatttggag tcgcttggtt atcatggggc
     3241 gttcttggat taccttcgca atttcaagtt ggagttgacc gttcgttctg cccaagaagg
     3301 ggatttggtt tttgctaatg aaccgattgt gcaggtggaa ggacctctag cccaatgtca
     3361 gttggtcgaa acggctcttt tgaacatcgt caactaccag actttggtgg cgacgaaggc
     3421 agctcgtatt cgttcggtta tcgaagatga acccttgatg gagtttggga cacgtcgggc
     3481 tcaagaaatg gatgcggcca tctggggaac acgcgcagct gtgattggtg gcgccaatgg
     3541 aaccagcaac gtgcgtgcgg gtaagctctt tgacattcct gttttgggaa cccatgccca
     3601 tgccttggta caggtttatg gcaatgacta tgaagctttc aaggcttacg ctgcgaccca
     3661 caaaaattgt gtctttcttg tggataccta tgacaccctt cgcatcggtg taccagctgc
     3721 cattcaggtg gcgcgtgagc tgggtgatca gattaacttt atgggtgtgc ggattgactc
     3781 tggggatatt gcctacattt ctaagaaagt ccgtcagcaa ctggatgagg ctggatttac
     3841 agaggctaag atttatgctt ctaatgatct agatgaaaat accatcctta acctcaagat
     3901 gcaaaaggcc aagattgatg tctggggtgt gggtaccaag ctgattacag cctatgacca
     3961 gccggctctt ggggcggttt acaagattgt tgcaatcgaa gatgaaactg gtcagatgcg
     4021 caatacgatt aagctgtcta ataatgctga aaaagtttct acgccaggta agaagcaggt
     4081 gtggcgcatt accagtcgtg aaaaaggcaa gtcagaaggc gactatatca cttatgatgg
     4141 tgtggatatt agcgacatga cagaaatcaa gatgttccat ccgacctata catacatcaa
     4201 gaagacggtt cgtaattttg atgccgttcc tctcttggtg gatatcttca aagaaggaat
     4261 attagtttac aacttgccta gtttgactga cattcaggat tatgcccgta aggaatttga
     4321 caagttgtgg gatgagtata agcgtgtgct caatccgcag cactatccag tggatttggc
     4381 gcgtgatgta tggcaagata agatggactt gattgataag atgcgcaagg aagcccttgg
     4441 tgaaggagaa gaagaatgag tttgcaagaa acgattatcc aagagctggg tgtcaaacca
     4501 gtgattgatg cccaggaaga aatccgtcgt tctattgatt tcttaaaaag atatctgaaa
     4561 aaacatccct tcctaaaaac ctttgtacta gggatttctg ggggacaaga ctcaaccttg
     4621 gcaggacgtt tggcgcaatt agctatggaa gaactgcgag ctgaaacggg agacgatagc
     4681 tacaaattta tcgctgtccg cctgccatac ggagtgcaag ctgatgaagc agatgctcaa
     4741 aaagccctag ccttcatcca gccagatgtc agcttggttg tgaatatcaa ggaatcagct
     4801 gatgccatga cagctgcagt tgaagcgaca ggtagtcctg tttcagactt caacaagggg
     4861 aatatcaagg cacgttgccg tatgattgct cagtatgccc ttgctggttc ccatagcgga
     4921 gcggtcattg gaacagacca cgccgcggaa aatatcacag gtttctttac caagtttggt
     4981 gacggcggtg cggatattct ccctctttac cgcctcaata aacgccaagg aaaacagctc
     5041 ttgcagaaac ttggcgcaga gccagccctt tatgaaaaaa tcccaacggc agacctagaa
     5101 gaagataaac caggcctagc tgacgaagtc gcacttggag tcacctacgc agagattgac
     5161 gactacctag aaggcaaaac aatcagccca gaagctcaag cgaccattga aaactggtgg
     5221 cacaaaggcc aacacaaacg ccacttaccc atcaccgtat ttgatgactt ttgggagtaa
     5281 aaaggtccgg gggacctttt tagcttcttg ccctgaaatt aaaaagcaag aaaaacctcc
     5341 actggaggtt ttcagcctct catcttgaaa taagaaagtg agagaaggtc tgggggatct
     5401 tgaaccccga gtttagaaat aagaaaatga ggcagattca gtaactcgaa gagttcgatt
     5461 tcatcgtctt acccctgcaa cgatgactag gtttgaaaaa gcttgctaga gcgcatttca
     5521 aaccaggcag caactgcgtc aagaaattag aagacaaact cgttttctag ctgttactga
     5581 gttgagcctt tttactacga gtatagaaat aaggaagtga ggtagcatca tgaaatctat
     5641 cggtacgcaa atattacaga cagaacgttt gattttaaga agatttgtgg agagtgatgc
     5701 agaagccatg tttcaaaatt gggcttcatc cgctgagaat ctgacctatg ttacctggga
     5761 tccccatcct gatgtcgaaa tcactcgaaa ctcgatttgc aattgggttg cttcctatac
     5821 taatctcaac tattataaat gggccatttg tctaaaagaa aacccagagc aagtaatagg
     5881 agatatcagc attgttaaga tagacgaggc tgatttaagc tgtgaaattg gctatgtgtt
     5941 aggcaaggct tactggggaa atggtatgat gacagagact ttgaaagcta tcttggactt
     6001 ttgttttact caagcaggtt ttcaaaaggt cagagcacgt tatgccagtc tcaacccagc
     6061 ttcaggtcgt gtcatggaaa aggctggaat gtcctatcta caaaccattg ttaatggtgt
     6121 agagagaaaa ggctatcttg cggatcttat ttattatggt ataagtaggg aagaatgttg
     6181 aattctattt tctgtttcta tcgaagtcaa ctatttattg taaatataat aattagcatt
     6241 ccaagtttat ttgaaacttt aaaatagcat attgattagt acaagacaga tgttctagtt
     6301 ccttctttaa tctggtttag tgttagttaa aaaatcgctt taagcttgta actaagaggg
     6361 agctaatcga ctagattctc cagccgaaca ggtggtaatg tactttttat agtgtaatcc
     6421 tagctgttgt taaatttaaa atagaatcct ctatcgagtt agggaattaa attcaaccaa
     6481 ttttattcat gttttttcta tcaaattatc taatattaaa atagtctcat tctgatgaga
     6541 aaactat
//
LOCUS       DAVFER010000071         6465 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1105170250
            SAMEA2167659-rid19724873.denovo.071, whole genome shotgun sequence.
ACCESSION   DAVFER010000071 DAVFER010000000
VERSION     DAVFER010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2167659
            Sequence Read Archive: ERR388902
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6465)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6465)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928716.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928716.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 04:07:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,118
            CDSs (total)                      :: 2,073
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 120
            CDSs (without protein)            :: 120
            Pseudo Genes (ambiguous residues) :: 0 of 120
            Pseudo Genes (frameshifted)       :: 67 of 120
            Pseudo Genes (incomplete)         :: 47 of 120
            Pseudo Genes (internal stop)      :: 34 of 120
            Pseudo Genes (multiple problems)  :: 23 of 120
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6465
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2167659-rid19724873.denovo.071"
                     /strain="1105170250"
                     /db_xref="taxon:1313"
     gene            93..1055
                     /locus_tag="VU534_001992"
     CDS             93..1055
                     /locus_tag="VU534_001992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HEU1514521.1"
                     /translation="MNMSNITIDGQEMDLSQTMPSYAQVVSLYDDTSISVSNNETDKV
                     LAGSLYTDTNEQGLTIPSSLLKNWNEQTGKNLTANDLIGKSVSASIVESAAETSKIAQ
                     FQTKIVRVINDEDDMEDSNSFMLSHQMETILKEAGFTKAVSYFILELKDPSQTKVVTE
                     ELQKNKKYTVLSQQRVLDIVITFIRVIQGLLIVLSSQAIVVAAVMIGIIIYINIMQRS
                     KEIGVMKAVGYQNRDVKGIFIYEAIWIVGIALLLAFLVAQGVGSLANAIVSHFYPSIT
                     KVFELNLLSVLGTLVFALLLGYVSAYFPARKISKMDPIESLCYE"
     gene            1232..2239
                     /gene="gap"
                     /locus_tag="VU534_001993"
     CDS             1232..2239
                     /gene="gap"
                     /locus_tag="VU534_001993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HEU1514522.1"
                     /translation="MVVKVGINGFGRIGRLAFRRIQNVEGVEVTRINDLTDPVMLAHL
                     LKYDTTQGRFDGTVEVKEGGFEVNGKFIKVSAERDPEQIDWATDGVEIVLEATGFFAK
                     KEAAEKHLKGGAKKVVITAPGGNDVKTVVFNTNHDVLDGTETVISGASCTTNCLAPMA
                     KALQDNFGVVEGLMTTIHAYTGDQMILDGPHRGGDLRRARAGAANIVPNSTGAAKAIG
                     LVIPELNGKLDGSAQRVPTPTGSVTELVAVLEKNVTVDEVNAAMKAASNESYGYTEDP
                     IVSSDIVGMSYGSLFDATQTKVLDVDGKQLVKVVSWYDNEMSYTAQLVRTLEYFAKIA
                     K"
     gene            complement(2307..3143)
                     /locus_tag="VU534_001994"
     CDS             complement(2307..3143)
                     /locus_tag="VU534_001994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000216776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEU1514523.1"
                     /translation="MTVKQLLEEQLLIPRKIRHFLRIKKHILINQEEVHWKEIVNPGD
                     VCQLTFDEEDYSQKTIPWGNPDLVQEVYQDQHLIIVNKPEGMKTHGNQPNEIALLNHV
                     STYVGQTCYVVHRLDMETSGLVLFAKNPFILPILNRLLEKKEISREYWALVDGNINRK
                     ELVFRDKIGRDRHDRRKRIVDAKNGQYAETHVSRLKQFSNKTSLAHCKLKTGRTHQIR
                     VHLSHHNLPILGDPLYNSKSKTSRLMLHAFRLSFTHPLTLEKLTFTTLSNTFEKELKK
                     NG"
     gene            3269..5464
                     /locus_tag="VU534_001995"
     CDS             3269..5464
                     /locus_tag="VU534_001995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEU1514524.1"
                     /translation="MKLDKLFEKFLSLFKKETSELEDSDSTILRRSRSDRKKLAQVGP
                     IRKFWRRYHLTKIILILGLSAGLLVGIYLFAVAKSTNVNDLQNALKTRTLIFDREEKE
                     AGALSGQKGTYVELTDISKNLQNAVIATEDRSFYKNDGINYGRFFLAIVTAGRSGGGS
                     TITQQLAKNAYLSQDQTVERKAKEFFLALELSKKYSKEQILTMYLNNAYFGNGVWGVE
                     DASKKYFGVSASEVSLDQAATLAGMLKGPELYNPLNSVEDSTNRRDTVLQNMVAAGYI
                     DKNQETKAAEVDMTSQLHDKYEGKISDYRYPSYFDAVVNEAVSKYNLTEEEIVNNGYR
                     IYTELDQNYQANMQIVYENTSLFPRAEDGTFAQSGSVALEPKTGGVRGVVGQVADNDK
                     TGFRNFNYATQSKRSPGSTIKPLVVYTPAVEASWALNKQLDNHTMQYDSYKVDNYAGI
                     KTSREVPMYQALAESLNLPAVATVNDLGVDKAFEAGEKFGLNMEKVDRVLGVALGSGV
                     ETNPLQMAQAYAAFANEGLMPEAHFISRIENASGQVIASHKNSQKRVIDKSVADKMTS
                     MMLGTFTNGTGISSSPADYVMAGKTGTTEAVFNPEYTSDQWVIGYTPDVVISHWLGFP
                     TTDENHYLAGSTSNGAAHVFRNIANTILPYTPGSTFTVENAYKQNGIAPANTKRQVQT
                     NDNSQTDDNLSDIRGRAQSLVDEASRAISDAKIKEKAQTIWDSIVNLFR"
     gene            5517..5669
                     /gene="rpmG"
                     /locus_tag="VU534_001996"
     CDS             5517..5669
                     /gene="rpmG"
                     /locus_tag="VU534_001996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015912025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEU1514525.1"
                     /translation="MALKKASLACAVCGSRNYSIKISGNLKPTRLEVNKFCKHCGKYT
                     THRETR"
     gene            5679..5855
                     /gene="secE"
                     /locus_tag="VU534_001997"
     CDS             5679..5855
                     /gene="secE"
                     /locus_tag="VU534_001997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HEU1514526.1"
                     /translation="MRFIGDIFRLLKDTTWPTRKESWRDFRSIMEYTAFFVVIIYIFD
                     QLIVSGLIRFINIF"
     gene            5910..6446
                     /gene="nusG"
                     /locus_tag="VU534_001998"
     CDS             5910..6446
                     /gene="nusG"
                     /locus_tag="VU534_001998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000376740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HEU1514527.1"
                     /translation="MDSFDKGWFVLQTYSGYENKVKENLLQRAQTYNMLDNILRVEIP
                     TQTVQVEKNGKRKEVEENRFPGYVLVEMVMTDEAWFVVRNTPNVTGFVGSHGNRSKPT
                     PLLEQEIRDILVSMGQTVQEFDFDVEIGQTVRIIDGAFADYTGKITEIDNNKVKMIIS
                     MFGNDTVAEVNLNQIAEL"
BASE COUNT         2007 a         1130 c         1405 g         1923 t
ORIGIN      
        1 aggctttttt atcctgctct tgtttcaatt gactatatat cacggataca gttgggaaag
       61 aagctattaa atatttggag agtccttttg ggatgaacat gtcaaatatt actatagatg
      121 ggcaagaaat ggatctgagt caaacgatgc cttcttatgc tcaagtagtg agtctttatg
      181 atgatacaag tatctctgtt agtaataatg agacggacaa agtgttggct ggatccctct
      241 atactgatac aaatgaacag ggattaacga ttccaagcag tttactaaaa aattggaatg
      301 aacagacagg aaaaaatttg acagctaatg atcttattgg caaatcagtc tcagccagca
      361 ttgtagaaag tgctgccgaa actagtaaga ttgctcaatt tcaaacgaag attgtacgtg
      421 taatcaatga tgaagatgac atggaggaca gcaacagttt catgctgtct catcaaatgg
      481 aaacgatttt gaaagaggct ggatttacga aagctgtatc ttattttatc ttggaactca
      541 aagatccatc acagacaaaa gtagtaacag aagaattaca gaaaaataag aagtatactg
      601 tgctttctca acagagagtt cttgatattg tgattacctt tattcgtgtt attcagggat
      661 tattgattgt gctttcatca caagctattg tggtagcagc ggttatgatt ggtatcatta
      721 tttacatcaa tatcatgcaa cgttccaagg aaataggtgt catgaaagca gttggttatc
      781 agaatcgtga tgtcaaagga atttttattt acgaggctat ctggattgta ggcatcgcct
      841 tgctgctggc atttttggtt gcacaagggg tgggaagttt ggcgaatgcg attgtaagtc
      901 acttttaccc atccatcact aaggtttttg aattaaatct tttatctgtt ttaggaactc
      961 tagttttcgc tctattactt ggttatgtct cagcctactt cccggcgcgt aagattagta
     1021 aaatggatcc tatagaatcg ttatgctatg aatagtaagg gattccttgg tttacagtct
     1081 taaaaagaaa ctaacataga aaaacaatgg ccatacttgc aattcaactc aaatagttgt
     1141 ataataggtt tgttgaaagg tgatttgtag tgattcaagt tactcttttc acaataaaaa
     1201 tttcatgatt ttcataagga ggaaatcact aatggtagtt aaagttggta ttaacggttt
     1261 cggacgtatc ggtcgtcttg ctttccgtcg tatccaaaac gtagaaggtg ttgaagttac
     1321 acgcatcaac gaccttacag atccagttat gcttgcacac ttgttgaaat acgacacaac
     1381 tcaaggtcgt ttcgacggta ctgttgaagt taaagaaggt ggatttgaag ttaacggtaa
     1441 attcatcaaa gtttctgctg aacgtgatcc agaacaaatc gactgggcta ctgacggtgt
     1501 agaaatcgtt cttgaagcta ctggtttctt tgctaagaaa gaagcagctg aaaaacacct
     1561 taaaggtgga gctaaaaaag ttgttatcac tgctcctggt ggaaacgacg ttaaaacagt
     1621 tgtattcaac actaaccacg acgttcttga cggtactgaa acagttatct caggtgcttc
     1681 atgtactaca aactgcttgg ctccaatggc taaagctctt caagacaact ttggtgttgt
     1741 tgaaggattg atgactacta tccacgctta cactggtgac caaatgatcc ttgacggacc
     1801 acaccgtggt ggtgaccttc gccgtgctcg cgctggtgct gcaaacatcg ttcctaactc
     1861 aactggtgct gcaaaagcta tcggtcttgt aatcccagaa ttgaatggta aacttgacgg
     1921 atctgcacaa cgcgttccaa ctccaactgg atcagttact gaattggtag cagttcttga
     1981 aaagaacgtt actgttgatg aagtgaacgc agctatgaaa gcagcttcaa acgaatcata
     2041 cggttacaca gaagatccaa tcgtatcttc agatatcgta ggtatgtctt acggttcatt
     2101 gtttgacgca actcaaacta aagttcttga cgttgacggt aaacaattgg ttaaagttgt
     2161 atcatggtac gacaacgaaa tgtcatacac tgcacaactt gttcgtactc ttgaatactt
     2221 cgcaaaaatt gctaaataat tcttgagttg atagaaagca aggctttgtg gtcttgcttt
     2281 tttatatgga aaaatggatg acacgatcat ccattctttt ttaattcttt ttcaaatgta
     2341 tttgaaaggg tagtgaaagt tagcttctct aaagtaagtg ggtgggtaaa ggaaagtcgg
     2401 aaggcatgaa gcataagccg gcttgtcttt gatttactat tatagagagg gtctcccagg
     2461 ataggaagat tatgatgcga aaggtgcaca cgaatctgat gggttcgccc tgtctttagc
     2521 ttgcaatgag ccaaggaagt cttgtttgag aattgcttta atctgcttac atgcgtttca
     2581 gcatattgcc cattttttgc atcaactatt ctttttctac gatcatggcg atcacgtcca
     2641 attttgtctc tgaaaacaag ttcttttctg ttgatatttc catcaactag agcccaatat
     2701 tctctagaaa tctctttttt ctccaataag cgattgagaa tgggcaggat aaaaggattt
     2761 ttggcaaaga gaactaagcc actggtttcc atgtccagac gatgaacgac atagcaggtt
     2821 tggccaacat aggtactgac atggttaaga agggcaattt cgtttggttg attaccatgc
     2881 gttttcatcc cctctggttt gtttacaata atcaagtgtt gatcttgata aacttcctgc
     2941 actaagtctg ggttgcccca agggatcgtc ttttgggaat aatcttcctc gtcaaaagtc
     3001 aactggcaaa catctccagg atttacgatt tccttccagt ggacttcttc ttgatttatc
     3061 aaaatatgtt tcttgattct caaaaaatga cggatttttc tagggatgag gagttgttcc
     3121 tcaagtaatt gctttactgt catttgaggt agagaggcgg gtaatgtaaa tgtgaattgc
     3181 atacagatat tgtaacaaaa aaagccctat ttggatagga aatagctaaa ttcttgtctt
     3241 cctatgatga agatgataaa ataaacgcat gaaattagat aaattatttg agaaatttct
     3301 ttctcttttt aaaaaagaaa caagtgaact agaggactct gattctacta tcttacgtcg
     3361 ctctcgtagt gatcgaaaaa aattagccca agtaggtccg attcgaaaat tctggcgtcg
     3421 ttatcatcta acaaagatta tccttatact aggtttgagt gcaggcttgc tagttggaat
     3481 ctatttgttt gctgtagcca agtcgaccaa tgtcaatgat ttgcaaaatg ccttgaaaac
     3541 tcggactctt atttttgacc gtgaagaaaa agaggctggt gccttgtctg gtcaaaaggg
     3601 aacctatgtt gagctgactg acatcagtaa aaacttgcag aatgctgtta ttgcgacaga
     3661 agaccgttct ttctataaaa atgacgggat taactatggc cgttttttct tggctattgt
     3721 cactgctgga cgttcaggtg gtggctctac cattacccaa cagctggcta aaaacgccta
     3781 tttatcgcag gatcaaactg ttgagagaaa agcgaaagaa tttttccttg ccttagaatt
     3841 aagcaaaaaa tatagtaagg agcaaattct aaccatgtac cttaacaacg cttattttgg
     3901 aaatggtgtg tggggtgtag aagatgcgag taagaaatac tttggagttt ctgcatcaga
     3961 agtgagtctg gatcaagctg cgactctggc agggatgctc aaggggccgg aactgtataa
     4021 tcccttgaat tccgtagaag attctactaa tcggcgcgat actgtcttgc agaatatggt
     4081 tgcagcagga tatattgata aaaaccaaga aaccaaagct gctgaagttg atatgacttc
     4141 gcaattgcac gataagtatg aaggaaaaat ctcagattac cgttacccct cttattttga
     4201 tgcggtggtt aatgaagctg tttccaagta taatctaaca gaggaagaga ttgtcaataa
     4261 tggctaccgc atttacacag agctggacca aaactaccaa gcaaatatgc agattgttta
     4321 tgaaaacaca tcgctatttc cgagggcaga ggatggaacg tttgctcaat caggaagtgt
     4381 agccctcgaa ccgaaaacag ggggagttcg tggagttgtc ggtcaagttg ctgacaatga
     4441 taaaactgga ttccggaatt tcaactatgc aacccaatca aagcgtagtc ctggttctac
     4501 aattaagcct ttagttgttt atacgccagc agttgaagca agctgggctt tgaataagca
     4561 gttggataac cataccatgc agtatgacag ctataaggtt gataactatg cagggatcaa
     4621 aacgagtcga gaagttccta tgtatcaagc cttggcagaa tcgcttaatc tacctgctgt
     4681 tgccactgtt aatgatttgg gtgtcgacaa ggcttttgag gcaggcgaaa aattcggact
     4741 caacatggaa aaggtcgacc gtgttcttgg tgtcgccttg ggaagcggtg ttgaaaccaa
     4801 ccctcttcaa atggctcaag catacgccgc ctttgcaaat gaaggtttaa tgcctgaagc
     4861 tcattttatt agtagaattg aaaatgctag tggacaagtt attgcgagtc ataaaaattc
     4921 acaaaaacgg gtgattgata agtctgtagc tgacaagatg accagtatga tgttggggac
     4981 tttcaccaac ggtaccggta ttagttcatc gcctgcagac tatgtcatgg cagggaaaac
     5041 tggaacaact gaagcagttt tcaatccgga gtacacaagt gaccagtggg taattggtta
     5101 tactccggat gtagtgatta gccactggct tggctttccg accactgatg aaaaccacta
     5161 tctagctggc tctacttcaa acggtgcagc tcatgtcttt agaaacattg ccaataccat
     5221 tttaccttat acgccaggaa gtacctttac ggttgaaaat gcttataagc aaaatggaat
     5281 tgcaccagcc aatacaaaaa gacaagtaca aaccaatgat aatagccaga cagatgataa
     5341 tttgtctgat attcgagggc gtgcgcaaag tctagtagat gaggctagcc gggctatctc
     5401 agatgcgaag attaaggaaa aggctcaaac aatatgggat tcgatagtca atctatttcg
     5461 ctaagatgct tgtcaaagcc tagctttctt gttataatgg ataagatgga ggcgttatgg
     5521 cactaaaaaa agcaagccta gcttgtgcgg tttgtggttc gagaaactat tcaatcaaga
     5581 tcagcggaaa cctcaagcct acacgactag aagtaaataa attttgtaag cattgtggca
     5641 agtacactac acacagagaa acgagatagg agagagcgat gcgttttatt ggagatattt
     5701 ttagacttct taaagacaca acatggccaa ctcgcaagga aagctggaga gattttcgtt
     5761 ctatcatgga atacacagct ttctttgtag taattattta catttttgac cagttgattg
     5821 tttcaggttt gattcgattt attaacattt tttagaagat tagtggagtt aattacacta
     5881 gaaatcttct atttatgaaa ggaaatatca tggatagttt tgataaaggg tggtttgttt
     5941 tacaaactta ttctggttat gaaaataagg tgaaagaaaa tctattacaa cgtgcacaaa
     6001 cctacaatat gttggataat attctacgcg ttgaaattcc aacacaaaca gtgcaagttg
     6061 aaaaaaatgg aaagagaaaa gaagtagaag aaaatcgctt tccaggttat gttcttgtag
     6121 aaatggtcat gacagatgaa gcttggtttg ttgttcgaaa cacaccaaat gttacaggat
     6181 ttgtcggatc acacgggaac agatcaaaac caactccatt attggaacaa gaaattcgcg
     6241 acattttggt atctatggga caaactgttc aagaatttga tttcgatgtt gagattggtc
     6301 aaactgtacg tattattgat ggtgcttttg cagactacac tggtaagatt acagaaattg
     6361 ataataacaa agtgaaaatg attatctcta tgtttggtaa tgacacagtt gcagaagtaa
     6421 atctaaacca aatcgcagaa ttataaccct gagagaggct ggagc
//
LOCUS       DAVFER010000072         5842 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1105170250
            SAMEA2167659-rid19724873.denovo.072, whole genome shotgun sequence.
ACCESSION   DAVFER010000072 DAVFER010000000
VERSION     DAVFER010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2167659
            Sequence Read Archive: ERR388902
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5842)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5842)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928716.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928716.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 04:07:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,118
            CDSs (total)                      :: 2,073
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 120
            CDSs (without protein)            :: 120
            Pseudo Genes (ambiguous residues) :: 0 of 120
            Pseudo Genes (frameshifted)       :: 67 of 120
            Pseudo Genes (incomplete)         :: 47 of 120
            Pseudo Genes (internal stop)      :: 34 of 120
            Pseudo Genes (multiple problems)  :: 23 of 120
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5842
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2167659-rid19724873.denovo.072"
                     /strain="1105170250"
                     /db_xref="taxon:1313"
     gene            complement(120..1130)
                     /gene="ccpA"
                     /locus_tag="VU534_001999"
     CDS             complement(120..1130)
                     /gene="ccpA"
                     /locus_tag="VU534_001999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000990602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="HEU1514528.1"
                     /translation="MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEV
                     IDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFSSLAKGIDDIAEMYKYNIVLANS
                     DEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
                     VNIDYKQATIDAVSYLAKENERIAFVSGPLVDDINGKVRLVGYKETLKKAGITYSEGL
                     VFESKYSYDDGYALAERLISSNATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSD
                     DSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREVLLPHGLTERSSTRK
                     RK"
     gene            complement(1555..2154)
                     /locus_tag="VU534_002000"
     CDS             complement(1555..2154)
                     /locus_tag="VU534_002000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU1514529.1"
                     /translation="MKVLVAEDQSMLRDAMCQLLMLQPDVESVFQAKNGQEAIQLLEK
                     ESVDIAILDVEMPVKTGLEVLEWIRAEKLETKVVVVTTFKRPGYFERAVKAGVDAYVL
                     KERNIADLMQTLHTVLEGRKEYSPELMEVVMMHPNPLTEQEIAVLKGIAQGFSNQEIA
                     DKLYLSNGTVRNYVTNILSKLDAGNRTEAANIAKESGWL"
     gene            complement(2155..3252)
                     /locus_tag="VU534_002001"
     CDS             complement(2155..3252)
                     /locus_tag="VU534_002001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001848091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEU1514530.1"
                     /translation="MLERLKRIHYMFWISLIFMIFPILSVVTGWLSAWHLLIDILFVV
                     AYLGVLTTKSQRLSWLYWGLMLTYVVGNTAFVAVNYIWFFFFLSNLLSYHFSVRSLKS
                     LHVWTFLLAQVLVVGQLLIFQRIEVEFLFYLLVILTFVDLMTFGLVRIRIVEDLKEAQ
                     VKQNAQINLLLAENERSRIGQDLHDSLGHTFAMLSVKTDLALQLFQMEAYPQVEKELK
                     EIHQISKDSMNEVRTIVENLKSRTLTSELETVKKMLEIAGIEVQVENHLDKSSLTQEL
                     ESTASMILLELVTNIIKHAKASKVYLKLERTEKELILTVRDDGCGFASISGDELHTVR
                     NRVFPFSGEVSVISQKHPTEVQVRLLYKERK"
     gene            complement(3252..3989)
                     /locus_tag="VU534_002002"
     CDS             complement(3252..3989)
                     /locus_tag="VU534_002002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004249339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU1514531.1"
                     /translation="MKRWLALSKIEFLLTKRQLIYYLLSVGMPTAFYLFFSGIYQDTP
                     GELANFMRDYLISMTAFSMMSTAIFSFPVVLHTDKINNWQKTLRHSPVNMVEYYLSKI
                     TSMLVDYLVSILVVFSVGHFVRGVDMSLGNWIGAALLLIVGSIAFVALGLTLTLLPTS
                     QLMSVVGNLLYLGLAVLGGLWMPISLFPDWMQVVGKCLPTYQLMELLKTFLNEGGINL
                     SATVYLLVFSVVLFGLTIYLQGHKENA"
     gene            complement(3991..4876)
                     /locus_tag="VU534_002003"
                     /pseudo
     CDS             complement(3991..4876)
                     /locus_tag="VU534_002003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219360.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            complement(4863..5057)
                     /locus_tag="VU534_002004"
     CDS             complement(4863..5057)
                     /locus_tag="VU534_002004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000820189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1514532.1"
                     /translation="MKRGIIYFFIGLSLLVWLVEMFTGWFDQTLLRQFIRGALGFGFM
                     IFVVFLMRMEWLKGEYHEYD"
     gene            complement(5054..5185)
                     /locus_tag="VU534_002005"
     CDS             complement(5054..5185)
                     /locus_tag="VU534_002005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000490981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine aminotransferase"
                     /protein_id="HEU1514533.1"
                     /translation="MFSGLDESFYHFPWELFAGFGMMSWLVREGLKLVGDVKKELEE"
BASE COUNT         1871 a         1309 c          947 g         1715 t
ORIGIN      
        1 aaacagtgtg ttgcgcagcc tttaatcagc cgcctagtcc gctctatggt attcattaag
       61 tcaacatctc ttgtttaaga gcaccaaatc aggaaatctt ctcgattccc tgattttttc
      121 tatttacgtt ttcgtgttga gctacgttct gtcaaaccat gaggtaagag aacttcacgt
      181 tcttccaact cttccttatg cataatcttg gtcaacatac gcatactaat ggcaccaagg
      241 tcataaagag gttgggcaat cgttgtcaag tttggacggg taaagcgtga gatttgtgaa
      301 tcatcactag taataatttc aaaatcttct ggcacagaaa cacccttatc agccaaaccg
      361 ttcaagactc ctgctgccaa ctcatcacct gtcacaactg ctgcagttgc atttgatgaa
      421 atcaaacgct ctgctaaggc gtaaccatca tcatagctat atttagattc aaataccaaa
      481 ccctcactat aagtgattcc tgcttttttc aaggtttcct tgtagccaac taaacgaacc
      541 ttaccattga tgtcatccac tagcggaccg ctaacgaaag caatacgctc attttcttta
      601 gcaaggtaac tcactgcatc aattgttgct tgcttatagt caatattgac acttggcaac
      661 tggtgctcaa catcgacagt tcctgcgaga acaatcggag tacgtgaacg cgaaaattct
      721 gagcgaattt tatctgtcaa gtgatacccc atatagataa tgccatctac ctgctttgaa
      781 aagagggtat tgacaacaga aacttctttc tcgttatctt catcgctatt agctaggaca
      841 atattgtact tgtacatttc tgcaatatca tcaatcccct tagccaaact cgaaaaataa
      901 ccattggtaa tatttggaat cacgacaccg acagtggttg tctttttact tgcaagacca
      961 cgcgcaactg catttggacg ataatccaaa cgatcaatta cctctagcac ttttttacgg
     1021 gtattctctt ttacattttt attgccattg accacacggc tgaccgtcgc catggaaaca
     1081 cctgcttcac gagcgacatc ataaatggtt actgtatcat ctgcattcat tccttttcct
     1141 gtcctttcta tctcacacat tcttttacaa gtagaggtac tgattgaagc tctatatcta
     1201 cttacaaaag tgaagatgtg aaaatttcgt tttcatattt ctacttattc cattctatca
     1261 ctaattgtaa acactttcaa gtgttttttg aagattgatt gaaaaaattt catagaaaac
     1321 ctaggtttag ctccttgcta ccaccttaga ctaaacaaaa aggaggaaac taagccctcc
     1381 taaagttata gtaaaatgaa ataagaacag gataaatcga tcaggacagt caaatcgatt
     1441 tctaacaatg ttttagaagt agaggtgtac tattctagtt tcaatctact ataggtattg
     1501 ttccattcac taccgtcaat tttagcacat agtcttcatg aaaatattat atcatcataa
     1561 ccaaccagat tctttcgcga tattagctgc ctctgttcga ttacctgcat ctagtttcga
     1621 aagaatattg gtgacatagt ttcggactgt tccgttggat agataaagtt tgtctgcaat
     1681 ttcttggtta gagaagccct gagcaattcc ctttaaaact gcgatttctt gctccgttaa
     1741 tggattggga tgcatcatca ccacttccat caattcaggc gaatactcct tgcgtccttc
     1801 gaggacggtg tgcaaggttt gcatgaggtc tgcaatgttt ctttctttta atacataagc
     1861 atctactcca gccttgaccg cacgttcaaa atacccagga cgcttgaagg tcgtcaccac
     1921 aaccaccttt gtttcaagct tttctgctcg tatccactcc aagacttcaa gacctgtctt
     1981 aacaggcatt tctacgtcaa ggatggcgat atctacagac tccttttcta atagttggat
     2041 tgcttcttgc ccattcttgg cttgaaagac agactctaca tccggttgaa gcatgagcaa
     2101 ctggcacatg gcatctcgca acatactttg atcttctgcg actaatactt tcatctactt
     2161 tctctcctta taaagtagtc gaacctgcac ttcagttgga tgtttctgac tgattacact
     2221 tacttctcct gaaaatggaa aaacacgatt tcggactgta tggagctcat ccccgcttat
     2281 agaggcaaag ccacagccat catctctcac tgttagaatg agttctttct ctgtccgttc
     2341 taatttcaag tagactttag acgctttagc atgtttgatg atattggtca ctaattcaag
     2401 caaaatcatg gaagccgttg actccaattc ctgagttaag ctagacttgt ccaagtgatt
     2461 ctcaacttga acctcaattc cagcaatttc taacatcttt ttcacagtct ctagttcgga
     2521 tgtcaaagtt ctagacttaa gattttccac aatggttcgc acttcattca tggaatcctt
     2581 gctgatctgg tgaatttctt ttaattcctt ttccacctgt ggataagcct ccatctgaaa
     2641 taactgcaag gctaaatctg tcttgacact cagcatagca aaggtatgtc ccagactatc
     2701 atgcaaatcc tgaccgatac gactacgttc attttcagca agcaatagat ttatctgagc
     2761 attttgcttg acctgagctt ctttcaaatc ctcgacaata cgaatccgaa ccaatccaaa
     2821 agtcattaaa tcgacaaaag taagaattac aagtagatag aatagaaact caacttcgat
     2881 tctctgaaaa atcaacagtt gccccacaac aaggacttga gcaagaagaa aagtccagac
     2941 atgtaaagac tttaaactac gtacgctgaa atgataactt aagagattgg ataggaaaaa
     3001 gaaaaaccag atataattaa cagcaacaaa ggcagtattc ccaactacat aagtcagcat
     3061 gaggccccaa tatagccaag ataggcgctg gctcttagtt gttaaaacac ccaaatatgc
     3121 cactacaaat agaatatcaa tcaataaatg ccaggcagaa agccacccag tcactacaga
     3181 caggatgggg aaaatcataa aaattaaact gatccaaaac atataatgta ttcttttcag
     3241 tctttcaagc attaagcatt ctccttatga ccttgaaggt aaatggtcaa accaaacaaa
     3301 actactgaaa aaacaagtaa ataaactgtg gctgatagat tgatgccacc ctcatttaag
     3361 aaggtcttga gcaactccat caactgatag gtcgggagac acttacctac tacttgcatc
     3421 cagtctggaa ataaagagat aggcatccag agtccaccta aaacagccaa ccctagataa
     3481 agaagattgc ccacgacaga catcaactga ctagttggta agagagtcaa ggtcaaacca
     3541 agcgctacga aggcaatact tcctactatc agcaaaagtg cagccccaat ccaatttcca
     3601 agagacatgt ccacacctct tacaaaatgc ccaactgaga aaaccaccaa gattgaaacc
     3661 aaataatcaa ccagcatact tgttatcttt gatagataat attctaccat atttacaggg
     3721 ctatgacgca atgttttctg ccagttgttg atcttgtcgg tatgtaaaac aactgggaat
     3781 gagaagatag ctgttgacat catggaaaat gcagtcatgg agataagata atcacgcata
     3841 aaattcgcga gttcacctgg tgtgtcctga tagataccag aaaaaaataa atagaaagcc
     3901 gtcggcatcc ctactgacaa tagataatag atcaattgtc gtttggtcaa taaaaattct
     3961 atcttactaa gtgctagcca tcgtttcatc ttagttatct cccttctgcg tttcttcaaa
     4021 gattgtatcc aacaaactac gattattaac ttcaatttct tgtatgccac atcctgcttg
     4081 aactaacagt tcccaaaaag catctgcttc gcgtgtgact acttgtagag catcctgttt
     4141 ttgtgaccag ttttcaacca agttagactg ctcaatgact tccttgtatg ccagaggaag
     4201 gataaaatgc ttttcaattc cctcactacg catagctagg aggcgtcgta tcacgaatca
     4261 actctccctt atttaaaacc aaaatccggt cagccgtatg ctctacctct tcaatataat
     4321 gagacgaata gagaatcgtg actccttgcg cttttaggtc ccgaacgatt tcccaaaagc
     4381 gttgacgagt tgaagtatcc atggcagcag ttggttcatc taaaaagaca agctttggtc
     4441 gcccaatcaa ggtcaagaca aaagagaaga gacgcttttg cccgcctgac aatttttctg
     4501 cgaattgctc tttttgttgc tggtcaaact gcaatagttg atcgatttcc tgatcgctca
     4561 aggaatttgg atagatacgt tgaaagaaag caatcaactc tttgaccttt aatttctgaa
     4621 cgatgacatt ttcttgaggc agataacctc taatatagtc taactgagaa ctcgtcactg
     4681 acaagccttg gatggatact tgaccgcttg tgaccagttt atctccaagc agacagtcca
     4741 agagtgtggt cttcccagca ccattgggcc caatcaaggc gacgcattca ccttcagcta
     4801 cctcaaagga aatacccttc aaaatagcct tgcccttgat gtttttattt aggctttcta
     4861 ccttaatcat attcatgata ttctcctttc aaccactcca ttctcataag gaaaacgacg
     4921 aaaatcataa atccaaaccc caaagcacca cgaatgaatt ggcgaagcaa ggtttggtca
     4981 aaccaacctg taaacatttc cactaaccat accaagagtg acaggccgat aaagaaatag
     5041 atgatccctc tcttcattcc tcaagctcct ttttcacatc tccgactaat ttcaaacctt
     5101 ctctaacaag ccaagacatc attccaaagc cagcaaagag ctcccaagga aaatgataga
     5161 aactctcatc caatcccgaa aacatgagtt aggtcataac tcctgctact actaaactca
     5221 ctgcgataat cattttattt ctcatctctt cttcctccat ttcatactac aattatagtc
     5281 ttttgaaatc agaggagaca gaagcttctg tcactagaaa atatgacaaa tgtcataaaa
     5341 aattctgttc aaaacaagca agatacacta tacaataaaa cacaattaga aaaatctaag
     5401 gcaacttcct caaaagagat atcaaaccca attcacacca taatgtaaac taatacttat
     5461 ttaaaatcaa aaagagtaga aatttttatc agacaaacac atatatagtg tattgaatct
     5521 ataacagtag gccttaaata ctaaaatatt tctataaatt aatttaactt tcctgataga
     5581 gctgttcata tcttatttca attctctaaa ttatacgttg aacaaaaccc ttctatttct
     5641 ttcttaaaga tttataagag ttataaaatc tgttaaattt caatgtgtat acctaaacta
     5701 cggtatttat tgaaaagact ggagacaaaa agtatacgct gccaaaatga attactgaaa
     5761 atcaaaaaag agagaaccaa actgattccc tcttaatgta tataatatct agttttaaaa
     5821 atacacactc acatatctct gt
//
LOCUS       DAVFER010000073         5715 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1105170250
            SAMEA2167659-rid19724873.denovo.073, whole genome shotgun sequence.
ACCESSION   DAVFER010000073 DAVFER010000000
VERSION     DAVFER010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2167659
            Sequence Read Archive: ERR388902
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5715)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5715)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928716.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928716.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 04:07:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,118
            CDSs (total)                      :: 2,073
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 120
            CDSs (without protein)            :: 120
            Pseudo Genes (ambiguous residues) :: 0 of 120
            Pseudo Genes (frameshifted)       :: 67 of 120
            Pseudo Genes (incomplete)         :: 47 of 120
            Pseudo Genes (internal stop)      :: 34 of 120
            Pseudo Genes (multiple problems)  :: 23 of 120
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5715
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2167659-rid19724873.denovo.073"
                     /strain="1105170250"
                     /db_xref="taxon:1313"
     gene            171..371
                     /locus_tag="VU534_002006"
     CDS             171..371
                     /locus_tag="VU534_002006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000226586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1514534.1"
                     /translation="MVASASASSTSTQAQEQVDKSELRALSQELDQRLKALATVSDPK
                     IDATKAVLLDAQKAPEDSALTE"
     gene            413..817
                     /locus_tag="VU534_002007"
     CDS             413..817
                     /locus_tag="VU534_002007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000377663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1514535.1"
                     /translation="MDSLKDVKANASDSKPAQDKKDAKQGTEDSKDSDKMTETNSVPA
                     GVIVVSLLALLGVIAFWLIRRKKESEIQQLSTELIKVLGQLDAEKADKKVLAKAQNLL
                     QETLDFVKEENGSAETETKLVEELKAILDKLK"
     gene            1048..1755
                     /gene="ccdA2"
                     /locus_tag="VU534_002008"
     CDS             1048..1755
                     /gene="ccdA2"
                     /locus_tag="VU534_002008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004237834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HEU1514536.1"
                     /translation="METIVFLISVFLAGVLSFFSPCIFPLLPVYAGILLDDQESAKSF
                     SLFGRKVLWSGLIRTLCFIAGISLIFFILGFGAGYFGHILYANWFRYGMGAIIIILGL
                     HQMEIFHLKKLEVQKSFTFKKSDSNRYWSAFLLGITFSFGWTPCIGPVLSSVLALAAS
                     GGNGAWQGAIYTLIYTLGMALPFLVLALASGLVMPYFSKIKRHMMLLKKIGGFLIVLM
                     GILLLLGQVNVLAGIFE"
     gene            1766..2323
                     /gene="sdbB"
                     /locus_tag="VU534_002009"
     CDS             1766..2323
                     /gene="sdbB"
                     /locus_tag="VU534_002009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     lipoprotein SdbB"
                     /protein_id="HEU1514537.1"
                     /translation="MKKVMFAGLSLLSLVVLMACGEEETKKTQAAQQLKQQTTVQQIA
                     VGKDAPDFTLQSMDGKEVKLSDFKGKKVYLKFWASWCGPCKKSMPELMELAAKPDRDF
                     EILTVIAPGIQGEKTVEQFPQWFQEQGYKDIPVLYDTKATTFQAYQIRSIPTEYLIDS
                     QGKIGKIQFGAISNADAEAAFKEMN"
     gene            2697..4088
                     /locus_tag="VU534_002010"
     CDS             2697..4088
                     /locus_tag="VU534_002010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001020339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HEU1514538.1"
                     /translation="MNIFRTKNVSLDKTEMHRHLKLWDLILLGIGAMVGTGVFTITGT
                     AAATLAGPALVISIVISALCVGLSALFFAEFASRVPATGGAYSYLYAILGEFPAWLAG
                     WLTMMEFMTAISGVASGWAAYFKGLLSQYGIAFPQALNGTFNPQAGTFVDLLPILVLV
                     LVTSLVLLNAKAALRFNSILVILKFSALALFVLVGIWNIKFDNWSNFAPYGFGQIYGA
                     STGIMAGASLMFFGFLGFESISMAVDEVKTPQKNIPRGIVLSLSIVTILYALVTLVLT
                     GVVHYSHLNVDDAVAFALRSVGISWAANYVSLVAILTLITVCISMTYALSRMIYSLAR
                     DGLVPAAFKELTKTSKIPKNATILTGLASAVAAGMFPLASIAAFLNICTLAYLIMLAY
                     GLIRLRKEKGMPKAGEFKTPLVPLLPILSIIICLSFMLQYNMNTWIAFLVALLVGSII
                     YFTYGYKHSTIEE"
     gene            4231..5148
                     /gene="adcAII"
                     /locus_tag="VU534_002011"
     CDS             4231..5148
                     /gene="adcAII"
                     /locus_tag="VU534_002011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000744528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding lipoprotein AdcAII"
                     /protein_id="HEU1514539.1"
                     /translation="MKKQNLFLVLLSVFLLCLGACGQKESQTGKGMKIVTSFYPIYAM
                     VKEVSGDLNDVRMIQSSSGIHSFEPSANDIAAIYDADVFVYHSHTLESWAGSLDPNLK
                     KSKVKVLEASEGMTLERVPGLEDVEAGDGVDEKTLYDPHTWLDPEKAGEEAQIIADKL
                     SEVDSEHKETYQKNAQAFIKKAQELTKKFQPKFEKATQKTFVTQHTAFSYLAKRFGLN
                     QLGIAGISPEQEPSPRQLTEIQEFVKTYKVKTIFTESNASSKVAETLVKSTGVGLKTL
                     NPLESDPQNDKTYLENLEENMSILAEELK"
     gene            5156..>5715
                     /locus_tag="VU534_002012"
     CDS             5156..>5715
                     /locus_tag="VU534_002012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HEU1514540.1"
                     /translation="MKINKKYLAGSVAVLALSVCSYELGRHQAGQVKKESNRVSYIDG
                     DQAGQKAENLTPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIISE
                     ELLMKDPNYQLKDSDIVNEIKGGYVIKVDGKYYVYLKDAAHADNIRTKEEIKRQKQEH
                     SHNHGGGSNDQAVVAARAQGRYTTDDG"
BASE COUNT         1744 a         1014 c         1229 g         1728 t
ORIGIN      
        1 agtaaaatga aataagaata ggacaaatcg atcaggacag taaaatcgaa ttctaacaat
       61 gttttagaag tccatatgta ctattctagt ttcaatatac cataactgtt cctagtcaac
      121 ctgcaagccc tgtcccagct ccaagctcag ctccgactca agatcctaga gtggtagcaa
      181 gcgcttcggc tagctcaacg agcacacaag ctcaagagca agttgacaag tctgaacttc
      241 gtgccttgag tcaagagtta gaccaacgct tgaaagcttt ggcaacagta tctgatccga
      301 aaatcgatgc aaccaaggct gtcctcctag atgctcaaaa agctccggaa gatagtgcct
      361 tgacagagta aggtctgcat actgcagtag agtctgtgaa ggctgggctg ccttggactc
      421 tctcaaagat gtgaaagcaa atgctagcga cagcaagcct gcacaggaca agaaggatgc
      481 aaaacaagga acggaagata gtaaggattc agataagatg actgaaacaa actcagttcc
      541 ggcaggagtg attgtggtca gtctacttgc cctcctaggc gtgattgcct tctggctgat
      601 tcgccgtaag aaagagtcag aaatccagca attaagcacg gaattgatca aggttctagg
      661 acagctagat gcagaaaaag cggataaaaa agtccttgcc aaagcccaaa accttctcca
      721 agaaaccctt gatttcgtga aagaagaaaa tggctcagca gagacagaaa ctaaactagt
      781 agaggagctt aaagcaatcc ttgacaaact caagtaaaac atgatttatg aaatgtcaga
      841 cctaaaagac attttcgttc acaaaagcag cgatgagtaa tccttgtcgt tgctttttgg
      901 ctattttggg ggataagatc cgccttgact agcaaaagaa aagattggtc caatagtgcc
      961 cgatacgatt ttgcgtagca gaaagcttac aaataaaatt gaatatagta aaataggatt
     1021 agaattatta agaaagttgg ttctttattg gaaacgatag tatttttaat ctctgttttt
     1081 ctagcaggtg ttttatcctt tttttctcct tgtatttttc ctcttctgcc agtctatgct
     1141 gggattttat tggatgatca agaaagtgca aaaagctttt ctttgtttgg gagaaaggtt
     1201 ctctggtcag gcttgattcg aacactttgc tttatcgctg gtatctctct cattttcttt
     1261 attctaggct ttggtgctgg ttactttggt catattctct atgcaaattg gtttcgatat
     1321 ggcatgggag ctattattat cattttgggt cttcaccaga tggaaatttt tcatttgaag
     1381 aaattagaag ttcaaaaaag ttttaccttt aaaaaatcag attctaatcg ttattggtca
     1441 gcttttttac ttggtattac ctttagcttt ggttggacac cttgtattgg tccagtttta
     1501 agttctgttt tagcacttgc ggcttctgga ggcaatggcg cttggcaagg agcgatttat
     1561 actctcattt acactctggg catggccctt cctttcttgg tattggcact agcttcaggt
     1621 ctagtcatgc catattttag taaaatcaag cgtcatatga tgctactaaa gaaaattggt
     1681 ggtttcctca ttgttttaat gggaattttg ttactattag gacaagtaaa tgttctagct
     1741 ggaatttttg aataaaggag gacaaatgaa aaaagtaatg tttgctggct taagtctctt
     1801 gtcattagtt gtattgatgg cctgtggtga ggaagaaact aaaaagactc aagcagcaca
     1861 acagctaaaa caacaaacga ctgtacaaca aattgctgtt ggaaaagatg ctccagactt
     1921 cacattgcaa tccatggatg gcaaagaagt taagttatct gattttaagg gtaaaaaggt
     1981 ttacttgaag ttttgggctt catggtgtgg tccatgcaag aaaagtatgc cagagttgat
     2041 ggaactagcg gcgaaaccag atcgtgattt cgaaattctt actgtcattg caccaggaat
     2101 tcaaggtgaa aaaactgttg agcaattccc acaatggttc caggaacaag gatataagga
     2161 tatcccagtt ctttatgata ccaaagcaac caccttccaa gcttatcaaa ttcgaagcat
     2221 tcctacagaa tatttaattg atagccaagg aaagattgga aagattcaat ttggtgctat
     2281 cagtaatgcg gatgcagaag cagcatttaa agaaatgaac tagaatcgat aaaatctgat
     2341 tacaagatgt agtcagattt tggtaacttc taaaactaac ttccagtttc ccacaaccta
     2401 gcttttagta tgagaaaaac gcgtgacatc agtggaaatc cgtcttagac taacttccac
     2461 tggttttctt tttcttgata tataagggtt caaaagcgaa aagactcaga aaaagtgcac
     2521 gacaaatagc cctaaaacag agtcgtctta gagtaacttc cagttttggg agagagatgg
     2581 aagttacttt gagaagttac ggtagtcaga tttttttaga aaaacatttt ataaatattc
     2641 acatatctcc tatatttatg gtaaaataga attatcagtt tattttggag tcaaagatga
     2701 atatatttag aacaaagaat gttagtttag ataaaacaga gatgcatagg catttgaagt
     2761 tatgggattt gattttgctg ggtatcggag ccatggtagg gacaggcgtc tttacaatca
     2821 caggtactgc agctgcaaca cttgctggcc cagccctagt gatttcaatc gttatttctg
     2881 ccttgtgtgt gggattatca gccctctttt ttgcagaatt tgcctcgcga gtacccgcta
     2941 caggaggtgc ctatagttac ctctatgcta tcttaggaga attccctgcc tggttggctg
     3001 gttggttaac catgatggag ttcatgacag ccatatcagg cgtagcttcg ggttgggcag
     3061 cttattttaa aggcttgctc tctcaatacg ggatagcctt tcctcaggct ttaaatggta
     3121 cctttaatcc tcaagcaggg acatttgttg atttattgcc tattcttgtc ttggtcttgg
     3181 tgacttcgct tgttttacta aatgccaagg cagccttacg ctttaattcg attctagtta
     3241 ttttgaaatt ttccgcttta gctctctttg ttttagtagg aatttggaat attaagtttg
     3301 ataattggag caattttgct ccttacggtt ttggacaaat ctatggagct agcactggta
     3361 ttatggctgg tgcgtccttg atgttcttcg gttttttggg atttgaatcc atctctatgg
     3421 ctgtagatga agtcaagact cctcaaaaaa atattcctag agggattgtc ttatcgcttt
     3481 ctatcgtaac cattctctat gccttggtga cccttgtttt gactggtgtg gttcactata
     3541 gtcatttaaa tgtcgatgat gccgttgcct ttgcccttcg tagtgttggg attagttggg
     3601 cagccaacta tgtgtcatta gtggctatct tgaccttgat tacagtttgt atttcgatga
     3661 cctatgccct atcgcgtatg atttacagtt tagcacgtga cggcttagtg cctgctgcct
     3721 ttaaggaact gacgaagact agcaagatac caaagaatgc tactatcttg acaggtctag
     3781 cttcagcagt agcagcagga atgttcccac tagccagtat tgcagccttt ttaaatattt
     3841 gtaccttagc ctacttgatc atgttggctt atggtctgat tcgcttacgg aaagaaaaag
     3901 gaatgcccaa agctggggaa tttaaaacac cattggtacc tctgttacca attttatcga
     3961 tcatcatttg tttatccttc atgttacagt ataatatgaa tacctggatt gctttcctag
     4021 ttgcgttgtt agtaggaagt attatttact tcacttatgg ctataagcat tctaccatag
     4081 aagaataaag tgaaagtcta ttgagttgtt gacactcagt agatttttat atgtgaaaga
     4141 aatttcaaat tttttctaaa aatatcttga cagattaaat tttcaggagt agaatattta
     4201 ctagttaatt aaatggttaa ggagttgttc atgaagaaac aaaatttatt tttagtcctg
     4261 ttaagtgtct ttcttttgtg cttgggggct tgtggtcaaa aggaaagtca gacaggaaag
     4321 gggatgaaaa ttgtgaccag tttttatcct atctacgcta tggttaagga agtatctggt
     4381 gacttgaatg atgttcggat gattcagtca agtagtggta ttcactcctt tgaaccttcg
     4441 gcaaatgata tcgcagccat ctatgatgca gatgtctttg tttaccattc tcatacactc
     4501 gaatcttggg caggaagtct ggatccaaat ctaaaaaaat ccaaagtgaa ggtcttagag
     4561 gcttctgagg gaatgacctt ggaacgtgtc cctggactag aggatgtgga agcaggggat
     4621 ggagttgatg aaaaaacgct ctatgaccct cacacatggc tagatcctga aaaagctgga
     4681 gaagaagccc aaattatcgc tgataaactt tcagaggtgg atagtgagca taaagagact
     4741 tatcaaaaaa atgcgcaagc ctttatcaaa aaagctcagg aattgactaa gaaattccaa
     4801 ccaaaatttg aaaaagcgac tcagaaaaca tttgtaacac aacatacagc cttttcttat
     4861 ctagcgaaga gatttgggct taatcaactt ggtattgcag gtatctctcc tgaacaagaa
     4921 ccaagtccac gacaactaac agaaattcag gaatttgtta agacctataa ggttaaaacg
     4981 atttttacag aaagtaacgc ttcttcaaaa gtagctgaaa ctcttgtcaa atcaacaggt
     5041 gtgggtctta aaactctgaa tcctttagag tcagacccac aaaatgacaa gacctattta
     5101 gaaaatcttg aagaaaatat gagtattcta gcagaagaat taaagtgagg aaagaatgaa
     5161 aattaataaa aaatatctag caggttcagt ggcagtcctt gccctaagtg tttgttccta
     5221 tgaacttggt cgtcaccaag ctggtcaggt taagaaagag tctaatcgag tttcttatat
     5281 agatggtgat caggctggtc aaaaggcaga aaacttgaca ccagatgaag tcagtaagag
     5341 ggaggggatc aacgccgaac aaatcgtcat caagattacg gatcaaggtt atgtgacctc
     5401 tcatggagac cattatcatt actataatgg caaggtccct tatgatgcca tcatcagtga
     5461 agagctcctc atgaaagatc cgaattatca gttgaaggat tcagacattg tcaatgaaat
     5521 caagggtggt tatgttatca aggtagatgg aaaatactat gtttacctta aggatgcagc
     5581 tcatgcggat aatattcgga caaaagaaga gattaaacgt cagaagcagg aacacagtca
     5641 taatcacggg ggtggttcta acgatcaagc agtagttgca gccagagccc aaggacgcta
     5701 tacaacggat gatgg
//
LOCUS       DAVFER010000074         5209 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1105170250
            SAMEA2167659-rid19724873.denovo.074, whole genome shotgun sequence.
ACCESSION   DAVFER010000074 DAVFER010000000
VERSION     DAVFER010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2167659
            Sequence Read Archive: ERR388902
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5209)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5209)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928716.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928716.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 04:07:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,118
            CDSs (total)                      :: 2,073
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 120
            CDSs (without protein)            :: 120
            Pseudo Genes (ambiguous residues) :: 0 of 120
            Pseudo Genes (frameshifted)       :: 67 of 120
            Pseudo Genes (incomplete)         :: 47 of 120
            Pseudo Genes (internal stop)      :: 34 of 120
            Pseudo Genes (multiple problems)  :: 23 of 120
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5209
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2167659-rid19724873.denovo.074"
                     /strain="1105170250"
                     /db_xref="taxon:1313"
     gene            complement(<1..2089)
                     /locus_tag="VU534_002013"
     CDS             complement(<1..2089)
                     /locus_tag="VU534_002013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec-dependent serine-rich glycoprotein
                     adhesin"
                     /protein_id="HEU1514541.1"
                     /translation="MFKVLRGGVDTTQVMTETVEDKVSHSITGLDILKGIVAAGAVIS
                     GTVATQTKVFTNESAVLEKTVEKTDALATNDTVVLGTISTSNSASSTSLSASESASTS
                     ASESASTSASTSASTSASESASTSASTSISASSTVVGSQTAAATEATAKKVEEDRKKP
                     ASDYVASVTNVNLQSYAKRRKRSVDSIEQLLASIKNAAVFSGNTIVNGAPAINASLNI
                     AKSETKVYTGEGVDSVYRVPIYYKLKVTNDGSKLTFTYTVTYVNPKTNDLGNISSMRP
                     GYSIYNSGTSTQTMLTLGSDLGKPSGVKNYITDKNGRQVLSYNTSTMTTQGSGYTWGN
                     GAQMNGFFAKKGYGLTSSWTVPITGTDTSFTFTPYAARTDRIGINYFNGGGKVVESST
                     TSQSLSQSKSLSVSASQSASASASTSASASASTSASASASTSASASASTSASVSASTS
                     ASASASTSASASASTSASESASTSASASASTSASASASTSASASASTSASESASTSAS
                     ASASTSASESASTSASASASTSASASASTSASGSASTSTSASASTSASASASTSASAS
                     ASTSASASASASTSASASTSASASASTSASASASTSASASASTSASASTSASESASTS
                     ASASASTSASASASTSASASASTSASESASTSASASASTSASASASTSASASASTSAS
                     ASASTSASASASIS"
     gene            complement(2087..2200)
                     /locus_tag="VU534_002014"
                     /pseudo
     CDS             complement(2087..2200)
                     /locus_tag="VU534_002014"
                     /inference="COORDINATES: protein motif:HMM:TIGR03715.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="KxYKxGKxW signal peptide domain-containing
                     protein"
     gene            complement(2443..2904)
                     /locus_tag="VU534_002015"
     CDS             complement(2443..2904)
                     /locus_tag="VU534_002015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000514209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU1514542.1"
                     /translation="MGKERRKQGNLERKKRVVKKRKIPLEELKAFVEAHPDAFLREIA
                     ARFDCALPSVWAVLKQIKVILKKTTSFREQKPEKVSEFLDILDNLKDLPVLYIDETGI
                     DRYLYRPYAGAPRGEKVYGKISGRRFERTNEVEQKLNGSFLIRYIDSQIRE"
     gene            complement(2871..2972)
                     /locus_tag="VU534_002016"
     CDS             complement(2871..2972)
                     /locus_tag="VU534_002016"
                     /inference="COORDINATES: protein motif:HMM:NF013842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1514543.1"
                     /translation="MKGGHRHVEAAKVFDVGVRTLFTWEKKDVNKGT"
     gene            3281..3661
                     /locus_tag="VU534_002017"
     CDS             3281..3661
                     /locus_tag="VU534_002017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEU1514544.1"
                     /translation="MTYLEKWFDFNRRQKEIESLLEETIAQQSEQSLTLKEFYLLYYL
                     DLAEEKSLRQIDLPDKLHLSPSAVSRMVARLEAKNCGLLSRMCCHQDRRSSFICLTND
                     GQKTLASLQKTVEESLEAGLDFLI"
     gene            3760..3981
                     /locus_tag="VU534_002018"
     CDS             3760..3981
                     /locus_tag="VU534_002018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4649 family protein"
                     /protein_id="HEU1514545.1"
                     /translation="MIEITYIDASKNERTVTFESYEDFERSQQACLIGVADYYPVQKL
                     TYKGHNLDYHGTYGDIFFYLMKQDLSQYN"
     gene            3998..4312
                     /gene="trxA"
                     /locus_tag="VU534_002019"
     CDS             3998..4312
                     /gene="trxA"
                     /locus_tag="VU534_002019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003004519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HEU1514546.1"
                     /translation="MAKAITDATFEQETKDGLVLVDFWATWCGPCRMQGPILDKLSEE
                     LSEDVLKIVKMDVDENPNTARAFGIMSIPTLLFKKDGQVVKQVAGVHTAEQIKAIIAE
                     LS"
     gene            4618..5151
                     /gene="queF"
                     /locus_tag="VU534_002020"
     CDS             4618..5151
                     /gene="queF"
                     /locus_tag="VU534_002020"
                     /EC_number="1.7.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent 7-cyano-7-deazaguanine reductase
                     QueF"
                     /protein_id="HEU1514547.1"
                     /translation="MKRQLALVVFSGGQDSTTCLFWVMQHYETVEAVTFAYGQRHHLE
                     IQITREIAKEQGIRHHILDMSLLGQITAQPDFATIHISYIPDKLCVESKSLKLYLFSY
                     RNHGDFHENCINTIGKDLVNLLDPRYLEVWGKFTPRGGISIDPYYNYGKQGTKYEGLA
                     EQRLFQHDLYPEKIDNR"
BASE COUNT         1490 a         1100 c         1094 g         1525 t
ORIGIN      
        1 ctgagatact tgctgaggct gacgcactgg ttgaggctga ggctgaggcg ctagtacttg
       61 ctgaagccga cgcactggtg cttgctgaag ccgaggcact tgttgatgcg gaagctgacg
      121 cactggtact tgctgactct gatgcactgg ttgacgccga agccgatgca ctcgttgatg
      181 ctgaagctga tgcactagta cttgctgagg ctgacgcact ggttgatgcc gattcagatg
      241 cactggttga ggccgacgca cttgtcgacg ctgaggctga agcactggta cttgctgaag
      301 ctgaggcgct tgtcgatgct gaggctgacg cactggtact tgctgaagct gaggtacttg
      361 cgcttgctga ggccgacgca ctcgttgatg ctgaggctga agcacttgtt gatgctgagg
      421 ctgaagcact ggttgacgct gaagctgacg tactcgttga tgctgaaccc gaggcgcttg
      481 tgcttgctga agccgaagca ctcgttgatg ctgaggctga ggcgctggtt gaggccgatt
      541 cagaagctga ggtgcttgct gaggccgagg cgctggttga ggccgattca gaagctgagg
      601 tgcttgctga ggccgaggcg ctggttgatg ctgaagctga agcactggta cttgctgaag
      661 ccgaagcact ggttgacgct gattcagatg ctgatgtgct tgctgaagcc gaggcacttg
      721 tcgatgctga ggctgaagca cttgttgatg ctgagactga agcactggta cttgctgaag
      781 ctgacgcact ggttgacgct gaagccgagg cactggttga tgctgaagcc gacgcacttg
      841 ttgatgctga agctgaggcg ctttgactag cacttactga gagtgactta gactgtgaaa
      901 gtgactgact ggtcgtgcta gattcaacta cctttcctcc accattgaag tagttaattc
      961 caattctatc tgttctagca gcgtaagggg taaatgtaaa ggatgtatcc gttccagtaa
     1021 ttggtacagt ccaagatgat gttaatccat atcctttctt agcaaagaaa ccattcattt
     1081 gggcaccatt tccccaagta tacccactac cctgcgtcgt cattgtagat gtattatagg
     1141 atagaacctg tctaccattt ttgtcagtaa tgtagttctt tacacctgaa ggtttaccaa
     1201 gatcactgcc aagggttaac attgtttgtg ttgaagtacc tgaattatag atagaatatc
     1261 caggacgcat acttgatata ttaccaagat catttgtttt aggattcaca tacgtaaccg
     1321 tataggtaaa ggtcaatttt gaaccatcat ttgtcacttt caatttatag taaattggaa
     1381 cacgatatac cgaatctaca ccttcacctg tataaacttt tgtctcactt ttagcaatgt
     1441 ttagacttgc attaattgca ggggcgccat ttacaatcgt attgccagaa aaaacagcag
     1501 cattttttat agaagccagc aattgctcga tggaatccac tgaacgcttg cgtcgcttag
     1561 cataagattg gagattgaca tttgtaactg atgctacata atcactagct ggtttcttac
     1621 gatcttcttc gaccttctta gcagttgctt ctgtagcggc agctgtttgt gaacctacca
     1681 cagtagatga tgcagaaata cttgtcgaag ccgatgtact tgctgattct gatgcacttg
     1741 tacttgctga ggtcgaagcg ctggttgagg ctgactcaga tgcagatgta cttgccgact
     1801 ctgaagctga caaactagtt gaactcgctg aattacttgt agatatcgta cctagaacta
     1861 ctgtatcatt tgttgccaaa gcatccgttt tctctacagt tttttcaagt actgctgact
     1921 catttgtaaa taccttcgtt tgagttgcaa cggttccact tatgacagct cccgcagcaa
     1981 ctatcccctt gaggatatca agcccagtaa ttgaatgact tactttatct tctaccgttt
     2041 cggtcatgac ctgagtagta tcaacaccac ctcgcaagac cttaaacaag ccaaaaagag
     2101 aagtcgaggc ccgtagccaa tgcttccctg atttgattaa tttgaaccga gttactcggt
     2161 ctgtttctct atattcaccc ttctgacgtc taaaaaatat tttgaaattt cctttcgagt
     2221 attattttca tgtatggata taaataaatt accatactat aattatagaa tagggaaccc
     2281 aaaatagcaa gaaacttgag gtatttttgc taaaaaaaaa agcattttac tattttgtat
     2341 atatatatat attataagat aagtttttta taaagacacg caaatgagta taaatcagct
     2401 aatttttggt ttatattcct atttttatgc ataattattc tttcattctc taatttgtga
     2461 atcaatatat ctgattagaa aactaccatt gagtttttgc tccacctcat tagtccgctc
     2521 aaaacgccgt ccgctaatct tgccatagac tttctcccct ctaggagccc ctgcataagg
     2581 acgatagagg tagcggtcga ttcccgtttc gtcaatatat aggactggta aatcttttag
     2641 gttatccaaa atatcaagaa actcagaaac tttctcaggc ttttgttccc taaaactggt
     2701 cgtctttttt aaaatgacct taatctgctt taaaactgcc catacggagg gcaaagcaca
     2761 atcaaaacgg gccgcaattt cccgtaaaaa agcgtctgga tgagcctcta caaaggcttt
     2821 caattcttct aaagggatct tacgcttttt gacgactcgc tttttccgct ctaagttccc
     2881 ttgtttacgt ctttcttttc ccacgtgaag agagttctga cgccgacatc aaaaactttg
     2941 gccgcctcga catgtctgtg ccctccttta atggaatcta atgctccttg tttaaaatca
     3001 gtactatatg catagcttta ttagaccatg cttattttaa actaagcaac tatagataga
     3061 gaaatgaaat aaaatctgaa ttcgaatgtg ataaggagtt agaaattgaa acaataggat
     3121 tcccccatta ttcacacaaa aataaaacca ctaaaaaaca gagcttgcca gcattcttga
     3181 aaagtagtat aattattgca tgcgcaatca tcttgtgacg cagagactgc ccgttaatgg
     3241 actttcttct atttatgact ctaaaaagaa aggagacact atgacctatt tggaaaaatg
     3301 gtttgacttc aatcggcgtc agaaagaaat tgaaagtctc ttggaagaga ccattgccca
     3361 acagagcgag caaagtctga ccttgaaaga gttctacctg ctctactatc tggacttggc
     3421 tgaagaaaaa tctctacgcc agattgacct gccagataag cttcatctga gcccgagcgc
     3481 agtttctagg atggtggctc gcttggaagc taaaaattgc ggtctactca gtcgcatgtg
     3541 ttgccatcaa gatagacgct ctagttttat ctgcctgaca aatgatgggc aaaagacact
     3601 ggcctcgcta caaaagactg tcgaagaaag cttggaagca ggtttggatt tcttgattta
     3661 agatgatttt aaaaaaagtt gcgtgcgcaa tcatttttct tgacattctc ttttataagg
     3721 agtaaaataa agttagcatt aaacaaagga gttttaaaca tgattgaaat tacctatata
     3781 gatgccagca agaacgaaag aactgtgact ttcgagtctt atgaagactt tgaacgttcg
     3841 caacaagctt gccttatcgg cgtcgcagac tactaccctg tccaaaaatt aacttacaag
     3901 ggtcataatt tggactacca tgggacttat ggagatatct tcttctatct catgaaacaa
     3961 gatttaagcc aatataacta aaaaaaggag aaatacaatg gcaaaagcaa ttacagatgc
     4021 aacattcgaa caagaaacaa aagacggttt ggtcttagta gacttctggg caacttggtg
     4081 tggtccatgt cgtatgcaag gtccaatctt ggacaaattg tctgaagaac tttcagaaga
     4141 tgtcttgaaa atcgttaaaa tggacgttga tgaaaatcca aacacagctc gtgcttttgg
     4201 aatcatgtct attccaactc ttctcttcaa aaaagacggc caagttgtca aacaagttgc
     4261 aggtgttcac acagcagaac aaatcaaggc catcattgct gaattgagct aatcaaacga
     4321 gagaccaagt actttctttg gtctcttttt tcttgccctt tgccattttt caaaaaatat
     4381 gctagactat agtagattga aactagaata gtacacctct acttctaaaa cattgttaga
     4441 aatcgatttg actgtcctga tcgatttgtc ctgttcttat ttcattttac tatataagta
     4501 gaatattacg atgtttggga tatgccatcg ctaaaaaaac ctcgatttgg tattttttag
     4561 ctccctaatg ggagcttttt gcgtgctctg aacatttccc attttggaag gagtactatg
     4621 aaacgtcaat tagccttggt cgtctttagt ggtggtcaag attcaacaac ctgccttttc
     4681 tgggtcatgc aacactatga aacagtcgaa gctgtcacct ttgcctacgg ccaacgtcat
     4741 cacctcgaaa ttcaaattac tagagaaatc gctaaggaac agggcattcg tcaccatatc
     4801 ctcgatatgt ctctgctggg acaaatcact gctcagccag actttgcgac gattcatatt
     4861 tcctacattc ctgacaagct ctgtgtcgag tcaaaatccc tcaaactata tctatttagc
     4921 taccgaaacc acggagattt ccacgaaaac tgtatcaaca ccatcgggaa agacttggtc
     4981 aacttgctag accctcgcta tttagaagtc tggggaaaat tcactccgcg cggtggcatt
     5041 tcaatcgacc cctactacaa ctacggtaag caaggaacta agtatgaggg cttggcagaa
     5101 caacgcctct tccaacacga cctttatcca gagaaaattg acaaccgcta aagtcatact
     5161 caatgaaaat caaagagcaa actaggaagt tagccgcagg ttgctcaaa
//
LOCUS       DAVFER010000075         4915 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1105170250
            SAMEA2167659-rid19724873.denovo.075, whole genome shotgun sequence.
ACCESSION   DAVFER010000075 DAVFER010000000
VERSION     DAVFER010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2167659
            Sequence Read Archive: ERR388902
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4915)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4915)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928716.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928716.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 04:07:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,118
            CDSs (total)                      :: 2,073
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 120
            CDSs (without protein)            :: 120
            Pseudo Genes (ambiguous residues) :: 0 of 120
            Pseudo Genes (frameshifted)       :: 67 of 120
            Pseudo Genes (incomplete)         :: 47 of 120
            Pseudo Genes (internal stop)      :: 34 of 120
            Pseudo Genes (multiple problems)  :: 23 of 120
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4915
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2167659-rid19724873.denovo.075"
                     /strain="1105170250"
                     /db_xref="taxon:1313"
     gene            100..462
                     /locus_tag="VU534_002021"
     CDS             100..462
                     /locus_tag="VU534_002021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1514548.1"
                     /translation="MLEVGLNFLISLFTFTFDILYPIVKVGHTDDYSHGAVKLSVSLV
                     DKDAMKKIFVTVIGYFEINIDENITDILYVNGTAILYLYLRSIVSIVSAIDSSEAMLL
                     PIINVLELLDKSQPFEEE"
     gene            1507..2499
                     /locus_tag="VU534_002022"
     CDS             1507..2499
                     /locus_tag="VU534_002022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEU1514549.1"
                     /translation="MAMIEVEHLQKNFVKTVKEPGLKGALRSFIHPEKQTFEAVKDLT
                     FEVPKGQILGFIGANGAGKSTTIKMLTGILKPTSGFCRINGKIPQDNRQDYVKDIGVV
                     FGQRTQLWWDLALQETYTVLKEIYDVPDSLFHKRMDFLNEVLDLKDFIKDPVRTLSLG
                     QRMRADIAASLLHNPKVLFLDEPTIGLDVSVKDNIRRAITQINQEEETTILLTTHDLS
                     DIEQLCDRIFMIDKGQEIFDGTVSQLKETFGKMKTLSFELLPGQSHLVSHYDGLSDMT
                     IDRQGNSLNIEFDSSRYQSADIIKQTLSDFEIRDLKMVDTDIEDIIRRFYRKEL"
     gene            2501..3319
                     /locus_tag="VU534_002023"
     CDS             2501..3319
                     /locus_tag="VU534_002023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000240175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 family transporter protein"
                     /protein_id="HEU1514550.1"
                     /translation="MIKLWRRYKPFINAGVQELITYRVNFILYRIGDVMGAFVAFYLW
                     KAVFDSSQESLIQGFSMADITLYIIMSFVTNLLTRSDSSFMIGEEVKDGSIIMRLLRP
                     VHFAASYLFTELGSKWLIFISVGLPFLSVIVLMKIISGQGIVEVLGLTVIYLFSLTLA
                     YLINFFFNICFGFSAFVFKNLWGSNLLKTSIVAFMSGSLIPLAFFPKVVSDILSFLPF
                     SSLIYTPVMIIVGKYDASQILQALLLQFFWLLVMVGLSQLIWKRVQSFITIQGG"
     gene            3321..4106
                     /locus_tag="VU534_002024"
     CDS             3321..4106
                     /locus_tag="VU534_002024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU1514551.1"
                     /translation="MKKYQRMHLIFIRQYIKQIMEYKVDFVVGVLGVFLTQGLNLLFL
                     NVIFQHIPFLEGWTFQEIAFIYGFSLIPKGMDHLFFDNLWALGQRLVRKGEFDKYLTR
                     PINPLFHILVETFQIDALGELLVGGILLGTTVTSIVWTLPKFLLFLVCIPFATLIYTS
                     LKIATASIAFWTKQSGAMIYIFYMFNDFAKYPISIYNSLLRWLISFIVPFAFTAYYPA
                     SYFLQEKDVFFNVGGLMLISLVFFVISLKLWDKGLDSYESAGS"
     gene            4145..4423
                     /locus_tag="VU534_002025"
     CDS             4145..4423
                     /locus_tag="VU534_002025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family acetyltransferase"
                     /protein_id="HEU1514552.1"
                     /translation="MFVIEEVKDENQKKAVVAEVLKDLPEWFGIPESTQAYIEGTTTL
                     QVWTAYQESDLTRFVSLSYSSEDCAEIDCLGVKKLIKVEKLGANCLLL"
     gene            4408..4605
                     /locus_tag="VU534_002026"
     CDS             4408..4605
                     /locus_tag="VU534_002026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU1514553.1"
                     /translation="MLATLESEARKKVGYLQVKTVAEGSNKDYDRTNDFYRGLGFKKL
                     EIFPQLWNPQNPCQILIKKLE"
BASE COUNT         1415 a          807 c         1029 g         1664 t
ORIGIN      
        1 ctgactacgt cagttccatc tacaacctca aaacagtgtt ttgagcaacc tgcggctagt
       61 ttcctagttt gctctttggt tttcattgag tataacacat tgttagaagt tggtttaaat
      121 ttcctaatca gtttgttcac atttaccttc gatatattat atcccatagt taaggttggt
      181 catacagatg attatagtca tggagccgta aaacttagtg tttctttagt tgacaaagat
      241 gccatgaaaa aaatatttgt aactgtaata ggatattttg aaataaatat agatgaaaat
      301 atcaccgata ttctatacgt aaatggtact gctattcttt atctttattt acgttcaatt
      361 gtttcaatag tttcggcaat tgatagcagt gaagcaatgt tgctacctat cattaatgtt
      421 ttagagttac tagataaatc tcaacctttt gaagaagaat aatttattag ctcactaaat
      481 tgagggtaag gaaaagtaaa agcagtaaga aaaatgtctt gcattataca gcaacctttt
      541 gggaatgagt ggatggattg aataaaattt gattaagagt ggatgattta tctgtagatt
      601 attattggac agttagtctt gaagtagtct aagaattagg ttataatcag tagaagcctt
      661 gctaataatg aggaggttag tttatgtata gtagactgaa tctaaaatag tacgaaacaa
      721 ttgctaaaat atttatagaa attaatttta ctttcccaat cgatttgttc tcatcttatt
      781 tcaatccgct atatattatg gtatcgaatc ttcatcagaa tgataaaatt aatcaattga
      841 tatctgatta caaacagaat atgaaagctt tttatatcac tattgaaaaa tttatacgag
      901 atgatgaaag ccttaagtgt tattttataa aggttatttc aagtcgttcc aaggtaacaa
      961 gtctagatca gattgaagct gataaaacga tacaaagaaa atattcaagt gagctaaaaa
     1021 aatttattgg attttataat gagattattt gtgaggaaaa tagtttccta catgtacgaa
     1081 agaggtggtc gagttggttt aggtagtcga tgcgtgagtt gataattctc agggtatgga
     1141 cttctttttc atgaatgagg taaaagagca ggtattgttt agagacaatc attctgagca
     1201 tattttctgg atagagggag tatccgattt tatgatcaaa gttaataccg ccctctggtg
     1261 agaagatgag taggttggta atttaaacta ttaaacagaa tttttgatta aaagtattat
     1321 ttcatgagag aaatcctaat ttcacaatcc ataggcaaac gcttgcattt cgttttttat
     1381 tggactataa taggttggta taaagccttc tgtagtaata aaatgtagaa ggtgtagaaa
     1441 gtaaggattt agaatatttg tagttaaaaa cacaatgttg ctattcctta cgatagggag
     1501 atagatatgg caatgataga agtggaacat cttcagaaaa attttgtgaa gactgttaag
     1561 gaaccgggct tgaagggggc tttgcgctcc tttattcatc ctgaaaagca gacctttgaa
     1621 gcggtcaagg atttgacctt tgaggttcca aaagggcaga ttttaggatt tatcggggca
     1681 aatggtgctg ggaagtcgac aaccattaaa atgctgacag gaattttgaa accaacatct
     1741 ggtttttgtc ggattaacgg caagattccc caggacaatc ggcaagatta tgtcaaagat
     1801 attggcgtag tctttggaca acgcacccag ctatggtggg atttggctct gcaagagacc
     1861 tacactgtct taaaagagat ttatgatgtg ccagactcgc tctttcataa gcgtatggac
     1921 tttttgaatg aagtcttgga tttgaaggac tttatcaagg atcccgtgcg gactctttca
     1981 ctgggacaac ggatgcgggc ggatattgcg gcctccttgc tccacaatcc caaggttctt
     2041 tttttagatg agccgaccat tggtttggac gtttcggtta aggataatat tcgtcgggca
     2101 attactcaga tcaatcaaga ggaagaaact accattcttt tgaccactca cgatttgagt
     2161 gatattgagc aactttgtga tcggattttc atgattgaca aggggcaaga gatttttgat
     2221 ggaacggtga gccaactcaa ggagaccttt ggtaagatga agactctctc ttttgaactg
     2281 ctaccaggtc aaagtcatct cgtctctcac tatgacggtc tgtctgatat gaccattgat
     2341 agacaaggaa acagcctcaa cattgaattt gatagttctc gctaccagtc agctgacatt
     2401 atcaagcaaa ccctgtctga ttttgaaatc cgcgatttga agatggtgga tacggatatt
     2461 gaggatatta tccgtcgctt ctaccgaaag gagctctagg atgatcaaat tgtggagacg
     2521 ttataaaccc tttatcaatg caggggttca ggagttgatt acttaccgag tcaactttat
     2581 tctctatcgg attggcgatg tcatgggggc ttttgtggcc ttttatctct ggaaggctgt
     2641 ctttgattct tcgcaagagt ctttgattca gggcttcagt atggcggata tcaccctcta
     2701 catcatcatg agttttgtga ccaatcttct gactagatcc gattcgtcct ttatgattgg
     2761 ggaggaggtc aaggatggct ccattatcat gcgtttgttg cgaccagtgc attttgcggc
     2821 ctcctatctt ttcaccgagc ttggttccaa gtggttgatt tttatcagcg ttggccttcc
     2881 atttttaagt gtcattgtct tgatgaaaat catatcgggt caaggtattg tagaggtgct
     2941 aggattaact gtcatttatc tttttagctt aacgctcgcc tatctgatta actttttctt
     3001 taatatttgc tttggatttt cagcctttgt gtttaaaaat ctttggggtt ccaacctact
     3061 taagacttcc atagtggctt ttatgtcggg gagtttgatt cccttggcat tttttccaaa
     3121 ggttgtttca gatattctct cctttttgcc tttttcatcc ttgatttata ctccagttat
     3181 gatcattgtt ggaaaatacg atgccagtca gattcttcag gcactccttt tgcagttctt
     3241 ctggctctta gtgatggtgg gattgtctca gttaatttgg aaacgggtcc agtcctttat
     3301 caccattcaa ggaggttagt atgaaaaaat atcaacgaat gcatctgatt tttatcagac
     3361 aatacatcaa acaaatcatg gaatataagg tagattttgt ggttggtgtc ttgggagtct
     3421 ttctgactca aggcttgaat ctcttgtttc tcaatgtcat ctttcaacat attccattcc
     3481 tagaaggctg gacctttcaa gagatagctt tcatttatgg attttccttg attcccaagg
     3541 gaatggacca tctctttttt gacaatctct gggcactagg gcaacgccta gtccgaaaag
     3601 gggagtttga caagtatctg actcgtccca tcaatcctct ctttcacatc ctagttgaaa
     3661 cctttcagat tgatgccttg ggtgaactct tagtcggtgg tattttattg ggaacaacag
     3721 tgaccagcat tgtttggact cttccaaaat tcctgctttt cctagtttgt attccttttg
     3781 cgaccttgat ttatacttct cttaaaatcg caacagccag tatcgccttt tggactaagc
     3841 agtcaggcgc catgatttac atcttctata tgttcaatga ctttgctaag tatccgattt
     3901 ctatttacaa ttctcttctt cgttggttga ttagctttat cgtgcctttc gcctttacag
     3961 cctactatcc agctagctat ttcttacagg aaaaggatgt gttctttaac gtaggaggtt
     4021 tgatgttgat ttctctggtt ttctttgtta tttcccttaa actttgggat aagggcttag
     4081 attcctacga aagtgcgggt tcgtaaaagc taaagtaaga ctaaaatcaa gaaagaaact
     4141 tatgatgttt gtaattgaag aagtcaagga tgaaaatcaa aaaaaggcag ttgtcgctga
     4201 ggttttgaag gatttgccag aatggtttgg aatcccagaa agcacacaag cctatataga
     4261 aggaaccacg acactgcaag tttggaccgc ctatcaggag agtgatttga ctagatttgt
     4321 aagcttatcc tattcgagtg aagattgtgc agagattgat tgtctcggcg taaaaaagct
     4381 tatcaaggta gaaaaattgg gagccaattg cttgctactt tagagagtga agctcgtaaa
     4441 aaagttggtt atctgcaggt caaaacagtg gcagaaggtt ctaataaaga ttatgatcga
     4501 acaaatgact tttatcgagg tcttggcttt aaaaagttag agatttttcc tcaactatgg
     4561 aatccgcaaa atccttgtca gattttgatt aaaaagcttg aataatatta cttgacatct
     4621 attctcagag tgctatactg taagtgtaat cgccgattta gcttagttgg tagagcaagg
     4681 cactcgtaaa gcctaggtta taggtagata aacgactgag gatttgaaaa aatagatagg
     4741 tagaagataa ccgttaagcc ttactcttag cggttattta tattgtttaa tagcgctaat
     4801 attttatcaa ttatgcctgt tttcgtgttt ctggtagttg ttcaagttta ttgctactat
     4861 ttttgatggt atgaatgtgc ttataatgta tcccggttaa cgaaagtttt ggact
//
LOCUS       DAVFER010000076         4848 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1105170250
            SAMEA2167659-rid19724873.denovo.076, whole genome shotgun sequence.
ACCESSION   DAVFER010000076 DAVFER010000000
VERSION     DAVFER010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2167659
            Sequence Read Archive: ERR388902
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4848)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4848)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928716.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928716.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 04:07:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,118
            CDSs (total)                      :: 2,073
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 120
            CDSs (without protein)            :: 120
            Pseudo Genes (ambiguous residues) :: 0 of 120
            Pseudo Genes (frameshifted)       :: 67 of 120
            Pseudo Genes (incomplete)         :: 47 of 120
            Pseudo Genes (internal stop)      :: 34 of 120
            Pseudo Genes (multiple problems)  :: 23 of 120
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4848
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2167659-rid19724873.denovo.076"
                     /strain="1105170250"
                     /db_xref="taxon:1313"
     gene            <1..1526
                     /locus_tag="VU534_002027"
     rRNA            <1..1526
                     /locus_tag="VU534_002027"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
     gene            1578..1650
                     /locus_tag="VU534_002028"
     tRNA            1578..1650
                     /locus_tag="VU534_002028"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1611..1613,aa:Ala,seq:tgc)
     gene            1775..4676
                     /locus_tag="VU534_002029"
     rRNA            1775..4676
                     /locus_tag="VU534_002029"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
     gene            4753..>4848
                     /gene="rrf"
                     /locus_tag="VU534_002030"
     rRNA            4753..>4848
                     /gene="rrf"
                     /locus_tag="VU534_002030"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
BASE COUNT         1345 a          997 c         1438 g         1068 t
ORIGIN      
        1 ggctcaggac gaacgctggc ggcgtgccta atacatgcaa gtagaacgct gaaggaggag
       61 cttgcttctc tggatgagtt gcgaacgggt gagtaacgcg taggtaacct gcctggtagc
      121 gggggataac tattggaaac gatagctaat accgcataag agtagatgtt gcatgacatt
      181 tgcttaaaag gtgcacttgc atcactacca gatggacctg cgttgtatta gctagttggt
      241 ggggtaacgg ctcaccaagg cgacgataca tagccgacct gagagggtga tcggccacac
      301 tgggactgag acacggccca gactcctacg ggaggcagca gtagggaatc ttcggcaatg
      361 gacggaagtc tgaccgagca acgccgcgtg agtgaagaag gttttcggat cgtaaagctc
      421 tgttgtaaga gaagaacgag tgtgagagtg gaaagttcac actgtgacgg tatcttacca
      481 gaaagggacg gctaactacg tgccagcagc cgcggtaata cgtaggtccc gagcgttgtc
      541 cggatttatt gggcgtaaag cgagcgcagg cggttagata agtctgaagt taaaggctgt
      601 ggcttaacca tagtaggctt tggaaactgt ttaacttgag tgcaagaggg gagagtggaa
      661 ttccatgtgt agcggtgaaa tgcgtagata tatggaggaa caccggtggc gaaagcggct
      721 ctctggcttg taactgacgc tgaggctcga aagcgtgggg agcaaacagg attagatacc
      781 ctggtagtcc acgctgtaaa cgatgagtgc taggtgttag accctttccg gggtttagtg
      841 ccgtagctaa cgcattaagc actccgcctg gggagtacga ccgcaaggtt gaaactcaaa
      901 ggaattgacg ggggcccgca caagcggtgg agcatgtggt ttaattcgaa gcaacgcgaa
      961 gaaccttacc aggtcttgac atccctctga ccgctctaga gatagagctt tccttcggga
     1021 cagaagtgac aggtggtgca tggttgtcgt cagctcgtgt cgtgagatgt tgggttaagt
     1081 cccgcaacga gcgcaacccc tattgttagt tgccatcatt tagttgggca ctctagcgag
     1141 actgccggta ataaaccgga ggaaggtggg gatgacgtca aatcatcatg ccccttatga
     1201 cctgggctac acacgtgcta caatggctgg tacaacgagt cgcaagccgg tgacggcaag
     1261 ctaatctctt aaagccagtc tcagttcgga ttgtaggctg caactcgcct acatgaagtc
     1321 ggaatcgcta gtaatcgcgg atcagcacgc cgcggtgaat acgttcccgg gccttgtaca
     1381 caccgcccgt cacaccacga gagtttgtaa cacccgaagt cggtgaggta accgtaagga
     1441 gccagccgcc taaggtggga tagatgattg gggtgaagtc gtaacaaggt agccgtatcg
     1501 gaaggtgcgg ctggatcacc tcctttctaa ggataaggaa ctgcgcattg gtcttgttta
     1561 gtcttgagag gtcttgtggg gccttagctc agctgggaga gcgcctgctt tgcacgcagg
     1621 aggtcagcgg ttcgatcccg ctaggctcca ttggtgagag atcaccaagt aatgcacatt
     1681 gaaaattgaa tatctatatc aaatagtaac aagaaaataa accgaaaacg ctgtagtatt
     1741 aataagagtt tatgactgaa aggtcagaaa ataaggttaa gttaataagg gcgcacggtg
     1801 gatgccttgg cactaggagc cgacgaagga cgtgacaaac gacgatatgc cttgggtagc
     1861 tgtaagtaag cgatgatcca gggatttccg aatgggggaa cccaacaggt aatacctgtt
     1921 acccacatct gttaaggatg tgaggaggaa gacgcagtga actgaaacat ctaagtagct
     1981 gcaggaagag aaagcaaaag cgattgcctt agtagcggcg agcgaaacgg cagaagggca
     2041 aaccgaagag tttactcttc ggggttgtag gactgcaatg tggactcaaa gattatagaa
     2101 gaatgatttg ggaagatcag ccaaagagag taatagcctc gtatttaaaa tagtctttgt
     2161 acttagcagt atcctgagta cggcgggaca cgtgaaatcc cgtcggaatc tgggaggacc
     2221 atctcccaac cctaaatact ccctagtgac cgatagtgaa ccagtaccgt gagggaaagg
     2281 tgaaaagcac cccgggaggg gagtgaaata gaacctgaaa ccgtgtgcct acaacaagtt
     2341 cgagcccgtt aatgggtgag agcgtgcctt ttgtagaatg aaccggcgag ttacgttatg
     2401 atgcgaggtt aagttgaaga gacggagccg tagggaaacc gagtctgaat agggcgcctt
     2461 agtatcatga cgtagacccg aaaccatgtg acctacccat gagcaggttg aaggtgcggt
     2521 aagacgcact ggaggaccga accagggcac gttgaaaagt gcttggatga cttgtgggta
     2581 gcggagaaat tccaaacgaa cttggagata gctggttctc tccgaaatag ctttagggct
     2641 agcgtcgaca ttagagattc ttggaggtag agcactgttt gggtgagggg tccatcccgg
     2701 attaccaatc tcagataaac tccgaatgcc aatgaattat ggtcggcagt cagactgcga
     2761 gtgctaagat ccgtagtcga aagggaaaca gcccagacca ccagctaagg tcccaaaata
     2821 attgttaagt ggaaaaggat gtggggttgc acagacaact aggatgttag cttagaagca
     2881 gctattcatt caaagagtgc gtaatagctc actagtcgag tgaccctgcg ccgaaaatgt
     2941 accggggcta aaacaattta ccgaagctgt ggataccttt ataggtatgg taggagagcg
     3001 ttctatgtgt gatgaaggta taccgtgagg agtgctggaa cgcatagaag tgagaatgcc
     3061 ggtatgagta gcgaaagaca ggtgagaatc ctgtccaccg taagactaag gtttccaggg
     3121 gaaggctcgt ccgccctggg ttagtcggga cctaaggaga gaccgaaagg tgtatccgat
     3181 ggacaacagg ttgatattcc tgtactagag tatgtagtga tggagggacg cagtaggcta
     3241 actaaagcag acgattggaa gagtctgtct aagcagtgag gtgtgaattg agtcaaatgc
     3301 ttaattctat aacattgagc tgtgatgggg agcgaagttt agtagcgaag ttagtgacgt
     3361 cacactgcca agaaaagctt ctagcgttta aacatactct acccgtaccg caaaccgaca
     3421 caggtagtcg aggcgagtag cctcaggtga gcgagagaac tctcgttaag gaactcggca
     3481 aaatgacccc gtaacttcgg gagaaggggt gctgacttaa agtcagccgc agtgaatagg
     3541 cccaagcaac tgtttatcaa aaacacagct ctctgctaaa tcgtaagatg atgtataggg
     3601 ggtgacgcct gcccggtgct ggaaggttaa gaggagtgct tagcgtaagc gaaggtatga
     3661 attgaagccc cagtaaacgg cggccgtaac tataacggtc ctaaggtagc gaaattcctt
     3721 gtcgggtaag ttccgacccg cacgaaaggc gtaatgattt gggcactgtc tcaacgagag
     3781 actcggtgaa attttagtac ctgtgaagat gcaggttacc cgcgacagga cggaaagacc
     3841 ccatggagct ttactgcagt ttgatattga gtgtctgtac cacatgtaca ggataggtag
     3901 gagtctaaga gatcgggacg ccagtttcga aggagacgct gttgggatac tacccttgtg
     3961 ttatggccac tctaacccag ataggtgatc cctatcggag acagtgtctg acgggcagtt
     4021 tgactggggc ggtcgcctcc taaaaggtaa cggaggcgcc caaaggttcc ctcagaatgg
     4081 ttggaaatca ttcgcagagt gtaaaggtat aagggagctt gactgcgaga gctacaactc
     4141 gagcagggac gaaagtcggg cttagtgatc cggtggttcc gtatggaagg gccatcgctc
     4201 aacggataaa agctaccctg gggataacag gcttatctcc cccaagagtt cacatcgacg
     4261 gggaggtttg gcacctcgat gtcggctcgt cgcatcctgg ggctgtagtc ggtcccaagg
     4321 gttgggctgt tcgcccatta aagcggcacg cgagctgggt tcagaacgtc gtgagacagt
     4381 tcggtcccta tccgtcgcgg gcgtaggaaa tttgagagga tctgctccta gtacgagagg
     4441 accagagtgg acttaccgct ggtgtaccag ttgtcttgcc aaaggcatcg ctgggtagct
     4501 atgtagggaa gggataaacg ctgaaagcat ctaagtgtga aacccacctc aagatgagat
     4561 ttcccatgat tatatatcag taagagccct gagagatgat caggtagata ggttagaagt
     4621 ggaagtgtgg cgacacatgt agcggactaa tactaatagc tcgaggactt atccaaagta
     4681 actgagaata tgaaagcgaa cggttttctt aaattgaata gatattcaat tttgagtagg
     4741 tattactcag agttaagtga cgatagccta ggagatacac ctgtacccat gccgaacaca
     4801 gaagttaagc cctagaacgc cggaagtagt tgggggttgc cccctgtg
//
LOCUS       DAVFER010000077         4742 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1105170250
            SAMEA2167659-rid19724873.denovo.077, whole genome shotgun sequence.
ACCESSION   DAVFER010000077 DAVFER010000000
VERSION     DAVFER010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2167659
            Sequence Read Archive: ERR388902
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4742)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4742)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928716.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928716.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 04:07:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,118
            CDSs (total)                      :: 2,073
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 120
            CDSs (without protein)            :: 120
            Pseudo Genes (ambiguous residues) :: 0 of 120
            Pseudo Genes (frameshifted)       :: 67 of 120
            Pseudo Genes (incomplete)         :: 47 of 120
            Pseudo Genes (internal stop)      :: 34 of 120
            Pseudo Genes (multiple problems)  :: 23 of 120
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4742
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2167659-rid19724873.denovo.077"
                     /strain="1105170250"
                     /db_xref="taxon:1313"
     gene            complement(181..1932)
                     /locus_tag="VU534_002031"
     CDS             complement(181..1932)
                     /locus_tag="VU534_002031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU1514554.1"
                     /translation="MKRQTVNQTLKRLAVDLASHPFLLFLAFLGTIAQVGLSIYLPIL
                     IGQVIDQVLVAGSSPVFWQIFLQMLLVVIGNTLVQWANPLLYNRLIFSYTRDLRERII
                     HKLHRLPIAFVDRQGSGEMVSRVTTDIEQLAAGLTMIFNQFFIGVLMILVSILAMLQI
                     HLLMTLLVLLLTPLSMVISRFIAKKSYHLFQKQTETRGIQTQLIEESLSQQTIIQSFN
                     AQTEFIQRLREAHDNYSGYSQSAIFYSSTVNPSTRFVNALIYALLAGVGAYRIMMGSA
                     LTVGRLVTFLNYVQQYTKPFNDISSVLAELQSALACVERIYGVLDSPEVAETGKEVLT
                     TSDQVKGAISFKHVSFGYHPEKILIKDLSIDIPAGSKVAIVGPTGAGKSTLINLLMRF
                     YPISSGDILLDGQSIYDYTRVSLRQQFGMVLQETWLTQGTIHDNIAFGNPEASREQVI
                     AAAKAANADFFIQQLPQGYDTKLENAGESLSVGQAQLLTIARVFLAIPKILILDEATS
                     SIDTRTEVLVQDAFAKLMKGRTSFIIAHRLSTIQDADLILVLVDGDIVEYGNHQELMD
                     RKGKYYQMQKAAAFSSE"
     gene            complement(1934..3658)
                     /locus_tag="VU534_002032"
     CDS             complement(1934..3658)
                     /locus_tag="VU534_002032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU1514555.1"
                     /translation="MKHLLSYFKPYIKESILAPLFKLLEAVFELLVPMVIAGIVDQSL
                     PQGDQGHLWMQIGLLLIFAVIGVLVALIAQFYSAKAAVGSAKELTNDLYRHILSLPKD
                     SRDRLTTSSLVTRLTSDTYQIQTGINQFLRLFLRAPIIVFGAIFMAYRISAELTFWFL
                     VLVAILTIVIVGLSRLVNPFYSSLRKKTDQLVQETRQQLQGMRVIRAFGQEKRELQIF
                     QTLNQVYARLQEKTGFWSSLLTPLTYLIVNGTLLVIIWQGYISIQGGVLSQGALIALI
                     NYLLQILVELVKLAMLINSLNQSYISVKRIEEVFVEAPEDIHSELEQKQATRDKVLQV
                     QELTFTYPDAAQPSLRYISFDMTQGQILGIIGGTGSGKSSLVQLLLGLYPVDKGNIDL
                     YQNGRSPLNLEQWRSWIAYVPQKVELFKGTIRSNLTLGFNQEVSDQELWQALEIAQAK
                     DFVSEKEGLLDALVEAGGRNFSGGQKQRLSIARAVLRQAPFLILDDATSALDTITESK
                     LLKAIRENFPNTSLILISQRTSTLQMADQILLLEKGELLAVGKHDDLMKSSQVYCEIN
                     ASQHGKED"
     gene            complement(3716..4654)
                     /gene="msrB"
                     /locus_tag="VU534_002033"
     CDS             complement(3716..4654)
                     /gene="msrB"
                     /locus_tag="VU534_002033"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HEU1514556.1"
                     /translation="MAEIYLAGGCFWGLEEYFSRISGVLETSVGYANGQVETTNYQLL
                     KETDHAETVQVIYDEKEVSLREILLYYFRVIDPLSINQQGNDRGRQYRTGIYYQDEAD
                     LPAIYTVVQEQERMLGRKIAVEVEQLRHYILAEDYHQDYLRKNPSGYCHIDVTDADKP
                     LIDAANYEKPSQEVLKASLSEESYRVTQEAATEAPFTNAYDQTFEEGIYVDITTGEPL
                     FFAKDKFASGCGWPSFSRPISKELIHYYKDLSHGMERIEVRSRSGSAHLGHVFTDGPR
                     ELGGLRYCINSASLRFVAKDEMEKAGYGYLLPYLNK"
BASE COUNT         1406 a         1045 c          988 g         1303 t
ORIGIN      
        1 ctgacttcgt cagtcttatc tacaacctca aagctgtgct ttgagcaacc tacggctagc
       61 ttcctagttt gctctttgat tttcattgag tattacagtg aacaattttt ctagctattg
      121 taacaaaaaa gtcactcgaa ggcaactttt ttcgtccata aactttcaaa agagaatggc
      181 ttattcagaa ctaaaagccg cagctttttg catttggtaa tacttaccct ttctatccat
      241 gagttcttga tggttaccat attcaacaat atcaccatct actaagacaa gaattaaatc
      301 cgcatcctga atggttgaca aacggtgagc aatgatgaaa cttgtgcggc ccttcatgag
      361 ttttgcaaag gcatcctgta ccagcacttc tgtccgtgta tcaatggaag aagttgcctc
      421 gtctaagata agaatctttg gaatagccag aaagactcgg gctatggtca agagctgagc
      481 ttggccgaca gagagagatt ctccagcatt ttccaacttg gtatcgtatc cctgtggcaa
      541 ctgttggatg aaaaagtctg cattagctgc tttggcagca gcaattactt gctctcgact
      601 ggcttcagga ttgccaaagg caatattatc atgaatggtc ccttgtgtga gccaggtttc
      661 ttgaagcacc ataccaaact gctgtctcaa tgatactcgt gtataatcat aaatggattg
      721 cccatccagc aagatatctc ccgagctaat gggataaaaa cgcataagga gattgataag
      781 agttgatttt ccagcacctg tcggaccaac gatggctacc ttactaccag ctggaatatc
      841 gatagacaag tccttaatca aaattttttc aggatggtag ccaaaagaga catgtttaaa
      901 ggaaatagct cccttaactt ggtcactggt cgtcaagact tccttacctg tttcagccac
      961 ttcagggcta tctaagactc catagatacg ctctacgcaa gccagagcac tttgcaactc
     1021 agctagcact gaagaaatat cgttaaaggg cttggtgtat tgctgaacat agttcaaaaa
     1081 agtcactaaa cgaccgacgg tcaaggctga acccatcatg atacgataag ctcctactcc
     1141 agctaaaagg gcataaatga gtgcatttac aaagcgagtc gaaggattga ccgttgaaga
     1201 ataaaagatg gctgactgag aatagcctga gtagttgtca tgagcctcac gcaatctttg
     1261 gataaattct gtttgagcat tgaaggactg gattatagtc tgctgactaa gcgattcttc
     1321 aatcaactga gtctgaattc ccctcgtctc tgtttgcttc tggaagagat gataggattt
     1381 cttggcaata aagcgtgaaa tcaccatgga cagtggcgtc aacagcaaga ctaagagagt
     1441 catgaggaga tgaatttgga gcatggctag aatactgacc aaaatcatca aaacaccaat
     1501 gaaaaattgg ttaaaaatca tggtcaagcc agctgccaac tgttcgatgt ccgtggttac
     1561 acgactaacc atctctccac taccttgcct atctacaaag gcaatcggta aacgatggag
     1621 cttatggatg attcgctccc gtaaatctct ggtataagag aagattagac gattatagag
     1681 gagaggattg gcccattgta ccagagtatt tcctattacc accaagagca tctggagaaa
     1741 aatctgccaa aaaactggtg atgaaccagc cactaggact tggtcaatga cctgcccaat
     1801 cagaataggt aggtaaattg ataagccaac ttgggcaata gttcctagaa aggctaggaa
     1861 aaggaggaaa ggatggcttg ctaaatctac ggctaaacgt ttgagcgtct ggtttacagt
     1921 ttgtcgtttc attctagtcc tcctttccat gttgggatgc attgatttca caatagactt
     1981 ggctggattt catcaagtca tcgtgcttgc caacagctag caactcacct ttttccaaga
     2041 ggagaatctg gtccgccatc tgtaaagttg aggttcgttg agagatcaaa attaagctcg
     2101 tgtttggaaa attttctcta atagctttca agagcttgga ctctgtaatg gtatccagtg
     2161 ccgaggttgc atcatctagg atgagaaacg gagcctggcg caagactgct cgggcgatag
     2221 acaatctttg tttttgtcca cctgagaaat ttcgcccccc tgcctcaact agagcatcca
     2281 agagtccttc cttttcactg acaaaatcct tagcttgcgc aatctccaag gcctgccaga
     2341 gttcctggtc agatacttct tgattgaaac ctagagtcaa gttggaacga atggttcctt
     2401 taaagagttc gaccttttga ggtacatagg caatccaaga ccgccactgc tccaaattaa
     2461 gaggactacg tccattttga taaaggtcaa tgttcccctt gtctactgga taaagtccaa
     2521 gtaagagttg caccaagctt gatttaccag aaccagttcc cccgatgata cctagaattt
     2581 gtccttgagt catatcaaag gaaatgtatc tcagagaagg ctgggccgca tcaggatagg
     2641 taaaggtcaa ttcttggact tgtaaaacct tatctctggt agcttgcttt tgttctaact
     2701 ctgaatggat atcctctgga gcctcaacaa agacttcctc gattcgcttg actgagatat
     2761 aggactggtt gagggaattg atcaacatgg ctagcttgac caattccacc aaaatctgta
     2821 agaggtaatt gataagagca atgagagcac cttgactgag cactcctcct tgaattgaaa
     2881 tatagccttg ccagataata acgagaagag ttccattgac aatcagatag gtcagaggtg
     2941 ttaataaact agaccagaaa cctgtctttt cttgtaatct agcataaact tggttaaggg
     3001 tttgaaaaat ctgtaactct cgtttttctt gaccaaaagc acgaataacc cgcatccctt
     3061 gcaattgctg gcgcgtttcc tgaaccagtt ggtccgtttt ctttctgaga ctactgtaga
     3121 aaggattgac caatcgagat aaccctacaa tgacaatggt caaaatggca accaagacta
     3181 agaaccagaa agtcaactca gctgagattc gataagccat aaaaatggca ccaaaaacga
     3241 taatgggcgc tcgtaaaaag agacgcagga attgattgat accagtctga atctggtagg
     3301 tatccgaagt caagcgagtg accaaactag aagttgtcag acggtctctg ctgtccttgg
     3361 gcaaggaaag aatatgacga taaagatcgt ttgtcaattc cttagcagaa cctactgctg
     3421 cctttgctga gtaaaattga gctatcaagg ccactaaaac gccaattact gcaaagataa
     3481 ggagcaggcc aatctgcatc cagagatgac cttgatctcc ctgaggtaaa gattggtcaa
     3541 caatcccagc aatcaccatg ggaaccaaga gctcaaaaac agcttctaac agcttgaaca
     3601 agggggctaa aattgattcc ttgatgtagg gtttgaagta agataatagg tgtttcataa
     3661 atcccttcta ttcatattct agaaatgaag aaagtgggaa gccccactct ctgttttatt
     3721 tgtttaagta aggcaataga tagccatatc ctgctttttc catctcatcc ttggccacaa
     3781 agcgtaaaga agcagaattg atacagtaac ggaggccgcc taactcccgc ggtccatctg
     3841 tgaaaacatg acccaagtga gcactgcctg aacgagaacg aacttcaatt cgctccattc
     3901 catggctcag atccttgtaa taatgaatca actctttgga aatcggacgg ctaaaacttg
     3961 gccaaccaca acctgaagca aacttatcct tggcaaaaaa gagtggctca cctgtcgtaa
     4021 tatctacata aatcccctct tcaaaggttt ggtcataggc attggtaaat ggagcctctg
     4081 tagcagcttc ttgtgtgaca cgataagact cttcagatag actggccttc aacacctctt
     4141 gactaggctt ttcatagttt gctgcatcaa tcaatggctt atcagcatcg gtcacatcga
     4201 tatgacagta acctgaagga ttcttcctga gatagtcttg gtggtagtct tcagccagaa
     4261 tgtagtggcg taattgctcc acttctactg caatctttcg acccagcatg cgttcctgct
     4321 cctgcaccac tgtgtagata gctggcaaat ctgcttcatc ctgataataa atcccagttc
     4381 gatattggcg accacggtca ttcccttgtt gattgataga tagaggatcg ataactcgga
     4441 aataataaag taaaatctct ctgagtgaca cttccttctc atcgtaaatc acttggaccg
     4501 tttctgcatg gtctgtttcc ttgagcaact ggtaattggt cgtttcgact tgaccattag
     4561 cgtagccaac actggtttct agcactccag aaatgcgtga aaaatattcc tctaggcccc
     4621 aaaaacaacc acctgctaga taaatttctg ccatctttat ttctccttta tcacgttttt
     4681 aactaatact cttcgaaaat ctcttcaaac cacgtcagcg tcaccttacc gtaggtatgg
     4741 tt
//
LOCUS       DAVFER010000078         4245 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1105170250
            SAMEA2167659-rid19724873.denovo.078, whole genome shotgun sequence.
ACCESSION   DAVFER010000078 DAVFER010000000
VERSION     DAVFER010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2167659
            Sequence Read Archive: ERR388902
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4245)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4245)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928716.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928716.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 04:07:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,118
            CDSs (total)                      :: 2,073
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 120
            CDSs (without protein)            :: 120
            Pseudo Genes (ambiguous residues) :: 0 of 120
            Pseudo Genes (frameshifted)       :: 67 of 120
            Pseudo Genes (incomplete)         :: 47 of 120
            Pseudo Genes (internal stop)      :: 34 of 120
            Pseudo Genes (multiple problems)  :: 23 of 120
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4245
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2167659-rid19724873.denovo.078"
                     /strain="1105170250"
                     /db_xref="taxon:1313"
     gene            complement(<1..1288)
                     /locus_tag="VU534_002034"
     CDS             complement(<1..1288)
                     /locus_tag="VU534_002034"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HEU1514557.1"
                     /translation="MKLQKPKGTQDILPAESAKWQYVEGFAREIFKRYNYAEVRTPIF
                     EHYEVISRSVGDTTDIVTKEMYDFYDKGDRHITLRPEGTAPVVRSYVENKLFAPEVQK
                     PSKFYYMGPMFRYERPQAGRLRQFHQIGVECFGSSNPATDVETIAMAAHFLKEIGIQG
                     VKLHLNTLGNPESRAAYRQALIDYLTPLKETLSKDSQRRLEENPLRVLDSKEKEDKVA
                     VENAPSILDFLDEESQAHFDAVRQMLENLGVDYIIDTNMVRGLDYYNHTIFEFITEIE
                     GNDLTVCAGGRYDGLVAYFGGPETAGFGFGLGVERLLLILEKQGVTLPIENALDVYIA
                     VLGEGANIKALELVQALRQQGFKAERDYLNRKLKAQFKSADVFAAKTLITLGESEVES
                     GQVTVKNNQTREEVQVSLETISQNFSEIFEKLGFYTQ"
     gene            complement(1366..2613)
                     /locus_tag="VU534_002035"
     CDS             complement(1366..2613)
                     /locus_tag="VU534_002035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter"
                     /protein_id="HEU1514558.1"
                     /translation="MKLLFRNPAYRILTLSRFFNAFGVSIFNLVFIVYASTLSQASFA
                     VAMANIVMILPTLFTVFAGIRADYTRDKVKWMVYSGLFQAVLFFLAALVVQQASLFAF
                     SSLCLINVISDIISDFAGGLRMPLIKEKVAEDDLMEAYSFSQFITYISAIGGQAFGVW
                     LLALSVNNFSLVAGINACFFLVSATILFLGKSKLSLSMSSADGENLKNEKLSIKDQFL
                     TIYRNLRLVFLKSGQKNFGFMLFAVLLINSLGGALGGIYNIFFLSHSLLNFSYTEALF
                     INQFCVLVSVIISSLTGNDYFGKQSLPRLMMWETVGLSLVGLANLFNQVVLGLLFLFF
                     TLYVSGKVQPKISAMLMKNLAPEVLARTSNFLGLLFTLSIPVGTACFSLVAVWNIQLT
                     WMLFVGLSLLAIFLTILNLKNDI"
     gene            complement(2804..3654)
                     /gene="rgg"
                     /locus_tag="VU534_002036"
                     /pseudo
     CDS             complement(2804..3654)
                     /gene="rgg"
                     /locus_tag="VU534_002036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398326.1"
                     /note="Rgg, as the term is used in Streptococcus
                     pneumoniae, is the lone quorum-sensing system
                     transcriptional regulator related to proteins Rgg1, Rgg2,
                     Rgg3, and Rgg4 of Streptococcus pyogenes.; frameshifted;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system transcriptional regulator
                     Rgg"
     gene            3778..4119
                     /locus_tag="VU534_002037"
     CDS             3778..4119
                     /locus_tag="VU534_002037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003080443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HEU1514559.1"
                     /translation="MRDDIKINDRALALQDQIIEKLEKVFDTDVELDVYNLGLIYEIN
                     LDETGLCKIVMTFTDTACDCAESLPIEIVAGLKQIEGIKDIKVEVTWSPAWKITRISR
                     YGRIALGLPPR"
BASE COUNT         1352 a          891 c          828 g         1174 t
ORIGIN      
        1 attgagtata aaatcctagt ttttcaaaga tttctgagaa gttttggctg attgtctcaa
       61 gtgacacttg cacttcttct cgggtttggt tgttcttgac cgtcacttgt ccgctttcga
      121 cttcgctctc tcctagggtg atgagggtct tagccgcaaa gacatcggct gacttgaact
      181 gagcttttag tttacggttg aggtaatcac gctctgcttt gaaaccttgt tggcgaagag
      241 cctgtaccaa ttccaaggcc ttgatatttg ccccttcgcc caagactgcg atatagacat
      301 ctagggcgtt ttcgataggg agggtcacac cttgcttttc aaggatgaga agcaggcgct
      361 ctacaccaag tccaaaacca aatccagcag tttcagggcc tccaaagtaa gcaaccaaac
      421 catcgtagcg accacccgca cagacggtca ggtcattgcc ctcaatctct gtgataaact
      481 cgaaaatggt gtggttgtag tagtccagac cacgcaccat attggtatcg atgatgtaat
      541 ctactccaag attttccaac atctgacgca cagcatcaaa atgagcttgg ctttcttcat
      601 caagaaagtc caagatagac ggcgcattct ctactgccac cttgtcttct ttttccttag
      661 agtccaagac acgaagagga ttttcctcca agcgacgttg gctatcctta gacaaggtct
      721 ccttgagcgg tgtcaaatag tcaatcaagg cttggcggta ggctgcacgg ctctcaggat
      781 ttccaagagt gttgaggtgc aatttgacac cttgaatacc gatttccttc aaaaaatggg
      841 ctgccatagc gattgtttcc acatcggtag ctggattgct agagccaaaa cactcaacac
      901 caatctggtg gaattggcgc aagcgccctg cctgtggacg ctcataacgg aacataggtc
      961 ccatgtagta gaacttgctt ggcttttgca cttctggggc gaaaagttta ttttccacat
     1021 aggaacggac aacgggtgca gttccttctg gacggagggt aatatgacgg tcacccttgt
     1081 cataaaaatc gtacatttcc ttggttacga tatccgttgt atctccgaca gagcgactga
     1141 taacctcgta atgctcaaaa ataggcgtgc gcacttctgc atagttgtag cgtttgaaaa
     1201 tctcacgggc aaagccctca acgtactgcc acttagcaga ctcagcaggt aaaatatcct
     1261 gcgttccttt tggtttttgt aatttcatag ggaatcctct ttaaacttaa tagtcttatt
     1321 ttaccataaa tagagggatt aaaacagtaa gaaaaaaatt aggatttaga tatcattttt
     1381 gagattaaga attgtcaaaa aaatagctag caaggaaaga ccaacaaata gcatccaagt
     1441 caactgtata ttccatacgg ctactagtga aaaacaagct gttcccacag gtatggataa
     1501 ggtaaacaat agacctaaaa aattactagt acgagctaga acctctggag ctagattttt
     1561 catgagcatg gcactaatct ttggttgaac tttaccagac acatacagag taaagaagag
     1621 aaatagcaaa ccaagcacga cttgattgaa taaattagcc aaaccaacta gactaagtcc
     1681 tacggtctcc cacatcatca atctaggcaa ggactgcttc ccaaaataat cattgcccgt
     1741 aaggctactg atgatgactg atactaaaac acagaattga ttgataaata gtgcctctgt
     1801 ataagaaaaa ttcaagagag aatggctcaa aaagaagata ttataaattc cacccaaagc
     1861 gccacccaag gaattaataa gcaagacagc aaagagcata aaaccaaagt ttttctgtcc
     1921 acttttaaga aaaacgagac gtaaatttcg gtaaattgtt aggaactggt ctttgataga
     1981 aagcttctca ttttttaagt tttcaccatc agcagatgac attgacaggc tcaatttgct
     2041 ttttcctaaa aagaggatag tggctgatac taggaaaaag caggcattga ttcccgcaac
     2101 gagagaaaaa ttgttgaccg atagagctaa gagccagact ccgaaagctt gaccaccaat
     2161 agctgaaata taggtgatga actgtgaaaa agaataagcc tccatcagat catcttcagc
     2221 tactttttcc ttaataagag gcatacgcag gccacctgca aaatcactga tgatatcact
     2281 aatgacattg atcaaacaca ggctagaaaa ggcaaagaga ctagcttgct gaacaactag
     2341 ggctgctaga aaaaatagaa ccgcctgaaa caaaccgcta tagaccatcc atttgacctt
     2401 gtccctcgtg taatctgccc gaatccctgc aaaaactgta aagagggtcg gaagaatcat
     2461 gacaatattc gccatagcaa cagcaaaaga tgcttgtgac aaggtcgatg catagacgat
     2521 aaagaccagg ttgaaaatcg aaacaccaaa agcattgaag aagcgtgata aagtcaaaat
     2581 tctataagct ggatttctaa acaatagttt catagataat ctccctcctt gttctaagtt
     2641 ctacatcaag aatagcttta gtatagcact tatgaatttg cgaaacgatt cttttgaata
     2701 tatgcaacaa acaaaatgag caaaaaaacg atagaacttt tgtaatgacc tgagagaggg
     2761 caacagttct atcgcttcaa attttttctt ggtttgcaga tattcaagaa tcgggagttt
     2821 ttctatagta ttcggcagat ttattacagc caagcatctc aaaaatacgg acagcatcct
     2881 ccatcttttt ctggccttcc ttgactctac cttgcttgct atcaaggaga ccttctgccc
     2941 acagataaac aattcggaaa taggtctcat tttccttgta gaaatgctct tcgataacac
     3001 gtttaaaata ataggcattg gtaaattctt cacactcaat actagctaaa aagccattca
     3061 atagtatagt atgaaaaagg tttcgattgc cagacatttc cattagaaaa tcagatttac
     3121 gtaccatttc tcgtacatat ctagtaaaaa gagaaacaga taaaaatgga gaactgactg
     3181 aaaataaatt gagttcatag attccccaga tctcggtaga aaacaaataa tcatgaagga
     3241 cttttccttc ctctgctgtt aagtctaccc tttcatctat gctcttcata taagacttga
     3301 taataatggc atttagaata tgtttctgtt tgttgtgaga atgggcatgc ttttatactc
     3361 cctgcgatat aagtcctcaa gaggtgctat attctttggt tccaagacat ctgtaatttc
     3421 ttttctcaac tcagaatctg tatcatactg gaaacctctt gccagaaaga ggatctcctc
     3481 cacactggca gatatatttt ccagagcaaa tagaaacttt tccaccgaaa gctcactctg
     3541 acctgtttca aaacgggaca acatagacgg cgaaaattgt cctccggttg cttgtctcag
     3601 tgagatattt cttgactctc gtaattgtct aaagactttt ccaatctgct ccatagactt
     3661 ccccttgatt ccgtattttc ttcattttat catatttttc agaaaattca tcaaaaactt
     3721 gccaaattgt cagaattatg agaaaataga ggatatttat cacgtggagg gactgctatg
     3781 agagacgata tcaaaatcaa tgaccgtgct ttggccttgc aagaccaaat tatcgaaaaa
     3841 ctagagaaag tttttgatac agatgtggaa ttggatgttt acaatctagg tctgatttat
     3901 gaaatcaatc tggatgaaac ggggctctgc aagattgtca tgaccttcac cgatactgcc
     3961 tgtgattgcg ccgaaagcct gcctattgaa atcgtggcag gtctgaaaca aatcgagggt
     4021 atcaaagata tcaaggttga agttacctgg tcgcctgctt ggaaaatcac acgaatcagt
     4081 cgctatggcc gtattgccct tggactacca cctcgttaag cagaccaatc acttttaaag
     4141 atgaaaaaag caagccgaaa atggcttgct ttttgatact caatgaaaat caaagggcaa
     4201 actagaaaac tagccgcagg ttgctcaaaa cactgttttg aagtt
//
LOCUS       DAVFER010000079         3931 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1105170250
            SAMEA2167659-rid19724873.denovo.079, whole genome shotgun sequence.
ACCESSION   DAVFER010000079 DAVFER010000000
VERSION     DAVFER010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2167659
            Sequence Read Archive: ERR388902
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3931)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3931)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928716.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928716.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 04:07:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,118
            CDSs (total)                      :: 2,073
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 120
            CDSs (without protein)            :: 120
            Pseudo Genes (ambiguous residues) :: 0 of 120
            Pseudo Genes (frameshifted)       :: 67 of 120
            Pseudo Genes (incomplete)         :: 47 of 120
            Pseudo Genes (internal stop)      :: 34 of 120
            Pseudo Genes (multiple problems)  :: 23 of 120
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3931
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2167659-rid19724873.denovo.079"
                     /strain="1105170250"
                     /db_xref="taxon:1313"
     gene            160..402
                     /locus_tag="VU534_002038"
                     /pseudo
     CDS             160..402
                     /locus_tag="VU534_002038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800706.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Rgg/GadR/MutR family transcriptional regulator"
     gene            complement(756..1289)
                     /locus_tag="VU534_002039"
     CDS             complement(756..1289)
                     /locus_tag="VU534_002039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000775318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF402 domain-containing protein"
                     /protein_id="HEU1514560.1"
                     /translation="MKLPKEGDFITIQSYKHDGSLHRTWRDTMVLKTTENAIIGVNDH
                     TLVTESDGRRWVTREPAIVYFHKKYWFNIIAMIRDNGTSYYCNMASPYYLDEEALKYI
                     DYDLDVKIFTDGEKRLLDVEEYERHKRKMNYSDDLDYILKEHVKILVDWINNGRGPFS
                     EAYVNIWYKRYVELKNR"
     gene            complement(1378..2154)
                     /gene="recX"
                     /locus_tag="VU534_002040"
     CDS             complement(1378..2154)
                     /gene="recX"
                     /locus_tag="VU534_002040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000705102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HEU1514561.1"
                     /translation="MKITKLEKKKRLYLMELDNGDKCYITEDTIVRFMLSRDKVISEE
                     ELKEIQDFAQFSYGKNLALYHLSFKARTEKEVREYLKKYDINENIVSQVIANLKEEKW
                     INDSQYAYAIINANQLSGDKGPYVLTQKLAQKGISKSTIEEILNDFDFSEVAQRVANK
                     LLKKYEGKLPARALQDKIIQNLTNKGFSYFDAKIAFDELDSQVDEETTQELIFKELDK
                     QYTKYARKYEGYELKQRLTQVLARKGYDFSDIASALREYL"
     gene            2192..3547
                     /gene="rlmD"
                     /locus_tag="VU534_002041"
     CDS             2192..3547
                     /gene="rlmD"
                     /locus_tag="VU534_002041"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HEU1514562.1"
                     /translation="MNLKVKQKIPLKIKRMGINGEGIGFYQKTLVFVPGALKGEDIYC
                     QITSIRRNFVEAKLLKVNKKSKFRIVPSCTIYNECGGCQIMHLHYDKQLEFKTDLLHQ
                     ALKKFAPAGYENYEIRPTIGMQEPKYYRAKLQFQTRKFKNQVKAGLYAQNSHYLVELK
                     DCLVQDKETQVIANRLAELLTYHQIPITDERKVLGVRTIMVRRARKTGQVQIIIVTNR
                     QLNLTQLVKELVKDFPEVVTVAVNTNTAKTSEIYGEKTEIIWGQESIQEGVLNYEFSL
                     SPRAFYQLNPEQTEVLYSEAVKALDVDKEDHLIDAYCGVGTIGFAFAKKVKTLRGMDI
                     IPEAIEDAKRNAKRMGFDNTHYEAGTAEEIIPRWYKEGYRADALIVDPPRTGLDDKLL
                     DTILTYVPEKMVYISCNVSTLARDLVRLVEVYDLHYIQSVDMFPHTARTEAVVKLIKK
                     V"
     gene            3609..3680
                     /locus_tag="VU534_002042"
     tRNA            3609..3680
                     /locus_tag="VU534_002042"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:3642..3644,aa:Glu,seq:ttc)
BASE COUNT         1307 a          660 c          704 g         1260 t
ORIGIN      
        1 tcgagcagtt ttgtgataaa atgtaattgt tccatatgaa tctttctaat gagttgtttt
       61 gtcgcttttc attataggtc atatgggact ttttttctac aacaaaatag gctccataat
      121 atctataagg gatttaccca ctacaaatat tatagagccg aaaattcaca tctaatatat
      181 gcagactact ttgaaatgaa attaaaaaaa ttattaaagg atgacacaaa agtttttgaa
      241 aaatctacat tcaaatttgt agaaggatat aaaatatacc tgacagaatc taaagaatct
      301 ggaattaaac aaatggacaa tgtcataaaa tattttgagt ttattgaatc taaaagtatt
      361 gctttatatt ttcaaaaacg attaaatgag ctgatagatt aaatagcatt ttctctgttg
      421 agatattgtt tttaaaatat tgtactaaat gattgatgct atgtggaaat acaaaaaaat
      481 gtttttgata cgaagttgac ctgtattttt tatactaatc attttcgtat tttttgtatt
      541 aaacgatata agtttgttgt aaacttacaa ggaataaaga cattaaaaaa taacagtata
      601 tctatttgtt ttatatattt tacgaattct gcataaatct ctttctagta atgtgttgta
      661 actctgctat aatagattta ttcctttttg tgtttacaca atttatttta tactaccaaa
      721 aaaggtcagg attttgttcc tgacctttga caactttacc gattctttag ttctacatag
      781 cgcttgtacc aaatgtttac ataggcttct gagaaaggac cacgtccatt gttaatccaa
      841 tcaacaagaa ttttgacatg ttcttttaaa atatagtcca agtcatcaga ataattcatt
      901 ttgcgtttgt gacgctcgta ctcttcaacg tccaagagac gtttttcccc atctgtaaaa
      961 attttaacat ccaaatcgta atcaatatac ttcagtgctt cttcatccag atagtagggg
     1021 ctagccatat tgcaatagta agaagttcca ttatcacgaa tcatggcaat gatattaaac
     1081 caatatttct tgtgaaagta aacaatagcc ggttctcgag tgacccaacg acgaccatca
     1141 ctttcggtaa caagtgtatg atcgttgaca ccaataatgg cgttttctgt tgtttttagt
     1201 accatggtgt cccgccaagt tcggtggaga ctcccatcat gcttataact ttgaattgta
     1261 ataaagtcgc cttcttttgg aagcttcata actaaccaac tttctacaat ttataagttt
     1321 atcatttact attgtaccat aaaattaccc aaaatctgtg aatttcactt ggaaatatta
     1381 aagatattct ctaagagcgc ttgctatatc cgaaaaatcg tagccctttc gtgctaaaac
     1441 ttgagttaaa cgctgcttca gttcgtatcc ttcatacttt cgggcatact tagtatattg
     1501 cttatcaagt tccttgaaga tgagttcctg agtcgtttct tcatcaactt gactatccaa
     1561 ttcgtcaaag gcaattttag catcaaaata agagaagccc ttgttagtca agttctggat
     1621 aatcttatct tgcagggcac gagctggaag ttttccctca tattttttca atagtttatt
     1681 ggctacacgt tgagcaactt ccgaaaaatc aaaatcattc aagatttctt ctatagtaga
     1741 ttttgaaatt cctttttgtg ctaatttctg agtcagtaca taaggtccct tgtctcctga
     1801 aagttgattg gcattgatga tagcataagc gtactggcta tcattaatcc acttctcttc
     1861 tttaagatta gcaatgactt gagaaacgat gttttcatta atatcatatt ttttcagata
     1921 ttctctgacc tctttttcag tacgtgcttt aaaggataag tggtagaggg ccagattctt
     1981 accataagaa aattgagcaa agtcttgaat ctctttcaat tcctcttcgc ttatcacctt
     2041 atctctcgat aacataaaac gaacaattgt gtcttcggtg atatagcatt tgtcgccatt
     2101 atcaagctcc atcagataga gtcttttttt cttttcaagt tttgtgattt tcatagctct
     2161 attataactc aaaatgtgat aagatagggg tatgaatctg aaagtgaaac aaaaaatacc
     2221 attaaaaatc aagcgcatgg gaattaacgg tgagggaatc ggcttttacc aaaaaacatt
     2281 agtctttgta ccaggagctc tcaaaggcga agatatctat tgtcagatta cttctattag
     2341 acgcaacttt gttgaagcaa aattactgaa ggtcaacaag aagtctaaat ttcgaattgt
     2401 gccatcttgt actatttata atgaatgcgg aggctgccaa atcatgcacc tgcattatga
     2461 taagcagctg gagttcaaga cggacttact tcatcaagcg ctgaaaaaat ttgctcctgc
     2521 aggatatgaa aattatgaaa ttcgtccaac tattggaatg caggaaccaa aatattacag
     2581 agctaagtta caatttcaga ctcgaaaatt taaaaatcag gtcaaggcgg gcttatatgc
     2641 acaaaactct cactatttag tagagttgaa agactgcctg gtacaagata aggaaaccca
     2701 agtgattgct aatcgcttag cagaattact tacttatcac cagattccaa tcacggatga
     2761 gagaaaagtt ctaggtgtcc gtactattat ggtccgacgc gcgagaaaga ccggacaggt
     2821 tcagattatt attgttacaa accgccagct taatttaact caattggtaa aagagttggt
     2881 taaagatttc ccagaagttg tgacagtagc tgttaataca aatacagcta aaaccagtga
     2941 gatatatggt gaaaagacag agattatctg ggggcaagag agtattcaag aaggtgtact
     3001 caattatgaa ttttcactat cccctcgagc tttttatcaa ctaaatcctg agcaaacaga
     3061 agtcctctat agcgaagcag taaaagcgct ggatgttgat aaagaagacc atttgattga
     3121 cgcttattgt ggagttggaa cgattggatt tgcctttgca aagaaagtaa aaacactcag
     3181 aggtatggat attattccag aagctattga agatgccaag cgaaatgcta aaagaatggg
     3241 atttgacaat actcattatg aagctggaac ggcagaagag attattcctc gttggtacaa
     3301 ggaaggctac cgagcagatg ctttgattgt tgacccacca cgtacaggtc tggatgataa
     3361 gttattagat actattctta cttatgtacc agaaaaaatg gtttatattt cttgtaatgt
     3421 ttcgaccttg gctcgtgatt tggtacgctt agtagaagtc tatgatcttc attatatcca
     3481 gtcggtcgat atgttcccac atacagctcg aactgaagct gttgtaaaat taataaaaaa
     3541 agtttaaaaa agtagttgac aaagtttgaa aagactgtat aatagtaaga gttgaaaata
     3601 acaactcagg tccgttggtc aaggggttaa gacaccgcct tttcacggcg gtaacacggg
     3661 ttcgaatccc gtacggacta tggtatgttg cggttggaac acttgatgaa aaaaagttta
     3721 aaaaaactta aaaatcttca aaaaaagtgt tgacaagtga aagtggctgt gatatactaa
     3781 tatagttgtc gcttgagaga agcaagtgac aaagaccttt gaaaactgaa caagacgaac
     3841 caatgtgcag ggcgctacaa cataagttgt agtactgaac aatgaaaaaa acaataaatc
     3901 tgtcagtgac agaaatgagt gagaactcaa a
//
LOCUS       DAVFER010000080         3200 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1105170250
            SAMEA2167659-rid19724873.denovo.080, whole genome shotgun sequence.
ACCESSION   DAVFER010000080 DAVFER010000000
VERSION     DAVFER010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2167659
            Sequence Read Archive: ERR388902
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3200)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3200)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928716.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928716.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 04:07:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,118
            CDSs (total)                      :: 2,073
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 120
            CDSs (without protein)            :: 120
            Pseudo Genes (ambiguous residues) :: 0 of 120
            Pseudo Genes (frameshifted)       :: 67 of 120
            Pseudo Genes (incomplete)         :: 47 of 120
            Pseudo Genes (internal stop)      :: 34 of 120
            Pseudo Genes (multiple problems)  :: 23 of 120
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3200
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2167659-rid19724873.denovo.080"
                     /strain="1105170250"
                     /db_xref="taxon:1313"
     gene            complement(<1..257)
                     /locus_tag="VU534_002043"
     CDS             complement(<1..257)
                     /locus_tag="VU534_002043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU1514563.1"
                     /translation="MEQLHFITKLLDIKDPNIKILDIINMDTHKEIIAKLDYEAPSCP
                     DCGSLMKKYDFQKPSKIPYLETTGMPTRILLRKRRFKCYHCS"
     gene            complement(412..1122)
                     /gene="treR"
                     /locus_tag="VU534_002044"
     CDS             complement(412..1122)
                     /gene="treR"
                     /locus_tag="VU534_002044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose operon repressor"
                     /protein_id="HEU1514564.1"
                     /translation="MKKYQQLFKQIQETIQNETYAVGDFLPSEHDLMEQYQVSRDTVR
                     KALSLLQEEGLIKKIRGQGSQVVKEETVNFPVSNLTSYQELVKELGLRSKTNVVSLDK
                     IIIDKKSSLITGFPEFRMVWKVVRQRVVDDLVSVLDTDYLDMELIPNLTRQIAEQSIY
                     SYIENGLKLLIDYAQKEITIDHSSDRDKILMDIGKDPYVVSIKSKVYLQDGRQFQFTE
                     SRHKLEKFRFVDFAKRKK"
     gene            1307..>3200
                     /gene="treP"
                     /locus_tag="VU534_002045"
     CDS             1307..>3200
                     /gene="treP"
                     /locus_tag="VU534_002045"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system trehalose-specific EIIBC component"
                     /protein_id="HEU1514565.1"
                     /translation="MGKFEQEAKDLLQAIGGKENVTAVTHCATRMRFVLGDDKKANVK
                     AIESIPAVKGTFTNAGQFQVIIGNDVPIFYNDFTAVSGIEGVSKEAAKSAAKSNQNVV
                     QGVMTTLAEIFTPIIPALIVGGLILGFRNVLEGVHWSMLDGKTITESSQFWAGVNHFL
                     WLPGEAIFQFLPVGITWSVSRKMGTSQILGIVLGICLVSPQLLNAYAVASTPAADIAA
                     NWVWNFGYFTVNRIGYQAQVIPALLAGLSLSYLEIFWHKHIPEVISMIFVPFLSLIPA
                     LILAHTVLGPIGWTIGQGLSSVVLAGLTGPVKWLFGAIFGALYAPFVITGLHHMTNAI
                     DTQLIADAGGTALWPMIALSNIAQGSAVFAYYFMHRHDEREAQVSLPATISAYLGVTE
                     PALFGVNVKYIYPFVAGMTGSALAGMLSVTFNVTAASIGIGGLPGILSIQPQYMLPFA
                     GTMLVAIVVPMLLTFFFRKAGLFTKTEGDTNLQAEFVAQEEAEFVNHEPVELTSVEII
                     SPLTGQVKELSQATDPIFASGVMGQGLVIEPSQGELTSPVNGTVTVLFPTKHAIGIVS
                     DEGVELLIHIGMDTVGLDGKGFESLVVQGDHVTVGQQLIRFDMDVIKAAGLVTETPVI
                     ITNQDAY"
BASE COUNT          825 a          642 c          707 g         1026 t
ORIGIN      
        1 gaacaatgat agcacttgaa acgacgcttt ctaaggagaa ttctagtagg cataccagtt
       61 gtttcgaggt aagggatctt agacggtttt tgaaagtcat atttcttcat tagacttcca
      121 caatcagggc aagatggagc ctcataatcc agcttagcga taatttcttt gtgggtatcc
      181 atattgatga tgtctagaat cttgatgttt gggtctttaa tatcgagcag ttttgtgata
      241 aaatgtaatt gttccatatg aatctttcta atgagttgtt ttgtcgcttt tcattatagg
      301 tcatatggga ctttttttct acacaaaata ggctccataa tatccatagg ggggttaccc
      361 actacaaata ttatagagcc gaaaaaggct gagatctggt gtctcagtct tttatttctt
      421 gcgttttgca aaatctacaa atctaaattt ctctaactta tggcgacttt cggtaaactg
      481 aaattggcgt ccgtcttgga gatagacttt tgatttaatc gaaacgacat aagggtcttt
      541 gccaatgtcc atgagaatct tgtctcggtc gcttgagtgg tcaatggtga tttccttctg
      601 agcataatca ataaggagtt tgaggccatt ttctatataa gaatagatag actgctcagc
      661 aatttggcga gtgagatttg ggatgagttc catatccaga tagtccgtat ccagaacgga
      721 taccagatca tccaccacac gctggcggac caccttccaa accatccgaa actctgggaa
      781 accggttatc agtgaggatt ttttatcaat aataatcttg tccagactga ccacgttggt
      841 tttagagcgc agtccaagtt ctttaactag ttcttggtag ctggttaggt tggatacagg
      901 gaaattgacg gtttcttctt tgacgacttg agaaccttgc cctcttatct ttttgatcaa
      961 tccttcctct tggaggagag acagggcctt tcggacggta tcacgactca cttgatattg
     1021 ctccataagg tcgtgctcgc taggaaggaa atctccgaca gcgtaagtct cgttttgaat
     1081 ggtttcttgg atttgcttaa ataattgttg gtatttcttc attttgcctg cttaaatagg
     1141 tttttagtct agtttaatga acacctgtat ctattttacc atacaagtgc tagaaaattt
     1201 acaaaaaaac acccttttta taccaaacaa gttgcagaca agtttggtat cgtttacaat
     1261 atacttatca aatcaaactt gctttgacaa gtataaggag aatcaaatgg gaaaatttga
     1321 acaagaagcc aaagatctgc ttcaggcaat cggaggcaaa gaaaatgtga ctgccgtaac
     1381 tcactgtgcg acacggatgc ggtttgtttt aggagatgat aagaaggcta atgttaaagc
     1441 tatcgagtca attccagctg ttaaaggaac ctttacaaat gcaggtcaat ttcaggtaat
     1501 cattggaaat gacgtgccca tcttttataa tgattttaca gccgtttcag gtattgaggg
     1561 tgtttccaaa gaagcagcca agtctgcagc taagagtaat caaaacgtgg tccaaggtgt
     1621 tatgaccact ctggcggaga tttttactcc gattattcca gccttgatag tcggaggatt
     1681 gatcctcggt ttccgtaatg tcttggaagg tgtccattgg tcgatgttgg atggcaagac
     1741 catcacagaa tcctctcagt tttgggcagg tgtcaatcac ttcctctggt tgcctggtga
     1801 agctatcttc cagttcttac cagtagggat tacttggtct gtttctcgta agatgggaac
     1861 cagccaaatt ttgggaattg ttctcggaat ctgtttggta tcgcctcagt tgctcaatgc
     1921 ctatgcggtt gcttcaacgc cagcagctga tatcgcggca aactgggttt ggaattttgg
     1981 ctattttact gttaatcgta tcggttacca agcccaagtt atcccagcct tgcttgcagg
     2041 tttgagtctg tcttatcttg aaatcttctg gcacaagcat atcccagaag tcatttctat
     2101 gatttttgta cctttcttgt cattgattcc agccttgatt ttggctcata ctgttttggg
     2161 accaatcggt tggacaattg gacaaggact ttcatcagtt gtcttggcag gtttaactgg
     2221 tccagttaaa tggctcttcg gtgcaatttt tggcgccctc tacgctccat ttgtcatcac
     2281 aggtctgcac catatgacca atgccattga tacacaattg attgcggatg ctggtggcac
     2341 tgccctatgg ccaatgattg ctctttctaa tattgctcaa ggctcagccg tgtttgccta
     2401 ttatttcatg catcgccatg atgagcgtga ggctcaggtt tcacttcctg caaccatttc
     2461 agcctatctc ggtgttacag aaccagctct ttttggggtt aacgtaaaat atatttatcc
     2521 atttgttgct gggatgactg gttcagccct tgcaggcatg ttatccgtta cttttaatgt
     2581 aactgcggct tctattggta tcggtggttt gccaggtatt ctctctattc aacctcaata
     2641 catgctgcca tttgcaggaa ctatgctagt tgcgattgtt gttccaatgc tcttgacttt
     2701 cttcttccgc aaggctggtc tctttacaaa aacagagggc gatacgaact tgcaggcaga
     2761 attcgttgct caagaagaag cagaatttgt gaaccatgaa ccagtagaac ttacttcggt
     2821 agaaattatc agcccactaa ctggccaagt gaaagaattg agtcaagcga cggatcctat
     2881 ttttgcatca ggtgtcatgg ggcaaggtct agtcattgaa ccaagccaag gtgagttgac
     2941 ctctccagtt aatgggacag tgacggttct tttccctacc aagcatgcca tcggcattgt
     3001 ctctgacgag ggagttgaat tgctcatcca catcggtatg gatacagtag gtcttgatgg
     3061 caaaggtttt gaaagtcttg tagtccaagg agatcacgtt acagttggtc agcaactgat
     3121 tcgttttgat atggatgtca ttaaggctgc aggtctggtg acagaaactc ctgttatcat
     3181 caccaaccaa gatgcttata
//
LOCUS       DAVFER010000081         3194 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1105170250
            SAMEA2167659-rid19724873.denovo.081, whole genome shotgun sequence.
ACCESSION   DAVFER010000081 DAVFER010000000
VERSION     DAVFER010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2167659
            Sequence Read Archive: ERR388902
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3194)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3194)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928716.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928716.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 04:07:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,118
            CDSs (total)                      :: 2,073
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 120
            CDSs (without protein)            :: 120
            Pseudo Genes (ambiguous residues) :: 0 of 120
            Pseudo Genes (frameshifted)       :: 67 of 120
            Pseudo Genes (incomplete)         :: 47 of 120
            Pseudo Genes (internal stop)      :: 34 of 120
            Pseudo Genes (multiple problems)  :: 23 of 120
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3194
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2167659-rid19724873.denovo.081"
                     /strain="1105170250"
                     /db_xref="taxon:1313"
     gene            40..491
                     /locus_tag="VU534_002046"
                     /pseudo
     CDS             40..491
                     /locus_tag="VU534_002046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000013080.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
     gene            656..955
                     /locus_tag="VU534_002047"
     CDS             656..955
                     /locus_tag="VU534_002047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000767202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HEU1514566.1"
                     /translation="MKLINTTNSHSQLVKSQLESTDATLVEVYSAGNTDVIFTQAPLH
                     YEILISNKHRAIREPEIETIQEFFLKRKIDKASVDEANIKTLYSEKLIGISIPIK"
     gene            complement(1064..2401)
                     /locus_tag="VU534_002048"
                     /pseudo
     CDS             complement(1064..2401)
                     /locus_tag="VU534_002048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            2642..2929
                     /gene="tnpB"
                     /locus_tag="VU534_002049"
     CDS             2642..2929
                     /gene="tnpB"
                     /locus_tag="VU534_002049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HEU1514567.1"
                     /translation="MIIQLSDLGQVHLVCGKTDMRQGIDSLAYVVKTHFELDSFSGQV
                     FLFCGGRKDRFKALYWDGQGFWLLYKRFENGKLTWLSTEKDVKALAPEQVD"
BASE COUNT          975 a          618 c          532 g         1069 t
ORIGIN      
        1 actataataa taacgatact agataatgag gaaaatgcaa tggcaaaccc aactttcgga
       61 gaaaaaaagt gaatacagac tatattgctc gctatggcgt atatgcagtt atccctaatc
      121 ctgaacaaaa acaaattgtt cttgttcaag aaccaaatgg tgcttggttc ctaccatgtg
      181 gagaaattga agcaggtgaa aatcatcagg aagccctaaa gcatgagttg attgaagagc
      241 ttggtttcac agcagaaatt ggtacctatt acggacaagc tgacgaatat ttctattctc
      301 gtcatcgtga tacctactac tacaatcctg cctacctcta tgaagcaact cctttcaaag
      361 aagtacaaaa gccactagaa aactttaatc atattgcctg gttccctatt gacgaggcta
      421 tcaaaaacct taaacgtggt agccataaat gggccattga atcttggaaa aaacagcata
      481 agattggcta atactcttcg aaaataaaat tcaaaccacg tcagcgtcgc cttaccgtac
      541 tcaagtatag cctgcggcta gcttcctagt ttgctctttg attttcattg agtataaatc
      601 aagcgacttt attcaaaaag tgctataata gaattagaaa atcggaggaa atattatgaa
      661 gcttatcaat acgacaaact cacactcgca acttgtaaaa agtcagctag aaagtaccga
      721 tgcaaccctt gttgaggttt attctgcagg gaatacagat gttattttta cccaagctcc
      781 gcttcactat gaaatcctca tctcaaacaa acaccgtgct attcgtgagc ctgaaatcga
      841 aaccattcaa gaatttttct tgaaacgtaa aattgataag gcctctgttg atgaagccaa
      901 tatcaagaca ctctactcag agaaattaat tggaatttca atcccaatca agtaagaaaa
      961 ttgagtaaaa actcgatttg agagaaagtc caataagtct ttcaataata aaacgcatag
     1021 tagcaagagt tttgtactga ccccaaaaag ttagacaatt aatttatcca aaggatttag
     1081 ttctgtactg cacaggacta agtcctttta gttttacctt aattcgtttg ttgttgtagt
     1141 aatcaatata gtctataatg gcttgttcca attggttaag tgatttaaat gttttctcat
     1201 agccataaaa catttcggat tttaaaatgc caaagaaaga ttccatcata ccgttgtctt
     1261 ggctgttgcc cttgcgtgac atagatgctt gaattccctt actctctagg aaccgatgat
     1321 aagaatcgtg ttgatattgc cagccttggt cactatggag aatcgtattc tcgtagtgct
     1381 tctctttgaa tgcctgttct aacattgttt gtacttgttc taagttgggt gaagtcgaaa
     1441 gattaaaagc aataatttcg ctattaaagc catctaaaac tggtgataag taaagctttt
     1501 gagtacttgc tggaatggca aattctgtca catctgtgta gcacttttcc attgttttag
     1561 agccttcaaa ttggccttga atgagattct ctgccttctt accaacgtct cctttatttt
     1621 cgtttctgtc gcattttagc ttgtaaattg agtactttca tcaagccttg aactctttta
     1681 tgatttacca gataaccacg atttcttagt tctaaataaa tccgacgata accataattt
     1741 cccttgtgtt cgataaaaat ggattgaatt tcagctttaa gctcttggtc cttatctggt
     1801 ttgtctagct gtttcaagtg atagtagtag gtccaacgag ctagtttaat ggcttttaga
     1861 agaagatcta acgaaaactc agtcattaat tcttgaacaa tttctgtctt tcttctttct
     1921 ctttttcctc cttccatcgg agttctctta acttttttag gatagcattc tccgctctca
     1981 ggtactcatt ttctgcttga agacgttcta attctgttct ctcttcaggt ctcttttttg
     2041 gcttacgtcc cattttaggt actctccctc ttgttttctc aacaatagta tacccgtttt
     2101 ttctgtattg tgctagccag ttaagaagta tcgtacgact tgggagaccg tattcaagag
     2161 aaactctatc tttagttcag ccttcatgta agactttatt aatcatttct tgttttaaat
     2221 caggaaaata gtaacgattt tttccttttt tgacgaactc tattccgtaa cgatcaatca
     2281 atttaatcat atacctaaga ttagaattat ttatcccaaa tttatttgaa agcttctcta
     2341 agctatatcc ttgttttcta agttcataga tctgaacttt atcatcataa cttaatttca
     2401 taacaaaaac accccaaaag ttagattttt tctgtctaac ttttggggca gtacatttca
     2461 atacctgata ctatgcgttt ttatcatttt gaaatctact gctaatcaat gaagaagcaa
     2521 agatcaaact aggcagctag ttacaagtta cgtaagcgcg tcataacaag gtatctatcc
     2581 taattcccca acttccagta tactagataa aaaataatta tcggaggaaa ggtattgtac
     2641 tatgataatt caactaagtg atttaggtca agttcacctt gtttgtggca agacagatat
     2701 gaggcaggga atagactcat tagcctatgt agttaaaacc cactttgaat tggattcttt
     2761 ctccggtcaa gtctttctct tttgtggtgg acgtaaagac cgctttaaag ccctttactg
     2821 ggatggtcaa ggattttggc tactatataa acgctttgag aacggaaaac tgacttggct
     2881 aagtacagaa aaagatgtca aagctctcgc acctgaacaa gtagactagc ttatgaaggg
     2941 cttttctatc actccaaaaa tatagtagat tgaaactaga atagtacacc tctgcttcta
     3001 aaacattgtt agaaatcgat ttgactgtcc tgatcgattt gtcctgttct tatttcattt
     3061 tactataaat ccatcagaaa gtcgtgattt ctattgaaat gaggactttc tttttatact
     3121 catctgtttt caaaaagcat tctagtccat ctccgattaa cgatggactt tatcacctcc
     3181 ttctccaatc cttg
//
LOCUS       DAVFER010000082         3016 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1105170250
            SAMEA2167659-rid19724873.denovo.082, whole genome shotgun sequence.
ACCESSION   DAVFER010000082 DAVFER010000000
VERSION     DAVFER010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2167659
            Sequence Read Archive: ERR388902
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3016)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3016)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928716.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928716.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 04:07:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,118
            CDSs (total)                      :: 2,073
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 120
            CDSs (without protein)            :: 120
            Pseudo Genes (ambiguous residues) :: 0 of 120
            Pseudo Genes (frameshifted)       :: 67 of 120
            Pseudo Genes (incomplete)         :: 47 of 120
            Pseudo Genes (internal stop)      :: 34 of 120
            Pseudo Genes (multiple problems)  :: 23 of 120
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3016
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2167659-rid19724873.denovo.082"
                     /strain="1105170250"
                     /db_xref="taxon:1313"
     gene            578..1054
                     /locus_tag="VU534_002050"
     CDS             578..1054
                     /locus_tag="VU534_002050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEU1514568.1"
                     /translation="MVLDYFFDKNLVFCLEADSQEQLFDQVATLLEEREIVTPTYREA
                     LITREKSFPTGLDMEFLGKDLPNVAIPHTDIVHNLAEKVVVVRLEKPITFHNMIAPDK
                     EVEVSLLFFIINNSSSSQTNILAQLMDFFTGNGHLEDLSKISEPEALYTYIAEATA"
     gene            1092..1397
                     /locus_tag="VU534_002051"
     CDS             1092..1397
                     /locus_tag="VU534_002051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000590575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEU1514569.1"
                     /translation="MIKILAACGAGVNSSHQIKSALEEELSNRGYDVHCDAVMVKDVN
                     EDLMKGYDIFTPIAATDLGFEPGIPVIEAGPILFRIPAMSAPVFDNIEAAIKEHGLS"
     gene            1445..2920
                     /locus_tag="VU534_002052"
     CDS             1445..2920
                     /locus_tag="VU534_002052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000338710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HEU1514570.1"
                     /translation="MDAIFDLIGKVFNPILEMGGPVIMLIILTVLALLFGVKFSKALE
                     GGIKLAIALTGIGAIIGMLNTAFSASLAKFVENTGIQLSITDVGWAPLATITWGSAWT
                     LYFLLIMLIVNIVMLAMKKTDTLDVDIFDIWHLSITGLLIKWYADNNGVSQGVSLFIA
                     TAAIVLVGVLKIINSDLMKPTFDDLLNAPSSSPMTSTHMNYMMNPVIMVLDKIFEKFF
                     PGLDKYDFDAAKLNKKIGFWGSKFFIGFILGIVIGIMGTPHPIAGVADADKWRLVIKG
                     WLSLGLTAGVSLELFSLIGSWFIAAVEPLSQGITNVATKRLQGRKFNIGLDWPFIAGR
                     AEIWACANVLAPIMLIEAVLLSKVGNGILPLAGIIAMGVTPALLVVTRGKLLRMIIFG
                     TLLLPLFLLSGTLIAPFATELAKGVGAFPEGVSQTQLITHSTLEGPIEKLLGWTIGNT
                     TTGDIKAILGAVVFLVFYIGIFAWYRKQMIKRNEEYAAKAK"
BASE COUNT          929 a          573 c          570 g          944 t
ORIGIN      
        1 cgttgaatct ataacagtac gcatcgactg ctaaaacatt tctataaatc aattttcctt
       61 tcctaatcga tttgttcata tcttatttca atccattata aatagcgaga aatatctatc
      121 ctatcttcta gaatgtcttc caaacgagga aactctcgta aacaaagagg ttttagaggt
      181 ttatttacca tggactaaag ttgtacaaga aaagtgcaaa taagaaatct ccagattagg
      241 aactatccgt gagttcacta atctggagat ttttcaatag acttcgttat tgggcggtta
      301 cgatatgatc actgacttcg tcagtcttat ctacaacctc aaaacagtgt tttgagcaac
      361 ctgcgactag cttcctagtt tactctttga ttttcattga atattagaac agaaaaaatg
      421 cttggagtat ttgtttgtgt gtttattttt atataacaaa ctataaacaa aataaaaata
      481 taaaaaaaga gacaaaaaag aacagaaagt aattgacaac ggtttcatat agtgttatac
      541 ttatggcata aagttaatgg aaagaaggga aaaacttatg gtattagatt atttctttga
      601 caaaaacctt gtgttttgct tagaagcgga tagtcaagaa caactctttg atcaggttgc
      661 aactttattg gaagaacgag aaattgtcac tccaacttat cgtgaagcct tgatcacgcg
      721 tgaaaagtca tttccaactg gtttagatat ggaatttcta ggaaaggact tgccaaatgt
      781 agcgattcct cacacagata ttgttcataa tctagctgag aaagtggtgg ttgttcgatt
      841 agaaaaacca ataacttttc acaatatgat agctcctgat aaggaagtag aagtatccct
      901 actcttcttt atcattaata attcaagttc aagtcaaacg aacattcttg ctcagttaat
      961 ggacttcttc acaggaaatg gtcatcttga agacctatca aaaatttctg aaccagaagc
     1021 cctttatact tacattgctg aagcaaccgc ttaatcttgt ctattaaaaa ataaaatcgg
     1081 aggaaatcta aatgattaaa attcttgctg cctgcggtgc aggtgttaac tcaagtcacc
     1141 aaattaaaag tgctctagaa gaagaacttt caaaccgtgg ttatgatgtt cactgtgatg
     1201 cagtcatggt gaaagatgta aacgaagacc ttatgaaagg ttacgatatc tttacaccaa
     1261 tcgctgcaac agaccttggt tttgaaccag gtatcccagt tatcgaagct gggccaatct
     1321 tattccgtat cccagcaatg agcgctccag tatttgacaa tattgaagca gctattaaag
     1381 aacacggatt aagctaattc taatttgtta acattcatat aacatcaaaa agggaggaac
     1441 tgttatggat gcaatctttg acctaatcgg aaaggttttc aatcccatct tagaaatggg
     1501 tggacctgtc atcatgttaa tcattttgac agtattggct ttactttttg gagtgaaatt
     1561 ctccaaagcg cttgaaggtg gtatcaaact tgccatcgct cttacaggta tcggtgctat
     1621 catcggtatg ctaaacactg ctttctcagc atcactagca aaattcgttg aaaacactgg
     1681 tatccaattg agtattaccg acgttggttg ggcaccactt gctacaatca cttggggttc
     1741 tgcttggaca ctatacttct tgctcatcat gttgattgtc aacatagtga tgctagctat
     1801 gaagaaaaca gatacacttg atgtcgatat ctttgatatc tggcacttgt ctatcacagg
     1861 tctcttgatt aaatggtatg ctgataacaa tggtgtgagt caaggggttt cactctttat
     1921 tgctacagca gctatcgtcc ttgtcggtgt gttgaaaatt atcaactctg acttgatgaa
     1981 acctacattt gatgaccttc ttaacgcccc aagttcatca ccaatgacat caactcacat
     2041 gaactacatg atgaacccag ttatcatggt tttggataag atttttgaaa aattcttccc
     2101 aggccttgat aaatatgact ttgatgctgc taaattgaac aagaaaatcg gtttctgggg
     2161 atctaaattc ttcatcggtt tcatccttgg tatcgttatc ggtattatgg gaactccaca
     2221 tccaattgca ggtgttgcag atgcagataa atggcgtctt gttatcaaag gatggttgtc
     2281 tcttggtttg actgccggtg tatctttgga actcttctca cttatcggtt catggttcat
     2341 cgcagccgta gaaccactat cacaaggtat tacaaacgtt gctactaaac gtcttcaagg
     2401 acgtaaattc aatatcggtc ttgactggcc attcatcgct ggtcgtgctg aaatctgggc
     2461 ttgtgccaac gtacttgcac caatcatgtt gattgaagca gtgcttcttt caaaagttgg
     2521 aaatggtatc ttgccacttg caggtatcat cgctatgggt gttactccag ctctcttggt
     2581 tgtaactcgt ggtaaattgc tccgtatgat tatcttcgga acactcttgt tgccactctt
     2641 ccttctttca ggtacactta ttgcaccatt tgcaacagaa cttgctaaag gtgtaggtgc
     2701 cttcccagaa ggtgtgagcc aaactcaatt gattactcac tctactcttg aaggaccaat
     2761 cgaaaaactt cttggttgga caattggtaa cactacaact ggtgatatca aagcaatcct
     2821 tggtgcagta gtcttccttg tattctatat cggtatcttt gcttggtaca gaaaacaaat
     2881 gatcaaacgt aacgaagagt acgcagcaaa agcaaaataa tgcgctccta taaaatataa
     2941 actcaatgaa aatcaaagag caaactagga agctagccgc aggttgctca aaacacagtt
     3001 ttgaggttgt agataa
//
LOCUS       DAVFER010000083         2782 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1105170250
            SAMEA2167659-rid19724873.denovo.083, whole genome shotgun sequence.
ACCESSION   DAVFER010000083 DAVFER010000000
VERSION     DAVFER010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2167659
            Sequence Read Archive: ERR388902
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2782)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2782)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928716.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928716.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 04:07:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,118
            CDSs (total)                      :: 2,073
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 120
            CDSs (without protein)            :: 120
            Pseudo Genes (ambiguous residues) :: 0 of 120
            Pseudo Genes (frameshifted)       :: 67 of 120
            Pseudo Genes (incomplete)         :: 47 of 120
            Pseudo Genes (internal stop)      :: 34 of 120
            Pseudo Genes (multiple problems)  :: 23 of 120
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2782
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2167659-rid19724873.denovo.083"
                     /strain="1105170250"
                     /db_xref="taxon:1313"
     gene            70..1329
                     /locus_tag="VU534_002053"
     CDS             70..1329
                     /locus_tag="VU534_002053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRZ/ATZ family protein"
                     /protein_id="HEU1514571.1"
                     /translation="MKVFQHVNIVTCDQDFHVYLDGILAVKDSQIVYVGQDKPAFLEQ
                     AEQIIDYQGAWIMPGLVNCHTHSAMTGLRGIRDDSNLHEWLNDYIWPAESEFTPDMTT
                     NAVKEALTEMLQSGTTTFNDMYNPNGVDIQQIYQVVKTSKMRCYFSPTLFSSETETTA
                     ETISRTRSIIDEILKYKNPNFKVMVAPHSPYSCSRDLLEASLEMAKELNIPLHVHVAE
                     TKEESGIILKRYGKRPLAFLEELGYLDHPSVFAHGVELNEREIERLASSQVAIAHNPI
                     SNLKLASGIAPIIQLQKAGVAVGIATDSVASNNNLDMFEEGRTAALLQKMKSGDASQF
                     PIETALKVLTIEGAKVLGMENQIGSLEVGKQADFLVIQPQGKIHLQPQENMLSHLVYA
                     VKSSDVDDVYIAGEQVVKQGQVLTVEL"
     misc_feature    1404..1539
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            1578..2078
                     /locus_tag="VU534_002054"
     CDS             1578..2078
                     /locus_tag="VU534_002054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001287276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HEU1514572.1"
                     /translation="MSEAIIAKKAELVDVVAEKMKAAASIVVVDARGLTVEQDTVLRR
                     ELRGSEVEYKVIKNSILRRAAEKAGLEDLASVFVGPSAVAFSNEDVIAPAKILNDFSK
                     NAEALEIKGGAIEGAVASKEEILALATLPNREGLLSMLLSVLQAPVRNVALAVKAVAE
                     SKEDAA"
     gene            2154..2522
                     /gene="rplL"
                     /locus_tag="VU534_002055"
     CDS             2154..2522
                     /gene="rplL"
                     /locus_tag="VU534_002055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HEU1514573.1"
                     /translation="MALNIENIIAEIKEASILELNDLVKAIEEEFGVTAAAPVAVAAA
                     DAADAGAAKDSFDVELTSAGDKKVGVIKVVREITGLGLKEAKELVDGAPALVKEGVAT
                     AEAEEIKAKLEEAGASVTLK"
BASE COUNT          869 a          523 c          617 g          773 t
ORIGIN      
        1 acctacggca aagtgaatct gaagtggttt gaagagagta caacttgtct tttagaaaag
       61 gagcctataa tgaaagtctt tcagcatgta aatatcgtga cttgtgatca agatttccat
      121 gtttatcttg atggaatctt agcagtcaag gattctcaaa tcgtctatgt cggtcaagat
      181 aagccagcgt ttttagagca agctgagcag attatagact atcagggagc ttggattatg
      241 cctggtttgg tcaattgtca cacccattct gcaatgacag gtctgagagg gatccgagat
      301 gacagcaatc tccatgaatg gctcaatgac tatatttggc cagcagaatc tgagtttact
      361 cccgacatga ctaccaatgc ggtcaaagaa gccctgacag agatgctcca gtcaggaaca
      421 acaaccttta acgatatgta taatcccaat ggtgtggata tccagcaaat ttatcaggtg
      481 gtgaaaactt ccaagatgcg ttgttatttt tctccgactc tcttttcttc agagacagaa
      541 acaactgctg agactataag tagaactcga tccatcatag acgaaatctt aaaatataaa
      601 aatccaaatt tcaaggttat ggtagcacct cattctccgt atagctgcag tagagacttg
      661 ctggaagcga gtttggaaat ggcaaaagag ctaaatattc cgctccatgt ccatgtggcg
      721 gagaccaagg aggagtcagg aattatcctc aaacgatacg gcaaacgccc ccttgctttt
      781 cttgaagaac tgggttattt agatcatccg tccgtatttg ctcacggggt cgaattaaac
      841 gagagagaaa ttgaacgctt ggcatcttct caagtggcta tcgcccacaa tcctatcagt
      901 aacctcaaac tggcatcagg aattgctcca attatccagc tccaaaaagc gggagtagca
      961 gtcggaattg cgactgactc ggttgcttcc aataacaatc tagatatgtt tgaggaagga
     1021 aggactgcag ctcttcttca gaagatgaaa agtggggatg ccagccagtt tccaatcgaa
     1081 acagctctca aggtactgac aatcgaaggg gctaaggtcc ttggaatgga aaatcagata
     1141 ggaagtctgg aagtcggcaa gcaagcagat tttctggtca ttcaaccaca agggaaaatt
     1201 catctccaac ctcaggaaaa tatgctgtct cacctggttt atgcagttaa atctagtgat
     1261 gtagatgatg tttatatcgc cggagaacag gttgttaagc aaggtcaagt cctgacagta
     1321 gaactttaaa agaaaaatta cgaaaaattt taaaaaagtt tgcaaaaatc ttgcattctt
     1381 tttttgacta tgctatactt atatacggtt taaaaaaact gcctaagaca gtaggggagc
     1441 tcgactcata aatatcctac cgaggacaaa acgtatcatg taaaaagaag cgtattgtac
     1501 tttcgtgtct aggtttgggc gcgtttttct ttttgaaaaa ttccccaagc aaaataatta
     1561 cggaggtgaa cacactaatg agtgaagcaa ttattgctaa aaaagcggaa ctagttgacg
     1621 tagtagctga aaaaatgaaa gctgctgcat ctatcgtcgt tgtagacgct cgtggtttga
     1681 cagttgagca agatacagtt cttcgtcgtg agcttcgtgg aagcgaagtt gagtataaag
     1741 ttattaaaaa ctcaatcttg cgtcgtgcag ctgaaaaagc tggtcttgaa gatcttgcat
     1801 ctgtatttgt tggaccatct gcagtagcat tttctaatga agatgttatc gcaccagcga
     1861 aaatcttgaa cgacttttct aaaaacgctg aagcacttga aattaaaggt ggtgcaatcg
     1921 aaggcgctgt cgcatctaaa gaagagattc ttgcacttgc aactcttcca aaccgcgaag
     1981 gacttctttc tatgctcctt tctgtacttc aagcgccagt gcgcaacgtt gctcttgcag
     2041 tcaaagcggt tgcagaaagc aaagaagacg cggcttaatc ttaagctaca cagcgtagcc
     2101 tagctacgaa aaaaactatt ataaaattta aaacttattt ggaggaaata acaatggcat
     2161 tgaacattga aaacattatt gctgaaatta aagaagcttc aatccttgaa ttgaacgacc
     2221 ttgtaaaagc tatcgaagaa gaatttggtg taactgcagc tgctcctgta gctgttgctg
     2281 cagctgatgc agctgatgct ggtgctgcta aagattcatt cgacgttgaa ttgacatctg
     2341 caggcgacaa aaaagttggc gttatcaaag ttgtacgtga aatcactggt cttggtctta
     2401 aagaagctaa agaacttgtt gacggtgcac cagcacttgt taaagaaggc gttgcaactg
     2461 cagaagctga agaaatcaaa gctaaattgg aagaagctgg agcttcagtt actcttaaat
     2521 aatagagtat cgcaatttga ttgcggaatc cctatttacc agtctttgag agcgataagc
     2581 gattgataga aactgataaa ttgatttggt ttcctgccaa aaattctttg gcaggatttt
     2641 tgttttaata aactttcggg ggtagacact agattgtcta cccctttttt tgtgtttcgg
     2701 aggtaattat gcaaaaggaa ggacagtcat cacgtcaatt cgtgaagagt catctcatga
     2761 ctatcatggg agttgatatt gt
//
LOCUS       DAVFER010000084         2674 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1105170250
            SAMEA2167659-rid19724873.denovo.084, whole genome shotgun sequence.
ACCESSION   DAVFER010000084 DAVFER010000000
VERSION     DAVFER010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2167659
            Sequence Read Archive: ERR388902
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2674)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2674)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928716.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928716.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 04:07:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,118
            CDSs (total)                      :: 2,073
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 120
            CDSs (without protein)            :: 120
            Pseudo Genes (ambiguous residues) :: 0 of 120
            Pseudo Genes (frameshifted)       :: 67 of 120
            Pseudo Genes (incomplete)         :: 47 of 120
            Pseudo Genes (internal stop)      :: 34 of 120
            Pseudo Genes (multiple problems)  :: 23 of 120
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2674
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2167659-rid19724873.denovo.084"
                     /strain="1105170250"
                     /db_xref="taxon:1313"
     gene            complement(23..316)
                     /locus_tag="VU534_002056"
                     /pseudo
     CDS             complement(23..316)
                     /locus_tag="VU534_002056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001167986.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="integrase"
     gene            complement(483..708)
                     /locus_tag="VU534_002057"
                     /pseudo
     CDS             complement(483..708)
                     /locus_tag="VU534_002057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001824185.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            1556..2428
                     /locus_tag="VU534_002058"
     CDS             1556..2428
                     /locus_tag="VU534_002058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4300 family protein"
                     /protein_id="HEU1514574.1"
                     /translation="MKKSRKLATLGICSALFLGLAACQQQHATSEGTNQRQSSSAKVP
                     WKASYTNLNNQVSTEEVKSLLSAHLDPNSVDAFFNLVNDYNTIVGSTGLSGDFTSFTH
                     TEYDVEKISHLWNQKKGDFVGTNCRINSYCLLKNSVTIPKLEKNDQLLFLDNDAIDKG
                     KVFDSQDKEEFDILFSRVPTESTTDVKVHAEKMEAFFSQFQFNEKARMLSVVLHDNLD
                     GEYLFVGHVGVLVPADDGFLFVEKLTFEEPYQAIKFASKEDCYKYLGTKYADYTGEGL
                     AKPFIMDNDKWVKL"
     gene            complement(2574..2674)
                     /locus_tag="VU534_002059"
                     /pseudo
     CDS             complement(2574..2674)
                     /locus_tag="VU534_002059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
BASE COUNT          796 a          463 c          517 g          898 t
ORIGIN      
        1 aaataagata tgcacaaatt gattagaaag tcaaatgaat ttctacaaat gttttagcaa
       61 tcgtaatgta cttgtctaga ttcgatctga tatattttcg atttaatgat atggtattta
      121 aaacctccaa agtagcttac tccattcttt tacttacgtg agtgtagatg ttatttactg
      181 ttttagcgtt tttgtgttcc actctaacca ttatagcatt cttctcagct agtgtactaa
      241 ggagtgtgtg cctgaaaata tgggaactaa ggggctggtt tatcggtttc tctagtttag
      301 tatttgcctt ttgcaaagtg atcttaaatg cctttctcta aatttacata tcactattgt
      361 ttaacaaaat ctaatctatt ttaggtcact tattcttttt ttgaaatgta gaatgaactt
      421 tttcaaagtt tttcgaatct tttaaaatct gtttgcttta tatcgccatt ctcccccctt
      481 ttttaattct ccctatatag cctgacagct ttcccgatgg tacgaatatg gttgctttcg
      541 tctaggtgga tgtcggggta ttcgggattg agtttttttg aggcagcctt ggcggagttt
      601 cttgacatag ttagtgccgt ctacttggaa gatgccgatg gtattatagt caatctgtgg
      661 ggtattcttg ataaataggt agtcgctgtt tcttatcttt ggctccatgg acttgctgac
      721 gacataagcg attgggtcgt agtcgtctgg gataatggaa actccatatc taaatcgttg
      781 tcctgcatcg agcggctacc tgcagagata aactacctaa cacgagagta agtagtctgt
      841 ctgtagtcgt ccagtctgat gatttttacg atacttcgtt tttctgatca tacagttgcc
      901 tctcggcata ggtcagaact ttaccttgtc tgggtggttc ccgttggtcg tagatagatt
      961 ggatatcgct aggagaatcc ttttgaactg gaggaaagag ggcatcgatc aagctactga
     1021 atactttaac taagtcaaat atagtatttt tcttagtaga cctaaccctt ttttcataat
     1081 ttctaatggt gtttttactt atacctatct tagtacccaa ttcttattga gtccaaccat
     1141 tactagtcta tattgtttta tagttgattg agtttggaat agtacgctgt agctgctaaa
     1201 acatttctag aaattaattt gactttccta atagagttgt tcatatctta tttcaatcta
     1261 ttatgttttt cacctctaac aatcgcaatc tcttctttat ccatgaatga aatcgctttc
     1321 tatttttgta agtaaagcat aacacgaaat ccacgaaaat gaaaaccttt gttgtgtttt
     1381 cgtaaaaaat ttgttgacag agcacgaaac gcctactata attaaatcaa gcttaaggaa
     1441 ataacaaaaa aacaaatcgg agggaaagac gatgaacaca ttaaatgaga aagtaatcaa
     1501 tatctgtaaa gcaatagtta aagaaacttt aatccaagac atttaggaga aagaaatgaa
     1561 gaaatcaaga aaattagcca cattaggaat ctgttcagcc ttgtttttag gcttggctgc
     1621 ttgtcaacaa caacatgcta cttctgaggg gacgaatcaa aggcaaagca gttcagcgaa
     1681 agttccatgg aaagcttcat acaccaacct aaacaaccag gtaagtacag aagaggtcaa
     1741 atctctctta tcagctcact tggatccaaa tagtgttgat gcatttttta atctcgttaa
     1801 tgactataat accattgtcg gctcaactgg cttatcagga gatttcactt cctttactca
     1861 caccgaatac gatgttgaga aaatcagtca tctctggaat caaaagaagg gcgattttgt
     1921 tgggaccaac tgccgtatca atagttattg tcttttgaaa aattcagtca ccattccaaa
     1981 gcttgaaaag aatgaccagt tgcttttcct agataatgat gcgattgata aaggaaaggt
     2041 ctttgattca caagataagg aagagtttga tattctattt tcgagagttc caactgagtc
     2101 aactacagat gtcaaggttc acgctgaaaa gatggaagca ttcttctcac aatttcaatt
     2161 caatgaaaaa gctcgaatgc tgtctgtagt cttgcacgac aatttggatg gcgagtatct
     2221 gtttgtaggc cacgttgggg tcttagtacc tgctgatgac ggtttcttat ttgtagagaa
     2281 attgactttc gaagagccct accaagcgat taaatttgct agtaaggaag attgctacaa
     2341 gtatttgggc accaagtatg cggattatac aggcgaggga ctggctaagc cttttatcat
     2401 ggataatgat aagtgggtta aactttaata gtgttatgat atgacagtaa tcttaggatt
     2461 tttatttcta tttttgataa gttggtgggt tatttcaatc gttaatagcc agaaaccacg
     2521 caaaaatgaa acatttattg gctatgtcca aagatacgat attgatggga atggctatca
     2581 atcattaccg tgtcctcaga actgagagga gttcttgaaa tcgtaacacc actttgaaca
     2641 agagttactt caacccattg gctccgacgg atta
//
LOCUS       DAVFER010000085         2577 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1105170250
            SAMEA2167659-rid19724873.denovo.085, whole genome shotgun sequence.
ACCESSION   DAVFER010000085 DAVFER010000000
VERSION     DAVFER010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2167659
            Sequence Read Archive: ERR388902
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2577)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2577)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928716.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928716.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 04:07:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,118
            CDSs (total)                      :: 2,073
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 120
            CDSs (without protein)            :: 120
            Pseudo Genes (ambiguous residues) :: 0 of 120
            Pseudo Genes (frameshifted)       :: 67 of 120
            Pseudo Genes (incomplete)         :: 47 of 120
            Pseudo Genes (internal stop)      :: 34 of 120
            Pseudo Genes (multiple problems)  :: 23 of 120
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2577
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2167659-rid19724873.denovo.085"
                     /strain="1105170250"
                     /db_xref="taxon:1313"
     gene            165..479
                     /locus_tag="VU534_002060"
     CDS             165..479
                     /locus_tag="VU534_002060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1514575.1"
                     /translation="MWVLGFILFMIFFYSNNSKKIKKLENKIKRLERKEKGNAEMSRL
                     LQEMIGKEPIITGVYIGPDNWEVVDVDEEWVKLRRVDNTGKEKFKLQRIEDIQTVEFD
                     GE"
     gene            489..695
                     /locus_tag="VU534_002061"
     CDS             489..695
                     /locus_tag="VU534_002061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001176227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU1514576.1"
                     /translation="MQLKNRLKELRARDGLNQTDLAKLAGVSRQTISLLERDEYTPSI
                     IIALKISQIFNETVESVFRLEEDE"
     gene            695..892
                     /locus_tag="VU534_002062"
     CDS             695..892
                     /locus_tag="VU534_002062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001046145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1514577.1"
                     /translation="MNKYKVIYYVVVIALLVSVFLLIGMDLSWFNPYQSDQFVWVYFA
                     LIPVIEWIEKKSKNLASEKGE"
     gene            948..1628
                     /locus_tag="VU534_002063"
     CDS             948..1628
                     /locus_tag="VU534_002063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001833114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3169 family protein"
                     /protein_id="HEU1514578.1"
                     /translation="MGMFVGMFKARVESHEIILDVKALMPWISAICLLIGFISMFLTF
                     NFLKKSRKFHSLYQEEMDDDLNETYYVQMYRNLEFGTIAFNITGVAIPLAIFISLSEV
                     IILHTNPQTFFLSFLLFVVFLVAQKSLFKTIAIVRQFDLEFFATPKDVLNYINSYDEG
                     ERQANLEQSFRILFQLHQYVLPALYIFLIIISFLTGEIQLLAFLLVGAIHVYINVMQL
                     PMVKRYFK"
     gene            1640..2281
                     /locus_tag="VU534_002064"
     CDS             1640..2281
                     /locus_tag="VU534_002064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU1514579.1"
                     /translation="MKLLKNLGWILLALLSFLFIYGFIQGLATASLALGASPYAVTLL
                     YVALAGVYVYGIYKWYQKAPVHIEKSGFNRFIWLPVLVWFLSLVVQFFLPDDPSVNQQ
                     IATDLTLSQPLFSFFAVVIFAPLTEEIVFRGMLARYLFPKQDNSKRTLIFLLVSSLLF
                     ALIHFPGDVQQFFVYFSLGFSLGLAYISRKGLVYSISLHALNNLVGFLMILML"
     gene            2299..2529
                     /locus_tag="VU534_002065"
     CDS             2299..2529
                     /locus_tag="VU534_002065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000832182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1514580.1"
                     /translation="MKRVILLAVIQAVVLFFIIGALAYAFKGDFFYNYLAVVFAPIAG
                     VLRFGTAYITEIVLPRKAAEIAEKRKAGKNSK"
BASE COUNT          757 a          422 c          523 g          875 t
ORIGIN      
        1 gaagagtatt aatgatagat aaagtggtca ggaacctact cctgaccttt ttcttttgca
       61 aaatgacaaa aatcataatt tttttgacaa ctatacttgt caaaaagaaa aagatatgtt
      121 acaatgaatt caagttaaga aataggaagc agaaaggagt tataatgtgg gtactaggat
      181 ttatactatt tatgattttc ttttattcta ataattctaa aaaaatcaag aaactagaga
      241 ataaaatcaa aagacttgag cgaaaagaga aaggaaacgc agaaatgtcg agattattac
      301 aagaaatgat tggaaaggaa ccaattataa cgggagtgta tattgggcca gataactggg
      361 aagttgtgga tgttgatgag gaatgggtaa agctacgacg tgtagataat acgggaaaag
      421 aaaaattcaa gttgcaacgt attgaggata tccaaaccgt tgaatttgac ggagagtagg
      481 tgtgtaacat gcaactaaaa aatcgtctaa aagagcttcg agctcgcgat ggtctcaatc
      541 aaaccgacct agccaaactg gcaggggttt ccagacagac cattagccta ctagaacggg
      601 atgagtacac cccatccatt atcattgccc tgaaaatatc tcaaattttc aacgaaacag
      661 tcgaatcggt atttcgtttg gaggaggacg agtgatgaac aagtataaag tgatttatta
      721 tgtagtggtc atagctttat tagtcagcgt atttctactg attgggatgg acctaagctg
      781 gtttaatccc tatcaaagcg accaatttgt ttgggtctac tttgctctca tcccagtaat
      841 tgaatggatt gaaaagaaat ccaaaaatct agcaagtgaa aaaggagaat gaatatgaaa
      901 aagaaacgta gattgttatt tttgatgtct attgtcttgg ggggttcttg ggcatgtttg
      961 tagggatgtt taaggcacgt gtcgaatccc acgaaattat tttagatgta aaagccttga
     1021 tgccatggat atcagctatt tgtttactga taggtttcat tagtatgttt ttgactttca
     1081 atttcttaaa gaaaagcaga aaatttcatt ctttgtatca agaggaaatg gatgacgatc
     1141 tgaatgaaac ctattatgtg caaatgtatc ggaatcttga gtttggaacc attgctttta
     1201 atattacagg tgtagcgatt ccattggcta tttttatttc attaagtgag gtgattatat
     1261 tgcatacaaa ccctcaaaca tttttccttt ctttcttact ctttgtggta ttcttagtcg
     1321 ctcaaaaatc tctttttaaa accattgcga ttgttcgtca gtttgatttg gaatttttcg
     1381 ctacaccaaa ggatgtcttg aactatataa attcttatga tgaaggggag cgtcaggcta
     1441 atttggaaca gagttttcga attttattcc aattacacca atatgtctta ccagccttat
     1501 atatttttct tattatcatt tctttcttga caggagagat tcagttacta gctttcttgc
     1561 ttgtaggagc catccatgtt tatatcaatg tgatgcagtt acctatggta aaacgttatt
     1621 tcaaataaag gagttatcta tgaaattact taaaaacctt ggctggattc ttctagccct
     1681 tctatccttt ttatttatct atggctttat tcaggggctc gcgactgcgt cgcttgcttt
     1741 aggcgcttca ccctatgctg ttactctact ctatgtggcc ttggctggag tatatgtgta
     1801 cggcatttac aaatggtatc agaaggctcc tgttcatatt gagaagagcg gctttaatcg
     1861 atttatttgg cttcctgtct tggtttggtt cttatctctg gtcgttcaat tcttcttgcc
     1921 agatgatcct tcagtaaatc agcaaatagc gacagacttg accttgtctc aaccactttt
     1981 ctcattcttt gctgtggtta tttttgctcc tttgacggaa gagattgttt ttagagggat
     2041 gttagcacgc tatctctttc ctaagcagga caatagtaaa cgaaccctga tttttcttct
     2101 ggtatctagt cttctatttg ccttgattca ttttccaggt gatgtgcaac aattttttgt
     2161 ctattttagc cttggtttta gtttgggttt ggcttacatt agcagaaaag gtctggtcta
     2221 cagtatttct cttcacgctt tgaataattt agtcggcttt ttgatgattc tcatgctata
     2281 atagagtcag gaggtcacat gaaacgagta attttattag cagtgattca ggcagtcgtt
     2341 ctatttttca tcattggagc gctagcttat gccttcaaag gcgatttctt ctataactat
     2401 ctagcagttg tctttgctcc tattgcaggt gtactgcgtt ttgggacggc ttacataacg
     2461 gaaattgtct tgcctcgaaa ggcagccgaa atcgctgaaa agcgtaaagc aggcaaaaat
     2521 tcaaaataaa agagtccggt gaagttcatc ggatttttgt attatactca atgaaaa
//
LOCUS       DAVFER010000086         2044 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1105170250
            SAMEA2167659-rid19724873.denovo.086, whole genome shotgun sequence.
ACCESSION   DAVFER010000086 DAVFER010000000
VERSION     DAVFER010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2167659
            Sequence Read Archive: ERR388902
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2044)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2044)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928716.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928716.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 04:07:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,118
            CDSs (total)                      :: 2,073
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 120
            CDSs (without protein)            :: 120
            Pseudo Genes (ambiguous residues) :: 0 of 120
            Pseudo Genes (frameshifted)       :: 67 of 120
            Pseudo Genes (incomplete)         :: 47 of 120
            Pseudo Genes (internal stop)      :: 34 of 120
            Pseudo Genes (multiple problems)  :: 23 of 120
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2044
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2167659-rid19724873.denovo.086"
                     /strain="1105170250"
                     /db_xref="taxon:1313"
     gene            complement(<1..196)
                     /locus_tag="VU534_002066"
     CDS             complement(<1..196)
                     /locus_tag="VU534_002066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1514581.1"
                     /translation="MKKTLTPTKESIDSLRNYEASKQLTDTRFKRLVGVQRTTFKEML
                     AVLKTAYQLKHAKGGRKPKLS"
     gene            complement(141..323)
                     /locus_tag="VU534_002067"
     CDS             complement(141..323)
                     /locus_tag="VU534_002067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEU1514582.1"
                     /translation="MDLKFEGVDLEYKKAKNNLPESFWETYSAFANTNGGKIILGIDE
                     KNIDTYQRVNRLPAKL"
     gene            658..>2044
                     /gene="pcpA"
                     /locus_tag="VU534_002068"
     CDS             658..>2044
                     /gene="pcpA"
                     /locus_tag="VU534_002068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000753868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein PcpA"
                     /protein_id="HEU1514583.1"
                     /translation="MKKTTILSLTTAAVILAAYVPNEPILADTPSSEVIKETKVGSII
                     QQNNIKYKVLTVEGNIGTVQVGNGVTPVEFEAGQDGKPFTIPTKITVGDKVFTVTEVA
                     SQAFSYYPDETGRIVYYPSSITIPSSIKKIQKKGFHGSKAKTIIFDKGSQLEKIEDRA
                     FDFSELEEIELPASLEYIGTSAFSFSQKLKKLTFSSSSKLELISHEAFANLSNLEKLT
                     LPKSVKTLGSNLFRLTTSLKHVDVEEGNESFASVDGVLFSKDKTQLIYYPSQKNDESY
                     KTPKETKELASYSFNKNSYLKKLELNEGLEKIGTFAFADAIKLEEISLPNSLETIERL
                     AFYGNLELKELILPDNVKNFGKHVMNGLPKLKSLTIGNNINSLPSFFLSGVLDSLKEI
                     HIKNKSTEFSVKKDTFAIPETVKFYVTSEHIKDVLKSNLSTSNDIIVEKVDNIKQETD
                     VAKPKKNSNQGV"
BASE COUNT          739 a          288 c          324 g          693 t
ORIGIN      
        1 ggcttaattt aggttttcgt ccaccttttg cgtgtttaag ttgataagct gtttttaata
       61 cagctaacat ctctttaaaa gtcgtgcgct gaacaccaac aagacgctta aatcgtgtat
      121 cagttaattg tttacttgct tcataatttc gcagggagtc tattgactct ttggtaggtg
      181 tcaatgtttt tttcatctat cccgagaatt attttcccgc catttgtatt tgcaaatgct
      241 gagtaggttt cccagaaaga ctctggaaga ttgtttttag cttttttgta ttctaaatca
      301 accccttcaa attttaagtc catatttttc ctttacatct gttttttgtg gttctggtat
      361 ttgttcaagt tgagtgataa tatagcgaat tgaatttcga gagtttttac tcagttaatt
      421 tcttttttaa cctactttaa tttctttttt aacacgggtt aaaaaagaaa ttaaagtagg
      481 ttaatttttc ttgacttaaa atttaaaaat gatatactgt gtttatggag agatgacaat
      541 ttataaaatg tactactcta ttctactaga taatgattga ataaaacttt ttataacaac
      601 ggctagcaaa gttataattt tatatctatt agaaaataaa tatgtaagga aatttaaatg
      661 aaaaaaacta caatattatc attaactaca gctgcggtta ttttagcagc atatgtccct
      721 aatgaaccaa tcctagcaga tactcctagt tcggaagtaa tcaaagagac taaagttgga
      781 agtattattc aacaaaataa tatcaaatat aaggttctaa ctgtagaagg taacatagga
      841 actgttcaag tgggtaatgg agttactcct gtagagtttg aagctggtca agatggaaaa
      901 ccattcacga ttcctacaaa aatcacagta ggtgataaag tatttaccgt tactgaagta
      961 gctagtcaag cttttagtta ttatccagat gaaacaggta gaattgtcta ctatcctagc
     1021 tctattacta tcccatcaag cataaaaaaa atacaaaaaa aaggcttcca tggaagtaaa
     1081 gctaaaacta ttatttttga caaaggcagt cagctggaga aaattgaaga tagagctttt
     1141 gatttttctg aattagaaga gattgaattg cctgcatctc tagaatatat tggaacaagt
     1201 gcattttctt ttagtcaaaa attgaaaaag ctaacctttt cctcaagttc aaaattagaa
     1261 ttaatatcac atgaggcttt tgctaattta tcaaatttag agaaactaac attaccaaaa
     1321 tcggttaaaa cattaggaag taatctattt agactcacta ctagcttaaa acatgttgat
     1381 gttgaagaag gaaatgaatc gtttgcctca gttgatggtg ttttgttttc aaaagataaa
     1441 acccaattaa tttattatcc aagtcaaaaa aatgacgaaa gttataaaac gcctaaggag
     1501 acaaaagaac ttgcatcata ttcgtttaat aaaaattctt acttgaaaaa actcgaattg
     1561 aatgaaggtt tagaaaaaat cggtactttt gcatttgcag atgcgattaa acttgaagaa
     1621 attagcttac caaatagttt agaaactatt gaacgtttag ccttttacgg taatttagaa
     1681 ttaaaagaac ttatattacc agataatgtt aaaaattttg gtaaacacgt tatgaacggt
     1741 ttaccaaaat taaaaagttt aacaattggt aataatatca actcattgcc gtccttcttc
     1801 ctaagtggcg tcttagattc attaaaggaa attcatatta agaataaaag tacagagttt
     1861 tctgtgaaaa aagatacatt tgcaattcct gaaactgtta agttctatgt aacatcagaa
     1921 catataaaag atgttcttaa atcaaattta tctactagta atgatatcat tgttgaaaaa
     1981 gtagataata taaaacaaga aactgatgta gctaaaccta aaaagaattc taatcaggga
     2041 gtag
//
LOCUS       DAVFER010000087         1860 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1105170250
            SAMEA2167659-rid19724873.denovo.087, whole genome shotgun sequence.
ACCESSION   DAVFER010000087 DAVFER010000000
VERSION     DAVFER010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2167659
            Sequence Read Archive: ERR388902
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1860)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1860)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928716.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928716.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 04:07:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,118
            CDSs (total)                      :: 2,073
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 120
            CDSs (without protein)            :: 120
            Pseudo Genes (ambiguous residues) :: 0 of 120
            Pseudo Genes (frameshifted)       :: 67 of 120
            Pseudo Genes (incomplete)         :: 47 of 120
            Pseudo Genes (internal stop)      :: 34 of 120
            Pseudo Genes (multiple problems)  :: 23 of 120
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1860
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2167659-rid19724873.denovo.087"
                     /strain="1105170250"
                     /db_xref="taxon:1313"
     gene            complement(3..968)
                     /locus_tag="VU534_002069"
     CDS             complement(3..968)
                     /locus_tag="VU534_002069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000444451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEU1514584.1"
                     /translation="MESKVTIIMQEMLPLLNNEQLLALRESLEHHLVDGKKQQKYSNN
                     NLLQLFITAKQVEGCSSKTIRYYQRTIENLFNAIKESVTQLTTDDLRSYLANYQSEKD
                     CSKANLDNIRRILSSFFAWLEQEEYIIKNPIRRIKKIKTEQNVKETYTDEHLEIMRDN
                     CENLRDLAIIDLLASTGMRVGELVQLNRSDIDFENRECVVFGKGKKERPVYFDARTKI
                     HLRNYLNDRKDSHPALFVTLVGKVQRLGIAGVEIRLRKLGDKLGIQKVHPHKFRRTLA
                     TKAIDKGMPIEQVQKLLGHSKIDTTLAYAMVNQNNVKHSHQKFIS"
     gene            complement(1086..1499)
                     /locus_tag="VU534_002070"
     CDS             complement(1086..1499)
                     /locus_tag="VU534_002070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000158364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="HEU1514585.1"
                     /translation="MTIYLTEKQIEKINALAIQRYSPNEKIQTVSPSALNMIVNLPEQ
                     FVFGKPLYPTIFDKATILFVQLIKKHVFANANKRTAFFVLVKFLQLNGYRFSVTVEEA
                     VKMCVTIAVEALTDEKMTSYSKWISEHSVREKVKK"
     gene            complement(1496..1732)
                     /locus_tag="VU534_002071"
     CDS             complement(1496..1732)
                     /locus_tag="VU534_002071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000260605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HEU1514586.1"
                     /translation="MVVKTRKQGNSITITIPSEFNIPSGVKYEAKLLPSGEIIFTPEE
                     LGQQVSYVSDDAFDLNLDKIFDEYDDVFKALVEK"
BASE COUNT          544 a          362 c          274 g          680 t
ORIGIN      
        1 ttttaagaga tgaatttttg gtgtgaatgc ttgacattat tttgattgac catggcatag
       61 gccaaggttg tgtcaatctt gctatgacct agcagttttt ggacttgttc gataggcata
      121 cctttatcaa ttgccttagt cgctaaagtt cttctgaact tatgtgggtg aaccttttgt
      181 atgccgagtt tgtctcctaa ctttcttaag cgaatctcta caccagcaat tccaagcctc
      241 tggacttttc caactagcgt tacaaaaaga gcagggtgac tatcttttct gtcgttaaga
      301 taatttctta aatgaatttt cgtacgagcg tcaaaatata ctggtctctc cttctttcct
      361 ttaccaaaga caacacactc tctgttttca aaatcaatat ctgaacgatt caactgtaca
      421 agctccccta cacgcatacc tgtcgatgct agtaggtcta ttattgccaa atctctcaaa
      481 ttttcacagt tatcacgcat aatttccaaa tgttcatcag tataagtttc cttcacattt
      541 tgctcagtct taattttctt tatccgtcga atgggatttt taatgatata ttcctcttgc
      601 tcaagccaag caaaaaaaga agacaatata cgcctaatat tgtctaaatt tgccttacta
      661 caatcctttt cagactggta atttgctaaa taactcctta aatcatctgt tgtgagttgt
      721 gtcacagact ctttaatagc attaaacaag ttttcaatcg tcctctgata ataacgaatt
      781 gtttttgagc tacagccctc tacctgcttg gcggtaataa atagttgcaa caggttatta
      841 ttcgaatact tctgctgctt ttttccgtct actagatgat gttctaaact ctctctcaac
      901 gctagtaatt gttcattatt taaaagaggt aacatttctt gcatgataat tgtaactttt
      961 gattccataa tttctcactt tcttattcat caataaaaag agacaatatc agtttctgca
     1021 ttacagaatt ctaatattgt ctgttcattt attttcttgt gctcattcaa atccagcata
     1081 ctaggttact ttttgacctt ttctctaaca gaatgttcag aaatccattt ggagtagctt
     1141 gtcatttttt catcagttaa agcttctact gcgatggtta cacacatttt tactgcttct
     1201 tctaccgtta cagaaaaacg atagccgttt aattgtaaaa atttgaccaa aacgaagaaa
     1261 gcagttcttt tattagcatt agcaaaaaca tgcttcttta tcaattggac aaatagtatc
     1321 gttgctttat caaaaattgt tggataaaga ggcttcccaa agacaaattg ttctggtaag
     1381 ttcacaatca tatttaaggc agaaggacta actgtttgaa ttttctcatt tggagaatac
     1441 cgttgaattg ctaaagcatt tattttttca atttgctttt ctgtcaaata gattgtcatt
     1501 tttccaccaa agctttgaaa acatcgtcgt attcgtcaaa tattttatct aaatttaagt
     1561 caaaggcatc atcagataca taagaaacct gctgccccaa ttcttcagga gtaaagataa
     1621 tctcaccact tggtaacaat ttcgcttcgt atttaacacc acttggaata ttaaattcac
     1681 ttggaatcgt aatggtgatt gaatttcctt gttttcttgt ttttactacc atctgatttc
     1741 ctcctttgaa gtattataac aaatcattac cgtaattaca atggcagaat atcagccaaa
     1801 atactcctgc atcagagatt tcttcaaagt ttcaagttct tccagagatt tttggattgc
//
LOCUS       DAVFER010000088         1806 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1105170250
            SAMEA2167659-rid19724873.denovo.088, whole genome shotgun sequence.
ACCESSION   DAVFER010000088 DAVFER010000000
VERSION     DAVFER010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2167659
            Sequence Read Archive: ERR388902
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1806)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1806)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928716.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928716.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 04:07:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,118
            CDSs (total)                      :: 2,073
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 120
            CDSs (without protein)            :: 120
            Pseudo Genes (ambiguous residues) :: 0 of 120
            Pseudo Genes (frameshifted)       :: 67 of 120
            Pseudo Genes (incomplete)         :: 47 of 120
            Pseudo Genes (internal stop)      :: 34 of 120
            Pseudo Genes (multiple problems)  :: 23 of 120
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1806
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2167659-rid19724873.denovo.088"
                     /strain="1105170250"
                     /db_xref="taxon:1313"
     gene            complement(<1..172)
                     /locus_tag="VU534_002072"
     CDS             complement(<1..172)
                     /locus_tag="VU534_002072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU1514587.1"
                     /translation="MVNCEQLEAYRQLEEAALVGCWAHVRRKFFEVPPKQADKSSLGA
                     KGLAYCDQLFSLE"
     gene            complement(245..1021)
                     /locus_tag="VU534_002073"
     CDS             complement(245..1021)
                     /locus_tag="VU534_002073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000457791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU1514588.1"
                     /translation="MFAHLDNSVFLKRNKIWKKTLTYPVEREEITYKRKKAKGKRQAL
                     LAQFDSEEVHHQVEESICPDCQGDLKEIGATLQRQELVFIPAQLKRIDHIQHAYKCQA
                     CSDKNPSDKIVKAPIPKAPLAHSLGSASIIAHTIHQKFNLKVPNYRQEEDWAKMGLPI
                     TRKEIANWHIKASQYYLEPLYNLLREKLLEQALLHADETSYRVLESDSQLPYYWTFLS
                     GKAENQAITLYHHDQRRSGLVVQEFLGDYSGYVHCDMLRQ"
     gene            complement(945..1139)
                     /locus_tag="VU534_002074"
     CDS             complement(945..1139)
                     /locus_tag="VU534_002074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU1514589.1"
                     /translation="MKIIQQQSATIDSLTNELALLREQVAYLTQKLYGKSSEKSVCPS
                     GQLSLFEEEQNMEEDSDLPS"
     gene            complement(1216..1556)
                     /gene="tnpB"
                     /locus_tag="VU534_002075"
                     /pseudo
     CDS             complement(1216..1556)
                     /gene="tnpB"
                     /locus_tag="VU534_002075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
     gene            complement(1537..1722)
                     /locus_tag="VU534_002076"
     CDS             complement(1537..1722)
                     /locus_tag="VU534_002076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001136123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1514590.1"
                     /translation="MPQPIVPVEIPQSRRFDSKKRNDILLKIRIGKLEVSFFQSLNLE
                     MVEQLLDKVLLYDNSSI"
BASE COUNT          526 a          381 c          338 g          561 t
ORIGIN      
        1 tttccaagga aaataactga tcacaataag ctaaaccttt agctcctaag gatgatttat
       61 ctgcttgctt ggggggcact tcaaaaaact tccttctcac atgcgcccaa catccaacaa
      121 gtgcagcttc ttccagttga cgataagctt ctagctgttc gcagtttacc aagcttagcg
      181 tcgccttact cctaaacctt ggactgctat cgcataggca gaactagagg actaaagtcc
      241 taagttactg ccgcaacatg tcacaatgaa catagccaga ataatctcct aggaattctt
      301 gtactactaa accactccga cgctgatcat ggtggtacag cgtgattgct tgattctcag
      361 ctttcccaga caaaaaagtc caatagtaag gcaactgact atcactctct agaacccgat
      421 aagaggtttc atccgcatga agaagagctt gttctaacaa cttttctcgt aaaagattat
      481 aaaggggctc caaatagtat tgactcgcct tgatatgcca attagcaatt tccttacgtg
      541 tgattggtaa acccatctta gcccaatctt cttcttggcg ataattgggt accttcagat
      601 taaacttctg atggatggtg tgagcgataa tagaagctga gccaaggcta tgcgccaaag
      661 gggctttagg aataggagct ttcacgattt tatcactcgg atttttatca ctgcatgctt
      721 ggcacttata agcgtgttgg atatgatcta ttcgttttaa ttgcgcagga ataaagacta
      781 attcttgtcg ttgaagggtt gctccaatct cttttagatc tccctgacaa tcagggcaaa
      841 tgctctcttc tacttgatga tgaacttctt ctgaatcaaa ttgggcaaga agagcttgac
      901 gtttcccttt agctttctta cgtttatagg tgatttcttc tctttcaact gggtaagtca
      961 gagtcttctt ccatattttg ttcctcttca aaaagactga gttgtccaga tgggcaaaca
     1021 cttttctcag aggattttcc atagagcttt tgcgttagat aagccacttg ttcacgaaga
     1081 agggcaagtt cattggtgag actatcaatt gtagcactct gttgttgaat gattttcaat
     1141 cttcttccat gggcttcctc tccttatttc ctaactttat tataactaaa aagaaagtcc
     1201 tcatttcaat agaaatcacg actttctgat aaatttattt ttggagtgat agaaaagccc
     1261 ttcataagcc aatctacttg ttcaggtgtg agagctttga catccttttc tgtactgggc
     1321 caagtcagtt ttccgttctc aaagcgttta tatagtagcc aaaatccttg accatcccag
     1381 taaagggctt taaagcggtc tttacgtcca ccacaaaaga gaaaaacttg accggagaaa
     1441 ggatctaatt caaagtgggt tttaaccaga taagccaatg aatcaatgcc ttgcctcata
     1501 tccgttttcc cacatacgag atagacctgc cctaggctag atagatgaat tgtcatagag
     1561 caacacttta tccaaaagct gttctaccat ttcgagattg agagattgaa aaaaacttac
     1621 ttcaagcttg ccaatacgaa ttttaagcag aatatcattt ctctttttag aatcaaaacg
     1681 acgagattgt ggaatctcta caggaacaat aggttgtggc attaaaatat cctccaatag
     1741 ttttacttta ctaatagtat acaggaggaa ctccatgaat gatagatacc ttgttatgac
     1801 gcgatt
//
LOCUS       DAVFER010000089         1750 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1105170250
            SAMEA2167659-rid19724873.denovo.089, whole genome shotgun sequence.
ACCESSION   DAVFER010000089 DAVFER010000000
VERSION     DAVFER010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2167659
            Sequence Read Archive: ERR388902
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1750)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1750)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928716.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928716.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 04:07:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,118
            CDSs (total)                      :: 2,073
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 120
            CDSs (without protein)            :: 120
            Pseudo Genes (ambiguous residues) :: 0 of 120
            Pseudo Genes (frameshifted)       :: 67 of 120
            Pseudo Genes (incomplete)         :: 47 of 120
            Pseudo Genes (internal stop)      :: 34 of 120
            Pseudo Genes (multiple problems)  :: 23 of 120
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1750
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2167659-rid19724873.denovo.089"
                     /strain="1105170250"
                     /db_xref="taxon:1313"
     gene            complement(1..1152)
                     /gene="ltrA"
                     /locus_tag="VU534_002077"
                     /pseudo
     CDS             complement(1..1152)
                     /gene="ltrA"
                     /locus_tag="VU534_002077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
BASE COUNT          453 a          419 c          291 g          587 t
ORIGIN      
        1 ctgagctact aattgataat ggtcgcccca gccagatacc ttatctgcta tccatttagg
       61 aactcctaac ttaagcaatc cccataatcg tctcgatttc ttcttccatt gcttccagat
      121 aatcactcgt aggcgagtac gcaagcgctc atctatgctg gcgactatac ttttcatatt
      181 tcccaatgag caatagttta tccatcctcg aatagacaaa ttcagttgct caatacgtct
      241 tgttaggtct atactccatt tcctctgtgt tagtttcttc aatttaaact taaatctccg
      301 aacactatct tgatgtggac ggcttttcca accatctgat aatttccaga acccaaaacc
      361 tagatatttc aactctcttg gtcatgttta ctttcaaacc tagccgtttc tcaataaaac
      421 gactgactga atacatcaca cgcttagagg ctgcctcgct tccgaccgta atcacacaat
      481 catctgcgta gcgcacaaat cgaagtcccc tcttttctaa ttccttgtcc aattcattaa
      541 gcatgatatt ggataagaga ggagataaat ttcctccctg tggtgtacca actagtgttt
      601 tataacgttg accattaatg ataacacctg aatgaagata cttacgaatc aaggattccg
      661 tatctccgtc ttcgataatg ttatgtacta aggacatcaa tctatcttga ggaactgtat
      721 cgaaaaattt ctctaggtct aatccactat ccactcatag ccgtcattta agtattctaa
      781 gagcttcatg atggcttttt cacatgacct atttggtctg aaaccataac tcgtatctga
      841 gaaatggggt tcacaaatgg ggctcatgac ttggacaatg gcctgttgaa tcattctatc
      901 cataactgtt ggaattccta gttgacggat gcctccgtct ggtttaggta tctcaactct
      961 aagaactggt tgaggcttat attttctctg ttttatcagt tccttagtca agcgccagtt
     1021 ttgtctgaga taattatcca tctcttcgat agtcattcca tcaatcccag ctgagccttt
     1081 attggatttt acttgattgt aggcttccag catattttcg cgtgataata tcttatctag
     1141 cagttttgac atgtgcgtat tcctttctta ttttggtgcc tgagggacat cttatattgg
     1201 tgaaccttca tctagtcatt acgtgtcaaa gtccagttct atcagaccac tcattttaca
     1261 gacacaagtg aagtaggatt acttcgatct gtcgttttct ctttctagcg acagacctca
     1321 aacagtctct ccccagactg tttgagtatt caccccttcg ctccacttcc attacggaag
     1381 tttcctcact actatgggct cggctgactt ctcatgattc gttgttacta cgctttcagc
     1441 gctcatgaaa cctcacggga taagtcgtac atctttcctc gtttatacaa gatatgagga
     1501 cgttaaaagg ttacagtgaa aataggaaat ctgacgcaga gtctttagac tctagaaaga
     1561 tttatctttt tcacacaaac cttagtccga attcaattac tctcgtgatt tacacatata
     1621 ggttacgact acctttttgg actttagagt ttgaagcctc cttatccgct atatacgcct
     1681 tactatcacg ttcctgttcg tagagccacg atttcgctat cccttcctct ccctgctacc
     1741 tcacgatagt
//
LOCUS       DAVFER010000090         1661 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1105170250
            SAMEA2167659-rid19724873.denovo.090, whole genome shotgun sequence.
ACCESSION   DAVFER010000090 DAVFER010000000
VERSION     DAVFER010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2167659
            Sequence Read Archive: ERR388902
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1661)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1661)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928716.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928716.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 04:07:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,118
            CDSs (total)                      :: 2,073
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 120
            CDSs (without protein)            :: 120
            Pseudo Genes (ambiguous residues) :: 0 of 120
            Pseudo Genes (frameshifted)       :: 67 of 120
            Pseudo Genes (incomplete)         :: 47 of 120
            Pseudo Genes (internal stop)      :: 34 of 120
            Pseudo Genes (multiple problems)  :: 23 of 120
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1661
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2167659-rid19724873.denovo.090"
                     /strain="1105170250"
                     /db_xref="taxon:1313"
     gene            145..1491
                     /locus_tag="VU534_002078"
     CDS             145..1491
                     /locus_tag="VU534_002078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS1380-like element ISSpn5 family transposase"
                     /protein_id="HEU1514591.1"
                     /translation="MNSLPNHHFQNKSFYQLSFDGGHLTQYGGLIFFQELFSQLKLKE
                     RISKYLVTNDQRRYCRYSDSDILVQFLFQLLTGYGTDYACKELSADAYFPKLLEGGQL
                     ASQPTLSRFLSRTDEETVHSLRCLNLELVEFFLQFHQLNQLIVDIDSTHFTTYGKQEG
                     VAYNAHYRAHGYHPLYAFEGKTGYCFNAQLRPGNRYCSEEADSFITPVLERFNQLLFR
                     MDSGFATPKLYDLIEKTGQYYLIKLKKNTVLSRLGDLSLPCPQDEDLTILPHSAYSET
                     LYQAGSWSHKRRVCQFSERKEGNLFYDVISLVTNMTSGTSQDQFQLYRGRGQAENFIK
                     EMKEGFFGDKTDSSTLIKNEVRMMMSCIAYNLYLFLKHLAGGDFQTLTIKRFRHLFLH
                     VVGKCVRTGRKQLLKLSSLYAYSELFSALYSRIRKVNLNLPVPYEPPRRKASLMMH"
BASE COUNT          488 a          359 c          327 g          487 t
ORIGIN      
        1 ctaaaaacca tccagaatcc ttgccttagc ttagatcctg gatggtttct tttttcaccc
       61 aatgggtgtt ttttactaga caaaaaagag tttccccttt atggtataag tgtagaaaaa
      121 aacacaaaaa gaaaggaaac tcacatgaac agtttaccaa atcatcactt ccaaaacaag
      181 tctttttacc aactatcttt cgatggaggt catttaaccc agtatggtgg tcttatcttt
      241 tttcaggaac ttttttccca gttgaaacta aaagagcgga tttctaagta tttagtaacg
      301 aatgaccaac gccgctactg tcgttattcg gattcagata tccttgtcca gttcctcttt
      361 caactgttaa caggttatgg aacggactat gcttgtaaag aattgtcagc tgatgcctac
      421 tttccaaaat tgttggaagg agggcagctt gcttcacagc caaccttatc ccgttttctt
      481 tccagaactg acgaggaaac agtccatagt ttgcgatgcc tcaaccttga attggtcgaa
      541 ttctttttac agtttcacca gctaaaccaa ctcattgtag atatcgattc tacccatttc
      601 acaacttatg gcaagcaaga aggtgttgct tataacgccc actatcgtgc tcatggctat
      661 catcctcttt atgctttcga ggggaagaca ggttattgtt tcaatgccca gcttcgtcct
      721 ggtaatcgtt attgttctga agaggcagac agctttatca cacctgtttt agaacggttt
      781 aatcaacttc tctttcgaat ggatagtggc tttgcgaccc caaaattata cgatttaatt
      841 gaaaaaacag ggcaatacta cctcataaaa ctcaagaaaa atactgttct gagccgtctt
      901 ggagaccttt ccctcccttg cccacaggat gaggacttaa ccatcttgcc ccactccgcc
      961 tactcagaaa ctctctatca agcaggatct tggtcgcaca agcgtcgtgt ctgccagttc
     1021 tctgaacgaa aagaaggaaa cttgttctac gatgttattt ctctcgttac aaatatgacg
     1081 agtggaacaa gccaagacca gtttcagctt tatcgtggac gtggtcaagc cgagaatttc
     1141 atcaaggaga tgaaggaggg attttttggc gataaaacgg atagttcaac cttaatcaaa
     1201 aacgaagttc gtatgatgat gagctgtatc gcctacaatc tctatctttt tctcaaacat
     1261 ctagctggag gtgacttcca aactttaaca atcaaacgct tccgccatct ttttcttcac
     1321 gtggtgggaa aatgtgttcg aacaggacgc aagcagctcc tcaaattgtc tagtctctat
     1381 gcctattccg aattgttttc agcactttat tctaggatta gaaaagtcaa cctgaatctt
     1441 cctgttcctt atgaaccacc tagaagaaaa gcgtcgttaa tgatgcatta aagaacagtc
     1501 gagatgaaaa aatcgtgtga cgcaccaagg gaggagtctg cccttttgag gaaatctagc
     1561 gaggaaaaac gatactggaa cagcagaaag taaaactgac ctcatgagga ggaagaaagt
     1621 ggctcatgag gtcaggggtt ttgtaagtta catctagttg a
//
LOCUS       DAVFER010000091         1617 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1105170250
            SAMEA2167659-rid19724873.denovo.091, whole genome shotgun sequence.
ACCESSION   DAVFER010000091 DAVFER010000000
VERSION     DAVFER010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2167659
            Sequence Read Archive: ERR388902
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1617)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1617)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928716.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928716.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 04:07:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,118
            CDSs (total)                      :: 2,073
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 120
            CDSs (without protein)            :: 120
            Pseudo Genes (ambiguous residues) :: 0 of 120
            Pseudo Genes (frameshifted)       :: 67 of 120
            Pseudo Genes (incomplete)         :: 47 of 120
            Pseudo Genes (internal stop)      :: 34 of 120
            Pseudo Genes (multiple problems)  :: 23 of 120
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1617
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2167659-rid19724873.denovo.091"
                     /strain="1105170250"
                     /db_xref="taxon:1313"
     gene            complement(<1..210)
                     /locus_tag="VU534_002079"
     CDS             complement(<1..210)
                     /locus_tag="VU534_002079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEU1514592.1"
                     /translation="MQRLEVYKNYQHLYDLRIAILLNLSTLYLYNQDKNMCKQICYTL
                     LEDAKNKKSYDRLAICYVRIGICTDD"
     gene            968..1348
                     /locus_tag="VU534_002080"
     CDS             968..1348
                     /locus_tag="VU534_002080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_0115 family bacteriocin-like peptide"
                     /protein_id="HEU1514593.1"
                     /translation="MELVLPNNYVALEQEEMMYLDGGGVGRNWWNSRGSFATVLDVDL
                     AIYSGGATIYSAYAIKKAISANRGAITRTLRSLIIKHVGSAAGHLVNTALNVALTVTG
                     FSLGGAIAYGADWADGSLDGYIFA"
BASE COUNT          514 a          197 c          331 g          575 t
ORIGIN      
        1 atcgtctgta caaatcccaa tacggacata gcagatagca agcctatcgt agcttttctt
       61 attcttggcg tcctccagta aagtgtagca gatttgctta cacatgtttt tatcttgatt
      121 gtatagatag agtgtggaaa ggtttagcag gattgctatt cgcaagtcat ataaatgttg
      181 atagttttta tagacttcta agcgttgcaa gattttctcg gattattgac aaataaacgg
      241 atattctgat agacgattgc cctagcggct tagtgtaaac tttacaaatt tggcttgtaa
      301 tttttttata aaattcactt cagttacttg acagttatta tattttcact tattatatag
      361 ataaaaggat gggataggag tttaaaaatt tgaaagcgct atccataatc ataacgcata
      421 attttctcct tttcgtgaaa aaagttaacg taattttgaa atgagcttaa taagaggtat
      481 gatgtaggta gaaaataaag ataggagaaa aagtatgaat aaaaaaatat tttgtattct
      541 agtatgtatt atatcattga ttagtctagc tataatcttt ccatggggct ggtcgatata
      601 atgtaaggga gcttgagttg ttagtggagg ataaaatgtt aagagtaata gtagttattc
      661 aatctttagt aataatactg cttgctgttg ctttattatt atctcggaaa aactttgatt
      721 cgttaaatgt tgttcttata atgatgatcg tatcacaatt gttgttatta gtatatttga
      781 taaaatcagg gaatcagtga ttagctgtta tttgaattaa gtaaactgtt aagcttcaag
      841 cagtaactgg ttttaaatat ttaaaataag ataaaggaag gaagtctaat ttaggtaact
      901 aaacaaagcc tgcgatcact tgttaggaaa ccatcctaac catgcttaat aaaaaaggag
      961 aaaataaatg gaactcgtat taccaaataa ttatgttgct cttgagcaag aagagatgat
     1021 gtatcttgat gggggtggtg ttggtcgtaa ctggtggaat agtagaggta gttttgcaac
     1081 agttctggat gtagatttgg ccatctatag tggtggtgca acaatttatt ctgcttatgc
     1141 gataaaaaaa gctatctcag ctaatagagg ggctattacg agaacattac gtagtttaat
     1201 aattaaacat gtaggtagtg cagctggcca tttagtcaat actgcactaa acgttgcact
     1261 aactgttact ggattttcac taggtggagc aatcgcatat ggggctgatt gggctgacgg
     1321 tagcttagat ggttatattt ttgcttaaaa tgaaacattt ttttgcagga attggtgaaa
     1381 taaactttgt aagttattta ttgtatatat gtgtaggaat agcccctttt tttcatatat
     1441 atgtcatagg ttcggaactg agttttgtga aaatagtgtt atctattttg ggagttatat
     1501 ttgtaagtat gttaactatt gctcgaattt atcggacttt tctataaaga atagtttgga
     1561 cttgaactgt atctaaaaac agaggttggt agattatcag cctctttctt gtcgttg
//
LOCUS       DAVFER010000092         1455 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1105170250
            SAMEA2167659-rid19724873.denovo.092, whole genome shotgun sequence.
ACCESSION   DAVFER010000092 DAVFER010000000
VERSION     DAVFER010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2167659
            Sequence Read Archive: ERR388902
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1455)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1455)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928716.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928716.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 04:07:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,118
            CDSs (total)                      :: 2,073
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 120
            CDSs (without protein)            :: 120
            Pseudo Genes (ambiguous residues) :: 0 of 120
            Pseudo Genes (frameshifted)       :: 67 of 120
            Pseudo Genes (incomplete)         :: 47 of 120
            Pseudo Genes (internal stop)      :: 34 of 120
            Pseudo Genes (multiple problems)  :: 23 of 120
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1455
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2167659-rid19724873.denovo.092"
                     /strain="1105170250"
                     /db_xref="taxon:1313"
     gene            <1..559
                     /locus_tag="VU534_002081"
     CDS             <1..559
                     /locus_tag="VU534_002081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEU1514594.1"
                     /translation="EVPCEIPESWEWVRLNDITSYIQRGKSPKYSNIPIYPVIAQKCN
                     QWSGFSIDLARFIDPETVHSYQKERLLRDGDLMWNSTGLGTLGRLAIYHENKNPYGWA
                     VADSHVTVIRVLSGVINCHFIYNFLSSPIVQSVIEEKASGSTKQKELLTKTIKEYLIP
                     LPPLPEQSRIVDKIEQFFAHIDALI"
     gene            616..1413
                     /gene="psrA"
                     /locus_tag="VU534_002082"
     CDS             616..1413
                     /gene="psrA"
                     /locus_tag="VU534_002082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000651177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type DNA invertase PsrA"
                     /protein_id="HEU1514595.1"
                     /translation="MKDFELHLKKAGLAENTVRSYLYGVRFFLENYELKMEDLFEYKG
                     YLLDNFKPKTVNLRLQGVNKYLAFIGHDDLKLKFVKVQQKPFLEDVISHADYLFLKRS
                     LKKDGILKWHFVVWFLGATGARVSELIKLKVEHVEIGYFDIYSKGGKIRRLYIPKKLR
                     NSCLSWLESENRRSGYLFLNKFNEPITARGVAQQLKNYADKYKMNPKVIYPHSFRHLF
                     AKNFLAKYNDIALLADLMGHESIETTRIYLRKTATEQQNIVDKIVNW"
BASE COUNT          505 a          208 c          266 g          476 t
ORIGIN      
        1 ggaagtacct tgtgaaatac cagaaagttg ggaatgggtg aggttaaacg atataacctc
       61 ctacattcaa agagggaagt ctccaaaata ttcaaatatt cctatatacc ctgtgattgc
      121 tcagaaatgt aatcaatggt ctggcttttc tattgactta gcaagattta ttgatcccga
      181 aacagttcat agttaccaga aagaaagatt actaagagat ggtgatttaa tgtggaattc
      241 aacaggtcta ggtacgttag gacgattagc tatttaccat gaaaataaaa atccttatgg
      301 ctgggctgtt gcagatagcc atgttacagt tataagagtc ttatcggggg ttattaattg
      361 ccatttcatc tataattttc tttcctctcc tattgttcag tcagttattg aagaaaaagc
      421 gtcgggtagt acaaaacaaa aagaattatt aacgaaaact ataaaagaat atttaatccc
      481 cctcccaccc cttcctgaac aatccagaat cgttgataaa atcgaacaat ttttcgccca
      541 tattgacgca ctaatttagt ataatagttt tacgtgcggt ggaatttcta tcaaacataa
      601 gataggagtt ttacgttgaa agattttgaa ttacatttga agaaagctgg tttagctgaa
      661 aatactgtgc gttcgtacct ttatggtgtt cgatttttct tggagaatta cgaactcaaa
      721 atggaagatt tatttgaata caaaggatat ttattagaca attttaaacc taaaactgtc
      781 aatttgcgac tacaaggagt aaataaatat ctggctttta ttggtcatga tgatttgaaa
      841 ttaaaatttg tcaaagtaca gcaaaaaccg tttttagaag atgtcattag ccatgctgat
      901 tacctttttc ttaaacgtag tttgaaaaaa gatggtattt taaaatggca ttttgtcgtt
      961 tggtttttag gtgcaactgg ggctcgtgta agtgaactta ttaaactaaa agtagagcat
     1021 gtagaaatcg gttattttga catttactca aaaggtggta aaattcgtag actgtacatt
     1081 cctaaaaaat taagaaatag ttgtcttagt tggttagaat cagaaaatcg ccgaagtggt
     1141 tatttatttt tgaataaatt taacgaacca attacagcaa gaggagttgc tcaacagtta
     1201 aaaaattatg ctgataaata caaaatgaat cctaaagtaa tttaccctca ttcttttagg
     1261 catttatttg ctaagaattt tttagcgaag tataatgata ttgccttgct tgcagatttg
     1321 atgggacacg aaagtataga aactactcga atttatctaa ggaaaacagc tactgaacaa
     1381 caaaatattg tagataaaat tgttaattgg taaaaaataa caggtggtca aactgactac
     1441 ctgctatttt tgtga
//
LOCUS       DAVFER010000093         1267 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1105170250
            SAMEA2167659-rid19724873.denovo.093, whole genome shotgun sequence.
ACCESSION   DAVFER010000093 DAVFER010000000
VERSION     DAVFER010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2167659
            Sequence Read Archive: ERR388902
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1267)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1267)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928716.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928716.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 04:07:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,118
            CDSs (total)                      :: 2,073
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 120
            CDSs (without protein)            :: 120
            Pseudo Genes (ambiguous residues) :: 0 of 120
            Pseudo Genes (frameshifted)       :: 67 of 120
            Pseudo Genes (incomplete)         :: 47 of 120
            Pseudo Genes (internal stop)      :: 34 of 120
            Pseudo Genes (multiple problems)  :: 23 of 120
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1267
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2167659-rid19724873.denovo.093"
                     /strain="1105170250"
                     /db_xref="taxon:1313"
     gene            complement(88..237)
                     /gene="blpO"
                     /locus_tag="VU534_002083"
     CDS             complement(88..237)
                     /gene="blpO"
                     /locus_tag="VU534_002083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpO"
                     /protein_id="HEU1514596.1"
                     /translation="MDTKMMSQFAVMDNEMLACVEGGDIDWGRKISCAAGVAYGAIDG
                     CATTV"
     gene            complement(481..684)
                     /gene="blpN"
                     /locus_tag="VU534_002084"
     CDS             complement(481..684)
                     /gene="blpN"
                     /locus_tag="VU534_002084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-peptide bacteriocin subunit BlpN"
                     /protein_id="HEU1514597.1"
                     /translation="MNTYCNINETMLSEVYGGNSGGAAVVAALGCAAGGVKYGRLLGP
                     WGAAIGGIGGAVVCGYLAYTATS"
     gene            complement(700..954)
                     /gene="blpM"
                     /locus_tag="VU534_002085"
     CDS             complement(700..954)
                     /gene="blpM"
                     /locus_tag="VU534_002085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000379879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-peptide bacteriocin subunit BlpM"
                     /protein_id="HEU1514598.1"
                     /translation="MDTKIMEQFHEMDITMLSSIEGGKNNWQTNVLEGGGAAFGGWGL
                     GTAICAASGVGAPFMGACGYIGAKFGVDLWAGVTGATGGF"
     gene            complement(1104..>1267)
                     /locus_tag="VU534_002086"
     CDS             complement(1104..>1267)
                     /locus_tag="VU534_002086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU1514599.1"
                     /translation="CNHALSKERSKVENIFAKVKTFKMFSTTYRSHRKRFGLRMNLSA
                     GIINHELGF"
BASE COUNT          403 a          297 c          164 g          403 t
ORIGIN      
        1 ttgctgcata ggctacacct ccaagtatag ctccacctgc agcaccagtt acacctattc
       61 ctatagcaaa tggtcccaat agaaatgtca aaccgttgtt gcacacccat caattgcgcc
      121 atatgcaacc cctgctgcac aactaatttt tcttccccaa tcaatatctc caccttcaac
      181 gcaagcaagc atttcattat ccataactgc aaattgtgac atcatttttg tatccatata
      241 gtgtatcact tttcagttac ggaacaagtt taatataaaa attatcaaaa aaacataggc
      301 aataaagaga aaaattaatt tatcatagat tagaaataat atgacaaaac aattcaatga
      361 tgttaattca atagtctttt gttttttatc ggagatactt atggatagat aaataagata
      421 ggtttgaaaa gcgaagagaa taataaagaa tatagccttc ataaaattta gctttcattt
      481 ttatgatgta gcggtatagg ctaaatatcc acaaaccact gctcctccaa ttcctcctat
      541 tgcagcgccc catggtccta gaagtctccc atatttcact ccacccgctg cacaacctaa
      601 agcagcaact acagctgctc ctccggaatt acctccataa acctcactca gcattgtttc
      661 atttatatta caataagtat tcatacaagt ctccttttat taaaatccac ccgttgcccc
      721 tgttactcct gcccaaagat ccacaccaaa tttagctcct atgtatccac atgctcccat
      781 aaatggtgct ccaacaccac tcgcagcaca aatagctgtc cctagccccc agccaccaaa
      841 agcagcacca ccaccttcta agacattagt ttgccaatta ttcttgcctc cttcaatact
      901 agataacata gttatatcca tttcatgaaa ttgttccata atttttgtat ccatgacaaa
      961 tactcttttt tatttttaat ttttgtcttg ttgtaacttt gacaagttta gtatatcatc
     1021 gttttttaaa atttttcatc cagattttga atagtcatcg aaacgtcttg aattgcaaaa
     1081 attacattag acttcctgca aaactagaat cctagttcat gattgataat accagcactc
     1141 aaattcattc gtaatccgaa gcgtttacga tgacttcgat aggttgttga aaacatttta
     1201 aacgttttta ctttggcaaa gatgttctca accttgcttc tctccttaga tagcgcatgg
     1261 ttacagg
//
LOCUS       DAVFER010000094         1139 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1105170250
            SAMEA2167659-rid19724873.denovo.094, whole genome shotgun sequence.
ACCESSION   DAVFER010000094 DAVFER010000000
VERSION     DAVFER010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2167659
            Sequence Read Archive: ERR388902
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1139)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1139)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928716.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928716.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 04:07:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,118
            CDSs (total)                      :: 2,073
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 120
            CDSs (without protein)            :: 120
            Pseudo Genes (ambiguous residues) :: 0 of 120
            Pseudo Genes (frameshifted)       :: 67 of 120
            Pseudo Genes (incomplete)         :: 47 of 120
            Pseudo Genes (internal stop)      :: 34 of 120
            Pseudo Genes (multiple problems)  :: 23 of 120
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1139
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2167659-rid19724873.denovo.094"
                     /strain="1105170250"
                     /db_xref="taxon:1313"
     gene            complement(1..232)
                     /locus_tag="VU534_002087"
                     /pseudo
     CDS             complement(1..232)
                     /locus_tag="VU534_002087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            complement(266..>1139)
                     /locus_tag="VU534_002088"
     CDS             complement(266..>1139)
                     /locus_tag="VU534_002088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HEU1514600.1"
                     /translation="KRERRKTEIIQELMTEFSLDILLKAIKLARLTYYYHLKQLDKPD
                     KDQELKAEIQSIFIEHKGNYAYRRIYLELRNRGYLVNHKRVQGLIKVLNLQAKMRQKR
                     KYSSHKGDVGKKAENLIQGQFEGSKTMEKCYTDVTEFAIPASTQKLYLSPVLDGFNSE
                     IIAFNLSCSPNLEQVQTMLEQAFKEKHYENTILHSDQGWQYQHDSYHRFLESKGIQAS
                     MSRKGNSQDNGRMESFFGILKSEMFYGYEKTFKSLNQLEQAIIDYIDYYNNKKIKIKL
                     KGLSPVQYRTKSFG"
BASE COUNT          321 a          220 c          193 g          405 t
ORIGIN      
        1 accagctatt aagaaaaatg attcgcctgt atgggcatca acagctccat aacaatagcg
       61 aaattctcgt atatagtgac tatggacatg tggacctact cctattggag accaacaaga
      121 tcccagttta ctgattctac cgaaaccagc ctcatcttgg tacatcacca gcctcatctt
      181 ggtacatcaa gcgaacctta tgaaaaggtc tactggtttt aaagcgcttt cttgtgtact
      241 gcccccaaac agttagacaa ataatttatc caaaggattt agttctgtac tgcacaggac
      301 taagtccttt tagttttatc ttaattttct tattgttgta ataatcaata tagtctataa
      361 tggcttgttc caattggtta agtgatttaa atgttttctc atagccataa aacatttcgg
      421 attttaaaat gccaaagaaa gattccatcc taccgttgtc ttggctgttg cccttacgtg
      481 acatggatgc ttgaattccc ttactctcta ggaaccgatg ataagaatcg tgttgatatt
      541 gccagccttg gtcactatgg agaatcgtat tctcgtagtg cttctctttg aatgcctgtt
      601 ccaacattgt ttgtacttgt tctaaattag gcgaacaaga aagattaaaa gcaataattt
      661 cactgttaaa gccatctaaa actggtgata agtaaagctt ttgagtactt gctggaatgg
      721 caaattctgt cacatctgtg tagcactttt ccattgtttt agagccttca aattgtcctt
      781 gaatgagatt ctctgccttc ttgccaacgt ctcctttatg agaagaatat tttcgtttct
      841 gtcgcatttt agcttgtaaa ttgagtactt ttatcaagcc ttgaactctt ttatgattta
      901 ccagataacc acgatttctt agttctaaat aaatccgacg ataagcataa tttcccttgt
      961 gttcgataaa aatggattga atttcagctt taagctcttg gtccttatct ggtttatcta
     1021 gctgtttcaa gtgatagtag taggtcaaac gagctagttt aatggctttt agaagaatat
     1081 ctaacgaaaa ctcagtcatt aattcttgaa taatttctgt ctttcttctt tctcttttt
//
LOCUS       DAVFER010000095         1044 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1105170250
            SAMEA2167659-rid19724873.denovo.095, whole genome shotgun sequence.
ACCESSION   DAVFER010000095 DAVFER010000000
VERSION     DAVFER010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2167659
            Sequence Read Archive: ERR388902
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1044)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1044)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928716.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928716.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 04:07:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,118
            CDSs (total)                      :: 2,073
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 120
            CDSs (without protein)            :: 120
            Pseudo Genes (ambiguous residues) :: 0 of 120
            Pseudo Genes (frameshifted)       :: 67 of 120
            Pseudo Genes (incomplete)         :: 47 of 120
            Pseudo Genes (internal stop)      :: 34 of 120
            Pseudo Genes (multiple problems)  :: 23 of 120
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1044
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2167659-rid19724873.denovo.095"
                     /strain="1105170250"
                     /db_xref="taxon:1313"
     gene            <1..550
                     /locus_tag="VU534_002089"
     CDS             <1..550
                     /locus_tag="VU534_002089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001220748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEU1514601.1"
                     /translation="ETTSYPIYEIPEAWRYIKFASLVNFRIGKTPPRSEATFWGTEIP
                     WVSISDMPISGYVTNARESISKLALKSKKIDISPKGTLLMSFKLSIGKVAILDIPATH
                     NEAIISIFPYANKENIIRDYLMIFLPLISTLGDSKDAIKGKTLNSTSISELLIPISNH
                     EEMKRIIFKVDLLFQKVSQLFE"
     gene            complement(504..1043)
                     /locus_tag="VU534_002090"
     CDS             complement(504..1043)
                     /locus_tag="VU534_002090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001104691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEU1514602.1"
                     /translation="MNWVVIKIKDIFSINTGLSYKKGDLSINNKGVRIIRGGNIKPLE
                     FSLLDNDYYIDTQFISSEQVYLKHNQLITPVSTSLEHIGKFARIDKDYDGVVAGGFIF
                     QLTPFESSEIISKFLLFNLSSPLFYKQLKAITKLSGQALYNIPKTTLSELLIPLAPFE
                     EQELITQKVEKLFEKVNQL"
BASE COUNT          373 a          166 c          151 g          354 t
ORIGIN      
        1 cgaaacaacc tcttatccta tatatgaaat cccagaagca tggagatata ttaaatttgc
       61 tagcctagtt aacttcagaa taggaaaaac tcctccacgc agtgaagcta ctttttgggg
      121 aactgaaata ccttgggtat ctatatcaga tatgcctata tctggttatg taactaatgc
      181 gagagaatct atttctaaat tagcattaaa atcaaagaaa atagacattt cacctaaagg
      241 aactttatta atgagtttta aattatctat tggaaaagtt gccatattgg atattcctgc
      301 cactcataat gaagccatta tatcgatatt cccctatgct aataaagaaa atattatcag
      361 agattactta atgatatttt tgccacttat ctctacttta ggtgattcaa aagatgctat
      421 caaagggaaa acattaaata gtaccagtat ctccgaatta ttaatcccta tttctaatca
      481 tgaagagatg aaaagaatca ttttcaaagt tgatttactt tttcaaaaag tttctcaact
      541 ttttgagtaa taagttcctg ttcctcaaaa ggagctaacg gaattaatag ctcgctcagt
      601 gtagttttag gaatattata taaagcttga cctgatagtt tagttattgc tttcaattgt
      661 ttataaaata acggagagga caagttaaat aatagaaatt ttgaaataat ctctgaactt
      721 tcgaatggtg ttaattggaa aataaatcca ccagccacaa caccatcata gtctttatcg
      781 attcttgcaa actttccaat atgttctaaa gaggttgata caggtgttat tagctgatta
      841 tgttttaaat aaacttgctc agaggagatg aattgtgtat caatgtagta atcattatcc
      901 aacagagaaa attctaaagg cttaatatta ccaccacgta taattctaac acctttatta
      961 ttaatgctta aatcgccctt cttgtaagaa agacctgtat ttattgaaaa aatatctttt
     1021 atttttataa caacccaatt cata
//
LOCUS       DAVFER010000096          954 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1105170250
            SAMEA2167659-rid19724873.denovo.096, whole genome shotgun sequence.
ACCESSION   DAVFER010000096 DAVFER010000000
VERSION     DAVFER010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2167659
            Sequence Read Archive: ERR388902
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 954)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 954)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928716.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928716.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 04:07:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,118
            CDSs (total)                      :: 2,073
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 120
            CDSs (without protein)            :: 120
            Pseudo Genes (ambiguous residues) :: 0 of 120
            Pseudo Genes (frameshifted)       :: 67 of 120
            Pseudo Genes (incomplete)         :: 47 of 120
            Pseudo Genes (internal stop)      :: 34 of 120
            Pseudo Genes (multiple problems)  :: 23 of 120
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..954
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2167659-rid19724873.denovo.096"
                     /strain="1105170250"
                     /db_xref="taxon:1313"
     gene            complement(<1..172)
                     /locus_tag="VU534_002091"
     CDS             complement(<1..172)
                     /locus_tag="VU534_002091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU1514603.1"
                     /translation="MVNCEPLEAYRQLEEAELVGCWAHVRRKFFEATPKQADKSSLGA
                     KGLAYCDQLFSLE"
     gene            complement(245..472)
                     /locus_tag="VU534_002092"
     CDS             complement(245..472)
                     /locus_tag="VU534_002092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001827253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU1514604.1"
                     /translation="MRERLLTQPLLHADETSYRVLESHSHLTYYWTFLSGKVENQAIT
                     LYHHDQSRSGSVVQEFLGDYSGYVHCDMLRQ"
     gene            500..685
                     /locus_tag="VU534_002093"
                     /pseudo
     CDS             500..685
                     /locus_tag="VU534_002093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            780..954
                     /locus_tag="VU534_002094"
                     /pseudo
     CDS             780..954
                     /locus_tag="VU534_002094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000433508.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT          306 a          204 c          170 g          274 t
ORIGIN      
        1 tttccaagga aaataactga tcacaataag ctaaaccttt agctcctaag gatgatttat
       61 ctgcttgctt gggggtcgct tcaaaaaatt tccttctcac atgcgcccaa catccaacaa
      121 gttcagcttc ttccagttga cgataagctt ctagcggttc gcagtttacc aagcttagcg
      181 tcgccttgct cctaaacctt ggactgctat cgcataggca gaactagagg actaaagtcc
      241 taagttactg ccgcaacata tcacaatgaa catagccaga ataatctcct aggaattctt
      301 gtactaccga accactccga ctctgatcat gatggtacag cgtgattgct tgattctcaa
      361 ctttcccaga caaaaaggtc caatagtagg tcagatggct atgactctct agaacccgat
      421 aagaagtttc atccgcatga agtaagggct gagtcaatag tctctctcgc aagaggttat
      481 aaaggggctt taggaatagg agctttcaca agcttatcca gatgattatc ttttactcgt
      541 tatggacaat gctatatggc ataaatcaag taccttaaag attccgacta atattggttt
      601 tgcatttatt cctccataca caccagagat gaaccccatt gaacaagtgt ggaaagagat
      661 tcgtaaacgt ggatttatag taaaatgaaa taataacagg acaaatcatt caggacagtc
      721 aaatcgattt ctaacaatgt tttagaagca gaggtgtact attctagttt caatctacta
      781 tagataaact tttgagctat tcagaagact tgaaacacca ctataatctc tatcaactct
      841 tgctttttca ctttcagaat aaggagcctg acaaattttt cggactcatt gaggacaatc
      901 tgaatcaagt tcatcctcta aaaccttcct caaagataaa gagaagattg tcaa
//
LOCUS       DAVFER010000097          905 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1105170250
            SAMEA2167659-rid19724873.denovo.097, whole genome shotgun sequence.
ACCESSION   DAVFER010000097 DAVFER010000000
VERSION     DAVFER010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2167659
            Sequence Read Archive: ERR388902
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 905)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 905)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928716.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928716.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 04:07:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,118
            CDSs (total)                      :: 2,073
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 120
            CDSs (without protein)            :: 120
            Pseudo Genes (ambiguous residues) :: 0 of 120
            Pseudo Genes (frameshifted)       :: 67 of 120
            Pseudo Genes (incomplete)         :: 47 of 120
            Pseudo Genes (internal stop)      :: 34 of 120
            Pseudo Genes (multiple problems)  :: 23 of 120
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..905
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2167659-rid19724873.denovo.097"
                     /strain="1105170250"
                     /db_xref="taxon:1313"
     gene            146..310
                     /locus_tag="VU534_002095"
     CDS             146..310
                     /locus_tag="VU534_002095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1514605.1"
                     /translation="MKKKILIIFVLYLIMSIFLYPLRESAWYQLFYTIAYVIAVMIYF
                     AINKKKGEKK"
     gene            307..711
                     /locus_tag="VU534_002096"
     CDS             307..711
                     /locus_tag="VU534_002096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000846948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="immunity protein"
                     /protein_id="HEU1514606.1"
                     /translation="MKTFLAKKRNIFLARLFLGQLPLLVSTYLFLSRQFLNFSVVFQF
                     LLVVINLASILVTVYLTREMRIREFEDDDLVSPRTNQLMFIGLTGFMSIICLYRGITA
                     GESYQQIIAYIGAVLCLIIMLLLMWGLKYYKK"
BASE COUNT          268 a          139 c          159 g          339 t
ORIGIN      
        1 atgcttgctt ttttaatttt tacaattcaa gaggttttga tgaccattta tgatttgagt
       61 gatccaaggt caaaataagt gctatactag cagtgtaaat gttcttgctc aactaagata
      121 aatcgcacat ttaggaggaa atcttatgaa gaaaaaaata ctgattattt tcgttctgta
      181 tctaatcatg tccatctttc tatatccgct tagggagagt gcttggtatc agctatttta
      241 taccatagcc tatgtgattg cagttatgat ctattttgct atcaataaaa agaaaggaga
      301 aaagaaatga aaacttttct tgctaaaaaa cggaacatct tccttgcgag attgttctta
      361 ggtcagttgc ccttgcttgt ttctacttat ctatttctat ctcgtcagtt tttaaatttt
      421 tccgtagttt tccaatttct tttagtagtt attaacttgg cttctatttt ggttactgtt
      481 tatctcacta gggaaatgag gataagagag tttgaagatg atgatttggt tagtcctaga
      541 accaatcaac ttatgttcat cggcttgaca ggttttatgt ctattatttg tttgtataga
      601 ggtatcacag caggagaatc ctaccaacaa ataatcgctt atattggcgc tgttctctgc
      661 ttaatcatca tgcttctgct catgtggggc ttgaagtatt ataaaaagta gagcttaatg
      721 aagtataaaa gaaaagggta agtgtttttg caatacttac ccttttataa tagattccct
      781 gcgaaacaaa atatggtata gtatagtaga ttgaaactag aatagtacgc ctctacttct
      841 aaaacattgt tagaaatcga tttgactgtc ctgatcgatt tatcctgttc ttatttcatt
      901 ttact
//
LOCUS       DAVFER010000098          897 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1105170250
            SAMEA2167659-rid19724873.denovo.098, whole genome shotgun sequence.
ACCESSION   DAVFER010000098 DAVFER010000000
VERSION     DAVFER010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2167659
            Sequence Read Archive: ERR388902
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 897)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 897)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928716.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928716.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 04:07:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,118
            CDSs (total)                      :: 2,073
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 120
            CDSs (without protein)            :: 120
            Pseudo Genes (ambiguous residues) :: 0 of 120
            Pseudo Genes (frameshifted)       :: 67 of 120
            Pseudo Genes (incomplete)         :: 47 of 120
            Pseudo Genes (internal stop)      :: 34 of 120
            Pseudo Genes (multiple problems)  :: 23 of 120
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..897
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2167659-rid19724873.denovo.098"
                     /strain="1105170250"
                     /db_xref="taxon:1313"
     gene            complement(<1..221)
                     /locus_tag="VU534_002097"
     CDS             complement(<1..221)
                     /locus_tag="VU534_002097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HEU1514607.1"
                     /translation="MRDANRGGCSQSCRWKYDLYDMPFGKERKSLQGEIPEEFSMSAV
                     DMSMIDHISDMIENGVDSLKIEGRMESIH"
     gene            complement(470..781)
                     /locus_tag="VU534_002098"
     CDS             complement(470..781)
                     /locus_tag="VU534_002098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1514608.1"
                     /translation="MIEAQGFLVDKQTRCIHYHSKLDIIALQCYDCKKYYACYRCHDS
                     LEHHPFEPYPLSLIQDKPILCGVCLKLLTYKQYKESLSCPFCFSRFNPGCQNHKERYF
                     K"
     gene            complement(796..>897)
                     /locus_tag="VU534_002099"
     CDS             complement(796..>897)
                     /locus_tag="VU534_002099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HEU1514609.1"
                     /translation="VPQPVQSGDMVRALKEGLINLYKEDGTSVTVRA"
BASE COUNT          285 a          177 c          144 g          291 t
ORIGIN      
        1 tagtgaatag actccatacg tccttcgatt tttagactgt ccacaccatt ttcaatcata
       61 tctgagatat ggtcaatcat agacatatca acggctgaca ttgaaaattc ttctggaatc
      121 tcaccctgca aactcttacg ttctttccca aatggcatat cgtaaaggtc gtacttccaa
      181 cggcatgact gagaacatcc accacggttg gcatcacgca tactctagac ggattgtttt
      241 gacaattcta accttttaga ctttgcataa taactattaa acagtcgaaa attaacccag
      301 ttttaacaag tagtcaaaat accagataaa ggaaaaaagt ctttaaaatc ttaaaaacgc
      361 atagtatcag gtattgaaca atcttgatat tatgcgtttt attgtgggaa gatttacttc
      421 attttctctt gaaattgagt tttctcctac ttcaaaacta gatgatttgc tatttaaaat
      481 agcgttcctt atgattttgg caacctggat taaagcgaga aaaacaaaag gggcaactta
      541 agctttcttt atattgctta tatgttagta gttttagaca aacaccacat aaaataggct
      601 tatcctgtat caaagataag ggatacggct caaaagggtg atgttctaat gaatcatgac
      661 accgataaca agcataatac tttttacaat catagcattg taaagcaata atatccagct
      721 tgctatggta atgaatgcat cttgtttgct tatccactaa gaaaccctgt gcctctatca
      781 tttccttttc ctttcttaag ctcgaactgt gacgctggtt ccatcttcct tataaagatt
      841 gatgagtcct tcttttaatg cacgaaccat atctcctgat tgaacgggtt gaggcac
//
LOCUS       DAVFER010000099          761 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1105170250
            SAMEA2167659-rid19724873.denovo.099, whole genome shotgun sequence.
ACCESSION   DAVFER010000099 DAVFER010000000
VERSION     DAVFER010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2167659
            Sequence Read Archive: ERR388902
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 761)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 761)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928716.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928716.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 04:07:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,118
            CDSs (total)                      :: 2,073
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 120
            CDSs (without protein)            :: 120
            Pseudo Genes (ambiguous residues) :: 0 of 120
            Pseudo Genes (frameshifted)       :: 67 of 120
            Pseudo Genes (incomplete)         :: 47 of 120
            Pseudo Genes (internal stop)      :: 34 of 120
            Pseudo Genes (multiple problems)  :: 23 of 120
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..761
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2167659-rid19724873.denovo.099"
                     /strain="1105170250"
                     /db_xref="taxon:1313"
     gene            complement(498..725)
                     /locus_tag="VU534_002100"
     CDS             complement(498..725)
                     /locus_tag="VU534_002100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000335278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEU1514610.1"
                     /translation="MSLSGGQKQRLAIASVMCKNSPFVFFDEPSSGMDYSNMIKISEL
                     INKYKTMDKIIFIVSHDIEFLNEVADEIFEL"
BASE COUNT          273 a          122 c           92 g          274 t
ORIGIN      
        1 ctatttaccg tggactaaag ttgtacaaga aaagtgcaaa taagaaatct ccagattagg
       61 aactatccgt gagttctcta gtctggagat ttttcaatag acttcgttat tggacggtta
      121 caatttatta tatgaaaatc ccatatcatt ctccaattct atattttacc tttctaaatg
      181 tatagattaa ctacctaatt atagcatata acgcagattc ctttcaatcg tatgatttac
      241 tgcattaaat taagtaaaaa aataaaggca gtccgaagac tgccgatatt tatctctcat
      301 ctctttaatt atggtaagta aataaataat ttccctaaag atatggaaat tattaatact
      361 ataaatacat attataaagt ttataaatac tgtaaaaatc ctgaagttaa ttttctaata
      421 aatatcaata tgtgttagta tcttttaaat ttttagacaa tttactagtt ctatagacat
      481 gtttaacaga ctctatttta caattcaaaa atttcatctg ccacttcatt taaaaattct
      541 atatcatggg aaacaataaa aattatttta tccatggttt tatacttatt aatcagttca
      601 gatattttta tcatattgga ataatccata ccacttgaag gttcgtcaaa aaagacaaat
      661 ggagaattct tgcacataac agatgctatt gcaagccttt gcttttgccc tcctgataaa
      721 ctcatcggat gcctttcaat aaattcgtcc aggcataaat c
//
LOCUS       DAVFER010000100          723 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1105170250
            SAMEA2167659-rid19724873.denovo.100, whole genome shotgun sequence.
ACCESSION   DAVFER010000100 DAVFER010000000
VERSION     DAVFER010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2167659
            Sequence Read Archive: ERR388902
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 723)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 723)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928716.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928716.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 04:07:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,118
            CDSs (total)                      :: 2,073
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 120
            CDSs (without protein)            :: 120
            Pseudo Genes (ambiguous residues) :: 0 of 120
            Pseudo Genes (frameshifted)       :: 67 of 120
            Pseudo Genes (incomplete)         :: 47 of 120
            Pseudo Genes (internal stop)      :: 34 of 120
            Pseudo Genes (multiple problems)  :: 23 of 120
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..723
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2167659-rid19724873.denovo.100"
                     /strain="1105170250"
                     /db_xref="taxon:1313"
     gene            <1..>723
                     /locus_tag="VU534_002101"
     CDS             <1..>723
                     /locus_tag="VU534_002101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HEU1514611.1"
                     /translation="SKIPYLETTGMPTRILLRKRRFKCYHCSKMMVAETSIVKKNHQI
                     PRIINQKIAQKLIEKISMTDIAHQLSISTSTVIRKLNDFHFKHDFSCLPEIMSWDEYA
                     FTKGKMSFIAQDFNNLNIITVLEGRTQAIIRNHFLKYDRAVRCRVKIITMDMFSPYYD
                     LARQLFPCAKIVLDRFHIVQHLSRAMSRVRVQIMNQLDRKSHEYKAIKRYWKLIQQDS
                     RKLSDKHFYRPTFRMHLTNKEIL"
BASE COUNT          224 a          147 c          119 g          233 t
ORIGIN      
        1 tctaaaattc cttatcttga aacgactggt atgcctacta gaattctcct tagaaagcgt
       61 cgattcaagt gctatcactg ttcaaaaatg atggtcgctg aaacttctat cgtcaagaag
      121 aatcaccaaa tccctcgtat catcaaccaa aaaattgctc aaaagttaat tgaaaagatt
      181 tctatgactg atattgccca tcagctttcc atctcaactt caactgttat tcgtaagctc
      241 aatgactttc actttaaaca tgatttttct tgtcttcctg agattatgtc ttgggatgag
      301 tatgctttta caaagggaaa gatgagcttc attgcgcaag attttaacaa tctcaatatc
      361 atcactgttc ttgagggaag aacacaagct atcattcgaa atcactttct taaatatgat
      421 agagccgtcc gatgtcgcgt caaaattatt actatggata tgtttagtcc ttactatgac
      481 ttagctagac aacttttccc atgtgctaaa atcgtgttgg atcgctttca cattgtacaa
      541 catcttagcc gtgctatgag tcgtgtgcgt gttcaaatca tgaatcaatt ggatcgaaag
      601 tctcatgaat acaaggctat caagcgctac tggaagctca tacaacagga tagtcgtaaa
      661 ctcagcgata aacattttta tcgccctact tttcgtatgc atttaaccaa taaagagatt
      721 tta
//
LOCUS       DAVFER010000101          697 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1105170250
            SAMEA2167659-rid19724873.denovo.101, whole genome shotgun sequence.
ACCESSION   DAVFER010000101 DAVFER010000000
VERSION     DAVFER010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2167659
            Sequence Read Archive: ERR388902
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 697)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 697)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928716.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928716.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 04:07:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,118
            CDSs (total)                      :: 2,073
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 120
            CDSs (without protein)            :: 120
            Pseudo Genes (ambiguous residues) :: 0 of 120
            Pseudo Genes (frameshifted)       :: 67 of 120
            Pseudo Genes (incomplete)         :: 47 of 120
            Pseudo Genes (internal stop)      :: 34 of 120
            Pseudo Genes (multiple problems)  :: 23 of 120
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..697
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2167659-rid19724873.denovo.101"
                     /strain="1105170250"
                     /db_xref="taxon:1313"
     gene            complement(112..585)
                     /gene="tnpA"
                     /locus_tag="VU534_002102"
     CDS             complement(112..585)
                     /gene="tnpA"
                     /locus_tag="VU534_002102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001206386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605-like element ISSpn6 family
                     transposase"
                     /protein_id="HEU1514612.1"
                     /translation="MREDNQSLSHTTWNCKYHIVFAPKYRRQIIYGRYKASIGRIIRD
                     LCERKGVIIHEANACSDHIHMLISIPPKLSVSSFMGYLKGKSSLMIFDKHANLKYKYG
                     NRKFWCRGYYVDTVGRNQKVIAEYIQNQLQEDRVADQLTLFESVDPFTGEINKRK"
BASE COUNT          190 a          159 c          125 g          223 t
ORIGIN      
        1 actggtggtt tgttctgcgg ctataagccg cttctaccgg ccagggccaa aggcccaccg
       61 aaatagcttc ctcgcgcacc actttcccga gcaggtgcta aagcacctta gttacttcct
      121 cttatttatt tcgccagtaa acggatctac tgactcgaat aacgtgagct ggtctgctac
      181 tctgtcttct tgtaattgat tctgaatata ttcagctatc actttctgat tacggcctac
      241 cgtatctaca taatagcctc tacaccaaaa cttgcgattg ccatatttgt attttaaatt
      301 cgcatgctta tcaaaaatca tcaaactgct cttgcccttt aaatagccca taaaggacga
      361 aacactaagt ttcggaggaa tactgataag catgtgaata tggtctgaac aagcattcgc
      421 ttcatggatt attacaccct tacgctcaca taagtcacgt atgattcttc cgatactagc
      481 tttgtatctg ccataaatga tttgacgacg atatttgggt gcaaaaacaa tatgatattt
      541 acaattccat gtggtatgtg ataaactttg attatcctct ctcatgaggt acctcctgta
      601 tgatatgttg tagtggcgga gaaaccactt ctatcttatc attttaggag gttctttttg
      661 ttaccacgct aaaagctcta tggaaccact agcatag
//
LOCUS       DAVFER010000102          692 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1105170250
            SAMEA2167659-rid19724873.denovo.102, whole genome shotgun sequence.
ACCESSION   DAVFER010000102 DAVFER010000000
VERSION     DAVFER010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2167659
            Sequence Read Archive: ERR388902
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 692)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 692)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928716.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928716.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 04:07:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,118
            CDSs (total)                      :: 2,073
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 120
            CDSs (without protein)            :: 120
            Pseudo Genes (ambiguous residues) :: 0 of 120
            Pseudo Genes (frameshifted)       :: 67 of 120
            Pseudo Genes (incomplete)         :: 47 of 120
            Pseudo Genes (internal stop)      :: 34 of 120
            Pseudo Genes (multiple problems)  :: 23 of 120
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..692
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2167659-rid19724873.denovo.102"
                     /strain="1105170250"
                     /db_xref="taxon:1313"
     gene            complement(74..147)
                     /locus_tag="VU534_002103"
     tRNA            complement(74..147)
                     /locus_tag="VU534_002103"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(111..113),aa:Arg,seq:acg)
     gene            complement(157..242)
                     /locus_tag="VU534_002104"
     tRNA            complement(157..242)
                     /locus_tag="VU534_002104"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(206..208),aa:Leu,seq:taa)
     gene            complement(250..321)
                     /locus_tag="VU534_002105"
     tRNA            complement(250..321)
                     /locus_tag="VU534_002105"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(287..289),aa:Gly,seq:gcc)
     gene            complement(344..416)
                     /locus_tag="VU534_002106"
     tRNA            complement(344..416)
                     /locus_tag="VU534_002106"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(381..383),aa:Thr,seq:tgt)
     gene            complement(435..516)
                     /locus_tag="VU534_002107"
     tRNA            complement(435..516)
                     /locus_tag="VU534_002107"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(480..482),aa:Leu,seq:tag)
     gene            complement(522..594)
                     /locus_tag="VU534_002108"
     tRNA            complement(522..594)
                     /locus_tag="VU534_002108"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(559..561),aa:Lys,seq:ttt)
     gene            complement(619..691)
                     /locus_tag="VU534_002109"
     tRNA            complement(619..691)
                     /locus_tag="VU534_002109"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(656..658),aa:Asp,seq:gtc)
BASE COUNT          179 a          205 c          149 g          159 t
ORIGIN      
        1 cgaacctgcg acaccttggt cccaaaccaa gtactctacc aagctgagct acttcccgag
       61 ttaaatagaa aaatgcaccc tagaggagtc gaacctctaa ccgcctgatt cgtagtcagg
      121 tactctatcc agttgagcta agggtgctcc atattatgcc gaggaccgga atcgaaccgg
      181 tacgatcgtt accaatcgca ggattttaag tcctgtgcgt ctgccagttc cgccaccccg
      241 gcctctctaa gcgaacgacg ggattcgaac ccgcgacccc caccttggca aggtggtgtt
      301 ctaccactga actacgttcg cactgttttc ttctatctaa aaatgccggc tacatgactt
      361 gaacacgcga ccctctgatt acaaatcaga tgctctacca actgagctaa gccggctcat
      421 ttgttatatc ttaatgcggg ttaagggact tgaaccccca cgccgttaag cgccagatcc
      481 taaatctggt gcgtctgcca attccgccaa acccgcatat atgacccgta ctgggctcga
      541 accagtgacc cattgattaa aagtcaattg ctctaccaac tgagctaacg agtctaaaat
      601 aacttgcgtt accttaaacg gtcccgacgg gaatcgaacc cgcgatcttc gccgtgacag
      661 ggcgacgtga taaccgctac actacgggac ct
//
LOCUS       DAVFER010000103          618 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1105170250
            SAMEA2167659-rid19724873.denovo.103, whole genome shotgun sequence.
ACCESSION   DAVFER010000103 DAVFER010000000
VERSION     DAVFER010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2167659
            Sequence Read Archive: ERR388902
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 618)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 618)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928716.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928716.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 04:07:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,118
            CDSs (total)                      :: 2,073
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 120
            CDSs (without protein)            :: 120
            Pseudo Genes (ambiguous residues) :: 0 of 120
            Pseudo Genes (frameshifted)       :: 67 of 120
            Pseudo Genes (incomplete)         :: 47 of 120
            Pseudo Genes (internal stop)      :: 34 of 120
            Pseudo Genes (multiple problems)  :: 23 of 120
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..618
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2167659-rid19724873.denovo.103"
                     /strain="1105170250"
                     /db_xref="taxon:1313"
     gene            81..560
                     /locus_tag="VU534_002110"
     CDS             81..560
                     /locus_tag="VU534_002110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HEU1514613.1"
                     /translation="MIKELYEEVQGTVYKCRNEYYLHLWELSDWEQEGMLCLHELISR
                     EEGLVDDIPRLRKYFKTKFRNRILDYIRKQESQKRRYDKEPYEEVGEISHRISEGGLW
                     LDDYYLFHETLRDYRNKQSKEKQEELERVLSNERFRGRQRVLRDLRIVFKEFTIRTH"
BASE COUNT          240 a           76 c          145 g          157 t
ORIGIN      
        1 gagctaaagg gaacagaatg gagaaaatgg aacaaatgtg ttttctaatc tgttagactg
       61 tatctagaaa ggggaaaatt atgattaaag aattgtatga agaagtccaa gggactgtgt
      121 ataagtgtag aaatgaatat taccttcatt tatgggaatt gtcggattgg gagcaagaag
      181 gcatgctctg cttacatgaa ttgattagta gagaagaagg actggtagac gatattccac
      241 gtttaaggaa atatttcaag accaagtttc gaaatcgaat tttagactat atccgtaaac
      301 aggaaagtca gaagcgtaga tacgataaag aaccctatga agaagtgggt gagatcagtc
      361 atcgtataag tgaggggggt ctctggctag atgattatta tctctttcat gaaacactaa
      421 gagattatag aaacaaacaa agtaaagaga aacaagaaga actagaacgc gtcttaagca
      481 atgaacgatt tcgagggcgt caaagagtat taagagactt acgcattgtg tttaaggagt
      541 ttactatccg tacccactag taagtcatgc aaaaaaaatg aaaaaaatta gaaaaagtag
      601 ttgacaaagt ttgaaaag
//
LOCUS       DAVFER010000104          578 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1105170250
            SAMEA2167659-rid19724873.denovo.104, whole genome shotgun sequence.
ACCESSION   DAVFER010000104 DAVFER010000000
VERSION     DAVFER010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2167659
            Sequence Read Archive: ERR388902
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 578)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 578)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928716.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928716.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 04:07:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,118
            CDSs (total)                      :: 2,073
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 120
            CDSs (without protein)            :: 120
            Pseudo Genes (ambiguous residues) :: 0 of 120
            Pseudo Genes (frameshifted)       :: 67 of 120
            Pseudo Genes (incomplete)         :: 47 of 120
            Pseudo Genes (internal stop)      :: 34 of 120
            Pseudo Genes (multiple problems)  :: 23 of 120
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..578
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2167659-rid19724873.denovo.104"
                     /strain="1105170250"
                     /db_xref="taxon:1313"
     gene            1..578
                     /locus_tag="VU534_002111"
                     /pseudo
     CDS             1..578
                     /locus_tag="VU534_002111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; incomplete; missing N-terminus and
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="IS630-like element ISSpn2 family transposase"
BASE COUNT          175 a          107 c          129 g          167 t
ORIGIN      
        1 aaacacgtgg tggtcgtaac catgcatata tgacagttga ggaaaagaaa gtctttcttg
       61 cccgccattt gaaggctgca gaggcaggag aatttgttac aattgatgcc ttatttcagg
      121 cttataaaaa ggagttaggt cgttcctaca cacgtgatgc cttctatcaa ctgttgaagt
      181 gccatggttg gcgaaatatt atgccacgtc cagaacatcc taagaaagca gacgctcaaa
      241 ccattgtcgc gtctaaaaat aaaatctcaa ttcaagaaga aaagaaagcg ctttaaaacc
      301 agtagacgtt ttcgtaaggt tcgcttgatg taccaagatg aggctggttt cggtagaatc
      361 agtaaactgg gatcttgttg ggctccaata ggagtaggtc cacatatcca tagtcactat
      421 atacgagaat ttcgctattg ttatggagct gttgatgccc atacaggcga atcatttttc
      481 ttaatagctg gtagatgtaa tactgagtgg atgaacgcct ttttagaaga gctttcacaa
      541 gcttatccag atgattatct tttactcgtt atggacaa
//
LOCUS       DAVFER010000105          568 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1105170250
            SAMEA2167659-rid19724873.denovo.105, whole genome shotgun sequence.
ACCESSION   DAVFER010000105 DAVFER010000000
VERSION     DAVFER010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2167659
            Sequence Read Archive: ERR388902
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 568)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 568)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928716.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928716.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 04:07:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,118
            CDSs (total)                      :: 2,073
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 120
            CDSs (without protein)            :: 120
            Pseudo Genes (ambiguous residues) :: 0 of 120
            Pseudo Genes (frameshifted)       :: 67 of 120
            Pseudo Genes (incomplete)         :: 47 of 120
            Pseudo Genes (internal stop)      :: 34 of 120
            Pseudo Genes (multiple problems)  :: 23 of 120
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..568
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2167659-rid19724873.denovo.105"
                     /strain="1105170250"
                     /db_xref="taxon:1313"
     gene            <1..>568
                     /locus_tag="VU534_002112"
     CDS             <1..>568
                     /locus_tag="VU534_002112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HEU1514614.1"
                     /translation="PIRHPERLGKPNAQITYTDDEIQVAKLAGKYTTEDGYIFDPRDI
                     TSDEGDAYVTPHMTHSHWIKKDSLSEAERAAAQAYAKEKGLTPPSTDHQDSGNTEAKG
                     AEAIYNRVKAAKKVPLDRMPYNLQYTVEVKNGSLIIPHYDHYHNIKFEWFDEGLYEAP
                     KGYTLEDLLATVKYYVEHPNERPHSDNGF"
BASE COUNT          183 a          119 c          126 g          140 t
ORIGIN      
        1 ccgattcgtc atccagaacg tttaggaaaa ccaaatgcgc aaattaccta cactgatgat
       61 gagattcaag tagccaagtt ggcaggcaag tacacaacag aagacggtta tatctttgat
      121 cctcgtgata taaccagtga tgagggggat gcctatgtaa ctccacatat gacccatagc
      181 cactggatta aaaaagatag tttgtctgaa gctgagagag cggcagccca ggcttatgct
      241 aaagagaaag gtttgacccc tccttcgaca gaccatcagg attcaggaaa tactgaggca
      301 aaaggagcag aagctatcta caaccgcgtg aaagcagcta agaaggtgcc acttgatcgt
      361 atgccttaca atcttcaata tactgtagaa gtcaaaaacg gtagtttaat catacctcat
      421 tatgaccatt accataacat caaatttgag tggtttgacg aaggccttta tgaggcacct
      481 aaggggtata ctcttgagga tcttttggcg actgtcaagt actatgtcga acatccaaac
      541 gaacgtccgc attcagataa tggttttg
//
LOCUS       DAVFER010000106          501 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1105170250
            SAMEA2167659-rid19724873.denovo.106, whole genome shotgun sequence.
ACCESSION   DAVFER010000106 DAVFER010000000
VERSION     DAVFER010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2167659
            Sequence Read Archive: ERR388902
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 501)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 501)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928716.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928716.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 04:07:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,118
            CDSs (total)                      :: 2,073
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 120
            CDSs (without protein)            :: 120
            Pseudo Genes (ambiguous residues) :: 0 of 120
            Pseudo Genes (frameshifted)       :: 67 of 120
            Pseudo Genes (incomplete)         :: 47 of 120
            Pseudo Genes (internal stop)      :: 34 of 120
            Pseudo Genes (multiple problems)  :: 23 of 120
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..501
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2167659-rid19724873.denovo.106"
                     /strain="1105170250"
                     /db_xref="taxon:1313"
     gene            <1..>501
                     /locus_tag="VU534_002113"
     CDS             <1..>501
                     /locus_tag="VU534_002113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000756162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEU1514615.1"
                     /translation="FGENKIFESIDNLFDIIDGDRGKNYPKSDELFSEEYCLFLNTKN
                     VTKNGFSFDTKQFITKTKDKLLRKGKLERYDIVLTTRGTVGNVAYYDELIKYKHLRIN
                     SGMVILRPKTPNLNQKFIIHVLRNNNYSRVISGSAQPQLPITKLKKILLPLPPLALQN
                     EFADFVV"
BASE COUNT          191 a           75 c           83 g          152 t
ORIGIN      
        1 gtttggggaa aataaaatat ttgaaagcat tgataactta tttgatatta tagatggtga
       61 taggggcaaa aattatccta aatcagatga gttgtttagt gaggagtact gtttattttt
      121 aaatacaaag aatgttacta aaaacggatt ttcattcgat acaaagcaat ttatcactaa
      181 aacaaaggat aaattacttc gaaaaggcaa acttgagcgt tatgatatag tcttgacaac
      241 aagaggtact gttggaaatg tagcgtacta cgatgaatta ataaaatata aacatttacg
      301 tataaattca ggtatggtaa tattacgtcc caagacacca aatctaaatc agaaatttat
      361 tatccatgtt ttaaggaata ataattatag tcgagtgata tcaggaagtg ctcagcctca
      421 gttaccaatt acaaaattaa aaaaaatact tctccccctc cccccactag ccctccaaaa
      481 tgagttcgca gactttgtag t
//
LOCUS       DAVFER010000107          463 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1105170250
            SAMEA2167659-rid19724873.denovo.107, whole genome shotgun sequence.
ACCESSION   DAVFER010000107 DAVFER010000000
VERSION     DAVFER010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2167659
            Sequence Read Archive: ERR388902
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 463)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928716.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928716.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 04:07:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,118
            CDSs (total)                      :: 2,073
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 120
            CDSs (without protein)            :: 120
            Pseudo Genes (ambiguous residues) :: 0 of 120
            Pseudo Genes (frameshifted)       :: 67 of 120
            Pseudo Genes (incomplete)         :: 47 of 120
            Pseudo Genes (internal stop)      :: 34 of 120
            Pseudo Genes (multiple problems)  :: 23 of 120
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2167659-rid19724873.denovo.107"
                     /strain="1105170250"
                     /db_xref="taxon:1313"
     gene            351..463
                     /locus_tag="VU534_002114"
                     /pseudo
     CDS             351..463
                     /locus_tag="VU534_002114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_135354310.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein D"
BASE COUNT          172 a          129 c           89 g           73 t
ORIGIN      
        1 ctgaagatga tactgctgct cttcaaaata aattagctac taaaaaagct gaattggaaa
       61 aaactcaaaa agaattagat gcagctctta atgagttagg ccctgatgga gatgaagaag
      121 aaactccagc gccggctcct caaccagagc aaccagctcc tgcaccaaaa ccagagcaac
      181 cagctccagc tccaaaacca gagcaaccag ctcctgcacc aaaaccagag caaccagctc
      241 cagctccaaa accagagcaa ccagctccag ctccaaaacc agagcaacca gctaagccgg
      301 agaaaccagc tgaagagcct actcaaccag aaaaaccagc cactccaaaa acaggctgga
      361 aacaagaaaa cggtatgtgg tatttctaca atactgatgg ttcaatggca ataggttggc
      421 tccaaaacaa cggttcatgg tactacctaa acgctaacgg cgc
//
LOCUS       DAVFER010000108          393 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1105170250
            SAMEA2167659-rid19724873.denovo.108, whole genome shotgun sequence.
ACCESSION   DAVFER010000108 DAVFER010000000
VERSION     DAVFER010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2167659
            Sequence Read Archive: ERR388902
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 393)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 393)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928716.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928716.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 04:07:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,118
            CDSs (total)                      :: 2,073
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 120
            CDSs (without protein)            :: 120
            Pseudo Genes (ambiguous residues) :: 0 of 120
            Pseudo Genes (frameshifted)       :: 67 of 120
            Pseudo Genes (incomplete)         :: 47 of 120
            Pseudo Genes (internal stop)      :: 34 of 120
            Pseudo Genes (multiple problems)  :: 23 of 120
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..393
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2167659-rid19724873.denovo.108"
                     /strain="1105170250"
                     /db_xref="taxon:1313"
     gene            <1..>393
                     /locus_tag="VU534_002115"
     CDS             <1..>393
                     /locus_tag="VU534_002115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HEU1514616.1"
                     /translation="VPHGDHYHYIPKNELSASELAAAEAYWNGKQGSRPSSSSSYNAN
                     PAQPRLSENHNLTVTPTYHQNQGENISSLLRELYAKPLSERHVESDGLIFDPAQITSR
                     TARGVAVPHGNHYHFIPYEQMSELEKRIA"
BASE COUNT          119 a           95 c           74 g          105 t
ORIGIN      
        1 gttcctcacg gcgaccatta ccattacatt cctaagaatg agttatcagc tagcgagtta
       61 gctgctgcag aagcctattg gaatgggaag cagggatctc gtccttcttc aagttctagt
      121 tataatgcaa atccagctca accaagattg tcagagaacc acaatctgac tgtcactcca
      181 acttatcatc aaaatcaagg ggaaaacatt tcaagccttt tacgtgaatt gtatgctaaa
      241 cccttatcag aacgccatgt ggaatctgat ggccttattt tcgacccagc gcaaatcaca
      301 agtcgaaccg ccagaggtgt agctgtccct catggtaacc attaccactt tatcccttat
      361 gaacaaatgt ctgaattgga aaaacgaatt gct
//
LOCUS       DAVFER010000109          359 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1105170250
            SAMEA2167659-rid19724873.denovo.109, whole genome shotgun sequence.
ACCESSION   DAVFER010000109 DAVFER010000000
VERSION     DAVFER010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2167659
            Sequence Read Archive: ERR388902
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 359)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 359)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928716.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928716.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 04:07:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,118
            CDSs (total)                      :: 2,073
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 120
            CDSs (without protein)            :: 120
            Pseudo Genes (ambiguous residues) :: 0 of 120
            Pseudo Genes (frameshifted)       :: 67 of 120
            Pseudo Genes (incomplete)         :: 47 of 120
            Pseudo Genes (internal stop)      :: 34 of 120
            Pseudo Genes (multiple problems)  :: 23 of 120
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..359
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2167659-rid19724873.denovo.109"
                     /strain="1105170250"
                     /db_xref="taxon:1313"
     gene            complement(<1..347)
                     /locus_tag="VU534_002116"
     CDS             complement(<1..347)
                     /locus_tag="VU534_002116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase C-terminal
                     domain-containing protein"
                     /protein_id="HEU1514617.1"
                     /translation="MDAYLESPEKFEAIKQDLVDEMWKVAQRELATGFYYGTPSENEQ
                     LFGARRKIPEYKFVAEVVSYDDAAQTATIRQRNVINEGDQVEFYGPGFRHFETYIEDL
                     HDAKGNKIDRAPNP"
BASE COUNT           98 a           87 c           69 g          105 t
ORIGIN      
        1 ggatttggag cgcggtcgat tttattgcct ttagcatcat gcaaatcttc aatataggtt
       61 tcaaaatgac ggaaacctgg accataaaac tcaacttggt ccccttcgtt aatgacgttt
      121 cgttgacgaa tagttgctgt ttgtgccgca tcatcataag aaaccacttc agcgacaaac
      181 ttgtactcag ggattttacg acgagcacca aacaactgct cattttcaga tggtgtacca
      241 tagtaaaatc ctgtagccag ttcacgttgg gcaaccttcc acatctcgtc caccaagtct
      301 tgtttgatag cttcaaactt ttcaggactt tcaagatagg catccacagc cgccttgta
//
LOCUS       DAVFER010000110          273 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1105170250
            SAMEA2167659-rid19724873.denovo.110, whole genome shotgun sequence.
ACCESSION   DAVFER010000110 DAVFER010000000
VERSION     DAVFER010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2167659
            Sequence Read Archive: ERR388902
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 273)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 273)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928716.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928716.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 04:07:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,118
            CDSs (total)                      :: 2,073
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 120
            CDSs (without protein)            :: 120
            Pseudo Genes (ambiguous residues) :: 0 of 120
            Pseudo Genes (frameshifted)       :: 67 of 120
            Pseudo Genes (incomplete)         :: 47 of 120
            Pseudo Genes (internal stop)      :: 34 of 120
            Pseudo Genes (multiple problems)  :: 23 of 120
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..273
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2167659-rid19724873.denovo.110"
                     /strain="1105170250"
                     /db_xref="taxon:1313"
     gene            <1..>273
                     /locus_tag="VU534_002117"
     CDS             <1..>273
                     /locus_tag="VU534_002117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000187211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEU1514618.1"
                     /translation="QRIVEAIESALEKVDEYAESYNRLEQLDKEFPDKLKKSILQYAM
                     QGKLVEQDPNDESVEVLLEKIRAEKQKLFEEGKIKKKDLDISIVSQ"
BASE COUNT          124 a           36 c           46 g           67 t
ORIGIN      
        1 aacaacgaat agtagaagca atcgaatcag ctttagaaaa agtagatgaa tatgctgaaa
       61 gttataatag actagaacag ctagataaag aatttccaga taaactaaaa aaatctattc
      121 ttcaatatgc tatgcaagga aaattagttg aacaagaccc aaatgatgaa tcagtcgaag
      181 ttttacttga aaaaatacga gcagaaaaac aaaaactctt tgaagaaggc aagattaaaa
      241 agaaagattt ggacatttct attgtttccc aag
//
LOCUS       DAVFER010000111          251 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1105170250
            SAMEA2167659-rid19724873.denovo.111, whole genome shotgun sequence.
ACCESSION   DAVFER010000111 DAVFER010000000
VERSION     DAVFER010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2167659
            Sequence Read Archive: ERR388902
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 251)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 251)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001928716.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001928716.1
            Genome Coverage       :: 196x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 04:07:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,118
            CDSs (total)                      :: 2,073
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 120
            CDSs (without protein)            :: 120
            Pseudo Genes (ambiguous residues) :: 0 of 120
            Pseudo Genes (frameshifted)       :: 67 of 120
            Pseudo Genes (incomplete)         :: 47 of 120
            Pseudo Genes (internal stop)      :: 34 of 120
            Pseudo Genes (multiple problems)  :: 23 of 120
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..251
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2167659-rid19724873.denovo.111"
                     /strain="1105170250"
                     /db_xref="taxon:1313"
     gene            <1..>251
                     /locus_tag="VU534_002118"
     CDS             <1..>251
                     /locus_tag="VU534_002118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU1514619.1"
                     /translation="SNGAMATGWLQYNGSWYYLNANGDMATGWLQYNGSWYYLNANGD
                     MATGWAKVNGSWYYLNANGAMATGWAKVNGSWYYLNANGS"
BASE COUNT           69 a           57 c           66 g           59 t
ORIGIN      
        1 agcaatggcg ctatggcgac aggctggctc caatacaatg gctcatggta ctacctcaac
       61 gctaatggtg atatggcgac aggatggctc caatacaacg gttcatggta ttacctcaac
      121 gctaatggtg atatggcgac aggatgggct aaagtcaacg gttcatggta ctacctaaac
      181 gctaacggtg ctatggctac aggttgggct aaagtcaacg gttcatggta ctacctaaac
      241 gctaacggtt c
//
